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Network neighborhood for query Sequence : DGKK_HUMAN

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DGKK_HUMAN
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DGKK_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	378	Target Neighborhood Hits	378	Shared Neighborhood Hits	378
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

DGKD_HUMAN
θ value	3.28708e-135 (rank : 2)	NC score	0.782076 (rank : 2)
Query Neighborhood Hits	378	Target Neighborhood Hits	231	Shared Neighborhood Hits	66
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

DGKH_HUMAN
θ value	7.84197e-129 (rank : 3)	NC score	0.778515 (rank : 3)
Query Neighborhood Hits	378	Target Neighborhood Hits	255	Shared Neighborhood Hits	68
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

DGKA_HUMAN
θ value	1.36902e-48 (rank : 4)	NC score	0.739081 (rank : 6)
Query Neighborhood Hits	378	Target Neighborhood Hits	151	Shared Neighborhood Hits	41
SwissProt Accessions	P23743, O75481, O75482, O75483	Gene names	DGKA, DAGK, DAGK1
Domain Architecture
Description	Diacylglycerol kinase alpha (EC 2.7.1.107) (Diglyceride kinase alpha) (DGK-alpha) (DAG kinase alpha) (80 kDa diacylglycerol kinase).

DGKE_MOUSE
θ value	1.67352e-46 (rank : 5)	NC score	0.766601 (rank : 5)
Query Neighborhood Hits	378	Target Neighborhood Hits	30	Shared Neighborhood Hits	20
SwissProt Accessions	Q9R1C6	Gene names	Dgke
Domain Architecture
Description	Diacylglycerol kinase epsilon (EC 2.7.1.107) (Diglyceride kinase epsilon) (DGK-epsilon) (DAG kinase epsilon).

DGKB_HUMAN
θ value	4.86918e-46 (rank : 6)	NC score	0.696841 (rank : 11)
Query Neighborhood Hits	378	Target Neighborhood Hits	238	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y6T7, O75241, Q75MF9, Q75MU7, Q86UI5, Q86UM9, Q9UQ29	Gene names	DGKB, DAGK2, KIAA0718
Domain Architecture
Description	Diacylglycerol kinase beta (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta) (DAG kinase beta) (90 kDa diacylglycerol kinase).

DGKG_MOUSE
θ value	4.86918e-46 (rank : 7)	NC score	0.721132 (rank : 9)
Query Neighborhood Hits	378	Target Neighborhood Hits	188	Shared Neighborhood Hits	41
SwissProt Accessions	Q91WG7	Gene names	Dgkg, Dagk3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma) (88 kDa diacylglycerol kinase).

DGKA_MOUSE
θ value	3.15612e-45 (rank : 8)	NC score	0.726448 (rank : 7)
Query Neighborhood Hits	378	Target Neighborhood Hits	146	Shared Neighborhood Hits	35
SwissProt Accessions	O88673, Q922X2	Gene names	Dgka, Dagk1
Domain Architecture
Description	Diacylglycerol kinase alpha (EC 2.7.1.107) (Diglyceride kinase alpha) (DGK-alpha) (DAG kinase alpha) (80 kDa diacylglycerol kinase).

DGKE_HUMAN
θ value	4.55743e-44 (rank : 9)	NC score	0.767798 (rank : 4)
Query Neighborhood Hits	378	Target Neighborhood Hits	32	Shared Neighborhood Hits	23
SwissProt Accessions	P52429, Q9UKQ3	Gene names	DGKE, DAGK5
Domain Architecture
Description	Diacylglycerol kinase epsilon (EC 2.7.1.107) (Diglyceride kinase epsilon) (DGK-epsilon) (DAG kinase epsilon).

DGKG_HUMAN
θ value	2.95404e-43 (rank : 10)	NC score	0.723012 (rank : 8)
Query Neighborhood Hits	378	Target Neighborhood Hits	171	Shared Neighborhood Hits	38
SwissProt Accessions	P49619	Gene names	DGKG, DAGK3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma).

DGKI_HUMAN
θ value	6.82597e-32 (rank : 11)	NC score	0.605362 (rank : 14)
Query Neighborhood Hits	378	Target Neighborhood Hits	609	Shared Neighborhood Hits	30
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

DGKZ_MOUSE
θ value	2.59387e-31 (rank : 12)	NC score	0.616796 (rank : 12)
Query Neighborhood Hits	378	Target Neighborhood Hits	542	Shared Neighborhood Hits	26
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

DGKZ_HUMAN
θ value	3.3877e-31 (rank : 13)	NC score	0.612588 (rank : 13)
Query Neighborhood Hits	378	Target Neighborhood Hits	551	Shared Neighborhood Hits	23
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

DGKQ_HUMAN
θ value	2.86786e-30 (rank : 14)	NC score	0.708476 (rank : 10)
Query Neighborhood Hits	378	Target Neighborhood Hits	131	Shared Neighborhood Hits	41
SwissProt Accessions	P52824	Gene names	DGKQ, DAGK4
Domain Architecture
Description	Diacylglycerol kinase theta (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta) (DAG kinase theta).

STAT2_MOUSE
θ value	5.8054e-15 (rank : 15)	NC score	0.105414 (rank : 160)
Query Neighborhood Hits	378	Target Neighborhood Hits	175	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

SPR1B_MOUSE
θ value	1.09485e-13 (rank : 16)	NC score	0.188169 (rank : 26)
Query Neighborhood Hits	378	Target Neighborhood Hits	395	Shared Neighborhood Hits	61
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

MUC1_HUMAN
θ value	1.74796e-11 (rank : 17)	NC score	0.128051 (rank : 90)
Query Neighborhood Hits	378	Target Neighborhood Hits	975	Shared Neighborhood Hits	112
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

OGFR_HUMAN
θ value	7.34386e-10 (rank : 18)	NC score	0.161840 (rank : 43)
Query Neighborhood Hits	378	Target Neighborhood Hits	1582	Shared Neighborhood Hits	171
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

SPR1A_MOUSE
θ value	4.76016e-09 (rank : 19)	NC score	0.178800 (rank : 35)
Query Neighborhood Hits	378	Target Neighborhood Hits	343	Shared Neighborhood Hits	49
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

NFH_MOUSE
θ value	1.80886e-08 (rank : 20)	NC score	0.102940 (rank : 172)
Query Neighborhood Hits	378	Target Neighborhood Hits	2247	Shared Neighborhood Hits	189
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

MDC1_MOUSE
θ value	1.99992e-07 (rank : 21)	NC score	0.181601 (rank : 33)
Query Neighborhood Hits	378	Target Neighborhood Hits	998	Shared Neighborhood Hits	132
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

SPRR3_HUMAN
θ value	2.61198e-07 (rank : 22)	NC score	0.220293 (rank : 19)
Query Neighborhood Hits	378	Target Neighborhood Hits	102	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

FA47B_HUMAN
θ value	9.92553e-07 (rank : 23)	NC score	0.150841 (rank : 53)
Query Neighborhood Hits	378	Target Neighborhood Hits	431	Shared Neighborhood Hits	72
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

MDC1_HUMAN
θ value	3.77169e-06 (rank : 24)	NC score	0.187408 (rank : 28)
Query Neighborhood Hits	378	Target Neighborhood Hits	1446	Shared Neighborhood Hits	167
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

IASPP_MOUSE
θ value	4.92598e-06 (rank : 25)	NC score	0.118505 (rank : 109)
Query Neighborhood Hits	378	Target Neighborhood Hits	1024	Shared Neighborhood Hits	101
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

SELPL_MOUSE
θ value	8.40245e-06 (rank : 26)	NC score	0.165948 (rank : 41)
Query Neighborhood Hits	378	Target Neighborhood Hits	588	Shared Neighborhood Hits	107
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SON_HUMAN
θ value	1.09739e-05 (rank : 27)	NC score	0.149916 (rank : 56)
Query Neighborhood Hits	378	Target Neighborhood Hits	1568	Shared Neighborhood Hits	173
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SEPT9_HUMAN
θ value	1.87187e-05 (rank : 28)	NC score	0.081384 (rank : 287)
Query Neighborhood Hits	378	Target Neighborhood Hits	706	Shared Neighborhood Hits	105
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

ASPP1_MOUSE
θ value	2.44474e-05 (rank : 29)	NC score	0.115325 (rank : 116)
Query Neighborhood Hits	378	Target Neighborhood Hits	1244	Shared Neighborhood Hits	111
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

RGS3_MOUSE
θ value	2.44474e-05 (rank : 30)	NC score	0.125223 (rank : 94)
Query Neighborhood Hits	378	Target Neighborhood Hits	1621	Shared Neighborhood Hits	173
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

K1802_MOUSE
θ value	3.19293e-05 (rank : 31)	NC score	0.116040 (rank : 113)
Query Neighborhood Hits	378	Target Neighborhood Hits	1596	Shared Neighborhood Hits	155
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

CK024_HUMAN
θ value	9.29e-05 (rank : 32)	NC score	0.205134 (rank : 21)
Query Neighborhood Hits	378	Target Neighborhood Hits	408	Shared Neighborhood Hits	96
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

GP152_HUMAN
θ value	0.000121331 (rank : 33)	NC score	0.087643 (rank : 250)
Query Neighborhood Hits	378	Target Neighborhood Hits	636	Shared Neighborhood Hits	89
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

MLL3_HUMAN
θ value	0.000121331 (rank : 34)	NC score	0.109678 (rank : 137)
Query Neighborhood Hits	378	Target Neighborhood Hits	1644	Shared Neighborhood Hits	147
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PCLO_MOUSE
θ value	0.000121331 (rank : 35)	NC score	0.153398 (rank : 51)
Query Neighborhood Hits	378	Target Neighborhood Hits	2275	Shared Neighborhood Hits	214
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

KPCL_HUMAN
θ value	0.000158464 (rank : 36)	NC score	0.089750 (rank : 240)
Query Neighborhood Hits	378	Target Neighborhood Hits	887	Shared Neighborhood Hits	51
SwissProt Accessions	P24723, Q16246	Gene names	PRKCH, PKCL
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

NACAM_MOUSE
θ value	0.000158464 (rank : 37)	NC score	0.165294 (rank : 42)
Query Neighborhood Hits	378	Target Neighborhood Hits	1866	Shared Neighborhood Hits	204
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

RGS3_HUMAN
θ value	0.000158464 (rank : 38)	NC score	0.092796 (rank : 218)
Query Neighborhood Hits	378	Target Neighborhood Hits	1375	Shared Neighborhood Hits	144
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

KPCE_MOUSE
θ value	0.00020696 (rank : 39)	NC score	0.084764 (rank : 267)
Query Neighborhood Hits	378	Target Neighborhood Hits	906	Shared Neighborhood Hits	51
SwissProt Accessions	P16054	Gene names	Prkce, Pkce, Pkcea
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

KPCL_MOUSE
θ value	0.00020696 (rank : 40)	NC score	0.087730 (rank : 249)
Query Neighborhood Hits	378	Target Neighborhood Hits	891	Shared Neighborhood Hits	51
SwissProt Accessions	P23298	Gene names	Prkch, Pkch
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

KPCD_MOUSE
θ value	0.00035302 (rank : 41)	NC score	0.088002 (rank : 247)
Query Neighborhood Hits	378	Target Neighborhood Hits	888	Shared Neighborhood Hits	50
SwissProt Accessions	P28867, Q91V85, Q9Z333	Gene names	Prkcd, Pkcd
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

KPCE_HUMAN
θ value	0.00035302 (rank : 42)	NC score	0.083883 (rank : 274)
Query Neighborhood Hits	378	Target Neighborhood Hits	906	Shared Neighborhood Hits	51
SwissProt Accessions	Q02156, Q53SL4, Q53SM5, Q9UE81	Gene names	PRKCE, PKCE
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

KPCT_HUMAN
θ value	0.00035302 (rank : 43)	NC score	0.083939 (rank : 270)
Query Neighborhood Hits	378	Target Neighborhood Hits	897	Shared Neighborhood Hits	51
SwissProt Accessions	Q04759, Q3MJF1, Q64FY5, Q9H508, Q9H549	Gene names	PRKCQ, PRKCT
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

KPCT_MOUSE
θ value	0.00035302 (rank : 44)	NC score	0.084287 (rank : 268)
Query Neighborhood Hits	378	Target Neighborhood Hits	895	Shared Neighborhood Hits	51
SwissProt Accessions	Q02111	Gene names	Prkcq, Pkcq
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

CD248_HUMAN
θ value	0.000461057 (rank : 45)	NC score	0.065374 (rank : 392)
Query Neighborhood Hits	378	Target Neighborhood Hits	679	Shared Neighborhood Hits	75
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

DAPP1_MOUSE
θ value	0.000461057 (rank : 46)	NC score	0.112006 (rank : 127)
Query Neighborhood Hits	378	Target Neighborhood Hits	225	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

CDN1C_MOUSE
θ value	0.000602161 (rank : 47)	NC score	0.139127 (rank : 71)
Query Neighborhood Hits	378	Target Neighborhood Hits	161	Shared Neighborhood Hits	49
SwissProt Accessions	P49919	Gene names	Cdkn1c, Kip2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

KPCD_HUMAN
θ value	0.000602161 (rank : 48)	NC score	0.087575 (rank : 251)
Query Neighborhood Hits	378	Target Neighborhood Hits	900	Shared Neighborhood Hits	50
SwissProt Accessions	Q05655, Q15144	Gene names	PRKCD
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

LPP_HUMAN
θ value	0.000602161 (rank : 49)	NC score	0.068465 (rank : 364)
Query Neighborhood Hits	378	Target Neighborhood Hits	775	Shared Neighborhood Hits	83
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

IF4G1_MOUSE
θ value	0.000786445 (rank : 50)	NC score	0.096318 (rank : 205)
Query Neighborhood Hits	378	Target Neighborhood Hits	534	Shared Neighborhood Hits	84
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

PRRT3_HUMAN
θ value	0.000786445 (rank : 51)	NC score	0.131985 (rank : 83)
Query Neighborhood Hits	378	Target Neighborhood Hits	998	Shared Neighborhood Hits	137
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SPRR3_MOUSE
θ value	0.000786445 (rank : 52)	NC score	0.203690 (rank : 22)
Query Neighborhood Hits	378	Target Neighborhood Hits	106	Shared Neighborhood Hits	36
SwissProt Accessions	O09116	Gene names	Sprr3
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta).

CAMKV_HUMAN
θ value	0.00102713 (rank : 53)	NC score	0.048559 (rank : 572)
Query Neighborhood Hits	378	Target Neighborhood Hits	1084	Shared Neighborhood Hits	87
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

FA47A_HUMAN
θ value	0.00102713 (rank : 54)	NC score	0.147730 (rank : 58)
Query Neighborhood Hits	378	Target Neighborhood Hits	451	Shared Neighborhood Hits	59
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

PDLI7_HUMAN
θ value	0.00102713 (rank : 55)	NC score	0.041458 (rank : 589)
Query Neighborhood Hits	378	Target Neighborhood Hits	547	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

LR37B_HUMAN
θ value	0.00134147 (rank : 56)	NC score	0.080048 (rank : 293)
Query Neighborhood Hits	378	Target Neighborhood Hits	392	Shared Neighborhood Hits	48
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

MYO15_MOUSE
θ value	0.00134147 (rank : 57)	NC score	0.050675 (rank : 558)
Query Neighborhood Hits	378	Target Neighborhood Hits	467	Shared Neighborhood Hits	72
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NCOA6_HUMAN
θ value	0.00134147 (rank : 58)	NC score	0.125913 (rank : 92)
Query Neighborhood Hits	378	Target Neighborhood Hits	1202	Shared Neighborhood Hits	144
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

PSL1_HUMAN
θ value	0.00134147 (rank : 59)	NC score	0.078740 (rank : 300)
Query Neighborhood Hits	378	Target Neighborhood Hits	650	Shared Neighborhood Hits	68
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

DAPP1_HUMAN
θ value	0.00175202 (rank : 60)	NC score	0.109221 (rank : 140)
Query Neighborhood Hits	378	Target Neighborhood Hits	227	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

IWS1_MOUSE
θ value	0.00175202 (rank : 61)	NC score	0.090467 (rank : 234)
Query Neighborhood Hits	378	Target Neighborhood Hits	1258	Shared Neighborhood Hits	106
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

KPCD3_MOUSE
θ value	0.00175202 (rank : 62)	NC score	0.069719 (rank : 357)
Query Neighborhood Hits	378	Target Neighborhood Hits	901	Shared Neighborhood Hits	51
SwissProt Accessions	Q8K1Y2	Gene names	Prkd3, Prkcn
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu).

MAGE1_HUMAN
θ value	0.00175202 (rank : 63)	NC score	0.100243 (rank : 184)
Query Neighborhood Hits	378	Target Neighborhood Hits	1389	Shared Neighborhood Hits	158
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

AMPH_HUMAN
θ value	0.00228821 (rank : 64)	NC score	0.105459 (rank : 159)
Query Neighborhood Hits	378	Target Neighborhood Hits	455	Shared Neighborhood Hits	66
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

DP13B_HUMAN
θ value	0.00228821 (rank : 65)	NC score	0.108263 (rank : 146)
Query Neighborhood Hits	378	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NEU8, Q8N4R7, Q9NVL2	Gene names	DIP13B, APPL2
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 beta (Dip13 beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2).

DP13B_MOUSE
θ value	0.00298849 (rank : 66)	NC score	0.106562 (rank : 154)
Query Neighborhood Hits	378	Target Neighborhood Hits	58	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K3G9, Q99LT7	Gene names	Dip13b, Appl2, Dip3b
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 beta (Dip13 beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2).

OSBP2_MOUSE
θ value	0.00298849 (rank : 67)	NC score	0.037706 (rank : 610)
Query Neighborhood Hits	378	Target Neighborhood Hits	150	Shared Neighborhood Hits	23
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

CENB2_HUMAN
θ value	0.00390308 (rank : 68)	NC score	0.091089 (rank : 230)
Query Neighborhood Hits	378	Target Neighborhood Hits	425	Shared Neighborhood Hits	38
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

GP152_MOUSE
θ value	0.00390308 (rank : 69)	NC score	0.062549 (rank : 411)
Query Neighborhood Hits	378	Target Neighborhood Hits	607	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

MLL3_MOUSE
θ value	0.00390308 (rank : 70)	NC score	0.103189 (rank : 171)
Query Neighborhood Hits	378	Target Neighborhood Hits	1399	Shared Neighborhood Hits	139
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

LR37A_HUMAN
θ value	0.00509761 (rank : 71)	NC score	0.107265 (rank : 152)
Query Neighborhood Hits	378	Target Neighborhood Hits	720	Shared Neighborhood Hits	95
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

SNPC4_HUMAN
θ value	0.00509761 (rank : 72)	NC score	0.098700 (rank : 193)
Query Neighborhood Hits	378	Target Neighborhood Hits	589	Shared Neighborhood Hits	80
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

SON_MOUSE
θ value	0.00509761 (rank : 73)	NC score	0.160312 (rank : 44)
Query Neighborhood Hits	378	Target Neighborhood Hits	957	Shared Neighborhood Hits	141
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

IWS1_HUMAN
θ value	0.00665767 (rank : 74)	NC score	0.087454 (rank : 252)
Query Neighborhood Hits	378	Target Neighborhood Hits	1241	Shared Neighborhood Hits	93
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

ATF2_HUMAN
θ value	0.00869519 (rank : 75)	NC score	0.078683 (rank : 301)
Query Neighborhood Hits	378	Target Neighborhood Hits	402	Shared Neighborhood Hits	43
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

ATF2_MOUSE
θ value	0.00869519 (rank : 76)	NC score	0.077039 (rank : 314)
Query Neighborhood Hits	378	Target Neighborhood Hits	397	Shared Neighborhood Hits	43
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

MAP1B_MOUSE
θ value	0.00869519 (rank : 77)	NC score	0.086677 (rank : 258)
Query Neighborhood Hits	378	Target Neighborhood Hits	977	Shared Neighborhood Hits	84
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

RASA3_HUMAN
θ value	0.00869519 (rank : 78)	NC score	0.076184 (rank : 320)
Query Neighborhood Hits	378	Target Neighborhood Hits	166	Shared Neighborhood Hits	31
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

RIMB1_HUMAN
θ value	0.00869519 (rank : 79)	NC score	0.062378 (rank : 416)
Query Neighborhood Hits	378	Target Neighborhood Hits	1479	Shared Neighborhood Hits	111
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

MYO15_HUMAN
θ value	0.0113563 (rank : 80)	NC score	0.051303 (rank : 549)
Query Neighborhood Hits	378	Target Neighborhood Hits	671	Shared Neighborhood Hits	92
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PCLO_HUMAN
θ value	0.0113563 (rank : 81)	NC score	0.155308 (rank : 49)
Query Neighborhood Hits	378	Target Neighborhood Hits	2046	Shared Neighborhood Hits	215
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SEPT9_MOUSE
θ value	0.0113563 (rank : 82)	NC score	0.051920 (rank : 541)
Query Neighborhood Hits	378	Target Neighborhood Hits	238	Shared Neighborhood Hits	33
SwissProt Accessions	Q80UG5, Q3URP2, Q80TM7, Q9QYX9	Gene names	Sept9, Kiaa0991, Sint1
Domain Architecture	No domain graphic available
Description	Septin-9 (SL3-3 integration site 1 protein).

BIN1_HUMAN
θ value	0.0148317 (rank : 83)	NC score	0.081556 (rank : 285)
Query Neighborhood Hits	378	Target Neighborhood Hits	335	Shared Neighborhood Hits	39
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

JPH2_HUMAN
θ value	0.0148317 (rank : 84)	NC score	0.064463 (rank : 399)
Query Neighborhood Hits	378	Target Neighborhood Hits	639	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

SAPS1_HUMAN
θ value	0.0148317 (rank : 85)	NC score	0.082502 (rank : 281)
Query Neighborhood Hits	378	Target Neighborhood Hits	704	Shared Neighborhood Hits	99
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

ZIMP7_MOUSE
θ value	0.0148317 (rank : 86)	NC score	0.065180 (rank : 394)
Query Neighborhood Hits	378	Target Neighborhood Hits	566	Shared Neighborhood Hits	64
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ZN409_HUMAN
θ value	0.0148317 (rank : 87)	NC score	0.047834 (rank : 574)
Query Neighborhood Hits	378	Target Neighborhood Hits	842	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

BCL9_HUMAN
θ value	0.0252991 (rank : 88)	NC score	0.109813 (rank : 136)
Query Neighborhood Hits	378	Target Neighborhood Hits	1008	Shared Neighborhood Hits	121
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BSN_MOUSE
θ value	0.0252991 (rank : 89)	NC score	0.147148 (rank : 60)
Query Neighborhood Hits	378	Target Neighborhood Hits	2057	Shared Neighborhood Hits	206
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CEL_HUMAN
θ value	0.0252991 (rank : 90)	NC score	0.057351 (rank : 467)
Query Neighborhood Hits	378	Target Neighborhood Hits	896	Shared Neighborhood Hits	98
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CO039_MOUSE
θ value	0.0252991 (rank : 91)	NC score	0.120210 (rank : 103)
Query Neighborhood Hits	378	Target Neighborhood Hits	445	Shared Neighborhood Hits	100
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

JIP3_HUMAN
θ value	0.0252991 (rank : 92)	NC score	0.042007 (rank : 586)
Query Neighborhood Hits	378	Target Neighborhood Hits	1039	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

KPCD1_MOUSE
θ value	0.0252991 (rank : 93)	NC score	0.066390 (rank : 385)
Query Neighborhood Hits	378	Target Neighborhood Hits	891	Shared Neighborhood Hits	50
SwissProt Accessions	Q62101	Gene names	Prkd1, Pkcm, Pkd, Prkcm
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

RASA3_MOUSE
θ value	0.0252991 (rank : 94)	NC score	0.079155 (rank : 295)
Query Neighborhood Hits	378	Target Neighborhood Hits	144	Shared Neighborhood Hits	29
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

FOXO4_HUMAN
θ value	0.0330416 (rank : 95)	NC score	0.030732 (rank : 626)
Query Neighborhood Hits	378	Target Neighborhood Hits	197	Shared Neighborhood Hits	20
SwissProt Accessions	P98177, O43821, Q13720, Q3KPF1, Q8TDK9	Gene names	MLLT7, AFX, AFX1, FOXO4
Domain Architecture
Description	Fork head domain transcription factor AFX1 (Forkhead box protein O4).

KPCD3_HUMAN
θ value	0.0330416 (rank : 96)	NC score	0.068200 (rank : 370)
Query Neighborhood Hits	378	Target Neighborhood Hits	895	Shared Neighborhood Hits	50
SwissProt Accessions	O94806	Gene names	PRKD3, EPK2, PRKCN
Domain Architecture
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu) (Protein kinase EPK2).

KPCI_HUMAN
θ value	0.0330416 (rank : 97)	NC score	0.062824 (rank : 407)
Query Neighborhood Hits	378	Target Neighborhood Hits	885	Shared Neighborhood Hits	48
SwissProt Accessions	P41743, Q8WW06	Gene names	PRKCI, DXS1179E
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota).

FHOD1_HUMAN
θ value	0.0431538 (rank : 98)	NC score	0.056706 (rank : 474)
Query Neighborhood Hits	378	Target Neighborhood Hits	184	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

K1802_HUMAN
θ value	0.0431538 (rank : 99)	NC score	0.125652 (rank : 93)
Query Neighborhood Hits	378	Target Neighborhood Hits	1378	Shared Neighborhood Hits	162
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

KPCD1_HUMAN
θ value	0.0431538 (rank : 100)	NC score	0.065746 (rank : 390)
Query Neighborhood Hits	378	Target Neighborhood Hits	901	Shared Neighborhood Hits	50
SwissProt Accessions	Q15139	Gene names	PRKD1, PKD, PKD1, PRKCM
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

KPCD2_HUMAN
θ value	0.0431538 (rank : 101)	NC score	0.066258 (rank : 386)
Query Neighborhood Hits	378	Target Neighborhood Hits	910	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BZL6, Q8TB08, Q9P0T6, Q9Y3X8	Gene names	PRKD2, PKD2
Domain Architecture
Description	Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2).

MTSS1_MOUSE
θ value	0.0431538 (rank : 102)	NC score	0.086849 (rank : 257)
Query Neighborhood Hits	378	Target Neighborhood Hits	592	Shared Neighborhood Hits	70
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

SPR1A_HUMAN
θ value	0.0431538 (rank : 103)	NC score	0.145210 (rank : 61)
Query Neighborhood Hits	378	Target Neighborhood Hits	136	Shared Neighborhood Hits	25
SwissProt Accessions	P35321, Q9UDG4	Gene names	SPRR1A
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein IA) (SPR-IA) (SPRK) (19 kDa pancornulin).

TARSH_HUMAN
θ value	0.0431538 (rank : 104)	NC score	0.150591 (rank : 54)
Query Neighborhood Hits	378	Target Neighborhood Hits	768	Shared Neighborhood Hits	110
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

AATK_HUMAN
θ value	0.0563607 (rank : 105)	NC score	0.042304 (rank : 585)
Query Neighborhood Hits	378	Target Neighborhood Hits	1243	Shared Neighborhood Hits	103
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

KPCI_MOUSE
θ value	0.0563607 (rank : 106)	NC score	0.062531 (rank : 413)
Query Neighborhood Hits	378	Target Neighborhood Hits	888	Shared Neighborhood Hits	48
SwissProt Accessions	Q62074	Gene names	Prkci, Pkcl
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota).

MEGF9_MOUSE
θ value	0.0563607 (rank : 107)	NC score	0.054914 (rank : 498)
Query Neighborhood Hits	378	Target Neighborhood Hits	896	Shared Neighborhood Hits	89
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

AATK_MOUSE
θ value	0.0736092 (rank : 108)	NC score	0.038169 (rank : 609)
Query Neighborhood Hits	378	Target Neighborhood Hits	942	Shared Neighborhood Hits	76
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

CAR10_HUMAN
θ value	0.0736092 (rank : 109)	NC score	0.028959 (rank : 636)
Query Neighborhood Hits	378	Target Neighborhood Hits	569	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

CEND1_MOUSE
θ value	0.0736092 (rank : 110)	NC score	0.055352 (rank : 490)
Query Neighborhood Hits	378	Target Neighborhood Hits	260	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

MAP1A_HUMAN
θ value	0.0736092 (rank : 111)	NC score	0.085428 (rank : 263)
Query Neighborhood Hits	378	Target Neighborhood Hits	1626	Shared Neighborhood Hits	124
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MTR1L_HUMAN
θ value	0.0736092 (rank : 112)	NC score	0.009234 (rank : 716)
Query Neighborhood Hits	378	Target Neighborhood Hits	1180	Shared Neighborhood Hits	50
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

MYBPH_MOUSE
θ value	0.0736092 (rank : 113)	NC score	0.029116 (rank : 634)
Query Neighborhood Hits	378	Target Neighborhood Hits	290	Shared Neighborhood Hits	21
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

CENB5_HUMAN
θ value	0.0961366 (rank : 114)	NC score	0.086117 (rank : 262)
Query Neighborhood Hits	378	Target Neighborhood Hits	395	Shared Neighborhood Hits	42
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

FGD4_MOUSE
θ value	0.0961366 (rank : 115)	NC score	0.061352 (rank : 421)
Query Neighborhood Hits	378	Target Neighborhood Hits	227	Shared Neighborhood Hits	35
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

GON4L_HUMAN
θ value	0.0961366 (rank : 116)	NC score	0.057861 (rank : 462)
Query Neighborhood Hits	378	Target Neighborhood Hits	555	Shared Neighborhood Hits	63
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

KPCZ_MOUSE
θ value	0.0961366 (rank : 117)	NC score	0.067962 (rank : 374)
Query Neighborhood Hits	378	Target Neighborhood Hits	882	Shared Neighborhood Hits	46
SwissProt Accessions	Q02956	Gene names	Prkcz, Pkcz
Domain Architecture
Description	Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta).

NPAS4_MOUSE
θ value	0.0961366 (rank : 118)	NC score	0.063559 (rank : 401)
Query Neighborhood Hits	378	Target Neighborhood Hits	245	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

PI5PA_HUMAN
θ value	0.0961366 (rank : 119)	NC score	0.108501 (rank : 144)
Query Neighborhood Hits	378	Target Neighborhood Hits	749	Shared Neighborhood Hits	126
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

RTP3_MOUSE
θ value	0.0961366 (rank : 120)	NC score	0.087363 (rank : 254)
Query Neighborhood Hits	378	Target Neighborhood Hits	374	Shared Neighborhood Hits	64
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

SPR1B_HUMAN
θ value	0.0961366 (rank : 121)	NC score	0.141703 (rank : 65)
Query Neighborhood Hits	378	Target Neighborhood Hits	102	Shared Neighborhood Hits	16
SwissProt Accessions	P22528, P22529, P22530, Q5T524	Gene names	SPRR1B
Domain Architecture	No domain graphic available
Description	Cornifin B (Small proline-rich protein IB) (SPR-IB) (14.9 kDa pancornulin).

SRC8_MOUSE
θ value	0.0961366 (rank : 122)	NC score	0.033734 (rank : 618)
Query Neighborhood Hits	378	Target Neighborhood Hits	292	Shared Neighborhood Hits	22
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

ZN687_HUMAN
θ value	0.0961366 (rank : 123)	NC score	0.025585 (rank : 650)
Query Neighborhood Hits	378	Target Neighborhood Hits	1244	Shared Neighborhood Hits	90
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

MTSS1_HUMAN
θ value	0.125558 (rank : 124)	NC score	0.078909 (rank : 298)
Query Neighborhood Hits	378	Target Neighborhood Hits	504	Shared Neighborhood Hits	55
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

PHC2_HUMAN
θ value	0.125558 (rank : 125)	NC score	0.064932 (rank : 397)
Query Neighborhood Hits	378	Target Neighborhood Hits	388	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

PRGC2_MOUSE
θ value	0.125558 (rank : 126)	NC score	0.054533 (rank : 501)
Query Neighborhood Hits	378	Target Neighborhood Hits	225	Shared Neighborhood Hits	31
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

BAG3_MOUSE
θ value	0.163984 (rank : 127)	NC score	0.116348 (rank : 112)
Query Neighborhood Hits	378	Target Neighborhood Hits	513	Shared Neighborhood Hits	106
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

BAZ2A_MOUSE
θ value	0.163984 (rank : 128)	NC score	0.070364 (rank : 351)
Query Neighborhood Hits	378	Target Neighborhood Hits	744	Shared Neighborhood Hits	90
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

CAMKV_MOUSE
θ value	0.163984 (rank : 129)	NC score	0.039087 (rank : 600)
Query Neighborhood Hits	378	Target Neighborhood Hits	848	Shared Neighborhood Hits	56
SwissProt Accessions	Q3UHL1, Q8VD20	Gene names	Camkv
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

CENB1_HUMAN
θ value	0.163984 (rank : 130)	NC score	0.077916 (rank : 308)
Query Neighborhood Hits	378	Target Neighborhood Hits	383	Shared Neighborhood Hits	39
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

DIDO1_HUMAN
θ value	0.163984 (rank : 131)	NC score	0.075391 (rank : 324)
Query Neighborhood Hits	378	Target Neighborhood Hits	960	Shared Neighborhood Hits	108
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

EFS_HUMAN
θ value	0.163984 (rank : 132)	NC score	0.088747 (rank : 245)
Query Neighborhood Hits	378	Target Neighborhood Hits	348	Shared Neighborhood Hits	67
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

K1543_HUMAN
θ value	0.163984 (rank : 133)	NC score	0.100236 (rank : 185)
Query Neighborhood Hits	378	Target Neighborhood Hits	435	Shared Neighborhood Hits	70
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

KLF17_HUMAN
θ value	0.163984 (rank : 134)	NC score	0.008739 (rank : 720)
Query Neighborhood Hits	378	Target Neighborhood Hits	882	Shared Neighborhood Hits	57
SwissProt Accessions	Q5JT82, Q86VQ7, Q8N805	Gene names	KLF17, ZNF393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393).

NFAC1_HUMAN
θ value	0.163984 (rank : 135)	NC score	0.060365 (rank : 433)
Query Neighborhood Hits	378	Target Neighborhood Hits	312	Shared Neighborhood Hits	64
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

PKHA1_HUMAN
θ value	0.163984 (rank : 136)	NC score	0.107763 (rank : 149)
Query Neighborhood Hits	378	Target Neighborhood Hits	127	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

ZAN_MOUSE
θ value	0.163984 (rank : 137)	NC score	0.061025 (rank : 426)
Query Neighborhood Hits	378	Target Neighborhood Hits	808	Shared Neighborhood Hits	60
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

ANK2_HUMAN
θ value	0.21417 (rank : 138)	NC score	0.062067 (rank : 419)
Query Neighborhood Hits	378	Target Neighborhood Hits	1615	Shared Neighborhood Hits	138
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ASPP1_HUMAN
θ value	0.21417 (rank : 139)	NC score	0.104900 (rank : 164)
Query Neighborhood Hits	378	Target Neighborhood Hits	956	Shared Neighborhood Hits	89
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

BAZ2A_HUMAN
θ value	0.21417 (rank : 140)	NC score	0.066713 (rank : 382)
Query Neighborhood Hits	378	Target Neighborhood Hits	780	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

FGD1_HUMAN
θ value	0.21417 (rank : 141)	NC score	0.096455 (rank : 202)
Query Neighborhood Hits	378	Target Neighborhood Hits	367	Shared Neighborhood Hits	85
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

MAP1B_HUMAN
θ value	0.21417 (rank : 142)	NC score	0.092322 (rank : 222)
Query Neighborhood Hits	378	Target Neighborhood Hits	903	Shared Neighborhood Hits	80
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MIS_HUMAN
θ value	0.21417 (rank : 143)	NC score	0.040995 (rank : 591)
Query Neighborhood Hits	378	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	P03971, O75246	Gene names	AMH, MIF
Domain Architecture
Description	Muellerian-inhibiting factor precursor (MIS) (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance).

NFM_HUMAN
θ value	0.21417 (rank : 144)	NC score	0.031232 (rank : 621)
Query Neighborhood Hits	378	Target Neighborhood Hits	1328	Shared Neighborhood Hits	93
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

PER2_MOUSE
θ value	0.21417 (rank : 145)	NC score	0.028805 (rank : 637)
Query Neighborhood Hits	378	Target Neighborhood Hits	325	Shared Neighborhood Hits	31
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

PKHA1_MOUSE
θ value	0.21417 (rank : 146)	NC score	0.104570 (rank : 166)
Query Neighborhood Hits	378	Target Neighborhood Hits	120	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

SFR14_MOUSE
θ value	0.21417 (rank : 147)	NC score	0.043041 (rank : 583)
Query Neighborhood Hits	378	Target Neighborhood Hits	238	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CH09, Q6PG19, Q80UY8, Q8BY32, Q8CFM0	Gene names	Sfrs14
Domain Architecture	No domain graphic available
Description	Putative splicing factor, arginine/serine-rich 14 (Arginine/serine- rich-splicing factor 14).

TNR8_MOUSE
θ value	0.21417 (rank : 148)	NC score	0.043372 (rank : 582)
Query Neighborhood Hits	378	Target Neighborhood Hits	208	Shared Neighborhood Hits	19
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

ERR1_HUMAN
θ value	0.279714 (rank : 149)	NC score	0.010843 (rank : 713)
Query Neighborhood Hits	378	Target Neighborhood Hits	157	Shared Neighborhood Hits	17
SwissProt Accessions	P11474, Q14514	Gene names	ESRRA, ERR1, ESRL1, NR3B1
Domain Architecture
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR- alpha) (Estrogen receptor-like 1).

ETV3_HUMAN
θ value	0.279714 (rank : 150)	NC score	0.038818 (rank : 601)
Query Neighborhood Hits	378	Target Neighborhood Hits	312	Shared Neighborhood Hits	45
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

FGD4_HUMAN
θ value	0.279714 (rank : 151)	NC score	0.060611 (rank : 431)
Query Neighborhood Hits	378	Target Neighborhood Hits	219	Shared Neighborhood Hits	31
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

GLYG2_HUMAN
θ value	0.279714 (rank : 152)	NC score	0.038308 (rank : 607)
Query Neighborhood Hits	378	Target Neighborhood Hits	65	Shared Neighborhood Hits	12
SwissProt Accessions	O15488, O15485, O15486, O15487, O15489, O15490	Gene names	GYG2
Domain Architecture
Description	Glycogenin-2 (EC 2.4.1.186) (GN-2) (GN2).

KPCZ_HUMAN
θ value	0.279714 (rank : 153)	NC score	0.065038 (rank : 395)
Query Neighborhood Hits	378	Target Neighborhood Hits	884	Shared Neighborhood Hits	46
SwissProt Accessions	Q05513, Q15207, Q5SYT5, Q969S4	Gene names	PRKCZ, PKC2
Domain Architecture
Description	Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta).

MILK1_MOUSE
θ value	0.279714 (rank : 154)	NC score	0.101999 (rank : 175)
Query Neighborhood Hits	378	Target Neighborhood Hits	788	Shared Neighborhood Hits	132
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MKL1_MOUSE
θ value	0.279714 (rank : 155)	NC score	0.063003 (rank : 405)
Query Neighborhood Hits	378	Target Neighborhood Hits	667	Shared Neighborhood Hits	79
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

NCOA6_MOUSE
θ value	0.279714 (rank : 156)	NC score	0.118877 (rank : 106)
Query Neighborhood Hits	378	Target Neighborhood Hits	1076	Shared Neighborhood Hits	131
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

PAF49_HUMAN
θ value	0.279714 (rank : 157)	NC score	0.091265 (rank : 229)
Query Neighborhood Hits	378	Target Neighborhood Hits	169	Shared Neighborhood Hits	37
SwissProt Accessions	O15446, Q32N11, Q7Z5U2, Q9UPF6	Gene names	CD3EAP, ASE1, CAST, PAF49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (CAST).

AFF1_HUMAN
θ value	0.365318 (rank : 158)	NC score	0.097667 (rank : 198)
Query Neighborhood Hits	378	Target Neighborhood Hits	506	Shared Neighborhood Hits	86
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

FOXN1_HUMAN
θ value	0.365318 (rank : 159)	NC score	0.027383 (rank : 640)
Query Neighborhood Hits	378	Target Neighborhood Hits	377	Shared Neighborhood Hits	40
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

GRHL1_MOUSE
θ value	0.365318 (rank : 160)	NC score	0.039111 (rank : 599)
Query Neighborhood Hits	378	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	Q921D9, Q8K5C1	Gene names	Grhl1, Mgr, Tcfcp2l2
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 1 homolog (Transcription factor CP2-like 2) (Transcription factor LBP-32).

HGS_MOUSE
θ value	0.365318 (rank : 161)	NC score	0.058704 (rank : 450)
Query Neighborhood Hits	378	Target Neighborhood Hits	589	Shared Neighborhood Hits	65
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

LARP4_MOUSE
θ value	0.365318 (rank : 162)	NC score	0.062498 (rank : 414)
Query Neighborhood Hits	378	Target Neighborhood Hits	260	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

TLE6_MOUSE
θ value	0.365318 (rank : 163)	NC score	0.019140 (rank : 679)
Query Neighborhood Hits	378	Target Neighborhood Hits	178	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WVB3	Gene names	Tle6, Grg6
Domain Architecture
Description	Transducin-like enhancer protein 6 (Groucho-related protein 6).

ZO1_MOUSE
θ value	0.365318 (rank : 164)	NC score	0.030707 (rank : 627)
Query Neighborhood Hits	378	Target Neighborhood Hits	453	Shared Neighborhood Hits	53
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

BAT3_HUMAN
θ value	0.47712 (rank : 165)	NC score	0.112316 (rank : 125)
Query Neighborhood Hits	378	Target Neighborhood Hits	490	Shared Neighborhood Hits	91
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

CAC1B_MOUSE
θ value	0.47712 (rank : 166)	NC score	0.016228 (rank : 692)
Query Neighborhood Hits	378	Target Neighborhood Hits	351	Shared Neighborhood Hits	38
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CSPG5_MOUSE
θ value	0.47712 (rank : 167)	NC score	0.051163 (rank : 551)
Query Neighborhood Hits	378	Target Neighborhood Hits	211	Shared Neighborhood Hits	21
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

FGD1_MOUSE
θ value	0.47712 (rank : 168)	NC score	0.094694 (rank : 210)
Query Neighborhood Hits	378	Target Neighborhood Hits	387	Shared Neighborhood Hits	81
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD2_HUMAN
θ value	0.47712 (rank : 169)	NC score	0.044347 (rank : 580)
Query Neighborhood Hits	378	Target Neighborhood Hits	151	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

GRHL1_HUMAN
θ value	0.47712 (rank : 170)	NC score	0.039963 (rank : 595)
Query Neighborhood Hits	378	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NZI5, Q53T93, Q6NWN7, Q6NWN8, Q6NWN9, Q8NI33	Gene names	GRHL1, LBP32, MGR, TFCP2L2
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 1 homolog (Transcription factor CP2-like 2) (Transcription factor LBP-32) (NH32) (Mammalian grainyhead).

IPMK_HUMAN
θ value	0.47712 (rank : 171)	NC score	0.026615 (rank : 644)
Query Neighborhood Hits	378	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NFU5	Gene names	IPMK, IMPK
Domain Architecture	No domain graphic available
Description	Inositol polyphosphate multikinase (EC 2.7.1.151) (Inositol 1,3,4,6- tetrakisphosphate 5-kinase).

ITSN1_MOUSE
θ value	0.47712 (rank : 172)	NC score	0.035905 (rank : 616)
Query Neighborhood Hits	378	Target Neighborhood Hits	1669	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

LAD1_MOUSE
θ value	0.47712 (rank : 173)	NC score	0.088451 (rank : 246)
Query Neighborhood Hits	378	Target Neighborhood Hits	391	Shared Neighborhood Hits	62
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

MIS_MOUSE
θ value	0.47712 (rank : 174)	NC score	0.038596 (rank : 603)
Query Neighborhood Hits	378	Target Neighborhood Hits	86	Shared Neighborhood Hits	5
SwissProt Accessions	P27106	Gene names	Amh
Domain Architecture
Description	Muellerian-inhibiting factor precursor (MIS) (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance).

RHG25_MOUSE
θ value	0.47712 (rank : 175)	NC score	0.059004 (rank : 447)
Query Neighborhood Hits	378	Target Neighborhood Hits	492	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

TACC3_MOUSE
θ value	0.47712 (rank : 176)	NC score	0.029760 (rank : 632)
Query Neighborhood Hits	378	Target Neighborhood Hits	607	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

TCF7_MOUSE
θ value	0.47712 (rank : 177)	NC score	0.021021 (rank : 670)
Query Neighborhood Hits	378	Target Neighborhood Hits	277	Shared Neighborhood Hits	20
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

BCL7C_MOUSE
θ value	0.62314 (rank : 178)	NC score	0.049424 (rank : 569)
Query Neighborhood Hits	378	Target Neighborhood Hits	170	Shared Neighborhood Hits	30
SwissProt Accessions	O08664, Q99LS2	Gene names	Bcl7c
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member C (B-cell chronic lymphocytic leukemia/lymphoma 7C protein).

CEND1_HUMAN
θ value	0.62314 (rank : 179)	NC score	0.056991 (rank : 470)
Query Neighborhood Hits	378	Target Neighborhood Hits	284	Shared Neighborhood Hits	38
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

FOG1_MOUSE
θ value	0.62314 (rank : 180)	NC score	0.037478 (rank : 611)
Query Neighborhood Hits	378	Target Neighborhood Hits	1237	Shared Neighborhood Hits	129
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

JADE2_MOUSE
θ value	0.62314 (rank : 181)	NC score	0.041174 (rank : 590)
Query Neighborhood Hits	378	Target Neighborhood Hits	560	Shared Neighborhood Hits	69
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

LIPS_HUMAN
θ value	0.62314 (rank : 182)	NC score	0.078649 (rank : 302)
Query Neighborhood Hits	378	Target Neighborhood Hits	314	Shared Neighborhood Hits	72
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

PHLB1_MOUSE
θ value	0.62314 (rank : 183)	NC score	0.051985 (rank : 539)
Query Neighborhood Hits	378	Target Neighborhood Hits	678	Shared Neighborhood Hits	72
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

TBX2_HUMAN
θ value	0.62314 (rank : 184)	NC score	0.017227 (rank : 688)
Query Neighborhood Hits	378	Target Neighborhood Hits	195	Shared Neighborhood Hits	25
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

TENS1_HUMAN
θ value	0.62314 (rank : 185)	NC score	0.060982 (rank : 427)
Query Neighborhood Hits	378	Target Neighborhood Hits	400	Shared Neighborhood Hits	66
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

TPO_MOUSE
θ value	0.62314 (rank : 186)	NC score	0.038724 (rank : 602)
Query Neighborhood Hits	378	Target Neighborhood Hits	258	Shared Neighborhood Hits	23
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

TTBK1_HUMAN
θ value	0.62314 (rank : 187)	NC score	0.039397 (rank : 598)
Query Neighborhood Hits	378	Target Neighborhood Hits	1058	Shared Neighborhood Hits	88
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

CABIN_HUMAN
θ value	0.813845 (rank : 188)	NC score	0.102484 (rank : 174)
Query Neighborhood Hits	378	Target Neighborhood Hits	490	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CASC3_MOUSE
θ value	0.813845 (rank : 189)	NC score	0.070108 (rank : 354)
Query Neighborhood Hits	378	Target Neighborhood Hits	333	Shared Neighborhood Hits	51
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

COG8_MOUSE
θ value	0.813845 (rank : 190)	NC score	0.037067 (rank : 614)
Query Neighborhood Hits	378	Target Neighborhood Hits	147	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JJA2	Gene names	Cog8
Domain Architecture
Description	Conserved oligomeric Golgi complex component 8.

COKA1_HUMAN
θ value	0.813845 (rank : 191)	NC score	0.016816 (rank : 690)
Query Neighborhood Hits	378	Target Neighborhood Hits	403	Shared Neighborhood Hits	29
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

DP13A_HUMAN
θ value	0.813845 (rank : 192)	NC score	0.071731 (rank : 343)
Query Neighborhood Hits	378	Target Neighborhood Hits	107	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UKG1, Q9P2B9	Gene names	APPL1, APPL, DIP13A, KIAA1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

DP13A_MOUSE
θ value	0.813845 (rank : 193)	NC score	0.072227 (rank : 339)
Query Neighborhood Hits	378	Target Neighborhood Hits	96	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K3H0, Q3UJP7, Q69ZJ9, Q8BWZ8, Q8VCJ8, Q9CUW4	Gene names	Appl1, Dip13a, Kiaa1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

GRHL2_HUMAN
θ value	0.813845 (rank : 194)	NC score	0.037186 (rank : 612)
Query Neighborhood Hits	378	Target Neighborhood Hits	22	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ISB3, Q6NT03, Q9H8B8	Gene names	GRHL2, BOM, TFCP2L3
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 2 homolog (Brother of mammalian grainyhead) (Transcription factor CP2-like 3).

GRHL2_MOUSE
θ value	0.813845 (rank : 195)	NC score	0.037099 (rank : 613)
Query Neighborhood Hits	378	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K5C0, Q80UZ5	Gene names	Grhl2, Bom, Tcfcp2l3
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 2 homolog (Brother of mammalian grainyhead) (Transcription factor CP2-like 3).

HXB2_MOUSE
θ value	0.813845 (rank : 196)	NC score	0.006335 (rank : 725)
Query Neighborhood Hits	378	Target Neighborhood Hits	350	Shared Neighborhood Hits	16
SwissProt Accessions	P0C1T1	Gene names	Hoxb2, Hox-2.8
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-B2 (Hox-2.8).

MARK4_HUMAN
θ value	0.813845 (rank : 197)	NC score	0.030863 (rank : 625)
Query Neighborhood Hits	378	Target Neighborhood Hits	886	Shared Neighborhood Hits	44
SwissProt Accessions	Q96L34, Q8NG37, Q96JG7, Q96SQ2, Q9BYD8	Gene names	MARK4, KIAA1860, MARKL1
Domain Architecture
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1).

NEST_HUMAN
θ value	0.813845 (rank : 198)	NC score	0.032544 (rank : 620)
Query Neighborhood Hits	378	Target Neighborhood Hits	1305	Shared Neighborhood Hits	88
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

RFIP3_HUMAN
θ value	0.813845 (rank : 199)	NC score	0.038467 (rank : 605)
Query Neighborhood Hits	378	Target Neighborhood Hits	1055	Shared Neighborhood Hits	75
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

TXLNA_MOUSE
θ value	0.813845 (rank : 200)	NC score	0.023873 (rank : 659)
Query Neighborhood Hits	378	Target Neighborhood Hits	846	Shared Neighborhood Hits	41
SwissProt Accessions	Q6PAM1, Q6P1E5	Gene names	Txlna, Txln
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

ZEP2_HUMAN
θ value	0.813845 (rank : 201)	NC score	0.018609 (rank : 681)
Query Neighborhood Hits	378	Target Neighborhood Hits	937	Shared Neighborhood Hits	58
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

AAK1_HUMAN
θ value	1.06291 (rank : 202)	NC score	0.050994 (rank : 554)
Query Neighborhood Hits	378	Target Neighborhood Hits	1077	Shared Neighborhood Hits	105
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

ANR25_MOUSE
θ value	1.06291 (rank : 203)	NC score	0.036006 (rank : 615)
Query Neighborhood Hits	378	Target Neighborhood Hits	398	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

CSPG5_HUMAN
θ value	1.06291 (rank : 204)	NC score	0.055554 (rank : 486)
Query Neighborhood Hits	378	Target Neighborhood Hits	199	Shared Neighborhood Hits	28
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

FGD2_MOUSE
θ value	1.06291 (rank : 205)	NC score	0.047649 (rank : 575)
Query Neighborhood Hits	378	Target Neighborhood Hits	163	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

FOXO4_MOUSE
θ value	1.06291 (rank : 206)	NC score	0.025396 (rank : 652)
Query Neighborhood Hits	378	Target Neighborhood Hits	168	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WVH3	Gene names	Mllt7, Afx, Afx1, Fkhr3, Foxo4
Domain Architecture
Description	Fork head domain transcription factor AFX1 (Afxh) (Forkhead box protein O4).

FRAS1_MOUSE
θ value	1.06291 (rank : 207)	NC score	0.017337 (rank : 686)
Query Neighborhood Hits	378	Target Neighborhood Hits	747	Shared Neighborhood Hits	24
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

OVOL1_HUMAN
θ value	1.06291 (rank : 208)	NC score	0.002932 (rank : 738)
Query Neighborhood Hits	378	Target Neighborhood Hits	729	Shared Neighborhood Hits	24
SwissProt Accessions	O14753, Q6PCB1	Gene names	OVOL1
Domain Architecture	No domain graphic available
Description	Putative transcription factor Ovo-like 1 (hOvo1).

PLXB1_MOUSE
θ value	1.06291 (rank : 209)	NC score	0.024114 (rank : 658)
Query Neighborhood Hits	378	Target Neighborhood Hits	259	Shared Neighborhood Hits	42
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

RP3A_MOUSE
θ value	1.06291 (rank : 210)	NC score	0.049547 (rank : 568)
Query Neighborhood Hits	378	Target Neighborhood Hits	510	Shared Neighborhood Hits	75
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SASH1_MOUSE
θ value	1.06291 (rank : 211)	NC score	0.042936 (rank : 584)
Query Neighborhood Hits	378	Target Neighborhood Hits	263	Shared Neighborhood Hits	42
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

SMBT2_MOUSE
θ value	1.06291 (rank : 212)	NC score	0.017249 (rank : 687)
Query Neighborhood Hits	378	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	Q5DTW2, Q80VG7	Gene names	Sfmbt2, Kiaa1617
Domain Architecture	No domain graphic available
Description	Scm-like with four MBT domains protein 2.

ZAR1_MOUSE
θ value	1.06291 (rank : 213)	NC score	0.050020 (rank : 567)
Query Neighborhood Hits	378	Target Neighborhood Hits	254	Shared Neighborhood Hits	26
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

ZN516_HUMAN
θ value	1.06291 (rank : 214)	NC score	0.008172 (rank : 724)
Query Neighborhood Hits	378	Target Neighborhood Hits	854	Shared Neighborhood Hits	50
SwissProt Accessions	Q92618	Gene names	ZNF516, KIAA0222
Domain Architecture	No domain graphic available
Description	Zinc finger protein 516.

AAK1_MOUSE
θ value	1.38821 (rank : 215)	NC score	0.045289 (rank : 579)
Query Neighborhood Hits	378	Target Neighborhood Hits	1051	Shared Neighborhood Hits	90
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

CT174_HUMAN
θ value	1.38821 (rank : 216)	NC score	0.072720 (rank : 337)
Query Neighborhood Hits	378	Target Neighborhood Hits	181	Shared Neighborhood Hits	40
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

EDD1_HUMAN
θ value	1.38821 (rank : 217)	NC score	0.022166 (rank : 667)
Query Neighborhood Hits	378	Target Neighborhood Hits	170	Shared Neighborhood Hits	9
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

EDD1_MOUSE
θ value	1.38821 (rank : 218)	NC score	0.021004 (rank : 671)
Query Neighborhood Hits	378	Target Neighborhood Hits	167	Shared Neighborhood Hits	9
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

ERBB2_HUMAN
θ value	1.38821 (rank : 219)	NC score	0.017870 (rank : 684)
Query Neighborhood Hits	378	Target Neighborhood Hits	1073	Shared Neighborhood Hits	58
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

IRF7_HUMAN
θ value	1.38821 (rank : 220)	NC score	0.026877 (rank : 642)
Query Neighborhood Hits	378	Target Neighborhood Hits	73	Shared Neighborhood Hits	12
SwissProt Accessions	Q92985, O00331, O00332, O00333, O75924	Gene names	IRF7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

IZUM1_MOUSE
θ value	1.38821 (rank : 221)	NC score	0.026055 (rank : 646)
Query Neighborhood Hits	378	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D9J7	Gene names	Izumo1
Domain Architecture	No domain graphic available
Description	Izumo sperm-egg fusion protein 1 precursor (Sperm-specific protein izumo).

KSR1_MOUSE
θ value	1.38821 (rank : 222)	NC score	0.030403 (rank : 628)
Query Neighborhood Hits	378	Target Neighborhood Hits	870	Shared Neighborhood Hits	43
SwissProt Accessions	Q61097, Q61648, Q78DX8	Gene names	Ksr1, Ksr
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein).

MINT_MOUSE
θ value	1.38821 (rank : 223)	NC score	0.087961 (rank : 248)
Query Neighborhood Hits	378	Target Neighborhood Hits	1514	Shared Neighborhood Hits	142
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MK15_HUMAN
θ value	1.38821 (rank : 224)	NC score	0.025816 (rank : 649)
Query Neighborhood Hits	378	Target Neighborhood Hits	1038	Shared Neighborhood Hits	65
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

MNT_HUMAN
θ value	1.38821 (rank : 225)	NC score	0.128101 (rank : 89)
Query Neighborhood Hits	378	Target Neighborhood Hits	496	Shared Neighborhood Hits	97
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

OBF1_HUMAN
θ value	1.38821 (rank : 226)	NC score	0.047111 (rank : 576)
Query Neighborhood Hits	378	Target Neighborhood Hits	203	Shared Neighborhood Hits	27
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

RHG25_HUMAN
θ value	1.38821 (rank : 227)	NC score	0.050922 (rank : 555)
Query Neighborhood Hits	378	Target Neighborhood Hits	550	Shared Neighborhood Hits	43
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RP1L1_HUMAN
θ value	1.38821 (rank : 228)	NC score	0.089511 (rank : 242)
Query Neighborhood Hits	378	Target Neighborhood Hits	1072	Shared Neighborhood Hits	124
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

3BP2_MOUSE
θ value	1.81305 (rank : 229)	NC score	0.067773 (rank : 376)
Query Neighborhood Hits	378	Target Neighborhood Hits	142	Shared Neighborhood Hits	38
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

ACINU_HUMAN
θ value	1.81305 (rank : 230)	NC score	0.062593 (rank : 410)
Query Neighborhood Hits	378	Target Neighborhood Hits	828	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

CN093_HUMAN
θ value	1.81305 (rank : 231)	NC score	0.022288 (rank : 666)
Query Neighborhood Hits	378	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H972, Q86SE6, Q96CF7, Q9HA68	Gene names	C14orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf93 precursor.

FNBP2_HUMAN
θ value	1.81305 (rank : 232)	NC score	0.022074 (rank : 668)
Query Neighborhood Hits	378	Target Neighborhood Hits	432	Shared Neighborhood Hits	35
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

FRAS1_HUMAN
θ value	1.81305 (rank : 233)	NC score	0.013253 (rank : 704)
Query Neighborhood Hits	378	Target Neighborhood Hits	759	Shared Neighborhood Hits	20
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

GLI1_HUMAN
θ value	1.81305 (rank : 234)	NC score	0.004098 (rank : 735)
Query Neighborhood Hits	378	Target Neighborhood Hits	828	Shared Neighborhood Hits	45
SwissProt Accessions	P08151, Q8TDN9	Gene names	GLI1, GLI
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI).

HGS_HUMAN
θ value	1.81305 (rank : 235)	NC score	0.050143 (rank : 565)
Query Neighborhood Hits	378	Target Neighborhood Hits	517	Shared Neighborhood Hits	55
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

KCNQ1_MOUSE
θ value	1.81305 (rank : 236)	NC score	0.008718 (rank : 721)
Query Neighborhood Hits	378	Target Neighborhood Hits	175	Shared Neighborhood Hits	11
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

LMO6_MOUSE
θ value	1.81305 (rank : 237)	NC score	0.017518 (rank : 685)
Query Neighborhood Hits	378	Target Neighborhood Hits	277	Shared Neighborhood Hits	21
SwissProt Accessions	Q80VL3, Q8CAY9	Gene names	Lmo6
Domain Architecture	No domain graphic available
Description	LIM domain only protein 6 (Triple LIM domain protein 6).

NPAS4_HUMAN
θ value	1.81305 (rank : 238)	NC score	0.052188 (rank : 533)
Query Neighborhood Hits	378	Target Neighborhood Hits	214	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

NUMBL_HUMAN
θ value	1.81305 (rank : 239)	NC score	0.041633 (rank : 588)
Query Neighborhood Hits	378	Target Neighborhood Hits	394	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

OBSCN_HUMAN
θ value	1.81305 (rank : 240)	NC score	0.038456 (rank : 606)
Query Neighborhood Hits	378	Target Neighborhood Hits	1931	Shared Neighborhood Hits	126
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

PO6F1_MOUSE
θ value	1.81305 (rank : 241)	NC score	0.019576 (rank : 677)
Query Neighborhood Hits	378	Target Neighborhood Hits	581	Shared Neighborhood Hits	45
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

RECQ5_HUMAN
θ value	1.81305 (rank : 242)	NC score	0.030237 (rank : 629)
Query Neighborhood Hits	378	Target Neighborhood Hits	390	Shared Neighborhood Hits	43
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

SDC3_HUMAN
θ value	1.81305 (rank : 243)	NC score	0.092517 (rank : 220)
Query Neighborhood Hits	378	Target Neighborhood Hits	103	Shared Neighborhood Hits	43
SwissProt Accessions	O75056, Q5T1Z6, Q5T1Z7, Q96CT3, Q96PR8	Gene names	SDC3, KIAA0468
Domain Architecture
Description	Syndecan-3 (SYND3).

SMDF_HUMAN
θ value	1.81305 (rank : 244)	NC score	0.033181 (rank : 619)
Query Neighborhood Hits	378	Target Neighborhood Hits	117	Shared Neighborhood Hits	14
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

SPT5H_HUMAN
θ value	1.81305 (rank : 245)	NC score	0.076938 (rank : 316)
Query Neighborhood Hits	378	Target Neighborhood Hits	436	Shared Neighborhood Hits	72
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	1.81305 (rank : 246)	NC score	0.077541 (rank : 311)
Query Neighborhood Hits	378	Target Neighborhood Hits	437	Shared Neighborhood Hits	74
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

TBCD2_HUMAN
θ value	1.81305 (rank : 247)	NC score	0.040274 (rank : 594)
Query Neighborhood Hits	378	Target Neighborhood Hits	419	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

TPM2_HUMAN
θ value	1.81305 (rank : 248)	NC score	0.012300 (rank : 708)
Query Neighborhood Hits	378	Target Neighborhood Hits	677	Shared Neighborhood Hits	24
SwissProt Accessions	P07951, P06468, Q13894, Q53FM4, Q5TCU4, Q5TCU7, Q9UH67	Gene names	TPM2, TMSB
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

TPM2_MOUSE
θ value	1.81305 (rank : 249)	NC score	0.012117 (rank : 709)
Query Neighborhood Hits	378	Target Neighborhood Hits	676	Shared Neighborhood Hits	24
SwissProt Accessions	P58774, P02560, P46901	Gene names	Tpm2, Tpm-2
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

AIM1_HUMAN
θ value	2.36792 (rank : 250)	NC score	0.051372 (rank : 546)
Query Neighborhood Hits	378	Target Neighborhood Hits	247	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

ATBF1_MOUSE
θ value	2.36792 (rank : 251)	NC score	0.045935 (rank : 578)
Query Neighborhood Hits	378	Target Neighborhood Hits	1841	Shared Neighborhood Hits	157
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CD248_MOUSE
θ value	2.36792 (rank : 252)	NC score	0.046607 (rank : 577)
Query Neighborhood Hits	378	Target Neighborhood Hits	578	Shared Neighborhood Hits	60
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CSPG3_HUMAN
θ value	2.36792 (rank : 253)	NC score	0.018100 (rank : 682)
Query Neighborhood Hits	378	Target Neighborhood Hits	676	Shared Neighborhood Hits	55
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

IRF3_HUMAN
θ value	2.36792 (rank : 254)	NC score	0.018052 (rank : 683)
Query Neighborhood Hits	378	Target Neighborhood Hits	129	Shared Neighborhood Hits	15
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

OBF1_MOUSE
θ value	2.36792 (rank : 255)	NC score	0.038483 (rank : 604)
Query Neighborhood Hits	378	Target Neighborhood Hits	73	Shared Neighborhood Hits	14
SwissProt Accessions	Q64693	Gene names	Pou2af1, Obf-1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (BOB1) (OCA-B).

SRRM1_MOUSE
θ value	2.36792 (rank : 256)	NC score	0.178369 (rank : 36)
Query Neighborhood Hits	378	Target Neighborhood Hits	966	Shared Neighborhood Hits	153
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SSBP4_HUMAN
θ value	2.36792 (rank : 257)	NC score	0.040339 (rank : 593)
Query Neighborhood Hits	378	Target Neighborhood Hits	753	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

STAT2_HUMAN
θ value	2.36792 (rank : 258)	NC score	0.049205 (rank : 570)
Query Neighborhood Hits	378	Target Neighborhood Hits	99	Shared Neighborhood Hits	12
SwissProt Accessions	P52630, Q16430, Q16431	Gene names	STAT2
Domain Architecture
Description	Signal transducer and activator of transcription 2 (p113).

SYTL1_MOUSE
θ value	2.36792 (rank : 259)	NC score	0.028723 (rank : 638)
Query Neighborhood Hits	378	Target Neighborhood Hits	314	Shared Neighborhood Hits	38
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

UN13B_MOUSE
θ value	2.36792 (rank : 260)	NC score	0.105159 (rank : 161)
Query Neighborhood Hits	378	Target Neighborhood Hits	210	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

ZN688_HUMAN
θ value	2.36792 (rank : 261)	NC score	0.000832 (rank : 742)
Query Neighborhood Hits	378	Target Neighborhood Hits	873	Shared Neighborhood Hits	52
SwissProt Accessions	Q8WV14, O75701, Q8IW91, Q96MN0	Gene names	ZNF688
Domain Architecture	No domain graphic available
Description	Zinc finger protein 688.

AMOL1_MOUSE
θ value	3.0926 (rank : 262)	NC score	0.012392 (rank : 707)
Query Neighborhood Hits	378	Target Neighborhood Hits	445	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

BHLH3_MOUSE
θ value	3.0926 (rank : 263)	NC score	0.015458 (rank : 695)
Query Neighborhood Hits	378	Target Neighborhood Hits	70	Shared Neighborhood Hits	7
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

CAC1G_HUMAN
θ value	3.0926 (rank : 264)	NC score	0.026608 (rank : 645)
Query Neighborhood Hits	378	Target Neighborhood Hits	587	Shared Neighborhood Hits	63
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CAC1H_HUMAN
θ value	3.0926 (rank : 265)	NC score	0.024857 (rank : 654)
Query Neighborhood Hits	378	Target Neighborhood Hits	307	Shared Neighborhood Hits	41
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CENA2_HUMAN
θ value	3.0926 (rank : 266)	NC score	0.057720 (rank : 464)
Query Neighborhood Hits	378	Target Neighborhood Hits	83	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

COFA1_MOUSE
θ value	3.0926 (rank : 267)	NC score	0.040791 (rank : 592)
Query Neighborhood Hits	378	Target Neighborhood Hits	305	Shared Neighborhood Hits	51
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

DCC_MOUSE
θ value	3.0926 (rank : 268)	NC score	0.015309 (rank : 698)
Query Neighborhood Hits	378	Target Neighborhood Hits	896	Shared Neighborhood Hits	62
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

EGFL9_MOUSE
θ value	3.0926 (rank : 269)	NC score	0.005127 (rank : 731)
Query Neighborhood Hits	378	Target Neighborhood Hits	379	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

ETV4_MOUSE
θ value	3.0926 (rank : 270)	NC score	0.015335 (rank : 697)
Query Neighborhood Hits	378	Target Neighborhood Hits	100	Shared Neighborhood Hits	14
SwissProt Accessions	P28322	Gene names	Etv4, Pea-3, Pea3
Domain Architecture
Description	ETS translocation variant 4 (Polyomavirus enhancer activator 3) (Protein PEA3).

FBX43_HUMAN
θ value	3.0926 (rank : 271)	NC score	0.016398 (rank : 691)
Query Neighborhood Hits	378	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q4G163	Gene names	FBXO43, EMI2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).

KIF17_HUMAN
θ value	3.0926 (rank : 272)	NC score	0.005037 (rank : 732)
Query Neighborhood Hits	378	Target Neighborhood Hits	365	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P2E2, O95077, Q53YS6, Q5VWA9, Q6GSA8, Q8N411	Gene names	KIF17, KIAA1405, KIF3X
Domain Architecture
Description	Kinesin-like protein KIF17 (KIF3-related motor protein).

LIMD1_MOUSE
θ value	3.0926 (rank : 273)	NC score	0.029829 (rank : 630)
Query Neighborhood Hits	378	Target Neighborhood Hits	291	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QXD8, Q8C8G4, Q9CW55	Gene names	Limd1
Domain Architecture
Description	LIM domain-containing protein 1.

MA1B1_HUMAN
θ value	3.0926 (rank : 274)	NC score	0.020655 (rank : 672)
Query Neighborhood Hits	378	Target Neighborhood Hits	125	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UKM7, Q5VSG3, Q9BRS9, Q9Y5K7	Gene names	MAN1B1
Domain Architecture
Description	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific-processing alpha-mannosidase).

MARK4_MOUSE
θ value	3.0926 (rank : 275)	NC score	0.029785 (rank : 631)
Query Neighborhood Hits	378	Target Neighborhood Hits	898	Shared Neighborhood Hits	44
SwissProt Accessions	Q8CIP4, Q80T81	Gene names	Mark4, Kiaa1860
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1).

MNT_MOUSE
θ value	3.0926 (rank : 276)	NC score	0.120289 (rank : 101)
Query Neighborhood Hits	378	Target Neighborhood Hits	432	Shared Neighborhood Hits	95
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

OXRP_HUMAN
θ value	3.0926 (rank : 277)	NC score	0.025993 (rank : 648)
Query Neighborhood Hits	378	Target Neighborhood Hits	544	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

PRP17_HUMAN
θ value	3.0926 (rank : 278)	NC score	0.002378 (rank : 739)
Query Neighborhood Hits	378	Target Neighborhood Hits	297	Shared Neighborhood Hits	4
SwissProt Accessions	O60508, O75471, Q9UPG1	Gene names	CDC40, PRP17
Domain Architecture
Description	Pre-mRNA-splicing factor PRP17 (hPRP17) (Cell division cycle 40 homolog) (EH-binding protein 3) (Ehb3).

PTN22_MOUSE
θ value	3.0926 (rank : 279)	NC score	0.008388 (rank : 722)
Query Neighborhood Hits	378	Target Neighborhood Hits	179	Shared Neighborhood Hits	21
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTN23_MOUSE
θ value	3.0926 (rank : 280)	NC score	0.080089 (rank : 292)
Query Neighborhood Hits	378	Target Neighborhood Hits	726	Shared Neighborhood Hits	146
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

SH22A_HUMAN
θ value	3.0926 (rank : 281)	NC score	0.028341 (rank : 639)
Query Neighborhood Hits	378	Target Neighborhood Hits	144	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

SPEG_MOUSE
θ value	3.0926 (rank : 282)	NC score	0.055329 (rank : 491)
Query Neighborhood Hits	378	Target Neighborhood Hits	1959	Shared Neighborhood Hits	177
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TAB3_MOUSE
θ value	3.0926 (rank : 283)	NC score	0.050840 (rank : 556)
Query Neighborhood Hits	378	Target Neighborhood Hits	273	Shared Neighborhood Hits	50
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

TRIM8_MOUSE
θ value	3.0926 (rank : 284)	NC score	0.010954 (rank : 712)
Query Neighborhood Hits	378	Target Neighborhood Hits	674	Shared Neighborhood Hits	27
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

ZN286_HUMAN
θ value	3.0926 (rank : 285)	NC score	-0.000765 (rank : 745)
Query Neighborhood Hits	378	Target Neighborhood Hits	775	Shared Neighborhood Hits	29
SwissProt Accessions	Q9HBT8, Q96JF3	Gene names	ZNF286, KIAA1874
Domain Architecture
Description	Zinc finger protein 286.

BAT3_MOUSE
θ value	4.03905 (rank : 286)	NC score	0.118808 (rank : 107)
Query Neighborhood Hits	378	Target Neighborhood Hits	518	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

BMPER_MOUSE
θ value	4.03905 (rank : 287)	NC score	0.015984 (rank : 694)
Query Neighborhood Hits	378	Target Neighborhood Hits	194	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

BSN_HUMAN
θ value	4.03905 (rank : 288)	NC score	0.145174 (rank : 62)
Query Neighborhood Hits	378	Target Neighborhood Hits	1537	Shared Neighborhood Hits	178
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CSF1_HUMAN
θ value	4.03905 (rank : 289)	NC score	0.041661 (rank : 587)
Query Neighborhood Hits	378	Target Neighborhood Hits	258	Shared Neighborhood Hits	42
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

DOK1_HUMAN
θ value	4.03905 (rank : 290)	NC score	0.014704 (rank : 700)
Query Neighborhood Hits	378	Target Neighborhood Hits	85	Shared Neighborhood Hits	11
SwissProt Accessions	Q99704, O43204, Q9UHG6	Gene names	DOK1
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)) (pp62).

ETV4_HUMAN
θ value	4.03905 (rank : 291)	NC score	0.015350 (rank : 696)
Query Neighborhood Hits	378	Target Neighborhood Hits	100	Shared Neighborhood Hits	16
SwissProt Accessions	P43268, Q96AW9	Gene names	ETV4, E1AF
Domain Architecture	No domain graphic available
Description	ETS translocation variant 4 (Adenovirus E1A enhancer-binding protein) (E1A-F).

GMIP_MOUSE
θ value	4.03905 (rank : 292)	NC score	0.029566 (rank : 633)
Query Neighborhood Hits	378	Target Neighborhood Hits	202	Shared Neighborhood Hits	38
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

K1543_MOUSE
θ value	4.03905 (rank : 293)	NC score	0.085394 (rank : 264)
Query Neighborhood Hits	378	Target Neighborhood Hits	497	Shared Neighborhood Hits	77
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

OVOL1_MOUSE
θ value	4.03905 (rank : 294)	NC score	0.002164 (rank : 740)
Query Neighborhood Hits	378	Target Neighborhood Hits	716	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WTJ2, Q545S2	Gene names	Ovol1
Domain Architecture	No domain graphic available
Description	Putative transcription factor Ovo-like 1 (mOvo1) (mOvo1a).

SHAN2_MOUSE
θ value	4.03905 (rank : 295)	NC score	0.099969 (rank : 187)
Query Neighborhood Hits	378	Target Neighborhood Hits	446	Shared Neighborhood Hits	62
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SIPA1_HUMAN
θ value	4.03905 (rank : 296)	NC score	0.015066 (rank : 699)
Query Neighborhood Hits	378	Target Neighborhood Hits	250	Shared Neighborhood Hits	26
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

T22D2_HUMAN
θ value	4.03905 (rank : 297)	NC score	0.113587 (rank : 120)
Query Neighborhood Hits	378	Target Neighborhood Hits	250	Shared Neighborhood Hits	60
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

TR13B_MOUSE
θ value	4.03905 (rank : 298)	NC score	0.019900 (rank : 676)
Query Neighborhood Hits	378	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ET35, Q9DBZ3	Gene names	Tnfrsf13b, Taci
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 13B (Transmembrane activator and CAML interactor).

TRIM8_HUMAN
θ value	4.03905 (rank : 299)	NC score	0.011126 (rank : 711)
Query Neighborhood Hits	378	Target Neighborhood Hits	650	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TXLNB_MOUSE
θ value	4.03905 (rank : 300)	NC score	0.024624 (rank : 655)
Query Neighborhood Hits	378	Target Neighborhood Hits	640	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

ZEP1_MOUSE
θ value	4.03905 (rank : 301)	NC score	0.020179 (rank : 674)
Query Neighborhood Hits	378	Target Neighborhood Hits	1063	Shared Neighborhood Hits	79
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

AKAP8_HUMAN
θ value	5.27518 (rank : 302)	NC score	0.022573 (rank : 664)
Query Neighborhood Hits	378	Target Neighborhood Hits	166	Shared Neighborhood Hits	17
SwissProt Accessions	O43823	Gene names	AKAP8, AKAP95
Domain Architecture
Description	A-kinase anchor protein 8 (A-kinase anchor protein 95 kDa) (AKAP 95).

B4GT1_HUMAN
θ value	5.27518 (rank : 303)	NC score	0.008942 (rank : 717)
Query Neighborhood Hits	378	Target Neighborhood Hits	168	Shared Neighborhood Hits	13
SwissProt Accessions	P15291, Q12909, Q12910, Q12911, Q14456, Q14509, Q14523	Gene names	B4GALT1, GGTB2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

CBLB_HUMAN
θ value	5.27518 (rank : 304)	NC score	0.023670 (rank : 661)
Query Neighborhood Hits	378	Target Neighborhood Hits	261	Shared Neighborhood Hits	25
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
θ value	5.27518 (rank : 305)	NC score	0.025574 (rank : 651)
Query Neighborhood Hits	378	Target Neighborhood Hits	277	Shared Neighborhood Hits	31
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CENA1_HUMAN
θ value	5.27518 (rank : 306)	NC score	0.053087 (rank : 519)
Query Neighborhood Hits	378	Target Neighborhood Hits	87	Shared Neighborhood Hits	21
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

CK024_MOUSE
θ value	5.27518 (rank : 307)	NC score	0.091658 (rank : 226)
Query Neighborhood Hits	378	Target Neighborhood Hits	307	Shared Neighborhood Hits	48
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

CP003_HUMAN
θ value	5.27518 (rank : 308)	NC score	0.026014 (rank : 647)
Query Neighborhood Hits	378	Target Neighborhood Hits	56	Shared Neighborhood Hits	7
SwissProt Accessions	O95177, O95176	Gene names	C16orf3
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf3.

DDX51_HUMAN
θ value	5.27518 (rank : 309)	NC score	0.014391 (rank : 701)
Query Neighborhood Hits	378	Target Neighborhood Hits	332	Shared Neighborhood Hits	33
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

EP15_HUMAN
θ value	5.27518 (rank : 310)	NC score	0.009861 (rank : 715)
Query Neighborhood Hits	378	Target Neighborhood Hits	1021	Shared Neighborhood Hits	37
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

FA61A_MOUSE
θ value	5.27518 (rank : 311)	NC score	0.016916 (rank : 689)
Query Neighborhood Hits	378	Target Neighborhood Hits	81	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K2F8, Q9CTG8	Gene names	Fam61a
Domain Architecture	No domain graphic available
Description	Protein FAM61A.

FGD3_HUMAN
θ value	5.27518 (rank : 312)	NC score	0.039407 (rank : 597)
Query Neighborhood Hits	378	Target Neighborhood Hits	249	Shared Neighborhood Hits	24
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

IF2M_HUMAN
θ value	5.27518 (rank : 313)	NC score	0.013057 (rank : 705)
Query Neighborhood Hits	378	Target Neighborhood Hits	78	Shared Neighborhood Hits	4
SwissProt Accessions	P46199	Gene names	MTIF2
Domain Architecture
Description	Translation initiation factor IF-2, mitochondrial precursor (IF-2Mt) (IF-2(Mt)).

IF39_MOUSE
θ value	5.27518 (rank : 314)	NC score	0.060187 (rank : 435)
Query Neighborhood Hits	378	Target Neighborhood Hits	206	Shared Neighborhood Hits	51
SwissProt Accessions	Q8JZQ9, Q922K2	Gene names	Eif3s9
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116).

ITSN1_HUMAN
θ value	5.27518 (rank : 315)	NC score	0.030961 (rank : 624)
Query Neighborhood Hits	378	Target Neighborhood Hits	1757	Shared Neighborhood Hits	97
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN2_MOUSE
θ value	5.27518 (rank : 316)	NC score	0.024168 (rank : 657)
Query Neighborhood Hits	378	Target Neighborhood Hits	1371	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

MAGD4_HUMAN
θ value	5.27518 (rank : 317)	NC score	0.030979 (rank : 623)
Query Neighborhood Hits	378	Target Neighborhood Hits	338	Shared Neighborhood Hits	57
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

NFIP2_HUMAN
θ value	5.27518 (rank : 318)	NC score	0.018911 (rank : 680)
Query Neighborhood Hits	378	Target Neighborhood Hits	72	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NV92, Q7Z2H3, Q7Z428, Q8TAR3, Q9ULQ5	Gene names	NDFIP2, KIAA1165, N4WBP5A
Domain Architecture	No domain graphic available
Description	NEDD4 family-interacting protein 2 (NEDD4 WW domain-binding protein 5A) (Putative MAPK-activating protein PM04/PM05/PM06/PM07) (Putative NF-kappa-B-activating protein 413).

PHLB2_MOUSE
θ value	5.27518 (rank : 319)	NC score	0.023274 (rank : 663)
Query Neighborhood Hits	378	Target Neighborhood Hits	1016	Shared Neighborhood Hits	54
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PRRT3_MOUSE
θ value	5.27518 (rank : 320)	NC score	0.061252 (rank : 423)
Query Neighborhood Hits	378	Target Neighborhood Hits	162	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PE13	Gene names	Prrt3
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SCAP_HUMAN
θ value	5.27518 (rank : 321)	NC score	0.010205 (rank : 714)
Query Neighborhood Hits	378	Target Neighborhood Hits	368	Shared Neighborhood Hits	17
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

SOX13_MOUSE
θ value	5.27518 (rank : 322)	NC score	0.025034 (rank : 653)
Query Neighborhood Hits	378	Target Neighborhood Hits	495	Shared Neighborhood Hits	53
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

SRRM2_MOUSE
θ value	5.27518 (rank : 323)	NC score	0.124957 (rank : 96)
Query Neighborhood Hits	378	Target Neighborhood Hits	1470	Shared Neighborhood Hits	169
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TARA_MOUSE
θ value	5.27518 (rank : 324)	NC score	0.068938 (rank : 363)
Query Neighborhood Hits	378	Target Neighborhood Hits	1133	Shared Neighborhood Hits	120
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TAU_HUMAN
θ value	5.27518 (rank : 325)	NC score	0.083121 (rank : 280)
Query Neighborhood Hits	378	Target Neighborhood Hits	448	Shared Neighborhood Hits	82
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TXND2_HUMAN
θ value	5.27518 (rank : 326)	NC score	0.086309 (rank : 259)
Query Neighborhood Hits	378	Target Neighborhood Hits	793	Shared Neighborhood Hits	90
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

UN13B_HUMAN
θ value	5.27518 (rank : 327)	NC score	0.109900 (rank : 135)
Query Neighborhood Hits	378	Target Neighborhood Hits	217	Shared Neighborhood Hits	42
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

ZN217_HUMAN
θ value	5.27518 (rank : 328)	NC score	0.004473 (rank : 734)
Query Neighborhood Hits	378	Target Neighborhood Hits	905	Shared Neighborhood Hits	49
SwissProt Accessions	O75362	Gene names	ZNF217, ZABC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 217.

ZN358_HUMAN
θ value	5.27518 (rank : 329)	NC score	0.005580 (rank : 729)
Query Neighborhood Hits	378	Target Neighborhood Hits	840	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NW07, Q9BTM7	Gene names	ZNF358
Domain Architecture
Description	Zinc finger protein 358.

ACE_HUMAN
θ value	6.88961 (rank : 330)	NC score	0.005746 (rank : 728)
Query Neighborhood Hits	378	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	P12821, Q53YX9, Q59GY8	Gene names	ACE, DCP, DCP1
Domain Architecture
Description	Angiotensin-converting enzyme, somatic isoform precursor (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD143 antigen) [Contains: Angiotensin-converting enzyme, somatic isoform, soluble form].

ACINU_MOUSE
θ value	6.88961 (rank : 331)	NC score	0.075038 (rank : 325)
Query Neighborhood Hits	378	Target Neighborhood Hits	712	Shared Neighborhood Hits	78
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ADRB2_MOUSE
θ value	6.88961 (rank : 332)	NC score	-0.007616 (rank : 747)
Query Neighborhood Hits	378	Target Neighborhood Hits	923	Shared Neighborhood Hits	3
SwissProt Accessions	P18762	Gene names	Adrb2, Adrb2r
Domain Architecture
Description	Beta-2 adrenergic receptor (Beta-2 adrenoceptor) (Beta-2 adrenoreceptor).

BRD8_MOUSE
θ value	6.88961 (rank : 333)	NC score	0.052253 (rank : 530)
Query Neighborhood Hits	378	Target Neighborhood Hits	422	Shared Neighborhood Hits	55
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

CBP_MOUSE
θ value	6.88961 (rank : 334)	NC score	0.104472 (rank : 168)
Query Neighborhood Hits	378	Target Neighborhood Hits	1051	Shared Neighborhood Hits	145
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CENA2_MOUSE
θ value	6.88961 (rank : 335)	NC score	0.048379 (rank : 573)
Query Neighborhood Hits	378	Target Neighborhood Hits	68	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

DAF2_MOUSE
θ value	6.88961 (rank : 336)	NC score	0.008306 (rank : 723)
Query Neighborhood Hits	378	Target Neighborhood Hits	114	Shared Neighborhood Hits	15
SwissProt Accessions	Q61476	Gene names	Cd55b, Daf2
Domain Architecture
Description	Complement decay-accelerating factor transmembrane isoform precursor (DAF-TM) (CD55 antigen).

DNER_HUMAN
θ value	6.88961 (rank : 337)	NC score	0.004475 (rank : 733)
Query Neighborhood Hits	378	Target Neighborhood Hits	460	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

EGR4_HUMAN
θ value	6.88961 (rank : 338)	NC score	0.002117 (rank : 741)
Query Neighborhood Hits	378	Target Neighborhood Hits	939	Shared Neighborhood Hits	46
SwissProt Accessions	Q05215	Gene names	EGR4
Domain Architecture
Description	Early growth response protein 4 (EGR-4) (AT133).

ELK4_HUMAN
θ value	6.88961 (rank : 339)	NC score	0.023658 (rank : 662)
Query Neighborhood Hits	378	Target Neighborhood Hits	184	Shared Neighborhood Hits	30
SwissProt Accessions	P28324, P28323	Gene names	ELK4, SAP1
Domain Architecture
Description	ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1).

FOXH1_HUMAN
θ value	6.88961 (rank : 340)	NC score	0.011459 (rank : 710)
Query Neighborhood Hits	378	Target Neighborhood Hits	258	Shared Neighborhood Hits	21
SwissProt Accessions	O75593	Gene names	FOXH1, FAST1, FAST2
Domain Architecture
Description	Forkhead box protein H1 (Forkhead activin signal transducer 1) (Fast- 1) (hFAST-1) (Forkhead activin signal transducer 2) (Fast-2).

IF2M_MOUSE
θ value	6.88961 (rank : 341)	NC score	0.013262 (rank : 703)
Query Neighborhood Hits	378	Target Neighborhood Hits	183	Shared Neighborhood Hits	9
SwissProt Accessions	Q91YJ5	Gene names	Mtif2
Domain Architecture
Description	Translation initiation factor IF-2, mitochondrial precursor (IF-2Mt) (IF-2(Mt)).

LARP1_HUMAN
θ value	6.88961 (rank : 342)	NC score	0.034870 (rank : 617)
Query Neighborhood Hits	378	Target Neighborhood Hits	242	Shared Neighborhood Hits	29
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

MYO9B_HUMAN
θ value	6.88961 (rank : 343)	NC score	0.059908 (rank : 438)
Query Neighborhood Hits	378	Target Neighborhood Hits	641	Shared Neighborhood Hits	98
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYO9B_MOUSE
θ value	6.88961 (rank : 344)	NC score	0.048672 (rank : 571)
Query Neighborhood Hits	378	Target Neighborhood Hits	311	Shared Neighborhood Hits	59
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

NID2_HUMAN
θ value	6.88961 (rank : 345)	NC score	0.006270 (rank : 726)
Query Neighborhood Hits	378	Target Neighborhood Hits	456	Shared Neighborhood Hits	30
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

POLS_MOUSE
θ value	6.88961 (rank : 346)	NC score	0.016111 (rank : 693)
Query Neighborhood Hits	378	Target Neighborhood Hits	91	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PB75	Gene names	Pols
Domain Architecture	No domain graphic available
Description	DNA polymerase sigma (EC 2.7.7.7).

PRGC2_HUMAN
θ value	6.88961 (rank : 347)	NC score	0.039563 (rank : 596)
Query Neighborhood Hits	378	Target Neighborhood Hits	272	Shared Neighborhood Hits	36
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

RTBDN_MOUSE
θ value	6.88961 (rank : 348)	NC score	0.013448 (rank : 702)
Query Neighborhood Hits	378	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q8QZY4, Q6T898	Gene names	Rtbdn
Domain Architecture	No domain graphic available
Description	Retbindin precursor.

RTKN_HUMAN
θ value	6.88961 (rank : 349)	NC score	0.022455 (rank : 665)
Query Neighborhood Hits	378	Target Neighborhood Hits	97	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BST9, Q8WVN1, Q96PT6, Q9HB05	Gene names	RTKN
Domain Architecture	No domain graphic available
Description	Rhotekin.

TSSK1_HUMAN
θ value	6.88961 (rank : 350)	NC score	0.029050 (rank : 635)
Query Neighborhood Hits	378	Target Neighborhood Hits	840	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BXA7	Gene names	TSSK1, SPOGA1, SPOGA4, STK22A, STK22D
Domain Architecture
Description	Testis-specific serine/threonine-protein kinase 1 (EC 2.7.11.1) (TSSK- 1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A).

UB7I1_MOUSE
θ value	6.88961 (rank : 351)	NC score	0.021712 (rank : 669)
Query Neighborhood Hits	378	Target Neighborhood Hits	206	Shared Neighborhood Hits	31
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

VWF_MOUSE
θ value	6.88961 (rank : 352)	NC score	0.012941 (rank : 706)
Query Neighborhood Hits	378	Target Neighborhood Hits	381	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ZN206_HUMAN
θ value	6.88961 (rank : 353)	NC score	0.000257 (rank : 743)
Query Neighborhood Hits	378	Target Neighborhood Hits	853	Shared Neighborhood Hits	53
SwissProt Accessions	Q96SZ4	Gene names	ZNF206, ZSCAN10
Domain Architecture	No domain graphic available
Description	Zinc finger protein 206 (Zinc finger and SCAN domain-containing protein 10).

ZN710_HUMAN
θ value	6.88961 (rank : 354)	NC score	-0.000634 (rank : 744)
Query Neighborhood Hits	378	Target Neighborhood Hits	796	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N1W2, Q6ZMK9, Q8NDU0	Gene names	ZNF710
Domain Architecture	No domain graphic available
Description	Zinc finger protein 710.

ZNF8_HUMAN
θ value	6.88961 (rank : 355)	NC score	-0.001954 (rank : 746)
Query Neighborhood Hits	378	Target Neighborhood Hits	748	Shared Neighborhood Hits	27
SwissProt Accessions	P17098, Q6PI99	Gene names	ZNF8
Domain Architecture	No domain graphic available
Description	Zinc finger protein 8 (Zinc finger protein HF.18).

AAKG3_MOUSE
θ value	8.99809 (rank : 356)	NC score	0.005244 (rank : 730)
Query Neighborhood Hits	378	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGM7, Q80WK8, Q8CJ41	Gene names	Prkag3
Domain Architecture	No domain graphic available
Description	5'-AMP-activated protein kinase subunit gamma-3 (AMPK gamma-3 chain) (AMPK gamma3).

ATX7_HUMAN
θ value	8.99809 (rank : 357)	NC score	0.044317 (rank : 581)
Query Neighborhood Hits	378	Target Neighborhood Hits	351	Shared Neighborhood Hits	57
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

BAG3_HUMAN
θ value	8.99809 (rank : 358)	NC score	0.105758 (rank : 157)
Query Neighborhood Hits	378	Target Neighborhood Hits	314	Shared Neighborhood Hits	78
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

CABYR_MOUSE
θ value	8.99809 (rank : 359)	NC score	0.026827 (rank : 643)
Query Neighborhood Hits	378	Target Neighborhood Hits	80	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D424, Q91Y41, Q91Y42	Gene names	Cabyr, Cbp86
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86).

CD008_HUMAN
θ value	8.99809 (rank : 360)	NC score	0.024455 (rank : 656)
Query Neighborhood Hits	378	Target Neighborhood Hits	330	Shared Neighborhood Hits	32
SwissProt Accessions	P78312, O43607, P78311, P78313, Q9UEG8	Gene names	C4orf8
Domain Architecture	No domain graphic available
Description	Protein C4orf8 (Protein IT14).

HCLS1_HUMAN
θ value	8.99809 (rank : 361)	NC score	0.038236 (rank : 608)
Query Neighborhood Hits	378	Target Neighborhood Hits	358	Shared Neighborhood Hits	45
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

JIP1_HUMAN
θ value	8.99809 (rank : 362)	NC score	0.023827 (rank : 660)
Query Neighborhood Hits	378	Target Neighborhood Hits	271	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

KPCG_HUMAN
θ value	8.99809 (rank : 363)	NC score	0.078275 (rank : 304)
Query Neighborhood Hits	378	Target Neighborhood Hits	1126	Shared Neighborhood Hits	64
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCG_MOUSE
θ value	8.99809 (rank : 364)	NC score	0.078110 (rank : 307)
Query Neighborhood Hits	378	Target Neighborhood Hits	1123	Shared Neighborhood Hits	64
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

LAD1_HUMAN
θ value	8.99809 (rank : 365)	NC score	0.068419 (rank : 366)
Query Neighborhood Hits	378	Target Neighborhood Hits	441	Shared Neighborhood Hits	51
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

MAP4_HUMAN
θ value	8.99809 (rank : 366)	NC score	0.097474 (rank : 199)
Query Neighborhood Hits	378	Target Neighborhood Hits	428	Shared Neighborhood Hits	73
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MBTP1_HUMAN
θ value	8.99809 (rank : 367)	NC score	0.008803 (rank : 718)
Query Neighborhood Hits	378	Target Neighborhood Hits	28	Shared Neighborhood Hits	6
SwissProt Accessions	Q14703, Q9UF67	Gene names	MBTPS1, KIAA0091, S1P, SKI1
Domain Architecture	No domain graphic available
Description	Membrane-bound transcription factor site 1 protease precursor (EC 3.4.21.-) (S1P endopeptidase) (Site-1 protease) (Subtilisin/kexin- isozyme 1) (SKI-1).

MEF2B_MOUSE
θ value	8.99809 (rank : 368)	NC score	0.020233 (rank : 673)
Query Neighborhood Hits	378	Target Neighborhood Hits	218	Shared Neighborhood Hits	20
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

MINT_HUMAN
θ value	8.99809 (rank : 369)	NC score	0.093055 (rank : 216)
Query Neighborhood Hits	378	Target Neighborhood Hits	1291	Shared Neighborhood Hits	141
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NFAC2_HUMAN
θ value	8.99809 (rank : 370)	NC score	0.019474 (rank : 678)
Query Neighborhood Hits	378	Target Neighborhood Hits	101	Shared Neighborhood Hits	25
SwissProt Accessions	Q13469, Q13468, Q5TFW7, Q5TFW8, Q9NPX6, Q9NQH3, Q9UJR2	Gene names	NFATC2, NFAT1, NFATP
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).

PGM2L_MOUSE
θ value	8.99809 (rank : 371)	NC score	0.005771 (rank : 727)
Query Neighborhood Hits	378	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CAA7	Gene names	Pgm2l1
Domain Architecture	No domain graphic available
Description	Phosphoglucomutase-2-like 1 (EC 5.4.2.2).

PHLB2_HUMAN
θ value	8.99809 (rank : 372)	NC score	0.019939 (rank : 675)
Query Neighborhood Hits	378	Target Neighborhood Hits	964	Shared Neighborhood Hits	47
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PKHA2_HUMAN
θ value	8.99809 (rank : 373)	NC score	0.088786 (rank : 244)
Query Neighborhood Hits	378	Target Neighborhood Hits	119	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

SIG10_HUMAN
θ value	8.99809 (rank : 374)	NC score	0.003694 (rank : 737)
Query Neighborhood Hits	378	Target Neighborhood Hits	363	Shared Neighborhood Hits	22
SwissProt Accessions	Q96LC7, Q6UXI8, Q96G54, Q96LC8	Gene names	SIGLEC10, SLG2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 10 precursor (Siglec-10) (Siglec- like protein 2).

STAB2_MOUSE
θ value	8.99809 (rank : 375)	NC score	0.003773 (rank : 736)
Query Neighborhood Hits	378	Target Neighborhood Hits	528	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

SVIL_MOUSE
θ value	8.99809 (rank : 376)	NC score	0.031194 (rank : 622)
Query Neighborhood Hits	378	Target Neighborhood Hits	439	Shared Neighborhood Hits	53
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

TNFC_MOUSE
θ value	8.99809 (rank : 377)	NC score	0.008803 (rank : 719)
Query Neighborhood Hits	378	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P41155	Gene names	Ltb, Tnfc, Tnfsf3
Domain Architecture
Description	Lymphotoxin-beta (LT-beta) (Tumor necrosis factor C) (TNF-C) (Tumor necrosis factor ligand superfamily member 3).

ZCH11_HUMAN
θ value	8.99809 (rank : 378)	NC score	0.026948 (rank : 641)
Query Neighborhood Hits	378	Target Neighborhood Hits	278	Shared Neighborhood Hits	28
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

3BP1_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.090843 (rank : 231)
Query Neighborhood Hits	378	Target Neighborhood Hits	376	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

3BP1_MOUSE
θ value	θ > 10 (rank : 380)	NC score	0.060774 (rank : 429)
Query Neighborhood Hits	378	Target Neighborhood Hits	238	Shared Neighborhood Hits	69
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

3BP2_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.061182 (rank : 424)
Query Neighborhood Hits	378	Target Neighborhood Hits	296	Shared Neighborhood Hits	52
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

AB1IP_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.066865 (rank : 380)
Query Neighborhood Hits	378	Target Neighborhood Hits	213	Shared Neighborhood Hits	66
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

AB1IP_MOUSE
θ value	θ > 10 (rank : 383)	NC score	0.059375 (rank : 442)
Query Neighborhood Hits	378	Target Neighborhood Hits	181	Shared Neighborhood Hits	61
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

ABI2_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.050156 (rank : 564)
Query Neighborhood Hits	378	Target Neighborhood Hits	350	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

AFF1_MOUSE
θ value	θ > 10 (rank : 385)	NC score	0.073669 (rank : 329)
Query Neighborhood Hits	378	Target Neighborhood Hits	351	Shared Neighborhood Hits	73
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

ALEX_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.129763 (rank : 86)
Query Neighborhood Hits	378	Target Neighborhood Hits	361	Shared Neighborhood Hits	95
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ALEX_MOUSE
θ value	θ > 10 (rank : 387)	NC score	0.097132 (rank : 201)
Query Neighborhood Hits	378	Target Neighborhood Hits	197	Shared Neighborhood Hits	65
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

AMELX_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.053569 (rank : 512)
Query Neighborhood Hits	378	Target Neighborhood Hits	95	Shared Neighborhood Hits	33
SwissProt Accessions	Q99217, Q96NW6, Q9UCA7	Gene names	AMELX, AMG, AMGX
Domain Architecture
Description	Amelogenin, X isoform precursor.

AMOT_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.061262 (rank : 422)
Query Neighborhood Hits	378	Target Neighborhood Hits	712	Shared Neighborhood Hits	84
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

AMPH_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.076938 (rank : 315)
Query Neighborhood Hits	378	Target Neighborhood Hits	291	Shared Neighborhood Hits	55
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

AP180_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.066215 (rank : 388)
Query Neighborhood Hits	378	Target Neighborhood Hits	183	Shared Neighborhood Hits	49
SwissProt Accessions	O60641, Q5JX13, Q68DL9, Q6P9D3, Q9NTY7	Gene names	SNAP91, KIAA0656
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein).

AP180_MOUSE
θ value	θ > 10 (rank : 392)	NC score	0.068196 (rank : 371)
Query Neighborhood Hits	378	Target Neighborhood Hits	194	Shared Neighborhood Hits	47
SwissProt Accessions	Q61548, Q61547	Gene names	Snap91
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein) (Phosphoprotein F1- 20).

ARHGF_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.073619 (rank : 330)
Query Neighborhood Hits	378	Target Neighborhood Hits	214	Shared Neighborhood Hits	75
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

ARI1A_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.084052 (rank : 269)
Query Neighborhood Hits	378	Target Neighborhood Hits	787	Shared Neighborhood Hits	113
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

ARI1B_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.055676 (rank : 485)
Query Neighborhood Hits	378	Target Neighborhood Hits	567	Shared Neighborhood Hits	87
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

ARID2_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.050043 (rank : 566)
Query Neighborhood Hits	378	Target Neighborhood Hits	302	Shared Neighborhood Hits	45
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

ASPP2_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.066248 (rank : 387)
Query Neighborhood Hits	378	Target Neighborhood Hits	1156	Shared Neighborhood Hits	84
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

ATN1_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.140044 (rank : 69)
Query Neighborhood Hits	378	Target Neighborhood Hits	676	Shared Neighborhood Hits	139
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

ATX2L_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.079008 (rank : 297)
Query Neighborhood Hits	378	Target Neighborhood Hits	443	Shared Neighborhood Hits	87
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

ATX2L_MOUSE
θ value	θ > 10 (rank : 400)	NC score	0.060619 (rank : 430)
Query Neighborhood Hits	378	Target Neighborhood Hits	401	Shared Neighborhood Hits	74
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

ATX2_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.073749 (rank : 328)
Query Neighborhood Hits	378	Target Neighborhood Hits	375	Shared Neighborhood Hits	81
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

ATX2_MOUSE
θ value	θ > 10 (rank : 402)	NC score	0.065191 (rank : 393)
Query Neighborhood Hits	378	Target Neighborhood Hits	445	Shared Neighborhood Hits	81
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

AUTS2_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.090282 (rank : 235)
Query Neighborhood Hits	378	Target Neighborhood Hits	342	Shared Neighborhood Hits	98
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

BASP_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.139865 (rank : 70)
Query Neighborhood Hits	378	Target Neighborhood Hits	321	Shared Neighborhood Hits	75
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BASP_MOUSE
θ value	θ > 10 (rank : 405)	NC score	0.166365 (rank : 40)
Query Neighborhood Hits	378	Target Neighborhood Hits	260	Shared Neighborhood Hits	67
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BAT2_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.132674 (rank : 82)
Query Neighborhood Hits	378	Target Neighborhood Hits	931	Shared Neighborhood Hits	162
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAT2_MOUSE
θ value	θ > 10 (rank : 407)	NC score	0.109437 (rank : 138)
Query Neighborhood Hits	378	Target Neighborhood Hits	947	Shared Neighborhood Hits	165
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BCL9_MOUSE
θ value	θ > 10 (rank : 408)	NC score	0.101572 (rank : 177)
Query Neighborhood Hits	378	Target Neighborhood Hits	770	Shared Neighborhood Hits	110
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

BIN1_MOUSE
θ value	θ > 10 (rank : 409)	NC score	0.053771 (rank : 508)
Query Neighborhood Hits	378	Target Neighborhood Hits	283	Shared Neighborhood Hits	32
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

BORG5_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.058296 (rank : 454)
Query Neighborhood Hits	378	Target Neighborhood Hits	135	Shared Neighborhood Hits	48
SwissProt Accessions	Q00587, Q96GN1	Gene names	CDC42EP1, BORG5, CEP1, MSE55
Domain Architecture
Description	Cdc42 effector protein 1 (Binder of Rho GTPases 5) (Serum protein MSE55).

BPTF_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.058440 (rank : 453)
Query Neighborhood Hits	378	Target Neighborhood Hits	786	Shared Neighborhood Hits	78
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BRD4_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.095526 (rank : 207)
Query Neighborhood Hits	378	Target Neighborhood Hits	851	Shared Neighborhood Hits	146
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

BRD4_MOUSE
θ value	θ > 10 (rank : 413)	NC score	0.108406 (rank : 145)
Query Neighborhood Hits	378	Target Neighborhood Hits	845	Shared Neighborhood Hits	139
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CASC3_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.052088 (rank : 536)
Query Neighborhood Hits	378	Target Neighborhood Hits	204	Shared Neighborhood Hits	41
SwissProt Accessions	O15234	Gene names	CASC3, MLN51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein) (Metastatic lymph node protein 51) (Protein MLN 51) (Protein barentsz) (Btz).

CBP_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.111675 (rank : 128)
Query Neighborhood Hits	378	Target Neighborhood Hits	941	Shared Neighborhood Hits	159
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CCNK_MOUSE
θ value	θ > 10 (rank : 416)	NC score	0.128166 (rank : 88)
Query Neighborhood Hits	378	Target Neighborhood Hits	350	Shared Neighborhood Hits	110
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CDN1C_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.197968 (rank : 23)
Query Neighborhood Hits	378	Target Neighborhood Hits	168	Shared Neighborhood Hits	85
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CEND3_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.056216 (rank : 482)
Query Neighborhood Hits	378	Target Neighborhood Hits	275	Shared Neighborhood Hits	62
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CEND3_MOUSE
θ value	θ > 10 (rank : 419)	NC score	0.058145 (rank : 456)
Query Neighborhood Hits	378	Target Neighborhood Hits	228	Shared Neighborhood Hits	46
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CEND_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.053098 (rank : 518)
Query Neighborhood Hits	378	Target Neighborhood Hits	84	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N111, Q9NYM6	Gene names	CEND1, BM88
Domain Architecture	No domain graphic available
Description	Cell cycle exit and neuronal differentiation protein 1 (BM88 antigen).

CG1_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.055216 (rank : 494)
Query Neighborhood Hits	378	Target Neighborhood Hits	222	Shared Neighborhood Hits	45
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

CHIN_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.097339 (rank : 200)
Query Neighborhood Hits	378	Target Neighborhood Hits	227	Shared Neighborhood Hits	39
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIN_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.094151 (rank : 211)
Query Neighborhood Hits	378	Target Neighborhood Hits	229	Shared Neighborhood Hits	40
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIO_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.098432 (rank : 194)
Query Neighborhood Hits	378	Target Neighborhood Hits	220	Shared Neighborhood Hits	41
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CHIO_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.101421 (rank : 178)
Query Neighborhood Hits	378	Target Neighborhood Hits	130	Shared Neighborhood Hits	38
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CI079_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.053027 (rank : 522)
Query Neighborhood Hits	378	Target Neighborhood Hits	288	Shared Neighborhood Hits	52
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

CIC_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.100837 (rank : 179)
Query Neighborhood Hits	378	Target Neighborhood Hits	992	Shared Neighborhood Hits	146
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CIC_MOUSE
θ value	θ > 10 (rank : 428)	NC score	0.094768 (rank : 209)
Query Neighborhood Hits	378	Target Neighborhood Hits	742	Shared Neighborhood Hits	136
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CITE4_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.056683 (rank : 475)
Query Neighborhood Hits	378	Target Neighborhood Hits	67	Shared Neighborhood Hits	21
SwissProt Accessions	Q96RK1	Gene names	CITED4, MRG2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

CIZ1_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.099254 (rank : 189)
Query Neighborhood Hits	378	Target Neighborhood Hits	359	Shared Neighborhood Hits	70
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

CJ047_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.054237 (rank : 503)
Query Neighborhood Hits	378	Target Neighborhood Hits	164	Shared Neighborhood Hits	41
SwissProt Accessions	Q86WR7, Q5W0J9, Q5W0K0, Q5W0K1, Q5W0K2, Q6PJC8, Q8N317	Gene names	C10orf47
Domain Architecture	No domain graphic available
Description	Protein C10orf47.

CJ078_MOUSE
θ value	θ > 10 (rank : 432)	NC score	0.182883 (rank : 30)
Query Neighborhood Hits	378	Target Neighborhood Hits	559	Shared Neighborhood Hits	121
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CN032_HUMAN
θ value	θ > 10 (rank : 433)	NC score	0.140698 (rank : 67)
Query Neighborhood Hits	378	Target Neighborhood Hits	267	Shared Neighborhood Hits	77
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CN032_MOUSE
θ value	θ > 10 (rank : 434)	NC score	0.141696 (rank : 66)
Query Neighborhood Hits	378	Target Neighborhood Hits	233	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CN155_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.182119 (rank : 32)
Query Neighborhood Hits	378	Target Neighborhood Hits	385	Shared Neighborhood Hits	108
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CNKR1_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.050473 (rank : 562)
Query Neighborhood Hits	378	Target Neighborhood Hits	154	Shared Neighborhood Hits	31
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

CNOT3_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.093796 (rank : 212)
Query Neighborhood Hits	378	Target Neighborhood Hits	425	Shared Neighborhood Hits	74
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CNOT3_MOUSE
θ value	θ > 10 (rank : 438)	NC score	0.071103 (rank : 347)
Query Neighborhood Hits	378	Target Neighborhood Hits	504	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CO002_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.053646 (rank : 509)
Query Neighborhood Hits	378	Target Neighborhood Hits	387	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

CO039_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.108683 (rank : 143)
Query Neighborhood Hits	378	Target Neighborhood Hits	264	Shared Neighborhood Hits	71
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

CO1A1_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.051990 (rank : 538)
Query Neighborhood Hits	378	Target Neighborhood Hits	475	Shared Neighborhood Hits	81
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO1A1_MOUSE
θ value	θ > 10 (rank : 442)	NC score	0.053049 (rank : 520)
Query Neighborhood Hits	378	Target Neighborhood Hits	457	Shared Neighborhood Hits	78
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO3A1_HUMAN
θ value	θ > 10 (rank : 443)	NC score	0.050748 (rank : 557)
Query Neighborhood Hits	378	Target Neighborhood Hits	452	Shared Neighborhood Hits	75
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO3A1_MOUSE
θ value	θ > 10 (rank : 444)	NC score	0.052350 (rank : 529)
Query Neighborhood Hits	378	Target Neighborhood Hits	466	Shared Neighborhood Hits	78
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO4A5_HUMAN
θ value	θ > 10 (rank : 445)	NC score	0.053032 (rank : 521)
Query Neighborhood Hits	378	Target Neighborhood Hits	383	Shared Neighborhood Hits	65
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

COHA1_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.051150 (rank : 552)
Query Neighborhood Hits	378	Target Neighborhood Hits	400	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

COIA1_HUMAN
θ value	θ > 10 (rank : 447)	NC score	0.052351 (rank : 528)
Query Neighborhood Hits	378	Target Neighborhood Hits	447	Shared Neighborhood Hits	77
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CPSF6_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.114795 (rank : 117)
Query Neighborhood Hits	378	Target Neighborhood Hits	359	Shared Neighborhood Hits	87
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.116698 (rank : 111)
Query Neighborhood Hits	378	Target Neighborhood Hits	356	Shared Neighborhood Hits	86
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CRSP2_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.055112 (rank : 496)
Query Neighborhood Hits	378	Target Neighborhood Hits	380	Shared Neighborhood Hits	65
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

CRTC1_HUMAN
θ value	θ > 10 (rank : 451)	NC score	0.085146 (rank : 265)
Query Neighborhood Hits	378	Target Neighborhood Hits	319	Shared Neighborhood Hits	72
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

CRTC1_MOUSE
θ value	θ > 10 (rank : 452)	NC score	0.064298 (rank : 400)
Query Neighborhood Hits	378	Target Neighborhood Hits	230	Shared Neighborhood Hits	52
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

CS007_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.069161 (rank : 360)
Query Neighborhood Hits	378	Target Neighborhood Hits	401	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

CS007_MOUSE
θ value	θ > 10 (rank : 454)	NC score	0.081998 (rank : 284)
Query Neighborhood Hits	378	Target Neighborhood Hits	464	Shared Neighborhood Hits	87
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

CS016_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.139036 (rank : 72)
Query Neighborhood Hits	378	Target Neighborhood Hits	310	Shared Neighborhood Hits	86
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

CSKI1_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.091953 (rank : 225)
Query Neighborhood Hits	378	Target Neighborhood Hits	997	Shared Neighborhood Hits	149
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI1_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.084773 (rank : 266)
Query Neighborhood Hits	378	Target Neighborhood Hits	1031	Shared Neighborhood Hits	145
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI2_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.072175 (rank : 340)
Query Neighborhood Hits	378	Target Neighborhood Hits	747	Shared Neighborhood Hits	139
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CSKI2_MOUSE
θ value	θ > 10 (rank : 459)	NC score	0.058639 (rank : 452)
Query Neighborhood Hits	378	Target Neighborhood Hits	812	Shared Neighborhood Hits	105
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CT151_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.066855 (rank : 381)
Query Neighborhood Hits	378	Target Neighborhood Hits	382	Shared Neighborhood Hits	55
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

CTDP1_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.059163 (rank : 443)
Query Neighborhood Hits	378	Target Neighborhood Hits	416	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

DDEF1_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.053612 (rank : 510)
Query Neighborhood Hits	378	Target Neighborhood Hits	592	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DDEF2_HUMAN
θ value	θ > 10 (rank : 463)	NC score	0.061131 (rank : 425)
Query Neighborhood Hits	378	Target Neighborhood Hits	599	Shared Neighborhood Hits	89
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	θ > 10 (rank : 464)	NC score	0.057980 (rank : 458)
Query Neighborhood Hits	378	Target Neighborhood Hits	625	Shared Neighborhood Hits	82
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DIAP1_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.073139 (rank : 332)
Query Neighborhood Hits	378	Target Neighborhood Hits	784	Shared Neighborhood Hits	108
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

DIAP1_MOUSE
θ value	θ > 10 (rank : 466)	NC score	0.068373 (rank : 368)
Query Neighborhood Hits	378	Target Neighborhood Hits	839	Shared Neighborhood Hits	90
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

DOT1L_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.057533 (rank : 465)
Query Neighborhood Hits	378	Target Neighborhood Hits	660	Shared Neighborhood Hits	76
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

EFS_MOUSE
θ value	θ > 10 (rank : 468)	NC score	0.053517 (rank : 513)
Query Neighborhood Hits	378	Target Neighborhood Hits	389	Shared Neighborhood Hits	55
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

ELN_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.051389 (rank : 545)
Query Neighborhood Hits	378	Target Neighborhood Hits	85	Shared Neighborhood Hits	11
SwissProt Accessions	P15502, O15336, O15337, Q14233, Q14234, Q14235, Q14238, Q6P0L4, Q6ZWJ6, Q75MU5, Q7Z316, Q7Z3F5, Q9UMF5	Gene names	ELN
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

ENAH_HUMAN
θ value	θ > 10 (rank : 470)	NC score	0.070968 (rank : 348)
Query Neighborhood Hits	378	Target Neighborhood Hits	784	Shared Neighborhood Hits	106
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

ENAH_MOUSE
θ value	θ > 10 (rank : 471)	NC score	0.150508 (rank : 55)
Query Neighborhood Hits	378	Target Neighborhood Hits	919	Shared Neighborhood Hits	170
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

ENL_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.066999 (rank : 379)
Query Neighborhood Hits	378	Target Neighborhood Hits	305	Shared Neighborhood Hits	54
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

EP300_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.113435 (rank : 121)
Query Neighborhood Hits	378	Target Neighborhood Hits	821	Shared Neighborhood Hits	150
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

EP400_HUMAN
θ value	θ > 10 (rank : 474)	NC score	0.060495 (rank : 432)
Query Neighborhood Hits	378	Target Neighborhood Hits	556	Shared Neighborhood Hits	122
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

EPN1_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.062533 (rank : 412)
Query Neighborhood Hits	378	Target Neighborhood Hits	206	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

EPN1_MOUSE
θ value	θ > 10 (rank : 476)	NC score	0.056840 (rank : 472)
Query Neighborhood Hits	378	Target Neighborhood Hits	240	Shared Neighborhood Hits	59
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

FHOD1_MOUSE
θ value	θ > 10 (rank : 477)	NC score	0.053187 (rank : 517)
Query Neighborhood Hits	378	Target Neighborhood Hits	217	Shared Neighborhood Hits	45
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

FMN1A_MOUSE
θ value	θ > 10 (rank : 478)	NC score	0.081513 (rank : 286)
Query Neighborhood Hits	378	Target Neighborhood Hits	423	Shared Neighborhood Hits	102
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

FMN1B_MOUSE
θ value	θ > 10 (rank : 479)	NC score	0.083479 (rank : 278)
Query Neighborhood Hits	378	Target Neighborhood Hits	447	Shared Neighborhood Hits	101
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

FMN2_HUMAN
θ value	θ > 10 (rank : 480)	NC score	0.103644 (rank : 170)
Query Neighborhood Hits	378	Target Neighborhood Hits	484	Shared Neighborhood Hits	99
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

FMN2_MOUSE
θ value	θ > 10 (rank : 481)	NC score	0.077546 (rank : 310)
Query Neighborhood Hits	378	Target Neighborhood Hits	349	Shared Neighborhood Hits	70
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

FMNL_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.107133 (rank : 153)
Query Neighborhood Hits	378	Target Neighborhood Hits	529	Shared Neighborhood Hits	121
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

FMNL_MOUSE
θ value	θ > 10 (rank : 483)	NC score	0.059119 (rank : 444)
Query Neighborhood Hits	378	Target Neighborhood Hits	428	Shared Neighborhood Hits	76
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

GGN_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.144214 (rank : 63)
Query Neighborhood Hits	378	Target Neighborhood Hits	269	Shared Neighborhood Hits	85
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GGN_MOUSE
θ value	θ > 10 (rank : 485)	NC score	0.157597 (rank : 47)
Query Neighborhood Hits	378	Target Neighborhood Hits	311	Shared Neighborhood Hits	106
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GNDS_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.073007 (rank : 334)
Query Neighborhood Hits	378	Target Neighborhood Hits	201	Shared Neighborhood Hits	86
SwissProt Accessions	Q12967, Q9HAX7, Q9HAY1, Q9HCT1	Gene names	RALGDS, RGF
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

GRIN1_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.056365 (rank : 481)
Query Neighborhood Hits	378	Target Neighborhood Hits	681	Shared Neighborhood Hits	87
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

GRIN1_MOUSE
θ value	θ > 10 (rank : 488)	NC score	0.076704 (rank : 318)
Query Neighborhood Hits	378	Target Neighborhood Hits	337	Shared Neighborhood Hits	68
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

GRP3_HUMAN
θ value	θ > 10 (rank : 489)	NC score	0.136028 (rank : 77)
Query Neighborhood Hits	378	Target Neighborhood Hits	131	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

GSCR1_HUMAN
θ value	θ > 10 (rank : 490)	NC score	0.182245 (rank : 31)
Query Neighborhood Hits	378	Target Neighborhood Hits	674	Shared Neighborhood Hits	155
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

HRX_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.073045 (rank : 333)
Query Neighborhood Hits	378	Target Neighborhood Hits	825	Shared Neighborhood Hits	107
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

IASPP_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.114597 (rank : 118)
Query Neighborhood Hits	378	Target Neighborhood Hits	688	Shared Neighborhood Hits	94
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IF35_HUMAN
θ value	θ > 10 (rank : 493)	NC score	0.075839 (rank : 323)
Query Neighborhood Hits	378	Target Neighborhood Hits	130	Shared Neighborhood Hits	54
SwissProt Accessions	O00303, Q8N978	Gene names	EIF3S5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

IF35_MOUSE
θ value	θ > 10 (rank : 494)	NC score	0.094894 (rank : 208)
Query Neighborhood Hits	378	Target Neighborhood Hits	210	Shared Neighborhood Hits	79
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

IF39_HUMAN
θ value	θ > 10 (rank : 495)	NC score	0.052235 (rank : 532)
Query Neighborhood Hits	378	Target Neighborhood Hits	187	Shared Neighborhood Hits	38
SwissProt Accessions	P55884, Q9UMF9	Gene names	EIF3S9
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) (Prt1 homolog) (hPrt1).

IF4G1_HUMAN
θ value	θ > 10 (rank : 496)	NC score	0.091563 (rank : 227)
Query Neighborhood Hits	378	Target Neighborhood Hits	347	Shared Neighborhood Hits	95
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

IRS2_HUMAN
θ value	θ > 10 (rank : 497)	NC score	0.059075 (rank : 445)
Query Neighborhood Hits	378	Target Neighborhood Hits	262	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

JPH2_MOUSE
θ value	θ > 10 (rank : 498)	NC score	0.069471 (rank : 359)
Query Neighborhood Hits	378	Target Neighborhood Hits	279	Shared Neighborhood Hits	73
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

K0310_HUMAN
θ value	θ > 10 (rank : 499)	NC score	0.075876 (rank : 322)
Query Neighborhood Hits	378	Target Neighborhood Hits	420	Shared Neighborhood Hits	78
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

K0460_HUMAN
θ value	θ > 10 (rank : 500)	NC score	0.052002 (rank : 537)
Query Neighborhood Hits	378	Target Neighborhood Hits	357	Shared Neighborhood Hits	61
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

K0460_MOUSE
θ value	θ > 10 (rank : 501)	NC score	0.052246 (rank : 531)
Query Neighborhood Hits	378	Target Neighborhood Hits	374	Shared Neighborhood Hits	59
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

K1683_HUMAN
θ value	θ > 10 (rank : 502)	NC score	0.054103 (rank : 505)
Query Neighborhood Hits	378	Target Neighborhood Hits	240	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

KI67_HUMAN
θ value	θ > 10 (rank : 503)	NC score	0.055452 (rank : 488)
Query Neighborhood Hits	378	Target Neighborhood Hits	581	Shared Neighborhood Hits	53
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

KIP1_HUMAN
θ value	θ > 10 (rank : 504)	NC score	0.071241 (rank : 345)
Query Neighborhood Hits	378	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	Q99828, O00693, O00735, Q6IB49, Q96J54, Q99971	Gene names	CIB1, CIB, KIP, PRKDCIP
Domain Architecture
Description	Calcium and integrin-binding protein 1 (Calmyrin) (DNA-PKcs- interacting protein) (Kinase-interacting protein) (KIP) (CIB) (SNK- interacting protein 2-28) (SIP2-28).

KIP1_MOUSE
θ value	θ > 10 (rank : 505)	NC score	0.078310 (rank : 303)
Query Neighborhood Hits	378	Target Neighborhood Hits	109	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z0F4, Q3TN80	Gene names	Cib1, Cib, Kip, Prkdcip
Domain Architecture
Description	Calcium and integrin-binding protein 1 (Calmyrin) (DNA-PKcs- interacting protein) (Kinase-interacting protein) (KIP) (CIB).

KPCA_HUMAN
θ value	θ > 10 (rank : 506)	NC score	0.071952 (rank : 342)
Query Neighborhood Hits	378	Target Neighborhood Hits	1070	Shared Neighborhood Hits	58
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCA_MOUSE
θ value	θ > 10 (rank : 507)	NC score	0.071494 (rank : 344)
Query Neighborhood Hits	378	Target Neighborhood Hits	1067	Shared Neighborhood Hits	58
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCB_HUMAN
θ value	θ > 10 (rank : 508)	NC score	0.074219 (rank : 326)
Query Neighborhood Hits	378	Target Neighborhood Hits	1121	Shared Neighborhood Hits	58
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCB_MOUSE
θ value	θ > 10 (rank : 509)	NC score	0.074101 (rank : 327)
Query Neighborhood Hits	378	Target Neighborhood Hits	1117	Shared Neighborhood Hits	58
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

LCE2A_HUMAN
θ value	θ > 10 (rank : 510)	NC score	0.078182 (rank : 306)
Query Neighborhood Hits	378	Target Neighborhood Hits	50	Shared Neighborhood Hits	7
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

LCE2B_HUMAN
θ value	θ > 10 (rank : 511)	NC score	0.090076 (rank : 237)
Query Neighborhood Hits	378	Target Neighborhood Hits	50	Shared Neighborhood Hits	9
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

LCE2C_HUMAN
θ value	θ > 10 (rank : 512)	NC score	0.087425 (rank : 253)
Query Neighborhood Hits	378	Target Neighborhood Hits	53	Shared Neighborhood Hits	10
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LCE2D_HUMAN
θ value	θ > 10 (rank : 513)	NC score	0.083501 (rank : 277)
Query Neighborhood Hits	378	Target Neighborhood Hits	50	Shared Neighborhood Hits	8
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

LCE5A_HUMAN
θ value	θ > 10 (rank : 514)	NC score	0.080986 (rank : 289)
Query Neighborhood Hits	378	Target Neighborhood Hits	43	Shared Neighborhood Hits	9
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

LCP2_HUMAN
θ value	θ > 10 (rank : 515)	NC score	0.055787 (rank : 484)
Query Neighborhood Hits	378	Target Neighborhood Hits	531	Shared Neighborhood Hits	73
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LDB3_HUMAN
θ value	θ > 10 (rank : 516)	NC score	0.078269 (rank : 305)
Query Neighborhood Hits	378	Target Neighborhood Hits	497	Shared Neighborhood Hits	104
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

LDB3_MOUSE
θ value	θ > 10 (rank : 517)	NC score	0.071116 (rank : 346)
Query Neighborhood Hits	378	Target Neighborhood Hits	510	Shared Neighborhood Hits	108
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

MADCA_HUMAN
θ value	θ > 10 (rank : 518)	NC score	0.159134 (rank : 45)
Query Neighborhood Hits	378	Target Neighborhood Hits	221	Shared Neighborhood Hits	84
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

MAGC1_HUMAN
θ value	θ > 10 (rank : 519)	NC score	0.050583 (rank : 560)
Query Neighborhood Hits	378	Target Neighborhood Hits	431	Shared Neighborhood Hits	78
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

MAP4_MOUSE
θ value	θ > 10 (rank : 520)	NC score	0.100357 (rank : 183)
Query Neighborhood Hits	378	Target Neighborhood Hits	409	Shared Neighborhood Hits	80
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MARCS_HUMAN
θ value	θ > 10 (rank : 521)	NC score	0.111381 (rank : 130)
Query Neighborhood Hits	378	Target Neighborhood Hits	204	Shared Neighborhood Hits	58
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MARCS_MOUSE
θ value	θ > 10 (rank : 522)	NC score	0.121364 (rank : 99)
Query Neighborhood Hits	378	Target Neighborhood Hits	227	Shared Neighborhood Hits	65
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MAST4_HUMAN
θ value	θ > 10 (rank : 523)	NC score	0.053279 (rank : 516)
Query Neighborhood Hits	378	Target Neighborhood Hits	1804	Shared Neighborhood Hits	147
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MAVS_HUMAN
θ value	θ > 10 (rank : 524)	NC score	0.063038 (rank : 404)
Query Neighborhood Hits	378	Target Neighborhood Hits	271	Shared Neighborhood Hits	52
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

MBB1A_HUMAN
θ value	θ > 10 (rank : 525)	NC score	0.050538 (rank : 561)
Query Neighborhood Hits	378	Target Neighborhood Hits	665	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MBD6_HUMAN
θ value	θ > 10 (rank : 526)	NC score	0.151181 (rank : 52)
Query Neighborhood Hits	378	Target Neighborhood Hits	349	Shared Neighborhood Hits	92
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MCSP_MOUSE
θ value	θ > 10 (rank : 527)	NC score	0.070262 (rank : 353)
Query Neighborhood Hits	378	Target Neighborhood Hits	108	Shared Neighborhood Hits	13
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MEGF9_HUMAN
θ value	θ > 10 (rank : 528)	NC score	0.053443 (rank : 514)
Query Neighborhood Hits	378	Target Neighborhood Hits	557	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MILK1_HUMAN
θ value	θ > 10 (rank : 529)	NC score	0.087326 (rank : 255)
Query Neighborhood Hits	378	Target Neighborhood Hits	427	Shared Neighborhood Hits	94
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MILK2_HUMAN
θ value	θ > 10 (rank : 530)	NC score	0.050623 (rank : 559)
Query Neighborhood Hits	378	Target Neighborhood Hits	457	Shared Neighborhood Hits	73
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

MISS_MOUSE
θ value	θ > 10 (rank : 531)	NC score	0.051967 (rank : 540)
Query Neighborhood Hits	378	Target Neighborhood Hits	444	Shared Neighborhood Hits	57
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

MLL2_HUMAN
θ value	θ > 10 (rank : 532)	NC score	0.138992 (rank : 73)
Query Neighborhood Hits	378	Target Neighborhood Hits	1788	Shared Neighborhood Hits	200
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL4_HUMAN
θ value	θ > 10 (rank : 533)	NC score	0.133339 (rank : 80)
Query Neighborhood Hits	378	Target Neighborhood Hits	722	Shared Neighborhood Hits	145
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MN1_HUMAN
θ value	θ > 10 (rank : 534)	NC score	0.052170 (rank : 534)
Query Neighborhood Hits	378	Target Neighborhood Hits	196	Shared Neighborhood Hits	43
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

MOT8_MOUSE
θ value	θ > 10 (rank : 535)	NC score	0.059500 (rank : 441)
Query Neighborhood Hits	378	Target Neighborhood Hits	96	Shared Neighborhood Hits	56
SwissProt Accessions	O70324, Q8K3S9	Gene names	Slc16a2, Mct8, Xpct
Domain Architecture	No domain graphic available
Description	Monocarboxylate transporter 8 (MCT 8) (Solute carrier family 16 member 2) (X-linked PEST-containing transporter).

MRCKA_HUMAN
θ value	θ > 10 (rank : 536)	NC score	0.052148 (rank : 535)
Query Neighborhood Hits	378	Target Neighborhood Hits	1999	Shared Neighborhood Hits	93
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

MRCKG_HUMAN
θ value	θ > 10 (rank : 537)	NC score	0.052796 (rank : 525)
Query Neighborhood Hits	378	Target Neighborhood Hits	1519	Shared Neighborhood Hits	76
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

MRCKG_MOUSE
θ value	θ > 10 (rank : 538)	NC score	0.055085 (rank : 497)
Query Neighborhood Hits	378	Target Neighborhood Hits	1466	Shared Neighborhood Hits	75
SwissProt Accessions	Q80UW5	Gene names	Cdc42bpg
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

MUC13_MOUSE
θ value	θ > 10 (rank : 539)	NC score	0.069997 (rank : 355)
Query Neighborhood Hits	378	Target Neighborhood Hits	447	Shared Neighborhood Hits	61
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

MUC1_MOUSE
θ value	θ > 10 (rank : 540)	NC score	0.120003 (rank : 104)
Query Neighborhood Hits	378	Target Neighborhood Hits	388	Shared Neighborhood Hits	52
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

MUC2_HUMAN
θ value	θ > 10 (rank : 541)	NC score	0.156428 (rank : 48)
Query Neighborhood Hits	378	Target Neighborhood Hits	906	Shared Neighborhood Hits	158
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MUC5B_HUMAN
θ value	θ > 10 (rank : 542)	NC score	0.082369 (rank : 282)
Query Neighborhood Hits	378	Target Neighborhood Hits	1020	Shared Neighborhood Hits	116
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MUC7_HUMAN
θ value	θ > 10 (rank : 543)	NC score	0.239390 (rank : 16)
Query Neighborhood Hits	378	Target Neighborhood Hits	538	Shared Neighborhood Hits	159
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

MUCDL_HUMAN
θ value	θ > 10 (rank : 544)	NC score	0.083387 (rank : 279)
Query Neighborhood Hits	378	Target Neighborhood Hits	777	Shared Neighborhood Hits	105
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MUCDL_MOUSE
θ value	θ > 10 (rank : 545)	NC score	0.057879 (rank : 461)
Query Neighborhood Hits	378	Target Neighborhood Hits	461	Shared Neighborhood Hits	73
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MYST3_HUMAN
θ value	θ > 10 (rank : 546)	NC score	0.056532 (rank : 478)
Query Neighborhood Hits	378	Target Neighborhood Hits	772	Shared Neighborhood Hits	103
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

NCOR2_HUMAN
θ value	θ > 10 (rank : 547)	NC score	0.086245 (rank : 261)
Query Neighborhood Hits	378	Target Neighborhood Hits	870	Shared Neighborhood Hits	119
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NCOR2_MOUSE
θ value	θ > 10 (rank : 548)	NC score	0.058076 (rank : 457)
Query Neighborhood Hits	378	Target Neighborhood Hits	790	Shared Neighborhood Hits	92
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

NELFA_HUMAN
θ value	θ > 10 (rank : 549)	NC score	0.088969 (rank : 243)
Query Neighborhood Hits	378	Target Neighborhood Hits	161	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H3P2, O95392	Gene names	WHSC2, NELFA
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein).

NELFA_MOUSE
θ value	θ > 10 (rank : 550)	NC score	0.092011 (rank : 224)
Query Neighborhood Hits	378	Target Neighborhood Hits	195	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

NEUM_HUMAN
θ value	θ > 10 (rank : 551)	NC score	0.070694 (rank : 349)
Query Neighborhood Hits	378	Target Neighborhood Hits	132	Shared Neighborhood Hits	36
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

NEUM_MOUSE
θ value	θ > 10 (rank : 552)	NC score	0.063553 (rank : 402)
Query Neighborhood Hits	378	Target Neighborhood Hits	149	Shared Neighborhood Hits	33
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

NFH_HUMAN
θ value	θ > 10 (rank : 553)	NC score	0.065477 (rank : 391)
Query Neighborhood Hits	378	Target Neighborhood Hits	1242	Shared Neighborhood Hits	117
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NFRKB_HUMAN
θ value	θ > 10 (rank : 554)	NC score	0.062433 (rank : 415)
Query Neighborhood Hits	378	Target Neighborhood Hits	211	Shared Neighborhood Hits	38
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

NFRKB_MOUSE
θ value	θ > 10 (rank : 555)	NC score	0.056010 (rank : 483)
Query Neighborhood Hits	378	Target Neighborhood Hits	393	Shared Neighborhood Hits	63
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

NOL3_MOUSE
θ value	θ > 10 (rank : 556)	NC score	0.072880 (rank : 335)
Query Neighborhood Hits	378	Target Neighborhood Hits	97	Shared Neighborhood Hits	45
SwissProt Accessions	Q9D1X0	Gene names	Nol3
Domain Architecture
Description	Nucleolar protein 3.

NOLC1_HUMAN
θ value	θ > 10 (rank : 557)	NC score	0.106284 (rank : 155)
Query Neighborhood Hits	378	Target Neighborhood Hits	452	Shared Neighborhood Hits	75
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

NU214_HUMAN
θ value	θ > 10 (rank : 558)	NC score	0.092377 (rank : 221)
Query Neighborhood Hits	378	Target Neighborhood Hits	657	Shared Neighborhood Hits	88
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

OGFR_MOUSE
θ value	θ > 10 (rank : 559)	NC score	0.078836 (rank : 299)
Query Neighborhood Hits	378	Target Neighborhood Hits	584	Shared Neighborhood Hits	67
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

PARM1_HUMAN
θ value	θ > 10 (rank : 560)	NC score	0.051349 (rank : 548)
Query Neighborhood Hits	378	Target Neighborhood Hits	86	Shared Neighborhood Hits	24
SwissProt Accessions	Q6UWI2, Q96DV8, Q9Y4S1	Gene names	ames=UNQ1879/PRO4322
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

PARM1_MOUSE
θ value	θ > 10 (rank : 561)	NC score	0.058697 (rank : 451)
Query Neighborhood Hits	378	Target Neighborhood Hits	140	Shared Neighborhood Hits	32
SwissProt Accessions	Q923D3, Q3TTV0, Q3UFU4	Gene names
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

PCQAP_HUMAN
θ value	θ > 10 (rank : 562)	NC score	0.106241 (rank : 156)
Query Neighborhood Hits	378	Target Neighborhood Hits	549	Shared Neighborhood Hits	100
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PCQAP_MOUSE
θ value	θ > 10 (rank : 563)	NC score	0.098018 (rank : 196)
Query Neighborhood Hits	378	Target Neighborhood Hits	506	Shared Neighborhood Hits	91
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

PDC6I_HUMAN
θ value	θ > 10 (rank : 564)	NC score	0.079652 (rank : 294)
Query Neighborhood Hits	378	Target Neighborhood Hits	278	Shared Neighborhood Hits	88
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

PDC6I_MOUSE
θ value	θ > 10 (rank : 565)	NC score	0.067346 (rank : 378)
Query Neighborhood Hits	378	Target Neighborhood Hits	275	Shared Neighborhood Hits	75
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

PDCD7_HUMAN
θ value	θ > 10 (rank : 566)	NC score	0.058896 (rank : 449)
Query Neighborhood Hits	378	Target Neighborhood Hits	255	Shared Neighborhood Hits	42
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

PDZD8_HUMAN
θ value	θ > 10 (rank : 567)	NC score	0.104707 (rank : 165)
Query Neighborhood Hits	378	Target Neighborhood Hits	185	Shared Neighborhood Hits	42
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PELP1_HUMAN
θ value	θ > 10 (rank : 568)	NC score	0.119006 (rank : 105)
Query Neighborhood Hits	378	Target Neighborhood Hits	596	Shared Neighborhood Hits	119
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PELP1_MOUSE
θ value	θ > 10 (rank : 569)	NC score	0.112337 (rank : 124)
Query Neighborhood Hits	378	Target Neighborhood Hits	709	Shared Neighborhood Hits	119
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PER1_HUMAN
θ value	θ > 10 (rank : 570)	NC score	0.056484 (rank : 480)
Query Neighborhood Hits	378	Target Neighborhood Hits	215	Shared Neighborhood Hits	69
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PER1_MOUSE
θ value	θ > 10 (rank : 571)	NC score	0.052837 (rank : 523)
Query Neighborhood Hits	378	Target Neighborhood Hits	235	Shared Neighborhood Hits	67
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

PHC1_HUMAN
θ value	θ > 10 (rank : 572)	NC score	0.054758 (rank : 499)
Query Neighborhood Hits	378	Target Neighborhood Hits	227	Shared Neighborhood Hits	48
SwissProt Accessions	P78364, Q8WVM3, Q9BU63	Gene names	PHC1, EDR1, PH1
Domain Architecture
Description	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1).

PHC2_MOUSE
θ value	θ > 10 (rank : 573)	NC score	0.055396 (rank : 489)
Query Neighborhood Hits	378	Target Neighborhood Hits	156	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QWH1, O88463, Q8K5D9	Gene names	Phc2, Edr2, Ph2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (mPH2) (Early development regulatory protein 2) (p36).

PHC3_MOUSE
θ value	θ > 10 (rank : 574)	NC score	0.054129 (rank : 504)
Query Neighborhood Hits	378	Target Neighborhood Hits	194	Shared Neighborhood Hits	49
SwissProt Accessions	Q8CHP6, Q3TLV5	Gene names	Phc3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3.

PHLA1_HUMAN
θ value	θ > 10 (rank : 575)	NC score	0.066453 (rank : 384)
Query Neighborhood Hits	378	Target Neighborhood Hits	121	Shared Neighborhood Hits	46
SwissProt Accessions	Q8WV24, Q15184, Q2TAN2, Q9NZ17	Gene names	PHLDA1, PHRIP, TDAG51
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family A member 1 (T-cell death- associated gene 51 protein) (Apoptosis-associated nuclear protein) (Proline- and histidine-rich protein) (Proline- and glutamine-rich protein) (PQ-rich protein).

PI5PA_MOUSE
θ value	θ > 10 (rank : 576)	NC score	0.093095 (rank : 215)
Query Neighborhood Hits	378	Target Neighborhood Hits	331	Shared Neighborhood Hits	88
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PKHA2_MOUSE
θ value	θ > 10 (rank : 577)	NC score	0.080751 (rank : 290)
Query Neighborhood Hits	378	Target Neighborhood Hits	116	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

PKHA4_HUMAN
θ value	θ > 10 (rank : 578)	NC score	0.082340 (rank : 283)
Query Neighborhood Hits	378	Target Neighborhood Hits	283	Shared Neighborhood Hits	77
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA4_MOUSE
θ value	θ > 10 (rank : 579)	NC score	0.068404 (rank : 367)
Query Neighborhood Hits	378	Target Neighborhood Hits	202	Shared Neighborhood Hits	52
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA6_HUMAN
θ value	θ > 10 (rank : 580)	NC score	0.053827 (rank : 507)
Query Neighborhood Hits	378	Target Neighborhood Hits	556	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_MOUSE
θ value	θ > 10 (rank : 581)	NC score	0.060094 (rank : 437)
Query Neighborhood Hits	378	Target Neighborhood Hits	591	Shared Neighborhood Hits	74
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PO121_HUMAN
θ value	θ > 10 (rank : 582)	NC score	0.112029 (rank : 126)
Query Neighborhood Hits	378	Target Neighborhood Hits	344	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PO121_MOUSE
θ value	θ > 10 (rank : 583)	NC score	0.101697 (rank : 176)
Query Neighborhood Hits	378	Target Neighborhood Hits	345	Shared Neighborhood Hits	69
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

PO6F2_MOUSE
θ value	θ > 10 (rank : 584)	NC score	0.051268 (rank : 550)
Query Neighborhood Hits	378	Target Neighborhood Hits	639	Shared Neighborhood Hits	93
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

PPRB_MOUSE
θ value	θ > 10 (rank : 585)	NC score	0.057914 (rank : 460)
Query Neighborhood Hits	378	Target Neighborhood Hits	354	Shared Neighborhood Hits	57
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

PRAX_HUMAN
θ value	θ > 10 (rank : 586)	NC score	0.077132 (rank : 312)
Query Neighborhood Hits	378	Target Neighborhood Hits	215	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

PRAX_MOUSE
θ value	θ > 10 (rank : 587)	NC score	0.072069 (rank : 341)
Query Neighborhood Hits	378	Target Neighborhood Hits	199	Shared Neighborhood Hits	43
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

PRB3_HUMAN
θ value	θ > 10 (rank : 588)	NC score	0.187808 (rank : 27)
Query Neighborhood Hits	378	Target Neighborhood Hits	318	Shared Neighborhood Hits	93
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 589)	NC score	0.183314 (rank : 29)
Query Neighborhood Hits	378	Target Neighborhood Hits	330	Shared Neighborhood Hits	96
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRCC_HUMAN
θ value	θ > 10 (rank : 590)	NC score	0.052811 (rank : 524)
Query Neighborhood Hits	378	Target Neighborhood Hits	109	Shared Neighborhood Hits	30
SwissProt Accessions	Q92733, O00665, O00724	Gene names	PRCC, TPRC
Domain Architecture	No domain graphic available
Description	Proline-rich protein PRCC (Papillary renal cell carcinoma translocation-associated gene protein).

PRG4_HUMAN
θ value	θ > 10 (rank : 591)	NC score	0.235673 (rank : 17)
Query Neighborhood Hits	378	Target Neighborhood Hits	764	Shared Neighborhood Hits	162
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRG4_MOUSE
θ value	θ > 10 (rank : 592)	NC score	0.213031 (rank : 20)
Query Neighborhood Hits	378	Target Neighborhood Hits	624	Shared Neighborhood Hits	151
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRP1_HUMAN
θ value	θ > 10 (rank : 593)	NC score	0.193006 (rank : 25)
Query Neighborhood Hits	378	Target Neighborhood Hits	385	Shared Neighborhood Hits	103
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 594)	NC score	0.240063 (rank : 15)
Query Neighborhood Hits	378	Target Neighborhood Hits	347	Shared Neighborhood Hits	110
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRP5_HUMAN
θ value	θ > 10 (rank : 595)	NC score	0.090623 (rank : 233)
Query Neighborhood Hits	378	Target Neighborhood Hits	108	Shared Neighborhood Hits	37
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

PRPC_HUMAN
θ value	θ > 10 (rank : 596)	NC score	0.090219 (rank : 236)
Query Neighborhood Hits	378	Target Neighborhood Hits	165	Shared Neighborhood Hits	41
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

PRPE_HUMAN
θ value	θ > 10 (rank : 597)	NC score	0.060351 (rank : 434)
Query Neighborhood Hits	378	Target Neighborhood Hits	44	Shared Neighborhood Hits	15
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

PRR12_HUMAN
θ value	θ > 10 (rank : 598)	NC score	0.226032 (rank : 18)
Query Neighborhood Hits	378	Target Neighborhood Hits	460	Shared Neighborhood Hits	156
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PRR13_HUMAN
θ value	θ > 10 (rank : 599)	NC score	0.131193 (rank : 85)
Query Neighborhood Hits	378	Target Neighborhood Hits	105	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PRR13_MOUSE
θ value	θ > 10 (rank : 600)	NC score	0.104951 (rank : 162)
Query Neighborhood Hits	378	Target Neighborhood Hits	54	Shared Neighborhood Hits	21
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PRR8_HUMAN
θ value	θ > 10 (rank : 601)	NC score	0.069971 (rank : 356)
Query Neighborhood Hits	378	Target Neighborhood Hits	217	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

PRRT1_HUMAN
θ value	θ > 10 (rank : 602)	NC score	0.062709 (rank : 409)
Query Neighborhood Hits	378	Target Neighborhood Hits	94	Shared Neighborhood Hits	34
SwissProt Accessions	Q99946, Q96DW3, Q96NQ8	Gene names	PRRT1, C6orf31, NG5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

PRRT1_MOUSE
θ value	θ > 10 (rank : 603)	NC score	0.068993 (rank : 361)
Query Neighborhood Hits	378	Target Neighborhood Hits	102	Shared Neighborhood Hits	36
SwissProt Accessions	O35449	Gene names	Prrt1, Ng5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

PS1C2_HUMAN
θ value	θ > 10 (rank : 604)	NC score	0.108858 (rank : 142)
Query Neighborhood Hits	378	Target Neighborhood Hits	66	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UIG4	Gene names	PSORS1C2, C6orf17, SPR1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein precursor (SPR1 protein).

PS1C2_MOUSE
θ value	θ > 10 (rank : 605)	NC score	0.083639 (rank : 275)
Query Neighborhood Hits	378	Target Neighborhood Hits	59	Shared Neighborhood Hits	23
SwissProt Accessions	Q80ZC9	Gene names	Psors1c2, Spr1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein homolog precursor (SPR1 protein).

PTN23_HUMAN
θ value	θ > 10 (rank : 606)	NC score	0.072617 (rank : 338)
Query Neighborhood Hits	378	Target Neighborhood Hits	646	Shared Neighborhood Hits	122
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PXK_MOUSE
θ value	θ > 10 (rank : 607)	NC score	0.051354 (rank : 547)
Query Neighborhood Hits	378	Target Neighborhood Hits	320	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BX57, Q3TD60, Q3TEL7, Q3TZZ1, Q3U197, Q3U773, Q3UCS5, Q4FBH7, Q91WB6	Gene names	Pxk
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

PYGO2_HUMAN
θ value	θ > 10 (rank : 608)	NC score	0.050444 (rank : 563)
Query Neighborhood Hits	378	Target Neighborhood Hits	189	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

RANB9_HUMAN
θ value	θ > 10 (rank : 609)	NC score	0.055153 (rank : 495)
Query Neighborhood Hits	378	Target Neighborhood Hits	179	Shared Neighborhood Hits	56
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

RAPH1_HUMAN
θ value	θ > 10 (rank : 610)	NC score	0.169963 (rank : 39)
Query Neighborhood Hits	378	Target Neighborhood Hits	593	Shared Neighborhood Hits	158
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RASA2_HUMAN
θ value	θ > 10 (rank : 611)	NC score	0.054677 (rank : 500)
Query Neighborhood Hits	378	Target Neighborhood Hits	157	Shared Neighborhood Hits	29
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RASA2_MOUSE
θ value	θ > 10 (rank : 612)	NC score	0.055315 (rank : 492)
Query Neighborhood Hits	378	Target Neighborhood Hits	159	Shared Neighborhood Hits	32
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RASF1_HUMAN
θ value	θ > 10 (rank : 613)	NC score	0.089573 (rank : 241)
Query Neighborhood Hits	378	Target Neighborhood Hits	62	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NS23, O14571, O60539, O60710, Q9HB04, Q9HB18, Q9NS22, Q9UND4, Q9UND5	Gene names	RASSF1, RDA32
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1.

RASF1_MOUSE
θ value	θ > 10 (rank : 614)	NC score	0.132731 (rank : 81)
Query Neighborhood Hits	378	Target Neighborhood Hits	74	Shared Neighborhood Hits	31
SwissProt Accessions	Q99MK9, Q9WUF5	Gene names	Rassf1
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1 (Protein 123F2).

RBM12_HUMAN
θ value	θ > 10 (rank : 615)	NC score	0.056623 (rank : 476)
Query Neighborhood Hits	378	Target Neighborhood Hits	298	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

RBM12_MOUSE
θ value	θ > 10 (rank : 616)	NC score	0.070649 (rank : 350)
Query Neighborhood Hits	378	Target Neighborhood Hits	313	Shared Neighborhood Hits	66
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

RD23B_MOUSE
θ value	θ > 10 (rank : 617)	NC score	0.068140 (rank : 372)
Query Neighborhood Hits	378	Target Neighborhood Hits	189	Shared Neighborhood Hits	54
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

RERE_HUMAN
θ value	θ > 10 (rank : 618)	NC score	0.134462 (rank : 79)
Query Neighborhood Hits	378	Target Neighborhood Hits	779	Shared Neighborhood Hits	147
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RERE_MOUSE
θ value	θ > 10 (rank : 619)	NC score	0.126736 (rank : 91)
Query Neighborhood Hits	378	Target Neighborhood Hits	785	Shared Neighborhood Hits	150
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RFX1_HUMAN
θ value	θ > 10 (rank : 620)	NC score	0.062914 (rank : 406)
Query Neighborhood Hits	378	Target Neighborhood Hits	256	Shared Neighborhood Hits	73
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

RIN3_HUMAN
θ value	θ > 10 (rank : 621)	NC score	0.079015 (rank : 296)
Query Neighborhood Hits	378	Target Neighborhood Hits	227	Shared Neighborhood Hits	74
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RIN3_MOUSE
θ value	θ > 10 (rank : 622)	NC score	0.083917 (rank : 272)
Query Neighborhood Hits	378	Target Neighborhood Hits	239	Shared Neighborhood Hits	68
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RPB1_HUMAN
θ value	θ > 10 (rank : 623)	NC score	0.092930 (rank : 217)
Query Neighborhood Hits	378	Target Neighborhood Hits	362	Shared Neighborhood Hits	80
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	θ > 10 (rank : 624)	NC score	0.092580 (rank : 219)
Query Neighborhood Hits	378	Target Neighborhood Hits	363	Shared Neighborhood Hits	78
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RTN4_HUMAN
θ value	θ > 10 (rank : 625)	NC score	0.077627 (rank : 309)
Query Neighborhood Hits	378	Target Neighborhood Hits	357	Shared Neighborhood Hits	87
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

RTN4_MOUSE
θ value	θ > 10 (rank : 626)	NC score	0.064980 (rank : 396)
Query Neighborhood Hits	378	Target Neighborhood Hits	341	Shared Neighborhood Hits	76
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

RU1C_HUMAN
θ value	θ > 10 (rank : 627)	NC score	0.056567 (rank : 477)
Query Neighborhood Hits	378	Target Neighborhood Hits	81	Shared Neighborhood Hits	24
SwissProt Accessions	P09234	Gene names	SNRPC
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

RU1C_MOUSE
θ value	θ > 10 (rank : 628)	NC score	0.056711 (rank : 473)
Query Neighborhood Hits	378	Target Neighborhood Hits	83	Shared Neighborhood Hits	25
SwissProt Accessions	Q62241	Gene names	Snrp1c, Snrpc
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

SAM14_HUMAN
θ value	θ > 10 (rank : 629)	NC score	0.062311 (rank : 417)
Query Neighborhood Hits	378	Target Neighborhood Hits	81	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IZD0, Q8N2X0	Gene names	SAMD14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

SAM14_MOUSE
θ value	θ > 10 (rank : 630)	NC score	0.055247 (rank : 493)
Query Neighborhood Hits	378	Target Neighborhood Hits	91	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K070, Q5SWB7, Q8BHE2, Q8C8N5	Gene names	Samd14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

SC24C_HUMAN
θ value	θ > 10 (rank : 631)	NC score	0.053344 (rank : 515)
Query Neighborhood Hits	378	Target Neighborhood Hits	662	Shared Neighborhood Hits	71
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SDC3_MOUSE
θ value	θ > 10 (rank : 632)	NC score	0.083903 (rank : 273)
Query Neighborhood Hits	378	Target Neighborhood Hits	107	Shared Neighborhood Hits	41
SwissProt Accessions	Q64519, Q3UDD9, Q6ZQA4, Q7TQD4	Gene names	Sdc3, Kiaa0468
Domain Architecture
Description	Syndecan-3 precursor (SYND3).

SELPL_HUMAN
θ value	θ > 10 (rank : 633)	NC score	0.103963 (rank : 169)
Query Neighborhood Hits	378	Target Neighborhood Hits	68	Shared Neighborhood Hits	24
SwissProt Accessions	Q14242, Q12775	Gene names	SELPLG
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand) (CD162 antigen).

SELV_HUMAN
θ value	θ > 10 (rank : 634)	NC score	0.158487 (rank : 46)
Query Neighborhood Hits	378	Target Neighborhood Hits	118	Shared Neighborhood Hits	57
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

SET1A_HUMAN
θ value	θ > 10 (rank : 635)	NC score	0.137930 (rank : 75)
Query Neighborhood Hits	378	Target Neighborhood Hits	690	Shared Neighborhood Hits	137
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SF01_HUMAN
θ value	θ > 10 (rank : 636)	NC score	0.093727 (rank : 213)
Query Neighborhood Hits	378	Target Neighborhood Hits	287	Shared Neighborhood Hits	80
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SF01_MOUSE
θ value	θ > 10 (rank : 637)	NC score	0.077077 (rank : 313)
Query Neighborhood Hits	378	Target Neighborhood Hits	240	Shared Neighborhood Hits	61
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SF3A1_HUMAN
θ value	θ > 10 (rank : 638)	NC score	0.076343 (rank : 319)
Query Neighborhood Hits	378	Target Neighborhood Hits	199	Shared Neighborhood Hits	64
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

SF3A1_MOUSE
θ value	θ > 10 (rank : 639)	NC score	0.067636 (rank : 377)
Query Neighborhood Hits	378	Target Neighborhood Hits	198	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

SF3A2_HUMAN
θ value	θ > 10 (rank : 640)	NC score	0.147562 (rank : 59)
Query Neighborhood Hits	378	Target Neighborhood Hits	263	Shared Neighborhood Hits	90
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SF3A2_MOUSE
θ value	θ > 10 (rank : 641)	NC score	0.153551 (rank : 50)
Query Neighborhood Hits	378	Target Neighborhood Hits	247	Shared Neighborhood Hits	86
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SFPQ_HUMAN
θ value	θ > 10 (rank : 642)	NC score	0.115854 (rank : 114)
Query Neighborhood Hits	378	Target Neighborhood Hits	986	Shared Neighborhood Hits	156
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SFPQ_MOUSE
θ value	θ > 10 (rank : 643)	NC score	0.117692 (rank : 110)
Query Neighborhood Hits	378	Target Neighborhood Hits	958	Shared Neighborhood Hits	140
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SFR15_HUMAN
θ value	θ > 10 (rank : 644)	NC score	0.107686 (rank : 150)
Query Neighborhood Hits	378	Target Neighborhood Hits	368	Shared Neighborhood Hits	80
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SGIP1_HUMAN
θ value	θ > 10 (rank : 645)	NC score	0.093182 (rank : 214)
Query Neighborhood Hits	378	Target Neighborhood Hits	198	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SGIP1_MOUSE
θ value	θ > 10 (rank : 646)	NC score	0.092184 (rank : 223)
Query Neighborhood Hits	378	Target Neighborhood Hits	180	Shared Neighborhood Hits	64
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SHAN1_HUMAN
θ value	θ > 10 (rank : 647)	NC score	0.100391 (rank : 182)
Query Neighborhood Hits	378	Target Neighborhood Hits	1041	Shared Neighborhood Hits	140
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SHAN2_HUMAN
θ value	θ > 10 (rank : 648)	NC score	0.096358 (rank : 203)
Query Neighborhood Hits	378	Target Neighborhood Hits	346	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SMOO_HUMAN
θ value	θ > 10 (rank : 649)	NC score	0.080447 (rank : 291)
Query Neighborhood Hits	378	Target Neighborhood Hits	391	Shared Neighborhood Hits	92
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

SMR1_MOUSE
θ value	θ > 10 (rank : 650)	NC score	0.120215 (rank : 102)
Query Neighborhood Hits	378	Target Neighborhood Hits	103	Shared Neighborhood Hits	44
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

SMR3A_HUMAN
θ value	θ > 10 (rank : 651)	NC score	0.105689 (rank : 158)
Query Neighborhood Hits	378	Target Neighborhood Hits	93	Shared Neighborhood Hits	34
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

SMRC2_HUMAN
θ value	θ > 10 (rank : 652)	NC score	0.059014 (rank : 446)
Query Neighborhood Hits	378	Target Neighborhood Hits	499	Shared Neighborhood Hits	74
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SMRC2_MOUSE
θ value	θ > 10 (rank : 653)	NC score	0.059807 (rank : 439)
Query Neighborhood Hits	378	Target Neighborhood Hits	487	Shared Neighborhood Hits	73
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SPEG_HUMAN
θ value	θ > 10 (rank : 654)	NC score	0.057243 (rank : 468)
Query Neighborhood Hits	378	Target Neighborhood Hits	1762	Shared Neighborhood Hits	182
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SPR2A_HUMAN
θ value	θ > 10 (rank : 655)	NC score	0.100610 (rank : 181)
Query Neighborhood Hits	378	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	P35326	Gene names	SPRR2A
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2A (SPR-2A) (2-1).

SPR2B_HUMAN
θ value	θ > 10 (rank : 656)	NC score	0.109032 (rank : 141)
Query Neighborhood Hits	378	Target Neighborhood Hits	24	Shared Neighborhood Hits	8
SwissProt Accessions	P35325, Q5T528	Gene names	SPRR2B
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B (SPR-2B).

SPR2B_MOUSE
θ value	θ > 10 (rank : 657)	NC score	0.090781 (rank : 232)
Query Neighborhood Hits	378	Target Neighborhood Hits	51	Shared Neighborhood Hits	12
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

SPR2D_HUMAN
θ value	θ > 10 (rank : 658)	NC score	0.115377 (rank : 115)
Query Neighborhood Hits	378	Target Neighborhood Hits	30	Shared Neighborhood Hits	10
SwissProt Accessions	P22532, Q5T523, Q96RM3	Gene names	SPRR2D
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D (SPR-2D) (Small proline-rich protein II) (SPR-II).

SPR2D_MOUSE
θ value	θ > 10 (rank : 659)	NC score	0.118760 (rank : 108)
Query Neighborhood Hits	378	Target Neighborhood Hits	61	Shared Neighborhood Hits	20
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

SPR2E_HUMAN
θ value	θ > 10 (rank : 660)	NC score	0.098833 (rank : 192)
Query Neighborhood Hits	378	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

SPR2E_MOUSE
θ value	θ > 10 (rank : 661)	NC score	0.110913 (rank : 134)
Query Neighborhood Hits	378	Target Neighborhood Hits	45	Shared Neighborhood Hits	14
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

SPR2F_HUMAN
θ value	θ > 10 (rank : 662)	NC score	0.087225 (rank : 256)
Query Neighborhood Hits	378	Target Neighborhood Hits	33	Shared Neighborhood Hits	8
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

SPR2F_MOUSE
θ value	θ > 10 (rank : 663)	NC score	0.104923 (rank : 163)
Query Neighborhood Hits	378	Target Neighborhood Hits	43	Shared Neighborhood Hits	15
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

SPR2G_HUMAN
θ value	θ > 10 (rank : 664)	NC score	0.097841 (rank : 197)
Query Neighborhood Hits	378	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYE4	Gene names	SPRR2G
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G (SPR-2G).

SPR2G_MOUSE
θ value	θ > 10 (rank : 665)	NC score	0.111513 (rank : 129)
Query Neighborhood Hits	378	Target Neighborhood Hits	53	Shared Neighborhood Hits	15
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

SPR2H_MOUSE
θ value	θ > 10 (rank : 666)	NC score	0.131924 (rank : 84)
Query Neighborhood Hits	378	Target Neighborhood Hits	82	Shared Neighborhood Hits	28
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

SPR2I_MOUSE
θ value	θ > 10 (rank : 667)	NC score	0.108188 (rank : 147)
Query Neighborhood Hits	378	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

SPR2K_MOUSE
θ value	θ > 10 (rank : 668)	NC score	0.083939 (rank : 271)
Query Neighborhood Hits	378	Target Neighborhood Hits	28	Shared Neighborhood Hits	6
SwissProt Accessions	O70562	Gene names	Sprr2k
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2K.

SPRR4_HUMAN
θ value	θ > 10 (rank : 669)	NC score	0.054473 (rank : 502)
Query Neighborhood Hits	378	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q96PI1, Q2M1Y7, Q5T522	Gene names	SPRR4
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 4.

SPTA3_MOUSE
θ value	θ > 10 (rank : 670)	NC score	0.064797 (rank : 398)
Query Neighborhood Hits	378	Target Neighborhood Hits	74	Shared Neighborhood Hits	34
SwissProt Accessions	Q9D9T6, Q80ZS4, Q9D5L5, Q9DAF5	Gene names	Spata3, Tsarg1
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 3 (Testis spermatocyte apoptosis- related protein 1) (Testis and spermatogenesis cell-related protein 1) (mTSARG1).

SRBP1_HUMAN
θ value	θ > 10 (rank : 671)	NC score	0.054037 (rank : 506)
Query Neighborhood Hits	378	Target Neighborhood Hits	225	Shared Neighborhood Hits	50
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SRBP1_MOUSE
θ value	θ > 10 (rank : 672)	NC score	0.051762 (rank : 543)
Query Neighborhood Hits	378	Target Neighborhood Hits	384	Shared Neighborhood Hits	57
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SRCA_HUMAN
θ value	θ > 10 (rank : 673)	NC score	0.051772 (rank : 542)
Query Neighborhood Hits	378	Target Neighborhood Hits	380	Shared Neighborhood Hits	60
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

SRRM1_HUMAN
θ value	θ > 10 (rank : 674)	NC score	0.176809 (rank : 37)
Query Neighborhood Hits	378	Target Neighborhood Hits	690	Shared Neighborhood Hits	131
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM2_HUMAN
θ value	θ > 10 (rank : 675)	NC score	0.138672 (rank : 74)
Query Neighborhood Hits	378	Target Neighborhood Hits	1296	Shared Neighborhood Hits	165
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

STAC3_HUMAN
θ value	θ > 10 (rank : 676)	NC score	0.107943 (rank : 148)
Query Neighborhood Hits	378	Target Neighborhood Hits	228	Shared Neighborhood Hits	41
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	θ > 10 (rank : 677)	NC score	0.107290 (rank : 151)
Query Neighborhood Hits	378	Target Neighborhood Hits	232	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC_HUMAN
θ value	θ > 10 (rank : 678)	NC score	0.120582 (rank : 100)
Query Neighborhood Hits	378	Target Neighborhood Hits	276	Shared Neighborhood Hits	43
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAC_MOUSE
θ value	θ > 10 (rank : 679)	NC score	0.125202 (rank : 95)
Query Neighborhood Hits	378	Target Neighborhood Hits	268	Shared Neighborhood Hits	44
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAP1_HUMAN
θ value	θ > 10 (rank : 680)	NC score	0.060840 (rank : 428)
Query Neighborhood Hits	378	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULZ2	Gene names	STAP1, BRDG1
Domain Architecture	No domain graphic available
Description	Signal-transducing adaptor protein 1 (STAP-1) (Stem cell adaptor protein 1) (BCR downstream signaling protein 1) (Docking protein BRDG1).

STAP1_MOUSE
θ value	θ > 10 (rank : 681)	NC score	0.051100 (rank : 553)
Query Neighborhood Hits	378	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JM90, Q3TRM1, Q6PES6	Gene names	Stap1
Domain Architecture	No domain graphic available
Description	Signal-transducing adaptor protein 1 (STAP-1) (Stem cell adaptor protein 1).

SYN1_HUMAN
θ value	θ > 10 (rank : 682)	NC score	0.111249 (rank : 131)
Query Neighborhood Hits	378	Target Neighborhood Hits	419	Shared Neighborhood Hits	120
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

SYN1_MOUSE
θ value	θ > 10 (rank : 683)	NC score	0.102547 (rank : 173)
Query Neighborhood Hits	378	Target Neighborhood Hits	363	Shared Neighborhood Hits	105
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

SYN2_HUMAN
θ value	θ > 10 (rank : 684)	NC score	0.058222 (rank : 455)
Query Neighborhood Hits	378	Target Neighborhood Hits	213	Shared Neighborhood Hits	66
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

SYNJ1_HUMAN
θ value	θ > 10 (rank : 685)	NC score	0.100721 (rank : 180)
Query Neighborhood Hits	378	Target Neighborhood Hits	498	Shared Neighborhood Hits	128
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SYNJ1_MOUSE
θ value	θ > 10 (rank : 686)	NC score	0.098069 (rank : 195)
Query Neighborhood Hits	378	Target Neighborhood Hits	516	Shared Neighborhood Hits	121
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SYP2L_HUMAN
θ value	θ > 10 (rank : 687)	NC score	0.083559 (rank : 276)
Query Neighborhood Hits	378	Target Neighborhood Hits	400	Shared Neighborhood Hits	92
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

SYP2L_MOUSE
θ value	θ > 10 (rank : 688)	NC score	0.066630 (rank : 383)
Query Neighborhood Hits	378	Target Neighborhood Hits	289	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

TAF3_HUMAN
θ value	θ > 10 (rank : 689)	NC score	0.061517 (rank : 420)
Query Neighborhood Hits	378	Target Neighborhood Hits	568	Shared Neighborhood Hits	71
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TAF3_MOUSE
θ value	θ > 10 (rank : 690)	NC score	0.055538 (rank : 487)
Query Neighborhood Hits	378	Target Neighborhood Hits	463	Shared Neighborhood Hits	57
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TAF4_HUMAN
θ value	θ > 10 (rank : 691)	NC score	0.174893 (rank : 38)
Query Neighborhood Hits	378	Target Neighborhood Hits	687	Shared Neighborhood Hits	133
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TARA_HUMAN
θ value	θ > 10 (rank : 692)	NC score	0.081206 (rank : 288)
Query Neighborhood Hits	378	Target Neighborhood Hits	1626	Shared Neighborhood Hits	156
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TAU_MOUSE
θ value	θ > 10 (rank : 693)	NC score	0.062741 (rank : 408)
Query Neighborhood Hits	378	Target Neighborhood Hits	502	Shared Neighborhood Hits	70
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TB182_HUMAN
θ value	θ > 10 (rank : 694)	NC score	0.076764 (rank : 317)
Query Neighborhood Hits	378	Target Neighborhood Hits	414	Shared Neighborhood Hits	80
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

TCOF_HUMAN
θ value	θ > 10 (rank : 695)	NC score	0.090062 (rank : 238)
Query Neighborhood Hits	378	Target Neighborhood Hits	543	Shared Neighborhood Hits	78
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TCOF_MOUSE
θ value	θ > 10 (rank : 696)	NC score	0.111184 (rank : 132)
Query Neighborhood Hits	378	Target Neighborhood Hits	471	Shared Neighborhood Hits	83
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TCRG1_HUMAN
θ value	θ > 10 (rank : 697)	NC score	0.062159 (rank : 418)
Query Neighborhood Hits	378	Target Neighborhood Hits	929	Shared Neighborhood Hits	86
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	θ > 10 (rank : 698)	NC score	0.068356 (rank : 369)
Query Neighborhood Hits	378	Target Neighborhood Hits	947	Shared Neighborhood Hits	96
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TFG_HUMAN
θ value	θ > 10 (rank : 699)	NC score	0.059670 (rank : 440)
Query Neighborhood Hits	378	Target Neighborhood Hits	122	Shared Neighborhood Hits	35
SwissProt Accessions	Q92734, Q15656	Gene names	TFG
Domain Architecture
Description	Protein TFG (TRK-fused gene protein).

TGON2_HUMAN
θ value	θ > 10 (rank : 700)	NC score	0.066063 (rank : 389)
Query Neighborhood Hits	378	Target Neighborhood Hits	1037	Shared Neighborhood Hits	84
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TITIN_HUMAN
θ value	θ > 10 (rank : 701)	NC score	0.056906 (rank : 471)
Query Neighborhood Hits	378	Target Neighborhood Hits	2923	Shared Neighborhood Hits	184
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TM108_HUMAN
θ value	θ > 10 (rank : 702)	NC score	0.072772 (rank : 336)
Query Neighborhood Hits	378	Target Neighborhood Hits	166	Shared Neighborhood Hits	48
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TM108_MOUSE
θ value	θ > 10 (rank : 703)	NC score	0.073214 (rank : 331)
Query Neighborhood Hits	378	Target Neighborhood Hits	336	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TMAP1_HUMAN
θ value	θ > 10 (rank : 704)	NC score	0.113123 (rank : 122)
Query Neighborhood Hits	378	Target Neighborhood Hits	140	Shared Neighborhood Hits	49
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

TP53B_MOUSE
θ value	θ > 10 (rank : 705)	NC score	0.058942 (rank : 448)
Query Neighborhood Hits	378	Target Neighborhood Hits	644	Shared Neighborhood Hits	77
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TROAP_HUMAN
θ value	θ > 10 (rank : 706)	NC score	0.089995 (rank : 239)
Query Neighborhood Hits	378	Target Neighborhood Hits	258	Shared Neighborhood Hits	60
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

UN13A_HUMAN
θ value	θ > 10 (rank : 707)	NC score	0.112757 (rank : 123)
Query Neighborhood Hits	378	Target Neighborhood Hits	285	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

VASP_HUMAN
θ value	θ > 10 (rank : 708)	NC score	0.057946 (rank : 459)
Query Neighborhood Hits	378	Target Neighborhood Hits	201	Shared Neighborhood Hits	51
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

VASP_MOUSE
θ value	θ > 10 (rank : 709)	NC score	0.053575 (rank : 511)
Query Neighborhood Hits	378	Target Neighborhood Hits	195	Shared Neighborhood Hits	50
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

VAV2_HUMAN
θ value	θ > 10 (rank : 710)	NC score	0.057724 (rank : 463)
Query Neighborhood Hits	378	Target Neighborhood Hits	453	Shared Neighborhood Hits	55
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
θ value	θ > 10 (rank : 711)	NC score	0.052359 (rank : 527)
Query Neighborhood Hits	378	Target Neighborhood Hits	456	Shared Neighborhood Hits	55
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

VAV_HUMAN
θ value	θ > 10 (rank : 712)	NC score	0.051519 (rank : 544)
Query Neighborhood Hits	378	Target Neighborhood Hits	452	Shared Neighborhood Hits	51
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

VCX1_HUMAN
θ value	θ > 10 (rank : 713)	NC score	0.096256 (rank : 206)
Query Neighborhood Hits	378	Target Neighborhood Hits	129	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

VCX2_HUMAN
θ value	θ > 10 (rank : 714)	NC score	0.060148 (rank : 436)
Query Neighborhood Hits	378	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H322, Q9P0H5	Gene names	VCX2, VCX2R, VCXB
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 2 (VCX-B protein) (Variably charged protein X-B) (Variable charge protein on X with two repeats) (VCX-2r).

VCX3_HUMAN
θ value	θ > 10 (rank : 715)	NC score	0.099100 (rank : 190)
Query Neighborhood Hits	378	Target Neighborhood Hits	105	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

VCXC_HUMAN
θ value	θ > 10 (rank : 716)	NC score	0.096332 (rank : 204)
Query Neighborhood Hits	378	Target Neighborhood Hits	139	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

VCY1_HUMAN
θ value	θ > 10 (rank : 717)	NC score	0.057461 (rank : 466)
Query Neighborhood Hits	378	Target Neighborhood Hits	38	Shared Neighborhood Hits	11
SwissProt Accessions	O14598	Gene names	VCY, BPY1
Domain Architecture	No domain graphic available
Description	Testis-specific basic protein Y 1 (Variably charged protein Y).

VGF_HUMAN
θ value	θ > 10 (rank : 718)	NC score	0.056526 (rank : 479)
Query Neighborhood Hits	378	Target Neighborhood Hits	167	Shared Neighborhood Hits	39
SwissProt Accessions	O15240	Gene names	VGF
Domain Architecture	No domain graphic available
Description	Neurosecretory protein VGF precursor.

WASF1_HUMAN
θ value	θ > 10 (rank : 719)	NC score	0.099380 (rank : 188)
Query Neighborhood Hits	378	Target Neighborhood Hits	260	Shared Neighborhood Hits	89
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

WASF1_MOUSE
θ value	θ > 10 (rank : 720)	NC score	0.100017 (rank : 186)
Query Neighborhood Hits	378	Target Neighborhood Hits	261	Shared Neighborhood Hits	86
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

WASF2_HUMAN
θ value	θ > 10 (rank : 721)	NC score	0.111184 (rank : 133)
Query Neighborhood Hits	378	Target Neighborhood Hits	280	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

WASF2_MOUSE
θ value	θ > 10 (rank : 722)	NC score	0.121379 (rank : 98)
Query Neighborhood Hits	378	Target Neighborhood Hits	315	Shared Neighborhood Hits	107
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

WASF3_HUMAN
θ value	θ > 10 (rank : 723)	NC score	0.075992 (rank : 321)
Query Neighborhood Hits	378	Target Neighborhood Hits	204	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

WASF3_MOUSE
θ value	θ > 10 (rank : 724)	NC score	0.068962 (rank : 362)
Query Neighborhood Hits	378	Target Neighborhood Hits	188	Shared Neighborhood Hits	71
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

WASF4_HUMAN
θ value	θ > 10 (rank : 725)	NC score	0.109333 (rank : 139)
Query Neighborhood Hits	378	Target Neighborhood Hits	282	Shared Neighborhood Hits	103
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

WASIP_HUMAN
θ value	θ > 10 (rank : 726)	NC score	0.197645 (rank : 24)
Query Neighborhood Hits	378	Target Neighborhood Hits	458	Shared Neighborhood Hits	135
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WASIP_MOUSE
θ value	θ > 10 (rank : 727)	NC score	0.179717 (rank : 34)
Query Neighborhood Hits	378	Target Neighborhood Hits	392	Shared Neighborhood Hits	119
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

WASL_HUMAN
θ value	θ > 10 (rank : 728)	NC score	0.123748 (rank : 97)
Query Neighborhood Hits	378	Target Neighborhood Hits	312	Shared Neighborhood Hits	100
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASL_MOUSE
θ value	θ > 10 (rank : 729)	NC score	0.128579 (rank : 87)
Query Neighborhood Hits	378	Target Neighborhood Hits	339	Shared Neighborhood Hits	102
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASP_HUMAN
θ value	θ > 10 (rank : 730)	NC score	0.086259 (rank : 260)
Query Neighborhood Hits	378	Target Neighborhood Hits	195	Shared Neighborhood Hits	69
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

WASP_MOUSE
θ value	θ > 10 (rank : 731)	NC score	0.091481 (rank : 228)
Query Neighborhood Hits	378	Target Neighborhood Hits	223	Shared Neighborhood Hits	76
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

WBP11_HUMAN
θ value	θ > 10 (rank : 732)	NC score	0.144187 (rank : 64)
Query Neighborhood Hits	378	Target Neighborhood Hits	354	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
θ value	θ > 10 (rank : 733)	NC score	0.140134 (rank : 68)
Query Neighborhood Hits	378	Target Neighborhood Hits	362	Shared Neighborhood Hits	92
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

WBS14_HUMAN
θ value	θ > 10 (rank : 734)	NC score	0.099057 (rank : 191)
Query Neighborhood Hits	378	Target Neighborhood Hits	273	Shared Neighborhood Hits	82
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

WBS14_MOUSE
θ value	θ > 10 (rank : 735)	NC score	0.063144 (rank : 403)
Query Neighborhood Hits	378	Target Neighborhood Hits	171	Shared Neighborhood Hits	55
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

WIRE_HUMAN
θ value	θ > 10 (rank : 736)	NC score	0.147966 (rank : 57)
Query Neighborhood Hits	378	Target Neighborhood Hits	329	Shared Neighborhood Hits	104
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

WIRE_MOUSE
θ value	θ > 10 (rank : 737)	NC score	0.136392 (rank : 76)
Query Neighborhood Hits	378	Target Neighborhood Hits	310	Shared Neighborhood Hits	89
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

WNK2_HUMAN
θ value	θ > 10 (rank : 738)	NC score	0.068123 (rank : 373)
Query Neighborhood Hits	378	Target Neighborhood Hits	1407	Shared Neighborhood Hits	175
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

WNK4_HUMAN
θ value	θ > 10 (rank : 739)	NC score	0.052546 (rank : 526)
Query Neighborhood Hits	378	Target Neighborhood Hits	1043	Shared Neighborhood Hits	132
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

YLPM1_HUMAN
θ value	θ > 10 (rank : 740)	NC score	0.104563 (rank : 167)
Query Neighborhood Hits	378	Target Neighborhood Hits	670	Shared Neighborhood Hits	117
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

YLPM1_MOUSE
θ value	θ > 10 (rank : 741)	NC score	0.134770 (rank : 78)
Query Neighborhood Hits	378	Target Neighborhood Hits	505	Shared Neighborhood Hits	124
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ZAN_HUMAN
θ value	θ > 10 (rank : 742)	NC score	0.068420 (rank : 365)
Query Neighborhood Hits	378	Target Neighborhood Hits	679	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ZCHC5_HUMAN
θ value	θ > 10 (rank : 743)	NC score	0.057141 (rank : 469)
Query Neighborhood Hits	378	Target Neighborhood Hits	75	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N8U3	Gene names	ZCCHC5
Domain Architecture
Description	Zinc finger CCHC domain-containing protein 5.

ZN207_HUMAN
θ value	θ > 10 (rank : 744)	NC score	0.114575 (rank : 119)
Query Neighborhood Hits	378	Target Neighborhood Hits	326	Shared Neighborhood Hits	59
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

ZN598_HUMAN
θ value	θ > 10 (rank : 745)	NC score	0.067897 (rank : 375)
Query Neighborhood Hits	378	Target Neighborhood Hits	339	Shared Neighborhood Hits	57
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

ZYX_HUMAN
θ value	θ > 10 (rank : 746)	NC score	0.070345 (rank : 352)
Query Neighborhood Hits	378	Target Neighborhood Hits	387	Shared Neighborhood Hits	79
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

ZYX_MOUSE
θ value	θ > 10 (rank : 747)	NC score	0.069539 (rank : 358)
Query Neighborhood Hits	378	Target Neighborhood Hits	347	Shared Neighborhood Hits	70
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

Hits sorted by NC score

DGKK_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	378	Target Neighborhood Hits	378	Shared Neighborhood Hits	378
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

DGKD_HUMAN
NC score	0.782076 (rank : 2)	θ value	3.28708e-135 (rank : 2)
Query Neighborhood Hits	378	Target Neighborhood Hits	231	Shared Neighborhood Hits	66
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

DGKH_HUMAN
NC score	0.778515 (rank : 3)	θ value	7.84197e-129 (rank : 3)
Query Neighborhood Hits	378	Target Neighborhood Hits	255	Shared Neighborhood Hits	68
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

DGKE_HUMAN
NC score	0.767798 (rank : 4)	θ value	4.55743e-44 (rank : 9)
Query Neighborhood Hits	378	Target Neighborhood Hits	32	Shared Neighborhood Hits	23
SwissProt Accessions	P52429, Q9UKQ3	Gene names	DGKE, DAGK5
Domain Architecture
Description	Diacylglycerol kinase epsilon (EC 2.7.1.107) (Diglyceride kinase epsilon) (DGK-epsilon) (DAG kinase epsilon).

DGKE_MOUSE
NC score	0.766601 (rank : 5)	θ value	1.67352e-46 (rank : 5)
Query Neighborhood Hits	378	Target Neighborhood Hits	30	Shared Neighborhood Hits	20
SwissProt Accessions	Q9R1C6	Gene names	Dgke
Domain Architecture
Description	Diacylglycerol kinase epsilon (EC 2.7.1.107) (Diglyceride kinase epsilon) (DGK-epsilon) (DAG kinase epsilon).

DGKA_HUMAN
NC score	0.739081 (rank : 6)	θ value	1.36902e-48 (rank : 4)
Query Neighborhood Hits	378	Target Neighborhood Hits	151	Shared Neighborhood Hits	41
SwissProt Accessions	P23743, O75481, O75482, O75483	Gene names	DGKA, DAGK, DAGK1
Domain Architecture
Description	Diacylglycerol kinase alpha (EC 2.7.1.107) (Diglyceride kinase alpha) (DGK-alpha) (DAG kinase alpha) (80 kDa diacylglycerol kinase).

DGKA_MOUSE
NC score	0.726448 (rank : 7)	θ value	3.15612e-45 (rank : 8)
Query Neighborhood Hits	378	Target Neighborhood Hits	146	Shared Neighborhood Hits	35
SwissProt Accessions	O88673, Q922X2	Gene names	Dgka, Dagk1
Domain Architecture
Description	Diacylglycerol kinase alpha (EC 2.7.1.107) (Diglyceride kinase alpha) (DGK-alpha) (DAG kinase alpha) (80 kDa diacylglycerol kinase).

DGKG_HUMAN
NC score	0.723012 (rank : 8)	θ value	2.95404e-43 (rank : 10)
Query Neighborhood Hits	378	Target Neighborhood Hits	171	Shared Neighborhood Hits	38
SwissProt Accessions	P49619	Gene names	DGKG, DAGK3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma).

DGKG_MOUSE
NC score	0.721132 (rank : 9)	θ value	4.86918e-46 (rank : 7)
Query Neighborhood Hits	378	Target Neighborhood Hits	188	Shared Neighborhood Hits	41
SwissProt Accessions	Q91WG7	Gene names	Dgkg, Dagk3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma) (88 kDa diacylglycerol kinase).

DGKQ_HUMAN
NC score	0.708476 (rank : 10)	θ value	2.86786e-30 (rank : 14)
Query Neighborhood Hits	378	Target Neighborhood Hits	131	Shared Neighborhood Hits	41
SwissProt Accessions	P52824	Gene names	DGKQ, DAGK4
Domain Architecture
Description	Diacylglycerol kinase theta (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta) (DAG kinase theta).

DGKB_HUMAN
NC score	0.696841 (rank : 11)	θ value	4.86918e-46 (rank : 6)
Query Neighborhood Hits	378	Target Neighborhood Hits	238	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y6T7, O75241, Q75MF9, Q75MU7, Q86UI5, Q86UM9, Q9UQ29	Gene names	DGKB, DAGK2, KIAA0718
Domain Architecture
Description	Diacylglycerol kinase beta (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta) (DAG kinase beta) (90 kDa diacylglycerol kinase).

DGKZ_MOUSE
NC score	0.616796 (rank : 12)	θ value	2.59387e-31 (rank : 12)
Query Neighborhood Hits	378	Target Neighborhood Hits	542	Shared Neighborhood Hits	26
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

DGKZ_HUMAN
NC score	0.612588 (rank : 13)	θ value	3.3877e-31 (rank : 13)
Query Neighborhood Hits	378	Target Neighborhood Hits	551	Shared Neighborhood Hits	23
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

DGKI_HUMAN
NC score	0.605362 (rank : 14)	θ value	6.82597e-32 (rank : 11)
Query Neighborhood Hits	378	Target Neighborhood Hits	609	Shared Neighborhood Hits	30
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

PRP2_MOUSE
NC score	0.240063 (rank : 15)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	378	Target Neighborhood Hits	347	Shared Neighborhood Hits	110
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

MUC7_HUMAN
NC score	0.239390 (rank : 16)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	378	Target Neighborhood Hits	538	Shared Neighborhood Hits	159
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

PRG4_HUMAN
NC score	0.235673 (rank : 17)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	378	Target Neighborhood Hits	764	Shared Neighborhood Hits	162
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRR12_HUMAN
NC score	0.226032 (rank : 18)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	378	Target Neighborhood Hits	460	Shared Neighborhood Hits	156
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

SPRR3_HUMAN
NC score	0.220293 (rank : 19)	θ value	2.61198e-07 (rank : 22)
Query Neighborhood Hits	378	Target Neighborhood Hits	102	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

PRG4_MOUSE
NC score	0.213031 (rank : 20)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	378	Target Neighborhood Hits	624	Shared Neighborhood Hits	151
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

CK024_HUMAN
NC score	0.205134 (rank : 21)	θ value	9.29e-05 (rank : 32)
Query Neighborhood Hits	378	Target Neighborhood Hits	408	Shared Neighborhood Hits	96
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

SPRR3_MOUSE
NC score	0.203690 (rank : 22)	θ value	0.000786445 (rank : 52)
Query Neighborhood Hits	378	Target Neighborhood Hits	106	Shared Neighborhood Hits	36
SwissProt Accessions	O09116	Gene names	Sprr3
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta).

CDN1C_HUMAN
NC score	0.197968 (rank : 23)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	378	Target Neighborhood Hits	168	Shared Neighborhood Hits	85
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

WASIP_HUMAN
NC score	0.197645 (rank : 24)	θ value	θ > 10 (rank : 726)
Query Neighborhood Hits	378	Target Neighborhood Hits	458	Shared Neighborhood Hits	135
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

PRP1_HUMAN
NC score	0.193006 (rank : 25)	θ value	θ > 10 (rank : 593)
Query Neighborhood Hits	378	Target Neighborhood Hits	385	Shared Neighborhood Hits	103
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

SPR1B_MOUSE
NC score	0.188169 (rank : 26)	θ value	1.09485e-13 (rank : 16)
Query Neighborhood Hits	378	Target Neighborhood Hits	395	Shared Neighborhood Hits	61
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

PRB3_HUMAN
NC score	0.187808 (rank : 27)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	378	Target Neighborhood Hits	318	Shared Neighborhood Hits	93
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

MDC1_HUMAN
NC score	0.187408 (rank : 28)	θ value	3.77169e-06 (rank : 24)
Query Neighborhood Hits	378	Target Neighborhood Hits	1446	Shared Neighborhood Hits	167
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PRB4S_HUMAN
NC score	0.183314 (rank : 29)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	378	Target Neighborhood Hits	330	Shared Neighborhood Hits	96
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

CJ078_MOUSE
NC score	0.182883 (rank : 30)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	378	Target Neighborhood Hits	559	Shared Neighborhood Hits	121
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

GSCR1_HUMAN
NC score	0.182245 (rank : 31)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	378	Target Neighborhood Hits	674	Shared Neighborhood Hits	155
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

CN155_HUMAN
NC score	0.182119 (rank : 32)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	378	Target Neighborhood Hits	385	Shared Neighborhood Hits	108
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

MDC1_MOUSE
NC score	0.181601 (rank : 33)	θ value	1.99992e-07 (rank : 21)
Query Neighborhood Hits	378	Target Neighborhood Hits	998	Shared Neighborhood Hits	132
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

WASIP_MOUSE
NC score	0.179717 (rank : 34)	θ value	θ > 10 (rank : 727)
Query Neighborhood Hits	378	Target Neighborhood Hits	392	Shared Neighborhood Hits	119
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

SPR1A_MOUSE
NC score	0.178800 (rank : 35)	θ value	4.76016e-09 (rank : 19)
Query Neighborhood Hits	378	Target Neighborhood Hits	343	Shared Neighborhood Hits	49
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

SRRM1_MOUSE
NC score	0.178369 (rank : 36)	θ value	2.36792 (rank : 256)
Query Neighborhood Hits	378	Target Neighborhood Hits	966	Shared Neighborhood Hits	153
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM1_HUMAN
NC score	0.176809 (rank : 37)	θ value	θ > 10 (rank : 674)
Query Neighborhood Hits	378	Target Neighborhood Hits	690	Shared Neighborhood Hits	131
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

TAF4_HUMAN
NC score	0.174893 (rank : 38)	θ value	θ > 10 (rank : 691)
Query Neighborhood Hits	378	Target Neighborhood Hits	687	Shared Neighborhood Hits	133
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

RAPH1_HUMAN
NC score	0.169963 (rank : 39)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	378	Target Neighborhood Hits	593	Shared Neighborhood Hits	158
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

BASP_MOUSE
NC score	0.166365 (rank : 40)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	378	Target Neighborhood Hits	260	Shared Neighborhood Hits	67
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

SELPL_MOUSE
NC score	0.165948 (rank : 41)	θ value	8.40245e-06 (rank : 26)
Query Neighborhood Hits	378	Target Neighborhood Hits	588	Shared Neighborhood Hits	107
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

NACAM_MOUSE
NC score	0.165294 (rank : 42)	θ value	0.000158464 (rank : 37)
Query Neighborhood Hits	378	Target Neighborhood Hits	1866	Shared Neighborhood Hits	204
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

OGFR_HUMAN
NC score	0.161840 (rank : 43)	θ value	7.34386e-10 (rank : 18)
Query Neighborhood Hits	378	Target Neighborhood Hits	1582	Shared Neighborhood Hits	171
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

SON_MOUSE
NC score	0.160312 (rank : 44)	θ value	0.00509761 (rank : 73)
Query Neighborhood Hits	378	Target Neighborhood Hits	957	Shared Neighborhood Hits	141
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

MADCA_HUMAN
NC score	0.159134 (rank : 45)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	378	Target Neighborhood Hits	221	Shared Neighborhood Hits	84
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

SELV_HUMAN
NC score	0.158487 (rank : 46)	θ value	θ > 10 (rank : 634)
Query Neighborhood Hits	378	Target Neighborhood Hits	118	Shared Neighborhood Hits	57
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

GGN_MOUSE
NC score	0.157597 (rank : 47)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	378	Target Neighborhood Hits	311	Shared Neighborhood Hits	106
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

MUC2_HUMAN
NC score	0.156428 (rank : 48)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	378	Target Neighborhood Hits	906	Shared Neighborhood Hits	158
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PCLO_HUMAN
NC score	0.155308 (rank : 49)	θ value	0.0113563 (rank : 81)
Query Neighborhood Hits	378	Target Neighborhood Hits	2046	Shared Neighborhood Hits	215
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SF3A2_MOUSE
NC score	0.153551 (rank : 50)	θ value	θ > 10 (rank : 641)
Query Neighborhood Hits	378	Target Neighborhood Hits	247	Shared Neighborhood Hits	86
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

PCLO_MOUSE
NC score	0.153398 (rank : 51)	θ value	0.000121331 (rank : 35)
Query Neighborhood Hits	378	Target Neighborhood Hits	2275	Shared Neighborhood Hits	214
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

MBD6_HUMAN
NC score	0.151181 (rank : 52)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	378	Target Neighborhood Hits	349	Shared Neighborhood Hits	92
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

FA47B_HUMAN
NC score	0.150841 (rank : 53)	θ value	9.92553e-07 (rank : 23)
Query Neighborhood Hits	378	Target Neighborhood Hits	431	Shared Neighborhood Hits	72
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

TARSH_HUMAN
NC score	0.150591 (rank : 54)	θ value	0.0431538 (rank : 104)
Query Neighborhood Hits	378	Target Neighborhood Hits	768	Shared Neighborhood Hits	110
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

ENAH_MOUSE
NC score	0.150508 (rank : 55)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	378	Target Neighborhood Hits	919	Shared Neighborhood Hits	170
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

SON_HUMAN
NC score	0.149916 (rank : 56)	θ value	1.09739e-05 (rank : 27)
Query Neighborhood Hits	378	Target Neighborhood Hits	1568	Shared Neighborhood Hits	173
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

WIRE_HUMAN
NC score	0.147966 (rank : 57)	θ value	θ > 10 (rank : 736)
Query Neighborhood Hits	378	Target Neighborhood Hits	329	Shared Neighborhood Hits	104
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

FA47A_HUMAN
NC score	0.147730 (rank : 58)	θ value	0.00102713 (rank : 54)
Query Neighborhood Hits	378	Target Neighborhood Hits	451	Shared Neighborhood Hits	59
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

SF3A2_HUMAN
NC score	0.147562 (rank : 59)	θ value	θ > 10 (rank : 640)
Query Neighborhood Hits	378	Target Neighborhood Hits	263	Shared Neighborhood Hits	90
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

BSN_MOUSE
NC score	0.147148 (rank : 60)	θ value	0.0252991 (rank : 89)
Query Neighborhood Hits	378	Target Neighborhood Hits	2057	Shared Neighborhood Hits	206
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

SPR1A_HUMAN
NC score	0.145210 (rank : 61)	θ value	0.0431538 (rank : 103)
Query Neighborhood Hits	378	Target Neighborhood Hits	136	Shared Neighborhood Hits	25
SwissProt Accessions	P35321, Q9UDG4	Gene names	SPRR1A
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein IA) (SPR-IA) (SPRK) (19 kDa pancornulin).

BSN_HUMAN
NC score	0.145174 (rank : 62)	θ value	4.03905 (rank : 288)
Query Neighborhood Hits	378	Target Neighborhood Hits	1537	Shared Neighborhood Hits	178
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

GGN_HUMAN
NC score	0.144214 (rank : 63)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	378	Target Neighborhood Hits	269	Shared Neighborhood Hits	85
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

WBP11_HUMAN
NC score	0.144187 (rank : 64)	θ value	θ > 10 (rank : 732)
Query Neighborhood Hits	378	Target Neighborhood Hits	354	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

SPR1B_HUMAN
NC score	0.141703 (rank : 65)	θ value	0.0961366 (rank : 121)
Query Neighborhood Hits	378	Target Neighborhood Hits	102	Shared Neighborhood Hits	16
SwissProt Accessions	P22528, P22529, P22530, Q5T524	Gene names	SPRR1B
Domain Architecture	No domain graphic available
Description	Cornifin B (Small proline-rich protein IB) (SPR-IB) (14.9 kDa pancornulin).

CN032_MOUSE
NC score	0.141696 (rank : 66)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	378	Target Neighborhood Hits	233	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CN032_HUMAN
NC score	0.140698 (rank : 67)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	378	Target Neighborhood Hits	267	Shared Neighborhood Hits	77
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

WBP11_MOUSE
NC score	0.140134 (rank : 68)	θ value	θ > 10 (rank : 733)
Query Neighborhood Hits	378	Target Neighborhood Hits	362	Shared Neighborhood Hits	92
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

ATN1_HUMAN
NC score	0.140044 (rank : 69)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	378	Target Neighborhood Hits	676	Shared Neighborhood Hits	139
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BASP_HUMAN
NC score	0.139865 (rank : 70)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	378	Target Neighborhood Hits	321	Shared Neighborhood Hits	75
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CDN1C_MOUSE
NC score	0.139127 (rank : 71)	θ value	0.000602161 (rank : 47)
Query Neighborhood Hits	378	Target Neighborhood Hits	161	Shared Neighborhood Hits	49
SwissProt Accessions	P49919	Gene names	Cdkn1c, Kip2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CS016_HUMAN
NC score	0.139036 (rank : 72)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	378	Target Neighborhood Hits	310	Shared Neighborhood Hits	86
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

MLL2_HUMAN
NC score	0.138992 (rank : 73)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	378	Target Neighborhood Hits	1788	Shared Neighborhood Hits	200
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

SRRM2_HUMAN
NC score	0.138672 (rank : 74)	θ value	θ > 10 (rank : 675)
Query Neighborhood Hits	378	Target Neighborhood Hits	1296	Shared Neighborhood Hits	165
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SET1A_HUMAN
NC score	0.137930 (rank : 75)	θ value	θ > 10 (rank : 635)
Query Neighborhood Hits	378	Target Neighborhood Hits	690	Shared Neighborhood Hits	137
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

WIRE_MOUSE
NC score	0.136392 (rank : 76)	θ value	θ > 10 (rank : 737)
Query Neighborhood Hits	378	Target Neighborhood Hits	310	Shared Neighborhood Hits	89
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

GRP3_HUMAN
NC score	0.136028 (rank : 77)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	378	Target Neighborhood Hits	131	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

YLPM1_MOUSE
NC score	0.134770 (rank : 78)	θ value	θ > 10 (rank : 741)
Query Neighborhood Hits	378	Target Neighborhood Hits	505	Shared Neighborhood Hits	124
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

RERE_HUMAN
NC score	0.134462 (rank : 79)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	378	Target Neighborhood Hits	779	Shared Neighborhood Hits	147
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

MLL4_HUMAN
NC score	0.133339 (rank : 80)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	378	Target Neighborhood Hits	722	Shared Neighborhood Hits	145
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

RASF1_MOUSE
NC score	0.132731 (rank : 81)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	378	Target Neighborhood Hits	74	Shared Neighborhood Hits	31
SwissProt Accessions	Q99MK9, Q9WUF5	Gene names	Rassf1
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1 (Protein 123F2).

BAT2_HUMAN
NC score	0.132674 (rank : 82)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	378	Target Neighborhood Hits	931	Shared Neighborhood Hits	162
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

PRRT3_HUMAN
NC score	0.131985 (rank : 83)	θ value	0.000786445 (rank : 51)
Query Neighborhood Hits	378	Target Neighborhood Hits	998	Shared Neighborhood Hits	137
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SPR2H_MOUSE
NC score	0.131924 (rank : 84)	θ value	θ > 10 (rank : 666)
Query Neighborhood Hits	378	Target Neighborhood Hits	82	Shared Neighborhood Hits	28
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

PRR13_HUMAN
NC score	0.131193 (rank : 85)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	378	Target Neighborhood Hits	105	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

ALEX_HUMAN
NC score	0.129763 (rank : 86)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	378	Target Neighborhood Hits	361	Shared Neighborhood Hits	95
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

WASL_MOUSE
NC score	0.128579 (rank : 87)	θ value	θ > 10 (rank : 729)
Query Neighborhood Hits	378	Target Neighborhood Hits	339	Shared Neighborhood Hits	102
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

CCNK_MOUSE
NC score	0.128166 (rank : 88)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	378	Target Neighborhood Hits	350	Shared Neighborhood Hits	110
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

MNT_HUMAN
NC score	0.128101 (rank : 89)	θ value	1.38821 (rank : 225)
Query Neighborhood Hits	378	Target Neighborhood Hits	496	Shared Neighborhood Hits	97
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MUC1_HUMAN
NC score	0.128051 (rank : 90)	θ value	1.74796e-11 (rank : 17)
Query Neighborhood Hits	378	Target Neighborhood Hits	975	Shared Neighborhood Hits	112
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

RERE_MOUSE
NC score	0.126736 (rank : 91)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	378	Target Neighborhood Hits	785	Shared Neighborhood Hits	150
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

NCOA6_HUMAN
NC score	0.125913 (rank : 92)	θ value	0.00134147 (rank : 58)
Query Neighborhood Hits	378	Target Neighborhood Hits	1202	Shared Neighborhood Hits	144
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

K1802_HUMAN
NC score	0.125652 (rank : 93)	θ value	0.0431538 (rank : 99)
Query Neighborhood Hits	378	Target Neighborhood Hits	1378	Shared Neighborhood Hits	162
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

RGS3_MOUSE
NC score	0.125223 (rank : 94)	θ value	2.44474e-05 (rank : 30)
Query Neighborhood Hits	378	Target Neighborhood Hits	1621	Shared Neighborhood Hits	173
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

STAC_MOUSE
NC score	0.125202 (rank : 95)	θ value	θ > 10 (rank : 679)
Query Neighborhood Hits	378	Target Neighborhood Hits	268	Shared Neighborhood Hits	44
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

SRRM2_MOUSE
NC score	0.124957 (rank : 96)	θ value	5.27518 (rank : 323)
Query Neighborhood Hits	378	Target Neighborhood Hits	1470	Shared Neighborhood Hits	169
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

WASL_HUMAN
NC score	0.123748 (rank : 97)	θ value	θ > 10 (rank : 728)
Query Neighborhood Hits	378	Target Neighborhood Hits	312	Shared Neighborhood Hits	100
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASF2_MOUSE
NC score	0.121379 (rank : 98)	θ value	θ > 10 (rank : 722)
Query Neighborhood Hits	378	Target Neighborhood Hits	315	Shared Neighborhood Hits	107
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

MARCS_MOUSE
NC score	0.121364 (rank : 99)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	378	Target Neighborhood Hits	227	Shared Neighborhood Hits	65
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

STAC_HUMAN
NC score	0.120582 (rank : 100)	θ value	θ > 10 (rank : 678)
Query Neighborhood Hits	378	Target Neighborhood Hits	276	Shared Neighborhood Hits	43
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

MNT_MOUSE
NC score	0.120289 (rank : 101)	θ value	3.0926 (rank : 276)
Query Neighborhood Hits	378	Target Neighborhood Hits	432	Shared Neighborhood Hits	95
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

SMR1_MOUSE
NC score	0.120215 (rank : 102)	θ value	θ > 10 (rank : 650)
Query Neighborhood Hits	378	Target Neighborhood Hits	103	Shared Neighborhood Hits	44
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

CO039_MOUSE
NC score	0.120210 (rank : 103)	θ value	0.0252991 (rank : 91)
Query Neighborhood Hits	378	Target Neighborhood Hits	445	Shared Neighborhood Hits	100
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

MUC1_MOUSE
NC score	0.120003 (rank : 104)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	378	Target Neighborhood Hits	388	Shared Neighborhood Hits	52
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

PELP1_HUMAN
NC score	0.119006 (rank : 105)	θ value	θ > 10 (rank : 568)
Query Neighborhood Hits	378	Target Neighborhood Hits	596	Shared Neighborhood Hits	119
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

NCOA6_MOUSE
NC score	0.118877 (rank : 106)	θ value	0.279714 (rank : 156)
Query Neighborhood Hits	378	Target Neighborhood Hits	1076	Shared Neighborhood Hits	131
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

BAT3_MOUSE
NC score	0.118808 (rank : 107)	θ value	4.03905 (rank : 286)
Query Neighborhood Hits	378	Target Neighborhood Hits	518	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

SPR2D_MOUSE
NC score	0.118760 (rank : 108)	θ value	θ > 10 (rank : 659)
Query Neighborhood Hits	378	Target Neighborhood Hits	61	Shared Neighborhood Hits	20
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

IASPP_MOUSE
NC score	0.118505 (rank : 109)	θ value	4.92598e-06 (rank : 25)
Query Neighborhood Hits	378	Target Neighborhood Hits	1024	Shared Neighborhood Hits	101
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

SFPQ_MOUSE
NC score	0.117692 (rank : 110)	θ value	θ > 10 (rank : 643)
Query Neighborhood Hits	378	Target Neighborhood Hits	958	Shared Neighborhood Hits	140
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

CPSF6_MOUSE
NC score	0.116698 (rank : 111)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	378	Target Neighborhood Hits	356	Shared Neighborhood Hits	86
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

BAG3_MOUSE
NC score	0.116348 (rank : 112)	θ value	0.163984 (rank : 127)
Query Neighborhood Hits	378	Target Neighborhood Hits	513	Shared Neighborhood Hits	106
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

K1802_MOUSE
NC score	0.116040 (rank : 113)	θ value	3.19293e-05 (rank : 31)
Query Neighborhood Hits	378	Target Neighborhood Hits	1596	Shared Neighborhood Hits	155
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

SFPQ_HUMAN
NC score	0.115854 (rank : 114)	θ value	θ > 10 (rank : 642)
Query Neighborhood Hits	378	Target Neighborhood Hits	986	Shared Neighborhood Hits	156
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SPR2D_HUMAN
NC score	0.115377 (rank : 115)	θ value	θ > 10 (rank : 658)
Query Neighborhood Hits	378	Target Neighborhood Hits	30	Shared Neighborhood Hits	10
SwissProt Accessions	P22532, Q5T523, Q96RM3	Gene names	SPRR2D
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D (SPR-2D) (Small proline-rich protein II) (SPR-II).

ASPP1_MOUSE
NC score	0.115325 (rank : 116)	θ value	2.44474e-05 (rank : 29)
Query Neighborhood Hits	378	Target Neighborhood Hits	1244	Shared Neighborhood Hits	111
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CPSF6_HUMAN
NC score	0.114795 (rank : 117)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	378	Target Neighborhood Hits	359	Shared Neighborhood Hits	87
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

IASPP_HUMAN
NC score	0.114597 (rank : 118)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	378	Target Neighborhood Hits	688	Shared Neighborhood Hits	94
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ZN207_HUMAN
NC score	0.114575 (rank : 119)	θ value	θ > 10 (rank : 744)
Query Neighborhood Hits	378	Target Neighborhood Hits	326	Shared Neighborhood Hits	59
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

T22D2_HUMAN
NC score	0.113587 (rank : 120)	θ value	4.03905 (rank : 297)
Query Neighborhood Hits	378	Target Neighborhood Hits	250	Shared Neighborhood Hits	60
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

EP300_HUMAN
NC score	0.113435 (rank : 121)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	378	Target Neighborhood Hits	821	Shared Neighborhood Hits	150
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

TMAP1_HUMAN
NC score	0.113123 (rank : 122)	θ value	θ > 10 (rank : 704)
Query Neighborhood Hits	378	Target Neighborhood Hits	140	Shared Neighborhood Hits	49
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

UN13A_HUMAN
NC score	0.112757 (rank : 123)	θ value	θ > 10 (rank : 707)
Query Neighborhood Hits	378	Target Neighborhood Hits	285	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

PELP1_MOUSE
NC score	0.112337 (rank : 124)	θ value	θ > 10 (rank : 569)
Query Neighborhood Hits	378	Target Neighborhood Hits	709	Shared Neighborhood Hits	119
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

BAT3_HUMAN
NC score	0.112316 (rank : 125)	θ value	0.47712 (rank : 165)
Query Neighborhood Hits	378	Target Neighborhood Hits	490	Shared Neighborhood Hits	91
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

PO121_HUMAN
NC score	0.112029 (rank : 126)	θ value	θ > 10 (rank : 582)
Query Neighborhood Hits	378	Target Neighborhood Hits	344	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

DAPP1_MOUSE
NC score	0.112006 (rank : 127)	θ value	0.000461057 (rank : 46)
Query Neighborhood Hits	378	Target Neighborhood Hits	225	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

CBP_HUMAN
NC score	0.111675 (rank : 128)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	378	Target Neighborhood Hits	941	Shared Neighborhood Hits	159
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

SPR2G_MOUSE
NC score	0.111513 (rank : 129)	θ value	θ > 10 (rank : 665)
Query Neighborhood Hits	378	Target Neighborhood Hits	53	Shared Neighborhood Hits	15
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

MARCS_HUMAN
NC score	0.111381 (rank : 130)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	378	Target Neighborhood Hits	204	Shared Neighborhood Hits	58
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

SYN1_HUMAN
NC score	0.111249 (rank : 131)	θ value	θ > 10 (rank : 682)
Query Neighborhood Hits	378	Target Neighborhood Hits	419	Shared Neighborhood Hits	120
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

TCOF_MOUSE
NC score	0.111184 (rank : 132)	θ value	θ > 10 (rank : 696)
Query Neighborhood Hits	378	Target Neighborhood Hits	471	Shared Neighborhood Hits	83
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

WASF2_HUMAN
NC score	0.111184 (rank : 133)	θ value	θ > 10 (rank : 721)
Query Neighborhood Hits	378	Target Neighborhood Hits	280	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

SPR2E_MOUSE
NC score	0.110913 (rank : 134)	θ value	θ > 10 (rank : 661)
Query Neighborhood Hits	378	Target Neighborhood Hits	45	Shared Neighborhood Hits	14
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

UN13B_HUMAN
NC score	0.109900 (rank : 135)	θ value	5.27518 (rank : 327)
Query Neighborhood Hits	378	Target Neighborhood Hits	217	Shared Neighborhood Hits	42
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

BCL9_HUMAN
NC score	0.109813 (rank : 136)	θ value	0.0252991 (rank : 88)
Query Neighborhood Hits	378	Target Neighborhood Hits	1008	Shared Neighborhood Hits	121
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

MLL3_HUMAN
NC score	0.109678 (rank : 137)	θ value	0.000121331 (rank : 34)
Query Neighborhood Hits	378	Target Neighborhood Hits	1644	Shared Neighborhood Hits	147
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

BAT2_MOUSE
NC score	0.109437 (rank : 138)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	378	Target Neighborhood Hits	947	Shared Neighborhood Hits	165
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

WASF4_HUMAN
NC score	0.109333 (rank : 139)	θ value	θ > 10 (rank : 725)
Query Neighborhood Hits	378	Target Neighborhood Hits	282	Shared Neighborhood Hits	103
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

DAPP1_HUMAN
NC score	0.109221 (rank : 140)	θ value	0.00175202 (rank : 60)
Query Neighborhood Hits	378	Target Neighborhood Hits	227	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

SPR2B_HUMAN
NC score	0.109032 (rank : 141)	θ value	θ > 10 (rank : 656)
Query Neighborhood Hits	378	Target Neighborhood Hits	24	Shared Neighborhood Hits	8
SwissProt Accessions	P35325, Q5T528	Gene names	SPRR2B
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B (SPR-2B).

PS1C2_HUMAN
NC score	0.108858 (rank : 142)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	378	Target Neighborhood Hits	66	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UIG4	Gene names	PSORS1C2, C6orf17, SPR1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein precursor (SPR1 protein).

CO039_HUMAN
NC score	0.108683 (rank : 143)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	378	Target Neighborhood Hits	264	Shared Neighborhood Hits	71
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

PI5PA_HUMAN
NC score	0.108501 (rank : 144)	θ value	0.0961366 (rank : 119)
Query Neighborhood Hits	378	Target Neighborhood Hits	749	Shared Neighborhood Hits	126
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

BRD4_MOUSE
NC score	0.108406 (rank : 145)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	378	Target Neighborhood Hits	845	Shared Neighborhood Hits	139
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

DP13B_HUMAN
NC score	0.108263 (rank : 146)	θ value	0.00228821 (rank : 65)
Query Neighborhood Hits	378	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NEU8, Q8N4R7, Q9NVL2	Gene names	DIP13B, APPL2
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 beta (Dip13 beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2).

SPR2I_MOUSE
NC score	0.108188 (rank : 147)	θ value	θ > 10 (rank : 667)
Query Neighborhood Hits	378	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

STAC3_HUMAN
NC score	0.107943 (rank : 148)	θ value	θ > 10 (rank : 676)
Query Neighborhood Hits	378	Target Neighborhood Hits	228	Shared Neighborhood Hits	41
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

PKHA1_HUMAN
NC score	0.107763 (rank : 149)	θ value	0.163984 (rank : 136)
Query Neighborhood Hits	378	Target Neighborhood Hits	127	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

SFR15_HUMAN
NC score	0.107686 (rank : 150)	θ value	θ > 10 (rank : 644)
Query Neighborhood Hits	378	Target Neighborhood Hits	368	Shared Neighborhood Hits	80
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

STAC3_MOUSE
NC score	0.107290 (rank : 151)	θ value	θ > 10 (rank : 677)
Query Neighborhood Hits	378	Target Neighborhood Hits	232	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

LR37A_HUMAN
NC score	0.107265 (rank : 152)	θ value	0.00509761 (rank : 71)
Query Neighborhood Hits	378	Target Neighborhood Hits	720	Shared Neighborhood Hits	95
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

FMNL_HUMAN
NC score	0.107133 (rank : 153)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	378	Target Neighborhood Hits	529	Shared Neighborhood Hits	121
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

DP13B_MOUSE
NC score	0.106562 (rank : 154)	θ value	0.00298849 (rank : 66)
Query Neighborhood Hits	378	Target Neighborhood Hits	58	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K3G9, Q99LT7	Gene names	Dip13b, Appl2, Dip3b
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 beta (Dip13 beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2).

NOLC1_HUMAN
NC score	0.106284 (rank : 155)	θ value	θ > 10 (rank : 557)
Query Neighborhood Hits	378	Target Neighborhood Hits	452	Shared Neighborhood Hits	75
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

PCQAP_HUMAN
NC score	0.106241 (rank : 156)	θ value	θ > 10 (rank : 562)
Query Neighborhood Hits	378	Target Neighborhood Hits	549	Shared Neighborhood Hits	100
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

BAG3_HUMAN
NC score	0.105758 (rank : 157)	θ value	8.99809 (rank : 358)
Query Neighborhood Hits	378	Target Neighborhood Hits	314	Shared Neighborhood Hits	78
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

SMR3A_HUMAN
NC score	0.105689 (rank : 158)	θ value	θ > 10 (rank : 651)
Query Neighborhood Hits	378	Target Neighborhood Hits	93	Shared Neighborhood Hits	34
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

AMPH_HUMAN
NC score	0.105459 (rank : 159)	θ value	0.00228821 (rank : 64)
Query Neighborhood Hits	378	Target Neighborhood Hits	455	Shared Neighborhood Hits	66
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

STAT2_MOUSE
NC score	0.105414 (rank : 160)	θ value	5.8054e-15 (rank : 15)
Query Neighborhood Hits	378	Target Neighborhood Hits	175	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

UN13B_MOUSE
NC score	0.105159 (rank : 161)	θ value	2.36792 (rank : 260)
Query Neighborhood Hits	378	Target Neighborhood Hits	210	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

PRR13_MOUSE
NC score	0.104951 (rank : 162)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	378	Target Neighborhood Hits	54	Shared Neighborhood Hits	21
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

SPR2F_MOUSE
NC score	0.104923 (rank : 163)	θ value	θ > 10 (rank : 663)
Query Neighborhood Hits	378	Target Neighborhood Hits	43	Shared Neighborhood Hits	15
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

ASPP1_HUMAN
NC score	0.104900 (rank : 164)	θ value	0.21417 (rank : 139)
Query Neighborhood Hits	378	Target Neighborhood Hits	956	Shared Neighborhood Hits	89
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

PDZD8_HUMAN
NC score	0.104707 (rank : 165)	θ value	θ > 10 (rank : 567)
Query Neighborhood Hits	378	Target Neighborhood Hits	185	Shared Neighborhood Hits	42
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PKHA1_MOUSE
NC score	0.104570 (rank : 166)	θ value	0.21417 (rank : 146)
Query Neighborhood Hits	378	Target Neighborhood Hits	120	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

YLPM1_HUMAN
NC score	0.104563 (rank : 167)	θ value	θ > 10 (rank : 740)
Query Neighborhood Hits	378	Target Neighborhood Hits	670	Shared Neighborhood Hits	117
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

CBP_MOUSE
NC score	0.104472 (rank : 168)	θ value	6.88961 (rank : 334)
Query Neighborhood Hits	378	Target Neighborhood Hits	1051	Shared Neighborhood Hits	145
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

SELPL_HUMAN
NC score	0.103963 (rank : 169)	θ value	θ > 10 (rank : 633)
Query Neighborhood Hits	378	Target Neighborhood Hits	68	Shared Neighborhood Hits	24
SwissProt Accessions	Q14242, Q12775	Gene names	SELPLG
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand) (CD162 antigen).

FMN2_HUMAN
NC score	0.103644 (rank : 170)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	378	Target Neighborhood Hits	484	Shared Neighborhood Hits	99
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

MLL3_MOUSE
NC score	0.103189 (rank : 171)	θ value	0.00390308 (rank : 70)
Query Neighborhood Hits	378	Target Neighborhood Hits	1399	Shared Neighborhood Hits	139
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NFH_MOUSE
NC score	0.102940 (rank : 172)	θ value	1.80886e-08 (rank : 20)
Query Neighborhood Hits	378	Target Neighborhood Hits	2247	Shared Neighborhood Hits	189
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SYN1_MOUSE
NC score	0.102547 (rank : 173)	θ value	θ > 10 (rank : 683)
Query Neighborhood Hits	378	Target Neighborhood Hits	363	Shared Neighborhood Hits	105
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

CABIN_HUMAN
NC score	0.102484 (rank : 174)	θ value	0.813845 (rank : 188)
Query Neighborhood Hits	378	Target Neighborhood Hits	490	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

MILK1_MOUSE
NC score	0.101999 (rank : 175)	θ value	0.279714 (rank : 154)
Query Neighborhood Hits	378	Target Neighborhood Hits	788	Shared Neighborhood Hits	132
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

PO121_MOUSE
NC score	0.101697 (rank : 176)	θ value	θ > 10 (rank : 583)
Query Neighborhood Hits	378	Target Neighborhood Hits	345	Shared Neighborhood Hits	69
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

BCL9_MOUSE
NC score	0.101572 (rank : 177)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	378	Target Neighborhood Hits	770	Shared Neighborhood Hits	110
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CHIO_MOUSE
NC score	0.101421 (rank : 178)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	378	Target Neighborhood Hits	130	Shared Neighborhood Hits	38
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CIC_HUMAN
NC score	0.100837 (rank : 179)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	378	Target Neighborhood Hits	992	Shared Neighborhood Hits	146
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SYNJ1_HUMAN
NC score	0.100721 (rank : 180)	θ value	θ > 10 (rank : 685)
Query Neighborhood Hits	378	Target Neighborhood Hits	498	Shared Neighborhood Hits	128
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SPR2A_HUMAN
NC score	0.100610 (rank : 181)	θ value	θ > 10 (rank : 655)
Query Neighborhood Hits	378	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	P35326	Gene names	SPRR2A
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2A (SPR-2A) (2-1).

SHAN1_HUMAN
NC score	0.100391 (rank : 182)	θ value	θ > 10 (rank : 647)
Query Neighborhood Hits	378	Target Neighborhood Hits	1041	Shared Neighborhood Hits	140
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

MAP4_MOUSE
NC score	0.100357 (rank : 183)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	378	Target Neighborhood Hits	409	Shared Neighborhood Hits	80
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MAGE1_HUMAN
NC score	0.100243 (rank : 184)	θ value	0.00175202 (rank : 63)
Query Neighborhood Hits	378	Target Neighborhood Hits	1389	Shared Neighborhood Hits	158
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

K1543_HUMAN
NC score	0.100236 (rank : 185)	θ value	0.163984 (rank : 133)
Query Neighborhood Hits	378	Target Neighborhood Hits	435	Shared Neighborhood Hits	70
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

WASF1_MOUSE
NC score	0.100017 (rank : 186)	θ value	θ > 10 (rank : 720)
Query Neighborhood Hits	378	Target Neighborhood Hits	261	Shared Neighborhood Hits	86
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

SHAN2_MOUSE
NC score	0.099969 (rank : 187)	θ value	4.03905 (rank : 295)
Query Neighborhood Hits	378	Target Neighborhood Hits	446	Shared Neighborhood Hits	62
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

WASF1_HUMAN
NC score	0.099380 (rank : 188)	θ value	θ > 10 (rank : 719)
Query Neighborhood Hits	378	Target Neighborhood Hits	260	Shared Neighborhood Hits	89
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

CIZ1_HUMAN
NC score	0.099254 (rank : 189)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	378	Target Neighborhood Hits	359	Shared Neighborhood Hits	70
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

VCX3_HUMAN
NC score	0.099100 (rank : 190)	θ value	θ > 10 (rank : 715)
Query Neighborhood Hits	378	Target Neighborhood Hits	105	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

WBS14_HUMAN
NC score	0.099057 (rank : 191)	θ value	θ > 10 (rank : 734)
Query Neighborhood Hits	378	Target Neighborhood Hits	273	Shared Neighborhood Hits	82
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

SPR2E_HUMAN
NC score	0.098833 (rank : 192)	θ value	θ > 10 (rank : 660)
Query Neighborhood Hits	378	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

SNPC4_HUMAN
NC score	0.098700 (rank : 193)	θ value	0.00509761 (rank : 72)
Query Neighborhood Hits	378	Target Neighborhood Hits	589	Shared Neighborhood Hits	80
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

CHIO_HUMAN
NC score	0.098432 (rank : 194)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	378	Target Neighborhood Hits	220	Shared Neighborhood Hits	41
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

SYNJ1_MOUSE
NC score	0.098069 (rank : 195)	θ value	θ > 10 (rank : 686)
Query Neighborhood Hits	378	Target Neighborhood Hits	516	Shared Neighborhood Hits	121
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

PCQAP_MOUSE
NC score	0.098018 (rank : 196)	θ value	θ > 10 (rank : 563)
Query Neighborhood Hits	378	Target Neighborhood Hits	506	Shared Neighborhood Hits	91
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

SPR2G_HUMAN
NC score	0.097841 (rank : 197)	θ value	θ > 10 (rank : 664)
Query Neighborhood Hits	378	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYE4	Gene names	SPRR2G
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G (SPR-2G).

AFF1_HUMAN
NC score	0.097667 (rank : 198)	θ value	0.365318 (rank : 158)
Query Neighborhood Hits	378	Target Neighborhood Hits	506	Shared Neighborhood Hits	86
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

MAP4_HUMAN
NC score	0.097474 (rank : 199)	θ value	8.99809 (rank : 366)
Query Neighborhood Hits	378	Target Neighborhood Hits	428	Shared Neighborhood Hits	73
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

CHIN_HUMAN
NC score	0.097339 (rank : 200)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	378	Target Neighborhood Hits	227	Shared Neighborhood Hits	39
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

ALEX_MOUSE
NC score	0.097132 (rank : 201)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	378	Target Neighborhood Hits	197	Shared Neighborhood Hits	65
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

FGD1_HUMAN
NC score	0.096455 (rank : 202)	θ value	0.21417 (rank : 141)
Query Neighborhood Hits	378	Target Neighborhood Hits	367	Shared Neighborhood Hits	85
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

SHAN2_HUMAN
NC score	0.096358 (rank : 203)	θ value	θ > 10 (rank : 648)
Query Neighborhood Hits	378	Target Neighborhood Hits	346	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

VCXC_HUMAN
NC score	0.096332 (rank : 204)	θ value	θ > 10 (rank : 716)
Query Neighborhood Hits	378	Target Neighborhood Hits	139	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

IF4G1_MOUSE
NC score	0.096318 (rank : 205)	θ value	0.000786445 (rank : 50)
Query Neighborhood Hits	378	Target Neighborhood Hits	534	Shared Neighborhood Hits	84
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

VCX1_HUMAN
NC score	0.096256 (rank : 206)	θ value	θ > 10 (rank : 713)
Query Neighborhood Hits	378	Target Neighborhood Hits	129	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

BRD4_HUMAN
NC score	0.095526 (rank : 207)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	378	Target Neighborhood Hits	851	Shared Neighborhood Hits	146
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

IF35_MOUSE
NC score	0.094894 (rank : 208)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	378	Target Neighborhood Hits	210	Shared Neighborhood Hits	79
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

CIC_MOUSE
NC score	0.094768 (rank : 209)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	378	Target Neighborhood Hits	742	Shared Neighborhood Hits	136
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

FGD1_MOUSE
NC score	0.094694 (rank : 210)	θ value	0.47712 (rank : 168)
Query Neighborhood Hits	378	Target Neighborhood Hits	387	Shared Neighborhood Hits	81
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

CHIN_MOUSE
NC score	0.094151 (rank : 211)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	378	Target Neighborhood Hits	229	Shared Neighborhood Hits	40
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CNOT3_HUMAN
NC score	0.093796 (rank : 212)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	378	Target Neighborhood Hits	425	Shared Neighborhood Hits	74
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

SF01_HUMAN
NC score	0.093727 (rank : 213)	θ value	θ > 10 (rank : 636)
Query Neighborhood Hits	378	Target Neighborhood Hits	287	Shared Neighborhood Hits	80
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SGIP1_HUMAN
NC score	0.093182 (rank : 214)	θ value	θ > 10 (rank : 645)
Query Neighborhood Hits	378	Target Neighborhood Hits	198	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

PI5PA_MOUSE
NC score	0.093095 (rank : 215)	θ value	θ > 10 (rank : 576)
Query Neighborhood Hits	378	Target Neighborhood Hits	331	Shared Neighborhood Hits	88
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

MINT_HUMAN
NC score	0.093055 (rank : 216)	θ value	8.99809 (rank : 369)
Query Neighborhood Hits	378	Target Neighborhood Hits	1291	Shared Neighborhood Hits	141
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

RPB1_HUMAN
NC score	0.092930 (rank : 217)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	378	Target Neighborhood Hits	362	Shared Neighborhood Hits	80
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RGS3_HUMAN
NC score	0.092796 (rank : 218)	θ value	0.000158464 (rank : 38)
Query Neighborhood Hits	378	Target Neighborhood Hits	1375	Shared Neighborhood Hits	144
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RPB1_MOUSE
NC score	0.092580 (rank : 219)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	378	Target Neighborhood Hits	363	Shared Neighborhood Hits	78
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

SDC3_HUMAN
NC score	0.092517 (rank : 220)	θ value	1.81305 (rank : 243)
Query Neighborhood Hits	378	Target Neighborhood Hits	103	Shared Neighborhood Hits	43
SwissProt Accessions	O75056, Q5T1Z6, Q5T1Z7, Q96CT3, Q96PR8	Gene names	SDC3, KIAA0468
Domain Architecture
Description	Syndecan-3 (SYND3).

NU214_HUMAN
NC score	0.092377 (rank : 221)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	378	Target Neighborhood Hits	657	Shared Neighborhood Hits	88
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

MAP1B_HUMAN
NC score	0.092322 (rank : 222)	θ value	0.21417 (rank : 142)
Query Neighborhood Hits	378	Target Neighborhood Hits	903	Shared Neighborhood Hits	80
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

SGIP1_MOUSE
NC score	0.092184 (rank : 223)	θ value	θ > 10 (rank : 646)
Query Neighborhood Hits	378	Target Neighborhood Hits	180	Shared Neighborhood Hits	64
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

NELFA_MOUSE
NC score	0.092011 (rank : 224)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	378	Target Neighborhood Hits	195	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

CSKI1_HUMAN
NC score	0.091953 (rank : 225)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	378	Target Neighborhood Hits	997	Shared Neighborhood Hits	149
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CK024_MOUSE
NC score	0.091658 (rank : 226)	θ value	5.27518 (rank : 307)
Query Neighborhood Hits	378	Target Neighborhood Hits	307	Shared Neighborhood Hits	48
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

IF4G1_HUMAN
NC score	0.091563 (rank : 227)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	378	Target Neighborhood Hits	347	Shared Neighborhood Hits	95
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

WASP_MOUSE
NC score	0.091481 (rank : 228)	θ value	θ > 10 (rank : 731)
Query Neighborhood Hits	378	Target Neighborhood Hits	223	Shared Neighborhood Hits	76
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

PAF49_HUMAN
NC score	0.091265 (rank : 229)	θ value	0.279714 (rank : 157)
Query Neighborhood Hits	378	Target Neighborhood Hits	169	Shared Neighborhood Hits	37
SwissProt Accessions	O15446, Q32N11, Q7Z5U2, Q9UPF6	Gene names	CD3EAP, ASE1, CAST, PAF49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (CAST).

CENB2_HUMAN
NC score	0.091089 (rank : 230)	θ value	0.00390308 (rank : 68)
Query Neighborhood Hits	378	Target Neighborhood Hits	425	Shared Neighborhood Hits	38
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

3BP1_HUMAN
NC score	0.090843 (rank : 231)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	378	Target Neighborhood Hits	376	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

SPR2B_MOUSE
NC score	0.090781 (rank : 232)	θ value	θ > 10 (rank : 657)
Query Neighborhood Hits	378	Target Neighborhood Hits	51	Shared Neighborhood Hits	12
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

PRP5_HUMAN
NC score	0.090623 (rank : 233)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	378	Target Neighborhood Hits	108	Shared Neighborhood Hits	37
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

IWS1_MOUSE
NC score	0.090467 (rank : 234)	θ value	0.00175202 (rank : 61)
Query Neighborhood Hits	378	Target Neighborhood Hits	1258	Shared Neighborhood Hits	106
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

AUTS2_HUMAN
NC score	0.090282 (rank : 235)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	378	Target Neighborhood Hits	342	Shared Neighborhood Hits	98
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

PRPC_HUMAN
NC score	0.090219 (rank : 236)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	378	Target Neighborhood Hits	165	Shared Neighborhood Hits	41
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

LCE2B_HUMAN
NC score	0.090076 (rank : 237)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	378	Target Neighborhood Hits	50	Shared Neighborhood Hits	9
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

TCOF_HUMAN
NC score	0.090062 (rank : 238)	θ value	θ > 10 (rank : 695)
Query Neighborhood Hits	378	Target Neighborhood Hits	543	Shared Neighborhood Hits	78
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TROAP_HUMAN
NC score	0.089995 (rank : 239)	θ value	θ > 10 (rank : 706)
Query Neighborhood Hits	378	Target Neighborhood Hits	258	Shared Neighborhood Hits	60
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

KPCL_HUMAN
NC score	0.089750 (rank : 240)	θ value	0.000158464 (rank : 36)
Query Neighborhood Hits	378	Target Neighborhood Hits	887	Shared Neighborhood Hits	51
SwissProt Accessions	P24723, Q16246	Gene names	PRKCH, PKCL
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

RASF1_HUMAN
NC score	0.089573 (rank : 241)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	378	Target Neighborhood Hits	62	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NS23, O14571, O60539, O60710, Q9HB04, Q9HB18, Q9NS22, Q9UND4, Q9UND5	Gene names	RASSF1, RDA32
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1.

RP1L1_HUMAN
NC score	0.089511 (rank : 242)	θ value	1.38821 (rank : 228)
Query Neighborhood Hits	378	Target Neighborhood Hits	1072	Shared Neighborhood Hits	124
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

NELFA_HUMAN
NC score	0.088969 (rank : 243)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	378	Target Neighborhood Hits	161	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H3P2, O95392	Gene names	WHSC2, NELFA
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein).

PKHA2_HUMAN
NC score	0.088786 (rank : 244)	θ value	8.99809 (rank : 373)
Query Neighborhood Hits	378	Target Neighborhood Hits	119	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

EFS_HUMAN
NC score	0.088747 (rank : 245)	θ value	0.163984 (rank : 132)
Query Neighborhood Hits	378	Target Neighborhood Hits	348	Shared Neighborhood Hits	67
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

LAD1_MOUSE
NC score	0.088451 (rank : 246)	θ value	0.47712 (rank : 173)
Query Neighborhood Hits	378	Target Neighborhood Hits	391	Shared Neighborhood Hits	62
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

KPCD_MOUSE
NC score	0.088002 (rank : 247)	θ value	0.00035302 (rank : 41)
Query Neighborhood Hits	378	Target Neighborhood Hits	888	Shared Neighborhood Hits	50
SwissProt Accessions	P28867, Q91V85, Q9Z333	Gene names	Prkcd, Pkcd
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

MINT_MOUSE
NC score	0.087961 (rank : 248)	θ value	1.38821 (rank : 223)
Query Neighborhood Hits	378	Target Neighborhood Hits	1514	Shared Neighborhood Hits	142
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

KPCL_MOUSE
NC score	0.087730 (rank : 249)	θ value	0.00020696 (rank : 40)
Query Neighborhood Hits	378	Target Neighborhood Hits	891	Shared Neighborhood Hits	51
SwissProt Accessions	P23298	Gene names	Prkch, Pkch
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

GP152_HUMAN
NC score	0.087643 (rank : 250)	θ value	0.000121331 (rank : 33)
Query Neighborhood Hits	378	Target Neighborhood Hits	636	Shared Neighborhood Hits	89
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

KPCD_HUMAN
NC score	0.087575 (rank : 251)	θ value	0.000602161 (rank : 48)
Query Neighborhood Hits	378	Target Neighborhood Hits	900	Shared Neighborhood Hits	50
SwissProt Accessions	Q05655, Q15144	Gene names	PRKCD
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

IWS1_HUMAN
NC score	0.087454 (rank : 252)	θ value	0.00665767 (rank : 74)
Query Neighborhood Hits	378	Target Neighborhood Hits	1241	Shared Neighborhood Hits	93
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LCE2C_HUMAN
NC score	0.087425 (rank : 253)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	378	Target Neighborhood Hits	53	Shared Neighborhood Hits	10
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

RTP3_MOUSE
NC score	0.087363 (rank : 254)	θ value	0.0961366 (rank : 120)
Query Neighborhood Hits	378	Target Neighborhood Hits	374	Shared Neighborhood Hits	64
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

MILK1_HUMAN
NC score	0.087326 (rank : 255)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	378	Target Neighborhood Hits	427	Shared Neighborhood Hits	94
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

SPR2F_HUMAN
NC score	0.087225 (rank : 256)	θ value	θ > 10 (rank : 662)
Query Neighborhood Hits	378	Target Neighborhood Hits	33	Shared Neighborhood Hits	8
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

MTSS1_MOUSE
NC score	0.086849 (rank : 257)	θ value	0.0431538 (rank : 102)
Query Neighborhood Hits	378	Target Neighborhood Hits	592	Shared Neighborhood Hits	70
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

MAP1B_MOUSE
NC score	0.086677 (rank : 258)	θ value	0.00869519 (rank : 77)
Query Neighborhood Hits	378	Target Neighborhood Hits	977	Shared Neighborhood Hits	84
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

TXND2_HUMAN
NC score	0.086309 (rank : 259)	θ value	5.27518 (rank : 326)
Query Neighborhood Hits	378	Target Neighborhood Hits	793	Shared Neighborhood Hits	90
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

WASP_HUMAN
NC score	0.086259 (rank : 260)	θ value	θ > 10 (rank : 730)
Query Neighborhood Hits	378	Target Neighborhood Hits	195	Shared Neighborhood Hits	69
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

NCOR2_HUMAN
NC score	0.086245 (rank : 261)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	378	Target Neighborhood Hits	870	Shared Neighborhood Hits	119
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

CENB5_HUMAN
NC score	0.086117 (rank : 262)	θ value	0.0961366 (rank : 114)
Query Neighborhood Hits	378	Target Neighborhood Hits	395	Shared Neighborhood Hits	42
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

MAP1A_HUMAN
NC score	0.085428 (rank : 263)	θ value	0.0736092 (rank : 111)
Query Neighborhood Hits	378	Target Neighborhood Hits	1626	Shared Neighborhood Hits	124
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

K1543_MOUSE
NC score	0.085394 (rank : 264)	θ value	4.03905 (rank : 293)
Query Neighborhood Hits	378	Target Neighborhood Hits	497	Shared Neighborhood Hits	77
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

CRTC1_HUMAN
NC score	0.085146 (rank : 265)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	378	Target Neighborhood Hits	319	Shared Neighborhood Hits	72
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

CSKI1_MOUSE
NC score	0.084773 (rank : 266)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	378	Target Neighborhood Hits	1031	Shared Neighborhood Hits	145
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

KPCE_MOUSE
NC score	0.084764 (rank : 267)	θ value	0.00020696 (rank : 39)
Query Neighborhood Hits	378	Target Neighborhood Hits	906	Shared Neighborhood Hits	51
SwissProt Accessions	P16054	Gene names	Prkce, Pkce, Pkcea
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

KPCT_MOUSE
NC score	0.084287 (rank : 268)	θ value	0.00035302 (rank : 44)
Query Neighborhood Hits	378	Target Neighborhood Hits	895	Shared Neighborhood Hits	51
SwissProt Accessions	Q02111	Gene names	Prkcq, Pkcq
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

ARI1A_HUMAN
NC score	0.084052 (rank : 269)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	378	Target Neighborhood Hits	787	Shared Neighborhood Hits	113
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

KPCT_HUMAN
NC score	0.083939 (rank : 270)	θ value	0.00035302 (rank : 43)
Query Neighborhood Hits	378	Target Neighborhood Hits	897	Shared Neighborhood Hits	51
SwissProt Accessions	Q04759, Q3MJF1, Q64FY5, Q9H508, Q9H549	Gene names	PRKCQ, PRKCT
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

SPR2K_MOUSE
NC score	0.083939 (rank : 271)	θ value	θ > 10 (rank : 668)
Query Neighborhood Hits	378	Target Neighborhood Hits	28	Shared Neighborhood Hits	6
SwissProt Accessions	O70562	Gene names	Sprr2k
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2K.

RIN3_MOUSE
NC score	0.083917 (rank : 272)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	378	Target Neighborhood Hits	239	Shared Neighborhood Hits	68
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

SDC3_MOUSE
NC score	0.083903 (rank : 273)	θ value	θ > 10 (rank : 632)
Query Neighborhood Hits	378	Target Neighborhood Hits	107	Shared Neighborhood Hits	41
SwissProt Accessions	Q64519, Q3UDD9, Q6ZQA4, Q7TQD4	Gene names	Sdc3, Kiaa0468
Domain Architecture
Description	Syndecan-3 precursor (SYND3).

KPCE_HUMAN
NC score	0.083883 (rank : 274)	θ value	0.00035302 (rank : 42)
Query Neighborhood Hits	378	Target Neighborhood Hits	906	Shared Neighborhood Hits	51
SwissProt Accessions	Q02156, Q53SL4, Q53SM5, Q9UE81	Gene names	PRKCE, PKCE
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

PS1C2_MOUSE
NC score	0.083639 (rank : 275)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	378	Target Neighborhood Hits	59	Shared Neighborhood Hits	23
SwissProt Accessions	Q80ZC9	Gene names	Psors1c2, Spr1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein homolog precursor (SPR1 protein).

SYP2L_HUMAN
NC score	0.083559 (rank : 276)	θ value	θ > 10 (rank : 687)
Query Neighborhood Hits	378	Target Neighborhood Hits	400	Shared Neighborhood Hits	92
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

LCE2D_HUMAN
NC score	0.083501 (rank : 277)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	378	Target Neighborhood Hits	50	Shared Neighborhood Hits	8
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

FMN1B_MOUSE
NC score	0.083479 (rank : 278)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	378	Target Neighborhood Hits	447	Shared Neighborhood Hits	101
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

MUCDL_HUMAN
NC score	0.083387 (rank : 279)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	378	Target Neighborhood Hits	777	Shared Neighborhood Hits	105
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

TAU_HUMAN
NC score	0.083121 (rank : 280)	θ value	5.27518 (rank : 325)
Query Neighborhood Hits	378	Target Neighborhood Hits	448	Shared Neighborhood Hits	82
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

SAPS1_HUMAN
NC score	0.082502 (rank : 281)	θ value	0.0148317 (rank : 85)
Query Neighborhood Hits	378	Target Neighborhood Hits	704	Shared Neighborhood Hits	99
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

MUC5B_HUMAN
NC score	0.082369 (rank : 282)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	378	Target Neighborhood Hits	1020	Shared Neighborhood Hits	116
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

PKHA4_HUMAN
NC score	0.082340 (rank : 283)	θ value	θ > 10 (rank : 578)
Query Neighborhood Hits	378	Target Neighborhood Hits	283	Shared Neighborhood Hits	77
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

CS007_MOUSE
NC score	0.081998 (rank : 284)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	378	Target Neighborhood Hits	464	Shared Neighborhood Hits	87
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

BIN1_HUMAN
NC score	0.081556 (rank : 285)	θ value	0.0148317 (rank : 83)
Query Neighborhood Hits	378	Target Neighborhood Hits	335	Shared Neighborhood Hits	39
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

FMN1A_MOUSE
NC score	0.081513 (rank : 286)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	378	Target Neighborhood Hits	423	Shared Neighborhood Hits	102
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

SEPT9_HUMAN
NC score	0.081384 (rank : 287)	θ value	1.87187e-05 (rank : 28)
Query Neighborhood Hits	378	Target Neighborhood Hits	706	Shared Neighborhood Hits	105
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

TARA_HUMAN
NC score	0.081206 (rank : 288)	θ value	θ > 10 (rank : 692)
Query Neighborhood Hits	378	Target Neighborhood Hits	1626	Shared Neighborhood Hits	156
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

LCE5A_HUMAN
NC score	0.080986 (rank : 289)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	378	Target Neighborhood Hits	43	Shared Neighborhood Hits	9
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

PKHA2_MOUSE
NC score	0.080751 (rank : 290)	θ value	θ > 10 (rank : 577)
Query Neighborhood Hits	378	Target Neighborhood Hits	116	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

SMOO_HUMAN
NC score	0.080447 (rank : 291)	θ value	θ > 10 (rank : 649)
Query Neighborhood Hits	378	Target Neighborhood Hits	391	Shared Neighborhood Hits	92
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

PTN23_MOUSE
NC score	0.080089 (rank : 292)	θ value	3.0926 (rank : 280)
Query Neighborhood Hits	378	Target Neighborhood Hits	726	Shared Neighborhood Hits	146
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

LR37B_HUMAN
NC score	0.080048 (rank : 293)	θ value	0.00134147 (rank : 56)
Query Neighborhood Hits	378	Target Neighborhood Hits	392	Shared Neighborhood Hits	48
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

PDC6I_HUMAN
NC score	0.079652 (rank : 294)	θ value	θ > 10 (rank : 564)
Query Neighborhood Hits	378	Target Neighborhood Hits	278	Shared Neighborhood Hits	88
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

RASA3_MOUSE
NC score	0.079155 (rank : 295)	θ value	0.0252991 (rank : 94)
Query Neighborhood Hits	378	Target Neighborhood Hits	144	Shared Neighborhood Hits	29
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

RIN3_HUMAN
NC score	0.079015 (rank : 296)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	378	Target Neighborhood Hits	227	Shared Neighborhood Hits	74
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

ATX2L_HUMAN
NC score	0.079008 (rank : 297)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	378	Target Neighborhood Hits	443	Shared Neighborhood Hits	87
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

MTSS1_HUMAN
NC score	0.078909 (rank : 298)	θ value	0.125558 (rank : 124)
Query Neighborhood Hits	378	Target Neighborhood Hits	504	Shared Neighborhood Hits	55
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

OGFR_MOUSE
NC score	0.078836 (rank : 299)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	378	Target Neighborhood Hits	584	Shared Neighborhood Hits	67
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

PSL1_HUMAN
NC score	0.078740 (rank : 300)	θ value	0.00134147 (rank : 59)
Query Neighborhood Hits	378	Target Neighborhood Hits	650	Shared Neighborhood Hits	68
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

ATF2_HUMAN
NC score	0.078683 (rank : 301)	θ value	0.00869519 (rank : 75)
Query Neighborhood Hits	378	Target Neighborhood Hits	402	Shared Neighborhood Hits	43
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

LIPS_HUMAN
NC score	0.078649 (rank : 302)	θ value	0.62314 (rank : 182)
Query Neighborhood Hits	378	Target Neighborhood Hits	314	Shared Neighborhood Hits	72
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

KIP1_MOUSE
NC score	0.078310 (rank : 303)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	378	Target Neighborhood Hits	109	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z0F4, Q3TN80	Gene names	Cib1, Cib, Kip, Prkdcip
Domain Architecture
Description	Calcium and integrin-binding protein 1 (Calmyrin) (DNA-PKcs- interacting protein) (Kinase-interacting protein) (KIP) (CIB).

KPCG_HUMAN
NC score	0.078275 (rank : 304)	θ value	8.99809 (rank : 363)
Query Neighborhood Hits	378	Target Neighborhood Hits	1126	Shared Neighborhood Hits	64
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

LDB3_HUMAN
NC score	0.078269 (rank : 305)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	378	Target Neighborhood Hits	497	Shared Neighborhood Hits	104
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

LCE2A_HUMAN
NC score	0.078182 (rank : 306)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	378	Target Neighborhood Hits	50	Shared Neighborhood Hits	7
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

KPCG_MOUSE
NC score	0.078110 (rank : 307)	θ value	8.99809 (rank : 364)
Query Neighborhood Hits	378	Target Neighborhood Hits	1123	Shared Neighborhood Hits	64
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

CENB1_HUMAN
NC score	0.077916 (rank : 308)	θ value	0.163984 (rank : 130)
Query Neighborhood Hits	378	Target Neighborhood Hits	383	Shared Neighborhood Hits	39
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

RTN4_HUMAN
NC score	0.077627 (rank : 309)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	378	Target Neighborhood Hits	357	Shared Neighborhood Hits	87
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

FMN2_MOUSE
NC score	0.077546 (rank : 310)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	378	Target Neighborhood Hits	349	Shared Neighborhood Hits	70
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

SPT5H_MOUSE
NC score	0.077541 (rank : 311)	θ value	1.81305 (rank : 246)
Query Neighborhood Hits	378	Target Neighborhood Hits	437	Shared Neighborhood Hits	74
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

PRAX_HUMAN
NC score	0.077132 (rank : 312)	θ value	θ > 10 (rank : 586)
Query Neighborhood Hits	378	Target Neighborhood Hits	215	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

SF01_MOUSE
NC score	0.077077 (rank : 313)	θ value	θ > 10 (rank : 637)
Query Neighborhood Hits	378	Target Neighborhood Hits	240	Shared Neighborhood Hits	61
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

ATF2_MOUSE
NC score	0.077039 (rank : 314)	θ value	0.00869519 (rank : 76)
Query Neighborhood Hits	378	Target Neighborhood Hits	397	Shared Neighborhood Hits	43
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

AMPH_MOUSE
NC score	0.076938 (rank : 315)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	378	Target Neighborhood Hits	291	Shared Neighborhood Hits	55
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

SPT5H_HUMAN
NC score	0.076938 (rank : 316)	θ value	1.81305 (rank : 245)
Query Neighborhood Hits	378	Target Neighborhood Hits	436	Shared Neighborhood Hits	72
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

TB182_HUMAN
NC score	0.076764 (rank : 317)	θ value	θ > 10 (rank : 694)
Query Neighborhood Hits	378	Target Neighborhood Hits	414	Shared Neighborhood Hits	80
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

GRIN1_MOUSE
NC score	0.076704 (rank : 318)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	378	Target Neighborhood Hits	337	Shared Neighborhood Hits	68
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

SF3A1_HUMAN
NC score	0.076343 (rank : 319)	θ value	θ > 10 (rank : 638)
Query Neighborhood Hits	378	Target Neighborhood Hits	199	Shared Neighborhood Hits	64
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

RASA3_HUMAN
NC score	0.076184 (rank : 320)	θ value	0.00869519 (rank : 78)
Query Neighborhood Hits	378	Target Neighborhood Hits	166	Shared Neighborhood Hits	31
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

WASF3_HUMAN
NC score	0.075992 (rank : 321)	θ value	θ > 10 (rank : 723)
Query Neighborhood Hits	378	Target Neighborhood Hits	204	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

K0310_HUMAN
NC score	0.075876 (rank : 322)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	378	Target Neighborhood Hits	420	Shared Neighborhood Hits	78
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

IF35_HUMAN
NC score	0.075839 (rank : 323)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	378	Target Neighborhood Hits	130	Shared Neighborhood Hits	54
SwissProt Accessions	O00303, Q8N978	Gene names	EIF3S5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

DIDO1_HUMAN
NC score	0.075391 (rank : 324)	θ value	0.163984 (rank : 131)
Query Neighborhood Hits	378	Target Neighborhood Hits	960	Shared Neighborhood Hits	108
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

ACINU_MOUSE
NC score	0.075038 (rank : 325)	θ value	6.88961 (rank : 331)
Query Neighborhood Hits	378	Target Neighborhood Hits	712	Shared Neighborhood Hits	78
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

KPCB_HUMAN
NC score	0.074219 (rank : 326)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	378	Target Neighborhood Hits	1121	Shared Neighborhood Hits	58
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCB_MOUSE
NC score	0.074101 (rank : 327)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	378	Target Neighborhood Hits	1117	Shared Neighborhood Hits	58
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

ATX2_HUMAN
NC score	0.073749 (rank : 328)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	378	Target Neighborhood Hits	375	Shared Neighborhood Hits	81
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

AFF1_MOUSE
NC score	0.073669 (rank : 329)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	378	Target Neighborhood Hits	351	Shared Neighborhood Hits	73
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

ARHGF_HUMAN
NC score	0.073619 (rank : 330)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	378	Target Neighborhood Hits	214	Shared Neighborhood Hits	75
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

TM108_MOUSE
NC score	0.073214 (rank : 331)	θ value	θ > 10 (rank : 703)
Query Neighborhood Hits	378	Target Neighborhood Hits	336	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

DIAP1_HUMAN
NC score	0.073139 (rank : 332)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	378	Target Neighborhood Hits	784	Shared Neighborhood Hits	108
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

HRX_HUMAN
NC score	0.073045 (rank : 333)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	378	Target Neighborhood Hits	825	Shared Neighborhood Hits	107
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

GNDS_HUMAN
NC score	0.073007 (rank : 334)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	378	Target Neighborhood Hits	201	Shared Neighborhood Hits	86
SwissProt Accessions	Q12967, Q9HAX7, Q9HAY1, Q9HCT1	Gene names	RALGDS, RGF
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

NOL3_MOUSE
NC score	0.072880 (rank : 335)	θ value	θ > 10 (rank : 556)
Query Neighborhood Hits	378	Target Neighborhood Hits	97	Shared Neighborhood Hits	45
SwissProt Accessions	Q9D1X0	Gene names	Nol3
Domain Architecture
Description	Nucleolar protein 3.

TM108_HUMAN
NC score	0.072772 (rank : 336)	θ value	θ > 10 (rank : 702)
Query Neighborhood Hits	378	Target Neighborhood Hits	166	Shared Neighborhood Hits	48
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

CT174_HUMAN
NC score	0.072720 (rank : 337)	θ value	1.38821 (rank : 216)
Query Neighborhood Hits	378	Target Neighborhood Hits	181	Shared Neighborhood Hits	40
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

PTN23_HUMAN
NC score	0.072617 (rank : 338)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	378	Target Neighborhood Hits	646	Shared Neighborhood Hits	122
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

DP13A_MOUSE
NC score	0.072227 (rank : 339)	θ value	0.813845 (rank : 193)
Query Neighborhood Hits	378	Target Neighborhood Hits	96	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K3H0, Q3UJP7, Q69ZJ9, Q8BWZ8, Q8VCJ8, Q9CUW4	Gene names	Appl1, Dip13a, Kiaa1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

CSKI2_HUMAN
NC score	0.072175 (rank : 340)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	378	Target Neighborhood Hits	747	Shared Neighborhood Hits	139
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

PRAX_MOUSE
NC score	0.072069 (rank : 341)	θ value	θ > 10 (rank : 587)
Query Neighborhood Hits	378	Target Neighborhood Hits	199	Shared Neighborhood Hits	43
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

KPCA_HUMAN
NC score	0.071952 (rank : 342)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	378	Target Neighborhood Hits	1070	Shared Neighborhood Hits	58
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

DP13A_HUMAN
NC score	0.071731 (rank : 343)	θ value	0.813845 (rank : 192)
Query Neighborhood Hits	378	Target Neighborhood Hits	107	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UKG1, Q9P2B9	Gene names	APPL1, APPL, DIP13A, KIAA1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

KPCA_MOUSE
NC score	0.071494 (rank : 344)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	378	Target Neighborhood Hits	1067	Shared Neighborhood Hits	58
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KIP1_HUMAN
NC score	0.071241 (rank : 345)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	378	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	Q99828, O00693, O00735, Q6IB49, Q96J54, Q99971	Gene names	CIB1, CIB, KIP, PRKDCIP
Domain Architecture
Description	Calcium and integrin-binding protein 1 (Calmyrin) (DNA-PKcs- interacting protein) (Kinase-interacting protein) (KIP) (CIB) (SNK- interacting protein 2-28) (SIP2-28).

LDB3_MOUSE
NC score	0.071116 (rank : 346)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	378	Target Neighborhood Hits	510	Shared Neighborhood Hits	108
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

CNOT3_MOUSE
NC score	0.071103 (rank : 347)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	378	Target Neighborhood Hits	504	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

ENAH_HUMAN
NC score	0.070968 (rank : 348)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	378	Target Neighborhood Hits	784	Shared Neighborhood Hits	106
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

NEUM_HUMAN
NC score	0.070694 (rank : 349)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	378	Target Neighborhood Hits	132	Shared Neighborhood Hits	36
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

RBM12_MOUSE
NC score	0.070649 (rank : 350)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	378	Target Neighborhood Hits	313	Shared Neighborhood Hits	66
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

BAZ2A_MOUSE
NC score	0.070364 (rank : 351)	θ value	0.163984 (rank : 128)
Query Neighborhood Hits	378	Target Neighborhood Hits	744	Shared Neighborhood Hits	90
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

ZYX_HUMAN
NC score	0.070345 (rank : 352)	θ value	θ > 10 (rank : 746)
Query Neighborhood Hits	378	Target Neighborhood Hits	387	Shared Neighborhood Hits	79
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

MCSP_MOUSE
NC score	0.070262 (rank : 353)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	378	Target Neighborhood Hits	108	Shared Neighborhood Hits	13
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

CASC3_MOUSE
NC score	0.070108 (rank : 354)	θ value	0.813845 (rank : 189)
Query Neighborhood Hits	378	Target Neighborhood Hits	333	Shared Neighborhood Hits	51
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

MUC13_MOUSE
NC score	0.069997 (rank : 355)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	378	Target Neighborhood Hits	447	Shared Neighborhood Hits	61
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

PRR8_HUMAN
NC score	0.069971 (rank : 356)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	378	Target Neighborhood Hits	217	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

KPCD3_MOUSE
NC score	0.069719 (rank : 357)	θ value	0.00175202 (rank : 62)
Query Neighborhood Hits	378	Target Neighborhood Hits	901	Shared Neighborhood Hits	51
SwissProt Accessions	Q8K1Y2	Gene names	Prkd3, Prkcn
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu).

ZYX_MOUSE
NC score	0.069539 (rank : 358)	θ value	θ > 10 (rank : 747)
Query Neighborhood Hits	378	Target Neighborhood Hits	347	Shared Neighborhood Hits	70
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

JPH2_MOUSE
NC score	0.069471 (rank : 359)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	378	Target Neighborhood Hits	279	Shared Neighborhood Hits	73
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

CS007_HUMAN
NC score	0.069161 (rank : 360)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	378	Target Neighborhood Hits	401	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

PRRT1_MOUSE
NC score	0.068993 (rank : 361)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	378	Target Neighborhood Hits	102	Shared Neighborhood Hits	36
SwissProt Accessions	O35449	Gene names	Prrt1, Ng5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

WASF3_MOUSE
NC score	0.068962 (rank : 362)	θ value	θ > 10 (rank : 724)
Query Neighborhood Hits	378	Target Neighborhood Hits	188	Shared Neighborhood Hits	71
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

TARA_MOUSE
NC score	0.068938 (rank : 363)	θ value	5.27518 (rank : 324)
Query Neighborhood Hits	378	Target Neighborhood Hits	1133	Shared Neighborhood Hits	120
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

LPP_HUMAN
NC score	0.068465 (rank : 364)	θ value	0.000602161 (rank : 49)
Query Neighborhood Hits	378	Target Neighborhood Hits	775	Shared Neighborhood Hits	83
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

ZAN_HUMAN
NC score	0.068420 (rank : 365)	θ value	θ > 10 (rank : 742)
Query Neighborhood Hits	378	Target Neighborhood Hits	679	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

LAD1_HUMAN
NC score	0.068419 (rank : 366)	θ value	8.99809 (rank : 365)
Query Neighborhood Hits	378	Target Neighborhood Hits	441	Shared Neighborhood Hits	51
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

PKHA4_MOUSE
NC score	0.068404 (rank : 367)	θ value	θ > 10 (rank : 579)
Query Neighborhood Hits	378	Target Neighborhood Hits	202	Shared Neighborhood Hits	52
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

DIAP1_MOUSE
NC score	0.068373 (rank : 368)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	378	Target Neighborhood Hits	839	Shared Neighborhood Hits	90
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

TCRG1_MOUSE
NC score	0.068356 (rank : 369)	θ value	θ > 10 (rank : 698)
Query Neighborhood Hits	378	Target Neighborhood Hits	947	Shared Neighborhood Hits	96
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

KPCD3_HUMAN
NC score	0.068200 (rank : 370)	θ value	0.0330416 (rank : 96)
Query Neighborhood Hits	378	Target Neighborhood Hits	895	Shared Neighborhood Hits	50
SwissProt Accessions	O94806	Gene names	PRKD3, EPK2, PRKCN
Domain Architecture
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu) (Protein kinase EPK2).

AP180_MOUSE
NC score	0.068196 (rank : 371)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	378	Target Neighborhood Hits	194	Shared Neighborhood Hits	47
SwissProt Accessions	Q61548, Q61547	Gene names	Snap91
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein) (Phosphoprotein F1- 20).

RD23B_MOUSE
NC score	0.068140 (rank : 372)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	378	Target Neighborhood Hits	189	Shared Neighborhood Hits	54
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

WNK2_HUMAN
NC score	0.068123 (rank : 373)	θ value	θ > 10 (rank : 738)
Query Neighborhood Hits	378	Target Neighborhood Hits	1407	Shared Neighborhood Hits	175
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

KPCZ_MOUSE
NC score	0.067962 (rank : 374)	θ value	0.0961366 (rank : 117)
Query Neighborhood Hits	378	Target Neighborhood Hits	882	Shared Neighborhood Hits	46
SwissProt Accessions	Q02956	Gene names	Prkcz, Pkcz
Domain Architecture
Description	Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta).

ZN598_HUMAN
NC score	0.067897 (rank : 375)	θ value	θ > 10 (rank : 745)
Query Neighborhood Hits	378	Target Neighborhood Hits	339	Shared Neighborhood Hits	57
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

3BP2_MOUSE
NC score	0.067773 (rank : 376)	θ value	1.81305 (rank : 229)
Query Neighborhood Hits	378	Target Neighborhood Hits	142	Shared Neighborhood Hits	38
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

SF3A1_MOUSE
NC score	0.067636 (rank : 377)	θ value	θ > 10 (rank : 639)
Query Neighborhood Hits	378	Target Neighborhood Hits	198	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

PDC6I_MOUSE
NC score	0.067346 (rank : 378)	θ value	θ > 10 (rank : 565)
Query Neighborhood Hits	378	Target Neighborhood Hits	275	Shared Neighborhood Hits	75
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

ENL_HUMAN
NC score	0.066999 (rank : 379)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	378	Target Neighborhood Hits	305	Shared Neighborhood Hits	54
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

AB1IP_HUMAN
NC score	0.066865 (rank : 380)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	378	Target Neighborhood Hits	213	Shared Neighborhood Hits	66
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

CT151_HUMAN
NC score	0.066855 (rank : 381)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	378	Target Neighborhood Hits	382	Shared Neighborhood Hits	55
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

BAZ2A_HUMAN
NC score	0.066713 (rank : 382)	θ value	0.21417 (rank : 140)
Query Neighborhood Hits	378	Target Neighborhood Hits	780	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

SYP2L_MOUSE
NC score	0.066630 (rank : 383)	θ value	θ > 10 (rank : 688)
Query Neighborhood Hits	378	Target Neighborhood Hits	289	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

PHLA1_HUMAN
NC score	0.066453 (rank : 384)	θ value	θ > 10 (rank : 575)
Query Neighborhood Hits	378	Target Neighborhood Hits	121	Shared Neighborhood Hits	46
SwissProt Accessions	Q8WV24, Q15184, Q2TAN2, Q9NZ17	Gene names	PHLDA1, PHRIP, TDAG51
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family A member 1 (T-cell death- associated gene 51 protein) (Apoptosis-associated nuclear protein) (Proline- and histidine-rich protein) (Proline- and glutamine-rich protein) (PQ-rich protein).

KPCD1_MOUSE
NC score	0.066390 (rank : 385)	θ value	0.0252991 (rank : 93)
Query Neighborhood Hits	378	Target Neighborhood Hits	891	Shared Neighborhood Hits	50
SwissProt Accessions	Q62101	Gene names	Prkd1, Pkcm, Pkd, Prkcm
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

KPCD2_HUMAN
NC score	0.066258 (rank : 386)	θ value	0.0431538 (rank : 101)
Query Neighborhood Hits	378	Target Neighborhood Hits	910	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BZL6, Q8TB08, Q9P0T6, Q9Y3X8	Gene names	PRKD2, PKD2
Domain Architecture
Description	Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2).

ASPP2_HUMAN
NC score	0.066248 (rank : 387)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	378	Target Neighborhood Hits	1156	Shared Neighborhood Hits	84
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

AP180_HUMAN
NC score	0.066215 (rank : 388)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	378	Target Neighborhood Hits	183	Shared Neighborhood Hits	49
SwissProt Accessions	O60641, Q5JX13, Q68DL9, Q6P9D3, Q9NTY7	Gene names	SNAP91, KIAA0656
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein).

TGON2_HUMAN
NC score	0.066063 (rank : 389)	θ value	θ > 10 (rank : 700)
Query Neighborhood Hits	378	Target Neighborhood Hits	1037	Shared Neighborhood Hits	84
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

KPCD1_HUMAN
NC score	0.065746 (rank : 390)	θ value	0.0431538 (rank : 100)
Query Neighborhood Hits	378	Target Neighborhood Hits	901	Shared Neighborhood Hits	50
SwissProt Accessions	Q15139	Gene names	PRKD1, PKD, PKD1, PRKCM
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

NFH_HUMAN
NC score	0.065477 (rank : 391)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	378	Target Neighborhood Hits	1242	Shared Neighborhood Hits	117
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CD248_HUMAN
NC score	0.065374 (rank : 392)	θ value	0.000461057 (rank : 45)
Query Neighborhood Hits	378	Target Neighborhood Hits	679	Shared Neighborhood Hits	75
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

ATX2_MOUSE
NC score	0.065191 (rank : 393)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	378	Target Neighborhood Hits	445	Shared Neighborhood Hits	81
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

ZIMP7_MOUSE
NC score	0.065180 (rank : 394)	θ value	0.0148317 (rank : 86)
Query Neighborhood Hits	378	Target Neighborhood Hits	566	Shared Neighborhood Hits	64
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

KPCZ_HUMAN
NC score	0.065038 (rank : 395)	θ value	0.279714 (rank : 153)
Query Neighborhood Hits	378	Target Neighborhood Hits	884	Shared Neighborhood Hits	46
SwissProt Accessions	Q05513, Q15207, Q5SYT5, Q969S4	Gene names	PRKCZ, PKC2
Domain Architecture
Description	Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta).

RTN4_MOUSE
NC score	0.064980 (rank : 396)	θ value	θ > 10 (rank : 626)
Query Neighborhood Hits	378	Target Neighborhood Hits	341	Shared Neighborhood Hits	76
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

PHC2_HUMAN
NC score	0.064932 (rank : 397)	θ value	0.125558 (rank : 125)
Query Neighborhood Hits	378	Target Neighborhood Hits	388	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

SPTA3_MOUSE
NC score	0.064797 (rank : 398)	θ value	θ > 10 (rank : 670)
Query Neighborhood Hits	378	Target Neighborhood Hits	74	Shared Neighborhood Hits	34
SwissProt Accessions	Q9D9T6, Q80ZS4, Q9D5L5, Q9DAF5	Gene names	Spata3, Tsarg1
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 3 (Testis spermatocyte apoptosis- related protein 1) (Testis and spermatogenesis cell-related protein 1) (mTSARG1).

JPH2_HUMAN
NC score	0.064463 (rank : 399)	θ value	0.0148317 (rank : 84)
Query Neighborhood Hits	378	Target Neighborhood Hits	639	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

CRTC1_MOUSE
NC score	0.064298 (rank : 400)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	378	Target Neighborhood Hits	230	Shared Neighborhood Hits	52
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

NPAS4_MOUSE
NC score	0.063559 (rank : 401)	θ value	0.0961366 (rank : 118)
Query Neighborhood Hits	378	Target Neighborhood Hits	245	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

NEUM_MOUSE
NC score	0.063553 (rank : 402)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	378	Target Neighborhood Hits	149	Shared Neighborhood Hits	33
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

WBS14_MOUSE
NC score	0.063144 (rank : 403)	θ value	θ > 10 (rank : 735)
Query Neighborhood Hits	378	Target Neighborhood Hits	171	Shared Neighborhood Hits	55
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

MAVS_HUMAN
NC score	0.063038 (rank : 404)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	378	Target Neighborhood Hits	271	Shared Neighborhood Hits	52
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

MKL1_MOUSE
NC score	0.063003 (rank : 405)	θ value	0.279714 (rank : 155)
Query Neighborhood Hits	378	Target Neighborhood Hits	667	Shared Neighborhood Hits	79
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

RFX1_HUMAN
NC score	0.062914 (rank : 406)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	378	Target Neighborhood Hits	256	Shared Neighborhood Hits	73
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

KPCI_HUMAN
NC score	0.062824 (rank : 407)	θ value	0.0330416 (rank : 97)
Query Neighborhood Hits	378	Target Neighborhood Hits	885	Shared Neighborhood Hits	48
SwissProt Accessions	P41743, Q8WW06	Gene names	PRKCI, DXS1179E
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota).

TAU_MOUSE
NC score	0.062741 (rank : 408)	θ value	θ > 10 (rank : 693)
Query Neighborhood Hits	378	Target Neighborhood Hits	502	Shared Neighborhood Hits	70
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

PRRT1_HUMAN
NC score	0.062709 (rank : 409)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	378	Target Neighborhood Hits	94	Shared Neighborhood Hits	34
SwissProt Accessions	Q99946, Q96DW3, Q96NQ8	Gene names	PRRT1, C6orf31, NG5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

ACINU_HUMAN
NC score	0.062593 (rank : 410)	θ value	1.81305 (rank : 230)
Query Neighborhood Hits	378	Target Neighborhood Hits	828	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

GP152_MOUSE
NC score	0.062549 (rank : 411)	θ value	0.00390308 (rank : 69)
Query Neighborhood Hits	378	Target Neighborhood Hits	607	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

EPN1_HUMAN
NC score	0.062533 (rank : 412)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	378	Target Neighborhood Hits	206	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

KPCI_MOUSE
NC score	0.062531 (rank : 413)	θ value	0.0563607 (rank : 106)
Query Neighborhood Hits	378	Target Neighborhood Hits	888	Shared Neighborhood Hits	48
SwissProt Accessions	Q62074	Gene names	Prkci, Pkcl
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota).

LARP4_MOUSE
NC score	0.062498 (rank : 414)	θ value	0.365318 (rank : 162)
Query Neighborhood Hits	378	Target Neighborhood Hits	260	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

NFRKB_HUMAN
NC score	0.062433 (rank : 415)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	378	Target Neighborhood Hits	211	Shared Neighborhood Hits	38
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

RIMB1_HUMAN
NC score	0.062378 (rank : 416)	θ value	0.00869519 (rank : 79)
Query Neighborhood Hits	378	Target Neighborhood Hits	1479	Shared Neighborhood Hits	111
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SAM14_HUMAN
NC score	0.062311 (rank : 417)	θ value	θ > 10 (rank : 629)
Query Neighborhood Hits	378	Target Neighborhood Hits	81	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IZD0, Q8N2X0	Gene names	SAMD14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

TCRG1_HUMAN
NC score	0.062159 (rank : 418)	θ value	θ > 10 (rank : 697)
Query Neighborhood Hits	378	Target Neighborhood Hits	929	Shared Neighborhood Hits	86
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

ANK2_HUMAN
NC score	0.062067 (rank : 419)	θ value	0.21417 (rank : 138)
Query Neighborhood Hits	378	Target Neighborhood Hits	1615	Shared Neighborhood Hits	138
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

TAF3_HUMAN
NC score	0.061517 (rank : 420)	θ value	θ > 10 (rank : 689)
Query Neighborhood Hits	378	Target Neighborhood Hits	568	Shared Neighborhood Hits	71
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

FGD4_MOUSE
NC score	0.061352 (rank : 421)	θ value	0.0961366 (rank : 115)
Query Neighborhood Hits	378	Target Neighborhood Hits	227	Shared Neighborhood Hits	35
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

AMOT_HUMAN
NC score	0.061262 (rank : 422)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	378	Target Neighborhood Hits	712	Shared Neighborhood Hits	84
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

PRRT3_MOUSE
NC score	0.061252 (rank : 423)	θ value	5.27518 (rank : 320)
Query Neighborhood Hits	378	Target Neighborhood Hits	162	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PE13	Gene names	Prrt3
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

3BP2_HUMAN
NC score	0.061182 (rank : 424)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	378	Target Neighborhood Hits	296	Shared Neighborhood Hits	52
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

DDEF2_HUMAN
NC score	0.061131 (rank : 425)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	378	Target Neighborhood Hits	599	Shared Neighborhood Hits	89
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

ZAN_MOUSE
NC score	0.061025 (rank : 426)	θ value	0.163984 (rank : 137)
Query Neighborhood Hits	378	Target Neighborhood Hits	808	Shared Neighborhood Hits	60
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

TENS1_HUMAN
NC score	0.060982 (rank : 427)	θ value	0.62314 (rank : 185)
Query Neighborhood Hits	378	Target Neighborhood Hits	400	Shared Neighborhood Hits	66
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

STAP1_HUMAN
NC score	0.060840 (rank : 428)	θ value	θ > 10 (rank : 680)
Query Neighborhood Hits	378	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULZ2	Gene names	STAP1, BRDG1
Domain Architecture	No domain graphic available
Description	Signal-transducing adaptor protein 1 (STAP-1) (Stem cell adaptor protein 1) (BCR downstream signaling protein 1) (Docking protein BRDG1).

3BP1_MOUSE
NC score	0.060774 (rank : 429)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	378	Target Neighborhood Hits	238	Shared Neighborhood Hits	69
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

ATX2L_MOUSE
NC score	0.060619 (rank : 430)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	378	Target Neighborhood Hits	401	Shared Neighborhood Hits	74
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

FGD4_HUMAN
NC score	0.060611 (rank : 431)	θ value	0.279714 (rank : 151)
Query Neighborhood Hits	378	Target Neighborhood Hits	219	Shared Neighborhood Hits	31
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

EP400_HUMAN
NC score	0.060495 (rank : 432)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	378	Target Neighborhood Hits	556	Shared Neighborhood Hits	122
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

NFAC1_HUMAN
NC score	0.060365 (rank : 433)	θ value	0.163984 (rank : 135)
Query Neighborhood Hits	378	Target Neighborhood Hits	312	Shared Neighborhood Hits	64
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

PRPE_HUMAN
NC score	0.060351 (rank : 434)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	378	Target Neighborhood Hits	44	Shared Neighborhood Hits	15
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

IF39_MOUSE
NC score	0.060187 (rank : 435)	θ value	5.27518 (rank : 314)
Query Neighborhood Hits	378	Target Neighborhood Hits	206	Shared Neighborhood Hits	51
SwissProt Accessions	Q8JZQ9, Q922K2	Gene names	Eif3s9
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116).

VCX2_HUMAN
NC score	0.060148 (rank : 436)	θ value	θ > 10 (rank : 714)
Query Neighborhood Hits	378	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H322, Q9P0H5	Gene names	VCX2, VCX2R, VCXB
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 2 (VCX-B protein) (Variably charged protein X-B) (Variable charge protein on X with two repeats) (VCX-2r).

PKHA6_MOUSE
NC score	0.060094 (rank : 437)	θ value	θ > 10 (rank : 581)
Query Neighborhood Hits	378	Target Neighborhood Hits	591	Shared Neighborhood Hits	74
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

MYO9B_HUMAN
NC score	0.059908 (rank : 438)	θ value	6.88961 (rank : 343)
Query Neighborhood Hits	378	Target Neighborhood Hits	641	Shared Neighborhood Hits	98
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

SMRC2_MOUSE
NC score	0.059807 (rank : 439)	θ value	θ > 10 (rank : 653)
Query Neighborhood Hits	378	Target Neighborhood Hits	487	Shared Neighborhood Hits	73
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

TFG_HUMAN
NC score	0.059670 (rank : 440)	θ value	θ > 10 (rank : 699)
Query Neighborhood Hits	378	Target Neighborhood Hits	122	Shared Neighborhood Hits	35
SwissProt Accessions	Q92734, Q15656	Gene names	TFG
Domain Architecture
Description	Protein TFG (TRK-fused gene protein).

MOT8_MOUSE
NC score	0.059500 (rank : 441)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	378	Target Neighborhood Hits	96	Shared Neighborhood Hits	56
SwissProt Accessions	O70324, Q8K3S9	Gene names	Slc16a2, Mct8, Xpct
Domain Architecture	No domain graphic available
Description	Monocarboxylate transporter 8 (MCT 8) (Solute carrier family 16 member 2) (X-linked PEST-containing transporter).

AB1IP_MOUSE
NC score	0.059375 (rank : 442)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	378	Target Neighborhood Hits	181	Shared Neighborhood Hits	61
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

CTDP1_HUMAN
NC score	0.059163 (rank : 443)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	378	Target Neighborhood Hits	416	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

FMNL_MOUSE
NC score	0.059119 (rank : 444)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	378	Target Neighborhood Hits	428	Shared Neighborhood Hits	76
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

IRS2_HUMAN
NC score	0.059075 (rank : 445)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	378	Target Neighborhood Hits	262	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

SMRC2_HUMAN
NC score	0.059014 (rank : 446)	θ value	θ > 10 (rank : 652)
Query Neighborhood Hits	378	Target Neighborhood Hits	499	Shared Neighborhood Hits	74
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

RHG25_MOUSE
NC score	0.059004 (rank : 447)	θ value	0.47712 (rank : 175)
Query Neighborhood Hits	378	Target Neighborhood Hits	492	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

TP53B_MOUSE
NC score	0.058942 (rank : 448)	θ value	θ > 10 (rank : 705)
Query Neighborhood Hits	378	Target Neighborhood Hits	644	Shared Neighborhood Hits	77
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

PDCD7_HUMAN
NC score	0.058896 (rank : 449)	θ value	θ > 10 (rank : 566)
Query Neighborhood Hits	378	Target Neighborhood Hits	255	Shared Neighborhood Hits	42
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

HGS_MOUSE
NC score	0.058704 (rank : 450)	θ value	0.365318 (rank : 161)
Query Neighborhood Hits	378	Target Neighborhood Hits	589	Shared Neighborhood Hits	65
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

PARM1_MOUSE
NC score	0.058697 (rank : 451)	θ value	θ > 10 (rank : 561)
Query Neighborhood Hits	378	Target Neighborhood Hits	140	Shared Neighborhood Hits	32
SwissProt Accessions	Q923D3, Q3TTV0, Q3UFU4	Gene names
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

CSKI2_MOUSE
NC score	0.058639 (rank : 452)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	378	Target Neighborhood Hits	812	Shared Neighborhood Hits	105
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

BPTF_HUMAN
NC score	0.058440 (rank : 453)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	378	Target Neighborhood Hits	786	Shared Neighborhood Hits	78
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BORG5_HUMAN
NC score	0.058296 (rank : 454)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	378	Target Neighborhood Hits	135	Shared Neighborhood Hits	48
SwissProt Accessions	Q00587, Q96GN1	Gene names	CDC42EP1, BORG5, CEP1, MSE55
Domain Architecture
Description	Cdc42 effector protein 1 (Binder of Rho GTPases 5) (Serum protein MSE55).

SYN2_HUMAN
NC score	0.058222 (rank : 455)	θ value	θ > 10 (rank : 684)
Query Neighborhood Hits	378	Target Neighborhood Hits	213	Shared Neighborhood Hits	66
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

CEND3_MOUSE
NC score	0.058145 (rank : 456)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	378	Target Neighborhood Hits	228	Shared Neighborhood Hits	46
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

NCOR2_MOUSE
NC score	0.058076 (rank : 457)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	378	Target Neighborhood Hits	790	Shared Neighborhood Hits	92
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

DDEF2_MOUSE
NC score	0.057980 (rank : 458)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	378	Target Neighborhood Hits	625	Shared Neighborhood Hits	82
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

VASP_HUMAN
NC score	0.057946 (rank : 459)	θ value	θ > 10 (rank : 708)
Query Neighborhood Hits	378	Target Neighborhood Hits	201	Shared Neighborhood Hits	51
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

PPRB_MOUSE
NC score	0.057914 (rank : 460)	θ value	θ > 10 (rank : 585)
Query Neighborhood Hits	378	Target Neighborhood Hits	354	Shared Neighborhood Hits	57
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

MUCDL_MOUSE
NC score	0.057879 (rank : 461)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	378	Target Neighborhood Hits	461	Shared Neighborhood Hits	73
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

GON4L_HUMAN
NC score	0.057861 (rank : 462)	θ value	0.0961366 (rank : 116)
Query Neighborhood Hits	378	Target Neighborhood Hits	555	Shared Neighborhood Hits	63
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

VAV2_HUMAN
NC score	0.057724 (rank : 463)	θ value	θ > 10 (rank : 710)
Query Neighborhood Hits	378	Target Neighborhood Hits	453	Shared Neighborhood Hits	55
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

CENA2_HUMAN
NC score	0.057720 (rank : 464)	θ value	3.0926 (rank : 266)
Query Neighborhood Hits	378	Target Neighborhood Hits	83	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

DOT1L_HUMAN
NC score	0.057533 (rank : 465)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	378	Target Neighborhood Hits	660	Shared Neighborhood Hits	76
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

VCY1_HUMAN
NC score	0.057461 (rank : 466)	θ value	θ > 10 (rank : 717)
Query Neighborhood Hits	378	Target Neighborhood Hits	38	Shared Neighborhood Hits	11
SwissProt Accessions	O14598	Gene names	VCY, BPY1
Domain Architecture	No domain graphic available
Description	Testis-specific basic protein Y 1 (Variably charged protein Y).

CEL_HUMAN
NC score	0.057351 (rank : 467)	θ value	0.0252991 (rank : 90)
Query Neighborhood Hits	378	Target Neighborhood Hits	896	Shared Neighborhood Hits	98
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

SPEG_HUMAN
NC score	0.057243 (rank : 468)	θ value	θ > 10 (rank : 654)
Query Neighborhood Hits	378	Target Neighborhood Hits	1762	Shared Neighborhood Hits	182
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ZCHC5_HUMAN
NC score	0.057141 (rank : 469)	θ value	θ > 10 (rank : 743)
Query Neighborhood Hits	378	Target Neighborhood Hits	75	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N8U3	Gene names	ZCCHC5
Domain Architecture
Description	Zinc finger CCHC domain-containing protein 5.

CEND1_HUMAN
NC score	0.056991 (rank : 470)	θ value	0.62314 (rank : 179)
Query Neighborhood Hits	378	Target Neighborhood Hits	284	Shared Neighborhood Hits	38
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

TITIN_HUMAN
NC score	0.056906 (rank : 471)	θ value	θ > 10 (rank : 701)
Query Neighborhood Hits	378	Target Neighborhood Hits	2923	Shared Neighborhood Hits	184
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

EPN1_MOUSE
NC score	0.056840 (rank : 472)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	378	Target Neighborhood Hits	240	Shared Neighborhood Hits	59
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

RU1C_MOUSE
NC score	0.056711 (rank : 473)	θ value	θ > 10 (rank : 628)
Query Neighborhood Hits	378	Target Neighborhood Hits	83	Shared Neighborhood Hits	25
SwissProt Accessions	Q62241	Gene names	Snrp1c, Snrpc
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

FHOD1_HUMAN
NC score	0.056706 (rank : 474)	θ value	0.0431538 (rank : 98)
Query Neighborhood Hits	378	Target Neighborhood Hits	184	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

CITE4_HUMAN
NC score	0.056683 (rank : 475)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	378	Target Neighborhood Hits	67	Shared Neighborhood Hits	21
SwissProt Accessions	Q96RK1	Gene names	CITED4, MRG2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

RBM12_HUMAN
NC score	0.056623 (rank : 476)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	378	Target Neighborhood Hits	298	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

RU1C_HUMAN
NC score	0.056567 (rank : 477)	θ value	θ > 10 (rank : 627)
Query Neighborhood Hits	378	Target Neighborhood Hits	81	Shared Neighborhood Hits	24
SwissProt Accessions	P09234	Gene names	SNRPC
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

MYST3_HUMAN
NC score	0.056532 (rank : 478)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	378	Target Neighborhood Hits	772	Shared Neighborhood Hits	103
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

VGF_HUMAN
NC score	0.056526 (rank : 479)	θ value	θ > 10 (rank : 718)
Query Neighborhood Hits	378	Target Neighborhood Hits	167	Shared Neighborhood Hits	39
SwissProt Accessions	O15240	Gene names	VGF
Domain Architecture	No domain graphic available
Description	Neurosecretory protein VGF precursor.

PER1_HUMAN
NC score	0.056484 (rank : 480)	θ value	θ > 10 (rank : 570)
Query Neighborhood Hits	378	Target Neighborhood Hits	215	Shared Neighborhood Hits	69
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

GRIN1_HUMAN
NC score	0.056365 (rank : 481)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	378	Target Neighborhood Hits	681	Shared Neighborhood Hits	87
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

CEND3_HUMAN
NC score	0.056216 (rank : 482)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	378	Target Neighborhood Hits	275	Shared Neighborhood Hits	62
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

NFRKB_MOUSE
NC score	0.056010 (rank : 483)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	378	Target Neighborhood Hits	393	Shared Neighborhood Hits	63
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

LCP2_HUMAN
NC score	0.055787 (rank : 484)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	378	Target Neighborhood Hits	531	Shared Neighborhood Hits	73
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

ARI1B_HUMAN
NC score	0.055676 (rank : 485)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	378	Target Neighborhood Hits	567	Shared Neighborhood Hits	87
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

CSPG5_HUMAN
NC score	0.055554 (rank : 486)	θ value	1.06291 (rank : 204)
Query Neighborhood Hits	378	Target Neighborhood Hits	199	Shared Neighborhood Hits	28
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

TAF3_MOUSE
NC score	0.055538 (rank : 487)	θ value	θ > 10 (rank : 690)
Query Neighborhood Hits	378	Target Neighborhood Hits	463	Shared Neighborhood Hits	57
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

KI67_HUMAN
NC score	0.055452 (rank : 488)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	378	Target Neighborhood Hits	581	Shared Neighborhood Hits	53
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

PHC2_MOUSE
NC score	0.055396 (rank : 489)	θ value	θ > 10 (rank : 573)
Query Neighborhood Hits	378	Target Neighborhood Hits	156	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QWH1, O88463, Q8K5D9	Gene names	Phc2, Edr2, Ph2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (mPH2) (Early development regulatory protein 2) (p36).

CEND1_MOUSE
NC score	0.055352 (rank : 490)	θ value	0.0736092 (rank : 110)
Query Neighborhood Hits	378	Target Neighborhood Hits	260	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

SPEG_MOUSE
NC score	0.055329 (rank : 491)	θ value	3.0926 (rank : 282)
Query Neighborhood Hits	378	Target Neighborhood Hits	1959	Shared Neighborhood Hits	177
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

RASA2_MOUSE
NC score	0.055315 (rank : 492)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	378	Target Neighborhood Hits	159	Shared Neighborhood Hits	32
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

SAM14_MOUSE
NC score	0.055247 (rank : 493)	θ value	θ > 10 (rank : 630)
Query Neighborhood Hits	378	Target Neighborhood Hits	91	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K070, Q5SWB7, Q8BHE2, Q8C8N5	Gene names	Samd14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

CG1_HUMAN
NC score	0.055216 (rank : 494)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	378	Target Neighborhood Hits	222	Shared Neighborhood Hits	45
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

RANB9_HUMAN
NC score	0.055153 (rank : 495)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	378	Target Neighborhood Hits	179	Shared Neighborhood Hits	56
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

CRSP2_HUMAN
NC score	0.055112 (rank : 496)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	378	Target Neighborhood Hits	380	Shared Neighborhood Hits	65
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

MRCKG_MOUSE
NC score	0.055085 (rank : 497)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	378	Target Neighborhood Hits	1466	Shared Neighborhood Hits	75
SwissProt Accessions	Q80UW5	Gene names	Cdc42bpg
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

MEGF9_MOUSE
NC score	0.054914 (rank : 498)	θ value	0.0563607 (rank : 107)
Query Neighborhood Hits	378	Target Neighborhood Hits	896	Shared Neighborhood Hits	89
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

PHC1_HUMAN
NC score	0.054758 (rank : 499)	θ value	θ > 10 (rank : 572)
Query Neighborhood Hits	378	Target Neighborhood Hits	227	Shared Neighborhood Hits	48
SwissProt Accessions	P78364, Q8WVM3, Q9BU63	Gene names	PHC1, EDR1, PH1
Domain Architecture
Description	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1).

RASA2_HUMAN
NC score	0.054677 (rank : 500)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	378	Target Neighborhood Hits	157	Shared Neighborhood Hits	29
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

PRGC2_MOUSE
NC score	0.054533 (rank : 501)	θ value	0.125558 (rank : 126)
Query Neighborhood Hits	378	Target Neighborhood Hits	225	Shared Neighborhood Hits	31
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

SPRR4_HUMAN
NC score	0.054473 (rank : 502)	θ value	θ > 10 (rank : 669)
Query Neighborhood Hits	378	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q96PI1, Q2M1Y7, Q5T522	Gene names	SPRR4
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 4.

CJ047_HUMAN
NC score	0.054237 (rank : 503)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	378	Target Neighborhood Hits	164	Shared Neighborhood Hits	41
SwissProt Accessions	Q86WR7, Q5W0J9, Q5W0K0, Q5W0K1, Q5W0K2, Q6PJC8, Q8N317	Gene names	C10orf47
Domain Architecture	No domain graphic available
Description	Protein C10orf47.

PHC3_MOUSE
NC score	0.054129 (rank : 504)	θ value	θ > 10 (rank : 574)
Query Neighborhood Hits	378	Target Neighborhood Hits	194	Shared Neighborhood Hits	49
SwissProt Accessions	Q8CHP6, Q3TLV5	Gene names	Phc3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3.

K1683_HUMAN
NC score	0.054103 (rank : 505)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	378	Target Neighborhood Hits	240	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

SRBP1_HUMAN
NC score	0.054037 (rank : 506)	θ value	θ > 10 (rank : 671)
Query Neighborhood Hits	378	Target Neighborhood Hits	225	Shared Neighborhood Hits	50
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

PKHA6_HUMAN
NC score	0.053827 (rank : 507)	θ value	θ > 10 (rank : 580)
Query Neighborhood Hits	378	Target Neighborhood Hits	556	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

BIN1_MOUSE
NC score	0.053771 (rank : 508)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	378	Target Neighborhood Hits	283	Shared Neighborhood Hits	32
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

CO002_HUMAN
NC score	0.053646 (rank : 509)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	378	Target Neighborhood Hits	387	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

DDEF1_MOUSE
NC score	0.053612 (rank : 510)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	378	Target Neighborhood Hits	592	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

VASP_MOUSE
NC score	0.053575 (rank : 511)	θ value	θ > 10 (rank : 709)
Query Neighborhood Hits	378	Target Neighborhood Hits	195	Shared Neighborhood Hits	50
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

AMELX_HUMAN
NC score	0.053569 (rank : 512)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	378	Target Neighborhood Hits	95	Shared Neighborhood Hits	33
SwissProt Accessions	Q99217, Q96NW6, Q9UCA7	Gene names	AMELX, AMG, AMGX
Domain Architecture
Description	Amelogenin, X isoform precursor.

EFS_MOUSE
NC score	0.053517 (rank : 513)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	378	Target Neighborhood Hits	389	Shared Neighborhood Hits	55
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

MEGF9_HUMAN
NC score	0.053443 (rank : 514)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	378	Target Neighborhood Hits	557	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

SC24C_HUMAN
NC score	0.053344 (rank : 515)	θ value	θ > 10 (rank : 631)
Query Neighborhood Hits	378	Target Neighborhood Hits	662	Shared Neighborhood Hits	71
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

MAST4_HUMAN
NC score	0.053279 (rank : 516)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	378	Target Neighborhood Hits	1804	Shared Neighborhood Hits	147
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

FHOD1_MOUSE
NC score	0.053187 (rank : 517)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	378	Target Neighborhood Hits	217	Shared Neighborhood Hits	45
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

CEND_HUMAN
NC score	0.053098 (rank : 518)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	378	Target Neighborhood Hits	84	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N111, Q9NYM6	Gene names	CEND1, BM88
Domain Architecture	No domain graphic available
Description	Cell cycle exit and neuronal differentiation protein 1 (BM88 antigen).

CENA1_HUMAN
NC score	0.053087 (rank : 519)	θ value	5.27518 (rank : 306)
Query Neighborhood Hits	378	Target Neighborhood Hits	87	Shared Neighborhood Hits	21
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

CO1A1_MOUSE
NC score	0.053049 (rank : 520)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	378	Target Neighborhood Hits	457	Shared Neighborhood Hits	78
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO4A5_HUMAN
NC score	0.053032 (rank : 521)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	378	Target Neighborhood Hits	383	Shared Neighborhood Hits	65
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

CI079_HUMAN
NC score	0.053027 (rank : 522)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	378	Target Neighborhood Hits	288	Shared Neighborhood Hits	52
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

PER1_MOUSE
NC score	0.052837 (rank : 523)	θ value	θ > 10 (rank : 571)
Query Neighborhood Hits	378	Target Neighborhood Hits	235	Shared Neighborhood Hits	67
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

PRCC_HUMAN
NC score	0.052811 (rank : 524)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	378	Target Neighborhood Hits	109	Shared Neighborhood Hits	30
SwissProt Accessions	Q92733, O00665, O00724	Gene names	PRCC, TPRC
Domain Architecture	No domain graphic available
Description	Proline-rich protein PRCC (Papillary renal cell carcinoma translocation-associated gene protein).

MRCKG_HUMAN
NC score	0.052796 (rank : 525)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	378	Target Neighborhood Hits	1519	Shared Neighborhood Hits	76
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

WNK4_HUMAN
NC score	0.052546 (rank : 526)	θ value	θ > 10 (rank : 739)
Query Neighborhood Hits	378	Target Neighborhood Hits	1043	Shared Neighborhood Hits	132
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

VAV2_MOUSE
NC score	0.052359 (rank : 527)	θ value	θ > 10 (rank : 711)
Query Neighborhood Hits	378	Target Neighborhood Hits	456	Shared Neighborhood Hits	55
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

COIA1_HUMAN
NC score	0.052351 (rank : 528)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	378	Target Neighborhood Hits	447	Shared Neighborhood Hits	77
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CO3A1_MOUSE
NC score	0.052350 (rank : 529)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	378	Target Neighborhood Hits	466	Shared Neighborhood Hits	78
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

BRD8_MOUSE
NC score	0.052253 (rank : 530)	θ value	6.88961 (rank : 333)
Query Neighborhood Hits	378	Target Neighborhood Hits	422	Shared Neighborhood Hits	55
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

K0460_MOUSE
NC score	0.052246 (rank : 531)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	378	Target Neighborhood Hits	374	Shared Neighborhood Hits	59
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

IF39_HUMAN
NC score	0.052235 (rank : 532)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	378	Target Neighborhood Hits	187	Shared Neighborhood Hits	38
SwissProt Accessions	P55884, Q9UMF9	Gene names	EIF3S9
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) (Prt1 homolog) (hPrt1).

NPAS4_HUMAN
NC score	0.052188 (rank : 533)	θ value	1.81305 (rank : 238)
Query Neighborhood Hits	378	Target Neighborhood Hits	214	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

MN1_HUMAN
NC score	0.052170 (rank : 534)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	378	Target Neighborhood Hits	196	Shared Neighborhood Hits	43
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

MRCKA_HUMAN
NC score	0.052148 (rank : 535)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	378	Target Neighborhood Hits	1999	Shared Neighborhood Hits	93
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

CASC3_HUMAN
NC score	0.052088 (rank : 536)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	378	Target Neighborhood Hits	204	Shared Neighborhood Hits	41
SwissProt Accessions	O15234	Gene names	CASC3, MLN51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein) (Metastatic lymph node protein 51) (Protein MLN 51) (Protein barentsz) (Btz).

K0460_HUMAN
NC score	0.052002 (rank : 537)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	378	Target Neighborhood Hits	357	Shared Neighborhood Hits	61
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

CO1A1_HUMAN
NC score	0.051990 (rank : 538)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	378	Target Neighborhood Hits	475	Shared Neighborhood Hits	81
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

PHLB1_MOUSE
NC score	0.051985 (rank : 539)	θ value	0.62314 (rank : 183)
Query Neighborhood Hits	378	Target Neighborhood Hits	678	Shared Neighborhood Hits	72
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

MISS_MOUSE
NC score	0.051967 (rank : 540)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	378	Target Neighborhood Hits	444	Shared Neighborhood Hits	57
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

SEPT9_MOUSE
NC score	0.051920 (rank : 541)	θ value	0.0113563 (rank : 82)
Query Neighborhood Hits	378	Target Neighborhood Hits	238	Shared Neighborhood Hits	33
SwissProt Accessions	Q80UG5, Q3URP2, Q80TM7, Q9QYX9	Gene names	Sept9, Kiaa0991, Sint1
Domain Architecture	No domain graphic available
Description	Septin-9 (SL3-3 integration site 1 protein).

SRCA_HUMAN
NC score	0.051772 (rank : 542)	θ value	θ > 10 (rank : 673)
Query Neighborhood Hits	378	Target Neighborhood Hits	380	Shared Neighborhood Hits	60
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

SRBP1_MOUSE
NC score	0.051762 (rank : 543)	θ value	θ > 10 (rank : 672)
Query Neighborhood Hits	378	Target Neighborhood Hits	384	Shared Neighborhood Hits	57
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

VAV_HUMAN
NC score	0.051519 (rank : 544)	θ value	θ > 10 (rank : 712)
Query Neighborhood Hits	378	Target Neighborhood Hits	452	Shared Neighborhood Hits	51
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

ELN_HUMAN
NC score	0.051389 (rank : 545)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	378	Target Neighborhood Hits	85	Shared Neighborhood Hits	11
SwissProt Accessions	P15502, O15336, O15337, Q14233, Q14234, Q14235, Q14238, Q6P0L4, Q6ZWJ6, Q75MU5, Q7Z316, Q7Z3F5, Q9UMF5	Gene names	ELN
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

AIM1_HUMAN
NC score	0.051372 (rank : 546)	θ value	2.36792 (rank : 250)
Query Neighborhood Hits	378	Target Neighborhood Hits	247	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

PXK_MOUSE
NC score	0.051354 (rank : 547)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	378	Target Neighborhood Hits	320	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BX57, Q3TD60, Q3TEL7, Q3TZZ1, Q3U197, Q3U773, Q3UCS5, Q4FBH7, Q91WB6	Gene names	Pxk
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

PARM1_HUMAN
NC score	0.051349 (rank : 548)	θ value	θ > 10 (rank : 560)
Query Neighborhood Hits	378	Target Neighborhood Hits	86	Shared Neighborhood Hits	24
SwissProt Accessions	Q6UWI2, Q96DV8, Q9Y4S1	Gene names	ames=UNQ1879/PRO4322
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

MYO15_HUMAN
NC score	0.051303 (rank : 549)	θ value	0.0113563 (rank : 80)
Query Neighborhood Hits	378	Target Neighborhood Hits	671	Shared Neighborhood Hits	92
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PO6F2_MOUSE
NC score	0.051268 (rank : 550)	θ value	θ > 10 (rank : 584)
Query Neighborhood Hits	378	Target Neighborhood Hits	639	Shared Neighborhood Hits	93
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

CSPG5_MOUSE
NC score	0.051163 (rank : 551)	θ value	0.47712 (rank : 167)
Query Neighborhood Hits	378	Target Neighborhood Hits	211	Shared Neighborhood Hits	21
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

COHA1_HUMAN
NC score	0.051150 (rank : 552)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	378	Target Neighborhood Hits	400	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

STAP1_MOUSE
NC score	0.051100 (rank : 553)	θ value	θ > 10 (rank : 681)
Query Neighborhood Hits	378	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JM90, Q3TRM1, Q6PES6	Gene names	Stap1
Domain Architecture	No domain graphic available
Description	Signal-transducing adaptor protein 1 (STAP-1) (Stem cell adaptor protein 1).

AAK1_HUMAN
NC score	0.050994 (rank : 554)	θ value	1.06291 (rank : 202)
Query Neighborhood Hits	378	Target Neighborhood Hits	1077	Shared Neighborhood Hits	105
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

RHG25_HUMAN
NC score	0.050922 (rank : 555)	θ value	1.38821 (rank : 227)
Query Neighborhood Hits	378	Target Neighborhood Hits	550	Shared Neighborhood Hits	43
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

TAB3_MOUSE
NC score	0.050840 (rank : 556)	θ value	3.0926 (rank : 283)
Query Neighborhood Hits	378	Target Neighborhood Hits	273	Shared Neighborhood Hits	50
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

CO3A1_HUMAN
NC score	0.050748 (rank : 557)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	378	Target Neighborhood Hits	452	Shared Neighborhood Hits	75
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

MYO15_MOUSE
NC score	0.050675 (rank : 558)	θ value	0.00134147 (rank : 57)
Query Neighborhood Hits	378	Target Neighborhood Hits	467	Shared Neighborhood Hits	72
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

MILK2_HUMAN
NC score	0.050623 (rank : 559)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	378	Target Neighborhood Hits	457	Shared Neighborhood Hits	73
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

MAGC1_HUMAN
NC score	0.050583 (rank : 560)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	378	Target Neighborhood Hits	431	Shared Neighborhood Hits	78
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

MBB1A_HUMAN
NC score	0.050538 (rank : 561)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	378	Target Neighborhood Hits	665	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

CNKR1_HUMAN
NC score	0.050473 (rank : 562)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	378	Target Neighborhood Hits	154	Shared Neighborhood Hits	31
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

PYGO2_HUMAN
NC score	0.050444 (rank : 563)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	378	Target Neighborhood Hits	189	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

ABI2_HUMAN
NC score	0.050156 (rank : 564)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	378	Target Neighborhood Hits	350	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

HGS_HUMAN
NC score	0.050143 (rank : 565)	θ value	1.81305 (rank : 235)
Query Neighborhood Hits	378	Target Neighborhood Hits	517	Shared Neighborhood Hits	55
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

ARID2_HUMAN
NC score	0.050043 (rank : 566)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	378	Target Neighborhood Hits	302	Shared Neighborhood Hits	45
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

ZAR1_MOUSE
NC score	0.050020 (rank : 567)	θ value	1.06291 (rank : 213)
Query Neighborhood Hits	378	Target Neighborhood Hits	254	Shared Neighborhood Hits	26
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

RP3A_MOUSE
NC score	0.049547 (rank : 568)	θ value	1.06291 (rank : 210)
Query Neighborhood Hits	378	Target Neighborhood Hits	510	Shared Neighborhood Hits	75
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

BCL7C_MOUSE
NC score	0.049424 (rank : 569)	θ value	0.62314 (rank : 178)
Query Neighborhood Hits	378	Target Neighborhood Hits	170	Shared Neighborhood Hits	30
SwissProt Accessions	O08664, Q99LS2	Gene names	Bcl7c
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member C (B-cell chronic lymphocytic leukemia/lymphoma 7C protein).

STAT2_HUMAN
NC score	0.049205 (rank : 570)	θ value	2.36792 (rank : 258)
Query Neighborhood Hits	378	Target Neighborhood Hits	99	Shared Neighborhood Hits	12
SwissProt Accessions	P52630, Q16430, Q16431	Gene names	STAT2
Domain Architecture
Description	Signal transducer and activator of transcription 2 (p113).

MYO9B_MOUSE
NC score	0.048672 (rank : 571)	θ value	6.88961 (rank : 344)
Query Neighborhood Hits	378	Target Neighborhood Hits	311	Shared Neighborhood Hits	59
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

CAMKV_HUMAN
NC score	0.048559 (rank : 572)	θ value	0.00102713 (rank : 53)
Query Neighborhood Hits	378	Target Neighborhood Hits	1084	Shared Neighborhood Hits	87
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

CENA2_MOUSE
NC score	0.048379 (rank : 573)	θ value	6.88961 (rank : 335)
Query Neighborhood Hits	378	Target Neighborhood Hits	68	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

ZN409_HUMAN
NC score	0.047834 (rank : 574)	θ value	0.0148317 (rank : 87)
Query Neighborhood Hits	378	Target Neighborhood Hits	842	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

FGD2_MOUSE
NC score	0.047649 (rank : 575)	θ value	1.06291 (rank : 205)
Query Neighborhood Hits	378	Target Neighborhood Hits	163	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

OBF1_HUMAN
NC score	0.047111 (rank : 576)	θ value	1.38821 (rank : 226)
Query Neighborhood Hits	378	Target Neighborhood Hits	203	Shared Neighborhood Hits	27
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

CD248_MOUSE
NC score	0.046607 (rank : 577)	θ value	2.36792 (rank : 252)
Query Neighborhood Hits	378	Target Neighborhood Hits	578	Shared Neighborhood Hits	60
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

ATBF1_MOUSE
NC score	0.045935 (rank : 578)	θ value	2.36792 (rank : 251)
Query Neighborhood Hits	378	Target Neighborhood Hits	1841	Shared Neighborhood Hits	157
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

AAK1_MOUSE
NC score	0.045289 (rank : 579)	θ value	1.38821 (rank : 215)
Query Neighborhood Hits	378	Target Neighborhood Hits	1051	Shared Neighborhood Hits	90
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

FGD2_HUMAN
NC score	0.044347 (rank : 580)	θ value	0.47712 (rank : 169)
Query Neighborhood Hits	378	Target Neighborhood Hits	151	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

ATX7_HUMAN
NC score	0.044317 (rank : 581)	θ value	8.99809 (rank : 357)
Query Neighborhood Hits	378	Target Neighborhood Hits	351	Shared Neighborhood Hits	57
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

TNR8_MOUSE
NC score	0.043372 (rank : 582)	θ value	0.21417 (rank : 148)
Query Neighborhood Hits	378	Target Neighborhood Hits	208	Shared Neighborhood Hits	19
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

SFR14_MOUSE
NC score	0.043041 (rank : 583)	θ value	0.21417 (rank : 147)
Query Neighborhood Hits	378	Target Neighborhood Hits	238	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CH09, Q6PG19, Q80UY8, Q8BY32, Q8CFM0	Gene names	Sfrs14
Domain Architecture	No domain graphic available
Description	Putative splicing factor, arginine/serine-rich 14 (Arginine/serine- rich-splicing factor 14).

SASH1_MOUSE
NC score	0.042936 (rank : 584)	θ value	1.06291 (rank : 211)
Query Neighborhood Hits	378	Target Neighborhood Hits	263	Shared Neighborhood Hits	42
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

AATK_HUMAN
NC score	0.042304 (rank : 585)	θ value	0.0563607 (rank : 105)
Query Neighborhood Hits	378	Target Neighborhood Hits	1243	Shared Neighborhood Hits	103
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

JIP3_HUMAN
NC score	0.042007 (rank : 586)	θ value	0.0252991 (rank : 92)
Query Neighborhood Hits	378	Target Neighborhood Hits	1039	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

CSF1_HUMAN
NC score	0.041661 (rank : 587)	θ value	4.03905 (rank : 289)
Query Neighborhood Hits	378	Target Neighborhood Hits	258	Shared Neighborhood Hits	42
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

NUMBL_HUMAN
NC score	0.041633 (rank : 588)	θ value	1.81305 (rank : 239)
Query Neighborhood Hits	378	Target Neighborhood Hits	394	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

PDLI7_HUMAN
NC score	0.041458 (rank : 589)	θ value	0.00102713 (rank : 55)
Query Neighborhood Hits	378	Target Neighborhood Hits	547	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

JADE2_MOUSE
NC score	0.041174 (rank : 590)	θ value	0.62314 (rank : 181)
Query Neighborhood Hits	378	Target Neighborhood Hits	560	Shared Neighborhood Hits	69
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

MIS_HUMAN
NC score	0.040995 (rank : 591)	θ value	0.21417 (rank : 143)
Query Neighborhood Hits	378	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	P03971, O75246	Gene names	AMH, MIF
Domain Architecture
Description	Muellerian-inhibiting factor precursor (MIS) (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance).

COFA1_MOUSE
NC score	0.040791 (rank : 592)	θ value	3.0926 (rank : 267)
Query Neighborhood Hits	378	Target Neighborhood Hits	305	Shared Neighborhood Hits	51
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

SSBP4_HUMAN
NC score	0.040339 (rank : 593)	θ value	2.36792 (rank : 257)
Query Neighborhood Hits	378	Target Neighborhood Hits	753	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

TBCD2_HUMAN
NC score	0.040274 (rank : 594)	θ value	1.81305 (rank : 247)
Query Neighborhood Hits	378	Target Neighborhood Hits	419	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

GRHL1_HUMAN
NC score	0.039963 (rank : 595)	θ value	0.47712 (rank : 170)
Query Neighborhood Hits	378	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NZI5, Q53T93, Q6NWN7, Q6NWN8, Q6NWN9, Q8NI33	Gene names	GRHL1, LBP32, MGR, TFCP2L2
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 1 homolog (Transcription factor CP2-like 2) (Transcription factor LBP-32) (NH32) (Mammalian grainyhead).

PRGC2_HUMAN
NC score	0.039563 (rank : 596)	θ value	6.88961 (rank : 347)
Query Neighborhood Hits	378	Target Neighborhood Hits	272	Shared Neighborhood Hits	36
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

FGD3_HUMAN
NC score	0.039407 (rank : 597)	θ value	5.27518 (rank : 312)
Query Neighborhood Hits	378	Target Neighborhood Hits	249	Shared Neighborhood Hits	24
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

TTBK1_HUMAN
NC score	0.039397 (rank : 598)	θ value	0.62314 (rank : 187)
Query Neighborhood Hits	378	Target Neighborhood Hits	1058	Shared Neighborhood Hits	88
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

GRHL1_MOUSE
NC score	0.039111 (rank : 599)	θ value	0.365318 (rank : 160)
Query Neighborhood Hits	378	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	Q921D9, Q8K5C1	Gene names	Grhl1, Mgr, Tcfcp2l2
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 1 homolog (Transcription factor CP2-like 2) (Transcription factor LBP-32).

CAMKV_MOUSE
NC score	0.039087 (rank : 600)	θ value	0.163984 (rank : 129)
Query Neighborhood Hits	378	Target Neighborhood Hits	848	Shared Neighborhood Hits	56
SwissProt Accessions	Q3UHL1, Q8VD20	Gene names	Camkv
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

ETV3_HUMAN
NC score	0.038818 (rank : 601)	θ value	0.279714 (rank : 150)
Query Neighborhood Hits	378	Target Neighborhood Hits	312	Shared Neighborhood Hits	45
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

TPO_MOUSE
NC score	0.038724 (rank : 602)	θ value	0.62314 (rank : 186)
Query Neighborhood Hits	378	Target Neighborhood Hits	258	Shared Neighborhood Hits	23
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

MIS_MOUSE
NC score	0.038596 (rank : 603)	θ value	0.47712 (rank : 174)
Query Neighborhood Hits	378	Target Neighborhood Hits	86	Shared Neighborhood Hits	5
SwissProt Accessions	P27106	Gene names	Amh
Domain Architecture
Description	Muellerian-inhibiting factor precursor (MIS) (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance).

OBF1_MOUSE
NC score	0.038483 (rank : 604)	θ value	2.36792 (rank : 255)
Query Neighborhood Hits	378	Target Neighborhood Hits	73	Shared Neighborhood Hits	14
SwissProt Accessions	Q64693	Gene names	Pou2af1, Obf-1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (BOB1) (OCA-B).

RFIP3_HUMAN
NC score	0.038467 (rank : 605)	θ value	0.813845 (rank : 199)
Query Neighborhood Hits	378	Target Neighborhood Hits	1055	Shared Neighborhood Hits	75
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

OBSCN_HUMAN
NC score	0.038456 (rank : 606)	θ value	1.81305 (rank : 240)
Query Neighborhood Hits	378	Target Neighborhood Hits	1931	Shared Neighborhood Hits	126
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

GLYG2_HUMAN
NC score	0.038308 (rank : 607)	θ value	0.279714 (rank : 152)
Query Neighborhood Hits	378	Target Neighborhood Hits	65	Shared Neighborhood Hits	12
SwissProt Accessions	O15488, O15485, O15486, O15487, O15489, O15490	Gene names	GYG2
Domain Architecture
Description	Glycogenin-2 (EC 2.4.1.186) (GN-2) (GN2).

HCLS1_HUMAN
NC score	0.038236 (rank : 608)	θ value	8.99809 (rank : 361)
Query Neighborhood Hits	378	Target Neighborhood Hits	358	Shared Neighborhood Hits	45
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

AATK_MOUSE
NC score	0.038169 (rank : 609)	θ value	0.0736092 (rank : 108)
Query Neighborhood Hits	378	Target Neighborhood Hits	942	Shared Neighborhood Hits	76
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

OSBP2_MOUSE
NC score	0.037706 (rank : 610)	θ value	0.00298849 (rank : 67)
Query Neighborhood Hits	378	Target Neighborhood Hits	150	Shared Neighborhood Hits	23
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

FOG1_MOUSE
NC score	0.037478 (rank : 611)	θ value	0.62314 (rank : 180)
Query Neighborhood Hits	378	Target Neighborhood Hits	1237	Shared Neighborhood Hits	129
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

GRHL2_HUMAN
NC score	0.037186 (rank : 612)	θ value	0.813845 (rank : 194)
Query Neighborhood Hits	378	Target Neighborhood Hits	22	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ISB3, Q6NT03, Q9H8B8	Gene names	GRHL2, BOM, TFCP2L3
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 2 homolog (Brother of mammalian grainyhead) (Transcription factor CP2-like 3).

GRHL2_MOUSE
NC score	0.037099 (rank : 613)	θ value	0.813845 (rank : 195)
Query Neighborhood Hits	378	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K5C0, Q80UZ5	Gene names	Grhl2, Bom, Tcfcp2l3
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 2 homolog (Brother of mammalian grainyhead) (Transcription factor CP2-like 3).

COG8_MOUSE
NC score	0.037067 (rank : 614)	θ value	0.813845 (rank : 190)
Query Neighborhood Hits	378	Target Neighborhood Hits	147	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JJA2	Gene names	Cog8
Domain Architecture
Description	Conserved oligomeric Golgi complex component 8.

ANR25_MOUSE
NC score	0.036006 (rank : 615)	θ value	1.06291 (rank : 203)
Query Neighborhood Hits	378	Target Neighborhood Hits	398	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

ITSN1_MOUSE
NC score	0.035905 (rank : 616)	θ value	0.47712 (rank : 172)
Query Neighborhood Hits	378	Target Neighborhood Hits	1669	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

LARP1_HUMAN
NC score	0.034870 (rank : 617)	θ value	6.88961 (rank : 342)
Query Neighborhood Hits	378	Target Neighborhood Hits	242	Shared Neighborhood Hits	29
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

SRC8_MOUSE
NC score	0.033734 (rank : 618)	θ value	0.0961366 (rank : 122)
Query Neighborhood Hits	378	Target Neighborhood Hits	292	Shared Neighborhood Hits	22
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

SMDF_HUMAN
NC score	0.033181 (rank : 619)	θ value	1.81305 (rank : 244)
Query Neighborhood Hits	378	Target Neighborhood Hits	117	Shared Neighborhood Hits	14
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

NEST_HUMAN
NC score	0.032544 (rank : 620)	θ value	0.813845 (rank : 198)
Query Neighborhood Hits	378	Target Neighborhood Hits	1305	Shared Neighborhood Hits	88
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

NFM_HUMAN
NC score	0.031232 (rank : 621)	θ value	0.21417 (rank : 144)
Query Neighborhood Hits	378	Target Neighborhood Hits	1328	Shared Neighborhood Hits	93
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

SVIL_MOUSE
NC score	0.031194 (rank : 622)	θ value	8.99809 (rank : 376)
Query Neighborhood Hits	378	Target Neighborhood Hits	439	Shared Neighborhood Hits	53
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

MAGD4_HUMAN
NC score	0.030979 (rank : 623)	θ value	5.27518 (rank : 317)
Query Neighborhood Hits	378	Target Neighborhood Hits	338	Shared Neighborhood Hits	57
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

ITSN1_HUMAN
NC score	0.030961 (rank : 624)	θ value	5.27518 (rank : 315)
Query Neighborhood Hits	378	Target Neighborhood Hits	1757	Shared Neighborhood Hits	97
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

MARK4_HUMAN
NC score	0.030863 (rank : 625)	θ value	0.813845 (rank : 197)
Query Neighborhood Hits	378	Target Neighborhood Hits	886	Shared Neighborhood Hits	44
SwissProt Accessions	Q96L34, Q8NG37, Q96JG7, Q96SQ2, Q9BYD8	Gene names	MARK4, KIAA1860, MARKL1
Domain Architecture
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1).

FOXO4_HUMAN
NC score	0.030732 (rank : 626)	θ value	0.0330416 (rank : 95)
Query Neighborhood Hits	378	Target Neighborhood Hits	197	Shared Neighborhood Hits	20
SwissProt Accessions	P98177, O43821, Q13720, Q3KPF1, Q8TDK9	Gene names	MLLT7, AFX, AFX1, FOXO4
Domain Architecture
Description	Fork head domain transcription factor AFX1 (Forkhead box protein O4).

ZO1_MOUSE
NC score	0.030707 (rank : 627)	θ value	0.365318 (rank : 164)
Query Neighborhood Hits	378	Target Neighborhood Hits	453	Shared Neighborhood Hits	53
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

KSR1_MOUSE
NC score	0.030403 (rank : 628)	θ value	1.38821 (rank : 222)
Query Neighborhood Hits	378	Target Neighborhood Hits	870	Shared Neighborhood Hits	43
SwissProt Accessions	Q61097, Q61648, Q78DX8	Gene names	Ksr1, Ksr
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein).

RECQ5_HUMAN
NC score	0.030237 (rank : 629)	θ value	1.81305 (rank : 242)
Query Neighborhood Hits	378	Target Neighborhood Hits	390	Shared Neighborhood Hits	43
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

LIMD1_MOUSE
NC score	0.029829 (rank : 630)	θ value	3.0926 (rank : 273)
Query Neighborhood Hits	378	Target Neighborhood Hits	291	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QXD8, Q8C8G4, Q9CW55	Gene names	Limd1
Domain Architecture
Description	LIM domain-containing protein 1.

MARK4_MOUSE
NC score	0.029785 (rank : 631)	θ value	3.0926 (rank : 275)
Query Neighborhood Hits	378	Target Neighborhood Hits	898	Shared Neighborhood Hits	44
SwissProt Accessions	Q8CIP4, Q80T81	Gene names	Mark4, Kiaa1860
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1).

TACC3_MOUSE
NC score	0.029760 (rank : 632)	θ value	0.47712 (rank : 176)
Query Neighborhood Hits	378	Target Neighborhood Hits	607	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

GMIP_MOUSE
NC score	0.029566 (rank : 633)	θ value	4.03905 (rank : 292)
Query Neighborhood Hits	378	Target Neighborhood Hits	202	Shared Neighborhood Hits	38
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

MYBPH_MOUSE
NC score	0.029116 (rank : 634)	θ value	0.0736092 (rank : 113)
Query Neighborhood Hits	378	Target Neighborhood Hits	290	Shared Neighborhood Hits	21
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

TSSK1_HUMAN
NC score	0.029050 (rank : 635)	θ value	6.88961 (rank : 350)
Query Neighborhood Hits	378	Target Neighborhood Hits	840	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BXA7	Gene names	TSSK1, SPOGA1, SPOGA4, STK22A, STK22D
Domain Architecture
Description	Testis-specific serine/threonine-protein kinase 1 (EC 2.7.11.1) (TSSK- 1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A).

CAR10_HUMAN
NC score	0.028959 (rank : 636)	θ value	0.0736092 (rank : 109)
Query Neighborhood Hits	378	Target Neighborhood Hits	569	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

PER2_MOUSE
NC score	0.028805 (rank : 637)	θ value	0.21417 (rank : 145)
Query Neighborhood Hits	378	Target Neighborhood Hits	325	Shared Neighborhood Hits	31
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

SYTL1_MOUSE
NC score	0.028723 (rank : 638)	θ value	2.36792 (rank : 259)
Query Neighborhood Hits	378	Target Neighborhood Hits	314	Shared Neighborhood Hits	38
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

SH22A_HUMAN
NC score	0.028341 (rank : 639)	θ value	3.0926 (rank : 281)
Query Neighborhood Hits	378	Target Neighborhood Hits	144	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

FOXN1_HUMAN
NC score	0.027383 (rank : 640)	θ value	0.365318 (rank : 159)
Query Neighborhood Hits	378	Target Neighborhood Hits	377	Shared Neighborhood Hits	40
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

ZCH11_HUMAN
NC score	0.026948 (rank : 641)	θ value	8.99809 (rank : 378)
Query Neighborhood Hits	378	Target Neighborhood Hits	278	Shared Neighborhood Hits	28
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

IRF7_HUMAN
NC score	0.026877 (rank : 642)	θ value	1.38821 (rank : 220)
Query Neighborhood Hits	378	Target Neighborhood Hits	73	Shared Neighborhood Hits	12
SwissProt Accessions	Q92985, O00331, O00332, O00333, O75924	Gene names	IRF7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

CABYR_MOUSE
NC score	0.026827 (rank : 643)	θ value	8.99809 (rank : 359)
Query Neighborhood Hits	378	Target Neighborhood Hits	80	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D424, Q91Y41, Q91Y42	Gene names	Cabyr, Cbp86
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86).

IPMK_HUMAN
NC score	0.026615 (rank : 644)	θ value	0.47712 (rank : 171)
Query Neighborhood Hits	378	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NFU5	Gene names	IPMK, IMPK
Domain Architecture	No domain graphic available
Description	Inositol polyphosphate multikinase (EC 2.7.1.151) (Inositol 1,3,4,6- tetrakisphosphate 5-kinase).

CAC1G_HUMAN
NC score	0.026608 (rank : 645)	θ value	3.0926 (rank : 264)
Query Neighborhood Hits	378	Target Neighborhood Hits	587	Shared Neighborhood Hits	63
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

IZUM1_MOUSE
NC score	0.026055 (rank : 646)	θ value	1.38821 (rank : 221)
Query Neighborhood Hits	378	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D9J7	Gene names	Izumo1
Domain Architecture	No domain graphic available
Description	Izumo sperm-egg fusion protein 1 precursor (Sperm-specific protein izumo).

CP003_HUMAN
NC score	0.026014 (rank : 647)	θ value	5.27518 (rank : 308)
Query Neighborhood Hits	378	Target Neighborhood Hits	56	Shared Neighborhood Hits	7
SwissProt Accessions	O95177, O95176	Gene names	C16orf3
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf3.

OXRP_HUMAN
NC score	0.025993 (rank : 648)	θ value	3.0926 (rank : 277)
Query Neighborhood Hits	378	Target Neighborhood Hits	544	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

MK15_HUMAN
NC score	0.025816 (rank : 649)	θ value	1.38821 (rank : 224)
Query Neighborhood Hits	378	Target Neighborhood Hits	1038	Shared Neighborhood Hits	65
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

ZN687_HUMAN
NC score	0.025585 (rank : 650)	θ value	0.0961366 (rank : 123)
Query Neighborhood Hits	378	Target Neighborhood Hits	1244	Shared Neighborhood Hits	90
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

CBLB_MOUSE
NC score	0.025574 (rank : 651)	θ value	5.27518 (rank : 305)
Query Neighborhood Hits	378	Target Neighborhood Hits	277	Shared Neighborhood Hits	31
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

FOXO4_MOUSE
NC score	0.025396 (rank : 652)	θ value	1.06291 (rank : 206)
Query Neighborhood Hits	378	Target Neighborhood Hits	168	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WVH3	Gene names	Mllt7, Afx, Afx1, Fkhr3, Foxo4
Domain Architecture
Description	Fork head domain transcription factor AFX1 (Afxh) (Forkhead box protein O4).

SOX13_MOUSE
NC score	0.025034 (rank : 653)	θ value	5.27518 (rank : 322)
Query Neighborhood Hits	378	Target Neighborhood Hits	495	Shared Neighborhood Hits	53
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

CAC1H_HUMAN
NC score	0.024857 (rank : 654)	θ value	3.0926 (rank : 265)
Query Neighborhood Hits	378	Target Neighborhood Hits	307	Shared Neighborhood Hits	41
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

TXLNB_MOUSE
NC score	0.024624 (rank : 655)	θ value	4.03905 (rank : 300)
Query Neighborhood Hits	378	Target Neighborhood Hits	640	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

CD008_HUMAN
NC score	0.024455 (rank : 656)	θ value	8.99809 (rank : 360)
Query Neighborhood Hits	378	Target Neighborhood Hits	330	Shared Neighborhood Hits	32
SwissProt Accessions	P78312, O43607, P78311, P78313, Q9UEG8	Gene names	C4orf8
Domain Architecture	No domain graphic available
Description	Protein C4orf8 (Protein IT14).

ITSN2_MOUSE
NC score	0.024168 (rank : 657)	θ value	5.27518 (rank : 316)
Query Neighborhood Hits	378	Target Neighborhood Hits	1371	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

PLXB1_MOUSE
NC score	0.024114 (rank : 658)	θ value	1.06291 (rank : 209)
Query Neighborhood Hits	378	Target Neighborhood Hits	259	Shared Neighborhood Hits	42
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

TXLNA_MOUSE
NC score	0.023873 (rank : 659)	θ value	0.813845 (rank : 200)
Query Neighborhood Hits	378	Target Neighborhood Hits	846	Shared Neighborhood Hits	41
SwissProt Accessions	Q6PAM1, Q6P1E5	Gene names	Txlna, Txln
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

JIP1_HUMAN
NC score	0.023827 (rank : 660)	θ value	8.99809 (rank : 362)
Query Neighborhood Hits	378	Target Neighborhood Hits	271	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

CBLB_HUMAN
NC score	0.023670 (rank : 661)	θ value	5.27518 (rank : 304)
Query Neighborhood Hits	378	Target Neighborhood Hits	261	Shared Neighborhood Hits	25
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

ELK4_HUMAN
NC score	0.023658 (rank : 662)	θ value	6.88961 (rank : 339)
Query Neighborhood Hits	378	Target Neighborhood Hits	184	Shared Neighborhood Hits	30
SwissProt Accessions	P28324, P28323	Gene names	ELK4, SAP1
Domain Architecture
Description	ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1).

PHLB2_MOUSE
NC score	0.023274 (rank : 663)	θ value	5.27518 (rank : 319)
Query Neighborhood Hits	378	Target Neighborhood Hits	1016	Shared Neighborhood Hits	54
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

AKAP8_HUMAN
NC score	0.022573 (rank : 664)	θ value	5.27518 (rank : 302)
Query Neighborhood Hits	378	Target Neighborhood Hits	166	Shared Neighborhood Hits	17
SwissProt Accessions	O43823	Gene names	AKAP8, AKAP95
Domain Architecture
Description	A-kinase anchor protein 8 (A-kinase anchor protein 95 kDa) (AKAP 95).

RTKN_HUMAN
NC score	0.022455 (rank : 665)	θ value	6.88961 (rank : 349)
Query Neighborhood Hits	378	Target Neighborhood Hits	97	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BST9, Q8WVN1, Q96PT6, Q9HB05	Gene names	RTKN
Domain Architecture	No domain graphic available
Description	Rhotekin.

CN093_HUMAN
NC score	0.022288 (rank : 666)	θ value	1.81305 (rank : 231)
Query Neighborhood Hits	378	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H972, Q86SE6, Q96CF7, Q9HA68	Gene names	C14orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf93 precursor.

EDD1_HUMAN
NC score	0.022166 (rank : 667)	θ value	1.38821 (rank : 217)
Query Neighborhood Hits	378	Target Neighborhood Hits	170	Shared Neighborhood Hits	9
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

FNBP2_HUMAN
NC score	0.022074 (rank : 668)	θ value	1.81305 (rank : 232)
Query Neighborhood Hits	378	Target Neighborhood Hits	432	Shared Neighborhood Hits	35
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

UB7I1_MOUSE
NC score	0.021712 (rank : 669)	θ value	6.88961 (rank : 351)
Query Neighborhood Hits	378	Target Neighborhood Hits	206	Shared Neighborhood Hits	31
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

TCF7_MOUSE
NC score	0.021021 (rank : 670)	θ value	0.47712 (rank : 177)
Query Neighborhood Hits	378	Target Neighborhood Hits	277	Shared Neighborhood Hits	20
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

EDD1_MOUSE
NC score	0.021004 (rank : 671)	θ value	1.38821 (rank : 218)
Query Neighborhood Hits	378	Target Neighborhood Hits	167	Shared Neighborhood Hits	9
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

MA1B1_HUMAN
NC score	0.020655 (rank : 672)	θ value	3.0926 (rank : 274)
Query Neighborhood Hits	378	Target Neighborhood Hits	125	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UKM7, Q5VSG3, Q9BRS9, Q9Y5K7	Gene names	MAN1B1
Domain Architecture
Description	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific-processing alpha-mannosidase).

MEF2B_MOUSE
NC score	0.020233 (rank : 673)	θ value	8.99809 (rank : 368)
Query Neighborhood Hits	378	Target Neighborhood Hits	218	Shared Neighborhood Hits	20
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

ZEP1_MOUSE
NC score	0.020179 (rank : 674)	θ value	4.03905 (rank : 301)
Query Neighborhood Hits	378	Target Neighborhood Hits	1063	Shared Neighborhood Hits	79
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

PHLB2_HUMAN
NC score	0.019939 (rank : 675)	θ value	8.99809 (rank : 372)
Query Neighborhood Hits	378	Target Neighborhood Hits	964	Shared Neighborhood Hits	47
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

TR13B_MOUSE
NC score	0.019900 (rank : 676)	θ value	4.03905 (rank : 298)
Query Neighborhood Hits	378	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ET35, Q9DBZ3	Gene names	Tnfrsf13b, Taci
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 13B (Transmembrane activator and CAML interactor).

PO6F1_MOUSE
NC score	0.019576 (rank : 677)	θ value	1.81305 (rank : 241)
Query Neighborhood Hits	378	Target Neighborhood Hits	581	Shared Neighborhood Hits	45
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

NFAC2_HUMAN
NC score	0.019474 (rank : 678)	θ value	8.99809 (rank : 370)
Query Neighborhood Hits	378	Target Neighborhood Hits	101	Shared Neighborhood Hits	25
SwissProt Accessions	Q13469, Q13468, Q5TFW7, Q5TFW8, Q9NPX6, Q9NQH3, Q9UJR2	Gene names	NFATC2, NFAT1, NFATP
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).

TLE6_MOUSE
NC score	0.019140 (rank : 679)	θ value	0.365318 (rank : 163)
Query Neighborhood Hits	378	Target Neighborhood Hits	178	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WVB3	Gene names	Tle6, Grg6
Domain Architecture
Description	Transducin-like enhancer protein 6 (Groucho-related protein 6).

NFIP2_HUMAN
NC score	0.018911 (rank : 680)	θ value	5.27518 (rank : 318)
Query Neighborhood Hits	378	Target Neighborhood Hits	72	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NV92, Q7Z2H3, Q7Z428, Q8TAR3, Q9ULQ5	Gene names	NDFIP2, KIAA1165, N4WBP5A
Domain Architecture	No domain graphic available
Description	NEDD4 family-interacting protein 2 (NEDD4 WW domain-binding protein 5A) (Putative MAPK-activating protein PM04/PM05/PM06/PM07) (Putative NF-kappa-B-activating protein 413).

ZEP2_HUMAN
NC score	0.018609 (rank : 681)	θ value	0.813845 (rank : 201)
Query Neighborhood Hits	378	Target Neighborhood Hits	937	Shared Neighborhood Hits	58
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

CSPG3_HUMAN
NC score	0.018100 (rank : 682)	θ value	2.36792 (rank : 253)
Query Neighborhood Hits	378	Target Neighborhood Hits	676	Shared Neighborhood Hits	55
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

IRF3_HUMAN
NC score	0.018052 (rank : 683)	θ value	2.36792 (rank : 254)
Query Neighborhood Hits	378	Target Neighborhood Hits	129	Shared Neighborhood Hits	15
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

ERBB2_HUMAN
NC score	0.017870 (rank : 684)	θ value	1.38821 (rank : 219)
Query Neighborhood Hits	378	Target Neighborhood Hits	1073	Shared Neighborhood Hits	58
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

LMO6_MOUSE
NC score	0.017518 (rank : 685)	θ value	1.81305 (rank : 237)
Query Neighborhood Hits	378	Target Neighborhood Hits	277	Shared Neighborhood Hits	21
SwissProt Accessions	Q80VL3, Q8CAY9	Gene names	Lmo6
Domain Architecture	No domain graphic available
Description	LIM domain only protein 6 (Triple LIM domain protein 6).

FRAS1_MOUSE
NC score	0.017337 (rank : 686)	θ value	1.06291 (rank : 207)
Query Neighborhood Hits	378	Target Neighborhood Hits	747	Shared Neighborhood Hits	24
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

SMBT2_MOUSE
NC score	0.017249 (rank : 687)	θ value	1.06291 (rank : 212)
Query Neighborhood Hits	378	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	Q5DTW2, Q80VG7	Gene names	Sfmbt2, Kiaa1617
Domain Architecture	No domain graphic available
Description	Scm-like with four MBT domains protein 2.

TBX2_HUMAN
NC score	0.017227 (rank : 688)	θ value	0.62314 (rank : 184)
Query Neighborhood Hits	378	Target Neighborhood Hits	195	Shared Neighborhood Hits	25
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

FA61A_MOUSE
NC score	0.016916 (rank : 689)	θ value	5.27518 (rank : 311)
Query Neighborhood Hits	378	Target Neighborhood Hits	81	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K2F8, Q9CTG8	Gene names	Fam61a
Domain Architecture	No domain graphic available
Description	Protein FAM61A.

COKA1_HUMAN
NC score	0.016816 (rank : 690)	θ value	0.813845 (rank : 191)
Query Neighborhood Hits	378	Target Neighborhood Hits	403	Shared Neighborhood Hits	29
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

FBX43_HUMAN
NC score	0.016398 (rank : 691)	θ value	3.0926 (rank : 271)
Query Neighborhood Hits	378	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q4G163	Gene names	FBXO43, EMI2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).

CAC1B_MOUSE
NC score	0.016228 (rank : 692)	θ value	0.47712 (rank : 166)
Query Neighborhood Hits	378	Target Neighborhood Hits	351	Shared Neighborhood Hits	38
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

POLS_MOUSE
NC score	0.016111 (rank : 693)	θ value	6.88961 (rank : 346)
Query Neighborhood Hits	378	Target Neighborhood Hits	91	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PB75	Gene names	Pols
Domain Architecture	No domain graphic available
Description	DNA polymerase sigma (EC 2.7.7.7).

BMPER_MOUSE
NC score	0.015984 (rank : 694)	θ value	4.03905 (rank : 287)
Query Neighborhood Hits	378	Target Neighborhood Hits	194	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

BHLH3_MOUSE
NC score	0.015458 (rank : 695)	θ value	3.0926 (rank : 263)
Query Neighborhood Hits	378	Target Neighborhood Hits	70	Shared Neighborhood Hits	7
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

ETV4_HUMAN
NC score	0.015350 (rank : 696)	θ value	4.03905 (rank : 291)
Query Neighborhood Hits	378	Target Neighborhood Hits	100	Shared Neighborhood Hits	16
SwissProt Accessions	P43268, Q96AW9	Gene names	ETV4, E1AF
Domain Architecture	No domain graphic available
Description	ETS translocation variant 4 (Adenovirus E1A enhancer-binding protein) (E1A-F).

ETV4_MOUSE
NC score	0.015335 (rank : 697)	θ value	3.0926 (rank : 270)
Query Neighborhood Hits	378	Target Neighborhood Hits	100	Shared Neighborhood Hits	14
SwissProt Accessions	P28322	Gene names	Etv4, Pea-3, Pea3
Domain Architecture
Description	ETS translocation variant 4 (Polyomavirus enhancer activator 3) (Protein PEA3).

DCC_MOUSE
NC score	0.015309 (rank : 698)	θ value	3.0926 (rank : 268)
Query Neighborhood Hits	378	Target Neighborhood Hits	896	Shared Neighborhood Hits	62
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

SIPA1_HUMAN
NC score	0.015066 (rank : 699)	θ value	4.03905 (rank : 296)
Query Neighborhood Hits	378	Target Neighborhood Hits	250	Shared Neighborhood Hits	26
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

DOK1_HUMAN
NC score	0.014704 (rank : 700)	θ value	4.03905 (rank : 290)
Query Neighborhood Hits	378	Target Neighborhood Hits	85	Shared Neighborhood Hits	11
SwissProt Accessions	Q99704, O43204, Q9UHG6	Gene names	DOK1
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)) (pp62).

DDX51_HUMAN
NC score	0.014391 (rank : 701)	θ value	5.27518 (rank : 309)
Query Neighborhood Hits	378	Target Neighborhood Hits	332	Shared Neighborhood Hits	33
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

RTBDN_MOUSE
NC score	0.013448 (rank : 702)	θ value	6.88961 (rank : 348)
Query Neighborhood Hits	378	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q8QZY4, Q6T898	Gene names	Rtbdn
Domain Architecture	No domain graphic available
Description	Retbindin precursor.

IF2M_MOUSE
NC score	0.013262 (rank : 703)	θ value	6.88961 (rank : 341)
Query Neighborhood Hits	378	Target Neighborhood Hits	183	Shared Neighborhood Hits	9
SwissProt Accessions	Q91YJ5	Gene names	Mtif2
Domain Architecture
Description	Translation initiation factor IF-2, mitochondrial precursor (IF-2Mt) (IF-2(Mt)).

FRAS1_HUMAN
NC score	0.013253 (rank : 704)	θ value	1.81305 (rank : 233)
Query Neighborhood Hits	378	Target Neighborhood Hits	759	Shared Neighborhood Hits	20
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

IF2M_HUMAN
NC score	0.013057 (rank : 705)	θ value	5.27518 (rank : 313)
Query Neighborhood Hits	378	Target Neighborhood Hits	78	Shared Neighborhood Hits	4
SwissProt Accessions	P46199	Gene names	MTIF2
Domain Architecture
Description	Translation initiation factor IF-2, mitochondrial precursor (IF-2Mt) (IF-2(Mt)).

VWF_MOUSE
NC score	0.012941 (rank : 706)	θ value	6.88961 (rank : 352)
Query Neighborhood Hits	378	Target Neighborhood Hits	381	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

AMOL1_MOUSE
NC score	0.012392 (rank : 707)	θ value	3.0926 (rank : 262)
Query Neighborhood Hits	378	Target Neighborhood Hits	445	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

TPM2_HUMAN
NC score	0.012300 (rank : 708)	θ value	1.81305 (rank : 248)
Query Neighborhood Hits	378	Target Neighborhood Hits	677	Shared Neighborhood Hits	24
SwissProt Accessions	P07951, P06468, Q13894, Q53FM4, Q5TCU4, Q5TCU7, Q9UH67	Gene names	TPM2, TMSB
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

TPM2_MOUSE
NC score	0.012117 (rank : 709)	θ value	1.81305 (rank : 249)
Query Neighborhood Hits	378	Target Neighborhood Hits	676	Shared Neighborhood Hits	24
SwissProt Accessions	P58774, P02560, P46901	Gene names	Tpm2, Tpm-2
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

FOXH1_HUMAN
NC score	0.011459 (rank : 710)	θ value	6.88961 (rank : 340)
Query Neighborhood Hits	378	Target Neighborhood Hits	258	Shared Neighborhood Hits	21
SwissProt Accessions	O75593	Gene names	FOXH1, FAST1, FAST2
Domain Architecture
Description	Forkhead box protein H1 (Forkhead activin signal transducer 1) (Fast- 1) (hFAST-1) (Forkhead activin signal transducer 2) (Fast-2).

TRIM8_HUMAN
NC score	0.011126 (rank : 711)	θ value	4.03905 (rank : 299)
Query Neighborhood Hits	378	Target Neighborhood Hits	650	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_MOUSE
NC score	0.010954 (rank : 712)	θ value	3.0926 (rank : 284)
Query Neighborhood Hits	378	Target Neighborhood Hits	674	Shared Neighborhood Hits	27
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

ERR1_HUMAN
NC score	0.010843 (rank : 713)	θ value	0.279714 (rank : 149)
Query Neighborhood Hits	378	Target Neighborhood Hits	157	Shared Neighborhood Hits	17
SwissProt Accessions	P11474, Q14514	Gene names	ESRRA, ERR1, ESRL1, NR3B1
Domain Architecture
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR- alpha) (Estrogen receptor-like 1).

SCAP_HUMAN
NC score	0.010205 (rank : 714)	θ value	5.27518 (rank : 321)
Query Neighborhood Hits	378	Target Neighborhood Hits	368	Shared Neighborhood Hits	17
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

EP15_HUMAN
NC score	0.009861 (rank : 715)	θ value	5.27518 (rank : 310)
Query Neighborhood Hits	378	Target Neighborhood Hits	1021	Shared Neighborhood Hits	37
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

MTR1L_HUMAN
NC score	0.009234 (rank : 716)	θ value	0.0736092 (rank : 112)
Query Neighborhood Hits	378	Target Neighborhood Hits	1180	Shared Neighborhood Hits	50
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

B4GT1_HUMAN
NC score	0.008942 (rank : 717)	θ value	5.27518 (rank : 303)
Query Neighborhood Hits	378	Target Neighborhood Hits	168	Shared Neighborhood Hits	13
SwissProt Accessions	P15291, Q12909, Q12910, Q12911, Q14456, Q14509, Q14523	Gene names	B4GALT1, GGTB2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

MBTP1_HUMAN
NC score	0.008803 (rank : 718)	θ value	8.99809 (rank : 367)
Query Neighborhood Hits	378	Target Neighborhood Hits	28	Shared Neighborhood Hits	6
SwissProt Accessions	Q14703, Q9UF67	Gene names	MBTPS1, KIAA0091, S1P, SKI1
Domain Architecture	No domain graphic available
Description	Membrane-bound transcription factor site 1 protease precursor (EC 3.4.21.-) (S1P endopeptidase) (Site-1 protease) (Subtilisin/kexin- isozyme 1) (SKI-1).

TNFC_MOUSE
NC score	0.008803 (rank : 719)	θ value	8.99809 (rank : 377)
Query Neighborhood Hits	378	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P41155	Gene names	Ltb, Tnfc, Tnfsf3
Domain Architecture
Description	Lymphotoxin-beta (LT-beta) (Tumor necrosis factor C) (TNF-C) (Tumor necrosis factor ligand superfamily member 3).

KLF17_HUMAN
NC score	0.008739 (rank : 720)	θ value	0.163984 (rank : 134)
Query Neighborhood Hits	378	Target Neighborhood Hits	882	Shared Neighborhood Hits	57
SwissProt Accessions	Q5JT82, Q86VQ7, Q8N805	Gene names	KLF17, ZNF393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393).

KCNQ1_MOUSE
NC score	0.008718 (rank : 721)	θ value	1.81305 (rank : 236)
Query Neighborhood Hits	378	Target Neighborhood Hits	175	Shared Neighborhood Hits	11
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

PTN22_MOUSE
NC score	0.008388 (rank : 722)	θ value	3.0926 (rank : 279)
Query Neighborhood Hits	378	Target Neighborhood Hits	179	Shared Neighborhood Hits	21
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

DAF2_MOUSE
NC score	0.008306 (rank : 723)	θ value	6.88961 (rank : 336)
Query Neighborhood Hits	378	Target Neighborhood Hits	114	Shared Neighborhood Hits	15
SwissProt Accessions	Q61476	Gene names	Cd55b, Daf2
Domain Architecture
Description	Complement decay-accelerating factor transmembrane isoform precursor (DAF-TM) (CD55 antigen).

ZN516_HUMAN
NC score	0.008172 (rank : 724)	θ value	1.06291 (rank : 214)
Query Neighborhood Hits	378	Target Neighborhood Hits	854	Shared Neighborhood Hits	50
SwissProt Accessions	Q92618	Gene names	ZNF516, KIAA0222
Domain Architecture	No domain graphic available
Description	Zinc finger protein 516.

HXB2_MOUSE
NC score	0.006335 (rank : 725)	θ value	0.813845 (rank : 196)
Query Neighborhood Hits	378	Target Neighborhood Hits	350	Shared Neighborhood Hits	16
SwissProt Accessions	P0C1T1	Gene names	Hoxb2, Hox-2.8
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-B2 (Hox-2.8).

NID2_HUMAN
NC score	0.006270 (rank : 726)	θ value	6.88961 (rank : 345)
Query Neighborhood Hits	378	Target Neighborhood Hits	456	Shared Neighborhood Hits	30
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

PGM2L_MOUSE
NC score	0.005771 (rank : 727)	θ value	8.99809 (rank : 371)
Query Neighborhood Hits	378	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CAA7	Gene names	Pgm2l1
Domain Architecture	No domain graphic available
Description	Phosphoglucomutase-2-like 1 (EC 5.4.2.2).

ACE_HUMAN
NC score	0.005746 (rank : 728)	θ value	6.88961 (rank : 330)
Query Neighborhood Hits	378	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	P12821, Q53YX9, Q59GY8	Gene names	ACE, DCP, DCP1
Domain Architecture
Description	Angiotensin-converting enzyme, somatic isoform precursor (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD143 antigen) [Contains: Angiotensin-converting enzyme, somatic isoform, soluble form].

ZN358_HUMAN
NC score	0.005580 (rank : 729)	θ value	5.27518 (rank : 329)
Query Neighborhood Hits	378	Target Neighborhood Hits	840	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NW07, Q9BTM7	Gene names	ZNF358
Domain Architecture
Description	Zinc finger protein 358.

AAKG3_MOUSE
NC score	0.005244 (rank : 730)	θ value	8.99809 (rank : 356)
Query Neighborhood Hits	378	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGM7, Q80WK8, Q8CJ41	Gene names	Prkag3
Domain Architecture	No domain graphic available
Description	5'-AMP-activated protein kinase subunit gamma-3 (AMPK gamma-3 chain) (AMPK gamma3).

EGFL9_MOUSE
NC score	0.005127 (rank : 731)	θ value	3.0926 (rank : 269)
Query Neighborhood Hits	378	Target Neighborhood Hits	379	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

KIF17_HUMAN
NC score	0.005037 (rank : 732)	θ value	3.0926 (rank : 272)
Query Neighborhood Hits	378	Target Neighborhood Hits	365	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P2E2, O95077, Q53YS6, Q5VWA9, Q6GSA8, Q8N411	Gene names	KIF17, KIAA1405, KIF3X
Domain Architecture
Description	Kinesin-like protein KIF17 (KIF3-related motor protein).

DNER_HUMAN
NC score	0.004475 (rank : 733)	θ value	6.88961 (rank : 337)
Query Neighborhood Hits	378	Target Neighborhood Hits	460	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

ZN217_HUMAN
NC score	0.004473 (rank : 734)	θ value	5.27518 (rank : 328)
Query Neighborhood Hits	378	Target Neighborhood Hits	905	Shared Neighborhood Hits	49
SwissProt Accessions	O75362	Gene names	ZNF217, ZABC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 217.

GLI1_HUMAN
NC score	0.004098 (rank : 735)	θ value	1.81305 (rank : 234)
Query Neighborhood Hits	378	Target Neighborhood Hits	828	Shared Neighborhood Hits	45
SwissProt Accessions	P08151, Q8TDN9	Gene names	GLI1, GLI
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI).

STAB2_MOUSE
NC score	0.003773 (rank : 736)	θ value	8.99809 (rank : 375)
Query Neighborhood Hits	378	Target Neighborhood Hits	528	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

SIG10_HUMAN
NC score	0.003694 (rank : 737)	θ value	8.99809 (rank : 374)
Query Neighborhood Hits	378	Target Neighborhood Hits	363	Shared Neighborhood Hits	22
SwissProt Accessions	Q96LC7, Q6UXI8, Q96G54, Q96LC8	Gene names	SIGLEC10, SLG2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 10 precursor (Siglec-10) (Siglec- like protein 2).

OVOL1_HUMAN
NC score	0.002932 (rank : 738)	θ value	1.06291 (rank : 208)
Query Neighborhood Hits	378	Target Neighborhood Hits	729	Shared Neighborhood Hits	24
SwissProt Accessions	O14753, Q6PCB1	Gene names	OVOL1
Domain Architecture	No domain graphic available
Description	Putative transcription factor Ovo-like 1 (hOvo1).

PRP17_HUMAN
NC score	0.002378 (rank : 739)	θ value	3.0926 (rank : 278)
Query Neighborhood Hits	378	Target Neighborhood Hits	297	Shared Neighborhood Hits	4
SwissProt Accessions	O60508, O75471, Q9UPG1	Gene names	CDC40, PRP17
Domain Architecture
Description	Pre-mRNA-splicing factor PRP17 (hPRP17) (Cell division cycle 40 homolog) (EH-binding protein 3) (Ehb3).

OVOL1_MOUSE
NC score	0.002164 (rank : 740)	θ value	4.03905 (rank : 294)
Query Neighborhood Hits	378	Target Neighborhood Hits	716	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WTJ2, Q545S2	Gene names	Ovol1
Domain Architecture	No domain graphic available
Description	Putative transcription factor Ovo-like 1 (mOvo1) (mOvo1a).

EGR4_HUMAN
NC score	0.002117 (rank : 741)	θ value	6.88961 (rank : 338)
Query Neighborhood Hits	378	Target Neighborhood Hits	939	Shared Neighborhood Hits	46
SwissProt Accessions	Q05215	Gene names	EGR4
Domain Architecture
Description	Early growth response protein 4 (EGR-4) (AT133).

ZN688_HUMAN
NC score	0.000832 (rank : 742)	θ value	2.36792 (rank : 261)
Query Neighborhood Hits	378	Target Neighborhood Hits	873	Shared Neighborhood Hits	52
SwissProt Accessions	Q8WV14, O75701, Q8IW91, Q96MN0	Gene names	ZNF688
Domain Architecture	No domain graphic available
Description	Zinc finger protein 688.

ZN206_HUMAN
NC score	0.000257 (rank : 743)	θ value	6.88961 (rank : 353)
Query Neighborhood Hits	378	Target Neighborhood Hits	853	Shared Neighborhood Hits	53
SwissProt Accessions	Q96SZ4	Gene names	ZNF206, ZSCAN10
Domain Architecture	No domain graphic available
Description	Zinc finger protein 206 (Zinc finger and SCAN domain-containing protein 10).

ZN710_HUMAN
NC score	-0.000634 (rank : 744)	θ value	6.88961 (rank : 354)
Query Neighborhood Hits	378	Target Neighborhood Hits	796	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N1W2, Q6ZMK9, Q8NDU0	Gene names	ZNF710
Domain Architecture	No domain graphic available
Description	Zinc finger protein 710.

ZN286_HUMAN
NC score	-0.000765 (rank : 745)	θ value	3.0926 (rank : 285)
Query Neighborhood Hits	378	Target Neighborhood Hits	775	Shared Neighborhood Hits	29
SwissProt Accessions	Q9HBT8, Q96JF3	Gene names	ZNF286, KIAA1874
Domain Architecture
Description	Zinc finger protein 286.

ZNF8_HUMAN
NC score	-0.001954 (rank : 746)	θ value	6.88961 (rank : 355)
Query Neighborhood Hits	378	Target Neighborhood Hits	748	Shared Neighborhood Hits	27
SwissProt Accessions	P17098, Q6PI99	Gene names	ZNF8
Domain Architecture	No domain graphic available
Description	Zinc finger protein 8 (Zinc finger protein HF.18).

ADRB2_MOUSE
NC score	-0.007616 (rank : 747)	θ value	6.88961 (rank : 332)
Query Neighborhood Hits	378	Target Neighborhood Hits	923	Shared Neighborhood Hits	3
SwissProt Accessions	P18762	Gene names	Adrb2, Adrb2r
Domain Architecture
Description	Beta-2 adrenergic receptor (Beta-2 adrenoceptor) (Beta-2 adrenoreceptor).