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Network neighborhood for query Sequence : AMPH_HUMAN

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AMPH_HUMAN
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

AMPH_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	455	Target Neighborhood Hits	455	Shared Neighborhood Hits	455
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

AMPH_MOUSE
θ value	0 (rank : 2)	NC score	0.926014 (rank : 2)
Query Neighborhood Hits	455	Target Neighborhood Hits	291	Shared Neighborhood Hits	224
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

BIN1_HUMAN
θ value	1.06234e-117 (rank : 3)	NC score	0.822528 (rank : 4)
Query Neighborhood Hits	455	Target Neighborhood Hits	335	Shared Neighborhood Hits	119
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

BIN1_MOUSE
θ value	3.09092e-117 (rank : 4)	NC score	0.823478 (rank : 3)
Query Neighborhood Hits	455	Target Neighborhood Hits	283	Shared Neighborhood Hits	105
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

DNMBP_HUMAN
θ value	1.99992e-07 (rank : 5)	NC score	0.260551 (rank : 8)
Query Neighborhood Hits	455	Target Neighborhood Hits	413	Shared Neighborhood Hits	112
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

BIN3_MOUSE
θ value	4.45536e-07 (rank : 6)	NC score	0.340014 (rank : 5)
Query Neighborhood Hits	455	Target Neighborhood Hits	165	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JI08	Gene names	Bin3
Domain Architecture	No domain graphic available
Description	Bridging integrator 3.

BIN3_HUMAN
θ value	2.88788e-06 (rank : 7)	NC score	0.339596 (rank : 6)
Query Neighborhood Hits	455	Target Neighborhood Hits	95	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NQY0, Q9BVG2, Q9NVY9	Gene names	BIN3
Domain Architecture
Description	Bridging integrator 3.

CN155_HUMAN
θ value	8.40245e-06 (rank : 8)	NC score	0.210200 (rank : 24)
Query Neighborhood Hits	455	Target Neighborhood Hits	385	Shared Neighborhood Hits	89
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

DNMBP_MOUSE
θ value	1.43324e-05 (rank : 9)	NC score	0.248888 (rank : 13)
Query Neighborhood Hits	455	Target Neighborhood Hits	435	Shared Neighborhood Hits	117
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

ZAN_MOUSE
θ value	1.43324e-05 (rank : 10)	NC score	0.069517 (rank : 451)
Query Neighborhood Hits	455	Target Neighborhood Hits	808	Shared Neighborhood Hits	43
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

NACAM_MOUSE
θ value	3.19293e-05 (rank : 11)	NC score	0.210313 (rank : 23)
Query Neighborhood Hits	455	Target Neighborhood Hits	1866	Shared Neighborhood Hits	221
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

M3K9_HUMAN
θ value	5.44631e-05 (rank : 12)	NC score	0.079376 (rank : 305)
Query Neighborhood Hits	455	Target Neighborhood Hits	1123	Shared Neighborhood Hits	119
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

HCK_MOUSE
θ value	7.1131e-05 (rank : 13)	NC score	0.056147 (rank : 731)
Query Neighborhood Hits	455	Target Neighborhood Hits	1029	Shared Neighborhood Hits	93
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

ABI2_HUMAN
θ value	0.000158464 (rank : 14)	NC score	0.266749 (rank : 7)
Query Neighborhood Hits	455	Target Neighborhood Hits	350	Shared Neighborhood Hits	111
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ABI2_MOUSE
θ value	0.000158464 (rank : 15)	NC score	0.257524 (rank : 9)
Query Neighborhood Hits	455	Target Neighborhood Hits	266	Shared Neighborhood Hits	91
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

LARP4_HUMAN
θ value	0.000158464 (rank : 16)	NC score	0.093211 (rank : 203)
Query Neighborhood Hits	455	Target Neighborhood Hits	69	Shared Neighborhood Hits	15
SwissProt Accessions	Q71RC2, Q5CZ97, Q96NF9	Gene names	LARP4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

SON_HUMAN
θ value	0.00035302 (rank : 17)	NC score	0.162902 (rank : 53)
Query Neighborhood Hits	455	Target Neighborhood Hits	1568	Shared Neighborhood Hits	186
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

RP1L1_HUMAN
θ value	0.000786445 (rank : 18)	NC score	0.130393 (rank : 94)
Query Neighborhood Hits	455	Target Neighborhood Hits	1072	Shared Neighborhood Hits	140
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

STAM1_MOUSE
θ value	0.000786445 (rank : 19)	NC score	0.229642 (rank : 17)
Query Neighborhood Hits	455	Target Neighborhood Hits	273	Shared Neighborhood Hits	88
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

MARCS_MOUSE
θ value	0.00102713 (rank : 20)	NC score	0.169099 (rank : 51)
Query Neighborhood Hits	455	Target Neighborhood Hits	227	Shared Neighborhood Hits	49
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MRCKB_MOUSE
θ value	0.00175202 (rank : 21)	NC score	0.066682 (rank : 505)
Query Neighborhood Hits	455	Target Neighborhood Hits	2180	Shared Neighborhood Hits	180
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

SNX6_HUMAN
θ value	0.00175202 (rank : 22)	NC score	0.134735 (rank : 82)
Query Neighborhood Hits	455	Target Neighborhood Hits	52	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UNH7, Q9Y449	Gene names	SNX6
Domain Architecture
Description	Sorting nexin-6 (TRAF4-associated factor 2).

SNX6_MOUSE
θ value	0.00175202 (rank : 23)	NC score	0.135181 (rank : 81)
Query Neighborhood Hits	455	Target Neighborhood Hits	52	Shared Neighborhood Hits	17
SwissProt Accessions	Q6P8X1	Gene names	Snx6
Domain Architecture	No domain graphic available
Description	Sorting nexin-6.

SRCA_HUMAN
θ value	0.00175202 (rank : 24)	NC score	0.097634 (rank : 178)
Query Neighborhood Hits	455	Target Neighborhood Hits	380	Shared Neighborhood Hits	63
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

DGKK_HUMAN
θ value	0.00228821 (rank : 25)	NC score	0.105459 (rank : 150)
Query Neighborhood Hits	455	Target Neighborhood Hits	378	Shared Neighborhood Hits	66
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

M3K10_HUMAN
θ value	0.00228821 (rank : 26)	NC score	0.068397 (rank : 471)
Query Neighborhood Hits	455	Target Neighborhood Hits	1071	Shared Neighborhood Hits	106
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

NFH_MOUSE
θ value	0.00228821 (rank : 27)	NC score	0.147091 (rank : 66)
Query Neighborhood Hits	455	Target Neighborhood Hits	2247	Shared Neighborhood Hits	276
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

LASP1_HUMAN
θ value	0.00298849 (rank : 28)	NC score	0.212922 (rank : 21)
Query Neighborhood Hits	455	Target Neighborhood Hits	293	Shared Neighborhood Hits	84
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

MOT8_MOUSE
θ value	0.00298849 (rank : 29)	NC score	0.081523 (rank : 273)
Query Neighborhood Hits	455	Target Neighborhood Hits	96	Shared Neighborhood Hits	20
SwissProt Accessions	O70324, Q8K3S9	Gene names	Slc16a2, Mct8, Xpct
Domain Architecture	No domain graphic available
Description	Monocarboxylate transporter 8 (MCT 8) (Solute carrier family 16 member 2) (X-linked PEST-containing transporter).

ARHGG_HUMAN
θ value	0.00390308 (rank : 30)	NC score	0.131125 (rank : 89)
Query Neighborhood Hits	455	Target Neighborhood Hits	129	Shared Neighborhood Hits	39
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

M3KL4_HUMAN
θ value	0.00390308 (rank : 31)	NC score	0.079399 (rank : 304)
Query Neighborhood Hits	455	Target Neighborhood Hits	1087	Shared Neighborhood Hits	112
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

STAM2_HUMAN
θ value	0.00390308 (rank : 32)	NC score	0.214437 (rank : 19)
Query Neighborhood Hits	455	Target Neighborhood Hits	288	Shared Neighborhood Hits	89
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

DDEF2_MOUSE
θ value	0.00509761 (rank : 33)	NC score	0.137939 (rank : 74)
Query Neighborhood Hits	455	Target Neighborhood Hits	625	Shared Neighborhood Hits	113
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

SH3K1_HUMAN
θ value	0.00509761 (rank : 34)	NC score	0.255972 (rank : 10)
Query Neighborhood Hits	455	Target Neighborhood Hits	341	Shared Neighborhood Hits	105
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SH3K1_MOUSE
θ value	0.00509761 (rank : 35)	NC score	0.252257 (rank : 12)
Query Neighborhood Hits	455	Target Neighborhood Hits	332	Shared Neighborhood Hits	106
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

TAU_HUMAN
θ value	0.00509761 (rank : 36)	NC score	0.119958 (rank : 117)
Query Neighborhood Hits	455	Target Neighborhood Hits	448	Shared Neighborhood Hits	85
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

OGFR_HUMAN
θ value	0.00665767 (rank : 37)	NC score	0.160431 (rank : 55)
Query Neighborhood Hits	455	Target Neighborhood Hits	1582	Shared Neighborhood Hits	199
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

STAM1_HUMAN
θ value	0.00665767 (rank : 38)	NC score	0.219818 (rank : 18)
Query Neighborhood Hits	455	Target Neighborhood Hits	271	Shared Neighborhood Hits	87
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

ABI3_MOUSE
θ value	0.00869519 (rank : 39)	NC score	0.203813 (rank : 26)
Query Neighborhood Hits	455	Target Neighborhood Hits	227	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

CCNK_MOUSE
θ value	0.00869519 (rank : 40)	NC score	0.091741 (rank : 209)
Query Neighborhood Hits	455	Target Neighborhood Hits	350	Shared Neighborhood Hits	58
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

ITSN1_MOUSE
θ value	0.00869519 (rank : 41)	NC score	0.189294 (rank : 35)
Query Neighborhood Hits	455	Target Neighborhood Hits	1669	Shared Neighborhood Hits	236
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

SRCA_MOUSE
θ value	0.00869519 (rank : 42)	NC score	0.095500 (rank : 189)
Query Neighborhood Hits	455	Target Neighborhood Hits	212	Shared Neighborhood Hits	42
SwissProt Accessions	Q7TQ48, Q8BS43	Gene names	Srl, Sar
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

DDEF2_HUMAN
θ value	0.0113563 (rank : 43)	NC score	0.134634 (rank : 83)
Query Neighborhood Hits	455	Target Neighborhood Hits	599	Shared Neighborhood Hits	119
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

LMBL3_MOUSE
θ value	0.0113563 (rank : 44)	NC score	0.053714 (rank : 783)
Query Neighborhood Hits	455	Target Neighborhood Hits	212	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BLB7, Q641L7, Q6ZPI2, Q8C0G4	Gene names	L3mbtl3
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein).

M3K11_HUMAN
θ value	0.0113563 (rank : 45)	NC score	0.073849 (rank : 386)
Query Neighborhood Hits	455	Target Neighborhood Hits	1136	Shared Neighborhood Hits	129
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

STS2_HUMAN
θ value	0.0113563 (rank : 46)	NC score	0.198486 (rank : 30)
Query Neighborhood Hits	455	Target Neighborhood Hits	108	Shared Neighborhood Hits	57
SwissProt Accessions	P57075, Q6HA34, Q6HA35, Q6ISI6, Q6ISK3, Q6ISS9	Gene names	UBASH3A, STS2
Domain Architecture
Description	Suppressor of T-cell receptor signaling 2 (STS-2) (Cbl-interacting protein 4) (CLIP4) (T-cell ubiquitin ligand) (TULA).

ABI1_MOUSE
θ value	0.0148317 (rank : 47)	NC score	0.253893 (rank : 11)
Query Neighborhood Hits	455	Target Neighborhood Hits	246	Shared Neighborhood Hits	93
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

HCK_HUMAN
θ value	0.0148317 (rank : 48)	NC score	0.049583 (rank : 859)
Query Neighborhood Hits	455	Target Neighborhood Hits	1035	Shared Neighborhood Hits	93
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

ITSN1_HUMAN
θ value	0.0148317 (rank : 49)	NC score	0.188531 (rank : 36)
Query Neighborhood Hits	455	Target Neighborhood Hits	1757	Shared Neighborhood Hits	244
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ROCK1_HUMAN
θ value	0.0148317 (rank : 50)	NC score	0.058631 (rank : 676)
Query Neighborhood Hits	455	Target Neighborhood Hits	2000	Shared Neighborhood Hits	151
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

SYCP1_MOUSE
θ value	0.0148317 (rank : 51)	NC score	0.101597 (rank : 162)
Query Neighborhood Hits	455	Target Neighborhood Hits	1456	Shared Neighborhood Hits	147
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TITIN_HUMAN
θ value	0.0148317 (rank : 52)	NC score	0.046661 (rank : 876)
Query Neighborhood Hits	455	Target Neighborhood Hits	2923	Shared Neighborhood Hits	204
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

LASP1_MOUSE
θ value	0.0193708 (rank : 53)	NC score	0.213230 (rank : 20)
Query Neighborhood Hits	455	Target Neighborhood Hits	297	Shared Neighborhood Hits	85
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

BARH2_MOUSE
θ value	0.0252991 (rank : 54)	NC score	0.018767 (rank : 975)
Query Neighborhood Hits	455	Target Neighborhood Hits	397	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VIB5, Q66L43	Gene names	Barhl2, Barh1, Mbh1
Domain Architecture	No domain graphic available
Description	BarH-like 2 homeobox protein (Bar-class homeodomain protein MBH1) (Homeobox protein B-H1).

HCLS1_MOUSE
θ value	0.0252991 (rank : 55)	NC score	0.204309 (rank : 25)
Query Neighborhood Hits	455	Target Neighborhood Hits	329	Shared Neighborhood Hits	119
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

SHLB2_HUMAN
θ value	0.0252991 (rank : 56)	NC score	0.127250 (rank : 99)
Query Neighborhood Hits	455	Target Neighborhood Hits	86	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NR46, Q8WY61, Q96JH9	Gene names	SH3GLB2, KIAA1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

DYNA_HUMAN
θ value	0.0330416 (rank : 57)	NC score	0.099457 (rank : 171)
Query Neighborhood Hits	455	Target Neighborhood Hits	1194	Shared Neighborhood Hits	136
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

K0494_MOUSE
θ value	0.0330416 (rank : 58)	NC score	0.108503 (rank : 142)
Query Neighborhood Hits	455	Target Neighborhood Hits	241	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BGQ6, Q3TQN6, Q8BJV7, Q8C0R1	Gene names	Kiaa0494
Domain Architecture	No domain graphic available
Description	Uncharacterized calcium-binding protein KIAA0494.

MOT8_HUMAN
θ value	0.0330416 (rank : 59)	NC score	0.067643 (rank : 487)
Query Neighborhood Hits	455	Target Neighborhood Hits	92	Shared Neighborhood Hits	16
SwissProt Accessions	P36021, Q7Z797	Gene names	SLC16A2, MCT8, XPCT
Domain Architecture	No domain graphic available
Description	Monocarboxylate transporter 8 (MCT 8) (MCT 7) (Solute carrier family 16 member 2) (X-linked PEST-containing transporter).

RGS3_MOUSE
θ value	0.0330416 (rank : 60)	NC score	0.137766 (rank : 75)
Query Neighborhood Hits	455	Target Neighborhood Hits	1621	Shared Neighborhood Hits	210
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

STAM2_MOUSE
θ value	0.0330416 (rank : 61)	NC score	0.196606 (rank : 32)
Query Neighborhood Hits	455	Target Neighborhood Hits	285	Shared Neighborhood Hits	87
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

DDEF1_MOUSE
θ value	0.0431538 (rank : 62)	NC score	0.145151 (rank : 67)
Query Neighborhood Hits	455	Target Neighborhood Hits	592	Shared Neighborhood Hits	109
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

GOGB1_HUMAN
θ value	0.0431538 (rank : 63)	NC score	0.096673 (rank : 182)
Query Neighborhood Hits	455	Target Neighborhood Hits	2297	Shared Neighborhood Hits	195
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

HUWE1_MOUSE
θ value	0.0431538 (rank : 64)	NC score	0.048848 (rank : 862)
Query Neighborhood Hits	455	Target Neighborhood Hits	406	Shared Neighborhood Hits	59
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

SHLB2_MOUSE
θ value	0.0431538 (rank : 65)	NC score	0.125333 (rank : 106)
Query Neighborhood Hits	455	Target Neighborhood Hits	88	Shared Neighborhood Hits	41
SwissProt Accessions	Q8R3V5, Q8K140, Q91ZI7	Gene names	Sh3glb2, Kiaa1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

TACC2_MOUSE
θ value	0.0431538 (rank : 66)	NC score	0.111293 (rank : 134)
Query Neighborhood Hits	455	Target Neighborhood Hits	774	Shared Neighborhood Hits	137
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

ABI1_HUMAN
θ value	0.0563607 (rank : 67)	NC score	0.245997 (rank : 14)
Query Neighborhood Hits	455	Target Neighborhood Hits	257	Shared Neighborhood Hits	95
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

BASP_HUMAN
θ value	0.0563607 (rank : 68)	NC score	0.121689 (rank : 116)
Query Neighborhood Hits	455	Target Neighborhood Hits	321	Shared Neighborhood Hits	60
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

FGR_HUMAN
θ value	0.0563607 (rank : 69)	NC score	0.050756 (rank : 845)
Query Neighborhood Hits	455	Target Neighborhood Hits	1067	Shared Neighborhood Hits	93
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

HOOK3_HUMAN
θ value	0.0563607 (rank : 70)	NC score	0.093212 (rank : 202)
Query Neighborhood Hits	455	Target Neighborhood Hits	1070	Shared Neighborhood Hits	120
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

MARCS_HUMAN
θ value	0.0563607 (rank : 71)	NC score	0.175324 (rank : 46)
Query Neighborhood Hits	455	Target Neighborhood Hits	204	Shared Neighborhood Hits	51
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MUC1_HUMAN
θ value	0.0563607 (rank : 72)	NC score	0.112305 (rank : 133)
Query Neighborhood Hits	455	Target Neighborhood Hits	975	Shared Neighborhood Hits	132
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

ARHGG_MOUSE
θ value	0.0736092 (rank : 73)	NC score	0.131092 (rank : 90)
Query Neighborhood Hits	455	Target Neighborhood Hits	152	Shared Neighborhood Hits	51
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

BASP_MOUSE
θ value	0.0736092 (rank : 74)	NC score	0.155750 (rank : 57)
Query Neighborhood Hits	455	Target Neighborhood Hits	260	Shared Neighborhood Hits	56
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CD2AP_HUMAN
θ value	0.0736092 (rank : 75)	NC score	0.243385 (rank : 16)
Query Neighborhood Hits	455	Target Neighborhood Hits	315	Shared Neighborhood Hits	105
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

CD2AP_MOUSE
θ value	0.0736092 (rank : 76)	NC score	0.245600 (rank : 15)
Query Neighborhood Hits	455	Target Neighborhood Hits	336	Shared Neighborhood Hits	113
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

K1C12_HUMAN
θ value	0.0736092 (rank : 77)	NC score	0.047558 (rank : 873)
Query Neighborhood Hits	455	Target Neighborhood Hits	372	Shared Neighborhood Hits	60
SwissProt Accessions	Q99456	Gene names	KRT12
Domain Architecture
Description	Keratin, type I cytoskeletal 12 (Cytokeratin-12) (CK-12) (Keratin-12) (K12).

MDC1_HUMAN
θ value	0.0736092 (rank : 78)	NC score	0.165192 (rank : 52)
Query Neighborhood Hits	455	Target Neighborhood Hits	1446	Shared Neighborhood Hits	221
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MRCKB_HUMAN
θ value	0.0736092 (rank : 79)	NC score	0.061905 (rank : 610)
Query Neighborhood Hits	455	Target Neighborhood Hits	2239	Shared Neighborhood Hits	178
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

NOL3_MOUSE
θ value	0.0736092 (rank : 80)	NC score	0.080923 (rank : 279)
Query Neighborhood Hits	455	Target Neighborhood Hits	97	Shared Neighborhood Hits	23
SwissProt Accessions	Q9D1X0	Gene names	Nol3
Domain Architecture
Description	Nucleolar protein 3.

PACN3_MOUSE
θ value	0.0736092 (rank : 81)	NC score	0.182360 (rank : 40)
Query Neighborhood Hits	455	Target Neighborhood Hits	380	Shared Neighborhood Hits	109
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

VINEX_HUMAN
θ value	0.0736092 (rank : 82)	NC score	0.199592 (rank : 28)
Query Neighborhood Hits	455	Target Neighborhood Hits	270	Shared Neighborhood Hits	93
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

ASPP1_HUMAN
θ value	0.0961366 (rank : 83)	NC score	0.133956 (rank : 85)
Query Neighborhood Hits	455	Target Neighborhood Hits	956	Shared Neighborhood Hits	180
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

HCLS1_HUMAN
θ value	0.0961366 (rank : 84)	NC score	0.200888 (rank : 27)
Query Neighborhood Hits	455	Target Neighborhood Hits	358	Shared Neighborhood Hits	122
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

ITSN2_MOUSE
θ value	0.0961366 (rank : 85)	NC score	0.171694 (rank : 50)
Query Neighborhood Hits	455	Target Neighborhood Hits	1371	Shared Neighborhood Hits	192
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

LTB1L_HUMAN
θ value	0.0961366 (rank : 86)	NC score	0.035507 (rank : 907)
Query Neighborhood Hits	455	Target Neighborhood Hits	553	Shared Neighborhood Hits	44
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	0.0961366 (rank : 87)	NC score	0.033806 (rank : 911)
Query Neighborhood Hits	455	Target Neighborhood Hits	502	Shared Neighborhood Hits	33
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MINT_MOUSE
θ value	0.0961366 (rank : 88)	NC score	0.117662 (rank : 123)
Query Neighborhood Hits	455	Target Neighborhood Hits	1514	Shared Neighborhood Hits	204
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PRG4_HUMAN
θ value	0.0961366 (rank : 89)	NC score	0.138044 (rank : 73)
Query Neighborhood Hits	455	Target Neighborhood Hits	764	Shared Neighborhood Hits	110
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

ANR18_HUMAN
θ value	0.125558 (rank : 90)	NC score	0.063065 (rank : 598)
Query Neighborhood Hits	455	Target Neighborhood Hits	1106	Shared Neighborhood Hits	111
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ARHG5_HUMAN
θ value	0.125558 (rank : 91)	NC score	0.136332 (rank : 78)
Query Neighborhood Hits	455	Target Neighborhood Hits	172	Shared Neighborhood Hits	56
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

SET1A_HUMAN
θ value	0.125558 (rank : 92)	NC score	0.103432 (rank : 156)
Query Neighborhood Hits	455	Target Neighborhood Hits	690	Shared Neighborhood Hits	85
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SON_MOUSE
θ value	0.125558 (rank : 93)	NC score	0.126531 (rank : 101)
Query Neighborhood Hits	455	Target Neighborhood Hits	957	Shared Neighborhood Hits	132
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

TNR6A_HUMAN
θ value	0.125558 (rank : 94)	NC score	0.057894 (rank : 695)
Query Neighborhood Hits	455	Target Neighborhood Hits	343	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

ZN645_HUMAN
θ value	0.125558 (rank : 95)	NC score	0.104895 (rank : 151)
Query Neighborhood Hits	455	Target Neighborhood Hits	265	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

AHI1_MOUSE
θ value	0.163984 (rank : 96)	NC score	0.136532 (rank : 77)
Query Neighborhood Hits	455	Target Neighborhood Hits	496	Shared Neighborhood Hits	90
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

ARMX2_HUMAN
θ value	0.163984 (rank : 97)	NC score	0.071616 (rank : 424)
Query Neighborhood Hits	455	Target Neighborhood Hits	134	Shared Neighborhood Hits	26
SwissProt Accessions	Q7L311, O60267, Q5H9D9	Gene names	ARMCX2, ALEX2, KIAA0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2 (Protein ALEX2) (ARM protein lost in epithelial cancers on chromosome X 2).

CENPE_HUMAN
θ value	0.163984 (rank : 98)	NC score	0.083880 (rank : 252)
Query Neighborhood Hits	455	Target Neighborhood Hits	2060	Shared Neighborhood Hits	176
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

MY18B_HUMAN
θ value	0.163984 (rank : 99)	NC score	0.088388 (rank : 233)
Query Neighborhood Hits	455	Target Neighborhood Hits	1299	Shared Neighborhood Hits	164
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

MYH11_HUMAN
θ value	0.163984 (rank : 100)	NC score	0.081677 (rank : 272)
Query Neighborhood Hits	455	Target Neighborhood Hits	1806	Shared Neighborhood Hits	171
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

PCLO_HUMAN
θ value	0.163984 (rank : 101)	NC score	0.130946 (rank : 92)
Query Neighborhood Hits	455	Target Neighborhood Hits	2046	Shared Neighborhood Hits	250
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SELPL_MOUSE
θ value	0.163984 (rank : 102)	NC score	0.172783 (rank : 49)
Query Neighborhood Hits	455	Target Neighborhood Hits	588	Shared Neighborhood Hits	134
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SNX5_HUMAN
θ value	0.163984 (rank : 103)	NC score	0.107049 (rank : 146)
Query Neighborhood Hits	455	Target Neighborhood Hits	79	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y5X3, Q52LC4, Q9BWP0	Gene names	SNX5
Domain Architecture
Description	Sorting nexin-5.

SNX5_MOUSE
θ value	0.163984 (rank : 104)	NC score	0.107746 (rank : 143)
Query Neighborhood Hits	455	Target Neighborhood Hits	81	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D8U8, Q543N9	Gene names	Snx5
Domain Architecture
Description	Sorting nexin-5.

CLUL1_HUMAN
θ value	0.21417 (rank : 105)	NC score	0.078901 (rank : 309)
Query Neighborhood Hits	455	Target Neighborhood Hits	62	Shared Neighborhood Hits	15
SwissProt Accessions	Q15846	Gene names	CLUL1
Domain Architecture	No domain graphic available
Description	Clusterin-like protein 1 precursor (Retinal-specific clusterin-like protein).

MLL4_HUMAN
θ value	0.21417 (rank : 106)	NC score	0.093823 (rank : 199)
Query Neighborhood Hits	455	Target Neighborhood Hits	722	Shared Neighborhood Hits	92
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MYT1_MOUSE
θ value	0.21417 (rank : 107)	NC score	0.036623 (rank : 904)
Query Neighborhood Hits	455	Target Neighborhood Hits	385	Shared Neighborhood Hits	55
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

NFM_HUMAN
θ value	0.21417 (rank : 108)	NC score	0.081200 (rank : 275)
Query Neighborhood Hits	455	Target Neighborhood Hits	1328	Shared Neighborhood Hits	190
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

PCLO_MOUSE
θ value	0.21417 (rank : 109)	NC score	0.116332 (rank : 127)
Query Neighborhood Hits	455	Target Neighborhood Hits	2275	Shared Neighborhood Hits	241
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PELP1_HUMAN
θ value	0.21417 (rank : 110)	NC score	0.122437 (rank : 115)
Query Neighborhood Hits	455	Target Neighborhood Hits	596	Shared Neighborhood Hits	104
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

TPM2_HUMAN
θ value	0.21417 (rank : 111)	NC score	0.087339 (rank : 236)
Query Neighborhood Hits	455	Target Neighborhood Hits	677	Shared Neighborhood Hits	94
SwissProt Accessions	P07951, P06468, Q13894, Q53FM4, Q5TCU4, Q5TCU7, Q9UH67	Gene names	TPM2, TMSB
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

ANK2_HUMAN
θ value	0.279714 (rank : 112)	NC score	0.066735 (rank : 503)
Query Neighborhood Hits	455	Target Neighborhood Hits	1615	Shared Neighborhood Hits	188
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

HOOK3_MOUSE
θ value	0.279714 (rank : 113)	NC score	0.089863 (rank : 218)
Query Neighborhood Hits	455	Target Neighborhood Hits	1007	Shared Neighborhood Hits	116
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

HRX_HUMAN
θ value	0.279714 (rank : 114)	NC score	0.077713 (rank : 326)
Query Neighborhood Hits	455	Target Neighborhood Hits	825	Shared Neighborhood Hits	104
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

ITSN2_HUMAN
θ value	0.279714 (rank : 115)	NC score	0.176522 (rank : 45)
Query Neighborhood Hits	455	Target Neighborhood Hits	1173	Shared Neighborhood Hits	183
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

K1C12_MOUSE
θ value	0.279714 (rank : 116)	NC score	0.047224 (rank : 874)
Query Neighborhood Hits	455	Target Neighborhood Hits	409	Shared Neighborhood Hits	68
SwissProt Accessions	Q64291	Gene names	Krt12, Krt1-12, Krt1.12
Domain Architecture
Description	Keratin, type I cytoskeletal 12 (Cytokeratin-12) (CK-12) (Keratin-12) (K12).

MINT_HUMAN
θ value	0.279714 (rank : 117)	NC score	0.110761 (rank : 136)
Query Neighborhood Hits	455	Target Neighborhood Hits	1291	Shared Neighborhood Hits	177
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PACN3_HUMAN
θ value	0.279714 (rank : 118)	NC score	0.179578 (rank : 41)
Query Neighborhood Hits	455	Target Neighborhood Hits	385	Shared Neighborhood Hits	109
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

SMC1A_HUMAN
θ value	0.279714 (rank : 119)	NC score	0.099198 (rank : 172)
Query Neighborhood Hits	455	Target Neighborhood Hits	1346	Shared Neighborhood Hits	149
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
θ value	0.279714 (rank : 120)	NC score	0.099669 (rank : 168)
Query Neighborhood Hits	455	Target Neighborhood Hits	1384	Shared Neighborhood Hits	151
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

GNAS1_MOUSE
θ value	0.365318 (rank : 121)	NC score	0.061604 (rank : 618)
Query Neighborhood Hits	455	Target Neighborhood Hits	651	Shared Neighborhood Hits	96
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

JHD3B_MOUSE
θ value	0.365318 (rank : 122)	NC score	0.028878 (rank : 928)
Query Neighborhood Hits	455	Target Neighborhood Hits	152	Shared Neighborhood Hits	31
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

K1210_HUMAN
θ value	0.365318 (rank : 123)	NC score	0.077172 (rank : 330)
Query Neighborhood Hits	455	Target Neighborhood Hits	219	Shared Neighborhood Hits	37
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

MYH10_MOUSE
θ value	0.365318 (rank : 124)	NC score	0.088703 (rank : 230)
Query Neighborhood Hits	455	Target Neighborhood Hits	1612	Shared Neighborhood Hits	156
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

NELFA_MOUSE
θ value	0.365318 (rank : 125)	NC score	0.079798 (rank : 295)
Query Neighborhood Hits	455	Target Neighborhood Hits	195	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

NFM_MOUSE
θ value	0.365318 (rank : 126)	NC score	0.071724 (rank : 423)
Query Neighborhood Hits	455	Target Neighborhood Hits	1159	Shared Neighborhood Hits	144
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

SPR1A_MOUSE
θ value	0.365318 (rank : 127)	NC score	0.090587 (rank : 213)
Query Neighborhood Hits	455	Target Neighborhood Hits	343	Shared Neighborhood Hits	68
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

TPM2_MOUSE
θ value	0.365318 (rank : 128)	NC score	0.085102 (rank : 245)
Query Neighborhood Hits	455	Target Neighborhood Hits	676	Shared Neighborhood Hits	95
SwissProt Accessions	P58774, P02560, P46901	Gene names	Tpm2, Tpm-2
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

AHI1_HUMAN
θ value	0.47712 (rank : 129)	NC score	0.124375 (rank : 111)
Query Neighborhood Hits	455	Target Neighborhood Hits	537	Shared Neighborhood Hits	93
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

ARHG6_MOUSE
θ value	0.47712 (rank : 130)	NC score	0.151395 (rank : 61)
Query Neighborhood Hits	455	Target Neighborhood Hits	394	Shared Neighborhood Hits	107
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

BCAS1_HUMAN
θ value	0.47712 (rank : 131)	NC score	0.071012 (rank : 430)
Query Neighborhood Hits	455	Target Neighborhood Hits	133	Shared Neighborhood Hits	33
SwissProt Accessions	O75363, Q68CZ3	Gene names	BCAS1, AIBC1, NABC1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 (Novel amplified in breast cancer 1) (Amplified and overexpressed in breast cancer).

BCL9_MOUSE
θ value	0.47712 (rank : 132)	NC score	0.092914 (rank : 206)
Query Neighborhood Hits	455	Target Neighborhood Hits	770	Shared Neighborhood Hits	99
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

INCE_HUMAN
θ value	0.47712 (rank : 133)	NC score	0.101429 (rank : 164)
Query Neighborhood Hits	455	Target Neighborhood Hits	978	Shared Neighborhood Hits	122
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

LTB1L_MOUSE
θ value	0.47712 (rank : 134)	NC score	0.030358 (rank : 919)
Query Neighborhood Hits	455	Target Neighborhood Hits	514	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	0.47712 (rank : 135)	NC score	0.029279 (rank : 927)
Query Neighborhood Hits	455	Target Neighborhood Hits	479	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

NCOR1_MOUSE
θ value	0.47712 (rank : 136)	NC score	0.058380 (rank : 681)
Query Neighborhood Hits	455	Target Neighborhood Hits	521	Shared Neighborhood Hits	79
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

NFH_HUMAN
θ value	0.47712 (rank : 137)	NC score	0.084423 (rank : 248)
Query Neighborhood Hits	455	Target Neighborhood Hits	1242	Shared Neighborhood Hits	167
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NP1L3_MOUSE
θ value	0.47712 (rank : 138)	NC score	0.045817 (rank : 880)
Query Neighborhood Hits	455	Target Neighborhood Hits	233	Shared Neighborhood Hits	46
SwissProt Accessions	Q794H2, O54802	Gene names	Nap1l3, Mb20
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 3 (Brain-specific protein MB20).

PELP1_MOUSE
θ value	0.47712 (rank : 139)	NC score	0.119026 (rank : 120)
Query Neighborhood Hits	455	Target Neighborhood Hits	709	Shared Neighborhood Hits	115
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

SUHW4_MOUSE
θ value	0.47712 (rank : 140)	NC score	0.006681 (rank : 1017)
Query Neighborhood Hits	455	Target Neighborhood Hits	737	Shared Neighborhood Hits	25
SwissProt Accessions	Q68FE8, Q3T9B1, Q8BI82	Gene names	Suhw4
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

TARSH_HUMAN
θ value	0.47712 (rank : 141)	NC score	0.131294 (rank : 88)
Query Neighborhood Hits	455	Target Neighborhood Hits	768	Shared Neighborhood Hits	123
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

BAT3_MOUSE
θ value	0.62314 (rank : 142)	NC score	0.090659 (rank : 212)
Query Neighborhood Hits	455	Target Neighborhood Hits	518	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

BCL9_HUMAN
θ value	0.62314 (rank : 143)	NC score	0.095728 (rank : 188)
Query Neighborhood Hits	455	Target Neighborhood Hits	1008	Shared Neighborhood Hits	124
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CAC1F_MOUSE
θ value	0.62314 (rank : 144)	NC score	0.010763 (rank : 1007)
Query Neighborhood Hits	455	Target Neighborhood Hits	142	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CF010_HUMAN
θ value	0.62314 (rank : 145)	NC score	0.076637 (rank : 346)
Query Neighborhood Hits	455	Target Neighborhood Hits	329	Shared Neighborhood Hits	53
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

CIZ1_HUMAN
θ value	0.62314 (rank : 146)	NC score	0.082144 (rank : 264)
Query Neighborhood Hits	455	Target Neighborhood Hits	359	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

LAMA2_HUMAN
θ value	0.62314 (rank : 147)	NC score	0.042677 (rank : 887)
Query Neighborhood Hits	455	Target Neighborhood Hits	1092	Shared Neighborhood Hits	89
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

MKL2_HUMAN
θ value	0.62314 (rank : 148)	NC score	0.045978 (rank : 878)
Query Neighborhood Hits	455	Target Neighborhood Hits	274	Shared Neighborhood Hits	60
SwissProt Accessions	Q9ULH7, Q68CT1, Q6UB16, Q86WW2, Q8N226	Gene names	MKL2, KIAA1243, MRTFB
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B) (Megakaryoblastic leukemia 2).

MYH10_HUMAN
θ value	0.62314 (rank : 149)	NC score	0.088774 (rank : 229)
Query Neighborhood Hits	455	Target Neighborhood Hits	1620	Shared Neighborhood Hits	157
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

NCK1_HUMAN
θ value	0.62314 (rank : 150)	NC score	0.153075 (rank : 58)
Query Neighborhood Hits	455	Target Neighborhood Hits	312	Shared Neighborhood Hits	87
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

PRG4_MOUSE
θ value	0.62314 (rank : 151)	NC score	0.129563 (rank : 95)
Query Neighborhood Hits	455	Target Neighborhood Hits	624	Shared Neighborhood Hits	97
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SDC1_HUMAN
θ value	0.62314 (rank : 152)	NC score	0.050612 (rank : 850)
Query Neighborhood Hits	455	Target Neighborhood Hits	57	Shared Neighborhood Hits	12
SwissProt Accessions	P18827, Q96HB7	Gene names	SDC1, SDC
Domain Architecture
Description	Syndecan-1 precursor (SYND1) (CD138 antigen).

SH3G1_HUMAN
θ value	0.62314 (rank : 153)	NC score	0.156875 (rank : 56)
Query Neighborhood Hits	455	Target Neighborhood Hits	307	Shared Neighborhood Hits	105
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

SHLB1_HUMAN
θ value	0.62314 (rank : 154)	NC score	0.125943 (rank : 102)
Query Neighborhood Hits	455	Target Neighborhood Hits	96	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y371, Q9H3Z0, Q9NR47, Q9NYA9	Gene names	SH3GLB1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1) (Bax- interacting factor 1) (Bif-1).

SHLB1_MOUSE
θ value	0.62314 (rank : 155)	NC score	0.127739 (rank : 98)
Query Neighborhood Hits	455	Target Neighborhood Hits	101	Shared Neighborhood Hits	52
SwissProt Accessions	Q9JK48, Q8CDS9, Q8VI52, Q9CT31	Gene names	Sh3glb1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1).

ZN692_MOUSE
θ value	0.62314 (rank : 156)	NC score	-0.002485 (rank : 1023)
Query Neighborhood Hits	455	Target Neighborhood Hits	751	Shared Neighborhood Hits	14
SwissProt Accessions	Q3U381	Gene names	Znf692, Zfp692
Domain Architecture	No domain graphic available
Description	Zinc finger protein 692.

ADDA_MOUSE
θ value	0.813845 (rank : 157)	NC score	0.058537 (rank : 680)
Query Neighborhood Hits	455	Target Neighborhood Hits	198	Shared Neighborhood Hits	57
SwissProt Accessions	Q9QYC0, Q9JLE3	Gene names	Add1
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

AMOT_HUMAN
θ value	0.813845 (rank : 158)	NC score	0.095820 (rank : 186)
Query Neighborhood Hits	455	Target Neighborhood Hits	712	Shared Neighborhood Hits	118
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

BPTF_HUMAN
θ value	0.813845 (rank : 159)	NC score	0.067826 (rank : 484)
Query Neighborhood Hits	455	Target Neighborhood Hits	786	Shared Neighborhood Hits	115
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CASC3_MOUSE
θ value	0.813845 (rank : 160)	NC score	0.073114 (rank : 401)
Query Neighborhood Hits	455	Target Neighborhood Hits	333	Shared Neighborhood Hits	70
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

CASZ1_HUMAN
θ value	0.813845 (rank : 161)	NC score	0.033973 (rank : 910)
Query Neighborhood Hits	455	Target Neighborhood Hits	473	Shared Neighborhood Hits	24
SwissProt Accessions	Q86V15, Q5T9S1, Q8WX49, Q8WX50, Q9BT16, Q9NXC6	Gene names	CASZ1, CST, ZNF693
Domain Architecture	No domain graphic available
Description	Castor homolog 1 zinc finger protein (Castor-related protein) (Zinc finger protein 693).

CCD37_HUMAN
θ value	0.813845 (rank : 162)	NC score	0.073387 (rank : 396)
Query Neighborhood Hits	455	Target Neighborhood Hits	248	Shared Neighborhood Hits	50
SwissProt Accessions	Q494V2, Q494V1, Q494V4, Q8N838	Gene names	CCDC37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 37.

CNTP1_HUMAN
θ value	0.813845 (rank : 163)	NC score	0.019821 (rank : 968)
Query Neighborhood Hits	455	Target Neighborhood Hits	196	Shared Neighborhood Hits	17
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

FMNL_HUMAN
θ value	0.813845 (rank : 164)	NC score	0.076422 (rank : 352)
Query Neighborhood Hits	455	Target Neighborhood Hits	529	Shared Neighborhood Hits	93
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

IF4G1_HUMAN
θ value	0.813845 (rank : 165)	NC score	0.060551 (rank : 640)
Query Neighborhood Hits	455	Target Neighborhood Hits	347	Shared Neighborhood Hits	67
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

MYH11_MOUSE
θ value	0.813845 (rank : 166)	NC score	0.089995 (rank : 216)
Query Neighborhood Hits	455	Target Neighborhood Hits	1777	Shared Neighborhood Hits	165
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH9_HUMAN
θ value	0.813845 (rank : 167)	NC score	0.087116 (rank : 239)
Query Neighborhood Hits	455	Target Neighborhood Hits	1762	Shared Neighborhood Hits	167
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYO1E_HUMAN
θ value	0.813845 (rank : 168)	NC score	0.098124 (rank : 175)
Query Neighborhood Hits	455	Target Neighborhood Hits	293	Shared Neighborhood Hits	102
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

PDLI7_HUMAN
θ value	0.813845 (rank : 169)	NC score	0.036739 (rank : 903)
Query Neighborhood Hits	455	Target Neighborhood Hits	547	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

RIMB1_MOUSE
θ value	0.813845 (rank : 170)	NC score	0.119781 (rank : 118)
Query Neighborhood Hits	455	Target Neighborhood Hits	1376	Shared Neighborhood Hits	203
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RTN1_MOUSE
θ value	0.813845 (rank : 171)	NC score	0.056696 (rank : 718)
Query Neighborhood Hits	455	Target Neighborhood Hits	189	Shared Neighborhood Hits	43
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

SPR1B_MOUSE
θ value	0.813845 (rank : 172)	NC score	0.097596 (rank : 179)
Query Neighborhood Hits	455	Target Neighborhood Hits	395	Shared Neighborhood Hits	80
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

SYCP1_HUMAN
θ value	0.813845 (rank : 173)	NC score	0.092371 (rank : 207)
Query Neighborhood Hits	455	Target Neighborhood Hits	1313	Shared Neighborhood Hits	131
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

SYTL1_MOUSE
θ value	0.813845 (rank : 174)	NC score	0.041066 (rank : 892)
Query Neighborhood Hits	455	Target Neighborhood Hits	314	Shared Neighborhood Hits	63
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

TACC2_HUMAN
θ value	0.813845 (rank : 175)	NC score	0.110901 (rank : 135)
Query Neighborhood Hits	455	Target Neighborhood Hits	856	Shared Neighborhood Hits	155
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

ARHG6_HUMAN
θ value	1.06291 (rank : 176)	NC score	0.150532 (rank : 62)
Query Neighborhood Hits	455	Target Neighborhood Hits	376	Shared Neighborhood Hits	111
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

ASPP1_MOUSE
θ value	1.06291 (rank : 177)	NC score	0.148210 (rank : 65)
Query Neighborhood Hits	455	Target Neighborhood Hits	1244	Shared Neighborhood Hits	249
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

AZI1_MOUSE
θ value	1.06291 (rank : 178)	NC score	0.082111 (rank : 265)
Query Neighborhood Hits	455	Target Neighborhood Hits	990	Shared Neighborhood Hits	121
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

BRE1B_HUMAN
θ value	1.06291 (rank : 179)	NC score	0.078701 (rank : 313)
Query Neighborhood Hits	455	Target Neighborhood Hits	1040	Shared Neighborhood Hits	110
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

CSKI1_MOUSE
θ value	1.06291 (rank : 180)	NC score	0.060137 (rank : 655)
Query Neighborhood Hits	455	Target Neighborhood Hits	1031	Shared Neighborhood Hits	130
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI2_HUMAN
θ value	1.06291 (rank : 181)	NC score	0.044538 (rank : 883)
Query Neighborhood Hits	455	Target Neighborhood Hits	747	Shared Neighborhood Hits	81
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CTRO_HUMAN
θ value	1.06291 (rank : 182)	NC score	0.053891 (rank : 778)
Query Neighborhood Hits	455	Target Neighborhood Hits	2092	Shared Neighborhood Hits	165
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CUTL2_HUMAN
θ value	1.06291 (rank : 183)	NC score	0.069645 (rank : 449)
Query Neighborhood Hits	455	Target Neighborhood Hits	906	Shared Neighborhood Hits	115
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

EEA1_MOUSE
θ value	1.06291 (rank : 184)	NC score	0.079491 (rank : 303)
Query Neighborhood Hits	455	Target Neighborhood Hits	1637	Shared Neighborhood Hits	149
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

EP300_HUMAN
θ value	1.06291 (rank : 185)	NC score	0.071360 (rank : 427)
Query Neighborhood Hits	455	Target Neighborhood Hits	821	Shared Neighborhood Hits	103
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

FA38A_HUMAN
θ value	1.06291 (rank : 186)	NC score	0.023682 (rank : 954)
Query Neighborhood Hits	455	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q92508	Gene names	FAM38A, KIAA0233
Domain Architecture	No domain graphic available
Description	Protein FAM38A.

FBLI1_HUMAN
θ value	1.06291 (rank : 187)	NC score	0.028352 (rank : 932)
Query Neighborhood Hits	455	Target Neighborhood Hits	200	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WUP2, Q5VVE0, Q5VVE1, Q8IX23, Q96T00, Q9UFD6	Gene names	FBLIM1, FBLP1
Domain Architecture
Description	Filamin-binding LIM protein 1 (Filamin-binding LIM protein 1) (FBLP-1) (Mitogen-inducible 2-interacting protein) (MIG2-interacting protein) (Migfilin).

GLU2B_HUMAN
θ value	1.06291 (rank : 188)	NC score	0.079894 (rank : 292)
Query Neighborhood Hits	455	Target Neighborhood Hits	377	Shared Neighborhood Hits	64
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

GOGA1_HUMAN
θ value	1.06291 (rank : 189)	NC score	0.085058 (rank : 246)
Query Neighborhood Hits	455	Target Neighborhood Hits	1222	Shared Neighborhood Hits	135
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

MAGD4_HUMAN
θ value	1.06291 (rank : 190)	NC score	0.035677 (rank : 905)
Query Neighborhood Hits	455	Target Neighborhood Hits	338	Shared Neighborhood Hits	70
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

NEST_HUMAN
θ value	1.06291 (rank : 191)	NC score	0.094135 (rank : 195)
Query Neighborhood Hits	455	Target Neighborhood Hits	1305	Shared Neighborhood Hits	163
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

PO121_MOUSE
θ value	1.06291 (rank : 192)	NC score	0.073873 (rank : 385)
Query Neighborhood Hits	455	Target Neighborhood Hits	345	Shared Neighborhood Hits	51
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

PRP8_HUMAN
θ value	1.06291 (rank : 193)	NC score	0.048546 (rank : 865)
Query Neighborhood Hits	455	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	Q6P2Q9, O14547, O75965	Gene names	PRPF8, PRPC8
Domain Architecture	No domain graphic available
Description	Pre-mRNA-processing-splicing factor 8 (Splicing factor Prp8) (PRP8 homolog) (220 kDa U5 snRNP-specific protein) (p220).

PRP8_MOUSE
θ value	1.06291 (rank : 194)	NC score	0.048552 (rank : 864)
Query Neighborhood Hits	455	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	Q99PV0, Q5ND30, Q5ND31, Q7TQK2, Q8BRZ5, Q8K001	Gene names	Prpf8, Prp8
Domain Architecture	No domain graphic available
Description	Pre-mRNA-processing-splicing factor 8 (Splicing factor Prp8).

PTPRG_HUMAN
θ value	1.06291 (rank : 195)	NC score	0.012700 (rank : 999)
Query Neighborhood Hits	455	Target Neighborhood Hits	231	Shared Neighborhood Hits	26
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

SMC2_MOUSE
θ value	1.06291 (rank : 196)	NC score	0.089943 (rank : 217)
Query Neighborhood Hits	455	Target Neighborhood Hits	1131	Shared Neighborhood Hits	127
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

SPTA1_HUMAN
θ value	1.06291 (rank : 197)	NC score	0.089161 (rank : 224)
Query Neighborhood Hits	455	Target Neighborhood Hits	748	Shared Neighborhood Hits	147
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

TRHY_HUMAN
θ value	1.06291 (rank : 198)	NC score	0.076984 (rank : 333)
Query Neighborhood Hits	455	Target Neighborhood Hits	1385	Shared Neighborhood Hits	122
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

CD2L1_HUMAN
θ value	1.38821 (rank : 199)	NC score	0.025487 (rank : 943)
Query Neighborhood Hits	455	Target Neighborhood Hits	1467	Shared Neighborhood Hits	105
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CEL_HUMAN
θ value	1.38821 (rank : 200)	NC score	0.061741 (rank : 614)
Query Neighborhood Hits	455	Target Neighborhood Hits	896	Shared Neighborhood Hits	125
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

JIP3_HUMAN
θ value	1.38821 (rank : 201)	NC score	0.075184 (rank : 366)
Query Neighborhood Hits	455	Target Neighborhood Hits	1039	Shared Neighborhood Hits	156
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

JPH4_MOUSE
θ value	1.38821 (rank : 202)	NC score	0.020000 (rank : 966)
Query Neighborhood Hits	455	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	Q80WT0, Q8BMI1	Gene names	Jph4, Jphl1
Domain Architecture	No domain graphic available
Description	Junctophilin-4 (Junctophilin-like 1 protein).

LRC48_HUMAN
θ value	1.38821 (rank : 203)	NC score	0.039160 (rank : 896)
Query Neighborhood Hits	455	Target Neighborhood Hits	324	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H069, Q86SF9, Q86W73, Q8IWG0	Gene names	LRRC48
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 48.

MDC1_MOUSE
θ value	1.38821 (rank : 204)	NC score	0.141653 (rank : 70)
Query Neighborhood Hits	455	Target Neighborhood Hits	998	Shared Neighborhood Hits	175
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MYBPH_HUMAN
θ value	1.38821 (rank : 205)	NC score	0.024555 (rank : 948)
Query Neighborhood Hits	455	Target Neighborhood Hits	256	Shared Neighborhood Hits	17
SwissProt Accessions	Q13203, Q16886, Q86YC5	Gene names	MYBPH
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

PACN2_HUMAN
θ value	1.38821 (rank : 206)	NC score	0.184266 (rank : 38)
Query Neighborhood Hits	455	Target Neighborhood Hits	339	Shared Neighborhood Hits	107
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PACN2_MOUSE
θ value	1.38821 (rank : 207)	NC score	0.197142 (rank : 31)
Query Neighborhood Hits	455	Target Neighborhood Hits	382	Shared Neighborhood Hits	114
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PHC1_MOUSE
θ value	1.38821 (rank : 208)	NC score	0.043885 (rank : 885)
Query Neighborhood Hits	455	Target Neighborhood Hits	205	Shared Neighborhood Hits	34
SwissProt Accessions	Q64028, P70359, Q64307, Q8BZ80	Gene names	Phc1, Edr, Edr1, Rae28
Domain Architecture
Description	Polyhomeotic-like protein 1 (mPH1) (Early development regulatory protein 1) (RAE-28).

PPIP1_MOUSE
θ value	1.38821 (rank : 209)	NC score	0.186648 (rank : 37)
Query Neighborhood Hits	455	Target Neighborhood Hits	377	Shared Neighborhood Hits	118
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

SH22A_HUMAN
θ value	1.38821 (rank : 210)	NC score	0.035366 (rank : 908)
Query Neighborhood Hits	455	Target Neighborhood Hits	144	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

SHD_MOUSE
θ value	1.38821 (rank : 211)	NC score	0.029653 (rank : 925)
Query Neighborhood Hits	455	Target Neighborhood Hits	137	Shared Neighborhood Hits	19
SwissProt Accessions	O88834, Q3SYI7	Gene names	Shd
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

STS1_MOUSE
θ value	1.38821 (rank : 212)	NC score	0.119750 (rank : 119)
Query Neighborhood Hits	455	Target Neighborhood Hits	104	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BGG7, Q3U8Z2, Q8BMW9	Gene names	Sts1
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

TXLNB_HUMAN
θ value	1.38821 (rank : 213)	NC score	0.087929 (rank : 235)
Query Neighborhood Hits	455	Target Neighborhood Hits	912	Shared Neighborhood Hits	154
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

BRD4_MOUSE
θ value	1.81305 (rank : 214)	NC score	0.069330 (rank : 455)
Query Neighborhood Hits	455	Target Neighborhood Hits	845	Shared Neighborhood Hits	122
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CABYR_HUMAN
θ value	1.81305 (rank : 215)	NC score	0.050803 (rank : 843)
Query Neighborhood Hits	455	Target Neighborhood Hits	87	Shared Neighborhood Hits	22
SwissProt Accessions	O75952, Q8WXW5, Q9HAY3, Q9HAY4, Q9HAY5, Q9HCY9	Gene names	CABYR, CBP86, FSP2
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86) (Fibrousheathin-2) (FSP-2).

ES8L3_MOUSE
θ value	1.81305 (rank : 216)	NC score	0.089153 (rank : 225)
Query Neighborhood Hits	455	Target Neighborhood Hits	168	Shared Neighborhood Hits	69
SwissProt Accessions	Q91WL0, Q3TJ14	Gene names	Eps8l3, Eps8r3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

GP152_HUMAN
θ value	1.81305 (rank : 217)	NC score	0.041249 (rank : 891)
Query Neighborhood Hits	455	Target Neighborhood Hits	636	Shared Neighborhood Hits	73
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

KIF5A_MOUSE
θ value	1.81305 (rank : 218)	NC score	0.052361 (rank : 813)
Query Neighborhood Hits	455	Target Neighborhood Hits	859	Shared Neighborhood Hits	106
SwissProt Accessions	P33175, Q5DTP1, Q6PDY7, Q9Z2F9	Gene names	Kif5a, Kiaa4086, Kif5, Nkhc1
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

MAP2_MOUSE
θ value	1.81305 (rank : 219)	NC score	0.068719 (rank : 466)
Query Neighborhood Hits	455	Target Neighborhood Hits	342	Shared Neighborhood Hits	76
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

MUC7_HUMAN
θ value	1.81305 (rank : 220)	NC score	0.125177 (rank : 107)
Query Neighborhood Hits	455	Target Neighborhood Hits	538	Shared Neighborhood Hits	74
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NCOA2_MOUSE
θ value	1.81305 (rank : 221)	NC score	0.023684 (rank : 953)
Query Neighborhood Hits	455	Target Neighborhood Hits	281	Shared Neighborhood Hits	38
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

NCOA6_HUMAN
θ value	1.81305 (rank : 222)	NC score	0.106547 (rank : 148)
Query Neighborhood Hits	455	Target Neighborhood Hits	1202	Shared Neighborhood Hits	151
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NCOA6_MOUSE
θ value	1.81305 (rank : 223)	NC score	0.105840 (rank : 149)
Query Neighborhood Hits	455	Target Neighborhood Hits	1076	Shared Neighborhood Hits	146
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NEUM_MOUSE
θ value	1.81305 (rank : 224)	NC score	0.067369 (rank : 493)
Query Neighborhood Hits	455	Target Neighborhood Hits	149	Shared Neighborhood Hits	34
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

RTN4_HUMAN
θ value	1.81305 (rank : 225)	NC score	0.073560 (rank : 390)
Query Neighborhood Hits	455	Target Neighborhood Hits	357	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

SAPS1_HUMAN
θ value	1.81305 (rank : 226)	NC score	0.076445 (rank : 350)
Query Neighborhood Hits	455	Target Neighborhood Hits	704	Shared Neighborhood Hits	125
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SC24B_HUMAN
θ value	1.81305 (rank : 227)	NC score	0.031560 (rank : 915)
Query Neighborhood Hits	455	Target Neighborhood Hits	108	Shared Neighborhood Hits	26
SwissProt Accessions	O95487	Gene names	SEC24B
Domain Architecture
Description	Protein transport protein Sec24B (SEC24-related protein B).

SH3G1_MOUSE
θ value	1.81305 (rank : 228)	NC score	0.152682 (rank : 59)
Query Neighborhood Hits	455	Target Neighborhood Hits	291	Shared Neighborhood Hits	99
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

SMC2_HUMAN
θ value	1.81305 (rank : 229)	NC score	0.093313 (rank : 201)
Query Neighborhood Hits	455	Target Neighborhood Hits	1405	Shared Neighborhood Hits	149
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

STS1_HUMAN
θ value	1.81305 (rank : 230)	NC score	0.123713 (rank : 113)
Query Neighborhood Hits	455	Target Neighborhood Hits	106	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TF42, Q53GT5, Q53GT8, Q8NBV7, Q96IG9, Q96NZ2	Gene names	STS1, KIAA1959
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

TAU_MOUSE
θ value	1.81305 (rank : 231)	NC score	0.102050 (rank : 160)
Query Neighborhood Hits	455	Target Neighborhood Hits	502	Shared Neighborhood Hits	87
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TRIO_HUMAN
θ value	1.81305 (rank : 232)	NC score	0.048675 (rank : 863)
Query Neighborhood Hits	455	Target Neighborhood Hits	1580	Shared Neighborhood Hits	135
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

YES_HUMAN
θ value	1.81305 (rank : 233)	NC score	0.047218 (rank : 875)
Query Neighborhood Hits	455	Target Neighborhood Hits	1059	Shared Neighborhood Hits	97
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

3BP1_HUMAN
θ value	2.36792 (rank : 234)	NC score	0.052797 (rank : 803)
Query Neighborhood Hits	455	Target Neighborhood Hits	376	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

BAT2_HUMAN
θ value	2.36792 (rank : 235)	NC score	0.116353 (rank : 126)
Query Neighborhood Hits	455	Target Neighborhood Hits	931	Shared Neighborhood Hits	136
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAT3_HUMAN
θ value	2.36792 (rank : 236)	NC score	0.082180 (rank : 263)
Query Neighborhood Hits	455	Target Neighborhood Hits	490	Shared Neighborhood Hits	75
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BTBD2_HUMAN
θ value	2.36792 (rank : 237)	NC score	0.009852 (rank : 1011)
Query Neighborhood Hits	455	Target Neighborhood Hits	161	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BX70, O60418, O75248, Q7Z5W0, Q96SX8, Q9NPS1, Q9NX81	Gene names	BTBD2
Domain Architecture
Description	BTB/POZ domain-containing protein 2.

CCD21_MOUSE
θ value	2.36792 (rank : 238)	NC score	0.089004 (rank : 228)
Query Neighborhood Hits	455	Target Neighborhood Hits	1135	Shared Neighborhood Hits	138
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CLMN_HUMAN
θ value	2.36792 (rank : 239)	NC score	0.022516 (rank : 958)
Query Neighborhood Hits	455	Target Neighborhood Hits	205	Shared Neighborhood Hits	29
SwissProt Accessions	Q96JQ2, Q9H713, Q9HA23, Q9HA57, Q9UFP4, Q9ULN2	Gene names	CLMN, KIAA1188
Domain Architecture
Description	Calmin.

CSPG3_MOUSE
θ value	2.36792 (rank : 240)	NC score	0.021838 (rank : 963)
Query Neighborhood Hits	455	Target Neighborhood Hits	657	Shared Neighborhood Hits	45
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

GLU2B_MOUSE
θ value	2.36792 (rank : 241)	NC score	0.060155 (rank : 653)
Query Neighborhood Hits	455	Target Neighborhood Hits	357	Shared Neighborhood Hits	59
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

GOGA2_HUMAN
θ value	2.36792 (rank : 242)	NC score	0.073067 (rank : 402)
Query Neighborhood Hits	455	Target Neighborhood Hits	856	Shared Neighborhood Hits	111
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

GOGA5_MOUSE
θ value	2.36792 (rank : 243)	NC score	0.085763 (rank : 243)
Query Neighborhood Hits	455	Target Neighborhood Hits	1434	Shared Neighborhood Hits	150
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

GSCR1_HUMAN
θ value	2.36792 (rank : 244)	NC score	0.100455 (rank : 166)
Query Neighborhood Hits	455	Target Neighborhood Hits	674	Shared Neighborhood Hits	94
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

IF39_MOUSE
θ value	2.36792 (rank : 245)	NC score	0.040401 (rank : 894)
Query Neighborhood Hits	455	Target Neighborhood Hits	206	Shared Neighborhood Hits	34
SwissProt Accessions	Q8JZQ9, Q922K2	Gene names	Eif3s9
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116).

K1802_MOUSE
θ value	2.36792 (rank : 246)	NC score	0.093108 (rank : 204)
Query Neighborhood Hits	455	Target Neighborhood Hits	1596	Shared Neighborhood Hits	158
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

K1C17_MOUSE
θ value	2.36792 (rank : 247)	NC score	0.048440 (rank : 867)
Query Neighborhood Hits	455	Target Neighborhood Hits	456	Shared Neighborhood Hits	73
SwissProt Accessions	Q9QWL7, Q61783	Gene names	Krt17, Krt1-17
Domain Architecture
Description	Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17).

LR37B_HUMAN
θ value	2.36792 (rank : 248)	NC score	0.033738 (rank : 913)
Query Neighborhood Hits	455	Target Neighborhood Hits	392	Shared Neighborhood Hits	41
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

MLL2_HUMAN
θ value	2.36792 (rank : 249)	NC score	0.102561 (rank : 157)
Query Neighborhood Hits	455	Target Neighborhood Hits	1788	Shared Neighborhood Hits	188
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MUC2_HUMAN
θ value	2.36792 (rank : 250)	NC score	0.092973 (rank : 205)
Query Neighborhood Hits	455	Target Neighborhood Hits	906	Shared Neighborhood Hits	104
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MYST3_HUMAN
θ value	2.36792 (rank : 251)	NC score	0.048983 (rank : 861)
Query Neighborhood Hits	455	Target Neighborhood Hits	772	Shared Neighborhood Hits	108
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

NOL10_HUMAN
θ value	2.36792 (rank : 252)	NC score	0.053512 (rank : 788)
Query Neighborhood Hits	455	Target Neighborhood Hits	254	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BSC4, Q53RC9, Q96TA5, Q9H7Y7, Q9H855	Gene names	NOL10
Domain Architecture	No domain graphic available
Description	Nucleolar protein 10.

POLI_HUMAN
θ value	2.36792 (rank : 253)	NC score	0.025359 (rank : 944)
Query Neighborhood Hits	455	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UNA4, Q8N590, Q9H0S1, Q9NYH6	Gene names	POLI, RAD30B
Domain Architecture	No domain graphic available
Description	DNA polymerase iota (EC 2.7.7.7) (RAD30 homolog B) (Eta2).

RTN4_MOUSE
θ value	2.36792 (rank : 254)	NC score	0.080206 (rank : 286)
Query Neighborhood Hits	455	Target Neighborhood Hits	341	Shared Neighborhood Hits	79
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

SM1L2_MOUSE
θ value	2.36792 (rank : 255)	NC score	0.085780 (rank : 242)
Query Neighborhood Hits	455	Target Neighborhood Hits	918	Shared Neighborhood Hits	115
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

SRBS1_HUMAN
θ value	2.36792 (rank : 256)	NC score	0.212510 (rank : 22)
Query Neighborhood Hits	455	Target Neighborhood Hits	396	Shared Neighborhood Hits	113
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRBS1_MOUSE
θ value	2.36792 (rank : 257)	NC score	0.195697 (rank : 33)
Query Neighborhood Hits	455	Target Neighborhood Hits	409	Shared Neighborhood Hits	117
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRC8_HUMAN
θ value	2.36792 (rank : 258)	NC score	0.190223 (rank : 34)
Query Neighborhood Hits	455	Target Neighborhood Hits	269	Shared Neighborhood Hits	85
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

SRRM1_MOUSE
θ value	2.36792 (rank : 259)	NC score	0.125683 (rank : 104)
Query Neighborhood Hits	455	Target Neighborhood Hits	966	Shared Neighborhood Hits	131
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TRI44_HUMAN
θ value	2.36792 (rank : 260)	NC score	0.031059 (rank : 916)
Query Neighborhood Hits	455	Target Neighborhood Hits	393	Shared Neighborhood Hits	45
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TTC3_HUMAN
θ value	2.36792 (rank : 261)	NC score	0.062246 (rank : 606)
Query Neighborhood Hits	455	Target Neighborhood Hits	664	Shared Neighborhood Hits	91
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

TXLNA_HUMAN
θ value	2.36792 (rank : 262)	NC score	0.085205 (rank : 244)
Query Neighborhood Hits	455	Target Neighborhood Hits	982	Shared Neighborhood Hits	133
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

WWP2_HUMAN
θ value	2.36792 (rank : 263)	NC score	0.015917 (rank : 989)
Query Neighborhood Hits	455	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

ATBF1_HUMAN
θ value	3.0926 (rank : 264)	NC score	0.019963 (rank : 967)
Query Neighborhood Hits	455	Target Neighborhood Hits	1547	Shared Neighborhood Hits	92
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

ATF5_MOUSE
θ value	3.0926 (rank : 265)	NC score	0.029820 (rank : 924)
Query Neighborhood Hits	455	Target Neighborhood Hits	62	Shared Neighborhood Hits	9
SwissProt Accessions	O70191, Q58E51, Q99NH6	Gene names	Atf5, Atfx, Nap1
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-5 (Activating transcription factor 5-alpha/beta) (Transcription factor ATFx) (Transcription factor-like protein ODA-10) (BZIP protein ATF7) (NRIF3- associated protein) (NAP1).

CBP_HUMAN
θ value	3.0926 (rank : 266)	NC score	0.076103 (rank : 356)
Query Neighborhood Hits	455	Target Neighborhood Hits	941	Shared Neighborhood Hits	122
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CCD11_MOUSE
θ value	3.0926 (rank : 267)	NC score	0.076640 (rank : 344)
Query Neighborhood Hits	455	Target Neighborhood Hits	498	Shared Neighborhood Hits	74
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CDC5L_MOUSE
θ value	3.0926 (rank : 268)	NC score	0.047716 (rank : 871)
Query Neighborhood Hits	455	Target Neighborhood Hits	205	Shared Neighborhood Hits	38
SwissProt Accessions	Q6A068, Q8K1J9	Gene names	Cdc5l, Kiaa0432
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-related protein (Cdc5-like protein).

CK5P2_MOUSE
θ value	3.0926 (rank : 269)	NC score	0.080911 (rank : 280)
Query Neighborhood Hits	455	Target Neighborhood Hits	1151	Shared Neighborhood Hits	134
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

CS016_HUMAN
θ value	3.0926 (rank : 270)	NC score	0.095464 (rank : 190)
Query Neighborhood Hits	455	Target Neighborhood Hits	310	Shared Neighborhood Hits	59
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

CSPG3_HUMAN
θ value	3.0926 (rank : 271)	NC score	0.023500 (rank : 955)
Query Neighborhood Hits	455	Target Neighborhood Hits	676	Shared Neighborhood Hits	56
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

FA8A1_HUMAN
θ value	3.0926 (rank : 272)	NC score	0.037092 (rank : 900)
Query Neighborhood Hits	455	Target Neighborhood Hits	53	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UBU6	Gene names	FAM8A1, AHCP
Domain Architecture	No domain graphic available
Description	Protein FAM8A1 (Autosomal highly conserved protein).

GR65_HUMAN
θ value	3.0926 (rank : 273)	NC score	0.025006 (rank : 946)
Query Neighborhood Hits	455	Target Neighborhood Hits	148	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BQQ3, Q8N272, Q96H42	Gene names	GORASP1, GRASP65
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5).

HCN2_HUMAN
θ value	3.0926 (rank : 274)	NC score	0.030223 (rank : 922)
Query Neighborhood Hits	455	Target Neighborhood Hits	369	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HDGF_HUMAN
θ value	3.0926 (rank : 275)	NC score	0.022087 (rank : 961)
Query Neighborhood Hits	455	Target Neighborhood Hits	61	Shared Neighborhood Hits	10
SwissProt Accessions	P51858, Q5SZ09	Gene names	HDGF, HMG1L2
Domain Architecture
Description	Hepatoma-derived growth factor (HDGF) (High-mobility group protein 1- like 2) (HMG-1L2).

KIF5C_MOUSE
θ value	3.0926 (rank : 276)	NC score	0.063940 (rank : 580)
Query Neighborhood Hits	455	Target Neighborhood Hits	1040	Shared Neighborhood Hits	130
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

LRRF1_HUMAN
θ value	3.0926 (rank : 277)	NC score	0.078938 (rank : 308)
Query Neighborhood Hits	455	Target Neighborhood Hits	625	Shared Neighborhood Hits	96
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

MADCA_HUMAN
θ value	3.0926 (rank : 278)	NC score	0.078294 (rank : 319)
Query Neighborhood Hits	455	Target Neighborhood Hits	221	Shared Neighborhood Hits	47
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

MAST4_HUMAN
θ value	3.0926 (rank : 279)	NC score	0.040577 (rank : 893)
Query Neighborhood Hits	455	Target Neighborhood Hits	1804	Shared Neighborhood Hits	169
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

NGEF_HUMAN
θ value	3.0926 (rank : 280)	NC score	0.117549 (rank : 124)
Query Neighborhood Hits	455	Target Neighborhood Hits	166	Shared Neighborhood Hits	63
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

NUF2_HUMAN
θ value	3.0926 (rank : 281)	NC score	0.081872 (rank : 271)
Query Neighborhood Hits	455	Target Neighborhood Hits	661	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

PCNT_MOUSE
θ value	3.0926 (rank : 282)	NC score	0.079922 (rank : 291)
Query Neighborhood Hits	455	Target Neighborhood Hits	1207	Shared Neighborhood Hits	133
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

PHF8_HUMAN
θ value	3.0926 (rank : 283)	NC score	0.014396 (rank : 993)
Query Neighborhood Hits	455	Target Neighborhood Hits	105	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UPP1, Q5H9U5, Q5VUJ4, Q7Z6D4, Q9HAH2	Gene names	PHF8, KIAA1111, ZNF422
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

PI51C_HUMAN
θ value	3.0926 (rank : 284)	NC score	0.021834 (rank : 964)
Query Neighborhood Hits	455	Target Neighborhood Hits	109	Shared Neighborhood Hits	29
SwissProt Accessions	O60331, Q7LE07	Gene names	PIP5K1C, KIAA0589
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I gamma) (PtdIns(4)P- 5-kinase gamma) (PtdInsPKIgamma) (PIP5KIgamma).

PLXB1_HUMAN
θ value	3.0926 (rank : 285)	NC score	0.024001 (rank : 950)
Query Neighborhood Hits	455	Target Neighborhood Hits	360	Shared Neighborhood Hits	58
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

RFIP3_HUMAN
θ value	3.0926 (rank : 286)	NC score	0.087215 (rank : 238)
Query Neighborhood Hits	455	Target Neighborhood Hits	1055	Shared Neighborhood Hits	132
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

RUSC1_HUMAN
θ value	3.0926 (rank : 287)	NC score	0.095264 (rank : 192)
Query Neighborhood Hits	455	Target Neighborhood Hits	226	Shared Neighborhood Hits	73
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

S23IP_MOUSE
θ value	3.0926 (rank : 288)	NC score	0.060748 (rank : 636)
Query Neighborhood Hits	455	Target Neighborhood Hits	363	Shared Neighborhood Hits	63
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

SN1L2_HUMAN
θ value	3.0926 (rank : 289)	NC score	0.018737 (rank : 976)
Query Neighborhood Hits	455	Target Neighborhood Hits	964	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H0K1, O94878, Q6AZE2, Q76N03, Q8NCV7, Q96CZ8	Gene names	SNF1LK2, KIAA0781, QIK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Qin- induced kinase).

STAT6_MOUSE
θ value	3.0926 (rank : 290)	NC score	0.011791 (rank : 1006)
Query Neighborhood Hits	455	Target Neighborhood Hits	78	Shared Neighborhood Hits	14
SwissProt Accessions	P52633	Gene names	Stat6
Domain Architecture
Description	Signal transducer and transcription activator 6.

SYNE2_HUMAN
θ value	3.0926 (rank : 291)	NC score	0.067599 (rank : 488)
Query Neighborhood Hits	455	Target Neighborhood Hits	1323	Shared Neighborhood Hits	140
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

UFO_HUMAN
θ value	3.0926 (rank : 292)	NC score	0.021903 (rank : 962)
Query Neighborhood Hits	455	Target Neighborhood Hits	981	Shared Neighborhood Hits	41
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

ZN318_HUMAN
θ value	3.0926 (rank : 293)	NC score	0.054443 (rank : 768)
Query Neighborhood Hits	455	Target Neighborhood Hits	497	Shared Neighborhood Hits	83
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

ADDA_HUMAN
θ value	4.03905 (rank : 294)	NC score	0.032174 (rank : 914)
Query Neighborhood Hits	455	Target Neighborhood Hits	108	Shared Neighborhood Hits	27
SwissProt Accessions	P35611, Q13734, Q14729, Q16156, Q9UJB6	Gene names	ADD1, ADDA
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

AKA12_HUMAN
θ value	4.03905 (rank : 295)	NC score	0.124911 (rank : 108)
Query Neighborhood Hits	455	Target Neighborhood Hits	825	Shared Neighborhood Hits	133
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

APBA3_MOUSE
θ value	4.03905 (rank : 296)	NC score	0.013119 (rank : 997)
Query Neighborhood Hits	455	Target Neighborhood Hits	174	Shared Neighborhood Hits	11
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

ARHGA_MOUSE
θ value	4.03905 (rank : 297)	NC score	0.051064 (rank : 837)
Query Neighborhood Hits	455	Target Neighborhood Hits	125	Shared Neighborhood Hits	28
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ASPP2_HUMAN
θ value	4.03905 (rank : 298)	NC score	0.115574 (rank : 128)
Query Neighborhood Hits	455	Target Neighborhood Hits	1156	Shared Neighborhood Hits	193
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

BSN_MOUSE
θ value	4.03905 (rank : 299)	NC score	0.124835 (rank : 110)
Query Neighborhood Hits	455	Target Neighborhood Hits	2057	Shared Neighborhood Hits	240
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CDC5L_HUMAN
θ value	4.03905 (rank : 300)	NC score	0.044008 (rank : 884)
Query Neighborhood Hits	455	Target Neighborhood Hits	197	Shared Neighborhood Hits	34
SwissProt Accessions	Q99459, Q76N46, Q99974	Gene names	CDC5L, KIAA0432, PCDC5RP
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-like protein (Cdc5-like protein) (Pombe cdc5- related protein).

CLMN_MOUSE
θ value	4.03905 (rank : 301)	NC score	0.026449 (rank : 938)
Query Neighborhood Hits	455	Target Neighborhood Hits	180	Shared Neighborhood Hits	30
SwissProt Accessions	Q8C5W0, Q91V71, Q91XT7, Q91XT8, Q91XU9	Gene names	Clmn
Domain Architecture
Description	Calmin.

CUTL1_HUMAN
θ value	4.03905 (rank : 302)	NC score	0.089534 (rank : 220)
Query Neighborhood Hits	455	Target Neighborhood Hits	1574	Shared Neighborhood Hits	183
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

DDX21_MOUSE
θ value	4.03905 (rank : 303)	NC score	0.016582 (rank : 986)
Query Neighborhood Hits	455	Target Neighborhood Hits	350	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DNL1_HUMAN
θ value	4.03905 (rank : 304)	NC score	0.038306 (rank : 898)
Query Neighborhood Hits	455	Target Neighborhood Hits	216	Shared Neighborhood Hits	45
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

DYSF_MOUSE
θ value	4.03905 (rank : 305)	NC score	0.018679 (rank : 977)
Query Neighborhood Hits	455	Target Neighborhood Hits	162	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

FGR_MOUSE
θ value	4.03905 (rank : 306)	NC score	0.045820 (rank : 879)
Query Neighborhood Hits	455	Target Neighborhood Hits	1069	Shared Neighborhood Hits	96
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FMNL_MOUSE
θ value	4.03905 (rank : 307)	NC score	0.061451 (rank : 624)
Query Neighborhood Hits	455	Target Neighborhood Hits	428	Shared Neighborhood Hits	86
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

GON4L_HUMAN
θ value	4.03905 (rank : 308)	NC score	0.062913 (rank : 599)
Query Neighborhood Hits	455	Target Neighborhood Hits	555	Shared Neighborhood Hits	102
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

HCN4_MOUSE
θ value	4.03905 (rank : 309)	NC score	0.024423 (rank : 949)
Query Neighborhood Hits	455	Target Neighborhood Hits	284	Shared Neighborhood Hits	43
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HECD1_HUMAN
θ value	4.03905 (rank : 310)	NC score	0.023828 (rank : 951)
Query Neighborhood Hits	455	Target Neighborhood Hits	371	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

HMMR_HUMAN
θ value	4.03905 (rank : 311)	NC score	0.078658 (rank : 314)
Query Neighborhood Hits	455	Target Neighborhood Hits	1082	Shared Neighborhood Hits	118
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

KI13B_HUMAN
θ value	4.03905 (rank : 312)	NC score	0.030285 (rank : 921)
Query Neighborhood Hits	455	Target Neighborhood Hits	492	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

LNP_HUMAN
θ value	4.03905 (rank : 313)	NC score	0.025956 (rank : 940)
Query Neighborhood Hits	455	Target Neighborhood Hits	62	Shared Neighborhood Hits	13
SwissProt Accessions	Q9C0E8, Q2M2V8, Q2YD99, Q658W8, Q8N5V9, Q96MS5	Gene names	LNP, KIAA1715
Domain Architecture	No domain graphic available
Description	Protein lunapark.

MEGF9_HUMAN
θ value	4.03905 (rank : 314)	NC score	0.029520 (rank : 926)
Query Neighborhood Hits	455	Target Neighborhood Hits	557	Shared Neighborhood Hits	55
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MYLK_MOUSE
θ value	4.03905 (rank : 315)	NC score	0.030218 (rank : 923)
Query Neighborhood Hits	455	Target Neighborhood Hits	1489	Shared Neighborhood Hits	102
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

PRD16_HUMAN
θ value	4.03905 (rank : 316)	NC score	-0.005138 (rank : 1024)
Query Neighborhood Hits	455	Target Neighborhood Hits	832	Shared Neighborhood Hits	26
SwissProt Accessions	Q9HAZ2, Q8WYJ9, Q9C0I8	Gene names	PRDM16, KIAA1675, MEL1, PFM13
Domain Architecture
Description	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1).

PRRT3_HUMAN
θ value	4.03905 (rank : 317)	NC score	0.140236 (rank : 72)
Query Neighborhood Hits	455	Target Neighborhood Hits	998	Shared Neighborhood Hits	156
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RL1D1_HUMAN
θ value	4.03905 (rank : 318)	NC score	0.065882 (rank : 531)
Query Neighborhood Hits	455	Target Neighborhood Hits	180	Shared Neighborhood Hits	39
SwissProt Accessions	O76021, Q6PL22, Q8IWS7, Q8WUZ1, Q9HDA9, Q9Y3Z9	Gene names	RSL1D1, CATX11, CSIG, PBK1
Domain Architecture	No domain graphic available
Description	Ribosomal L1 domain-containing protein 1 (Cellular senescence- inhibited gene protein) (Protein PBK1) (CATX-11).

SFR15_HUMAN
θ value	4.03905 (rank : 319)	NC score	0.060812 (rank : 633)
Query Neighborhood Hits	455	Target Neighborhood Hits	368	Shared Neighborhood Hits	46
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SGCZ_MOUSE
θ value	4.03905 (rank : 320)	NC score	0.012163 (rank : 1003)
Query Neighborhood Hits	455	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BX51, Q3UVZ2, Q8K1E7	Gene names	Sgcz
Domain Architecture
Description	Zeta-sarcoglycan (Zeta-SG) (ZSG1).

TCEA2_HUMAN
θ value	4.03905 (rank : 321)	NC score	0.019338 (rank : 971)
Query Neighborhood Hits	455	Target Neighborhood Hits	81	Shared Neighborhood Hits	6
SwissProt Accessions	Q15560, Q8TD37, Q8TD38	Gene names	TCEA2
Domain Architecture
Description	Transcription elongation factor A protein 2 (Transcription elongation factor S-II protein 2) (Testis-specific S-II) (Transcription elongation factor TFIIS.l).

TCOF_HUMAN
θ value	4.03905 (rank : 322)	NC score	0.089039 (rank : 227)
Query Neighborhood Hits	455	Target Neighborhood Hits	543	Shared Neighborhood Hits	85
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TCOF_MOUSE
θ value	4.03905 (rank : 323)	NC score	0.096208 (rank : 185)
Query Neighborhood Hits	455	Target Neighborhood Hits	471	Shared Neighborhood Hits	77
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TPR_HUMAN
θ value	4.03905 (rank : 324)	NC score	0.082078 (rank : 266)
Query Neighborhood Hits	455	Target Neighborhood Hits	1921	Shared Neighborhood Hits	176
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

WIRE_MOUSE
θ value	4.03905 (rank : 325)	NC score	0.072160 (rank : 418)
Query Neighborhood Hits	455	Target Neighborhood Hits	310	Shared Neighborhood Hits	50
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

AFF4_HUMAN
θ value	5.27518 (rank : 326)	NC score	0.039600 (rank : 895)
Query Neighborhood Hits	455	Target Neighborhood Hits	611	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

ATBF1_MOUSE
θ value	5.27518 (rank : 327)	NC score	0.025755 (rank : 941)
Query Neighborhood Hits	455	Target Neighborhood Hits	1841	Shared Neighborhood Hits	127
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

BAT2_MOUSE
θ value	5.27518 (rank : 328)	NC score	0.091372 (rank : 211)
Query Neighborhood Hits	455	Target Neighborhood Hits	947	Shared Neighborhood Hits	142
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CAC1H_HUMAN
θ value	5.27518 (rank : 329)	NC score	0.017325 (rank : 979)
Query Neighborhood Hits	455	Target Neighborhood Hits	307	Shared Neighborhood Hits	35
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CD2L2_HUMAN
θ value	5.27518 (rank : 330)	NC score	0.022982 (rank : 957)
Query Neighborhood Hits	455	Target Neighborhood Hits	1439	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

CTRO_MOUSE
θ value	5.27518 (rank : 331)	NC score	0.055227 (rank : 751)
Query Neighborhood Hits	455	Target Neighborhood Hits	2344	Shared Neighborhood Hits	176
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CUTL2_MOUSE
θ value	5.27518 (rank : 332)	NC score	0.056778 (rank : 714)
Query Neighborhood Hits	455	Target Neighborhood Hits	771	Shared Neighborhood Hits	94
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

EP400_HUMAN
θ value	5.27518 (rank : 333)	NC score	0.036926 (rank : 902)
Query Neighborhood Hits	455	Target Neighborhood Hits	556	Shared Neighborhood Hits	70
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

FA40B_MOUSE
θ value	5.27518 (rank : 334)	NC score	0.010469 (rank : 1008)
Query Neighborhood Hits	455	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C9H6, Q3TQB7, Q80TI6, Q8C7A2	Gene names	Fam40b, Kiaa1170
Domain Architecture	No domain graphic available
Description	Protein FAM40B.

FYN_HUMAN
θ value	5.27518 (rank : 335)	NC score	0.047570 (rank : 872)
Query Neighborhood Hits	455	Target Neighborhood Hits	1078	Shared Neighborhood Hits	96
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

FYN_MOUSE
θ value	5.27518 (rank : 336)	NC score	0.047801 (rank : 869)
Query Neighborhood Hits	455	Target Neighborhood Hits	1073	Shared Neighborhood Hits	96
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

GON4L_MOUSE
θ value	5.27518 (rank : 337)	NC score	0.060380 (rank : 645)
Query Neighborhood Hits	455	Target Neighborhood Hits	455	Shared Neighborhood Hits	85
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

INCE_MOUSE
θ value	5.27518 (rank : 338)	NC score	0.081321 (rank : 274)
Query Neighborhood Hits	455	Target Neighborhood Hits	903	Shared Neighborhood Hits	104
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

IWS1_MOUSE
θ value	5.27518 (rank : 339)	NC score	0.100759 (rank : 165)
Query Neighborhood Hits	455	Target Neighborhood Hits	1258	Shared Neighborhood Hits	169
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

K1C15_HUMAN
θ value	5.27518 (rank : 340)	NC score	0.038175 (rank : 899)
Query Neighborhood Hits	455	Target Neighborhood Hits	367	Shared Neighborhood Hits	61
SwissProt Accessions	P19012, Q53XV8, Q9BUG4	Gene names	KRT15, KRTB
Domain Architecture
Description	Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15).

KIF5A_HUMAN
θ value	5.27518 (rank : 341)	NC score	0.050389 (rank : 852)
Query Neighborhood Hits	455	Target Neighborhood Hits	843	Shared Neighborhood Hits	105
SwissProt Accessions	Q12840, Q4LE26	Gene names	KIF5A, NKHC1
Domain Architecture
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

LRC48_MOUSE
θ value	5.27518 (rank : 342)	NC score	0.028409 (rank : 930)
Query Neighborhood Hits	455	Target Neighborhood Hits	252	Shared Neighborhood Hits	21
SwissProt Accessions	Q9D5E4	Gene names	Lrrc48
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 48.

LYPD3_HUMAN
θ value	5.27518 (rank : 343)	NC score	0.019169 (rank : 972)
Query Neighborhood Hits	455	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	O95274, Q9UJ74	Gene names	LYPD3, C4.4A
Domain Architecture	No domain graphic available
Description	Ly6/PLAUR domain-containing protein 3 precursor (GPI-anchored metastasis-associated protein C4.4A homolog) (Matrigel-induced gene C4 protein) (MIG-C4).

M3K4_MOUSE
θ value	5.27518 (rank : 344)	NC score	0.017752 (rank : 978)
Query Neighborhood Hits	455	Target Neighborhood Hits	924	Shared Neighborhood Hits	44
SwissProt Accessions	O08648, O08649, O70124	Gene names	Map3k4, Mekk4
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4).

MDN1_HUMAN
θ value	5.27518 (rank : 345)	NC score	0.048502 (rank : 866)
Query Neighborhood Hits	455	Target Neighborhood Hits	662	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

NCF2_HUMAN
θ value	5.27518 (rank : 346)	NC score	0.199056 (rank : 29)
Query Neighborhood Hits	455	Target Neighborhood Hits	229	Shared Neighborhood Hits	80
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

NGEF_MOUSE
θ value	5.27518 (rank : 347)	NC score	0.114842 (rank : 129)
Query Neighborhood Hits	455	Target Neighborhood Hits	228	Shared Neighborhood Hits	74
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

NU153_HUMAN
θ value	5.27518 (rank : 348)	NC score	0.030650 (rank : 917)
Query Neighborhood Hits	455	Target Neighborhood Hits	227	Shared Neighborhood Hits	28
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

PEPL_HUMAN
θ value	5.27518 (rank : 349)	NC score	0.069421 (rank : 453)
Query Neighborhood Hits	455	Target Neighborhood Hits	1141	Shared Neighborhood Hits	120
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

PHAR2_HUMAN
θ value	5.27518 (rank : 350)	NC score	0.038549 (rank : 897)
Query Neighborhood Hits	455	Target Neighborhood Hits	208	Shared Neighborhood Hits	31
SwissProt Accessions	O75167, Q68DM2	Gene names	PHACTR2, C6orf56, KIAA0680
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 2.

PICA_MOUSE
θ value	5.27518 (rank : 351)	NC score	0.018907 (rank : 974)
Query Neighborhood Hits	455	Target Neighborhood Hits	63	Shared Neighborhood Hits	12
SwissProt Accessions	Q7M6Y3, Q3TS04, Q811P1, Q8BUF6, Q8CIH8, Q8R0A9, Q8R3E1, Q8VDN5, Q921L0	Gene names	Picalm, Calm, Fit1
Domain Architecture
Description	Phosphatidylinositol-binding clathrin assembly protein (Clathrin assembly lymphoid myeloid leukemia) (CALM).

PO6F2_MOUSE
θ value	5.27518 (rank : 352)	NC score	0.023772 (rank : 952)
Query Neighborhood Hits	455	Target Neighborhood Hits	639	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

PRR12_HUMAN
θ value	5.27518 (rank : 353)	NC score	0.110307 (rank : 137)
Query Neighborhood Hits	455	Target Neighborhood Hits	460	Shared Neighborhood Hits	78
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PTPRG_MOUSE
θ value	5.27518 (rank : 354)	NC score	0.013919 (rank : 995)
Query Neighborhood Hits	455	Target Neighborhood Hits	260	Shared Neighborhood Hits	30
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

RAI1_MOUSE
θ value	5.27518 (rank : 355)	NC score	0.041546 (rank : 890)
Query Neighborhood Hits	455	Target Neighborhood Hits	344	Shared Neighborhood Hits	53
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

REPS1_HUMAN
θ value	5.27518 (rank : 356)	NC score	0.053068 (rank : 799)
Query Neighborhood Hits	455	Target Neighborhood Hits	205	Shared Neighborhood Hits	47
SwissProt Accessions	Q96D71, Q8NDR7, Q8WU62, Q9BXY9	Gene names	REPS1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

RIN3_MOUSE
θ value	5.27518 (rank : 357)	NC score	0.046594 (rank : 877)
Query Neighborhood Hits	455	Target Neighborhood Hits	239	Shared Neighborhood Hits	45
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RUNX1_HUMAN
θ value	5.27518 (rank : 358)	NC score	0.019585 (rank : 969)
Query Neighborhood Hits	455	Target Neighborhood Hits	94	Shared Neighborhood Hits	11
SwissProt Accessions	Q01196, O60472, O60473, O76047, O76089, Q13081, Q13755, Q13756, Q13757, Q13758, Q13759, Q15341, Q15343, Q16122, Q16284, Q16285, Q16286, Q16346, Q16347, Q92479	Gene names	RUNX1, AML1, CBFA2
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

RYR1_HUMAN
θ value	5.27518 (rank : 359)	NC score	0.019499 (rank : 970)
Query Neighborhood Hits	455	Target Neighborhood Hits	303	Shared Neighborhood Hits	43
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

SLK_MOUSE
θ value	5.27518 (rank : 360)	NC score	0.033755 (rank : 912)
Query Neighborhood Hits	455	Target Neighborhood Hits	1798	Shared Neighborhood Hits	141
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

SREC2_MOUSE
θ value	5.27518 (rank : 361)	NC score	0.028377 (rank : 931)
Query Neighborhood Hits	455	Target Neighborhood Hits	605	Shared Neighborhood Hits	46
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

VGF_HUMAN
θ value	5.27518 (rank : 362)	NC score	0.054926 (rank : 758)
Query Neighborhood Hits	455	Target Neighborhood Hits	167	Shared Neighborhood Hits	35
SwissProt Accessions	O15240	Gene names	VGF
Domain Architecture	No domain graphic available
Description	Neurosecretory protein VGF precursor.

VINC_HUMAN
θ value	5.27518 (rank : 363)	NC score	0.023414 (rank : 956)
Query Neighborhood Hits	455	Target Neighborhood Hits	145	Shared Neighborhood Hits	28
SwissProt Accessions	P18206, Q16450, Q5SWX2, Q7Z3B8, Q8IXU7	Gene names	VCL
Domain Architecture
Description	Vinculin (Metavinculin).

VINEX_MOUSE
θ value	5.27518 (rank : 364)	NC score	0.184044 (rank : 39)
Query Neighborhood Hits	455	Target Neighborhood Hits	286	Shared Neighborhood Hits	93
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

WIRE_HUMAN
θ value	5.27518 (rank : 365)	NC score	0.074910 (rank : 375)
Query Neighborhood Hits	455	Target Neighborhood Hits	329	Shared Neighborhood Hits	53
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

ASXL1_MOUSE
θ value	6.88961 (rank : 366)	NC score	0.026617 (rank : 936)
Query Neighborhood Hits	455	Target Neighborhood Hits	182	Shared Neighborhood Hits	34
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

BARH2_HUMAN
θ value	6.88961 (rank : 367)	NC score	0.011969 (rank : 1004)
Query Neighborhood Hits	455	Target Neighborhood Hits	419	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NY43, Q7Z4N7	Gene names	BARHL2
Domain Architecture
Description	BarH-like 2 homeobox protein.

BHLH3_MOUSE
θ value	6.88961 (rank : 368)	NC score	0.012259 (rank : 1002)
Query Neighborhood Hits	455	Target Neighborhood Hits	70	Shared Neighborhood Hits	7
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

BIRC7_HUMAN
θ value	6.88961 (rank : 369)	NC score	0.005801 (rank : 1019)
Query Neighborhood Hits	455	Target Neighborhood Hits	185	Shared Neighborhood Hits	6
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

CABYR_MOUSE
θ value	6.88961 (rank : 370)	NC score	0.044972 (rank : 882)
Query Neighborhood Hits	455	Target Neighborhood Hits	80	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D424, Q91Y41, Q91Y42	Gene names	Cabyr, Cbp86
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86).

CCD25_MOUSE
θ value	6.88961 (rank : 371)	NC score	0.028636 (rank : 929)
Query Neighborhood Hits	455	Target Neighborhood Hits	45	Shared Neighborhood Hits	12
SwissProt Accessions	Q78PG9, Q9CSQ8, Q9CUF8	Gene names	Ccdc25
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 25.

CCD37_MOUSE
θ value	6.88961 (rank : 372)	NC score	0.049436 (rank : 860)
Query Neighborhood Hits	455	Target Neighborhood Hits	199	Shared Neighborhood Hits	41
SwissProt Accessions	Q80VN0, Q6AXD6	Gene names	Ccdc37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 37.

CING_HUMAN
θ value	6.88961 (rank : 373)	NC score	0.081192 (rank : 276)
Query Neighborhood Hits	455	Target Neighborhood Hits	1275	Shared Neighborhood Hits	139
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CRKL_HUMAN
θ value	6.88961 (rank : 374)	NC score	0.102457 (rank : 158)
Query Neighborhood Hits	455	Target Neighborhood Hits	313	Shared Neighborhood Hits	77
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

CSF1_HUMAN
θ value	6.88961 (rank : 375)	NC score	0.042350 (rank : 888)
Query Neighborhood Hits	455	Target Neighborhood Hits	258	Shared Neighborhood Hits	46
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

DDX50_MOUSE
θ value	6.88961 (rank : 376)	NC score	0.004488 (rank : 1021)
Query Neighborhood Hits	455	Target Neighborhood Hits	137	Shared Neighborhood Hits	8
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DMD_HUMAN
θ value	6.88961 (rank : 377)	NC score	0.073514 (rank : 392)
Query Neighborhood Hits	455	Target Neighborhood Hits	1135	Shared Neighborhood Hits	119
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

ENAH_MOUSE
θ value	6.88961 (rank : 378)	NC score	0.089097 (rank : 226)
Query Neighborhood Hits	455	Target Neighborhood Hits	919	Shared Neighborhood Hits	132
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

GASP2_MOUSE
θ value	6.88961 (rank : 379)	NC score	0.027671 (rank : 933)
Query Neighborhood Hits	455	Target Neighborhood Hits	228	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BUY8	Gene names	Gprasp2
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 2 (GASP-2).

GEMI5_MOUSE
θ value	6.88961 (rank : 380)	NC score	0.009783 (rank : 1012)
Query Neighborhood Hits	455	Target Neighborhood Hits	424	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BX17	Gene names	Gemin5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

GNAS1_HUMAN
θ value	6.88961 (rank : 381)	NC score	0.030327 (rank : 920)
Query Neighborhood Hits	455	Target Neighborhood Hits	278	Shared Neighborhood Hits	42
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

GP1BA_HUMAN
θ value	6.88961 (rank : 382)	NC score	0.012980 (rank : 998)
Query Neighborhood Hits	455	Target Neighborhood Hits	407	Shared Neighborhood Hits	32
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

GRAP2_MOUSE
θ value	6.88961 (rank : 383)	NC score	0.143836 (rank : 69)
Query Neighborhood Hits	455	Target Neighborhood Hits	297	Shared Neighborhood Hits	85
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

HXA3_MOUSE
θ value	6.88961 (rank : 384)	NC score	0.017161 (rank : 980)
Query Neighborhood Hits	455	Target Neighborhood Hits	558	Shared Neighborhood Hits	61
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

IFIT5_HUMAN
θ value	6.88961 (rank : 385)	NC score	0.015677 (rank : 990)
Query Neighborhood Hits	455	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q13325	Gene names	IFIT5, RI58
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 5 (IFIT-5) (Retinoic acid- and interferon-inducible 58 kDa protein).

K1949_MOUSE
θ value	6.88961 (rank : 386)	NC score	0.026611 (rank : 937)
Query Neighborhood Hits	455	Target Neighborhood Hits	134	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BQ30, Q3UDS6, Q8CEY9, Q8R3D8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1949 homolog.

K1C10_HUMAN
θ value	6.88961 (rank : 387)	NC score	0.045086 (rank : 881)
Query Neighborhood Hits	455	Target Neighborhood Hits	526	Shared Neighborhood Hits	80
SwissProt Accessions	P13645, Q14664, Q8N175	Gene names	KRT10
Domain Architecture
Description	Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10).

MARE1_MOUSE
θ value	6.88961 (rank : 388)	NC score	0.008510 (rank : 1014)
Query Neighborhood Hits	455	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q61166, Q7TN34	Gene names	Mapre1
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein RP/EB family member 1 (APC-binding protein EB1) (End-binding protein 1) (EB1).

MEPD_HUMAN
θ value	6.88961 (rank : 389)	NC score	0.015511 (rank : 991)
Query Neighborhood Hits	455	Target Neighborhood Hits	39	Shared Neighborhood Hits	10
SwissProt Accessions	P52888, Q9UCB3	Gene names	THOP1
Domain Architecture
Description	Thimet oligopeptidase (EC 3.4.24.15) (Endopeptidase 24.15) (MP78).

MINK1_MOUSE
θ value	6.88961 (rank : 390)	NC score	0.027000 (rank : 934)
Query Neighborhood Hits	455	Target Neighborhood Hits	1451	Shared Neighborhood Hits	114
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MYH14_MOUSE
θ value	6.88961 (rank : 391)	NC score	0.069786 (rank : 445)
Query Neighborhood Hits	455	Target Neighborhood Hits	1225	Shared Neighborhood Hits	129
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH6_MOUSE
θ value	6.88961 (rank : 392)	NC score	0.065736 (rank : 534)
Query Neighborhood Hits	455	Target Neighborhood Hits	1501	Shared Neighborhood Hits	145
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYO15_HUMAN
θ value	6.88961 (rank : 393)	NC score	0.047772 (rank : 870)
Query Neighborhood Hits	455	Target Neighborhood Hits	671	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

MYOM1_MOUSE
θ value	6.88961 (rank : 394)	NC score	0.016758 (rank : 985)
Query Neighborhood Hits	455	Target Neighborhood Hits	415	Shared Neighborhood Hits	24
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

NASP_HUMAN
θ value	6.88961 (rank : 395)	NC score	0.091603 (rank : 210)
Query Neighborhood Hits	455	Target Neighborhood Hits	709	Shared Neighborhood Hits	116
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

NCOR2_MOUSE
θ value	6.88961 (rank : 396)	NC score	0.065144 (rank : 548)
Query Neighborhood Hits	455	Target Neighborhood Hits	790	Shared Neighborhood Hits	118
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

NF2L2_MOUSE
θ value	6.88961 (rank : 397)	NC score	0.025695 (rank : 942)
Query Neighborhood Hits	455	Target Neighborhood Hits	183	Shared Neighborhood Hits	31
SwissProt Accessions	Q60795	Gene names	Nfe2l2, Nrf-2, Nrf2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2).

PACN1_HUMAN
θ value	6.88961 (rank : 398)	NC score	0.174513 (rank : 47)
Query Neighborhood Hits	455	Target Neighborhood Hits	320	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN1_MOUSE
θ value	6.88961 (rank : 399)	NC score	0.176617 (rank : 44)
Query Neighborhood Hits	455	Target Neighborhood Hits	283	Shared Neighborhood Hits	100
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PICAL_HUMAN
θ value	6.88961 (rank : 400)	NC score	0.016860 (rank : 983)
Query Neighborhood Hits	455	Target Neighborhood Hits	57	Shared Neighborhood Hits	8
SwissProt Accessions	Q13492, O60700, Q86XZ9	Gene names	PICALM, CALM
Domain Architecture
Description	Phosphatidylinositol-binding clathrin assembly protein (Clathrin assembly lymphoid myeloid leukemia protein).

POLK_MOUSE
θ value	6.88961 (rank : 401)	NC score	0.015992 (rank : 988)
Query Neighborhood Hits	455	Target Neighborhood Hits	66	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QUG2, Q7TPY7	Gene names	Polk, Dinb1
Domain Architecture	No domain graphic available
Description	DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP).

PPIP1_HUMAN
θ value	6.88961 (rank : 402)	NC score	0.173912 (rank : 48)
Query Neighborhood Hits	455	Target Neighborhood Hits	389	Shared Neighborhood Hits	118
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

PTN23_HUMAN
θ value	6.88961 (rank : 403)	NC score	0.041857 (rank : 889)
Query Neighborhood Hits	455	Target Neighborhood Hits	646	Shared Neighborhood Hits	102
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTPRS_HUMAN
θ value	6.88961 (rank : 404)	NC score	0.006493 (rank : 1018)
Query Neighborhood Hits	455	Target Neighborhood Hits	472	Shared Neighborhood Hits	19
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

RPGR1_MOUSE
θ value	6.88961 (rank : 405)	NC score	0.056531 (rank : 724)
Query Neighborhood Hits	455	Target Neighborhood Hits	713	Shared Neighborhood Hits	94
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

RTN1_HUMAN
θ value	6.88961 (rank : 406)	NC score	0.048124 (rank : 868)
Query Neighborhood Hits	455	Target Neighborhood Hits	173	Shared Neighborhood Hits	35
SwissProt Accessions	Q16799, Q16800, Q16801	Gene names	RTN1, NSP
Domain Architecture
Description	Reticulon-1 (Neuroendocrine-specific protein).

SLAP1_MOUSE
θ value	6.88961 (rank : 407)	NC score	0.043121 (rank : 886)
Query Neighborhood Hits	455	Target Neighborhood Hits	117	Shared Neighborhood Hits	16
SwissProt Accessions	Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8	Gene names	Sla, Slap, Slap1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (mSLAP).

SMOO_HUMAN
θ value	6.88961 (rank : 408)	NC score	0.051680 (rank : 822)
Query Neighborhood Hits	455	Target Neighborhood Hits	391	Shared Neighborhood Hits	69
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

TSYL1_MOUSE
θ value	6.88961 (rank : 409)	NC score	0.026158 (rank : 939)
Query Neighborhood Hits	455	Target Neighborhood Hits	105	Shared Neighborhood Hits	23
SwissProt Accessions	O88852, Q3TKW0	Gene names	Tspyl1, Tspyl
Domain Architecture
Description	Testis-specific Y-encoded-like protein 1 (TSPY-like 1).

ABCF1_MOUSE
θ value	8.99809 (rank : 410)	NC score	0.024603 (rank : 947)
Query Neighborhood Hits	455	Target Neighborhood Hits	321	Shared Neighborhood Hits	39
SwissProt Accessions	Q6P542, Q6NV71	Gene names	Abcf1
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1.

ABL1_HUMAN
θ value	8.99809 (rank : 411)	NC score	0.037072 (rank : 901)
Query Neighborhood Hits	455	Target Neighborhood Hits	1220	Shared Neighborhood Hits	111
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ARI3A_HUMAN
θ value	8.99809 (rank : 412)	NC score	0.014355 (rank : 994)
Query Neighborhood Hits	455	Target Neighborhood Hits	80	Shared Neighborhood Hits	12
SwissProt Accessions	Q99856, Q8IZA7	Gene names	ARID3A, DRIL1, DRX, E2FBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 3A (ARID domain- containing protein 3A) (B-cell regulator of IgH transcription) (Bright) (E2F-binding protein 1).

BAG3_HUMAN
θ value	8.99809 (rank : 413)	NC score	0.065394 (rank : 543)
Query Neighborhood Hits	455	Target Neighborhood Hits	314	Shared Neighborhood Hits	69
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

BAIP2_HUMAN
θ value	8.99809 (rank : 414)	NC score	0.055518 (rank : 744)
Query Neighborhood Hits	455	Target Neighborhood Hits	192	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43	Gene names	BAIAP2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Protein BAP2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor substrate p53/p58) (IRSp53/58) (IRS-58) (Fas ligand-associated factor 3) (FLAF3).

CBX6_HUMAN
θ value	8.99809 (rank : 415)	NC score	0.022389 (rank : 959)
Query Neighborhood Hits	455	Target Neighborhood Hits	104	Shared Neighborhood Hits	24
SwissProt Accessions	O95503, Q96EM5	Gene names	CBX6
Domain Architecture
Description	Chromobox protein homolog 6.

CCD46_MOUSE
θ value	8.99809 (rank : 416)	NC score	0.083738 (rank : 253)
Query Neighborhood Hits	455	Target Neighborhood Hits	1405	Shared Neighborhood Hits	160
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CFDP1_HUMAN
θ value	8.99809 (rank : 417)	NC score	0.019095 (rank : 973)
Query Neighborhood Hits	455	Target Neighborhood Hits	80	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UEE9, O00393, O00404, Q9UEF0, Q9UEF1, Q9UEF8	Gene names	CFDP1, BCNT
Domain Architecture	No domain graphic available
Description	Craniofacial development protein 1 (Bucentaur).

CIC_HUMAN
θ value	8.99809 (rank : 418)	NC score	0.071562 (rank : 425)
Query Neighborhood Hits	455	Target Neighborhood Hits	992	Shared Neighborhood Hits	131
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CT2NL_MOUSE
θ value	8.99809 (rank : 419)	NC score	0.074543 (rank : 378)
Query Neighborhood Hits	455	Target Neighborhood Hits	902	Shared Neighborhood Hits	125
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

DAXX_MOUSE
θ value	8.99809 (rank : 420)	NC score	0.016853 (rank : 984)
Query Neighborhood Hits	455	Target Neighborhood Hits	173	Shared Neighborhood Hits	17
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

DJBP_HUMAN
θ value	8.99809 (rank : 421)	NC score	0.010035 (rank : 1009)
Query Neighborhood Hits	455	Target Neighborhood Hits	156	Shared Neighborhood Hits	7
SwissProt Accessions	Q5THR3, Q5U5T6, Q9BY88, Q9H5C4, Q9NSF5	Gene names	DJBP, KIAA1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein (CAP-binding protein complex-interacting protein 1).

ENV2_MOUSE
θ value	8.99809 (rank : 422)	NC score	0.012693 (rank : 1000)
Query Neighborhood Hits	455	Target Neighborhood Hits	39	Shared Neighborhood Hits	11
SwissProt Accessions	P11370, Q61529	Gene names	Fv4, Env
Domain Architecture
Description	Retrovirus-related Env polyprotein from Fv-4 locus.

EP400_MOUSE
θ value	8.99809 (rank : 423)	NC score	0.035606 (rank : 906)
Query Neighborhood Hits	455	Target Neighborhood Hits	592	Shared Neighborhood Hits	88
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

FOXC2_HUMAN
θ value	8.99809 (rank : 424)	NC score	0.006820 (rank : 1016)
Query Neighborhood Hits	455	Target Neighborhood Hits	236	Shared Neighborhood Hits	32
SwissProt Accessions	Q99958	Gene names	FOXC2, FKHL14, MFH1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

FYCO1_HUMAN
θ value	8.99809 (rank : 425)	NC score	0.065221 (rank : 547)
Query Neighborhood Hits	455	Target Neighborhood Hits	1149	Shared Neighborhood Hits	122
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

GOGA3_MOUSE
θ value	8.99809 (rank : 426)	NC score	0.078461 (rank : 317)
Query Neighborhood Hits	455	Target Neighborhood Hits	1437	Shared Neighborhood Hits	134
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

GRAP2_HUMAN
θ value	8.99809 (rank : 427)	NC score	0.135732 (rank : 79)
Query Neighborhood Hits	455	Target Neighborhood Hits	304	Shared Neighborhood Hits	86
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

HAP1_HUMAN
θ value	8.99809 (rank : 428)	NC score	0.061506 (rank : 623)
Query Neighborhood Hits	455	Target Neighborhood Hits	606	Shared Neighborhood Hits	92
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

KMHN1_MOUSE
θ value	8.99809 (rank : 429)	NC score	0.073387 (rank : 395)
Query Neighborhood Hits	455	Target Neighborhood Hits	949	Shared Neighborhood Hits	106
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

LIPA1_HUMAN
θ value	8.99809 (rank : 430)	NC score	0.070510 (rank : 439)
Query Neighborhood Hits	455	Target Neighborhood Hits	1294	Shared Neighborhood Hits	141
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

MNDA_HUMAN
θ value	8.99809 (rank : 431)	NC score	0.014828 (rank : 992)
Query Neighborhood Hits	455	Target Neighborhood Hits	76	Shared Neighborhood Hits	20
SwissProt Accessions	P41218	Gene names	MNDA
Domain Architecture
Description	Myeloid cell nuclear differentiation antigen.

MYH7_HUMAN
θ value	8.99809 (rank : 432)	NC score	0.066132 (rank : 522)
Query Neighborhood Hits	455	Target Neighborhood Hits	1559	Shared Neighborhood Hits	147
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

MYH9_MOUSE
θ value	8.99809 (rank : 433)	NC score	0.084818 (rank : 247)
Query Neighborhood Hits	455	Target Neighborhood Hits	1829	Shared Neighborhood Hits	173
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYLK2_HUMAN
θ value	8.99809 (rank : 434)	NC score	0.025107 (rank : 945)
Query Neighborhood Hits	455	Target Neighborhood Hits	920	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H1R3, Q96I84	Gene names	MYLK2
Domain Architecture
Description	Myosin light chain kinase 2, skeletal/cardiac muscle (EC 2.7.11.18) (MLCK2).

NELFA_HUMAN
θ value	8.99809 (rank : 435)	NC score	0.066073 (rank : 525)
Query Neighborhood Hits	455	Target Neighborhood Hits	161	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H3P2, O95392	Gene names	WHSC2, NELFA
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein).

NPHP1_HUMAN
θ value	8.99809 (rank : 436)	NC score	0.096235 (rank : 184)
Query Neighborhood Hits	455	Target Neighborhood Hits	288	Shared Neighborhood Hits	83
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

NRG2_HUMAN
θ value	8.99809 (rank : 437)	NC score	0.009993 (rank : 1010)
Query Neighborhood Hits	455	Target Neighborhood Hits	419	Shared Neighborhood Hits	21
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

ODP2_HUMAN
θ value	8.99809 (rank : 438)	NC score	0.013355 (rank : 996)
Query Neighborhood Hits	455	Target Neighborhood Hits	59	Shared Neighborhood Hits	14
SwissProt Accessions	P10515, Q16783	Gene names	DLAT, DLTA
Domain Architecture
Description	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.12) (Pyruvate dehydrogenase complex E2 subunit) (PDCE2) (E2) (Dihydrolipoamide S- acetyltransferase component of pyruvate dehydrogenase complex) (PDC- E2) (70 kDa mitochondrial autoantigen of primary biliary cirrhosis) (PBC) (M2 antigen complex 70 kDa subunit).

RARG2_HUMAN
θ value	8.99809 (rank : 439)	NC score	-0.001067 (rank : 1022)
Query Neighborhood Hits	455	Target Neighborhood Hits	109	Shared Neighborhood Hits	3
SwissProt Accessions	P22932, Q15281	Gene names	RARG, NR1B3
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor gamma-2 (RAR-gamma-2).

RHG25_HUMAN
θ value	8.99809 (rank : 440)	NC score	0.035216 (rank : 909)
Query Neighborhood Hits	455	Target Neighborhood Hits	550	Shared Neighborhood Hits	78
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RN168_MOUSE
θ value	8.99809 (rank : 441)	NC score	0.026650 (rank : 935)
Query Neighborhood Hits	455	Target Neighborhood Hits	440	Shared Neighborhood Hits	44
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RUNX1_MOUSE
θ value	8.99809 (rank : 442)	NC score	0.016361 (rank : 987)
Query Neighborhood Hits	455	Target Neighborhood Hits	93	Shared Neighborhood Hits	14
SwissProt Accessions	Q03347, O08598, Q62049, Q9ESB9, Q9ET65	Gene names	Runx1, Aml1, Cbfa2, Pebp2ab
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

SDCG1_MOUSE
θ value	8.99809 (rank : 443)	NC score	0.022087 (rank : 960)
Query Neighborhood Hits	455	Target Neighborhood Hits	168	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CCP0, Q66JX6, Q8C9R6, Q8CA65, Q8JZT9, Q8R072, Q9CW30, Q9CYB8, Q9D4A9	Gene names	Sdccag1
Domain Architecture
Description	Serologically defined colon cancer antigen 1.

SHAN1_HUMAN
θ value	8.99809 (rank : 444)	NC score	0.079873 (rank : 293)
Query Neighborhood Hits	455	Target Neighborhood Hits	1041	Shared Neighborhood Hits	135
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SL9A1_MOUSE
θ value	8.99809 (rank : 445)	NC score	0.005258 (rank : 1020)
Query Neighborhood Hits	455	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q61165	Gene names	Slc9a1, Nhe1
Domain Architecture
Description	Sodium/hydrogen exchanger 1 (Na(+)/H(+) exchanger 1) (NHE-1) (Solute carrier family 9 member 1).

SOX12_HUMAN
θ value	8.99809 (rank : 446)	NC score	0.008508 (rank : 1015)
Query Neighborhood Hits	455	Target Neighborhood Hits	111	Shared Neighborhood Hits	10
SwissProt Accessions	O15370, Q9NUD4	Gene names	SOX12, SOX22
Domain Architecture
Description	SOX-12 protein (SOX-22 protein).

SSH1_HUMAN
θ value	8.99809 (rank : 447)	NC score	0.009755 (rank : 1013)
Query Neighborhood Hits	455	Target Neighborhood Hits	164	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WYL5, Q6P6C0, Q8N9A7, Q8WYL3, Q8WYL4, Q9P2P8	Gene names	SSH1, KIAA1298, SSH1L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (hSSH-1L).

SYT3_MOUSE
θ value	8.99809 (rank : 448)	NC score	0.012273 (rank : 1001)
Query Neighborhood Hits	455	Target Neighborhood Hits	147	Shared Neighborhood Hits	15
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

TAOK2_MOUSE
θ value	8.99809 (rank : 449)	NC score	0.030437 (rank : 918)
Query Neighborhood Hits	455	Target Neighborhood Hits	1373	Shared Neighborhood Hits	112
SwissProt Accessions	Q6ZQ29, Q7TSS8	Gene names	Taok2, Kiaa0881
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2).

TOIP2_HUMAN
θ value	8.99809 (rank : 450)	NC score	0.017025 (rank : 982)
Query Neighborhood Hits	455	Target Neighborhood Hits	102	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NFQ8	Gene names	TOR1AIP2, LULL1
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2 (Lumenal domain-like LAP1).

TSPY1_HUMAN
θ value	8.99809 (rank : 451)	NC score	0.011923 (rank : 1005)
Query Neighborhood Hits	455	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q01534, O00216, P09002, Q9UNN7	Gene names	TSPY1, TSPY
Domain Architecture
Description	Testis-specific Y-encoded protein 1.

UT14A_HUMAN
θ value	8.99809 (rank : 452)	NC score	0.021539 (rank : 965)
Query Neighborhood Hits	455	Target Neighborhood Hits	168	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BVJ6, Q5JYF1	Gene names	UTP14A
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog A (Antigen NY-CO- 16).

VTNC_MOUSE
θ value	8.99809 (rank : 453)	NC score	0.017057 (rank : 981)
Query Neighborhood Hits	455	Target Neighborhood Hits	74	Shared Neighborhood Hits	8
SwissProt Accessions	P29788, Q8VII4	Gene names	Vtn
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein).

ZAN_HUMAN
θ value	8.99809 (rank : 454)	NC score	0.066560 (rank : 510)
Query Neighborhood Hits	455	Target Neighborhood Hits	679	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ZN205_HUMAN
θ value	8.99809 (rank : 455)	NC score	-0.006940 (rank : 1025)
Query Neighborhood Hits	455	Target Neighborhood Hits	743	Shared Neighborhood Hits	16
SwissProt Accessions	O95201	Gene names	ZNF205, ZNF210
Domain Architecture
Description	Zinc finger protein 205 (Zinc finger protein 210).

3BP5_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.054948 (rank : 756)
Query Neighborhood Hits	455	Target Neighborhood Hits	375	Shared Neighborhood Hits	63
SwissProt Accessions	O60239	Gene names	SH3BP5, SAB
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

3BP5_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.051368 (rank : 827)
Query Neighborhood Hits	455	Target Neighborhood Hits	346	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z131, Q8C903, Q8VCZ0	Gene names	Sh3bp5, Sab
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

ABI3_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.177525 (rank : 43)
Query Neighborhood Hits	455	Target Neighborhood Hits	227	Shared Neighborhood Hits	86
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ACINU_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.072898 (rank : 408)
Query Neighborhood Hits	455	Target Neighborhood Hits	828	Shared Neighborhood Hits	129
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ACINU_MOUSE
θ value	θ > 10 (rank : 460)	NC score	0.064963 (rank : 553)
Query Neighborhood Hits	455	Target Neighborhood Hits	712	Shared Neighborhood Hits	115
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ADDB_MOUSE
θ value	θ > 10 (rank : 461)	NC score	0.059743 (rank : 659)
Query Neighborhood Hits	455	Target Neighborhood Hits	574	Shared Neighborhood Hits	105
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

AFF1_HUMAN
θ value	θ > 10 (rank : 462)	NC score	0.055876 (rank : 736)
Query Neighborhood Hits	455	Target Neighborhood Hits	506	Shared Neighborhood Hits	81
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

AKAP2_MOUSE
θ value	θ > 10 (rank : 463)	NC score	0.057120 (rank : 708)
Query Neighborhood Hits	455	Target Neighborhood Hits	385	Shared Neighborhood Hits	87
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

AKAP9_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.084413 (rank : 249)
Query Neighborhood Hits	455	Target Neighborhood Hits	1710	Shared Neighborhood Hits	158
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

ALEX_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.056545 (rank : 723)
Query Neighborhood Hits	455	Target Neighborhood Hits	361	Shared Neighborhood Hits	60
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

AMOL2_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.051774 (rank : 818)
Query Neighborhood Hits	455	Target Neighborhood Hits	603	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Y2J4, Q53EP1, Q96F99, Q9UKB4	Gene names	AMOTL2, KIAA0989
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP).

AMOL2_MOUSE
θ value	θ > 10 (rank : 467)	NC score	0.051409 (rank : 825)
Query Neighborhood Hits	455	Target Neighborhood Hits	591	Shared Neighborhood Hits	82
SwissProt Accessions	Q8K371, Q3TPM1, Q7TPE4, Q8BP84, Q8BS08, Q9QUS0	Gene names	Amotl2
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2.

AN30A_HUMAN
θ value	θ > 10 (rank : 468)	NC score	0.069531 (rank : 450)
Query Neighborhood Hits	455	Target Neighborhood Hits	1119	Shared Neighborhood Hits	139
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ANM2_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.067425 (rank : 492)
Query Neighborhood Hits	455	Target Neighborhood Hits	175	Shared Neighborhood Hits	66
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

ANM2_MOUSE
θ value	θ > 10 (rank : 470)	NC score	0.063387 (rank : 593)
Query Neighborhood Hits	455	Target Neighborhood Hits	175	Shared Neighborhood Hits	65
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

ANR11_HUMAN
θ value	θ > 10 (rank : 471)	NC score	0.052621 (rank : 808)
Query Neighborhood Hits	455	Target Neighborhood Hits	1289	Shared Neighborhood Hits	163
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ANR26_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.066322 (rank : 518)
Query Neighborhood Hits	455	Target Neighborhood Hits	1614	Shared Neighborhood Hits	146
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ANR26_MOUSE
θ value	θ > 10 (rank : 473)	NC score	0.066229 (rank : 519)
Query Neighborhood Hits	455	Target Neighborhood Hits	1554	Shared Neighborhood Hits	135
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ARHG3_HUMAN
θ value	θ > 10 (rank : 474)	NC score	0.054997 (rank : 755)
Query Neighborhood Hits	455	Target Neighborhood Hits	82	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

ARHG3_MOUSE
θ value	θ > 10 (rank : 475)	NC score	0.055322 (rank : 749)
Query Neighborhood Hits	455	Target Neighborhood Hits	85	Shared Neighborhood Hits	16
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

ARHG4_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.093548 (rank : 200)
Query Neighborhood Hits	455	Target Neighborhood Hits	242	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG4_MOUSE
θ value	θ > 10 (rank : 477)	NC score	0.073837 (rank : 387)
Query Neighborhood Hits	455	Target Neighborhood Hits	185	Shared Neighborhood Hits	57
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG7_HUMAN
θ value	θ > 10 (rank : 478)	NC score	0.133492 (rank : 86)
Query Neighborhood Hits	455	Target Neighborhood Hits	347	Shared Neighborhood Hits	94
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

ARHG7_MOUSE
θ value	θ > 10 (rank : 479)	NC score	0.136816 (rank : 76)
Query Neighborhood Hits	455	Target Neighborhood Hits	396	Shared Neighborhood Hits	103
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

ARHG8_HUMAN
θ value	θ > 10 (rank : 480)	NC score	0.050949 (rank : 840)
Query Neighborhood Hits	455	Target Neighborhood Hits	85	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

ARHG8_MOUSE
θ value	θ > 10 (rank : 481)	NC score	0.055429 (rank : 746)
Query Neighborhood Hits	455	Target Neighborhood Hits	79	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

ARHG9_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.092323 (rank : 208)
Query Neighborhood Hits	455	Target Neighborhood Hits	235	Shared Neighborhood Hits	78
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

ARHG9_MOUSE
θ value	θ > 10 (rank : 483)	NC score	0.088657 (rank : 231)
Query Neighborhood Hits	455	Target Neighborhood Hits	234	Shared Neighborhood Hits	76
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

ARHGF_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.097946 (rank : 176)
Query Neighborhood Hits	455	Target Neighborhood Hits	214	Shared Neighborhood Hits	50
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

ATN1_HUMAN
θ value	θ > 10 (rank : 485)	NC score	0.055909 (rank : 735)
Query Neighborhood Hits	455	Target Neighborhood Hits	676	Shared Neighborhood Hits	79
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

AZI1_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.075095 (rank : 368)
Query Neighborhood Hits	455	Target Neighborhood Hits	1000	Shared Neighborhood Hits	115
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

BAG3_MOUSE
θ value	θ > 10 (rank : 487)	NC score	0.067843 (rank : 483)
Query Neighborhood Hits	455	Target Neighborhood Hits	513	Shared Neighborhood Hits	95
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

BAIP2_MOUSE
θ value	θ > 10 (rank : 488)	NC score	0.052392 (rank : 811)
Query Neighborhood Hits	455	Target Neighborhood Hits	185	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BKX1, Q91V97, Q923V9, Q923W0	Gene names	Baiap2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor tyrosine kinase 53 kDa substrate).

BCAR1_HUMAN
θ value	θ > 10 (rank : 489)	NC score	0.109399 (rank : 139)
Query Neighborhood Hits	455	Target Neighborhood Hits	554	Shared Neighborhood Hits	132
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BCAR1_MOUSE
θ value	θ > 10 (rank : 490)	NC score	0.101503 (rank : 163)
Query Neighborhood Hits	455	Target Neighborhood Hits	438	Shared Neighborhood Hits	121
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BI2L1_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.060469 (rank : 641)
Query Neighborhood Hits	455	Target Neighborhood Hits	156	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

BICD1_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.065432 (rank : 542)
Query Neighborhood Hits	455	Target Neighborhood Hits	844	Shared Neighborhood Hits	106
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

BICD1_MOUSE
θ value	θ > 10 (rank : 493)	NC score	0.063434 (rank : 590)
Query Neighborhood Hits	455	Target Neighborhood Hits	837	Shared Neighborhood Hits	101
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

BICD2_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.066596 (rank : 509)
Query Neighborhood Hits	455	Target Neighborhood Hits	856	Shared Neighborhood Hits	102
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BICD2_MOUSE
θ value	θ > 10 (rank : 495)	NC score	0.066616 (rank : 508)
Query Neighborhood Hits	455	Target Neighborhood Hits	864	Shared Neighborhood Hits	103
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BPA1_MOUSE
θ value	θ > 10 (rank : 496)	NC score	0.056272 (rank : 728)
Query Neighborhood Hits	455	Target Neighborhood Hits	1477	Shared Neighborhood Hits	146
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BPAEA_HUMAN
θ value	θ > 10 (rank : 497)	NC score	0.055625 (rank : 742)
Query Neighborhood Hits	455	Target Neighborhood Hits	1369	Shared Neighborhood Hits	132
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BPAEA_MOUSE
θ value	θ > 10 (rank : 498)	NC score	0.068113 (rank : 478)
Query Neighborhood Hits	455	Target Neighborhood Hits	1480	Shared Neighborhood Hits	139
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BRD4_HUMAN
θ value	θ > 10 (rank : 499)	NC score	0.059159 (rank : 669)
Query Neighborhood Hits	455	Target Neighborhood Hits	851	Shared Neighborhood Hits	123
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

BRD8_MOUSE
θ value	θ > 10 (rank : 500)	NC score	0.051499 (rank : 824)
Query Neighborhood Hits	455	Target Neighborhood Hits	422	Shared Neighborhood Hits	75
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

BRE1A_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.061355 (rank : 628)
Query Neighborhood Hits	455	Target Neighborhood Hits	1071	Shared Neighborhood Hits	112
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
θ value	θ > 10 (rank : 502)	NC score	0.059424 (rank : 664)
Query Neighborhood Hits	455	Target Neighborhood Hits	1025	Shared Neighborhood Hits	104
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

BRE1B_MOUSE
θ value	θ > 10 (rank : 503)	NC score	0.067006 (rank : 498)
Query Neighborhood Hits	455	Target Neighborhood Hits	970	Shared Neighborhood Hits	102
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

BSN_HUMAN
θ value	θ > 10 (rank : 504)	NC score	0.099016 (rank : 174)
Query Neighborhood Hits	455	Target Neighborhood Hits	1537	Shared Neighborhood Hits	188
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

C102B_HUMAN
θ value	θ > 10 (rank : 505)	NC score	0.063540 (rank : 587)
Query Neighborhood Hits	455	Target Neighborhood Hits	542	Shared Neighborhood Hits	80
SwissProt Accessions	Q68D86, Q7Z467, Q8NDK7, Q9H5C1	Gene names	CCDC102B, C18orf14
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 102B.

CABIN_HUMAN
θ value	θ > 10 (rank : 506)	NC score	0.072277 (rank : 414)
Query Neighborhood Hits	455	Target Neighborhood Hits	490	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CAF1A_HUMAN
θ value	θ > 10 (rank : 507)	NC score	0.054165 (rank : 770)
Query Neighborhood Hits	455	Target Neighborhood Hits	750	Shared Neighborhood Hits	87
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CAF1A_MOUSE
θ value	θ > 10 (rank : 508)	NC score	0.058367 (rank : 682)
Query Neighborhood Hits	455	Target Neighborhood Hits	736	Shared Neighborhood Hits	91
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CALD1_HUMAN
θ value	θ > 10 (rank : 509)	NC score	0.068202 (rank : 475)
Query Neighborhood Hits	455	Target Neighborhood Hits	959	Shared Neighborhood Hits	104
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

CAR10_HUMAN
θ value	θ > 10 (rank : 510)	NC score	0.055653 (rank : 741)
Query Neighborhood Hits	455	Target Neighborhood Hits	569	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

CAR11_HUMAN
θ value	θ > 10 (rank : 511)	NC score	0.058619 (rank : 678)
Query Neighborhood Hits	455	Target Neighborhood Hits	690	Shared Neighborhood Hits	91
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

CARD9_HUMAN
θ value	θ > 10 (rank : 512)	NC score	0.066078 (rank : 524)
Query Neighborhood Hits	455	Target Neighborhood Hits	602	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

CASL_HUMAN
θ value	θ > 10 (rank : 513)	NC score	0.076792 (rank : 341)
Query Neighborhood Hits	455	Target Neighborhood Hits	259	Shared Neighborhood Hits	81
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

CASL_MOUSE
θ value	θ > 10 (rank : 514)	NC score	0.076840 (rank : 339)
Query Neighborhood Hits	455	Target Neighborhood Hits	225	Shared Neighborhood Hits	81
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

CASP_HUMAN
θ value	θ > 10 (rank : 515)	NC score	0.077606 (rank : 327)
Query Neighborhood Hits	455	Target Neighborhood Hits	1131	Shared Neighborhood Hits	135
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CASP_MOUSE
θ value	θ > 10 (rank : 516)	NC score	0.078989 (rank : 307)
Query Neighborhood Hits	455	Target Neighborhood Hits	1152	Shared Neighborhood Hits	132
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CBP_MOUSE
θ value	θ > 10 (rank : 517)	NC score	0.075026 (rank : 371)
Query Neighborhood Hits	455	Target Neighborhood Hits	1051	Shared Neighborhood Hits	139
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CCD11_HUMAN
θ value	θ > 10 (rank : 518)	NC score	0.076954 (rank : 335)
Query Neighborhood Hits	455	Target Neighborhood Hits	822	Shared Neighborhood Hits	102
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CCD13_HUMAN
θ value	θ > 10 (rank : 519)	NC score	0.066556 (rank : 511)
Query Neighborhood Hits	455	Target Neighborhood Hits	721	Shared Neighborhood Hits	95
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

CCD19_HUMAN
θ value	θ > 10 (rank : 520)	NC score	0.067031 (rank : 497)
Query Neighborhood Hits	455	Target Neighborhood Hits	639	Shared Neighborhood Hits	91
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

CCD21_HUMAN
θ value	θ > 10 (rank : 521)	NC score	0.084145 (rank : 250)
Query Neighborhood Hits	455	Target Neighborhood Hits	1228	Shared Neighborhood Hits	141
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CCD27_HUMAN
θ value	θ > 10 (rank : 522)	NC score	0.061416 (rank : 625)
Query Neighborhood Hits	455	Target Neighborhood Hits	594	Shared Neighborhood Hits	83
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

CCD27_MOUSE
θ value	θ > 10 (rank : 523)	NC score	0.057127 (rank : 707)
Query Neighborhood Hits	455	Target Neighborhood Hits	461	Shared Neighborhood Hits	78
SwissProt Accessions	Q3V036	Gene names	Ccdc27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

CCD39_HUMAN
θ value	θ > 10 (rank : 524)	NC score	0.072197 (rank : 416)
Query Neighborhood Hits	455	Target Neighborhood Hits	868	Shared Neighborhood Hits	107
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD39_MOUSE
θ value	θ > 10 (rank : 525)	NC score	0.076144 (rank : 355)
Query Neighborhood Hits	455	Target Neighborhood Hits	1026	Shared Neighborhood Hits	122
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD41_HUMAN
θ value	θ > 10 (rank : 526)	NC score	0.072910 (rank : 406)
Query Neighborhood Hits	455	Target Neighborhood Hits	1139	Shared Neighborhood Hits	121
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

CCD41_MOUSE
θ value	θ > 10 (rank : 527)	NC score	0.076432 (rank : 351)
Query Neighborhood Hits	455	Target Neighborhood Hits	1399	Shared Neighborhood Hits	137
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CCD42_HUMAN
θ value	θ > 10 (rank : 528)	NC score	0.057192 (rank : 705)
Query Neighborhood Hits	455	Target Neighborhood Hits	406	Shared Neighborhood Hits	68
SwissProt Accessions	Q96M95, Q8N6Q0	Gene names	CCDC42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

CCD45_HUMAN
θ value	θ > 10 (rank : 529)	NC score	0.056386 (rank : 726)
Query Neighborhood Hits	455	Target Neighborhood Hits	525	Shared Neighborhood Hits	81
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CCD45_MOUSE
θ value	θ > 10 (rank : 530)	NC score	0.062222 (rank : 607)
Query Neighborhood Hits	455	Target Neighborhood Hits	663	Shared Neighborhood Hits	96
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CCD46_HUMAN
θ value	θ > 10 (rank : 531)	NC score	0.079934 (rank : 290)
Query Neighborhood Hits	455	Target Neighborhood Hits	1430	Shared Neighborhood Hits	144
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CCD62_HUMAN
θ value	θ > 10 (rank : 532)	NC score	0.064701 (rank : 555)
Query Neighborhood Hits	455	Target Neighborhood Hits	631	Shared Neighborhood Hits	94
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

CCD91_HUMAN
θ value	θ > 10 (rank : 533)	NC score	0.068406 (rank : 469)
Query Neighborhood Hits	455	Target Neighborhood Hits	868	Shared Neighborhood Hits	113
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

CCD91_MOUSE
θ value	θ > 10 (rank : 534)	NC score	0.060402 (rank : 643)
Query Neighborhood Hits	455	Target Neighborhood Hits	699	Shared Neighborhood Hits	88
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

CCD93_HUMAN
θ value	θ > 10 (rank : 535)	NC score	0.064045 (rank : 576)
Query Neighborhood Hits	455	Target Neighborhood Hits	600	Shared Neighborhood Hits	85
SwissProt Accessions	Q567U6, Q4LE78, Q53TJ2, Q8TBX5, Q9H6R5, Q9NV15	Gene names	CCDC93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

CCD96_HUMAN
θ value	θ > 10 (rank : 536)	NC score	0.080146 (rank : 288)
Query Neighborhood Hits	455	Target Neighborhood Hits	595	Shared Neighborhood Hits	103
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CCD96_MOUSE
θ value	θ > 10 (rank : 537)	NC score	0.074531 (rank : 379)
Query Neighborhood Hits	455	Target Neighborhood Hits	704	Shared Neighborhood Hits	106
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CCDC6_HUMAN
θ value	θ > 10 (rank : 538)	NC score	0.065294 (rank : 544)
Query Neighborhood Hits	455	Target Neighborhood Hits	723	Shared Neighborhood Hits	103
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

CCHCR_HUMAN
θ value	θ > 10 (rank : 539)	NC score	0.057374 (rank : 702)
Query Neighborhood Hits	455	Target Neighborhood Hits	717	Shared Neighborhood Hits	89
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

CCHCR_MOUSE
θ value	θ > 10 (rank : 540)	NC score	0.068953 (rank : 463)
Query Neighborhood Hits	455	Target Neighborhood Hits	932	Shared Neighborhood Hits	110
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

CDN1C_HUMAN
θ value	θ > 10 (rank : 541)	NC score	0.078595 (rank : 315)
Query Neighborhood Hits	455	Target Neighborhood Hits	168	Shared Neighborhood Hits	42
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CDR2_HUMAN
θ value	θ > 10 (rank : 542)	NC score	0.053439 (rank : 789)
Query Neighborhood Hits	455	Target Neighborhood Hits	404	Shared Neighborhood Hits	77
SwissProt Accessions	Q01850, Q13977	Gene names	CDR2, PCD17
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related protein 2 (Paraneoplastic cerebellar degeneration-associated antigen) (Major Yo paraneoplastic antigen).

CDR2_MOUSE
θ value	θ > 10 (rank : 543)	NC score	0.063614 (rank : 585)
Query Neighborhood Hits	455	Target Neighborhood Hits	482	Shared Neighborhood Hits	81
SwissProt Accessions	P97817	Gene names	Cdr2
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related protein 2.

CE152_HUMAN
θ value	θ > 10 (rank : 544)	NC score	0.070963 (rank : 431)
Query Neighborhood Hits	455	Target Neighborhood Hits	976	Shared Neighborhood Hits	112
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

CE290_HUMAN
θ value	θ > 10 (rank : 545)	NC score	0.074968 (rank : 372)
Query Neighborhood Hits	455	Target Neighborhood Hits	1553	Shared Neighborhood Hits	140
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CENPF_HUMAN
θ value	θ > 10 (rank : 546)	NC score	0.081009 (rank : 278)
Query Neighborhood Hits	455	Target Neighborhood Hits	1932	Shared Neighborhood Hits	164
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CENPJ_HUMAN
θ value	θ > 10 (rank : 547)	NC score	0.058221 (rank : 684)
Query Neighborhood Hits	455	Target Neighborhood Hits	721	Shared Neighborhood Hits	100
SwissProt Accessions	Q9HC77, Q5T6R5, Q96KS5, Q9C067	Gene names	CENPJ, CPAP, LAP, LIP1
Domain Architecture	No domain graphic available
Description	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1).

CEP35_HUMAN
θ value	θ > 10 (rank : 548)	NC score	0.056766 (rank : 715)
Query Neighborhood Hits	455	Target Neighborhood Hits	811	Shared Neighborhood Hits	120
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

CEP55_HUMAN
θ value	θ > 10 (rank : 549)	NC score	0.054604 (rank : 765)
Query Neighborhood Hits	455	Target Neighborhood Hits	504	Shared Neighborhood Hits	73
SwissProt Accessions	Q53EZ4, Q32WF5, Q3MV20, Q5VY28, Q6N034, Q96H32, Q9NVS7	Gene names	CEP55, C10orf3, URCC6
Domain Architecture	No domain graphic available
Description	Centrosome protein 55 (Up-regulated in colon cancer 6).

CEP55_MOUSE
θ value	θ > 10 (rank : 550)	NC score	0.064291 (rank : 568)
Query Neighborhood Hits	455	Target Neighborhood Hits	693	Shared Neighborhood Hits	95
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

CEP57_MOUSE
θ value	θ > 10 (rank : 551)	NC score	0.050104 (rank : 857)
Query Neighborhood Hits	455	Target Neighborhood Hits	580	Shared Neighborhood Hits	81
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

CEP63_HUMAN
θ value	θ > 10 (rank : 552)	NC score	0.074825 (rank : 376)
Query Neighborhood Hits	455	Target Neighborhood Hits	1005	Shared Neighborhood Hits	122
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

CEP70_HUMAN
θ value	θ > 10 (rank : 553)	NC score	0.050781 (rank : 844)
Query Neighborhood Hits	455	Target Neighborhood Hits	432	Shared Neighborhood Hits	68
SwissProt Accessions	Q8NHQ1, Q96B31, Q9H2C3, Q9H2Z1, Q9H940	Gene names	CEP70, BITE
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein) (p10-binding protein).

CEP70_MOUSE
θ value	θ > 10 (rank : 554)	NC score	0.052374 (rank : 812)
Query Neighborhood Hits	455	Target Neighborhood Hits	532	Shared Neighborhood Hits	74
SwissProt Accessions	Q6IQY5, Q9CRL9, Q9CTS4, Q9JIC1	Gene names	Cep70
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein).

CF060_HUMAN
θ value	θ > 10 (rank : 555)	NC score	0.076162 (rank : 354)
Query Neighborhood Hits	455	Target Neighborhood Hits	1270	Shared Neighborhood Hits	131
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

CF152_HUMAN
θ value	θ > 10 (rank : 556)	NC score	0.068984 (rank : 461)
Query Neighborhood Hits	455	Target Neighborhood Hits	704	Shared Neighborhood Hits	91
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

CF152_MOUSE
θ value	θ > 10 (rank : 557)	NC score	0.057178 (rank : 706)
Query Neighborhood Hits	455	Target Neighborhood Hits	597	Shared Neighborhood Hits	86
SwissProt Accessions	Q80ST9, Q9CYM9, Q9D5J9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf152 homolog.

CGRE1_HUMAN
θ value	θ > 10 (rank : 558)	NC score	0.053665 (rank : 785)
Query Neighborhood Hits	455	Target Neighborhood Hits	354	Shared Neighborhood Hits	54
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

CI039_HUMAN
θ value	θ > 10 (rank : 559)	NC score	0.082396 (rank : 262)
Query Neighborhood Hits	455	Target Neighborhood Hits	1171	Shared Neighborhood Hits	130
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CI093_HUMAN
θ value	θ > 10 (rank : 560)	NC score	0.086362 (rank : 240)
Query Neighborhood Hits	455	Target Neighborhood Hits	1088	Shared Neighborhood Hits	127
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CIC_MOUSE
θ value	θ > 10 (rank : 561)	NC score	0.057207 (rank : 704)
Query Neighborhood Hits	455	Target Neighborhood Hits	742	Shared Neighborhood Hits	103
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CING_MOUSE
θ value	θ > 10 (rank : 562)	NC score	0.076735 (rank : 343)
Query Neighborhood Hits	455	Target Neighborhood Hits	1432	Shared Neighborhood Hits	135
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CIP4_HUMAN
θ value	θ > 10 (rank : 563)	NC score	0.062618 (rank : 603)
Query Neighborhood Hits	455	Target Neighborhood Hits	374	Shared Neighborhood Hits	85
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

CJ012_HUMAN
θ value	θ > 10 (rank : 564)	NC score	0.064140 (rank : 572)
Query Neighborhood Hits	455	Target Neighborhood Hits	467	Shared Neighborhood Hits	82
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

CJ068_HUMAN
θ value	θ > 10 (rank : 565)	NC score	0.059138 (rank : 670)
Query Neighborhood Hits	455	Target Neighborhood Hits	316	Shared Neighborhood Hits	58
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

CJ078_MOUSE
θ value	θ > 10 (rank : 566)	NC score	0.079770 (rank : 296)
Query Neighborhood Hits	455	Target Neighborhood Hits	559	Shared Neighborhood Hits	89
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CJ118_HUMAN
θ value	θ > 10 (rank : 567)	NC score	0.066466 (rank : 515)
Query Neighborhood Hits	455	Target Neighborhood Hits	937	Shared Neighborhood Hits	108
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

CJ118_MOUSE
θ value	θ > 10 (rank : 568)	NC score	0.071554 (rank : 426)
Query Neighborhood Hits	455	Target Neighborhood Hits	1132	Shared Neighborhood Hits	117
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

CK024_HUMAN
θ value	θ > 10 (rank : 569)	NC score	0.093851 (rank : 198)
Query Neighborhood Hits	455	Target Neighborhood Hits	408	Shared Neighborhood Hits	85
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CK024_MOUSE
θ value	θ > 10 (rank : 570)	NC score	0.060595 (rank : 638)
Query Neighborhood Hits	455	Target Neighborhood Hits	307	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

CK5P2_HUMAN
θ value	θ > 10 (rank : 571)	NC score	0.078753 (rank : 312)
Query Neighborhood Hits	455	Target Neighborhood Hits	1433	Shared Neighborhood Hits	160
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CKAP4_HUMAN
θ value	θ > 10 (rank : 572)	NC score	0.061862 (rank : 611)
Query Neighborhood Hits	455	Target Neighborhood Hits	592	Shared Neighborhood Hits	88
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CKAP4_MOUSE
θ value	θ > 10 (rank : 573)	NC score	0.054750 (rank : 762)
Query Neighborhood Hits	455	Target Neighborhood Hits	596	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CLIC6_HUMAN
θ value	θ > 10 (rank : 574)	NC score	0.056727 (rank : 717)
Query Neighborhood Hits	455	Target Neighborhood Hits	289	Shared Neighborhood Hits	47
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

CN032_MOUSE
θ value	θ > 10 (rank : 575)	NC score	0.054101 (rank : 772)
Query Neighborhood Hits	455	Target Neighborhood Hits	233	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CN145_HUMAN
θ value	θ > 10 (rank : 576)	NC score	0.073407 (rank : 394)
Query Neighborhood Hits	455	Target Neighborhood Hits	1196	Shared Neighborhood Hits	125
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

CN145_MOUSE
θ value	θ > 10 (rank : 577)	NC score	0.064466 (rank : 563)
Query Neighborhood Hits	455	Target Neighborhood Hits	916	Shared Neighborhood Hits	97
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

CNOT3_HUMAN
θ value	θ > 10 (rank : 578)	NC score	0.059455 (rank : 663)
Query Neighborhood Hits	455	Target Neighborhood Hits	425	Shared Neighborhood Hits	74
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CNOT3_MOUSE
θ value	θ > 10 (rank : 579)	NC score	0.052627 (rank : 807)
Query Neighborhood Hits	455	Target Neighborhood Hits	504	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CNTRB_HUMAN
θ value	θ > 10 (rank : 580)	NC score	0.057995 (rank : 687)
Query Neighborhood Hits	455	Target Neighborhood Hits	690	Shared Neighborhood Hits	89
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CNTRB_MOUSE
θ value	θ > 10 (rank : 581)	NC score	0.079758 (rank : 297)
Query Neighborhood Hits	455	Target Neighborhood Hits	1029	Shared Neighborhood Hits	143
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CO002_HUMAN
θ value	θ > 10 (rank : 582)	NC score	0.060871 (rank : 632)
Query Neighborhood Hits	455	Target Neighborhood Hits	387	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

CO039_HUMAN
θ value	θ > 10 (rank : 583)	NC score	0.054674 (rank : 764)
Query Neighborhood Hits	455	Target Neighborhood Hits	264	Shared Neighborhood Hits	60
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

CO039_MOUSE
θ value	θ > 10 (rank : 584)	NC score	0.063575 (rank : 586)
Query Neighborhood Hits	455	Target Neighborhood Hits	445	Shared Neighborhood Hits	83
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

CP135_HUMAN
θ value	θ > 10 (rank : 585)	NC score	0.078198 (rank : 321)
Query Neighborhood Hits	455	Target Neighborhood Hits	1290	Shared Neighborhood Hits	128
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CP135_MOUSE
θ value	θ > 10 (rank : 586)	NC score	0.080721 (rank : 283)
Query Neighborhood Hits	455	Target Neighborhood Hits	1278	Shared Neighborhood Hits	132
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CP250_HUMAN
θ value	θ > 10 (rank : 587)	NC score	0.080156 (rank : 287)
Query Neighborhood Hits	455	Target Neighborhood Hits	1805	Shared Neighborhood Hits	164
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CP250_MOUSE
θ value	θ > 10 (rank : 588)	NC score	0.074354 (rank : 382)
Query Neighborhood Hits	455	Target Neighborhood Hits	1583	Shared Neighborhood Hits	154
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

CR034_HUMAN
θ value	θ > 10 (rank : 589)	NC score	0.060460 (rank : 642)
Query Neighborhood Hits	455	Target Neighborhood Hits	538	Shared Neighborhood Hits	84
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

CR034_MOUSE
θ value	θ > 10 (rank : 590)	NC score	0.055039 (rank : 754)
Query Neighborhood Hits	455	Target Neighborhood Hits	643	Shared Neighborhood Hits	80
SwissProt Accessions	Q8CDV0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34 homolog.

CRCM_HUMAN
θ value	θ > 10 (rank : 591)	NC score	0.053382 (rank : 793)
Query Neighborhood Hits	455	Target Neighborhood Hits	520	Shared Neighborhood Hits	74
SwissProt Accessions	P23508	Gene names	MCC
Domain Architecture
Description	Colorectal mutant cancer protein (Protein MCC).

CRKL_MOUSE
θ value	θ > 10 (rank : 592)	NC score	0.099643 (rank : 169)
Query Neighborhood Hits	455	Target Neighborhood Hits	307	Shared Neighborhood Hits	78
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

CRK_HUMAN
θ value	θ > 10 (rank : 593)	NC score	0.094127 (rank : 196)
Query Neighborhood Hits	455	Target Neighborhood Hits	308	Shared Neighborhood Hits	78
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
θ value	θ > 10 (rank : 594)	NC score	0.096304 (rank : 183)
Query Neighborhood Hits	455	Target Neighborhood Hits	314	Shared Neighborhood Hits	79
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CROCC_HUMAN
θ value	θ > 10 (rank : 595)	NC score	0.068323 (rank : 473)
Query Neighborhood Hits	455	Target Neighborhood Hits	1409	Shared Neighborhood Hits	142
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CROCC_MOUSE
θ value	θ > 10 (rank : 596)	NC score	0.073239 (rank : 400)
Query Neighborhood Hits	455	Target Neighborhood Hits	1460	Shared Neighborhood Hits	146
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CSKI1_HUMAN
θ value	θ > 10 (rank : 597)	NC score	0.051811 (rank : 817)
Query Neighborhood Hits	455	Target Neighborhood Hits	997	Shared Neighborhood Hits	122
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CT032_HUMAN
θ value	θ > 10 (rank : 598)	NC score	0.100261 (rank : 167)
Query Neighborhood Hits	455	Target Neighborhood Hits	235	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

CT096_HUMAN
θ value	θ > 10 (rank : 599)	NC score	0.050707 (rank : 848)
Query Neighborhood Hits	455	Target Neighborhood Hits	438	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NUD7, Q8N840, Q8NAX5	Gene names	C20orf96
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf96.

CT151_HUMAN
θ value	θ > 10 (rank : 600)	NC score	0.054148 (rank : 771)
Query Neighborhood Hits	455	Target Neighborhood Hits	382	Shared Neighborhood Hits	76
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

CT2NL_HUMAN
θ value	θ > 10 (rank : 601)	NC score	0.071946 (rank : 420)
Query Neighborhood Hits	455	Target Neighborhood Hits	1059	Shared Neighborhood Hits	129
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CTGE5_HUMAN
θ value	θ > 10 (rank : 602)	NC score	0.051532 (rank : 823)
Query Neighborhood Hits	455	Target Neighborhood Hits	800	Shared Neighborhood Hits	100
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

CTGE5_MOUSE
θ value	θ > 10 (rank : 603)	NC score	0.061217 (rank : 629)
Query Neighborhood Hits	455	Target Neighborhood Hits	928	Shared Neighborhood Hits	116
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

CUTL1_MOUSE
θ value	θ > 10 (rank : 604)	NC score	0.088560 (rank : 232)
Query Neighborhood Hits	455	Target Neighborhood Hits	1620	Shared Neighborhood Hits	195
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

CYLN2_HUMAN
θ value	θ > 10 (rank : 605)	NC score	0.072496 (rank : 412)
Query Neighborhood Hits	455	Target Neighborhood Hits	1004	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

CYLN2_MOUSE
θ value	θ > 10 (rank : 606)	NC score	0.069302 (rank : 457)
Query Neighborhood Hits	455	Target Neighborhood Hits	1002	Shared Neighborhood Hits	115
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

CYTSA_HUMAN
θ value	θ > 10 (rank : 607)	NC score	0.070115 (rank : 443)
Query Neighborhood Hits	455	Target Neighborhood Hits	1138	Shared Neighborhood Hits	146
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

CYTSA_MOUSE
θ value	θ > 10 (rank : 608)	NC score	0.066997 (rank : 499)
Query Neighborhood Hits	455	Target Neighborhood Hits	1104	Shared Neighborhood Hits	132
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

DBNL_HUMAN
θ value	θ > 10 (rank : 609)	NC score	0.131690 (rank : 87)
Query Neighborhood Hits	455	Target Neighborhood Hits	244	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

DBNL_MOUSE
θ value	θ > 10 (rank : 610)	NC score	0.129309 (rank : 96)
Query Neighborhood Hits	455	Target Neighborhood Hits	306	Shared Neighborhood Hits	88
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

DESP_HUMAN
θ value	θ > 10 (rank : 611)	NC score	0.076524 (rank : 348)
Query Neighborhood Hits	455	Target Neighborhood Hits	1470	Shared Neighborhood Hits	144
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

DIAP1_HUMAN
θ value	θ > 10 (rank : 612)	NC score	0.062430 (rank : 605)
Query Neighborhood Hits	455	Target Neighborhood Hits	784	Shared Neighborhood Hits	113
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

DIAP1_MOUSE
θ value	θ > 10 (rank : 613)	NC score	0.061708 (rank : 615)
Query Neighborhood Hits	455	Target Neighborhood Hits	839	Shared Neighborhood Hits	117
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

DIDO1_HUMAN
θ value	θ > 10 (rank : 614)	NC score	0.050898 (rank : 841)
Query Neighborhood Hits	455	Target Neighborhood Hits	960	Shared Neighborhood Hits	120
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

DLG5_HUMAN
θ value	θ > 10 (rank : 615)	NC score	0.061525 (rank : 622)
Query Neighborhood Hits	455	Target Neighborhood Hits	1088	Shared Neighborhood Hits	143
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

DMD_MOUSE
θ value	θ > 10 (rank : 616)	NC score	0.066070 (rank : 526)
Query Neighborhood Hits	455	Target Neighborhood Hits	1111	Shared Neighborhood Hits	117
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

DOCK1_HUMAN
θ value	θ > 10 (rank : 617)	NC score	0.057906 (rank : 692)
Query Neighborhood Hits	455	Target Neighborhood Hits	191	Shared Neighborhood Hits	64
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

DOT1L_HUMAN
θ value	θ > 10 (rank : 618)	NC score	0.055653 (rank : 740)
Query Neighborhood Hits	455	Target Neighborhood Hits	660	Shared Neighborhood Hits	95
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

DREB_MOUSE
θ value	θ > 10 (rank : 619)	NC score	0.057111 (rank : 709)
Query Neighborhood Hits	455	Target Neighborhood Hits	446	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

DYNA_MOUSE
θ value	θ > 10 (rank : 620)	NC score	0.079819 (rank : 294)
Query Neighborhood Hits	455	Target Neighborhood Hits	1084	Shared Neighborhood Hits	124
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

EEA1_HUMAN
θ value	θ > 10 (rank : 621)	NC score	0.076465 (rank : 349)
Query Neighborhood Hits	455	Target Neighborhood Hits	1796	Shared Neighborhood Hits	158
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

EFS_HUMAN
θ value	θ > 10 (rank : 622)	NC score	0.104573 (rank : 152)
Query Neighborhood Hits	455	Target Neighborhood Hits	348	Shared Neighborhood Hits	104
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

EFS_MOUSE
θ value	θ > 10 (rank : 623)	NC score	0.108934 (rank : 140)
Query Neighborhood Hits	455	Target Neighborhood Hits	389	Shared Neighborhood Hits	115
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

ENAH_HUMAN
θ value	θ > 10 (rank : 624)	NC score	0.071886 (rank : 421)
Query Neighborhood Hits	455	Target Neighborhood Hits	784	Shared Neighborhood Hits	118
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

EP15R_HUMAN
θ value	θ > 10 (rank : 625)	NC score	0.075399 (rank : 365)
Query Neighborhood Hits	455	Target Neighborhood Hits	1083	Shared Neighborhood Hits	127
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

EP15R_MOUSE
θ value	θ > 10 (rank : 626)	NC score	0.075684 (rank : 364)
Query Neighborhood Hits	455	Target Neighborhood Hits	1135	Shared Neighborhood Hits	132
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

EP15_HUMAN
θ value	θ > 10 (rank : 627)	NC score	0.069896 (rank : 444)
Query Neighborhood Hits	455	Target Neighborhood Hits	1021	Shared Neighborhood Hits	121
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

EP15_MOUSE
θ value	θ > 10 (rank : 628)	NC score	0.063684 (rank : 584)
Query Neighborhood Hits	455	Target Neighborhood Hits	820	Shared Neighborhood Hits	93
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

ERC2_HUMAN
θ value	θ > 10 (rank : 629)	NC score	0.069324 (rank : 456)
Query Neighborhood Hits	455	Target Neighborhood Hits	1156	Shared Neighborhood Hits	125
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

ERC2_MOUSE
θ value	θ > 10 (rank : 630)	NC score	0.068376 (rank : 472)
Query Neighborhood Hits	455	Target Neighborhood Hits	1166	Shared Neighborhood Hits	123
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

ES8L1_HUMAN
θ value	θ > 10 (rank : 631)	NC score	0.051285 (rank : 828)
Query Neighborhood Hits	455	Target Neighborhood Hits	162	Shared Neighborhood Hits	53
SwissProt Accessions	Q8TE68, Q71RE2, Q8NC10, Q96BB7, Q9BSQ2, Q9GZQ2, Q9NXH0	Gene names	EPS8L1, DRC3, EPS8R1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

ES8L2_HUMAN
θ value	θ > 10 (rank : 632)	NC score	0.054536 (rank : 766)
Query Neighborhood Hits	455	Target Neighborhood Hits	193	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H6S3, Q53GM8, Q8WYW7, Q96K06, Q9H6K9	Gene names	EPS8L2, EPS8R2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

ES8L2_MOUSE
θ value	θ > 10 (rank : 633)	NC score	0.056174 (rank : 730)
Query Neighborhood Hits	455	Target Neighborhood Hits	169	Shared Neighborhood Hits	59
SwissProt Accessions	Q99K30, Q91VT7	Gene names	Eps8l2, Eps8r2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

ES8L3_HUMAN
θ value	θ > 10 (rank : 634)	NC score	0.069392 (rank : 454)
Query Neighborhood Hits	455	Target Neighborhood Hits	206	Shared Neighborhood Hits	61
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

EVPL_HUMAN
θ value	θ > 10 (rank : 635)	NC score	0.058835 (rank : 674)
Query Neighborhood Hits	455	Target Neighborhood Hits	895	Shared Neighborhood Hits	105
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

EVPL_MOUSE
θ value	θ > 10 (rank : 636)	NC score	0.059765 (rank : 658)
Query Neighborhood Hits	455	Target Neighborhood Hits	952	Shared Neighborhood Hits	114
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

FA47A_HUMAN
θ value	θ > 10 (rank : 637)	NC score	0.066637 (rank : 507)
Query Neighborhood Hits	455	Target Neighborhood Hits	451	Shared Neighborhood Hits	74
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

FA47B_HUMAN
θ value	θ > 10 (rank : 638)	NC score	0.064625 (rank : 559)
Query Neighborhood Hits	455	Target Neighborhood Hits	431	Shared Neighborhood Hits	72
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

FLIP1_HUMAN
θ value	θ > 10 (rank : 639)	NC score	0.080748 (rank : 282)
Query Neighborhood Hits	455	Target Neighborhood Hits	1405	Shared Neighborhood Hits	150
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

FLIP1_MOUSE
θ value	θ > 10 (rank : 640)	NC score	0.078825 (rank : 310)
Query Neighborhood Hits	455	Target Neighborhood Hits	1176	Shared Neighborhood Hits	143
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

FMN2_HUMAN
θ value	θ > 10 (rank : 641)	NC score	0.065966 (rank : 529)
Query Neighborhood Hits	455	Target Neighborhood Hits	484	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

FNBP2_HUMAN
θ value	θ > 10 (rank : 642)	NC score	0.058240 (rank : 683)
Query Neighborhood Hits	455	Target Neighborhood Hits	432	Shared Neighborhood Hits	109
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

FYCO1_MOUSE
θ value	θ > 10 (rank : 643)	NC score	0.064195 (rank : 569)
Query Neighborhood Hits	455	Target Neighborhood Hits	1059	Shared Neighborhood Hits	114
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

GAS8_HUMAN
θ value	θ > 10 (rank : 644)	NC score	0.075076 (rank : 369)
Query Neighborhood Hits	455	Target Neighborhood Hits	819	Shared Neighborhood Hits	103
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

GAS8_MOUSE
θ value	θ > 10 (rank : 645)	NC score	0.068398 (rank : 470)
Query Neighborhood Hits	455	Target Neighborhood Hits	622	Shared Neighborhood Hits	88
SwissProt Accessions	Q60779, Q99L71	Gene names	Gas8, Gas11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

GCC1_HUMAN
θ value	θ > 10 (rank : 646)	NC score	0.062840 (rank : 601)
Query Neighborhood Hits	455	Target Neighborhood Hits	887	Shared Neighborhood Hits	107
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GCC1_MOUSE
θ value	θ > 10 (rank : 647)	NC score	0.060161 (rank : 652)
Query Neighborhood Hits	455	Target Neighborhood Hits	777	Shared Neighborhood Hits	95
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GCC2_HUMAN
θ value	θ > 10 (rank : 648)	NC score	0.076796 (rank : 340)
Query Neighborhood Hits	455	Target Neighborhood Hits	1558	Shared Neighborhood Hits	151
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

GCC2_MOUSE
θ value	θ > 10 (rank : 649)	NC score	0.079696 (rank : 301)
Query Neighborhood Hits	455	Target Neighborhood Hits	1619	Shared Neighborhood Hits	153
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

GFAP_HUMAN
θ value	θ > 10 (rank : 650)	NC score	0.053763 (rank : 782)
Query Neighborhood Hits	455	Target Neighborhood Hits	723	Shared Neighborhood Hits	95
SwissProt Accessions	P14136, Q53H98, Q5D055, Q6ZQS3, Q7Z5J6, Q7Z5J7, Q96KS4, Q96P18, Q9UFD0	Gene names	GFAP
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

GFAP_MOUSE
θ value	θ > 10 (rank : 651)	NC score	0.052749 (rank : 805)
Query Neighborhood Hits	455	Target Neighborhood Hits	725	Shared Neighborhood Hits	100
SwissProt Accessions	P03995, Q7TQ30, Q925K3	Gene names	Gfap
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

GGN_HUMAN
θ value	θ > 10 (rank : 652)	NC score	0.061613 (rank : 617)
Query Neighborhood Hits	455	Target Neighborhood Hits	269	Shared Neighborhood Hits	52
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GGN_MOUSE
θ value	θ > 10 (rank : 653)	NC score	0.060026 (rank : 656)
Query Neighborhood Hits	455	Target Neighborhood Hits	311	Shared Neighborhood Hits	52
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GOG8A_HUMAN
θ value	θ > 10 (rank : 654)	NC score	0.060683 (rank : 637)
Query Neighborhood Hits	455	Target Neighborhood Hits	635	Shared Neighborhood Hits	97
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

GOGA1_MOUSE
θ value	θ > 10 (rank : 655)	NC score	0.079740 (rank : 299)
Query Neighborhood Hits	455	Target Neighborhood Hits	994	Shared Neighborhood Hits	115
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GOGA2_MOUSE
θ value	θ > 10 (rank : 656)	NC score	0.073792 (rank : 389)
Query Neighborhood Hits	455	Target Neighborhood Hits	944	Shared Neighborhood Hits	117
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

GOGA3_HUMAN
θ value	θ > 10 (rank : 657)	NC score	0.078083 (rank : 322)
Query Neighborhood Hits	455	Target Neighborhood Hits	1317	Shared Neighborhood Hits	146
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

GOGA4_HUMAN
θ value	θ > 10 (rank : 658)	NC score	0.080379 (rank : 284)
Query Neighborhood Hits	455	Target Neighborhood Hits	2034	Shared Neighborhood Hits	182
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

GOGA4_MOUSE
θ value	θ > 10 (rank : 659)	NC score	0.077126 (rank : 331)
Query Neighborhood Hits	455	Target Neighborhood Hits	1939	Shared Neighborhood Hits	172
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

GOGA5_HUMAN
θ value	θ > 10 (rank : 660)	NC score	0.078811 (rank : 311)
Query Neighborhood Hits	455	Target Neighborhood Hits	1168	Shared Neighborhood Hits	128
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

GOGA6_HUMAN
θ value	θ > 10 (rank : 661)	NC score	0.070239 (rank : 442)
Query Neighborhood Hits	455	Target Neighborhood Hits	1007	Shared Neighborhood Hits	114
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

GP73_MOUSE
θ value	θ > 10 (rank : 662)	NC score	0.061569 (rank : 619)
Query Neighborhood Hits	455	Target Neighborhood Hits	506	Shared Neighborhood Hits	96
SwissProt Accessions	Q91XA2	Gene names	Golph2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

GRAP1_HUMAN
θ value	θ > 10 (rank : 663)	NC score	0.065583 (rank : 537)
Query Neighborhood Hits	455	Target Neighborhood Hits	944	Shared Neighborhood Hits	111
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

GRAP1_MOUSE
θ value	θ > 10 (rank : 664)	NC score	0.068815 (rank : 464)
Query Neighborhood Hits	455	Target Neighborhood Hits	1234	Shared Neighborhood Hits	137
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

GRAP_HUMAN
θ value	θ > 10 (rank : 665)	NC score	0.113095 (rank : 132)
Query Neighborhood Hits	455	Target Neighborhood Hits	307	Shared Neighborhood Hits	82
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
θ value	θ > 10 (rank : 666)	NC score	0.118878 (rank : 121)
Query Neighborhood Hits	455	Target Neighborhood Hits	309	Shared Neighborhood Hits	84
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

GRB2_HUMAN
θ value	θ > 10 (rank : 667)	NC score	0.131039 (rank : 91)
Query Neighborhood Hits	455	Target Neighborhood Hits	310	Shared Neighborhood Hits	84
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	θ > 10 (rank : 668)	NC score	0.130679 (rank : 93)
Query Neighborhood Hits	455	Target Neighborhood Hits	312	Shared Neighborhood Hits	84
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

GRIN1_HUMAN
θ value	θ > 10 (rank : 669)	NC score	0.073432 (rank : 393)
Query Neighborhood Hits	455	Target Neighborhood Hits	681	Shared Neighborhood Hits	93
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

GRIN1_MOUSE
θ value	θ > 10 (rank : 670)	NC score	0.066049 (rank : 527)
Query Neighborhood Hits	455	Target Neighborhood Hits	337	Shared Neighborhood Hits	80
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

GTSE1_HUMAN
θ value	θ > 10 (rank : 671)	NC score	0.050747 (rank : 846)
Query Neighborhood Hits	455	Target Neighborhood Hits	193	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

HAPIP_HUMAN
θ value	θ > 10 (rank : 672)	NC score	0.059824 (rank : 657)
Query Neighborhood Hits	455	Target Neighborhood Hits	350	Shared Neighborhood Hits	60
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

HGS_HUMAN
θ value	θ > 10 (rank : 673)	NC score	0.051212 (rank : 832)
Query Neighborhood Hits	455	Target Neighborhood Hits	517	Shared Neighborhood Hits	81
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

HGS_MOUSE
θ value	θ > 10 (rank : 674)	NC score	0.058994 (rank : 672)
Query Neighborhood Hits	455	Target Neighborhood Hits	589	Shared Neighborhood Hits	95
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HIP1R_HUMAN
θ value	θ > 10 (rank : 675)	NC score	0.058895 (rank : 673)
Query Neighborhood Hits	455	Target Neighborhood Hits	809	Shared Neighborhood Hits	98
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

HIP1R_MOUSE
θ value	θ > 10 (rank : 676)	NC score	0.064177 (rank : 570)
Query Neighborhood Hits	455	Target Neighborhood Hits	959	Shared Neighborhood Hits	108
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

HIP1_HUMAN
θ value	θ > 10 (rank : 677)	NC score	0.068121 (rank : 477)
Query Neighborhood Hits	455	Target Neighborhood Hits	1016	Shared Neighborhood Hits	118
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

HMMR_MOUSE
θ value	θ > 10 (rank : 678)	NC score	0.078076 (rank : 323)
Query Neighborhood Hits	455	Target Neighborhood Hits	1178	Shared Neighborhood Hits	122
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

HOME2_MOUSE
θ value	θ > 10 (rank : 679)	NC score	0.064617 (rank : 560)
Query Neighborhood Hits	455	Target Neighborhood Hits	882	Shared Neighborhood Hits	108
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

HOOK1_HUMAN
θ value	θ > 10 (rank : 680)	NC score	0.070537 (rank : 437)
Query Neighborhood Hits	455	Target Neighborhood Hits	942	Shared Neighborhood Hits	117
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

HOOK1_MOUSE
θ value	θ > 10 (rank : 681)	NC score	0.072767 (rank : 409)
Query Neighborhood Hits	455	Target Neighborhood Hits	910	Shared Neighborhood Hits	116
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

HOOK2_HUMAN
θ value	θ > 10 (rank : 682)	NC score	0.065922 (rank : 530)
Query Neighborhood Hits	455	Target Neighborhood Hits	714	Shared Neighborhood Hits	96
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

HOOK2_MOUSE
θ value	θ > 10 (rank : 683)	NC score	0.067951 (rank : 480)
Query Neighborhood Hits	455	Target Neighborhood Hits	736	Shared Neighborhood Hits	99
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

IASPP_HUMAN
θ value	θ > 10 (rank : 684)	NC score	0.107452 (rank : 145)
Query Neighborhood Hits	455	Target Neighborhood Hits	688	Shared Neighborhood Hits	126
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IASPP_MOUSE
θ value	θ > 10 (rank : 685)	NC score	0.114310 (rank : 130)
Query Neighborhood Hits	455	Target Neighborhood Hits	1024	Shared Neighborhood Hits	159
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IF2P_HUMAN
θ value	θ > 10 (rank : 686)	NC score	0.064334 (rank : 566)
Query Neighborhood Hits	455	Target Neighborhood Hits	889	Shared Neighborhood Hits	112
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

IF35_HUMAN
θ value	θ > 10 (rank : 687)	NC score	0.055068 (rank : 753)
Query Neighborhood Hits	455	Target Neighborhood Hits	130	Shared Neighborhood Hits	33
SwissProt Accessions	O00303, Q8N978	Gene names	EIF3S5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

IF35_MOUSE
θ value	θ > 10 (rank : 688)	NC score	0.060572 (rank : 639)
Query Neighborhood Hits	455	Target Neighborhood Hits	210	Shared Neighborhood Hits	41
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

IF3A_HUMAN
θ value	θ > 10 (rank : 689)	NC score	0.063262 (rank : 595)
Query Neighborhood Hits	455	Target Neighborhood Hits	875	Shared Neighborhood Hits	97
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

IF3A_MOUSE
θ value	θ > 10 (rank : 690)	NC score	0.065109 (rank : 550)
Query Neighborhood Hits	455	Target Neighborhood Hits	871	Shared Neighborhood Hits	99
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

IFT74_HUMAN
θ value	θ > 10 (rank : 691)	NC score	0.070722 (rank : 433)
Query Neighborhood Hits	455	Target Neighborhood Hits	949	Shared Neighborhood Hits	103
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT74_MOUSE
θ value	θ > 10 (rank : 692)	NC score	0.067525 (rank : 490)
Query Neighborhood Hits	455	Target Neighborhood Hits	939	Shared Neighborhood Hits	98
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT81_HUMAN
θ value	θ > 10 (rank : 693)	NC score	0.070514 (rank : 438)
Query Neighborhood Hits	455	Target Neighborhood Hits	893	Shared Neighborhood Hits	109
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

IFT81_MOUSE
θ value	θ > 10 (rank : 694)	NC score	0.072898 (rank : 407)
Query Neighborhood Hits	455	Target Neighborhood Hits	959	Shared Neighborhood Hits	111
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

INVO_HUMAN
θ value	θ > 10 (rank : 695)	NC score	0.072955 (rank : 404)
Query Neighborhood Hits	455	Target Neighborhood Hits	636	Shared Neighborhood Hits	113
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

INVO_MOUSE
θ value	θ > 10 (rank : 696)	NC score	0.053594 (rank : 786)
Query Neighborhood Hits	455	Target Neighborhood Hits	474	Shared Neighborhood Hits	80
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

IWS1_HUMAN
θ value	θ > 10 (rank : 697)	NC score	0.101947 (rank : 161)
Query Neighborhood Hits	455	Target Neighborhood Hits	1241	Shared Neighborhood Hits	167
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

JIP2_HUMAN
θ value	θ > 10 (rank : 698)	NC score	0.060184 (rank : 651)
Query Neighborhood Hits	455	Target Neighborhood Hits	288	Shared Neighborhood Hits	61
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

K0310_HUMAN
θ value	θ > 10 (rank : 699)	NC score	0.051228 (rank : 830)
Query Neighborhood Hits	455	Target Neighborhood Hits	420	Shared Neighborhood Hits	75
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

K0494_HUMAN
θ value	θ > 10 (rank : 700)	NC score	0.057910 (rank : 691)
Query Neighborhood Hits	455	Target Neighborhood Hits	230	Shared Neighborhood Hits	44
SwissProt Accessions	O75071	Gene names	KIAA0494
Domain Architecture	No domain graphic available
Description	Uncharacterized calcium-binding protein KIAA0494.

K0555_HUMAN
θ value	θ > 10 (rank : 701)	NC score	0.075859 (rank : 360)
Query Neighborhood Hits	455	Target Neighborhood Hits	880	Shared Neighborhood Hits	110
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

K1543_HUMAN
θ value	θ > 10 (rank : 702)	NC score	0.050967 (rank : 838)
Query Neighborhood Hits	455	Target Neighborhood Hits	435	Shared Neighborhood Hits	83
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

K1543_MOUSE
θ value	θ > 10 (rank : 703)	NC score	0.063298 (rank : 594)
Query Neighborhood Hits	455	Target Neighborhood Hits	497	Shared Neighborhood Hits	89
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

K1683_HUMAN
θ value	θ > 10 (rank : 704)	NC score	0.053845 (rank : 780)
Query Neighborhood Hits	455	Target Neighborhood Hits	240	Shared Neighborhood Hits	58
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

K1802_HUMAN
θ value	θ > 10 (rank : 705)	NC score	0.070550 (rank : 436)
Query Neighborhood Hits	455	Target Neighborhood Hits	1378	Shared Neighborhood Hits	135
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

KI67_HUMAN
θ value	θ > 10 (rank : 706)	NC score	0.075861 (rank : 359)
Query Neighborhood Hits	455	Target Neighborhood Hits	581	Shared Neighborhood Hits	98
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

KIF4A_HUMAN
θ value	θ > 10 (rank : 707)	NC score	0.051941 (rank : 814)
Query Neighborhood Hits	455	Target Neighborhood Hits	1159	Shared Neighborhood Hits	118
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

KIF5C_HUMAN
θ value	θ > 10 (rank : 708)	NC score	0.055427 (rank : 747)
Query Neighborhood Hits	455	Target Neighborhood Hits	974	Shared Neighborhood Hits	121
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

KINH_HUMAN
θ value	θ > 10 (rank : 709)	NC score	0.060812 (rank : 634)
Query Neighborhood Hits	455	Target Neighborhood Hits	1231	Shared Neighborhood Hits	126
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

KINH_MOUSE
θ value	θ > 10 (rank : 710)	NC score	0.061543 (rank : 621)
Query Neighborhood Hits	455	Target Neighborhood Hits	1082	Shared Neighborhood Hits	123
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

KMHN1_HUMAN
θ value	θ > 10 (rank : 711)	NC score	0.066522 (rank : 512)
Query Neighborhood Hits	455	Target Neighborhood Hits	950	Shared Neighborhood Hits	98
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

KNTC2_HUMAN
θ value	θ > 10 (rank : 712)	NC score	0.061913 (rank : 609)
Query Neighborhood Hits	455	Target Neighborhood Hits	673	Shared Neighborhood Hits	89
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

KNTC2_MOUSE
θ value	θ > 10 (rank : 713)	NC score	0.060191 (rank : 649)
Query Neighborhood Hits	455	Target Neighborhood Hits	692	Shared Neighborhood Hits	89
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

KTN1_HUMAN
θ value	θ > 10 (rank : 714)	NC score	0.065768 (rank : 532)
Query Neighborhood Hits	455	Target Neighborhood Hits	1197	Shared Neighborhood Hits	122
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

KTN1_MOUSE
θ value	θ > 10 (rank : 715)	NC score	0.074372 (rank : 381)
Query Neighborhood Hits	455	Target Neighborhood Hits	1324	Shared Neighborhood Hits	139
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

LAD1_HUMAN
θ value	θ > 10 (rank : 716)	NC score	0.090359 (rank : 214)
Query Neighborhood Hits	455	Target Neighborhood Hits	441	Shared Neighborhood Hits	94
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

LAD1_MOUSE
θ value	θ > 10 (rank : 717)	NC score	0.095308 (rank : 191)
Query Neighborhood Hits	455	Target Neighborhood Hits	391	Shared Neighborhood Hits	87
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

LARP4_MOUSE
θ value	θ > 10 (rank : 718)	NC score	0.073795 (rank : 388)
Query Neighborhood Hits	455	Target Neighborhood Hits	260	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

LCP2_HUMAN
θ value	θ > 10 (rank : 719)	NC score	0.066481 (rank : 514)
Query Neighborhood Hits	455	Target Neighborhood Hits	531	Shared Neighborhood Hits	95
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LIPA2_HUMAN
θ value	θ > 10 (rank : 720)	NC score	0.062897 (rank : 600)
Query Neighborhood Hits	455	Target Neighborhood Hits	1044	Shared Neighborhood Hits	119
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

LIPA2_MOUSE
θ value	θ > 10 (rank : 721)	NC score	0.067928 (rank : 481)
Query Neighborhood Hits	455	Target Neighborhood Hits	1282	Shared Neighborhood Hits	140
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

LIPA3_HUMAN
θ value	θ > 10 (rank : 722)	NC score	0.057013 (rank : 711)
Query Neighborhood Hits	455	Target Neighborhood Hits	828	Shared Neighborhood Hits	106
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

LIPB1_HUMAN
θ value	θ > 10 (rank : 723)	NC score	0.051708 (rank : 819)
Query Neighborhood Hits	455	Target Neighborhood Hits	640	Shared Neighborhood Hits	95
SwissProt Accessions	Q86W92, O75336, Q86X70, Q9NY03, Q9ULJ0	Gene names	PPFIBP1, KIAA1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2).

LIPB1_MOUSE
θ value	θ > 10 (rank : 724)	NC score	0.055417 (rank : 748)
Query Neighborhood Hits	455	Target Neighborhood Hits	727	Shared Neighborhood Hits	98
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

LIPS_HUMAN
θ value	θ > 10 (rank : 725)	NC score	0.051223 (rank : 831)
Query Neighborhood Hits	455	Target Neighborhood Hits	314	Shared Neighborhood Hits	82
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

LMNA_HUMAN
θ value	θ > 10 (rank : 726)	NC score	0.053081 (rank : 798)
Query Neighborhood Hits	455	Target Neighborhood Hits	653	Shared Neighborhood Hits	98
SwissProt Accessions	P02545, P02546, Q969I8, Q96JA2	Gene names	LMNA, LMN1
Domain Architecture
Description	Lamin-A/C (70 kDa lamin) (NY-REN-32 antigen).

LMNA_MOUSE
θ value	θ > 10 (rank : 727)	NC score	0.053180 (rank : 796)
Query Neighborhood Hits	455	Target Neighborhood Hits	661	Shared Neighborhood Hits	100
SwissProt Accessions	P48678, P11516, P97859, Q3TIH0, Q3TTS8, Q3UCA0, Q3UCJ8, Q91WF2, Q9DC21	Gene names	Lmna, Lmn1
Domain Architecture
Description	Lamin-A/C.

LMNB1_HUMAN
θ value	θ > 10 (rank : 728)	NC score	0.057987 (rank : 688)
Query Neighborhood Hits	455	Target Neighborhood Hits	714	Shared Neighborhood Hits	102
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

LMNB1_MOUSE
θ value	θ > 10 (rank : 729)	NC score	0.056930 (rank : 712)
Query Neighborhood Hits	455	Target Neighborhood Hits	719	Shared Neighborhood Hits	99
SwissProt Accessions	P14733, Q61791	Gene names	Lmnb1
Domain Architecture
Description	Lamin-B1.

LMNB2_HUMAN
θ value	θ > 10 (rank : 730)	NC score	0.055752 (rank : 738)
Query Neighborhood Hits	455	Target Neighborhood Hits	723	Shared Neighborhood Hits	86
SwissProt Accessions	Q03252, O75292, Q14734, Q96DF6	Gene names	LMNB2, LMN2
Domain Architecture
Description	Lamin-B2.

LMNB2_MOUSE
θ value	θ > 10 (rank : 731)	NC score	0.054775 (rank : 761)
Query Neighborhood Hits	455	Target Neighborhood Hits	674	Shared Neighborhood Hits	93
SwissProt Accessions	P21619, P48680, Q8CGB1	Gene names	Lmnb2
Domain Architecture
Description	Lamin-B2.

LR37A_HUMAN
θ value	θ > 10 (rank : 732)	NC score	0.066159 (rank : 521)
Query Neighborhood Hits	455	Target Neighborhood Hits	720	Shared Neighborhood Hits	92
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

LRC45_HUMAN
θ value	θ > 10 (rank : 733)	NC score	0.065455 (rank : 540)
Query Neighborhood Hits	455	Target Neighborhood Hits	933	Shared Neighborhood Hits	110
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRC45_MOUSE
θ value	θ > 10 (rank : 734)	NC score	0.065243 (rank : 546)
Query Neighborhood Hits	455	Target Neighborhood Hits	959	Shared Neighborhood Hits	102
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRRF1_MOUSE
θ value	θ > 10 (rank : 735)	NC score	0.064094 (rank : 574)
Query Neighborhood Hits	455	Target Neighborhood Hits	440	Shared Neighborhood Hits	76
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

LRRF2_HUMAN
θ value	θ > 10 (rank : 736)	NC score	0.071143 (rank : 429)
Query Neighborhood Hits	455	Target Neighborhood Hits	791	Shared Neighborhood Hits	105
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

LRRF2_MOUSE
θ value	θ > 10 (rank : 737)	NC score	0.062519 (rank : 604)
Query Neighborhood Hits	455	Target Neighborhood Hits	556	Shared Neighborhood Hits	87
SwissProt Accessions	Q91WK0, Q8BVD1, Q9CU89	Gene names	Lrrfip2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

LUZP1_HUMAN
θ value	θ > 10 (rank : 738)	NC score	0.057866 (rank : 696)
Query Neighborhood Hits	455	Target Neighborhood Hits	739	Shared Neighborhood Hits	89
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

LUZP1_MOUSE
θ value	θ > 10 (rank : 739)	NC score	0.070393 (rank : 441)
Query Neighborhood Hits	455	Target Neighborhood Hits	940	Shared Neighborhood Hits	116
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

MACF1_HUMAN
θ value	θ > 10 (rank : 740)	NC score	0.054447 (rank : 767)
Query Neighborhood Hits	455	Target Neighborhood Hits	1341	Shared Neighborhood Hits	134
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF1_MOUSE
θ value	θ > 10 (rank : 741)	NC score	0.051700 (rank : 820)
Query Neighborhood Hits	455	Target Neighborhood Hits	1313	Shared Neighborhood Hits	132
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

MACF4_HUMAN
θ value	θ > 10 (rank : 742)	NC score	0.060211 (rank : 648)
Query Neighborhood Hits	455	Target Neighborhood Hits	1321	Shared Neighborhood Hits	135
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MACOI_HUMAN
θ value	θ > 10 (rank : 743)	NC score	0.057986 (rank : 689)
Query Neighborhood Hits	455	Target Neighborhood Hits	650	Shared Neighborhood Hits	90
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

MACOI_MOUSE
θ value	θ > 10 (rank : 744)	NC score	0.059607 (rank : 662)
Query Neighborhood Hits	455	Target Neighborhood Hits	620	Shared Neighborhood Hits	89
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

MAGE1_HUMAN
θ value	θ > 10 (rank : 745)	NC score	0.099540 (rank : 170)
Query Neighborhood Hits	455	Target Neighborhood Hits	1389	Shared Neighborhood Hits	178
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MAP1A_HUMAN
θ value	θ > 10 (rank : 746)	NC score	0.102107 (rank : 159)
Query Neighborhood Hits	455	Target Neighborhood Hits	1626	Shared Neighborhood Hits	217
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MAP1B_HUMAN
θ value	θ > 10 (rank : 747)	NC score	0.076876 (rank : 336)
Query Neighborhood Hits	455	Target Neighborhood Hits	903	Shared Neighborhood Hits	132
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MAP1B_MOUSE
θ value	θ > 10 (rank : 748)	NC score	0.075177 (rank : 367)
Query Neighborhood Hits	455	Target Neighborhood Hits	977	Shared Neighborhood Hits	148
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MAP2_HUMAN
θ value	θ > 10 (rank : 749)	NC score	0.065722 (rank : 535)
Query Neighborhood Hits	455	Target Neighborhood Hits	348	Shared Neighborhood Hits	73
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

MAP4_HUMAN
θ value	θ > 10 (rank : 750)	NC score	0.109778 (rank : 138)
Query Neighborhood Hits	455	Target Neighborhood Hits	428	Shared Neighborhood Hits	84
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MAP4_MOUSE
θ value	θ > 10 (rank : 751)	NC score	0.093868 (rank : 197)
Query Neighborhood Hits	455	Target Neighborhood Hits	409	Shared Neighborhood Hits	77
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MAVS_HUMAN
θ value	θ > 10 (rank : 752)	NC score	0.056016 (rank : 734)
Query Neighborhood Hits	455	Target Neighborhood Hits	271	Shared Neighborhood Hits	60
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

MBB1A_HUMAN
θ value	θ > 10 (rank : 753)	NC score	0.063395 (rank : 592)
Query Neighborhood Hits	455	Target Neighborhood Hits	665	Shared Neighborhood Hits	101
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MBD6_HUMAN
θ value	θ > 10 (rank : 754)	NC score	0.074626 (rank : 377)
Query Neighborhood Hits	455	Target Neighborhood Hits	349	Shared Neighborhood Hits	62
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MD1L1_HUMAN
θ value	θ > 10 (rank : 755)	NC score	0.063979 (rank : 578)
Query Neighborhood Hits	455	Target Neighborhood Hits	893	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

MD1L1_MOUSE
θ value	θ > 10 (rank : 756)	NC score	0.067165 (rank : 496)
Query Neighborhood Hits	455	Target Neighborhood Hits	1001	Shared Neighborhood Hits	112
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

MFAP1_MOUSE
θ value	θ > 10 (rank : 757)	NC score	0.050198 (rank : 855)
Query Neighborhood Hits	455	Target Neighborhood Hits	353	Shared Neighborhood Hits	59
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

MILK1_MOUSE
θ value	θ > 10 (rank : 758)	NC score	0.061411 (rank : 626)
Query Neighborhood Hits	455	Target Neighborhood Hits	788	Shared Neighborhood Hits	119
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MIPO1_HUMAN
θ value	θ > 10 (rank : 759)	NC score	0.058757 (rank : 675)
Query Neighborhood Hits	455	Target Neighborhood Hits	486	Shared Neighborhood Hits	84
SwissProt Accessions	Q8TD10, Q7Z3J0, Q8IV14	Gene names	MIPOL1
Domain Architecture	No domain graphic available
Description	Mirror-image polydactyly gene 1 protein.

MKL1_MOUSE
θ value	θ > 10 (rank : 760)	NC score	0.051691 (rank : 821)
Query Neighborhood Hits	455	Target Neighborhood Hits	667	Shared Neighborhood Hits	103
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

MLL3_HUMAN
θ value	θ > 10 (rank : 761)	NC score	0.073543 (rank : 391)
Query Neighborhood Hits	455	Target Neighborhood Hits	1644	Shared Neighborhood Hits	179
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL3_MOUSE
θ value	θ > 10 (rank : 762)	NC score	0.065282 (rank : 545)
Query Neighborhood Hits	455	Target Neighborhood Hits	1399	Shared Neighborhood Hits	145
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MMRN1_HUMAN
θ value	θ > 10 (rank : 763)	NC score	0.053112 (rank : 797)
Query Neighborhood Hits	455	Target Neighborhood Hits	636	Shared Neighborhood Hits	83
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

MNT_HUMAN
θ value	θ > 10 (rank : 764)	NC score	0.053018 (rank : 800)
Query Neighborhood Hits	455	Target Neighborhood Hits	496	Shared Neighborhood Hits	87
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MNT_MOUSE
θ value	θ > 10 (rank : 765)	NC score	0.051398 (rank : 826)
Query Neighborhood Hits	455	Target Neighborhood Hits	432	Shared Neighborhood Hits	75
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MPP9_HUMAN
θ value	θ > 10 (rank : 766)	NC score	0.056612 (rank : 721)
Query Neighborhood Hits	455	Target Neighborhood Hits	529	Shared Neighborhood Hits	73
SwissProt Accessions	Q99550, Q9H976	Gene names	MPHOSPH9, MPP9
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 9.

MTSS1_HUMAN
θ value	θ > 10 (rank : 767)	NC score	0.065142 (rank : 549)
Query Neighborhood Hits	455	Target Neighborhood Hits	504	Shared Neighborhood Hits	99
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

MTSS1_MOUSE
θ value	θ > 10 (rank : 768)	NC score	0.083313 (rank : 256)
Query Neighborhood Hits	455	Target Neighborhood Hits	592	Shared Neighborhood Hits	117
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

MUC1_MOUSE
θ value	θ > 10 (rank : 769)	NC score	0.064171 (rank : 571)
Query Neighborhood Hits	455	Target Neighborhood Hits	388	Shared Neighborhood Hits	49
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

MUC5B_HUMAN
θ value	θ > 10 (rank : 770)	NC score	0.060185 (rank : 650)
Query Neighborhood Hits	455	Target Neighborhood Hits	1020	Shared Neighborhood Hits	89
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MUCDL_HUMAN
θ value	θ > 10 (rank : 771)	NC score	0.054741 (rank : 763)
Query Neighborhood Hits	455	Target Neighborhood Hits	777	Shared Neighborhood Hits	102
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MY18A_HUMAN
θ value	θ > 10 (rank : 772)	NC score	0.078393 (rank : 318)
Query Neighborhood Hits	455	Target Neighborhood Hits	1929	Shared Neighborhood Hits	174
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MY18A_MOUSE
θ value	θ > 10 (rank : 773)	NC score	0.079746 (rank : 298)
Query Neighborhood Hits	455	Target Neighborhood Hits	1989	Shared Neighborhood Hits	178
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH13_HUMAN
θ value	θ > 10 (rank : 774)	NC score	0.067185 (rank : 495)
Query Neighborhood Hits	455	Target Neighborhood Hits	1504	Shared Neighborhood Hits	139
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYH14_HUMAN
θ value	θ > 10 (rank : 775)	NC score	0.062026 (rank : 608)
Query Neighborhood Hits	455	Target Neighborhood Hits	995	Shared Neighborhood Hits	105
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH1_HUMAN
θ value	θ > 10 (rank : 776)	NC score	0.066130 (rank : 523)
Query Neighborhood Hits	455	Target Neighborhood Hits	1478	Shared Neighborhood Hits	144
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

MYH1_MOUSE
θ value	θ > 10 (rank : 777)	NC score	0.065444 (rank : 541)
Query Neighborhood Hits	455	Target Neighborhood Hits	1461	Shared Neighborhood Hits	141
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH2_HUMAN
θ value	θ > 10 (rank : 778)	NC score	0.066001 (rank : 528)
Query Neighborhood Hits	455	Target Neighborhood Hits	1491	Shared Neighborhood Hits	147
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

MYH3_HUMAN
θ value	θ > 10 (rank : 779)	NC score	0.066793 (rank : 501)
Query Neighborhood Hits	455	Target Neighborhood Hits	1660	Shared Neighborhood Hits	153
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

MYH4_HUMAN
θ value	θ > 10 (rank : 780)	NC score	0.063920 (rank : 581)
Query Neighborhood Hits	455	Target Neighborhood Hits	1377	Shared Neighborhood Hits	133
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

MYH4_MOUSE
θ value	θ > 10 (rank : 781)	NC score	0.065035 (rank : 551)
Query Neighborhood Hits	455	Target Neighborhood Hits	1476	Shared Neighborhood Hits	146
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYH6_HUMAN
θ value	θ > 10 (rank : 782)	NC score	0.064014 (rank : 577)
Query Neighborhood Hits	455	Target Neighborhood Hits	1426	Shared Neighborhood Hits	140
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH8_HUMAN
θ value	θ > 10 (rank : 783)	NC score	0.068454 (rank : 468)
Query Neighborhood Hits	455	Target Neighborhood Hits	1610	Shared Neighborhood Hits	159
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH8_MOUSE
θ value	θ > 10 (rank : 784)	NC score	0.066519 (rank : 513)
Query Neighborhood Hits	455	Target Neighborhood Hits	1600	Shared Neighborhood Hits	151
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYO15_MOUSE
θ value	θ > 10 (rank : 785)	NC score	0.050068 (rank : 858)
Query Neighborhood Hits	455	Target Neighborhood Hits	467	Shared Neighborhood Hits	97
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

MYO1F_HUMAN
θ value	θ > 10 (rank : 786)	NC score	0.083338 (rank : 255)
Query Neighborhood Hits	455	Target Neighborhood Hits	275	Shared Neighborhood Hits	94
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

MYO1F_MOUSE
θ value	θ > 10 (rank : 787)	NC score	0.083066 (rank : 257)
Query Neighborhood Hits	455	Target Neighborhood Hits	262	Shared Neighborhood Hits	88
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

MYO5A_HUMAN
θ value	θ > 10 (rank : 788)	NC score	0.057815 (rank : 697)
Query Neighborhood Hits	455	Target Neighborhood Hits	1092	Shared Neighborhood Hits	126
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

MYO5A_MOUSE
θ value	θ > 10 (rank : 789)	NC score	0.056216 (rank : 729)
Query Neighborhood Hits	455	Target Neighborhood Hits	1117	Shared Neighborhood Hits	118
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

MYO5B_HUMAN
θ value	θ > 10 (rank : 790)	NC score	0.055479 (rank : 745)
Query Neighborhood Hits	455	Target Neighborhood Hits	911	Shared Neighborhood Hits	106
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

MYO5C_HUMAN
θ value	θ > 10 (rank : 791)	NC score	0.067802 (rank : 485)
Query Neighborhood Hits	455	Target Neighborhood Hits	1206	Shared Neighborhood Hits	130
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

NAF1_HUMAN
θ value	θ > 10 (rank : 792)	NC score	0.063418 (rank : 591)
Query Neighborhood Hits	455	Target Neighborhood Hits	937	Shared Neighborhood Hits	110
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

NAF1_MOUSE
θ value	θ > 10 (rank : 793)	NC score	0.061769 (rank : 613)
Query Neighborhood Hits	455	Target Neighborhood Hits	852	Shared Neighborhood Hits	102
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

NCF1_HUMAN
θ value	θ > 10 (rank : 794)	NC score	0.122981 (rank : 114)
Query Neighborhood Hits	455	Target Neighborhood Hits	198	Shared Neighborhood Hits	74
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

NCF1_MOUSE
θ value	θ > 10 (rank : 795)	NC score	0.125525 (rank : 105)
Query Neighborhood Hits	455	Target Neighborhood Hits	198	Shared Neighborhood Hits	75
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

NCF4_HUMAN
θ value	θ > 10 (rank : 796)	NC score	0.123922 (rank : 112)
Query Neighborhood Hits	455	Target Neighborhood Hits	161	Shared Neighborhood Hits	62
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCF4_MOUSE
θ value	θ > 10 (rank : 797)	NC score	0.135205 (rank : 80)
Query Neighborhood Hits	455	Target Neighborhood Hits	177	Shared Neighborhood Hits	69
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCK2_HUMAN
θ value	θ > 10 (rank : 798)	NC score	0.134267 (rank : 84)
Query Neighborhood Hits	455	Target Neighborhood Hits	310	Shared Neighborhood Hits	85
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

NCOR2_HUMAN
θ value	θ > 10 (rank : 799)	NC score	0.077498 (rank : 329)
Query Neighborhood Hits	455	Target Neighborhood Hits	870	Shared Neighborhood Hits	129
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NDE1_HUMAN
θ value	θ > 10 (rank : 800)	NC score	0.058143 (rank : 685)
Query Neighborhood Hits	455	Target Neighborhood Hits	823	Shared Neighborhood Hits	105
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

NEB2_HUMAN
θ value	θ > 10 (rank : 801)	NC score	0.054898 (rank : 759)
Query Neighborhood Hits	455	Target Neighborhood Hits	883	Shared Neighborhood Hits	110
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	θ > 10 (rank : 802)	NC score	0.058624 (rank : 677)
Query Neighborhood Hits	455	Target Neighborhood Hits	889	Shared Neighborhood Hits	110
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEBL_HUMAN
θ value	θ > 10 (rank : 803)	NC score	0.162785 (rank : 54)
Query Neighborhood Hits	455	Target Neighborhood Hits	457	Shared Neighborhood Hits	130
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

NEBU_HUMAN
θ value	θ > 10 (rank : 804)	NC score	0.126983 (rank : 100)
Query Neighborhood Hits	455	Target Neighborhood Hits	420	Shared Neighborhood Hits	102
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

NEMO_HUMAN
θ value	θ > 10 (rank : 805)	NC score	0.069161 (rank : 459)
Query Neighborhood Hits	455	Target Neighborhood Hits	820	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

NEMO_MOUSE
θ value	θ > 10 (rank : 806)	NC score	0.060882 (rank : 631)
Query Neighborhood Hits	455	Target Neighborhood Hits	658	Shared Neighborhood Hits	96
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

NEUM_HUMAN
θ value	θ > 10 (rank : 807)	NC score	0.054833 (rank : 760)
Query Neighborhood Hits	455	Target Neighborhood Hits	132	Shared Neighborhood Hits	35
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

NFRKB_MOUSE
θ value	θ > 10 (rank : 808)	NC score	0.057943 (rank : 690)
Query Neighborhood Hits	455	Target Neighborhood Hits	393	Shared Neighborhood Hits	68
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

NIN_HUMAN
θ value	θ > 10 (rank : 809)	NC score	0.070819 (rank : 432)
Query Neighborhood Hits	455	Target Neighborhood Hits	1416	Shared Neighborhood Hits	134
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

NIN_MOUSE
θ value	θ > 10 (rank : 810)	NC score	0.069210 (rank : 458)
Query Neighborhood Hits	455	Target Neighborhood Hits	1376	Shared Neighborhood Hits	139
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

NIPBL_HUMAN
θ value	θ > 10 (rank : 811)	NC score	0.082588 (rank : 259)
Query Neighborhood Hits	455	Target Neighborhood Hits	1311	Shared Neighborhood Hits	160
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NOLC1_HUMAN
θ value	θ > 10 (rank : 812)	NC score	0.064306 (rank : 567)
Query Neighborhood Hits	455	Target Neighborhood Hits	452	Shared Neighborhood Hits	58
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

NOXO1_HUMAN
θ value	θ > 10 (rank : 813)	NC score	0.063108 (rank : 597)
Query Neighborhood Hits	455	Target Neighborhood Hits	100	Shared Neighborhood Hits	44
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

NOXO1_MOUSE
θ value	θ > 10 (rank : 814)	NC score	0.082827 (rank : 258)
Query Neighborhood Hits	455	Target Neighborhood Hits	114	Shared Neighborhood Hits	54
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

NPBL_MOUSE
θ value	θ > 10 (rank : 815)	NC score	0.064665 (rank : 557)
Query Neighborhood Hits	455	Target Neighborhood Hits	1041	Shared Neighborhood Hits	128
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NPHP1_MOUSE
θ value	θ > 10 (rank : 816)	NC score	0.095810 (rank : 187)
Query Neighborhood Hits	455	Target Neighborhood Hits	267	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

NTBP1_MOUSE
θ value	θ > 10 (rank : 817)	NC score	0.056738 (rank : 716)
Query Neighborhood Hits	455	Target Neighborhood Hits	528	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BRM2, Q8CAA8	Gene names	Scyl1bp1, Ntklbp1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (mNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

NU214_HUMAN
θ value	θ > 10 (rank : 818)	NC score	0.073268 (rank : 399)
Query Neighborhood Hits	455	Target Neighborhood Hits	657	Shared Neighborhood Hits	95
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

NUF2_MOUSE
θ value	θ > 10 (rank : 819)	NC score	0.069473 (rank : 452)
Query Neighborhood Hits	455	Target Neighborhood Hits	585	Shared Neighborhood Hits	91
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

NUMA1_HUMAN
θ value	θ > 10 (rank : 820)	NC score	0.075815 (rank : 361)
Query Neighborhood Hits	455	Target Neighborhood Hits	1523	Shared Neighborhood Hits	156
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

OFD1_HUMAN
θ value	θ > 10 (rank : 821)	NC score	0.074519 (rank : 380)
Query Neighborhood Hits	455	Target Neighborhood Hits	753	Shared Neighborhood Hits	95
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

OGFR_MOUSE
θ value	θ > 10 (rank : 822)	NC score	0.081921 (rank : 268)
Query Neighborhood Hits	455	Target Neighborhood Hits	584	Shared Neighborhood Hits	99
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

OPTN_HUMAN
θ value	θ > 10 (rank : 823)	NC score	0.067864 (rank : 482)
Query Neighborhood Hits	455	Target Neighborhood Hits	827	Shared Neighborhood Hits	111
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

OPTN_MOUSE
θ value	θ > 10 (rank : 824)	NC score	0.073306 (rank : 398)
Query Neighborhood Hits	455	Target Neighborhood Hits	1120	Shared Neighborhood Hits	124
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

OSTF1_HUMAN
θ value	θ > 10 (rank : 825)	NC score	0.108631 (rank : 141)
Query Neighborhood Hits	455	Target Neighborhood Hits	466	Shared Neighborhood Hits	80
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

OSTF1_MOUSE
θ value	θ > 10 (rank : 826)	NC score	0.106707 (rank : 147)
Query Neighborhood Hits	455	Target Neighborhood Hits	467	Shared Neighborhood Hits	80
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

OXR1_MOUSE
θ value	θ > 10 (rank : 827)	NC score	0.053708 (rank : 784)
Query Neighborhood Hits	455	Target Neighborhood Hits	516	Shared Neighborhood Hits	93
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

PCNT_HUMAN
θ value	θ > 10 (rank : 828)	NC score	0.089550 (rank : 219)
Query Neighborhood Hits	455	Target Neighborhood Hits	1551	Shared Neighborhood Hits	167
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

PCQAP_HUMAN
θ value	θ > 10 (rank : 829)	NC score	0.061831 (rank : 612)
Query Neighborhood Hits	455	Target Neighborhood Hits	549	Shared Neighborhood Hits	75
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PCQAP_MOUSE
θ value	θ > 10 (rank : 830)	NC score	0.055559 (rank : 743)
Query Neighborhood Hits	455	Target Neighborhood Hits	506	Shared Neighborhood Hits	77
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

PEPL_MOUSE
θ value	θ > 10 (rank : 831)	NC score	0.064509 (rank : 562)
Query Neighborhood Hits	455	Target Neighborhood Hits	1105	Shared Neighborhood Hits	125
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

PEX13_HUMAN
θ value	θ > 10 (rank : 832)	NC score	0.080378 (rank : 285)
Query Neighborhood Hits	455	Target Neighborhood Hits	128	Shared Neighborhood Hits	58
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PEX13_MOUSE
θ value	θ > 10 (rank : 833)	NC score	0.079615 (rank : 302)
Query Neighborhood Hits	455	Target Neighborhood Hits	126	Shared Neighborhood Hits	58
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PHLB1_HUMAN
θ value	θ > 10 (rank : 834)	NC score	0.061669 (rank : 616)
Query Neighborhood Hits	455	Target Neighborhood Hits	1038	Shared Neighborhood Hits	151
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PHLB2_HUMAN
θ value	θ > 10 (rank : 835)	NC score	0.052783 (rank : 804)
Query Neighborhood Hits	455	Target Neighborhood Hits	964	Shared Neighborhood Hits	111
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PHLB2_MOUSE
θ value	θ > 10 (rank : 836)	NC score	0.056664 (rank : 719)
Query Neighborhood Hits	455	Target Neighborhood Hits	1016	Shared Neighborhood Hits	116
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PHLB3_HUMAN
θ value	θ > 10 (rank : 837)	NC score	0.053952 (rank : 775)
Query Neighborhood Hits	455	Target Neighborhood Hits	304	Shared Neighborhood Hits	52
SwissProt Accessions	Q6NSJ2, Q8N7Z4	Gene names	PHLDB3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 3.

PI5PA_HUMAN
θ value	θ > 10 (rank : 838)	NC score	0.056647 (rank : 720)
Query Neighborhood Hits	455	Target Neighborhood Hits	749	Shared Neighborhood Hits	109
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PIBF1_HUMAN
θ value	θ > 10 (rank : 839)	NC score	0.077075 (rank : 332)
Query Neighborhood Hits	455	Target Neighborhood Hits	1041	Shared Neighborhood Hits	124
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

PININ_HUMAN
θ value	θ > 10 (rank : 840)	NC score	0.064128 (rank : 573)
Query Neighborhood Hits	455	Target Neighborhood Hits	753	Shared Neighborhood Hits	106
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PININ_MOUSE
θ value	θ > 10 (rank : 841)	NC score	0.067511 (rank : 491)
Query Neighborhood Hits	455	Target Neighborhood Hits	777	Shared Neighborhood Hits	111
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

PLCG1_HUMAN
θ value	θ > 10 (rank : 842)	NC score	0.076968 (rank : 334)
Query Neighborhood Hits	455	Target Neighborhood Hits	293	Shared Neighborhood Hits	76
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG1_MOUSE
θ value	θ > 10 (rank : 843)	NC score	0.094906 (rank : 193)
Query Neighborhood Hits	455	Target Neighborhood Hits	314	Shared Neighborhood Hits	80
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG2_HUMAN
θ value	θ > 10 (rank : 844)	NC score	0.079724 (rank : 300)
Query Neighborhood Hits	455	Target Neighborhood Hits	280	Shared Neighborhood Hits	74
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

PLEC1_HUMAN
θ value	θ > 10 (rank : 845)	NC score	0.059316 (rank : 666)
Query Neighborhood Hits	455	Target Neighborhood Hits	1326	Shared Neighborhood Hits	135
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

PO121_HUMAN
θ value	θ > 10 (rank : 846)	NC score	0.068972 (rank : 462)
Query Neighborhood Hits	455	Target Neighborhood Hits	344	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

POF1B_MOUSE
θ value	θ > 10 (rank : 847)	NC score	0.052587 (rank : 809)
Query Neighborhood Hits	455	Target Neighborhood Hits	530	Shared Neighborhood Hits	74
SwissProt Accessions	Q8K4L4, Q8C3A2	Gene names	Pof1b
Domain Architecture	No domain graphic available
Description	Protein POF1B.

PPIP2_MOUSE
θ value	θ > 10 (rank : 848)	NC score	0.050271 (rank : 854)
Query Neighborhood Hits	455	Target Neighborhood Hits	308	Shared Neighborhood Hits	64
SwissProt Accessions	Q99M15, Q9Z189	Gene names	Pstpip2, Mayp
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2 (Macrophage actin-associated tyrosine-phosphorylated protein) (pp37).

PRAX_HUMAN
θ value	θ > 10 (rank : 849)	NC score	0.075761 (rank : 363)
Query Neighborhood Hits	455	Target Neighborhood Hits	215	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

PRAX_MOUSE
θ value	θ > 10 (rank : 850)	NC score	0.059244 (rank : 667)
Query Neighborhood Hits	455	Target Neighborhood Hits	199	Shared Neighborhood Hits	43
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

PRB3_HUMAN
θ value	θ > 10 (rank : 851)	NC score	0.072196 (rank : 417)
Query Neighborhood Hits	455	Target Neighborhood Hits	318	Shared Neighborhood Hits	52
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 852)	NC score	0.075053 (rank : 370)
Query Neighborhood Hits	455	Target Neighborhood Hits	330	Shared Neighborhood Hits	58
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRP1_HUMAN
θ value	θ > 10 (rank : 853)	NC score	0.086046 (rank : 241)
Query Neighborhood Hits	455	Target Neighborhood Hits	385	Shared Neighborhood Hits	65
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 854)	NC score	0.097857 (rank : 177)
Query Neighborhood Hits	455	Target Neighborhood Hits	347	Shared Neighborhood Hits	56
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRR13_HUMAN
θ value	θ > 10 (rank : 855)	NC score	0.050459 (rank : 851)
Query Neighborhood Hits	455	Target Neighborhood Hits	105	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PSL1_HUMAN
θ value	θ > 10 (rank : 856)	NC score	0.068005 (rank : 479)
Query Neighborhood Hits	455	Target Neighborhood Hits	650	Shared Neighborhood Hits	120
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RABE1_HUMAN
θ value	θ > 10 (rank : 857)	NC score	0.072203 (rank : 415)
Query Neighborhood Hits	455	Target Neighborhood Hits	1104	Shared Neighborhood Hits	127
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RABE1_MOUSE
θ value	θ > 10 (rank : 858)	NC score	0.070563 (rank : 435)
Query Neighborhood Hits	455	Target Neighborhood Hits	1105	Shared Neighborhood Hits	126
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

RABE2_HUMAN
θ value	θ > 10 (rank : 859)	NC score	0.050706 (rank : 849)
Query Neighborhood Hits	455	Target Neighborhood Hits	545	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H5N1	Gene names	RABEP2, RABPT5B
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

RABE2_MOUSE
θ value	θ > 10 (rank : 860)	NC score	0.053558 (rank : 787)
Query Neighborhood Hits	455	Target Neighborhood Hits	598	Shared Neighborhood Hits	86
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

RAD50_HUMAN
θ value	θ > 10 (rank : 861)	NC score	0.076862 (rank : 337)
Query Neighborhood Hits	455	Target Neighborhood Hits	1317	Shared Neighborhood Hits	131
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

RAD50_MOUSE
θ value	θ > 10 (rank : 862)	NC score	0.076638 (rank : 345)
Query Neighborhood Hits	455	Target Neighborhood Hits	1366	Shared Neighborhood Hits	137
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

RAI14_HUMAN
θ value	θ > 10 (rank : 863)	NC score	0.051867 (rank : 816)
Query Neighborhood Hits	455	Target Neighborhood Hits	1367	Shared Neighborhood Hits	123
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

RAI14_MOUSE
θ value	θ > 10 (rank : 864)	NC score	0.065482 (rank : 539)
Query Neighborhood Hits	455	Target Neighborhood Hits	1505	Shared Neighborhood Hits	158
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

RAPH1_HUMAN
θ value	θ > 10 (rank : 865)	NC score	0.072717 (rank : 411)
Query Neighborhood Hits	455	Target Neighborhood Hits	593	Shared Neighborhood Hits	89
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RB6I2_HUMAN
θ value	θ > 10 (rank : 866)	NC score	0.072148 (rank : 419)
Query Neighborhood Hits	455	Target Neighborhood Hits	1584	Shared Neighborhood Hits	146
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RB6I2_MOUSE
θ value	θ > 10 (rank : 867)	NC score	0.071263 (rank : 428)
Query Neighborhood Hits	455	Target Neighborhood Hits	1433	Shared Neighborhood Hits	137
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

RBCC1_HUMAN
θ value	θ > 10 (rank : 868)	NC score	0.063190 (rank : 596)
Query Neighborhood Hits	455	Target Neighborhood Hits	1023	Shared Neighborhood Hits	109
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

RBCC1_MOUSE
θ value	θ > 10 (rank : 869)	NC score	0.064981 (rank : 552)
Query Neighborhood Hits	455	Target Neighborhood Hits	1048	Shared Neighborhood Hits	116
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

RBM25_HUMAN
θ value	θ > 10 (rank : 870)	NC score	0.055208 (rank : 752)
Query Neighborhood Hits	455	Target Neighborhood Hits	682	Shared Neighborhood Hits	87
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

RBP24_HUMAN
θ value	θ > 10 (rank : 871)	NC score	0.076762 (rank : 342)
Query Neighborhood Hits	455	Target Neighborhood Hits	1559	Shared Neighborhood Hits	150
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

REN3B_HUMAN
θ value	θ > 10 (rank : 872)	NC score	0.050131 (rank : 856)
Query Neighborhood Hits	455	Target Neighborhood Hits	412	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

RERE_HUMAN
θ value	θ > 10 (rank : 873)	NC score	0.061188 (rank : 630)
Query Neighborhood Hits	455	Target Neighborhood Hits	779	Shared Neighborhood Hits	103
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RERE_MOUSE
θ value	θ > 10 (rank : 874)	NC score	0.067750 (rank : 486)
Query Neighborhood Hits	455	Target Neighborhood Hits	785	Shared Neighborhood Hits	99
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

REST_HUMAN
θ value	θ > 10 (rank : 875)	NC score	0.075938 (rank : 357)
Query Neighborhood Hits	455	Target Neighborhood Hits	1605	Shared Neighborhood Hits	158
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

REST_MOUSE
θ value	θ > 10 (rank : 876)	NC score	0.074238 (rank : 383)
Query Neighborhood Hits	455	Target Neighborhood Hits	1506	Shared Neighborhood Hits	143
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

RFIP4_HUMAN
θ value	θ > 10 (rank : 877)	NC score	0.064374 (rank : 565)
Query Neighborhood Hits	455	Target Neighborhood Hits	785	Shared Neighborhood Hits	99
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

RFIP4_MOUSE
θ value	θ > 10 (rank : 878)	NC score	0.060225 (rank : 647)
Query Neighborhood Hits	455	Target Neighborhood Hits	708	Shared Neighborhood Hits	92
SwissProt Accessions	Q8BQP8, Q80T87	Gene names	Rab11fip4, Kiaa1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

RGNEF_MOUSE
θ value	θ > 10 (rank : 879)	NC score	0.064466 (rank : 564)
Query Neighborhood Hits	455	Target Neighborhood Hits	641	Shared Neighborhood Hits	99
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

RGS3_HUMAN
θ value	θ > 10 (rank : 880)	NC score	0.077503 (rank : 328)
Query Neighborhood Hits	455	Target Neighborhood Hits	1375	Shared Neighborhood Hits	174
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RHG04_HUMAN
θ value	θ > 10 (rank : 881)	NC score	0.060241 (rank : 646)
Query Neighborhood Hits	455	Target Neighborhood Hits	307	Shared Neighborhood Hits	80
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

RHG26_HUMAN
θ value	θ > 10 (rank : 882)	NC score	0.069011 (rank : 460)
Query Neighborhood Hits	455	Target Neighborhood Hits	281	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

RIMB1_HUMAN
θ value	θ > 10 (rank : 883)	NC score	0.125794 (rank : 103)
Query Neighborhood Hits	455	Target Neighborhood Hits	1479	Shared Neighborhood Hits	230
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RIMB2_HUMAN
θ value	θ > 10 (rank : 884)	NC score	0.089498 (rank : 221)
Query Neighborhood Hits	455	Target Neighborhood Hits	263	Shared Neighborhood Hits	68
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RIMB2_MOUSE
θ value	θ > 10 (rank : 885)	NC score	0.089379 (rank : 222)
Query Neighborhood Hits	455	Target Neighborhood Hits	246	Shared Neighborhood Hits	66
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

ROCK1_MOUSE
θ value	θ > 10 (rank : 886)	NC score	0.054931 (rank : 757)
Query Neighborhood Hits	455	Target Neighborhood Hits	2126	Shared Neighborhood Hits	153
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

ROCK2_MOUSE
θ value	θ > 10 (rank : 887)	NC score	0.050385 (rank : 853)
Query Neighborhood Hits	455	Target Neighborhood Hits	2072	Shared Neighborhood Hits	151
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

RPGR1_HUMAN
θ value	θ > 10 (rank : 888)	NC score	0.058566 (rank : 679)
Query Neighborhood Hits	455	Target Neighborhood Hits	578	Shared Neighborhood Hits	84
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

RRBP1_HUMAN
θ value	θ > 10 (rank : 889)	NC score	0.087296 (rank : 237)
Query Neighborhood Hits	455	Target Neighborhood Hits	1306	Shared Neighborhood Hits	152
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

RRBP1_MOUSE
θ value	θ > 10 (rank : 890)	NC score	0.089253 (rank : 223)
Query Neighborhood Hits	455	Target Neighborhood Hits	1650	Shared Neighborhood Hits	170
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

RTP3_MOUSE
θ value	θ > 10 (rank : 891)	NC score	0.059210 (rank : 668)
Query Neighborhood Hits	455	Target Neighborhood Hits	374	Shared Neighborhood Hits	79
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

RUFY1_HUMAN
θ value	θ > 10 (rank : 892)	NC score	0.053411 (rank : 791)
Query Neighborhood Hits	455	Target Neighborhood Hits	848	Shared Neighborhood Hits	94
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

RUFY2_HUMAN
θ value	θ > 10 (rank : 893)	NC score	0.066430 (rank : 516)
Query Neighborhood Hits	455	Target Neighborhood Hits	1208	Shared Neighborhood Hits	123
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

RUFY2_MOUSE
θ value	θ > 10 (rank : 894)	NC score	0.051251 (rank : 829)
Query Neighborhood Hits	455	Target Neighborhood Hits	820	Shared Neighborhood Hits	91
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

RUFY3_HUMAN
θ value	θ > 10 (rank : 895)	NC score	0.050958 (rank : 839)
Query Neighborhood Hits	455	Target Neighborhood Hits	594	Shared Neighborhood Hits	83
SwissProt Accessions	Q7L099, O94948, Q9UI00	Gene names	RUFY3, KIAA0871
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

RUFY3_MOUSE
θ value	θ > 10 (rank : 896)	NC score	0.050804 (rank : 842)
Query Neighborhood Hits	455	Target Neighborhood Hits	579	Shared Neighborhood Hits	83
SwissProt Accessions	Q9D394, Q3U348, Q3UF96, Q6PE64, Q8VD10	Gene names	Rufy3, D5Bwg0860e, Ripx
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

RUSC1_MOUSE
θ value	θ > 10 (rank : 897)	NC score	0.083907 (rank : 251)
Query Neighborhood Hits	455	Target Neighborhood Hits	206	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

SAS6_HUMAN
θ value	θ > 10 (rank : 898)	NC score	0.057614 (rank : 698)
Query Neighborhood Hits	455	Target Neighborhood Hits	791	Shared Neighborhood Hits	94
SwissProt Accessions	Q6UVJ0, Q8N3K0	Gene names	SASS6, SAS6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog (HsSAS-6).

SAS6_MOUSE
θ value	θ > 10 (rank : 899)	NC score	0.066390 (rank : 517)
Query Neighborhood Hits	455	Target Neighborhood Hits	931	Shared Neighborhood Hits	104
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

SC24C_HUMAN
θ value	θ > 10 (rank : 900)	NC score	0.057047 (rank : 710)
Query Neighborhood Hits	455	Target Neighborhood Hits	662	Shared Neighborhood Hits	89
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SDCG8_HUMAN
θ value	θ > 10 (rank : 901)	NC score	0.072920 (rank : 405)
Query Neighborhood Hits	455	Target Neighborhood Hits	1002	Shared Neighborhood Hits	117
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

SDCG8_MOUSE
θ value	θ > 10 (rank : 902)	NC score	0.063455 (rank : 588)
Query Neighborhood Hits	455	Target Neighborhood Hits	886	Shared Neighborhood Hits	112
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

SDPR_MOUSE
θ value	θ > 10 (rank : 903)	NC score	0.056574 (rank : 722)
Query Neighborhood Hits	455	Target Neighborhood Hits	485	Shared Neighborhood Hits	77
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

SELPL_HUMAN
θ value	θ > 10 (rank : 904)	NC score	0.081110 (rank : 277)
Query Neighborhood Hits	455	Target Neighborhood Hits	68	Shared Neighborhood Hits	17
SwissProt Accessions	Q14242, Q12775	Gene names	SELPLG
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand) (CD162 antigen).

SELV_HUMAN
θ value	θ > 10 (rank : 905)	NC score	0.063841 (rank : 582)
Query Neighborhood Hits	455	Target Neighborhood Hits	118	Shared Neighborhood Hits	35
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

SEPT9_HUMAN
θ value	θ > 10 (rank : 906)	NC score	0.058070 (rank : 686)
Query Neighborhood Hits	455	Target Neighborhood Hits	706	Shared Neighborhood Hits	133
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

SF3A2_HUMAN
θ value	θ > 10 (rank : 907)	NC score	0.055306 (rank : 750)
Query Neighborhood Hits	455	Target Neighborhood Hits	263	Shared Neighborhood Hits	44
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SF3A2_MOUSE
θ value	θ > 10 (rank : 908)	NC score	0.056379 (rank : 727)
Query Neighborhood Hits	455	Target Neighborhood Hits	247	Shared Neighborhood Hits	48
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SFPQ_HUMAN
θ value	θ > 10 (rank : 909)	NC score	0.063951 (rank : 579)
Query Neighborhood Hits	455	Target Neighborhood Hits	986	Shared Neighborhood Hits	126
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SFPQ_MOUSE
θ value	θ > 10 (rank : 910)	NC score	0.068804 (rank : 465)
Query Neighborhood Hits	455	Target Neighborhood Hits	958	Shared Neighborhood Hits	116
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SH3G2_HUMAN
θ value	θ > 10 (rank : 911)	NC score	0.151781 (rank : 60)
Query Neighborhood Hits	455	Target Neighborhood Hits	324	Shared Neighborhood Hits	99
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

SH3G2_MOUSE
θ value	θ > 10 (rank : 912)	NC score	0.150445 (rank : 63)
Query Neighborhood Hits	455	Target Neighborhood Hits	319	Shared Neighborhood Hits	102
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

SH3G3_HUMAN
θ value	θ > 10 (rank : 913)	NC score	0.141273 (rank : 71)
Query Neighborhood Hits	455	Target Neighborhood Hits	222	Shared Neighborhood Hits	84
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

SH3G3_MOUSE
θ value	θ > 10 (rank : 914)	NC score	0.148915 (rank : 64)
Query Neighborhood Hits	455	Target Neighborhood Hits	236	Shared Neighborhood Hits	85
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

SHAN2_MOUSE
θ value	θ > 10 (rank : 915)	NC score	0.070716 (rank : 434)
Query Neighborhood Hits	455	Target Neighborhood Hits	446	Shared Neighborhood Hits	91
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SKIL_MOUSE
θ value	θ > 10 (rank : 916)	NC score	0.053427 (rank : 790)
Query Neighborhood Hits	455	Target Neighborhood Hits	719	Shared Neighborhood Hits	103
SwissProt Accessions	Q60665, Q60702, Q78E90, Q80VK5	Gene names	Skil, Skir, Sno
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

SM1L2_HUMAN
θ value	θ > 10 (rank : 917)	NC score	0.083668 (rank : 254)
Query Neighborhood Hits	455	Target Neighborhood Hits	1019	Shared Neighborhood Hits	121
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

SMC3_HUMAN
θ value	θ > 10 (rank : 918)	NC score	0.074924 (rank : 374)
Query Neighborhood Hits	455	Target Neighborhood Hits	1186	Shared Neighborhood Hits	124
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	θ > 10 (rank : 919)	NC score	0.074954 (rank : 373)
Query Neighborhood Hits	455	Target Neighborhood Hits	1187	Shared Neighborhood Hits	124
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SMC4_HUMAN
θ value	θ > 10 (rank : 920)	NC score	0.070478 (rank : 440)
Query Neighborhood Hits	455	Target Neighborhood Hits	937	Shared Neighborhood Hits	112
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

SMC4_MOUSE
θ value	θ > 10 (rank : 921)	NC score	0.068139 (rank : 476)
Query Neighborhood Hits	455	Target Neighborhood Hits	830	Shared Neighborhood Hits	104
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

SNPC4_HUMAN
θ value	θ > 10 (rank : 922)	NC score	0.069745 (rank : 446)
Query Neighborhood Hits	455	Target Neighborhood Hits	589	Shared Neighborhood Hits	119
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

SNX18_HUMAN
θ value	θ > 10 (rank : 923)	NC score	0.082539 (rank : 260)
Query Neighborhood Hits	455	Target Neighborhood Hits	207	Shared Neighborhood Hits	67
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SNX18_MOUSE
θ value	θ > 10 (rank : 924)	NC score	0.081876 (rank : 270)
Query Neighborhood Hits	455	Target Neighborhood Hits	198	Shared Neighborhood Hits	65
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SNX9_HUMAN
θ value	θ > 10 (rank : 925)	NC score	0.054097 (rank : 773)
Query Neighborhood Hits	455	Target Neighborhood Hits	148	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y5X1, Q9BSI7, Q9BVM1, Q9UJH6, Q9UP20	Gene names	SNX9, SH3PX1
Domain Architecture
Description	Sorting nexin-9 (SH3 and PX domain-containing protein 1) (SDP1 protein).

SPAG5_MOUSE
θ value	θ > 10 (rank : 926)	NC score	0.052721 (rank : 806)
Query Neighborhood Hits	455	Target Neighborhood Hits	612	Shared Neighborhood Hits	87
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

SPN90_HUMAN
θ value	θ > 10 (rank : 927)	NC score	0.056472 (rank : 725)
Query Neighborhood Hits	455	Target Neighborhood Hits	157	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

SPN90_MOUSE
θ value	θ > 10 (rank : 928)	NC score	0.057901 (rank : 693)
Query Neighborhood Hits	455	Target Neighborhood Hits	157	Shared Neighborhood Hits	46
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

SPRR3_HUMAN
θ value	θ > 10 (rank : 929)	NC score	0.072408 (rank : 413)
Query Neighborhood Hits	455	Target Neighborhood Hits	102	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

SPRR3_MOUSE
θ value	θ > 10 (rank : 930)	NC score	0.060780 (rank : 635)
Query Neighborhood Hits	455	Target Neighborhood Hits	106	Shared Neighborhood Hits	28
SwissProt Accessions	O09116	Gene names	Sprr3
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta).

SPTA1_MOUSE
θ value	θ > 10 (rank : 931)	NC score	0.076854 (rank : 338)
Query Neighborhood Hits	455	Target Neighborhood Hits	675	Shared Neighborhood Hits	132
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SPTA2_HUMAN
θ value	θ > 10 (rank : 932)	NC score	0.107484 (rank : 144)
Query Neighborhood Hits	455	Target Neighborhood Hits	888	Shared Neighborhood Hits	158
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

SRC8_MOUSE
θ value	θ > 10 (rank : 933)	NC score	0.179026 (rank : 42)
Query Neighborhood Hits	455	Target Neighborhood Hits	292	Shared Neighborhood Hits	94
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

SRGP1_HUMAN
θ value	θ > 10 (rank : 934)	NC score	0.051195 (rank : 834)
Query Neighborhood Hits	455	Target Neighborhood Hits	390	Shared Neighborhood Hits	91
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

SRGP2_HUMAN
θ value	θ > 10 (rank : 935)	NC score	0.052402 (rank : 810)
Query Neighborhood Hits	455	Target Neighborhood Hits	331	Shared Neighborhood Hits	81
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

SRGP2_MOUSE
θ value	θ > 10 (rank : 936)	NC score	0.052869 (rank : 802)
Query Neighborhood Hits	455	Target Neighborhood Hits	324	Shared Neighborhood Hits	85
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

SRRM1_HUMAN
θ value	θ > 10 (rank : 937)	NC score	0.090199 (rank : 215)
Query Neighborhood Hits	455	Target Neighborhood Hits	690	Shared Neighborhood Hits	87
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM2_HUMAN
θ value	θ > 10 (rank : 938)	NC score	0.074187 (rank : 384)
Query Neighborhood Hits	455	Target Neighborhood Hits	1296	Shared Neighborhood Hits	146
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
θ value	θ > 10 (rank : 939)	NC score	0.082471 (rank : 261)
Query Neighborhood Hits	455	Target Neighborhood Hits	1470	Shared Neighborhood Hits	168
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

STAC3_HUMAN
θ value	θ > 10 (rank : 940)	NC score	0.116982 (rank : 125)
Query Neighborhood Hits	455	Target Neighborhood Hits	228	Shared Neighborhood Hits	70
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	θ > 10 (rank : 941)	NC score	0.117719 (rank : 122)
Query Neighborhood Hits	455	Target Neighborhood Hits	232	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC_HUMAN
θ value	θ > 10 (rank : 942)	NC score	0.128832 (rank : 97)
Query Neighborhood Hits	455	Target Neighborhood Hits	276	Shared Neighborhood Hits	80
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAC_MOUSE
θ value	θ > 10 (rank : 943)	NC score	0.124901 (rank : 109)
Query Neighborhood Hits	455	Target Neighborhood Hits	268	Shared Neighborhood Hits	81
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STIM1_HUMAN
θ value	θ > 10 (rank : 944)	NC score	0.054008 (rank : 774)
Query Neighborhood Hits	455	Target Neighborhood Hits	665	Shared Neighborhood Hits	102
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

STIM1_MOUSE
θ value	θ > 10 (rank : 945)	NC score	0.053803 (rank : 781)
Query Neighborhood Hits	455	Target Neighborhood Hits	660	Shared Neighborhood Hits	101
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

SWP70_HUMAN
θ value	θ > 10 (rank : 946)	NC score	0.064670 (rank : 556)
Query Neighborhood Hits	455	Target Neighborhood Hits	973	Shared Neighborhood Hits	112
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_MOUSE
θ value	θ > 10 (rank : 947)	NC score	0.065530 (rank : 538)
Query Neighborhood Hits	455	Target Neighborhood Hits	1097	Shared Neighborhood Hits	124
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SYN1_HUMAN
θ value	θ > 10 (rank : 948)	NC score	0.052878 (rank : 801)
Query Neighborhood Hits	455	Target Neighborhood Hits	419	Shared Neighborhood Hits	64
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

SYNE1_HUMAN
θ value	θ > 10 (rank : 949)	NC score	0.065627 (rank : 536)
Query Neighborhood Hits	455	Target Neighborhood Hits	1484	Shared Neighborhood Hits	130
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

T22D2_HUMAN
θ value	θ > 10 (rank : 950)	NC score	0.053408 (rank : 792)
Query Neighborhood Hits	455	Target Neighborhood Hits	250	Shared Neighborhood Hits	44
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

T3JAM_HUMAN
θ value	θ > 10 (rank : 951)	NC score	0.053899 (rank : 777)
Query Neighborhood Hits	455	Target Neighborhood Hits	533	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

TACC1_HUMAN
θ value	θ > 10 (rank : 952)	NC score	0.068501 (rank : 467)
Query Neighborhood Hits	455	Target Neighborhood Hits	597	Shared Neighborhood Hits	93
SwissProt Accessions	O75410, Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2, Q8NEY7, Q9UPP9	Gene names	TACC1, KIAA1103
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 1 (Taxin 1) (Gastric cancer antigen Ga55).

TACC1_MOUSE
θ value	θ > 10 (rank : 953)	NC score	0.076394 (rank : 353)
Query Neighborhood Hits	455	Target Neighborhood Hits	667	Shared Neighborhood Hits	111
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

TACC3_HUMAN
θ value	θ > 10 (rank : 954)	NC score	0.088070 (rank : 234)
Query Neighborhood Hits	455	Target Neighborhood Hits	779	Shared Neighborhood Hits	131
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

TACC3_MOUSE
θ value	θ > 10 (rank : 955)	NC score	0.073335 (rank : 397)
Query Neighborhood Hits	455	Target Neighborhood Hits	607	Shared Neighborhood Hits	95
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

TAF3_HUMAN
θ value	θ > 10 (rank : 956)	NC score	0.064092 (rank : 575)
Query Neighborhood Hits	455	Target Neighborhood Hits	568	Shared Neighborhood Hits	95
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TAF3_MOUSE
θ value	θ > 10 (rank : 957)	NC score	0.057478 (rank : 701)
Query Neighborhood Hits	455	Target Neighborhood Hits	463	Shared Neighborhood Hits	77
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TAF4_HUMAN
θ value	θ > 10 (rank : 958)	NC score	0.103745 (rank : 155)
Query Neighborhood Hits	455	Target Neighborhood Hits	687	Shared Neighborhood Hits	98
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TARA_HUMAN
θ value	θ > 10 (rank : 959)	NC score	0.094450 (rank : 194)
Query Neighborhood Hits	455	Target Neighborhood Hits	1626	Shared Neighborhood Hits	209
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TARA_MOUSE
θ value	θ > 10 (rank : 960)	NC score	0.077777 (rank : 325)
Query Neighborhood Hits	455	Target Neighborhood Hits	1133	Shared Neighborhood Hits	161
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TAXB1_HUMAN
θ value	θ > 10 (rank : 961)	NC score	0.069695 (rank : 447)
Query Neighborhood Hits	455	Target Neighborhood Hits	829	Shared Neighborhood Hits	92
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

TAXB1_MOUSE
θ value	θ > 10 (rank : 962)	NC score	0.072744 (rank : 410)
Query Neighborhood Hits	455	Target Neighborhood Hits	886	Shared Neighborhood Hits	105
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

TCAL5_HUMAN
θ value	θ > 10 (rank : 963)	NC score	0.051205 (rank : 833)
Query Neighborhood Hits	455	Target Neighborhood Hits	806	Shared Neighborhood Hits	89
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TCGAP_HUMAN
θ value	θ > 10 (rank : 964)	NC score	0.079355 (rank : 306)
Query Neighborhood Hits	455	Target Neighborhood Hits	872	Shared Neighborhood Hits	141
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCGAP_MOUSE
θ value	θ > 10 (rank : 965)	NC score	0.065744 (rank : 533)
Query Neighborhood Hits	455	Target Neighborhood Hits	409	Shared Neighborhood Hits	101
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCRG1_HUMAN
θ value	θ > 10 (rank : 966)	NC score	0.080866 (rank : 281)
Query Neighborhood Hits	455	Target Neighborhood Hits	929	Shared Neighborhood Hits	128
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	θ > 10 (rank : 967)	NC score	0.081969 (rank : 267)
Query Neighborhood Hits	455	Target Neighborhood Hits	947	Shared Neighborhood Hits	131
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TEX9_HUMAN
θ value	θ > 10 (rank : 968)	NC score	0.057220 (rank : 703)
Query Neighborhood Hits	455	Target Neighborhood Hits	541	Shared Neighborhood Hits	78
SwissProt Accessions	Q8N6V9	Gene names	TEX9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein.

TEX9_MOUSE
θ value	θ > 10 (rank : 969)	NC score	0.059022 (rank : 671)
Query Neighborhood Hits	455	Target Neighborhood Hits	581	Shared Neighborhood Hits	84
SwissProt Accessions	Q9D845, O54764	Gene names	Tex9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1).

TGON2_HUMAN
θ value	θ > 10 (rank : 970)	NC score	0.099143 (rank : 173)
Query Neighborhood Hits	455	Target Neighborhood Hits	1037	Shared Neighborhood Hits	151
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TM108_MOUSE
θ value	θ > 10 (rank : 971)	NC score	0.055832 (rank : 737)
Query Neighborhood Hits	455	Target Neighborhood Hits	336	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TMAP1_HUMAN
θ value	θ > 10 (rank : 972)	NC score	0.114124 (rank : 131)
Query Neighborhood Hits	455	Target Neighborhood Hits	140	Shared Neighborhood Hits	37
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

TMF1_HUMAN
θ value	θ > 10 (rank : 973)	NC score	0.076622 (rank : 347)
Query Neighborhood Hits	455	Target Neighborhood Hits	987	Shared Neighborhood Hits	122
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

TNIP3_HUMAN
θ value	θ > 10 (rank : 974)	NC score	0.057491 (rank : 700)
Query Neighborhood Hits	455	Target Neighborhood Hits	511	Shared Neighborhood Hits	73
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

TP53B_HUMAN
θ value	θ > 10 (rank : 975)	NC score	0.053365 (rank : 794)
Query Neighborhood Hits	455	Target Neighborhood Hits	413	Shared Neighborhood Hits	73
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TP53B_MOUSE
θ value	θ > 10 (rank : 976)	NC score	0.081916 (rank : 269)
Query Neighborhood Hits	455	Target Neighborhood Hits	644	Shared Neighborhood Hits	118
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TPM1_HUMAN
θ value	θ > 10 (rank : 977)	NC score	0.075767 (rank : 362)
Query Neighborhood Hits	455	Target Neighborhood Hits	716	Shared Neighborhood Hits	97
SwissProt Accessions	P09493, P09494, P10469, Q86W64, Q96IK2, Q9UCY9	Gene names	TPM1, TMSA
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

TPM1_MOUSE
θ value	θ > 10 (rank : 978)	NC score	0.075889 (rank : 358)
Query Neighborhood Hits	455	Target Neighborhood Hits	729	Shared Neighborhood Hits	99
SwissProt Accessions	P58771, P02558, P19354, P46902, P99034	Gene names	Tpm1, Tpm-1, Tpma
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

TPM3_HUMAN
θ value	θ > 10 (rank : 979)	NC score	0.067590 (rank : 489)
Query Neighborhood Hits	455	Target Neighborhood Hits	689	Shared Neighborhood Hits	84
SwissProt Accessions	P06753, P12324, Q969Q2, Q9NQH8	Gene names	TPM3
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma) (hTM5).

TPM3_MOUSE
θ value	θ > 10 (rank : 980)	NC score	0.067277 (rank : 494)
Query Neighborhood Hits	455	Target Neighborhood Hits	676	Shared Neighborhood Hits	85
SwissProt Accessions	P21107, Q09021, Q60606, Q80SW6, Q9EPW3	Gene names	Tpm3, Tpm-5, Tpm5
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma).

TPM4_HUMAN
θ value	θ > 10 (rank : 981)	NC score	0.063437 (rank : 589)
Query Neighborhood Hits	455	Target Neighborhood Hits	525	Shared Neighborhood Hits	79
SwissProt Accessions	P67936, P07226, Q15659, Q9BU85, Q9H8Q3	Gene names	TPM4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4) (TM30p1).

TPM4_MOUSE
θ value	θ > 10 (rank : 982)	NC score	0.072996 (rank : 403)
Query Neighborhood Hits	455	Target Neighborhood Hits	703	Shared Neighborhood Hits	97
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

TRAIP_HUMAN
θ value	θ > 10 (rank : 983)	NC score	0.059656 (rank : 661)
Query Neighborhood Hits	455	Target Neighborhood Hits	780	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
θ value	θ > 10 (rank : 984)	NC score	0.056130 (rank : 732)
Query Neighborhood Hits	455	Target Neighborhood Hits	745	Shared Neighborhood Hits	89
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

TRAK1_HUMAN
θ value	θ > 10 (rank : 985)	NC score	0.061364 (rank : 627)
Query Neighborhood Hits	455	Target Neighborhood Hits	660	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

TRDN_HUMAN
θ value	θ > 10 (rank : 986)	NC score	0.059366 (rank : 665)
Query Neighborhood Hits	455	Target Neighborhood Hits	542	Shared Neighborhood Hits	68
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TRIPB_HUMAN
θ value	θ > 10 (rank : 987)	NC score	0.080060 (rank : 289)
Query Neighborhood Hits	455	Target Neighborhood Hits	1587	Shared Neighborhood Hits	148
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

TROAP_HUMAN
θ value	θ > 10 (rank : 988)	NC score	0.051891 (rank : 815)
Query Neighborhood Hits	455	Target Neighborhood Hits	258	Shared Neighborhood Hits	50
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

TSC1_HUMAN
θ value	θ > 10 (rank : 989)	NC score	0.066860 (rank : 500)
Query Neighborhood Hits	455	Target Neighborhood Hits	765	Shared Neighborhood Hits	117
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

TUFT1_HUMAN
θ value	θ > 10 (rank : 990)	NC score	0.066777 (rank : 502)
Query Neighborhood Hits	455	Target Neighborhood Hits	686	Shared Neighborhood Hits	96
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

TUFT1_MOUSE
θ value	θ > 10 (rank : 991)	NC score	0.064948 (rank : 554)
Query Neighborhood Hits	455	Target Neighborhood Hits	732	Shared Neighborhood Hits	98
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

TXLNA_MOUSE
θ value	θ > 10 (rank : 992)	NC score	0.068314 (rank : 474)
Query Neighborhood Hits	455	Target Neighborhood Hits	846	Shared Neighborhood Hits	111
SwissProt Accessions	Q6PAM1, Q6P1E5	Gene names	Txlna, Txln
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

TXLNB_MOUSE
θ value	θ > 10 (rank : 993)	NC score	0.057897 (rank : 694)
Query Neighborhood Hits	455	Target Neighborhood Hits	640	Shared Neighborhood Hits	94
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

TXLNG_HUMAN
θ value	θ > 10 (rank : 994)	NC score	0.056125 (rank : 733)
Query Neighborhood Hits	455	Target Neighborhood Hits	568	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NUQ3, Q9P0X1	Gene names	TXLNG, CXorf15, LSR5
Domain Architecture	No domain graphic available
Description	Gamma-taxilin (Lipopolysaccharide-specific response protein 5).

TXLNG_MOUSE
θ value	θ > 10 (rank : 995)	NC score	0.053941 (rank : 776)
Query Neighborhood Hits	455	Target Neighborhood Hits	552	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BHN1, Q8BP11	Gene names	Txlng
Domain Architecture	No domain graphic available
Description	Gamma-taxilin.

TXND2_HUMAN
θ value	θ > 10 (rank : 996)	NC score	0.144358 (rank : 68)
Query Neighborhood Hits	455	Target Neighborhood Hits	793	Shared Neighborhood Hits	140
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

TXND2_MOUSE
θ value	θ > 10 (rank : 997)	NC score	0.069665 (rank : 448)
Query Neighborhood Hits	455	Target Neighborhood Hits	828	Shared Neighborhood Hits	112
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

UACA_HUMAN
θ value	θ > 10 (rank : 998)	NC score	0.066682 (rank : 504)
Query Neighborhood Hits	455	Target Neighborhood Hits	1622	Shared Neighborhood Hits	142
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

UACA_MOUSE
θ value	θ > 10 (rank : 999)	NC score	0.064654 (rank : 558)
Query Neighborhood Hits	455	Target Neighborhood Hits	1620	Shared Neighborhood Hits	136
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

UTRO_HUMAN
θ value	θ > 10 (rank : 1000)	NC score	0.051161 (rank : 835)
Query Neighborhood Hits	455	Target Neighborhood Hits	960	Shared Neighborhood Hits	102
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

VAV2_HUMAN
θ value	θ > 10 (rank : 1001)	NC score	0.097417 (rank : 180)
Query Neighborhood Hits	455	Target Neighborhood Hits	453	Shared Neighborhood Hits	88
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
θ value	θ > 10 (rank : 1002)	NC score	0.097366 (rank : 181)
Query Neighborhood Hits	455	Target Neighborhood Hits	456	Shared Neighborhood Hits	88
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

VAV3_HUMAN
θ value	θ > 10 (rank : 1003)	NC score	0.078501 (rank : 316)
Query Neighborhood Hits	455	Target Neighborhood Hits	398	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV3_MOUSE
θ value	θ > 10 (rank : 1004)	NC score	0.077845 (rank : 324)
Query Neighborhood Hits	455	Target Neighborhood Hits	404	Shared Neighborhood Hits	84
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

VAV_HUMAN
θ value	θ > 10 (rank : 1005)	NC score	0.104420 (rank : 153)
Query Neighborhood Hits	455	Target Neighborhood Hits	452	Shared Neighborhood Hits	100
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

VAV_MOUSE
θ value	θ > 10 (rank : 1006)	NC score	0.104256 (rank : 154)
Query Neighborhood Hits	455	Target Neighborhood Hits	430	Shared Neighborhood Hits	91
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

VCX1_HUMAN
θ value	θ > 10 (rank : 1007)	NC score	0.063689 (rank : 583)
Query Neighborhood Hits	455	Target Neighborhood Hits	129	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

VCX3_HUMAN
θ value	θ > 10 (rank : 1008)	NC score	0.066651 (rank : 506)
Query Neighborhood Hits	455	Target Neighborhood Hits	105	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

VCXC_HUMAN
θ value	θ > 10 (rank : 1009)	NC score	0.066195 (rank : 520)
Query Neighborhood Hits	455	Target Neighborhood Hits	139	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

VDP_HUMAN
θ value	θ > 10 (rank : 1010)	NC score	0.053854 (rank : 779)
Query Neighborhood Hits	455	Target Neighborhood Hits	645	Shared Neighborhood Hits	85
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

VIME_MOUSE
θ value	θ > 10 (rank : 1011)	NC score	0.051098 (rank : 836)
Query Neighborhood Hits	455	Target Neighborhood Hits	716	Shared Neighborhood Hits	99
SwissProt Accessions	P20152, O08704, Q8CCH1	Gene names	Vim
Domain Architecture
Description	Vimentin.

WASIP_HUMAN
θ value	θ > 10 (rank : 1012)	NC score	0.078279 (rank : 320)
Query Neighborhood Hits	455	Target Neighborhood Hits	458	Shared Neighborhood Hits	69
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WASIP_MOUSE
θ value	θ > 10 (rank : 1013)	NC score	0.071757 (rank : 422)
Query Neighborhood Hits	455	Target Neighborhood Hits	392	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

WBP11_HUMAN
θ value	θ > 10 (rank : 1014)	NC score	0.060383 (rank : 644)
Query Neighborhood Hits	455	Target Neighborhood Hits	354	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
θ value	θ > 10 (rank : 1015)	NC score	0.055738 (rank : 739)
Query Neighborhood Hits	455	Target Neighborhood Hits	362	Shared Neighborhood Hits	61
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

WDR67_HUMAN
θ value	θ > 10 (rank : 1016)	NC score	0.053351 (rank : 795)
Query Neighborhood Hits	455	Target Neighborhood Hits	782	Shared Neighborhood Hits	85
SwissProt Accessions	Q96DN5, Q3MIR6, Q8TBP9	Gene names	WDR67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67.

XE7_HUMAN
θ value	θ > 10 (rank : 1017)	NC score	0.064559 (rank : 561)
Query Neighborhood Hits	455	Target Neighborhood Hits	738	Shared Neighborhood Hits	90
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

YLPM1_HUMAN
θ value	θ > 10 (rank : 1018)	NC score	0.062839 (rank : 602)
Query Neighborhood Hits	455	Target Neighborhood Hits	670	Shared Neighborhood Hits	97
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

YLPM1_MOUSE
θ value	θ > 10 (rank : 1019)	NC score	0.056905 (rank : 713)
Query Neighborhood Hits	455	Target Neighborhood Hits	505	Shared Neighborhood Hits	73
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ZC313_HUMAN
θ value	θ > 10 (rank : 1020)	NC score	0.057595 (rank : 699)
Query Neighborhood Hits	455	Target Neighborhood Hits	772	Shared Neighborhood Hits	95
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

ZN207_HUMAN
θ value	θ > 10 (rank : 1021)	NC score	0.061566 (rank : 620)
Query Neighborhood Hits	455	Target Neighborhood Hits	326	Shared Neighborhood Hits	40
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

ZN291_HUMAN
θ value	θ > 10 (rank : 1022)	NC score	0.059734 (rank : 660)
Query Neighborhood Hits	455	Target Neighborhood Hits	647	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

ZN318_MOUSE
θ value	θ > 10 (rank : 1023)	NC score	0.054191 (rank : 769)
Query Neighborhood Hits	455	Target Neighborhood Hits	642	Shared Neighborhood Hits	95
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

ZN750_MOUSE
θ value	θ > 10 (rank : 1024)	NC score	0.050725 (rank : 847)
Query Neighborhood Hits	455	Target Neighborhood Hits	346	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

ZWINT_MOUSE
θ value	θ > 10 (rank : 1025)	NC score	0.060139 (rank : 654)
Query Neighborhood Hits	455	Target Neighborhood Hits	497	Shared Neighborhood Hits	81
SwissProt Accessions	Q9CQU5, Q3UYT8, Q91VI4, Q9D0W9	Gene names	Zwint, D10Ertd749e
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

Hits sorted by NC score

AMPH_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	455	Target Neighborhood Hits	455	Shared Neighborhood Hits	455
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

AMPH_MOUSE
NC score	0.926014 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	455	Target Neighborhood Hits	291	Shared Neighborhood Hits	224
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

BIN1_MOUSE
NC score	0.823478 (rank : 3)	θ value	3.09092e-117 (rank : 4)
Query Neighborhood Hits	455	Target Neighborhood Hits	283	Shared Neighborhood Hits	105
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

BIN1_HUMAN
NC score	0.822528 (rank : 4)	θ value	1.06234e-117 (rank : 3)
Query Neighborhood Hits	455	Target Neighborhood Hits	335	Shared Neighborhood Hits	119
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

BIN3_MOUSE
NC score	0.340014 (rank : 5)	θ value	4.45536e-07 (rank : 6)
Query Neighborhood Hits	455	Target Neighborhood Hits	165	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JI08	Gene names	Bin3
Domain Architecture	No domain graphic available
Description	Bridging integrator 3.

BIN3_HUMAN
NC score	0.339596 (rank : 6)	θ value	2.88788e-06 (rank : 7)
Query Neighborhood Hits	455	Target Neighborhood Hits	95	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NQY0, Q9BVG2, Q9NVY9	Gene names	BIN3
Domain Architecture
Description	Bridging integrator 3.

ABI2_HUMAN
NC score	0.266749 (rank : 7)	θ value	0.000158464 (rank : 14)
Query Neighborhood Hits	455	Target Neighborhood Hits	350	Shared Neighborhood Hits	111
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

DNMBP_HUMAN
NC score	0.260551 (rank : 8)	θ value	1.99992e-07 (rank : 5)
Query Neighborhood Hits	455	Target Neighborhood Hits	413	Shared Neighborhood Hits	112
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

ABI2_MOUSE
NC score	0.257524 (rank : 9)	θ value	0.000158464 (rank : 15)
Query Neighborhood Hits	455	Target Neighborhood Hits	266	Shared Neighborhood Hits	91
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

SH3K1_HUMAN
NC score	0.255972 (rank : 10)	θ value	0.00509761 (rank : 34)
Query Neighborhood Hits	455	Target Neighborhood Hits	341	Shared Neighborhood Hits	105
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

ABI1_MOUSE
NC score	0.253893 (rank : 11)	θ value	0.0148317 (rank : 47)
Query Neighborhood Hits	455	Target Neighborhood Hits	246	Shared Neighborhood Hits	93
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

SH3K1_MOUSE
NC score	0.252257 (rank : 12)	θ value	0.00509761 (rank : 35)
Query Neighborhood Hits	455	Target Neighborhood Hits	332	Shared Neighborhood Hits	106
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

DNMBP_MOUSE
NC score	0.248888 (rank : 13)	θ value	1.43324e-05 (rank : 9)
Query Neighborhood Hits	455	Target Neighborhood Hits	435	Shared Neighborhood Hits	117
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

ABI1_HUMAN
NC score	0.245997 (rank : 14)	θ value	0.0563607 (rank : 67)
Query Neighborhood Hits	455	Target Neighborhood Hits	257	Shared Neighborhood Hits	95
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

CD2AP_MOUSE
NC score	0.245600 (rank : 15)	θ value	0.0736092 (rank : 76)
Query Neighborhood Hits	455	Target Neighborhood Hits	336	Shared Neighborhood Hits	113
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

CD2AP_HUMAN
NC score	0.243385 (rank : 16)	θ value	0.0736092 (rank : 75)
Query Neighborhood Hits	455	Target Neighborhood Hits	315	Shared Neighborhood Hits	105
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

STAM1_MOUSE
NC score	0.229642 (rank : 17)	θ value	0.000786445 (rank : 19)
Query Neighborhood Hits	455	Target Neighborhood Hits	273	Shared Neighborhood Hits	88
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM1_HUMAN
NC score	0.219818 (rank : 18)	θ value	0.00665767 (rank : 38)
Query Neighborhood Hits	455	Target Neighborhood Hits	271	Shared Neighborhood Hits	87
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM2_HUMAN
NC score	0.214437 (rank : 19)	θ value	0.00390308 (rank : 32)
Query Neighborhood Hits	455	Target Neighborhood Hits	288	Shared Neighborhood Hits	89
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

LASP1_MOUSE
NC score	0.213230 (rank : 20)	θ value	0.0193708 (rank : 53)
Query Neighborhood Hits	455	Target Neighborhood Hits	297	Shared Neighborhood Hits	85
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

LASP1_HUMAN
NC score	0.212922 (rank : 21)	θ value	0.00298849 (rank : 28)
Query Neighborhood Hits	455	Target Neighborhood Hits	293	Shared Neighborhood Hits	84
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

SRBS1_HUMAN
NC score	0.212510 (rank : 22)	θ value	2.36792 (rank : 256)
Query Neighborhood Hits	455	Target Neighborhood Hits	396	Shared Neighborhood Hits	113
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

NACAM_MOUSE
NC score	0.210313 (rank : 23)	θ value	3.19293e-05 (rank : 11)
Query Neighborhood Hits	455	Target Neighborhood Hits	1866	Shared Neighborhood Hits	221
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

CN155_HUMAN
NC score	0.210200 (rank : 24)	θ value	8.40245e-06 (rank : 8)
Query Neighborhood Hits	455	Target Neighborhood Hits	385	Shared Neighborhood Hits	89
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

HCLS1_MOUSE
NC score	0.204309 (rank : 25)	θ value	0.0252991 (rank : 55)
Query Neighborhood Hits	455	Target Neighborhood Hits	329	Shared Neighborhood Hits	119
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

ABI3_MOUSE
NC score	0.203813 (rank : 26)	θ value	0.00869519 (rank : 39)
Query Neighborhood Hits	455	Target Neighborhood Hits	227	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

HCLS1_HUMAN
NC score	0.200888 (rank : 27)	θ value	0.0961366 (rank : 84)
Query Neighborhood Hits	455	Target Neighborhood Hits	358	Shared Neighborhood Hits	122
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

VINEX_HUMAN
NC score	0.199592 (rank : 28)	θ value	0.0736092 (rank : 82)
Query Neighborhood Hits	455	Target Neighborhood Hits	270	Shared Neighborhood Hits	93
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

NCF2_HUMAN
NC score	0.199056 (rank : 29)	θ value	5.27518 (rank : 346)
Query Neighborhood Hits	455	Target Neighborhood Hits	229	Shared Neighborhood Hits	80
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

STS2_HUMAN
NC score	0.198486 (rank : 30)	θ value	0.0113563 (rank : 46)
Query Neighborhood Hits	455	Target Neighborhood Hits	108	Shared Neighborhood Hits	57
SwissProt Accessions	P57075, Q6HA34, Q6HA35, Q6ISI6, Q6ISK3, Q6ISS9	Gene names	UBASH3A, STS2
Domain Architecture
Description	Suppressor of T-cell receptor signaling 2 (STS-2) (Cbl-interacting protein 4) (CLIP4) (T-cell ubiquitin ligand) (TULA).

PACN2_MOUSE
NC score	0.197142 (rank : 31)	θ value	1.38821 (rank : 207)
Query Neighborhood Hits	455	Target Neighborhood Hits	382	Shared Neighborhood Hits	114
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

STAM2_MOUSE
NC score	0.196606 (rank : 32)	θ value	0.0330416 (rank : 61)
Query Neighborhood Hits	455	Target Neighborhood Hits	285	Shared Neighborhood Hits	87
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

SRBS1_MOUSE
NC score	0.195697 (rank : 33)	θ value	2.36792 (rank : 257)
Query Neighborhood Hits	455	Target Neighborhood Hits	409	Shared Neighborhood Hits	117
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRC8_HUMAN
NC score	0.190223 (rank : 34)	θ value	2.36792 (rank : 258)
Query Neighborhood Hits	455	Target Neighborhood Hits	269	Shared Neighborhood Hits	85
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

ITSN1_MOUSE
NC score	0.189294 (rank : 35)	θ value	0.00869519 (rank : 41)
Query Neighborhood Hits	455	Target Neighborhood Hits	1669	Shared Neighborhood Hits	236
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ITSN1_HUMAN
NC score	0.188531 (rank : 36)	θ value	0.0148317 (rank : 49)
Query Neighborhood Hits	455	Target Neighborhood Hits	1757	Shared Neighborhood Hits	244
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

PPIP1_MOUSE
NC score	0.186648 (rank : 37)	θ value	1.38821 (rank : 209)
Query Neighborhood Hits	455	Target Neighborhood Hits	377	Shared Neighborhood Hits	118
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

PACN2_HUMAN
NC score	0.184266 (rank : 38)	θ value	1.38821 (rank : 206)
Query Neighborhood Hits	455	Target Neighborhood Hits	339	Shared Neighborhood Hits	107
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

VINEX_MOUSE
NC score	0.184044 (rank : 39)	θ value	5.27518 (rank : 364)
Query Neighborhood Hits	455	Target Neighborhood Hits	286	Shared Neighborhood Hits	93
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

PACN3_MOUSE
NC score	0.182360 (rank : 40)	θ value	0.0736092 (rank : 81)
Query Neighborhood Hits	455	Target Neighborhood Hits	380	Shared Neighborhood Hits	109
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

PACN3_HUMAN
NC score	0.179578 (rank : 41)	θ value	0.279714 (rank : 118)
Query Neighborhood Hits	455	Target Neighborhood Hits	385	Shared Neighborhood Hits	109
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

SRC8_MOUSE
NC score	0.179026 (rank : 42)	θ value	θ > 10 (rank : 933)
Query Neighborhood Hits	455	Target Neighborhood Hits	292	Shared Neighborhood Hits	94
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

ABI3_HUMAN
NC score	0.177525 (rank : 43)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	455	Target Neighborhood Hits	227	Shared Neighborhood Hits	86
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

PACN1_MOUSE
NC score	0.176617 (rank : 44)	θ value	6.88961 (rank : 399)
Query Neighborhood Hits	455	Target Neighborhood Hits	283	Shared Neighborhood Hits	100
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

ITSN2_HUMAN
NC score	0.176522 (rank : 45)	θ value	0.279714 (rank : 115)
Query Neighborhood Hits	455	Target Neighborhood Hits	1173	Shared Neighborhood Hits	183
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

MARCS_HUMAN
NC score	0.175324 (rank : 46)	θ value	0.0563607 (rank : 71)
Query Neighborhood Hits	455	Target Neighborhood Hits	204	Shared Neighborhood Hits	51
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

PACN1_HUMAN
NC score	0.174513 (rank : 47)	θ value	6.88961 (rank : 398)
Query Neighborhood Hits	455	Target Neighborhood Hits	320	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PPIP1_HUMAN
NC score	0.173912 (rank : 48)	θ value	6.88961 (rank : 402)
Query Neighborhood Hits	455	Target Neighborhood Hits	389	Shared Neighborhood Hits	118
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

SELPL_MOUSE
NC score	0.172783 (rank : 49)	θ value	0.163984 (rank : 102)
Query Neighborhood Hits	455	Target Neighborhood Hits	588	Shared Neighborhood Hits	134
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

ITSN2_MOUSE
NC score	0.171694 (rank : 50)	θ value	0.0961366 (rank : 85)
Query Neighborhood Hits	455	Target Neighborhood Hits	1371	Shared Neighborhood Hits	192
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

MARCS_MOUSE
NC score	0.169099 (rank : 51)	θ value	0.00102713 (rank : 20)
Query Neighborhood Hits	455	Target Neighborhood Hits	227	Shared Neighborhood Hits	49
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MDC1_HUMAN
NC score	0.165192 (rank : 52)	θ value	0.0736092 (rank : 78)
Query Neighborhood Hits	455	Target Neighborhood Hits	1446	Shared Neighborhood Hits	221
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

SON_HUMAN
NC score	0.162902 (rank : 53)	θ value	0.00035302 (rank : 17)
Query Neighborhood Hits	455	Target Neighborhood Hits	1568	Shared Neighborhood Hits	186
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

NEBL_HUMAN
NC score	0.162785 (rank : 54)	θ value	θ > 10 (rank : 803)
Query Neighborhood Hits	455	Target Neighborhood Hits	457	Shared Neighborhood Hits	130
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

OGFR_HUMAN
NC score	0.160431 (rank : 55)	θ value	0.00665767 (rank : 37)
Query Neighborhood Hits	455	Target Neighborhood Hits	1582	Shared Neighborhood Hits	199
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

SH3G1_HUMAN
NC score	0.156875 (rank : 56)	θ value	0.62314 (rank : 153)
Query Neighborhood Hits	455	Target Neighborhood Hits	307	Shared Neighborhood Hits	105
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

BASP_MOUSE
NC score	0.155750 (rank : 57)	θ value	0.0736092 (rank : 74)
Query Neighborhood Hits	455	Target Neighborhood Hits	260	Shared Neighborhood Hits	56
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

NCK1_HUMAN
NC score	0.153075 (rank : 58)	θ value	0.62314 (rank : 150)
Query Neighborhood Hits	455	Target Neighborhood Hits	312	Shared Neighborhood Hits	87
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

SH3G1_MOUSE
NC score	0.152682 (rank : 59)	θ value	1.81305 (rank : 228)
Query Neighborhood Hits	455	Target Neighborhood Hits	291	Shared Neighborhood Hits	99
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

SH3G2_HUMAN
NC score	0.151781 (rank : 60)	θ value	θ > 10 (rank : 911)
Query Neighborhood Hits	455	Target Neighborhood Hits	324	Shared Neighborhood Hits	99
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

ARHG6_MOUSE
NC score	0.151395 (rank : 61)	θ value	0.47712 (rank : 130)
Query Neighborhood Hits	455	Target Neighborhood Hits	394	Shared Neighborhood Hits	107
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

ARHG6_HUMAN
NC score	0.150532 (rank : 62)	θ value	1.06291 (rank : 176)
Query Neighborhood Hits	455	Target Neighborhood Hits	376	Shared Neighborhood Hits	111
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

SH3G2_MOUSE
NC score	0.150445 (rank : 63)	θ value	θ > 10 (rank : 912)
Query Neighborhood Hits	455	Target Neighborhood Hits	319	Shared Neighborhood Hits	102
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

SH3G3_MOUSE
NC score	0.148915 (rank : 64)	θ value	θ > 10 (rank : 914)
Query Neighborhood Hits	455	Target Neighborhood Hits	236	Shared Neighborhood Hits	85
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

ASPP1_MOUSE
NC score	0.148210 (rank : 65)	θ value	1.06291 (rank : 177)
Query Neighborhood Hits	455	Target Neighborhood Hits	1244	Shared Neighborhood Hits	249
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

NFH_MOUSE
NC score	0.147091 (rank : 66)	θ value	0.00228821 (rank : 27)
Query Neighborhood Hits	455	Target Neighborhood Hits	2247	Shared Neighborhood Hits	276
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

DDEF1_MOUSE
NC score	0.145151 (rank : 67)	θ value	0.0431538 (rank : 62)
Query Neighborhood Hits	455	Target Neighborhood Hits	592	Shared Neighborhood Hits	109
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

TXND2_HUMAN
NC score	0.144358 (rank : 68)	θ value	θ > 10 (rank : 996)
Query Neighborhood Hits	455	Target Neighborhood Hits	793	Shared Neighborhood Hits	140
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

GRAP2_MOUSE
NC score	0.143836 (rank : 69)	θ value	6.88961 (rank : 383)
Query Neighborhood Hits	455	Target Neighborhood Hits	297	Shared Neighborhood Hits	85
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

MDC1_MOUSE
NC score	0.141653 (rank : 70)	θ value	1.38821 (rank : 204)
Query Neighborhood Hits	455	Target Neighborhood Hits	998	Shared Neighborhood Hits	175
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

SH3G3_HUMAN
NC score	0.141273 (rank : 71)	θ value	θ > 10 (rank : 913)
Query Neighborhood Hits	455	Target Neighborhood Hits	222	Shared Neighborhood Hits	84
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

PRRT3_HUMAN
NC score	0.140236 (rank : 72)	θ value	4.03905 (rank : 317)
Query Neighborhood Hits	455	Target Neighborhood Hits	998	Shared Neighborhood Hits	156
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

PRG4_HUMAN
NC score	0.138044 (rank : 73)	θ value	0.0961366 (rank : 89)
Query Neighborhood Hits	455	Target Neighborhood Hits	764	Shared Neighborhood Hits	110
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

DDEF2_MOUSE
NC score	0.137939 (rank : 74)	θ value	0.00509761 (rank : 33)
Query Neighborhood Hits	455	Target Neighborhood Hits	625	Shared Neighborhood Hits	113
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

RGS3_MOUSE
NC score	0.137766 (rank : 75)	θ value	0.0330416 (rank : 60)
Query Neighborhood Hits	455	Target Neighborhood Hits	1621	Shared Neighborhood Hits	210
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

ARHG7_MOUSE
NC score	0.136816 (rank : 76)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	455	Target Neighborhood Hits	396	Shared Neighborhood Hits	103
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

AHI1_MOUSE
NC score	0.136532 (rank : 77)	θ value	0.163984 (rank : 96)
Query Neighborhood Hits	455	Target Neighborhood Hits	496	Shared Neighborhood Hits	90
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

ARHG5_HUMAN
NC score	0.136332 (rank : 78)	θ value	0.125558 (rank : 91)
Query Neighborhood Hits	455	Target Neighborhood Hits	172	Shared Neighborhood Hits	56
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

GRAP2_HUMAN
NC score	0.135732 (rank : 79)	θ value	8.99809 (rank : 427)
Query Neighborhood Hits	455	Target Neighborhood Hits	304	Shared Neighborhood Hits	86
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

NCF4_MOUSE
NC score	0.135205 (rank : 80)	θ value	θ > 10 (rank : 797)
Query Neighborhood Hits	455	Target Neighborhood Hits	177	Shared Neighborhood Hits	69
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

SNX6_MOUSE
NC score	0.135181 (rank : 81)	θ value	0.00175202 (rank : 23)
Query Neighborhood Hits	455	Target Neighborhood Hits	52	Shared Neighborhood Hits	17
SwissProt Accessions	Q6P8X1	Gene names	Snx6
Domain Architecture	No domain graphic available
Description	Sorting nexin-6.

SNX6_HUMAN
NC score	0.134735 (rank : 82)	θ value	0.00175202 (rank : 22)
Query Neighborhood Hits	455	Target Neighborhood Hits	52	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UNH7, Q9Y449	Gene names	SNX6
Domain Architecture
Description	Sorting nexin-6 (TRAF4-associated factor 2).

DDEF2_HUMAN
NC score	0.134634 (rank : 83)	θ value	0.0113563 (rank : 43)
Query Neighborhood Hits	455	Target Neighborhood Hits	599	Shared Neighborhood Hits	119
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

NCK2_HUMAN
NC score	0.134267 (rank : 84)	θ value	θ > 10 (rank : 798)
Query Neighborhood Hits	455	Target Neighborhood Hits	310	Shared Neighborhood Hits	85
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

ASPP1_HUMAN
NC score	0.133956 (rank : 85)	θ value	0.0961366 (rank : 83)
Query Neighborhood Hits	455	Target Neighborhood Hits	956	Shared Neighborhood Hits	180
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ARHG7_HUMAN
NC score	0.133492 (rank : 86)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	455	Target Neighborhood Hits	347	Shared Neighborhood Hits	94
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

DBNL_HUMAN
NC score	0.131690 (rank : 87)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	455	Target Neighborhood Hits	244	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

TARSH_HUMAN
NC score	0.131294 (rank : 88)	θ value	0.47712 (rank : 141)
Query Neighborhood Hits	455	Target Neighborhood Hits	768	Shared Neighborhood Hits	123
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

ARHGG_HUMAN
NC score	0.131125 (rank : 89)	θ value	0.00390308 (rank : 30)
Query Neighborhood Hits	455	Target Neighborhood Hits	129	Shared Neighborhood Hits	39
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ARHGG_MOUSE
NC score	0.131092 (rank : 90)	θ value	0.0736092 (rank : 73)
Query Neighborhood Hits	455	Target Neighborhood Hits	152	Shared Neighborhood Hits	51
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

GRB2_HUMAN
NC score	0.131039 (rank : 91)	θ value	θ > 10 (rank : 667)
Query Neighborhood Hits	455	Target Neighborhood Hits	310	Shared Neighborhood Hits	84
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

PCLO_HUMAN
NC score	0.130946 (rank : 92)	θ value	0.163984 (rank : 101)
Query Neighborhood Hits	455	Target Neighborhood Hits	2046	Shared Neighborhood Hits	250
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

GRB2_MOUSE
NC score	0.130679 (rank : 93)	θ value	θ > 10 (rank : 668)
Query Neighborhood Hits	455	Target Neighborhood Hits	312	Shared Neighborhood Hits	84
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

RP1L1_HUMAN
NC score	0.130393 (rank : 94)	θ value	0.000786445 (rank : 18)
Query Neighborhood Hits	455	Target Neighborhood Hits	1072	Shared Neighborhood Hits	140
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

PRG4_MOUSE
NC score	0.129563 (rank : 95)	θ value	0.62314 (rank : 151)
Query Neighborhood Hits	455	Target Neighborhood Hits	624	Shared Neighborhood Hits	97
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

DBNL_MOUSE
NC score	0.129309 (rank : 96)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	455	Target Neighborhood Hits	306	Shared Neighborhood Hits	88
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

STAC_HUMAN
NC score	0.128832 (rank : 97)	θ value	θ > 10 (rank : 942)
Query Neighborhood Hits	455	Target Neighborhood Hits	276	Shared Neighborhood Hits	80
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

SHLB1_MOUSE
NC score	0.127739 (rank : 98)	θ value	0.62314 (rank : 155)
Query Neighborhood Hits	455	Target Neighborhood Hits	101	Shared Neighborhood Hits	52
SwissProt Accessions	Q9JK48, Q8CDS9, Q8VI52, Q9CT31	Gene names	Sh3glb1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1).

SHLB2_HUMAN
NC score	0.127250 (rank : 99)	θ value	0.0252991 (rank : 56)
Query Neighborhood Hits	455	Target Neighborhood Hits	86	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NR46, Q8WY61, Q96JH9	Gene names	SH3GLB2, KIAA1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

NEBU_HUMAN
NC score	0.126983 (rank : 100)	θ value	θ > 10 (rank : 804)
Query Neighborhood Hits	455	Target Neighborhood Hits	420	Shared Neighborhood Hits	102
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

SON_MOUSE
NC score	0.126531 (rank : 101)	θ value	0.125558 (rank : 93)
Query Neighborhood Hits	455	Target Neighborhood Hits	957	Shared Neighborhood Hits	132
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SHLB1_HUMAN
NC score	0.125943 (rank : 102)	θ value	0.62314 (rank : 154)
Query Neighborhood Hits	455	Target Neighborhood Hits	96	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y371, Q9H3Z0, Q9NR47, Q9NYA9	Gene names	SH3GLB1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1) (Bax- interacting factor 1) (Bif-1).

RIMB1_HUMAN
NC score	0.125794 (rank : 103)	θ value	θ > 10 (rank : 883)
Query Neighborhood Hits	455	Target Neighborhood Hits	1479	Shared Neighborhood Hits	230
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SRRM1_MOUSE
NC score	0.125683 (rank : 104)	θ value	2.36792 (rank : 259)
Query Neighborhood Hits	455	Target Neighborhood Hits	966	Shared Neighborhood Hits	131
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

NCF1_MOUSE
NC score	0.125525 (rank : 105)	θ value	θ > 10 (rank : 795)
Query Neighborhood Hits	455	Target Neighborhood Hits	198	Shared Neighborhood Hits	75
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

SHLB2_MOUSE
NC score	0.125333 (rank : 106)	θ value	0.0431538 (rank : 65)
Query Neighborhood Hits	455	Target Neighborhood Hits	88	Shared Neighborhood Hits	41
SwissProt Accessions	Q8R3V5, Q8K140, Q91ZI7	Gene names	Sh3glb2, Kiaa1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

MUC7_HUMAN
NC score	0.125177 (rank : 107)	θ value	1.81305 (rank : 220)
Query Neighborhood Hits	455	Target Neighborhood Hits	538	Shared Neighborhood Hits	74
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

AKA12_HUMAN
NC score	0.124911 (rank : 108)	θ value	4.03905 (rank : 295)
Query Neighborhood Hits	455	Target Neighborhood Hits	825	Shared Neighborhood Hits	133
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

STAC_MOUSE
NC score	0.124901 (rank : 109)	θ value	θ > 10 (rank : 943)
Query Neighborhood Hits	455	Target Neighborhood Hits	268	Shared Neighborhood Hits	81
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

BSN_MOUSE
NC score	0.124835 (rank : 110)	θ value	4.03905 (rank : 299)
Query Neighborhood Hits	455	Target Neighborhood Hits	2057	Shared Neighborhood Hits	240
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

AHI1_HUMAN
NC score	0.124375 (rank : 111)	θ value	0.47712 (rank : 129)
Query Neighborhood Hits	455	Target Neighborhood Hits	537	Shared Neighborhood Hits	93
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

NCF4_HUMAN
NC score	0.123922 (rank : 112)	θ value	θ > 10 (rank : 796)
Query Neighborhood Hits	455	Target Neighborhood Hits	161	Shared Neighborhood Hits	62
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

STS1_HUMAN
NC score	0.123713 (rank : 113)	θ value	1.81305 (rank : 230)
Query Neighborhood Hits	455	Target Neighborhood Hits	106	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TF42, Q53GT5, Q53GT8, Q8NBV7, Q96IG9, Q96NZ2	Gene names	STS1, KIAA1959
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

NCF1_HUMAN
NC score	0.122981 (rank : 114)	θ value	θ > 10 (rank : 794)
Query Neighborhood Hits	455	Target Neighborhood Hits	198	Shared Neighborhood Hits	74
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

PELP1_HUMAN
NC score	0.122437 (rank : 115)	θ value	0.21417 (rank : 110)
Query Neighborhood Hits	455	Target Neighborhood Hits	596	Shared Neighborhood Hits	104
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

BASP_HUMAN
NC score	0.121689 (rank : 116)	θ value	0.0563607 (rank : 68)
Query Neighborhood Hits	455	Target Neighborhood Hits	321	Shared Neighborhood Hits	60
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

TAU_HUMAN
NC score	0.119958 (rank : 117)	θ value	0.00509761 (rank : 36)
Query Neighborhood Hits	455	Target Neighborhood Hits	448	Shared Neighborhood Hits	85
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

RIMB1_MOUSE
NC score	0.119781 (rank : 118)	θ value	0.813845 (rank : 170)
Query Neighborhood Hits	455	Target Neighborhood Hits	1376	Shared Neighborhood Hits	203
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

STS1_MOUSE
NC score	0.119750 (rank : 119)	θ value	1.38821 (rank : 212)
Query Neighborhood Hits	455	Target Neighborhood Hits	104	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BGG7, Q3U8Z2, Q8BMW9	Gene names	Sts1
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

PELP1_MOUSE
NC score	0.119026 (rank : 120)	θ value	0.47712 (rank : 139)
Query Neighborhood Hits	455	Target Neighborhood Hits	709	Shared Neighborhood Hits	115
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

GRAP_MOUSE
NC score	0.118878 (rank : 121)	θ value	θ > 10 (rank : 666)
Query Neighborhood Hits	455	Target Neighborhood Hits	309	Shared Neighborhood Hits	84
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

STAC3_MOUSE
NC score	0.117719 (rank : 122)	θ value	θ > 10 (rank : 941)
Query Neighborhood Hits	455	Target Neighborhood Hits	232	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

MINT_MOUSE
NC score	0.117662 (rank : 123)	θ value	0.0961366 (rank : 88)
Query Neighborhood Hits	455	Target Neighborhood Hits	1514	Shared Neighborhood Hits	204
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NGEF_HUMAN
NC score	0.117549 (rank : 124)	θ value	3.0926 (rank : 280)
Query Neighborhood Hits	455	Target Neighborhood Hits	166	Shared Neighborhood Hits	63
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

STAC3_HUMAN
NC score	0.116982 (rank : 125)	θ value	θ > 10 (rank : 940)
Query Neighborhood Hits	455	Target Neighborhood Hits	228	Shared Neighborhood Hits	70
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

BAT2_HUMAN
NC score	0.116353 (rank : 126)	θ value	2.36792 (rank : 235)
Query Neighborhood Hits	455	Target Neighborhood Hits	931	Shared Neighborhood Hits	136
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

PCLO_MOUSE
NC score	0.116332 (rank : 127)	θ value	0.21417 (rank : 109)
Query Neighborhood Hits	455	Target Neighborhood Hits	2275	Shared Neighborhood Hits	241
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

ASPP2_HUMAN
NC score	0.115574 (rank : 128)	θ value	4.03905 (rank : 298)
Query Neighborhood Hits	455	Target Neighborhood Hits	1156	Shared Neighborhood Hits	193
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

NGEF_MOUSE
NC score	0.114842 (rank : 129)	θ value	5.27518 (rank : 347)
Query Neighborhood Hits	455	Target Neighborhood Hits	228	Shared Neighborhood Hits	74
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

IASPP_MOUSE
NC score	0.114310 (rank : 130)	θ value	θ > 10 (rank : 685)
Query Neighborhood Hits	455	Target Neighborhood Hits	1024	Shared Neighborhood Hits	159
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

TMAP1_HUMAN
NC score	0.114124 (rank : 131)	θ value	θ > 10 (rank : 972)
Query Neighborhood Hits	455	Target Neighborhood Hits	140	Shared Neighborhood Hits	37
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

GRAP_HUMAN
NC score	0.113095 (rank : 132)	θ value	θ > 10 (rank : 665)
Query Neighborhood Hits	455	Target Neighborhood Hits	307	Shared Neighborhood Hits	82
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

MUC1_HUMAN
NC score	0.112305 (rank : 133)	θ value	0.0563607 (rank : 72)
Query Neighborhood Hits	455	Target Neighborhood Hits	975	Shared Neighborhood Hits	132
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

TACC2_MOUSE
NC score	0.111293 (rank : 134)	θ value	0.0431538 (rank : 66)
Query Neighborhood Hits	455	Target Neighborhood Hits	774	Shared Neighborhood Hits	137
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TACC2_HUMAN
NC score	0.110901 (rank : 135)	θ value	0.813845 (rank : 175)
Query Neighborhood Hits	455	Target Neighborhood Hits	856	Shared Neighborhood Hits	155
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

MINT_HUMAN
NC score	0.110761 (rank : 136)	θ value	0.279714 (rank : 117)
Query Neighborhood Hits	455	Target Neighborhood Hits	1291	Shared Neighborhood Hits	177
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PRR12_HUMAN
NC score	0.110307 (rank : 137)	θ value	5.27518 (rank : 353)
Query Neighborhood Hits	455	Target Neighborhood Hits	460	Shared Neighborhood Hits	78
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

MAP4_HUMAN
NC score	0.109778 (rank : 138)	θ value	θ > 10 (rank : 750)
Query Neighborhood Hits	455	Target Neighborhood Hits	428	Shared Neighborhood Hits	84
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

BCAR1_HUMAN
NC score	0.109399 (rank : 139)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	455	Target Neighborhood Hits	554	Shared Neighborhood Hits	132
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

EFS_MOUSE
NC score	0.108934 (rank : 140)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	455	Target Neighborhood Hits	389	Shared Neighborhood Hits	115
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

OSTF1_HUMAN
NC score	0.108631 (rank : 141)	θ value	θ > 10 (rank : 825)
Query Neighborhood Hits	455	Target Neighborhood Hits	466	Shared Neighborhood Hits	80
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

K0494_MOUSE
NC score	0.108503 (rank : 142)	θ value	0.0330416 (rank : 58)
Query Neighborhood Hits	455	Target Neighborhood Hits	241	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BGQ6, Q3TQN6, Q8BJV7, Q8C0R1	Gene names	Kiaa0494
Domain Architecture	No domain graphic available
Description	Uncharacterized calcium-binding protein KIAA0494.

SNX5_MOUSE
NC score	0.107746 (rank : 143)	θ value	0.163984 (rank : 104)
Query Neighborhood Hits	455	Target Neighborhood Hits	81	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D8U8, Q543N9	Gene names	Snx5
Domain Architecture
Description	Sorting nexin-5.

SPTA2_HUMAN
NC score	0.107484 (rank : 144)	θ value	θ > 10 (rank : 932)
Query Neighborhood Hits	455	Target Neighborhood Hits	888	Shared Neighborhood Hits	158
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

IASPP_HUMAN
NC score	0.107452 (rank : 145)	θ value	θ > 10 (rank : 684)
Query Neighborhood Hits	455	Target Neighborhood Hits	688	Shared Neighborhood Hits	126
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

SNX5_HUMAN
NC score	0.107049 (rank : 146)	θ value	0.163984 (rank : 103)
Query Neighborhood Hits	455	Target Neighborhood Hits	79	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y5X3, Q52LC4, Q9BWP0	Gene names	SNX5
Domain Architecture
Description	Sorting nexin-5.

OSTF1_MOUSE
NC score	0.106707 (rank : 147)	θ value	θ > 10 (rank : 826)
Query Neighborhood Hits	455	Target Neighborhood Hits	467	Shared Neighborhood Hits	80
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

NCOA6_HUMAN
NC score	0.106547 (rank : 148)	θ value	1.81305 (rank : 222)
Query Neighborhood Hits	455	Target Neighborhood Hits	1202	Shared Neighborhood Hits	151
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NCOA6_MOUSE
NC score	0.105840 (rank : 149)	θ value	1.81305 (rank : 223)
Query Neighborhood Hits	455	Target Neighborhood Hits	1076	Shared Neighborhood Hits	146
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

DGKK_HUMAN
NC score	0.105459 (rank : 150)	θ value	0.00228821 (rank : 25)
Query Neighborhood Hits	455	Target Neighborhood Hits	378	Shared Neighborhood Hits	66
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

ZN645_HUMAN
NC score	0.104895 (rank : 151)	θ value	0.125558 (rank : 95)
Query Neighborhood Hits	455	Target Neighborhood Hits	265	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

EFS_HUMAN
NC score	0.104573 (rank : 152)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	455	Target Neighborhood Hits	348	Shared Neighborhood Hits	104
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

VAV_HUMAN
NC score	0.104420 (rank : 153)	θ value	θ > 10 (rank : 1005)
Query Neighborhood Hits	455	Target Neighborhood Hits	452	Shared Neighborhood Hits	100
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

VAV_MOUSE
NC score	0.104256 (rank : 154)	θ value	θ > 10 (rank : 1006)
Query Neighborhood Hits	455	Target Neighborhood Hits	430	Shared Neighborhood Hits	91
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

TAF4_HUMAN
NC score	0.103745 (rank : 155)	θ value	θ > 10 (rank : 958)
Query Neighborhood Hits	455	Target Neighborhood Hits	687	Shared Neighborhood Hits	98
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

SET1A_HUMAN
NC score	0.103432 (rank : 156)	θ value	0.125558 (rank : 92)
Query Neighborhood Hits	455	Target Neighborhood Hits	690	Shared Neighborhood Hits	85
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

MLL2_HUMAN
NC score	0.102561 (rank : 157)	θ value	2.36792 (rank : 249)
Query Neighborhood Hits	455	Target Neighborhood Hits	1788	Shared Neighborhood Hits	188
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

CRKL_HUMAN
NC score	0.102457 (rank : 158)	θ value	6.88961 (rank : 374)
Query Neighborhood Hits	455	Target Neighborhood Hits	313	Shared Neighborhood Hits	77
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

MAP1A_HUMAN
NC score	0.102107 (rank : 159)	θ value	θ > 10 (rank : 746)
Query Neighborhood Hits	455	Target Neighborhood Hits	1626	Shared Neighborhood Hits	217
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

TAU_MOUSE
NC score	0.102050 (rank : 160)	θ value	1.81305 (rank : 231)
Query Neighborhood Hits	455	Target Neighborhood Hits	502	Shared Neighborhood Hits	87
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

IWS1_HUMAN
NC score	0.101947 (rank : 161)	θ value	θ > 10 (rank : 697)
Query Neighborhood Hits	455	Target Neighborhood Hits	1241	Shared Neighborhood Hits	167
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SYCP1_MOUSE
NC score	0.101597 (rank : 162)	θ value	0.0148317 (rank : 51)
Query Neighborhood Hits	455	Target Neighborhood Hits	1456	Shared Neighborhood Hits	147
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

BCAR1_MOUSE
NC score	0.101503 (rank : 163)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	455	Target Neighborhood Hits	438	Shared Neighborhood Hits	121
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

INCE_HUMAN
NC score	0.101429 (rank : 164)	θ value	0.47712 (rank : 133)
Query Neighborhood Hits	455	Target Neighborhood Hits	978	Shared Neighborhood Hits	122
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

IWS1_MOUSE
NC score	0.100759 (rank : 165)	θ value	5.27518 (rank : 339)
Query Neighborhood Hits	455	Target Neighborhood Hits	1258	Shared Neighborhood Hits	169
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

GSCR1_HUMAN
NC score	0.100455 (rank : 166)	θ value	2.36792 (rank : 244)
Query Neighborhood Hits	455	Target Neighborhood Hits	674	Shared Neighborhood Hits	94
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

CT032_HUMAN
NC score	0.100261 (rank : 167)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	455	Target Neighborhood Hits	235	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

SMC1A_MOUSE
NC score	0.099669 (rank : 168)	θ value	0.279714 (rank : 120)
Query Neighborhood Hits	455	Target Neighborhood Hits	1384	Shared Neighborhood Hits	151
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

CRKL_MOUSE
NC score	0.099643 (rank : 169)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	455	Target Neighborhood Hits	307	Shared Neighborhood Hits	78
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

MAGE1_HUMAN
NC score	0.099540 (rank : 170)	θ value	θ > 10 (rank : 745)
Query Neighborhood Hits	455	Target Neighborhood Hits	1389	Shared Neighborhood Hits	178
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

DYNA_HUMAN
NC score	0.099457 (rank : 171)	θ value	0.0330416 (rank : 57)
Query Neighborhood Hits	455	Target Neighborhood Hits	1194	Shared Neighborhood Hits	136
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

SMC1A_HUMAN
NC score	0.099198 (rank : 172)	θ value	0.279714 (rank : 119)
Query Neighborhood Hits	455	Target Neighborhood Hits	1346	Shared Neighborhood Hits	149
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

TGON2_HUMAN
NC score	0.099143 (rank : 173)	θ value	θ > 10 (rank : 970)
Query Neighborhood Hits	455	Target Neighborhood Hits	1037	Shared Neighborhood Hits	151
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

BSN_HUMAN
NC score	0.099016 (rank : 174)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	455	Target Neighborhood Hits	1537	Shared Neighborhood Hits	188
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

MYO1E_HUMAN
NC score	0.098124 (rank : 175)	θ value	0.813845 (rank : 168)
Query Neighborhood Hits	455	Target Neighborhood Hits	293	Shared Neighborhood Hits	102
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

ARHGF_HUMAN
NC score	0.097946 (rank : 176)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	455	Target Neighborhood Hits	214	Shared Neighborhood Hits	50
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

PRP2_MOUSE
NC score	0.097857 (rank : 177)	θ value	θ > 10 (rank : 854)
Query Neighborhood Hits	455	Target Neighborhood Hits	347	Shared Neighborhood Hits	56
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

SRCA_HUMAN
NC score	0.097634 (rank : 178)	θ value	0.00175202 (rank : 24)
Query Neighborhood Hits	455	Target Neighborhood Hits	380	Shared Neighborhood Hits	63
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

SPR1B_MOUSE
NC score	0.097596 (rank : 179)	θ value	0.813845 (rank : 172)
Query Neighborhood Hits	455	Target Neighborhood Hits	395	Shared Neighborhood Hits	80
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

VAV2_HUMAN
NC score	0.097417 (rank : 180)	θ value	θ > 10 (rank : 1001)
Query Neighborhood Hits	455	Target Neighborhood Hits	453	Shared Neighborhood Hits	88
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
NC score	0.097366 (rank : 181)	θ value	θ > 10 (rank : 1002)
Query Neighborhood Hits	455	Target Neighborhood Hits	456	Shared Neighborhood Hits	88
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

GOGB1_HUMAN
NC score	0.096673 (rank : 182)	θ value	0.0431538 (rank : 63)
Query Neighborhood Hits	455	Target Neighborhood Hits	2297	Shared Neighborhood Hits	195
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

CRK_MOUSE
NC score	0.096304 (rank : 183)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	455	Target Neighborhood Hits	314	Shared Neighborhood Hits	79
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

NPHP1_HUMAN
NC score	0.096235 (rank : 184)	θ value	8.99809 (rank : 436)
Query Neighborhood Hits	455	Target Neighborhood Hits	288	Shared Neighborhood Hits	83
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

TCOF_MOUSE
NC score	0.096208 (rank : 185)	θ value	4.03905 (rank : 323)
Query Neighborhood Hits	455	Target Neighborhood Hits	471	Shared Neighborhood Hits	77
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

AMOT_HUMAN
NC score	0.095820 (rank : 186)	θ value	0.813845 (rank : 158)
Query Neighborhood Hits	455	Target Neighborhood Hits	712	Shared Neighborhood Hits	118
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

NPHP1_MOUSE
NC score	0.095810 (rank : 187)	θ value	θ > 10 (rank : 816)
Query Neighborhood Hits	455	Target Neighborhood Hits	267	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

BCL9_HUMAN
NC score	0.095728 (rank : 188)	θ value	0.62314 (rank : 143)
Query Neighborhood Hits	455	Target Neighborhood Hits	1008	Shared Neighborhood Hits	124
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

SRCA_MOUSE
NC score	0.095500 (rank : 189)	θ value	0.00869519 (rank : 42)
Query Neighborhood Hits	455	Target Neighborhood Hits	212	Shared Neighborhood Hits	42
SwissProt Accessions	Q7TQ48, Q8BS43	Gene names	Srl, Sar
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

CS016_HUMAN
NC score	0.095464 (rank : 190)	θ value	3.0926 (rank : 270)
Query Neighborhood Hits	455	Target Neighborhood Hits	310	Shared Neighborhood Hits	59
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

LAD1_MOUSE
NC score	0.095308 (rank : 191)	θ value	θ > 10 (rank : 717)
Query Neighborhood Hits	455	Target Neighborhood Hits	391	Shared Neighborhood Hits	87
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

RUSC1_HUMAN
NC score	0.095264 (rank : 192)	θ value	3.0926 (rank : 287)
Query Neighborhood Hits	455	Target Neighborhood Hits	226	Shared Neighborhood Hits	73
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

PLCG1_MOUSE
NC score	0.094906 (rank : 193)	θ value	θ > 10 (rank : 843)
Query Neighborhood Hits	455	Target Neighborhood Hits	314	Shared Neighborhood Hits	80
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

TARA_HUMAN
NC score	0.094450 (rank : 194)	θ value	θ > 10 (rank : 959)
Query Neighborhood Hits	455	Target Neighborhood Hits	1626	Shared Neighborhood Hits	209
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

NEST_HUMAN
NC score	0.094135 (rank : 195)	θ value	1.06291 (rank : 191)
Query Neighborhood Hits	455	Target Neighborhood Hits	1305	Shared Neighborhood Hits	163
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

CRK_HUMAN
NC score	0.094127 (rank : 196)	θ value	θ > 10 (rank : 593)
Query Neighborhood Hits	455	Target Neighborhood Hits	308	Shared Neighborhood Hits	78
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

MAP4_MOUSE
NC score	0.093868 (rank : 197)	θ value	θ > 10 (rank : 751)
Query Neighborhood Hits	455	Target Neighborhood Hits	409	Shared Neighborhood Hits	77
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

CK024_HUMAN
NC score	0.093851 (rank : 198)	θ value	θ > 10 (rank : 569)
Query Neighborhood Hits	455	Target Neighborhood Hits	408	Shared Neighborhood Hits	85
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

MLL4_HUMAN
NC score	0.093823 (rank : 199)	θ value	0.21417 (rank : 106)
Query Neighborhood Hits	455	Target Neighborhood Hits	722	Shared Neighborhood Hits	92
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

ARHG4_HUMAN
NC score	0.093548 (rank : 200)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	455	Target Neighborhood Hits	242	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

SMC2_HUMAN
NC score	0.093313 (rank : 201)	θ value	1.81305 (rank : 229)
Query Neighborhood Hits	455	Target Neighborhood Hits	1405	Shared Neighborhood Hits	149
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

HOOK3_HUMAN
NC score	0.093212 (rank : 202)	θ value	0.0563607 (rank : 70)
Query Neighborhood Hits	455	Target Neighborhood Hits	1070	Shared Neighborhood Hits	120
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

LARP4_HUMAN
NC score	0.093211 (rank : 203)	θ value	0.000158464 (rank : 16)
Query Neighborhood Hits	455	Target Neighborhood Hits	69	Shared Neighborhood Hits	15
SwissProt Accessions	Q71RC2, Q5CZ97, Q96NF9	Gene names	LARP4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

K1802_MOUSE
NC score	0.093108 (rank : 204)	θ value	2.36792 (rank : 246)
Query Neighborhood Hits	455	Target Neighborhood Hits	1596	Shared Neighborhood Hits	158
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MUC2_HUMAN
NC score	0.092973 (rank : 205)	θ value	2.36792 (rank : 250)
Query Neighborhood Hits	455	Target Neighborhood Hits	906	Shared Neighborhood Hits	104
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

BCL9_MOUSE
NC score	0.092914 (rank : 206)	θ value	0.47712 (rank : 132)
Query Neighborhood Hits	455	Target Neighborhood Hits	770	Shared Neighborhood Hits	99
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

SYCP1_HUMAN
NC score	0.092371 (rank : 207)	θ value	0.813845 (rank : 173)
Query Neighborhood Hits	455	Target Neighborhood Hits	1313	Shared Neighborhood Hits	131
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

ARHG9_HUMAN
NC score	0.092323 (rank : 208)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	455	Target Neighborhood Hits	235	Shared Neighborhood Hits	78
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

CCNK_MOUSE
NC score	0.091741 (rank : 209)	θ value	0.00869519 (rank : 40)
Query Neighborhood Hits	455	Target Neighborhood Hits	350	Shared Neighborhood Hits	58
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

NASP_HUMAN
NC score	0.091603 (rank : 210)	θ value	6.88961 (rank : 395)
Query Neighborhood Hits	455	Target Neighborhood Hits	709	Shared Neighborhood Hits	116
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

BAT2_MOUSE
NC score	0.091372 (rank : 211)	θ value	5.27518 (rank : 328)
Query Neighborhood Hits	455	Target Neighborhood Hits	947	Shared Neighborhood Hits	142
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAT3_MOUSE
NC score	0.090659 (rank : 212)	θ value	0.62314 (rank : 142)
Query Neighborhood Hits	455	Target Neighborhood Hits	518	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

SPR1A_MOUSE
NC score	0.090587 (rank : 213)	θ value	0.365318 (rank : 127)
Query Neighborhood Hits	455	Target Neighborhood Hits	343	Shared Neighborhood Hits	68
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

LAD1_HUMAN
NC score	0.090359 (rank : 214)	θ value	θ > 10 (rank : 716)
Query Neighborhood Hits	455	Target Neighborhood Hits	441	Shared Neighborhood Hits	94
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

SRRM1_HUMAN
NC score	0.090199 (rank : 215)	θ value	θ > 10 (rank : 937)
Query Neighborhood Hits	455	Target Neighborhood Hits	690	Shared Neighborhood Hits	87
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

MYH11_MOUSE
NC score	0.089995 (rank : 216)	θ value	0.813845 (rank : 166)
Query Neighborhood Hits	455	Target Neighborhood Hits	1777	Shared Neighborhood Hits	165
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

SMC2_MOUSE
NC score	0.089943 (rank : 217)	θ value	1.06291 (rank : 196)
Query Neighborhood Hits	455	Target Neighborhood Hits	1131	Shared Neighborhood Hits	127
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

HOOK3_MOUSE
NC score	0.089863 (rank : 218)	θ value	0.279714 (rank : 113)
Query Neighborhood Hits	455	Target Neighborhood Hits	1007	Shared Neighborhood Hits	116
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

PCNT_HUMAN
NC score	0.089550 (rank : 219)	θ value	θ > 10 (rank : 828)
Query Neighborhood Hits	455	Target Neighborhood Hits	1551	Shared Neighborhood Hits	167
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

CUTL1_HUMAN
NC score	0.089534 (rank : 220)	θ value	4.03905 (rank : 302)
Query Neighborhood Hits	455	Target Neighborhood Hits	1574	Shared Neighborhood Hits	183
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

RIMB2_HUMAN
NC score	0.089498 (rank : 221)	θ value	θ > 10 (rank : 884)
Query Neighborhood Hits	455	Target Neighborhood Hits	263	Shared Neighborhood Hits	68
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RIMB2_MOUSE
NC score	0.089379 (rank : 222)	θ value	θ > 10 (rank : 885)
Query Neighborhood Hits	455	Target Neighborhood Hits	246	Shared Neighborhood Hits	66
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RRBP1_MOUSE
NC score	0.089253 (rank : 223)	θ value	θ > 10 (rank : 890)
Query Neighborhood Hits	455	Target Neighborhood Hits	1650	Shared Neighborhood Hits	170
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SPTA1_HUMAN
NC score	0.089161 (rank : 224)	θ value	1.06291 (rank : 197)
Query Neighborhood Hits	455	Target Neighborhood Hits	748	Shared Neighborhood Hits	147
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

ES8L3_MOUSE
NC score	0.089153 (rank : 225)	θ value	1.81305 (rank : 216)
Query Neighborhood Hits	455	Target Neighborhood Hits	168	Shared Neighborhood Hits	69
SwissProt Accessions	Q91WL0, Q3TJ14	Gene names	Eps8l3, Eps8r3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

ENAH_MOUSE
NC score	0.089097 (rank : 226)	θ value	6.88961 (rank : 378)
Query Neighborhood Hits	455	Target Neighborhood Hits	919	Shared Neighborhood Hits	132
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

TCOF_HUMAN
NC score	0.089039 (rank : 227)	θ value	4.03905 (rank : 322)
Query Neighborhood Hits	455	Target Neighborhood Hits	543	Shared Neighborhood Hits	85
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

CCD21_MOUSE
NC score	0.089004 (rank : 228)	θ value	2.36792 (rank : 238)
Query Neighborhood Hits	455	Target Neighborhood Hits	1135	Shared Neighborhood Hits	138
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

MYH10_HUMAN
NC score	0.088774 (rank : 229)	θ value	0.62314 (rank : 149)
Query Neighborhood Hits	455	Target Neighborhood Hits	1620	Shared Neighborhood Hits	157
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
NC score	0.088703 (rank : 230)	θ value	0.365318 (rank : 124)
Query Neighborhood Hits	455	Target Neighborhood Hits	1612	Shared Neighborhood Hits	156
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

ARHG9_MOUSE
NC score	0.088657 (rank : 231)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	455	Target Neighborhood Hits	234	Shared Neighborhood Hits	76
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

CUTL1_MOUSE
NC score	0.088560 (rank : 232)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	455	Target Neighborhood Hits	1620	Shared Neighborhood Hits	195
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

MY18B_HUMAN
NC score	0.088388 (rank : 233)	θ value	0.163984 (rank : 99)
Query Neighborhood Hits	455	Target Neighborhood Hits	1299	Shared Neighborhood Hits	164
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

TACC3_HUMAN
NC score	0.088070 (rank : 234)	θ value	θ > 10 (rank : 954)
Query Neighborhood Hits	455	Target Neighborhood Hits	779	Shared Neighborhood Hits	131
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

TXLNB_HUMAN
NC score	0.087929 (rank : 235)	θ value	1.38821 (rank : 213)
Query Neighborhood Hits	455	Target Neighborhood Hits	912	Shared Neighborhood Hits	154
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

TPM2_HUMAN
NC score	0.087339 (rank : 236)	θ value	0.21417 (rank : 111)
Query Neighborhood Hits	455	Target Neighborhood Hits	677	Shared Neighborhood Hits	94
SwissProt Accessions	P07951, P06468, Q13894, Q53FM4, Q5TCU4, Q5TCU7, Q9UH67	Gene names	TPM2, TMSB
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

RRBP1_HUMAN
NC score	0.087296 (rank : 237)	θ value	θ > 10 (rank : 889)
Query Neighborhood Hits	455	Target Neighborhood Hits	1306	Shared Neighborhood Hits	152
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

RFIP3_HUMAN
NC score	0.087215 (rank : 238)	θ value	3.0926 (rank : 286)
Query Neighborhood Hits	455	Target Neighborhood Hits	1055	Shared Neighborhood Hits	132
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

MYH9_HUMAN
NC score	0.087116 (rank : 239)	θ value	0.813845 (rank : 167)
Query Neighborhood Hits	455	Target Neighborhood Hits	1762	Shared Neighborhood Hits	167
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

CI093_HUMAN
NC score	0.086362 (rank : 240)	θ value	θ > 10 (rank : 560)
Query Neighborhood Hits	455	Target Neighborhood Hits	1088	Shared Neighborhood Hits	127
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

PRP1_HUMAN
NC score	0.086046 (rank : 241)	θ value	θ > 10 (rank : 853)
Query Neighborhood Hits	455	Target Neighborhood Hits	385	Shared Neighborhood Hits	65
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

SM1L2_MOUSE
NC score	0.085780 (rank : 242)	θ value	2.36792 (rank : 255)
Query Neighborhood Hits	455	Target Neighborhood Hits	918	Shared Neighborhood Hits	115
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

GOGA5_MOUSE
NC score	0.085763 (rank : 243)	θ value	2.36792 (rank : 243)
Query Neighborhood Hits	455	Target Neighborhood Hits	1434	Shared Neighborhood Hits	150
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

TXLNA_HUMAN
NC score	0.085205 (rank : 244)	θ value	2.36792 (rank : 262)
Query Neighborhood Hits	455	Target Neighborhood Hits	982	Shared Neighborhood Hits	133
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

TPM2_MOUSE
NC score	0.085102 (rank : 245)	θ value	0.365318 (rank : 128)
Query Neighborhood Hits	455	Target Neighborhood Hits	676	Shared Neighborhood Hits	95
SwissProt Accessions	P58774, P02560, P46901	Gene names	Tpm2, Tpm-2
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

GOGA1_HUMAN
NC score	0.085058 (rank : 246)	θ value	1.06291 (rank : 189)
Query Neighborhood Hits	455	Target Neighborhood Hits	1222	Shared Neighborhood Hits	135
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

MYH9_MOUSE
NC score	0.084818 (rank : 247)	θ value	8.99809 (rank : 433)
Query Neighborhood Hits	455	Target Neighborhood Hits	1829	Shared Neighborhood Hits	173
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

NFH_HUMAN
NC score	0.084423 (rank : 248)	θ value	0.47712 (rank : 137)
Query Neighborhood Hits	455	Target Neighborhood Hits	1242	Shared Neighborhood Hits	167
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

AKAP9_HUMAN
NC score	0.084413 (rank : 249)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	455	Target Neighborhood Hits	1710	Shared Neighborhood Hits	158
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

CCD21_HUMAN
NC score	0.084145 (rank : 250)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	455	Target Neighborhood Hits	1228	Shared Neighborhood Hits	141
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

RUSC1_MOUSE
NC score	0.083907 (rank : 251)	θ value	θ > 10 (rank : 897)
Query Neighborhood Hits	455	Target Neighborhood Hits	206	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

CENPE_HUMAN
NC score	0.083880 (rank : 252)	θ value	0.163984 (rank : 98)
Query Neighborhood Hits	455	Target Neighborhood Hits	2060	Shared Neighborhood Hits	176
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CCD46_MOUSE
NC score	0.083738 (rank : 253)	θ value	8.99809 (rank : 416)
Query Neighborhood Hits	455	Target Neighborhood Hits	1405	Shared Neighborhood Hits	160
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

SM1L2_HUMAN
NC score	0.083668 (rank : 254)	θ value	θ > 10 (rank : 917)
Query Neighborhood Hits	455	Target Neighborhood Hits	1019	Shared Neighborhood Hits	121
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

MYO1F_HUMAN
NC score	0.083338 (rank : 255)	θ value	θ > 10 (rank : 786)
Query Neighborhood Hits	455	Target Neighborhood Hits	275	Shared Neighborhood Hits	94
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

MTSS1_MOUSE
NC score	0.083313 (rank : 256)	θ value	θ > 10 (rank : 768)
Query Neighborhood Hits	455	Target Neighborhood Hits	592	Shared Neighborhood Hits	117
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

MYO1F_MOUSE
NC score	0.083066 (rank : 257)	θ value	θ > 10 (rank : 787)
Query Neighborhood Hits	455	Target Neighborhood Hits	262	Shared Neighborhood Hits	88
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

NOXO1_MOUSE
NC score	0.082827 (rank : 258)	θ value	θ > 10 (rank : 814)
Query Neighborhood Hits	455	Target Neighborhood Hits	114	Shared Neighborhood Hits	54
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

NIPBL_HUMAN
NC score	0.082588 (rank : 259)	θ value	θ > 10 (rank : 811)
Query Neighborhood Hits	455	Target Neighborhood Hits	1311	Shared Neighborhood Hits	160
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

SNX18_HUMAN
NC score	0.082539 (rank : 260)	θ value	θ > 10 (rank : 923)
Query Neighborhood Hits	455	Target Neighborhood Hits	207	Shared Neighborhood Hits	67
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SRRM2_MOUSE
NC score	0.082471 (rank : 261)	θ value	θ > 10 (rank : 939)
Query Neighborhood Hits	455	Target Neighborhood Hits	1470	Shared Neighborhood Hits	168
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

CI039_HUMAN
NC score	0.082396 (rank : 262)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	455	Target Neighborhood Hits	1171	Shared Neighborhood Hits	130
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

BAT3_HUMAN
NC score	0.082180 (rank : 263)	θ value	2.36792 (rank : 236)
Query Neighborhood Hits	455	Target Neighborhood Hits	490	Shared Neighborhood Hits	75
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

CIZ1_HUMAN
NC score	0.082144 (rank : 264)	θ value	0.62314 (rank : 146)
Query Neighborhood Hits	455	Target Neighborhood Hits	359	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

AZI1_MOUSE
NC score	0.082111 (rank : 265)	θ value	1.06291 (rank : 178)
Query Neighborhood Hits	455	Target Neighborhood Hits	990	Shared Neighborhood Hits	121
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

TPR_HUMAN
NC score	0.082078 (rank : 266)	θ value	4.03905 (rank : 324)
Query Neighborhood Hits	455	Target Neighborhood Hits	1921	Shared Neighborhood Hits	176
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TCRG1_MOUSE
NC score	0.081969 (rank : 267)	θ value	θ > 10 (rank : 967)
Query Neighborhood Hits	455	Target Neighborhood Hits	947	Shared Neighborhood Hits	131
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

OGFR_MOUSE
NC score	0.081921 (rank : 268)	θ value	θ > 10 (rank : 822)
Query Neighborhood Hits	455	Target Neighborhood Hits	584	Shared Neighborhood Hits	99
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

TP53B_MOUSE
NC score	0.081916 (rank : 269)	θ value	θ > 10 (rank : 976)
Query Neighborhood Hits	455	Target Neighborhood Hits	644	Shared Neighborhood Hits	118
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

SNX18_MOUSE
NC score	0.081876 (rank : 270)	θ value	θ > 10 (rank : 924)
Query Neighborhood Hits	455	Target Neighborhood Hits	198	Shared Neighborhood Hits	65
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

NUF2_HUMAN
NC score	0.081872 (rank : 271)	θ value	3.0926 (rank : 281)
Query Neighborhood Hits	455	Target Neighborhood Hits	661	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

MYH11_HUMAN
NC score	0.081677 (rank : 272)	θ value	0.163984 (rank : 100)
Query Neighborhood Hits	455	Target Neighborhood Hits	1806	Shared Neighborhood Hits	171
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MOT8_MOUSE
NC score	0.081523 (rank : 273)	θ value	0.00298849 (rank : 29)
Query Neighborhood Hits	455	Target Neighborhood Hits	96	Shared Neighborhood Hits	20
SwissProt Accessions	O70324, Q8K3S9	Gene names	Slc16a2, Mct8, Xpct
Domain Architecture	No domain graphic available
Description	Monocarboxylate transporter 8 (MCT 8) (Solute carrier family 16 member 2) (X-linked PEST-containing transporter).

INCE_MOUSE
NC score	0.081321 (rank : 274)	θ value	5.27518 (rank : 338)
Query Neighborhood Hits	455	Target Neighborhood Hits	903	Shared Neighborhood Hits	104
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

NFM_HUMAN
NC score	0.081200 (rank : 275)	θ value	0.21417 (rank : 108)
Query Neighborhood Hits	455	Target Neighborhood Hits	1328	Shared Neighborhood Hits	190
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

CING_HUMAN
NC score	0.081192 (rank : 276)	θ value	6.88961 (rank : 373)
Query Neighborhood Hits	455	Target Neighborhood Hits	1275	Shared Neighborhood Hits	139
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

SELPL_HUMAN
NC score	0.081110 (rank : 277)	θ value	θ > 10 (rank : 904)
Query Neighborhood Hits	455	Target Neighborhood Hits	68	Shared Neighborhood Hits	17
SwissProt Accessions	Q14242, Q12775	Gene names	SELPLG
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand) (CD162 antigen).

CENPF_HUMAN
NC score	0.081009 (rank : 278)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	455	Target Neighborhood Hits	1932	Shared Neighborhood Hits	164
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

NOL3_MOUSE
NC score	0.080923 (rank : 279)	θ value	0.0736092 (rank : 80)
Query Neighborhood Hits	455	Target Neighborhood Hits	97	Shared Neighborhood Hits	23
SwissProt Accessions	Q9D1X0	Gene names	Nol3
Domain Architecture
Description	Nucleolar protein 3.

CK5P2_MOUSE
NC score	0.080911 (rank : 280)	θ value	3.0926 (rank : 269)
Query Neighborhood Hits	455	Target Neighborhood Hits	1151	Shared Neighborhood Hits	134
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

TCRG1_HUMAN
NC score	0.080866 (rank : 281)	θ value	θ > 10 (rank : 966)
Query Neighborhood Hits	455	Target Neighborhood Hits	929	Shared Neighborhood Hits	128
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

FLIP1_HUMAN
NC score	0.080748 (rank : 282)	θ value	θ > 10 (rank : 639)
Query Neighborhood Hits	455	Target Neighborhood Hits	1405	Shared Neighborhood Hits	150
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

CP135_MOUSE
NC score	0.080721 (rank : 283)	θ value	θ > 10 (rank : 586)
Query Neighborhood Hits	455	Target Neighborhood Hits	1278	Shared Neighborhood Hits	132
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

GOGA4_HUMAN
NC score	0.080379 (rank : 284)	θ value	θ > 10 (rank : 658)
Query Neighborhood Hits	455	Target Neighborhood Hits	2034	Shared Neighborhood Hits	182
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

PEX13_HUMAN
NC score	0.080378 (rank : 285)	θ value	θ > 10 (rank : 832)
Query Neighborhood Hits	455	Target Neighborhood Hits	128	Shared Neighborhood Hits	58
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

RTN4_MOUSE
NC score	0.080206 (rank : 286)	θ value	2.36792 (rank : 254)
Query Neighborhood Hits	455	Target Neighborhood Hits	341	Shared Neighborhood Hits	79
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

CP250_HUMAN
NC score	0.080156 (rank : 287)	θ value	θ > 10 (rank : 587)
Query Neighborhood Hits	455	Target Neighborhood Hits	1805	Shared Neighborhood Hits	164
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CCD96_HUMAN
NC score	0.080146 (rank : 288)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	455	Target Neighborhood Hits	595	Shared Neighborhood Hits	103
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

TRIPB_HUMAN
NC score	0.080060 (rank : 289)	θ value	θ > 10 (rank : 987)
Query Neighborhood Hits	455	Target Neighborhood Hits	1587	Shared Neighborhood Hits	148
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

CCD46_HUMAN
NC score	0.079934 (rank : 290)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	455	Target Neighborhood Hits	1430	Shared Neighborhood Hits	144
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

PCNT_MOUSE
NC score	0.079922 (rank : 291)	θ value	3.0926 (rank : 282)
Query Neighborhood Hits	455	Target Neighborhood Hits	1207	Shared Neighborhood Hits	133
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

GLU2B_HUMAN
NC score	0.079894 (rank : 292)	θ value	1.06291 (rank : 188)
Query Neighborhood Hits	455	Target Neighborhood Hits	377	Shared Neighborhood Hits	64
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

SHAN1_HUMAN
NC score	0.079873 (rank : 293)	θ value	8.99809 (rank : 444)
Query Neighborhood Hits	455	Target Neighborhood Hits	1041	Shared Neighborhood Hits	135
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

DYNA_MOUSE
NC score	0.079819 (rank : 294)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	455	Target Neighborhood Hits	1084	Shared Neighborhood Hits	124
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

NELFA_MOUSE
NC score	0.079798 (rank : 295)	θ value	0.365318 (rank : 125)
Query Neighborhood Hits	455	Target Neighborhood Hits	195	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

CJ078_MOUSE
NC score	0.079770 (rank : 296)	θ value	θ > 10 (rank : 566)
Query Neighborhood Hits	455	Target Neighborhood Hits	559	Shared Neighborhood Hits	89
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CNTRB_MOUSE
NC score	0.079758 (rank : 297)	θ value	θ > 10 (rank : 581)
Query Neighborhood Hits	455	Target Neighborhood Hits	1029	Shared Neighborhood Hits	143
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

MY18A_MOUSE
NC score	0.079746 (rank : 298)	θ value	θ > 10 (rank : 773)
Query Neighborhood Hits	455	Target Neighborhood Hits	1989	Shared Neighborhood Hits	178
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

GOGA1_MOUSE
NC score	0.079740 (rank : 299)	θ value	θ > 10 (rank : 655)
Query Neighborhood Hits	455	Target Neighborhood Hits	994	Shared Neighborhood Hits	115
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

PLCG2_HUMAN
NC score	0.079724 (rank : 300)	θ value	θ > 10 (rank : 844)
Query Neighborhood Hits	455	Target Neighborhood Hits	280	Shared Neighborhood Hits	74
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

GCC2_MOUSE
NC score	0.079696 (rank : 301)	θ value	θ > 10 (rank : 649)
Query Neighborhood Hits	455	Target Neighborhood Hits	1619	Shared Neighborhood Hits	153
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

PEX13_MOUSE
NC score	0.079615 (rank : 302)	θ value	θ > 10 (rank : 833)
Query Neighborhood Hits	455	Target Neighborhood Hits	126	Shared Neighborhood Hits	58
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

EEA1_MOUSE
NC score	0.079491 (rank : 303)	θ value	1.06291 (rank : 184)
Query Neighborhood Hits	455	Target Neighborhood Hits	1637	Shared Neighborhood Hits	149
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

M3KL4_HUMAN
NC score	0.079399 (rank : 304)	θ value	0.00390308 (rank : 31)
Query Neighborhood Hits	455	Target Neighborhood Hits	1087	Shared Neighborhood Hits	112
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

M3K9_HUMAN
NC score	0.079376 (rank : 305)	θ value	5.44631e-05 (rank : 12)
Query Neighborhood Hits	455	Target Neighborhood Hits	1123	Shared Neighborhood Hits	119
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

TCGAP_HUMAN
NC score	0.079355 (rank : 306)	θ value	θ > 10 (rank : 964)
Query Neighborhood Hits	455	Target Neighborhood Hits	872	Shared Neighborhood Hits	141
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

CASP_MOUSE
NC score	0.078989 (rank : 307)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	455	Target Neighborhood Hits	1152	Shared Neighborhood Hits	132
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

LRRF1_HUMAN
NC score	0.078938 (rank : 308)	θ value	3.0926 (rank : 277)
Query Neighborhood Hits	455	Target Neighborhood Hits	625	Shared Neighborhood Hits	96
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

CLUL1_HUMAN
NC score	0.078901 (rank : 309)	θ value	0.21417 (rank : 105)
Query Neighborhood Hits	455	Target Neighborhood Hits	62	Shared Neighborhood Hits	15
SwissProt Accessions	Q15846	Gene names	CLUL1
Domain Architecture	No domain graphic available
Description	Clusterin-like protein 1 precursor (Retinal-specific clusterin-like protein).

FLIP1_MOUSE
NC score	0.078825 (rank : 310)	θ value	θ > 10 (rank : 640)
Query Neighborhood Hits	455	Target Neighborhood Hits	1176	Shared Neighborhood Hits	143
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

GOGA5_HUMAN
NC score	0.078811 (rank : 311)	θ value	θ > 10 (rank : 660)
Query Neighborhood Hits	455	Target Neighborhood Hits	1168	Shared Neighborhood Hits	128
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

CK5P2_HUMAN
NC score	0.078753 (rank : 312)	θ value	θ > 10 (rank : 571)
Query Neighborhood Hits	455	Target Neighborhood Hits	1433	Shared Neighborhood Hits	160
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

BRE1B_HUMAN
NC score	0.078701 (rank : 313)	θ value	1.06291 (rank : 179)
Query Neighborhood Hits	455	Target Neighborhood Hits	1040	Shared Neighborhood Hits	110
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

HMMR_HUMAN
NC score	0.078658 (rank : 314)	θ value	4.03905 (rank : 311)
Query Neighborhood Hits	455	Target Neighborhood Hits	1082	Shared Neighborhood Hits	118
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

CDN1C_HUMAN
NC score	0.078595 (rank : 315)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	455	Target Neighborhood Hits	168	Shared Neighborhood Hits	42
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

VAV3_HUMAN
NC score	0.078501 (rank : 316)	θ value	θ > 10 (rank : 1003)
Query Neighborhood Hits	455	Target Neighborhood Hits	398	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

GOGA3_MOUSE
NC score	0.078461 (rank : 317)	θ value	8.99809 (rank : 426)
Query Neighborhood Hits	455	Target Neighborhood Hits	1437	Shared Neighborhood Hits	134
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

MY18A_HUMAN
NC score	0.078393 (rank : 318)	θ value	θ > 10 (rank : 772)
Query Neighborhood Hits	455	Target Neighborhood Hits	1929	Shared Neighborhood Hits	174
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MADCA_HUMAN
NC score	0.078294 (rank : 319)	θ value	3.0926 (rank : 278)
Query Neighborhood Hits	455	Target Neighborhood Hits	221	Shared Neighborhood Hits	47
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

WASIP_HUMAN
NC score	0.078279 (rank : 320)	θ value	θ > 10 (rank : 1012)
Query Neighborhood Hits	455	Target Neighborhood Hits	458	Shared Neighborhood Hits	69
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

CP135_HUMAN
NC score	0.078198 (rank : 321)	θ value	θ > 10 (rank : 585)
Query Neighborhood Hits	455	Target Neighborhood Hits	1290	Shared Neighborhood Hits	128
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

GOGA3_HUMAN
NC score	0.078083 (rank : 322)	θ value	θ > 10 (rank : 657)
Query Neighborhood Hits	455	Target Neighborhood Hits	1317	Shared Neighborhood Hits	146
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

HMMR_MOUSE
NC score	0.078076 (rank : 323)	θ value	θ > 10 (rank : 678)
Query Neighborhood Hits	455	Target Neighborhood Hits	1178	Shared Neighborhood Hits	122
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

VAV3_MOUSE
NC score	0.077845 (rank : 324)	θ value	θ > 10 (rank : 1004)
Query Neighborhood Hits	455	Target Neighborhood Hits	404	Shared Neighborhood Hits	84
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

TARA_MOUSE
NC score	0.077777 (rank : 325)	θ value	θ > 10 (rank : 960)
Query Neighborhood Hits	455	Target Neighborhood Hits	1133	Shared Neighborhood Hits	161
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

HRX_HUMAN
NC score	0.077713 (rank : 326)	θ value	0.279714 (rank : 114)
Query Neighborhood Hits	455	Target Neighborhood Hits	825	Shared Neighborhood Hits	104
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

CASP_HUMAN
NC score	0.077606 (rank : 327)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	455	Target Neighborhood Hits	1131	Shared Neighborhood Hits	135
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

RGS3_HUMAN
NC score	0.077503 (rank : 328)	θ value	θ > 10 (rank : 880)
Query Neighborhood Hits	455	Target Neighborhood Hits	1375	Shared Neighborhood Hits	174
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

NCOR2_HUMAN
NC score	0.077498 (rank : 329)	θ value	θ > 10 (rank : 799)
Query Neighborhood Hits	455	Target Neighborhood Hits	870	Shared Neighborhood Hits	129
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

K1210_HUMAN
NC score	0.077172 (rank : 330)	θ value	0.365318 (rank : 123)
Query Neighborhood Hits	455	Target Neighborhood Hits	219	Shared Neighborhood Hits	37
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

GOGA4_MOUSE
NC score	0.077126 (rank : 331)	θ value	θ > 10 (rank : 659)
Query Neighborhood Hits	455	Target Neighborhood Hits	1939	Shared Neighborhood Hits	172
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

PIBF1_HUMAN
NC score	0.077075 (rank : 332)	θ value	θ > 10 (rank : 839)
Query Neighborhood Hits	455	Target Neighborhood Hits	1041	Shared Neighborhood Hits	124
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

TRHY_HUMAN
NC score	0.076984 (rank : 333)	θ value	1.06291 (rank : 198)
Query Neighborhood Hits	455	Target Neighborhood Hits	1385	Shared Neighborhood Hits	122
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

PLCG1_HUMAN
NC score	0.076968 (rank : 334)	θ value	θ > 10 (rank : 842)
Query Neighborhood Hits	455	Target Neighborhood Hits	293	Shared Neighborhood Hits	76
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

CCD11_HUMAN
NC score	0.076954 (rank : 335)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	455	Target Neighborhood Hits	822	Shared Neighborhood Hits	102
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

MAP1B_HUMAN
NC score	0.076876 (rank : 336)	θ value	θ > 10 (rank : 747)
Query Neighborhood Hits	455	Target Neighborhood Hits	903	Shared Neighborhood Hits	132
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

RAD50_HUMAN
NC score	0.076862 (rank : 337)	θ value	θ > 10 (rank : 861)
Query Neighborhood Hits	455	Target Neighborhood Hits	1317	Shared Neighborhood Hits	131
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

SPTA1_MOUSE
NC score	0.076854 (rank : 338)	θ value	θ > 10 (rank : 931)
Query Neighborhood Hits	455	Target Neighborhood Hits	675	Shared Neighborhood Hits	132
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

CASL_MOUSE
NC score	0.076840 (rank : 339)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	455	Target Neighborhood Hits	225	Shared Neighborhood Hits	81
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

GCC2_HUMAN
NC score	0.076796 (rank : 340)	θ value	θ > 10 (rank : 648)
Query Neighborhood Hits	455	Target Neighborhood Hits	1558	Shared Neighborhood Hits	151
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

CASL_HUMAN
NC score	0.076792 (rank : 341)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	455	Target Neighborhood Hits	259	Shared Neighborhood Hits	81
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

RBP24_HUMAN
NC score	0.076762 (rank : 342)	θ value	θ > 10 (rank : 871)
Query Neighborhood Hits	455	Target Neighborhood Hits	1559	Shared Neighborhood Hits	150
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

CING_MOUSE
NC score	0.076735 (rank : 343)	θ value	θ > 10 (rank : 562)
Query Neighborhood Hits	455	Target Neighborhood Hits	1432	Shared Neighborhood Hits	135
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CCD11_MOUSE
NC score	0.076640 (rank : 344)	θ value	3.0926 (rank : 267)
Query Neighborhood Hits	455	Target Neighborhood Hits	498	Shared Neighborhood Hits	74
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

RAD50_MOUSE
NC score	0.076638 (rank : 345)	θ value	θ > 10 (rank : 862)
Query Neighborhood Hits	455	Target Neighborhood Hits	1366	Shared Neighborhood Hits	137
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

CF010_HUMAN
NC score	0.076637 (rank : 346)	θ value	0.62314 (rank : 145)
Query Neighborhood Hits	455	Target Neighborhood Hits	329	Shared Neighborhood Hits	53
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

TMF1_HUMAN
NC score	0.076622 (rank : 347)	θ value	θ > 10 (rank : 973)
Query Neighborhood Hits	455	Target Neighborhood Hits	987	Shared Neighborhood Hits	122
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

DESP_HUMAN
NC score	0.076524 (rank : 348)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	455	Target Neighborhood Hits	1470	Shared Neighborhood Hits	144
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

EEA1_HUMAN
NC score	0.076465 (rank : 349)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	455	Target Neighborhood Hits	1796	Shared Neighborhood Hits	158
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

SAPS1_HUMAN
NC score	0.076445 (rank : 350)	θ value	1.81305 (rank : 226)
Query Neighborhood Hits	455	Target Neighborhood Hits	704	Shared Neighborhood Hits	125
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

CCD41_MOUSE
NC score	0.076432 (rank : 351)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	455	Target Neighborhood Hits	1399	Shared Neighborhood Hits	137
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

FMNL_HUMAN
NC score	0.076422 (rank : 352)	θ value	0.813845 (rank : 164)
Query Neighborhood Hits	455	Target Neighborhood Hits	529	Shared Neighborhood Hits	93
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

TACC1_MOUSE
NC score	0.076394 (rank : 353)	θ value	θ > 10 (rank : 953)
Query Neighborhood Hits	455	Target Neighborhood Hits	667	Shared Neighborhood Hits	111
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

CF060_HUMAN
NC score	0.076162 (rank : 354)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	455	Target Neighborhood Hits	1270	Shared Neighborhood Hits	131
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

CCD39_MOUSE
NC score	0.076144 (rank : 355)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	455	Target Neighborhood Hits	1026	Shared Neighborhood Hits	122
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CBP_HUMAN
NC score	0.076103 (rank : 356)	θ value	3.0926 (rank : 266)
Query Neighborhood Hits	455	Target Neighborhood Hits	941	Shared Neighborhood Hits	122
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

REST_HUMAN
NC score	0.075938 (rank : 357)	θ value	θ > 10 (rank : 875)
Query Neighborhood Hits	455	Target Neighborhood Hits	1605	Shared Neighborhood Hits	158
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

TPM1_MOUSE
NC score	0.075889 (rank : 358)	θ value	θ > 10 (rank : 978)
Query Neighborhood Hits	455	Target Neighborhood Hits	729	Shared Neighborhood Hits	99
SwissProt Accessions	P58771, P02558, P19354, P46902, P99034	Gene names	Tpm1, Tpm-1, Tpma
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

KI67_HUMAN
NC score	0.075861 (rank : 359)	θ value	θ > 10 (rank : 706)
Query Neighborhood Hits	455	Target Neighborhood Hits	581	Shared Neighborhood Hits	98
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

K0555_HUMAN
NC score	0.075859 (rank : 360)	θ value	θ > 10 (rank : 701)
Query Neighborhood Hits	455	Target Neighborhood Hits	880	Shared Neighborhood Hits	110
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

NUMA1_HUMAN
NC score	0.075815 (rank : 361)	θ value	θ > 10 (rank : 820)
Query Neighborhood Hits	455	Target Neighborhood Hits	1523	Shared Neighborhood Hits	156
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

TPM1_HUMAN
NC score	0.075767 (rank : 362)	θ value	θ > 10 (rank : 977)
Query Neighborhood Hits	455	Target Neighborhood Hits	716	Shared Neighborhood Hits	97
SwissProt Accessions	P09493, P09494, P10469, Q86W64, Q96IK2, Q9UCY9	Gene names	TPM1, TMSA
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

PRAX_HUMAN
NC score	0.075761 (rank : 363)	θ value	θ > 10 (rank : 849)
Query Neighborhood Hits	455	Target Neighborhood Hits	215	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

EP15R_MOUSE
NC score	0.075684 (rank : 364)	θ value	θ > 10 (rank : 626)
Query Neighborhood Hits	455	Target Neighborhood Hits	1135	Shared Neighborhood Hits	132
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

EP15R_HUMAN
NC score	0.075399 (rank : 365)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	455	Target Neighborhood Hits	1083	Shared Neighborhood Hits	127
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

JIP3_HUMAN
NC score	0.075184 (rank : 366)	θ value	1.38821 (rank : 201)
Query Neighborhood Hits	455	Target Neighborhood Hits	1039	Shared Neighborhood Hits	156
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

MAP1B_MOUSE
NC score	0.075177 (rank : 367)	θ value	θ > 10 (rank : 748)
Query Neighborhood Hits	455	Target Neighborhood Hits	977	Shared Neighborhood Hits	148
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

AZI1_HUMAN
NC score	0.075095 (rank : 368)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	455	Target Neighborhood Hits	1000	Shared Neighborhood Hits	115
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

GAS8_HUMAN
NC score	0.075076 (rank : 369)	θ value	θ > 10 (rank : 644)
Query Neighborhood Hits	455	Target Neighborhood Hits	819	Shared Neighborhood Hits	103
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

PRB4S_HUMAN
NC score	0.075053 (rank : 370)	θ value	θ > 10 (rank : 852)
Query Neighborhood Hits	455	Target Neighborhood Hits	330	Shared Neighborhood Hits	58
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

CBP_MOUSE
NC score	0.075026 (rank : 371)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	455	Target Neighborhood Hits	1051	Shared Neighborhood Hits	139
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CE290_HUMAN
NC score	0.074968 (rank : 372)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	455	Target Neighborhood Hits	1553	Shared Neighborhood Hits	140
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

SMC3_MOUSE
NC score	0.074954 (rank : 373)	θ value	θ > 10 (rank : 919)
Query Neighborhood Hits	455	Target Neighborhood Hits	1187	Shared Neighborhood Hits	124
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SMC3_HUMAN
NC score	0.074924 (rank : 374)	θ value	θ > 10 (rank : 918)
Query Neighborhood Hits	455	Target Neighborhood Hits	1186	Shared Neighborhood Hits	124
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

WIRE_HUMAN
NC score	0.074910 (rank : 375)	θ value	5.27518 (rank : 365)
Query Neighborhood Hits	455	Target Neighborhood Hits	329	Shared Neighborhood Hits	53
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

CEP63_HUMAN
NC score	0.074825 (rank : 376)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	455	Target Neighborhood Hits	1005	Shared Neighborhood Hits	122
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

MBD6_HUMAN
NC score	0.074626 (rank : 377)	θ value	θ > 10 (rank : 754)
Query Neighborhood Hits	455	Target Neighborhood Hits	349	Shared Neighborhood Hits	62
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

CT2NL_MOUSE
NC score	0.074543 (rank : 378)	θ value	8.99809 (rank : 419)
Query Neighborhood Hits	455	Target Neighborhood Hits	902	Shared Neighborhood Hits	125
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CCD96_MOUSE
NC score	0.074531 (rank : 379)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	455	Target Neighborhood Hits	704	Shared Neighborhood Hits	106
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

OFD1_HUMAN
NC score	0.074519 (rank : 380)	θ value	θ > 10 (rank : 821)
Query Neighborhood Hits	455	Target Neighborhood Hits	753	Shared Neighborhood Hits	95
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

KTN1_MOUSE
NC score	0.074372 (rank : 381)	θ value	θ > 10 (rank : 715)
Query Neighborhood Hits	455	Target Neighborhood Hits	1324	Shared Neighborhood Hits	139
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

CP250_MOUSE
NC score	0.074354 (rank : 382)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	455	Target Neighborhood Hits	1583	Shared Neighborhood Hits	154
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

REST_MOUSE
NC score	0.074238 (rank : 383)	θ value	θ > 10 (rank : 876)
Query Neighborhood Hits	455	Target Neighborhood Hits	1506	Shared Neighborhood Hits	143
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

SRRM2_HUMAN
NC score	0.074187 (rank : 384)	θ value	θ > 10 (rank : 938)
Query Neighborhood Hits	455	Target Neighborhood Hits	1296	Shared Neighborhood Hits	146
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

PO121_MOUSE
NC score	0.073873 (rank : 385)	θ value	1.06291 (rank : 192)
Query Neighborhood Hits	455	Target Neighborhood Hits	345	Shared Neighborhood Hits	51
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

M3K11_HUMAN
NC score	0.073849 (rank : 386)	θ value	0.0113563 (rank : 45)
Query Neighborhood Hits	455	Target Neighborhood Hits	1136	Shared Neighborhood Hits	129
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

ARHG4_MOUSE
NC score	0.073837 (rank : 387)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	455	Target Neighborhood Hits	185	Shared Neighborhood Hits	57
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

LARP4_MOUSE
NC score	0.073795 (rank : 388)	θ value	θ > 10 (rank : 718)
Query Neighborhood Hits	455	Target Neighborhood Hits	260	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

GOGA2_MOUSE
NC score	0.073792 (rank : 389)	θ value	θ > 10 (rank : 656)
Query Neighborhood Hits	455	Target Neighborhood Hits	944	Shared Neighborhood Hits	117
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

RTN4_HUMAN
NC score	0.073560 (rank : 390)	θ value	1.81305 (rank : 225)
Query Neighborhood Hits	455	Target Neighborhood Hits	357	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

MLL3_HUMAN
NC score	0.073543 (rank : 391)	θ value	θ > 10 (rank : 761)
Query Neighborhood Hits	455	Target Neighborhood Hits	1644	Shared Neighborhood Hits	179
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

DMD_HUMAN
NC score	0.073514 (rank : 392)	θ value	6.88961 (rank : 377)
Query Neighborhood Hits	455	Target Neighborhood Hits	1135	Shared Neighborhood Hits	119
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

GRIN1_HUMAN
NC score	0.073432 (rank : 393)	θ value	θ > 10 (rank : 669)
Query Neighborhood Hits	455	Target Neighborhood Hits	681	Shared Neighborhood Hits	93
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

CN145_HUMAN
NC score	0.073407 (rank : 394)	θ value	θ > 10 (rank : 576)
Query Neighborhood Hits	455	Target Neighborhood Hits	1196	Shared Neighborhood Hits	125
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

KMHN1_MOUSE
NC score	0.073387 (rank : 395)	θ value	8.99809 (rank : 429)
Query Neighborhood Hits	455	Target Neighborhood Hits	949	Shared Neighborhood Hits	106
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

CCD37_HUMAN
NC score	0.073387 (rank : 396)	θ value	0.813845 (rank : 162)
Query Neighborhood Hits	455	Target Neighborhood Hits	248	Shared Neighborhood Hits	50
SwissProt Accessions	Q494V2, Q494V1, Q494V4, Q8N838	Gene names	CCDC37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 37.

TACC3_MOUSE
NC score	0.073335 (rank : 397)	θ value	θ > 10 (rank : 955)
Query Neighborhood Hits	455	Target Neighborhood Hits	607	Shared Neighborhood Hits	95
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

OPTN_MOUSE
NC score	0.073306 (rank : 398)	θ value	θ > 10 (rank : 824)
Query Neighborhood Hits	455	Target Neighborhood Hits	1120	Shared Neighborhood Hits	124
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

NU214_HUMAN
NC score	0.073268 (rank : 399)	θ value	θ > 10 (rank : 818)
Query Neighborhood Hits	455	Target Neighborhood Hits	657	Shared Neighborhood Hits	95
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

CROCC_MOUSE
NC score	0.073239 (rank : 400)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	455	Target Neighborhood Hits	1460	Shared Neighborhood Hits	146
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CASC3_MOUSE
NC score	0.073114 (rank : 401)	θ value	0.813845 (rank : 160)
Query Neighborhood Hits	455	Target Neighborhood Hits	333	Shared Neighborhood Hits	70
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

GOGA2_HUMAN
NC score	0.073067 (rank : 402)	θ value	2.36792 (rank : 242)
Query Neighborhood Hits	455	Target Neighborhood Hits	856	Shared Neighborhood Hits	111
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

TPM4_MOUSE
NC score	0.072996 (rank : 403)	θ value	θ > 10 (rank : 982)
Query Neighborhood Hits	455	Target Neighborhood Hits	703	Shared Neighborhood Hits	97
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

INVO_HUMAN
NC score	0.072955 (rank : 404)	θ value	θ > 10 (rank : 695)
Query Neighborhood Hits	455	Target Neighborhood Hits	636	Shared Neighborhood Hits	113
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

SDCG8_HUMAN
NC score	0.072920 (rank : 405)	θ value	θ > 10 (rank : 901)
Query Neighborhood Hits	455	Target Neighborhood Hits	1002	Shared Neighborhood Hits	117
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

CCD41_HUMAN
NC score	0.072910 (rank : 406)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	455	Target Neighborhood Hits	1139	Shared Neighborhood Hits	121
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

IFT81_MOUSE
NC score	0.072898 (rank : 407)	θ value	θ > 10 (rank : 694)
Query Neighborhood Hits	455	Target Neighborhood Hits	959	Shared Neighborhood Hits	111
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

ACINU_HUMAN
NC score	0.072898 (rank : 408)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	455	Target Neighborhood Hits	828	Shared Neighborhood Hits	129
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

HOOK1_MOUSE
NC score	0.072767 (rank : 409)	θ value	θ > 10 (rank : 681)
Query Neighborhood Hits	455	Target Neighborhood Hits	910	Shared Neighborhood Hits	116
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

TAXB1_MOUSE
NC score	0.072744 (rank : 410)	θ value	θ > 10 (rank : 962)
Query Neighborhood Hits	455	Target Neighborhood Hits	886	Shared Neighborhood Hits	105
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

RAPH1_HUMAN
NC score	0.072717 (rank : 411)	θ value	θ > 10 (rank : 865)
Query Neighborhood Hits	455	Target Neighborhood Hits	593	Shared Neighborhood Hits	89
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

CYLN2_HUMAN
NC score	0.072496 (rank : 412)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	455	Target Neighborhood Hits	1004	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

SPRR3_HUMAN
NC score	0.072408 (rank : 413)	θ value	θ > 10 (rank : 929)
Query Neighborhood Hits	455	Target Neighborhood Hits	102	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

CABIN_HUMAN
NC score	0.072277 (rank : 414)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	455	Target Neighborhood Hits	490	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

RABE1_HUMAN
NC score	0.072203 (rank : 415)	θ value	θ > 10 (rank : 857)
Query Neighborhood Hits	455	Target Neighborhood Hits	1104	Shared Neighborhood Hits	127
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

CCD39_HUMAN
NC score	0.072197 (rank : 416)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	455	Target Neighborhood Hits	868	Shared Neighborhood Hits	107
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

PRB3_HUMAN
NC score	0.072196 (rank : 417)	θ value	θ > 10 (rank : 851)
Query Neighborhood Hits	455	Target Neighborhood Hits	318	Shared Neighborhood Hits	52
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

WIRE_MOUSE
NC score	0.072160 (rank : 418)	θ value	4.03905 (rank : 325)
Query Neighborhood Hits	455	Target Neighborhood Hits	310	Shared Neighborhood Hits	50
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

RB6I2_HUMAN
NC score	0.072148 (rank : 419)	θ value	θ > 10 (rank : 866)
Query Neighborhood Hits	455	Target Neighborhood Hits	1584	Shared Neighborhood Hits	146
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

CT2NL_HUMAN
NC score	0.071946 (rank : 420)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	455	Target Neighborhood Hits	1059	Shared Neighborhood Hits	129
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

ENAH_HUMAN
NC score	0.071886 (rank : 421)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	455	Target Neighborhood Hits	784	Shared Neighborhood Hits	118
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

WASIP_MOUSE
NC score	0.071757 (rank : 422)	θ value	θ > 10 (rank : 1013)
Query Neighborhood Hits	455	Target Neighborhood Hits	392	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

NFM_MOUSE
NC score	0.071724 (rank : 423)	θ value	0.365318 (rank : 126)
Query Neighborhood Hits	455	Target Neighborhood Hits	1159	Shared Neighborhood Hits	144
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

ARMX2_HUMAN
NC score	0.071616 (rank : 424)	θ value	0.163984 (rank : 97)
Query Neighborhood Hits	455	Target Neighborhood Hits	134	Shared Neighborhood Hits	26
SwissProt Accessions	Q7L311, O60267, Q5H9D9	Gene names	ARMCX2, ALEX2, KIAA0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2 (Protein ALEX2) (ARM protein lost in epithelial cancers on chromosome X 2).

CIC_HUMAN
NC score	0.071562 (rank : 425)	θ value	8.99809 (rank : 418)
Query Neighborhood Hits	455	Target Neighborhood Hits	992	Shared Neighborhood Hits	131
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CJ118_MOUSE
NC score	0.071554 (rank : 426)	θ value	θ > 10 (rank : 568)
Query Neighborhood Hits	455	Target Neighborhood Hits	1132	Shared Neighborhood Hits	117
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

EP300_HUMAN
NC score	0.071360 (rank : 427)	θ value	1.06291 (rank : 185)
Query Neighborhood Hits	455	Target Neighborhood Hits	821	Shared Neighborhood Hits	103
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

RB6I2_MOUSE
NC score	0.071263 (rank : 428)	θ value	θ > 10 (rank : 867)
Query Neighborhood Hits	455	Target Neighborhood Hits	1433	Shared Neighborhood Hits	137
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

LRRF2_HUMAN
NC score	0.071143 (rank : 429)	θ value	θ > 10 (rank : 736)
Query Neighborhood Hits	455	Target Neighborhood Hits	791	Shared Neighborhood Hits	105
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

BCAS1_HUMAN
NC score	0.071012 (rank : 430)	θ value	0.47712 (rank : 131)
Query Neighborhood Hits	455	Target Neighborhood Hits	133	Shared Neighborhood Hits	33
SwissProt Accessions	O75363, Q68CZ3	Gene names	BCAS1, AIBC1, NABC1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 (Novel amplified in breast cancer 1) (Amplified and overexpressed in breast cancer).

CE152_HUMAN
NC score	0.070963 (rank : 431)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	455	Target Neighborhood Hits	976	Shared Neighborhood Hits	112
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

NIN_HUMAN
NC score	0.070819 (rank : 432)	θ value	θ > 10 (rank : 809)
Query Neighborhood Hits	455	Target Neighborhood Hits	1416	Shared Neighborhood Hits	134
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

IFT74_HUMAN
NC score	0.070722 (rank : 433)	θ value	θ > 10 (rank : 691)
Query Neighborhood Hits	455	Target Neighborhood Hits	949	Shared Neighborhood Hits	103
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

SHAN2_MOUSE
NC score	0.070716 (rank : 434)	θ value	θ > 10 (rank : 915)
Query Neighborhood Hits	455	Target Neighborhood Hits	446	Shared Neighborhood Hits	91
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

RABE1_MOUSE
NC score	0.070563 (rank : 435)	θ value	θ > 10 (rank : 858)
Query Neighborhood Hits	455	Target Neighborhood Hits	1105	Shared Neighborhood Hits	126
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

K1802_HUMAN
NC score	0.070550 (rank : 436)	θ value	θ > 10 (rank : 705)
Query Neighborhood Hits	455	Target Neighborhood Hits	1378	Shared Neighborhood Hits	135
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

HOOK1_HUMAN
NC score	0.070537 (rank : 437)	θ value	θ > 10 (rank : 680)
Query Neighborhood Hits	455	Target Neighborhood Hits	942	Shared Neighborhood Hits	117
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

IFT81_HUMAN
NC score	0.070514 (rank : 438)	θ value	θ > 10 (rank : 693)
Query Neighborhood Hits	455	Target Neighborhood Hits	893	Shared Neighborhood Hits	109
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

LIPA1_HUMAN
NC score	0.070510 (rank : 439)	θ value	8.99809 (rank : 430)
Query Neighborhood Hits	455	Target Neighborhood Hits	1294	Shared Neighborhood Hits	141
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

SMC4_HUMAN
NC score	0.070478 (rank : 440)	θ value	θ > 10 (rank : 920)
Query Neighborhood Hits	455	Target Neighborhood Hits	937	Shared Neighborhood Hits	112
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

LUZP1_MOUSE
NC score	0.070393 (rank : 441)	θ value	θ > 10 (rank : 739)
Query Neighborhood Hits	455	Target Neighborhood Hits	940	Shared Neighborhood Hits	116
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

GOGA6_HUMAN
NC score	0.070239 (rank : 442)	θ value	θ > 10 (rank : 661)
Query Neighborhood Hits	455	Target Neighborhood Hits	1007	Shared Neighborhood Hits	114
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

CYTSA_HUMAN
NC score	0.070115 (rank : 443)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	455	Target Neighborhood Hits	1138	Shared Neighborhood Hits	146
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

EP15_HUMAN
NC score	0.069896 (rank : 444)	θ value	θ > 10 (rank : 627)
Query Neighborhood Hits	455	Target Neighborhood Hits	1021	Shared Neighborhood Hits	121
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

MYH14_MOUSE
NC score	0.069786 (rank : 445)	θ value	6.88961 (rank : 391)
Query Neighborhood Hits	455	Target Neighborhood Hits	1225	Shared Neighborhood Hits	129
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

SNPC4_HUMAN
NC score	0.069745 (rank : 446)	θ value	θ > 10 (rank : 922)
Query Neighborhood Hits	455	Target Neighborhood Hits	589	Shared Neighborhood Hits	119
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

TAXB1_HUMAN
NC score	0.069695 (rank : 447)	θ value	θ > 10 (rank : 961)
Query Neighborhood Hits	455	Target Neighborhood Hits	829	Shared Neighborhood Hits	92
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

TXND2_MOUSE
NC score	0.069665 (rank : 448)	θ value	θ > 10 (rank : 997)
Query Neighborhood Hits	455	Target Neighborhood Hits	828	Shared Neighborhood Hits	112
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

CUTL2_HUMAN
NC score	0.069645 (rank : 449)	θ value	1.06291 (rank : 183)
Query Neighborhood Hits	455	Target Neighborhood Hits	906	Shared Neighborhood Hits	115
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

AN30A_HUMAN
NC score	0.069531 (rank : 450)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	455	Target Neighborhood Hits	1119	Shared Neighborhood Hits	139
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ZAN_MOUSE
NC score	0.069517 (rank : 451)	θ value	1.43324e-05 (rank : 10)
Query Neighborhood Hits	455	Target Neighborhood Hits	808	Shared Neighborhood Hits	43
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

NUF2_MOUSE
NC score	0.069473 (rank : 452)	θ value	θ > 10 (rank : 819)
Query Neighborhood Hits	455	Target Neighborhood Hits	585	Shared Neighborhood Hits	91
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

PEPL_HUMAN
NC score	0.069421 (rank : 453)	θ value	5.27518 (rank : 349)
Query Neighborhood Hits	455	Target Neighborhood Hits	1141	Shared Neighborhood Hits	120
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

ES8L3_HUMAN
NC score	0.069392 (rank : 454)	θ value	θ > 10 (rank : 634)
Query Neighborhood Hits	455	Target Neighborhood Hits	206	Shared Neighborhood Hits	61
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

BRD4_MOUSE
NC score	0.069330 (rank : 455)	θ value	1.81305 (rank : 214)
Query Neighborhood Hits	455	Target Neighborhood Hits	845	Shared Neighborhood Hits	122
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

ERC2_HUMAN
NC score	0.069324 (rank : 456)	θ value	θ > 10 (rank : 629)
Query Neighborhood Hits	455	Target Neighborhood Hits	1156	Shared Neighborhood Hits	125
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

CYLN2_MOUSE
NC score	0.069302 (rank : 457)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	455	Target Neighborhood Hits	1002	Shared Neighborhood Hits	115
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

NIN_MOUSE
NC score	0.069210 (rank : 458)	θ value	θ > 10 (rank : 810)
Query Neighborhood Hits	455	Target Neighborhood Hits	1376	Shared Neighborhood Hits	139
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

NEMO_HUMAN
NC score	0.069161 (rank : 459)	θ value	θ > 10 (rank : 805)
Query Neighborhood Hits	455	Target Neighborhood Hits	820	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

RHG26_HUMAN
NC score	0.069011 (rank : 460)	θ value	θ > 10 (rank : 882)
Query Neighborhood Hits	455	Target Neighborhood Hits	281	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

CF152_HUMAN
NC score	0.068984 (rank : 461)	θ value	θ > 10 (rank : 556)
Query Neighborhood Hits	455	Target Neighborhood Hits	704	Shared Neighborhood Hits	91
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

PO121_HUMAN
NC score	0.068972 (rank : 462)	θ value	θ > 10 (rank : 846)
Query Neighborhood Hits	455	Target Neighborhood Hits	344	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

CCHCR_MOUSE
NC score	0.068953 (rank : 463)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	455	Target Neighborhood Hits	932	Shared Neighborhood Hits	110
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

GRAP1_MOUSE
NC score	0.068815 (rank : 464)	θ value	θ > 10 (rank : 664)
Query Neighborhood Hits	455	Target Neighborhood Hits	1234	Shared Neighborhood Hits	137
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

SFPQ_MOUSE
NC score	0.068804 (rank : 465)	θ value	θ > 10 (rank : 910)
Query Neighborhood Hits	455	Target Neighborhood Hits	958	Shared Neighborhood Hits	116
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

MAP2_MOUSE
NC score	0.068719 (rank : 466)	θ value	1.81305 (rank : 219)
Query Neighborhood Hits	455	Target Neighborhood Hits	342	Shared Neighborhood Hits	76
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

TACC1_HUMAN
NC score	0.068501 (rank : 467)	θ value	θ > 10 (rank : 952)
Query Neighborhood Hits	455	Target Neighborhood Hits	597	Shared Neighborhood Hits	93
SwissProt Accessions	O75410, Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2, Q8NEY7, Q9UPP9	Gene names	TACC1, KIAA1103
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 1 (Taxin 1) (Gastric cancer antigen Ga55).

MYH8_HUMAN
NC score	0.068454 (rank : 468)	θ value	θ > 10 (rank : 783)
Query Neighborhood Hits	455	Target Neighborhood Hits	1610	Shared Neighborhood Hits	159
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

CCD91_HUMAN
NC score	0.068406 (rank : 469)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	455	Target Neighborhood Hits	868	Shared Neighborhood Hits	113
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

GAS8_MOUSE
NC score	0.068398 (rank : 470)	θ value	θ > 10 (rank : 645)
Query Neighborhood Hits	455	Target Neighborhood Hits	622	Shared Neighborhood Hits	88
SwissProt Accessions	Q60779, Q99L71	Gene names	Gas8, Gas11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

M3K10_HUMAN
NC score	0.068397 (rank : 471)	θ value	0.00228821 (rank : 26)
Query Neighborhood Hits	455	Target Neighborhood Hits	1071	Shared Neighborhood Hits	106
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

ERC2_MOUSE
NC score	0.068376 (rank : 472)	θ value	θ > 10 (rank : 630)
Query Neighborhood Hits	455	Target Neighborhood Hits	1166	Shared Neighborhood Hits	123
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

CROCC_HUMAN
NC score	0.068323 (rank : 473)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	455	Target Neighborhood Hits	1409	Shared Neighborhood Hits	142
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

TXLNA_MOUSE
NC score	0.068314 (rank : 474)	θ value	θ > 10 (rank : 992)
Query Neighborhood Hits	455	Target Neighborhood Hits	846	Shared Neighborhood Hits	111
SwissProt Accessions	Q6PAM1, Q6P1E5	Gene names	Txlna, Txln
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

CALD1_HUMAN
NC score	0.068202 (rank : 475)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	455	Target Neighborhood Hits	959	Shared Neighborhood Hits	104
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

SMC4_MOUSE
NC score	0.068139 (rank : 476)	θ value	θ > 10 (rank : 921)
Query Neighborhood Hits	455	Target Neighborhood Hits	830	Shared Neighborhood Hits	104
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

HIP1_HUMAN
NC score	0.068121 (rank : 477)	θ value	θ > 10 (rank : 677)
Query Neighborhood Hits	455	Target Neighborhood Hits	1016	Shared Neighborhood Hits	118
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

BPAEA_MOUSE
NC score	0.068113 (rank : 478)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	455	Target Neighborhood Hits	1480	Shared Neighborhood Hits	139
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

PSL1_HUMAN
NC score	0.068005 (rank : 479)	θ value	θ > 10 (rank : 856)
Query Neighborhood Hits	455	Target Neighborhood Hits	650	Shared Neighborhood Hits	120
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

HOOK2_MOUSE
NC score	0.067951 (rank : 480)	θ value	θ > 10 (rank : 683)
Query Neighborhood Hits	455	Target Neighborhood Hits	736	Shared Neighborhood Hits	99
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

LIPA2_MOUSE
NC score	0.067928 (rank : 481)	θ value	θ > 10 (rank : 721)
Query Neighborhood Hits	455	Target Neighborhood Hits	1282	Shared Neighborhood Hits	140
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

OPTN_HUMAN
NC score	0.067864 (rank : 482)	θ value	θ > 10 (rank : 823)
Query Neighborhood Hits	455	Target Neighborhood Hits	827	Shared Neighborhood Hits	111
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

BAG3_MOUSE
NC score	0.067843 (rank : 483)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	455	Target Neighborhood Hits	513	Shared Neighborhood Hits	95
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

BPTF_HUMAN
NC score	0.067826 (rank : 484)	θ value	0.813845 (rank : 159)
Query Neighborhood Hits	455	Target Neighborhood Hits	786	Shared Neighborhood Hits	115
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

MYO5C_HUMAN
NC score	0.067802 (rank : 485)	θ value	θ > 10 (rank : 791)
Query Neighborhood Hits	455	Target Neighborhood Hits	1206	Shared Neighborhood Hits	130
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

RERE_MOUSE
NC score	0.067750 (rank : 486)	θ value	θ > 10 (rank : 874)
Query Neighborhood Hits	455	Target Neighborhood Hits	785	Shared Neighborhood Hits	99
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

MOT8_HUMAN
NC score	0.067643 (rank : 487)	θ value	0.0330416 (rank : 59)
Query Neighborhood Hits	455	Target Neighborhood Hits	92	Shared Neighborhood Hits	16
SwissProt Accessions	P36021, Q7Z797	Gene names	SLC16A2, MCT8, XPCT
Domain Architecture	No domain graphic available
Description	Monocarboxylate transporter 8 (MCT 8) (MCT 7) (Solute carrier family 16 member 2) (X-linked PEST-containing transporter).

SYNE2_HUMAN
NC score	0.067599 (rank : 488)	θ value	3.0926 (rank : 291)
Query Neighborhood Hits	455	Target Neighborhood Hits	1323	Shared Neighborhood Hits	140
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

TPM3_HUMAN
NC score	0.067590 (rank : 489)	θ value	θ > 10 (rank : 979)
Query Neighborhood Hits	455	Target Neighborhood Hits	689	Shared Neighborhood Hits	84
SwissProt Accessions	P06753, P12324, Q969Q2, Q9NQH8	Gene names	TPM3
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma) (hTM5).

IFT74_MOUSE
NC score	0.067525 (rank : 490)	θ value	θ > 10 (rank : 692)
Query Neighborhood Hits	455	Target Neighborhood Hits	939	Shared Neighborhood Hits	98
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

PININ_MOUSE
NC score	0.067511 (rank : 491)	θ value	θ > 10 (rank : 841)
Query Neighborhood Hits	455	Target Neighborhood Hits	777	Shared Neighborhood Hits	111
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

ANM2_HUMAN
NC score	0.067425 (rank : 492)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	455	Target Neighborhood Hits	175	Shared Neighborhood Hits	66
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

NEUM_MOUSE
NC score	0.067369 (rank : 493)	θ value	1.81305 (rank : 224)
Query Neighborhood Hits	455	Target Neighborhood Hits	149	Shared Neighborhood Hits	34
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

TPM3_MOUSE
NC score	0.067277 (rank : 494)	θ value	θ > 10 (rank : 980)
Query Neighborhood Hits	455	Target Neighborhood Hits	676	Shared Neighborhood Hits	85
SwissProt Accessions	P21107, Q09021, Q60606, Q80SW6, Q9EPW3	Gene names	Tpm3, Tpm-5, Tpm5
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma).

MYH13_HUMAN
NC score	0.067185 (rank : 495)	θ value	θ > 10 (rank : 774)
Query Neighborhood Hits	455	Target Neighborhood Hits	1504	Shared Neighborhood Hits	139
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MD1L1_MOUSE
NC score	0.067165 (rank : 496)	θ value	θ > 10 (rank : 756)
Query Neighborhood Hits	455	Target Neighborhood Hits	1001	Shared Neighborhood Hits	112
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

CCD19_HUMAN
NC score	0.067031 (rank : 497)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	455	Target Neighborhood Hits	639	Shared Neighborhood Hits	91
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

BRE1B_MOUSE
NC score	0.067006 (rank : 498)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	455	Target Neighborhood Hits	970	Shared Neighborhood Hits	102
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

CYTSA_MOUSE
NC score	0.066997 (rank : 499)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	455	Target Neighborhood Hits	1104	Shared Neighborhood Hits	132
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

TSC1_HUMAN
NC score	0.066860 (rank : 500)	θ value	θ > 10 (rank : 989)
Query Neighborhood Hits	455	Target Neighborhood Hits	765	Shared Neighborhood Hits	117
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

MYH3_HUMAN
NC score	0.066793 (rank : 501)	θ value	θ > 10 (rank : 779)
Query Neighborhood Hits	455	Target Neighborhood Hits	1660	Shared Neighborhood Hits	153
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

TUFT1_HUMAN
NC score	0.066777 (rank : 502)	θ value	θ > 10 (rank : 990)
Query Neighborhood Hits	455	Target Neighborhood Hits	686	Shared Neighborhood Hits	96
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

ANK2_HUMAN
NC score	0.066735 (rank : 503)	θ value	0.279714 (rank : 112)
Query Neighborhood Hits	455	Target Neighborhood Hits	1615	Shared Neighborhood Hits	188
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

UACA_HUMAN
NC score	0.066682 (rank : 504)	θ value	θ > 10 (rank : 998)
Query Neighborhood Hits	455	Target Neighborhood Hits	1622	Shared Neighborhood Hits	142
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

MRCKB_MOUSE
NC score	0.066682 (rank : 505)	θ value	0.00175202 (rank : 21)
Query Neighborhood Hits	455	Target Neighborhood Hits	2180	Shared Neighborhood Hits	180
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

VCX3_HUMAN
NC score	0.066651 (rank : 506)	θ value	θ > 10 (rank : 1008)
Query Neighborhood Hits	455	Target Neighborhood Hits	105	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

FA47A_HUMAN
NC score	0.066637 (rank : 507)	θ value	θ > 10 (rank : 637)
Query Neighborhood Hits	455	Target Neighborhood Hits	451	Shared Neighborhood Hits	74
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

BICD2_MOUSE
NC score	0.066616 (rank : 508)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	455	Target Neighborhood Hits	864	Shared Neighborhood Hits	103
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BICD2_HUMAN
NC score	0.066596 (rank : 509)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	455	Target Neighborhood Hits	856	Shared Neighborhood Hits	102
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

ZAN_HUMAN
NC score	0.066560 (rank : 510)	θ value	8.99809 (rank : 454)
Query Neighborhood Hits	455	Target Neighborhood Hits	679	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

CCD13_HUMAN
NC score	0.066556 (rank : 511)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	455	Target Neighborhood Hits	721	Shared Neighborhood Hits	95
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

KMHN1_HUMAN
NC score	0.066522 (rank : 512)	θ value	θ > 10 (rank : 711)
Query Neighborhood Hits	455	Target Neighborhood Hits	950	Shared Neighborhood Hits	98
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

MYH8_MOUSE
NC score	0.066519 (rank : 513)	θ value	θ > 10 (rank : 784)
Query Neighborhood Hits	455	Target Neighborhood Hits	1600	Shared Neighborhood Hits	151
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

LCP2_HUMAN
NC score	0.066481 (rank : 514)	θ value	θ > 10 (rank : 719)
Query Neighborhood Hits	455	Target Neighborhood Hits	531	Shared Neighborhood Hits	95
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

CJ118_HUMAN
NC score	0.066466 (rank : 515)	θ value	θ > 10 (rank : 567)
Query Neighborhood Hits	455	Target Neighborhood Hits	937	Shared Neighborhood Hits	108
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

RUFY2_HUMAN
NC score	0.066430 (rank : 516)	θ value	θ > 10 (rank : 893)
Query Neighborhood Hits	455	Target Neighborhood Hits	1208	Shared Neighborhood Hits	123
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

SAS6_MOUSE
NC score	0.066390 (rank : 517)	θ value	θ > 10 (rank : 899)
Query Neighborhood Hits	455	Target Neighborhood Hits	931	Shared Neighborhood Hits	104
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

ANR26_HUMAN
NC score	0.066322 (rank : 518)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	455	Target Neighborhood Hits	1614	Shared Neighborhood Hits	146
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ANR26_MOUSE
NC score	0.066229 (rank : 519)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	455	Target Neighborhood Hits	1554	Shared Neighborhood Hits	135
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

VCXC_HUMAN
NC score	0.066195 (rank : 520)	θ value	θ > 10 (rank : 1009)
Query Neighborhood Hits	455	Target Neighborhood Hits	139	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

LR37A_HUMAN
NC score	0.066159 (rank : 521)	θ value	θ > 10 (rank : 732)
Query Neighborhood Hits	455	Target Neighborhood Hits	720	Shared Neighborhood Hits	92
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

MYH7_HUMAN
NC score	0.066132 (rank : 522)	θ value	8.99809 (rank : 432)
Query Neighborhood Hits	455	Target Neighborhood Hits	1559	Shared Neighborhood Hits	147
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

MYH1_HUMAN
NC score	0.066130 (rank : 523)	θ value	θ > 10 (rank : 776)
Query Neighborhood Hits	455	Target Neighborhood Hits	1478	Shared Neighborhood Hits	144
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

CARD9_HUMAN
NC score	0.066078 (rank : 524)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	455	Target Neighborhood Hits	602	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

NELFA_HUMAN
NC score	0.066073 (rank : 525)	θ value	8.99809 (rank : 435)
Query Neighborhood Hits	455	Target Neighborhood Hits	161	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H3P2, O95392	Gene names	WHSC2, NELFA
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein).

DMD_MOUSE
NC score	0.066070 (rank : 526)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	455	Target Neighborhood Hits	1111	Shared Neighborhood Hits	117
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

GRIN1_MOUSE
NC score	0.066049 (rank : 527)	θ value	θ > 10 (rank : 670)
Query Neighborhood Hits	455	Target Neighborhood Hits	337	Shared Neighborhood Hits	80
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

MYH2_HUMAN
NC score	0.066001 (rank : 528)	θ value	θ > 10 (rank : 778)
Query Neighborhood Hits	455	Target Neighborhood Hits	1491	Shared Neighborhood Hits	147
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

FMN2_HUMAN
NC score	0.065966 (rank : 529)	θ value	θ > 10 (rank : 641)
Query Neighborhood Hits	455	Target Neighborhood Hits	484	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

HOOK2_HUMAN
NC score	0.065922 (rank : 530)	θ value	θ > 10 (rank : 682)
Query Neighborhood Hits	455	Target Neighborhood Hits	714	Shared Neighborhood Hits	96
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

RL1D1_HUMAN
NC score	0.065882 (rank : 531)	θ value	4.03905 (rank : 318)
Query Neighborhood Hits	455	Target Neighborhood Hits	180	Shared Neighborhood Hits	39
SwissProt Accessions	O76021, Q6PL22, Q8IWS7, Q8WUZ1, Q9HDA9, Q9Y3Z9	Gene names	RSL1D1, CATX11, CSIG, PBK1
Domain Architecture	No domain graphic available
Description	Ribosomal L1 domain-containing protein 1 (Cellular senescence- inhibited gene protein) (Protein PBK1) (CATX-11).

KTN1_HUMAN
NC score	0.065768 (rank : 532)	θ value	θ > 10 (rank : 714)
Query Neighborhood Hits	455	Target Neighborhood Hits	1197	Shared Neighborhood Hits	122
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

TCGAP_MOUSE
NC score	0.065744 (rank : 533)	θ value	θ > 10 (rank : 965)
Query Neighborhood Hits	455	Target Neighborhood Hits	409	Shared Neighborhood Hits	101
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

MYH6_MOUSE
NC score	0.065736 (rank : 534)	θ value	6.88961 (rank : 392)
Query Neighborhood Hits	455	Target Neighborhood Hits	1501	Shared Neighborhood Hits	145
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MAP2_HUMAN
NC score	0.065722 (rank : 535)	θ value	θ > 10 (rank : 749)
Query Neighborhood Hits	455	Target Neighborhood Hits	348	Shared Neighborhood Hits	73
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

SYNE1_HUMAN
NC score	0.065627 (rank : 536)	θ value	θ > 10 (rank : 949)
Query Neighborhood Hits	455	Target Neighborhood Hits	1484	Shared Neighborhood Hits	130
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

GRAP1_HUMAN
NC score	0.065583 (rank : 537)	θ value	θ > 10 (rank : 663)
Query Neighborhood Hits	455	Target Neighborhood Hits	944	Shared Neighborhood Hits	111
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

SWP70_MOUSE
NC score	0.065530 (rank : 538)	θ value	θ > 10 (rank : 947)
Query Neighborhood Hits	455	Target Neighborhood Hits	1097	Shared Neighborhood Hits	124
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

RAI14_MOUSE
NC score	0.065482 (rank : 539)	θ value	θ > 10 (rank : 864)
Query Neighborhood Hits	455	Target Neighborhood Hits	1505	Shared Neighborhood Hits	158
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

LRC45_HUMAN
NC score	0.065455 (rank : 540)	θ value	θ > 10 (rank : 733)
Query Neighborhood Hits	455	Target Neighborhood Hits	933	Shared Neighborhood Hits	110
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

MYH1_MOUSE
NC score	0.065444 (rank : 541)	θ value	θ > 10 (rank : 777)
Query Neighborhood Hits	455	Target Neighborhood Hits	1461	Shared Neighborhood Hits	141
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

BICD1_HUMAN
NC score	0.065432 (rank : 542)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	455	Target Neighborhood Hits	844	Shared Neighborhood Hits	106
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

BAG3_HUMAN
NC score	0.065394 (rank : 543)	θ value	8.99809 (rank : 413)
Query Neighborhood Hits	455	Target Neighborhood Hits	314	Shared Neighborhood Hits	69
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

CCDC6_HUMAN
NC score	0.065294 (rank : 544)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	455	Target Neighborhood Hits	723	Shared Neighborhood Hits	103
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

MLL3_MOUSE
NC score	0.065282 (rank : 545)	θ value	θ > 10 (rank : 762)
Query Neighborhood Hits	455	Target Neighborhood Hits	1399	Shared Neighborhood Hits	145
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

LRC45_MOUSE
NC score	0.065243 (rank : 546)	θ value	θ > 10 (rank : 734)
Query Neighborhood Hits	455	Target Neighborhood Hits	959	Shared Neighborhood Hits	102
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

FYCO1_HUMAN
NC score	0.065221 (rank : 547)	θ value	8.99809 (rank : 425)
Query Neighborhood Hits	455	Target Neighborhood Hits	1149	Shared Neighborhood Hits	122
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

NCOR2_MOUSE
NC score	0.065144 (rank : 548)	θ value	6.88961 (rank : 396)
Query Neighborhood Hits	455	Target Neighborhood Hits	790	Shared Neighborhood Hits	118
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

MTSS1_HUMAN
NC score	0.065142 (rank : 549)	θ value	θ > 10 (rank : 767)
Query Neighborhood Hits	455	Target Neighborhood Hits	504	Shared Neighborhood Hits	99
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

IF3A_MOUSE
NC score	0.065109 (rank : 550)	θ value	θ > 10 (rank : 690)
Query Neighborhood Hits	455	Target Neighborhood Hits	871	Shared Neighborhood Hits	99
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

MYH4_MOUSE
NC score	0.065035 (rank : 551)	θ value	θ > 10 (rank : 781)
Query Neighborhood Hits	455	Target Neighborhood Hits	1476	Shared Neighborhood Hits	146
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

RBCC1_MOUSE
NC score	0.064981 (rank : 552)	θ value	θ > 10 (rank : 869)
Query Neighborhood Hits	455	Target Neighborhood Hits	1048	Shared Neighborhood Hits	116
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

ACINU_MOUSE
NC score	0.064963 (rank : 553)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	455	Target Neighborhood Hits	712	Shared Neighborhood Hits	115
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

TUFT1_MOUSE
NC score	0.064948 (rank : 554)	θ value	θ > 10 (rank : 991)
Query Neighborhood Hits	455	Target Neighborhood Hits	732	Shared Neighborhood Hits	98
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

CCD62_HUMAN
NC score	0.064701 (rank : 555)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	455	Target Neighborhood Hits	631	Shared Neighborhood Hits	94
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

SWP70_HUMAN
NC score	0.064670 (rank : 556)	θ value	θ > 10 (rank : 946)
Query Neighborhood Hits	455	Target Neighborhood Hits	973	Shared Neighborhood Hits	112
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

NPBL_MOUSE
NC score	0.064665 (rank : 557)	θ value	θ > 10 (rank : 815)
Query Neighborhood Hits	455	Target Neighborhood Hits	1041	Shared Neighborhood Hits	128
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

UACA_MOUSE
NC score	0.064654 (rank : 558)	θ value	θ > 10 (rank : 999)
Query Neighborhood Hits	455	Target Neighborhood Hits	1620	Shared Neighborhood Hits	136
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

FA47B_HUMAN
NC score	0.064625 (rank : 559)	θ value	θ > 10 (rank : 638)
Query Neighborhood Hits	455	Target Neighborhood Hits	431	Shared Neighborhood Hits	72
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

HOME2_MOUSE
NC score	0.064617 (rank : 560)	θ value	θ > 10 (rank : 679)
Query Neighborhood Hits	455	Target Neighborhood Hits	882	Shared Neighborhood Hits	108
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

XE7_HUMAN
NC score	0.064559 (rank : 561)	θ value	θ > 10 (rank : 1017)
Query Neighborhood Hits	455	Target Neighborhood Hits	738	Shared Neighborhood Hits	90
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

PEPL_MOUSE
NC score	0.064509 (rank : 562)	θ value	θ > 10 (rank : 831)
Query Neighborhood Hits	455	Target Neighborhood Hits	1105	Shared Neighborhood Hits	125
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

CN145_MOUSE
NC score	0.064466 (rank : 563)	θ value	θ > 10 (rank : 577)
Query Neighborhood Hits	455	Target Neighborhood Hits	916	Shared Neighborhood Hits	97
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

RGNEF_MOUSE
NC score	0.064466 (rank : 564)	θ value	θ > 10 (rank : 879)
Query Neighborhood Hits	455	Target Neighborhood Hits	641	Shared Neighborhood Hits	99
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

RFIP4_HUMAN
NC score	0.064374 (rank : 565)	θ value	θ > 10 (rank : 877)
Query Neighborhood Hits	455	Target Neighborhood Hits	785	Shared Neighborhood Hits	99
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

IF2P_HUMAN
NC score	0.064334 (rank : 566)	θ value	θ > 10 (rank : 686)
Query Neighborhood Hits	455	Target Neighborhood Hits	889	Shared Neighborhood Hits	112
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

NOLC1_HUMAN
NC score	0.064306 (rank : 567)	θ value	θ > 10 (rank : 812)
Query Neighborhood Hits	455	Target Neighborhood Hits	452	Shared Neighborhood Hits	58
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

CEP55_MOUSE
NC score	0.064291 (rank : 568)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	455	Target Neighborhood Hits	693	Shared Neighborhood Hits	95
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

FYCO1_MOUSE
NC score	0.064195 (rank : 569)	θ value	θ > 10 (rank : 643)
Query Neighborhood Hits	455	Target Neighborhood Hits	1059	Shared Neighborhood Hits	114
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

HIP1R_MOUSE
NC score	0.064177 (rank : 570)	θ value	θ > 10 (rank : 676)
Query Neighborhood Hits	455	Target Neighborhood Hits	959	Shared Neighborhood Hits	108
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

MUC1_MOUSE
NC score	0.064171 (rank : 571)	θ value	θ > 10 (rank : 769)
Query Neighborhood Hits	455	Target Neighborhood Hits	388	Shared Neighborhood Hits	49
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

CJ012_HUMAN
NC score	0.064140 (rank : 572)	θ value	θ > 10 (rank : 564)
Query Neighborhood Hits	455	Target Neighborhood Hits	467	Shared Neighborhood Hits	82
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

PININ_HUMAN
NC score	0.064128 (rank : 573)	θ value	θ > 10 (rank : 840)
Query Neighborhood Hits	455	Target Neighborhood Hits	753	Shared Neighborhood Hits	106
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

LRRF1_MOUSE
NC score	0.064094 (rank : 574)	θ value	θ > 10 (rank : 735)
Query Neighborhood Hits	455	Target Neighborhood Hits	440	Shared Neighborhood Hits	76
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

TAF3_HUMAN
NC score	0.064092 (rank : 575)	θ value	θ > 10 (rank : 956)
Query Neighborhood Hits	455	Target Neighborhood Hits	568	Shared Neighborhood Hits	95
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

CCD93_HUMAN
NC score	0.064045 (rank : 576)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	455	Target Neighborhood Hits	600	Shared Neighborhood Hits	85
SwissProt Accessions	Q567U6, Q4LE78, Q53TJ2, Q8TBX5, Q9H6R5, Q9NV15	Gene names	CCDC93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

MYH6_HUMAN
NC score	0.064014 (rank : 577)	θ value	θ > 10 (rank : 782)
Query Neighborhood Hits	455	Target Neighborhood Hits	1426	Shared Neighborhood Hits	140
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MD1L1_HUMAN
NC score	0.063979 (rank : 578)	θ value	θ > 10 (rank : 755)
Query Neighborhood Hits	455	Target Neighborhood Hits	893	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

SFPQ_HUMAN
NC score	0.063951 (rank : 579)	θ value	θ > 10 (rank : 909)
Query Neighborhood Hits	455	Target Neighborhood Hits	986	Shared Neighborhood Hits	126
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

KIF5C_MOUSE
NC score	0.063940 (rank : 580)	θ value	3.0926 (rank : 276)
Query Neighborhood Hits	455	Target Neighborhood Hits	1040	Shared Neighborhood Hits	130
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

MYH4_HUMAN
NC score	0.063920 (rank : 581)	θ value	θ > 10 (rank : 780)
Query Neighborhood Hits	455	Target Neighborhood Hits	1377	Shared Neighborhood Hits	133
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

SELV_HUMAN
NC score	0.063841 (rank : 582)	θ value	θ > 10 (rank : 905)
Query Neighborhood Hits	455	Target Neighborhood Hits	118	Shared Neighborhood Hits	35
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

VCX1_HUMAN
NC score	0.063689 (rank : 583)	θ value	θ > 10 (rank : 1007)
Query Neighborhood Hits	455	Target Neighborhood Hits	129	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

EP15_MOUSE
NC score	0.063684 (rank : 584)	θ value	θ > 10 (rank : 628)
Query Neighborhood Hits	455	Target Neighborhood Hits	820	Shared Neighborhood Hits	93
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

CDR2_MOUSE
NC score	0.063614 (rank : 585)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	455	Target Neighborhood Hits	482	Shared Neighborhood Hits	81
SwissProt Accessions	P97817	Gene names	Cdr2
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related protein 2.

CO039_MOUSE
NC score	0.063575 (rank : 586)	θ value	θ > 10 (rank : 584)
Query Neighborhood Hits	455	Target Neighborhood Hits	445	Shared Neighborhood Hits	83
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

C102B_HUMAN
NC score	0.063540 (rank : 587)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	455	Target Neighborhood Hits	542	Shared Neighborhood Hits	80
SwissProt Accessions	Q68D86, Q7Z467, Q8NDK7, Q9H5C1	Gene names	CCDC102B, C18orf14
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 102B.

SDCG8_MOUSE
NC score	0.063455 (rank : 588)	θ value	θ > 10 (rank : 902)
Query Neighborhood Hits	455	Target Neighborhood Hits	886	Shared Neighborhood Hits	112
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

TPM4_HUMAN
NC score	0.063437 (rank : 589)	θ value	θ > 10 (rank : 981)
Query Neighborhood Hits	455	Target Neighborhood Hits	525	Shared Neighborhood Hits	79
SwissProt Accessions	P67936, P07226, Q15659, Q9BU85, Q9H8Q3	Gene names	TPM4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4) (TM30p1).

BICD1_MOUSE
NC score	0.063434 (rank : 590)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	455	Target Neighborhood Hits	837	Shared Neighborhood Hits	101
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

NAF1_HUMAN
NC score	0.063418 (rank : 591)	θ value	θ > 10 (rank : 792)
Query Neighborhood Hits	455	Target Neighborhood Hits	937	Shared Neighborhood Hits	110
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

MBB1A_HUMAN
NC score	0.063395 (rank : 592)	θ value	θ > 10 (rank : 753)
Query Neighborhood Hits	455	Target Neighborhood Hits	665	Shared Neighborhood Hits	101
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

ANM2_MOUSE
NC score	0.063387 (rank : 593)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	455	Target Neighborhood Hits	175	Shared Neighborhood Hits	65
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

K1543_MOUSE
NC score	0.063298 (rank : 594)	θ value	θ > 10 (rank : 703)
Query Neighborhood Hits	455	Target Neighborhood Hits	497	Shared Neighborhood Hits	89
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

IF3A_HUMAN
NC score	0.063262 (rank : 595)	θ value	θ > 10 (rank : 689)
Query Neighborhood Hits	455	Target Neighborhood Hits	875	Shared Neighborhood Hits	97
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

RBCC1_HUMAN
NC score	0.063190 (rank : 596)	θ value	θ > 10 (rank : 868)
Query Neighborhood Hits	455	Target Neighborhood Hits	1023	Shared Neighborhood Hits	109
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

NOXO1_HUMAN
NC score	0.063108 (rank : 597)	θ value	θ > 10 (rank : 813)
Query Neighborhood Hits	455	Target Neighborhood Hits	100	Shared Neighborhood Hits	44
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

ANR18_HUMAN
NC score	0.063065 (rank : 598)	θ value	0.125558 (rank : 90)
Query Neighborhood Hits	455	Target Neighborhood Hits	1106	Shared Neighborhood Hits	111
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

GON4L_HUMAN
NC score	0.062913 (rank : 599)	θ value	4.03905 (rank : 308)
Query Neighborhood Hits	455	Target Neighborhood Hits	555	Shared Neighborhood Hits	102
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

LIPA2_HUMAN
NC score	0.062897 (rank : 600)	θ value	θ > 10 (rank : 720)
Query Neighborhood Hits	455	Target Neighborhood Hits	1044	Shared Neighborhood Hits	119
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

GCC1_HUMAN
NC score	0.062840 (rank : 601)	θ value	θ > 10 (rank : 646)
Query Neighborhood Hits	455	Target Neighborhood Hits	887	Shared Neighborhood Hits	107
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

YLPM1_HUMAN
NC score	0.062839 (rank : 602)	θ value	θ > 10 (rank : 1018)
Query Neighborhood Hits	455	Target Neighborhood Hits	670	Shared Neighborhood Hits	97
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

CIP4_HUMAN
NC score	0.062618 (rank : 603)	θ value	θ > 10 (rank : 563)
Query Neighborhood Hits	455	Target Neighborhood Hits	374	Shared Neighborhood Hits	85
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

LRRF2_MOUSE
NC score	0.062519 (rank : 604)	θ value	θ > 10 (rank : 737)
Query Neighborhood Hits	455	Target Neighborhood Hits	556	Shared Neighborhood Hits	87
SwissProt Accessions	Q91WK0, Q8BVD1, Q9CU89	Gene names	Lrrfip2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

DIAP1_HUMAN
NC score	0.062430 (rank : 605)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	455	Target Neighborhood Hits	784	Shared Neighborhood Hits	113
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

TTC3_HUMAN
NC score	0.062246 (rank : 606)	θ value	2.36792 (rank : 261)
Query Neighborhood Hits	455	Target Neighborhood Hits	664	Shared Neighborhood Hits	91
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

CCD45_MOUSE
NC score	0.062222 (rank : 607)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	455	Target Neighborhood Hits	663	Shared Neighborhood Hits	96
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

MYH14_HUMAN
NC score	0.062026 (rank : 608)	θ value	θ > 10 (rank : 775)
Query Neighborhood Hits	455	Target Neighborhood Hits	995	Shared Neighborhood Hits	105
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

KNTC2_HUMAN
NC score	0.061913 (rank : 609)	θ value	θ > 10 (rank : 712)
Query Neighborhood Hits	455	Target Neighborhood Hits	673	Shared Neighborhood Hits	89
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

MRCKB_HUMAN
NC score	0.061905 (rank : 610)	θ value	0.0736092 (rank : 79)
Query Neighborhood Hits	455	Target Neighborhood Hits	2239	Shared Neighborhood Hits	178
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

CKAP4_HUMAN
NC score	0.061862 (rank : 611)	θ value	θ > 10 (rank : 572)
Query Neighborhood Hits	455	Target Neighborhood Hits	592	Shared Neighborhood Hits	88
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

PCQAP_HUMAN
NC score	0.061831 (rank : 612)	θ value	θ > 10 (rank : 829)
Query Neighborhood Hits	455	Target Neighborhood Hits	549	Shared Neighborhood Hits	75
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

NAF1_MOUSE
NC score	0.061769 (rank : 613)	θ value	θ > 10 (rank : 793)
Query Neighborhood Hits	455	Target Neighborhood Hits	852	Shared Neighborhood Hits	102
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

CEL_HUMAN
NC score	0.061741 (rank : 614)	θ value	1.38821 (rank : 200)
Query Neighborhood Hits	455	Target Neighborhood Hits	896	Shared Neighborhood Hits	125
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

DIAP1_MOUSE
NC score	0.061708 (rank : 615)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	455	Target Neighborhood Hits	839	Shared Neighborhood Hits	117
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

PHLB1_HUMAN
NC score	0.061669 (rank : 616)	θ value	θ > 10 (rank : 834)
Query Neighborhood Hits	455	Target Neighborhood Hits	1038	Shared Neighborhood Hits	151
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

GGN_HUMAN
NC score	0.061613 (rank : 617)	θ value	θ > 10 (rank : 652)
Query Neighborhood Hits	455	Target Neighborhood Hits	269	Shared Neighborhood Hits	52
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GNAS1_MOUSE
NC score	0.061604 (rank : 618)	θ value	0.365318 (rank : 121)
Query Neighborhood Hits	455	Target Neighborhood Hits	651	Shared Neighborhood Hits	96
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

GP73_MOUSE
NC score	0.061569 (rank : 619)	θ value	θ > 10 (rank : 662)
Query Neighborhood Hits	455	Target Neighborhood Hits	506	Shared Neighborhood Hits	96
SwissProt Accessions	Q91XA2	Gene names	Golph2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

ZN207_HUMAN
NC score	0.061566 (rank : 620)	θ value	θ > 10 (rank : 1021)
Query Neighborhood Hits	455	Target Neighborhood Hits	326	Shared Neighborhood Hits	40
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

KINH_MOUSE
NC score	0.061543 (rank : 621)	θ value	θ > 10 (rank : 710)
Query Neighborhood Hits	455	Target Neighborhood Hits	1082	Shared Neighborhood Hits	123
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

DLG5_HUMAN
NC score	0.061525 (rank : 622)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	455	Target Neighborhood Hits	1088	Shared Neighborhood Hits	143
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

HAP1_HUMAN
NC score	0.061506 (rank : 623)	θ value	8.99809 (rank : 428)
Query Neighborhood Hits	455	Target Neighborhood Hits	606	Shared Neighborhood Hits	92
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

FMNL_MOUSE
NC score	0.061451 (rank : 624)	θ value	4.03905 (rank : 307)
Query Neighborhood Hits	455	Target Neighborhood Hits	428	Shared Neighborhood Hits	86
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

CCD27_HUMAN
NC score	0.061416 (rank : 625)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	455	Target Neighborhood Hits	594	Shared Neighborhood Hits	83
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

MILK1_MOUSE
NC score	0.061411 (rank : 626)	θ value	θ > 10 (rank : 758)
Query Neighborhood Hits	455	Target Neighborhood Hits	788	Shared Neighborhood Hits	119
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

TRAK1_HUMAN
NC score	0.061364 (rank : 627)	θ value	θ > 10 (rank : 985)
Query Neighborhood Hits	455	Target Neighborhood Hits	660	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

BRE1A_HUMAN
NC score	0.061355 (rank : 628)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	455	Target Neighborhood Hits	1071	Shared Neighborhood Hits	112
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

CTGE5_MOUSE
NC score	0.061217 (rank : 629)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	455	Target Neighborhood Hits	928	Shared Neighborhood Hits	116
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

RERE_HUMAN
NC score	0.061188 (rank : 630)	θ value	θ > 10 (rank : 873)
Query Neighborhood Hits	455	Target Neighborhood Hits	779	Shared Neighborhood Hits	103
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

NEMO_MOUSE
NC score	0.060882 (rank : 631)	θ value	θ > 10 (rank : 806)
Query Neighborhood Hits	455	Target Neighborhood Hits	658	Shared Neighborhood Hits	96
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

CO002_HUMAN
NC score	0.060871 (rank : 632)	θ value	θ > 10 (rank : 582)
Query Neighborhood Hits	455	Target Neighborhood Hits	387	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

SFR15_HUMAN
NC score	0.060812 (rank : 633)	θ value	4.03905 (rank : 319)
Query Neighborhood Hits	455	Target Neighborhood Hits	368	Shared Neighborhood Hits	46
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

KINH_HUMAN
NC score	0.060812 (rank : 634)	θ value	θ > 10 (rank : 709)
Query Neighborhood Hits	455	Target Neighborhood Hits	1231	Shared Neighborhood Hits	126
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

SPRR3_MOUSE
NC score	0.060780 (rank : 635)	θ value	θ > 10 (rank : 930)
Query Neighborhood Hits	455	Target Neighborhood Hits	106	Shared Neighborhood Hits	28
SwissProt Accessions	O09116	Gene names	Sprr3
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta).

S23IP_MOUSE
NC score	0.060748 (rank : 636)	θ value	3.0926 (rank : 288)
Query Neighborhood Hits	455	Target Neighborhood Hits	363	Shared Neighborhood Hits	63
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

GOG8A_HUMAN
NC score	0.060683 (rank : 637)	θ value	θ > 10 (rank : 654)
Query Neighborhood Hits	455	Target Neighborhood Hits	635	Shared Neighborhood Hits	97
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

CK024_MOUSE
NC score	0.060595 (rank : 638)	θ value	θ > 10 (rank : 570)
Query Neighborhood Hits	455	Target Neighborhood Hits	307	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

IF35_MOUSE
NC score	0.060572 (rank : 639)	θ value	θ > 10 (rank : 688)
Query Neighborhood Hits	455	Target Neighborhood Hits	210	Shared Neighborhood Hits	41
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

IF4G1_HUMAN
NC score	0.060551 (rank : 640)	θ value	0.813845 (rank : 165)
Query Neighborhood Hits	455	Target Neighborhood Hits	347	Shared Neighborhood Hits	67
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

BI2L1_HUMAN
NC score	0.060469 (rank : 641)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	455	Target Neighborhood Hits	156	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

CR034_HUMAN
NC score	0.060460 (rank : 642)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	455	Target Neighborhood Hits	538	Shared Neighborhood Hits	84
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

CCD91_MOUSE
NC score	0.060402 (rank : 643)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	455	Target Neighborhood Hits	699	Shared Neighborhood Hits	88
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

WBP11_HUMAN
NC score	0.060383 (rank : 644)	θ value	θ > 10 (rank : 1014)
Query Neighborhood Hits	455	Target Neighborhood Hits	354	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

GON4L_MOUSE
NC score	0.060380 (rank : 645)	θ value	5.27518 (rank : 337)
Query Neighborhood Hits	455	Target Neighborhood Hits	455	Shared Neighborhood Hits	85
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

RHG04_HUMAN
NC score	0.060241 (rank : 646)	θ value	θ > 10 (rank : 881)
Query Neighborhood Hits	455	Target Neighborhood Hits	307	Shared Neighborhood Hits	80
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

RFIP4_MOUSE
NC score	0.060225 (rank : 647)	θ value	θ > 10 (rank : 878)
Query Neighborhood Hits	455	Target Neighborhood Hits	708	Shared Neighborhood Hits	92
SwissProt Accessions	Q8BQP8, Q80T87	Gene names	Rab11fip4, Kiaa1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

MACF4_HUMAN
NC score	0.060211 (rank : 648)	θ value	θ > 10 (rank : 742)
Query Neighborhood Hits	455	Target Neighborhood Hits	1321	Shared Neighborhood Hits	135
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

KNTC2_MOUSE
NC score	0.060191 (rank : 649)	θ value	θ > 10 (rank : 713)
Query Neighborhood Hits	455	Target Neighborhood Hits	692	Shared Neighborhood Hits	89
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

MUC5B_HUMAN
NC score	0.060185 (rank : 650)	θ value	θ > 10 (rank : 770)
Query Neighborhood Hits	455	Target Neighborhood Hits	1020	Shared Neighborhood Hits	89
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

JIP2_HUMAN
NC score	0.060184 (rank : 651)	θ value	θ > 10 (rank : 698)
Query Neighborhood Hits	455	Target Neighborhood Hits	288	Shared Neighborhood Hits	61
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

GCC1_MOUSE
NC score	0.060161 (rank : 652)	θ value	θ > 10 (rank : 647)
Query Neighborhood Hits	455	Target Neighborhood Hits	777	Shared Neighborhood Hits	95
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GLU2B_MOUSE
NC score	0.060155 (rank : 653)	θ value	2.36792 (rank : 241)
Query Neighborhood Hits	455	Target Neighborhood Hits	357	Shared Neighborhood Hits	59
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

ZWINT_MOUSE
NC score	0.060139 (rank : 654)	θ value	θ > 10 (rank : 1025)
Query Neighborhood Hits	455	Target Neighborhood Hits	497	Shared Neighborhood Hits	81
SwissProt Accessions	Q9CQU5, Q3UYT8, Q91VI4, Q9D0W9	Gene names	Zwint, D10Ertd749e
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

CSKI1_MOUSE
NC score	0.060137 (rank : 655)	θ value	1.06291 (rank : 180)
Query Neighborhood Hits	455	Target Neighborhood Hits	1031	Shared Neighborhood Hits	130
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

GGN_MOUSE
NC score	0.060026 (rank : 656)	θ value	θ > 10 (rank : 653)
Query Neighborhood Hits	455	Target Neighborhood Hits	311	Shared Neighborhood Hits	52
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

HAPIP_HUMAN
NC score	0.059824 (rank : 657)	θ value	θ > 10 (rank : 672)
Query Neighborhood Hits	455	Target Neighborhood Hits	350	Shared Neighborhood Hits	60
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

EVPL_MOUSE
NC score	0.059765 (rank : 658)	θ value	θ > 10 (rank : 636)
Query Neighborhood Hits	455	Target Neighborhood Hits	952	Shared Neighborhood Hits	114
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

ADDB_MOUSE
NC score	0.059743 (rank : 659)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	455	Target Neighborhood Hits	574	Shared Neighborhood Hits	105
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

ZN291_HUMAN
NC score	0.059734 (rank : 660)	θ value	θ > 10 (rank : 1022)
Query Neighborhood Hits	455	Target Neighborhood Hits	647	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

TRAIP_HUMAN
NC score	0.059656 (rank : 661)	θ value	θ > 10 (rank : 983)
Query Neighborhood Hits	455	Target Neighborhood Hits	780	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

MACOI_MOUSE
NC score	0.059607 (rank : 662)	θ value	θ > 10 (rank : 744)
Query Neighborhood Hits	455	Target Neighborhood Hits	620	Shared Neighborhood Hits	89
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

CNOT3_HUMAN
NC score	0.059455 (rank : 663)	θ value	θ > 10 (rank : 578)
Query Neighborhood Hits	455	Target Neighborhood Hits	425	Shared Neighborhood Hits	74
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

BRE1A_MOUSE
NC score	0.059424 (rank : 664)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	455	Target Neighborhood Hits	1025	Shared Neighborhood Hits	104
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

TRDN_HUMAN
NC score	0.059366 (rank : 665)	θ value	θ > 10 (rank : 986)
Query Neighborhood Hits	455	Target Neighborhood Hits	542	Shared Neighborhood Hits	68
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

PLEC1_HUMAN
NC score	0.059316 (rank : 666)	θ value	θ > 10 (rank : 845)
Query Neighborhood Hits	455	Target Neighborhood Hits	1326	Shared Neighborhood Hits	135
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

PRAX_MOUSE
NC score	0.059244 (rank : 667)	θ value	θ > 10 (rank : 850)
Query Neighborhood Hits	455	Target Neighborhood Hits	199	Shared Neighborhood Hits	43
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

RTP3_MOUSE
NC score	0.059210 (rank : 668)	θ value	θ > 10 (rank : 891)
Query Neighborhood Hits	455	Target Neighborhood Hits	374	Shared Neighborhood Hits	79
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

BRD4_HUMAN
NC score	0.059159 (rank : 669)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	455	Target Neighborhood Hits	851	Shared Neighborhood Hits	123
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CJ068_HUMAN
NC score	0.059138 (rank : 670)	θ value	θ > 10 (rank : 565)
Query Neighborhood Hits	455	Target Neighborhood Hits	316	Shared Neighborhood Hits	58
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

TEX9_MOUSE
NC score	0.059022 (rank : 671)	θ value	θ > 10 (rank : 969)
Query Neighborhood Hits	455	Target Neighborhood Hits	581	Shared Neighborhood Hits	84
SwissProt Accessions	Q9D845, O54764	Gene names	Tex9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1).

HGS_MOUSE
NC score	0.058994 (rank : 672)	θ value	θ > 10 (rank : 674)
Query Neighborhood Hits	455	Target Neighborhood Hits	589	Shared Neighborhood Hits	95
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HIP1R_HUMAN
NC score	0.058895 (rank : 673)	θ value	θ > 10 (rank : 675)
Query Neighborhood Hits	455	Target Neighborhood Hits	809	Shared Neighborhood Hits	98
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

EVPL_HUMAN
NC score	0.058835 (rank : 674)	θ value	θ > 10 (rank : 635)
Query Neighborhood Hits	455	Target Neighborhood Hits	895	Shared Neighborhood Hits	105
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

MIPO1_HUMAN
NC score	0.058757 (rank : 675)	θ value	θ > 10 (rank : 759)
Query Neighborhood Hits	455	Target Neighborhood Hits	486	Shared Neighborhood Hits	84
SwissProt Accessions	Q8TD10, Q7Z3J0, Q8IV14	Gene names	MIPOL1
Domain Architecture	No domain graphic available
Description	Mirror-image polydactyly gene 1 protein.

ROCK1_HUMAN
NC score	0.058631 (rank : 676)	θ value	0.0148317 (rank : 50)
Query Neighborhood Hits	455	Target Neighborhood Hits	2000	Shared Neighborhood Hits	151
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

NEB2_MOUSE
NC score	0.058624 (rank : 677)	θ value	θ > 10 (rank : 802)
Query Neighborhood Hits	455	Target Neighborhood Hits	889	Shared Neighborhood Hits	110
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

CAR11_HUMAN
NC score	0.058619 (rank : 678)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	455	Target Neighborhood Hits	690	Shared Neighborhood Hits	91
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

RPGR1_HUMAN
NC score	0.058566 (rank : 679)	θ value	θ > 10 (rank : 888)
Query Neighborhood Hits	455	Target Neighborhood Hits	578	Shared Neighborhood Hits	84
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

ADDA_MOUSE
NC score	0.058537 (rank : 680)	θ value	0.813845 (rank : 157)
Query Neighborhood Hits	455	Target Neighborhood Hits	198	Shared Neighborhood Hits	57
SwissProt Accessions	Q9QYC0, Q9JLE3	Gene names	Add1
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

NCOR1_MOUSE
NC score	0.058380 (rank : 681)	θ value	0.47712 (rank : 136)
Query Neighborhood Hits	455	Target Neighborhood Hits	521	Shared Neighborhood Hits	79
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

CAF1A_MOUSE
NC score	0.058367 (rank : 682)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	455	Target Neighborhood Hits	736	Shared Neighborhood Hits	91
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

FNBP2_HUMAN
NC score	0.058240 (rank : 683)	θ value	θ > 10 (rank : 642)
Query Neighborhood Hits	455	Target Neighborhood Hits	432	Shared Neighborhood Hits	109
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

CENPJ_HUMAN
NC score	0.058221 (rank : 684)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	455	Target Neighborhood Hits	721	Shared Neighborhood Hits	100
SwissProt Accessions	Q9HC77, Q5T6R5, Q96KS5, Q9C067	Gene names	CENPJ, CPAP, LAP, LIP1
Domain Architecture	No domain graphic available
Description	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1).

NDE1_HUMAN
NC score	0.058143 (rank : 685)	θ value	θ > 10 (rank : 800)
Query Neighborhood Hits	455	Target Neighborhood Hits	823	Shared Neighborhood Hits	105
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

SEPT9_HUMAN
NC score	0.058070 (rank : 686)	θ value	θ > 10 (rank : 906)
Query Neighborhood Hits	455	Target Neighborhood Hits	706	Shared Neighborhood Hits	133
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

CNTRB_HUMAN
NC score	0.057995 (rank : 687)	θ value	θ > 10 (rank : 580)
Query Neighborhood Hits	455	Target Neighborhood Hits	690	Shared Neighborhood Hits	89
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

LMNB1_HUMAN
NC score	0.057987 (rank : 688)	θ value	θ > 10 (rank : 728)
Query Neighborhood Hits	455	Target Neighborhood Hits	714	Shared Neighborhood Hits	102
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

MACOI_HUMAN
NC score	0.057986 (rank : 689)	θ value	θ > 10 (rank : 743)
Query Neighborhood Hits	455	Target Neighborhood Hits	650	Shared Neighborhood Hits	90
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

NFRKB_MOUSE
NC score	0.057943 (rank : 690)	θ value	θ > 10 (rank : 808)
Query Neighborhood Hits	455	Target Neighborhood Hits	393	Shared Neighborhood Hits	68
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

K0494_HUMAN
NC score	0.057910 (rank : 691)	θ value	θ > 10 (rank : 700)
Query Neighborhood Hits	455	Target Neighborhood Hits	230	Shared Neighborhood Hits	44
SwissProt Accessions	O75071	Gene names	KIAA0494
Domain Architecture	No domain graphic available
Description	Uncharacterized calcium-binding protein KIAA0494.

DOCK1_HUMAN
NC score	0.057906 (rank : 692)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	455	Target Neighborhood Hits	191	Shared Neighborhood Hits	64
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

SPN90_MOUSE
NC score	0.057901 (rank : 693)	θ value	θ > 10 (rank : 928)
Query Neighborhood Hits	455	Target Neighborhood Hits	157	Shared Neighborhood Hits	46
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

TXLNB_MOUSE
NC score	0.057897 (rank : 694)	θ value	θ > 10 (rank : 993)
Query Neighborhood Hits	455	Target Neighborhood Hits	640	Shared Neighborhood Hits	94
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

TNR6A_HUMAN
NC score	0.057894 (rank : 695)	θ value	0.125558 (rank : 94)
Query Neighborhood Hits	455	Target Neighborhood Hits	343	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

LUZP1_HUMAN
NC score	0.057866 (rank : 696)	θ value	θ > 10 (rank : 738)
Query Neighborhood Hits	455	Target Neighborhood Hits	739	Shared Neighborhood Hits	89
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

MYO5A_HUMAN
NC score	0.057815 (rank : 697)	θ value	θ > 10 (rank : 788)
Query Neighborhood Hits	455	Target Neighborhood Hits	1092	Shared Neighborhood Hits	126
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

SAS6_HUMAN
NC score	0.057614 (rank : 698)	θ value	θ > 10 (rank : 898)
Query Neighborhood Hits	455	Target Neighborhood Hits	791	Shared Neighborhood Hits	94
SwissProt Accessions	Q6UVJ0, Q8N3K0	Gene names	SASS6, SAS6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog (HsSAS-6).

ZC313_HUMAN
NC score	0.057595 (rank : 699)	θ value	θ > 10 (rank : 1020)
Query Neighborhood Hits	455	Target Neighborhood Hits	772	Shared Neighborhood Hits	95
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

TNIP3_HUMAN
NC score	0.057491 (rank : 700)	θ value	θ > 10 (rank : 974)
Query Neighborhood Hits	455	Target Neighborhood Hits	511	Shared Neighborhood Hits	73
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

TAF3_MOUSE
NC score	0.057478 (rank : 701)	θ value	θ > 10 (rank : 957)
Query Neighborhood Hits	455	Target Neighborhood Hits	463	Shared Neighborhood Hits	77
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

CCHCR_HUMAN
NC score	0.057374 (rank : 702)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	455	Target Neighborhood Hits	717	Shared Neighborhood Hits	89
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

TEX9_HUMAN
NC score	0.057220 (rank : 703)	θ value	θ > 10 (rank : 968)
Query Neighborhood Hits	455	Target Neighborhood Hits	541	Shared Neighborhood Hits	78
SwissProt Accessions	Q8N6V9	Gene names	TEX9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein.

CIC_MOUSE
NC score	0.057207 (rank : 704)	θ value	θ > 10 (rank : 561)
Query Neighborhood Hits	455	Target Neighborhood Hits	742	Shared Neighborhood Hits	103
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CCD42_HUMAN
NC score	0.057192 (rank : 705)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	455	Target Neighborhood Hits	406	Shared Neighborhood Hits	68
SwissProt Accessions	Q96M95, Q8N6Q0	Gene names	CCDC42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

CF152_MOUSE
NC score	0.057178 (rank : 706)	θ value	θ > 10 (rank : 557)
Query Neighborhood Hits	455	Target Neighborhood Hits	597	Shared Neighborhood Hits	86
SwissProt Accessions	Q80ST9, Q9CYM9, Q9D5J9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf152 homolog.

CCD27_MOUSE
NC score	0.057127 (rank : 707)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	455	Target Neighborhood Hits	461	Shared Neighborhood Hits	78
SwissProt Accessions	Q3V036	Gene names	Ccdc27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

AKAP2_MOUSE
NC score	0.057120 (rank : 708)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	455	Target Neighborhood Hits	385	Shared Neighborhood Hits	87
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

DREB_MOUSE
NC score	0.057111 (rank : 709)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	455	Target Neighborhood Hits	446	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

SC24C_HUMAN
NC score	0.057047 (rank : 710)	θ value	θ > 10 (rank : 900)
Query Neighborhood Hits	455	Target Neighborhood Hits	662	Shared Neighborhood Hits	89
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

LIPA3_HUMAN
NC score	0.057013 (rank : 711)	θ value	θ > 10 (rank : 722)
Query Neighborhood Hits	455	Target Neighborhood Hits	828	Shared Neighborhood Hits	106
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

LMNB1_MOUSE
NC score	0.056930 (rank : 712)	θ value	θ > 10 (rank : 729)
Query Neighborhood Hits	455	Target Neighborhood Hits	719	Shared Neighborhood Hits	99
SwissProt Accessions	P14733, Q61791	Gene names	Lmnb1
Domain Architecture
Description	Lamin-B1.

YLPM1_MOUSE
NC score	0.056905 (rank : 713)	θ value	θ > 10 (rank : 1019)
Query Neighborhood Hits	455	Target Neighborhood Hits	505	Shared Neighborhood Hits	73
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

CUTL2_MOUSE
NC score	0.056778 (rank : 714)	θ value	5.27518 (rank : 332)
Query Neighborhood Hits	455	Target Neighborhood Hits	771	Shared Neighborhood Hits	94
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

CEP35_HUMAN
NC score	0.056766 (rank : 715)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	455	Target Neighborhood Hits	811	Shared Neighborhood Hits	120
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

NTBP1_MOUSE
NC score	0.056738 (rank : 716)	θ value	θ > 10 (rank : 817)
Query Neighborhood Hits	455	Target Neighborhood Hits	528	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BRM2, Q8CAA8	Gene names	Scyl1bp1, Ntklbp1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (mNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

CLIC6_HUMAN
NC score	0.056727 (rank : 717)	θ value	θ > 10 (rank : 574)
Query Neighborhood Hits	455	Target Neighborhood Hits	289	Shared Neighborhood Hits	47
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

RTN1_MOUSE
NC score	0.056696 (rank : 718)	θ value	0.813845 (rank : 171)
Query Neighborhood Hits	455	Target Neighborhood Hits	189	Shared Neighborhood Hits	43
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

PHLB2_MOUSE
NC score	0.056664 (rank : 719)	θ value	θ > 10 (rank : 836)
Query Neighborhood Hits	455	Target Neighborhood Hits	1016	Shared Neighborhood Hits	116
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PI5PA_HUMAN
NC score	0.056647 (rank : 720)	θ value	θ > 10 (rank : 838)
Query Neighborhood Hits	455	Target Neighborhood Hits	749	Shared Neighborhood Hits	109
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

MPP9_HUMAN
NC score	0.056612 (rank : 721)	θ value	θ > 10 (rank : 766)
Query Neighborhood Hits	455	Target Neighborhood Hits	529	Shared Neighborhood Hits	73
SwissProt Accessions	Q99550, Q9H976	Gene names	MPHOSPH9, MPP9
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 9.

SDPR_MOUSE
NC score	0.056574 (rank : 722)	θ value	θ > 10 (rank : 903)
Query Neighborhood Hits	455	Target Neighborhood Hits	485	Shared Neighborhood Hits	77
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

ALEX_HUMAN
NC score	0.056545 (rank : 723)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	455	Target Neighborhood Hits	361	Shared Neighborhood Hits	60
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

RPGR1_MOUSE
NC score	0.056531 (rank : 724)	θ value	6.88961 (rank : 405)
Query Neighborhood Hits	455	Target Neighborhood Hits	713	Shared Neighborhood Hits	94
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

SPN90_HUMAN
NC score	0.056472 (rank : 725)	θ value	θ > 10 (rank : 927)
Query Neighborhood Hits	455	Target Neighborhood Hits	157	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

CCD45_HUMAN
NC score	0.056386 (rank : 726)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	455	Target Neighborhood Hits	525	Shared Neighborhood Hits	81
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

SF3A2_MOUSE
NC score	0.056379 (rank : 727)	θ value	θ > 10 (rank : 908)
Query Neighborhood Hits	455	Target Neighborhood Hits	247	Shared Neighborhood Hits	48
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

BPA1_MOUSE
NC score	0.056272 (rank : 728)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	455	Target Neighborhood Hits	1477	Shared Neighborhood Hits	146
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

MYO5A_MOUSE
NC score	0.056216 (rank : 729)	θ value	θ > 10 (rank : 789)
Query Neighborhood Hits	455	Target Neighborhood Hits	1117	Shared Neighborhood Hits	118
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

ES8L2_MOUSE
NC score	0.056174 (rank : 730)	θ value	θ > 10 (rank : 633)
Query Neighborhood Hits	455	Target Neighborhood Hits	169	Shared Neighborhood Hits	59
SwissProt Accessions	Q99K30, Q91VT7	Gene names	Eps8l2, Eps8r2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

HCK_MOUSE
NC score	0.056147 (rank : 731)	θ value	7.1131e-05 (rank : 13)
Query Neighborhood Hits	455	Target Neighborhood Hits	1029	Shared Neighborhood Hits	93
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

TRAIP_MOUSE
NC score	0.056130 (rank : 732)	θ value	θ > 10 (rank : 984)
Query Neighborhood Hits	455	Target Neighborhood Hits	745	Shared Neighborhood Hits	89
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

TXLNG_HUMAN
NC score	0.056125 (rank : 733)	θ value	θ > 10 (rank : 994)
Query Neighborhood Hits	455	Target Neighborhood Hits	568	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NUQ3, Q9P0X1	Gene names	TXLNG, CXorf15, LSR5
Domain Architecture	No domain graphic available
Description	Gamma-taxilin (Lipopolysaccharide-specific response protein 5).

MAVS_HUMAN
NC score	0.056016 (rank : 734)	θ value	θ > 10 (rank : 752)
Query Neighborhood Hits	455	Target Neighborhood Hits	271	Shared Neighborhood Hits	60
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

ATN1_HUMAN
NC score	0.055909 (rank : 735)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	455	Target Neighborhood Hits	676	Shared Neighborhood Hits	79
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

AFF1_HUMAN
NC score	0.055876 (rank : 736)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	455	Target Neighborhood Hits	506	Shared Neighborhood Hits	81
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

TM108_MOUSE
NC score	0.055832 (rank : 737)	θ value	θ > 10 (rank : 971)
Query Neighborhood Hits	455	Target Neighborhood Hits	336	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

LMNB2_HUMAN
NC score	0.055752 (rank : 738)	θ value	θ > 10 (rank : 730)
Query Neighborhood Hits	455	Target Neighborhood Hits	723	Shared Neighborhood Hits	86
SwissProt Accessions	Q03252, O75292, Q14734, Q96DF6	Gene names	LMNB2, LMN2
Domain Architecture
Description	Lamin-B2.

WBP11_MOUSE
NC score	0.055738 (rank : 739)	θ value	θ > 10 (rank : 1015)
Query Neighborhood Hits	455	Target Neighborhood Hits	362	Shared Neighborhood Hits	61
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

DOT1L_HUMAN
NC score	0.055653 (rank : 740)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	455	Target Neighborhood Hits	660	Shared Neighborhood Hits	95
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

CAR10_HUMAN
NC score	0.055653 (rank : 741)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	455	Target Neighborhood Hits	569	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

BPAEA_HUMAN
NC score	0.055625 (rank : 742)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	455	Target Neighborhood Hits	1369	Shared Neighborhood Hits	132
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

PCQAP_MOUSE
NC score	0.055559 (rank : 743)	θ value	θ > 10 (rank : 830)
Query Neighborhood Hits	455	Target Neighborhood Hits	506	Shared Neighborhood Hits	77
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

BAIP2_HUMAN
NC score	0.055518 (rank : 744)	θ value	8.99809 (rank : 414)
Query Neighborhood Hits	455	Target Neighborhood Hits	192	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43	Gene names	BAIAP2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Protein BAP2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor substrate p53/p58) (IRSp53/58) (IRS-58) (Fas ligand-associated factor 3) (FLAF3).

MYO5B_HUMAN
NC score	0.055479 (rank : 745)	θ value	θ > 10 (rank : 790)
Query Neighborhood Hits	455	Target Neighborhood Hits	911	Shared Neighborhood Hits	106
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

ARHG8_MOUSE
NC score	0.055429 (rank : 746)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	455	Target Neighborhood Hits	79	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

KIF5C_HUMAN
NC score	0.055427 (rank : 747)	θ value	θ > 10 (rank : 708)
Query Neighborhood Hits	455	Target Neighborhood Hits	974	Shared Neighborhood Hits	121
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

LIPB1_MOUSE
NC score	0.055417 (rank : 748)	θ value	θ > 10 (rank : 724)
Query Neighborhood Hits	455	Target Neighborhood Hits	727	Shared Neighborhood Hits	98
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

ARHG3_MOUSE
NC score	0.055322 (rank : 749)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	455	Target Neighborhood Hits	85	Shared Neighborhood Hits	16
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

SF3A2_HUMAN
NC score	0.055306 (rank : 750)	θ value	θ > 10 (rank : 907)
Query Neighborhood Hits	455	Target Neighborhood Hits	263	Shared Neighborhood Hits	44
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

CTRO_MOUSE
NC score	0.055227 (rank : 751)	θ value	5.27518 (rank : 331)
Query Neighborhood Hits	455	Target Neighborhood Hits	2344	Shared Neighborhood Hits	176
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

RBM25_HUMAN
NC score	0.055208 (rank : 752)	θ value	θ > 10 (rank : 870)
Query Neighborhood Hits	455	Target Neighborhood Hits	682	Shared Neighborhood Hits	87
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

IF35_HUMAN
NC score	0.055068 (rank : 753)	θ value	θ > 10 (rank : 687)
Query Neighborhood Hits	455	Target Neighborhood Hits	130	Shared Neighborhood Hits	33
SwissProt Accessions	O00303, Q8N978	Gene names	EIF3S5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

CR034_MOUSE
NC score	0.055039 (rank : 754)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	455	Target Neighborhood Hits	643	Shared Neighborhood Hits	80
SwissProt Accessions	Q8CDV0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34 homolog.

ARHG3_HUMAN
NC score	0.054997 (rank : 755)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	455	Target Neighborhood Hits	82	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

3BP5_HUMAN
NC score	0.054948 (rank : 756)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	455	Target Neighborhood Hits	375	Shared Neighborhood Hits	63
SwissProt Accessions	O60239	Gene names	SH3BP5, SAB
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

ROCK1_MOUSE
NC score	0.054931 (rank : 757)	θ value	θ > 10 (rank : 886)
Query Neighborhood Hits	455	Target Neighborhood Hits	2126	Shared Neighborhood Hits	153
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

VGF_HUMAN
NC score	0.054926 (rank : 758)	θ value	5.27518 (rank : 362)
Query Neighborhood Hits	455	Target Neighborhood Hits	167	Shared Neighborhood Hits	35
SwissProt Accessions	O15240	Gene names	VGF
Domain Architecture	No domain graphic available
Description	Neurosecretory protein VGF precursor.

NEB2_HUMAN
NC score	0.054898 (rank : 759)	θ value	θ > 10 (rank : 801)
Query Neighborhood Hits	455	Target Neighborhood Hits	883	Shared Neighborhood Hits	110
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEUM_HUMAN
NC score	0.054833 (rank : 760)	θ value	θ > 10 (rank : 807)
Query Neighborhood Hits	455	Target Neighborhood Hits	132	Shared Neighborhood Hits	35
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

LMNB2_MOUSE
NC score	0.054775 (rank : 761)	θ value	θ > 10 (rank : 731)
Query Neighborhood Hits	455	Target Neighborhood Hits	674	Shared Neighborhood Hits	93
SwissProt Accessions	P21619, P48680, Q8CGB1	Gene names	Lmnb2
Domain Architecture
Description	Lamin-B2.

CKAP4_MOUSE
NC score	0.054750 (rank : 762)	θ value	θ > 10 (rank : 573)
Query Neighborhood Hits	455	Target Neighborhood Hits	596	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

MUCDL_HUMAN
NC score	0.054741 (rank : 763)	θ value	θ > 10 (rank : 771)
Query Neighborhood Hits	455	Target Neighborhood Hits	777	Shared Neighborhood Hits	102
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

CO039_HUMAN
NC score	0.054674 (rank : 764)	θ value	θ > 10 (rank : 583)
Query Neighborhood Hits	455	Target Neighborhood Hits	264	Shared Neighborhood Hits	60
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

CEP55_HUMAN
NC score	0.054604 (rank : 765)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	455	Target Neighborhood Hits	504	Shared Neighborhood Hits	73
SwissProt Accessions	Q53EZ4, Q32WF5, Q3MV20, Q5VY28, Q6N034, Q96H32, Q9NVS7	Gene names	CEP55, C10orf3, URCC6
Domain Architecture	No domain graphic available
Description	Centrosome protein 55 (Up-regulated in colon cancer 6).

ES8L2_HUMAN
NC score	0.054536 (rank : 766)	θ value	θ > 10 (rank : 632)
Query Neighborhood Hits	455	Target Neighborhood Hits	193	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H6S3, Q53GM8, Q8WYW7, Q96K06, Q9H6K9	Gene names	EPS8L2, EPS8R2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

MACF1_HUMAN
NC score	0.054447 (rank : 767)	θ value	θ > 10 (rank : 740)
Query Neighborhood Hits	455	Target Neighborhood Hits	1341	Shared Neighborhood Hits	134
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

ZN318_HUMAN
NC score	0.054443 (rank : 768)	θ value	3.0926 (rank : 293)
Query Neighborhood Hits	455	Target Neighborhood Hits	497	Shared Neighborhood Hits	83
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

ZN318_MOUSE
NC score	0.054191 (rank : 769)	θ value	θ > 10 (rank : 1023)
Query Neighborhood Hits	455	Target Neighborhood Hits	642	Shared Neighborhood Hits	95
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

CAF1A_HUMAN
NC score	0.054165 (rank : 770)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	455	Target Neighborhood Hits	750	Shared Neighborhood Hits	87
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CT151_HUMAN
NC score	0.054148 (rank : 771)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	455	Target Neighborhood Hits	382	Shared Neighborhood Hits	76
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

CN032_MOUSE
NC score	0.054101 (rank : 772)	θ value	θ > 10 (rank : 575)
Query Neighborhood Hits	455	Target Neighborhood Hits	233	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

SNX9_HUMAN
NC score	0.054097 (rank : 773)	θ value	θ > 10 (rank : 925)
Query Neighborhood Hits	455	Target Neighborhood Hits	148	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y5X1, Q9BSI7, Q9BVM1, Q9UJH6, Q9UP20	Gene names	SNX9, SH3PX1
Domain Architecture
Description	Sorting nexin-9 (SH3 and PX domain-containing protein 1) (SDP1 protein).

STIM1_HUMAN
NC score	0.054008 (rank : 774)	θ value	θ > 10 (rank : 944)
Query Neighborhood Hits	455	Target Neighborhood Hits	665	Shared Neighborhood Hits	102
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

PHLB3_HUMAN
NC score	0.053952 (rank : 775)	θ value	θ > 10 (rank : 837)
Query Neighborhood Hits	455	Target Neighborhood Hits	304	Shared Neighborhood Hits	52
SwissProt Accessions	Q6NSJ2, Q8N7Z4	Gene names	PHLDB3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 3.

TXLNG_MOUSE
NC score	0.053941 (rank : 776)	θ value	θ > 10 (rank : 995)
Query Neighborhood Hits	455	Target Neighborhood Hits	552	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BHN1, Q8BP11	Gene names	Txlng
Domain Architecture	No domain graphic available
Description	Gamma-taxilin.

T3JAM_HUMAN
NC score	0.053899 (rank : 777)	θ value	θ > 10 (rank : 951)
Query Neighborhood Hits	455	Target Neighborhood Hits	533	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

CTRO_HUMAN
NC score	0.053891 (rank : 778)	θ value	1.06291 (rank : 182)
Query Neighborhood Hits	455	Target Neighborhood Hits	2092	Shared Neighborhood Hits	165
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

VDP_HUMAN
NC score	0.053854 (rank : 779)	θ value	θ > 10 (rank : 1010)
Query Neighborhood Hits	455	Target Neighborhood Hits	645	Shared Neighborhood Hits	85
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

K1683_HUMAN
NC score	0.053845 (rank : 780)	θ value	θ > 10 (rank : 704)
Query Neighborhood Hits	455	Target Neighborhood Hits	240	Shared Neighborhood Hits	58
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

STIM1_MOUSE
NC score	0.053803 (rank : 781)	θ value	θ > 10 (rank : 945)
Query Neighborhood Hits	455	Target Neighborhood Hits	660	Shared Neighborhood Hits	101
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

GFAP_HUMAN
NC score	0.053763 (rank : 782)	θ value	θ > 10 (rank : 650)
Query Neighborhood Hits	455	Target Neighborhood Hits	723	Shared Neighborhood Hits	95
SwissProt Accessions	P14136, Q53H98, Q5D055, Q6ZQS3, Q7Z5J6, Q7Z5J7, Q96KS4, Q96P18, Q9UFD0	Gene names	GFAP
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

LMBL3_MOUSE
NC score	0.053714 (rank : 783)	θ value	0.0113563 (rank : 44)
Query Neighborhood Hits	455	Target Neighborhood Hits	212	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BLB7, Q641L7, Q6ZPI2, Q8C0G4	Gene names	L3mbtl3
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein).

OXR1_MOUSE
NC score	0.053708 (rank : 784)	θ value	θ > 10 (rank : 827)
Query Neighborhood Hits	455	Target Neighborhood Hits	516	Shared Neighborhood Hits	93
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

CGRE1_HUMAN
NC score	0.053665 (rank : 785)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	455	Target Neighborhood Hits	354	Shared Neighborhood Hits	54
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

INVO_MOUSE
NC score	0.053594 (rank : 786)	θ value	θ > 10 (rank : 696)
Query Neighborhood Hits	455	Target Neighborhood Hits	474	Shared Neighborhood Hits	80
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

RABE2_MOUSE
NC score	0.053558 (rank : 787)	θ value	θ > 10 (rank : 860)
Query Neighborhood Hits	455	Target Neighborhood Hits	598	Shared Neighborhood Hits	86
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

NOL10_HUMAN
NC score	0.053512 (rank : 788)	θ value	2.36792 (rank : 252)
Query Neighborhood Hits	455	Target Neighborhood Hits	254	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BSC4, Q53RC9, Q96TA5, Q9H7Y7, Q9H855	Gene names	NOL10
Domain Architecture	No domain graphic available
Description	Nucleolar protein 10.

CDR2_HUMAN
NC score	0.053439 (rank : 789)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	455	Target Neighborhood Hits	404	Shared Neighborhood Hits	77
SwissProt Accessions	Q01850, Q13977	Gene names	CDR2, PCD17
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related protein 2 (Paraneoplastic cerebellar degeneration-associated antigen) (Major Yo paraneoplastic antigen).

SKIL_MOUSE
NC score	0.053427 (rank : 790)	θ value	θ > 10 (rank : 916)
Query Neighborhood Hits	455	Target Neighborhood Hits	719	Shared Neighborhood Hits	103
SwissProt Accessions	Q60665, Q60702, Q78E90, Q80VK5	Gene names	Skil, Skir, Sno
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

RUFY1_HUMAN
NC score	0.053411 (rank : 791)	θ value	θ > 10 (rank : 892)
Query Neighborhood Hits	455	Target Neighborhood Hits	848	Shared Neighborhood Hits	94
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

T22D2_HUMAN
NC score	0.053408 (rank : 792)	θ value	θ > 10 (rank : 950)
Query Neighborhood Hits	455	Target Neighborhood Hits	250	Shared Neighborhood Hits	44
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

CRCM_HUMAN
NC score	0.053382 (rank : 793)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	455	Target Neighborhood Hits	520	Shared Neighborhood Hits	74
SwissProt Accessions	P23508	Gene names	MCC
Domain Architecture
Description	Colorectal mutant cancer protein (Protein MCC).

TP53B_HUMAN
NC score	0.053365 (rank : 794)	θ value	θ > 10 (rank : 975)
Query Neighborhood Hits	455	Target Neighborhood Hits	413	Shared Neighborhood Hits	73
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

WDR67_HUMAN
NC score	0.053351 (rank : 795)	θ value	θ > 10 (rank : 1016)
Query Neighborhood Hits	455	Target Neighborhood Hits	782	Shared Neighborhood Hits	85
SwissProt Accessions	Q96DN5, Q3MIR6, Q8TBP9	Gene names	WDR67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67.

LMNA_MOUSE
NC score	0.053180 (rank : 796)	θ value	θ > 10 (rank : 727)
Query Neighborhood Hits	455	Target Neighborhood Hits	661	Shared Neighborhood Hits	100
SwissProt Accessions	P48678, P11516, P97859, Q3TIH0, Q3TTS8, Q3UCA0, Q3UCJ8, Q91WF2, Q9DC21	Gene names	Lmna, Lmn1
Domain Architecture
Description	Lamin-A/C.

MMRN1_HUMAN
NC score	0.053112 (rank : 797)	θ value	θ > 10 (rank : 763)
Query Neighborhood Hits	455	Target Neighborhood Hits	636	Shared Neighborhood Hits	83
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

LMNA_HUMAN
NC score	0.053081 (rank : 798)	θ value	θ > 10 (rank : 726)
Query Neighborhood Hits	455	Target Neighborhood Hits	653	Shared Neighborhood Hits	98
SwissProt Accessions	P02545, P02546, Q969I8, Q96JA2	Gene names	LMNA, LMN1
Domain Architecture
Description	Lamin-A/C (70 kDa lamin) (NY-REN-32 antigen).

REPS1_HUMAN
NC score	0.053068 (rank : 799)	θ value	5.27518 (rank : 356)
Query Neighborhood Hits	455	Target Neighborhood Hits	205	Shared Neighborhood Hits	47
SwissProt Accessions	Q96D71, Q8NDR7, Q8WU62, Q9BXY9	Gene names	REPS1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

MNT_HUMAN
NC score	0.053018 (rank : 800)	θ value	θ > 10 (rank : 764)
Query Neighborhood Hits	455	Target Neighborhood Hits	496	Shared Neighborhood Hits	87
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

SYN1_HUMAN
NC score	0.052878 (rank : 801)	θ value	θ > 10 (rank : 948)
Query Neighborhood Hits	455	Target Neighborhood Hits	419	Shared Neighborhood Hits	64
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

SRGP2_MOUSE
NC score	0.052869 (rank : 802)	θ value	θ > 10 (rank : 936)
Query Neighborhood Hits	455	Target Neighborhood Hits	324	Shared Neighborhood Hits	85
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

3BP1_HUMAN
NC score	0.052797 (rank : 803)	θ value	2.36792 (rank : 234)
Query Neighborhood Hits	455	Target Neighborhood Hits	376	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

PHLB2_HUMAN
NC score	0.052783 (rank : 804)	θ value	θ > 10 (rank : 835)
Query Neighborhood Hits	455	Target Neighborhood Hits	964	Shared Neighborhood Hits	111
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

GFAP_MOUSE
NC score	0.052749 (rank : 805)	θ value	θ > 10 (rank : 651)
Query Neighborhood Hits	455	Target Neighborhood Hits	725	Shared Neighborhood Hits	100
SwissProt Accessions	P03995, Q7TQ30, Q925K3	Gene names	Gfap
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

SPAG5_MOUSE
NC score	0.052721 (rank : 806)	θ value	θ > 10 (rank : 926)
Query Neighborhood Hits	455	Target Neighborhood Hits	612	Shared Neighborhood Hits	87
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

CNOT3_MOUSE
NC score	0.052627 (rank : 807)	θ value	θ > 10 (rank : 579)
Query Neighborhood Hits	455	Target Neighborhood Hits	504	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

ANR11_HUMAN
NC score	0.052621 (rank : 808)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	455	Target Neighborhood Hits	1289	Shared Neighborhood Hits	163
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

POF1B_MOUSE
NC score	0.052587 (rank : 809)	θ value	θ > 10 (rank : 847)
Query Neighborhood Hits	455	Target Neighborhood Hits	530	Shared Neighborhood Hits	74
SwissProt Accessions	Q8K4L4, Q8C3A2	Gene names	Pof1b
Domain Architecture	No domain graphic available
Description	Protein POF1B.

SRGP2_HUMAN
NC score	0.052402 (rank : 810)	θ value	θ > 10 (rank : 935)
Query Neighborhood Hits	455	Target Neighborhood Hits	331	Shared Neighborhood Hits	81
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

BAIP2_MOUSE
NC score	0.052392 (rank : 811)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	455	Target Neighborhood Hits	185	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BKX1, Q91V97, Q923V9, Q923W0	Gene names	Baiap2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor tyrosine kinase 53 kDa substrate).

CEP70_MOUSE
NC score	0.052374 (rank : 812)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	455	Target Neighborhood Hits	532	Shared Neighborhood Hits	74
SwissProt Accessions	Q6IQY5, Q9CRL9, Q9CTS4, Q9JIC1	Gene names	Cep70
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein).

KIF5A_MOUSE
NC score	0.052361 (rank : 813)	θ value	1.81305 (rank : 218)
Query Neighborhood Hits	455	Target Neighborhood Hits	859	Shared Neighborhood Hits	106
SwissProt Accessions	P33175, Q5DTP1, Q6PDY7, Q9Z2F9	Gene names	Kif5a, Kiaa4086, Kif5, Nkhc1
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

KIF4A_HUMAN
NC score	0.051941 (rank : 814)	θ value	θ > 10 (rank : 707)
Query Neighborhood Hits	455	Target Neighborhood Hits	1159	Shared Neighborhood Hits	118
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

TROAP_HUMAN
NC score	0.051891 (rank : 815)	θ value	θ > 10 (rank : 988)
Query Neighborhood Hits	455	Target Neighborhood Hits	258	Shared Neighborhood Hits	50
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

RAI14_HUMAN
NC score	0.051867 (rank : 816)	θ value	θ > 10 (rank : 863)
Query Neighborhood Hits	455	Target Neighborhood Hits	1367	Shared Neighborhood Hits	123
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

CSKI1_HUMAN
NC score	0.051811 (rank : 817)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	455	Target Neighborhood Hits	997	Shared Neighborhood Hits	122
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

AMOL2_HUMAN
NC score	0.051774 (rank : 818)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	455	Target Neighborhood Hits	603	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Y2J4, Q53EP1, Q96F99, Q9UKB4	Gene names	AMOTL2, KIAA0989
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP).

LIPB1_HUMAN
NC score	0.051708 (rank : 819)	θ value	θ > 10 (rank : 723)
Query Neighborhood Hits	455	Target Neighborhood Hits	640	Shared Neighborhood Hits	95
SwissProt Accessions	Q86W92, O75336, Q86X70, Q9NY03, Q9ULJ0	Gene names	PPFIBP1, KIAA1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2).

MACF1_MOUSE
NC score	0.051700 (rank : 820)	θ value	θ > 10 (rank : 741)
Query Neighborhood Hits	455	Target Neighborhood Hits	1313	Shared Neighborhood Hits	132
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

MKL1_MOUSE
NC score	0.051691 (rank : 821)	θ value	θ > 10 (rank : 760)
Query Neighborhood Hits	455	Target Neighborhood Hits	667	Shared Neighborhood Hits	103
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

SMOO_HUMAN
NC score	0.051680 (rank : 822)	θ value	6.88961 (rank : 408)
Query Neighborhood Hits	455	Target Neighborhood Hits	391	Shared Neighborhood Hits	69
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

CTGE5_HUMAN
NC score	0.051532 (rank : 823)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	455	Target Neighborhood Hits	800	Shared Neighborhood Hits	100
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

BRD8_MOUSE
NC score	0.051499 (rank : 824)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	455	Target Neighborhood Hits	422	Shared Neighborhood Hits	75
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

AMOL2_MOUSE
NC score	0.051409 (rank : 825)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	455	Target Neighborhood Hits	591	Shared Neighborhood Hits	82
SwissProt Accessions	Q8K371, Q3TPM1, Q7TPE4, Q8BP84, Q8BS08, Q9QUS0	Gene names	Amotl2
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2.

MNT_MOUSE
NC score	0.051398 (rank : 826)	θ value	θ > 10 (rank : 765)
Query Neighborhood Hits	455	Target Neighborhood Hits	432	Shared Neighborhood Hits	75
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

3BP5_MOUSE
NC score	0.051368 (rank : 827)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	455	Target Neighborhood Hits	346	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z131, Q8C903, Q8VCZ0	Gene names	Sh3bp5, Sab
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

ES8L1_HUMAN
NC score	0.051285 (rank : 828)	θ value	θ > 10 (rank : 631)
Query Neighborhood Hits	455	Target Neighborhood Hits	162	Shared Neighborhood Hits	53
SwissProt Accessions	Q8TE68, Q71RE2, Q8NC10, Q96BB7, Q9BSQ2, Q9GZQ2, Q9NXH0	Gene names	EPS8L1, DRC3, EPS8R1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

RUFY2_MOUSE
NC score	0.051251 (rank : 829)	θ value	θ > 10 (rank : 894)
Query Neighborhood Hits	455	Target Neighborhood Hits	820	Shared Neighborhood Hits	91
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

K0310_HUMAN
NC score	0.051228 (rank : 830)	θ value	θ > 10 (rank : 699)
Query Neighborhood Hits	455	Target Neighborhood Hits	420	Shared Neighborhood Hits	75
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

LIPS_HUMAN
NC score	0.051223 (rank : 831)	θ value	θ > 10 (rank : 725)
Query Neighborhood Hits	455	Target Neighborhood Hits	314	Shared Neighborhood Hits	82
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

HGS_HUMAN
NC score	0.051212 (rank : 832)	θ value	θ > 10 (rank : 673)
Query Neighborhood Hits	455	Target Neighborhood Hits	517	Shared Neighborhood Hits	81
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

TCAL5_HUMAN
NC score	0.051205 (rank : 833)	θ value	θ > 10 (rank : 963)
Query Neighborhood Hits	455	Target Neighborhood Hits	806	Shared Neighborhood Hits	89
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

SRGP1_HUMAN
NC score	0.051195 (rank : 834)	θ value	θ > 10 (rank : 934)
Query Neighborhood Hits	455	Target Neighborhood Hits	390	Shared Neighborhood Hits	91
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

UTRO_HUMAN
NC score	0.051161 (rank : 835)	θ value	θ > 10 (rank : 1000)
Query Neighborhood Hits	455	Target Neighborhood Hits	960	Shared Neighborhood Hits	102
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

VIME_MOUSE
NC score	0.051098 (rank : 836)	θ value	θ > 10 (rank : 1011)
Query Neighborhood Hits	455	Target Neighborhood Hits	716	Shared Neighborhood Hits	99
SwissProt Accessions	P20152, O08704, Q8CCH1	Gene names	Vim
Domain Architecture
Description	Vimentin.

ARHGA_MOUSE
NC score	0.051064 (rank : 837)	θ value	4.03905 (rank : 297)
Query Neighborhood Hits	455	Target Neighborhood Hits	125	Shared Neighborhood Hits	28
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

K1543_HUMAN
NC score	0.050967 (rank : 838)	θ value	θ > 10 (rank : 702)
Query Neighborhood Hits	455	Target Neighborhood Hits	435	Shared Neighborhood Hits	83
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

RUFY3_HUMAN
NC score	0.050958 (rank : 839)	θ value	θ > 10 (rank : 895)
Query Neighborhood Hits	455	Target Neighborhood Hits	594	Shared Neighborhood Hits	83
SwissProt Accessions	Q7L099, O94948, Q9UI00	Gene names	RUFY3, KIAA0871
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

ARHG8_HUMAN
NC score	0.050949 (rank : 840)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	455	Target Neighborhood Hits	85	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

DIDO1_HUMAN
NC score	0.050898 (rank : 841)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	455	Target Neighborhood Hits	960	Shared Neighborhood Hits	120
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

RUFY3_MOUSE
NC score	0.050804 (rank : 842)	θ value	θ > 10 (rank : 896)
Query Neighborhood Hits	455	Target Neighborhood Hits	579	Shared Neighborhood Hits	83
SwissProt Accessions	Q9D394, Q3U348, Q3UF96, Q6PE64, Q8VD10	Gene names	Rufy3, D5Bwg0860e, Ripx
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

CABYR_HUMAN
NC score	0.050803 (rank : 843)	θ value	1.81305 (rank : 215)
Query Neighborhood Hits	455	Target Neighborhood Hits	87	Shared Neighborhood Hits	22
SwissProt Accessions	O75952, Q8WXW5, Q9HAY3, Q9HAY4, Q9HAY5, Q9HCY9	Gene names	CABYR, CBP86, FSP2
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86) (Fibrousheathin-2) (FSP-2).

CEP70_HUMAN
NC score	0.050781 (rank : 844)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	455	Target Neighborhood Hits	432	Shared Neighborhood Hits	68
SwissProt Accessions	Q8NHQ1, Q96B31, Q9H2C3, Q9H2Z1, Q9H940	Gene names	CEP70, BITE
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein) (p10-binding protein).

FGR_HUMAN
NC score	0.050756 (rank : 845)	θ value	0.0563607 (rank : 69)
Query Neighborhood Hits	455	Target Neighborhood Hits	1067	Shared Neighborhood Hits	93
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

GTSE1_HUMAN
NC score	0.050747 (rank : 846)	θ value	θ > 10 (rank : 671)
Query Neighborhood Hits	455	Target Neighborhood Hits	193	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

ZN750_MOUSE
NC score	0.050725 (rank : 847)	θ value	θ > 10 (rank : 1024)
Query Neighborhood Hits	455	Target Neighborhood Hits	346	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

CT096_HUMAN
NC score	0.050707 (rank : 848)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	455	Target Neighborhood Hits	438	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NUD7, Q8N840, Q8NAX5	Gene names	C20orf96
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf96.

RABE2_HUMAN
NC score	0.050706 (rank : 849)	θ value	θ > 10 (rank : 859)
Query Neighborhood Hits	455	Target Neighborhood Hits	545	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H5N1	Gene names	RABEP2, RABPT5B
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

SDC1_HUMAN
NC score	0.050612 (rank : 850)	θ value	0.62314 (rank : 152)
Query Neighborhood Hits	455	Target Neighborhood Hits	57	Shared Neighborhood Hits	12
SwissProt Accessions	P18827, Q96HB7	Gene names	SDC1, SDC
Domain Architecture
Description	Syndecan-1 precursor (SYND1) (CD138 antigen).

PRR13_HUMAN
NC score	0.050459 (rank : 851)	θ value	θ > 10 (rank : 855)
Query Neighborhood Hits	455	Target Neighborhood Hits	105	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

KIF5A_HUMAN
NC score	0.050389 (rank : 852)	θ value	5.27518 (rank : 341)
Query Neighborhood Hits	455	Target Neighborhood Hits	843	Shared Neighborhood Hits	105
SwissProt Accessions	Q12840, Q4LE26	Gene names	KIF5A, NKHC1
Domain Architecture
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

ROCK2_MOUSE
NC score	0.050385 (rank : 853)	θ value	θ > 10 (rank : 887)
Query Neighborhood Hits	455	Target Neighborhood Hits	2072	Shared Neighborhood Hits	151
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

PPIP2_MOUSE
NC score	0.050271 (rank : 854)	θ value	θ > 10 (rank : 848)
Query Neighborhood Hits	455	Target Neighborhood Hits	308	Shared Neighborhood Hits	64
SwissProt Accessions	Q99M15, Q9Z189	Gene names	Pstpip2, Mayp
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2 (Macrophage actin-associated tyrosine-phosphorylated protein) (pp37).

MFAP1_MOUSE
NC score	0.050198 (rank : 855)	θ value	θ > 10 (rank : 757)
Query Neighborhood Hits	455	Target Neighborhood Hits	353	Shared Neighborhood Hits	59
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

REN3B_HUMAN
NC score	0.050131 (rank : 856)	θ value	θ > 10 (rank : 872)
Query Neighborhood Hits	455	Target Neighborhood Hits	412	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

CEP57_MOUSE
NC score	0.050104 (rank : 857)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	455	Target Neighborhood Hits	580	Shared Neighborhood Hits	81
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

MYO15_MOUSE
NC score	0.050068 (rank : 858)	θ value	θ > 10 (rank : 785)
Query Neighborhood Hits	455	Target Neighborhood Hits	467	Shared Neighborhood Hits	97
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

HCK_HUMAN
NC score	0.049583 (rank : 859)	θ value	0.0148317 (rank : 48)
Query Neighborhood Hits	455	Target Neighborhood Hits	1035	Shared Neighborhood Hits	93
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

CCD37_MOUSE
NC score	0.049436 (rank : 860)	θ value	6.88961 (rank : 372)
Query Neighborhood Hits	455	Target Neighborhood Hits	199	Shared Neighborhood Hits	41
SwissProt Accessions	Q80VN0, Q6AXD6	Gene names	Ccdc37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 37.

MYST3_HUMAN
NC score	0.048983 (rank : 861)	θ value	2.36792 (rank : 251)
Query Neighborhood Hits	455	Target Neighborhood Hits	772	Shared Neighborhood Hits	108
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

HUWE1_MOUSE
NC score	0.048848 (rank : 862)	θ value	0.0431538 (rank : 64)
Query Neighborhood Hits	455	Target Neighborhood Hits	406	Shared Neighborhood Hits	59
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

TRIO_HUMAN
NC score	0.048675 (rank : 863)	θ value	1.81305 (rank : 232)
Query Neighborhood Hits	455	Target Neighborhood Hits	1580	Shared Neighborhood Hits	135
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

PRP8_MOUSE
NC score	0.048552 (rank : 864)	θ value	1.06291 (rank : 194)
Query Neighborhood Hits	455	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	Q99PV0, Q5ND30, Q5ND31, Q7TQK2, Q8BRZ5, Q8K001	Gene names	Prpf8, Prp8
Domain Architecture	No domain graphic available
Description	Pre-mRNA-processing-splicing factor 8 (Splicing factor Prp8).

PRP8_HUMAN
NC score	0.048546 (rank : 865)	θ value	1.06291 (rank : 193)
Query Neighborhood Hits	455	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	Q6P2Q9, O14547, O75965	Gene names	PRPF8, PRPC8
Domain Architecture	No domain graphic available
Description	Pre-mRNA-processing-splicing factor 8 (Splicing factor Prp8) (PRP8 homolog) (220 kDa U5 snRNP-specific protein) (p220).

MDN1_HUMAN
NC score	0.048502 (rank : 866)	θ value	5.27518 (rank : 345)
Query Neighborhood Hits	455	Target Neighborhood Hits	662	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

K1C17_MOUSE
NC score	0.048440 (rank : 867)	θ value	2.36792 (rank : 247)
Query Neighborhood Hits	455	Target Neighborhood Hits	456	Shared Neighborhood Hits	73
SwissProt Accessions	Q9QWL7, Q61783	Gene names	Krt17, Krt1-17
Domain Architecture
Description	Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17).

RTN1_HUMAN
NC score	0.048124 (rank : 868)	θ value	6.88961 (rank : 406)
Query Neighborhood Hits	455	Target Neighborhood Hits	173	Shared Neighborhood Hits	35
SwissProt Accessions	Q16799, Q16800, Q16801	Gene names	RTN1, NSP
Domain Architecture
Description	Reticulon-1 (Neuroendocrine-specific protein).

FYN_MOUSE
NC score	0.047801 (rank : 869)	θ value	5.27518 (rank : 336)
Query Neighborhood Hits	455	Target Neighborhood Hits	1073	Shared Neighborhood Hits	96
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

MYO15_HUMAN
NC score	0.047772 (rank : 870)	θ value	6.88961 (rank : 393)
Query Neighborhood Hits	455	Target Neighborhood Hits	671	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

CDC5L_MOUSE
NC score	0.047716 (rank : 871)	θ value	3.0926 (rank : 268)
Query Neighborhood Hits	455	Target Neighborhood Hits	205	Shared Neighborhood Hits	38
SwissProt Accessions	Q6A068, Q8K1J9	Gene names	Cdc5l, Kiaa0432
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-related protein (Cdc5-like protein).

FYN_HUMAN
NC score	0.047570 (rank : 872)	θ value	5.27518 (rank : 335)
Query Neighborhood Hits	455	Target Neighborhood Hits	1078	Shared Neighborhood Hits	96
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

K1C12_HUMAN
NC score	0.047558 (rank : 873)	θ value	0.0736092 (rank : 77)
Query Neighborhood Hits	455	Target Neighborhood Hits	372	Shared Neighborhood Hits	60
SwissProt Accessions	Q99456	Gene names	KRT12
Domain Architecture
Description	Keratin, type I cytoskeletal 12 (Cytokeratin-12) (CK-12) (Keratin-12) (K12).

K1C12_MOUSE
NC score	0.047224 (rank : 874)	θ value	0.279714 (rank : 116)
Query Neighborhood Hits	455	Target Neighborhood Hits	409	Shared Neighborhood Hits	68
SwissProt Accessions	Q64291	Gene names	Krt12, Krt1-12, Krt1.12
Domain Architecture
Description	Keratin, type I cytoskeletal 12 (Cytokeratin-12) (CK-12) (Keratin-12) (K12).

YES_HUMAN
NC score	0.047218 (rank : 875)	θ value	1.81305 (rank : 233)
Query Neighborhood Hits	455	Target Neighborhood Hits	1059	Shared Neighborhood Hits	97
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

TITIN_HUMAN
NC score	0.046661 (rank : 876)	θ value	0.0148317 (rank : 52)
Query Neighborhood Hits	455	Target Neighborhood Hits	2923	Shared Neighborhood Hits	204
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

RIN3_MOUSE
NC score	0.046594 (rank : 877)	θ value	5.27518 (rank : 357)
Query Neighborhood Hits	455	Target Neighborhood Hits	239	Shared Neighborhood Hits	45
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

MKL2_HUMAN
NC score	0.045978 (rank : 878)	θ value	0.62314 (rank : 148)
Query Neighborhood Hits	455	Target Neighborhood Hits	274	Shared Neighborhood Hits	60
SwissProt Accessions	Q9ULH7, Q68CT1, Q6UB16, Q86WW2, Q8N226	Gene names	MKL2, KIAA1243, MRTFB
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B) (Megakaryoblastic leukemia 2).

FGR_MOUSE
NC score	0.045820 (rank : 879)	θ value	4.03905 (rank : 306)
Query Neighborhood Hits	455	Target Neighborhood Hits	1069	Shared Neighborhood Hits	96
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

NP1L3_MOUSE
NC score	0.045817 (rank : 880)	θ value	0.47712 (rank : 138)
Query Neighborhood Hits	455	Target Neighborhood Hits	233	Shared Neighborhood Hits	46
SwissProt Accessions	Q794H2, O54802	Gene names	Nap1l3, Mb20
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 3 (Brain-specific protein MB20).

K1C10_HUMAN
NC score	0.045086 (rank : 881)	θ value	6.88961 (rank : 387)
Query Neighborhood Hits	455	Target Neighborhood Hits	526	Shared Neighborhood Hits	80
SwissProt Accessions	P13645, Q14664, Q8N175	Gene names	KRT10
Domain Architecture
Description	Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10).

CABYR_MOUSE
NC score	0.044972 (rank : 882)	θ value	6.88961 (rank : 370)
Query Neighborhood Hits	455	Target Neighborhood Hits	80	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D424, Q91Y41, Q91Y42	Gene names	Cabyr, Cbp86
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86).

CSKI2_HUMAN
NC score	0.044538 (rank : 883)	θ value	1.06291 (rank : 181)
Query Neighborhood Hits	455	Target Neighborhood Hits	747	Shared Neighborhood Hits	81
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CDC5L_HUMAN
NC score	0.044008 (rank : 884)	θ value	4.03905 (rank : 300)
Query Neighborhood Hits	455	Target Neighborhood Hits	197	Shared Neighborhood Hits	34
SwissProt Accessions	Q99459, Q76N46, Q99974	Gene names	CDC5L, KIAA0432, PCDC5RP
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-like protein (Cdc5-like protein) (Pombe cdc5- related protein).

PHC1_MOUSE
NC score	0.043885 (rank : 885)	θ value	1.38821 (rank : 208)
Query Neighborhood Hits	455	Target Neighborhood Hits	205	Shared Neighborhood Hits	34
SwissProt Accessions	Q64028, P70359, Q64307, Q8BZ80	Gene names	Phc1, Edr, Edr1, Rae28
Domain Architecture
Description	Polyhomeotic-like protein 1 (mPH1) (Early development regulatory protein 1) (RAE-28).

SLAP1_MOUSE
NC score	0.043121 (rank : 886)	θ value	6.88961 (rank : 407)
Query Neighborhood Hits	455	Target Neighborhood Hits	117	Shared Neighborhood Hits	16
SwissProt Accessions	Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8	Gene names	Sla, Slap, Slap1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (mSLAP).

LAMA2_HUMAN
NC score	0.042677 (rank : 887)	θ value	0.62314 (rank : 147)
Query Neighborhood Hits	455	Target Neighborhood Hits	1092	Shared Neighborhood Hits	89
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

CSF1_HUMAN
NC score	0.042350 (rank : 888)	θ value	6.88961 (rank : 375)
Query Neighborhood Hits	455	Target Neighborhood Hits	258	Shared Neighborhood Hits	46
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

PTN23_HUMAN
NC score	0.041857 (rank : 889)	θ value	6.88961 (rank : 403)
Query Neighborhood Hits	455	Target Neighborhood Hits	646	Shared Neighborhood Hits	102
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

RAI1_MOUSE
NC score	0.041546 (rank : 890)	θ value	5.27518 (rank : 355)
Query Neighborhood Hits	455	Target Neighborhood Hits	344	Shared Neighborhood Hits	53
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

GP152_HUMAN
NC score	0.041249 (rank : 891)	θ value	1.81305 (rank : 217)
Query Neighborhood Hits	455	Target Neighborhood Hits	636	Shared Neighborhood Hits	73
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

SYTL1_MOUSE
NC score	0.041066 (rank : 892)	θ value	0.813845 (rank : 174)
Query Neighborhood Hits	455	Target Neighborhood Hits	314	Shared Neighborhood Hits	63
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

MAST4_HUMAN
NC score	0.040577 (rank : 893)	θ value	3.0926 (rank : 279)
Query Neighborhood Hits	455	Target Neighborhood Hits	1804	Shared Neighborhood Hits	169
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

IF39_MOUSE
NC score	0.040401 (rank : 894)	θ value	2.36792 (rank : 245)
Query Neighborhood Hits	455	Target Neighborhood Hits	206	Shared Neighborhood Hits	34
SwissProt Accessions	Q8JZQ9, Q922K2	Gene names	Eif3s9
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116).

AFF4_HUMAN
NC score	0.039600 (rank : 895)	θ value	5.27518 (rank : 326)
Query Neighborhood Hits	455	Target Neighborhood Hits	611	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

LRC48_HUMAN
NC score	0.039160 (rank : 896)	θ value	1.38821 (rank : 203)
Query Neighborhood Hits	455	Target Neighborhood Hits	324	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H069, Q86SF9, Q86W73, Q8IWG0	Gene names	LRRC48
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 48.

PHAR2_HUMAN
NC score	0.038549 (rank : 897)	θ value	5.27518 (rank : 350)
Query Neighborhood Hits	455	Target Neighborhood Hits	208	Shared Neighborhood Hits	31
SwissProt Accessions	O75167, Q68DM2	Gene names	PHACTR2, C6orf56, KIAA0680
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 2.

DNL1_HUMAN
NC score	0.038306 (rank : 898)	θ value	4.03905 (rank : 304)
Query Neighborhood Hits	455	Target Neighborhood Hits	216	Shared Neighborhood Hits	45
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

K1C15_HUMAN
NC score	0.038175 (rank : 899)	θ value	5.27518 (rank : 340)
Query Neighborhood Hits	455	Target Neighborhood Hits	367	Shared Neighborhood Hits	61
SwissProt Accessions	P19012, Q53XV8, Q9BUG4	Gene names	KRT15, KRTB
Domain Architecture
Description	Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15).

FA8A1_HUMAN
NC score	0.037092 (rank : 900)	θ value	3.0926 (rank : 272)
Query Neighborhood Hits	455	Target Neighborhood Hits	53	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UBU6	Gene names	FAM8A1, AHCP
Domain Architecture	No domain graphic available
Description	Protein FAM8A1 (Autosomal highly conserved protein).

ABL1_HUMAN
NC score	0.037072 (rank : 901)	θ value	8.99809 (rank : 411)
Query Neighborhood Hits	455	Target Neighborhood Hits	1220	Shared Neighborhood Hits	111
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

EP400_HUMAN
NC score	0.036926 (rank : 902)	θ value	5.27518 (rank : 333)
Query Neighborhood Hits	455	Target Neighborhood Hits	556	Shared Neighborhood Hits	70
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

PDLI7_HUMAN
NC score	0.036739 (rank : 903)	θ value	0.813845 (rank : 169)
Query Neighborhood Hits	455	Target Neighborhood Hits	547	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

MYT1_MOUSE
NC score	0.036623 (rank : 904)	θ value	0.21417 (rank : 107)
Query Neighborhood Hits	455	Target Neighborhood Hits	385	Shared Neighborhood Hits	55
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

MAGD4_HUMAN
NC score	0.035677 (rank : 905)	θ value	1.06291 (rank : 190)
Query Neighborhood Hits	455	Target Neighborhood Hits	338	Shared Neighborhood Hits	70
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

EP400_MOUSE
NC score	0.035606 (rank : 906)	θ value	8.99809 (rank : 423)
Query Neighborhood Hits	455	Target Neighborhood Hits	592	Shared Neighborhood Hits	88
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

LTB1L_HUMAN
NC score	0.035507 (rank : 907)	θ value	0.0961366 (rank : 86)
Query Neighborhood Hits	455	Target Neighborhood Hits	553	Shared Neighborhood Hits	44
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

SH22A_HUMAN
NC score	0.035366 (rank : 908)	θ value	1.38821 (rank : 210)
Query Neighborhood Hits	455	Target Neighborhood Hits	144	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

RHG25_HUMAN
NC score	0.035216 (rank : 909)	θ value	8.99809 (rank : 440)
Query Neighborhood Hits	455	Target Neighborhood Hits	550	Shared Neighborhood Hits	78
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

CASZ1_HUMAN
NC score	0.033973 (rank : 910)	θ value	0.813845 (rank : 161)
Query Neighborhood Hits	455	Target Neighborhood Hits	473	Shared Neighborhood Hits	24
SwissProt Accessions	Q86V15, Q5T9S1, Q8WX49, Q8WX50, Q9BT16, Q9NXC6	Gene names	CASZ1, CST, ZNF693
Domain Architecture	No domain graphic available
Description	Castor homolog 1 zinc finger protein (Castor-related protein) (Zinc finger protein 693).

LTB1S_HUMAN
NC score	0.033806 (rank : 911)	θ value	0.0961366 (rank : 87)
Query Neighborhood Hits	455	Target Neighborhood Hits	502	Shared Neighborhood Hits	33
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

SLK_MOUSE
NC score	0.033755 (rank : 912)	θ value	5.27518 (rank : 360)
Query Neighborhood Hits	455	Target Neighborhood Hits	1798	Shared Neighborhood Hits	141
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

LR37B_HUMAN
NC score	0.033738 (rank : 913)	θ value	2.36792 (rank : 248)
Query Neighborhood Hits	455	Target Neighborhood Hits	392	Shared Neighborhood Hits	41
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

ADDA_HUMAN
NC score	0.032174 (rank : 914)	θ value	4.03905 (rank : 294)
Query Neighborhood Hits	455	Target Neighborhood Hits	108	Shared Neighborhood Hits	27
SwissProt Accessions	P35611, Q13734, Q14729, Q16156, Q9UJB6	Gene names	ADD1, ADDA
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

SC24B_HUMAN
NC score	0.031560 (rank : 915)	θ value	1.81305 (rank : 227)
Query Neighborhood Hits	455	Target Neighborhood Hits	108	Shared Neighborhood Hits	26
SwissProt Accessions	O95487	Gene names	SEC24B
Domain Architecture
Description	Protein transport protein Sec24B (SEC24-related protein B).

TRI44_HUMAN
NC score	0.031059 (rank : 916)	θ value	2.36792 (rank : 260)
Query Neighborhood Hits	455	Target Neighborhood Hits	393	Shared Neighborhood Hits	45
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

NU153_HUMAN
NC score	0.030650 (rank : 917)	θ value	5.27518 (rank : 348)
Query Neighborhood Hits	455	Target Neighborhood Hits	227	Shared Neighborhood Hits	28
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

TAOK2_MOUSE
NC score	0.030437 (rank : 918)	θ value	8.99809 (rank : 449)
Query Neighborhood Hits	455	Target Neighborhood Hits	1373	Shared Neighborhood Hits	112
SwissProt Accessions	Q6ZQ29, Q7TSS8	Gene names	Taok2, Kiaa0881
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2).

LTB1L_MOUSE
NC score	0.030358 (rank : 919)	θ value	0.47712 (rank : 134)
Query Neighborhood Hits	455	Target Neighborhood Hits	514	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

GNAS1_HUMAN
NC score	0.030327 (rank : 920)	θ value	6.88961 (rank : 381)
Query Neighborhood Hits	455	Target Neighborhood Hits	278	Shared Neighborhood Hits	42
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

KI13B_HUMAN
NC score	0.030285 (rank : 921)	θ value	4.03905 (rank : 312)
Query Neighborhood Hits	455	Target Neighborhood Hits	492	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

HCN2_HUMAN
NC score	0.030223 (rank : 922)	θ value	3.0926 (rank : 274)
Query Neighborhood Hits	455	Target Neighborhood Hits	369	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

MYLK_MOUSE
NC score	0.030218 (rank : 923)	θ value	4.03905 (rank : 315)
Query Neighborhood Hits	455	Target Neighborhood Hits	1489	Shared Neighborhood Hits	102
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

ATF5_MOUSE
NC score	0.029820 (rank : 924)	θ value	3.0926 (rank : 265)
Query Neighborhood Hits	455	Target Neighborhood Hits	62	Shared Neighborhood Hits	9
SwissProt Accessions	O70191, Q58E51, Q99NH6	Gene names	Atf5, Atfx, Nap1
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-5 (Activating transcription factor 5-alpha/beta) (Transcription factor ATFx) (Transcription factor-like protein ODA-10) (BZIP protein ATF7) (NRIF3- associated protein) (NAP1).

SHD_MOUSE
NC score	0.029653 (rank : 925)	θ value	1.38821 (rank : 211)
Query Neighborhood Hits	455	Target Neighborhood Hits	137	Shared Neighborhood Hits	19
SwissProt Accessions	O88834, Q3SYI7	Gene names	Shd
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

MEGF9_HUMAN
NC score	0.029520 (rank : 926)	θ value	4.03905 (rank : 314)
Query Neighborhood Hits	455	Target Neighborhood Hits	557	Shared Neighborhood Hits	55
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

LTB1S_MOUSE
NC score	0.029279 (rank : 927)	θ value	0.47712 (rank : 135)
Query Neighborhood Hits	455	Target Neighborhood Hits	479	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

JHD3B_MOUSE
NC score	0.028878 (rank : 928)	θ value	0.365318 (rank : 122)
Query Neighborhood Hits	455	Target Neighborhood Hits	152	Shared Neighborhood Hits	31
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

CCD25_MOUSE
NC score	0.028636 (rank : 929)	θ value	6.88961 (rank : 371)
Query Neighborhood Hits	455	Target Neighborhood Hits	45	Shared Neighborhood Hits	12
SwissProt Accessions	Q78PG9, Q9CSQ8, Q9CUF8	Gene names	Ccdc25
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 25.

LRC48_MOUSE
NC score	0.028409 (rank : 930)	θ value	5.27518 (rank : 342)
Query Neighborhood Hits	455	Target Neighborhood Hits	252	Shared Neighborhood Hits	21
SwissProt Accessions	Q9D5E4	Gene names	Lrrc48
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 48.

SREC2_MOUSE
NC score	0.028377 (rank : 931)	θ value	5.27518 (rank : 361)
Query Neighborhood Hits	455	Target Neighborhood Hits	605	Shared Neighborhood Hits	46
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

FBLI1_HUMAN
NC score	0.028352 (rank : 932)	θ value	1.06291 (rank : 187)
Query Neighborhood Hits	455	Target Neighborhood Hits	200	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WUP2, Q5VVE0, Q5VVE1, Q8IX23, Q96T00, Q9UFD6	Gene names	FBLIM1, FBLP1
Domain Architecture
Description	Filamin-binding LIM protein 1 (Filamin-binding LIM protein 1) (FBLP-1) (Mitogen-inducible 2-interacting protein) (MIG2-interacting protein) (Migfilin).

GASP2_MOUSE
NC score	0.027671 (rank : 933)	θ value	6.88961 (rank : 379)
Query Neighborhood Hits	455	Target Neighborhood Hits	228	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BUY8	Gene names	Gprasp2
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 2 (GASP-2).

MINK1_MOUSE
NC score	0.027000 (rank : 934)	θ value	6.88961 (rank : 390)
Query Neighborhood Hits	455	Target Neighborhood Hits	1451	Shared Neighborhood Hits	114
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

RN168_MOUSE
NC score	0.026650 (rank : 935)	θ value	8.99809 (rank : 441)
Query Neighborhood Hits	455	Target Neighborhood Hits	440	Shared Neighborhood Hits	44
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

ASXL1_MOUSE
NC score	0.026617 (rank : 936)	θ value	6.88961 (rank : 366)
Query Neighborhood Hits	455	Target Neighborhood Hits	182	Shared Neighborhood Hits	34
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

K1949_MOUSE
NC score	0.026611 (rank : 937)	θ value	6.88961 (rank : 386)
Query Neighborhood Hits	455	Target Neighborhood Hits	134	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BQ30, Q3UDS6, Q8CEY9, Q8R3D8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1949 homolog.

CLMN_MOUSE
NC score	0.026449 (rank : 938)	θ value	4.03905 (rank : 301)
Query Neighborhood Hits	455	Target Neighborhood Hits	180	Shared Neighborhood Hits	30
SwissProt Accessions	Q8C5W0, Q91V71, Q91XT7, Q91XT8, Q91XU9	Gene names	Clmn
Domain Architecture
Description	Calmin.

TSYL1_MOUSE
NC score	0.026158 (rank : 939)	θ value	6.88961 (rank : 409)
Query Neighborhood Hits	455	Target Neighborhood Hits	105	Shared Neighborhood Hits	23
SwissProt Accessions	O88852, Q3TKW0	Gene names	Tspyl1, Tspyl
Domain Architecture
Description	Testis-specific Y-encoded-like protein 1 (TSPY-like 1).

LNP_HUMAN
NC score	0.025956 (rank : 940)	θ value	4.03905 (rank : 313)
Query Neighborhood Hits	455	Target Neighborhood Hits	62	Shared Neighborhood Hits	13
SwissProt Accessions	Q9C0E8, Q2M2V8, Q2YD99, Q658W8, Q8N5V9, Q96MS5	Gene names	LNP, KIAA1715
Domain Architecture	No domain graphic available
Description	Protein lunapark.

ATBF1_MOUSE
NC score	0.025755 (rank : 941)	θ value	5.27518 (rank : 327)
Query Neighborhood Hits	455	Target Neighborhood Hits	1841	Shared Neighborhood Hits	127
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

NF2L2_MOUSE
NC score	0.025695 (rank : 942)	θ value	6.88961 (rank : 397)
Query Neighborhood Hits	455	Target Neighborhood Hits	183	Shared Neighborhood Hits	31
SwissProt Accessions	Q60795	Gene names	Nfe2l2, Nrf-2, Nrf2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2).

CD2L1_HUMAN
NC score	0.025487 (rank : 943)	θ value	1.38821 (rank : 199)
Query Neighborhood Hits	455	Target Neighborhood Hits	1467	Shared Neighborhood Hits	105
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

POLI_HUMAN
NC score	0.025359 (rank : 944)	θ value	2.36792 (rank : 253)
Query Neighborhood Hits	455	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UNA4, Q8N590, Q9H0S1, Q9NYH6	Gene names	POLI, RAD30B
Domain Architecture	No domain graphic available
Description	DNA polymerase iota (EC 2.7.7.7) (RAD30 homolog B) (Eta2).

MYLK2_HUMAN
NC score	0.025107 (rank : 945)	θ value	8.99809 (rank : 434)
Query Neighborhood Hits	455	Target Neighborhood Hits	920	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H1R3, Q96I84	Gene names	MYLK2
Domain Architecture
Description	Myosin light chain kinase 2, skeletal/cardiac muscle (EC 2.7.11.18) (MLCK2).

GR65_HUMAN
NC score	0.025006 (rank : 946)	θ value	3.0926 (rank : 273)
Query Neighborhood Hits	455	Target Neighborhood Hits	148	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BQQ3, Q8N272, Q96H42	Gene names	GORASP1, GRASP65
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5).

ABCF1_MOUSE
NC score	0.024603 (rank : 947)	θ value	8.99809 (rank : 410)
Query Neighborhood Hits	455	Target Neighborhood Hits	321	Shared Neighborhood Hits	39
SwissProt Accessions	Q6P542, Q6NV71	Gene names	Abcf1
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1.

MYBPH_HUMAN
NC score	0.024555 (rank : 948)	θ value	1.38821 (rank : 205)
Query Neighborhood Hits	455	Target Neighborhood Hits	256	Shared Neighborhood Hits	17
SwissProt Accessions	Q13203, Q16886, Q86YC5	Gene names	MYBPH
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

HCN4_MOUSE
NC score	0.024423 (rank : 949)	θ value	4.03905 (rank : 309)
Query Neighborhood Hits	455	Target Neighborhood Hits	284	Shared Neighborhood Hits	43
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

PLXB1_HUMAN
NC score	0.024001 (rank : 950)	θ value	3.0926 (rank : 285)
Query Neighborhood Hits	455	Target Neighborhood Hits	360	Shared Neighborhood Hits	58
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

HECD1_HUMAN
NC score	0.023828 (rank : 951)	θ value	4.03905 (rank : 310)
Query Neighborhood Hits	455	Target Neighborhood Hits	371	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

PO6F2_MOUSE
NC score	0.023772 (rank : 952)	θ value	5.27518 (rank : 352)
Query Neighborhood Hits	455	Target Neighborhood Hits	639	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

NCOA2_MOUSE
NC score	0.023684 (rank : 953)	θ value	1.81305 (rank : 221)
Query Neighborhood Hits	455	Target Neighborhood Hits	281	Shared Neighborhood Hits	38
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

FA38A_HUMAN
NC score	0.023682 (rank : 954)	θ value	1.06291 (rank : 186)
Query Neighborhood Hits	455	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q92508	Gene names	FAM38A, KIAA0233
Domain Architecture	No domain graphic available
Description	Protein FAM38A.

CSPG3_HUMAN
NC score	0.023500 (rank : 955)	θ value	3.0926 (rank : 271)
Query Neighborhood Hits	455	Target Neighborhood Hits	676	Shared Neighborhood Hits	56
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

VINC_HUMAN
NC score	0.023414 (rank : 956)	θ value	5.27518 (rank : 363)
Query Neighborhood Hits	455	Target Neighborhood Hits	145	Shared Neighborhood Hits	28
SwissProt Accessions	P18206, Q16450, Q5SWX2, Q7Z3B8, Q8IXU7	Gene names	VCL
Domain Architecture
Description	Vinculin (Metavinculin).

CD2L2_HUMAN
NC score	0.022982 (rank : 957)	θ value	5.27518 (rank : 330)
Query Neighborhood Hits	455	Target Neighborhood Hits	1439	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

CLMN_HUMAN
NC score	0.022516 (rank : 958)	θ value	2.36792 (rank : 239)
Query Neighborhood Hits	455	Target Neighborhood Hits	205	Shared Neighborhood Hits	29
SwissProt Accessions	Q96JQ2, Q9H713, Q9HA23, Q9HA57, Q9UFP4, Q9ULN2	Gene names	CLMN, KIAA1188
Domain Architecture
Description	Calmin.

CBX6_HUMAN
NC score	0.022389 (rank : 959)	θ value	8.99809 (rank : 415)
Query Neighborhood Hits	455	Target Neighborhood Hits	104	Shared Neighborhood Hits	24
SwissProt Accessions	O95503, Q96EM5	Gene names	CBX6
Domain Architecture
Description	Chromobox protein homolog 6.

SDCG1_MOUSE
NC score	0.022087 (rank : 960)	θ value	8.99809 (rank : 443)
Query Neighborhood Hits	455	Target Neighborhood Hits	168	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CCP0, Q66JX6, Q8C9R6, Q8CA65, Q8JZT9, Q8R072, Q9CW30, Q9CYB8, Q9D4A9	Gene names	Sdccag1
Domain Architecture
Description	Serologically defined colon cancer antigen 1.

HDGF_HUMAN
NC score	0.022087 (rank : 961)	θ value	3.0926 (rank : 275)
Query Neighborhood Hits	455	Target Neighborhood Hits	61	Shared Neighborhood Hits	10
SwissProt Accessions	P51858, Q5SZ09	Gene names	HDGF, HMG1L2
Domain Architecture
Description	Hepatoma-derived growth factor (HDGF) (High-mobility group protein 1- like 2) (HMG-1L2).

UFO_HUMAN
NC score	0.021903 (rank : 962)	θ value	3.0926 (rank : 292)
Query Neighborhood Hits	455	Target Neighborhood Hits	981	Shared Neighborhood Hits	41
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

CSPG3_MOUSE
NC score	0.021838 (rank : 963)	θ value	2.36792 (rank : 240)
Query Neighborhood Hits	455	Target Neighborhood Hits	657	Shared Neighborhood Hits	45
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

PI51C_HUMAN
NC score	0.021834 (rank : 964)	θ value	3.0926 (rank : 284)
Query Neighborhood Hits	455	Target Neighborhood Hits	109	Shared Neighborhood Hits	29
SwissProt Accessions	O60331, Q7LE07	Gene names	PIP5K1C, KIAA0589
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I gamma) (PtdIns(4)P- 5-kinase gamma) (PtdInsPKIgamma) (PIP5KIgamma).

UT14A_HUMAN
NC score	0.021539 (rank : 965)	θ value	8.99809 (rank : 452)
Query Neighborhood Hits	455	Target Neighborhood Hits	168	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BVJ6, Q5JYF1	Gene names	UTP14A
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog A (Antigen NY-CO- 16).

JPH4_MOUSE
NC score	0.020000 (rank : 966)	θ value	1.38821 (rank : 202)
Query Neighborhood Hits	455	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	Q80WT0, Q8BMI1	Gene names	Jph4, Jphl1
Domain Architecture	No domain graphic available
Description	Junctophilin-4 (Junctophilin-like 1 protein).

ATBF1_HUMAN
NC score	0.019963 (rank : 967)	θ value	3.0926 (rank : 264)
Query Neighborhood Hits	455	Target Neighborhood Hits	1547	Shared Neighborhood Hits	92
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CNTP1_HUMAN
NC score	0.019821 (rank : 968)	θ value	0.813845 (rank : 163)
Query Neighborhood Hits	455	Target Neighborhood Hits	196	Shared Neighborhood Hits	17
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

RUNX1_HUMAN
NC score	0.019585 (rank : 969)	θ value	5.27518 (rank : 358)
Query Neighborhood Hits	455	Target Neighborhood Hits	94	Shared Neighborhood Hits	11
SwissProt Accessions	Q01196, O60472, O60473, O76047, O76089, Q13081, Q13755, Q13756, Q13757, Q13758, Q13759, Q15341, Q15343, Q16122, Q16284, Q16285, Q16286, Q16346, Q16347, Q92479	Gene names	RUNX1, AML1, CBFA2
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

RYR1_HUMAN
NC score	0.019499 (rank : 970)	θ value	5.27518 (rank : 359)
Query Neighborhood Hits	455	Target Neighborhood Hits	303	Shared Neighborhood Hits	43
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

TCEA2_HUMAN
NC score	0.019338 (rank : 971)	θ value	4.03905 (rank : 321)
Query Neighborhood Hits	455	Target Neighborhood Hits	81	Shared Neighborhood Hits	6
SwissProt Accessions	Q15560, Q8TD37, Q8TD38	Gene names	TCEA2
Domain Architecture
Description	Transcription elongation factor A protein 2 (Transcription elongation factor S-II protein 2) (Testis-specific S-II) (Transcription elongation factor TFIIS.l).

LYPD3_HUMAN
NC score	0.019169 (rank : 972)	θ value	5.27518 (rank : 343)
Query Neighborhood Hits	455	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	O95274, Q9UJ74	Gene names	LYPD3, C4.4A
Domain Architecture	No domain graphic available
Description	Ly6/PLAUR domain-containing protein 3 precursor (GPI-anchored metastasis-associated protein C4.4A homolog) (Matrigel-induced gene C4 protein) (MIG-C4).

CFDP1_HUMAN
NC score	0.019095 (rank : 973)	θ value	8.99809 (rank : 417)
Query Neighborhood Hits	455	Target Neighborhood Hits	80	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UEE9, O00393, O00404, Q9UEF0, Q9UEF1, Q9UEF8	Gene names	CFDP1, BCNT
Domain Architecture	No domain graphic available
Description	Craniofacial development protein 1 (Bucentaur).

PICA_MOUSE
NC score	0.018907 (rank : 974)	θ value	5.27518 (rank : 351)
Query Neighborhood Hits	455	Target Neighborhood Hits	63	Shared Neighborhood Hits	12
SwissProt Accessions	Q7M6Y3, Q3TS04, Q811P1, Q8BUF6, Q8CIH8, Q8R0A9, Q8R3E1, Q8VDN5, Q921L0	Gene names	Picalm, Calm, Fit1
Domain Architecture
Description	Phosphatidylinositol-binding clathrin assembly protein (Clathrin assembly lymphoid myeloid leukemia) (CALM).

BARH2_MOUSE
NC score	0.018767 (rank : 975)	θ value	0.0252991 (rank : 54)
Query Neighborhood Hits	455	Target Neighborhood Hits	397	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VIB5, Q66L43	Gene names	Barhl2, Barh1, Mbh1
Domain Architecture	No domain graphic available
Description	BarH-like 2 homeobox protein (Bar-class homeodomain protein MBH1) (Homeobox protein B-H1).

SN1L2_HUMAN
NC score	0.018737 (rank : 976)	θ value	3.0926 (rank : 289)
Query Neighborhood Hits	455	Target Neighborhood Hits	964	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H0K1, O94878, Q6AZE2, Q76N03, Q8NCV7, Q96CZ8	Gene names	SNF1LK2, KIAA0781, QIK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Qin- induced kinase).

DYSF_MOUSE
NC score	0.018679 (rank : 977)	θ value	4.03905 (rank : 305)
Query Neighborhood Hits	455	Target Neighborhood Hits	162	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

M3K4_MOUSE
NC score	0.017752 (rank : 978)	θ value	5.27518 (rank : 344)
Query Neighborhood Hits	455	Target Neighborhood Hits	924	Shared Neighborhood Hits	44
SwissProt Accessions	O08648, O08649, O70124	Gene names	Map3k4, Mekk4
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4).

CAC1H_HUMAN
NC score	0.017325 (rank : 979)	θ value	5.27518 (rank : 329)
Query Neighborhood Hits	455	Target Neighborhood Hits	307	Shared Neighborhood Hits	35
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

HXA3_MOUSE
NC score	0.017161 (rank : 980)	θ value	6.88961 (rank : 384)
Query Neighborhood Hits	455	Target Neighborhood Hits	558	Shared Neighborhood Hits	61
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

VTNC_MOUSE
NC score	0.017057 (rank : 981)	θ value	8.99809 (rank : 453)
Query Neighborhood Hits	455	Target Neighborhood Hits	74	Shared Neighborhood Hits	8
SwissProt Accessions	P29788, Q8VII4	Gene names	Vtn
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein).

TOIP2_HUMAN
NC score	0.017025 (rank : 982)	θ value	8.99809 (rank : 450)
Query Neighborhood Hits	455	Target Neighborhood Hits	102	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NFQ8	Gene names	TOR1AIP2, LULL1
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2 (Lumenal domain-like LAP1).

PICAL_HUMAN
NC score	0.016860 (rank : 983)	θ value	6.88961 (rank : 400)
Query Neighborhood Hits	455	Target Neighborhood Hits	57	Shared Neighborhood Hits	8
SwissProt Accessions	Q13492, O60700, Q86XZ9	Gene names	PICALM, CALM
Domain Architecture
Description	Phosphatidylinositol-binding clathrin assembly protein (Clathrin assembly lymphoid myeloid leukemia protein).

DAXX_MOUSE
NC score	0.016853 (rank : 984)	θ value	8.99809 (rank : 420)
Query Neighborhood Hits	455	Target Neighborhood Hits	173	Shared Neighborhood Hits	17
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

MYOM1_MOUSE
NC score	0.016758 (rank : 985)	θ value	6.88961 (rank : 394)
Query Neighborhood Hits	455	Target Neighborhood Hits	415	Shared Neighborhood Hits	24
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

DDX21_MOUSE
NC score	0.016582 (rank : 986)	θ value	4.03905 (rank : 303)
Query Neighborhood Hits	455	Target Neighborhood Hits	350	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

RUNX1_MOUSE
NC score	0.016361 (rank : 987)	θ value	8.99809 (rank : 442)
Query Neighborhood Hits	455	Target Neighborhood Hits	93	Shared Neighborhood Hits	14
SwissProt Accessions	Q03347, O08598, Q62049, Q9ESB9, Q9ET65	Gene names	Runx1, Aml1, Cbfa2, Pebp2ab
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

POLK_MOUSE
NC score	0.015992 (rank : 988)	θ value	6.88961 (rank : 401)
Query Neighborhood Hits	455	Target Neighborhood Hits	66	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QUG2, Q7TPY7	Gene names	Polk, Dinb1
Domain Architecture	No domain graphic available
Description	DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP).

WWP2_HUMAN
NC score	0.015917 (rank : 989)	θ value	2.36792 (rank : 263)
Query Neighborhood Hits	455	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

IFIT5_HUMAN
NC score	0.015677 (rank : 990)	θ value	6.88961 (rank : 385)
Query Neighborhood Hits	455	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q13325	Gene names	IFIT5, RI58
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 5 (IFIT-5) (Retinoic acid- and interferon-inducible 58 kDa protein).

MEPD_HUMAN
NC score	0.015511 (rank : 991)	θ value	6.88961 (rank : 389)
Query Neighborhood Hits	455	Target Neighborhood Hits	39	Shared Neighborhood Hits	10
SwissProt Accessions	P52888, Q9UCB3	Gene names	THOP1
Domain Architecture
Description	Thimet oligopeptidase (EC 3.4.24.15) (Endopeptidase 24.15) (MP78).

MNDA_HUMAN
NC score	0.014828 (rank : 992)	θ value	8.99809 (rank : 431)
Query Neighborhood Hits	455	Target Neighborhood Hits	76	Shared Neighborhood Hits	20
SwissProt Accessions	P41218	Gene names	MNDA
Domain Architecture
Description	Myeloid cell nuclear differentiation antigen.

PHF8_HUMAN
NC score	0.014396 (rank : 993)	θ value	3.0926 (rank : 283)
Query Neighborhood Hits	455	Target Neighborhood Hits	105	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UPP1, Q5H9U5, Q5VUJ4, Q7Z6D4, Q9HAH2	Gene names	PHF8, KIAA1111, ZNF422
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

ARI3A_HUMAN
NC score	0.014355 (rank : 994)	θ value	8.99809 (rank : 412)
Query Neighborhood Hits	455	Target Neighborhood Hits	80	Shared Neighborhood Hits	12
SwissProt Accessions	Q99856, Q8IZA7	Gene names	ARID3A, DRIL1, DRX, E2FBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 3A (ARID domain- containing protein 3A) (B-cell regulator of IgH transcription) (Bright) (E2F-binding protein 1).

PTPRG_MOUSE
NC score	0.013919 (rank : 995)	θ value	5.27518 (rank : 354)
Query Neighborhood Hits	455	Target Neighborhood Hits	260	Shared Neighborhood Hits	30
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

ODP2_HUMAN
NC score	0.013355 (rank : 996)	θ value	8.99809 (rank : 438)
Query Neighborhood Hits	455	Target Neighborhood Hits	59	Shared Neighborhood Hits	14
SwissProt Accessions	P10515, Q16783	Gene names	DLAT, DLTA
Domain Architecture
Description	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.12) (Pyruvate dehydrogenase complex E2 subunit) (PDCE2) (E2) (Dihydrolipoamide S- acetyltransferase component of pyruvate dehydrogenase complex) (PDC- E2) (70 kDa mitochondrial autoantigen of primary biliary cirrhosis) (PBC) (M2 antigen complex 70 kDa subunit).

APBA3_MOUSE
NC score	0.013119 (rank : 997)	θ value	4.03905 (rank : 296)
Query Neighborhood Hits	455	Target Neighborhood Hits	174	Shared Neighborhood Hits	11
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

GP1BA_HUMAN
NC score	0.012980 (rank : 998)	θ value	6.88961 (rank : 382)
Query Neighborhood Hits	455	Target Neighborhood Hits	407	Shared Neighborhood Hits	32
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

PTPRG_HUMAN
NC score	0.012700 (rank : 999)	θ value	1.06291 (rank : 195)
Query Neighborhood Hits	455	Target Neighborhood Hits	231	Shared Neighborhood Hits	26
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

ENV2_MOUSE
NC score	0.012693 (rank : 1000)	θ value	8.99809 (rank : 422)
Query Neighborhood Hits	455	Target Neighborhood Hits	39	Shared Neighborhood Hits	11
SwissProt Accessions	P11370, Q61529	Gene names	Fv4, Env
Domain Architecture
Description	Retrovirus-related Env polyprotein from Fv-4 locus.

SYT3_MOUSE
NC score	0.012273 (rank : 1001)	θ value	8.99809 (rank : 448)
Query Neighborhood Hits	455	Target Neighborhood Hits	147	Shared Neighborhood Hits	15
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

BHLH3_MOUSE
NC score	0.012259 (rank : 1002)	θ value	6.88961 (rank : 368)
Query Neighborhood Hits	455	Target Neighborhood Hits	70	Shared Neighborhood Hits	7
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

SGCZ_MOUSE
NC score	0.012163 (rank : 1003)	θ value	4.03905 (rank : 320)
Query Neighborhood Hits	455	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BX51, Q3UVZ2, Q8K1E7	Gene names	Sgcz
Domain Architecture
Description	Zeta-sarcoglycan (Zeta-SG) (ZSG1).

BARH2_HUMAN
NC score	0.011969 (rank : 1004)	θ value	6.88961 (rank : 367)
Query Neighborhood Hits	455	Target Neighborhood Hits	419	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NY43, Q7Z4N7	Gene names	BARHL2
Domain Architecture
Description	BarH-like 2 homeobox protein.

TSPY1_HUMAN
NC score	0.011923 (rank : 1005)	θ value	8.99809 (rank : 451)
Query Neighborhood Hits	455	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q01534, O00216, P09002, Q9UNN7	Gene names	TSPY1, TSPY
Domain Architecture
Description	Testis-specific Y-encoded protein 1.

STAT6_MOUSE
NC score	0.011791 (rank : 1006)	θ value	3.0926 (rank : 290)
Query Neighborhood Hits	455	Target Neighborhood Hits	78	Shared Neighborhood Hits	14
SwissProt Accessions	P52633	Gene names	Stat6
Domain Architecture
Description	Signal transducer and transcription activator 6.

CAC1F_MOUSE
NC score	0.010763 (rank : 1007)	θ value	0.62314 (rank : 144)
Query Neighborhood Hits	455	Target Neighborhood Hits	142	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

FA40B_MOUSE
NC score	0.010469 (rank : 1008)	θ value	5.27518 (rank : 334)
Query Neighborhood Hits	455	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C9H6, Q3TQB7, Q80TI6, Q8C7A2	Gene names	Fam40b, Kiaa1170
Domain Architecture	No domain graphic available
Description	Protein FAM40B.

DJBP_HUMAN
NC score	0.010035 (rank : 1009)	θ value	8.99809 (rank : 421)
Query Neighborhood Hits	455	Target Neighborhood Hits	156	Shared Neighborhood Hits	7
SwissProt Accessions	Q5THR3, Q5U5T6, Q9BY88, Q9H5C4, Q9NSF5	Gene names	DJBP, KIAA1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein (CAP-binding protein complex-interacting protein 1).

NRG2_HUMAN
NC score	0.009993 (rank : 1010)	θ value	8.99809 (rank : 437)
Query Neighborhood Hits	455	Target Neighborhood Hits	419	Shared Neighborhood Hits	21
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

BTBD2_HUMAN
NC score	0.009852 (rank : 1011)	θ value	2.36792 (rank : 237)
Query Neighborhood Hits	455	Target Neighborhood Hits	161	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BX70, O60418, O75248, Q7Z5W0, Q96SX8, Q9NPS1, Q9NX81	Gene names	BTBD2
Domain Architecture
Description	BTB/POZ domain-containing protein 2.

GEMI5_MOUSE
NC score	0.009783 (rank : 1012)	θ value	6.88961 (rank : 380)
Query Neighborhood Hits	455	Target Neighborhood Hits	424	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BX17	Gene names	Gemin5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

SSH1_HUMAN
NC score	0.009755 (rank : 1013)	θ value	8.99809 (rank : 447)
Query Neighborhood Hits	455	Target Neighborhood Hits	164	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WYL5, Q6P6C0, Q8N9A7, Q8WYL3, Q8WYL4, Q9P2P8	Gene names	SSH1, KIAA1298, SSH1L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (hSSH-1L).

MARE1_MOUSE
NC score	0.008510 (rank : 1014)	θ value	6.88961 (rank : 388)
Query Neighborhood Hits	455	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q61166, Q7TN34	Gene names	Mapre1
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein RP/EB family member 1 (APC-binding protein EB1) (End-binding protein 1) (EB1).

SOX12_HUMAN
NC score	0.008508 (rank : 1015)	θ value	8.99809 (rank : 446)
Query Neighborhood Hits	455	Target Neighborhood Hits	111	Shared Neighborhood Hits	10
SwissProt Accessions	O15370, Q9NUD4	Gene names	SOX12, SOX22
Domain Architecture
Description	SOX-12 protein (SOX-22 protein).

FOXC2_HUMAN
NC score	0.006820 (rank : 1016)	θ value	8.99809 (rank : 424)
Query Neighborhood Hits	455	Target Neighborhood Hits	236	Shared Neighborhood Hits	32
SwissProt Accessions	Q99958	Gene names	FOXC2, FKHL14, MFH1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

SUHW4_MOUSE
NC score	0.006681 (rank : 1017)	θ value	0.47712 (rank : 140)
Query Neighborhood Hits	455	Target Neighborhood Hits	737	Shared Neighborhood Hits	25
SwissProt Accessions	Q68FE8, Q3T9B1, Q8BI82	Gene names	Suhw4
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

PTPRS_HUMAN
NC score	0.006493 (rank : 1018)	θ value	6.88961 (rank : 404)
Query Neighborhood Hits	455	Target Neighborhood Hits	472	Shared Neighborhood Hits	19
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

BIRC7_HUMAN
NC score	0.005801 (rank : 1019)	θ value	6.88961 (rank : 369)
Query Neighborhood Hits	455	Target Neighborhood Hits	185	Shared Neighborhood Hits	6
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

SL9A1_MOUSE
NC score	0.005258 (rank : 1020)	θ value	8.99809 (rank : 445)
Query Neighborhood Hits	455	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q61165	Gene names	Slc9a1, Nhe1
Domain Architecture
Description	Sodium/hydrogen exchanger 1 (Na(+)/H(+) exchanger 1) (NHE-1) (Solute carrier family 9 member 1).

DDX50_MOUSE
NC score	0.004488 (rank : 1021)	θ value	6.88961 (rank : 376)
Query Neighborhood Hits	455	Target Neighborhood Hits	137	Shared Neighborhood Hits	8
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

RARG2_HUMAN
NC score	-0.001067 (rank : 1022)	θ value	8.99809 (rank : 439)
Query Neighborhood Hits	455	Target Neighborhood Hits	109	Shared Neighborhood Hits	3
SwissProt Accessions	P22932, Q15281	Gene names	RARG, NR1B3
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor gamma-2 (RAR-gamma-2).

ZN692_MOUSE
NC score	-0.002485 (rank : 1023)	θ value	0.62314 (rank : 156)
Query Neighborhood Hits	455	Target Neighborhood Hits	751	Shared Neighborhood Hits	14
SwissProt Accessions	Q3U381	Gene names	Znf692, Zfp692
Domain Architecture	No domain graphic available
Description	Zinc finger protein 692.

PRD16_HUMAN
NC score	-0.005138 (rank : 1024)	θ value	4.03905 (rank : 316)
Query Neighborhood Hits	455	Target Neighborhood Hits	832	Shared Neighborhood Hits	26
SwissProt Accessions	Q9HAZ2, Q8WYJ9, Q9C0I8	Gene names	PRDM16, KIAA1675, MEL1, PFM13
Domain Architecture
Description	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1).

ZN205_HUMAN
NC score	-0.006940 (rank : 1025)	θ value	8.99809 (rank : 455)
Query Neighborhood Hits	455	Target Neighborhood Hits	743	Shared Neighborhood Hits	16
SwissProt Accessions	O95201	Gene names	ZNF205, ZNF210
Domain Architecture
Description	Zinc finger protein 205 (Zinc finger protein 210).