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Network neighborhood for query Sequence : CSKI1_HUMAN

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CSKI1_HUMAN
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CSKI1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	997	Target Neighborhood Hits	997	Shared Neighborhood Hits	997
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI1_MOUSE
θ value	0 (rank : 2)	NC score	0.976254 (rank : 2)
Query Neighborhood Hits	997	Target Neighborhood Hits	1031	Shared Neighborhood Hits	714
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI2_HUMAN
θ value	0 (rank : 3)	NC score	0.947646 (rank : 3)
Query Neighborhood Hits	997	Target Neighborhood Hits	747	Shared Neighborhood Hits	529
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CSKI2_MOUSE
θ value	0 (rank : 4)	NC score	0.942440 (rank : 4)
Query Neighborhood Hits	997	Target Neighborhood Hits	812	Shared Neighborhood Hits	520
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ANKS1_HUMAN
θ value	2.58187e-47 (rank : 5)	NC score	0.880761 (rank : 5)
Query Neighborhood Hits	997	Target Neighborhood Hits	438	Shared Neighborhood Hits	342
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ANKS1_MOUSE
θ value	8.30557e-46 (rank : 6)	NC score	0.872711 (rank : 6)
Query Neighborhood Hits	997	Target Neighborhood Hits	453	Shared Neighborhood Hits	348
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ANK1_MOUSE
θ value	4.14116e-29 (rank : 7)	NC score	0.840975 (rank : 31)
Query Neighborhood Hits	997	Target Neighborhood Hits	430	Shared Neighborhood Hits	307
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ANK2_HUMAN
θ value	1.2049e-28 (rank : 8)	NC score	0.811154 (rank : 68)
Query Neighborhood Hits	997	Target Neighborhood Hits	1615	Shared Neighborhood Hits	569
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

RIPK4_HUMAN
θ value	2.68423e-28 (rank : 9)	NC score	0.579381 (rank : 201)
Query Neighborhood Hits	997	Target Neighborhood Hits	1094	Shared Neighborhood Hits	359
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

ANK1_HUMAN
θ value	3.50572e-28 (rank : 10)	NC score	0.841609 (rank : 30)
Query Neighborhood Hits	997	Target Neighborhood Hits	416	Shared Neighborhood Hits	304
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANR28_MOUSE
θ value	5.06226e-27 (rank : 11)	NC score	0.848299 (rank : 25)
Query Neighborhood Hits	997	Target Neighborhood Hits	314	Shared Neighborhood Hits	295
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANK3_HUMAN
θ value	6.61148e-27 (rank : 12)	NC score	0.835376 (rank : 37)
Query Neighborhood Hits	997	Target Neighborhood Hits	853	Shared Neighborhood Hits	367
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ANR28_HUMAN
θ value	6.61148e-27 (rank : 13)	NC score	0.847031 (rank : 27)
Query Neighborhood Hits	997	Target Neighborhood Hits	314	Shared Neighborhood Hits	297
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR44_HUMAN
θ value	9.54697e-26 (rank : 14)	NC score	0.848554 (rank : 24)
Query Neighborhood Hits	997	Target Neighborhood Hits	318	Shared Neighborhood Hits	298
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

TNKS2_HUMAN
θ value	1.62847e-25 (rank : 15)	NC score	0.849085 (rank : 23)
Query Neighborhood Hits	997	Target Neighborhood Hits	361	Shared Neighborhood Hits	313
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

ANKK1_HUMAN
θ value	4.73814e-25 (rank : 16)	NC score	0.581495 (rank : 200)
Query Neighborhood Hits	997	Target Neighborhood Hits	1075	Shared Neighborhood Hits	352
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

ANKK1_MOUSE
θ value	6.18819e-25 (rank : 17)	NC score	0.568004 (rank : 205)
Query Neighborhood Hits	997	Target Neighborhood Hits	1072	Shared Neighborhood Hits	350
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

INVS_HUMAN
θ value	1.80048e-24 (rank : 18)	NC score	0.850967 (rank : 17)
Query Neighborhood Hits	997	Target Neighborhood Hits	455	Shared Neighborhood Hits	337
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

ANR50_HUMAN
θ value	2.35151e-24 (rank : 19)	NC score	0.860492 (rank : 12)
Query Neighborhood Hits	997	Target Neighborhood Hits	361	Shared Neighborhood Hits	301
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

TNKS1_HUMAN
θ value	5.23862e-24 (rank : 20)	NC score	0.859324 (rank : 13)
Query Neighborhood Hits	997	Target Neighborhood Hits	477	Shared Neighborhood Hits	377
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

INVS_MOUSE
θ value	6.84181e-24 (rank : 21)	NC score	0.847411 (rank : 26)
Query Neighborhood Hits	997	Target Neighborhood Hits	609	Shared Neighborhood Hits	384
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

DAPK1_MOUSE
θ value	1.16704e-23 (rank : 22)	NC score	0.416437 (rank : 253)
Query Neighborhood Hits	997	Target Neighborhood Hits	1138	Shared Neighborhood Hits	356
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

DAPK1_HUMAN
θ value	1.99067e-23 (rank : 23)	NC score	0.408220 (rank : 261)
Query Neighborhood Hits	997	Target Neighborhood Hits	1130	Shared Neighborhood Hits	351
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

MYPT1_MOUSE
θ value	4.43474e-23 (rank : 24)	NC score	0.826256 (rank : 49)
Query Neighborhood Hits	997	Target Neighborhood Hits	539	Shared Neighborhood Hits	305
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

ANR52_HUMAN
θ value	5.79196e-23 (rank : 25)	NC score	0.840188 (rank : 33)
Query Neighborhood Hits	997	Target Neighborhood Hits	322	Shared Neighborhood Hits	297
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

MYPT1_HUMAN
θ value	5.79196e-23 (rank : 26)	NC score	0.805953 (rank : 79)
Query Neighborhood Hits	997	Target Neighborhood Hits	723	Shared Neighborhood Hits	307
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

TNI3K_HUMAN
θ value	5.79196e-23 (rank : 27)	NC score	0.470942 (rank : 237)
Query Neighborhood Hits	997	Target Neighborhood Hits	1084	Shared Neighborhood Hits	350
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

ANR52_MOUSE
θ value	7.56453e-23 (rank : 28)	NC score	0.840513 (rank : 32)
Query Neighborhood Hits	997	Target Neighborhood Hits	318	Shared Neighborhood Hits	297
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

MIB1_HUMAN
θ value	1.6852e-22 (rank : 29)	NC score	0.817423 (rank : 60)
Query Neighborhood Hits	997	Target Neighborhood Hits	470	Shared Neighborhood Hits	300
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	1.6852e-22 (rank : 30)	NC score	0.817045 (rank : 61)
Query Neighborhood Hits	997	Target Neighborhood Hits	471	Shared Neighborhood Hits	299
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

ANKR6_HUMAN
θ value	3.75424e-22 (rank : 31)	NC score	0.864860 (rank : 10)
Query Neighborhood Hits	997	Target Neighborhood Hits	439	Shared Neighborhood Hits	311
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ASB10_HUMAN
θ value	4.9032e-22 (rank : 32)	NC score	0.850756 (rank : 20)
Query Neighborhood Hits	997	Target Neighborhood Hits	291	Shared Neighborhood Hits	280
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ANR42_HUMAN
θ value	1.09232e-21 (rank : 33)	NC score	0.854300 (rank : 16)
Query Neighborhood Hits	997	Target Neighborhood Hits	284	Shared Neighborhood Hits	275
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ASB3_MOUSE
θ value	1.42661e-21 (rank : 34)	NC score	0.850696 (rank : 21)
Query Neighborhood Hits	997	Target Neighborhood Hits	316	Shared Neighborhood Hits	290
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

TNI3K_MOUSE
θ value	2.43343e-21 (rank : 35)	NC score	0.465058 (rank : 241)
Query Neighborhood Hits	997	Target Neighborhood Hits	1079	Shared Neighborhood Hits	350
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

ASB10_MOUSE
θ value	5.42112e-21 (rank : 36)	NC score	0.850884 (rank : 18)
Query Neighborhood Hits	997	Target Neighborhood Hits	301	Shared Neighborhood Hits	285
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ZDH17_HUMAN
θ value	7.0802e-21 (rank : 37)	NC score	0.752098 (rank : 132)
Query Neighborhood Hits	997	Target Neighborhood Hits	334	Shared Neighborhood Hits	283
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

ASB3_HUMAN
θ value	9.24701e-21 (rank : 38)	NC score	0.850576 (rank : 22)
Query Neighborhood Hits	997	Target Neighborhood Hits	316	Shared Neighborhood Hits	293
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

RAI14_HUMAN
θ value	1.2077e-20 (rank : 39)	NC score	0.630255 (rank : 191)
Query Neighborhood Hits	997	Target Neighborhood Hits	1367	Shared Neighborhood Hits	355
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

RAI14_MOUSE
θ value	1.2077e-20 (rank : 40)	NC score	0.598953 (rank : 194)
Query Neighborhood Hits	997	Target Neighborhood Hits	1505	Shared Neighborhood Hits	362
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

ZDH17_MOUSE
θ value	1.2077e-20 (rank : 41)	NC score	0.747682 (rank : 138)
Query Neighborhood Hits	997	Target Neighborhood Hits	328	Shared Neighborhood Hits	277
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

ANR42_MOUSE
θ value	2.69047e-20 (rank : 42)	NC score	0.850785 (rank : 19)
Query Neighborhood Hits	997	Target Neighborhood Hits	334	Shared Neighborhood Hits	281
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

MUC1_HUMAN
θ value	4.58923e-20 (rank : 43)	NC score	0.167638 (rank : 305)
Query Neighborhood Hits	997	Target Neighborhood Hits	975	Shared Neighborhood Hits	316
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

ASB7_MOUSE
θ value	5.99374e-20 (rank : 44)	NC score	0.854979 (rank : 14)
Query Neighborhood Hits	997	Target Neighborhood Hits	296	Shared Neighborhood Hits	283
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ANR29_HUMAN
θ value	7.82807e-20 (rank : 45)	NC score	0.868863 (rank : 7)
Query Neighborhood Hits	997	Target Neighborhood Hits	294	Shared Neighborhood Hits	284
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

ASB7_HUMAN
θ value	7.82807e-20 (rank : 46)	NC score	0.854966 (rank : 15)
Query Neighborhood Hits	997	Target Neighborhood Hits	296	Shared Neighborhood Hits	283
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

PA2G6_MOUSE
θ value	2.27762e-19 (rank : 47)	NC score	0.826291 (rank : 48)
Query Neighborhood Hits	997	Target Neighborhood Hits	293	Shared Neighborhood Hits	279
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

MYPT2_HUMAN
θ value	2.97466e-19 (rank : 48)	NC score	0.808976 (rank : 71)
Query Neighborhood Hits	997	Target Neighborhood Hits	707	Shared Neighborhood Hits	310
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

TRPA1_HUMAN
θ value	2.97466e-19 (rank : 49)	NC score	0.826052 (rank : 51)
Query Neighborhood Hits	997	Target Neighborhood Hits	339	Shared Neighborhood Hits	291
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

PSD10_HUMAN
θ value	5.07402e-19 (rank : 50)	NC score	0.868499 (rank : 8)
Query Neighborhood Hits	997	Target Neighborhood Hits	301	Shared Neighborhood Hits	290
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

MIB2_MOUSE
θ value	1.13037e-18 (rank : 51)	NC score	0.805277 (rank : 80)
Query Neighborhood Hits	997	Target Neighborhood Hits	409	Shared Neighborhood Hits	286
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

PSD10_MOUSE
θ value	1.47631e-18 (rank : 52)	NC score	0.866760 (rank : 9)
Query Neighborhood Hits	997	Target Neighborhood Hits	293	Shared Neighborhood Hits	286
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

TRPA1_MOUSE
θ value	3.28887e-18 (rank : 53)	NC score	0.825918 (rank : 52)
Query Neighborhood Hits	997	Target Neighborhood Hits	343	Shared Neighborhood Hits	290
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

EHMT1_HUMAN
θ value	5.60996e-18 (rank : 54)	NC score	0.790193 (rank : 102)
Query Neighborhood Hits	997	Target Neighborhood Hits	417	Shared Neighborhood Hits	315
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

ANR16_HUMAN
θ value	7.32683e-18 (rank : 55)	NC score	0.861089 (rank : 11)
Query Neighborhood Hits	997	Target Neighborhood Hits	286	Shared Neighborhood Hits	280
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

CTTB2_HUMAN
θ value	1.63225e-17 (rank : 56)	NC score	0.733748 (rank : 147)
Query Neighborhood Hits	997	Target Neighborhood Hits	1061	Shared Neighborhood Hits	367
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

MIB2_HUMAN
θ value	1.63225e-17 (rank : 57)	NC score	0.806601 (rank : 77)
Query Neighborhood Hits	997	Target Neighborhood Hits	438	Shared Neighborhood Hits	292
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

ASB15_MOUSE
θ value	2.13179e-17 (rank : 58)	NC score	0.800592 (rank : 86)
Query Neighborhood Hits	997	Target Neighborhood Hits	292	Shared Neighborhood Hits	271
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

NOTC4_HUMAN
θ value	4.74913e-17 (rank : 59)	NC score	0.452894 (rank : 246)
Query Neighborhood Hits	997	Target Neighborhood Hits	905	Shared Neighborhood Hits	328
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

ASB13_HUMAN
θ value	6.20254e-17 (rank : 60)	NC score	0.832514 (rank : 40)
Query Neighborhood Hits	997	Target Neighborhood Hits	293	Shared Neighborhood Hits	284
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB13_MOUSE
θ value	8.10077e-17 (rank : 61)	NC score	0.833022 (rank : 38)
Query Neighborhood Hits	997	Target Neighborhood Hits	293	Shared Neighborhood Hits	284
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

PP16B_MOUSE
θ value	1.38178e-16 (rank : 62)	NC score	0.807637 (rank : 74)
Query Neighborhood Hits	997	Target Neighborhood Hits	302	Shared Neighborhood Hits	279
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

FANK1_HUMAN
θ value	3.07829e-16 (rank : 63)	NC score	0.846407 (rank : 28)
Query Neighborhood Hits	997	Target Neighborhood Hits	326	Shared Neighborhood Hits	291
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

ANKS6_HUMAN
θ value	5.25075e-16 (rank : 64)	NC score	0.826742 (rank : 46)
Query Neighborhood Hits	997	Target Neighborhood Hits	411	Shared Neighborhood Hits	331
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ANKS6_MOUSE
θ value	5.25075e-16 (rank : 65)	NC score	0.826338 (rank : 47)
Query Neighborhood Hits	997	Target Neighborhood Hits	435	Shared Neighborhood Hits	341
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ASB2_MOUSE
θ value	5.25075e-16 (rank : 66)	NC score	0.826093 (rank : 50)
Query Neighborhood Hits	997	Target Neighborhood Hits	321	Shared Neighborhood Hits	284
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

OSBL1_HUMAN
θ value	5.25075e-16 (rank : 67)	NC score	0.661490 (rank : 177)
Query Neighborhood Hits	997	Target Neighborhood Hits	368	Shared Neighborhood Hits	280
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSBL1_MOUSE
θ value	5.25075e-16 (rank : 68)	NC score	0.649311 (rank : 181)
Query Neighborhood Hits	997	Target Neighborhood Hits	336	Shared Neighborhood Hits	280
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

PP16B_HUMAN
θ value	5.25075e-16 (rank : 69)	NC score	0.809416 (rank : 69)
Query Neighborhood Hits	997	Target Neighborhood Hits	307	Shared Neighborhood Hits	281
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

NOTC4_MOUSE
θ value	6.85773e-16 (rank : 70)	NC score	0.456936 (rank : 245)
Query Neighborhood Hits	997	Target Neighborhood Hits	872	Shared Neighborhood Hits	313
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

ZDH13_MOUSE
θ value	1.52774e-15 (rank : 71)	NC score	0.737813 (rank : 145)
Query Neighborhood Hits	997	Target Neighborhood Hits	329	Shared Neighborhood Hits	283
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

EHMT2_MOUSE
θ value	1.99529e-15 (rank : 72)	NC score	0.775951 (rank : 118)
Query Neighborhood Hits	997	Target Neighborhood Hits	750	Shared Neighborhood Hits	416
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

FANK1_MOUSE
θ value	1.99529e-15 (rank : 73)	NC score	0.845061 (rank : 29)
Query Neighborhood Hits	997	Target Neighborhood Hits	325	Shared Neighborhood Hits	292
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

ANR35_HUMAN
θ value	2.60593e-15 (rank : 74)	NC score	0.772556 (rank : 122)
Query Neighborhood Hits	997	Target Neighborhood Hits	784	Shared Neighborhood Hits	310
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

EHMT2_HUMAN
θ value	3.40345e-15 (rank : 75)	NC score	0.778769 (rank : 114)
Query Neighborhood Hits	997	Target Neighborhood Hits	498	Shared Neighborhood Hits	321
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ANR21_HUMAN
θ value	5.8054e-15 (rank : 76)	NC score	0.714299 (rank : 154)
Query Neighborhood Hits	997	Target Neighborhood Hits	864	Shared Neighborhood Hits	306
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

ASB5_MOUSE
θ value	9.90251e-15 (rank : 77)	NC score	0.795641 (rank : 93)
Query Neighborhood Hits	997	Target Neighborhood Hits	266	Shared Neighborhood Hits	257
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

BCL3_HUMAN
θ value	1.29331e-14 (rank : 78)	NC score	0.828975 (rank : 43)
Query Neighborhood Hits	997	Target Neighborhood Hits	324	Shared Neighborhood Hits	300
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

POTE8_HUMAN
θ value	1.68911e-14 (rank : 79)	NC score	0.759517 (rank : 131)
Query Neighborhood Hits	997	Target Neighborhood Hits	337	Shared Neighborhood Hits	283
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

ASB2_HUMAN
θ value	2.20605e-14 (rank : 80)	NC score	0.831326 (rank : 42)
Query Neighborhood Hits	997	Target Neighborhood Hits	309	Shared Neighborhood Hits	286
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ANKR2_MOUSE
θ value	2.88119e-14 (rank : 81)	NC score	0.835549 (rank : 36)
Query Neighborhood Hits	997	Target Neighborhood Hits	312	Shared Neighborhood Hits	287
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ANR11_HUMAN
θ value	2.88119e-14 (rank : 82)	NC score	0.749129 (rank : 136)
Query Neighborhood Hits	997	Target Neighborhood Hits	1289	Shared Neighborhood Hits	426
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ASB9_HUMAN
θ value	2.88119e-14 (rank : 83)	NC score	0.801292 (rank : 84)
Query Neighborhood Hits	997	Target Neighborhood Hits	267	Shared Neighborhood Hits	254
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

BCL3_MOUSE
θ value	2.88119e-14 (rank : 84)	NC score	0.827400 (rank : 45)
Query Neighborhood Hits	997	Target Neighborhood Hits	388	Shared Neighborhood Hits	323
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

CDN2C_HUMAN
θ value	2.88119e-14 (rank : 85)	NC score	0.825735 (rank : 53)
Query Neighborhood Hits	997	Target Neighborhood Hits	262	Shared Neighborhood Hits	261
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

NFKB1_HUMAN
θ value	2.88119e-14 (rank : 86)	NC score	0.711667 (rank : 156)
Query Neighborhood Hits	997	Target Neighborhood Hits	306	Shared Neighborhood Hits	276
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

PP16A_MOUSE
θ value	2.88119e-14 (rank : 87)	NC score	0.815527 (rank : 65)
Query Neighborhood Hits	997	Target Neighborhood Hits	318	Shared Neighborhood Hits	288
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

ANR12_HUMAN
θ value	3.76295e-14 (rank : 88)	NC score	0.703890 (rank : 160)
Query Neighborhood Hits	997	Target Neighborhood Hits	1081	Shared Neighborhood Hits	324
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

ANKR5_MOUSE
θ value	4.91457e-14 (rank : 89)	NC score	0.806459 (rank : 78)
Query Neighborhood Hits	997	Target Neighborhood Hits	298	Shared Neighborhood Hits	284
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ASB15_HUMAN
θ value	4.91457e-14 (rank : 90)	NC score	0.807139 (rank : 76)
Query Neighborhood Hits	997	Target Neighborhood Hits	305	Shared Neighborhood Hits	280
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

POT15_HUMAN
θ value	4.91457e-14 (rank : 91)	NC score	0.713397 (rank : 155)
Query Neighborhood Hits	997	Target Neighborhood Hits	893	Shared Neighborhood Hits	306
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

ANFY1_MOUSE
θ value	6.41864e-14 (rank : 92)	NC score	0.745191 (rank : 139)
Query Neighborhood Hits	997	Target Neighborhood Hits	480	Shared Neighborhood Hits	293
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANKS3_HUMAN
θ value	6.41864e-14 (rank : 93)	NC score	0.814141 (rank : 66)
Query Neighborhood Hits	997	Target Neighborhood Hits	355	Shared Neighborhood Hits	282
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ASB9_MOUSE
θ value	8.38298e-14 (rank : 94)	NC score	0.791954 (rank : 98)
Query Neighborhood Hits	997	Target Neighborhood Hits	257	Shared Neighborhood Hits	250
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

ZDH13_HUMAN
θ value	8.38298e-14 (rank : 95)	NC score	0.736326 (rank : 146)
Query Neighborhood Hits	997	Target Neighborhood Hits	322	Shared Neighborhood Hits	279
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

ANKS3_MOUSE
θ value	1.09485e-13 (rank : 96)	NC score	0.816176 (rank : 63)
Query Neighborhood Hits	997	Target Neighborhood Hits	355	Shared Neighborhood Hits	277
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

CDN2C_MOUSE
θ value	1.42992e-13 (rank : 97)	NC score	0.825045 (rank : 54)
Query Neighborhood Hits	997	Target Neighborhood Hits	270	Shared Neighborhood Hits	267
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

ANFY1_HUMAN
θ value	2.43908e-13 (rank : 98)	NC score	0.744006 (rank : 140)
Query Neighborhood Hits	997	Target Neighborhood Hits	480	Shared Neighborhood Hits	288
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANR15_HUMAN
θ value	2.43908e-13 (rank : 99)	NC score	0.732632 (rank : 148)
Query Neighborhood Hits	997	Target Neighborhood Hits	478	Shared Neighborhood Hits	294
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ANR18_HUMAN
θ value	2.43908e-13 (rank : 100)	NC score	0.601388 (rank : 193)
Query Neighborhood Hits	997	Target Neighborhood Hits	1106	Shared Neighborhood Hits	311
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ASB11_HUMAN
θ value	2.43908e-13 (rank : 101)	NC score	0.795500 (rank : 94)
Query Neighborhood Hits	997	Target Neighborhood Hits	271	Shared Neighborhood Hits	258
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ASB5_HUMAN
θ value	3.18553e-13 (rank : 102)	NC score	0.797456 (rank : 88)
Query Neighborhood Hits	997	Target Neighborhood Hits	283	Shared Neighborhood Hits	269
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ANKR2_HUMAN
θ value	4.16044e-13 (rank : 103)	NC score	0.832621 (rank : 39)
Query Neighborhood Hits	997	Target Neighborhood Hits	321	Shared Neighborhood Hits	288
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

ASB14_MOUSE
θ value	4.16044e-13 (rank : 104)	NC score	0.797240 (rank : 90)
Query Neighborhood Hits	997	Target Neighborhood Hits	293	Shared Neighborhood Hits	277
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

NOTC3_HUMAN
θ value	4.16044e-13 (rank : 105)	NC score	0.414127 (rank : 256)
Query Neighborhood Hits	997	Target Neighborhood Hits	1062	Shared Neighborhood Hits	385
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

AN30A_HUMAN
θ value	5.43371e-13 (rank : 106)	NC score	0.573757 (rank : 202)
Query Neighborhood Hits	997	Target Neighborhood Hits	1119	Shared Neighborhood Hits	337
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

IKBA_HUMAN
θ value	5.43371e-13 (rank : 107)	NC score	0.802245 (rank : 82)
Query Neighborhood Hits	997	Target Neighborhood Hits	280	Shared Neighborhood Hits	273
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

NOTC3_MOUSE
θ value	7.09661e-13 (rank : 108)	NC score	0.414478 (rank : 254)
Query Neighborhood Hits	997	Target Neighborhood Hits	975	Shared Neighborhood Hits	356
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

ANR39_HUMAN
θ value	9.26847e-13 (rank : 109)	NC score	0.838644 (rank : 34)
Query Neighborhood Hits	997	Target Neighborhood Hits	285	Shared Neighborhood Hits	280
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

PP16A_HUMAN
θ value	1.2105e-12 (rank : 110)	NC score	0.808351 (rank : 73)
Query Neighborhood Hits	997	Target Neighborhood Hits	340	Shared Neighborhood Hits	294
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

ASB16_MOUSE
θ value	2.0648e-12 (rank : 111)	NC score	0.811359 (rank : 67)
Query Neighborhood Hits	997	Target Neighborhood Hits	306	Shared Neighborhood Hits	280
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ILK_MOUSE
θ value	2.0648e-12 (rank : 112)	NC score	0.536725 (rank : 216)
Query Neighborhood Hits	997	Target Neighborhood Hits	858	Shared Neighborhood Hits	328
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

RN5A_MOUSE
θ value	2.0648e-12 (rank : 113)	NC score	0.740126 (rank : 143)
Query Neighborhood Hits	997	Target Neighborhood Hits	899	Shared Neighborhood Hits	335
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

BARD1_MOUSE
θ value	2.69671e-12 (rank : 114)	NC score	0.776361 (rank : 117)
Query Neighborhood Hits	997	Target Neighborhood Hits	411	Shared Neighborhood Hits	286
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

NFKB1_MOUSE
θ value	2.69671e-12 (rank : 115)	NC score	0.710253 (rank : 157)
Query Neighborhood Hits	997	Target Neighborhood Hits	300	Shared Neighborhood Hits	273
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

ILK1_HUMAN
θ value	3.52202e-12 (rank : 116)	NC score	0.537558 (rank : 215)
Query Neighborhood Hits	997	Target Neighborhood Hits	857	Shared Neighborhood Hits	328
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK2_HUMAN
θ value	3.52202e-12 (rank : 117)	NC score	0.554648 (rank : 211)
Query Neighborhood Hits	997	Target Neighborhood Hits	848	Shared Neighborhood Hits	328
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

ANR47_MOUSE
θ value	4.59992e-12 (rank : 118)	NC score	0.729014 (rank : 150)
Query Neighborhood Hits	997	Target Neighborhood Hits	350	Shared Neighborhood Hits	270
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

GABP2_MOUSE
θ value	4.59992e-12 (rank : 119)	NC score	0.820694 (rank : 57)
Query Neighborhood Hits	997	Target Neighborhood Hits	429	Shared Neighborhood Hits	290
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

ANR39_MOUSE
θ value	6.00763e-12 (rank : 120)	NC score	0.837293 (rank : 35)
Query Neighborhood Hits	997	Target Neighborhood Hits	284	Shared Neighborhood Hits	280
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

GABP2_HUMAN
θ value	6.00763e-12 (rank : 121)	NC score	0.818759 (rank : 58)
Query Neighborhood Hits	997	Target Neighborhood Hits	454	Shared Neighborhood Hits	288
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

IKBA_MOUSE
θ value	6.00763e-12 (rank : 122)	NC score	0.790670 (rank : 101)
Query Neighborhood Hits	997	Target Neighborhood Hits	283	Shared Neighborhood Hits	274
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

KRIT1_HUMAN
θ value	6.00763e-12 (rank : 123)	NC score	0.683739 (rank : 172)
Query Neighborhood Hits	997	Target Neighborhood Hits	258	Shared Neighborhood Hits	220
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

BARD1_HUMAN
θ value	7.84624e-12 (rank : 124)	NC score	0.778581 (rank : 115)
Query Neighborhood Hits	997	Target Neighborhood Hits	427	Shared Neighborhood Hits	290
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

NOTC1_HUMAN
θ value	7.84624e-12 (rank : 125)	NC score	0.406321 (rank : 262)
Query Neighborhood Hits	997	Target Neighborhood Hits	906	Shared Neighborhood Hits	315
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

POT14_HUMAN
θ value	1.02475e-11 (rank : 126)	NC score	0.700590 (rank : 165)
Query Neighborhood Hits	997	Target Neighborhood Hits	403	Shared Neighborhood Hits	276
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

UACA_HUMAN
θ value	1.02475e-11 (rank : 127)	NC score	0.488484 (rank : 233)
Query Neighborhood Hits	997	Target Neighborhood Hits	1622	Shared Neighborhood Hits	348
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

ANR23_MOUSE
θ value	1.33837e-11 (rank : 128)	NC score	0.831752 (rank : 41)
Query Neighborhood Hits	997	Target Neighborhood Hits	296	Shared Neighborhood Hits	285
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

AN36B_HUMAN
θ value	1.74796e-11 (rank : 129)	NC score	0.783293 (rank : 109)
Query Neighborhood Hits	997	Target Neighborhood Hits	294	Shared Neighborhood Hits	280
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

ASZ1_HUMAN
θ value	2.28291e-11 (rank : 130)	NC score	0.800322 (rank : 87)
Query Neighborhood Hits	997	Target Neighborhood Hits	341	Shared Neighborhood Hits	275
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

KRIT1_MOUSE
θ value	2.28291e-11 (rank : 131)	NC score	0.693245 (rank : 167)
Query Neighborhood Hits	997	Target Neighborhood Hits	258	Shared Neighborhood Hits	229
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

ANRA2_HUMAN
θ value	2.98157e-11 (rank : 132)	NC score	0.796664 (rank : 91)
Query Neighborhood Hits	997	Target Neighborhood Hits	288	Shared Neighborhood Hits	272
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

CDN2D_HUMAN
θ value	2.98157e-11 (rank : 133)	NC score	0.808577 (rank : 72)
Query Neighborhood Hits	997	Target Neighborhood Hits	268	Shared Neighborhood Hits	266
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

PA2G6_HUMAN
θ value	2.98157e-11 (rank : 134)	NC score	0.807295 (rank : 75)
Query Neighborhood Hits	997	Target Neighborhood Hits	284	Shared Neighborhood Hits	275
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

RN5A_HUMAN
θ value	2.98157e-11 (rank : 135)	NC score	0.783127 (rank : 110)
Query Neighborhood Hits	997	Target Neighborhood Hits	608	Shared Neighborhood Hits	306
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ANKR1_HUMAN
θ value	3.89403e-11 (rank : 136)	NC score	0.824558 (rank : 55)
Query Neighborhood Hits	997	Target Neighborhood Hits	308	Shared Neighborhood Hits	282
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ASB11_MOUSE
θ value	3.89403e-11 (rank : 137)	NC score	0.792417 (rank : 97)
Query Neighborhood Hits	997	Target Neighborhood Hits	271	Shared Neighborhood Hits	255
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ANKR1_MOUSE
θ value	5.08577e-11 (rank : 138)	NC score	0.822158 (rank : 56)
Query Neighborhood Hits	997	Target Neighborhood Hits	316	Shared Neighborhood Hits	286
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

ANKR5_HUMAN
θ value	5.08577e-11 (rank : 139)	NC score	0.801935 (rank : 83)
Query Neighborhood Hits	997	Target Neighborhood Hits	297	Shared Neighborhood Hits	282
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANR23_HUMAN
θ value	5.08577e-11 (rank : 140)	NC score	0.827697 (rank : 44)
Query Neighborhood Hits	997	Target Neighborhood Hits	291	Shared Neighborhood Hits	285
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

NFKB2_HUMAN
θ value	6.64225e-11 (rank : 141)	NC score	0.701829 (rank : 161)
Query Neighborhood Hits	997	Target Neighborhood Hits	325	Shared Neighborhood Hits	281
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

NOTC2_HUMAN
θ value	6.64225e-11 (rank : 142)	NC score	0.409594 (rank : 260)
Query Neighborhood Hits	997	Target Neighborhood Hits	1113	Shared Neighborhood Hits	406
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
θ value	8.67504e-11 (rank : 143)	NC score	0.405713 (rank : 263)
Query Neighborhood Hits	997	Target Neighborhood Hits	1069	Shared Neighborhood Hits	380
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

ANRA2_MOUSE
θ value	1.133e-10 (rank : 144)	NC score	0.793555 (rank : 96)
Query Neighborhood Hits	997	Target Neighborhood Hits	287	Shared Neighborhood Hits	271
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

GABP3_MOUSE
θ value	1.133e-10 (rank : 145)	NC score	0.818173 (rank : 59)
Query Neighborhood Hits	997	Target Neighborhood Hits	330	Shared Neighborhood Hits	277
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

ASB16_HUMAN
θ value	1.47974e-10 (rank : 146)	NC score	0.800797 (rank : 85)
Query Neighborhood Hits	997	Target Neighborhood Hits	286	Shared Neighborhood Hits	270
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

UACA_MOUSE
θ value	1.47974e-10 (rank : 147)	NC score	0.463294 (rank : 244)
Query Neighborhood Hits	997	Target Neighborhood Hits	1620	Shared Neighborhood Hits	351
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

NFKB2_MOUSE
θ value	1.9326e-10 (rank : 148)	NC score	0.686088 (rank : 170)
Query Neighborhood Hits	997	Target Neighborhood Hits	326	Shared Neighborhood Hits	282
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ANR38_HUMAN
θ value	4.30538e-10 (rank : 149)	NC score	0.672025 (rank : 176)
Query Neighborhood Hits	997	Target Neighborhood Hits	443	Shared Neighborhood Hits	262
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ANR19_HUMAN
θ value	5.62301e-10 (rank : 150)	NC score	0.751793 (rank : 133)
Query Neighborhood Hits	997	Target Neighborhood Hits	276	Shared Neighborhood Hits	272
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

IKBB_HUMAN
θ value	5.62301e-10 (rank : 151)	NC score	0.767282 (rank : 127)
Query Neighborhood Hits	997	Target Neighborhood Hits	284	Shared Neighborhood Hits	274
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

NFH_MOUSE
θ value	5.62301e-10 (rank : 152)	NC score	0.108204 (rank : 399)
Query Neighborhood Hits	997	Target Neighborhood Hits	2247	Shared Neighborhood Hits	420
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NOTC1_MOUSE
θ value	5.62301e-10 (rank : 153)	NC score	0.347781 (rank : 270)
Query Neighborhood Hits	997	Target Neighborhood Hits	916	Shared Neighborhood Hits	300
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

ANR25_HUMAN
θ value	7.34386e-10 (rank : 154)	NC score	0.688212 (rank : 169)
Query Neighborhood Hits	997	Target Neighborhood Hits	350	Shared Neighborhood Hits	277
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

ANR38_MOUSE
θ value	7.34386e-10 (rank : 155)	NC score	0.647917 (rank : 183)
Query Neighborhood Hits	997	Target Neighborhood Hits	512	Shared Neighborhood Hits	262
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

IKBB_MOUSE
θ value	7.34386e-10 (rank : 156)	NC score	0.770128 (rank : 125)
Query Neighborhood Hits	997	Target Neighborhood Hits	284	Shared Neighborhood Hits	276
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

ANR10_MOUSE
θ value	1.25267e-09 (rank : 157)	NC score	0.787409 (rank : 104)
Query Neighborhood Hits	997	Target Neighborhood Hits	273	Shared Neighborhood Hits	263
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANR32_HUMAN
θ value	1.25267e-09 (rank : 158)	NC score	0.762775 (rank : 128)
Query Neighborhood Hits	997	Target Neighborhood Hits	270	Shared Neighborhood Hits	257
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

USH1G_HUMAN
θ value	1.63604e-09 (rank : 159)	NC score	0.751574 (rank : 134)
Query Neighborhood Hits	997	Target Neighborhood Hits	267	Shared Neighborhood Hits	261
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

USH1G_MOUSE
θ value	1.63604e-09 (rank : 160)	NC score	0.751417 (rank : 135)
Query Neighborhood Hits	997	Target Neighborhood Hits	271	Shared Neighborhood Hits	261
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

IKBE_MOUSE
θ value	2.13673e-09 (rank : 161)	NC score	0.790846 (rank : 100)
Query Neighborhood Hits	997	Target Neighborhood Hits	308	Shared Neighborhood Hits	280
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

ANR25_MOUSE
θ value	2.79066e-09 (rank : 162)	NC score	0.678965 (rank : 175)
Query Neighborhood Hits	997	Target Neighborhood Hits	398	Shared Neighborhood Hits	297
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

SHAN1_HUMAN
θ value	3.64472e-09 (rank : 163)	NC score	0.739106 (rank : 144)
Query Neighborhood Hits	997	Target Neighborhood Hits	1041	Shared Neighborhood Hits	505
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

ANR47_HUMAN
θ value	4.76016e-09 (rank : 164)	NC score	0.707521 (rank : 158)
Query Neighborhood Hits	997	Target Neighborhood Hits	369	Shared Neighborhood Hits	273
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

IKBE_HUMAN
θ value	4.76016e-09 (rank : 165)	NC score	0.772711 (rank : 121)
Query Neighborhood Hits	997	Target Neighborhood Hits	288	Shared Neighborhood Hits	271
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

MLL3_MOUSE
θ value	8.11959e-09 (rank : 166)	NC score	0.126342 (rank : 345)
Query Neighborhood Hits	997	Target Neighborhood Hits	1399	Shared Neighborhood Hits	299
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

ASB12_HUMAN
θ value	1.06045e-08 (rank : 167)	NC score	0.771388 (rank : 123)
Query Neighborhood Hits	997	Target Neighborhood Hits	263	Shared Neighborhood Hits	262
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ASZ1_MOUSE
θ value	1.38499e-08 (rank : 168)	NC score	0.796058 (rank : 92)
Query Neighborhood Hits	997	Target Neighborhood Hits	319	Shared Neighborhood Hits	279
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

EPHA5_HUMAN
θ value	1.38499e-08 (rank : 169)	NC score	0.113625 (rank : 367)
Query Neighborhood Hits	997	Target Neighborhood Hits	1009	Shared Neighborhood Hits	112
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

A20A2_HUMAN
θ value	1.80886e-08 (rank : 170)	NC score	0.638626 (rank : 186)
Query Neighborhood Hits	997	Target Neighborhood Hits	716	Shared Neighborhood Hits	298
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

ASB12_MOUSE
θ value	1.80886e-08 (rank : 171)	NC score	0.775716 (rank : 119)
Query Neighborhood Hits	997	Target Neighborhood Hits	261	Shared Neighborhood Hits	258
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

CDN2D_MOUSE
θ value	1.80886e-08 (rank : 172)	NC score	0.797451 (rank : 89)
Query Neighborhood Hits	997	Target Neighborhood Hits	267	Shared Neighborhood Hits	264
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

OSTF1_MOUSE
θ value	1.80886e-08 (rank : 173)	NC score	0.649616 (rank : 180)
Query Neighborhood Hits	997	Target Neighborhood Hits	467	Shared Neighborhood Hits	301
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

ASB4_HUMAN
θ value	2.36244e-08 (rank : 174)	NC score	0.780135 (rank : 112)
Query Neighborhood Hits	997	Target Neighborhood Hits	264	Shared Neighborhood Hits	258
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

A20A1_HUMAN
θ value	3.08544e-08 (rank : 175)	NC score	0.637899 (rank : 187)
Query Neighborhood Hits	997	Target Neighborhood Hits	698	Shared Neighborhood Hits	292
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

A20A3_HUMAN
θ value	4.0297e-08 (rank : 176)	NC score	0.639350 (rank : 185)
Query Neighborhood Hits	997	Target Neighborhood Hits	692	Shared Neighborhood Hits	295
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A4_HUMAN
θ value	4.0297e-08 (rank : 177)	NC score	0.634711 (rank : 189)
Query Neighborhood Hits	997	Target Neighborhood Hits	710	Shared Neighborhood Hits	296
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

ANR10_HUMAN
θ value	4.0297e-08 (rank : 178)	NC score	0.786881 (rank : 107)
Query Neighborhood Hits	997	Target Neighborhood Hits	289	Shared Neighborhood Hits	266
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ASB4_MOUSE
θ value	4.0297e-08 (rank : 179)	NC score	0.779357 (rank : 113)
Query Neighborhood Hits	997	Target Neighborhood Hits	265	Shared Neighborhood Hits	259
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

RFXK_HUMAN
θ value	4.0297e-08 (rank : 180)	NC score	0.787168 (rank : 105)
Query Neighborhood Hits	997	Target Neighborhood Hits	282	Shared Neighborhood Hits	266
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

ACBD6_MOUSE
θ value	6.87365e-08 (rank : 181)	NC score	0.773226 (rank : 120)
Query Neighborhood Hits	997	Target Neighborhood Hits	305	Shared Neighborhood Hits	285
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANR26_MOUSE
θ value	6.87365e-08 (rank : 182)	NC score	0.443020 (rank : 249)
Query Neighborhood Hits	997	Target Neighborhood Hits	1554	Shared Neighborhood Hits	344
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ASB8_MOUSE
θ value	8.97725e-08 (rank : 183)	NC score	0.816710 (rank : 62)
Query Neighborhood Hits	997	Target Neighborhood Hits	293	Shared Neighborhood Hits	281
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

EPHA2_HUMAN
θ value	8.97725e-08 (rank : 184)	NC score	0.109476 (rank : 393)
Query Neighborhood Hits	997	Target Neighborhood Hits	1021	Shared Neighborhood Hits	108
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

OSTF1_HUMAN
θ value	8.97725e-08 (rank : 185)	NC score	0.632259 (rank : 190)
Query Neighborhood Hits	997	Target Neighborhood Hits	466	Shared Neighborhood Hits	299
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

ABTB2_MOUSE
θ value	1.17247e-07 (rank : 186)	NC score	0.561338 (rank : 208)
Query Neighborhood Hits	997	Target Neighborhood Hits	414	Shared Neighborhood Hits	237
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ACBD6_HUMAN
θ value	1.17247e-07 (rank : 187)	NC score	0.769264 (rank : 126)
Query Neighborhood Hits	997	Target Neighborhood Hits	304	Shared Neighborhood Hits	285
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANKY2_MOUSE
θ value	1.17247e-07 (rank : 188)	NC score	0.704554 (rank : 159)
Query Neighborhood Hits	997	Target Neighborhood Hits	316	Shared Neighborhood Hits	264
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ASB8_HUMAN
θ value	1.17247e-07 (rank : 189)	NC score	0.815912 (rank : 64)
Query Neighborhood Hits	997	Target Neighborhood Hits	294	Shared Neighborhood Hits	284
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

POT22_HUMAN
θ value	1.17247e-07 (rank : 190)	NC score	0.660979 (rank : 178)
Query Neighborhood Hits	997	Target Neighborhood Hits	266	Shared Neighborhood Hits	255
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

ANR26_HUMAN
θ value	1.53129e-07 (rank : 191)	NC score	0.423764 (rank : 252)
Query Neighborhood Hits	997	Target Neighborhood Hits	1614	Shared Neighborhood Hits	345
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ANR32_MOUSE
θ value	1.53129e-07 (rank : 192)	NC score	0.748060 (rank : 137)
Query Neighborhood Hits	997	Target Neighborhood Hits	285	Shared Neighborhood Hits	257
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

BCOR_MOUSE
θ value	1.53129e-07 (rank : 193)	NC score	0.701084 (rank : 164)
Query Neighborhood Hits	997	Target Neighborhood Hits	521	Shared Neighborhood Hits	329
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

RGS3_HUMAN
θ value	1.99992e-07 (rank : 194)	NC score	0.100786 (rank : 419)
Query Neighborhood Hits	997	Target Neighborhood Hits	1375	Shared Neighborhood Hits	335
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

ABTB2_HUMAN
θ value	2.61198e-07 (rank : 195)	NC score	0.572859 (rank : 204)
Query Neighborhood Hits	997	Target Neighborhood Hits	391	Shared Neighborhood Hits	237
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ANKR7_HUMAN
θ value	2.61198e-07 (rank : 196)	NC score	0.794532 (rank : 95)
Query Neighborhood Hits	997	Target Neighborhood Hits	286	Shared Neighborhood Hits	278
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

ANR46_MOUSE
θ value	2.61198e-07 (rank : 197)	NC score	0.782567 (rank : 111)
Query Neighborhood Hits	997	Target Neighborhood Hits	274	Shared Neighborhood Hits	269
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

EPHA2_MOUSE
θ value	2.61198e-07 (rank : 198)	NC score	0.109464 (rank : 394)
Query Neighborhood Hits	997	Target Neighborhood Hits	1020	Shared Neighborhood Hits	108
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

EPHB2_HUMAN
θ value	2.61198e-07 (rank : 199)	NC score	0.109854 (rank : 390)
Query Neighborhood Hits	997	Target Neighborhood Hits	983	Shared Neighborhood Hits	106
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

OGFR_HUMAN
θ value	2.61198e-07 (rank : 200)	NC score	0.166160 (rank : 307)
Query Neighborhood Hits	997	Target Neighborhood Hits	1582	Shared Neighborhood Hits	420
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

ANR49_MOUSE
θ value	3.41135e-07 (rank : 201)	NC score	0.809366 (rank : 70)
Query Neighborhood Hits	997	Target Neighborhood Hits	285	Shared Neighborhood Hits	273
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ANS4B_HUMAN
θ value	3.41135e-07 (rank : 202)	NC score	0.741390 (rank : 141)
Query Neighborhood Hits	997	Target Neighborhood Hits	289	Shared Neighborhood Hits	259
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

BCOR_HUMAN
θ value	3.41135e-07 (rank : 203)	NC score	0.694942 (rank : 166)
Query Neighborhood Hits	997	Target Neighborhood Hits	609	Shared Neighborhood Hits	353
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

EPHA1_MOUSE
θ value	3.41135e-07 (rank : 204)	NC score	0.110384 (rank : 386)
Query Neighborhood Hits	997	Target Neighborhood Hits	958	Shared Neighborhood Hits	105
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

HECD1_HUMAN
θ value	3.41135e-07 (rank : 205)	NC score	0.588336 (rank : 199)
Query Neighborhood Hits	997	Target Neighborhood Hits	371	Shared Neighborhood Hits	277
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

MPP8_HUMAN
θ value	3.41135e-07 (rank : 206)	NC score	0.648297 (rank : 182)
Query Neighborhood Hits	997	Target Neighborhood Hits	948	Shared Neighborhood Hits	298
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

ANKY2_HUMAN
θ value	4.45536e-07 (rank : 207)	NC score	0.725517 (rank : 152)
Query Neighborhood Hits	997	Target Neighborhood Hits	306	Shared Neighborhood Hits	262
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

EPHA1_HUMAN
θ value	4.45536e-07 (rank : 208)	NC score	0.110313 (rank : 387)
Query Neighborhood Hits	997	Target Neighborhood Hits	997	Shared Neighborhood Hits	113
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

EPHA7_HUMAN
θ value	4.45536e-07 (rank : 209)	NC score	0.111422 (rank : 377)
Query Neighborhood Hits	997	Target Neighborhood Hits	1053	Shared Neighborhood Hits	112
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

K1802_MOUSE
θ value	4.45536e-07 (rank : 210)	NC score	0.117405 (rank : 360)
Query Neighborhood Hits	997	Target Neighborhood Hits	1596	Shared Neighborhood Hits	333
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

NACAM_MOUSE
θ value	4.45536e-07 (rank : 211)	NC score	0.174498 (rank : 302)
Query Neighborhood Hits	997	Target Neighborhood Hits	1866	Shared Neighborhood Hits	448
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

EPHA5_MOUSE
θ value	5.81887e-07 (rank : 212)	NC score	0.103232 (rank : 413)
Query Neighborhood Hits	997	Target Neighborhood Hits	950	Shared Neighborhood Hits	101
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

ASPP2_HUMAN
θ value	7.59969e-07 (rank : 213)	NC score	0.566568 (rank : 206)
Query Neighborhood Hits	997	Target Neighborhood Hits	1156	Shared Neighborhood Hits	412
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

CT086_HUMAN
θ value	7.59969e-07 (rank : 214)	NC score	0.789164 (rank : 103)
Query Neighborhood Hits	997	Target Neighborhood Hits	277	Shared Neighborhood Hits	272
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

AN36A_HUMAN
θ value	9.92553e-07 (rank : 215)	NC score	0.740622 (rank : 142)
Query Neighborhood Hits	997	Target Neighborhood Hits	271	Shared Neighborhood Hits	268
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ANR33_MOUSE
θ value	9.92553e-07 (rank : 216)	NC score	0.685114 (rank : 171)
Query Neighborhood Hits	997	Target Neighborhood Hits	225	Shared Neighborhood Hits	223
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

EPHA7_MOUSE
θ value	9.92553e-07 (rank : 217)	NC score	0.110313 (rank : 388)
Query Neighborhood Hits	997	Target Neighborhood Hits	1025	Shared Neighborhood Hits	104
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

ZN516_MOUSE
θ value	9.92553e-07 (rank : 218)	NC score	0.017086 (rank : 1185)
Query Neighborhood Hits	997	Target Neighborhood Hits	1197	Shared Neighborhood Hits	230
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

RFXK_MOUSE
θ value	1.29631e-06 (rank : 219)	NC score	0.770749 (rank : 124)
Query Neighborhood Hits	997	Target Neighborhood Hits	273	Shared Neighborhood Hits	265
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

ANR46_HUMAN
θ value	1.69304e-06 (rank : 220)	NC score	0.787121 (rank : 106)
Query Neighborhood Hits	997	Target Neighborhood Hits	281	Shared Neighborhood Hits	276
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ANS4B_MOUSE
θ value	2.21117e-06 (rank : 221)	NC score	0.728716 (rank : 151)
Query Neighborhood Hits	997	Target Neighborhood Hits	294	Shared Neighborhood Hits	256
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

EPHB4_HUMAN
θ value	2.21117e-06 (rank : 222)	NC score	0.110537 (rank : 381)
Query Neighborhood Hits	997	Target Neighborhood Hits	1056	Shared Neighborhood Hits	117
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

MDC1_HUMAN
θ value	2.21117e-06 (rank : 223)	NC score	0.154311 (rank : 315)
Query Neighborhood Hits	997	Target Neighborhood Hits	1446	Shared Neighborhood Hits	321
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

AN13B_HUMAN
θ value	2.88788e-06 (rank : 224)	NC score	0.527099 (rank : 222)
Query Neighborhood Hits	997	Target Neighborhood Hits	265	Shared Neighborhood Hits	253
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13B_MOUSE
θ value	2.88788e-06 (rank : 225)	NC score	0.527874 (rank : 221)
Query Neighborhood Hits	997	Target Neighborhood Hits	276	Shared Neighborhood Hits	254
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

ANR37_MOUSE
θ value	2.88788e-06 (rank : 226)	NC score	0.701572 (rank : 163)
Query Neighborhood Hits	997	Target Neighborhood Hits	237	Shared Neighborhood Hits	234
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

EPHB4_MOUSE
θ value	2.88788e-06 (rank : 227)	NC score	0.109067 (rank : 396)
Query Neighborhood Hits	997	Target Neighborhood Hits	1013	Shared Neighborhood Hits	112
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

ASB1_MOUSE
θ value	3.77169e-06 (rank : 228)	NC score	0.762021 (rank : 130)
Query Neighborhood Hits	997	Target Neighborhood Hits	292	Shared Neighborhood Hits	271
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ANR49_HUMAN
θ value	4.92598e-06 (rank : 229)	NC score	0.804071 (rank : 81)
Query Neighborhood Hits	997	Target Neighborhood Hits	282	Shared Neighborhood Hits	273
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

MAGE1_HUMAN
θ value	6.43352e-06 (rank : 230)	NC score	0.123332 (rank : 351)
Query Neighborhood Hits	997	Target Neighborhood Hits	1389	Shared Neighborhood Hits	381
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

AN13A_HUMAN
θ value	8.40245e-06 (rank : 231)	NC score	0.464227 (rank : 242)
Query Neighborhood Hits	997	Target Neighborhood Hits	243	Shared Neighborhood Hits	223
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

DGKI_HUMAN
θ value	8.40245e-06 (rank : 232)	NC score	0.350742 (rank : 268)
Query Neighborhood Hits	997	Target Neighborhood Hits	609	Shared Neighborhood Hits	223
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

EPHB3_HUMAN
θ value	8.40245e-06 (rank : 233)	NC score	0.110439 (rank : 383)
Query Neighborhood Hits	997	Target Neighborhood Hits	996	Shared Neighborhood Hits	111
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

ASB1_HUMAN
θ value	1.09739e-05 (rank : 234)	NC score	0.762397 (rank : 129)
Query Neighborhood Hits	997	Target Neighborhood Hits	291	Shared Neighborhood Hits	271
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

EPHB1_HUMAN
θ value	1.09739e-05 (rank : 235)	NC score	0.107019 (rank : 401)
Query Neighborhood Hits	997	Target Neighborhood Hits	988	Shared Neighborhood Hits	106
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

EPHB2_MOUSE
θ value	1.09739e-05 (rank : 236)	NC score	0.108207 (rank : 398)
Query Neighborhood Hits	997	Target Neighborhood Hits	982	Shared Neighborhood Hits	106
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

PRRT3_HUMAN
θ value	1.43324e-05 (rank : 237)	NC score	0.160447 (rank : 311)
Query Neighborhood Hits	997	Target Neighborhood Hits	998	Shared Neighborhood Hits	331
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

ASPP1_MOUSE
θ value	1.87187e-05 (rank : 238)	NC score	0.557324 (rank : 210)
Query Neighborhood Hits	997	Target Neighborhood Hits	1244	Shared Neighborhood Hits	491
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CEL_HUMAN
θ value	1.87187e-05 (rank : 239)	NC score	0.093928 (rank : 445)
Query Neighborhood Hits	997	Target Neighborhood Hits	896	Shared Neighborhood Hits	296
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CENB5_HUMAN
θ value	1.87187e-05 (rank : 240)	NC score	0.533673 (rank : 218)
Query Neighborhood Hits	997	Target Neighborhood Hits	395	Shared Neighborhood Hits	271
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CT012_MOUSE
θ value	1.87187e-05 (rank : 241)	NC score	0.467774 (rank : 238)
Query Neighborhood Hits	997	Target Neighborhood Hits	229	Shared Neighborhood Hits	183
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

ANR37_HUMAN
θ value	2.44474e-05 (rank : 242)	NC score	0.718118 (rank : 153)
Query Neighborhood Hits	997	Target Neighborhood Hits	247	Shared Neighborhood Hits	244
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

TRPV5_MOUSE
θ value	2.44474e-05 (rank : 243)	NC score	0.484927 (rank : 234)
Query Neighborhood Hits	997	Target Neighborhood Hits	278	Shared Neighborhood Hits	246
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

ASPP1_HUMAN
θ value	3.19293e-05 (rank : 244)	NC score	0.562044 (rank : 207)
Query Neighborhood Hits	997	Target Neighborhood Hits	956	Shared Neighborhood Hits	387
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

EPHB3_MOUSE
θ value	3.19293e-05 (rank : 245)	NC score	0.109317 (rank : 395)
Query Neighborhood Hits	997	Target Neighborhood Hits	996	Shared Neighborhood Hits	108
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

ANR22_HUMAN
θ value	4.1701e-05 (rank : 246)	NC score	0.778405 (rank : 116)
Query Neighborhood Hits	997	Target Neighborhood Hits	243	Shared Neighborhood Hits	240
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

CENB2_HUMAN
θ value	4.1701e-05 (rank : 247)	NC score	0.520129 (rank : 224)
Query Neighborhood Hits	997	Target Neighborhood Hits	425	Shared Neighborhood Hits	262
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

DDEF2_HUMAN
θ value	4.1701e-05 (rank : 248)	NC score	0.414253 (rank : 255)
Query Neighborhood Hits	997	Target Neighborhood Hits	599	Shared Neighborhood Hits	350
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	4.1701e-05 (rank : 249)	NC score	0.410263 (rank : 259)
Query Neighborhood Hits	997	Target Neighborhood Hits	625	Shared Neighborhood Hits	357
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

GIT1_HUMAN
θ value	4.1701e-05 (rank : 250)	NC score	0.482616 (rank : 236)
Query Neighborhood Hits	997	Target Neighborhood Hits	336	Shared Neighborhood Hits	252
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

GIT1_MOUSE
θ value	4.1701e-05 (rank : 251)	NC score	0.483497 (rank : 235)
Query Neighborhood Hits	997	Target Neighborhood Hits	341	Shared Neighborhood Hits	251
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

RSNL2_HUMAN
θ value	4.1701e-05 (rank : 252)	NC score	0.261271 (rank : 282)
Query Neighborhood Hits	997	Target Neighborhood Hits	136	Shared Neighborhood Hits	115
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

TRPV6_MOUSE
θ value	4.1701e-05 (rank : 253)	NC score	0.531366 (rank : 220)
Query Neighborhood Hits	997	Target Neighborhood Hits	284	Shared Neighborhood Hits	254
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

ANR41_HUMAN
θ value	5.44631e-05 (rank : 254)	NC score	0.732066 (rank : 149)
Query Neighborhood Hits	997	Target Neighborhood Hits	332	Shared Neighborhood Hits	284
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

RGS3_MOUSE
θ value	5.44631e-05 (rank : 255)	NC score	0.132514 (rank : 333)
Query Neighborhood Hits	997	Target Neighborhood Hits	1621	Shared Neighborhood Hits	408
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SON_HUMAN
θ value	5.44631e-05 (rank : 256)	NC score	0.143439 (rank : 323)
Query Neighborhood Hits	997	Target Neighborhood Hits	1568	Shared Neighborhood Hits	411
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

AN13A_MOUSE
θ value	7.1131e-05 (rank : 257)	NC score	0.440924 (rank : 250)
Query Neighborhood Hits	997	Target Neighborhood Hits	226	Shared Neighborhood Hits	214
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

CD2A1_MOUSE
θ value	7.1131e-05 (rank : 258)	NC score	0.679450 (rank : 174)
Query Neighborhood Hits	997	Target Neighborhood Hits	206	Shared Neighborhood Hits	204
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

IASPP_MOUSE
θ value	7.1131e-05 (rank : 259)	NC score	0.537621 (rank : 214)
Query Neighborhood Hits	997	Target Neighborhood Hits	1024	Shared Neighborhood Hits	512
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

MLL3_HUMAN
θ value	7.1131e-05 (rank : 260)	NC score	0.130888 (rank : 336)
Query Neighborhood Hits	997	Target Neighborhood Hits	1644	Shared Neighborhood Hits	342
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

WASIP_HUMAN
θ value	7.1131e-05 (rank : 261)	NC score	0.210151 (rank : 294)
Query Neighborhood Hits	997	Target Neighborhood Hits	458	Shared Neighborhood Hits	219
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

FA47A_HUMAN
θ value	9.29e-05 (rank : 262)	NC score	0.110992 (rank : 378)
Query Neighborhood Hits	997	Target Neighborhood Hits	451	Shared Neighborhood Hits	148
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

GIT2_HUMAN
θ value	9.29e-05 (rank : 263)	NC score	0.465564 (rank : 240)
Query Neighborhood Hits	997	Target Neighborhood Hits	381	Shared Neighborhood Hits	255
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

MARK2_HUMAN
θ value	9.29e-05 (rank : 264)	NC score	0.048183 (rank : 954)
Query Neighborhood Hits	997	Target Neighborhood Hits	1056	Shared Neighborhood Hits	139
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

NCOA6_HUMAN
θ value	9.29e-05 (rank : 265)	NC score	0.150209 (rank : 318)
Query Neighborhood Hits	997	Target Neighborhood Hits	1202	Shared Neighborhood Hits	354
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

RTP3_MOUSE
θ value	9.29e-05 (rank : 266)	NC score	0.107216 (rank : 400)
Query Neighborhood Hits	997	Target Neighborhood Hits	374	Shared Neighborhood Hits	137
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

LCP2_HUMAN
θ value	0.000121331 (rank : 267)	NC score	0.110396 (rank : 384)
Query Neighborhood Hits	997	Target Neighborhood Hits	531	Shared Neighborhood Hits	183
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

MDC1_MOUSE
θ value	0.000121331 (rank : 268)	NC score	0.140099 (rank : 327)
Query Neighborhood Hits	997	Target Neighborhood Hits	998	Shared Neighborhood Hits	275
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

PCLO_MOUSE
θ value	0.000121331 (rank : 269)	NC score	0.131853 (rank : 334)
Query Neighborhood Hits	997	Target Neighborhood Hits	2275	Shared Neighborhood Hits	490
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

EPHA8_MOUSE
θ value	0.000158464 (rank : 270)	NC score	0.108696 (rank : 397)
Query Neighborhood Hits	997	Target Neighborhood Hits	969	Shared Neighborhood Hits	101
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

GIT2_MOUSE
θ value	0.000158464 (rank : 271)	NC score	0.499596 (rank : 232)
Query Neighborhood Hits	997	Target Neighborhood Hits	323	Shared Neighborhood Hits	260
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

DDFL1_MOUSE
θ value	0.00020696 (rank : 272)	NC score	0.467543 (rank : 239)
Query Neighborhood Hits	997	Target Neighborhood Hits	324	Shared Neighborhood Hits	257
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

EPHA4_MOUSE
θ value	0.00020696 (rank : 273)	NC score	0.105400 (rank : 407)
Query Neighborhood Hits	997	Target Neighborhood Hits	982	Shared Neighborhood Hits	100
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

ANR33_HUMAN
θ value	0.000270298 (rank : 274)	NC score	0.660810 (rank : 179)
Query Neighborhood Hits	997	Target Neighborhood Hits	215	Shared Neighborhood Hits	212
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

EPHA6_HUMAN
θ value	0.000270298 (rank : 275)	NC score	0.112030 (rank : 373)
Query Neighborhood Hits	997	Target Neighborhood Hits	959	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

MAST4_HUMAN
θ value	0.000270298 (rank : 276)	NC score	0.065860 (rank : 625)
Query Neighborhood Hits	997	Target Neighborhood Hits	1804	Shared Neighborhood Hits	340
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

SNCAP_HUMAN
θ value	0.000270298 (rank : 277)	NC score	0.701613 (rank : 162)
Query Neighborhood Hits	997	Target Neighborhood Hits	313	Shared Neighborhood Hits	254
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

TULP4_HUMAN
θ value	0.000270298 (rank : 278)	NC score	0.066320 (rank : 616)
Query Neighborhood Hits	997	Target Neighborhood Hits	426	Shared Neighborhood Hits	109
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

DDEF1_MOUSE
θ value	0.00035302 (rank : 279)	NC score	0.327213 (rank : 274)
Query Neighborhood Hits	997	Target Neighborhood Hits	592	Shared Neighborhood Hits	300
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

EPHA4_HUMAN
θ value	0.00035302 (rank : 280)	NC score	0.105129 (rank : 409)
Query Neighborhood Hits	997	Target Neighborhood Hits	975	Shared Neighborhood Hits	100
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

EPHA8_HUMAN
θ value	0.00035302 (rank : 281)	NC score	0.106642 (rank : 404)
Query Neighborhood Hits	997	Target Neighborhood Hits	956	Shared Neighborhood Hits	100
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

ANR45_MOUSE
θ value	0.000461057 (rank : 282)	NC score	0.598431 (rank : 195)
Query Neighborhood Hits	997	Target Neighborhood Hits	204	Shared Neighborhood Hits	189
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

MTPN_MOUSE
θ value	0.000461057 (rank : 283)	NC score	0.791173 (rank : 99)
Query Neighborhood Hits	997	Target Neighborhood Hits	269	Shared Neighborhood Hits	264
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

EPHB6_HUMAN
θ value	0.000602161 (rank : 284)	NC score	0.115693 (rank : 365)
Query Neighborhood Hits	997	Target Neighborhood Hits	912	Shared Neighborhood Hits	111
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

TEX14_MOUSE
θ value	0.000602161 (rank : 285)	NC score	0.411050 (rank : 258)
Query Neighborhood Hits	997	Target Neighborhood Hits	1333	Shared Neighborhood Hits	337
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

CD248_HUMAN
θ value	0.000786445 (rank : 286)	NC score	0.075575 (rank : 532)
Query Neighborhood Hits	997	Target Neighborhood Hits	679	Shared Neighborhood Hits	171
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CNTRB_MOUSE
θ value	0.000786445 (rank : 287)	NC score	0.053460 (rank : 839)
Query Neighborhood Hits	997	Target Neighborhood Hits	1029	Shared Neighborhood Hits	130
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CAMKV_HUMAN
θ value	0.00102713 (rank : 288)	NC score	0.038201 (rank : 1021)
Query Neighborhood Hits	997	Target Neighborhood Hits	1084	Shared Neighborhood Hits	166
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

EPHAA_HUMAN
θ value	0.00102713 (rank : 289)	NC score	0.110389 (rank : 385)
Query Neighborhood Hits	997	Target Neighborhood Hits	960	Shared Neighborhood Hits	103
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

GLSL_MOUSE
θ value	0.00102713 (rank : 290)	NC score	0.503638 (rank : 230)
Query Neighborhood Hits	997	Target Neighborhood Hits	212	Shared Neighborhood Hits	202
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

HSF1_MOUSE
θ value	0.00102713 (rank : 291)	NC score	0.058617 (rank : 759)
Query Neighborhood Hits	997	Target Neighborhood Hits	267	Shared Neighborhood Hits	78
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

SARM1_MOUSE
θ value	0.00102713 (rank : 292)	NC score	0.100577 (rank : 420)
Query Neighborhood Hits	997	Target Neighborhood Hits	54	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PDS3, Q5SYG5, Q5SYG6, Q6A054, Q6SZW0, Q8BRI9	Gene names	Sarm1, Kiaa0524
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Tir-1 homolog).

EPHA6_MOUSE
θ value	0.00134147 (rank : 293)	NC score	0.110657 (rank : 380)
Query Neighborhood Hits	997	Target Neighborhood Hits	946	Shared Neighborhood Hits	94
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

GA2L2_MOUSE
θ value	0.00134147 (rank : 294)	NC score	0.070726 (rank : 578)
Query Neighborhood Hits	997	Target Neighborhood Hits	395	Shared Neighborhood Hits	154
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

MTPN_HUMAN
θ value	0.00134147 (rank : 295)	NC score	0.786449 (rank : 108)
Query Neighborhood Hits	997	Target Neighborhood Hits	269	Shared Neighborhood Hits	264
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

RSNL2_MOUSE
θ value	0.00134147 (rank : 296)	NC score	0.221718 (rank : 287)
Query Neighborhood Hits	997	Target Neighborhood Hits	129	Shared Neighborhood Hits	99
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

SASH1_MOUSE
θ value	0.00134147 (rank : 297)	NC score	0.136008 (rank : 331)
Query Neighborhood Hits	997	Target Neighborhood Hits	263	Shared Neighborhood Hits	120
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

CECR2_HUMAN
θ value	0.00175202 (rank : 298)	NC score	0.075377 (rank : 534)
Query Neighborhood Hits	997	Target Neighborhood Hits	543	Shared Neighborhood Hits	179
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

CLPB_MOUSE
θ value	0.00175202 (rank : 299)	NC score	0.644880 (rank : 184)
Query Neighborhood Hits	997	Target Neighborhood Hits	289	Shared Neighborhood Hits	258
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

CT012_HUMAN
θ value	0.00175202 (rank : 300)	NC score	0.425448 (rank : 251)
Query Neighborhood Hits	997	Target Neighborhood Hits	205	Shared Neighborhood Hits	166
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

DDFL1_HUMAN
θ value	0.00175202 (rank : 301)	NC score	0.378042 (rank : 264)
Query Neighborhood Hits	997	Target Neighborhood Hits	353	Shared Neighborhood Hits	254
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

GLSL_HUMAN
θ value	0.00175202 (rank : 302)	NC score	0.507678 (rank : 229)
Query Neighborhood Hits	997	Target Neighborhood Hits	211	Shared Neighborhood Hits	202
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

TARSH_HUMAN
θ value	0.00175202 (rank : 303)	NC score	0.150745 (rank : 317)
Query Neighborhood Hits	997	Target Neighborhood Hits	768	Shared Neighborhood Hits	265
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

PHC2_HUMAN
θ value	0.00228821 (rank : 304)	NC score	0.067231 (rank : 605)
Query Neighborhood Hits	997	Target Neighborhood Hits	388	Shared Neighborhood Hits	149
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

TEX14_HUMAN
θ value	0.00228821 (rank : 305)	NC score	0.413700 (rank : 257)
Query Neighborhood Hits	997	Target Neighborhood Hits	1103	Shared Neighborhood Hits	333
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TRPV1_MOUSE
θ value	0.00228821 (rank : 306)	NC score	0.237067 (rank : 285)
Query Neighborhood Hits	997	Target Neighborhood Hits	189	Shared Neighborhood Hits	155
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

AN13C_MOUSE
θ value	0.00298849 (rank : 307)	NC score	0.503436 (rank : 231)
Query Neighborhood Hits	997	Target Neighborhood Hits	242	Shared Neighborhood Hits	232
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

ASB6_HUMAN
θ value	0.00298849 (rank : 308)	NC score	0.688293 (rank : 168)
Query Neighborhood Hits	997	Target Neighborhood Hits	256	Shared Neighborhood Hits	245
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ASB6_MOUSE
θ value	0.00298849 (rank : 309)	NC score	0.682823 (rank : 173)
Query Neighborhood Hits	997	Target Neighborhood Hits	264	Shared Neighborhood Hits	243
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

CENG2_HUMAN
θ value	0.00298849 (rank : 310)	NC score	0.338955 (rank : 271)
Query Neighborhood Hits	997	Target Neighborhood Hits	471	Shared Neighborhood Hits	263
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

DGKZ_HUMAN
θ value	0.00298849 (rank : 311)	NC score	0.368429 (rank : 265)
Query Neighborhood Hits	997	Target Neighborhood Hits	551	Shared Neighborhood Hits	221
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

LRRK1_HUMAN
θ value	0.00298849 (rank : 312)	NC score	0.105136 (rank : 408)
Query Neighborhood Hits	997	Target Neighborhood Hits	1237	Shared Neighborhood Hits	163
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

MAST1_MOUSE
θ value	0.00298849 (rank : 313)	NC score	0.036828 (rank : 1035)
Query Neighborhood Hits	997	Target Neighborhood Hits	1123	Shared Neighborhood Hits	149
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

ULK1_MOUSE
θ value	0.00298849 (rank : 314)	NC score	0.055168 (rank : 815)
Query Neighborhood Hits	997	Target Neighborhood Hits	1214	Shared Neighborhood Hits	226
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

ANR43_MOUSE
θ value	0.00390308 (rank : 315)	NC score	0.590241 (rank : 197)
Query Neighborhood Hits	997	Target Neighborhood Hits	214	Shared Neighborhood Hits	204
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

CCD96_HUMAN
θ value	0.00390308 (rank : 316)	NC score	0.049833 (rank : 939)
Query Neighborhood Hits	997	Target Neighborhood Hits	595	Shared Neighborhood Hits	95
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CDN2B_HUMAN
θ value	0.00390308 (rank : 317)	NC score	0.589217 (rank : 198)
Query Neighborhood Hits	997	Target Neighborhood Hits	196	Shared Neighborhood Hits	196
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

CENG1_MOUSE
θ value	0.00390308 (rank : 318)	NC score	0.354254 (rank : 266)
Query Neighborhood Hits	997	Target Neighborhood Hits	531	Shared Neighborhood Hits	307
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

MYO15_HUMAN
θ value	0.00390308 (rank : 319)	NC score	0.041674 (rank : 995)
Query Neighborhood Hits	997	Target Neighborhood Hits	671	Shared Neighborhood Hits	232
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

TCGAP_HUMAN
θ value	0.00390308 (rank : 320)	NC score	0.091127 (rank : 456)
Query Neighborhood Hits	997	Target Neighborhood Hits	872	Shared Neighborhood Hits	288
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

AN13C_HUMAN
θ value	0.00509761 (rank : 321)	NC score	0.512419 (rank : 228)
Query Neighborhood Hits	997	Target Neighborhood Hits	241	Shared Neighborhood Hits	234
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

CD2A1_HUMAN
θ value	0.00509761 (rank : 322)	NC score	0.607489 (rank : 192)
Query Neighborhood Hits	997	Target Neighborhood Hits	196	Shared Neighborhood Hits	193
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

EPHB6_MOUSE
θ value	0.00509761 (rank : 323)	NC score	0.114526 (rank : 366)
Query Neighborhood Hits	997	Target Neighborhood Hits	906	Shared Neighborhood Hits	105
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

NUD12_MOUSE
θ value	0.00509761 (rank : 324)	NC score	0.553421 (rank : 212)
Query Neighborhood Hits	997	Target Neighborhood Hits	243	Shared Neighborhood Hits	219
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

TRPV6_HUMAN
θ value	0.00509761 (rank : 325)	NC score	0.447656 (rank : 247)
Query Neighborhood Hits	997	Target Neighborhood Hits	262	Shared Neighborhood Hits	225
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

CEND3_HUMAN
θ value	0.00665767 (rank : 326)	NC score	0.102880 (rank : 415)
Query Neighborhood Hits	997	Target Neighborhood Hits	275	Shared Neighborhood Hits	122
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CENG2_MOUSE
θ value	0.00665767 (rank : 327)	NC score	0.336039 (rank : 273)
Query Neighborhood Hits	997	Target Neighborhood Hits	463	Shared Neighborhood Hits	260
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

DGKZ_MOUSE
θ value	0.00665767 (rank : 328)	NC score	0.351129 (rank : 267)
Query Neighborhood Hits	997	Target Neighborhood Hits	542	Shared Neighborhood Hits	208
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

K1802_HUMAN
θ value	0.00665767 (rank : 329)	NC score	0.092569 (rank : 451)
Query Neighborhood Hits	997	Target Neighborhood Hits	1378	Shared Neighborhood Hits	310
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

SPR1B_MOUSE
θ value	0.00665767 (rank : 330)	NC score	0.078765 (rank : 512)
Query Neighborhood Hits	997	Target Neighborhood Hits	395	Shared Neighborhood Hits	146
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

CDN2B_MOUSE
θ value	0.00869519 (rank : 331)	NC score	0.636058 (rank : 188)
Query Neighborhood Hits	997	Target Neighborhood Hits	201	Shared Neighborhood Hits	199
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

CENG1_HUMAN
θ value	0.00869519 (rank : 332)	NC score	0.350721 (rank : 269)
Query Neighborhood Hits	997	Target Neighborhood Hits	544	Shared Neighborhood Hits	307
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

FA47B_HUMAN
θ value	0.00869519 (rank : 333)	NC score	0.104673 (rank : 410)
Query Neighborhood Hits	997	Target Neighborhood Hits	431	Shared Neighborhood Hits	154
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

HIC1_HUMAN
θ value	0.00869519 (rank : 334)	NC score	-0.006459 (rank : 1328)
Query Neighborhood Hits	997	Target Neighborhood Hits	838	Shared Neighborhood Hits	66
SwissProt Accessions	Q14526	Gene names	HIC1, ZBTB29
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1) (Zinc finger and BTB domain-containing protein 29).

JADE2_MOUSE
θ value	0.00869519 (rank : 335)	NC score	0.050951 (rank : 910)
Query Neighborhood Hits	997	Target Neighborhood Hits	560	Shared Neighborhood Hits	180
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

NCOA6_MOUSE
θ value	0.00869519 (rank : 336)	NC score	0.140841 (rank : 325)
Query Neighborhood Hits	997	Target Neighborhood Hits	1076	Shared Neighborhood Hits	324
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

ANR43_HUMAN
θ value	0.0113563 (rank : 337)	NC score	0.591098 (rank : 196)
Query Neighborhood Hits	997	Target Neighborhood Hits	209	Shared Neighborhood Hits	202
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

BIN1_HUMAN
θ value	0.0113563 (rank : 338)	NC score	0.059660 (rank : 732)
Query Neighborhood Hits	997	Target Neighborhood Hits	335	Shared Neighborhood Hits	103
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

MUCDL_HUMAN
θ value	0.0113563 (rank : 339)	NC score	0.103019 (rank : 414)
Query Neighborhood Hits	997	Target Neighborhood Hits	777	Shared Neighborhood Hits	239
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

OGFR_MOUSE
θ value	0.0113563 (rank : 340)	NC score	0.099327 (rank : 423)
Query Neighborhood Hits	997	Target Neighborhood Hits	584	Shared Neighborhood Hits	171
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

SARM1_HUMAN
θ value	0.0113563 (rank : 341)	NC score	0.087097 (rank : 479)
Query Neighborhood Hits	997	Target Neighborhood Hits	58	Shared Neighborhood Hits	19
SwissProt Accessions	Q6SZW1, O60277, Q7LGG3, Q9NXY5	Gene names	SARM1, KIAA0524, SARM
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Sterile alpha and Armadillo repeat protein) (Tir-1 homolog).

T22D4_HUMAN
θ value	0.0113563 (rank : 342)	NC score	0.065454 (rank : 632)
Query Neighborhood Hits	997	Target Neighborhood Hits	403	Shared Neighborhood Hits	157
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

TRPV2_HUMAN
θ value	0.0113563 (rank : 343)	NC score	0.212091 (rank : 292)
Query Neighborhood Hits	997	Target Neighborhood Hits	130	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

ZIMP7_MOUSE
θ value	0.0113563 (rank : 344)	NC score	0.073806 (rank : 547)
Query Neighborhood Hits	997	Target Neighborhood Hits	566	Shared Neighborhood Hits	223
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

AHI1_HUMAN
θ value	0.0148317 (rank : 345)	NC score	0.038665 (rank : 1016)
Query Neighborhood Hits	997	Target Neighborhood Hits	537	Shared Neighborhood Hits	70
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

AMOL1_MOUSE
θ value	0.0148317 (rank : 346)	NC score	0.039708 (rank : 1007)
Query Neighborhood Hits	997	Target Neighborhood Hits	445	Shared Neighborhood Hits	65
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

C2TA_HUMAN
θ value	0.0148317 (rank : 347)	NC score	0.043191 (rank : 986)
Query Neighborhood Hits	997	Target Neighborhood Hits	190	Shared Neighborhood Hits	55
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

CTDP1_HUMAN
θ value	0.0148317 (rank : 348)	NC score	0.086712 (rank : 480)
Query Neighborhood Hits	997	Target Neighborhood Hits	416	Shared Neighborhood Hits	165
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

GNAS1_HUMAN
θ value	0.0148317 (rank : 349)	NC score	0.037815 (rank : 1024)
Query Neighborhood Hits	997	Target Neighborhood Hits	278	Shared Neighborhood Hits	110
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

PCLO_HUMAN
θ value	0.0148317 (rank : 350)	NC score	0.136022 (rank : 330)
Query Neighborhood Hits	997	Target Neighborhood Hits	2046	Shared Neighborhood Hits	441
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

WASP_MOUSE
θ value	0.0148317 (rank : 351)	NC score	0.109762 (rank : 391)
Query Neighborhood Hits	997	Target Neighborhood Hits	223	Shared Neighborhood Hits	127
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

HAIR_HUMAN
θ value	0.0193708 (rank : 352)	NC score	0.038733 (rank : 1015)
Query Neighborhood Hits	997	Target Neighborhood Hits	172	Shared Neighborhood Hits	52
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

IASPP_HUMAN
θ value	0.0193708 (rank : 353)	NC score	0.573541 (rank : 203)
Query Neighborhood Hits	997	Target Neighborhood Hits	688	Shared Neighborhood Hits	417
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

PRG4_HUMAN
θ value	0.0193708 (rank : 354)	NC score	0.158422 (rank : 314)
Query Neighborhood Hits	997	Target Neighborhood Hits	764	Shared Neighborhood Hits	260
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SAMD8_MOUSE
θ value	0.0193708 (rank : 355)	NC score	0.039351 (rank : 1010)
Query Neighborhood Hits	997	Target Neighborhood Hits	22	Shared Neighborhood Hits	9
SwissProt Accessions	Q9DA37	Gene names	Samd8
Domain Architecture
Description	Sphingomyelin synthase-related protein 1 (Sterile alpha motif domain- containing 8).

SAPS1_HUMAN
θ value	0.0193708 (rank : 356)	NC score	0.084673 (rank : 485)
Query Neighborhood Hits	997	Target Neighborhood Hits	704	Shared Neighborhood Hits	255
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SEPT9_HUMAN
θ value	0.0193708 (rank : 357)	NC score	0.052484 (rank : 863)
Query Neighborhood Hits	997	Target Neighborhood Hits	706	Shared Neighborhood Hits	199
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

WDR46_MOUSE
θ value	0.0193708 (rank : 358)	NC score	0.046182 (rank : 964)
Query Neighborhood Hits	997	Target Neighborhood Hits	243	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

WIRE_MOUSE
θ value	0.0193708 (rank : 359)	NC score	0.162371 (rank : 309)
Query Neighborhood Hits	997	Target Neighborhood Hits	310	Shared Neighborhood Hits	170
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

CENB1_HUMAN
θ value	0.0252991 (rank : 360)	NC score	0.523272 (rank : 223)
Query Neighborhood Hits	997	Target Neighborhood Hits	383	Shared Neighborhood Hits	270
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

DGKD_HUMAN
θ value	0.0252991 (rank : 361)	NC score	0.088331 (rank : 471)
Query Neighborhood Hits	997	Target Neighborhood Hits	231	Shared Neighborhood Hits	72
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

LRRK1_MOUSE
θ value	0.0252991 (rank : 362)	NC score	0.126993 (rank : 344)
Query Neighborhood Hits	997	Target Neighborhood Hits	1267	Shared Neighborhood Hits	186
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

LRSM1_MOUSE
θ value	0.0252991 (rank : 363)	NC score	0.044016 (rank : 980)
Query Neighborhood Hits	997	Target Neighborhood Hits	874	Shared Neighborhood Hits	65
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

NCOR2_MOUSE
θ value	0.0252991 (rank : 364)	NC score	0.077068 (rank : 521)
Query Neighborhood Hits	997	Target Neighborhood Hits	790	Shared Neighborhood Hits	184
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

PI5PA_HUMAN
θ value	0.0252991 (rank : 365)	NC score	0.109504 (rank : 392)
Query Neighborhood Hits	997	Target Neighborhood Hits	749	Shared Neighborhood Hits	289
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PRP2_MOUSE
θ value	0.0252991 (rank : 366)	NC score	0.197662 (rank : 296)
Query Neighborhood Hits	997	Target Neighborhood Hits	347	Shared Neighborhood Hits	180
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

ZN687_HUMAN
θ value	0.0252991 (rank : 367)	NC score	0.025471 (rank : 1126)
Query Neighborhood Hits	997	Target Neighborhood Hits	1244	Shared Neighborhood Hits	253
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

BCL9_HUMAN
θ value	0.0330416 (rank : 368)	NC score	0.130240 (rank : 338)
Query Neighborhood Hits	997	Target Neighborhood Hits	1008	Shared Neighborhood Hits	327
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CMTA2_HUMAN
θ value	0.0330416 (rank : 369)	NC score	0.191156 (rank : 298)
Query Neighborhood Hits	997	Target Neighborhood Hits	199	Shared Neighborhood Hits	130
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CMTA2_MOUSE
θ value	0.0330416 (rank : 370)	NC score	0.179591 (rank : 301)
Query Neighborhood Hits	997	Target Neighborhood Hits	216	Shared Neighborhood Hits	125
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

DGKH_HUMAN
θ value	0.0330416 (rank : 371)	NC score	0.073789 (rank : 548)
Query Neighborhood Hits	997	Target Neighborhood Hits	255	Shared Neighborhood Hits	67
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

EPHA3_HUMAN
θ value	0.0330416 (rank : 372)	NC score	0.096465 (rank : 436)
Query Neighborhood Hits	997	Target Neighborhood Hits	1005	Shared Neighborhood Hits	93
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

FYB_HUMAN
θ value	0.0330416 (rank : 373)	NC score	0.097025 (rank : 432)
Query Neighborhood Hits	997	Target Neighborhood Hits	379	Shared Neighborhood Hits	139
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

M3K11_HUMAN
θ value	0.0330416 (rank : 374)	NC score	0.075157 (rank : 538)
Query Neighborhood Hits	997	Target Neighborhood Hits	1136	Shared Neighborhood Hits	196
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

MEF2B_MOUSE
θ value	0.0330416 (rank : 375)	NC score	0.045418 (rank : 969)
Query Neighborhood Hits	997	Target Neighborhood Hits	218	Shared Neighborhood Hits	97
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

MILK1_MOUSE
θ value	0.0330416 (rank : 376)	NC score	0.087502 (rank : 476)
Query Neighborhood Hits	997	Target Neighborhood Hits	788	Shared Neighborhood Hits	264
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

PRR8_HUMAN
θ value	0.0330416 (rank : 377)	NC score	0.099966 (rank : 422)
Query Neighborhood Hits	997	Target Neighborhood Hits	217	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

CASL_MOUSE
θ value	0.0431538 (rank : 378)	NC score	0.060552 (rank : 710)
Query Neighborhood Hits	997	Target Neighborhood Hits	225	Shared Neighborhood Hits	69
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

CEND3_MOUSE
θ value	0.0431538 (rank : 379)	NC score	0.098225 (rank : 427)
Query Neighborhood Hits	997	Target Neighborhood Hits	228	Shared Neighborhood Hits	103
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CLPB_HUMAN
θ value	0.0431538 (rank : 380)	NC score	0.557843 (rank : 209)
Query Neighborhood Hits	997	Target Neighborhood Hits	265	Shared Neighborhood Hits	234
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

CLR59_HUMAN
θ value	0.0431538 (rank : 381)	NC score	0.305182 (rank : 280)
Query Neighborhood Hits	997	Target Neighborhood Hits	163	Shared Neighborhood Hits	143
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

FXL19_MOUSE
θ value	0.0431538 (rank : 382)	NC score	0.033442 (rank : 1063)
Query Neighborhood Hits	997	Target Neighborhood Hits	217	Shared Neighborhood Hits	77
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

GLSK_HUMAN
θ value	0.0431538 (rank : 383)	NC score	0.463760 (rank : 243)
Query Neighborhood Hits	997	Target Neighborhood Hits	204	Shared Neighborhood Hits	189
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

HEMGN_MOUSE
θ value	0.0431538 (rank : 384)	NC score	0.038392 (rank : 1019)
Query Neighborhood Hits	997	Target Neighborhood Hits	81	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ERZ0, Q3TAE6, Q80YT2, Q8CF29	Gene names	Hemgn, Ndr
Domain Architecture	No domain graphic available
Description	Hemogen (Hemopoietic gene protein) (Negative differentiation regulator protein) (mNDR).

LARP4_MOUSE
θ value	0.0431538 (rank : 385)	NC score	0.074867 (rank : 542)
Query Neighborhood Hits	997	Target Neighborhood Hits	260	Shared Neighborhood Hits	86
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

NUD12_HUMAN
θ value	0.0431538 (rank : 386)	NC score	0.516207 (rank : 226)
Query Neighborhood Hits	997	Target Neighborhood Hits	222	Shared Neighborhood Hits	198
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

PHLB1_HUMAN
θ value	0.0431538 (rank : 387)	NC score	0.068998 (rank : 588)
Query Neighborhood Hits	997	Target Neighborhood Hits	1038	Shared Neighborhood Hits	191
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PKN3_MOUSE
θ value	0.0431538 (rank : 388)	NC score	0.037220 (rank : 1029)
Query Neighborhood Hits	997	Target Neighborhood Hits	1009	Shared Neighborhood Hits	130
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

TRPV2_MOUSE
θ value	0.0431538 (rank : 389)	NC score	0.167923 (rank : 304)
Query Neighborhood Hits	997	Target Neighborhood Hits	111	Shared Neighborhood Hits	95
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

ZDHC5_MOUSE
θ value	0.0431538 (rank : 390)	NC score	0.051376 (rank : 893)
Query Neighborhood Hits	997	Target Neighborhood Hits	113	Shared Neighborhood Hits	34
SwissProt Accessions	Q8VDZ4, Q69ZB5, Q8R2X7	Gene names	Zdhhc5, Kiaa1748
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC5 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 5) (DHHC-5).

BCAR1_HUMAN
θ value	0.0563607 (rank : 391)	NC score	0.097176 (rank : 431)
Query Neighborhood Hits	997	Target Neighborhood Hits	554	Shared Neighborhood Hits	201
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BCL9_MOUSE
θ value	0.0563607 (rank : 392)	NC score	0.128880 (rank : 343)
Query Neighborhood Hits	997	Target Neighborhood Hits	770	Shared Neighborhood Hits	287
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CK024_HUMAN
θ value	0.0563607 (rank : 393)	NC score	0.118198 (rank : 359)
Query Neighborhood Hits	997	Target Neighborhood Hits	408	Shared Neighborhood Hits	161
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

ENAM_MOUSE
θ value	0.0563607 (rank : 394)	NC score	0.063306 (rank : 658)
Query Neighborhood Hits	997	Target Neighborhood Hits	229	Shared Neighborhood Hits	86
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

PRP1_HUMAN
θ value	0.0563607 (rank : 395)	NC score	0.196475 (rank : 297)
Query Neighborhood Hits	997	Target Neighborhood Hits	385	Shared Neighborhood Hits	193
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

SASH1_HUMAN
θ value	0.0563607 (rank : 396)	NC score	0.131138 (rank : 335)
Query Neighborhood Hits	997	Target Neighborhood Hits	292	Shared Neighborhood Hits	145
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

SHAN2_HUMAN
θ value	0.0563607 (rank : 397)	NC score	0.106781 (rank : 402)
Query Neighborhood Hits	997	Target Neighborhood Hits	346	Shared Neighborhood Hits	119
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SHAN2_MOUSE
θ value	0.0563607 (rank : 398)	NC score	0.111506 (rank : 376)
Query Neighborhood Hits	997	Target Neighborhood Hits	446	Shared Neighborhood Hits	148
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

TXND2_HUMAN
θ value	0.0563607 (rank : 399)	NC score	0.097291 (rank : 430)
Query Neighborhood Hits	997	Target Neighborhood Hits	793	Shared Neighborhood Hits	165
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

BSN_MOUSE
θ value	0.0736092 (rank : 400)	NC score	0.144885 (rank : 321)
Query Neighborhood Hits	997	Target Neighborhood Hits	2057	Shared Neighborhood Hits	472
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CIC_HUMAN
θ value	0.0736092 (rank : 401)	NC score	0.112685 (rank : 370)
Query Neighborhood Hits	997	Target Neighborhood Hits	992	Shared Neighborhood Hits	344
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

EPHA3_MOUSE
θ value	0.0736092 (rank : 402)	NC score	0.096287 (rank : 440)
Query Neighborhood Hits	997	Target Neighborhood Hits	1009	Shared Neighborhood Hits	92
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

GON4L_MOUSE
θ value	0.0736092 (rank : 403)	NC score	0.052994 (rank : 853)
Query Neighborhood Hits	997	Target Neighborhood Hits	455	Shared Neighborhood Hits	107
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

PRG4_MOUSE
θ value	0.0736092 (rank : 404)	NC score	0.136527 (rank : 329)
Query Neighborhood Hits	997	Target Neighborhood Hits	624	Shared Neighborhood Hits	201
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SLY_HUMAN
θ value	0.0736092 (rank : 405)	NC score	0.085207 (rank : 484)
Query Neighborhood Hits	997	Target Neighborhood Hits	81	Shared Neighborhood Hits	39
SwissProt Accessions	O75995	Gene names	SLY, CXorf9
Domain Architecture
Description	SH3 protein expressed in lymphocytes homolog.

SLY_MOUSE
θ value	0.0736092 (rank : 406)	NC score	0.087936 (rank : 473)
Query Neighborhood Hits	997	Target Neighborhood Hits	108	Shared Neighborhood Hits	42
SwissProt Accessions	Q8K352, Q3TBX0, Q9DBV2	Gene names	Sly
Domain Architecture
Description	SH3 protein expressed in lymphocytes.

USBP1_HUMAN
θ value	0.0736092 (rank : 407)	NC score	0.030355 (rank : 1081)
Query Neighborhood Hits	997	Target Neighborhood Hits	188	Shared Neighborhood Hits	27
SwissProt Accessions	Q8N6Y0, Q8NBX7, Q96KH3, Q9BYI8	Gene names	USHBP1, AIEBP, MCC2
Domain Architecture	No domain graphic available
Description	USH1C-binding protein 1 (Usher syndrome type-1C protein-binding protein 1) (MCC-2) (AIE-75 binding protein).

BAT2_MOUSE
θ value	0.0961366 (rank : 408)	NC score	0.129406 (rank : 341)
Query Neighborhood Hits	997	Target Neighborhood Hits	947	Shared Neighborhood Hits	337
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BCAR1_MOUSE
θ value	0.0961366 (rank : 409)	NC score	0.090141 (rank : 461)
Query Neighborhood Hits	997	Target Neighborhood Hits	438	Shared Neighborhood Hits	167
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CMTA1_HUMAN
θ value	0.0961366 (rank : 410)	NC score	0.213256 (rank : 291)
Query Neighborhood Hits	997	Target Neighborhood Hits	217	Shared Neighborhood Hits	126
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

DMRTD_HUMAN
θ value	0.0961366 (rank : 411)	NC score	0.065939 (rank : 622)
Query Neighborhood Hits	997	Target Neighborhood Hits	216	Shared Neighborhood Hits	99
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

K1683_HUMAN
θ value	0.0961366 (rank : 412)	NC score	0.079487 (rank : 507)
Query Neighborhood Hits	997	Target Neighborhood Hits	240	Shared Neighborhood Hits	88
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

NFAC1_HUMAN
θ value	0.0961366 (rank : 413)	NC score	0.053537 (rank : 838)
Query Neighborhood Hits	997	Target Neighborhood Hits	312	Shared Neighborhood Hits	131
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

SAMN1_MOUSE
θ value	0.0961366 (rank : 414)	NC score	0.087430 (rank : 478)
Query Neighborhood Hits	997	Target Neighborhood Hits	69	Shared Neighborhood Hits	37
SwissProt Accessions	P57725, Q8C6S2	Gene names	Samsn1
Domain Architecture
Description	SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1).

ZN174_HUMAN
θ value	0.0961366 (rank : 415)	NC score	-0.010407 (rank : 1334)
Query Neighborhood Hits	997	Target Neighborhood Hits	744	Shared Neighborhood Hits	44
SwissProt Accessions	Q15697, Q9BQ34	Gene names	ZNF174, ZSCAN8
Domain Architecture
Description	Zinc finger protein 174 (AW-1) (Zinc finger and SCAN domain-containing protein 8).

ARRD1_MOUSE
θ value	0.125558 (rank : 416)	NC score	0.032053 (rank : 1071)
Query Neighborhood Hits	997	Target Neighborhood Hits	90	Shared Neighborhood Hits	26
SwissProt Accessions	Q99KN1, Q3TDT6, Q8VEG7	Gene names	Arrdc1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

ATX7_HUMAN
θ value	0.125558 (rank : 417)	NC score	0.060491 (rank : 713)
Query Neighborhood Hits	997	Target Neighborhood Hits	351	Shared Neighborhood Hits	130
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

CO5A1_HUMAN
θ value	0.125558 (rank : 418)	NC score	0.065419 (rank : 634)
Query Neighborhood Hits	997	Target Neighborhood Hits	434	Shared Neighborhood Hits	169
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

CO5A1_MOUSE
θ value	0.125558 (rank : 419)	NC score	0.062778 (rank : 665)
Query Neighborhood Hits	997	Target Neighborhood Hits	419	Shared Neighborhood Hits	166
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

CS007_MOUSE
θ value	0.125558 (rank : 420)	NC score	0.096766 (rank : 434)
Query Neighborhood Hits	997	Target Neighborhood Hits	464	Shared Neighborhood Hits	168
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

FOG1_MOUSE
θ value	0.125558 (rank : 421)	NC score	0.027061 (rank : 1112)
Query Neighborhood Hits	997	Target Neighborhood Hits	1237	Shared Neighborhood Hits	246
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

JPH2_HUMAN
θ value	0.125558 (rank : 422)	NC score	0.067805 (rank : 599)
Query Neighborhood Hits	997	Target Neighborhood Hits	639	Shared Neighborhood Hits	238
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

MAP4_HUMAN
θ value	0.125558 (rank : 423)	NC score	0.080804 (rank : 504)
Query Neighborhood Hits	997	Target Neighborhood Hits	428	Shared Neighborhood Hits	140
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MEGF9_MOUSE
θ value	0.125558 (rank : 424)	NC score	0.072634 (rank : 557)
Query Neighborhood Hits	997	Target Neighborhood Hits	896	Shared Neighborhood Hits	226
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

PSL1_HUMAN
θ value	0.125558 (rank : 425)	NC score	0.074612 (rank : 543)
Query Neighborhood Hits	997	Target Neighborhood Hits	650	Shared Neighborhood Hits	226
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RFX1_HUMAN
θ value	0.125558 (rank : 426)	NC score	0.056036 (rank : 804)
Query Neighborhood Hits	997	Target Neighborhood Hits	256	Shared Neighborhood Hits	123
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

SAMN1_HUMAN
θ value	0.125558 (rank : 427)	NC score	0.087491 (rank : 477)
Query Neighborhood Hits	997	Target Neighborhood Hits	74	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NSI8, Q8NFF7, Q9C041	Gene names	SAMSN1, HACS1
Domain Architecture
Description	SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1) (SH3-SAM adaptor protein) (Hematopoietic adaptor containing SH3 and SAM domains 1).

SPEG_MOUSE
θ value	0.125558 (rank : 428)	NC score	0.051513 (rank : 887)
Query Neighborhood Hits	997	Target Neighborhood Hits	1959	Shared Neighborhood Hits	362
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SSBP4_HUMAN
θ value	0.125558 (rank : 429)	NC score	0.078877 (rank : 511)
Query Neighborhood Hits	997	Target Neighborhood Hits	753	Shared Neighborhood Hits	262
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

TRPC5_HUMAN
θ value	0.125558 (rank : 430)	NC score	0.069544 (rank : 582)
Query Neighborhood Hits	997	Target Neighborhood Hits	122	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

TRPC5_MOUSE
θ value	0.125558 (rank : 431)	NC score	0.070942 (rank : 575)
Query Neighborhood Hits	997	Target Neighborhood Hits	124	Shared Neighborhood Hits	72
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

TRPV5_HUMAN
θ value	0.125558 (rank : 432)	NC score	0.443646 (rank : 248)
Query Neighborhood Hits	997	Target Neighborhood Hits	261	Shared Neighborhood Hits	224
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

ASB14_HUMAN
θ value	0.163984 (rank : 433)	NC score	0.513011 (rank : 227)
Query Neighborhood Hits	997	Target Neighborhood Hits	187	Shared Neighborhood Hits	175
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ATN1_HUMAN
θ value	0.163984 (rank : 434)	NC score	0.140642 (rank : 326)
Query Neighborhood Hits	997	Target Neighborhood Hits	676	Shared Neighborhood Hits	216
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

ATX2L_HUMAN
θ value	0.163984 (rank : 435)	NC score	0.083963 (rank : 490)
Query Neighborhood Hits	997	Target Neighborhood Hits	443	Shared Neighborhood Hits	168
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

CBL_MOUSE
θ value	0.163984 (rank : 436)	NC score	0.033477 (rank : 1062)
Query Neighborhood Hits	997	Target Neighborhood Hits	426	Shared Neighborhood Hits	90
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

HRBL_MOUSE
θ value	0.163984 (rank : 437)	NC score	0.070965 (rank : 574)
Query Neighborhood Hits	997	Target Neighborhood Hits	269	Shared Neighborhood Hits	96
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

K0310_HUMAN
θ value	0.163984 (rank : 438)	NC score	0.084432 (rank : 486)
Query Neighborhood Hits	997	Target Neighborhood Hits	420	Shared Neighborhood Hits	165
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

K1543_HUMAN
θ value	0.163984 (rank : 439)	NC score	0.082578 (rank : 498)
Query Neighborhood Hits	997	Target Neighborhood Hits	435	Shared Neighborhood Hits	150
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

NR4A3_MOUSE
θ value	0.163984 (rank : 440)	NC score	0.011759 (rank : 1230)
Query Neighborhood Hits	997	Target Neighborhood Hits	127	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QZB6, Q9QZB5	Gene names	Nr4a3, Tec
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Orphan nuclear receptor TEC) (Translocated in extraskeletal chondrosarcoma).

OTU7A_MOUSE
θ value	0.163984 (rank : 441)	NC score	0.023546 (rank : 1135)
Query Neighborhood Hits	997	Target Neighborhood Hits	91	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R554	Gene names	Otud7a, Otud7
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7A (EC 3.-.-.-) (Zinc finger protein Cezanne 2).

PHLPP_MOUSE
θ value	0.163984 (rank : 442)	NC score	0.008387 (rank : 1253)
Query Neighborhood Hits	997	Target Neighborhood Hits	394	Shared Neighborhood Hits	46
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

STAC_HUMAN
θ value	0.163984 (rank : 443)	NC score	0.060668 (rank : 706)
Query Neighborhood Hits	997	Target Neighborhood Hits	276	Shared Neighborhood Hits	65
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

TXLNB_HUMAN
θ value	0.163984 (rank : 444)	NC score	0.047171 (rank : 958)
Query Neighborhood Hits	997	Target Neighborhood Hits	912	Shared Neighborhood Hits	154
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

VASP_HUMAN
θ value	0.163984 (rank : 445)	NC score	0.069229 (rank : 585)
Query Neighborhood Hits	997	Target Neighborhood Hits	201	Shared Neighborhood Hits	107
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

WBP11_MOUSE
θ value	0.163984 (rank : 446)	NC score	0.143504 (rank : 322)
Query Neighborhood Hits	997	Target Neighborhood Hits	362	Shared Neighborhood Hits	165
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

ANKY1_HUMAN
θ value	0.21417 (rank : 447)	NC score	0.519000 (rank : 225)
Query Neighborhood Hits	997	Target Neighborhood Hits	248	Shared Neighborhood Hits	209
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

ANKZ1_HUMAN
θ value	0.21417 (rank : 448)	NC score	0.318360 (rank : 276)
Query Neighborhood Hits	997	Target Neighborhood Hits	236	Shared Neighborhood Hits	162
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

ANKZ1_MOUSE
θ value	0.21417 (rank : 449)	NC score	0.336812 (rank : 272)
Query Neighborhood Hits	997	Target Neighborhood Hits	208	Shared Neighborhood Hits	155
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

BTBD7_MOUSE
θ value	0.21417 (rank : 450)	NC score	0.022617 (rank : 1142)
Query Neighborhood Hits	997	Target Neighborhood Hits	228	Shared Neighborhood Hits	37
SwissProt Accessions	Q8CFE5, Q80TC3, Q8BZY9	Gene names	Btbd7, Kiaa1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

CIC_MOUSE
θ value	0.21417 (rank : 451)	NC score	0.093418 (rank : 449)
Query Neighborhood Hits	997	Target Neighborhood Hits	742	Shared Neighborhood Hits	266
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

DOT1L_HUMAN
θ value	0.21417 (rank : 452)	NC score	0.076414 (rank : 526)
Query Neighborhood Hits	997	Target Neighborhood Hits	660	Shared Neighborhood Hits	176
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

GNAS1_MOUSE
θ value	0.21417 (rank : 453)	NC score	0.055602 (rank : 810)
Query Neighborhood Hits	997	Target Neighborhood Hits	651	Shared Neighborhood Hits	215
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

IKBL_HUMAN
θ value	0.21417 (rank : 454)	NC score	0.323145 (rank : 275)
Query Neighborhood Hits	997	Target Neighborhood Hits	168	Shared Neighborhood Hits	139
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

IKBL_MOUSE
θ value	0.21417 (rank : 455)	NC score	0.315475 (rank : 277)
Query Neighborhood Hits	997	Target Neighborhood Hits	196	Shared Neighborhood Hits	139
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

MBB1A_HUMAN
θ value	0.21417 (rank : 456)	NC score	0.077258 (rank : 518)
Query Neighborhood Hits	997	Target Neighborhood Hits	665	Shared Neighborhood Hits	196
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MINT_MOUSE
θ value	0.21417 (rank : 457)	NC score	0.081823 (rank : 501)
Query Neighborhood Hits	997	Target Neighborhood Hits	1514	Shared Neighborhood Hits	330
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MKL1_MOUSE
θ value	0.21417 (rank : 458)	NC score	0.072483 (rank : 558)
Query Neighborhood Hits	997	Target Neighborhood Hits	667	Shared Neighborhood Hits	228
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

NCOA5_MOUSE
θ value	0.21417 (rank : 459)	NC score	0.027013 (rank : 1113)
Query Neighborhood Hits	997	Target Neighborhood Hits	87	Shared Neighborhood Hits	27
SwissProt Accessions	Q91W39	Gene names	Ncoa5
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA).

SRBP1_MOUSE
θ value	0.21417 (rank : 460)	NC score	0.051522 (rank : 886)
Query Neighborhood Hits	997	Target Neighborhood Hits	384	Shared Neighborhood Hits	128
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

STAC_MOUSE
θ value	0.21417 (rank : 461)	NC score	0.060888 (rank : 700)
Query Neighborhood Hits	997	Target Neighborhood Hits	268	Shared Neighborhood Hits	67
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

TBC10_MOUSE
θ value	0.21417 (rank : 462)	NC score	0.019428 (rank : 1166)
Query Neighborhood Hits	997	Target Neighborhood Hits	94	Shared Neighborhood Hits	28
SwissProt Accessions	P58802	Gene names	Tbc1d10a, Epi64, Tbc1d10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

ALEX_HUMAN
θ value	0.279714 (rank : 463)	NC score	0.123987 (rank : 349)
Query Neighborhood Hits	997	Target Neighborhood Hits	361	Shared Neighborhood Hits	159
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

BSN_HUMAN
θ value	0.279714 (rank : 464)	NC score	0.133774 (rank : 332)
Query Neighborhood Hits	997	Target Neighborhood Hits	1537	Shared Neighborhood Hits	394
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CD248_MOUSE
θ value	0.279714 (rank : 465)	NC score	0.066180 (rank : 618)
Query Neighborhood Hits	997	Target Neighborhood Hits	578	Shared Neighborhood Hits	157
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

GON4L_HUMAN
θ value	0.279714 (rank : 466)	NC score	0.048997 (rank : 944)
Query Neighborhood Hits	997	Target Neighborhood Hits	555	Shared Neighborhood Hits	110
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

K1688_HUMAN
θ value	0.279714 (rank : 467)	NC score	0.031841 (rank : 1073)
Query Neighborhood Hits	997	Target Neighborhood Hits	217	Shared Neighborhood Hits	77
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

MAST1_HUMAN
θ value	0.279714 (rank : 468)	NC score	0.038001 (rank : 1023)
Query Neighborhood Hits	997	Target Neighborhood Hits	1146	Shared Neighborhood Hits	157
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MTR1L_HUMAN
θ value	0.279714 (rank : 469)	NC score	-0.006399 (rank : 1327)
Query Neighborhood Hits	997	Target Neighborhood Hits	1180	Shared Neighborhood Hits	97
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

NCOR2_HUMAN
θ value	0.279714 (rank : 470)	NC score	0.088757 (rank : 469)
Query Neighborhood Hits	997	Target Neighborhood Hits	870	Shared Neighborhood Hits	227
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NLGN3_MOUSE
θ value	0.279714 (rank : 471)	NC score	0.011958 (rank : 1229)
Query Neighborhood Hits	997	Target Neighborhood Hits	48	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BYM5, Q8BXR4	Gene names	Nlgn3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

PRB4S_HUMAN
θ value	0.279714 (rank : 472)	NC score	0.182255 (rank : 300)
Query Neighborhood Hits	997	Target Neighborhood Hits	330	Shared Neighborhood Hits	171
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

SEM6C_MOUSE
θ value	0.279714 (rank : 473)	NC score	0.023387 (rank : 1136)
Query Neighborhood Hits	997	Target Neighborhood Hits	352	Shared Neighborhood Hits	145
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SFPQ_MOUSE
θ value	0.279714 (rank : 474)	NC score	0.106432 (rank : 405)
Query Neighborhood Hits	997	Target Neighborhood Hits	958	Shared Neighborhood Hits	246
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SRRM1_HUMAN
θ value	0.279714 (rank : 475)	NC score	0.159416 (rank : 313)
Query Neighborhood Hits	997	Target Neighborhood Hits	690	Shared Neighborhood Hits	224
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

WBP11_HUMAN
θ value	0.279714 (rank : 476)	NC score	0.142919 (rank : 324)
Query Neighborhood Hits	997	Target Neighborhood Hits	354	Shared Neighborhood Hits	164
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

ADA12_MOUSE
θ value	0.365318 (rank : 477)	NC score	0.022316 (rank : 1144)
Query Neighborhood Hits	997	Target Neighborhood Hits	474	Shared Neighborhood Hits	140
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

BAG3_MOUSE
θ value	0.365318 (rank : 478)	NC score	0.095514 (rank : 442)
Query Neighborhood Hits	997	Target Neighborhood Hits	513	Shared Neighborhood Hits	209
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

BTBDC_HUMAN
θ value	0.365318 (rank : 479)	NC score	0.049076 (rank : 942)
Query Neighborhood Hits	997	Target Neighborhood Hits	248	Shared Neighborhood Hits	56
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

COBA1_HUMAN
θ value	0.365318 (rank : 480)	NC score	0.061272 (rank : 688)
Query Neighborhood Hits	997	Target Neighborhood Hits	491	Shared Neighborhood Hits	170
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COHA1_MOUSE
θ value	0.365318 (rank : 481)	NC score	0.066437 (rank : 612)
Query Neighborhood Hits	997	Target Neighborhood Hits	414	Shared Neighborhood Hits	159
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

DEN1A_MOUSE
θ value	0.365318 (rank : 482)	NC score	0.038413 (rank : 1018)
Query Neighborhood Hits	997	Target Neighborhood Hits	178	Shared Neighborhood Hits	74
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

K1543_MOUSE
θ value	0.365318 (rank : 483)	NC score	0.101185 (rank : 418)
Query Neighborhood Hits	997	Target Neighborhood Hits	497	Shared Neighborhood Hits	163
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

MAP1A_HUMAN
θ value	0.365318 (rank : 484)	NC score	0.065533 (rank : 630)
Query Neighborhood Hits	997	Target Neighborhood Hits	1626	Shared Neighborhood Hits	270
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

NCK2_HUMAN
θ value	0.365318 (rank : 485)	NC score	0.029416 (rank : 1087)
Query Neighborhood Hits	997	Target Neighborhood Hits	310	Shared Neighborhood Hits	64
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

OBSCN_HUMAN
θ value	0.365318 (rank : 486)	NC score	0.036311 (rank : 1040)
Query Neighborhood Hits	997	Target Neighborhood Hits	1931	Shared Neighborhood Hits	289
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

SAMD8_HUMAN
θ value	0.365318 (rank : 487)	NC score	0.029635 (rank : 1085)
Query Neighborhood Hits	997	Target Neighborhood Hits	22	Shared Neighborhood Hits	8
SwissProt Accessions	Q96LT4	Gene names	SAMD8
Domain Architecture
Description	Sphingomyelin synthase-related protein 1 (Sterile alpha motif domain- containing 8).

SPR1A_MOUSE
θ value	0.365318 (rank : 488)	NC score	0.068801 (rank : 590)
Query Neighborhood Hits	997	Target Neighborhood Hits	343	Shared Neighborhood Hits	124
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

STAM1_MOUSE
θ value	0.365318 (rank : 489)	NC score	0.052221 (rank : 870)
Query Neighborhood Hits	997	Target Neighborhood Hits	273	Shared Neighborhood Hits	71
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

WIRE_HUMAN
θ value	0.365318 (rank : 490)	NC score	0.159538 (rank : 312)
Query Neighborhood Hits	997	Target Neighborhood Hits	329	Shared Neighborhood Hits	176
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

YLPM1_MOUSE
θ value	0.365318 (rank : 491)	NC score	0.129062 (rank : 342)
Query Neighborhood Hits	997	Target Neighborhood Hits	505	Shared Neighborhood Hits	201
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ZF106_MOUSE
θ value	0.365318 (rank : 492)	NC score	0.015491 (rank : 1193)
Query Neighborhood Hits	997	Target Neighborhood Hits	472	Shared Neighborhood Hits	53
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

CO4A4_HUMAN
θ value	0.47712 (rank : 493)	NC score	0.064118 (rank : 645)
Query Neighborhood Hits	997	Target Neighborhood Hits	440	Shared Neighborhood Hits	161
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

CUTL1_MOUSE
θ value	0.47712 (rank : 494)	NC score	0.037230 (rank : 1028)
Query Neighborhood Hits	997	Target Neighborhood Hits	1620	Shared Neighborhood Hits	177
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

FOXN1_HUMAN
θ value	0.47712 (rank : 495)	NC score	0.026707 (rank : 1116)
Query Neighborhood Hits	997	Target Neighborhood Hits	377	Shared Neighborhood Hits	139
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

GAK11_HUMAN
θ value	0.47712 (rank : 496)	NC score	0.037186 (rank : 1031)
Query Neighborhood Hits	997	Target Neighborhood Hits	409	Shared Neighborhood Hits	138
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
θ value	0.47712 (rank : 497)	NC score	0.036800 (rank : 1037)
Query Neighborhood Hits	997	Target Neighborhood Hits	406	Shared Neighborhood Hits	137
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
θ value	0.47712 (rank : 498)	NC score	0.037593 (rank : 1025)
Query Neighborhood Hits	997	Target Neighborhood Hits	415	Shared Neighborhood Hits	142
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GSCR1_HUMAN
θ value	0.47712 (rank : 499)	NC score	0.166816 (rank : 306)
Query Neighborhood Hits	997	Target Neighborhood Hits	674	Shared Neighborhood Hits	279
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

HCLS1_HUMAN
θ value	0.47712 (rank : 500)	NC score	0.049517 (rank : 941)
Query Neighborhood Hits	997	Target Neighborhood Hits	358	Shared Neighborhood Hits	127
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

JIP3_HUMAN
θ value	0.47712 (rank : 501)	NC score	0.041159 (rank : 1001)
Query Neighborhood Hits	997	Target Neighborhood Hits	1039	Shared Neighborhood Hits	174
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

MARK2_MOUSE
θ value	0.47712 (rank : 502)	NC score	0.041537 (rank : 996)
Query Neighborhood Hits	997	Target Neighborhood Hits	1018	Shared Neighborhood Hits	129
SwissProt Accessions	Q05512, Q6PDR4, Q8BR95	Gene names	Mark2, Emk
Domain Architecture
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1).

MBB1A_MOUSE
θ value	0.47712 (rank : 503)	NC score	0.041340 (rank : 998)
Query Neighborhood Hits	997	Target Neighborhood Hits	233	Shared Neighborhood Hits	60
SwissProt Accessions	Q7TPV4, O35851, Q80Y66, Q8R4X2, Q99KP0	Gene names	Mybbp1a, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A (Myb-binding protein of 160 kDa).

OVOL2_HUMAN
θ value	0.47712 (rank : 504)	NC score	-0.010511 (rank : 1335)
Query Neighborhood Hits	997	Target Neighborhood Hits	715	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BRP0, Q5T8B4, Q9BX22, Q9HA54, Q9Y4M0	Gene names	OVOL2, ZNF339
Domain Architecture	No domain graphic available
Description	Transcription factor Ovo-like 2 (hOvo2) (Zinc finger protein 339).

PCOC1_HUMAN
θ value	0.47712 (rank : 505)	NC score	0.011281 (rank : 1234)
Query Neighborhood Hits	997	Target Neighborhood Hits	146	Shared Neighborhood Hits	34
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

SFTPA_MOUSE
θ value	0.47712 (rank : 506)	NC score	0.027496 (rank : 1107)
Query Neighborhood Hits	997	Target Neighborhood Hits	169	Shared Neighborhood Hits	49
SwissProt Accessions	P35242	Gene names	Sftpa1, Sftp-1, Sftp1, Sftpa
Domain Architecture
Description	Pulmonary surfactant-associated protein A precursor (SP-A) (PSP-A) (PSAP).

SOX17_MOUSE
θ value	0.47712 (rank : 507)	NC score	0.020944 (rank : 1155)
Query Neighborhood Hits	997	Target Neighborhood Hits	223	Shared Neighborhood Hits	73
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

SRRM1_MOUSE
θ value	0.47712 (rank : 508)	NC score	0.163299 (rank : 308)
Query Neighborhood Hits	997	Target Neighborhood Hits	966	Shared Neighborhood Hits	287
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

STAM1_HUMAN
θ value	0.47712 (rank : 509)	NC score	0.051080 (rank : 902)
Query Neighborhood Hits	997	Target Neighborhood Hits	271	Shared Neighborhood Hits	68
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

TPO_MOUSE
θ value	0.47712 (rank : 510)	NC score	0.046739 (rank : 960)
Query Neighborhood Hits	997	Target Neighborhood Hits	258	Shared Neighborhood Hits	91
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

TROAP_HUMAN
θ value	0.47712 (rank : 511)	NC score	0.079330 (rank : 508)
Query Neighborhood Hits	997	Target Neighborhood Hits	258	Shared Neighborhood Hits	102
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

TRPV1_HUMAN
θ value	0.47712 (rank : 512)	NC score	0.214821 (rank : 290)
Query Neighborhood Hits	997	Target Neighborhood Hits	184	Shared Neighborhood Hits	147
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

WNK2_HUMAN
θ value	0.47712 (rank : 513)	NC score	0.076557 (rank : 525)
Query Neighborhood Hits	997	Target Neighborhood Hits	1407	Shared Neighborhood Hits	309
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ARMX2_MOUSE
θ value	0.62314 (rank : 514)	NC score	0.055604 (rank : 809)
Query Neighborhood Hits	997	Target Neighborhood Hits	349	Shared Neighborhood Hits	136
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

CD2_HUMAN
θ value	0.62314 (rank : 515)	NC score	0.075243 (rank : 536)
Query Neighborhood Hits	997	Target Neighborhood Hits	504	Shared Neighborhood Hits	171
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CO4A6_HUMAN
θ value	0.62314 (rank : 516)	NC score	0.046357 (rank : 963)
Query Neighborhood Hits	997	Target Neighborhood Hits	318	Shared Neighborhood Hits	113
SwissProt Accessions	Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4	Gene names	COL4A6
Domain Architecture
Description	Collagen alpha-6(IV) chain precursor.

COBA1_MOUSE
θ value	0.62314 (rank : 517)	NC score	0.059745 (rank : 729)
Query Neighborhood Hits	997	Target Neighborhood Hits	487	Shared Neighborhood Hits	171
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COT2_HUMAN
θ value	0.62314 (rank : 518)	NC score	0.004378 (rank : 1293)
Query Neighborhood Hits	997	Target Neighborhood Hits	135	Shared Neighborhood Hits	26
SwissProt Accessions	P24468, Q03754	Gene names	NR2F2, ARP1, TFCOUP2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

COT2_MOUSE
θ value	0.62314 (rank : 519)	NC score	0.004378 (rank : 1294)
Query Neighborhood Hits	997	Target Neighborhood Hits	135	Shared Neighborhood Hits	26
SwissProt Accessions	P43135	Gene names	Nr2f2, Aporp1, Arp-1, Arp1, Tfcoup2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

GAK5_HUMAN
θ value	0.62314 (rank : 520)	NC score	0.037489 (rank : 1027)
Query Neighborhood Hits	997	Target Neighborhood Hits	429	Shared Neighborhood Hits	143
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK6_HUMAN
θ value	0.62314 (rank : 521)	NC score	0.037068 (rank : 1032)
Query Neighborhood Hits	997	Target Neighborhood Hits	392	Shared Neighborhood Hits	140
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

HXB3_HUMAN
θ value	0.62314 (rank : 522)	NC score	0.005676 (rank : 1286)
Query Neighborhood Hits	997	Target Neighborhood Hits	559	Shared Neighborhood Hits	113
SwissProt Accessions	P14651, O95615, P17484	Gene names	HOXB3, HOX2G
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2G) (Hox-2.7).

MARCO_HUMAN
θ value	0.62314 (rank : 523)	NC score	0.030328 (rank : 1082)
Query Neighborhood Hits	997	Target Neighborhood Hits	199	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UEW3, Q9Y5S3	Gene names	MARCO, SCARA2
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure) (Scavenger receptor class A member 2).

MMP15_MOUSE
θ value	0.62314 (rank : 524)	NC score	0.006976 (rank : 1271)
Query Neighborhood Hits	997	Target Neighborhood Hits	102	Shared Neighborhood Hits	38
SwissProt Accessions	O54732	Gene names	Mmp15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP).

NLGN3_HUMAN
θ value	0.62314 (rank : 525)	NC score	0.011136 (rank : 1236)
Query Neighborhood Hits	997	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZ94, Q8NCD0, Q9NZ95, Q9NZ96, Q9NZ97, Q9P248	Gene names	NLGN3, KIAA1480, NL3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

PDC6I_MOUSE
θ value	0.62314 (rank : 526)	NC score	0.064121 (rank : 644)
Query Neighborhood Hits	997	Target Neighborhood Hits	275	Shared Neighborhood Hits	106
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

PDXL2_HUMAN
θ value	0.62314 (rank : 527)	NC score	0.030493 (rank : 1079)
Query Neighborhood Hits	997	Target Neighborhood Hits	75	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZ53, Q6UVY4, Q8WUV6	Gene names	PODXL2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

PLXB1_MOUSE
θ value	0.62314 (rank : 528)	NC score	0.018697 (rank : 1174)
Query Neighborhood Hits	997	Target Neighborhood Hits	259	Shared Neighborhood Hits	87
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

PRB3_HUMAN
θ value	0.62314 (rank : 529)	NC score	0.172956 (rank : 303)
Query Neighborhood Hits	997	Target Neighborhood Hits	318	Shared Neighborhood Hits	161
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

SIX5_MOUSE
θ value	0.62314 (rank : 530)	NC score	0.022957 (rank : 1141)
Query Neighborhood Hits	997	Target Neighborhood Hits	354	Shared Neighborhood Hits	62
SwissProt Accessions	P70178	Gene names	Six5, Dmahp
Domain Architecture
Description	Homeobox protein SIX5 (DM locus-associated homeodomain protein homolog).

SOX13_MOUSE
θ value	0.62314 (rank : 531)	NC score	0.037549 (rank : 1026)
Query Neighborhood Hits	997	Target Neighborhood Hits	495	Shared Neighborhood Hits	147
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

SRCA_HUMAN
θ value	0.62314 (rank : 532)	NC score	0.040020 (rank : 1004)
Query Neighborhood Hits	997	Target Neighborhood Hits	380	Shared Neighborhood Hits	80
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

TBC10_HUMAN
θ value	0.62314 (rank : 533)	NC score	0.018154 (rank : 1178)
Query Neighborhood Hits	997	Target Neighborhood Hits	64	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BXI6, O76053, Q543A2	Gene names	TBC1D10A, EPI64, TBC1D10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

ATX2L_MOUSE
θ value	0.813845 (rank : 534)	NC score	0.070761 (rank : 577)
Query Neighborhood Hits	997	Target Neighborhood Hits	401	Shared Neighborhood Hits	146
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

CDN1C_HUMAN
θ value	0.813845 (rank : 535)	NC score	0.096777 (rank : 433)
Query Neighborhood Hits	997	Target Neighborhood Hits	168	Shared Neighborhood Hits	95
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CRKL_HUMAN
θ value	0.813845 (rank : 536)	NC score	0.037035 (rank : 1033)
Query Neighborhood Hits	997	Target Neighborhood Hits	313	Shared Neighborhood Hits	67
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

CRKL_MOUSE
θ value	0.813845 (rank : 537)	NC score	0.036452 (rank : 1039)
Query Neighborhood Hits	997	Target Neighborhood Hits	307	Shared Neighborhood Hits	62
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

DAB2_MOUSE
θ value	0.813845 (rank : 538)	NC score	0.048239 (rank : 952)
Query Neighborhood Hits	997	Target Neighborhood Hits	163	Shared Neighborhood Hits	59
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

DYN1_HUMAN
θ value	0.813845 (rank : 539)	NC score	0.033311 (rank : 1065)
Query Neighborhood Hits	997	Target Neighborhood Hits	216	Shared Neighborhood Hits	109
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

EFS_MOUSE
θ value	0.813845 (rank : 540)	NC score	0.066027 (rank : 621)
Query Neighborhood Hits	997	Target Neighborhood Hits	389	Shared Neighborhood Hits	133
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

FA8A1_HUMAN
θ value	0.813845 (rank : 541)	NC score	0.033584 (rank : 1060)
Query Neighborhood Hits	997	Target Neighborhood Hits	53	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UBU6	Gene names	FAM8A1, AHCP
Domain Architecture	No domain graphic available
Description	Protein FAM8A1 (Autosomal highly conserved protein).

FMNL_HUMAN
θ value	0.813845 (rank : 542)	NC score	0.096423 (rank : 439)
Query Neighborhood Hits	997	Target Neighborhood Hits	529	Shared Neighborhood Hits	182
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

FOXL2_MOUSE
θ value	0.813845 (rank : 543)	NC score	0.013022 (rank : 1219)
Query Neighborhood Hits	997	Target Neighborhood Hits	151	Shared Neighborhood Hits	50
SwissProt Accessions	O88470, Q8K3X9	Gene names	Foxl2, Pfrk
Domain Architecture	No domain graphic available
Description	Forkhead box protein L2 (Pituitary forkhead factor) (P-Frk).

LRSM1_HUMAN
θ value	0.813845 (rank : 544)	NC score	0.045352 (rank : 970)
Query Neighborhood Hits	997	Target Neighborhood Hits	1078	Shared Neighborhood Hits	92
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

MYO15_MOUSE
θ value	0.813845 (rank : 545)	NC score	0.029386 (rank : 1088)
Query Neighborhood Hits	997	Target Neighborhood Hits	467	Shared Neighborhood Hits	161
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

SFTA2_HUMAN
θ value	0.813845 (rank : 546)	NC score	0.026262 (rank : 1121)
Query Neighborhood Hits	997	Target Neighborhood Hits	169	Shared Neighborhood Hits	50
SwissProt Accessions	Q8IWL1, P07714, Q5RIR8, Q5RIR9	Gene names	SFTPA2, PSAP, SFTP1, SFTPA
Domain Architecture	No domain graphic available
Description	Pulmonary surfactant-associated protein A2 precursor (SP-A2) (SP-A) (PSP-A) (PSPA) (Alveolar proteinosis protein) (35 kDa pulmonary surfactant-associated protein).

TNR3_HUMAN
θ value	0.813845 (rank : 547)	NC score	0.014954 (rank : 1201)
Query Neighborhood Hits	997	Target Neighborhood Hits	145	Shared Neighborhood Hits	28
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TRPC4_HUMAN
θ value	0.813845 (rank : 548)	NC score	0.064793 (rank : 639)
Query Neighborhood Hits	997	Target Neighborhood Hits	140	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
θ value	0.813845 (rank : 549)	NC score	0.064911 (rank : 638)
Query Neighborhood Hits	997	Target Neighborhood Hits	141	Shared Neighborhood Hits	76
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

ZDHC5_HUMAN
θ value	0.813845 (rank : 550)	NC score	0.043651 (rank : 983)
Query Neighborhood Hits	997	Target Neighborhood Hits	106	Shared Neighborhood Hits	28
SwissProt Accessions	Q9C0B5, Q6ZMF0, Q8TAK8, Q9H923, Q9UFI7	Gene names	ZDHHC5, KIAA1748, ZNF375
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC5 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 5) (DHHC-5) (Zinc finger protein 375).

ZN385_HUMAN
θ value	0.813845 (rank : 551)	NC score	0.084101 (rank : 488)
Query Neighborhood Hits	997	Target Neighborhood Hits	614	Shared Neighborhood Hits	206
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

CF015_HUMAN
θ value	1.06291 (rank : 552)	NC score	0.028547 (rank : 1097)
Query Neighborhood Hits	997	Target Neighborhood Hits	60	Shared Neighborhood Hits	24
SwissProt Accessions	Q6UXA7, Q5SQ81, Q86Z05, Q9UIG3	Gene names	C6orf15, STG
Domain Architecture	No domain graphic available
Description	Protein C6orf15 precursor (Protein STG).

CO3A1_HUMAN
θ value	1.06291 (rank : 553)	NC score	0.073539 (rank : 550)
Query Neighborhood Hits	997	Target Neighborhood Hits	452	Shared Neighborhood Hits	175
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO3A1_MOUSE
θ value	1.06291 (rank : 554)	NC score	0.073520 (rank : 552)
Query Neighborhood Hits	997	Target Neighborhood Hits	466	Shared Neighborhood Hits	174
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO4A1_MOUSE
θ value	1.06291 (rank : 555)	NC score	0.057659 (rank : 778)
Query Neighborhood Hits	997	Target Neighborhood Hits	450	Shared Neighborhood Hits	173
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

CO9A3_HUMAN
θ value	1.06291 (rank : 556)	NC score	0.050632 (rank : 918)
Query Neighborhood Hits	997	Target Neighborhood Hits	361	Shared Neighborhood Hits	130
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

COIA1_MOUSE
θ value	1.06291 (rank : 557)	NC score	0.056348 (rank : 800)
Query Neighborhood Hits	997	Target Neighborhood Hits	481	Shared Neighborhood Hits	164
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

DIDO1_HUMAN
θ value	1.06291 (rank : 558)	NC score	0.089803 (rank : 465)
Query Neighborhood Hits	997	Target Neighborhood Hits	960	Shared Neighborhood Hits	261
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

GGA3_HUMAN
θ value	1.06291 (rank : 559)	NC score	0.020934 (rank : 1156)
Query Neighborhood Hits	997	Target Neighborhood Hits	127	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NZ52, Q15017, Q6IS16, Q9UJY3	Gene names	GGA3, KIAA0154
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

HDAC9_HUMAN
θ value	1.06291 (rank : 560)	NC score	0.015265 (rank : 1196)
Query Neighborhood Hits	997	Target Neighborhood Hits	201	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UKV0, O94845, O95028	Gene names	HDAC9, HDAC7, HDAC7B, KIAA0744
Domain Architecture
Description	Histone deacetylase 9 (HD9) (HD7B) (HD7).

HDAC9_MOUSE
θ value	1.06291 (rank : 561)	NC score	0.022246 (rank : 1145)
Query Neighborhood Hits	997	Target Neighborhood Hits	186	Shared Neighborhood Hits	22
SwissProt Accessions	Q99N13, Q9EPT2	Gene names	Hdac9, Hdac7b, Hdrp, Mitr
Domain Architecture	No domain graphic available
Description	Histone deacetylase 9 (HD9) (HD7B) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR).

HXA3_MOUSE
θ value	1.06291 (rank : 562)	NC score	0.021127 (rank : 1152)
Query Neighborhood Hits	997	Target Neighborhood Hits	558	Shared Neighborhood Hits	133
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

IWS1_MOUSE
θ value	1.06291 (rank : 563)	NC score	0.074899 (rank : 541)
Query Neighborhood Hits	997	Target Neighborhood Hits	1258	Shared Neighborhood Hits	212
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LAMA5_HUMAN
θ value	1.06291 (rank : 564)	NC score	0.042738 (rank : 991)
Query Neighborhood Hits	997	Target Neighborhood Hits	976	Shared Neighborhood Hits	118
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LPP_HUMAN
θ value	1.06291 (rank : 565)	NC score	0.050888 (rank : 912)
Query Neighborhood Hits	997	Target Neighborhood Hits	775	Shared Neighborhood Hits	221
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

LTB1L_HUMAN
θ value	1.06291 (rank : 566)	NC score	0.049051 (rank : 943)
Query Neighborhood Hits	997	Target Neighborhood Hits	553	Shared Neighborhood Hits	78
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	1.06291 (rank : 567)	NC score	0.047843 (rank : 955)
Query Neighborhood Hits	997	Target Neighborhood Hits	502	Shared Neighborhood Hits	65
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MAGD4_HUMAN
θ value	1.06291 (rank : 568)	NC score	0.033266 (rank : 1066)
Query Neighborhood Hits	997	Target Neighborhood Hits	338	Shared Neighborhood Hits	110
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

MISS_MOUSE
θ value	1.06291 (rank : 569)	NC score	0.097699 (rank : 428)
Query Neighborhood Hits	997	Target Neighborhood Hits	444	Shared Neighborhood Hits	188
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

PCDH7_HUMAN
θ value	1.06291 (rank : 570)	NC score	-0.005257 (rank : 1325)
Query Neighborhood Hits	997	Target Neighborhood Hits	175	Shared Neighborhood Hits	9
SwissProt Accessions	O60245, O60246, O60247	Gene names	PCDH7, BHPCDH
Domain Architecture
Description	Protocadherin-7 precursor (Brain-heart protocadherin) (BH-Pcdh).

PGCB_HUMAN
θ value	1.06291 (rank : 571)	NC score	0.030886 (rank : 1077)
Query Neighborhood Hits	997	Target Neighborhood Hits	478	Shared Neighborhood Hits	79
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

PO6F2_HUMAN
θ value	1.06291 (rank : 572)	NC score	0.035616 (rank : 1047)
Query Neighborhood Hits	997	Target Neighborhood Hits	618	Shared Neighborhood Hits	133
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

PRAX_MOUSE
θ value	1.06291 (rank : 573)	NC score	0.044269 (rank : 978)
Query Neighborhood Hits	997	Target Neighborhood Hits	199	Shared Neighborhood Hits	76
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

RAI1_HUMAN
θ value	1.06291 (rank : 574)	NC score	0.046515 (rank : 962)
Query Neighborhood Hits	997	Target Neighborhood Hits	360	Shared Neighborhood Hits	118
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RARG1_MOUSE
θ value	1.06291 (rank : 575)	NC score	0.004075 (rank : 1298)
Query Neighborhood Hits	997	Target Neighborhood Hits	113	Shared Neighborhood Hits	11
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

RARG2_MOUSE
θ value	1.06291 (rank : 576)	NC score	0.004060 (rank : 1299)
Query Neighborhood Hits	997	Target Neighborhood Hits	114	Shared Neighborhood Hits	11
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

RIMB1_HUMAN
θ value	1.06291 (rank : 577)	NC score	0.059829 (rank : 727)
Query Neighborhood Hits	997	Target Neighborhood Hits	1479	Shared Neighborhood Hits	250
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SPT5H_HUMAN
θ value	1.06291 (rank : 578)	NC score	0.069296 (rank : 584)
Query Neighborhood Hits	997	Target Neighborhood Hits	436	Shared Neighborhood Hits	148
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	1.06291 (rank : 579)	NC score	0.069044 (rank : 586)
Query Neighborhood Hits	997	Target Neighborhood Hits	437	Shared Neighborhood Hits	147
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

SYN1_MOUSE
θ value	1.06291 (rank : 580)	NC score	0.104288 (rank : 411)
Query Neighborhood Hits	997	Target Neighborhood Hits	363	Shared Neighborhood Hits	180
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

TS13_MOUSE
θ value	1.06291 (rank : 581)	NC score	0.048677 (rank : 949)
Query Neighborhood Hits	997	Target Neighborhood Hits	191	Shared Neighborhood Hits	75
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

ZN341_HUMAN
θ value	1.06291 (rank : 582)	NC score	-0.007465 (rank : 1330)
Query Neighborhood Hits	997	Target Neighborhood Hits	803	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BYN7, Q5JXM8, Q96ST5	Gene names	ZNF341
Domain Architecture	No domain graphic available
Description	Zinc finger protein 341.

ARHG6_MOUSE
θ value	1.38821 (rank : 583)	NC score	0.038541 (rank : 1017)
Query Neighborhood Hits	997	Target Neighborhood Hits	394	Shared Neighborhood Hits	71
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

BAZ2A_MOUSE
θ value	1.38821 (rank : 584)	NC score	0.053301 (rank : 845)
Query Neighborhood Hits	997	Target Neighborhood Hits	744	Shared Neighborhood Hits	184
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BRE1B_HUMAN
θ value	1.38821 (rank : 585)	NC score	0.028079 (rank : 1105)
Query Neighborhood Hits	997	Target Neighborhood Hits	1040	Shared Neighborhood Hits	90
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

CABIN_HUMAN
θ value	1.38821 (rank : 586)	NC score	0.090376 (rank : 459)
Query Neighborhood Hits	997	Target Neighborhood Hits	490	Shared Neighborhood Hits	184
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CASL_HUMAN
θ value	1.38821 (rank : 587)	NC score	0.050277 (rank : 925)
Query Neighborhood Hits	997	Target Neighborhood Hits	259	Shared Neighborhood Hits	74
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

CBL_HUMAN
θ value	1.38821 (rank : 588)	NC score	0.028299 (rank : 1102)
Query Neighborhood Hits	997	Target Neighborhood Hits	353	Shared Neighborhood Hits	68
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CO5A2_HUMAN
θ value	1.38821 (rank : 589)	NC score	0.073569 (rank : 549)
Query Neighborhood Hits	997	Target Neighborhood Hits	760	Shared Neighborhood Hits	238
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

CPSF6_HUMAN
θ value	1.38821 (rank : 590)	NC score	0.118438 (rank : 357)
Query Neighborhood Hits	997	Target Neighborhood Hits	359	Shared Neighborhood Hits	160
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	1.38821 (rank : 591)	NC score	0.119611 (rank : 355)
Query Neighborhood Hits	997	Target Neighborhood Hits	356	Shared Neighborhood Hits	160
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CT032_HUMAN
θ value	1.38821 (rank : 592)	NC score	0.066365 (rank : 614)
Query Neighborhood Hits	997	Target Neighborhood Hits	235	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

DYN1_MOUSE
θ value	1.38821 (rank : 593)	NC score	0.023067 (rank : 1138)
Query Neighborhood Hits	997	Target Neighborhood Hits	168	Shared Neighborhood Hits	73
SwissProt Accessions	P39053, Q61358, Q61359, Q61360, Q8JZZ4, Q9CSY7, Q9QXX1	Gene names	Dnm1, Dnm
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

ECM1_HUMAN
θ value	1.38821 (rank : 594)	NC score	0.036808 (rank : 1036)
Query Neighborhood Hits	997	Target Neighborhood Hits	182	Shared Neighborhood Hits	79
SwissProt Accessions	Q16610	Gene names	ECM1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

EP400_MOUSE
θ value	1.38821 (rank : 595)	NC score	0.048786 (rank : 947)
Query Neighborhood Hits	997	Target Neighborhood Hits	592	Shared Neighborhood Hits	178
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

ETV3_HUMAN
θ value	1.38821 (rank : 596)	NC score	0.021543 (rank : 1150)
Query Neighborhood Hits	997	Target Neighborhood Hits	312	Shared Neighborhood Hits	80
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

GAK12_HUMAN
θ value	1.38821 (rank : 597)	NC score	0.034872 (rank : 1054)
Query Neighborhood Hits	997	Target Neighborhood Hits	374	Shared Neighborhood Hits	124
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

HASP_MOUSE
θ value	1.38821 (rank : 598)	NC score	0.014691 (rank : 1205)
Query Neighborhood Hits	997	Target Neighborhood Hits	50	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z0R0, Q99MU9, Q9JJJ4	Gene names	Gsg2
Domain Architecture
Description	Serine/threonine-protein kinase Haspin (EC 2.7.11.1) (Haploid germ cell-specific nuclear protein kinase) (Germ cell-specific gene 2 protein).

MMTA2_HUMAN
θ value	1.38821 (rank : 599)	NC score	0.018691 (rank : 1175)
Query Neighborhood Hits	997	Target Neighborhood Hits	40	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BU76, Q6P5Y0, Q6ZTZ6, Q6ZWA6, Q8IZH3	Gene names	MMTAG2, C1orf35
Domain Architecture	No domain graphic available
Description	Multiple myeloma tumor-associated protein 2 (hMMTAG2).

MNT_HUMAN
θ value	1.38821 (rank : 600)	NC score	0.075677 (rank : 530)
Query Neighborhood Hits	997	Target Neighborhood Hits	496	Shared Neighborhood Hits	168
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

PER2_MOUSE
θ value	1.38821 (rank : 601)	NC score	0.024028 (rank : 1132)
Query Neighborhood Hits	997	Target Neighborhood Hits	325	Shared Neighborhood Hits	96
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

PITM1_HUMAN
θ value	1.38821 (rank : 602)	NC score	0.008711 (rank : 1251)
Query Neighborhood Hits	997	Target Neighborhood Hits	129	Shared Neighborhood Hits	40
SwissProt Accessions	O00562, Q6T7X3, Q8TBN3, Q9BZ73	Gene names	PITPNM1, DRES9, NIR2, PITPNM
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 1 (Phosphatidylinositol transfer protein, membrane-associated 1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) (Drosophila retinal degeneration B homolog).

PTN14_HUMAN
θ value	1.38821 (rank : 603)	NC score	0.003069 (rank : 1306)
Query Neighborhood Hits	997	Target Neighborhood Hits	163	Shared Neighborhood Hits	15
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTN14_MOUSE
θ value	1.38821 (rank : 604)	NC score	0.003306 (rank : 1304)
Query Neighborhood Hits	997	Target Neighborhood Hits	142	Shared Neighborhood Hits	12
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

RAPH1_HUMAN
θ value	1.38821 (rank : 605)	NC score	0.129545 (rank : 340)
Query Neighborhood Hits	997	Target Neighborhood Hits	593	Shared Neighborhood Hits	261
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RBBP5_HUMAN
θ value	1.38821 (rank : 606)	NC score	0.006502 (rank : 1276)
Query Neighborhood Hits	997	Target Neighborhood Hits	372	Shared Neighborhood Hits	26
SwissProt Accessions	Q15291	Gene names	RBBP5, RBQ3
Domain Architecture
Description	Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3).

SMCA4_HUMAN
θ value	1.38821 (rank : 607)	NC score	0.039222 (rank : 1012)
Query Neighborhood Hits	997	Target Neighborhood Hits	597	Shared Neighborhood Hits	173
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

ZIMP7_HUMAN
θ value	1.38821 (rank : 608)	NC score	0.043058 (rank : 988)
Query Neighborhood Hits	997	Target Neighborhood Hits	290	Shared Neighborhood Hits	120
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ZN746_HUMAN
θ value	1.38821 (rank : 609)	NC score	-0.011392 (rank : 1337)
Query Neighborhood Hits	997	Target Neighborhood Hits	745	Shared Neighborhood Hits	50
SwissProt Accessions	Q6NUN9	Gene names	ZNF746
Domain Architecture	No domain graphic available
Description	Zinc finger protein 746.

ZN750_MOUSE
θ value	1.38821 (rank : 610)	NC score	0.048919 (rank : 945)
Query Neighborhood Hits	997	Target Neighborhood Hits	346	Shared Neighborhood Hits	101
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

CAC1H_HUMAN
θ value	1.81305 (rank : 611)	NC score	0.012545 (rank : 1224)
Query Neighborhood Hits	997	Target Neighborhood Hits	307	Shared Neighborhood Hits	81
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CD2AP_HUMAN
θ value	1.81305 (rank : 612)	NC score	0.051828 (rank : 882)
Query Neighborhood Hits	997	Target Neighborhood Hits	315	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

CDKL2_MOUSE
θ value	1.81305 (rank : 613)	NC score	0.027220 (rank : 1110)
Query Neighborhood Hits	997	Target Neighborhood Hits	854	Shared Neighborhood Hits	74
SwissProt Accessions	Q9QUK0, Q3UL60, Q3V3X7, Q9QYI1, Q9QYI2	Gene names	Cdkl2, Kkiamre, Kkm
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Serine/threonine- protein kinase KKIAMRE).

CO1A2_MOUSE
θ value	1.81305 (rank : 614)	NC score	0.057569 (rank : 780)
Query Neighborhood Hits	997	Target Neighborhood Hits	388	Shared Neighborhood Hits	143
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO4A5_HUMAN
θ value	1.81305 (rank : 615)	NC score	0.072073 (rank : 562)
Query Neighborhood Hits	997	Target Neighborhood Hits	383	Shared Neighborhood Hits	158
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

CO9A1_HUMAN
θ value	1.81305 (rank : 616)	NC score	0.051025 (rank : 908)
Query Neighborhood Hits	997	Target Neighborhood Hits	420	Shared Neighborhood Hits	141
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

DOCK4_HUMAN
θ value	1.81305 (rank : 617)	NC score	0.023944 (rank : 1134)
Query Neighborhood Hits	997	Target Neighborhood Hits	237	Shared Neighborhood Hits	83
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

FMN2_HUMAN
θ value	1.81305 (rank : 618)	NC score	0.093831 (rank : 446)
Query Neighborhood Hits	997	Target Neighborhood Hits	484	Shared Neighborhood Hits	180
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

FOXL2_HUMAN
θ value	1.81305 (rank : 619)	NC score	0.009883 (rank : 1242)
Query Neighborhood Hits	997	Target Neighborhood Hits	142	Shared Neighborhood Hits	40
SwissProt Accessions	P58012, Q4ZGJ3	Gene names	FOXL2
Domain Architecture
Description	Forkhead box protein L2.

GRAP_MOUSE
θ value	1.81305 (rank : 620)	NC score	0.037211 (rank : 1030)
Query Neighborhood Hits	997	Target Neighborhood Hits	309	Shared Neighborhood Hits	70
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

HIC1_MOUSE
θ value	1.81305 (rank : 621)	NC score	-0.007047 (rank : 1329)
Query Neighborhood Hits	997	Target Neighborhood Hits	863	Shared Neighborhood Hits	74
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).

IQEC3_MOUSE
θ value	1.81305 (rank : 622)	NC score	0.029536 (rank : 1086)
Query Neighborhood Hits	997	Target Neighborhood Hits	274	Shared Neighborhood Hits	93
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

LAD1_HUMAN
θ value	1.81305 (rank : 623)	NC score	0.063446 (rank : 654)
Query Neighborhood Hits	997	Target Neighborhood Hits	441	Shared Neighborhood Hits	103
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

LR37A_HUMAN
θ value	1.81305 (rank : 624)	NC score	0.051994 (rank : 878)
Query Neighborhood Hits	997	Target Neighborhood Hits	720	Shared Neighborhood Hits	167
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

LTB1L_MOUSE
θ value	1.81305 (rank : 625)	NC score	0.043388 (rank : 984)
Query Neighborhood Hits	997	Target Neighborhood Hits	514	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	1.81305 (rank : 626)	NC score	0.042888 (rank : 989)
Query Neighborhood Hits	997	Target Neighborhood Hits	479	Shared Neighborhood Hits	50
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MARCS_HUMAN
θ value	1.81305 (rank : 627)	NC score	0.092084 (rank : 453)
Query Neighborhood Hits	997	Target Neighborhood Hits	204	Shared Neighborhood Hits	79
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MK15_HUMAN
θ value	1.81305 (rank : 628)	NC score	0.034843 (rank : 1055)
Query Neighborhood Hits	997	Target Neighborhood Hits	1038	Shared Neighborhood Hits	162
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

MMP15_HUMAN
θ value	1.81305 (rank : 629)	NC score	0.005911 (rank : 1282)
Query Neighborhood Hits	997	Target Neighborhood Hits	95	Shared Neighborhood Hits	31
SwissProt Accessions	P51511, Q14111	Gene names	MMP15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP) (SMCP- 2).

NFM_HUMAN
θ value	1.81305 (rank : 630)	NC score	0.033053 (rank : 1068)
Query Neighborhood Hits	997	Target Neighborhood Hits	1328	Shared Neighborhood Hits	176
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

NRX2A_HUMAN
θ value	1.81305 (rank : 631)	NC score	0.045504 (rank : 968)
Query Neighborhood Hits	997	Target Neighborhood Hits	614	Shared Neighborhood Hits	201
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	1.81305 (rank : 632)	NC score	0.054672 (rank : 824)
Query Neighborhood Hits	997	Target Neighborhood Hits	481	Shared Neighborhood Hits	188
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

NUP53_HUMAN
θ value	1.81305 (rank : 633)	NC score	0.030442 (rank : 1080)
Query Neighborhood Hits	997	Target Neighborhood Hits	156	Shared Neighborhood Hits	65
SwissProt Accessions	Q8NFH5, Q4ZFZ9, Q53S95, Q8TDJ1	Gene names	NUP35, MP44, NUP53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

PME17_HUMAN
θ value	1.81305 (rank : 634)	NC score	0.019749 (rank : 1161)
Query Neighborhood Hits	997	Target Neighborhood Hits	95	Shared Neighborhood Hits	29
SwissProt Accessions	P40967, Q12763, Q14448, Q14817, Q16565	Gene names	SILV, D12S53E, PMEL17
Domain Architecture
Description	Melanocyte protein Pmel 17 precursor (Melanocyte lineage-specific antigen GP100) (Melanoma-associated ME20 antigen) (ME20M/ME20S) (ME20- M/ME20-S) (95 kDa melanocyte-specific secreted glycoprotein).

PO6F2_MOUSE
θ value	1.81305 (rank : 635)	NC score	0.036957 (rank : 1034)
Query Neighborhood Hits	997	Target Neighborhood Hits	639	Shared Neighborhood Hits	140
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

SELPL_MOUSE
θ value	1.81305 (rank : 636)	NC score	0.074990 (rank : 539)
Query Neighborhood Hits	997	Target Neighborhood Hits	588	Shared Neighborhood Hits	180
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SEM6B_MOUSE
θ value	1.81305 (rank : 637)	NC score	0.014894 (rank : 1203)
Query Neighborhood Hits	997	Target Neighborhood Hits	200	Shared Neighborhood Hits	79
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

SF3B4_HUMAN
θ value	1.81305 (rank : 638)	NC score	0.044650 (rank : 976)
Query Neighborhood Hits	997	Target Neighborhood Hits	445	Shared Neighborhood Hits	127
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

SMAD1_HUMAN
θ value	1.81305 (rank : 639)	NC score	0.014681 (rank : 1206)
Query Neighborhood Hits	997	Target Neighborhood Hits	59	Shared Neighborhood Hits	19
SwissProt Accessions	Q15797, Q16636	Gene names	SMAD1, BSP1, MADH1, MADR1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Transforming growth factor- beta signaling protein 1) (BSP-1) (hSMAD1) (JV4-1).

SOX13_HUMAN
θ value	1.81305 (rank : 640)	NC score	0.043172 (rank : 987)
Query Neighborhood Hits	997	Target Neighborhood Hits	464	Shared Neighborhood Hits	145
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

SP5_HUMAN
θ value	1.81305 (rank : 641)	NC score	-0.008368 (rank : 1332)
Query Neighborhood Hits	997	Target Neighborhood Hits	832	Shared Neighborhood Hits	85
SwissProt Accessions	Q6BEB4	Gene names	SP5
Domain Architecture	No domain graphic available
Description	Transcription factor Sp5.

SRA1_HUMAN
θ value	1.81305 (rank : 642)	NC score	0.027897 (rank : 1106)
Query Neighborhood Hits	997	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HD15, Q6NVU9, Q8IXM1, Q9HD13, Q9HD14	Gene names	SRA1
Domain Architecture	No domain graphic available
Description	Steroid receptor RNA activator 1 (Steroid receptor RNA activator protein) (SRAP).

SYN1_HUMAN
θ value	1.81305 (rank : 643)	NC score	0.112387 (rank : 372)
Query Neighborhood Hits	997	Target Neighborhood Hits	419	Shared Neighborhood Hits	207
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

TARA_HUMAN
θ value	1.81305 (rank : 644)	NC score	0.087927 (rank : 474)
Query Neighborhood Hits	997	Target Neighborhood Hits	1626	Shared Neighborhood Hits	306
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TR19L_HUMAN
θ value	1.81305 (rank : 645)	NC score	0.019245 (rank : 1169)
Query Neighborhood Hits	997	Target Neighborhood Hits	99	Shared Neighborhood Hits	21
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

TSC2_HUMAN
θ value	1.81305 (rank : 646)	NC score	0.008199 (rank : 1256)
Query Neighborhood Hits	997	Target Neighborhood Hits	59	Shared Neighborhood Hits	9
SwissProt Accessions	P49815, O75275, Q8TAZ1	Gene names	TSC2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 protein).

ULK1_HUMAN
θ value	1.81305 (rank : 647)	NC score	0.047270 (rank : 956)
Query Neighborhood Hits	997	Target Neighborhood Hits	1121	Shared Neighborhood Hits	208
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

URP2_MOUSE
θ value	1.81305 (rank : 648)	NC score	0.005398 (rank : 1289)
Query Neighborhood Hits	997	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K1B8	Gene names	Urp2, Kind3
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3).

WASF1_HUMAN
θ value	1.81305 (rank : 649)	NC score	0.089840 (rank : 463)
Query Neighborhood Hits	997	Target Neighborhood Hits	260	Shared Neighborhood Hits	148
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

WASF1_MOUSE
θ value	1.81305 (rank : 650)	NC score	0.092044 (rank : 454)
Query Neighborhood Hits	997	Target Neighborhood Hits	261	Shared Neighborhood Hits	145
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

WASIP_MOUSE
θ value	1.81305 (rank : 651)	NC score	0.187084 (rank : 299)
Query Neighborhood Hits	997	Target Neighborhood Hits	392	Shared Neighborhood Hits	211
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

WASL_MOUSE
θ value	1.81305 (rank : 652)	NC score	0.120648 (rank : 354)
Query Neighborhood Hits	997	Target Neighborhood Hits	339	Shared Neighborhood Hits	184
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WNK1_HUMAN
θ value	1.81305 (rank : 653)	NC score	0.054893 (rank : 820)
Query Neighborhood Hits	997	Target Neighborhood Hits	1158	Shared Neighborhood Hits	189
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

AAK1_MOUSE
θ value	2.36792 (rank : 654)	NC score	0.040391 (rank : 1003)
Query Neighborhood Hits	997	Target Neighborhood Hits	1051	Shared Neighborhood Hits	175
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

AFF1_HUMAN
θ value	2.36792 (rank : 655)	NC score	0.073533 (rank : 551)
Query Neighborhood Hits	997	Target Neighborhood Hits	506	Shared Neighborhood Hits	140
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

ARHG7_HUMAN
θ value	2.36792 (rank : 656)	NC score	0.035254 (rank : 1051)
Query Neighborhood Hits	997	Target Neighborhood Hits	347	Shared Neighborhood Hits	70
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

ATF6B_HUMAN
θ value	2.36792 (rank : 657)	NC score	0.016138 (rank : 1190)
Query Neighborhood Hits	997	Target Neighborhood Hits	122	Shared Neighborhood Hits	36
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).

BAI1_HUMAN
θ value	2.36792 (rank : 658)	NC score	0.015374 (rank : 1194)
Query Neighborhood Hits	997	Target Neighborhood Hits	375	Shared Neighborhood Hits	97
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAIP2_HUMAN
θ value	2.36792 (rank : 659)	NC score	0.018673 (rank : 1176)
Query Neighborhood Hits	997	Target Neighborhood Hits	192	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43	Gene names	BAIAP2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Protein BAP2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor substrate p53/p58) (IRSp53/58) (IRS-58) (Fas ligand-associated factor 3) (FLAF3).

BAT3_HUMAN
θ value	2.36792 (rank : 660)	NC score	0.085635 (rank : 483)
Query Neighborhood Hits	997	Target Neighborhood Hits	490	Shared Neighborhood Hits	211
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

CDT1_HUMAN
θ value	2.36792 (rank : 661)	NC score	0.032580 (rank : 1070)
Query Neighborhood Hits	997	Target Neighborhood Hits	92	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H211, Q86XX9, Q96CJ5, Q96GK5, Q96H67, Q96HE6, Q9BWM0	Gene names	CDT1
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP).

COBA2_MOUSE
θ value	2.36792 (rank : 662)	NC score	0.054772 (rank : 822)
Query Neighborhood Hits	997	Target Neighborhood Hits	501	Shared Neighborhood Hits	171
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

COCA1_MOUSE
θ value	2.36792 (rank : 663)	NC score	0.035676 (rank : 1046)
Query Neighborhood Hits	997	Target Neighborhood Hits	467	Shared Neighborhood Hits	135
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COHA1_HUMAN
θ value	2.36792 (rank : 664)	NC score	0.066252 (rank : 617)
Query Neighborhood Hits	997	Target Neighborhood Hits	400	Shared Neighborhood Hits	141
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

CRSP2_HUMAN
θ value	2.36792 (rank : 665)	NC score	0.061441 (rank : 685)
Query Neighborhood Hits	997	Target Neighborhood Hits	380	Shared Neighborhood Hits	144
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

CT055_HUMAN
θ value	2.36792 (rank : 666)	NC score	0.031494 (rank : 1075)
Query Neighborhood Hits	997	Target Neighborhood Hits	42	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BQ89	Gene names	C20orf55
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf55.

DHX37_HUMAN
θ value	2.36792 (rank : 667)	NC score	0.008949 (rank : 1249)
Query Neighborhood Hits	997	Target Neighborhood Hits	133	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IY37, Q9BUI7, Q9P211	Gene names	DHX37, DDX37, KIAA1517
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX37 (EC 3.6.1.-) (DEAH box protein 37).

DLG1_HUMAN
θ value	2.36792 (rank : 668)	NC score	0.003669 (rank : 1301)
Query Neighborhood Hits	997	Target Neighborhood Hits	290	Shared Neighborhood Hits	41
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DUS8_MOUSE
θ value	2.36792 (rank : 669)	NC score	0.017097 (rank : 1184)
Query Neighborhood Hits	997	Target Neighborhood Hits	119	Shared Neighborhood Hits	33
SwissProt Accessions	O09112	Gene names	Dusp8, Nttp1
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Neuronal tyrosine threonine phosphatase 1).

EDA_HUMAN
θ value	2.36792 (rank : 670)	NC score	0.044580 (rank : 977)
Query Neighborhood Hits	997	Target Neighborhood Hits	134	Shared Neighborhood Hits	73
SwissProt Accessions	Q92838, O75910, Q5JUM7, Q9UP77, Q9Y6L0, Q9Y6L1, Q9Y6L2, Q9Y6L3, Q9Y6L4	Gene names	EDA, ED1
Domain Architecture
Description	Ectodysplasin-A (Ectodermal dysplasia protein) (EDA protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

EDA_MOUSE
θ value	2.36792 (rank : 671)	NC score	0.045163 (rank : 973)
Query Neighborhood Hits	997	Target Neighborhood Hits	141	Shared Neighborhood Hits	72
SwissProt Accessions	O54693, O35705, Q9QWJ8, Q9QZ01, Q9QZ02	Gene names	Eda, Ed1, Ta
Domain Architecture
Description	Ectodysplasin-A (EDA protein homolog) (Tabby protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

FOXC2_HUMAN
θ value	2.36792 (rank : 672)	NC score	0.007741 (rank : 1262)
Query Neighborhood Hits	997	Target Neighborhood Hits	236	Shared Neighborhood Hits	68
SwissProt Accessions	Q99958	Gene names	FOXC2, FKHL14, MFH1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

FOXK1_MOUSE
θ value	2.36792 (rank : 673)	NC score	0.008269 (rank : 1255)
Query Neighborhood Hits	997	Target Neighborhood Hits	215	Shared Neighborhood Hits	54
SwissProt Accessions	P42128, O35939	Gene names	Foxk1, Mnf
Domain Architecture
Description	Forkhead box protein K1 (Myocyte nuclear factor) (MNF).

GAK10_HUMAN
θ value	2.36792 (rank : 674)	NC score	0.030945 (rank : 1076)
Query Neighborhood Hits	997	Target Neighborhood Hits	289	Shared Neighborhood Hits	102
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GR65_HUMAN
θ value	2.36792 (rank : 675)	NC score	0.032802 (rank : 1069)
Query Neighborhood Hits	997	Target Neighborhood Hits	148	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BQQ3, Q8N272, Q96H42	Gene names	GORASP1, GRASP65
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5).

HCN2_MOUSE
θ value	2.36792 (rank : 676)	NC score	0.035326 (rank : 1050)
Query Neighborhood Hits	997	Target Neighborhood Hits	278	Shared Neighborhood Hits	131
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

IRAK2_HUMAN
θ value	2.36792 (rank : 677)	NC score	0.065583 (rank : 629)
Query Neighborhood Hits	997	Target Neighborhood Hits	714	Shared Neighborhood Hits	83
SwissProt Accessions	O43187	Gene names	IRAK2
Domain Architecture
Description	Interleukin-1 receptor-associated kinase-like 2 (IRAK-2).

KPCE_HUMAN
θ value	2.36792 (rank : 678)	NC score	0.028219 (rank : 1103)
Query Neighborhood Hits	997	Target Neighborhood Hits	906	Shared Neighborhood Hits	88
SwissProt Accessions	Q02156, Q53SL4, Q53SM5, Q9UE81	Gene names	PRKCE, PKCE
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

LIPA3_HUMAN
θ value	2.36792 (rank : 679)	NC score	0.026833 (rank : 1115)
Query Neighborhood Hits	997	Target Neighborhood Hits	828	Shared Neighborhood Hits	84
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

MAVS_MOUSE
θ value	2.36792 (rank : 680)	NC score	0.031704 (rank : 1074)
Query Neighborhood Hits	997	Target Neighborhood Hits	170	Shared Neighborhood Hits	55
SwissProt Accessions	Q8VCF0	Gene names	Mavs, Ips1, Visa
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif).

MLL4_HUMAN
θ value	2.36792 (rank : 681)	NC score	0.112733 (rank : 369)
Query Neighborhood Hits	997	Target Neighborhood Hits	722	Shared Neighborhood Hits	257
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MMP9_HUMAN
θ value	2.36792 (rank : 682)	NC score	0.012226 (rank : 1226)
Query Neighborhood Hits	997	Target Neighborhood Hits	125	Shared Neighborhood Hits	33
SwissProt Accessions	P14780, Q3LR70, Q8N725, Q9H4Z1	Gene names	MMP9, CLG4B
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB) [Contains: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9].

MYLK_MOUSE
θ value	2.36792 (rank : 683)	NC score	0.042261 (rank : 993)
Query Neighborhood Hits	997	Target Neighborhood Hits	1489	Shared Neighborhood Hits	198
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

NFRKB_MOUSE
θ value	2.36792 (rank : 684)	NC score	0.055788 (rank : 808)
Query Neighborhood Hits	997	Target Neighborhood Hits	393	Shared Neighborhood Hits	121
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

PAK4_MOUSE
θ value	2.36792 (rank : 685)	NC score	0.044697 (rank : 975)
Query Neighborhood Hits	997	Target Neighborhood Hits	1098	Shared Neighborhood Hits	198
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

PELP1_MOUSE
θ value	2.36792 (rank : 686)	NC score	0.094740 (rank : 443)
Query Neighborhood Hits	997	Target Neighborhood Hits	709	Shared Neighborhood Hits	236
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PGCB_MOUSE
θ value	2.36792 (rank : 687)	NC score	0.027081 (rank : 1111)
Query Neighborhood Hits	997	Target Neighborhood Hits	459	Shared Neighborhood Hits	53
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

PRGC2_MOUSE
θ value	2.36792 (rank : 688)	NC score	0.027248 (rank : 1108)
Query Neighborhood Hits	997	Target Neighborhood Hits	225	Shared Neighborhood Hits	48
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

RBL2_HUMAN
θ value	2.36792 (rank : 689)	NC score	0.007116 (rank : 1266)
Query Neighborhood Hits	997	Target Neighborhood Hits	44	Shared Neighborhood Hits	12
SwissProt Accessions	Q08999, Q15073, Q16084, Q92812	Gene names	RBL2, RB2
Domain Architecture
Description	Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (PRB2) (P130) (RBR-2).

RBM19_HUMAN
θ value	2.36792 (rank : 690)	NC score	-0.002032 (rank : 1320)
Query Neighborhood Hits	997	Target Neighborhood Hits	331	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y4C8, Q9BPY6, Q9UFN5	Gene names	RBM19, KIAA0682
Domain Architecture
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

RERE_HUMAN
θ value	2.36792 (rank : 691)	NC score	0.124082 (rank : 348)
Query Neighborhood Hits	997	Target Neighborhood Hits	779	Shared Neighborhood Hits	269
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RERE_MOUSE
θ value	2.36792 (rank : 692)	NC score	0.122415 (rank : 353)
Query Neighborhood Hits	997	Target Neighborhood Hits	785	Shared Neighborhood Hits	260
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SFR15_HUMAN
θ value	2.36792 (rank : 693)	NC score	0.084144 (rank : 487)
Query Neighborhood Hits	997	Target Neighborhood Hits	368	Shared Neighborhood Hits	135
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SNPC4_MOUSE
θ value	2.36792 (rank : 694)	NC score	0.025794 (rank : 1124)
Query Neighborhood Hits	997	Target Neighborhood Hits	237	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

SON_MOUSE
θ value	2.36792 (rank : 695)	NC score	0.112552 (rank : 371)
Query Neighborhood Hits	997	Target Neighborhood Hits	957	Shared Neighborhood Hits	283
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

TLE1_HUMAN
θ value	2.36792 (rank : 696)	NC score	0.015030 (rank : 1200)
Query Neighborhood Hits	997	Target Neighborhood Hits	485	Shared Neighborhood Hits	116
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

TMM24_MOUSE
θ value	2.36792 (rank : 697)	NC score	0.012220 (rank : 1227)
Query Neighborhood Hits	997	Target Neighborhood Hits	65	Shared Neighborhood Hits	18
SwissProt Accessions	Q80X80	Gene names	Tmem24
Domain Architecture	No domain graphic available
Description	Transmembrane protein 24.

WASL_HUMAN
θ value	2.36792 (rank : 698)	NC score	0.116572 (rank : 361)
Query Neighborhood Hits	997	Target Neighborhood Hits	312	Shared Neighborhood Hits	178
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

ZAR1_HUMAN
θ value	2.36792 (rank : 699)	NC score	0.035532 (rank : 1049)
Query Neighborhood Hits	997	Target Neighborhood Hits	163	Shared Neighborhood Hits	68
SwissProt Accessions	Q86SH2	Gene names	ZAR1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

ZN395_HUMAN
θ value	2.36792 (rank : 700)	NC score	0.024013 (rank : 1133)
Query Neighborhood Hits	997	Target Neighborhood Hits	64	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H8N7, Q6F6H2, Q9BY72, Q9NPB2, Q9NS57, Q9NS58, Q9NS59	Gene names	ZNF395, HDBP2, PBF
Domain Architecture	No domain graphic available
Description	Zinc finger protein 395 (Papillomavirus-binding factor) (Papillomavirus regulatory factor 1) (PRF-1) (Huntington disease gene regulatory region-binding protein 2) (HDBP-2) (HD gene regulatory region-binding protein 2) (HD-regulating factor 2) (HDRF-2).

ACK1_MOUSE
θ value	3.0926 (rank : 701)	NC score	0.075231 (rank : 537)
Query Neighborhood Hits	997	Target Neighborhood Hits	1080	Shared Neighborhood Hits	224
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

ALEX_MOUSE
θ value	3.0926 (rank : 702)	NC score	0.072454 (rank : 559)
Query Neighborhood Hits	997	Target Neighborhood Hits	197	Shared Neighborhood Hits	97
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ARI3A_HUMAN
θ value	3.0926 (rank : 703)	NC score	0.014592 (rank : 1207)
Query Neighborhood Hits	997	Target Neighborhood Hits	80	Shared Neighborhood Hits	22
SwissProt Accessions	Q99856, Q8IZA7	Gene names	ARID3A, DRIL1, DRX, E2FBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 3A (ARID domain- containing protein 3A) (B-cell regulator of IgH transcription) (Bright) (E2F-binding protein 1).

ATBF1_MOUSE
θ value	3.0926 (rank : 704)	NC score	0.011717 (rank : 1231)
Query Neighborhood Hits	997	Target Neighborhood Hits	1841	Shared Neighborhood Hits	239
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

ATX7_MOUSE
θ value	3.0926 (rank : 705)	NC score	0.060390 (rank : 715)
Query Neighborhood Hits	997	Target Neighborhood Hits	328	Shared Neighborhood Hits	142
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

BAIP2_MOUSE
θ value	3.0926 (rank : 706)	NC score	0.016506 (rank : 1188)
Query Neighborhood Hits	997	Target Neighborhood Hits	185	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BKX1, Q91V97, Q923V9, Q923W0	Gene names	Baiap2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor tyrosine kinase 53 kDa substrate).

BAT2_HUMAN
θ value	3.0926 (rank : 707)	NC score	0.148100 (rank : 319)
Query Neighborhood Hits	997	Target Neighborhood Hits	931	Shared Neighborhood Hits	328
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BCL6_MOUSE
θ value	3.0926 (rank : 708)	NC score	-0.011375 (rank : 1336)
Query Neighborhood Hits	997	Target Neighborhood Hits	913	Shared Neighborhood Hits	74
SwissProt Accessions	P41183, Q61065	Gene names	Bcl6, Bcl-6
Domain Architecture
Description	B-cell lymphoma 6 protein homolog.

CABL2_MOUSE
θ value	3.0926 (rank : 709)	NC score	0.028790 (rank : 1094)
Query Neighborhood Hits	997	Target Neighborhood Hits	79	Shared Neighborhood Hits	39
SwissProt Accessions	Q8K3M5	Gene names	Cables2
Domain Architecture
Description	CDK5 and ABL1 enzyme substrate 2 (Interactor with CDK3 2) (Ik3-2).

CBP_MOUSE
θ value	3.0926 (rank : 710)	NC score	0.099048 (rank : 426)
Query Neighborhood Hits	997	Target Neighborhood Hits	1051	Shared Neighborhood Hits	301
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CEBPE_HUMAN
θ value	3.0926 (rank : 711)	NC score	0.014136 (rank : 1211)
Query Neighborhood Hits	997	Target Neighborhood Hits	236	Shared Neighborhood Hits	63
SwissProt Accessions	Q15744, Q15745, Q8IYI2, Q99803	Gene names	CEBPE
Domain Architecture
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

CO6A1_HUMAN
θ value	3.0926 (rank : 712)	NC score	0.033132 (rank : 1067)
Query Neighborhood Hits	997	Target Neighborhood Hits	264	Shared Neighborhood Hits	83
SwissProt Accessions	P12109, O00117, O00118, Q14040, Q14041, Q16258	Gene names	COL6A1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

CO8A2_HUMAN
θ value	3.0926 (rank : 713)	NC score	0.053912 (rank : 832)
Query Neighborhood Hits	997	Target Neighborhood Hits	299	Shared Neighborhood Hits	131
SwissProt Accessions	P25067, Q8TEJ5	Gene names	COL8A2
Domain Architecture
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

COCA1_HUMAN
θ value	3.0926 (rank : 714)	NC score	0.033508 (rank : 1061)
Query Neighborhood Hits	997	Target Neighborhood Hits	458	Shared Neighborhood Hits	125
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COEA1_MOUSE
θ value	3.0926 (rank : 715)	NC score	0.029006 (rank : 1092)
Query Neighborhood Hits	997	Target Neighborhood Hits	402	Shared Neighborhood Hits	107
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

COIA1_HUMAN
θ value	3.0926 (rank : 716)	NC score	0.068678 (rank : 592)
Query Neighborhood Hits	997	Target Neighborhood Hits	447	Shared Neighborhood Hits	184
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CT055_MOUSE
θ value	3.0926 (rank : 717)	NC score	0.043857 (rank : 982)
Query Neighborhood Hits	997	Target Neighborhood Hits	52	Shared Neighborhood Hits	33
SwissProt Accessions	Q8R184, Q8BQE5, Q8K024, Q8VEM7, Q9CU80	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf55 homolog.

DCP1A_HUMAN
θ value	3.0926 (rank : 718)	NC score	0.035101 (rank : 1053)
Query Neighborhood Hits	997	Target Neighborhood Hits	228	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

DUS8_HUMAN
θ value	3.0926 (rank : 719)	NC score	0.020456 (rank : 1159)
Query Neighborhood Hits	997	Target Neighborhood Hits	161	Shared Neighborhood Hits	60
SwissProt Accessions	Q13202	Gene names	DUSP8, VH5
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH-5).

FRS3_MOUSE
θ value	3.0926 (rank : 720)	NC score	0.027008 (rank : 1114)
Query Neighborhood Hits	997	Target Neighborhood Hits	168	Shared Neighborhood Hits	78
SwissProt Accessions	Q91WJ0	Gene names	Frs3, Frs2b
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FRS2-beta).

GGN_MOUSE
θ value	3.0926 (rank : 721)	NC score	0.124419 (rank : 347)
Query Neighborhood Hits	997	Target Neighborhood Hits	311	Shared Neighborhood Hits	155
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

HDAC6_HUMAN
θ value	3.0926 (rank : 722)	NC score	0.007682 (rank : 1263)
Query Neighborhood Hits	997	Target Neighborhood Hits	145	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UBN7	Gene names	HDAC6
Domain Architecture
Description	Histone deacetylase 6 (HD6).

KPCE_MOUSE
θ value	3.0926 (rank : 723)	NC score	0.028361 (rank : 1101)
Query Neighborhood Hits	997	Target Neighborhood Hits	906	Shared Neighborhood Hits	87
SwissProt Accessions	P16054	Gene names	Prkce, Pkce, Pkcea
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

LIPB2_HUMAN
θ value	3.0926 (rank : 724)	NC score	0.050455 (rank : 922)
Query Neighborhood Hits	997	Target Neighborhood Hits	599	Shared Neighborhood Hits	68
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

LTBP4_MOUSE
θ value	3.0926 (rank : 725)	NC score	0.056782 (rank : 795)
Query Neighborhood Hits	997	Target Neighborhood Hits	607	Shared Neighborhood Hits	109
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

MA1B1_HUMAN
θ value	3.0926 (rank : 726)	NC score	0.018148 (rank : 1179)
Query Neighborhood Hits	997	Target Neighborhood Hits	125	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UKM7, Q5VSG3, Q9BRS9, Q9Y5K7	Gene names	MAN1B1
Domain Architecture
Description	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific-processing alpha-mannosidase).

MLL2_HUMAN
θ value	3.0926 (rank : 727)	NC score	0.129912 (rank : 339)
Query Neighborhood Hits	997	Target Neighborhood Hits	1788	Shared Neighborhood Hits	433
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

NBR1_MOUSE
θ value	3.0926 (rank : 728)	NC score	0.022993 (rank : 1140)
Query Neighborhood Hits	997	Target Neighborhood Hits	116	Shared Neighborhood Hits	25
SwissProt Accessions	P97432, Q9JIH9	Gene names	Nbr1, M17s2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2).

NFAC2_MOUSE
θ value	3.0926 (rank : 729)	NC score	0.011234 (rank : 1235)
Query Neighborhood Hits	997	Target Neighborhood Hits	98	Shared Neighborhood Hits	28
SwissProt Accessions	Q60591, Q60984, Q60985	Gene names	Nfatc2, Nfat1, Nfatp
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).

OBF1_MOUSE
θ value	3.0926 (rank : 730)	NC score	0.017656 (rank : 1181)
Query Neighborhood Hits	997	Target Neighborhood Hits	73	Shared Neighborhood Hits	22
SwissProt Accessions	Q64693	Gene names	Pou2af1, Obf-1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (BOB1) (OCA-B).

PCNT_MOUSE
θ value	3.0926 (rank : 731)	NC score	0.024423 (rank : 1130)
Query Neighborhood Hits	997	Target Neighborhood Hits	1207	Shared Neighborhood Hits	95
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

PDE3A_MOUSE
θ value	3.0926 (rank : 732)	NC score	0.005116 (rank : 1290)
Query Neighborhood Hits	997	Target Neighborhood Hits	115	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z0X4	Gene names	Pde3a
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

PDLI5_HUMAN
θ value	3.0926 (rank : 733)	NC score	0.007097 (rank : 1268)
Query Neighborhood Hits	997	Target Neighborhood Hits	322	Shared Neighborhood Hits	46
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PHF12_MOUSE
θ value	3.0926 (rank : 734)	NC score	0.012610 (rank : 1223)
Query Neighborhood Hits	997	Target Neighborhood Hits	172	Shared Neighborhood Hits	39
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PP1R8_HUMAN
θ value	3.0926 (rank : 735)	NC score	0.014218 (rank : 1210)
Query Neighborhood Hits	997	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	Q12972, Q5TIF2, Q6PKF6, Q9UBH1, Q9UBZ0	Gene names	PPP1R8, ARD1, NIPP1
Domain Architecture
Description	Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8) [Includes: Activator of RNA decay (EC 3.1.4.-) (ARD-1)].

RAVR1_MOUSE
θ value	3.0926 (rank : 736)	NC score	0.010087 (rank : 1241)
Query Neighborhood Hits	997	Target Neighborhood Hits	179	Shared Neighborhood Hits	29
SwissProt Accessions	Q9CW46, Q5DTT6, Q811K0, Q8C3Z1, Q8CA14	Gene names	Raver1, Kiaa1978
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 1 (Protein raver-1).

RPGF1_HUMAN
θ value	3.0926 (rank : 737)	NC score	0.012705 (rank : 1221)
Query Neighborhood Hits	997	Target Neighborhood Hits	262	Shared Neighborhood Hits	82
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

SFTA1_HUMAN
θ value	3.0926 (rank : 738)	NC score	0.025868 (rank : 1122)
Query Neighborhood Hits	997	Target Neighborhood Hits	169	Shared Neighborhood Hits	55
SwissProt Accessions	Q8IWL2, P07714, Q5RIR5, Q5RIR7, Q6PIT0, Q8TC19	Gene names	SFTPA1, PSAP, SFTP1, SFTPA
Domain Architecture	No domain graphic available
Description	Pulmonary surfactant-associated protein A1 precursor (SP-A1) (SP-A) (PSP-A) (PSPA) (Alveolar proteinosis protein) (35 kDa pulmonary surfactant-associated protein).

SGIP1_MOUSE
θ value	3.0926 (rank : 739)	NC score	0.079609 (rank : 506)
Query Neighborhood Hits	997	Target Neighborhood Hits	180	Shared Neighborhood Hits	96
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SNIP_MOUSE
θ value	3.0926 (rank : 740)	NC score	0.039983 (rank : 1005)
Query Neighborhood Hits	997	Target Neighborhood Hits	319	Shared Neighborhood Hits	78
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

SOX5_MOUSE
θ value	3.0926 (rank : 741)	NC score	0.008966 (rank : 1248)
Query Neighborhood Hits	997	Target Neighborhood Hits	196	Shared Neighborhood Hits	26
SwissProt Accessions	P35710, O88184, O89018	Gene names	Sox5, Sox-5
Domain Architecture
Description	Transcription factor SOX-5.

SYN2_HUMAN
θ value	3.0926 (rank : 742)	NC score	0.057219 (rank : 791)
Query Neighborhood Hits	997	Target Neighborhood Hits	213	Shared Neighborhood Hits	115
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

SYNJ1_HUMAN
θ value	3.0926 (rank : 743)	NC score	0.084061 (rank : 489)
Query Neighborhood Hits	997	Target Neighborhood Hits	498	Shared Neighborhood Hits	206
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TACC2_HUMAN
θ value	3.0926 (rank : 744)	NC score	0.052199 (rank : 872)
Query Neighborhood Hits	997	Target Neighborhood Hits	856	Shared Neighborhood Hits	152
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

TB182_HUMAN
θ value	3.0926 (rank : 745)	NC score	0.077295 (rank : 517)
Query Neighborhood Hits	997	Target Neighborhood Hits	414	Shared Neighborhood Hits	145
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

ZBT47_HUMAN
θ value	3.0926 (rank : 746)	NC score	-0.013494 (rank : 1338)
Query Neighborhood Hits	997	Target Neighborhood Hits	737	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UFB7, Q8WTY8, Q9ULN0	Gene names	ZBTB47, KIAA1190, ZNF651
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 47 (Zinc finger protein 651).

ZMYM3_HUMAN
θ value	3.0926 (rank : 747)	NC score	0.027228 (rank : 1109)
Query Neighborhood Hits	997	Target Neighborhood Hits	223	Shared Neighborhood Hits	57
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

ZN142_HUMAN
θ value	3.0926 (rank : 748)	NC score	-0.008024 (rank : 1331)
Query Neighborhood Hits	997	Target Neighborhood Hits	1007	Shared Neighborhood Hits	134
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).

ZN438_HUMAN
θ value	3.0926 (rank : 749)	NC score	0.000275 (rank : 1314)
Query Neighborhood Hits	997	Target Neighborhood Hits	906	Shared Neighborhood Hits	101
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

3BP1_HUMAN
θ value	4.03905 (rank : 750)	NC score	0.075594 (rank : 531)
Query Neighborhood Hits	997	Target Neighborhood Hits	376	Shared Neighborhood Hits	157
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

3BP2_HUMAN
θ value	4.03905 (rank : 751)	NC score	0.044943 (rank : 974)
Query Neighborhood Hits	997	Target Neighborhood Hits	296	Shared Neighborhood Hits	115
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

ABL1_HUMAN
θ value	4.03905 (rank : 752)	NC score	0.064921 (rank : 637)
Query Neighborhood Hits	997	Target Neighborhood Hits	1220	Shared Neighborhood Hits	193
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABR_HUMAN
θ value	4.03905 (rank : 753)	NC score	0.007112 (rank : 1267)
Query Neighborhood Hits	997	Target Neighborhood Hits	166	Shared Neighborhood Hits	29
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

AKAP1_MOUSE
θ value	4.03905 (rank : 754)	NC score	0.016602 (rank : 1187)
Query Neighborhood Hits	997	Target Neighborhood Hits	198	Shared Neighborhood Hits	49
SwissProt Accessions	O08715, O08714, P97488	Gene names	Akap1, Akap
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein) (S-AKAP).

AKAP6_HUMAN
θ value	4.03905 (rank : 755)	NC score	0.015218 (rank : 1197)
Query Neighborhood Hits	997	Target Neighborhood Hits	263	Shared Neighborhood Hits	26
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

APXL_HUMAN
θ value	4.03905 (rank : 756)	NC score	0.052951 (rank : 855)
Query Neighborhood Hits	997	Target Neighborhood Hits	553	Shared Neighborhood Hits	141
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

ARRD1_HUMAN
θ value	4.03905 (rank : 757)	NC score	0.022427 (rank : 1143)
Query Neighborhood Hits	997	Target Neighborhood Hits	75	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N5I2	Gene names	ARRDC1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

ASTL_HUMAN
θ value	4.03905 (rank : 758)	NC score	0.041244 (rank : 999)
Query Neighborhood Hits	997	Target Neighborhood Hits	252	Shared Neighborhood Hits	95
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

ATF7_HUMAN
θ value	4.03905 (rank : 759)	NC score	0.016630 (rank : 1186)
Query Neighborhood Hits	997	Target Neighborhood Hits	333	Shared Neighborhood Hits	55
SwissProt Accessions	P17544, Q13814	Gene names	ATF7, ATFA
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

BAZ2A_HUMAN
θ value	4.03905 (rank : 760)	NC score	0.038859 (rank : 1013)
Query Neighborhood Hits	997	Target Neighborhood Hits	780	Shared Neighborhood Hits	167
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

CD2AP_MOUSE
θ value	4.03905 (rank : 761)	NC score	0.053735 (rank : 834)
Query Neighborhood Hits	997	Target Neighborhood Hits	336	Shared Neighborhood Hits	98
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

CDKL5_HUMAN
θ value	4.03905 (rank : 762)	NC score	0.026527 (rank : 1119)
Query Neighborhood Hits	997	Target Neighborhood Hits	967	Shared Neighborhood Hits	100
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

CNGB1_HUMAN
θ value	4.03905 (rank : 763)	NC score	0.014798 (rank : 1204)
Query Neighborhood Hits	997	Target Neighborhood Hits	222	Shared Neighborhood Hits	50
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNKR2_HUMAN
θ value	4.03905 (rank : 764)	NC score	0.045700 (rank : 967)
Query Neighborhood Hits	997	Target Neighborhood Hits	197	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	4.03905 (rank : 765)	NC score	0.045738 (rank : 966)
Query Neighborhood Hits	997	Target Neighborhood Hits	197	Shared Neighborhood Hits	36
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CO1A1_HUMAN
θ value	4.03905 (rank : 766)	NC score	0.071536 (rank : 569)
Query Neighborhood Hits	997	Target Neighborhood Hits	475	Shared Neighborhood Hits	171
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO1A2_HUMAN
θ value	4.03905 (rank : 767)	NC score	0.052218 (rank : 871)
Query Neighborhood Hits	997	Target Neighborhood Hits	329	Shared Neighborhood Hits	130
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO4A1_HUMAN
θ value	4.03905 (rank : 768)	NC score	0.053099 (rank : 850)
Query Neighborhood Hits	997	Target Neighborhood Hits	425	Shared Neighborhood Hits	163
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

CO7A1_HUMAN
θ value	4.03905 (rank : 769)	NC score	0.061014 (rank : 693)
Query Neighborhood Hits	997	Target Neighborhood Hits	807	Shared Neighborhood Hits	226
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

COBA2_HUMAN
θ value	4.03905 (rank : 770)	NC score	0.059143 (rank : 744)
Query Neighborhood Hits	997	Target Neighborhood Hits	408	Shared Neighborhood Hits	149
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

CTND2_HUMAN
θ value	4.03905 (rank : 771)	NC score	0.021697 (rank : 1148)
Query Neighborhood Hits	997	Target Neighborhood Hits	333	Shared Neighborhood Hits	95
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

ECM1_MOUSE
θ value	4.03905 (rank : 772)	NC score	0.020272 (rank : 1160)
Query Neighborhood Hits	997	Target Neighborhood Hits	105	Shared Neighborhood Hits	35
SwissProt Accessions	Q61508	Gene names	Ecm1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

EGLN1_MOUSE
θ value	4.03905 (rank : 773)	NC score	0.019466 (rank : 1165)
Query Neighborhood Hits	997	Target Neighborhood Hits	88	Shared Neighborhood Hits	31
SwissProt Accessions	Q91YE3, Q8VHJ2, Q922P3	Gene names	Egln1
Domain Architecture
Description	Egl nine homolog 1 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-prolyl hydroxylase 2) (HIF-PH2) (HPH-2) (SM-20).

EMIL1_HUMAN
θ value	4.03905 (rank : 774)	NC score	0.018826 (rank : 1172)
Query Neighborhood Hits	997	Target Neighborhood Hits	239	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y6C2, Q96G58, Q9UG76	Gene names	EMILIN1, EMI
Domain Architecture
Description	EMILIN-1 precursor (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1).

EPN3_MOUSE
θ value	4.03905 (rank : 775)	NC score	0.041187 (rank : 1000)
Query Neighborhood Hits	997	Target Neighborhood Hits	312	Shared Neighborhood Hits	121
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

ERR1_HUMAN
θ value	4.03905 (rank : 776)	NC score	0.004525 (rank : 1292)
Query Neighborhood Hits	997	Target Neighborhood Hits	157	Shared Neighborhood Hits	35
SwissProt Accessions	P11474, Q14514	Gene names	ESRRA, ERR1, ESRL1, NR3B1
Domain Architecture
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR- alpha) (Estrogen receptor-like 1).

FOG1_HUMAN
θ value	4.03905 (rank : 777)	NC score	0.021894 (rank : 1147)
Query Neighborhood Hits	997	Target Neighborhood Hits	981	Shared Neighborhood Hits	156
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

FOXP4_HUMAN
θ value	4.03905 (rank : 778)	NC score	0.006540 (rank : 1275)
Query Neighborhood Hits	997	Target Neighborhood Hits	246	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IVH2, Q96E19	Gene names	FOXP4, FKHLA
Domain Architecture
Description	Forkhead box protein P4 (Fork head-related protein-like A).

HCN4_HUMAN
θ value	4.03905 (rank : 779)	NC score	0.033920 (rank : 1058)
Query Neighborhood Hits	997	Target Neighborhood Hits	303	Shared Neighborhood Hits	130
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

KCNH6_HUMAN
θ value	4.03905 (rank : 780)	NC score	0.010133 (rank : 1240)
Query Neighborhood Hits	997	Target Neighborhood Hits	222	Shared Neighborhood Hits	64
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KLF17_HUMAN
θ value	4.03905 (rank : 781)	NC score	-0.004067 (rank : 1322)
Query Neighborhood Hits	997	Target Neighborhood Hits	882	Shared Neighborhood Hits	126
SwissProt Accessions	Q5JT82, Q86VQ7, Q8N805	Gene names	KLF17, ZNF393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393).

LRC56_HUMAN
θ value	4.03905 (rank : 782)	NC score	0.023043 (rank : 1139)
Query Neighborhood Hits	997	Target Neighborhood Hits	165	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IYG6, Q8N3Q4	Gene names	LRRC56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

MAP2_HUMAN
θ value	4.03905 (rank : 783)	NC score	0.036039 (rank : 1042)
Query Neighborhood Hits	997	Target Neighborhood Hits	348	Shared Neighborhood Hits	80
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

MFRN2_MOUSE
θ value	4.03905 (rank : 784)	NC score	-0.000325 (rank : 1316)
Query Neighborhood Hits	997	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R0Z5, Q8K4J8, Q8K4J9, Q8R578	Gene names	Slc25a28, Mfrn2
Domain Architecture	No domain graphic available
Description	Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute carrier family 25 member 28) (Mitochondrial RNA-splicing protein 3/4 homolog) (MRS3/4).

MORC4_MOUSE
θ value	4.03905 (rank : 785)	NC score	0.009416 (rank : 1246)
Query Neighborhood Hits	997	Target Neighborhood Hits	235	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BMD7, Q4KMM6, Q8BX95, Q9CS96	Gene names	Morc4, Zcwcc2
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 4 (Zinc finger CW-type coiled- coil domain protein 2).

MYO1F_HUMAN
θ value	4.03905 (rank : 786)	NC score	0.019495 (rank : 1163)
Query Neighborhood Hits	997	Target Neighborhood Hits	275	Shared Neighborhood Hits	80
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

NALP1_HUMAN
θ value	4.03905 (rank : 787)	NC score	0.004211 (rank : 1295)
Query Neighborhood Hits	997	Target Neighborhood Hits	138	Shared Neighborhood Hits	28
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

PO6F1_MOUSE
θ value	4.03905 (rank : 788)	NC score	0.013929 (rank : 1213)
Query Neighborhood Hits	997	Target Neighborhood Hits	581	Shared Neighborhood Hits	102
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

PTN23_HUMAN
θ value	4.03905 (rank : 789)	NC score	0.058244 (rank : 766)
Query Neighborhood Hits	997	Target Neighborhood Hits	646	Shared Neighborhood Hits	198
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

QSCN6_MOUSE
θ value	4.03905 (rank : 790)	NC score	0.003702 (rank : 1300)
Query Neighborhood Hits	997	Target Neighborhood Hits	62	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BND5, Q3TDY9, Q3TE19, Q3TR29, Q3UEL4, Q8K041, Q9DBL6	Gene names	Qscn6, Sox
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 1 precursor (EC 1.8.3.2) (Quiescin Q6) (Skin sulfhydryl oxidase) (mSOx).

RAD52_HUMAN
θ value	4.03905 (rank : 791)	NC score	0.008357 (rank : 1254)
Query Neighborhood Hits	997	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	P43351, Q13205	Gene names	RAD52
Domain Architecture
Description	DNA repair protein RAD52 homolog.

RP3A_MOUSE
θ value	4.03905 (rank : 792)	NC score	0.028387 (rank : 1099)
Query Neighborhood Hits	997	Target Neighborhood Hits	510	Shared Neighborhood Hits	164
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SETBP_MOUSE
θ value	4.03905 (rank : 793)	NC score	0.042751 (rank : 990)
Query Neighborhood Hits	997	Target Neighborhood Hits	352	Shared Neighborhood Hits	111
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SFPQ_HUMAN
θ value	4.03905 (rank : 794)	NC score	0.099228 (rank : 424)
Query Neighborhood Hits	997	Target Neighborhood Hits	986	Shared Neighborhood Hits	273
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SMAD1_MOUSE
θ value	4.03905 (rank : 795)	NC score	0.013365 (rank : 1216)
Query Neighborhood Hits	997	Target Neighborhood Hits	56	Shared Neighborhood Hits	18
SwissProt Accessions	P70340, P70442, Q9CYK6	Gene names	Smad1, Madh1, Madr1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Mothers-against-DPP-related 1) (mMad1) (Dwarfin-A) (Dwf-A).

SMAL1_HUMAN
θ value	4.03905 (rank : 796)	NC score	0.010894 (rank : 1238)
Query Neighborhood Hits	997	Target Neighborhood Hits	174	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

SNPC4_HUMAN
θ value	4.03905 (rank : 797)	NC score	0.083371 (rank : 495)
Query Neighborhood Hits	997	Target Neighborhood Hits	589	Shared Neighborhood Hits	220
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

SPRR3_MOUSE
θ value	4.03905 (rank : 798)	NC score	0.052899 (rank : 857)
Query Neighborhood Hits	997	Target Neighborhood Hits	106	Shared Neighborhood Hits	45
SwissProt Accessions	O09116	Gene names	Sprr3
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta).

TAU_HUMAN
θ value	4.03905 (rank : 799)	NC score	0.089884 (rank : 462)
Query Neighborhood Hits	997	Target Neighborhood Hits	448	Shared Neighborhood Hits	203
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TENS1_HUMAN
θ value	4.03905 (rank : 800)	NC score	0.034786 (rank : 1056)
Query Neighborhood Hits	997	Target Neighborhood Hits	400	Shared Neighborhood Hits	110
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

TF3C2_MOUSE
θ value	4.03905 (rank : 801)	NC score	0.015930 (rank : 1191)
Query Neighborhood Hits	997	Target Neighborhood Hits	165	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BL74, Q3U7Z9, Q80XQ7, Q8BJJ4, Q8BLP3, Q8K1J1, Q9CSS0, Q9CVE6, Q9DBK6	Gene names	Gtf3c2, Kiaa0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

TGON2_MOUSE
θ value	4.03905 (rank : 802)	NC score	0.036019 (rank : 1043)
Query Neighborhood Hits	997	Target Neighborhood Hits	277	Shared Neighborhood Hits	64
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

TLE1_MOUSE
θ value	4.03905 (rank : 803)	NC score	0.014125 (rank : 1212)
Query Neighborhood Hits	997	Target Neighborhood Hits	491	Shared Neighborhood Hits	116
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

TP53B_HUMAN
θ value	4.03905 (rank : 804)	NC score	0.028965 (rank : 1093)
Query Neighborhood Hits	997	Target Neighborhood Hits	413	Shared Neighborhood Hits	68
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

WASF3_MOUSE
θ value	4.03905 (rank : 805)	NC score	0.071466 (rank : 570)
Query Neighborhood Hits	997	Target Neighborhood Hits	188	Shared Neighborhood Hits	100
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

YETS2_MOUSE
θ value	4.03905 (rank : 806)	NC score	0.028173 (rank : 1104)
Query Neighborhood Hits	997	Target Neighborhood Hits	278	Shared Neighborhood Hits	79
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

3BP2_MOUSE
θ value	5.27518 (rank : 807)	NC score	0.030756 (rank : 1078)
Query Neighborhood Hits	997	Target Neighborhood Hits	142	Shared Neighborhood Hits	43
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

AHI1_MOUSE
θ value	5.27518 (rank : 808)	NC score	0.025245 (rank : 1127)
Query Neighborhood Hits	997	Target Neighborhood Hits	496	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

BOC_HUMAN
θ value	5.27518 (rank : 809)	NC score	0.005665 (rank : 1287)
Query Neighborhood Hits	997	Target Neighborhood Hits	543	Shared Neighborhood Hits	83
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

CENG3_HUMAN
θ value	5.27518 (rank : 810)	NC score	0.307768 (rank : 279)
Query Neighborhood Hits	997	Target Neighborhood Hits	455	Shared Neighborhood Hits	243
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_MOUSE
θ value	5.27518 (rank : 811)	NC score	0.307801 (rank : 278)
Query Neighborhood Hits	997	Target Neighborhood Hits	467	Shared Neighborhood Hits	242
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CNOT3_MOUSE
θ value	5.27518 (rank : 812)	NC score	0.072759 (rank : 555)
Query Neighborhood Hits	997	Target Neighborhood Hits	504	Shared Neighborhood Hits	136
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CO1A1_MOUSE
θ value	5.27518 (rank : 813)	NC score	0.072252 (rank : 561)
Query Neighborhood Hits	997	Target Neighborhood Hits	457	Shared Neighborhood Hits	176
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

COFA1_MOUSE
θ value	5.27518 (rank : 814)	NC score	0.046994 (rank : 959)
Query Neighborhood Hits	997	Target Neighborhood Hits	305	Shared Neighborhood Hits	125
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

CRK_HUMAN
θ value	5.27518 (rank : 815)	NC score	0.035968 (rank : 1045)
Query Neighborhood Hits	997	Target Neighborhood Hits	308	Shared Neighborhood Hits	64
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

DC1L2_MOUSE
θ value	5.27518 (rank : 816)	NC score	0.013679 (rank : 1214)
Query Neighborhood Hits	997	Target Neighborhood Hits	173	Shared Neighborhood Hits	59
SwissProt Accessions	Q6PDL0	Gene names	Dync1li2, Dncli2, Dnclic2
Domain Architecture	No domain graphic available
Description	Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic).

DOS_HUMAN
θ value	5.27518 (rank : 817)	NC score	0.021166 (rank : 1151)
Query Neighborhood Hits	997	Target Neighborhood Hits	68	Shared Neighborhood Hits	19
SwissProt Accessions	Q8N350, O43385	Gene names	DOS, C19orf26
Domain Architecture	No domain graphic available
Description	Protein Dos.

DUET_HUMAN
θ value	5.27518 (rank : 818)	NC score	0.029135 (rank : 1090)
Query Neighborhood Hits	997	Target Neighborhood Hits	1220	Shared Neighborhood Hits	124
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

FA84B_HUMAN
θ value	5.27518 (rank : 819)	NC score	0.005904 (rank : 1283)
Query Neighborhood Hits	997	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q96KN1	Gene names	FAM84B, NSE2
Domain Architecture	No domain graphic available
Description	Protein FAM84B (Protein NSE2) (Breast cancer membrane protein 101).

FGD1_MOUSE
θ value	5.27518 (rank : 820)	NC score	0.030273 (rank : 1083)
Query Neighborhood Hits	997	Target Neighborhood Hits	387	Shared Neighborhood Hits	136
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FMN1A_MOUSE
θ value	5.27518 (rank : 821)	NC score	0.072682 (rank : 556)
Query Neighborhood Hits	997	Target Neighborhood Hits	423	Shared Neighborhood Hits	164
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

FOXJ3_HUMAN
θ value	5.27518 (rank : 822)	NC score	0.004179 (rank : 1296)
Query Neighborhood Hits	997	Target Neighborhood Hits	177	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UPW0, Q9NSS7	Gene names	FOXJ3, KIAA1041
Domain Architecture
Description	Forkhead box protein J3.

FOXK2_HUMAN
θ value	5.27518 (rank : 823)	NC score	0.009489 (rank : 1245)
Query Neighborhood Hits	997	Target Neighborhood Hits	190	Shared Neighborhood Hits	50
SwissProt Accessions	Q01167, Q13622, Q13623, Q13624	Gene names	FOXK2, ILF, ILF1
Domain Architecture
Description	Forkhead box protein K2 (Interleukin enhancer-binding factor 1) (Cellular transcription factor ILF-1).

HCN2_HUMAN
θ value	5.27518 (rank : 824)	NC score	0.045226 (rank : 972)
Query Neighborhood Hits	997	Target Neighborhood Hits	369	Shared Neighborhood Hits	175
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HXB9_MOUSE
θ value	5.27518 (rank : 825)	NC score	-0.006367 (rank : 1326)
Query Neighborhood Hits	997	Target Neighborhood Hits	344	Shared Neighborhood Hits	20
SwissProt Accessions	P20615	Gene names	Hoxb9, Hox-2.5, Hoxb-9
Domain Architecture
Description	Homeobox protein Hox-B9 (Hox-2.5).

JIP2_HUMAN
θ value	5.27518 (rank : 826)	NC score	0.049937 (rank : 938)
Query Neighborhood Hits	997	Target Neighborhood Hits	288	Shared Neighborhood Hits	112
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

K1849_HUMAN
θ value	5.27518 (rank : 827)	NC score	0.007890 (rank : 1261)
Query Neighborhood Hits	997	Target Neighborhood Hits	220	Shared Neighborhood Hits	35
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

K1949_MOUSE
θ value	5.27518 (rank : 828)	NC score	0.033640 (rank : 1059)
Query Neighborhood Hits	997	Target Neighborhood Hits	134	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BQ30, Q3UDS6, Q8CEY9, Q8R3D8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1949 homolog.

MAK_MOUSE
θ value	5.27518 (rank : 829)	NC score	0.028708 (rank : 1096)
Query Neighborhood Hits	997	Target Neighborhood Hits	873	Shared Neighborhood Hits	89
SwissProt Accessions	Q04859	Gene names	Mak, Rck
Domain Architecture
Description	Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male germ cell- associated kinase) (Protein kinase RCK).

MARK3_HUMAN
θ value	5.27518 (rank : 830)	NC score	0.035133 (rank : 1052)
Query Neighborhood Hits	997	Target Neighborhood Hits	893	Shared Neighborhood Hits	91
SwissProt Accessions	P27448, O60219, Q8TB41, Q8WX83, Q96RG1, Q9UMY9, Q9UN34	Gene names	MARK3, CTAK1
Domain Architecture
Description	MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (Cdc25C- associated protein kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein kinase p78) (Ser/Thr protein kinase PAR-1) (Protein kinase STK10).

MAST2_HUMAN
θ value	5.27518 (rank : 831)	NC score	0.035567 (rank : 1048)
Query Neighborhood Hits	997	Target Neighborhood Hits	1189	Shared Neighborhood Hits	169
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

NCOA1_MOUSE
θ value	5.27518 (rank : 832)	NC score	0.008808 (rank : 1250)
Query Neighborhood Hits	997	Target Neighborhood Hits	196	Shared Neighborhood Hits	51
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

NOS3_HUMAN
θ value	5.27518 (rank : 833)	NC score	0.007556 (rank : 1265)
Query Neighborhood Hits	997	Target Neighborhood Hits	59	Shared Neighborhood Hits	23
SwissProt Accessions	P29474, Q13662, Q14251, Q14434	Gene names	NOS3
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).

NOS3_MOUSE
θ value	5.27518 (rank : 834)	NC score	0.005567 (rank : 1288)
Query Neighborhood Hits	997	Target Neighborhood Hits	63	Shared Neighborhood Hits	23
SwissProt Accessions	P70313, O55056	Gene names	Nos3, Ecnos
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).

NR4A3_HUMAN
θ value	5.27518 (rank : 835)	NC score	0.008151 (rank : 1257)
Query Neighborhood Hits	997	Target Neighborhood Hits	131	Shared Neighborhood Hits	20
SwissProt Accessions	Q92570, Q12935, Q14979, Q16420, Q4VXA9, Q9UEK2, Q9UEK3	Gene names	NR4A3, CHN, CSMF, MINOR, NOR1, TEC
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Nuclear hormone receptor NOR-1) (Neuron-derived orphan receptor 1) (Mitogen-induced nuclear orphan receptor).

PER3_HUMAN
θ value	5.27518 (rank : 836)	NC score	0.048195 (rank : 953)
Query Neighborhood Hits	997	Target Neighborhood Hits	479	Shared Neighborhood Hits	150
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PTN22_MOUSE
θ value	5.27518 (rank : 837)	NC score	0.006289 (rank : 1279)
Query Neighborhood Hits	997	Target Neighborhood Hits	179	Shared Neighborhood Hits	44
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

RASF7_MOUSE
θ value	5.27518 (rank : 838)	NC score	0.023354 (rank : 1137)
Query Neighborhood Hits	997	Target Neighborhood Hits	136	Shared Neighborhood Hits	41
SwissProt Accessions	Q9DD19	Gene names	Rassf7
Domain Architecture
Description	Ras association domain-containing protein 7.

REXO4_MOUSE
θ value	5.27518 (rank : 839)	NC score	0.006819 (rank : 1272)
Query Neighborhood Hits	997	Target Neighborhood Hits	42	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PAQ4, Q3UU17, Q8C524	Gene names	Rexo4, Gm111, Pmc2, Xpmc2h
Domain Architecture	No domain graphic available
Description	RNA exonuclease 4 (EC 3.1.-.-) (Exonuclease XPMC2) (Prevents mitotic catastrophe 2 protein homolog).

RP1L1_MOUSE
θ value	5.27518 (rank : 840)	NC score	0.010281 (rank : 1239)
Query Neighborhood Hits	997	Target Neighborhood Hits	170	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

RREB1_HUMAN
θ value	5.27518 (rank : 841)	NC score	0.002613 (rank : 1310)
Query Neighborhood Hits	997	Target Neighborhood Hits	879	Shared Neighborhood Hits	97
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

S2A4R_HUMAN
θ value	5.27518 (rank : 842)	NC score	0.019414 (rank : 1167)
Query Neighborhood Hits	997	Target Neighborhood Hits	54	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NR83, Q6F6I6, Q6F6I7, Q6GTK5, Q8TAH5, Q8WVW7, Q96QD3, Q9BV85	Gene names	SLC2A4RG, HDBP1
Domain Architecture	No domain graphic available
Description	SLC2A4 regulator (GLUT4 enhancer factor) (GEF) (Huntington disease gene regulatory region-binding protein 1) (HDBP-1).

SH3K1_HUMAN
θ value	5.27518 (rank : 843)	NC score	0.057862 (rank : 774)
Query Neighborhood Hits	997	Target Neighborhood Hits	341	Shared Neighborhood Hits	92
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SH3K1_MOUSE
θ value	5.27518 (rank : 844)	NC score	0.055124 (rank : 817)
Query Neighborhood Hits	997	Target Neighborhood Hits	332	Shared Neighborhood Hits	86
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

SN1L1_MOUSE
θ value	5.27518 (rank : 845)	NC score	0.038186 (rank : 1022)
Query Neighborhood Hits	997	Target Neighborhood Hits	895	Shared Neighborhood Hits	93
SwissProt Accessions	Q60670	Gene names	Snf1lk, Msk
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1- like kinase).

SYNP2_HUMAN
θ value	5.27518 (rank : 846)	NC score	0.026399 (rank : 1120)
Query Neighborhood Hits	997	Target Neighborhood Hits	323	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

TACC2_MOUSE
θ value	5.27518 (rank : 847)	NC score	0.054766 (rank : 823)
Query Neighborhood Hits	997	Target Neighborhood Hits	774	Shared Neighborhood Hits	134
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TAF9B_MOUSE
θ value	5.27518 (rank : 848)	NC score	0.006490 (rank : 1277)
Query Neighborhood Hits	997	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	Q6NZA9, Q3UXZ3, Q3V2M4, Q80WW6	Gene names	Taf9b, Taf9l
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 9B (Transcription initiation factor TFIID subunit 9-like protein) (Transcription- associated factor TAFII31L).

TBX18_HUMAN
θ value	5.27518 (rank : 849)	NC score	0.001864 (rank : 1312)
Query Neighborhood Hits	997	Target Neighborhood Hits	148	Shared Neighborhood Hits	38
SwissProt Accessions	O95935, Q7Z6U4, Q9UJI6	Gene names	TBX18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

TM108_MOUSE
θ value	5.27518 (rank : 850)	NC score	0.076955 (rank : 523)
Query Neighborhood Hits	997	Target Neighborhood Hits	336	Shared Neighborhood Hits	122
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TPP2_MOUSE
θ value	5.27518 (rank : 851)	NC score	0.012728 (rank : 1220)
Query Neighborhood Hits	997	Target Neighborhood Hits	24	Shared Neighborhood Hits	8
SwissProt Accessions	Q64514	Gene names	Tpp2
Domain Architecture
Description	Tripeptidyl-peptidase 2 (EC 3.4.14.10) (Tripeptidyl-peptidase II) (TPP-II) (Tripeptidyl aminopeptidase).

TSC1_HUMAN
θ value	5.27518 (rank : 852)	NC score	0.026661 (rank : 1117)
Query Neighborhood Hits	997	Target Neighborhood Hits	765	Shared Neighborhood Hits	89
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

TSNA1_HUMAN
θ value	5.27518 (rank : 853)	NC score	0.011411 (rank : 1233)
Query Neighborhood Hits	997	Target Neighborhood Hits	178	Shared Neighborhood Hits	37
SwissProt Accessions	Q96NA8	Gene names	TSNARE1
Domain Architecture	No domain graphic available
Description	t-SNARE domain-containing protein 1.

UBP43_HUMAN
θ value	5.27518 (rank : 854)	NC score	0.006229 (rank : 1280)
Query Neighborhood Hits	997	Target Neighborhood Hits	144	Shared Neighborhood Hits	34
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

VAV3_HUMAN
θ value	5.27518 (rank : 855)	NC score	0.013531 (rank : 1215)
Query Neighborhood Hits	997	Target Neighborhood Hits	398	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

ZEP1_MOUSE
θ value	5.27518 (rank : 856)	NC score	0.007045 (rank : 1269)
Query Neighborhood Hits	997	Target Neighborhood Hits	1063	Shared Neighborhood Hits	130
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

ZN213_HUMAN
θ value	5.27518 (rank : 857)	NC score	-0.013495 (rank : 1339)
Query Neighborhood Hits	997	Target Neighborhood Hits	755	Shared Neighborhood Hits	41
SwissProt Accessions	O14771, Q96IS1	Gene names	ZNF213
Domain Architecture
Description	Zinc finger protein 213 (Putative transcription factor CR53).

ZN447_HUMAN
θ value	5.27518 (rank : 858)	NC score	-0.001812 (rank : 1319)
Query Neighborhood Hits	997	Target Neighborhood Hits	899	Shared Neighborhood Hits	87
SwissProt Accessions	Q8TBC5, Q9BRK7, Q9H9A0	Gene names	ZNF447
Domain Architecture	No domain graphic available
Description	Zinc finger protein 447.

ZSCA5_HUMAN
θ value	5.27518 (rank : 859)	NC score	-0.010269 (rank : 1333)
Query Neighborhood Hits	997	Target Neighborhood Hits	862	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BUG6	Gene names	ZSCAN5, ZNF495
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 5 (Zinc finger protein 495).

AAKG2_HUMAN
θ value	6.88961 (rank : 860)	NC score	0.004177 (rank : 1297)
Query Neighborhood Hits	997	Target Neighborhood Hits	56	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UGJ0, Q53Y07, Q6NUI0, Q75MP4, Q9NUZ9, Q9UDN8, Q9ULX8	Gene names	PRKAG2
Domain Architecture
Description	5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma-2 chain) (AMPK gamma2) (H91620p).

AIRE_MOUSE
θ value	6.88961 (rank : 861)	NC score	0.019379 (rank : 1168)
Query Neighborhood Hits	997	Target Neighborhood Hits	196	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

ANXA7_HUMAN
θ value	6.88961 (rank : 862)	NC score	0.013168 (rank : 1218)
Query Neighborhood Hits	997	Target Neighborhood Hits	168	Shared Neighborhood Hits	72
SwissProt Accessions	P20073	Gene names	ANXA7, ANX7, SNX
Domain Architecture
Description	Annexin A7 (Annexin VII) (Synexin).

ARHG1_MOUSE
θ value	6.88961 (rank : 863)	NC score	0.017612 (rank : 1182)
Query Neighborhood Hits	997	Target Neighborhood Hits	266	Shared Neighborhood Hits	108
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

ARHGG_MOUSE
θ value	6.88961 (rank : 864)	NC score	0.006776 (rank : 1273)
Query Neighborhood Hits	997	Target Neighborhood Hits	152	Shared Neighborhood Hits	36
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

BUB1B_HUMAN
θ value	6.88961 (rank : 865)	NC score	0.014257 (rank : 1209)
Query Neighborhood Hits	997	Target Neighborhood Hits	208	Shared Neighborhood Hits	27
SwissProt Accessions	O60566, O60501, O60627, O60758, O75389, Q96KM4	Gene names	BUB1B, BUBR1, MAD3L
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (hBUBR1) (MAD3/BUB1-related protein kinase) (Mitotic checkpoint kinase MAD3L) (SSK1).

BUB1B_MOUSE
θ value	6.88961 (rank : 866)	NC score	0.012055 (rank : 1228)
Query Neighborhood Hits	997	Target Neighborhood Hits	202	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Z1S0	Gene names	Bub1b, Mad3l
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (Mitotic checkpoint kinase MAD3L).

CEND1_MOUSE
θ value	6.88961 (rank : 867)	NC score	0.071942 (rank : 565)
Query Neighborhood Hits	997	Target Neighborhood Hits	260	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CK024_MOUSE
θ value	6.88961 (rank : 868)	NC score	0.063162 (rank : 661)
Query Neighborhood Hits	997	Target Neighborhood Hits	307	Shared Neighborhood Hits	96
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

CNOT3_HUMAN
θ value	6.88961 (rank : 869)	NC score	0.071578 (rank : 568)
Query Neighborhood Hits	997	Target Neighborhood Hits	425	Shared Neighborhood Hits	117
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CO039_MOUSE
θ value	6.88961 (rank : 870)	NC score	0.077031 (rank : 522)
Query Neighborhood Hits	997	Target Neighborhood Hits	445	Shared Neighborhood Hits	176
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

CO5A3_HUMAN
θ value	6.88961 (rank : 871)	NC score	0.050139 (rank : 930)
Query Neighborhood Hits	997	Target Neighborhood Hits	433	Shared Neighborhood Hits	154
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

CO6A2_HUMAN
θ value	6.88961 (rank : 872)	NC score	0.033312 (rank : 1064)
Query Neighborhood Hits	997	Target Neighborhood Hits	249	Shared Neighborhood Hits	86
SwissProt Accessions	P12110, Q13909, Q13910, Q13911, Q14049, Q16259, Q16597, Q9UML3	Gene names	COL6A2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

CO6A2_MOUSE
θ value	6.88961 (rank : 873)	NC score	0.031903 (rank : 1072)
Query Neighborhood Hits	997	Target Neighborhood Hits	260	Shared Neighborhood Hits	84
SwissProt Accessions	Q02788, Q05505	Gene names	Col6a2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

CONA1_MOUSE
θ value	6.88961 (rank : 874)	NC score	0.045788 (rank : 965)
Query Neighborhood Hits	997	Target Neighborhood Hits	254	Shared Neighborhood Hits	106
SwissProt Accessions	Q8K4G2, Q5SUQ0	Gene names	Col23a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

CRK_MOUSE
θ value	6.88961 (rank : 875)	NC score	0.034192 (rank : 1057)
Query Neighborhood Hits	997	Target Neighborhood Hits	314	Shared Neighborhood Hits	67
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRTC1_HUMAN
θ value	6.88961 (rank : 876)	NC score	0.081350 (rank : 503)
Query Neighborhood Hits	997	Target Neighborhood Hits	319	Shared Neighborhood Hits	158
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

DIAP1_HUMAN
θ value	6.88961 (rank : 877)	NC score	0.071293 (rank : 573)
Query Neighborhood Hits	997	Target Neighborhood Hits	784	Shared Neighborhood Hits	189
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

DOCK4_MOUSE
θ value	6.88961 (rank : 878)	NC score	0.019475 (rank : 1164)
Query Neighborhood Hits	997	Target Neighborhood Hits	210	Shared Neighborhood Hits	68
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DOK2_MOUSE
θ value	6.88961 (rank : 879)	NC score	0.020929 (rank : 1157)
Query Neighborhood Hits	997	Target Neighborhood Hits	244	Shared Neighborhood Hits	84
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

DYN2_HUMAN
θ value	6.88961 (rank : 880)	NC score	0.021044 (rank : 1153)
Query Neighborhood Hits	997	Target Neighborhood Hits	112	Shared Neighborhood Hits	42
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

DYN3_HUMAN
θ value	6.88961 (rank : 881)	NC score	0.026619 (rank : 1118)
Query Neighborhood Hits	997	Target Neighborhood Hits	158	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

EGR4_HUMAN
θ value	6.88961 (rank : 882)	NC score	-0.005246 (rank : 1324)
Query Neighborhood Hits	997	Target Neighborhood Hits	939	Shared Neighborhood Hits	129
SwissProt Accessions	Q05215	Gene names	EGR4
Domain Architecture
Description	Early growth response protein 4 (EGR-4) (AT133).

ELL_HUMAN
θ value	6.88961 (rank : 883)	NC score	0.009857 (rank : 1243)
Query Neighborhood Hits	997	Target Neighborhood Hits	183	Shared Neighborhood Hits	55
SwissProt Accessions	P55199	Gene names	ELL, C19orf17
Domain Architecture
Description	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein).

EP400_HUMAN
θ value	6.88961 (rank : 884)	NC score	0.048810 (rank : 946)
Query Neighborhood Hits	997	Target Neighborhood Hits	556	Shared Neighborhood Hits	188
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

GA2L1_MOUSE
θ value	6.88961 (rank : 885)	NC score	0.035975 (rank : 1044)
Query Neighborhood Hits	997	Target Neighborhood Hits	114	Shared Neighborhood Hits	52
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

GAK8_HUMAN
θ value	6.88961 (rank : 886)	NC score	0.021551 (rank : 1149)
Query Neighborhood Hits	997	Target Neighborhood Hits	145	Shared Neighborhood Hits	57
SwissProt Accessions	Q9HDB9	Gene names	ERVK5
Domain Architecture	No domain graphic available
Description	HERV-K_3q12.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(II) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GRAP_HUMAN
θ value	6.88961 (rank : 887)	NC score	0.039342 (rank : 1011)
Query Neighborhood Hits	997	Target Neighborhood Hits	307	Shared Neighborhood Hits	70
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

HCN4_MOUSE
θ value	6.88961 (rank : 888)	NC score	0.036583 (rank : 1038)
Query Neighborhood Hits	997	Target Neighborhood Hits	284	Shared Neighborhood Hits	125
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

IF39_HUMAN
θ value	6.88961 (rank : 889)	NC score	0.029232 (rank : 1089)
Query Neighborhood Hits	997	Target Neighborhood Hits	187	Shared Neighborhood Hits	44
SwissProt Accessions	P55884, Q9UMF9	Gene names	EIF3S9
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) (Prt1 homolog) (hPrt1).

ITSN1_HUMAN
θ value	6.88961 (rank : 890)	NC score	0.039948 (rank : 1006)
Query Neighborhood Hits	997	Target Neighborhood Hits	1757	Shared Neighborhood Hits	213
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

K0056_HUMAN
θ value	6.88961 (rank : 891)	NC score	0.006981 (rank : 1270)
Query Neighborhood Hits	997	Target Neighborhood Hits	107	Shared Neighborhood Hits	22
SwissProt Accessions	P42695	Gene names	KIAA0056
Domain Architecture	No domain graphic available
Description	Protein KIAA0056.

KI67_HUMAN
θ value	6.88961 (rank : 892)	NC score	0.064761 (rank : 640)
Query Neighborhood Hits	997	Target Neighborhood Hits	581	Shared Neighborhood Hits	108
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

LATS2_HUMAN
θ value	6.88961 (rank : 893)	NC score	0.024083 (rank : 1131)
Query Neighborhood Hits	997	Target Neighborhood Hits	884	Shared Neighborhood Hits	104
SwissProt Accessions	Q9NRM7, Q9P2X1	Gene names	LATS2, KPM
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) (Warts-like kinase).

LIPA3_MOUSE
θ value	6.88961 (rank : 894)	NC score	0.028371 (rank : 1100)
Query Neighborhood Hits	997	Target Neighborhood Hits	636	Shared Neighborhood Hits	72
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

MAGC3_HUMAN
θ value	6.88961 (rank : 895)	NC score	0.008093 (rank : 1258)
Query Neighborhood Hits	997	Target Neighborhood Hits	71	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TD91, Q5JZ43, Q9BZ80	Gene names	MAGEC3, HCA2
Domain Architecture
Description	Melanoma-associated antigen C3 (MAGE-C3 antigen) (Hepatocellular carcinoma-associated antigen 2).

MUCDL_MOUSE
θ value	6.88961 (rank : 896)	NC score	0.052550 (rank : 861)
Query Neighborhood Hits	997	Target Neighborhood Hits	461	Shared Neighborhood Hits	132
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MYBPH_HUMAN
θ value	6.88961 (rank : 897)	NC score	0.006371 (rank : 1278)
Query Neighborhood Hits	997	Target Neighborhood Hits	256	Shared Neighborhood Hits	36
SwissProt Accessions	Q13203, Q16886, Q86YC5	Gene names	MYBPH
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

NDE1_HUMAN
θ value	6.88961 (rank : 898)	NC score	0.022128 (rank : 1146)
Query Neighborhood Hits	997	Target Neighborhood Hits	823	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

NFH_HUMAN
θ value	6.88961 (rank : 899)	NC score	0.051877 (rank : 880)
Query Neighborhood Hits	997	Target Neighborhood Hits	1242	Shared Neighborhood Hits	189
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

OBF1_HUMAN
θ value	6.88961 (rank : 900)	NC score	0.038805 (rank : 1014)
Query Neighborhood Hits	997	Target Neighborhood Hits	203	Shared Neighborhood Hits	75
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

PER2_HUMAN
θ value	6.88961 (rank : 901)	NC score	0.019206 (rank : 1170)
Query Neighborhood Hits	997	Target Neighborhood Hits	170	Shared Neighborhood Hits	49
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

PHLB1_MOUSE
θ value	6.88961 (rank : 902)	NC score	0.043906 (rank : 981)
Query Neighborhood Hits	997	Target Neighborhood Hits	678	Shared Neighborhood Hits	134
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PTPRN_MOUSE
θ value	6.88961 (rank : 903)	NC score	0.002835 (rank : 1308)
Query Neighborhood Hits	997	Target Neighborhood Hits	240	Shared Neighborhood Hits	68
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

SRRM2_MOUSE
θ value	6.88961 (rank : 904)	NC score	0.123694 (rank : 350)
Query Neighborhood Hits	997	Target Neighborhood Hits	1470	Shared Neighborhood Hits	329
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

STAM2_MOUSE
θ value	6.88961 (rank : 905)	NC score	0.039400 (rank : 1009)
Query Neighborhood Hits	997	Target Neighborhood Hits	285	Shared Neighborhood Hits	62
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

SYN2_MOUSE
θ value	6.88961 (rank : 906)	NC score	0.045327 (rank : 971)
Query Neighborhood Hits	997	Target Neighborhood Hits	183	Shared Neighborhood Hits	94
SwissProt Accessions	Q64332, Q6NZR0, Q9QWV7	Gene names	Syn2
Domain Architecture	No domain graphic available
Description	Synapsin-2 (Synapsin II).

SYNG_MOUSE
θ value	6.88961 (rank : 907)	NC score	0.020974 (rank : 1154)
Query Neighborhood Hits	997	Target Neighborhood Hits	206	Shared Neighborhood Hits	56
SwissProt Accessions	Q5SV85, Q5SV84, Q6PHT6	Gene names	Ap1gbp1, Syng
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

TAF4_HUMAN
θ value	6.88961 (rank : 908)	NC score	0.147114 (rank : 320)
Query Neighborhood Hits	997	Target Neighborhood Hits	687	Shared Neighborhood Hits	238
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TOPB1_MOUSE
θ value	6.88961 (rank : 909)	NC score	0.017134 (rank : 1183)
Query Neighborhood Hits	997	Target Neighborhood Hits	89	Shared Neighborhood Hits	30
SwissProt Accessions	Q6ZQF0, Q6P6P0, Q80Y33, Q8BUI0, Q8BUK1, Q8R348, Q91VX3, Q922X8	Gene names	Topbp1, Kiaa0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase II-binding protein 1 (DNA topoisomerase IIbeta- binding protein 1) (TopBP1).

TP53B_MOUSE
θ value	6.88961 (rank : 910)	NC score	0.060668 (rank : 705)
Query Neighborhood Hits	997	Target Neighborhood Hits	644	Shared Neighborhood Hits	147
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TRPC3_HUMAN
θ value	6.88961 (rank : 911)	NC score	0.086300 (rank : 481)
Query Neighborhood Hits	997	Target Neighborhood Hits	137	Shared Neighborhood Hits	81
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

TSH3_MOUSE
θ value	6.88961 (rank : 912)	NC score	0.002881 (rank : 1307)
Query Neighborhood Hits	997	Target Neighborhood Hits	590	Shared Neighborhood Hits	46
SwissProt Accessions	Q8CGV9, Q5DTX4	Gene names	Tshz3, Kiaa1474, Tsh3, Zfp537, Znf537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

UBP42_HUMAN
θ value	6.88961 (rank : 913)	NC score	0.029016 (rank : 1091)
Query Neighborhood Hits	997	Target Neighborhood Hits	445	Shared Neighborhood Hits	138
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UROL1_MOUSE
θ value	6.88961 (rank : 914)	NC score	0.028539 (rank : 1098)
Query Neighborhood Hits	997	Target Neighborhood Hits	235	Shared Neighborhood Hits	39
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

VASP_MOUSE
θ value	6.88961 (rank : 915)	NC score	0.068278 (rank : 595)
Query Neighborhood Hits	997	Target Neighborhood Hits	195	Shared Neighborhood Hits	91
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

WASP_HUMAN
θ value	6.88961 (rank : 916)	NC score	0.089555 (rank : 466)
Query Neighborhood Hits	997	Target Neighborhood Hits	195	Shared Neighborhood Hits	110
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

YLPM1_HUMAN
θ value	6.88961 (rank : 917)	NC score	0.111532 (rank : 375)
Query Neighborhood Hits	997	Target Neighborhood Hits	670	Shared Neighborhood Hits	218
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

ZBTB3_HUMAN
θ value	6.88961 (rank : 918)	NC score	-0.004485 (rank : 1323)
Query Neighborhood Hits	997	Target Neighborhood Hits	910	Shared Neighborhood Hits	74
SwissProt Accessions	Q9H5J0	Gene names	ZBTB3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

ZN598_HUMAN
θ value	6.88961 (rank : 919)	NC score	0.049813 (rank : 940)
Query Neighborhood Hits	997	Target Neighborhood Hits	339	Shared Neighborhood Hits	95
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

3BP1_MOUSE
θ value	8.99809 (rank : 920)	NC score	0.048243 (rank : 951)
Query Neighborhood Hits	997	Target Neighborhood Hits	238	Shared Neighborhood Hits	104
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

AAK1_HUMAN
θ value	8.99809 (rank : 921)	NC score	0.043368 (rank : 985)
Query Neighborhood Hits	997	Target Neighborhood Hits	1077	Shared Neighborhood Hits	199
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

ABRA_HUMAN
θ value	8.99809 (rank : 922)	NC score	0.007570 (rank : 1264)
Query Neighborhood Hits	997	Target Neighborhood Hits	52	Shared Neighborhood Hits	20
SwissProt Accessions	Q8N0Z2	Gene names	ABRA
Domain Architecture	No domain graphic available
Description	Actin-binding Rho-activating protein (Striated muscle activator of Rho-dependent signaling) (STARS).

ANKR9_MOUSE
θ value	8.99809 (rank : 923)	NC score	0.257839 (rank : 283)
Query Neighborhood Hits	997	Target Neighborhood Hits	120	Shared Neighborhood Hits	116
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ANR40_HUMAN
θ value	8.99809 (rank : 924)	NC score	0.534306 (rank : 217)
Query Neighborhood Hits	997	Target Neighborhood Hits	224	Shared Neighborhood Hits	213
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANR40_MOUSE
θ value	8.99809 (rank : 925)	NC score	0.531839 (rank : 219)
Query Neighborhood Hits	997	Target Neighborhood Hits	228	Shared Neighborhood Hits	214
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ARHG6_HUMAN
θ value	8.99809 (rank : 926)	NC score	0.029882 (rank : 1084)
Query Neighborhood Hits	997	Target Neighborhood Hits	376	Shared Neighborhood Hits	68
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

ARI1A_HUMAN
θ value	8.99809 (rank : 927)	NC score	0.096428 (rank : 438)
Query Neighborhood Hits	997	Target Neighborhood Hits	787	Shared Neighborhood Hits	251
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

ATL2_MOUSE
θ value	8.99809 (rank : 928)	NC score	-0.001172 (rank : 1318)
Query Neighborhood Hits	997	Target Neighborhood Hits	137	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

AUTS2_HUMAN
θ value	8.99809 (rank : 929)	NC score	0.066551 (rank : 610)
Query Neighborhood Hits	997	Target Neighborhood Hits	342	Shared Neighborhood Hits	130
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

BAG3_HUMAN
θ value	8.99809 (rank : 930)	NC score	0.073998 (rank : 546)
Query Neighborhood Hits	997	Target Neighborhood Hits	314	Shared Neighborhood Hits	138
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

BTBD2_HUMAN
θ value	8.99809 (rank : 931)	NC score	0.006751 (rank : 1274)
Query Neighborhood Hits	997	Target Neighborhood Hits	161	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BX70, O60418, O75248, Q7Z5W0, Q96SX8, Q9NPS1, Q9NX81	Gene names	BTBD2
Domain Architecture
Description	BTB/POZ domain-containing protein 2.

CDAN1_HUMAN
θ value	8.99809 (rank : 932)	NC score	0.039521 (rank : 1008)
Query Neighborhood Hits	997	Target Neighborhood Hits	92	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IWY9, Q7Z7L5, Q969N3	Gene names	CDAN1
Domain Architecture	No domain graphic available
Description	Codanin-1.

CDC20_HUMAN
θ value	8.99809 (rank : 933)	NC score	-0.003872 (rank : 1321)
Query Neighborhood Hits	997	Target Neighborhood Hits	329	Shared Neighborhood Hits	29
SwissProt Accessions	Q12834, Q9BW56, Q9UQI9	Gene names	CDC20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC).

CO4A3_HUMAN
θ value	8.99809 (rank : 934)	NC score	0.052245 (rank : 869)
Query Neighborhood Hits	997	Target Neighborhood Hits	421	Shared Neighborhood Hits	149
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

CO8A1_HUMAN
θ value	8.99809 (rank : 935)	NC score	0.048769 (rank : 948)
Query Neighborhood Hits	997	Target Neighborhood Hits	288	Shared Neighborhood Hits	121
SwissProt Accessions	P27658, Q96D07	Gene names	COL8A1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor (Endothelial collagen).

CO8A1_MOUSE
θ value	8.99809 (rank : 936)	NC score	0.048261 (rank : 950)
Query Neighborhood Hits	997	Target Neighborhood Hits	251	Shared Neighborhood Hits	108
SwissProt Accessions	Q00780, Q9D2V4	Gene names	Col8a1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor.

CONA1_HUMAN
θ value	8.99809 (rank : 937)	NC score	0.047268 (rank : 957)
Query Neighborhood Hits	997	Target Neighborhood Hits	281	Shared Neighborhood Hits	106
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

CP007_MOUSE
θ value	8.99809 (rank : 938)	NC score	0.015175 (rank : 1198)
Query Neighborhood Hits	997	Target Neighborhood Hits	231	Shared Neighborhood Hits	51
SwissProt Accessions	Q8C190, Q6PFD1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 homolog (5-day ovary-specific transcript 1 protein).

CS007_HUMAN
θ value	8.99809 (rank : 939)	NC score	0.076188 (rank : 528)
Query Neighborhood Hits	997	Target Neighborhood Hits	401	Shared Neighborhood Hits	148
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

CUTL1_HUMAN
θ value	8.99809 (rank : 940)	NC score	0.038325 (rank : 1020)
Query Neighborhood Hits	997	Target Neighborhood Hits	1574	Shared Neighborhood Hits	175
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

DAF1_MOUSE
θ value	8.99809 (rank : 941)	NC score	0.008706 (rank : 1252)
Query Neighborhood Hits	997	Target Neighborhood Hits	204	Shared Neighborhood Hits	48
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

DDX51_HUMAN
θ value	8.99809 (rank : 942)	NC score	0.012241 (rank : 1225)
Query Neighborhood Hits	997	Target Neighborhood Hits	332	Shared Neighborhood Hits	71
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DGCR8_MOUSE
θ value	8.99809 (rank : 943)	NC score	0.007891 (rank : 1260)
Query Neighborhood Hits	997	Target Neighborhood Hits	70	Shared Neighborhood Hits	9
SwissProt Accessions	Q9EQM6	Gene names	Dgcr8
Domain Architecture	No domain graphic available
Description	DGCR8 protein (DiGeorge syndrome critical region 8 homolog) (Gy1).

DIAP1_MOUSE
θ value	8.99809 (rank : 944)	NC score	0.069330 (rank : 583)
Query Neighborhood Hits	997	Target Neighborhood Hits	839	Shared Neighborhood Hits	164
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

DPOLL_MOUSE
θ value	8.99809 (rank : 945)	NC score	0.009495 (rank : 1244)
Query Neighborhood Hits	997	Target Neighborhood Hits	71	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QXE2, Q9CTJ1	Gene names	Poll, Polk
Domain Architecture
Description	DNA polymerase lambda (EC 2.7.7.7) (EC 4.2.99.-) (Pol Lambda) (DNA polymerase kappa).

ERCC1_HUMAN
θ value	8.99809 (rank : 946)	NC score	0.005784 (rank : 1284)
Query Neighborhood Hits	997	Target Neighborhood Hits	34	Shared Neighborhood Hits	13
SwissProt Accessions	P07992	Gene names	ERCC1
Domain Architecture
Description	DNA excision repair protein ERCC-1.

FMN2_MOUSE
θ value	8.99809 (rank : 947)	NC score	0.070668 (rank : 579)
Query Neighborhood Hits	997	Target Neighborhood Hits	349	Shared Neighborhood Hits	138
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

FREA_HUMAN
θ value	8.99809 (rank : 948)	NC score	0.014922 (rank : 1202)
Query Neighborhood Hits	997	Target Neighborhood Hits	205	Shared Neighborhood Hits	74
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

GLUD1_MOUSE
θ value	8.99809 (rank : 949)	NC score	0.009161 (rank : 1247)
Query Neighborhood Hits	997	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CIX8	Gene names	Gluld1, Lgs
Domain Architecture	No domain graphic available
Description	Glutamate--ammonia ligase domain-containing protein 1 (Lengsin) (Lens glutamine synthase-like).

GP152_HUMAN
θ value	8.99809 (rank : 950)	NC score	0.020756 (rank : 1158)
Query Neighborhood Hits	997	Target Neighborhood Hits	636	Shared Neighborhood Hits	128
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

GRIN1_MOUSE
θ value	8.99809 (rank : 951)	NC score	0.077799 (rank : 516)
Query Neighborhood Hits	997	Target Neighborhood Hits	337	Shared Neighborhood Hits	126
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

H6ST3_MOUSE
θ value	8.99809 (rank : 952)	NC score	0.003307 (rank : 1303)
Query Neighborhood Hits	997	Target Neighborhood Hits	46	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QYK4	Gene names	Hs6st3
Domain Architecture	No domain graphic available
Description	Heparan-sulfate 6-O-sulfotransferase 3 (EC 2.8.2.-) (HS6ST-3) (mHS6ST- 3).

HGS_MOUSE
θ value	8.99809 (rank : 953)	NC score	0.040710 (rank : 1002)
Query Neighborhood Hits	997	Target Neighborhood Hits	589	Shared Neighborhood Hits	123
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HRBL_HUMAN
θ value	8.99809 (rank : 954)	NC score	0.042358 (rank : 992)
Query Neighborhood Hits	997	Target Neighborhood Hits	179	Shared Neighborhood Hits	72
SwissProt Accessions	O95081, O75429, Q96AB9, Q96GL4	Gene names	HRBL, RABR
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

HRX_HUMAN
θ value	8.99809 (rank : 955)	NC score	0.079764 (rank : 505)
Query Neighborhood Hits	997	Target Neighborhood Hits	825	Shared Neighborhood Hits	183
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

IF4B_HUMAN
θ value	8.99809 (rank : 956)	NC score	0.025845 (rank : 1123)
Query Neighborhood Hits	997	Target Neighborhood Hits	417	Shared Neighborhood Hits	107
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

INSI1_MOUSE
θ value	8.99809 (rank : 957)	NC score	0.004628 (rank : 1291)
Query Neighborhood Hits	997	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGI3, Q3UAX9	Gene names	Insig1
Domain Architecture	No domain graphic available
Description	Insulin-induced gene 1 protein (INSIG-1).

JHD3B_MOUSE
θ value	8.99809 (rank : 958)	NC score	0.015355 (rank : 1195)
Query Neighborhood Hits	997	Target Neighborhood Hits	152	Shared Neighborhood Hits	55
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

JIP1_HUMAN
θ value	8.99809 (rank : 959)	NC score	0.041373 (rank : 997)
Query Neighborhood Hits	997	Target Neighborhood Hits	271	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

JPH1_MOUSE
θ value	8.99809 (rank : 960)	NC score	0.015900 (rank : 1192)
Query Neighborhood Hits	997	Target Neighborhood Hits	120	Shared Neighborhood Hits	37
SwissProt Accessions	Q9ET80, Q9EQZ3	Gene names	Jph1, Jp1
Domain Architecture
Description	Junctophilin-1 (Junctophilin type 1) (JP-1).

LZTS2_MOUSE
θ value	8.99809 (rank : 961)	NC score	0.019204 (rank : 1171)
Query Neighborhood Hits	997	Target Neighborhood Hits	423	Shared Neighborhood Hits	64
SwissProt Accessions	Q91YU6, Q569X6	Gene names	Lzts2, Kiaa1813
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2.

MARE1_HUMAN
θ value	8.99809 (rank : 962)	NC score	0.001719 (rank : 1313)
Query Neighborhood Hits	997	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q15691	Gene names	MAPRE1
Domain Architecture
Description	Microtubule-associated protein RP/EB family member 1 (APC-binding protein EB1) (End-binding protein 1) (EB1).

MARK3_MOUSE
θ value	8.99809 (rank : 963)	NC score	0.036205 (rank : 1041)
Query Neighborhood Hits	997	Target Neighborhood Hits	919	Shared Neighborhood Hits	93
SwissProt Accessions	Q03141, Q3TM40, Q3V1U3, Q8C6G9, Q8R375, Q9JKE4	Gene names	Mark3, Emk2, Mpk10
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (MPK-10) (ELKL motif kinase 2).

MNT_MOUSE
θ value	8.99809 (rank : 964)	NC score	0.066345 (rank : 615)
Query Neighborhood Hits	997	Target Neighborhood Hits	432	Shared Neighborhood Hits	137
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MRIP_HUMAN
θ value	8.99809 (rank : 965)	NC score	0.019729 (rank : 1162)
Query Neighborhood Hits	997	Target Neighborhood Hits	578	Shared Neighborhood Hits	67
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

MYO9B_HUMAN
θ value	8.99809 (rank : 966)	NC score	0.025611 (rank : 1125)
Query Neighborhood Hits	997	Target Neighborhood Hits	641	Shared Neighborhood Hits	152
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

OXRP_HUMAN
θ value	8.99809 (rank : 967)	NC score	0.014461 (rank : 1208)
Query Neighborhood Hits	997	Target Neighborhood Hits	544	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

PIWL3_HUMAN
θ value	8.99809 (rank : 968)	NC score	0.000068 (rank : 1315)
Query Neighborhood Hits	997	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z3Z3	Gene names	PIWIL3
Domain Architecture	No domain graphic available
Description	Piwi-like protein 3.

PP1R8_MOUSE
θ value	8.99809 (rank : 969)	NC score	0.011607 (rank : 1232)
Query Neighborhood Hits	997	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R3G1, Q8C087	Gene names	Ppp1r8, Nipp1
Domain Architecture	No domain graphic available
Description	Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8).

PTCD1_HUMAN
θ value	8.99809 (rank : 970)	NC score	0.008012 (rank : 1259)
Query Neighborhood Hits	997	Target Neighborhood Hits	52	Shared Neighborhood Hits	25
SwissProt Accessions	O75127, Q66K60, Q9UDV2	Gene names	PTCD1, KIAA0632
Domain Architecture	No domain graphic available
Description	Pentatricopeptide repeat protein 1.

RBP1_HUMAN
θ value	8.99809 (rank : 971)	NC score	0.018735 (rank : 1173)
Query Neighborhood Hits	997	Target Neighborhood Hits	521	Shared Neighborhood Hits	50
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RUSC1_HUMAN
θ value	8.99809 (rank : 972)	NC score	0.028737 (rank : 1095)
Query Neighborhood Hits	997	Target Neighborhood Hits	226	Shared Neighborhood Hits	74
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

RUSC1_MOUSE
θ value	8.99809 (rank : 973)	NC score	0.024496 (rank : 1129)
Query Neighborhood Hits	997	Target Neighborhood Hits	206	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

SMAD5_MOUSE
θ value	8.99809 (rank : 974)	NC score	0.013198 (rank : 1217)
Query Neighborhood Hits	997	Target Neighborhood Hits	74	Shared Neighborhood Hits	24
SwissProt Accessions	P97454, P70341, Q810K0	Gene names	Smad5, Madh5, Msmad5
Domain Architecture
Description	Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) (mSmad5) (Dwarfin-C) (Dwf-C).

SMBP2_HUMAN
θ value	8.99809 (rank : 975)	NC score	0.006207 (rank : 1281)
Query Neighborhood Hits	997	Target Neighborhood Hits	107	Shared Neighborhood Hits	27
SwissProt Accessions	P38935, Q00443, Q14177	Gene names	IGHMBP2, SMBP2, SMUBP2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Glial factor 1) (GF-1).

SMCA2_HUMAN
θ value	8.99809 (rank : 976)	NC score	0.024556 (rank : 1128)
Query Neighborhood Hits	997	Target Neighborhood Hits	503	Shared Neighborhood Hits	136
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SNRPA_HUMAN
θ value	8.99809 (rank : 977)	NC score	0.017682 (rank : 1180)
Query Neighborhood Hits	997	Target Neighborhood Hits	128	Shared Neighborhood Hits	23
SwissProt Accessions	P09012	Gene names	SNRPA
Domain Architecture
Description	U1 small nuclear ribonucleoprotein A (U1 snRNP protein A) (U1A protein) (U1-A).

SNRPA_MOUSE
θ value	8.99809 (rank : 978)	NC score	0.018567 (rank : 1177)
Query Neighborhood Hits	997	Target Neighborhood Hits	129	Shared Neighborhood Hits	22
SwissProt Accessions	Q62189, Q52LA2	Gene names	Snrpa, Rnu1a-1
Domain Architecture
Description	U1 small nuclear ribonucleoprotein A (U1 snRNP protein A) (U1A protein) (U1-A).

SNTB2_HUMAN
θ value	8.99809 (rank : 979)	NC score	-0.000411 (rank : 1317)
Query Neighborhood Hits	997	Target Neighborhood Hits	180	Shared Neighborhood Hits	17
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SPEG_HUMAN
θ value	8.99809 (rank : 980)	NC score	0.046709 (rank : 961)
Query Neighborhood Hits	997	Target Neighborhood Hits	1762	Shared Neighborhood Hits	318
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SPRR3_HUMAN
θ value	8.99809 (rank : 981)	NC score	0.058853 (rank : 753)
Query Neighborhood Hits	997	Target Neighborhood Hits	102	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

SRRM2_HUMAN
θ value	8.99809 (rank : 982)	NC score	0.130571 (rank : 337)
Query Neighborhood Hits	997	Target Neighborhood Hits	1296	Shared Neighborhood Hits	311
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SSH1_HUMAN
θ value	8.99809 (rank : 983)	NC score	0.005778 (rank : 1285)
Query Neighborhood Hits	997	Target Neighborhood Hits	164	Shared Neighborhood Hits	46
SwissProt Accessions	Q8WYL5, Q6P6C0, Q8N9A7, Q8WYL3, Q8WYL4, Q9P2P8	Gene names	SSH1, KIAA1298, SSH1L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (hSSH-1L).

STK10_HUMAN
θ value	8.99809 (rank : 984)	NC score	0.042206 (rank : 994)
Query Neighborhood Hits	997	Target Neighborhood Hits	1921	Shared Neighborhood Hits	195
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TAF6L_MOUSE
θ value	8.99809 (rank : 985)	NC score	0.016371 (rank : 1189)
Query Neighborhood Hits	997	Target Neighborhood Hits	146	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R2K4, Q8C5T2	Gene names	Taf6l, Paf65a
Domain Architecture
Description	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65 alpha) (PAF65- alpha).

TAU_MOUSE
θ value	8.99809 (rank : 986)	NC score	0.086137 (rank : 482)
Query Neighborhood Hits	997	Target Neighborhood Hits	502	Shared Neighborhood Hits	185
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TBX21_HUMAN
θ value	8.99809 (rank : 987)	NC score	0.001930 (rank : 1311)
Query Neighborhood Hits	997	Target Neighborhood Hits	146	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UL17	Gene names	TBX21, TBET, TBLYM
Domain Architecture
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

TCGAP_MOUSE
θ value	8.99809 (rank : 988)	NC score	0.051401 (rank : 892)
Query Neighborhood Hits	997	Target Neighborhood Hits	409	Shared Neighborhood Hits	154
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCRG1_HUMAN
θ value	8.99809 (rank : 989)	NC score	0.057946 (rank : 771)
Query Neighborhood Hits	997	Target Neighborhood Hits	929	Shared Neighborhood Hits	150
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TITIN_HUMAN
θ value	8.99809 (rank : 990)	NC score	0.044042 (rank : 979)
Query Neighborhood Hits	997	Target Neighborhood Hits	2923	Shared Neighborhood Hits	353
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TPP2_HUMAN
θ value	8.99809 (rank : 991)	NC score	0.010962 (rank : 1237)
Query Neighborhood Hits	997	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	P29144	Gene names	TPP2
Domain Architecture
Description	Tripeptidyl-peptidase 2 (EC 3.4.14.10) (Tripeptidyl-peptidase II) (TPP-II) (Tripeptidyl aminopeptidase).

TRPC6_HUMAN
θ value	8.99809 (rank : 992)	NC score	0.102649 (rank : 416)
Query Neighborhood Hits	997	Target Neighborhood Hits	171	Shared Neighborhood Hits	102
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

TTLL5_HUMAN
θ value	8.99809 (rank : 993)	NC score	0.002798 (rank : 1309)
Query Neighborhood Hits	997	Target Neighborhood Hits	141	Shared Neighborhood Hits	21
SwissProt Accessions	Q6EMB2, Q9P1V5, Q9UPZ4	Gene names	TTLL5, KIAA0998, STAMP
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5 (SRC1 and TIF2-associated modulatory protein).

US6NL_HUMAN
θ value	8.99809 (rank : 994)	NC score	0.015038 (rank : 1199)
Query Neighborhood Hits	997	Target Neighborhood Hits	201	Shared Neighborhood Hits	52
SwissProt Accessions	Q92738, Q15400, Q7L0K9	Gene names	USP6NL, KIAA0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN- tre).

VAV3_MOUSE
θ value	8.99809 (rank : 995)	NC score	0.012620 (rank : 1222)
Query Neighborhood Hits	997	Target Neighborhood Hits	404	Shared Neighborhood Hits	66
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

WRIP1_MOUSE
θ value	8.99809 (rank : 996)	NC score	0.003231 (rank : 1305)
Query Neighborhood Hits	997	Target Neighborhood Hits	93	Shared Neighborhood Hits	10
SwissProt Accessions	Q91XU0, Q3TCT7, Q6PDF0, Q8BUW5, Q8BWP6, Q8BY55, Q921W3, Q9EQL3	Gene names	Wrnip1, Whip
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

ZO2_MOUSE
θ value	8.99809 (rank : 997)	NC score	0.003473 (rank : 1302)
Query Neighborhood Hits	997	Target Neighborhood Hits	296	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

AATK_HUMAN
θ value	θ > 10 (rank : 998)	NC score	0.066088 (rank : 619)
Query Neighborhood Hits	997	Target Neighborhood Hits	1243	Shared Neighborhood Hits	262
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

AATK_MOUSE
θ value	θ > 10 (rank : 999)	NC score	0.060790 (rank : 701)
Query Neighborhood Hits	997	Target Neighborhood Hits	942	Shared Neighborhood Hits	144
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

ABI2_HUMAN
θ value	θ > 10 (rank : 1000)	NC score	0.054631 (rank : 825)
Query Neighborhood Hits	997	Target Neighborhood Hits	350	Shared Neighborhood Hits	132
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ABL1_MOUSE
θ value	θ > 10 (rank : 1001)	NC score	0.065821 (rank : 627)
Query Neighborhood Hits	997	Target Neighborhood Hits	1178	Shared Neighborhood Hits	196
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL2_HUMAN
θ value	θ > 10 (rank : 1002)	NC score	0.058677 (rank : 757)
Query Neighborhood Hits	997	Target Neighborhood Hits	1045	Shared Neighborhood Hits	123
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

ABTB1_HUMAN
θ value	θ > 10 (rank : 1003)	NC score	0.231703 (rank : 286)
Query Neighborhood Hits	997	Target Neighborhood Hits	325	Shared Neighborhood Hits	164
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

ABTB1_MOUSE
θ value	θ > 10 (rank : 1004)	NC score	0.272844 (rank : 281)
Query Neighborhood Hits	997	Target Neighborhood Hits	349	Shared Neighborhood Hits	180
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

ACINU_MOUSE
θ value	θ > 10 (rank : 1005)	NC score	0.051723 (rank : 884)
Query Neighborhood Hits	997	Target Neighborhood Hits	712	Shared Neighborhood Hits	124
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ACK1_HUMAN
θ value	θ > 10 (rank : 1006)	NC score	0.075273 (rank : 535)
Query Neighborhood Hits	997	Target Neighborhood Hits	1140	Shared Neighborhood Hits	245
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

AFF1_MOUSE
θ value	θ > 10 (rank : 1007)	NC score	0.059210 (rank : 742)
Query Neighborhood Hits	997	Target Neighborhood Hits	351	Shared Neighborhood Hits	121
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

ALK_HUMAN
θ value	θ > 10 (rank : 1008)	NC score	0.058678 (rank : 756)
Query Neighborhood Hits	997	Target Neighborhood Hits	795	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

ALK_MOUSE
θ value	θ > 10 (rank : 1009)	NC score	0.059435 (rank : 736)
Query Neighborhood Hits	997	Target Neighborhood Hits	811	Shared Neighborhood Hits	86
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

AMOT_HUMAN
θ value	θ > 10 (rank : 1010)	NC score	0.052106 (rank : 874)
Query Neighborhood Hits	997	Target Neighborhood Hits	712	Shared Neighborhood Hits	137
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

AMPH_HUMAN
θ value	θ > 10 (rank : 1011)	NC score	0.051811 (rank : 883)
Query Neighborhood Hits	997	Target Neighborhood Hits	455	Shared Neighborhood Hits	122
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

AN13D_HUMAN
θ value	θ > 10 (rank : 1012)	NC score	0.054799 (rank : 821)
Query Neighborhood Hits	997	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZTN6, Q6ZVD0, Q86SU1	Gene names	ANKRD13D
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13D.

AN13D_MOUSE
θ value	θ > 10 (rank : 1013)	NC score	0.055215 (rank : 814)
Query Neighborhood Hits	997	Target Neighborhood Hits	22	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PD24	Gene names	Ankrd13d
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13D.

ANKF1_HUMAN
θ value	θ > 10 (rank : 1014)	NC score	0.126197 (rank : 346)
Query Neighborhood Hits	997	Target Neighborhood Hits	126	Shared Neighborhood Hits	78
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

ANKR9_HUMAN
θ value	θ > 10 (rank : 1015)	NC score	0.207516 (rank : 295)
Query Neighborhood Hits	997	Target Neighborhood Hits	99	Shared Neighborhood Hits	97
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ANPRA_HUMAN
θ value	θ > 10 (rank : 1016)	NC score	0.050264 (rank : 926)
Query Neighborhood Hits	997	Target Neighborhood Hits	612	Shared Neighborhood Hits	63
SwissProt Accessions	P16066, Q6P4Q3	Gene names	NPR1, ANPRA
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

ANPRA_MOUSE
θ value	θ > 10 (rank : 1017)	NC score	0.052265 (rank : 867)
Query Neighborhood Hits	997	Target Neighborhood Hits	600	Shared Neighborhood Hits	64
SwissProt Accessions	P18293	Gene names	Npr1, Npra
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

ANPRB_HUMAN
θ value	θ > 10 (rank : 1018)	NC score	0.053236 (rank : 846)
Query Neighborhood Hits	997	Target Neighborhood Hits	646	Shared Neighborhood Hits	65
SwissProt Accessions	P20594, O60871, Q9UQ50	Gene names	NPR2, ANPRB
Domain Architecture
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

ANPRB_MOUSE
θ value	θ > 10 (rank : 1019)	NC score	0.054111 (rank : 830)
Query Neighborhood Hits	997	Target Neighborhood Hits	607	Shared Neighborhood Hits	61
SwissProt Accessions	Q6VVW5, Q6VVW3, Q6VVW4, Q8CGA9	Gene names	Npr2
Domain Architecture	No domain graphic available
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

ANR45_HUMAN
θ value	θ > 10 (rank : 1020)	NC score	0.543651 (rank : 213)
Query Neighborhood Hits	997	Target Neighborhood Hits	201	Shared Neighborhood Hits	185
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ARAF_HUMAN
θ value	θ > 10 (rank : 1021)	NC score	0.056123 (rank : 802)
Query Neighborhood Hits	997	Target Neighborhood Hits	924	Shared Neighborhood Hits	98
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

ARAF_MOUSE
θ value	θ > 10 (rank : 1022)	NC score	0.055343 (rank : 812)
Query Neighborhood Hits	997	Target Neighborhood Hits	874	Shared Neighborhood Hits	82
SwissProt Accessions	P04627, Q99J44, Q9CTT5, Q9D6R6, Q9DBU7	Gene names	Araf, A-raf, Araf1
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1).

ARFG1_HUMAN
θ value	θ > 10 (rank : 1023)	NC score	0.050349 (rank : 923)
Query Neighborhood Hits	997	Target Neighborhood Hits	60	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N6T3, Q96KC4, Q96T02, Q9NSU3, Q9NVF6, Q9UIL0	Gene names	ARFGAP1, ARF1GAP
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

ARFG1_MOUSE
θ value	θ > 10 (rank : 1024)	NC score	0.051665 (rank : 885)
Query Neighborhood Hits	997	Target Neighborhood Hits	51	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EPJ9, Q3TI52, Q8BMM6, Q8BMQ7	Gene names	Arfgap1, Arf1gap
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

ARFG3_HUMAN
θ value	θ > 10 (rank : 1025)	NC score	0.051511 (rank : 888)
Query Neighborhood Hits	997	Target Neighborhood Hits	56	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ARFG3_MOUSE
θ value	θ > 10 (rank : 1026)	NC score	0.052429 (rank : 864)
Query Neighborhood Hits	997	Target Neighborhood Hits	80	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ARI1B_HUMAN
θ value	θ > 10 (rank : 1027)	NC score	0.068840 (rank : 589)
Query Neighborhood Hits	997	Target Neighborhood Hits	567	Shared Neighborhood Hits	204
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

ATX2_HUMAN
θ value	θ > 10 (rank : 1028)	NC score	0.063256 (rank : 660)
Query Neighborhood Hits	997	Target Neighborhood Hits	375	Shared Neighborhood Hits	135
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

ATX2_MOUSE
θ value	θ > 10 (rank : 1029)	NC score	0.071363 (rank : 571)
Query Neighborhood Hits	997	Target Neighborhood Hits	445	Shared Neighborhood Hits	152
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

BASP_HUMAN
θ value	θ > 10 (rank : 1030)	NC score	0.096670 (rank : 435)
Query Neighborhood Hits	997	Target Neighborhood Hits	321	Shared Neighborhood Hits	110
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BASP_MOUSE
θ value	θ > 10 (rank : 1031)	NC score	0.111695 (rank : 374)
Query Neighborhood Hits	997	Target Neighborhood Hits	260	Shared Neighborhood Hits	91
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BAT3_MOUSE
θ value	θ > 10 (rank : 1032)	NC score	0.091118 (rank : 457)
Query Neighborhood Hits	997	Target Neighborhood Hits	518	Shared Neighborhood Hits	219
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

BAT4_HUMAN
θ value	θ > 10 (rank : 1033)	NC score	0.211960 (rank : 293)
Query Neighborhood Hits	997	Target Neighborhood Hits	157	Shared Neighborhood Hits	113
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

BAT4_MOUSE
θ value	θ > 10 (rank : 1034)	NC score	0.242064 (rank : 284)
Query Neighborhood Hits	997	Target Neighborhood Hits	171	Shared Neighborhood Hits	125
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

BLK_HUMAN
θ value	θ > 10 (rank : 1035)	NC score	0.059974 (rank : 724)
Query Neighborhood Hits	997	Target Neighborhood Hits	994	Shared Neighborhood Hits	114
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BLK_MOUSE
θ value	θ > 10 (rank : 1036)	NC score	0.059078 (rank : 745)
Query Neighborhood Hits	997	Target Neighborhood Hits	992	Shared Neighborhood Hits	110
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BMPR2_HUMAN
θ value	θ > 10 (rank : 1037)	NC score	0.051114 (rank : 900)
Query Neighborhood Hits	997	Target Neighborhood Hits	736	Shared Neighborhood Hits	71
SwissProt Accessions	Q13873, Q16569	Gene names	BMPR2, PPH1
Domain Architecture
Description	Bone morphogenetic protein receptor type-2 precursor (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II).

BMPR2_MOUSE
θ value	θ > 10 (rank : 1038)	NC score	0.051268 (rank : 895)
Query Neighborhood Hits	997	Target Neighborhood Hits	738	Shared Neighborhood Hits	75
SwissProt Accessions	O35607	Gene names	Bmpr2
Domain Architecture
Description	Bone morphogenetic protein receptor type-2 precursor (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II) (BRK-3).

BMX_HUMAN
θ value	θ > 10 (rank : 1039)	NC score	0.058275 (rank : 764)
Query Neighborhood Hits	997	Target Neighborhood Hits	942	Shared Neighborhood Hits	95
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

BMX_MOUSE
θ value	θ > 10 (rank : 1040)	NC score	0.058741 (rank : 755)
Query Neighborhood Hits	997	Target Neighborhood Hits	912	Shared Neighborhood Hits	93
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

BRAF1_HUMAN
θ value	θ > 10 (rank : 1041)	NC score	0.057318 (rank : 787)
Query Neighborhood Hits	997	Target Neighborhood Hits	883	Shared Neighborhood Hits	88
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

BRD4_HUMAN
θ value	θ > 10 (rank : 1042)	NC score	0.070281 (rank : 581)
Query Neighborhood Hits	997	Target Neighborhood Hits	851	Shared Neighborhood Hits	224
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

BRD4_MOUSE
θ value	θ > 10 (rank : 1043)	NC score	0.081933 (rank : 499)
Query Neighborhood Hits	997	Target Neighborhood Hits	845	Shared Neighborhood Hits	226
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

BTK_HUMAN
θ value	θ > 10 (rank : 1044)	NC score	0.063264 (rank : 659)
Query Neighborhood Hits	997	Target Neighborhood Hits	1026	Shared Neighborhood Hits	124
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

BTK_MOUSE
θ value	θ > 10 (rank : 1045)	NC score	0.062651 (rank : 667)
Query Neighborhood Hits	997	Target Neighborhood Hits	1017	Shared Neighborhood Hits	122
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

CBP_HUMAN
θ value	θ > 10 (rank : 1046)	NC score	0.097672 (rank : 429)
Query Neighborhood Hits	997	Target Neighborhood Hits	941	Shared Neighborhood Hits	293
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CCNK_MOUSE
θ value	θ > 10 (rank : 1047)	NC score	0.089473 (rank : 467)
Query Neighborhood Hits	997	Target Neighborhood Hits	350	Shared Neighborhood Hits	163
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CENA1_HUMAN
θ value	θ > 10 (rank : 1048)	NC score	0.055331 (rank : 813)
Query Neighborhood Hits	997	Target Neighborhood Hits	87	Shared Neighborhood Hits	29
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

CENA2_HUMAN
θ value	θ > 10 (rank : 1049)	NC score	0.051094 (rank : 901)
Query Neighborhood Hits	997	Target Neighborhood Hits	83	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

CENA2_MOUSE
θ value	θ > 10 (rank : 1050)	NC score	0.051199 (rank : 896)
Query Neighborhood Hits	997	Target Neighborhood Hits	68	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

CEND1_HUMAN
θ value	θ > 10 (rank : 1051)	NC score	0.077086 (rank : 520)
Query Neighborhood Hits	997	Target Neighborhood Hits	284	Shared Neighborhood Hits	79
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

CG1_HUMAN
θ value	θ > 10 (rank : 1052)	NC score	0.051121 (rank : 899)
Query Neighborhood Hits	997	Target Neighborhood Hits	222	Shared Neighborhood Hits	89
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

CITE4_HUMAN
θ value	θ > 10 (rank : 1053)	NC score	0.062903 (rank : 664)
Query Neighborhood Hits	997	Target Neighborhood Hits	67	Shared Neighborhood Hits	38
SwissProt Accessions	Q96RK1	Gene names	CITED4, MRG2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

CIZ1_HUMAN
θ value	θ > 10 (rank : 1054)	NC score	0.067041 (rank : 607)
Query Neighborhood Hits	997	Target Neighborhood Hits	359	Shared Neighborhood Hits	102
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

CJ078_MOUSE
θ value	θ > 10 (rank : 1055)	NC score	0.122444 (rank : 352)
Query Neighborhood Hits	997	Target Neighborhood Hits	559	Shared Neighborhood Hits	184
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CN032_HUMAN
θ value	θ > 10 (rank : 1056)	NC score	0.119609 (rank : 356)
Query Neighborhood Hits	997	Target Neighborhood Hits	267	Shared Neighborhood Hits	137
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CN032_MOUSE
θ value	θ > 10 (rank : 1057)	NC score	0.115726 (rank : 364)
Query Neighborhood Hits	997	Target Neighborhood Hits	233	Shared Neighborhood Hits	134
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CN155_HUMAN
θ value	θ > 10 (rank : 1058)	NC score	0.116482 (rank : 362)
Query Neighborhood Hits	997	Target Neighborhood Hits	385	Shared Neighborhood Hits	144
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CO002_HUMAN
θ value	θ > 10 (rank : 1059)	NC score	0.051847 (rank : 881)
Query Neighborhood Hits	997	Target Neighborhood Hits	387	Shared Neighborhood Hits	128
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

CO039_HUMAN
θ value	θ > 10 (rank : 1060)	NC score	0.067732 (rank : 600)
Query Neighborhood Hits	997	Target Neighborhood Hits	264	Shared Neighborhood Hits	133
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

CO2A1_HUMAN
θ value	θ > 10 (rank : 1061)	NC score	0.053703 (rank : 836)
Query Neighborhood Hits	997	Target Neighborhood Hits	486	Shared Neighborhood Hits	177
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO2A1_MOUSE
θ value	θ > 10 (rank : 1062)	NC score	0.053144 (rank : 848)
Query Neighborhood Hits	997	Target Neighborhood Hits	483	Shared Neighborhood Hits	170
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO9A1_MOUSE
θ value	θ > 10 (rank : 1063)	NC score	0.052057 (rank : 877)
Query Neighborhood Hits	997	Target Neighborhood Hits	477	Shared Neighborhood Hits	160
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

COAA1_HUMAN
θ value	θ > 10 (rank : 1064)	NC score	0.053331 (rank : 843)
Query Neighborhood Hits	997	Target Neighborhood Hits	316	Shared Neighborhood Hits	134
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

COGA1_HUMAN
θ value	θ > 10 (rank : 1065)	NC score	0.061613 (rank : 681)
Query Neighborhood Hits	997	Target Neighborhood Hits	345	Shared Neighborhood Hits	143
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

CS016_HUMAN
θ value	θ > 10 (rank : 1066)	NC score	0.104164 (rank : 412)
Query Neighborhood Hits	997	Target Neighborhood Hits	310	Shared Neighborhood Hits	145
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

CSF1_HUMAN
θ value	θ > 10 (rank : 1067)	NC score	0.065857 (rank : 626)
Query Neighborhood Hits	997	Target Neighborhood Hits	258	Shared Neighborhood Hits	109
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

CSK_HUMAN
θ value	θ > 10 (rank : 1068)	NC score	0.058394 (rank : 762)
Query Neighborhood Hits	997	Target Neighborhood Hits	1009	Shared Neighborhood Hits	107
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

CSK_MOUSE
θ value	θ > 10 (rank : 1069)	NC score	0.057391 (rank : 786)
Query Neighborhood Hits	997	Target Neighborhood Hits	1009	Shared Neighborhood Hits	107
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

CT151_HUMAN
θ value	θ > 10 (rank : 1070)	NC score	0.054483 (rank : 827)
Query Neighborhood Hits	997	Target Neighborhood Hits	382	Shared Neighborhood Hits	93
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

CU081_HUMAN
θ value	θ > 10 (rank : 1071)	NC score	0.092984 (rank : 450)
Query Neighborhood Hits	997	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

DDR1_HUMAN
θ value	θ > 10 (rank : 1072)	NC score	0.061521 (rank : 683)
Query Neighborhood Hits	997	Target Neighborhood Hits	819	Shared Neighborhood Hits	79
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

DDR1_MOUSE
θ value	θ > 10 (rank : 1073)	NC score	0.061196 (rank : 690)
Query Neighborhood Hits	997	Target Neighborhood Hits	818	Shared Neighborhood Hits	79
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

DDR2_HUMAN
θ value	θ > 10 (rank : 1074)	NC score	0.059682 (rank : 731)
Query Neighborhood Hits	997	Target Neighborhood Hits	818	Shared Neighborhood Hits	76
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DDR2_MOUSE
θ value	θ > 10 (rank : 1075)	NC score	0.059332 (rank : 738)
Query Neighborhood Hits	997	Target Neighborhood Hits	813	Shared Neighborhood Hits	78
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DGKK_HUMAN
θ value	θ > 10 (rank : 1076)	NC score	0.091953 (rank : 455)
Query Neighborhood Hits	997	Target Neighborhood Hits	378	Shared Neighborhood Hits	149
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

EFS_HUMAN
θ value	θ > 10 (rank : 1077)	NC score	0.066064 (rank : 620)
Query Neighborhood Hits	997	Target Neighborhood Hits	348	Shared Neighborhood Hits	136
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

EGFR_HUMAN
θ value	θ > 10 (rank : 1078)	NC score	0.061030 (rank : 692)
Query Neighborhood Hits	997	Target Neighborhood Hits	939	Shared Neighborhood Hits	81
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

EGFR_MOUSE
θ value	θ > 10 (rank : 1079)	NC score	0.060893 (rank : 698)
Query Neighborhood Hits	997	Target Neighborhood Hits	927	Shared Neighborhood Hits	81
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

EMID2_HUMAN
θ value	θ > 10 (rank : 1080)	NC score	0.052084 (rank : 876)
Query Neighborhood Hits	997	Target Neighborhood Hits	226	Shared Neighborhood Hits	106
SwissProt Accessions	Q96A83	Gene names	EMID2, COL26A1, EMU2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

ENAH_HUMAN
θ value	θ > 10 (rank : 1081)	NC score	0.054985 (rank : 819)
Query Neighborhood Hits	997	Target Neighborhood Hits	784	Shared Neighborhood Hits	169
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

ENAH_MOUSE
θ value	θ > 10 (rank : 1082)	NC score	0.112837 (rank : 368)
Query Neighborhood Hits	997	Target Neighborhood Hits	919	Shared Neighborhood Hits	258
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

ENL_HUMAN
θ value	θ > 10 (rank : 1083)	NC score	0.056056 (rank : 803)
Query Neighborhood Hits	997	Target Neighborhood Hits	305	Shared Neighborhood Hits	93
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

EP300_HUMAN
θ value	θ > 10 (rank : 1084)	NC score	0.095668 (rank : 441)
Query Neighborhood Hits	997	Target Neighborhood Hits	821	Shared Neighborhood Hits	296
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

ERBB2_HUMAN
θ value	θ > 10 (rank : 1085)	NC score	0.064181 (rank : 643)
Query Neighborhood Hits	997	Target Neighborhood Hits	1073	Shared Neighborhood Hits	139
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

ERBB2_MOUSE
θ value	θ > 10 (rank : 1086)	NC score	0.062634 (rank : 668)
Query Neighborhood Hits	997	Target Neighborhood Hits	918	Shared Neighborhood Hits	91
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

ERBB3_HUMAN
θ value	θ > 10 (rank : 1087)	NC score	0.056985 (rank : 793)
Query Neighborhood Hits	997	Target Neighborhood Hits	918	Shared Neighborhood Hits	83
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

ERBB3_MOUSE
θ value	θ > 10 (rank : 1088)	NC score	0.056370 (rank : 799)
Query Neighborhood Hits	997	Target Neighborhood Hits	898	Shared Neighborhood Hits	84
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

ERBB4_HUMAN
θ value	θ > 10 (rank : 1089)	NC score	0.063958 (rank : 648)
Query Neighborhood Hits	997	Target Neighborhood Hits	910	Shared Neighborhood Hits	87
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

FAK1_HUMAN
θ value	θ > 10 (rank : 1090)	NC score	0.062564 (rank : 670)
Query Neighborhood Hits	997	Target Neighborhood Hits	850	Shared Neighborhood Hits	87
SwissProt Accessions	Q05397, Q14291, Q9UD85	Gene names	PTK2, FAK, FAK1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2).

FAK1_MOUSE
θ value	θ > 10 (rank : 1091)	NC score	0.062235 (rank : 674)
Query Neighborhood Hits	997	Target Neighborhood Hits	850	Shared Neighborhood Hits	82
SwissProt Accessions	P34152, O08578	Gene names	Ptk2, Fadk, Fak, Fak1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK).

FAK2_HUMAN
θ value	θ > 10 (rank : 1092)	NC score	0.063129 (rank : 662)
Query Neighborhood Hits	997	Target Neighborhood Hits	847	Shared Neighborhood Hits	80
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

FAK2_MOUSE
θ value	θ > 10 (rank : 1093)	NC score	0.062663 (rank : 666)
Query Neighborhood Hits	997	Target Neighborhood Hits	851	Shared Neighborhood Hits	80
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

FER_HUMAN
θ value	θ > 10 (rank : 1094)	NC score	0.062556 (rank : 671)
Query Neighborhood Hits	997	Target Neighborhood Hits	1278	Shared Neighborhood Hits	112
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

FES_HUMAN
θ value	θ > 10 (rank : 1095)	NC score	0.058953 (rank : 750)
Query Neighborhood Hits	997	Target Neighborhood Hits	978	Shared Neighborhood Hits	87
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

FES_MOUSE
θ value	θ > 10 (rank : 1096)	NC score	0.059841 (rank : 726)
Query Neighborhood Hits	997	Target Neighborhood Hits	980	Shared Neighborhood Hits	99
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

FGFR3_HUMAN
θ value	θ > 10 (rank : 1097)	NC score	0.050081 (rank : 933)
Query Neighborhood Hits	997	Target Neighborhood Hits	1042	Shared Neighborhood Hits	80
SwissProt Accessions	P22607, Q14308, Q16294, Q16608	Gene names	FGFR3, JTK4
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (CD333 antigen).

FGFR4_HUMAN
θ value	θ > 10 (rank : 1098)	NC score	0.050119 (rank : 931)
Query Neighborhood Hits	997	Target Neighborhood Hits	1037	Shared Neighborhood Hits	83
SwissProt Accessions	P22455, O43785, Q14309	Gene names	FGFR4, JTK2, TKF
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (CD334 antigen).

FGFR4_MOUSE
θ value	θ > 10 (rank : 1099)	NC score	0.050826 (rank : 915)
Query Neighborhood Hits	997	Target Neighborhood Hits	1026	Shared Neighborhood Hits	83
SwissProt Accessions	Q03142, Q5J7D9, Q8C3V5, Q8CIB8	Gene names	Fgfr4, Fgfr-4, Mpk-11
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) (CD334 antigen).

FGR_HUMAN
θ value	θ > 10 (rank : 1100)	NC score	0.063534 (rank : 652)
Query Neighborhood Hits	997	Target Neighborhood Hits	1067	Shared Neighborhood Hits	129
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FGR_MOUSE
θ value	θ > 10 (rank : 1101)	NC score	0.063990 (rank : 647)
Query Neighborhood Hits	997	Target Neighborhood Hits	1069	Shared Neighborhood Hits	125
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FMN1B_MOUSE
θ value	θ > 10 (rank : 1102)	NC score	0.068592 (rank : 594)
Query Neighborhood Hits	997	Target Neighborhood Hits	447	Shared Neighborhood Hits	167
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

FRK_HUMAN
θ value	θ > 10 (rank : 1103)	NC score	0.062067 (rank : 676)
Query Neighborhood Hits	997	Target Neighborhood Hits	1058	Shared Neighborhood Hits	120
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

FYN_HUMAN
θ value	θ > 10 (rank : 1104)	NC score	0.063357 (rank : 657)
Query Neighborhood Hits	997	Target Neighborhood Hits	1078	Shared Neighborhood Hits	126
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

FYN_MOUSE
θ value	θ > 10 (rank : 1105)	NC score	0.063893 (rank : 649)
Query Neighborhood Hits	997	Target Neighborhood Hits	1073	Shared Neighborhood Hits	124
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

GGN_HUMAN
θ value	θ > 10 (rank : 1106)	NC score	0.110939 (rank : 379)
Query Neighborhood Hits	997	Target Neighborhood Hits	269	Shared Neighborhood Hits	142
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GRIN1_HUMAN
θ value	θ > 10 (rank : 1107)	NC score	0.093543 (rank : 448)
Query Neighborhood Hits	997	Target Neighborhood Hits	681	Shared Neighborhood Hits	222
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

GTSE1_HUMAN
θ value	θ > 10 (rank : 1108)	NC score	0.050087 (rank : 932)
Query Neighborhood Hits	997	Target Neighborhood Hits	193	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

GUC2C_HUMAN
θ value	θ > 10 (rank : 1109)	NC score	0.057503 (rank : 782)
Query Neighborhood Hits	997	Target Neighborhood Hits	624	Shared Neighborhood Hits	64
SwissProt Accessions	P25092	Gene names	GUCY2C, GUC2C, STAR
Domain Architecture
Description	Heat-stable enterotoxin receptor precursor (GC-C) (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR).

GUC2E_MOUSE
θ value	θ > 10 (rank : 1110)	NC score	0.052783 (rank : 859)
Query Neighborhood Hits	997	Target Neighborhood Hits	692	Shared Neighborhood Hits	66
SwissProt Accessions	P52785	Gene names	Gucy2e, Guc2e
Domain Architecture
Description	Guanylyl cyclase GC-E precursor (EC 4.6.1.2) (Guanylate cyclase 2E).

GUC2F_HUMAN
θ value	θ > 10 (rank : 1111)	NC score	0.056028 (rank : 805)
Query Neighborhood Hits	997	Target Neighborhood Hits	740	Shared Neighborhood Hits	69
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

GUC2G_MOUSE
θ value	θ > 10 (rank : 1112)	NC score	0.059788 (rank : 728)
Query Neighborhood Hits	997	Target Neighborhood Hits	644	Shared Neighborhood Hits	67
SwissProt Accessions	Q6TL19, Q8BWU7	Gene names	Gucy2g
Domain Architecture	No domain graphic available
Description	Guanylate cyclase 2G precursor (EC 4.6.1.2) (Guanylyl cyclase receptor G) (mGC-G).

HCK_HUMAN
θ value	θ > 10 (rank : 1113)	NC score	0.061388 (rank : 686)
Query Neighborhood Hits	997	Target Neighborhood Hits	1035	Shared Neighborhood Hits	123
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

HCK_MOUSE
θ value	θ > 10 (rank : 1114)	NC score	0.061566 (rank : 682)
Query Neighborhood Hits	997	Target Neighborhood Hits	1029	Shared Neighborhood Hits	121
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

IF35_MOUSE
θ value	θ > 10 (rank : 1115)	NC score	0.058475 (rank : 761)
Query Neighborhood Hits	997	Target Neighborhood Hits	210	Shared Neighborhood Hits	116
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

IF4G1_HUMAN
θ value	θ > 10 (rank : 1116)	NC score	0.050033 (rank : 935)
Query Neighborhood Hits	997	Target Neighborhood Hits	347	Shared Neighborhood Hits	116
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

IF4G1_MOUSE
θ value	θ > 10 (rank : 1117)	NC score	0.055912 (rank : 806)
Query Neighborhood Hits	997	Target Neighborhood Hits	534	Shared Neighborhood Hits	185
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

IGF1R_HUMAN
θ value	θ > 10 (rank : 1118)	NC score	0.057894 (rank : 772)
Query Neighborhood Hits	997	Target Neighborhood Hits	977	Shared Neighborhood Hits	86
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IGF1R_MOUSE
θ value	θ > 10 (rank : 1119)	NC score	0.058259 (rank : 765)
Query Neighborhood Hits	997	Target Neighborhood Hits	973	Shared Neighborhood Hits	89
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

INSRR_HUMAN
θ value	θ > 10 (rank : 1120)	NC score	0.060232 (rank : 720)
Query Neighborhood Hits	997	Target Neighborhood Hits	950	Shared Neighborhood Hits	93
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

INSRR_MOUSE
θ value	θ > 10 (rank : 1121)	NC score	0.060228 (rank : 721)
Query Neighborhood Hits	997	Target Neighborhood Hits	961	Shared Neighborhood Hits	92
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

INSR_HUMAN
θ value	θ > 10 (rank : 1122)	NC score	0.060762 (rank : 703)
Query Neighborhood Hits	997	Target Neighborhood Hits	963	Shared Neighborhood Hits	84
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

INSR_MOUSE
θ value	θ > 10 (rank : 1123)	NC score	0.059742 (rank : 730)
Query Neighborhood Hits	997	Target Neighborhood Hits	968	Shared Neighborhood Hits	83
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

IRAK1_HUMAN
θ value	θ > 10 (rank : 1124)	NC score	0.062599 (rank : 669)
Query Neighborhood Hits	997	Target Neighborhood Hits	820	Shared Neighborhood Hits	108
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

IRAK1_MOUSE
θ value	θ > 10 (rank : 1125)	NC score	0.056652 (rank : 797)
Query Neighborhood Hits	997	Target Neighborhood Hits	784	Shared Neighborhood Hits	86
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

IRAK3_HUMAN
θ value	θ > 10 (rank : 1126)	NC score	0.067451 (rank : 602)
Query Neighborhood Hits	997	Target Neighborhood Hits	644	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y616	Gene names	IRAK3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

IRAK3_MOUSE
θ value	θ > 10 (rank : 1127)	NC score	0.065929 (rank : 623)
Query Neighborhood Hits	997	Target Neighborhood Hits	628	Shared Neighborhood Hits	70
SwissProt Accessions	Q8K4B2, Q8C7U8, Q8CE40, Q8K1S8	Gene names	Irak3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

IRS2_HUMAN
θ value	θ > 10 (rank : 1128)	NC score	0.053000 (rank : 852)
Query Neighborhood Hits	997	Target Neighborhood Hits	262	Shared Neighborhood Hits	119
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

ITK_HUMAN
θ value	θ > 10 (rank : 1129)	NC score	0.061178 (rank : 691)
Query Neighborhood Hits	997	Target Neighborhood Hits	1016	Shared Neighborhood Hits	109
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

ITK_MOUSE
θ value	θ > 10 (rank : 1130)	NC score	0.060604 (rank : 708)
Query Neighborhood Hits	997	Target Neighborhood Hits	985	Shared Neighborhood Hits	105
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

IWS1_HUMAN
θ value	θ > 10 (rank : 1131)	NC score	0.065122 (rank : 635)
Query Neighborhood Hits	997	Target Neighborhood Hits	1241	Shared Neighborhood Hits	191
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

JAK1_HUMAN
θ value	θ > 10 (rank : 1132)	NC score	0.053419 (rank : 840)
Query Neighborhood Hits	997	Target Neighborhood Hits	858	Shared Neighborhood Hits	77
SwissProt Accessions	P23458	Gene names	JAK1, JAK1A
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

JAK1_MOUSE
θ value	θ > 10 (rank : 1133)	NC score	0.053155 (rank : 847)
Query Neighborhood Hits	997	Target Neighborhood Hits	854	Shared Neighborhood Hits	77
SwissProt Accessions	P52332, Q62126	Gene names	Jak1
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

JAK2_HUMAN
θ value	θ > 10 (rank : 1134)	NC score	0.052092 (rank : 875)
Query Neighborhood Hits	997	Target Neighborhood Hits	847	Shared Neighborhood Hits	77
SwissProt Accessions	O60674, O14636, O75297	Gene names	JAK2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

JAK2_MOUSE
θ value	θ > 10 (rank : 1135)	NC score	0.051123 (rank : 898)
Query Neighborhood Hits	997	Target Neighborhood Hits	839	Shared Neighborhood Hits	77
SwissProt Accessions	Q62120, Q62124	Gene names	Jak2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

JAK3_HUMAN
θ value	θ > 10 (rank : 1136)	NC score	0.051158 (rank : 897)
Query Neighborhood Hits	997	Target Neighborhood Hits	827	Shared Neighborhood Hits	77
SwissProt Accessions	P52333, Q13259, Q13260, Q13611, Q9Y6S2	Gene names	JAK3
Domain Architecture
Description	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK).

KIT_HUMAN
θ value	θ > 10 (rank : 1137)	NC score	0.052307 (rank : 866)
Query Neighborhood Hits	997	Target Neighborhood Hits	953	Shared Neighborhood Hits	76
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

KIT_MOUSE
θ value	θ > 10 (rank : 1138)	NC score	0.051975 (rank : 879)
Query Neighborhood Hits	997	Target Neighborhood Hits	949	Shared Neighborhood Hits	79
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

KSR1_HUMAN
θ value	θ > 10 (rank : 1139)	NC score	0.052946 (rank : 856)
Query Neighborhood Hits	997	Target Neighborhood Hits	867	Shared Neighborhood Hits	91
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

KSR1_MOUSE
θ value	θ > 10 (rank : 1140)	NC score	0.050011 (rank : 936)
Query Neighborhood Hits	997	Target Neighborhood Hits	870	Shared Neighborhood Hits	84
SwissProt Accessions	Q61097, Q61648, Q78DX8	Gene names	Ksr1, Ksr
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein).

KSR2_HUMAN
θ value	θ > 10 (rank : 1141)	NC score	0.052392 (rank : 865)
Query Neighborhood Hits	997	Target Neighborhood Hits	920	Shared Neighborhood Hits	119
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

KSYK_HUMAN
θ value	θ > 10 (rank : 1142)	NC score	0.059462 (rank : 735)
Query Neighborhood Hits	997	Target Neighborhood Hits	901	Shared Neighborhood Hits	85
SwissProt Accessions	P43405	Gene names	SYK
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

KSYK_MOUSE
θ value	θ > 10 (rank : 1143)	NC score	0.060332 (rank : 717)
Query Neighborhood Hits	997	Target Neighborhood Hits	944	Shared Neighborhood Hits	101
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

LAD1_MOUSE
θ value	θ > 10 (rank : 1144)	NC score	0.082972 (rank : 497)
Query Neighborhood Hits	997	Target Neighborhood Hits	391	Shared Neighborhood Hits	110
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

LCE1B_HUMAN
θ value	θ > 10 (rank : 1145)	NC score	0.050003 (rank : 937)
Query Neighborhood Hits	997	Target Neighborhood Hits	58	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCK_HUMAN
θ value	θ > 10 (rank : 1146)	NC score	0.060444 (rank : 714)
Query Neighborhood Hits	997	Target Neighborhood Hits	987	Shared Neighborhood Hits	106
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

LCK_MOUSE
θ value	θ > 10 (rank : 1147)	NC score	0.061004 (rank : 694)
Query Neighborhood Hits	997	Target Neighborhood Hits	981	Shared Neighborhood Hits	105
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

LTBP2_MOUSE
θ value	θ > 10 (rank : 1148)	NC score	0.051043 (rank : 906)
Query Neighborhood Hits	997	Target Neighborhood Hits	617	Shared Neighborhood Hits	88
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTK_HUMAN
θ value	θ > 10 (rank : 1149)	NC score	0.061230 (rank : 689)
Query Neighborhood Hits	997	Target Neighborhood Hits	774	Shared Neighborhood Hits	79
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

LTK_MOUSE
θ value	θ > 10 (rank : 1150)	NC score	0.060893 (rank : 699)
Query Neighborhood Hits	997	Target Neighborhood Hits	770	Shared Neighborhood Hits	80
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

LYN_HUMAN
θ value	θ > 10 (rank : 1151)	NC score	0.059896 (rank : 725)
Query Neighborhood Hits	997	Target Neighborhood Hits	1022	Shared Neighborhood Hits	120
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

LYN_MOUSE
θ value	θ > 10 (rank : 1152)	NC score	0.060046 (rank : 723)
Query Neighborhood Hits	997	Target Neighborhood Hits	1023	Shared Neighborhood Hits	123
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

M3K10_HUMAN
θ value	θ > 10 (rank : 1153)	NC score	0.066484 (rank : 611)
Query Neighborhood Hits	997	Target Neighborhood Hits	1071	Shared Neighborhood Hits	144
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

M3K12_HUMAN
θ value	θ > 10 (rank : 1154)	NC score	0.057856 (rank : 775)
Query Neighborhood Hits	997	Target Neighborhood Hits	940	Shared Neighborhood Hits	121
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

M3K12_MOUSE
θ value	θ > 10 (rank : 1155)	NC score	0.057264 (rank : 789)
Query Neighborhood Hits	997	Target Neighborhood Hits	957	Shared Neighborhood Hits	113
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

M3K13_HUMAN
θ value	θ > 10 (rank : 1156)	NC score	0.054475 (rank : 828)
Query Neighborhood Hits	997	Target Neighborhood Hits	911	Shared Neighborhood Hits	88
SwissProt Accessions	O43283	Gene names	MAP3K13, LZK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase).

M3K7_HUMAN
θ value	θ > 10 (rank : 1157)	NC score	0.059200 (rank : 743)
Query Neighborhood Hits	997	Target Neighborhood Hits	892	Shared Neighborhood Hits	79
SwissProt Accessions	O43318, O43317, O43319, Q5TDN2, Q5TDN3	Gene names	MAP3K7, TAK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

M3K7_MOUSE
θ value	θ > 10 (rank : 1158)	NC score	0.059234 (rank : 741)
Query Neighborhood Hits	997	Target Neighborhood Hits	892	Shared Neighborhood Hits	79
SwissProt Accessions	Q62073	Gene names	Map3k7, Tak1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

M3K9_HUMAN
θ value	θ > 10 (rank : 1159)	NC score	0.064923 (rank : 636)
Query Neighborhood Hits	997	Target Neighborhood Hits	1123	Shared Neighborhood Hits	166
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

M3KL4_HUMAN
θ value	θ > 10 (rank : 1160)	NC score	0.064665 (rank : 641)
Query Neighborhood Hits	997	Target Neighborhood Hits	1087	Shared Neighborhood Hits	139
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

MADCA_HUMAN
θ value	θ > 10 (rank : 1161)	NC score	0.078885 (rank : 510)
Query Neighborhood Hits	997	Target Neighborhood Hits	221	Shared Neighborhood Hits	104
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

MAP1B_HUMAN
θ value	θ > 10 (rank : 1162)	NC score	0.052860 (rank : 858)
Query Neighborhood Hits	997	Target Neighborhood Hits	903	Shared Neighborhood Hits	135
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MAP1B_MOUSE
θ value	θ > 10 (rank : 1163)	NC score	0.050191 (rank : 929)
Query Neighborhood Hits	997	Target Neighborhood Hits	977	Shared Neighborhood Hits	161
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MAP4_MOUSE
θ value	θ > 10 (rank : 1164)	NC score	0.072842 (rank : 554)
Query Neighborhood Hits	997	Target Neighborhood Hits	409	Shared Neighborhood Hits	116
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MARCS_MOUSE
θ value	θ > 10 (rank : 1165)	NC score	0.088940 (rank : 468)
Query Neighborhood Hits	997	Target Neighborhood Hits	227	Shared Neighborhood Hits	93
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MATK_HUMAN
θ value	θ > 10 (rank : 1166)	NC score	0.059520 (rank : 734)
Query Neighborhood Hits	997	Target Neighborhood Hits	954	Shared Neighborhood Hits	101
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

MATK_MOUSE
θ value	θ > 10 (rank : 1167)	NC score	0.059235 (rank : 740)
Query Neighborhood Hits	997	Target Neighborhood Hits	952	Shared Neighborhood Hits	102
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

MAVS_HUMAN
θ value	θ > 10 (rank : 1168)	NC score	0.058756 (rank : 754)
Query Neighborhood Hits	997	Target Neighborhood Hits	271	Shared Neighborhood Hits	97
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

MBD6_HUMAN
θ value	θ > 10 (rank : 1169)	NC score	0.138957 (rank : 328)
Query Neighborhood Hits	997	Target Neighborhood Hits	349	Shared Neighborhood Hits	171
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MEGF9_HUMAN
θ value	θ > 10 (rank : 1170)	NC score	0.056619 (rank : 798)
Query Neighborhood Hits	997	Target Neighborhood Hits	557	Shared Neighborhood Hits	136
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MERTK_HUMAN
θ value	θ > 10 (rank : 1171)	NC score	0.059074 (rank : 746)
Query Neighborhood Hits	997	Target Neighborhood Hits	988	Shared Neighborhood Hits	86
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

MERTK_MOUSE
θ value	θ > 10 (rank : 1172)	NC score	0.058862 (rank : 752)
Query Neighborhood Hits	997	Target Neighborhood Hits	974	Shared Neighborhood Hits	82
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

MET_HUMAN
θ value	θ > 10 (rank : 1173)	NC score	0.060523 (rank : 712)
Query Neighborhood Hits	997	Target Neighborhood Hits	831	Shared Neighborhood Hits	77
SwissProt Accessions	P08581, O60366, Q12875, Q9UDX7, Q9UPL8	Gene names	MET
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

MET_MOUSE
θ value	θ > 10 (rank : 1174)	NC score	0.060310 (rank : 718)
Query Neighborhood Hits	997	Target Neighborhood Hits	844	Shared Neighborhood Hits	80
SwissProt Accessions	P16056, Q62125	Gene names	Met
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

MILK1_HUMAN
θ value	θ > 10 (rank : 1175)	NC score	0.067200 (rank : 606)
Query Neighborhood Hits	997	Target Neighborhood Hits	427	Shared Neighborhood Hits	157
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MINT_HUMAN
θ value	θ > 10 (rank : 1176)	NC score	0.071324 (rank : 572)
Query Neighborhood Hits	997	Target Neighborhood Hits	1291	Shared Neighborhood Hits	257
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MLKL_HUMAN
θ value	θ > 10 (rank : 1177)	NC score	0.069009 (rank : 587)
Query Neighborhood Hits	997	Target Neighborhood Hits	600	Shared Neighborhood Hits	63
SwissProt Accessions	Q8NB16, Q8N6V0	Gene names	MLKL
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

MLKL_MOUSE
θ value	θ > 10 (rank : 1178)	NC score	0.062174 (rank : 675)
Query Neighborhood Hits	997	Target Neighborhood Hits	707	Shared Neighborhood Hits	71
SwissProt Accessions	Q9D2Y4, Q8CIJ5	Gene names	Mlkl
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

MLTK_HUMAN
θ value	θ > 10 (rank : 1179)	NC score	0.057889 (rank : 773)
Query Neighborhood Hits	997	Target Neighborhood Hits	911	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NYL2, Q53SX1, Q580W8, Q59GY5, Q86YW8, Q9HCC4, Q9HCC5, Q9HDD2, Q9NYE9	Gene names	MLTK, ZAK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Cervical cancer suppressor gene 4 protein).

MLTK_MOUSE
θ value	θ > 10 (rank : 1180)	NC score	0.057619 (rank : 779)
Query Neighborhood Hits	997	Target Neighborhood Hits	874	Shared Neighborhood Hits	85
SwissProt Accessions	Q9ESL4, Q3V1X8, Q8BR73, Q9ESL3	Gene names	Mltk
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK).

MOS_HUMAN
θ value	θ > 10 (rank : 1181)	NC score	0.053589 (rank : 837)
Query Neighborhood Hits	997	Target Neighborhood Hits	829	Shared Neighborhood Hits	77
SwissProt Accessions	P00540	Gene names	MOS
Domain Architecture
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

MTSS1_MOUSE
θ value	θ > 10 (rank : 1182)	NC score	0.067415 (rank : 603)
Query Neighborhood Hits	997	Target Neighborhood Hits	592	Shared Neighborhood Hits	209
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

MUC13_MOUSE
θ value	θ > 10 (rank : 1183)	NC score	0.083333 (rank : 496)
Query Neighborhood Hits	997	Target Neighborhood Hits	447	Shared Neighborhood Hits	111
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

MUC1_MOUSE
θ value	θ > 10 (rank : 1184)	NC score	0.089831 (rank : 464)
Query Neighborhood Hits	997	Target Neighborhood Hits	388	Shared Neighborhood Hits	93
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

MUC2_HUMAN
θ value	θ > 10 (rank : 1185)	NC score	0.100228 (rank : 421)
Query Neighborhood Hits	997	Target Neighborhood Hits	906	Shared Neighborhood Hits	237
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MUC5B_HUMAN
θ value	θ > 10 (rank : 1186)	NC score	0.070358 (rank : 580)
Query Neighborhood Hits	997	Target Neighborhood Hits	1020	Shared Neighborhood Hits	200
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MUC7_HUMAN
θ value	θ > 10 (rank : 1187)	NC score	0.154117 (rank : 316)
Query Neighborhood Hits	997	Target Neighborhood Hits	538	Shared Neighborhood Hits	208
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

MUSK_HUMAN
θ value	θ > 10 (rank : 1188)	NC score	0.053404 (rank : 841)
Query Neighborhood Hits	997	Target Neighborhood Hits	1074	Shared Neighborhood Hits	77
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

MUSK_MOUSE
θ value	θ > 10 (rank : 1189)	NC score	0.052718 (rank : 860)
Query Neighborhood Hits	997	Target Neighborhood Hits	1057	Shared Neighborhood Hits	76
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

NELFA_HUMAN
θ value	θ > 10 (rank : 1190)	NC score	0.058953 (rank : 749)
Query Neighborhood Hits	997	Target Neighborhood Hits	161	Shared Neighborhood Hits	89
SwissProt Accessions	Q9H3P2, O95392	Gene names	WHSC2, NELFA
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein).

NELFA_MOUSE
θ value	θ > 10 (rank : 1191)	NC score	0.061347 (rank : 687)
Query Neighborhood Hits	997	Target Neighborhood Hits	195	Shared Neighborhood Hits	102
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

NOLC1_HUMAN
θ value	θ > 10 (rank : 1192)	NC score	0.088017 (rank : 472)
Query Neighborhood Hits	997	Target Neighborhood Hits	452	Shared Neighborhood Hits	110
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

NSD1_MOUSE
θ value	θ > 10 (rank : 1193)	NC score	0.050871 (rank : 913)
Query Neighborhood Hits	997	Target Neighborhood Hits	472	Shared Neighborhood Hits	110
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

NTRK1_HUMAN
θ value	θ > 10 (rank : 1194)	NC score	0.058357 (rank : 763)
Query Neighborhood Hits	997	Target Neighborhood Hits	1023	Shared Neighborhood Hits	76
SwissProt Accessions	P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7	Gene names	NTRK1, TRK
Domain Architecture
Description	High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A).

NTRK2_HUMAN
θ value	θ > 10 (rank : 1195)	NC score	0.055131 (rank : 816)
Query Neighborhood Hits	997	Target Neighborhood Hits	1081	Shared Neighborhood Hits	79
SwissProt Accessions	Q16620, Q16675, Q8WXJ6	Gene names	NTRK2, TRKB
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

NTRK2_MOUSE
θ value	θ > 10 (rank : 1196)	NC score	0.055010 (rank : 818)
Query Neighborhood Hits	997	Target Neighborhood Hits	1088	Shared Neighborhood Hits	79
SwissProt Accessions	P15209, Q3TUF9, Q80WU0, Q91XJ9	Gene names	Ntrk2, Trkb
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B).

NTRK3_HUMAN
θ value	θ > 10 (rank : 1197)	NC score	0.055522 (rank : 811)
Query Neighborhood Hits	997	Target Neighborhood Hits	1115	Shared Neighborhood Hits	82
SwissProt Accessions	Q16288, Q12827, Q16289	Gene names	NTRK3, TRKC
Domain Architecture
Description	NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C).

NU214_HUMAN
θ value	θ > 10 (rank : 1198)	NC score	0.090552 (rank : 458)
Query Neighborhood Hits	997	Target Neighborhood Hits	657	Shared Neighborhood Hits	165
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

NUMBL_HUMAN
θ value	θ > 10 (rank : 1199)	NC score	0.053719 (rank : 835)
Query Neighborhood Hits	997	Target Neighborhood Hits	394	Shared Neighborhood Hits	134
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

PCQAP_HUMAN
θ value	θ > 10 (rank : 1200)	NC score	0.088491 (rank : 470)
Query Neighborhood Hits	997	Target Neighborhood Hits	549	Shared Neighborhood Hits	158
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PCQAP_MOUSE
θ value	θ > 10 (rank : 1201)	NC score	0.065891 (rank : 624)
Query Neighborhood Hits	997	Target Neighborhood Hits	506	Shared Neighborhood Hits	147
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

PDC6I_HUMAN
θ value	θ > 10 (rank : 1202)	NC score	0.057954 (rank : 770)
Query Neighborhood Hits	997	Target Neighborhood Hits	278	Shared Neighborhood Hits	128
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

PDCD7_HUMAN
θ value	θ > 10 (rank : 1203)	NC score	0.053354 (rank : 842)
Query Neighborhood Hits	997	Target Neighborhood Hits	255	Shared Neighborhood Hits	70
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

PELP1_HUMAN
θ value	θ > 10 (rank : 1204)	NC score	0.083560 (rank : 492)
Query Neighborhood Hits	997	Target Neighborhood Hits	596	Shared Neighborhood Hits	163
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PGFRB_HUMAN
θ value	θ > 10 (rank : 1205)	NC score	0.050216 (rank : 927)
Query Neighborhood Hits	997	Target Neighborhood Hits	962	Shared Neighborhood Hits	77
SwissProt Accessions	P09619, Q8N5L4	Gene names	PDGFRB
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

PGFRB_MOUSE
θ value	θ > 10 (rank : 1206)	NC score	0.050034 (rank : 934)
Query Neighborhood Hits	997	Target Neighborhood Hits	960	Shared Neighborhood Hits	77
SwissProt Accessions	P05622	Gene names	Pdgfrb, Pdgfr
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

PI5PA_MOUSE
θ value	θ > 10 (rank : 1207)	NC score	0.078288 (rank : 515)
Query Neighborhood Hits	997	Target Neighborhood Hits	331	Shared Neighborhood Hits	155
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PO121_HUMAN
θ value	θ > 10 (rank : 1208)	NC score	0.079283 (rank : 509)
Query Neighborhood Hits	997	Target Neighborhood Hits	344	Shared Neighborhood Hits	127
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PO121_MOUSE
θ value	θ > 10 (rank : 1209)	NC score	0.073086 (rank : 553)
Query Neighborhood Hits	997	Target Neighborhood Hits	345	Shared Neighborhood Hits	120
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

PRCC_HUMAN
θ value	θ > 10 (rank : 1210)	NC score	0.053067 (rank : 851)
Query Neighborhood Hits	997	Target Neighborhood Hits	109	Shared Neighborhood Hits	57
SwissProt Accessions	Q92733, O00665, O00724	Gene names	PRCC, TPRC
Domain Architecture	No domain graphic available
Description	Proline-rich protein PRCC (Papillary renal cell carcinoma translocation-associated gene protein).

PRP5_HUMAN
θ value	θ > 10 (rank : 1211)	NC score	0.102234 (rank : 417)
Query Neighborhood Hits	997	Target Neighborhood Hits	108	Shared Neighborhood Hits	63
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

PRPC_HUMAN
θ value	θ > 10 (rank : 1212)	NC score	0.087517 (rank : 475)
Query Neighborhood Hits	997	Target Neighborhood Hits	165	Shared Neighborhood Hits	67
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

PRPE_HUMAN
θ value	θ > 10 (rank : 1213)	NC score	0.090347 (rank : 460)
Query Neighborhood Hits	997	Target Neighborhood Hits	44	Shared Neighborhood Hits	24
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

PRR12_HUMAN
θ value	θ > 10 (rank : 1214)	NC score	0.162146 (rank : 310)
Query Neighborhood Hits	997	Target Neighborhood Hits	460	Shared Neighborhood Hits	211
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PRR13_HUMAN
θ value	θ > 10 (rank : 1215)	NC score	0.106696 (rank : 403)
Query Neighborhood Hits	997	Target Neighborhood Hits	105	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PRR13_MOUSE
θ value	θ > 10 (rank : 1216)	NC score	0.096454 (rank : 437)
Query Neighborhood Hits	997	Target Neighborhood Hits	54	Shared Neighborhood Hits	37
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PS1C2_HUMAN
θ value	θ > 10 (rank : 1217)	NC score	0.057307 (rank : 788)
Query Neighborhood Hits	997	Target Neighborhood Hits	66	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UIG4	Gene names	PSORS1C2, C6orf17, SPR1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein precursor (SPR1 protein).

PTK6_HUMAN
θ value	θ > 10 (rank : 1218)	NC score	0.059551 (rank : 733)
Query Neighborhood Hits	997	Target Neighborhood Hits	1020	Shared Neighborhood Hits	116
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

PTK6_MOUSE
θ value	θ > 10 (rank : 1219)	NC score	0.060053 (rank : 722)
Query Neighborhood Hits	997	Target Neighborhood Hits	1026	Shared Neighborhood Hits	116
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

PTN23_MOUSE
θ value	θ > 10 (rank : 1220)	NC score	0.051492 (rank : 890)
Query Neighborhood Hits	997	Target Neighborhood Hits	726	Shared Neighborhood Hits	232
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PYGO2_HUMAN
θ value	θ > 10 (rank : 1221)	NC score	0.051510 (rank : 889)
Query Neighborhood Hits	997	Target Neighborhood Hits	189	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

RAF1_HUMAN
θ value	θ > 10 (rank : 1222)	NC score	0.057529 (rank : 781)
Query Neighborhood Hits	997	Target Neighborhood Hits	886	Shared Neighborhood Hits	85
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RAF1_MOUSE
θ value	θ > 10 (rank : 1223)	NC score	0.057497 (rank : 783)
Query Neighborhood Hits	997	Target Neighborhood Hits	886	Shared Neighborhood Hits	85
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RBM12_MOUSE
θ value	θ > 10 (rank : 1224)	NC score	0.052549 (rank : 862)
Query Neighborhood Hits	997	Target Neighborhood Hits	313	Shared Neighborhood Hits	122
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

RELB_HUMAN
θ value	θ > 10 (rank : 1225)	NC score	0.050999 (rank : 909)
Query Neighborhood Hits	997	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	Q01201, Q6GTX7, Q9UEI7	Gene names	RELB
Domain Architecture
Description	Transcription factor RelB (I-Rel).

RELB_MOUSE
θ value	θ > 10 (rank : 1226)	NC score	0.050755 (rank : 917)
Query Neighborhood Hits	997	Target Neighborhood Hits	21	Shared Neighborhood Hits	6
SwissProt Accessions	Q04863	Gene names	Relb
Domain Architecture
Description	Transcription factor RelB.

REL_HUMAN
θ value	θ > 10 (rank : 1227)	NC score	0.052257 (rank : 868)
Query Neighborhood Hits	997	Target Neighborhood Hits	31	Shared Neighborhood Hits	9
SwissProt Accessions	Q04864, Q2PNZ7, Q6LDY0	Gene names	REL
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

REL_MOUSE
θ value	θ > 10 (rank : 1228)	NC score	0.054536 (rank : 826)
Query Neighborhood Hits	997	Target Neighborhood Hits	77	Shared Neighborhood Hits	21
SwissProt Accessions	P15307	Gene names	Rel
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

RET_HUMAN
θ value	θ > 10 (rank : 1229)	NC score	0.057112 (rank : 792)
Query Neighborhood Hits	997	Target Neighborhood Hits	873	Shared Neighborhood Hits	76
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RET_MOUSE
θ value	θ > 10 (rank : 1230)	NC score	0.057398 (rank : 785)
Query Neighborhood Hits	997	Target Neighborhood Hits	884	Shared Neighborhood Hits	79
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RIN3_MOUSE
θ value	θ > 10 (rank : 1231)	NC score	0.064642 (rank : 642)
Query Neighborhood Hits	997	Target Neighborhood Hits	239	Shared Neighborhood Hits	124
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RIPK1_HUMAN
θ value	θ > 10 (rank : 1232)	NC score	0.054333 (rank : 829)
Query Neighborhood Hits	997	Target Neighborhood Hits	891	Shared Neighborhood Hits	84
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

RIPK1_MOUSE
θ value	θ > 10 (rank : 1233)	NC score	0.052147 (rank : 873)
Query Neighborhood Hits	997	Target Neighborhood Hits	874	Shared Neighborhood Hits	85
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

RIPK2_HUMAN
θ value	θ > 10 (rank : 1234)	NC score	0.071956 (rank : 564)
Query Neighborhood Hits	997	Target Neighborhood Hits	774	Shared Neighborhood Hits	75
SwissProt Accessions	O43353, Q6UWF0	Gene names	RIPK2, CARDIAK, RICK, RIP2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme- associated kinase) (CARD-containing IL-1 beta ICE-kinase).

RIPK2_MOUSE
θ value	θ > 10 (rank : 1235)	NC score	0.066428 (rank : 613)
Query Neighborhood Hits	997	Target Neighborhood Hits	776	Shared Neighborhood Hits	74
SwissProt Accessions	P58801	Gene names	Ripk2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1).

RIPK3_HUMAN
θ value	θ > 10 (rank : 1236)	NC score	0.061973 (rank : 678)
Query Neighborhood Hits	997	Target Neighborhood Hits	828	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Y572	Gene names	RIPK3, RIP3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3).

RIPK3_MOUSE
θ value	θ > 10 (rank : 1237)	NC score	0.060914 (rank : 697)
Query Neighborhood Hits	997	Target Neighborhood Hits	867	Shared Neighborhood Hits	99
SwissProt Accessions	Q9QZL0	Gene names	Ripk3, Rip3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3).

RON_HUMAN
θ value	θ > 10 (rank : 1238)	NC score	0.057990 (rank : 769)
Query Neighborhood Hits	997	Target Neighborhood Hits	842	Shared Neighborhood Hits	81
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

RON_MOUSE
θ value	θ > 10 (rank : 1239)	NC score	0.058210 (rank : 767)
Query Neighborhood Hits	997	Target Neighborhood Hits	836	Shared Neighborhood Hits	78
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

ROR1_HUMAN
θ value	θ > 10 (rank : 1240)	NC score	0.060775 (rank : 702)
Query Neighborhood Hits	997	Target Neighborhood Hits	1018	Shared Neighborhood Hits	82
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

ROR1_MOUSE
θ value	θ > 10 (rank : 1241)	NC score	0.060746 (rank : 704)
Query Neighborhood Hits	997	Target Neighborhood Hits	1025	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Z139	Gene names	Ror1, Ntrkr1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1).

ROR2_HUMAN
θ value	θ > 10 (rank : 1242)	NC score	0.060552 (rank : 711)
Query Neighborhood Hits	997	Target Neighborhood Hits	1014	Shared Neighborhood Hits	83
SwissProt Accessions	Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61	Gene names	ROR2, NTRKR2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2).

ROR2_MOUSE
θ value	θ > 10 (rank : 1243)	NC score	0.061458 (rank : 684)
Query Neighborhood Hits	997	Target Neighborhood Hits	1000	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Z138	Gene names	Ror2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2).

ROS_HUMAN
θ value	θ > 10 (rank : 1244)	NC score	0.059290 (rank : 739)
Query Neighborhood Hits	997	Target Neighborhood Hits	907	Shared Neighborhood Hits	85
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

RP1L1_HUMAN
θ value	θ > 10 (rank : 1245)	NC score	0.076816 (rank : 524)
Query Neighborhood Hits	997	Target Neighborhood Hits	1072	Shared Neighborhood Hits	246
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

RPB1_HUMAN
θ value	θ > 10 (rank : 1246)	NC score	0.071705 (rank : 567)
Query Neighborhood Hits	997	Target Neighborhood Hits	362	Shared Neighborhood Hits	122
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	θ > 10 (rank : 1247)	NC score	0.071912 (rank : 566)
Query Neighborhood Hits	997	Target Neighborhood Hits	363	Shared Neighborhood Hits	125
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RTN4_HUMAN
θ value	θ > 10 (rank : 1248)	NC score	0.050609 (rank : 919)
Query Neighborhood Hits	997	Target Neighborhood Hits	357	Shared Neighborhood Hits	119
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

RYK_HUMAN
θ value	θ > 10 (rank : 1249)	NC score	0.059375 (rank : 737)
Query Neighborhood Hits	997	Target Neighborhood Hits	701	Shared Neighborhood Hits	69
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

RYK_MOUSE
θ value	θ > 10 (rank : 1250)	NC score	0.058961 (rank : 748)
Query Neighborhood Hits	997	Target Neighborhood Hits	715	Shared Neighborhood Hits	71
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

S23IP_MOUSE
θ value	θ > 10 (rank : 1251)	NC score	0.083403 (rank : 493)
Query Neighborhood Hits	997	Target Neighborhood Hits	363	Shared Neighborhood Hits	139
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

SAM14_HUMAN
θ value	θ > 10 (rank : 1252)	NC score	0.056190 (rank : 801)
Query Neighborhood Hits	997	Target Neighborhood Hits	81	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IZD0, Q8N2X0	Gene names	SAMD14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

SAM14_MOUSE
θ value	θ > 10 (rank : 1253)	NC score	0.058981 (rank : 747)
Query Neighborhood Hits	997	Target Neighborhood Hits	91	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K070, Q5SWB7, Q8BHE2, Q8C8N5	Gene names	Samd14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

SC24C_HUMAN
θ value	θ > 10 (rank : 1254)	NC score	0.081834 (rank : 500)
Query Neighborhood Hits	997	Target Neighborhood Hits	662	Shared Neighborhood Hits	235
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SELV_HUMAN
θ value	θ > 10 (rank : 1255)	NC score	0.077206 (rank : 519)
Query Neighborhood Hits	997	Target Neighborhood Hits	118	Shared Neighborhood Hits	68
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

SET1A_HUMAN
θ value	θ > 10 (rank : 1256)	NC score	0.110194 (rank : 389)
Query Neighborhood Hits	997	Target Neighborhood Hits	690	Shared Neighborhood Hits	210
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SETB1_MOUSE
θ value	θ > 10 (rank : 1257)	NC score	0.050500 (rank : 921)
Query Neighborhood Hits	997	Target Neighborhood Hits	150	Shared Neighborhood Hits	44
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SETD2_HUMAN
θ value	θ > 10 (rank : 1258)	NC score	0.052953 (rank : 854)
Query Neighborhood Hits	997	Target Neighborhood Hits	412	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SF01_HUMAN
θ value	θ > 10 (rank : 1259)	NC score	0.072376 (rank : 560)
Query Neighborhood Hits	997	Target Neighborhood Hits	287	Shared Neighborhood Hits	129
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SF01_MOUSE
θ value	θ > 10 (rank : 1260)	NC score	0.060616 (rank : 707)
Query Neighborhood Hits	997	Target Neighborhood Hits	240	Shared Neighborhood Hits	101
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SF3A2_HUMAN
θ value	θ > 10 (rank : 1261)	NC score	0.110470 (rank : 382)
Query Neighborhood Hits	997	Target Neighborhood Hits	263	Shared Neighborhood Hits	129
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SF3A2_MOUSE
θ value	θ > 10 (rank : 1262)	NC score	0.118274 (rank : 358)
Query Neighborhood Hits	997	Target Neighborhood Hits	247	Shared Neighborhood Hits	130
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SGIP1_HUMAN
θ value	θ > 10 (rank : 1263)	NC score	0.074316 (rank : 544)
Query Neighborhood Hits	997	Target Neighborhood Hits	198	Shared Neighborhood Hits	105
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SMAP1_HUMAN
θ value	θ > 10 (rank : 1264)	NC score	0.060595 (rank : 709)
Query Neighborhood Hits	997	Target Neighborhood Hits	98	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMAP1_MOUSE
θ value	θ > 10 (rank : 1265)	NC score	0.063531 (rank : 653)
Query Neighborhood Hits	997	Target Neighborhood Hits	120	Shared Neighborhood Hits	49
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMOO_HUMAN
θ value	θ > 10 (rank : 1266)	NC score	0.053122 (rank : 849)
Query Neighborhood Hits	997	Target Neighborhood Hits	391	Shared Neighborhood Hits	141
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

SMP1L_HUMAN
θ value	θ > 10 (rank : 1267)	NC score	0.058585 (rank : 760)
Query Neighborhood Hits	997	Target Neighborhood Hits	74	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMP1L_MOUSE
θ value	θ > 10 (rank : 1268)	NC score	0.056944 (rank : 794)
Query Neighborhood Hits	997	Target Neighborhood Hits	70	Shared Neighborhood Hits	34
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

SMR1_MOUSE
θ value	θ > 10 (rank : 1269)	NC score	0.075791 (rank : 529)
Query Neighborhood Hits	997	Target Neighborhood Hits	103	Shared Neighborhood Hits	66
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

SMR3A_HUMAN
θ value	θ > 10 (rank : 1270)	NC score	0.094012 (rank : 444)
Query Neighborhood Hits	997	Target Neighborhood Hits	93	Shared Neighborhood Hits	53
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

SPTA3_MOUSE
θ value	θ > 10 (rank : 1271)	NC score	0.068665 (rank : 593)
Query Neighborhood Hits	997	Target Neighborhood Hits	74	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D9T6, Q80ZS4, Q9D5L5, Q9DAF5	Gene names	Spata3, Tsarg1
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 3 (Testis spermatocyte apoptosis- related protein 1) (Testis and spermatogenesis cell-related protein 1) (mTSARG1).

SRC_HUMAN
θ value	θ > 10 (rank : 1272)	NC score	0.062306 (rank : 673)
Query Neighborhood Hits	997	Target Neighborhood Hits	1058	Shared Neighborhood Hits	125
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

SRC_MOUSE
θ value	θ > 10 (rank : 1273)	NC score	0.061860 (rank : 680)
Query Neighborhood Hits	997	Target Neighborhood Hits	1033	Shared Neighborhood Hits	124
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

SREC2_HUMAN
θ value	θ > 10 (rank : 1274)	NC score	0.063396 (rank : 655)
Query Neighborhood Hits	997	Target Neighborhood Hits	645	Shared Neighborhood Hits	129
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SREC2_MOUSE
θ value	θ > 10 (rank : 1275)	NC score	0.055801 (rank : 807)
Query Neighborhood Hits	997	Target Neighborhood Hits	605	Shared Neighborhood Hits	109
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SRMS_HUMAN
θ value	θ > 10 (rank : 1276)	NC score	0.057682 (rank : 777)
Query Neighborhood Hits	997	Target Neighborhood Hits	946	Shared Neighborhood Hits	95
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

SRMS_MOUSE
θ value	θ > 10 (rank : 1277)	NC score	0.057250 (rank : 790)
Query Neighborhood Hits	997	Target Neighborhood Hits	964	Shared Neighborhood Hits	97
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

STYK1_HUMAN
θ value	θ > 10 (rank : 1278)	NC score	0.050573 (rank : 920)
Query Neighborhood Hits	997	Target Neighborhood Hits	786	Shared Neighborhood Hits	75
SwissProt Accessions	Q6J9G0, Q9BXY2, Q9NSH1	Gene names	STYK1, NOK
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (Protein PK-unique).

SYNJ1_MOUSE
θ value	θ > 10 (rank : 1279)	NC score	0.074958 (rank : 540)
Query Neighborhood Hits	997	Target Neighborhood Hits	516	Shared Neighborhood Hits	213
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SYP2L_HUMAN
θ value	θ > 10 (rank : 1280)	NC score	0.065448 (rank : 633)
Query Neighborhood Hits	997	Target Neighborhood Hits	400	Shared Neighborhood Hits	151
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

T22D2_HUMAN
θ value	θ > 10 (rank : 1281)	NC score	0.078485 (rank : 513)
Query Neighborhood Hits	997	Target Neighborhood Hits	250	Shared Neighborhood Hits	107
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

TARA_MOUSE
θ value	θ > 10 (rank : 1282)	NC score	0.068061 (rank : 596)
Query Neighborhood Hits	997	Target Neighborhood Hits	1133	Shared Neighborhood Hits	197
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TCOF_HUMAN
θ value	θ > 10 (rank : 1283)	NC score	0.078401 (rank : 514)
Query Neighborhood Hits	997	Target Neighborhood Hits	543	Shared Neighborhood Hits	140
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TCOF_MOUSE
θ value	θ > 10 (rank : 1284)	NC score	0.093563 (rank : 447)
Query Neighborhood Hits	997	Target Neighborhood Hits	471	Shared Neighborhood Hits	143
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TCRG1_MOUSE
θ value	θ > 10 (rank : 1285)	NC score	0.060256 (rank : 719)
Query Neighborhood Hits	997	Target Neighborhood Hits	947	Shared Neighborhood Hits	164
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TEC_HUMAN
θ value	θ > 10 (rank : 1286)	NC score	0.061891 (rank : 679)
Query Neighborhood Hits	997	Target Neighborhood Hits	1006	Shared Neighborhood Hits	111
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TEC_MOUSE
θ value	θ > 10 (rank : 1287)	NC score	0.060994 (rank : 695)
Query Neighborhood Hits	997	Target Neighborhood Hits	1006	Shared Neighborhood Hits	111
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TESK1_HUMAN
θ value	θ > 10 (rank : 1288)	NC score	0.050766 (rank : 916)
Query Neighborhood Hits	997	Target Neighborhood Hits	864	Shared Neighborhood Hits	105
SwissProt Accessions	Q15569	Gene names	TESK1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

TESK1_MOUSE
θ value	θ > 10 (rank : 1289)	NC score	0.051047 (rank : 903)
Query Neighborhood Hits	997	Target Neighborhood Hits	862	Shared Neighborhood Hits	106
SwissProt Accessions	O70146, O70147	Gene names	Tesk1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

TESK2_HUMAN
θ value	θ > 10 (rank : 1290)	NC score	0.053312 (rank : 844)
Query Neighborhood Hits	997	Target Neighborhood Hits	851	Shared Neighborhood Hits	89
SwissProt Accessions	Q96S53, Q8N520, Q9Y3Q6	Gene names	TESK2
Domain Architecture
Description	Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2).

TESK2_MOUSE
θ value	θ > 10 (rank : 1291)	NC score	0.051031 (rank : 907)
Query Neighborhood Hits	997	Target Neighborhood Hits	833	Shared Neighborhood Hits	78
SwissProt Accessions	Q8VCT9	Gene names	Tesk2
Domain Architecture
Description	Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2).

TF65_HUMAN
θ value	θ > 10 (rank : 1292)	NC score	0.065480 (rank : 631)
Query Neighborhood Hits	997	Target Neighborhood Hits	115	Shared Neighborhood Hits	50
SwissProt Accessions	Q04206, Q6SLK1	Gene names	RELA, NFKB3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

TF65_MOUSE
θ value	θ > 10 (rank : 1293)	NC score	0.054091 (rank : 831)
Query Neighborhood Hits	997	Target Neighborhood Hits	66	Shared Neighborhood Hits	27
SwissProt Accessions	Q04207, Q62025	Gene names	Rela, Nfkb3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

TGON2_HUMAN
θ value	θ > 10 (rank : 1294)	NC score	0.083877 (rank : 491)
Query Neighborhood Hits	997	Target Neighborhood Hits	1037	Shared Neighborhood Hits	210
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TIE1_HUMAN
θ value	θ > 10 (rank : 1295)	NC score	0.068020 (rank : 598)
Query Neighborhood Hits	997	Target Neighborhood Hits	1241	Shared Neighborhood Hits	107
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE1_MOUSE
θ value	θ > 10 (rank : 1296)	NC score	0.068044 (rank : 597)
Query Neighborhood Hits	997	Target Neighborhood Hits	1266	Shared Neighborhood Hits	104
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE2_HUMAN
θ value	θ > 10 (rank : 1297)	NC score	0.067003 (rank : 608)
Query Neighborhood Hits	997	Target Neighborhood Hits	1192	Shared Neighborhood Hits	100
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TIE2_MOUSE
θ value	θ > 10 (rank : 1298)	NC score	0.067365 (rank : 604)
Query Neighborhood Hits	997	Target Neighborhood Hits	1204	Shared Neighborhood Hits	99
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

TM108_HUMAN
θ value	θ > 10 (rank : 1299)	NC score	0.068767 (rank : 591)
Query Neighborhood Hits	997	Target Neighborhood Hits	166	Shared Neighborhood Hits	85
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TMAP1_HUMAN
θ value	θ > 10 (rank : 1300)	NC score	0.066914 (rank : 609)
Query Neighborhood Hits	997	Target Neighborhood Hits	140	Shared Neighborhood Hits	72
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

TNK1_HUMAN
θ value	θ > 10 (rank : 1301)	NC score	0.065727 (rank : 628)
Query Neighborhood Hits	997	Target Neighborhood Hits	815	Shared Neighborhood Hits	93
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

TNK1_MOUSE
θ value	θ > 10 (rank : 1302)	NC score	0.062554 (rank : 672)
Query Neighborhood Hits	997	Target Neighborhood Hits	806	Shared Neighborhood Hits	87
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

TOPK_HUMAN
θ value	θ > 10 (rank : 1303)	NC score	0.051338 (rank : 894)
Query Neighborhood Hits	997	Target Neighborhood Hits	605	Shared Neighborhood Hits	60
SwissProt Accessions	Q96KB5, Q9NPD9, Q9NYL7, Q9NZK6	Gene names	PBK, TOPK
Domain Architecture	No domain graphic available
Description	T-lymphokine-activated killer cell-originated protein kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase) (Spermatogenesis-related protein kinase) (SPK) (MAPKK-like protein kinase) (Nori-3).

TRDN_HUMAN
θ value	θ > 10 (rank : 1304)	NC score	0.060958 (rank : 696)
Query Neighborhood Hits	997	Target Neighborhood Hits	542	Shared Neighborhood Hits	70
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TRPC3_MOUSE
θ value	θ > 10 (rank : 1305)	NC score	0.076317 (rank : 527)
Query Neighborhood Hits	997	Target Neighborhood Hits	131	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

TRPC6_MOUSE
θ value	θ > 10 (rank : 1306)	NC score	0.075393 (rank : 533)
Query Neighborhood Hits	997	Target Neighborhood Hits	171	Shared Neighborhood Hits	92
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPC7_HUMAN
θ value	θ > 10 (rank : 1307)	NC score	0.072021 (rank : 563)
Query Neighborhood Hits	997	Target Neighborhood Hits	123	Shared Neighborhood Hits	75
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

TRPC7_MOUSE
θ value	θ > 10 (rank : 1308)	NC score	0.070816 (rank : 576)
Query Neighborhood Hits	997	Target Neighborhood Hits	114	Shared Neighborhood Hits	74
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

TRPV3_HUMAN
θ value	θ > 10 (rank : 1309)	NC score	0.221658 (rank : 288)
Query Neighborhood Hits	997	Target Neighborhood Hits	198	Shared Neighborhood Hits	143
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPV3_MOUSE
θ value	θ > 10 (rank : 1310)	NC score	0.221150 (rank : 289)
Query Neighborhood Hits	997	Target Neighborhood Hits	188	Shared Neighborhood Hits	132
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV4_HUMAN
θ value	θ > 10 (rank : 1311)	NC score	0.115811 (rank : 363)
Query Neighborhood Hits	997	Target Neighborhood Hits	150	Shared Neighborhood Hits	93
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV4_MOUSE
θ value	θ > 10 (rank : 1312)	NC score	0.106127 (rank : 406)
Query Neighborhood Hits	997	Target Neighborhood Hits	117	Shared Neighborhood Hits	77
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TXK_HUMAN
θ value	θ > 10 (rank : 1313)	NC score	0.063643 (rank : 651)
Query Neighborhood Hits	997	Target Neighborhood Hits	971	Shared Neighborhood Hits	107
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

TXK_MOUSE
θ value	θ > 10 (rank : 1314)	NC score	0.063383 (rank : 656)
Query Neighborhood Hits	997	Target Neighborhood Hits	980	Shared Neighborhood Hits	111
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

TYK2_HUMAN
θ value	θ > 10 (rank : 1315)	NC score	0.051046 (rank : 904)
Query Neighborhood Hits	997	Target Neighborhood Hits	841	Shared Neighborhood Hits	78
SwissProt Accessions	P29597, Q6QB10, Q96CH0	Gene names	TYK2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

TYK2_MOUSE
θ value	θ > 10 (rank : 1316)	NC score	0.051438 (rank : 891)
Query Neighborhood Hits	997	Target Neighborhood Hits	850	Shared Neighborhood Hits	83
SwissProt Accessions	Q9R117, O88431, Q8VE41	Gene names	Tyk2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

TYRO3_HUMAN
θ value	θ > 10 (rank : 1317)	NC score	0.057399 (rank : 784)
Query Neighborhood Hits	997	Target Neighborhood Hits	995	Shared Neighborhood Hits	79
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

TYRO3_MOUSE
θ value	θ > 10 (rank : 1318)	NC score	0.057830 (rank : 776)
Query Neighborhood Hits	997	Target Neighborhood Hits	1007	Shared Neighborhood Hits	82
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

UFO_HUMAN
θ value	θ > 10 (rank : 1319)	NC score	0.058628 (rank : 758)
Query Neighborhood Hits	997	Target Neighborhood Hits	981	Shared Neighborhood Hits	88
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

UFO_MOUSE
θ value	θ > 10 (rank : 1320)	NC score	0.058924 (rank : 751)
Query Neighborhood Hits	997	Target Neighborhood Hits	988	Shared Neighborhood Hits	84
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

VCX1_HUMAN
θ value	θ > 10 (rank : 1321)	NC score	0.050192 (rank : 928)
Query Neighborhood Hits	997	Target Neighborhood Hits	129	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

VCX3_HUMAN
θ value	θ > 10 (rank : 1322)	NC score	0.056778 (rank : 796)
Query Neighborhood Hits	997	Target Neighborhood Hits	105	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

VCXC_HUMAN
θ value	θ > 10 (rank : 1323)	NC score	0.051044 (rank : 905)
Query Neighborhood Hits	997	Target Neighborhood Hits	139	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

WASF2_HUMAN
θ value	θ > 10 (rank : 1324)	NC score	0.083374 (rank : 494)
Query Neighborhood Hits	997	Target Neighborhood Hits	280	Shared Neighborhood Hits	161
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

WASF2_MOUSE
θ value	θ > 10 (rank : 1325)	NC score	0.099118 (rank : 425)
Query Neighborhood Hits	997	Target Neighborhood Hits	315	Shared Neighborhood Hits	182
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

WASF3_HUMAN
θ value	θ > 10 (rank : 1326)	NC score	0.067731 (rank : 601)
Query Neighborhood Hits	997	Target Neighborhood Hits	204	Shared Neighborhood Hits	107
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

WASF4_HUMAN
θ value	θ > 10 (rank : 1327)	NC score	0.081563 (rank : 502)
Query Neighborhood Hits	997	Target Neighborhood Hits	282	Shared Neighborhood Hits	157
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

WBS14_HUMAN
θ value	θ > 10 (rank : 1328)	NC score	0.074223 (rank : 545)
Query Neighborhood Hits	997	Target Neighborhood Hits	273	Shared Neighborhood Hits	132
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

WNK1_MOUSE
θ value	θ > 10 (rank : 1329)	NC score	0.050296 (rank : 924)
Query Neighborhood Hits	997	Target Neighborhood Hits	1179	Shared Neighborhood Hits	174
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

WNK4_HUMAN
θ value	θ > 10 (rank : 1330)	NC score	0.060386 (rank : 716)
Query Neighborhood Hits	997	Target Neighborhood Hits	1043	Shared Neighborhood Hits	206
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

WNK4_MOUSE
θ value	θ > 10 (rank : 1331)	NC score	0.050927 (rank : 911)
Query Neighborhood Hits	997	Target Neighborhood Hits	961	Shared Neighborhood Hits	159
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

YES_HUMAN
θ value	θ > 10 (rank : 1332)	NC score	0.063996 (rank : 646)
Query Neighborhood Hits	997	Target Neighborhood Hits	1059	Shared Neighborhood Hits	127
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

YES_MOUSE
θ value	θ > 10 (rank : 1333)	NC score	0.063795 (rank : 650)
Query Neighborhood Hits	997	Target Neighborhood Hits	1052	Shared Neighborhood Hits	125
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

ZAN_MOUSE
θ value	θ > 10 (rank : 1334)	NC score	0.053893 (rank : 833)
Query Neighborhood Hits	997	Target Neighborhood Hits	808	Shared Neighborhood Hits	84
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

ZAP70_HUMAN
θ value	θ > 10 (rank : 1335)	NC score	0.063072 (rank : 663)
Query Neighborhood Hits	997	Target Neighborhood Hits	893	Shared Neighborhood Hits	88
SwissProt Accessions	P43403	Gene names	ZAP70, SRK
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

ZAP70_MOUSE
θ value	θ > 10 (rank : 1336)	NC score	0.062049 (rank : 677)
Query Neighborhood Hits	997	Target Neighborhood Hits	905	Shared Neighborhood Hits	88
SwissProt Accessions	P43404	Gene names	Zap70, Srk, Zap-70
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

ZIM10_HUMAN
θ value	θ > 10 (rank : 1337)	NC score	0.058020 (rank : 768)
Query Neighborhood Hits	997	Target Neighborhood Hits	577	Shared Neighborhood Hits	208
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZIM10_MOUSE
θ value	θ > 10 (rank : 1338)	NC score	0.050833 (rank : 914)
Query Neighborhood Hits	997	Target Neighborhood Hits	430	Shared Neighborhood Hits	172
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZN207_HUMAN
θ value	θ > 10 (rank : 1339)	NC score	0.092331 (rank : 452)
Query Neighborhood Hits	997	Target Neighborhood Hits	326	Shared Neighborhood Hits	107
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

Hits sorted by NC score

CSKI1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	997	Target Neighborhood Hits	997	Shared Neighborhood Hits	997
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI1_MOUSE
NC score	0.976254 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	997	Target Neighborhood Hits	1031	Shared Neighborhood Hits	714
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI2_HUMAN
NC score	0.947646 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	997	Target Neighborhood Hits	747	Shared Neighborhood Hits	529
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CSKI2_MOUSE
NC score	0.942440 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	997	Target Neighborhood Hits	812	Shared Neighborhood Hits	520
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ANKS1_HUMAN
NC score	0.880761 (rank : 5)	θ value	2.58187e-47 (rank : 5)
Query Neighborhood Hits	997	Target Neighborhood Hits	438	Shared Neighborhood Hits	342
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ANKS1_MOUSE
NC score	0.872711 (rank : 6)	θ value	8.30557e-46 (rank : 6)
Query Neighborhood Hits	997	Target Neighborhood Hits	453	Shared Neighborhood Hits	348
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ANR29_HUMAN
NC score	0.868863 (rank : 7)	θ value	7.82807e-20 (rank : 45)
Query Neighborhood Hits	997	Target Neighborhood Hits	294	Shared Neighborhood Hits	284
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

PSD10_HUMAN
NC score	0.868499 (rank : 8)	θ value	5.07402e-19 (rank : 50)
Query Neighborhood Hits	997	Target Neighborhood Hits	301	Shared Neighborhood Hits	290
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

PSD10_MOUSE
NC score	0.866760 (rank : 9)	θ value	1.47631e-18 (rank : 52)
Query Neighborhood Hits	997	Target Neighborhood Hits	293	Shared Neighborhood Hits	286
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ANKR6_HUMAN
NC score	0.864860 (rank : 10)	θ value	3.75424e-22 (rank : 31)
Query Neighborhood Hits	997	Target Neighborhood Hits	439	Shared Neighborhood Hits	311
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ANR16_HUMAN
NC score	0.861089 (rank : 11)	θ value	7.32683e-18 (rank : 55)
Query Neighborhood Hits	997	Target Neighborhood Hits	286	Shared Neighborhood Hits	280
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

ANR50_HUMAN
NC score	0.860492 (rank : 12)	θ value	2.35151e-24 (rank : 19)
Query Neighborhood Hits	997	Target Neighborhood Hits	361	Shared Neighborhood Hits	301
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

TNKS1_HUMAN
NC score	0.859324 (rank : 13)	θ value	5.23862e-24 (rank : 20)
Query Neighborhood Hits	997	Target Neighborhood Hits	477	Shared Neighborhood Hits	377
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

ASB7_MOUSE
NC score	0.854979 (rank : 14)	θ value	5.99374e-20 (rank : 44)
Query Neighborhood Hits	997	Target Neighborhood Hits	296	Shared Neighborhood Hits	283
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_HUMAN
NC score	0.854966 (rank : 15)	θ value	7.82807e-20 (rank : 46)
Query Neighborhood Hits	997	Target Neighborhood Hits	296	Shared Neighborhood Hits	283
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ANR42_HUMAN
NC score	0.854300 (rank : 16)	θ value	1.09232e-21 (rank : 33)
Query Neighborhood Hits	997	Target Neighborhood Hits	284	Shared Neighborhood Hits	275
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

INVS_HUMAN
NC score	0.850967 (rank : 17)	θ value	1.80048e-24 (rank : 18)
Query Neighborhood Hits	997	Target Neighborhood Hits	455	Shared Neighborhood Hits	337
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

ASB10_MOUSE
NC score	0.850884 (rank : 18)	θ value	5.42112e-21 (rank : 36)
Query Neighborhood Hits	997	Target Neighborhood Hits	301	Shared Neighborhood Hits	285
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ANR42_MOUSE
NC score	0.850785 (rank : 19)	θ value	2.69047e-20 (rank : 42)
Query Neighborhood Hits	997	Target Neighborhood Hits	334	Shared Neighborhood Hits	281
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ASB10_HUMAN
NC score	0.850756 (rank : 20)	θ value	4.9032e-22 (rank : 32)
Query Neighborhood Hits	997	Target Neighborhood Hits	291	Shared Neighborhood Hits	280
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ASB3_MOUSE
NC score	0.850696 (rank : 21)	θ value	1.42661e-21 (rank : 34)
Query Neighborhood Hits	997	Target Neighborhood Hits	316	Shared Neighborhood Hits	290
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ASB3_HUMAN
NC score	0.850576 (rank : 22)	θ value	9.24701e-21 (rank : 38)
Query Neighborhood Hits	997	Target Neighborhood Hits	316	Shared Neighborhood Hits	293
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

TNKS2_HUMAN
NC score	0.849085 (rank : 23)	θ value	1.62847e-25 (rank : 15)
Query Neighborhood Hits	997	Target Neighborhood Hits	361	Shared Neighborhood Hits	313
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

ANR44_HUMAN
NC score	0.848554 (rank : 24)	θ value	9.54697e-26 (rank : 14)
Query Neighborhood Hits	997	Target Neighborhood Hits	318	Shared Neighborhood Hits	298
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ANR28_MOUSE
NC score	0.848299 (rank : 25)	θ value	5.06226e-27 (rank : 11)
Query Neighborhood Hits	997	Target Neighborhood Hits	314	Shared Neighborhood Hits	295
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

INVS_MOUSE
NC score	0.847411 (rank : 26)	θ value	6.84181e-24 (rank : 21)
Query Neighborhood Hits	997	Target Neighborhood Hits	609	Shared Neighborhood Hits	384
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

ANR28_HUMAN
NC score	0.847031 (rank : 27)	θ value	6.61148e-27 (rank : 13)
Query Neighborhood Hits	997	Target Neighborhood Hits	314	Shared Neighborhood Hits	297
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

FANK1_HUMAN
NC score	0.846407 (rank : 28)	θ value	3.07829e-16 (rank : 63)
Query Neighborhood Hits	997	Target Neighborhood Hits	326	Shared Neighborhood Hits	291
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

FANK1_MOUSE
NC score	0.845061 (rank : 29)	θ value	1.99529e-15 (rank : 73)
Query Neighborhood Hits	997	Target Neighborhood Hits	325	Shared Neighborhood Hits	292
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

ANK1_HUMAN
NC score	0.841609 (rank : 30)	θ value	3.50572e-28 (rank : 10)
Query Neighborhood Hits	997	Target Neighborhood Hits	416	Shared Neighborhood Hits	304
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANK1_MOUSE
NC score	0.840975 (rank : 31)	θ value	4.14116e-29 (rank : 7)
Query Neighborhood Hits	997	Target Neighborhood Hits	430	Shared Neighborhood Hits	307
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ANR52_MOUSE
NC score	0.840513 (rank : 32)	θ value	7.56453e-23 (rank : 28)
Query Neighborhood Hits	997	Target Neighborhood Hits	318	Shared Neighborhood Hits	297
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_HUMAN
NC score	0.840188 (rank : 33)	θ value	5.79196e-23 (rank : 25)
Query Neighborhood Hits	997	Target Neighborhood Hits	322	Shared Neighborhood Hits	297
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR39_HUMAN
NC score	0.838644 (rank : 34)	θ value	9.26847e-13 (rank : 109)
Query Neighborhood Hits	997	Target Neighborhood Hits	285	Shared Neighborhood Hits	280
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANR39_MOUSE
NC score	0.837293 (rank : 35)	θ value	6.00763e-12 (rank : 120)
Query Neighborhood Hits	997	Target Neighborhood Hits	284	Shared Neighborhood Hits	280
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANKR2_MOUSE
NC score	0.835549 (rank : 36)	θ value	2.88119e-14 (rank : 81)
Query Neighborhood Hits	997	Target Neighborhood Hits	312	Shared Neighborhood Hits	287
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ANK3_HUMAN
NC score	0.835376 (rank : 37)	θ value	6.61148e-27 (rank : 12)
Query Neighborhood Hits	997	Target Neighborhood Hits	853	Shared Neighborhood Hits	367
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ASB13_MOUSE
NC score	0.833022 (rank : 38)	θ value	8.10077e-17 (rank : 61)
Query Neighborhood Hits	997	Target Neighborhood Hits	293	Shared Neighborhood Hits	284
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ANKR2_HUMAN
NC score	0.832621 (rank : 39)	θ value	4.16044e-13 (rank : 103)
Query Neighborhood Hits	997	Target Neighborhood Hits	321	Shared Neighborhood Hits	288
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

ASB13_HUMAN
NC score	0.832514 (rank : 40)	θ value	6.20254e-17 (rank : 60)
Query Neighborhood Hits	997	Target Neighborhood Hits	293	Shared Neighborhood Hits	284
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ANR23_MOUSE
NC score	0.831752 (rank : 41)	θ value	1.33837e-11 (rank : 128)
Query Neighborhood Hits	997	Target Neighborhood Hits	296	Shared Neighborhood Hits	285
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

ASB2_HUMAN
NC score	0.831326 (rank : 42)	θ value	2.20605e-14 (rank : 80)
Query Neighborhood Hits	997	Target Neighborhood Hits	309	Shared Neighborhood Hits	286
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

BCL3_HUMAN
NC score	0.828975 (rank : 43)	θ value	1.29331e-14 (rank : 78)
Query Neighborhood Hits	997	Target Neighborhood Hits	324	Shared Neighborhood Hits	300
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

ANR23_HUMAN
NC score	0.827697 (rank : 44)	θ value	5.08577e-11 (rank : 140)
Query Neighborhood Hits	997	Target Neighborhood Hits	291	Shared Neighborhood Hits	285
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

BCL3_MOUSE
NC score	0.827400 (rank : 45)	θ value	2.88119e-14 (rank : 84)
Query Neighborhood Hits	997	Target Neighborhood Hits	388	Shared Neighborhood Hits	323
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

ANKS6_HUMAN
NC score	0.826742 (rank : 46)	θ value	5.25075e-16 (rank : 64)
Query Neighborhood Hits	997	Target Neighborhood Hits	411	Shared Neighborhood Hits	331
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ANKS6_MOUSE
NC score	0.826338 (rank : 47)	θ value	5.25075e-16 (rank : 65)
Query Neighborhood Hits	997	Target Neighborhood Hits	435	Shared Neighborhood Hits	341
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

PA2G6_MOUSE
NC score	0.826291 (rank : 48)	θ value	2.27762e-19 (rank : 47)
Query Neighborhood Hits	997	Target Neighborhood Hits	293	Shared Neighborhood Hits	279
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

MYPT1_MOUSE
NC score	0.826256 (rank : 49)	θ value	4.43474e-23 (rank : 24)
Query Neighborhood Hits	997	Target Neighborhood Hits	539	Shared Neighborhood Hits	305
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

ASB2_MOUSE
NC score	0.826093 (rank : 50)	θ value	5.25075e-16 (rank : 66)
Query Neighborhood Hits	997	Target Neighborhood Hits	321	Shared Neighborhood Hits	284
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

TRPA1_HUMAN
NC score	0.826052 (rank : 51)	θ value	2.97466e-19 (rank : 49)
Query Neighborhood Hits	997	Target Neighborhood Hits	339	Shared Neighborhood Hits	291
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

TRPA1_MOUSE
NC score	0.825918 (rank : 52)	θ value	3.28887e-18 (rank : 53)
Query Neighborhood Hits	997	Target Neighborhood Hits	343	Shared Neighborhood Hits	290
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

CDN2C_HUMAN
NC score	0.825735 (rank : 53)	θ value	2.88119e-14 (rank : 85)
Query Neighborhood Hits	997	Target Neighborhood Hits	262	Shared Neighborhood Hits	261
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

CDN2C_MOUSE
NC score	0.825045 (rank : 54)	θ value	1.42992e-13 (rank : 97)
Query Neighborhood Hits	997	Target Neighborhood Hits	270	Shared Neighborhood Hits	267
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

ANKR1_HUMAN
NC score	0.824558 (rank : 55)	θ value	3.89403e-11 (rank : 136)
Query Neighborhood Hits	997	Target Neighborhood Hits	308	Shared Neighborhood Hits	282
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ANKR1_MOUSE
NC score	0.822158 (rank : 56)	θ value	5.08577e-11 (rank : 138)
Query Neighborhood Hits	997	Target Neighborhood Hits	316	Shared Neighborhood Hits	286
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

GABP2_MOUSE
NC score	0.820694 (rank : 57)	θ value	4.59992e-12 (rank : 119)
Query Neighborhood Hits	997	Target Neighborhood Hits	429	Shared Neighborhood Hits	290
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

GABP2_HUMAN
NC score	0.818759 (rank : 58)	θ value	6.00763e-12 (rank : 121)
Query Neighborhood Hits	997	Target Neighborhood Hits	454	Shared Neighborhood Hits	288
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

GABP3_MOUSE
NC score	0.818173 (rank : 59)	θ value	1.133e-10 (rank : 145)
Query Neighborhood Hits	997	Target Neighborhood Hits	330	Shared Neighborhood Hits	277
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

MIB1_HUMAN
NC score	0.817423 (rank : 60)	θ value	1.6852e-22 (rank : 29)
Query Neighborhood Hits	997	Target Neighborhood Hits	470	Shared Neighborhood Hits	300
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
NC score	0.817045 (rank : 61)	θ value	1.6852e-22 (rank : 30)
Query Neighborhood Hits	997	Target Neighborhood Hits	471	Shared Neighborhood Hits	299
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

ASB8_MOUSE
NC score	0.816710 (rank : 62)	θ value	8.97725e-08 (rank : 183)
Query Neighborhood Hits	997	Target Neighborhood Hits	293	Shared Neighborhood Hits	281
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ANKS3_MOUSE
NC score	0.816176 (rank : 63)	θ value	1.09485e-13 (rank : 96)
Query Neighborhood Hits	997	Target Neighborhood Hits	355	Shared Neighborhood Hits	277
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ASB8_HUMAN
NC score	0.815912 (rank : 64)	θ value	1.17247e-07 (rank : 189)
Query Neighborhood Hits	997	Target Neighborhood Hits	294	Shared Neighborhood Hits	284
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

PP16A_MOUSE
NC score	0.815527 (rank : 65)	θ value	2.88119e-14 (rank : 87)
Query Neighborhood Hits	997	Target Neighborhood Hits	318	Shared Neighborhood Hits	288
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

ANKS3_HUMAN
NC score	0.814141 (rank : 66)	θ value	6.41864e-14 (rank : 93)
Query Neighborhood Hits	997	Target Neighborhood Hits	355	Shared Neighborhood Hits	282
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ASB16_MOUSE
NC score	0.811359 (rank : 67)	θ value	2.0648e-12 (rank : 111)
Query Neighborhood Hits	997	Target Neighborhood Hits	306	Shared Neighborhood Hits	280
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ANK2_HUMAN
NC score	0.811154 (rank : 68)	θ value	1.2049e-28 (rank : 8)
Query Neighborhood Hits	997	Target Neighborhood Hits	1615	Shared Neighborhood Hits	569
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

PP16B_HUMAN
NC score	0.809416 (rank : 69)	θ value	5.25075e-16 (rank : 69)
Query Neighborhood Hits	997	Target Neighborhood Hits	307	Shared Neighborhood Hits	281
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

ANR49_MOUSE
NC score	0.809366 (rank : 70)	θ value	3.41135e-07 (rank : 201)
Query Neighborhood Hits	997	Target Neighborhood Hits	285	Shared Neighborhood Hits	273
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

MYPT2_HUMAN
NC score	0.808976 (rank : 71)	θ value	2.97466e-19 (rank : 48)
Query Neighborhood Hits	997	Target Neighborhood Hits	707	Shared Neighborhood Hits	310
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

CDN2D_HUMAN
NC score	0.808577 (rank : 72)	θ value	2.98157e-11 (rank : 133)
Query Neighborhood Hits	997	Target Neighborhood Hits	268	Shared Neighborhood Hits	266
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

PP16A_HUMAN
NC score	0.808351 (rank : 73)	θ value	1.2105e-12 (rank : 110)
Query Neighborhood Hits	997	Target Neighborhood Hits	340	Shared Neighborhood Hits	294
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

PP16B_MOUSE
NC score	0.807637 (rank : 74)	θ value	1.38178e-16 (rank : 62)
Query Neighborhood Hits	997	Target Neighborhood Hits	302	Shared Neighborhood Hits	279
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

PA2G6_HUMAN
NC score	0.807295 (rank : 75)	θ value	2.98157e-11 (rank : 134)
Query Neighborhood Hits	997	Target Neighborhood Hits	284	Shared Neighborhood Hits	275
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ASB15_HUMAN
NC score	0.807139 (rank : 76)	θ value	4.91457e-14 (rank : 90)
Query Neighborhood Hits	997	Target Neighborhood Hits	305	Shared Neighborhood Hits	280
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

MIB2_HUMAN
NC score	0.806601 (rank : 77)	θ value	1.63225e-17 (rank : 57)
Query Neighborhood Hits	997	Target Neighborhood Hits	438	Shared Neighborhood Hits	292
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

ANKR5_MOUSE
NC score	0.806459 (rank : 78)	θ value	4.91457e-14 (rank : 89)
Query Neighborhood Hits	997	Target Neighborhood Hits	298	Shared Neighborhood Hits	284
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

MYPT1_HUMAN
NC score	0.805953 (rank : 79)	θ value	5.79196e-23 (rank : 26)
Query Neighborhood Hits	997	Target Neighborhood Hits	723	Shared Neighborhood Hits	307
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

MIB2_MOUSE
NC score	0.805277 (rank : 80)	θ value	1.13037e-18 (rank : 51)
Query Neighborhood Hits	997	Target Neighborhood Hits	409	Shared Neighborhood Hits	286
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

ANR49_HUMAN
NC score	0.804071 (rank : 81)	θ value	4.92598e-06 (rank : 229)
Query Neighborhood Hits	997	Target Neighborhood Hits	282	Shared Neighborhood Hits	273
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

IKBA_HUMAN
NC score	0.802245 (rank : 82)	θ value	5.43371e-13 (rank : 107)
Query Neighborhood Hits	997	Target Neighborhood Hits	280	Shared Neighborhood Hits	273
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

ANKR5_HUMAN
NC score	0.801935 (rank : 83)	θ value	5.08577e-11 (rank : 139)
Query Neighborhood Hits	997	Target Neighborhood Hits	297	Shared Neighborhood Hits	282
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ASB9_HUMAN
NC score	0.801292 (rank : 84)	θ value	2.88119e-14 (rank : 83)
Query Neighborhood Hits	997	Target Neighborhood Hits	267	Shared Neighborhood Hits	254
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

ASB16_HUMAN
NC score	0.800797 (rank : 85)	θ value	1.47974e-10 (rank : 146)
Query Neighborhood Hits	997	Target Neighborhood Hits	286	Shared Neighborhood Hits	270
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ASB15_MOUSE
NC score	0.800592 (rank : 86)	θ value	2.13179e-17 (rank : 58)
Query Neighborhood Hits	997	Target Neighborhood Hits	292	Shared Neighborhood Hits	271
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ASZ1_HUMAN
NC score	0.800322 (rank : 87)	θ value	2.28291e-11 (rank : 130)
Query Neighborhood Hits	997	Target Neighborhood Hits	341	Shared Neighborhood Hits	275
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ASB5_HUMAN
NC score	0.797456 (rank : 88)	θ value	3.18553e-13 (rank : 102)
Query Neighborhood Hits	997	Target Neighborhood Hits	283	Shared Neighborhood Hits	269
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

CDN2D_MOUSE
NC score	0.797451 (rank : 89)	θ value	1.80886e-08 (rank : 172)
Query Neighborhood Hits	997	Target Neighborhood Hits	267	Shared Neighborhood Hits	264
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ASB14_MOUSE
NC score	0.797240 (rank : 90)	θ value	4.16044e-13 (rank : 104)
Query Neighborhood Hits	997	Target Neighborhood Hits	293	Shared Neighborhood Hits	277
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ANRA2_HUMAN
NC score	0.796664 (rank : 91)	θ value	2.98157e-11 (rank : 132)
Query Neighborhood Hits	997	Target Neighborhood Hits	288	Shared Neighborhood Hits	272
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ASZ1_MOUSE
NC score	0.796058 (rank : 92)	θ value	1.38499e-08 (rank : 168)
Query Neighborhood Hits	997	Target Neighborhood Hits	319	Shared Neighborhood Hits	279
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ASB5_MOUSE
NC score	0.795641 (rank : 93)	θ value	9.90251e-15 (rank : 77)
Query Neighborhood Hits	997	Target Neighborhood Hits	266	Shared Neighborhood Hits	257
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ASB11_HUMAN
NC score	0.795500 (rank : 94)	θ value	2.43908e-13 (rank : 101)
Query Neighborhood Hits	997	Target Neighborhood Hits	271	Shared Neighborhood Hits	258
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ANKR7_HUMAN
NC score	0.794532 (rank : 95)	θ value	2.61198e-07 (rank : 196)
Query Neighborhood Hits	997	Target Neighborhood Hits	286	Shared Neighborhood Hits	278
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

ANRA2_MOUSE
NC score	0.793555 (rank : 96)	θ value	1.133e-10 (rank : 144)
Query Neighborhood Hits	997	Target Neighborhood Hits	287	Shared Neighborhood Hits	271
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ASB11_MOUSE
NC score	0.792417 (rank : 97)	θ value	3.89403e-11 (rank : 137)
Query Neighborhood Hits	997	Target Neighborhood Hits	271	Shared Neighborhood Hits	255
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ASB9_MOUSE
NC score	0.791954 (rank : 98)	θ value	8.38298e-14 (rank : 94)
Query Neighborhood Hits	997	Target Neighborhood Hits	257	Shared Neighborhood Hits	250
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

MTPN_MOUSE
NC score	0.791173 (rank : 99)	θ value	0.000461057 (rank : 283)
Query Neighborhood Hits	997	Target Neighborhood Hits	269	Shared Neighborhood Hits	264
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

IKBE_MOUSE
NC score	0.790846 (rank : 100)	θ value	2.13673e-09 (rank : 161)
Query Neighborhood Hits	997	Target Neighborhood Hits	308	Shared Neighborhood Hits	280
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

IKBA_MOUSE
NC score	0.790670 (rank : 101)	θ value	6.00763e-12 (rank : 122)
Query Neighborhood Hits	997	Target Neighborhood Hits	283	Shared Neighborhood Hits	274
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

EHMT1_HUMAN
NC score	0.790193 (rank : 102)	θ value	5.60996e-18 (rank : 54)
Query Neighborhood Hits	997	Target Neighborhood Hits	417	Shared Neighborhood Hits	315
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

CT086_HUMAN
NC score	0.789164 (rank : 103)	θ value	7.59969e-07 (rank : 214)
Query Neighborhood Hits	997	Target Neighborhood Hits	277	Shared Neighborhood Hits	272
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

ANR10_MOUSE
NC score	0.787409 (rank : 104)	θ value	1.25267e-09 (rank : 157)
Query Neighborhood Hits	997	Target Neighborhood Hits	273	Shared Neighborhood Hits	263
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

RFXK_HUMAN
NC score	0.787168 (rank : 105)	θ value	4.0297e-08 (rank : 180)
Query Neighborhood Hits	997	Target Neighborhood Hits	282	Shared Neighborhood Hits	266
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

ANR46_HUMAN
NC score	0.787121 (rank : 106)	θ value	1.69304e-06 (rank : 220)
Query Neighborhood Hits	997	Target Neighborhood Hits	281	Shared Neighborhood Hits	276
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ANR10_HUMAN
NC score	0.786881 (rank : 107)	θ value	4.0297e-08 (rank : 178)
Query Neighborhood Hits	997	Target Neighborhood Hits	289	Shared Neighborhood Hits	266
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

MTPN_HUMAN
NC score	0.786449 (rank : 108)	θ value	0.00134147 (rank : 295)
Query Neighborhood Hits	997	Target Neighborhood Hits	269	Shared Neighborhood Hits	264
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

AN36B_HUMAN
NC score	0.783293 (rank : 109)	θ value	1.74796e-11 (rank : 129)
Query Neighborhood Hits	997	Target Neighborhood Hits	294	Shared Neighborhood Hits	280
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

RN5A_HUMAN
NC score	0.783127 (rank : 110)	θ value	2.98157e-11 (rank : 135)
Query Neighborhood Hits	997	Target Neighborhood Hits	608	Shared Neighborhood Hits	306
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ANR46_MOUSE
NC score	0.782567 (rank : 111)	θ value	2.61198e-07 (rank : 197)
Query Neighborhood Hits	997	Target Neighborhood Hits	274	Shared Neighborhood Hits	269
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ASB4_HUMAN
NC score	0.780135 (rank : 112)	θ value	2.36244e-08 (rank : 174)
Query Neighborhood Hits	997	Target Neighborhood Hits	264	Shared Neighborhood Hits	258
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ASB4_MOUSE
NC score	0.779357 (rank : 113)	θ value	4.0297e-08 (rank : 179)
Query Neighborhood Hits	997	Target Neighborhood Hits	265	Shared Neighborhood Hits	259
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

EHMT2_HUMAN
NC score	0.778769 (rank : 114)	θ value	3.40345e-15 (rank : 75)
Query Neighborhood Hits	997	Target Neighborhood Hits	498	Shared Neighborhood Hits	321
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

BARD1_HUMAN
NC score	0.778581 (rank : 115)	θ value	7.84624e-12 (rank : 124)
Query Neighborhood Hits	997	Target Neighborhood Hits	427	Shared Neighborhood Hits	290
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ANR22_HUMAN
NC score	0.778405 (rank : 116)	θ value	4.1701e-05 (rank : 246)
Query Neighborhood Hits	997	Target Neighborhood Hits	243	Shared Neighborhood Hits	240
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

BARD1_MOUSE
NC score	0.776361 (rank : 117)	θ value	2.69671e-12 (rank : 114)
Query Neighborhood Hits	997	Target Neighborhood Hits	411	Shared Neighborhood Hits	286
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

EHMT2_MOUSE
NC score	0.775951 (rank : 118)	θ value	1.99529e-15 (rank : 72)
Query Neighborhood Hits	997	Target Neighborhood Hits	750	Shared Neighborhood Hits	416
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ASB12_MOUSE
NC score	0.775716 (rank : 119)	θ value	1.80886e-08 (rank : 171)
Query Neighborhood Hits	997	Target Neighborhood Hits	261	Shared Neighborhood Hits	258
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ACBD6_MOUSE
NC score	0.773226 (rank : 120)	θ value	6.87365e-08 (rank : 181)
Query Neighborhood Hits	997	Target Neighborhood Hits	305	Shared Neighborhood Hits	285
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

IKBE_HUMAN
NC score	0.772711 (rank : 121)	θ value	4.76016e-09 (rank : 165)
Query Neighborhood Hits	997	Target Neighborhood Hits	288	Shared Neighborhood Hits	271
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

ANR35_HUMAN
NC score	0.772556 (rank : 122)	θ value	2.60593e-15 (rank : 74)
Query Neighborhood Hits	997	Target Neighborhood Hits	784	Shared Neighborhood Hits	310
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

ASB12_HUMAN
NC score	0.771388 (rank : 123)	θ value	1.06045e-08 (rank : 167)
Query Neighborhood Hits	997	Target Neighborhood Hits	263	Shared Neighborhood Hits	262
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

RFXK_MOUSE
NC score	0.770749 (rank : 124)	θ value	1.29631e-06 (rank : 219)
Query Neighborhood Hits	997	Target Neighborhood Hits	273	Shared Neighborhood Hits	265
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

IKBB_MOUSE
NC score	0.770128 (rank : 125)	θ value	7.34386e-10 (rank : 156)
Query Neighborhood Hits	997	Target Neighborhood Hits	284	Shared Neighborhood Hits	276
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

ACBD6_HUMAN
NC score	0.769264 (rank : 126)	θ value	1.17247e-07 (rank : 187)
Query Neighborhood Hits	997	Target Neighborhood Hits	304	Shared Neighborhood Hits	285
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

IKBB_HUMAN
NC score	0.767282 (rank : 127)	θ value	5.62301e-10 (rank : 151)
Query Neighborhood Hits	997	Target Neighborhood Hits	284	Shared Neighborhood Hits	274
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

ANR32_HUMAN
NC score	0.762775 (rank : 128)	θ value	1.25267e-09 (rank : 158)
Query Neighborhood Hits	997	Target Neighborhood Hits	270	Shared Neighborhood Hits	257
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ASB1_HUMAN
NC score	0.762397 (rank : 129)	θ value	1.09739e-05 (rank : 234)
Query Neighborhood Hits	997	Target Neighborhood Hits	291	Shared Neighborhood Hits	271
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ASB1_MOUSE
NC score	0.762021 (rank : 130)	θ value	3.77169e-06 (rank : 228)
Query Neighborhood Hits	997	Target Neighborhood Hits	292	Shared Neighborhood Hits	271
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

POTE8_HUMAN
NC score	0.759517 (rank : 131)	θ value	1.68911e-14 (rank : 79)
Query Neighborhood Hits	997	Target Neighborhood Hits	337	Shared Neighborhood Hits	283
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

ZDH17_HUMAN
NC score	0.752098 (rank : 132)	θ value	7.0802e-21 (rank : 37)
Query Neighborhood Hits	997	Target Neighborhood Hits	334	Shared Neighborhood Hits	283
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

ANR19_HUMAN
NC score	0.751793 (rank : 133)	θ value	5.62301e-10 (rank : 150)
Query Neighborhood Hits	997	Target Neighborhood Hits	276	Shared Neighborhood Hits	272
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

USH1G_HUMAN
NC score	0.751574 (rank : 134)	θ value	1.63604e-09 (rank : 159)
Query Neighborhood Hits	997	Target Neighborhood Hits	267	Shared Neighborhood Hits	261
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

USH1G_MOUSE
NC score	0.751417 (rank : 135)	θ value	1.63604e-09 (rank : 160)
Query Neighborhood Hits	997	Target Neighborhood Hits	271	Shared Neighborhood Hits	261
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

ANR11_HUMAN
NC score	0.749129 (rank : 136)	θ value	2.88119e-14 (rank : 82)
Query Neighborhood Hits	997	Target Neighborhood Hits	1289	Shared Neighborhood Hits	426
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ANR32_MOUSE
NC score	0.748060 (rank : 137)	θ value	1.53129e-07 (rank : 192)
Query Neighborhood Hits	997	Target Neighborhood Hits	285	Shared Neighborhood Hits	257
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ZDH17_MOUSE
NC score	0.747682 (rank : 138)	θ value	1.2077e-20 (rank : 41)
Query Neighborhood Hits	997	Target Neighborhood Hits	328	Shared Neighborhood Hits	277
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

ANFY1_MOUSE
NC score	0.745191 (rank : 139)	θ value	6.41864e-14 (rank : 92)
Query Neighborhood Hits	997	Target Neighborhood Hits	480	Shared Neighborhood Hits	293
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANFY1_HUMAN
NC score	0.744006 (rank : 140)	θ value	2.43908e-13 (rank : 98)
Query Neighborhood Hits	997	Target Neighborhood Hits	480	Shared Neighborhood Hits	288
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANS4B_HUMAN
NC score	0.741390 (rank : 141)	θ value	3.41135e-07 (rank : 202)
Query Neighborhood Hits	997	Target Neighborhood Hits	289	Shared Neighborhood Hits	259
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

AN36A_HUMAN
NC score	0.740622 (rank : 142)	θ value	9.92553e-07 (rank : 215)
Query Neighborhood Hits	997	Target Neighborhood Hits	271	Shared Neighborhood Hits	268
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

RN5A_MOUSE
NC score	0.740126 (rank : 143)	θ value	2.0648e-12 (rank : 113)
Query Neighborhood Hits	997	Target Neighborhood Hits	899	Shared Neighborhood Hits	335
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

SHAN1_HUMAN
NC score	0.739106 (rank : 144)	θ value	3.64472e-09 (rank : 163)
Query Neighborhood Hits	997	Target Neighborhood Hits	1041	Shared Neighborhood Hits	505
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

ZDH13_MOUSE
NC score	0.737813 (rank : 145)	θ value	1.52774e-15 (rank : 71)
Query Neighborhood Hits	997	Target Neighborhood Hits	329	Shared Neighborhood Hits	283
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

ZDH13_HUMAN
NC score	0.736326 (rank : 146)	θ value	8.38298e-14 (rank : 95)
Query Neighborhood Hits	997	Target Neighborhood Hits	322	Shared Neighborhood Hits	279
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

CTTB2_HUMAN
NC score	0.733748 (rank : 147)	θ value	1.63225e-17 (rank : 56)
Query Neighborhood Hits	997	Target Neighborhood Hits	1061	Shared Neighborhood Hits	367
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

ANR15_HUMAN
NC score	0.732632 (rank : 148)	θ value	2.43908e-13 (rank : 99)
Query Neighborhood Hits	997	Target Neighborhood Hits	478	Shared Neighborhood Hits	294
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ANR41_HUMAN
NC score	0.732066 (rank : 149)	θ value	5.44631e-05 (rank : 254)
Query Neighborhood Hits	997	Target Neighborhood Hits	332	Shared Neighborhood Hits	284
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

ANR47_MOUSE
NC score	0.729014 (rank : 150)	θ value	4.59992e-12 (rank : 118)
Query Neighborhood Hits	997	Target Neighborhood Hits	350	Shared Neighborhood Hits	270
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ANS4B_MOUSE
NC score	0.728716 (rank : 151)	θ value	2.21117e-06 (rank : 221)
Query Neighborhood Hits	997	Target Neighborhood Hits	294	Shared Neighborhood Hits	256
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ANKY2_HUMAN
NC score	0.725517 (rank : 152)	θ value	4.45536e-07 (rank : 207)
Query Neighborhood Hits	997	Target Neighborhood Hits	306	Shared Neighborhood Hits	262
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR37_HUMAN
NC score	0.718118 (rank : 153)	θ value	2.44474e-05 (rank : 242)
Query Neighborhood Hits	997	Target Neighborhood Hits	247	Shared Neighborhood Hits	244
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

ANR21_HUMAN
NC score	0.714299 (rank : 154)	θ value	5.8054e-15 (rank : 76)
Query Neighborhood Hits	997	Target Neighborhood Hits	864	Shared Neighborhood Hits	306
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

POT15_HUMAN
NC score	0.713397 (rank : 155)	θ value	4.91457e-14 (rank : 91)
Query Neighborhood Hits	997	Target Neighborhood Hits	893	Shared Neighborhood Hits	306
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

NFKB1_HUMAN
NC score	0.711667 (rank : 156)	θ value	2.88119e-14 (rank : 86)
Query Neighborhood Hits	997	Target Neighborhood Hits	306	Shared Neighborhood Hits	276
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

NFKB1_MOUSE
NC score	0.710253 (rank : 157)	θ value	2.69671e-12 (rank : 115)
Query Neighborhood Hits	997	Target Neighborhood Hits	300	Shared Neighborhood Hits	273
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

ANR47_HUMAN
NC score	0.707521 (rank : 158)	θ value	4.76016e-09 (rank : 164)
Query Neighborhood Hits	997	Target Neighborhood Hits	369	Shared Neighborhood Hits	273
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ANKY2_MOUSE
NC score	0.704554 (rank : 159)	θ value	1.17247e-07 (rank : 188)
Query Neighborhood Hits	997	Target Neighborhood Hits	316	Shared Neighborhood Hits	264
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR12_HUMAN
NC score	0.703890 (rank : 160)	θ value	3.76295e-14 (rank : 88)
Query Neighborhood Hits	997	Target Neighborhood Hits	1081	Shared Neighborhood Hits	324
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

NFKB2_HUMAN
NC score	0.701829 (rank : 161)	θ value	6.64225e-11 (rank : 141)
Query Neighborhood Hits	997	Target Neighborhood Hits	325	Shared Neighborhood Hits	281
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

SNCAP_HUMAN
NC score	0.701613 (rank : 162)	θ value	0.000270298 (rank : 277)
Query Neighborhood Hits	997	Target Neighborhood Hits	313	Shared Neighborhood Hits	254
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

ANR37_MOUSE
NC score	0.701572 (rank : 163)	θ value	2.88788e-06 (rank : 226)
Query Neighborhood Hits	997	Target Neighborhood Hits	237	Shared Neighborhood Hits	234
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

BCOR_MOUSE
NC score	0.701084 (rank : 164)	θ value	1.53129e-07 (rank : 193)
Query Neighborhood Hits	997	Target Neighborhood Hits	521	Shared Neighborhood Hits	329
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

POT14_HUMAN
NC score	0.700590 (rank : 165)	θ value	1.02475e-11 (rank : 126)
Query Neighborhood Hits	997	Target Neighborhood Hits	403	Shared Neighborhood Hits	276
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

BCOR_HUMAN
NC score	0.694942 (rank : 166)	θ value	3.41135e-07 (rank : 203)
Query Neighborhood Hits	997	Target Neighborhood Hits	609	Shared Neighborhood Hits	353
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

KRIT1_MOUSE
NC score	0.693245 (rank : 167)	θ value	2.28291e-11 (rank : 131)
Query Neighborhood Hits	997	Target Neighborhood Hits	258	Shared Neighborhood Hits	229
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

ASB6_HUMAN
NC score	0.688293 (rank : 168)	θ value	0.00298849 (rank : 308)
Query Neighborhood Hits	997	Target Neighborhood Hits	256	Shared Neighborhood Hits	245
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ANR25_HUMAN
NC score	0.688212 (rank : 169)	θ value	7.34386e-10 (rank : 154)
Query Neighborhood Hits	997	Target Neighborhood Hits	350	Shared Neighborhood Hits	277
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

NFKB2_MOUSE
NC score	0.686088 (rank : 170)	θ value	1.9326e-10 (rank : 148)
Query Neighborhood Hits	997	Target Neighborhood Hits	326	Shared Neighborhood Hits	282
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ANR33_MOUSE
NC score	0.685114 (rank : 171)	θ value	9.92553e-07 (rank : 216)
Query Neighborhood Hits	997	Target Neighborhood Hits	225	Shared Neighborhood Hits	223
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

KRIT1_HUMAN
NC score	0.683739 (rank : 172)	θ value	6.00763e-12 (rank : 123)
Query Neighborhood Hits	997	Target Neighborhood Hits	258	Shared Neighborhood Hits	220
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

ASB6_MOUSE
NC score	0.682823 (rank : 173)	θ value	0.00298849 (rank : 309)
Query Neighborhood Hits	997	Target Neighborhood Hits	264	Shared Neighborhood Hits	243
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

CD2A1_MOUSE
NC score	0.679450 (rank : 174)	θ value	7.1131e-05 (rank : 258)
Query Neighborhood Hits	997	Target Neighborhood Hits	206	Shared Neighborhood Hits	204
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

ANR25_MOUSE
NC score	0.678965 (rank : 175)	θ value	2.79066e-09 (rank : 162)
Query Neighborhood Hits	997	Target Neighborhood Hits	398	Shared Neighborhood Hits	297
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

ANR38_HUMAN
NC score	0.672025 (rank : 176)	θ value	4.30538e-10 (rank : 149)
Query Neighborhood Hits	997	Target Neighborhood Hits	443	Shared Neighborhood Hits	262
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

OSBL1_HUMAN
NC score	0.661490 (rank : 177)	θ value	5.25075e-16 (rank : 67)
Query Neighborhood Hits	997	Target Neighborhood Hits	368	Shared Neighborhood Hits	280
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

POT22_HUMAN
NC score	0.660979 (rank : 178)	θ value	1.17247e-07 (rank : 190)
Query Neighborhood Hits	997	Target Neighborhood Hits	266	Shared Neighborhood Hits	255
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

ANR33_HUMAN
NC score	0.660810 (rank : 179)	θ value	0.000270298 (rank : 274)
Query Neighborhood Hits	997	Target Neighborhood Hits	215	Shared Neighborhood Hits	212
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

OSTF1_MOUSE
NC score	0.649616 (rank : 180)	θ value	1.80886e-08 (rank : 173)
Query Neighborhood Hits	997	Target Neighborhood Hits	467	Shared Neighborhood Hits	301
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

OSBL1_MOUSE
NC score	0.649311 (rank : 181)	θ value	5.25075e-16 (rank : 68)
Query Neighborhood Hits	997	Target Neighborhood Hits	336	Shared Neighborhood Hits	280
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

MPP8_HUMAN
NC score	0.648297 (rank : 182)	θ value	3.41135e-07 (rank : 206)
Query Neighborhood Hits	997	Target Neighborhood Hits	948	Shared Neighborhood Hits	298
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

ANR38_MOUSE
NC score	0.647917 (rank : 183)	θ value	7.34386e-10 (rank : 155)
Query Neighborhood Hits	997	Target Neighborhood Hits	512	Shared Neighborhood Hits	262
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

CLPB_MOUSE
NC score	0.644880 (rank : 184)	θ value	0.00175202 (rank : 299)
Query Neighborhood Hits	997	Target Neighborhood Hits	289	Shared Neighborhood Hits	258
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

A20A3_HUMAN
NC score	0.639350 (rank : 185)	θ value	4.0297e-08 (rank : 176)
Query Neighborhood Hits	997	Target Neighborhood Hits	692	Shared Neighborhood Hits	295
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A2_HUMAN
NC score	0.638626 (rank : 186)	θ value	1.80886e-08 (rank : 170)
Query Neighborhood Hits	997	Target Neighborhood Hits	716	Shared Neighborhood Hits	298
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

A20A1_HUMAN
NC score	0.637899 (rank : 187)	θ value	3.08544e-08 (rank : 175)
Query Neighborhood Hits	997	Target Neighborhood Hits	698	Shared Neighborhood Hits	292
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

CDN2B_MOUSE
NC score	0.636058 (rank : 188)	θ value	0.00869519 (rank : 331)
Query Neighborhood Hits	997	Target Neighborhood Hits	201	Shared Neighborhood Hits	199
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

A20A4_HUMAN
NC score	0.634711 (rank : 189)	θ value	4.0297e-08 (rank : 177)
Query Neighborhood Hits	997	Target Neighborhood Hits	710	Shared Neighborhood Hits	296
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

OSTF1_HUMAN
NC score	0.632259 (rank : 190)	θ value	8.97725e-08 (rank : 185)
Query Neighborhood Hits	997	Target Neighborhood Hits	466	Shared Neighborhood Hits	299
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

RAI14_HUMAN
NC score	0.630255 (rank : 191)	θ value	1.2077e-20 (rank : 39)
Query Neighborhood Hits	997	Target Neighborhood Hits	1367	Shared Neighborhood Hits	355
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

CD2A1_HUMAN
NC score	0.607489 (rank : 192)	θ value	0.00509761 (rank : 322)
Query Neighborhood Hits	997	Target Neighborhood Hits	196	Shared Neighborhood Hits	193
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

ANR18_HUMAN
NC score	0.601388 (rank : 193)	θ value	2.43908e-13 (rank : 100)
Query Neighborhood Hits	997	Target Neighborhood Hits	1106	Shared Neighborhood Hits	311
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

RAI14_MOUSE
NC score	0.598953 (rank : 194)	θ value	1.2077e-20 (rank : 40)
Query Neighborhood Hits	997	Target Neighborhood Hits	1505	Shared Neighborhood Hits	362
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

ANR45_MOUSE
NC score	0.598431 (rank : 195)	θ value	0.000461057 (rank : 282)
Query Neighborhood Hits	997	Target Neighborhood Hits	204	Shared Neighborhood Hits	189
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ANR43_HUMAN
NC score	0.591098 (rank : 196)	θ value	0.0113563 (rank : 337)
Query Neighborhood Hits	997	Target Neighborhood Hits	209	Shared Neighborhood Hits	202
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

ANR43_MOUSE
NC score	0.590241 (rank : 197)	θ value	0.00390308 (rank : 315)
Query Neighborhood Hits	997	Target Neighborhood Hits	214	Shared Neighborhood Hits	204
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

CDN2B_HUMAN
NC score	0.589217 (rank : 198)	θ value	0.00390308 (rank : 317)
Query Neighborhood Hits	997	Target Neighborhood Hits	196	Shared Neighborhood Hits	196
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

HECD1_HUMAN
NC score	0.588336 (rank : 199)	θ value	3.41135e-07 (rank : 205)
Query Neighborhood Hits	997	Target Neighborhood Hits	371	Shared Neighborhood Hits	277
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

ANKK1_HUMAN
NC score	0.581495 (rank : 200)	θ value	4.73814e-25 (rank : 16)
Query Neighborhood Hits	997	Target Neighborhood Hits	1075	Shared Neighborhood Hits	352
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

RIPK4_HUMAN
NC score	0.579381 (rank : 201)	θ value	2.68423e-28 (rank : 9)
Query Neighborhood Hits	997	Target Neighborhood Hits	1094	Shared Neighborhood Hits	359
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

AN30A_HUMAN
NC score	0.573757 (rank : 202)	θ value	5.43371e-13 (rank : 106)
Query Neighborhood Hits	997	Target Neighborhood Hits	1119	Shared Neighborhood Hits	337
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

IASPP_HUMAN
NC score	0.573541 (rank : 203)	θ value	0.0193708 (rank : 353)
Query Neighborhood Hits	997	Target Neighborhood Hits	688	Shared Neighborhood Hits	417
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ABTB2_HUMAN
NC score	0.572859 (rank : 204)	θ value	2.61198e-07 (rank : 195)
Query Neighborhood Hits	997	Target Neighborhood Hits	391	Shared Neighborhood Hits	237
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ANKK1_MOUSE
NC score	0.568004 (rank : 205)	θ value	6.18819e-25 (rank : 17)
Query Neighborhood Hits	997	Target Neighborhood Hits	1072	Shared Neighborhood Hits	350
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

ASPP2_HUMAN
NC score	0.566568 (rank : 206)	θ value	7.59969e-07 (rank : 213)
Query Neighborhood Hits	997	Target Neighborhood Hits	1156	Shared Neighborhood Hits	412
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

ASPP1_HUMAN
NC score	0.562044 (rank : 207)	θ value	3.19293e-05 (rank : 244)
Query Neighborhood Hits	997	Target Neighborhood Hits	956	Shared Neighborhood Hits	387
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ABTB2_MOUSE
NC score	0.561338 (rank : 208)	θ value	1.17247e-07 (rank : 186)
Query Neighborhood Hits	997	Target Neighborhood Hits	414	Shared Neighborhood Hits	237
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

CLPB_HUMAN
NC score	0.557843 (rank : 209)	θ value	0.0431538 (rank : 380)
Query Neighborhood Hits	997	Target Neighborhood Hits	265	Shared Neighborhood Hits	234
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

ASPP1_MOUSE
NC score	0.557324 (rank : 210)	θ value	1.87187e-05 (rank : 238)
Query Neighborhood Hits	997	Target Neighborhood Hits	1244	Shared Neighborhood Hits	491
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ILK2_HUMAN
NC score	0.554648 (rank : 211)	θ value	3.52202e-12 (rank : 117)
Query Neighborhood Hits	997	Target Neighborhood Hits	848	Shared Neighborhood Hits	328
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

NUD12_MOUSE
NC score	0.553421 (rank : 212)	θ value	0.00509761 (rank : 324)
Query Neighborhood Hits	997	Target Neighborhood Hits	243	Shared Neighborhood Hits	219
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

ANR45_HUMAN
NC score	0.543651 (rank : 213)	θ value	θ > 10 (rank : 1020)
Query Neighborhood Hits	997	Target Neighborhood Hits	201	Shared Neighborhood Hits	185
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

IASPP_MOUSE
NC score	0.537621 (rank : 214)	θ value	7.1131e-05 (rank : 259)
Query Neighborhood Hits	997	Target Neighborhood Hits	1024	Shared Neighborhood Hits	512
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ILK1_HUMAN
NC score	0.537558 (rank : 215)	θ value	3.52202e-12 (rank : 116)
Query Neighborhood Hits	997	Target Neighborhood Hits	857	Shared Neighborhood Hits	328
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK_MOUSE
NC score	0.536725 (rank : 216)	θ value	2.0648e-12 (rank : 112)
Query Neighborhood Hits	997	Target Neighborhood Hits	858	Shared Neighborhood Hits	328
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

ANR40_HUMAN
NC score	0.534306 (rank : 217)	θ value	8.99809 (rank : 924)
Query Neighborhood Hits	997	Target Neighborhood Hits	224	Shared Neighborhood Hits	213
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

CENB5_HUMAN
NC score	0.533673 (rank : 218)	θ value	1.87187e-05 (rank : 240)
Query Neighborhood Hits	997	Target Neighborhood Hits	395	Shared Neighborhood Hits	271
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

ANR40_MOUSE
NC score	0.531839 (rank : 219)	θ value	8.99809 (rank : 925)
Query Neighborhood Hits	997	Target Neighborhood Hits	228	Shared Neighborhood Hits	214
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

TRPV6_MOUSE
NC score	0.531366 (rank : 220)	θ value	4.1701e-05 (rank : 253)
Query Neighborhood Hits	997	Target Neighborhood Hits	284	Shared Neighborhood Hits	254
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

AN13B_MOUSE
NC score	0.527874 (rank : 221)	θ value	2.88788e-06 (rank : 225)
Query Neighborhood Hits	997	Target Neighborhood Hits	276	Shared Neighborhood Hits	254
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13B_HUMAN
NC score	0.527099 (rank : 222)	θ value	2.88788e-06 (rank : 224)
Query Neighborhood Hits	997	Target Neighborhood Hits	265	Shared Neighborhood Hits	253
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

CENB1_HUMAN
NC score	0.523272 (rank : 223)	θ value	0.0252991 (rank : 360)
Query Neighborhood Hits	997	Target Neighborhood Hits	383	Shared Neighborhood Hits	270
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CENB2_HUMAN
NC score	0.520129 (rank : 224)	θ value	4.1701e-05 (rank : 247)
Query Neighborhood Hits	997	Target Neighborhood Hits	425	Shared Neighborhood Hits	262
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

ANKY1_HUMAN
NC score	0.519000 (rank : 225)	θ value	0.21417 (rank : 447)
Query Neighborhood Hits	997	Target Neighborhood Hits	248	Shared Neighborhood Hits	209
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

NUD12_HUMAN
NC score	0.516207 (rank : 226)	θ value	0.0431538 (rank : 386)
Query Neighborhood Hits	997	Target Neighborhood Hits	222	Shared Neighborhood Hits	198
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

ASB14_HUMAN
NC score	0.513011 (rank : 227)	θ value	0.163984 (rank : 433)
Query Neighborhood Hits	997	Target Neighborhood Hits	187	Shared Neighborhood Hits	175
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

AN13C_HUMAN
NC score	0.512419 (rank : 228)	θ value	0.00509761 (rank : 321)
Query Neighborhood Hits	997	Target Neighborhood Hits	241	Shared Neighborhood Hits	234
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

GLSL_HUMAN
NC score	0.507678 (rank : 229)	θ value	0.00175202 (rank : 302)
Query Neighborhood Hits	997	Target Neighborhood Hits	211	Shared Neighborhood Hits	202
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

GLSL_MOUSE
NC score	0.503638 (rank : 230)	θ value	0.00102713 (rank : 290)
Query Neighborhood Hits	997	Target Neighborhood Hits	212	Shared Neighborhood Hits	202
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

AN13C_MOUSE
NC score	0.503436 (rank : 231)	θ value	0.00298849 (rank : 307)
Query Neighborhood Hits	997	Target Neighborhood Hits	242	Shared Neighborhood Hits	232
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

GIT2_MOUSE
NC score	0.499596 (rank : 232)	θ value	0.000158464 (rank : 271)
Query Neighborhood Hits	997	Target Neighborhood Hits	323	Shared Neighborhood Hits	260
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

UACA_HUMAN
NC score	0.488484 (rank : 233)	θ value	1.02475e-11 (rank : 127)
Query Neighborhood Hits	997	Target Neighborhood Hits	1622	Shared Neighborhood Hits	348
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

TRPV5_MOUSE
NC score	0.484927 (rank : 234)	θ value	2.44474e-05 (rank : 243)
Query Neighborhood Hits	997	Target Neighborhood Hits	278	Shared Neighborhood Hits	246
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

GIT1_MOUSE
NC score	0.483497 (rank : 235)	θ value	4.1701e-05 (rank : 251)
Query Neighborhood Hits	997	Target Neighborhood Hits	341	Shared Neighborhood Hits	251
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

GIT1_HUMAN
NC score	0.482616 (rank : 236)	θ value	4.1701e-05 (rank : 250)
Query Neighborhood Hits	997	Target Neighborhood Hits	336	Shared Neighborhood Hits	252
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

TNI3K_HUMAN
NC score	0.470942 (rank : 237)	θ value	5.79196e-23 (rank : 27)
Query Neighborhood Hits	997	Target Neighborhood Hits	1084	Shared Neighborhood Hits	350
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

CT012_MOUSE
NC score	0.467774 (rank : 238)	θ value	1.87187e-05 (rank : 241)
Query Neighborhood Hits	997	Target Neighborhood Hits	229	Shared Neighborhood Hits	183
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

DDFL1_MOUSE
NC score	0.467543 (rank : 239)	θ value	0.00020696 (rank : 272)
Query Neighborhood Hits	997	Target Neighborhood Hits	324	Shared Neighborhood Hits	257
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

GIT2_HUMAN
NC score	0.465564 (rank : 240)	θ value	9.29e-05 (rank : 263)
Query Neighborhood Hits	997	Target Neighborhood Hits	381	Shared Neighborhood Hits	255
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

TNI3K_MOUSE
NC score	0.465058 (rank : 241)	θ value	2.43343e-21 (rank : 35)
Query Neighborhood Hits	997	Target Neighborhood Hits	1079	Shared Neighborhood Hits	350
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

AN13A_HUMAN
NC score	0.464227 (rank : 242)	θ value	8.40245e-06 (rank : 231)
Query Neighborhood Hits	997	Target Neighborhood Hits	243	Shared Neighborhood Hits	223
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

GLSK_HUMAN
NC score	0.463760 (rank : 243)	θ value	0.0431538 (rank : 383)
Query Neighborhood Hits	997	Target Neighborhood Hits	204	Shared Neighborhood Hits	189
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

UACA_MOUSE
NC score	0.463294 (rank : 244)	θ value	1.47974e-10 (rank : 147)
Query Neighborhood Hits	997	Target Neighborhood Hits	1620	Shared Neighborhood Hits	351
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

NOTC4_MOUSE
NC score	0.456936 (rank : 245)	θ value	6.85773e-16 (rank : 70)
Query Neighborhood Hits	997	Target Neighborhood Hits	872	Shared Neighborhood Hits	313
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC4_HUMAN
NC score	0.452894 (rank : 246)	θ value	4.74913e-17 (rank : 59)
Query Neighborhood Hits	997	Target Neighborhood Hits	905	Shared Neighborhood Hits	328
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

TRPV6_HUMAN
NC score	0.447656 (rank : 247)	θ value	0.00509761 (rank : 325)
Query Neighborhood Hits	997	Target Neighborhood Hits	262	Shared Neighborhood Hits	225
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

TRPV5_HUMAN
NC score	0.443646 (rank : 248)	θ value	0.125558 (rank : 432)
Query Neighborhood Hits	997	Target Neighborhood Hits	261	Shared Neighborhood Hits	224
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

ANR26_MOUSE
NC score	0.443020 (rank : 249)	θ value	6.87365e-08 (rank : 182)
Query Neighborhood Hits	997	Target Neighborhood Hits	1554	Shared Neighborhood Hits	344
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

AN13A_MOUSE
NC score	0.440924 (rank : 250)	θ value	7.1131e-05 (rank : 257)
Query Neighborhood Hits	997	Target Neighborhood Hits	226	Shared Neighborhood Hits	214
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

CT012_HUMAN
NC score	0.425448 (rank : 251)	θ value	0.00175202 (rank : 300)
Query Neighborhood Hits	997	Target Neighborhood Hits	205	Shared Neighborhood Hits	166
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

ANR26_HUMAN
NC score	0.423764 (rank : 252)	θ value	1.53129e-07 (rank : 191)
Query Neighborhood Hits	997	Target Neighborhood Hits	1614	Shared Neighborhood Hits	345
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

DAPK1_MOUSE
NC score	0.416437 (rank : 253)	θ value	1.16704e-23 (rank : 22)
Query Neighborhood Hits	997	Target Neighborhood Hits	1138	Shared Neighborhood Hits	356
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

NOTC3_MOUSE
NC score	0.414478 (rank : 254)	θ value	7.09661e-13 (rank : 108)
Query Neighborhood Hits	997	Target Neighborhood Hits	975	Shared Neighborhood Hits	356
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

DDEF2_HUMAN
NC score	0.414253 (rank : 255)	θ value	4.1701e-05 (rank : 248)
Query Neighborhood Hits	997	Target Neighborhood Hits	599	Shared Neighborhood Hits	350
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

NOTC3_HUMAN
NC score	0.414127 (rank : 256)	θ value	4.16044e-13 (rank : 105)
Query Neighborhood Hits	997	Target Neighborhood Hits	1062	Shared Neighborhood Hits	385
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

TEX14_HUMAN
NC score	0.413700 (rank : 257)	θ value	0.00228821 (rank : 305)
Query Neighborhood Hits	997	Target Neighborhood Hits	1103	Shared Neighborhood Hits	333
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TEX14_MOUSE
NC score	0.411050 (rank : 258)	θ value	0.000602161 (rank : 285)
Query Neighborhood Hits	997	Target Neighborhood Hits	1333	Shared Neighborhood Hits	337
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

DDEF2_MOUSE
NC score	0.410263 (rank : 259)	θ value	4.1701e-05 (rank : 249)
Query Neighborhood Hits	997	Target Neighborhood Hits	625	Shared Neighborhood Hits	357
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

NOTC2_HUMAN
NC score	0.409594 (rank : 260)	θ value	6.64225e-11 (rank : 142)
Query Neighborhood Hits	997	Target Neighborhood Hits	1113	Shared Neighborhood Hits	406
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

DAPK1_HUMAN
NC score	0.408220 (rank : 261)	θ value	1.99067e-23 (rank : 23)
Query Neighborhood Hits	997	Target Neighborhood Hits	1130	Shared Neighborhood Hits	351
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

NOTC1_HUMAN
NC score	0.406321 (rank : 262)	θ value	7.84624e-12 (rank : 125)
Query Neighborhood Hits	997	Target Neighborhood Hits	906	Shared Neighborhood Hits	315
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_MOUSE
NC score	0.405713 (rank : 263)	θ value	8.67504e-11 (rank : 143)
Query Neighborhood Hits	997	Target Neighborhood Hits	1069	Shared Neighborhood Hits	380
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

DDFL1_HUMAN
NC score	0.378042 (rank : 264)	θ value	0.00175202 (rank : 301)
Query Neighborhood Hits	997	Target Neighborhood Hits	353	Shared Neighborhood Hits	254
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DGKZ_HUMAN
NC score	0.368429 (rank : 265)	θ value	0.00298849 (rank : 311)
Query Neighborhood Hits	997	Target Neighborhood Hits	551	Shared Neighborhood Hits	221
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

CENG1_MOUSE
NC score	0.354254 (rank : 266)	θ value	0.00390308 (rank : 318)
Query Neighborhood Hits	997	Target Neighborhood Hits	531	Shared Neighborhood Hits	307
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

DGKZ_MOUSE
NC score	0.351129 (rank : 267)	θ value	0.00665767 (rank : 328)
Query Neighborhood Hits	997	Target Neighborhood Hits	542	Shared Neighborhood Hits	208
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

DGKI_HUMAN
NC score	0.350742 (rank : 268)	θ value	8.40245e-06 (rank : 232)
Query Neighborhood Hits	997	Target Neighborhood Hits	609	Shared Neighborhood Hits	223
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

CENG1_HUMAN
NC score	0.350721 (rank : 269)	θ value	0.00869519 (rank : 332)
Query Neighborhood Hits	997	Target Neighborhood Hits	544	Shared Neighborhood Hits	307
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

NOTC1_MOUSE
NC score	0.347781 (rank : 270)	θ value	5.62301e-10 (rank : 153)
Query Neighborhood Hits	997	Target Neighborhood Hits	916	Shared Neighborhood Hits	300
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

CENG2_HUMAN
NC score	0.338955 (rank : 271)	θ value	0.00298849 (rank : 310)
Query Neighborhood Hits	997	Target Neighborhood Hits	471	Shared Neighborhood Hits	263
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

ANKZ1_MOUSE
NC score	0.336812 (rank : 272)	θ value	0.21417 (rank : 449)
Query Neighborhood Hits	997	Target Neighborhood Hits	208	Shared Neighborhood Hits	155
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

CENG2_MOUSE
NC score	0.336039 (rank : 273)	θ value	0.00665767 (rank : 327)
Query Neighborhood Hits	997	Target Neighborhood Hits	463	Shared Neighborhood Hits	260
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

DDEF1_MOUSE
NC score	0.327213 (rank : 274)	θ value	0.00035302 (rank : 279)
Query Neighborhood Hits	997	Target Neighborhood Hits	592	Shared Neighborhood Hits	300
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

IKBL_HUMAN
NC score	0.323145 (rank : 275)	θ value	0.21417 (rank : 454)
Query Neighborhood Hits	997	Target Neighborhood Hits	168	Shared Neighborhood Hits	139
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

ANKZ1_HUMAN
NC score	0.318360 (rank : 276)	θ value	0.21417 (rank : 448)
Query Neighborhood Hits	997	Target Neighborhood Hits	236	Shared Neighborhood Hits	162
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

IKBL_MOUSE
NC score	0.315475 (rank : 277)	θ value	0.21417 (rank : 455)
Query Neighborhood Hits	997	Target Neighborhood Hits	196	Shared Neighborhood Hits	139
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

CENG3_MOUSE
NC score	0.307801 (rank : 278)	θ value	5.27518 (rank : 811)
Query Neighborhood Hits	997	Target Neighborhood Hits	467	Shared Neighborhood Hits	242
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_HUMAN
NC score	0.307768 (rank : 279)	θ value	5.27518 (rank : 810)
Query Neighborhood Hits	997	Target Neighborhood Hits	455	Shared Neighborhood Hits	243
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CLR59_HUMAN
NC score	0.305182 (rank : 280)	θ value	0.0431538 (rank : 381)
Query Neighborhood Hits	997	Target Neighborhood Hits	163	Shared Neighborhood Hits	143
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

ABTB1_MOUSE
NC score	0.272844 (rank : 281)	θ value	θ > 10 (rank : 1004)
Query Neighborhood Hits	997	Target Neighborhood Hits	349	Shared Neighborhood Hits	180
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

RSNL2_HUMAN
NC score	0.261271 (rank : 282)	θ value	4.1701e-05 (rank : 252)
Query Neighborhood Hits	997	Target Neighborhood Hits	136	Shared Neighborhood Hits	115
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

ANKR9_MOUSE
NC score	0.257839 (rank : 283)	θ value	8.99809 (rank : 923)
Query Neighborhood Hits	997	Target Neighborhood Hits	120	Shared Neighborhood Hits	116
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

BAT4_MOUSE
NC score	0.242064 (rank : 284)	θ value	θ > 10 (rank : 1034)
Query Neighborhood Hits	997	Target Neighborhood Hits	171	Shared Neighborhood Hits	125
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

TRPV1_MOUSE
NC score	0.237067 (rank : 285)	θ value	0.00228821 (rank : 306)
Query Neighborhood Hits	997	Target Neighborhood Hits	189	Shared Neighborhood Hits	155
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

ABTB1_HUMAN
NC score	0.231703 (rank : 286)	θ value	θ > 10 (rank : 1003)
Query Neighborhood Hits	997	Target Neighborhood Hits	325	Shared Neighborhood Hits	164
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

RSNL2_MOUSE
NC score	0.221718 (rank : 287)	θ value	0.00134147 (rank : 296)
Query Neighborhood Hits	997	Target Neighborhood Hits	129	Shared Neighborhood Hits	99
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

TRPV3_HUMAN
NC score	0.221658 (rank : 288)	θ value	θ > 10 (rank : 1309)
Query Neighborhood Hits	997	Target Neighborhood Hits	198	Shared Neighborhood Hits	143
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPV3_MOUSE
NC score	0.221150 (rank : 289)	θ value	θ > 10 (rank : 1310)
Query Neighborhood Hits	997	Target Neighborhood Hits	188	Shared Neighborhood Hits	132
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV1_HUMAN
NC score	0.214821 (rank : 290)	θ value	0.47712 (rank : 512)
Query Neighborhood Hits	997	Target Neighborhood Hits	184	Shared Neighborhood Hits	147
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

CMTA1_HUMAN
NC score	0.213256 (rank : 291)	θ value	0.0961366 (rank : 410)
Query Neighborhood Hits	997	Target Neighborhood Hits	217	Shared Neighborhood Hits	126
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

TRPV2_HUMAN
NC score	0.212091 (rank : 292)	θ value	0.0113563 (rank : 343)
Query Neighborhood Hits	997	Target Neighborhood Hits	130	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

BAT4_HUMAN
NC score	0.211960 (rank : 293)	θ value	θ > 10 (rank : 1033)
Query Neighborhood Hits	997	Target Neighborhood Hits	157	Shared Neighborhood Hits	113
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

WASIP_HUMAN
NC score	0.210151 (rank : 294)	θ value	7.1131e-05 (rank : 261)
Query Neighborhood Hits	997	Target Neighborhood Hits	458	Shared Neighborhood Hits	219
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

ANKR9_HUMAN
NC score	0.207516 (rank : 295)	θ value	θ > 10 (rank : 1015)
Query Neighborhood Hits	997	Target Neighborhood Hits	99	Shared Neighborhood Hits	97
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

PRP2_MOUSE
NC score	0.197662 (rank : 296)	θ value	0.0252991 (rank : 366)
Query Neighborhood Hits	997	Target Neighborhood Hits	347	Shared Neighborhood Hits	180
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRP1_HUMAN
NC score	0.196475 (rank : 297)	θ value	0.0563607 (rank : 395)
Query Neighborhood Hits	997	Target Neighborhood Hits	385	Shared Neighborhood Hits	193
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

CMTA2_HUMAN
NC score	0.191156 (rank : 298)	θ value	0.0330416 (rank : 369)
Query Neighborhood Hits	997	Target Neighborhood Hits	199	Shared Neighborhood Hits	130
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

WASIP_MOUSE
NC score	0.187084 (rank : 299)	θ value	1.81305 (rank : 651)
Query Neighborhood Hits	997	Target Neighborhood Hits	392	Shared Neighborhood Hits	211
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

PRB4S_HUMAN
NC score	0.182255 (rank : 300)	θ value	0.279714 (rank : 472)
Query Neighborhood Hits	997	Target Neighborhood Hits	330	Shared Neighborhood Hits	171
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

CMTA2_MOUSE
NC score	0.179591 (rank : 301)	θ value	0.0330416 (rank : 370)
Query Neighborhood Hits	997	Target Neighborhood Hits	216	Shared Neighborhood Hits	125
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

NACAM_MOUSE
NC score	0.174498 (rank : 302)	θ value	4.45536e-07 (rank : 211)
Query Neighborhood Hits	997	Target Neighborhood Hits	1866	Shared Neighborhood Hits	448
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PRB3_HUMAN
NC score	0.172956 (rank : 303)	θ value	0.62314 (rank : 529)
Query Neighborhood Hits	997	Target Neighborhood Hits	318	Shared Neighborhood Hits	161
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

TRPV2_MOUSE
NC score	0.167923 (rank : 304)	θ value	0.0431538 (rank : 389)
Query Neighborhood Hits	997	Target Neighborhood Hits	111	Shared Neighborhood Hits	95
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

MUC1_HUMAN
NC score	0.167638 (rank : 305)	θ value	4.58923e-20 (rank : 43)
Query Neighborhood Hits	997	Target Neighborhood Hits	975	Shared Neighborhood Hits	316
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

GSCR1_HUMAN
NC score	0.166816 (rank : 306)	θ value	0.47712 (rank : 499)
Query Neighborhood Hits	997	Target Neighborhood Hits	674	Shared Neighborhood Hits	279
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

OGFR_HUMAN
NC score	0.166160 (rank : 307)	θ value	2.61198e-07 (rank : 200)
Query Neighborhood Hits	997	Target Neighborhood Hits	1582	Shared Neighborhood Hits	420
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

SRRM1_MOUSE
NC score	0.163299 (rank : 308)	θ value	0.47712 (rank : 508)
Query Neighborhood Hits	997	Target Neighborhood Hits	966	Shared Neighborhood Hits	287
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

WIRE_MOUSE
NC score	0.162371 (rank : 309)	θ value	0.0193708 (rank : 359)
Query Neighborhood Hits	997	Target Neighborhood Hits	310	Shared Neighborhood Hits	170
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

PRR12_HUMAN
NC score	0.162146 (rank : 310)	θ value	θ > 10 (rank : 1214)
Query Neighborhood Hits	997	Target Neighborhood Hits	460	Shared Neighborhood Hits	211
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PRRT3_HUMAN
NC score	0.160447 (rank : 311)	θ value	1.43324e-05 (rank : 237)
Query Neighborhood Hits	997	Target Neighborhood Hits	998	Shared Neighborhood Hits	331
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

WIRE_HUMAN
NC score	0.159538 (rank : 312)	θ value	0.365318 (rank : 490)
Query Neighborhood Hits	997	Target Neighborhood Hits	329	Shared Neighborhood Hits	176
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

SRRM1_HUMAN
NC score	0.159416 (rank : 313)	θ value	0.279714 (rank : 475)
Query Neighborhood Hits	997	Target Neighborhood Hits	690	Shared Neighborhood Hits	224
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

PRG4_HUMAN
NC score	0.158422 (rank : 314)	θ value	0.0193708 (rank : 354)
Query Neighborhood Hits	997	Target Neighborhood Hits	764	Shared Neighborhood Hits	260
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

MDC1_HUMAN
NC score	0.154311 (rank : 315)	θ value	2.21117e-06 (rank : 223)
Query Neighborhood Hits	997	Target Neighborhood Hits	1446	Shared Neighborhood Hits	321
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MUC7_HUMAN
NC score	0.154117 (rank : 316)	θ value	θ > 10 (rank : 1187)
Query Neighborhood Hits	997	Target Neighborhood Hits	538	Shared Neighborhood Hits	208
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

TARSH_HUMAN
NC score	0.150745 (rank : 317)	θ value	0.00175202 (rank : 303)
Query Neighborhood Hits	997	Target Neighborhood Hits	768	Shared Neighborhood Hits	265
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

NCOA6_HUMAN
NC score	0.150209 (rank : 318)	θ value	9.29e-05 (rank : 265)
Query Neighborhood Hits	997	Target Neighborhood Hits	1202	Shared Neighborhood Hits	354
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

BAT2_HUMAN
NC score	0.148100 (rank : 319)	θ value	3.0926 (rank : 707)
Query Neighborhood Hits	997	Target Neighborhood Hits	931	Shared Neighborhood Hits	328
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

TAF4_HUMAN
NC score	0.147114 (rank : 320)	θ value	6.88961 (rank : 908)
Query Neighborhood Hits	997	Target Neighborhood Hits	687	Shared Neighborhood Hits	238
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

BSN_MOUSE
NC score	0.144885 (rank : 321)	θ value	0.0736092 (rank : 400)
Query Neighborhood Hits	997	Target Neighborhood Hits	2057	Shared Neighborhood Hits	472
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

WBP11_MOUSE
NC score	0.143504 (rank : 322)	θ value	0.163984 (rank : 446)
Query Neighborhood Hits	997	Target Neighborhood Hits	362	Shared Neighborhood Hits	165
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

SON_HUMAN
NC score	0.143439 (rank : 323)	θ value	5.44631e-05 (rank : 256)
Query Neighborhood Hits	997	Target Neighborhood Hits	1568	Shared Neighborhood Hits	411
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

WBP11_HUMAN
NC score	0.142919 (rank : 324)	θ value	0.279714 (rank : 476)
Query Neighborhood Hits	997	Target Neighborhood Hits	354	Shared Neighborhood Hits	164
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

NCOA6_MOUSE
NC score	0.140841 (rank : 325)	θ value	0.00869519 (rank : 336)
Query Neighborhood Hits	997	Target Neighborhood Hits	1076	Shared Neighborhood Hits	324
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

ATN1_HUMAN
NC score	0.140642 (rank : 326)	θ value	0.163984 (rank : 434)
Query Neighborhood Hits	997	Target Neighborhood Hits	676	Shared Neighborhood Hits	216
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

MDC1_MOUSE
NC score	0.140099 (rank : 327)	θ value	0.000121331 (rank : 268)
Query Neighborhood Hits	997	Target Neighborhood Hits	998	Shared Neighborhood Hits	275
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MBD6_HUMAN
NC score	0.138957 (rank : 328)	θ value	θ > 10 (rank : 1169)
Query Neighborhood Hits	997	Target Neighborhood Hits	349	Shared Neighborhood Hits	171
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

PRG4_MOUSE
NC score	0.136527 (rank : 329)	θ value	0.0736092 (rank : 404)
Query Neighborhood Hits	997	Target Neighborhood Hits	624	Shared Neighborhood Hits	201
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PCLO_HUMAN
NC score	0.136022 (rank : 330)	θ value	0.0148317 (rank : 350)
Query Neighborhood Hits	997	Target Neighborhood Hits	2046	Shared Neighborhood Hits	441
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SASH1_MOUSE
NC score	0.136008 (rank : 331)	θ value	0.00134147 (rank : 297)
Query Neighborhood Hits	997	Target Neighborhood Hits	263	Shared Neighborhood Hits	120
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

BSN_HUMAN
NC score	0.133774 (rank : 332)	θ value	0.279714 (rank : 464)
Query Neighborhood Hits	997	Target Neighborhood Hits	1537	Shared Neighborhood Hits	394
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

RGS3_MOUSE
NC score	0.132514 (rank : 333)	θ value	5.44631e-05 (rank : 255)
Query Neighborhood Hits	997	Target Neighborhood Hits	1621	Shared Neighborhood Hits	408
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

PCLO_MOUSE
NC score	0.131853 (rank : 334)	θ value	0.000121331 (rank : 269)
Query Neighborhood Hits	997	Target Neighborhood Hits	2275	Shared Neighborhood Hits	490
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SASH1_HUMAN
NC score	0.131138 (rank : 335)	θ value	0.0563607 (rank : 396)
Query Neighborhood Hits	997	Target Neighborhood Hits	292	Shared Neighborhood Hits	145
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

MLL3_HUMAN
NC score	0.130888 (rank : 336)	θ value	7.1131e-05 (rank : 260)
Query Neighborhood Hits	997	Target Neighborhood Hits	1644	Shared Neighborhood Hits	342
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

SRRM2_HUMAN
NC score	0.130571 (rank : 337)	θ value	8.99809 (rank : 982)
Query Neighborhood Hits	997	Target Neighborhood Hits	1296	Shared Neighborhood Hits	311
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

BCL9_HUMAN
NC score	0.130240 (rank : 338)	θ value	0.0330416 (rank : 368)
Query Neighborhood Hits	997	Target Neighborhood Hits	1008	Shared Neighborhood Hits	327
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

MLL2_HUMAN
NC score	0.129912 (rank : 339)	θ value	3.0926 (rank : 727)
Query Neighborhood Hits	997	Target Neighborhood Hits	1788	Shared Neighborhood Hits	433
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

RAPH1_HUMAN
NC score	0.129545 (rank : 340)	θ value	1.38821 (rank : 605)
Query Neighborhood Hits	997	Target Neighborhood Hits	593	Shared Neighborhood Hits	261
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

BAT2_MOUSE
NC score	0.129406 (rank : 341)	θ value	0.0961366 (rank : 408)
Query Neighborhood Hits	997	Target Neighborhood Hits	947	Shared Neighborhood Hits	337
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

YLPM1_MOUSE
NC score	0.129062 (rank : 342)	θ value	0.365318 (rank : 491)
Query Neighborhood Hits	997	Target Neighborhood Hits	505	Shared Neighborhood Hits	201
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

BCL9_MOUSE
NC score	0.128880 (rank : 343)	θ value	0.0563607 (rank : 392)
Query Neighborhood Hits	997	Target Neighborhood Hits	770	Shared Neighborhood Hits	287
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

LRRK1_MOUSE
NC score	0.126993 (rank : 344)	θ value	0.0252991 (rank : 362)
Query Neighborhood Hits	997	Target Neighborhood Hits	1267	Shared Neighborhood Hits	186
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

MLL3_MOUSE
NC score	0.126342 (rank : 345)	θ value	8.11959e-09 (rank : 166)
Query Neighborhood Hits	997	Target Neighborhood Hits	1399	Shared Neighborhood Hits	299
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

ANKF1_HUMAN
NC score	0.126197 (rank : 346)	θ value	θ > 10 (rank : 1014)
Query Neighborhood Hits	997	Target Neighborhood Hits	126	Shared Neighborhood Hits	78
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

GGN_MOUSE
NC score	0.124419 (rank : 347)	θ value	3.0926 (rank : 721)
Query Neighborhood Hits	997	Target Neighborhood Hits	311	Shared Neighborhood Hits	155
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

RERE_HUMAN
NC score	0.124082 (rank : 348)	θ value	2.36792 (rank : 691)
Query Neighborhood Hits	997	Target Neighborhood Hits	779	Shared Neighborhood Hits	269
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

ALEX_HUMAN
NC score	0.123987 (rank : 349)	θ value	0.279714 (rank : 463)
Query Neighborhood Hits	997	Target Neighborhood Hits	361	Shared Neighborhood Hits	159
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

SRRM2_MOUSE
NC score	0.123694 (rank : 350)	θ value	6.88961 (rank : 904)
Query Neighborhood Hits	997	Target Neighborhood Hits	1470	Shared Neighborhood Hits	329
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

MAGE1_HUMAN
NC score	0.123332 (rank : 351)	θ value	6.43352e-06 (rank : 230)
Query Neighborhood Hits	997	Target Neighborhood Hits	1389	Shared Neighborhood Hits	381
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

CJ078_MOUSE
NC score	0.122444 (rank : 352)	θ value	θ > 10 (rank : 1055)
Query Neighborhood Hits	997	Target Neighborhood Hits	559	Shared Neighborhood Hits	184
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

RERE_MOUSE
NC score	0.122415 (rank : 353)	θ value	2.36792 (rank : 692)
Query Neighborhood Hits	997	Target Neighborhood Hits	785	Shared Neighborhood Hits	260
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

WASL_MOUSE
NC score	0.120648 (rank : 354)	θ value	1.81305 (rank : 652)
Query Neighborhood Hits	997	Target Neighborhood Hits	339	Shared Neighborhood Hits	184
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

CPSF6_MOUSE
NC score	0.119611 (rank : 355)	θ value	1.38821 (rank : 591)
Query Neighborhood Hits	997	Target Neighborhood Hits	356	Shared Neighborhood Hits	160
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CN032_HUMAN
NC score	0.119609 (rank : 356)	θ value	θ > 10 (rank : 1056)
Query Neighborhood Hits	997	Target Neighborhood Hits	267	Shared Neighborhood Hits	137
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CPSF6_HUMAN
NC score	0.118438 (rank : 357)	θ value	1.38821 (rank : 590)
Query Neighborhood Hits	997	Target Neighborhood Hits	359	Shared Neighborhood Hits	160
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

SF3A2_MOUSE
NC score	0.118274 (rank : 358)	θ value	θ > 10 (rank : 1262)
Query Neighborhood Hits	997	Target Neighborhood Hits	247	Shared Neighborhood Hits	130
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

CK024_HUMAN
NC score	0.118198 (rank : 359)	θ value	0.0563607 (rank : 393)
Query Neighborhood Hits	997	Target Neighborhood Hits	408	Shared Neighborhood Hits	161
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

K1802_MOUSE
NC score	0.117405 (rank : 360)	θ value	4.45536e-07 (rank : 210)
Query Neighborhood Hits	997	Target Neighborhood Hits	1596	Shared Neighborhood Hits	333
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

WASL_HUMAN
NC score	0.116572 (rank : 361)	θ value	2.36792 (rank : 698)
Query Neighborhood Hits	997	Target Neighborhood Hits	312	Shared Neighborhood Hits	178
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

CN155_HUMAN
NC score	0.116482 (rank : 362)	θ value	θ > 10 (rank : 1058)
Query Neighborhood Hits	997	Target Neighborhood Hits	385	Shared Neighborhood Hits	144
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

TRPV4_HUMAN
NC score	0.115811 (rank : 363)	θ value	θ > 10 (rank : 1311)
Query Neighborhood Hits	997	Target Neighborhood Hits	150	Shared Neighborhood Hits	93
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

CN032_MOUSE
NC score	0.115726 (rank : 364)	θ value	θ > 10 (rank : 1057)
Query Neighborhood Hits	997	Target Neighborhood Hits	233	Shared Neighborhood Hits	134
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

EPHB6_HUMAN
NC score	0.115693 (rank : 365)	θ value	0.000602161 (rank : 284)
Query Neighborhood Hits	997	Target Neighborhood Hits	912	Shared Neighborhood Hits	111
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

EPHB6_MOUSE
NC score	0.114526 (rank : 366)	θ value	0.00509761 (rank : 323)
Query Neighborhood Hits	997	Target Neighborhood Hits	906	Shared Neighborhood Hits	105
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

EPHA5_HUMAN
NC score	0.113625 (rank : 367)	θ value	1.38499e-08 (rank : 169)
Query Neighborhood Hits	997	Target Neighborhood Hits	1009	Shared Neighborhood Hits	112
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

ENAH_MOUSE
NC score	0.112837 (rank : 368)	θ value	θ > 10 (rank : 1082)
Query Neighborhood Hits	997	Target Neighborhood Hits	919	Shared Neighborhood Hits	258
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

MLL4_HUMAN
NC score	0.112733 (rank : 369)	θ value	2.36792 (rank : 681)
Query Neighborhood Hits	997	Target Neighborhood Hits	722	Shared Neighborhood Hits	257
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

CIC_HUMAN
NC score	0.112685 (rank : 370)	θ value	0.0736092 (rank : 401)
Query Neighborhood Hits	997	Target Neighborhood Hits	992	Shared Neighborhood Hits	344
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SON_MOUSE
NC score	0.112552 (rank : 371)	θ value	2.36792 (rank : 695)
Query Neighborhood Hits	997	Target Neighborhood Hits	957	Shared Neighborhood Hits	283
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SYN1_HUMAN
NC score	0.112387 (rank : 372)	θ value	1.81305 (rank : 643)
Query Neighborhood Hits	997	Target Neighborhood Hits	419	Shared Neighborhood Hits	207
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

EPHA6_HUMAN
NC score	0.112030 (rank : 373)	θ value	0.000270298 (rank : 275)
Query Neighborhood Hits	997	Target Neighborhood Hits	959	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

BASP_MOUSE
NC score	0.111695 (rank : 374)	θ value	θ > 10 (rank : 1031)
Query Neighborhood Hits	997	Target Neighborhood Hits	260	Shared Neighborhood Hits	91
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

YLPM1_HUMAN
NC score	0.111532 (rank : 375)	θ value	6.88961 (rank : 917)
Query Neighborhood Hits	997	Target Neighborhood Hits	670	Shared Neighborhood Hits	218
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

SHAN2_MOUSE
NC score	0.111506 (rank : 376)	θ value	0.0563607 (rank : 398)
Query Neighborhood Hits	997	Target Neighborhood Hits	446	Shared Neighborhood Hits	148
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

EPHA7_HUMAN
NC score	0.111422 (rank : 377)	θ value	4.45536e-07 (rank : 209)
Query Neighborhood Hits	997	Target Neighborhood Hits	1053	Shared Neighborhood Hits	112
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

FA47A_HUMAN
NC score	0.110992 (rank : 378)	θ value	9.29e-05 (rank : 262)
Query Neighborhood Hits	997	Target Neighborhood Hits	451	Shared Neighborhood Hits	148
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

GGN_HUMAN
NC score	0.110939 (rank : 379)	θ value	θ > 10 (rank : 1106)
Query Neighborhood Hits	997	Target Neighborhood Hits	269	Shared Neighborhood Hits	142
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

EPHA6_MOUSE
NC score	0.110657 (rank : 380)	θ value	0.00134147 (rank : 293)
Query Neighborhood Hits	997	Target Neighborhood Hits	946	Shared Neighborhood Hits	94
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHB4_HUMAN
NC score	0.110537 (rank : 381)	θ value	2.21117e-06 (rank : 222)
Query Neighborhood Hits	997	Target Neighborhood Hits	1056	Shared Neighborhood Hits	117
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

SF3A2_HUMAN
NC score	0.110470 (rank : 382)	θ value	θ > 10 (rank : 1261)
Query Neighborhood Hits	997	Target Neighborhood Hits	263	Shared Neighborhood Hits	129
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

EPHB3_HUMAN
NC score	0.110439 (rank : 383)	θ value	8.40245e-06 (rank : 233)
Query Neighborhood Hits	997	Target Neighborhood Hits	996	Shared Neighborhood Hits	111
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

LCP2_HUMAN
NC score	0.110396 (rank : 384)	θ value	0.000121331 (rank : 267)
Query Neighborhood Hits	997	Target Neighborhood Hits	531	Shared Neighborhood Hits	183
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

EPHAA_HUMAN
NC score	0.110389 (rank : 385)	θ value	0.00102713 (rank : 289)
Query Neighborhood Hits	997	Target Neighborhood Hits	960	Shared Neighborhood Hits	103
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

EPHA1_MOUSE
NC score	0.110384 (rank : 386)	θ value	3.41135e-07 (rank : 204)
Query Neighborhood Hits	997	Target Neighborhood Hits	958	Shared Neighborhood Hits	105
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

EPHA1_HUMAN
NC score	0.110313 (rank : 387)	θ value	4.45536e-07 (rank : 208)
Query Neighborhood Hits	997	Target Neighborhood Hits	997	Shared Neighborhood Hits	113
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

EPHA7_MOUSE
NC score	0.110313 (rank : 388)	θ value	9.92553e-07 (rank : 217)
Query Neighborhood Hits	997	Target Neighborhood Hits	1025	Shared Neighborhood Hits	104
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

SET1A_HUMAN
NC score	0.110194 (rank : 389)	θ value	θ > 10 (rank : 1256)
Query Neighborhood Hits	997	Target Neighborhood Hits	690	Shared Neighborhood Hits	210
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

EPHB2_HUMAN
NC score	0.109854 (rank : 390)	θ value	2.61198e-07 (rank : 199)
Query Neighborhood Hits	997	Target Neighborhood Hits	983	Shared Neighborhood Hits	106
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

WASP_MOUSE
NC score	0.109762 (rank : 391)	θ value	0.0148317 (rank : 351)
Query Neighborhood Hits	997	Target Neighborhood Hits	223	Shared Neighborhood Hits	127
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

PI5PA_HUMAN
NC score	0.109504 (rank : 392)	θ value	0.0252991 (rank : 365)
Query Neighborhood Hits	997	Target Neighborhood Hits	749	Shared Neighborhood Hits	289
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

EPHA2_HUMAN
NC score	0.109476 (rank : 393)	θ value	8.97725e-08 (rank : 184)
Query Neighborhood Hits	997	Target Neighborhood Hits	1021	Shared Neighborhood Hits	108
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

EPHA2_MOUSE
NC score	0.109464 (rank : 394)	θ value	2.61198e-07 (rank : 198)
Query Neighborhood Hits	997	Target Neighborhood Hits	1020	Shared Neighborhood Hits	108
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

EPHB3_MOUSE
NC score	0.109317 (rank : 395)	θ value	3.19293e-05 (rank : 245)
Query Neighborhood Hits	997	Target Neighborhood Hits	996	Shared Neighborhood Hits	108
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

EPHB4_MOUSE
NC score	0.109067 (rank : 396)	θ value	2.88788e-06 (rank : 227)
Query Neighborhood Hits	997	Target Neighborhood Hits	1013	Shared Neighborhood Hits	112
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

EPHA8_MOUSE
NC score	0.108696 (rank : 397)	θ value	0.000158464 (rank : 270)
Query Neighborhood Hits	997	Target Neighborhood Hits	969	Shared Neighborhood Hits	101
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

EPHB2_MOUSE
NC score	0.108207 (rank : 398)	θ value	1.09739e-05 (rank : 236)
Query Neighborhood Hits	997	Target Neighborhood Hits	982	Shared Neighborhood Hits	106
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

NFH_MOUSE
NC score	0.108204 (rank : 399)	θ value	5.62301e-10 (rank : 152)
Query Neighborhood Hits	997	Target Neighborhood Hits	2247	Shared Neighborhood Hits	420
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RTP3_MOUSE
NC score	0.107216 (rank : 400)	θ value	9.29e-05 (rank : 266)
Query Neighborhood Hits	997	Target Neighborhood Hits	374	Shared Neighborhood Hits	137
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

EPHB1_HUMAN
NC score	0.107019 (rank : 401)	θ value	1.09739e-05 (rank : 235)
Query Neighborhood Hits	997	Target Neighborhood Hits	988	Shared Neighborhood Hits	106
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

SHAN2_HUMAN
NC score	0.106781 (rank : 402)	θ value	0.0563607 (rank : 397)
Query Neighborhood Hits	997	Target Neighborhood Hits	346	Shared Neighborhood Hits	119
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

PRR13_HUMAN
NC score	0.106696 (rank : 403)	θ value	θ > 10 (rank : 1215)
Query Neighborhood Hits	997	Target Neighborhood Hits	105	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

EPHA8_HUMAN
NC score	0.106642 (rank : 404)	θ value	0.00035302 (rank : 281)
Query Neighborhood Hits	997	Target Neighborhood Hits	956	Shared Neighborhood Hits	100
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

SFPQ_MOUSE
NC score	0.106432 (rank : 405)	θ value	0.279714 (rank : 474)
Query Neighborhood Hits	997	Target Neighborhood Hits	958	Shared Neighborhood Hits	246
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

TRPV4_MOUSE
NC score	0.106127 (rank : 406)	θ value	θ > 10 (rank : 1312)
Query Neighborhood Hits	997	Target Neighborhood Hits	117	Shared Neighborhood Hits	77
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

EPHA4_MOUSE
NC score	0.105400 (rank : 407)	θ value	0.00020696 (rank : 273)
Query Neighborhood Hits	997	Target Neighborhood Hits	982	Shared Neighborhood Hits	100
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

LRRK1_HUMAN
NC score	0.105136 (rank : 408)	θ value	0.00298849 (rank : 312)
Query Neighborhood Hits	997	Target Neighborhood Hits	1237	Shared Neighborhood Hits	163
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

EPHA4_HUMAN
NC score	0.105129 (rank : 409)	θ value	0.00035302 (rank : 280)
Query Neighborhood Hits	997	Target Neighborhood Hits	975	Shared Neighborhood Hits	100
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

FA47B_HUMAN
NC score	0.104673 (rank : 410)	θ value	0.00869519 (rank : 333)
Query Neighborhood Hits	997	Target Neighborhood Hits	431	Shared Neighborhood Hits	154
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

SYN1_MOUSE
NC score	0.104288 (rank : 411)	θ value	1.06291 (rank : 580)
Query Neighborhood Hits	997	Target Neighborhood Hits	363	Shared Neighborhood Hits	180
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

CS016_HUMAN
NC score	0.104164 (rank : 412)	θ value	θ > 10 (rank : 1066)
Query Neighborhood Hits	997	Target Neighborhood Hits	310	Shared Neighborhood Hits	145
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

EPHA5_MOUSE
NC score	0.103232 (rank : 413)	θ value	5.81887e-07 (rank : 212)
Query Neighborhood Hits	997	Target Neighborhood Hits	950	Shared Neighborhood Hits	101
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

MUCDL_HUMAN
NC score	0.103019 (rank : 414)	θ value	0.0113563 (rank : 339)
Query Neighborhood Hits	997	Target Neighborhood Hits	777	Shared Neighborhood Hits	239
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

CEND3_HUMAN
NC score	0.102880 (rank : 415)	θ value	0.00665767 (rank : 326)
Query Neighborhood Hits	997	Target Neighborhood Hits	275	Shared Neighborhood Hits	122
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

TRPC6_HUMAN
NC score	0.102649 (rank : 416)	θ value	8.99809 (rank : 992)
Query Neighborhood Hits	997	Target Neighborhood Hits	171	Shared Neighborhood Hits	102
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

PRP5_HUMAN
NC score	0.102234 (rank : 417)	θ value	θ > 10 (rank : 1211)
Query Neighborhood Hits	997	Target Neighborhood Hits	108	Shared Neighborhood Hits	63
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

K1543_MOUSE
NC score	0.101185 (rank : 418)	θ value	0.365318 (rank : 483)
Query Neighborhood Hits	997	Target Neighborhood Hits	497	Shared Neighborhood Hits	163
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

RGS3_HUMAN
NC score	0.100786 (rank : 419)	θ value	1.99992e-07 (rank : 194)
Query Neighborhood Hits	997	Target Neighborhood Hits	1375	Shared Neighborhood Hits	335
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SARM1_MOUSE
NC score	0.100577 (rank : 420)	θ value	0.00102713 (rank : 292)
Query Neighborhood Hits	997	Target Neighborhood Hits	54	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PDS3, Q5SYG5, Q5SYG6, Q6A054, Q6SZW0, Q8BRI9	Gene names	Sarm1, Kiaa0524
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Tir-1 homolog).

MUC2_HUMAN
NC score	0.100228 (rank : 421)	θ value	θ > 10 (rank : 1185)
Query Neighborhood Hits	997	Target Neighborhood Hits	906	Shared Neighborhood Hits	237
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PRR8_HUMAN
NC score	0.099966 (rank : 422)	θ value	0.0330416 (rank : 377)
Query Neighborhood Hits	997	Target Neighborhood Hits	217	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

OGFR_MOUSE
NC score	0.099327 (rank : 423)	θ value	0.0113563 (rank : 340)
Query Neighborhood Hits	997	Target Neighborhood Hits	584	Shared Neighborhood Hits	171
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

SFPQ_HUMAN
NC score	0.099228 (rank : 424)	θ value	4.03905 (rank : 794)
Query Neighborhood Hits	997	Target Neighborhood Hits	986	Shared Neighborhood Hits	273
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

WASF2_MOUSE
NC score	0.099118 (rank : 425)	θ value	θ > 10 (rank : 1325)
Query Neighborhood Hits	997	Target Neighborhood Hits	315	Shared Neighborhood Hits	182
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

CBP_MOUSE
NC score	0.099048 (rank : 426)	θ value	3.0926 (rank : 710)
Query Neighborhood Hits	997	Target Neighborhood Hits	1051	Shared Neighborhood Hits	301
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CEND3_MOUSE
NC score	0.098225 (rank : 427)	θ value	0.0431538 (rank : 379)
Query Neighborhood Hits	997	Target Neighborhood Hits	228	Shared Neighborhood Hits	103
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

MISS_MOUSE
NC score	0.097699 (rank : 428)	θ value	1.06291 (rank : 569)
Query Neighborhood Hits	997	Target Neighborhood Hits	444	Shared Neighborhood Hits	188
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

CBP_HUMAN
NC score	0.097672 (rank : 429)	θ value	θ > 10 (rank : 1046)
Query Neighborhood Hits	997	Target Neighborhood Hits	941	Shared Neighborhood Hits	293
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

TXND2_HUMAN
NC score	0.097291 (rank : 430)	θ value	0.0563607 (rank : 399)
Query Neighborhood Hits	997	Target Neighborhood Hits	793	Shared Neighborhood Hits	165
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

BCAR1_HUMAN
NC score	0.097176 (rank : 431)	θ value	0.0563607 (rank : 391)
Query Neighborhood Hits	997	Target Neighborhood Hits	554	Shared Neighborhood Hits	201
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

FYB_HUMAN
NC score	0.097025 (rank : 432)	θ value	0.0330416 (rank : 373)
Query Neighborhood Hits	997	Target Neighborhood Hits	379	Shared Neighborhood Hits	139
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

CDN1C_HUMAN
NC score	0.096777 (rank : 433)	θ value	0.813845 (rank : 535)
Query Neighborhood Hits	997	Target Neighborhood Hits	168	Shared Neighborhood Hits	95
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CS007_MOUSE
NC score	0.096766 (rank : 434)	θ value	0.125558 (rank : 420)
Query Neighborhood Hits	997	Target Neighborhood Hits	464	Shared Neighborhood Hits	168
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

BASP_HUMAN
NC score	0.096670 (rank : 435)	θ value	θ > 10 (rank : 1030)
Query Neighborhood Hits	997	Target Neighborhood Hits	321	Shared Neighborhood Hits	110
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

EPHA3_HUMAN
NC score	0.096465 (rank : 436)	θ value	0.0330416 (rank : 372)
Query Neighborhood Hits	997	Target Neighborhood Hits	1005	Shared Neighborhood Hits	93
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

PRR13_MOUSE
NC score	0.096454 (rank : 437)	θ value	θ > 10 (rank : 1216)
Query Neighborhood Hits	997	Target Neighborhood Hits	54	Shared Neighborhood Hits	37
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

ARI1A_HUMAN
NC score	0.096428 (rank : 438)	θ value	8.99809 (rank : 927)
Query Neighborhood Hits	997	Target Neighborhood Hits	787	Shared Neighborhood Hits	251
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

FMNL_HUMAN
NC score	0.096423 (rank : 439)	θ value	0.813845 (rank : 542)
Query Neighborhood Hits	997	Target Neighborhood Hits	529	Shared Neighborhood Hits	182
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

EPHA3_MOUSE
NC score	0.096287 (rank : 440)	θ value	0.0736092 (rank : 402)
Query Neighborhood Hits	997	Target Neighborhood Hits	1009	Shared Neighborhood Hits	92
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

EP300_HUMAN
NC score	0.095668 (rank : 441)	θ value	θ > 10 (rank : 1084)
Query Neighborhood Hits	997	Target Neighborhood Hits	821	Shared Neighborhood Hits	296
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

BAG3_MOUSE
NC score	0.095514 (rank : 442)	θ value	0.365318 (rank : 478)
Query Neighborhood Hits	997	Target Neighborhood Hits	513	Shared Neighborhood Hits	209
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

PELP1_MOUSE
NC score	0.094740 (rank : 443)	θ value	2.36792 (rank : 686)
Query Neighborhood Hits	997	Target Neighborhood Hits	709	Shared Neighborhood Hits	236
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

SMR3A_HUMAN
NC score	0.094012 (rank : 444)	θ value	θ > 10 (rank : 1270)
Query Neighborhood Hits	997	Target Neighborhood Hits	93	Shared Neighborhood Hits	53
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

CEL_HUMAN
NC score	0.093928 (rank : 445)	θ value	1.87187e-05 (rank : 239)
Query Neighborhood Hits	997	Target Neighborhood Hits	896	Shared Neighborhood Hits	296
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

FMN2_HUMAN
NC score	0.093831 (rank : 446)	θ value	1.81305 (rank : 618)
Query Neighborhood Hits	997	Target Neighborhood Hits	484	Shared Neighborhood Hits	180
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

TCOF_MOUSE
NC score	0.093563 (rank : 447)	θ value	θ > 10 (rank : 1284)
Query Neighborhood Hits	997	Target Neighborhood Hits	471	Shared Neighborhood Hits	143
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

GRIN1_HUMAN
NC score	0.093543 (rank : 448)	θ value	θ > 10 (rank : 1107)
Query Neighborhood Hits	997	Target Neighborhood Hits	681	Shared Neighborhood Hits	222
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

CIC_MOUSE
NC score	0.093418 (rank : 449)	θ value	0.21417 (rank : 451)
Query Neighborhood Hits	997	Target Neighborhood Hits	742	Shared Neighborhood Hits	266
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CU081_HUMAN
NC score	0.092984 (rank : 450)	θ value	θ > 10 (rank : 1071)
Query Neighborhood Hits	997	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

K1802_HUMAN
NC score	0.092569 (rank : 451)	θ value	0.00665767 (rank : 329)
Query Neighborhood Hits	997	Target Neighborhood Hits	1378	Shared Neighborhood Hits	310
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

ZN207_HUMAN
NC score	0.092331 (rank : 452)	θ value	θ > 10 (rank : 1339)
Query Neighborhood Hits	997	Target Neighborhood Hits	326	Shared Neighborhood Hits	107
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

MARCS_HUMAN
NC score	0.092084 (rank : 453)	θ value	1.81305 (rank : 627)
Query Neighborhood Hits	997	Target Neighborhood Hits	204	Shared Neighborhood Hits	79
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

WASF1_MOUSE
NC score	0.092044 (rank : 454)	θ value	1.81305 (rank : 650)
Query Neighborhood Hits	997	Target Neighborhood Hits	261	Shared Neighborhood Hits	145
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

DGKK_HUMAN
NC score	0.091953 (rank : 455)	θ value	θ > 10 (rank : 1076)
Query Neighborhood Hits	997	Target Neighborhood Hits	378	Shared Neighborhood Hits	149
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

TCGAP_HUMAN
NC score	0.091127 (rank : 456)	θ value	0.00390308 (rank : 320)
Query Neighborhood Hits	997	Target Neighborhood Hits	872	Shared Neighborhood Hits	288
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

BAT3_MOUSE
NC score	0.091118 (rank : 457)	θ value	θ > 10 (rank : 1032)
Query Neighborhood Hits	997	Target Neighborhood Hits	518	Shared Neighborhood Hits	219
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

NU214_HUMAN
NC score	0.090552 (rank : 458)	θ value	θ > 10 (rank : 1198)
Query Neighborhood Hits	997	Target Neighborhood Hits	657	Shared Neighborhood Hits	165
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

CABIN_HUMAN
NC score	0.090376 (rank : 459)	θ value	1.38821 (rank : 586)
Query Neighborhood Hits	997	Target Neighborhood Hits	490	Shared Neighborhood Hits	184
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

PRPE_HUMAN
NC score	0.090347 (rank : 460)	θ value	θ > 10 (rank : 1213)
Query Neighborhood Hits	997	Target Neighborhood Hits	44	Shared Neighborhood Hits	24
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

BCAR1_MOUSE
NC score	0.090141 (rank : 461)	θ value	0.0961366 (rank : 409)
Query Neighborhood Hits	997	Target Neighborhood Hits	438	Shared Neighborhood Hits	167
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

TAU_HUMAN
NC score	0.089884 (rank : 462)	θ value	4.03905 (rank : 799)
Query Neighborhood Hits	997	Target Neighborhood Hits	448	Shared Neighborhood Hits	203
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

WASF1_HUMAN
NC score	0.089840 (rank : 463)	θ value	1.81305 (rank : 649)
Query Neighborhood Hits	997	Target Neighborhood Hits	260	Shared Neighborhood Hits	148
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

MUC1_MOUSE
NC score	0.089831 (rank : 464)	θ value	θ > 10 (rank : 1184)
Query Neighborhood Hits	997	Target Neighborhood Hits	388	Shared Neighborhood Hits	93
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

DIDO1_HUMAN
NC score	0.089803 (rank : 465)	θ value	1.06291 (rank : 558)
Query Neighborhood Hits	997	Target Neighborhood Hits	960	Shared Neighborhood Hits	261
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

WASP_HUMAN
NC score	0.089555 (rank : 466)	θ value	6.88961 (rank : 916)
Query Neighborhood Hits	997	Target Neighborhood Hits	195	Shared Neighborhood Hits	110
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

CCNK_MOUSE
NC score	0.089473 (rank : 467)	θ value	θ > 10 (rank : 1047)
Query Neighborhood Hits	997	Target Neighborhood Hits	350	Shared Neighborhood Hits	163
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

MARCS_MOUSE
NC score	0.088940 (rank : 468)	θ value	θ > 10 (rank : 1165)
Query Neighborhood Hits	997	Target Neighborhood Hits	227	Shared Neighborhood Hits	93
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

NCOR2_HUMAN
NC score	0.088757 (rank : 469)	θ value	0.279714 (rank : 470)
Query Neighborhood Hits	997	Target Neighborhood Hits	870	Shared Neighborhood Hits	227
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

PCQAP_HUMAN
NC score	0.088491 (rank : 470)	θ value	θ > 10 (rank : 1200)
Query Neighborhood Hits	997	Target Neighborhood Hits	549	Shared Neighborhood Hits	158
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

DGKD_HUMAN
NC score	0.088331 (rank : 471)	θ value	0.0252991 (rank : 361)
Query Neighborhood Hits	997	Target Neighborhood Hits	231	Shared Neighborhood Hits	72
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

NOLC1_HUMAN
NC score	0.088017 (rank : 472)	θ value	θ > 10 (rank : 1192)
Query Neighborhood Hits	997	Target Neighborhood Hits	452	Shared Neighborhood Hits	110
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

SLY_MOUSE
NC score	0.087936 (rank : 473)	θ value	0.0736092 (rank : 406)
Query Neighborhood Hits	997	Target Neighborhood Hits	108	Shared Neighborhood Hits	42
SwissProt Accessions	Q8K352, Q3TBX0, Q9DBV2	Gene names	Sly
Domain Architecture
Description	SH3 protein expressed in lymphocytes.

TARA_HUMAN
NC score	0.087927 (rank : 474)	θ value	1.81305 (rank : 644)
Query Neighborhood Hits	997	Target Neighborhood Hits	1626	Shared Neighborhood Hits	306
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

PRPC_HUMAN
NC score	0.087517 (rank : 475)	θ value	θ > 10 (rank : 1212)
Query Neighborhood Hits	997	Target Neighborhood Hits	165	Shared Neighborhood Hits	67
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

MILK1_MOUSE
NC score	0.087502 (rank : 476)	θ value	0.0330416 (rank : 376)
Query Neighborhood Hits	997	Target Neighborhood Hits	788	Shared Neighborhood Hits	264
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

SAMN1_HUMAN
NC score	0.087491 (rank : 477)	θ value	0.125558 (rank : 427)
Query Neighborhood Hits	997	Target Neighborhood Hits	74	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NSI8, Q8NFF7, Q9C041	Gene names	SAMSN1, HACS1
Domain Architecture
Description	SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1) (SH3-SAM adaptor protein) (Hematopoietic adaptor containing SH3 and SAM domains 1).

SAMN1_MOUSE
NC score	0.087430 (rank : 478)	θ value	0.0961366 (rank : 414)
Query Neighborhood Hits	997	Target Neighborhood Hits	69	Shared Neighborhood Hits	37
SwissProt Accessions	P57725, Q8C6S2	Gene names	Samsn1
Domain Architecture
Description	SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1).

SARM1_HUMAN
NC score	0.087097 (rank : 479)	θ value	0.0113563 (rank : 341)
Query Neighborhood Hits	997	Target Neighborhood Hits	58	Shared Neighborhood Hits	19
SwissProt Accessions	Q6SZW1, O60277, Q7LGG3, Q9NXY5	Gene names	SARM1, KIAA0524, SARM
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Sterile alpha and Armadillo repeat protein) (Tir-1 homolog).

CTDP1_HUMAN
NC score	0.086712 (rank : 480)	θ value	0.0148317 (rank : 348)
Query Neighborhood Hits	997	Target Neighborhood Hits	416	Shared Neighborhood Hits	165
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

TRPC3_HUMAN
NC score	0.086300 (rank : 481)	θ value	6.88961 (rank : 911)
Query Neighborhood Hits	997	Target Neighborhood Hits	137	Shared Neighborhood Hits	81
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

TAU_MOUSE
NC score	0.086137 (rank : 482)	θ value	8.99809 (rank : 986)
Query Neighborhood Hits	997	Target Neighborhood Hits	502	Shared Neighborhood Hits	185
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

BAT3_HUMAN
NC score	0.085635 (rank : 483)	θ value	2.36792 (rank : 660)
Query Neighborhood Hits	997	Target Neighborhood Hits	490	Shared Neighborhood Hits	211
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

SLY_HUMAN
NC score	0.085207 (rank : 484)	θ value	0.0736092 (rank : 405)
Query Neighborhood Hits	997	Target Neighborhood Hits	81	Shared Neighborhood Hits	39
SwissProt Accessions	O75995	Gene names	SLY, CXorf9
Domain Architecture
Description	SH3 protein expressed in lymphocytes homolog.

SAPS1_HUMAN
NC score	0.084673 (rank : 485)	θ value	0.0193708 (rank : 356)
Query Neighborhood Hits	997	Target Neighborhood Hits	704	Shared Neighborhood Hits	255
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

K0310_HUMAN
NC score	0.084432 (rank : 486)	θ value	0.163984 (rank : 438)
Query Neighborhood Hits	997	Target Neighborhood Hits	420	Shared Neighborhood Hits	165
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

SFR15_HUMAN
NC score	0.084144 (rank : 487)	θ value	2.36792 (rank : 693)
Query Neighborhood Hits	997	Target Neighborhood Hits	368	Shared Neighborhood Hits	135
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

ZN385_HUMAN
NC score	0.084101 (rank : 488)	θ value	0.813845 (rank : 551)
Query Neighborhood Hits	997	Target Neighborhood Hits	614	Shared Neighborhood Hits	206
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

SYNJ1_HUMAN
NC score	0.084061 (rank : 489)	θ value	3.0926 (rank : 743)
Query Neighborhood Hits	997	Target Neighborhood Hits	498	Shared Neighborhood Hits	206
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

ATX2L_HUMAN
NC score	0.083963 (rank : 490)	θ value	0.163984 (rank : 435)
Query Neighborhood Hits	997	Target Neighborhood Hits	443	Shared Neighborhood Hits	168
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

TGON2_HUMAN
NC score	0.083877 (rank : 491)	θ value	θ > 10 (rank : 1294)
Query Neighborhood Hits	997	Target Neighborhood Hits	1037	Shared Neighborhood Hits	210
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

PELP1_HUMAN
NC score	0.083560 (rank : 492)	θ value	θ > 10 (rank : 1204)
Query Neighborhood Hits	997	Target Neighborhood Hits	596	Shared Neighborhood Hits	163
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

S23IP_MOUSE
NC score	0.083403 (rank : 493)	θ value	θ > 10 (rank : 1251)
Query Neighborhood Hits	997	Target Neighborhood Hits	363	Shared Neighborhood Hits	139
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

WASF2_HUMAN
NC score	0.083374 (rank : 494)	θ value	θ > 10 (rank : 1324)
Query Neighborhood Hits	997	Target Neighborhood Hits	280	Shared Neighborhood Hits	161
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

SNPC4_HUMAN
NC score	0.083371 (rank : 495)	θ value	4.03905 (rank : 797)
Query Neighborhood Hits	997	Target Neighborhood Hits	589	Shared Neighborhood Hits	220
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

MUC13_MOUSE
NC score	0.083333 (rank : 496)	θ value	θ > 10 (rank : 1183)
Query Neighborhood Hits	997	Target Neighborhood Hits	447	Shared Neighborhood Hits	111
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

LAD1_MOUSE
NC score	0.082972 (rank : 497)	θ value	θ > 10 (rank : 1144)
Query Neighborhood Hits	997	Target Neighborhood Hits	391	Shared Neighborhood Hits	110
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

K1543_HUMAN
NC score	0.082578 (rank : 498)	θ value	0.163984 (rank : 439)
Query Neighborhood Hits	997	Target Neighborhood Hits	435	Shared Neighborhood Hits	150
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

BRD4_MOUSE
NC score	0.081933 (rank : 499)	θ value	θ > 10 (rank : 1043)
Query Neighborhood Hits	997	Target Neighborhood Hits	845	Shared Neighborhood Hits	226
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

SC24C_HUMAN
NC score	0.081834 (rank : 500)	θ value	θ > 10 (rank : 1254)
Query Neighborhood Hits	997	Target Neighborhood Hits	662	Shared Neighborhood Hits	235
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

MINT_MOUSE
NC score	0.081823 (rank : 501)	θ value	0.21417 (rank : 457)
Query Neighborhood Hits	997	Target Neighborhood Hits	1514	Shared Neighborhood Hits	330
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

WASF4_HUMAN
NC score	0.081563 (rank : 502)	θ value	θ > 10 (rank : 1327)
Query Neighborhood Hits	997	Target Neighborhood Hits	282	Shared Neighborhood Hits	157
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

CRTC1_HUMAN
NC score	0.081350 (rank : 503)	θ value	6.88961 (rank : 876)
Query Neighborhood Hits	997	Target Neighborhood Hits	319	Shared Neighborhood Hits	158
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

MAP4_HUMAN
NC score	0.080804 (rank : 504)	θ value	0.125558 (rank : 423)
Query Neighborhood Hits	997	Target Neighborhood Hits	428	Shared Neighborhood Hits	140
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

HRX_HUMAN
NC score	0.079764 (rank : 505)	θ value	8.99809 (rank : 955)
Query Neighborhood Hits	997	Target Neighborhood Hits	825	Shared Neighborhood Hits	183
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

SGIP1_MOUSE
NC score	0.079609 (rank : 506)	θ value	3.0926 (rank : 739)
Query Neighborhood Hits	997	Target Neighborhood Hits	180	Shared Neighborhood Hits	96
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

K1683_HUMAN
NC score	0.079487 (rank : 507)	θ value	0.0961366 (rank : 412)
Query Neighborhood Hits	997	Target Neighborhood Hits	240	Shared Neighborhood Hits	88
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

TROAP_HUMAN
NC score	0.079330 (rank : 508)	θ value	0.47712 (rank : 511)
Query Neighborhood Hits	997	Target Neighborhood Hits	258	Shared Neighborhood Hits	102
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

PO121_HUMAN
NC score	0.079283 (rank : 509)	θ value	θ > 10 (rank : 1208)
Query Neighborhood Hits	997	Target Neighborhood Hits	344	Shared Neighborhood Hits	127
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

MADCA_HUMAN
NC score	0.078885 (rank : 510)	θ value	θ > 10 (rank : 1161)
Query Neighborhood Hits	997	Target Neighborhood Hits	221	Shared Neighborhood Hits	104
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

SSBP4_HUMAN
NC score	0.078877 (rank : 511)	θ value	0.125558 (rank : 429)
Query Neighborhood Hits	997	Target Neighborhood Hits	753	Shared Neighborhood Hits	262
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

SPR1B_MOUSE
NC score	0.078765 (rank : 512)	θ value	0.00665767 (rank : 330)
Query Neighborhood Hits	997	Target Neighborhood Hits	395	Shared Neighborhood Hits	146
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

T22D2_HUMAN
NC score	0.078485 (rank : 513)	θ value	θ > 10 (rank : 1281)
Query Neighborhood Hits	997	Target Neighborhood Hits	250	Shared Neighborhood Hits	107
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

TCOF_HUMAN
NC score	0.078401 (rank : 514)	θ value	θ > 10 (rank : 1283)
Query Neighborhood Hits	997	Target Neighborhood Hits	543	Shared Neighborhood Hits	140
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

PI5PA_MOUSE
NC score	0.078288 (rank : 515)	θ value	θ > 10 (rank : 1207)
Query Neighborhood Hits	997	Target Neighborhood Hits	331	Shared Neighborhood Hits	155
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

GRIN1_MOUSE
NC score	0.077799 (rank : 516)	θ value	8.99809 (rank : 951)
Query Neighborhood Hits	997	Target Neighborhood Hits	337	Shared Neighborhood Hits	126
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

TB182_HUMAN
NC score	0.077295 (rank : 517)	θ value	3.0926 (rank : 745)
Query Neighborhood Hits	997	Target Neighborhood Hits	414	Shared Neighborhood Hits	145
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

MBB1A_HUMAN
NC score	0.077258 (rank : 518)	θ value	0.21417 (rank : 456)
Query Neighborhood Hits	997	Target Neighborhood Hits	665	Shared Neighborhood Hits	196
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

SELV_HUMAN
NC score	0.077206 (rank : 519)	θ value	θ > 10 (rank : 1255)
Query Neighborhood Hits	997	Target Neighborhood Hits	118	Shared Neighborhood Hits	68
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

CEND1_HUMAN
NC score	0.077086 (rank : 520)	θ value	θ > 10 (rank : 1051)
Query Neighborhood Hits	997	Target Neighborhood Hits	284	Shared Neighborhood Hits	79
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

NCOR2_MOUSE
NC score	0.077068 (rank : 521)	θ value	0.0252991 (rank : 364)
Query Neighborhood Hits	997	Target Neighborhood Hits	790	Shared Neighborhood Hits	184
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

CO039_MOUSE
NC score	0.077031 (rank : 522)	θ value	6.88961 (rank : 870)
Query Neighborhood Hits	997	Target Neighborhood Hits	445	Shared Neighborhood Hits	176
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

TM108_MOUSE
NC score	0.076955 (rank : 523)	θ value	5.27518 (rank : 850)
Query Neighborhood Hits	997	Target Neighborhood Hits	336	Shared Neighborhood Hits	122
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

RP1L1_HUMAN
NC score	0.076816 (rank : 524)	θ value	θ > 10 (rank : 1245)
Query Neighborhood Hits	997	Target Neighborhood Hits	1072	Shared Neighborhood Hits	246
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

WNK2_HUMAN
NC score	0.076557 (rank : 525)	θ value	0.47712 (rank : 513)
Query Neighborhood Hits	997	Target Neighborhood Hits	1407	Shared Neighborhood Hits	309
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

DOT1L_HUMAN
NC score	0.076414 (rank : 526)	θ value	0.21417 (rank : 452)
Query Neighborhood Hits	997	Target Neighborhood Hits	660	Shared Neighborhood Hits	176
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

TRPC3_MOUSE
NC score	0.076317 (rank : 527)	θ value	θ > 10 (rank : 1305)
Query Neighborhood Hits	997	Target Neighborhood Hits	131	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

CS007_HUMAN
NC score	0.076188 (rank : 528)	θ value	8.99809 (rank : 939)
Query Neighborhood Hits	997	Target Neighborhood Hits	401	Shared Neighborhood Hits	148
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

SMR1_MOUSE
NC score	0.075791 (rank : 529)	θ value	θ > 10 (rank : 1269)
Query Neighborhood Hits	997	Target Neighborhood Hits	103	Shared Neighborhood Hits	66
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

MNT_HUMAN
NC score	0.075677 (rank : 530)	θ value	1.38821 (rank : 600)
Query Neighborhood Hits	997	Target Neighborhood Hits	496	Shared Neighborhood Hits	168
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

3BP1_HUMAN
NC score	0.075594 (rank : 531)	θ value	4.03905 (rank : 750)
Query Neighborhood Hits	997	Target Neighborhood Hits	376	Shared Neighborhood Hits	157
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

CD248_HUMAN
NC score	0.075575 (rank : 532)	θ value	0.000786445 (rank : 286)
Query Neighborhood Hits	997	Target Neighborhood Hits	679	Shared Neighborhood Hits	171
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

TRPC6_MOUSE
NC score	0.075393 (rank : 533)	θ value	θ > 10 (rank : 1306)
Query Neighborhood Hits	997	Target Neighborhood Hits	171	Shared Neighborhood Hits	92
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

CECR2_HUMAN
NC score	0.075377 (rank : 534)	θ value	0.00175202 (rank : 298)
Query Neighborhood Hits	997	Target Neighborhood Hits	543	Shared Neighborhood Hits	179
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

ACK1_HUMAN
NC score	0.075273 (rank : 535)	θ value	θ > 10 (rank : 1006)
Query Neighborhood Hits	997	Target Neighborhood Hits	1140	Shared Neighborhood Hits	245
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

CD2_HUMAN
NC score	0.075243 (rank : 536)	θ value	0.62314 (rank : 515)
Query Neighborhood Hits	997	Target Neighborhood Hits	504	Shared Neighborhood Hits	171
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

ACK1_MOUSE
NC score	0.075231 (rank : 537)	θ value	3.0926 (rank : 701)
Query Neighborhood Hits	997	Target Neighborhood Hits	1080	Shared Neighborhood Hits	224
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

M3K11_HUMAN
NC score	0.075157 (rank : 538)	θ value	0.0330416 (rank : 374)
Query Neighborhood Hits	997	Target Neighborhood Hits	1136	Shared Neighborhood Hits	196
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

SELPL_MOUSE
NC score	0.074990 (rank : 539)	θ value	1.81305 (rank : 636)
Query Neighborhood Hits	997	Target Neighborhood Hits	588	Shared Neighborhood Hits	180
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SYNJ1_MOUSE
NC score	0.074958 (rank : 540)	θ value	θ > 10 (rank : 1279)
Query Neighborhood Hits	997	Target Neighborhood Hits	516	Shared Neighborhood Hits	213
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

IWS1_MOUSE
NC score	0.074899 (rank : 541)	θ value	1.06291 (rank : 563)
Query Neighborhood Hits	997	Target Neighborhood Hits	1258	Shared Neighborhood Hits	212
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LARP4_MOUSE
NC score	0.074867 (rank : 542)	θ value	0.0431538 (rank : 385)
Query Neighborhood Hits	997	Target Neighborhood Hits	260	Shared Neighborhood Hits	86
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

PSL1_HUMAN
NC score	0.074612 (rank : 543)	θ value	0.125558 (rank : 425)
Query Neighborhood Hits	997	Target Neighborhood Hits	650	Shared Neighborhood Hits	226
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

SGIP1_HUMAN
NC score	0.074316 (rank : 544)	θ value	θ > 10 (rank : 1263)
Query Neighborhood Hits	997	Target Neighborhood Hits	198	Shared Neighborhood Hits	105
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

WBS14_HUMAN
NC score	0.074223 (rank : 545)	θ value	θ > 10 (rank : 1328)
Query Neighborhood Hits	997	Target Neighborhood Hits	273	Shared Neighborhood Hits	132
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

BAG3_HUMAN
NC score	0.073998 (rank : 546)	θ value	8.99809 (rank : 930)
Query Neighborhood Hits	997	Target Neighborhood Hits	314	Shared Neighborhood Hits	138
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

ZIMP7_MOUSE
NC score	0.073806 (rank : 547)	θ value	0.0113563 (rank : 344)
Query Neighborhood Hits	997	Target Neighborhood Hits	566	Shared Neighborhood Hits	223
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

DGKH_HUMAN
NC score	0.073789 (rank : 548)	θ value	0.0330416 (rank : 371)
Query Neighborhood Hits	997	Target Neighborhood Hits	255	Shared Neighborhood Hits	67
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

CO5A2_HUMAN
NC score	0.073569 (rank : 549)	θ value	1.38821 (rank : 589)
Query Neighborhood Hits	997	Target Neighborhood Hits	760	Shared Neighborhood Hits	238
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

CO3A1_HUMAN
NC score	0.073539 (rank : 550)	θ value	1.06291 (rank : 553)
Query Neighborhood Hits	997	Target Neighborhood Hits	452	Shared Neighborhood Hits	175
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

AFF1_HUMAN
NC score	0.073533 (rank : 551)	θ value	2.36792 (rank : 655)
Query Neighborhood Hits	997	Target Neighborhood Hits	506	Shared Neighborhood Hits	140
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

CO3A1_MOUSE
NC score	0.073520 (rank : 552)	θ value	1.06291 (rank : 554)
Query Neighborhood Hits	997	Target Neighborhood Hits	466	Shared Neighborhood Hits	174
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

PO121_MOUSE
NC score	0.073086 (rank : 553)	θ value	θ > 10 (rank : 1209)
Query Neighborhood Hits	997	Target Neighborhood Hits	345	Shared Neighborhood Hits	120
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

MAP4_MOUSE
NC score	0.072842 (rank : 554)	θ value	θ > 10 (rank : 1164)
Query Neighborhood Hits	997	Target Neighborhood Hits	409	Shared Neighborhood Hits	116
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

CNOT3_MOUSE
NC score	0.072759 (rank : 555)	θ value	5.27518 (rank : 812)
Query Neighborhood Hits	997	Target Neighborhood Hits	504	Shared Neighborhood Hits	136
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

FMN1A_MOUSE
NC score	0.072682 (rank : 556)	θ value	5.27518 (rank : 821)
Query Neighborhood Hits	997	Target Neighborhood Hits	423	Shared Neighborhood Hits	164
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

MEGF9_MOUSE
NC score	0.072634 (rank : 557)	θ value	0.125558 (rank : 424)
Query Neighborhood Hits	997	Target Neighborhood Hits	896	Shared Neighborhood Hits	226
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MKL1_MOUSE
NC score	0.072483 (rank : 558)	θ value	0.21417 (rank : 458)
Query Neighborhood Hits	997	Target Neighborhood Hits	667	Shared Neighborhood Hits	228
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

ALEX_MOUSE
NC score	0.072454 (rank : 559)	θ value	3.0926 (rank : 702)
Query Neighborhood Hits	997	Target Neighborhood Hits	197	Shared Neighborhood Hits	97
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

SF01_HUMAN
NC score	0.072376 (rank : 560)	θ value	θ > 10 (rank : 1259)
Query Neighborhood Hits	997	Target Neighborhood Hits	287	Shared Neighborhood Hits	129
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

CO1A1_MOUSE
NC score	0.072252 (rank : 561)	θ value	5.27518 (rank : 813)
Query Neighborhood Hits	997	Target Neighborhood Hits	457	Shared Neighborhood Hits	176
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO4A5_HUMAN
NC score	0.072073 (rank : 562)	θ value	1.81305 (rank : 615)
Query Neighborhood Hits	997	Target Neighborhood Hits	383	Shared Neighborhood Hits	158
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

TRPC7_HUMAN
NC score	0.072021 (rank : 563)	θ value	θ > 10 (rank : 1307)
Query Neighborhood Hits	997	Target Neighborhood Hits	123	Shared Neighborhood Hits	75
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

RIPK2_HUMAN
NC score	0.071956 (rank : 564)	θ value	θ > 10 (rank : 1234)
Query Neighborhood Hits	997	Target Neighborhood Hits	774	Shared Neighborhood Hits	75
SwissProt Accessions	O43353, Q6UWF0	Gene names	RIPK2, CARDIAK, RICK, RIP2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme- associated kinase) (CARD-containing IL-1 beta ICE-kinase).

CEND1_MOUSE
NC score	0.071942 (rank : 565)	θ value	6.88961 (rank : 867)
Query Neighborhood Hits	997	Target Neighborhood Hits	260	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

RPB1_MOUSE
NC score	0.071912 (rank : 566)	θ value	θ > 10 (rank : 1247)
Query Neighborhood Hits	997	Target Neighborhood Hits	363	Shared Neighborhood Hits	125
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_HUMAN
NC score	0.071705 (rank : 567)	θ value	θ > 10 (rank : 1246)
Query Neighborhood Hits	997	Target Neighborhood Hits	362	Shared Neighborhood Hits	122
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

CNOT3_HUMAN
NC score	0.071578 (rank : 568)	θ value	6.88961 (rank : 869)
Query Neighborhood Hits	997	Target Neighborhood Hits	425	Shared Neighborhood Hits	117
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CO1A1_HUMAN
NC score	0.071536 (rank : 569)	θ value	4.03905 (rank : 766)
Query Neighborhood Hits	997	Target Neighborhood Hits	475	Shared Neighborhood Hits	171
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

WASF3_MOUSE
NC score	0.071466 (rank : 570)	θ value	4.03905 (rank : 805)
Query Neighborhood Hits	997	Target Neighborhood Hits	188	Shared Neighborhood Hits	100
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

ATX2_MOUSE
NC score	0.071363 (rank : 571)	θ value	θ > 10 (rank : 1029)
Query Neighborhood Hits	997	Target Neighborhood Hits	445	Shared Neighborhood Hits	152
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

MINT_HUMAN
NC score	0.071324 (rank : 572)	θ value	θ > 10 (rank : 1176)
Query Neighborhood Hits	997	Target Neighborhood Hits	1291	Shared Neighborhood Hits	257
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

DIAP1_HUMAN
NC score	0.071293 (rank : 573)	θ value	6.88961 (rank : 877)
Query Neighborhood Hits	997	Target Neighborhood Hits	784	Shared Neighborhood Hits	189
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

HRBL_MOUSE
NC score	0.070965 (rank : 574)	θ value	0.163984 (rank : 437)
Query Neighborhood Hits	997	Target Neighborhood Hits	269	Shared Neighborhood Hits	96
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

TRPC5_MOUSE
NC score	0.070942 (rank : 575)	θ value	0.125558 (rank : 431)
Query Neighborhood Hits	997	Target Neighborhood Hits	124	Shared Neighborhood Hits	72
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

TRPC7_MOUSE
NC score	0.070816 (rank : 576)	θ value	θ > 10 (rank : 1308)
Query Neighborhood Hits	997	Target Neighborhood Hits	114	Shared Neighborhood Hits	74
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

ATX2L_MOUSE
NC score	0.070761 (rank : 577)	θ value	0.813845 (rank : 534)
Query Neighborhood Hits	997	Target Neighborhood Hits	401	Shared Neighborhood Hits	146
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

GA2L2_MOUSE
NC score	0.070726 (rank : 578)	θ value	0.00134147 (rank : 294)
Query Neighborhood Hits	997	Target Neighborhood Hits	395	Shared Neighborhood Hits	154
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

FMN2_MOUSE
NC score	0.070668 (rank : 579)	θ value	8.99809 (rank : 947)
Query Neighborhood Hits	997	Target Neighborhood Hits	349	Shared Neighborhood Hits	138
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

MUC5B_HUMAN
NC score	0.070358 (rank : 580)	θ value	θ > 10 (rank : 1186)
Query Neighborhood Hits	997	Target Neighborhood Hits	1020	Shared Neighborhood Hits	200
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

BRD4_HUMAN
NC score	0.070281 (rank : 581)	θ value	θ > 10 (rank : 1042)
Query Neighborhood Hits	997	Target Neighborhood Hits	851	Shared Neighborhood Hits	224
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

TRPC5_HUMAN
NC score	0.069544 (rank : 582)	θ value	0.125558 (rank : 430)
Query Neighborhood Hits	997	Target Neighborhood Hits	122	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

DIAP1_MOUSE
NC score	0.069330 (rank : 583)	θ value	8.99809 (rank : 944)
Query Neighborhood Hits	997	Target Neighborhood Hits	839	Shared Neighborhood Hits	164
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

SPT5H_HUMAN
NC score	0.069296 (rank : 584)	θ value	1.06291 (rank : 578)
Query Neighborhood Hits	997	Target Neighborhood Hits	436	Shared Neighborhood Hits	148
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

VASP_HUMAN
NC score	0.069229 (rank : 585)	θ value	0.163984 (rank : 445)
Query Neighborhood Hits	997	Target Neighborhood Hits	201	Shared Neighborhood Hits	107
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

SPT5H_MOUSE
NC score	0.069044 (rank : 586)	θ value	1.06291 (rank : 579)
Query Neighborhood Hits	997	Target Neighborhood Hits	437	Shared Neighborhood Hits	147
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

MLKL_HUMAN
NC score	0.069009 (rank : 587)	θ value	θ > 10 (rank : 1177)
Query Neighborhood Hits	997	Target Neighborhood Hits	600	Shared Neighborhood Hits	63
SwissProt Accessions	Q8NB16, Q8N6V0	Gene names	MLKL
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

PHLB1_HUMAN
NC score	0.068998 (rank : 588)	θ value	0.0431538 (rank : 387)
Query Neighborhood Hits	997	Target Neighborhood Hits	1038	Shared Neighborhood Hits	191
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

ARI1B_HUMAN
NC score	0.068840 (rank : 589)	θ value	θ > 10 (rank : 1027)
Query Neighborhood Hits	997	Target Neighborhood Hits	567	Shared Neighborhood Hits	204
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

SPR1A_MOUSE
NC score	0.068801 (rank : 590)	θ value	0.365318 (rank : 488)
Query Neighborhood Hits	997	Target Neighborhood Hits	343	Shared Neighborhood Hits	124
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

TM108_HUMAN
NC score	0.068767 (rank : 591)	θ value	θ > 10 (rank : 1299)
Query Neighborhood Hits	997	Target Neighborhood Hits	166	Shared Neighborhood Hits	85
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

COIA1_HUMAN
NC score	0.068678 (rank : 592)	θ value	3.0926 (rank : 716)
Query Neighborhood Hits	997	Target Neighborhood Hits	447	Shared Neighborhood Hits	184
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

SPTA3_MOUSE
NC score	0.068665 (rank : 593)	θ value	θ > 10 (rank : 1271)
Query Neighborhood Hits	997	Target Neighborhood Hits	74	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D9T6, Q80ZS4, Q9D5L5, Q9DAF5	Gene names	Spata3, Tsarg1
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 3 (Testis spermatocyte apoptosis- related protein 1) (Testis and spermatogenesis cell-related protein 1) (mTSARG1).

FMN1B_MOUSE
NC score	0.068592 (rank : 594)	θ value	θ > 10 (rank : 1102)
Query Neighborhood Hits	997	Target Neighborhood Hits	447	Shared Neighborhood Hits	167
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

VASP_MOUSE
NC score	0.068278 (rank : 595)	θ value	6.88961 (rank : 915)
Query Neighborhood Hits	997	Target Neighborhood Hits	195	Shared Neighborhood Hits	91
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

TARA_MOUSE
NC score	0.068061 (rank : 596)	θ value	θ > 10 (rank : 1282)
Query Neighborhood Hits	997	Target Neighborhood Hits	1133	Shared Neighborhood Hits	197
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TIE1_MOUSE
NC score	0.068044 (rank : 597)	θ value	θ > 10 (rank : 1296)
Query Neighborhood Hits	997	Target Neighborhood Hits	1266	Shared Neighborhood Hits	104
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE1_HUMAN
NC score	0.068020 (rank : 598)	θ value	θ > 10 (rank : 1295)
Query Neighborhood Hits	997	Target Neighborhood Hits	1241	Shared Neighborhood Hits	107
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

JPH2_HUMAN
NC score	0.067805 (rank : 599)	θ value	0.125558 (rank : 422)
Query Neighborhood Hits	997	Target Neighborhood Hits	639	Shared Neighborhood Hits	238
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

CO039_HUMAN
NC score	0.067732 (rank : 600)	θ value	θ > 10 (rank : 1060)
Query Neighborhood Hits	997	Target Neighborhood Hits	264	Shared Neighborhood Hits	133
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

WASF3_HUMAN
NC score	0.067731 (rank : 601)	θ value	θ > 10 (rank : 1326)
Query Neighborhood Hits	997	Target Neighborhood Hits	204	Shared Neighborhood Hits	107
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

IRAK3_HUMAN
NC score	0.067451 (rank : 602)	θ value	θ > 10 (rank : 1126)
Query Neighborhood Hits	997	Target Neighborhood Hits	644	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y616	Gene names	IRAK3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

MTSS1_MOUSE
NC score	0.067415 (rank : 603)	θ value	θ > 10 (rank : 1182)
Query Neighborhood Hits	997	Target Neighborhood Hits	592	Shared Neighborhood Hits	209
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

TIE2_MOUSE
NC score	0.067365 (rank : 604)	θ value	θ > 10 (rank : 1298)
Query Neighborhood Hits	997	Target Neighborhood Hits	1204	Shared Neighborhood Hits	99
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

PHC2_HUMAN
NC score	0.067231 (rank : 605)	θ value	0.00228821 (rank : 304)
Query Neighborhood Hits	997	Target Neighborhood Hits	388	Shared Neighborhood Hits	149
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

MILK1_HUMAN
NC score	0.067200 (rank : 606)	θ value	θ > 10 (rank : 1175)
Query Neighborhood Hits	997	Target Neighborhood Hits	427	Shared Neighborhood Hits	157
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

CIZ1_HUMAN
NC score	0.067041 (rank : 607)	θ value	θ > 10 (rank : 1054)
Query Neighborhood Hits	997	Target Neighborhood Hits	359	Shared Neighborhood Hits	102
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

TIE2_HUMAN
NC score	0.067003 (rank : 608)	θ value	θ > 10 (rank : 1297)
Query Neighborhood Hits	997	Target Neighborhood Hits	1192	Shared Neighborhood Hits	100
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TMAP1_HUMAN
NC score	0.066914 (rank : 609)	θ value	θ > 10 (rank : 1300)
Query Neighborhood Hits	997	Target Neighborhood Hits	140	Shared Neighborhood Hits	72
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

AUTS2_HUMAN
NC score	0.066551 (rank : 610)	θ value	8.99809 (rank : 929)
Query Neighborhood Hits	997	Target Neighborhood Hits	342	Shared Neighborhood Hits	130
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

M3K10_HUMAN
NC score	0.066484 (rank : 611)	θ value	θ > 10 (rank : 1153)
Query Neighborhood Hits	997	Target Neighborhood Hits	1071	Shared Neighborhood Hits	144
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

COHA1_MOUSE
NC score	0.066437 (rank : 612)	θ value	0.365318 (rank : 481)
Query Neighborhood Hits	997	Target Neighborhood Hits	414	Shared Neighborhood Hits	159
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

RIPK2_MOUSE
NC score	0.066428 (rank : 613)	θ value	θ > 10 (rank : 1235)
Query Neighborhood Hits	997	Target Neighborhood Hits	776	Shared Neighborhood Hits	74
SwissProt Accessions	P58801	Gene names	Ripk2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1).

CT032_HUMAN
NC score	0.066365 (rank : 614)	θ value	1.38821 (rank : 592)
Query Neighborhood Hits	997	Target Neighborhood Hits	235	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

MNT_MOUSE
NC score	0.066345 (rank : 615)	θ value	8.99809 (rank : 964)
Query Neighborhood Hits	997	Target Neighborhood Hits	432	Shared Neighborhood Hits	137
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

TULP4_HUMAN
NC score	0.066320 (rank : 616)	θ value	0.000270298 (rank : 278)
Query Neighborhood Hits	997	Target Neighborhood Hits	426	Shared Neighborhood Hits	109
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

COHA1_HUMAN
NC score	0.066252 (rank : 617)	θ value	2.36792 (rank : 664)
Query Neighborhood Hits	997	Target Neighborhood Hits	400	Shared Neighborhood Hits	141
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

CD248_MOUSE
NC score	0.066180 (rank : 618)	θ value	0.279714 (rank : 465)
Query Neighborhood Hits	997	Target Neighborhood Hits	578	Shared Neighborhood Hits	157
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

AATK_HUMAN
NC score	0.066088 (rank : 619)	θ value	θ > 10 (rank : 998)
Query Neighborhood Hits	997	Target Neighborhood Hits	1243	Shared Neighborhood Hits	262
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

EFS_HUMAN
NC score	0.066064 (rank : 620)	θ value	θ > 10 (rank : 1077)
Query Neighborhood Hits	997	Target Neighborhood Hits	348	Shared Neighborhood Hits	136
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

EFS_MOUSE
NC score	0.066027 (rank : 621)	θ value	0.813845 (rank : 540)
Query Neighborhood Hits	997	Target Neighborhood Hits	389	Shared Neighborhood Hits	133
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

DMRTD_HUMAN
NC score	0.065939 (rank : 622)	θ value	0.0961366 (rank : 411)
Query Neighborhood Hits	997	Target Neighborhood Hits	216	Shared Neighborhood Hits	99
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

IRAK3_MOUSE
NC score	0.065929 (rank : 623)	θ value	θ > 10 (rank : 1127)
Query Neighborhood Hits	997	Target Neighborhood Hits	628	Shared Neighborhood Hits	70
SwissProt Accessions	Q8K4B2, Q8C7U8, Q8CE40, Q8K1S8	Gene names	Irak3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

PCQAP_MOUSE
NC score	0.065891 (rank : 624)	θ value	θ > 10 (rank : 1201)
Query Neighborhood Hits	997	Target Neighborhood Hits	506	Shared Neighborhood Hits	147
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

MAST4_HUMAN
NC score	0.065860 (rank : 625)	θ value	0.000270298 (rank : 276)
Query Neighborhood Hits	997	Target Neighborhood Hits	1804	Shared Neighborhood Hits	340
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

CSF1_HUMAN
NC score	0.065857 (rank : 626)	θ value	θ > 10 (rank : 1067)
Query Neighborhood Hits	997	Target Neighborhood Hits	258	Shared Neighborhood Hits	109
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

ABL1_MOUSE
NC score	0.065821 (rank : 627)	θ value	θ > 10 (rank : 1001)
Query Neighborhood Hits	997	Target Neighborhood Hits	1178	Shared Neighborhood Hits	196
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

TNK1_HUMAN
NC score	0.065727 (rank : 628)	θ value	θ > 10 (rank : 1301)
Query Neighborhood Hits	997	Target Neighborhood Hits	815	Shared Neighborhood Hits	93
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

IRAK2_HUMAN
NC score	0.065583 (rank : 629)	θ value	2.36792 (rank : 677)
Query Neighborhood Hits	997	Target Neighborhood Hits	714	Shared Neighborhood Hits	83
SwissProt Accessions	O43187	Gene names	IRAK2
Domain Architecture
Description	Interleukin-1 receptor-associated kinase-like 2 (IRAK-2).

MAP1A_HUMAN
NC score	0.065533 (rank : 630)	θ value	0.365318 (rank : 484)
Query Neighborhood Hits	997	Target Neighborhood Hits	1626	Shared Neighborhood Hits	270
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

TF65_HUMAN
NC score	0.065480 (rank : 631)	θ value	θ > 10 (rank : 1292)
Query Neighborhood Hits	997	Target Neighborhood Hits	115	Shared Neighborhood Hits	50
SwissProt Accessions	Q04206, Q6SLK1	Gene names	RELA, NFKB3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

T22D4_HUMAN
NC score	0.065454 (rank : 632)	θ value	0.0113563 (rank : 342)
Query Neighborhood Hits	997	Target Neighborhood Hits	403	Shared Neighborhood Hits	157
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

SYP2L_HUMAN
NC score	0.065448 (rank : 633)	θ value	θ > 10 (rank : 1280)
Query Neighborhood Hits	997	Target Neighborhood Hits	400	Shared Neighborhood Hits	151
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

CO5A1_HUMAN
NC score	0.065419 (rank : 634)	θ value	0.125558 (rank : 418)
Query Neighborhood Hits	997	Target Neighborhood Hits	434	Shared Neighborhood Hits	169
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

IWS1_HUMAN
NC score	0.065122 (rank : 635)	θ value	θ > 10 (rank : 1131)
Query Neighborhood Hits	997	Target Neighborhood Hits	1241	Shared Neighborhood Hits	191
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

M3K9_HUMAN
NC score	0.064923 (rank : 636)	θ value	θ > 10 (rank : 1159)
Query Neighborhood Hits	997	Target Neighborhood Hits	1123	Shared Neighborhood Hits	166
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

ABL1_HUMAN
NC score	0.064921 (rank : 637)	θ value	4.03905 (rank : 752)
Query Neighborhood Hits	997	Target Neighborhood Hits	1220	Shared Neighborhood Hits	193
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

TRPC4_MOUSE
NC score	0.064911 (rank : 638)	θ value	0.813845 (rank : 549)
Query Neighborhood Hits	997	Target Neighborhood Hits	141	Shared Neighborhood Hits	76
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPC4_HUMAN
NC score	0.064793 (rank : 639)	θ value	0.813845 (rank : 548)
Query Neighborhood Hits	997	Target Neighborhood Hits	140	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

KI67_HUMAN
NC score	0.064761 (rank : 640)	θ value	6.88961 (rank : 892)
Query Neighborhood Hits	997	Target Neighborhood Hits	581	Shared Neighborhood Hits	108
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

M3KL4_HUMAN
NC score	0.064665 (rank : 641)	θ value	θ > 10 (rank : 1160)
Query Neighborhood Hits	997	Target Neighborhood Hits	1087	Shared Neighborhood Hits	139
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

RIN3_MOUSE
NC score	0.064642 (rank : 642)	θ value	θ > 10 (rank : 1231)
Query Neighborhood Hits	997	Target Neighborhood Hits	239	Shared Neighborhood Hits	124
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

ERBB2_HUMAN
NC score	0.064181 (rank : 643)	θ value	θ > 10 (rank : 1085)
Query Neighborhood Hits	997	Target Neighborhood Hits	1073	Shared Neighborhood Hits	139
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

PDC6I_MOUSE
NC score	0.064121 (rank : 644)	θ value	0.62314 (rank : 526)
Query Neighborhood Hits	997	Target Neighborhood Hits	275	Shared Neighborhood Hits	106
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

CO4A4_HUMAN
NC score	0.064118 (rank : 645)	θ value	0.47712 (rank : 493)
Query Neighborhood Hits	997	Target Neighborhood Hits	440	Shared Neighborhood Hits	161
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

YES_HUMAN
NC score	0.063996 (rank : 646)	θ value	θ > 10 (rank : 1332)
Query Neighborhood Hits	997	Target Neighborhood Hits	1059	Shared Neighborhood Hits	127
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

FGR_MOUSE
NC score	0.063990 (rank : 647)	θ value	θ > 10 (rank : 1101)
Query Neighborhood Hits	997	Target Neighborhood Hits	1069	Shared Neighborhood Hits	125
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

ERBB4_HUMAN
NC score	0.063958 (rank : 648)	θ value	θ > 10 (rank : 1089)
Query Neighborhood Hits	997	Target Neighborhood Hits	910	Shared Neighborhood Hits	87
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

FYN_MOUSE
NC score	0.063893 (rank : 649)	θ value	θ > 10 (rank : 1105)
Query Neighborhood Hits	997	Target Neighborhood Hits	1073	Shared Neighborhood Hits	124
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

YES_MOUSE
NC score	0.063795 (rank : 650)	θ value	θ > 10 (rank : 1333)
Query Neighborhood Hits	997	Target Neighborhood Hits	1052	Shared Neighborhood Hits	125
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

TXK_HUMAN
NC score	0.063643 (rank : 651)	θ value	θ > 10 (rank : 1313)
Query Neighborhood Hits	997	Target Neighborhood Hits	971	Shared Neighborhood Hits	107
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

FGR_HUMAN
NC score	0.063534 (rank : 652)	θ value	θ > 10 (rank : 1100)
Query Neighborhood Hits	997	Target Neighborhood Hits	1067	Shared Neighborhood Hits	129
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

SMAP1_MOUSE
NC score	0.063531 (rank : 653)	θ value	θ > 10 (rank : 1265)
Query Neighborhood Hits	997	Target Neighborhood Hits	120	Shared Neighborhood Hits	49
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

LAD1_HUMAN
NC score	0.063446 (rank : 654)	θ value	1.81305 (rank : 623)
Query Neighborhood Hits	997	Target Neighborhood Hits	441	Shared Neighborhood Hits	103
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

SREC2_HUMAN
NC score	0.063396 (rank : 655)	θ value	θ > 10 (rank : 1274)
Query Neighborhood Hits	997	Target Neighborhood Hits	645	Shared Neighborhood Hits	129
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

TXK_MOUSE
NC score	0.063383 (rank : 656)	θ value	θ > 10 (rank : 1314)
Query Neighborhood Hits	997	Target Neighborhood Hits	980	Shared Neighborhood Hits	111
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

FYN_HUMAN
NC score	0.063357 (rank : 657)	θ value	θ > 10 (rank : 1104)
Query Neighborhood Hits	997	Target Neighborhood Hits	1078	Shared Neighborhood Hits	126
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

ENAM_MOUSE
NC score	0.063306 (rank : 658)	θ value	0.0563607 (rank : 394)
Query Neighborhood Hits	997	Target Neighborhood Hits	229	Shared Neighborhood Hits	86
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

BTK_HUMAN
NC score	0.063264 (rank : 659)	θ value	θ > 10 (rank : 1044)
Query Neighborhood Hits	997	Target Neighborhood Hits	1026	Shared Neighborhood Hits	124
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

ATX2_HUMAN
NC score	0.063256 (rank : 660)	θ value	θ > 10 (rank : 1028)
Query Neighborhood Hits	997	Target Neighborhood Hits	375	Shared Neighborhood Hits	135
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

CK024_MOUSE
NC score	0.063162 (rank : 661)	θ value	6.88961 (rank : 868)
Query Neighborhood Hits	997	Target Neighborhood Hits	307	Shared Neighborhood Hits	96
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

FAK2_HUMAN
NC score	0.063129 (rank : 662)	θ value	θ > 10 (rank : 1092)
Query Neighborhood Hits	997	Target Neighborhood Hits	847	Shared Neighborhood Hits	80
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

ZAP70_HUMAN
NC score	0.063072 (rank : 663)	θ value	θ > 10 (rank : 1335)
Query Neighborhood Hits	997	Target Neighborhood Hits	893	Shared Neighborhood Hits	88
SwissProt Accessions	P43403	Gene names	ZAP70, SRK
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

CITE4_HUMAN
NC score	0.062903 (rank : 664)	θ value	θ > 10 (rank : 1053)
Query Neighborhood Hits	997	Target Neighborhood Hits	67	Shared Neighborhood Hits	38
SwissProt Accessions	Q96RK1	Gene names	CITED4, MRG2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

CO5A1_MOUSE
NC score	0.062778 (rank : 665)	θ value	0.125558 (rank : 419)
Query Neighborhood Hits	997	Target Neighborhood Hits	419	Shared Neighborhood Hits	166
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

FAK2_MOUSE
NC score	0.062663 (rank : 666)	θ value	θ > 10 (rank : 1093)
Query Neighborhood Hits	997	Target Neighborhood Hits	851	Shared Neighborhood Hits	80
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

BTK_MOUSE
NC score	0.062651 (rank : 667)	θ value	θ > 10 (rank : 1045)
Query Neighborhood Hits	997	Target Neighborhood Hits	1017	Shared Neighborhood Hits	122
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

ERBB2_MOUSE
NC score	0.062634 (rank : 668)	θ value	θ > 10 (rank : 1086)
Query Neighborhood Hits	997	Target Neighborhood Hits	918	Shared Neighborhood Hits	91
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

IRAK1_HUMAN
NC score	0.062599 (rank : 669)	θ value	θ > 10 (rank : 1124)
Query Neighborhood Hits	997	Target Neighborhood Hits	820	Shared Neighborhood Hits	108
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

FAK1_HUMAN
NC score	0.062564 (rank : 670)	θ value	θ > 10 (rank : 1090)
Query Neighborhood Hits	997	Target Neighborhood Hits	850	Shared Neighborhood Hits	87
SwissProt Accessions	Q05397, Q14291, Q9UD85	Gene names	PTK2, FAK, FAK1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2).

FER_HUMAN
NC score	0.062556 (rank : 671)	θ value	θ > 10 (rank : 1094)
Query Neighborhood Hits	997	Target Neighborhood Hits	1278	Shared Neighborhood Hits	112
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

TNK1_MOUSE
NC score	0.062554 (rank : 672)	θ value	θ > 10 (rank : 1302)
Query Neighborhood Hits	997	Target Neighborhood Hits	806	Shared Neighborhood Hits	87
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

SRC_HUMAN
NC score	0.062306 (rank : 673)	θ value	θ > 10 (rank : 1272)
Query Neighborhood Hits	997	Target Neighborhood Hits	1058	Shared Neighborhood Hits	125
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

FAK1_MOUSE
NC score	0.062235 (rank : 674)	θ value	θ > 10 (rank : 1091)
Query Neighborhood Hits	997	Target Neighborhood Hits	850	Shared Neighborhood Hits	82
SwissProt Accessions	P34152, O08578	Gene names	Ptk2, Fadk, Fak, Fak1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK).

MLKL_MOUSE
NC score	0.062174 (rank : 675)	θ value	θ > 10 (rank : 1178)
Query Neighborhood Hits	997	Target Neighborhood Hits	707	Shared Neighborhood Hits	71
SwissProt Accessions	Q9D2Y4, Q8CIJ5	Gene names	Mlkl
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

FRK_HUMAN
NC score	0.062067 (rank : 676)	θ value	θ > 10 (rank : 1103)
Query Neighborhood Hits	997	Target Neighborhood Hits	1058	Shared Neighborhood Hits	120
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

ZAP70_MOUSE
NC score	0.062049 (rank : 677)	θ value	θ > 10 (rank : 1336)
Query Neighborhood Hits	997	Target Neighborhood Hits	905	Shared Neighborhood Hits	88
SwissProt Accessions	P43404	Gene names	Zap70, Srk, Zap-70
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

RIPK3_HUMAN
NC score	0.061973 (rank : 678)	θ value	θ > 10 (rank : 1236)
Query Neighborhood Hits	997	Target Neighborhood Hits	828	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Y572	Gene names	RIPK3, RIP3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3).

TEC_HUMAN
NC score	0.061891 (rank : 679)	θ value	θ > 10 (rank : 1286)
Query Neighborhood Hits	997	Target Neighborhood Hits	1006	Shared Neighborhood Hits	111
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

SRC_MOUSE
NC score	0.061860 (rank : 680)	θ value	θ > 10 (rank : 1273)
Query Neighborhood Hits	997	Target Neighborhood Hits	1033	Shared Neighborhood Hits	124
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

COGA1_HUMAN
NC score	0.061613 (rank : 681)	θ value	θ > 10 (rank : 1065)
Query Neighborhood Hits	997	Target Neighborhood Hits	345	Shared Neighborhood Hits	143
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

HCK_MOUSE
NC score	0.061566 (rank : 682)	θ value	θ > 10 (rank : 1114)
Query Neighborhood Hits	997	Target Neighborhood Hits	1029	Shared Neighborhood Hits	121
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

DDR1_HUMAN
NC score	0.061521 (rank : 683)	θ value	θ > 10 (rank : 1072)
Query Neighborhood Hits	997	Target Neighborhood Hits	819	Shared Neighborhood Hits	79
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

ROR2_MOUSE
NC score	0.061458 (rank : 684)	θ value	θ > 10 (rank : 1243)
Query Neighborhood Hits	997	Target Neighborhood Hits	1000	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Z138	Gene names	Ror2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2).

CRSP2_HUMAN
NC score	0.061441 (rank : 685)	θ value	2.36792 (rank : 665)
Query Neighborhood Hits	997	Target Neighborhood Hits	380	Shared Neighborhood Hits	144
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

HCK_HUMAN
NC score	0.061388 (rank : 686)	θ value	θ > 10 (rank : 1113)
Query Neighborhood Hits	997	Target Neighborhood Hits	1035	Shared Neighborhood Hits	123
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

NELFA_MOUSE
NC score	0.061347 (rank : 687)	θ value	θ > 10 (rank : 1191)
Query Neighborhood Hits	997	Target Neighborhood Hits	195	Shared Neighborhood Hits	102
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

COBA1_HUMAN
NC score	0.061272 (rank : 688)	θ value	0.365318 (rank : 480)
Query Neighborhood Hits	997	Target Neighborhood Hits	491	Shared Neighborhood Hits	170
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

LTK_HUMAN
NC score	0.061230 (rank : 689)	θ value	θ > 10 (rank : 1149)
Query Neighborhood Hits	997	Target Neighborhood Hits	774	Shared Neighborhood Hits	79
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

DDR1_MOUSE
NC score	0.061196 (rank : 690)	θ value	θ > 10 (rank : 1073)
Query Neighborhood Hits	997	Target Neighborhood Hits	818	Shared Neighborhood Hits	79
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

ITK_HUMAN
NC score	0.061178 (rank : 691)	θ value	θ > 10 (rank : 1129)
Query Neighborhood Hits	997	Target Neighborhood Hits	1016	Shared Neighborhood Hits	109
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

EGFR_HUMAN
NC score	0.061030 (rank : 692)	θ value	θ > 10 (rank : 1078)
Query Neighborhood Hits	997	Target Neighborhood Hits	939	Shared Neighborhood Hits	81
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

CO7A1_HUMAN
NC score	0.061014 (rank : 693)	θ value	4.03905 (rank : 769)
Query Neighborhood Hits	997	Target Neighborhood Hits	807	Shared Neighborhood Hits	226
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

LCK_MOUSE
NC score	0.061004 (rank : 694)	θ value	θ > 10 (rank : 1147)
Query Neighborhood Hits	997	Target Neighborhood Hits	981	Shared Neighborhood Hits	105
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

TEC_MOUSE
NC score	0.060994 (rank : 695)	θ value	θ > 10 (rank : 1287)
Query Neighborhood Hits	997	Target Neighborhood Hits	1006	Shared Neighborhood Hits	111
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TRDN_HUMAN
NC score	0.060958 (rank : 696)	θ value	θ > 10 (rank : 1304)
Query Neighborhood Hits	997	Target Neighborhood Hits	542	Shared Neighborhood Hits	70
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

RIPK3_MOUSE
NC score	0.060914 (rank : 697)	θ value	θ > 10 (rank : 1237)
Query Neighborhood Hits	997	Target Neighborhood Hits	867	Shared Neighborhood Hits	99
SwissProt Accessions	Q9QZL0	Gene names	Ripk3, Rip3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3).

EGFR_MOUSE
NC score	0.060893 (rank : 698)	θ value	θ > 10 (rank : 1079)
Query Neighborhood Hits	997	Target Neighborhood Hits	927	Shared Neighborhood Hits	81
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

LTK_MOUSE
NC score	0.060893 (rank : 699)	θ value	θ > 10 (rank : 1150)
Query Neighborhood Hits	997	Target Neighborhood Hits	770	Shared Neighborhood Hits	80
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

STAC_MOUSE
NC score	0.060888 (rank : 700)	θ value	0.21417 (rank : 461)
Query Neighborhood Hits	997	Target Neighborhood Hits	268	Shared Neighborhood Hits	67
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

AATK_MOUSE
NC score	0.060790 (rank : 701)	θ value	θ > 10 (rank : 999)
Query Neighborhood Hits	997	Target Neighborhood Hits	942	Shared Neighborhood Hits	144
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

ROR1_HUMAN
NC score	0.060775 (rank : 702)	θ value	θ > 10 (rank : 1240)
Query Neighborhood Hits	997	Target Neighborhood Hits	1018	Shared Neighborhood Hits	82
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

INSR_HUMAN
NC score	0.060762 (rank : 703)	θ value	θ > 10 (rank : 1122)
Query Neighborhood Hits	997	Target Neighborhood Hits	963	Shared Neighborhood Hits	84
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

ROR1_MOUSE
NC score	0.060746 (rank : 704)	θ value	θ > 10 (rank : 1241)
Query Neighborhood Hits	997	Target Neighborhood Hits	1025	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Z139	Gene names	Ror1, Ntrkr1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1).

TP53B_MOUSE
NC score	0.060668 (rank : 705)	θ value	6.88961 (rank : 910)
Query Neighborhood Hits	997	Target Neighborhood Hits	644	Shared Neighborhood Hits	147
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

STAC_HUMAN
NC score	0.060668 (rank : 706)	θ value	0.163984 (rank : 443)
Query Neighborhood Hits	997	Target Neighborhood Hits	276	Shared Neighborhood Hits	65
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

SF01_MOUSE
NC score	0.060616 (rank : 707)	θ value	θ > 10 (rank : 1260)
Query Neighborhood Hits	997	Target Neighborhood Hits	240	Shared Neighborhood Hits	101
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

ITK_MOUSE
NC score	0.060604 (rank : 708)	θ value	θ > 10 (rank : 1130)
Query Neighborhood Hits	997	Target Neighborhood Hits	985	Shared Neighborhood Hits	105
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

SMAP1_HUMAN
NC score	0.060595 (rank : 709)	θ value	θ > 10 (rank : 1264)
Query Neighborhood Hits	997	Target Neighborhood Hits	98	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

CASL_MOUSE
NC score	0.060552 (rank : 710)	θ value	0.0431538 (rank : 378)
Query Neighborhood Hits	997	Target Neighborhood Hits	225	Shared Neighborhood Hits	69
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

ROR2_HUMAN
NC score	0.060552 (rank : 711)	θ value	θ > 10 (rank : 1242)
Query Neighborhood Hits	997	Target Neighborhood Hits	1014	Shared Neighborhood Hits	83
SwissProt Accessions	Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61	Gene names	ROR2, NTRKR2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2).

MET_HUMAN
NC score	0.060523 (rank : 712)	θ value	θ > 10 (rank : 1173)
Query Neighborhood Hits	997	Target Neighborhood Hits	831	Shared Neighborhood Hits	77
SwissProt Accessions	P08581, O60366, Q12875, Q9UDX7, Q9UPL8	Gene names	MET
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

ATX7_HUMAN
NC score	0.060491 (rank : 713)	θ value	0.125558 (rank : 417)
Query Neighborhood Hits	997	Target Neighborhood Hits	351	Shared Neighborhood Hits	130
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

LCK_HUMAN
NC score	0.060444 (rank : 714)	θ value	θ > 10 (rank : 1146)
Query Neighborhood Hits	997	Target Neighborhood Hits	987	Shared Neighborhood Hits	106
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

ATX7_MOUSE
NC score	0.060390 (rank : 715)	θ value	3.0926 (rank : 705)
Query Neighborhood Hits	997	Target Neighborhood Hits	328	Shared Neighborhood Hits	142
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

WNK4_HUMAN
NC score	0.060386 (rank : 716)	θ value	θ > 10 (rank : 1330)
Query Neighborhood Hits	997	Target Neighborhood Hits	1043	Shared Neighborhood Hits	206
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

KSYK_MOUSE
NC score	0.060332 (rank : 717)	θ value	θ > 10 (rank : 1143)
Query Neighborhood Hits	997	Target Neighborhood Hits	944	Shared Neighborhood Hits	101
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

MET_MOUSE
NC score	0.060310 (rank : 718)	θ value	θ > 10 (rank : 1174)
Query Neighborhood Hits	997	Target Neighborhood Hits	844	Shared Neighborhood Hits	80
SwissProt Accessions	P16056, Q62125	Gene names	Met
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

TCRG1_MOUSE
NC score	0.060256 (rank : 719)	θ value	θ > 10 (rank : 1285)
Query Neighborhood Hits	997	Target Neighborhood Hits	947	Shared Neighborhood Hits	164
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

INSRR_HUMAN
NC score	0.060232 (rank : 720)	θ value	θ > 10 (rank : 1120)
Query Neighborhood Hits	997	Target Neighborhood Hits	950	Shared Neighborhood Hits	93
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

INSRR_MOUSE
NC score	0.060228 (rank : 721)	θ value	θ > 10 (rank : 1121)
Query Neighborhood Hits	997	Target Neighborhood Hits	961	Shared Neighborhood Hits	92
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

PTK6_MOUSE
NC score	0.060053 (rank : 722)	θ value	θ > 10 (rank : 1219)
Query Neighborhood Hits	997	Target Neighborhood Hits	1026	Shared Neighborhood Hits	116
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

LYN_MOUSE
NC score	0.060046 (rank : 723)	θ value	θ > 10 (rank : 1152)
Query Neighborhood Hits	997	Target Neighborhood Hits	1023	Shared Neighborhood Hits	123
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

BLK_HUMAN
NC score	0.059974 (rank : 724)	θ value	θ > 10 (rank : 1035)
Query Neighborhood Hits	997	Target Neighborhood Hits	994	Shared Neighborhood Hits	114
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

LYN_HUMAN
NC score	0.059896 (rank : 725)	θ value	θ > 10 (rank : 1151)
Query Neighborhood Hits	997	Target Neighborhood Hits	1022	Shared Neighborhood Hits	120
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

FES_MOUSE
NC score	0.059841 (rank : 726)	θ value	θ > 10 (rank : 1096)
Query Neighborhood Hits	997	Target Neighborhood Hits	980	Shared Neighborhood Hits	99
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

RIMB1_HUMAN
NC score	0.059829 (rank : 727)	θ value	1.06291 (rank : 577)
Query Neighborhood Hits	997	Target Neighborhood Hits	1479	Shared Neighborhood Hits	250
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

GUC2G_MOUSE
NC score	0.059788 (rank : 728)	θ value	θ > 10 (rank : 1112)
Query Neighborhood Hits	997	Target Neighborhood Hits	644	Shared Neighborhood Hits	67
SwissProt Accessions	Q6TL19, Q8BWU7	Gene names	Gucy2g
Domain Architecture	No domain graphic available
Description	Guanylate cyclase 2G precursor (EC 4.6.1.2) (Guanylyl cyclase receptor G) (mGC-G).

COBA1_MOUSE
NC score	0.059745 (rank : 729)	θ value	0.62314 (rank : 517)
Query Neighborhood Hits	997	Target Neighborhood Hits	487	Shared Neighborhood Hits	171
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

INSR_MOUSE
NC score	0.059742 (rank : 730)	θ value	θ > 10 (rank : 1123)
Query Neighborhood Hits	997	Target Neighborhood Hits	968	Shared Neighborhood Hits	83
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

DDR2_HUMAN
NC score	0.059682 (rank : 731)	θ value	θ > 10 (rank : 1074)
Query Neighborhood Hits	997	Target Neighborhood Hits	818	Shared Neighborhood Hits	76
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

BIN1_HUMAN
NC score	0.059660 (rank : 732)	θ value	0.0113563 (rank : 338)
Query Neighborhood Hits	997	Target Neighborhood Hits	335	Shared Neighborhood Hits	103
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

PTK6_HUMAN
NC score	0.059551 (rank : 733)	θ value	θ > 10 (rank : 1218)
Query Neighborhood Hits	997	Target Neighborhood Hits	1020	Shared Neighborhood Hits	116
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

MATK_HUMAN
NC score	0.059520 (rank : 734)	θ value	θ > 10 (rank : 1166)
Query Neighborhood Hits	997	Target Neighborhood Hits	954	Shared Neighborhood Hits	101
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

KSYK_HUMAN
NC score	0.059462 (rank : 735)	θ value	θ > 10 (rank : 1142)
Query Neighborhood Hits	997	Target Neighborhood Hits	901	Shared Neighborhood Hits	85
SwissProt Accessions	P43405	Gene names	SYK
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

ALK_MOUSE
NC score	0.059435 (rank : 736)	θ value	θ > 10 (rank : 1009)
Query Neighborhood Hits	997	Target Neighborhood Hits	811	Shared Neighborhood Hits	86
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

RYK_HUMAN
NC score	0.059375 (rank : 737)	θ value	θ > 10 (rank : 1249)
Query Neighborhood Hits	997	Target Neighborhood Hits	701	Shared Neighborhood Hits	69
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

DDR2_MOUSE
NC score	0.059332 (rank : 738)	θ value	θ > 10 (rank : 1075)
Query Neighborhood Hits	997	Target Neighborhood Hits	813	Shared Neighborhood Hits	78
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

ROS_HUMAN
NC score	0.059290 (rank : 739)	θ value	θ > 10 (rank : 1244)
Query Neighborhood Hits	997	Target Neighborhood Hits	907	Shared Neighborhood Hits	85
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

MATK_MOUSE
NC score	0.059235 (rank : 740)	θ value	θ > 10 (rank : 1167)
Query Neighborhood Hits	997	Target Neighborhood Hits	952	Shared Neighborhood Hits	102
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

M3K7_MOUSE
NC score	0.059234 (rank : 741)	θ value	θ > 10 (rank : 1158)
Query Neighborhood Hits	997	Target Neighborhood Hits	892	Shared Neighborhood Hits	79
SwissProt Accessions	Q62073	Gene names	Map3k7, Tak1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

AFF1_MOUSE
NC score	0.059210 (rank : 742)	θ value	θ > 10 (rank : 1007)
Query Neighborhood Hits	997	Target Neighborhood Hits	351	Shared Neighborhood Hits	121
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

M3K7_HUMAN
NC score	0.059200 (rank : 743)	θ value	θ > 10 (rank : 1157)
Query Neighborhood Hits	997	Target Neighborhood Hits	892	Shared Neighborhood Hits	79
SwissProt Accessions	O43318, O43317, O43319, Q5TDN2, Q5TDN3	Gene names	MAP3K7, TAK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

COBA2_HUMAN
NC score	0.059143 (rank : 744)	θ value	4.03905 (rank : 770)
Query Neighborhood Hits	997	Target Neighborhood Hits	408	Shared Neighborhood Hits	149
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

BLK_MOUSE
NC score	0.059078 (rank : 745)	θ value	θ > 10 (rank : 1036)
Query Neighborhood Hits	997	Target Neighborhood Hits	992	Shared Neighborhood Hits	110
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

MERTK_HUMAN
NC score	0.059074 (rank : 746)	θ value	θ > 10 (rank : 1171)
Query Neighborhood Hits	997	Target Neighborhood Hits	988	Shared Neighborhood Hits	86
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

SAM14_MOUSE
NC score	0.058981 (rank : 747)	θ value	θ > 10 (rank : 1253)
Query Neighborhood Hits	997	Target Neighborhood Hits	91	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K070, Q5SWB7, Q8BHE2, Q8C8N5	Gene names	Samd14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

RYK_MOUSE
NC score	0.058961 (rank : 748)	θ value	θ > 10 (rank : 1250)
Query Neighborhood Hits	997	Target Neighborhood Hits	715	Shared Neighborhood Hits	71
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

NELFA_HUMAN
NC score	0.058953 (rank : 749)	θ value	θ > 10 (rank : 1190)
Query Neighborhood Hits	997	Target Neighborhood Hits	161	Shared Neighborhood Hits	89
SwissProt Accessions	Q9H3P2, O95392	Gene names	WHSC2, NELFA
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein).

FES_HUMAN
NC score	0.058953 (rank : 750)	θ value	θ > 10 (rank : 1095)
Query Neighborhood Hits	997	Target Neighborhood Hits	978	Shared Neighborhood Hits	87
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

UFO_MOUSE
NC score	0.058924 (rank : 751)	θ value	θ > 10 (rank : 1320)
Query Neighborhood Hits	997	Target Neighborhood Hits	988	Shared Neighborhood Hits	84
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

MERTK_MOUSE
NC score	0.058862 (rank : 752)	θ value	θ > 10 (rank : 1172)
Query Neighborhood Hits	997	Target Neighborhood Hits	974	Shared Neighborhood Hits	82
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

SPRR3_HUMAN
NC score	0.058853 (rank : 753)	θ value	8.99809 (rank : 981)
Query Neighborhood Hits	997	Target Neighborhood Hits	102	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

MAVS_HUMAN
NC score	0.058756 (rank : 754)	θ value	θ > 10 (rank : 1168)
Query Neighborhood Hits	997	Target Neighborhood Hits	271	Shared Neighborhood Hits	97
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

BMX_MOUSE
NC score	0.058741 (rank : 755)	θ value	θ > 10 (rank : 1040)
Query Neighborhood Hits	997	Target Neighborhood Hits	912	Shared Neighborhood Hits	93
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

ALK_HUMAN
NC score	0.058678 (rank : 756)	θ value	θ > 10 (rank : 1008)
Query Neighborhood Hits	997	Target Neighborhood Hits	795	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

ABL2_HUMAN
NC score	0.058677 (rank : 757)	θ value	θ > 10 (rank : 1002)
Query Neighborhood Hits	997	Target Neighborhood Hits	1045	Shared Neighborhood Hits	123
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

UFO_HUMAN
NC score	0.058628 (rank : 758)	θ value	θ > 10 (rank : 1319)
Query Neighborhood Hits	997	Target Neighborhood Hits	981	Shared Neighborhood Hits	88
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

HSF1_MOUSE
NC score	0.058617 (rank : 759)	θ value	0.00102713 (rank : 291)
Query Neighborhood Hits	997	Target Neighborhood Hits	267	Shared Neighborhood Hits	78
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

SMP1L_HUMAN
NC score	0.058585 (rank : 760)	θ value	θ > 10 (rank : 1267)
Query Neighborhood Hits	997	Target Neighborhood Hits	74	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

IF35_MOUSE
NC score	0.058475 (rank : 761)	θ value	θ > 10 (rank : 1115)
Query Neighborhood Hits	997	Target Neighborhood Hits	210	Shared Neighborhood Hits	116
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

CSK_HUMAN
NC score	0.058394 (rank : 762)	θ value	θ > 10 (rank : 1068)
Query Neighborhood Hits	997	Target Neighborhood Hits	1009	Shared Neighborhood Hits	107
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

NTRK1_HUMAN
NC score	0.058357 (rank : 763)	θ value	θ > 10 (rank : 1194)
Query Neighborhood Hits	997	Target Neighborhood Hits	1023	Shared Neighborhood Hits	76
SwissProt Accessions	P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7	Gene names	NTRK1, TRK
Domain Architecture
Description	High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A).

BMX_HUMAN
NC score	0.058275 (rank : 764)	θ value	θ > 10 (rank : 1039)
Query Neighborhood Hits	997	Target Neighborhood Hits	942	Shared Neighborhood Hits	95
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

IGF1R_MOUSE
NC score	0.058259 (rank : 765)	θ value	θ > 10 (rank : 1119)
Query Neighborhood Hits	997	Target Neighborhood Hits	973	Shared Neighborhood Hits	89
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

PTN23_HUMAN
NC score	0.058244 (rank : 766)	θ value	4.03905 (rank : 789)
Query Neighborhood Hits	997	Target Neighborhood Hits	646	Shared Neighborhood Hits	198
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

RON_MOUSE
NC score	0.058210 (rank : 767)	θ value	θ > 10 (rank : 1239)
Query Neighborhood Hits	997	Target Neighborhood Hits	836	Shared Neighborhood Hits	78
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

ZIM10_HUMAN
NC score	0.058020 (rank : 768)	θ value	θ > 10 (rank : 1337)
Query Neighborhood Hits	997	Target Neighborhood Hits	577	Shared Neighborhood Hits	208
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

RON_HUMAN
NC score	0.057990 (rank : 769)	θ value	θ > 10 (rank : 1238)
Query Neighborhood Hits	997	Target Neighborhood Hits	842	Shared Neighborhood Hits	81
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

PDC6I_HUMAN
NC score	0.057954 (rank : 770)	θ value	θ > 10 (rank : 1202)
Query Neighborhood Hits	997	Target Neighborhood Hits	278	Shared Neighborhood Hits	128
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

TCRG1_HUMAN
NC score	0.057946 (rank : 771)	θ value	8.99809 (rank : 989)
Query Neighborhood Hits	997	Target Neighborhood Hits	929	Shared Neighborhood Hits	150
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

IGF1R_HUMAN
NC score	0.057894 (rank : 772)	θ value	θ > 10 (rank : 1118)
Query Neighborhood Hits	997	Target Neighborhood Hits	977	Shared Neighborhood Hits	86
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

MLTK_HUMAN
NC score	0.057889 (rank : 773)	θ value	θ > 10 (rank : 1179)
Query Neighborhood Hits	997	Target Neighborhood Hits	911	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NYL2, Q53SX1, Q580W8, Q59GY5, Q86YW8, Q9HCC4, Q9HCC5, Q9HDD2, Q9NYE9	Gene names	MLTK, ZAK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Cervical cancer suppressor gene 4 protein).

SH3K1_HUMAN
NC score	0.057862 (rank : 774)	θ value	5.27518 (rank : 843)
Query Neighborhood Hits	997	Target Neighborhood Hits	341	Shared Neighborhood Hits	92
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

M3K12_HUMAN
NC score	0.057856 (rank : 775)	θ value	θ > 10 (rank : 1154)
Query Neighborhood Hits	997	Target Neighborhood Hits	940	Shared Neighborhood Hits	121
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

TYRO3_MOUSE
NC score	0.057830 (rank : 776)	θ value	θ > 10 (rank : 1318)
Query Neighborhood Hits	997	Target Neighborhood Hits	1007	Shared Neighborhood Hits	82
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

SRMS_HUMAN
NC score	0.057682 (rank : 777)	θ value	θ > 10 (rank : 1276)
Query Neighborhood Hits	997	Target Neighborhood Hits	946	Shared Neighborhood Hits	95
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

CO4A1_MOUSE
NC score	0.057659 (rank : 778)	θ value	1.06291 (rank : 555)
Query Neighborhood Hits	997	Target Neighborhood Hits	450	Shared Neighborhood Hits	173
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

MLTK_MOUSE
NC score	0.057619 (rank : 779)	θ value	θ > 10 (rank : 1180)
Query Neighborhood Hits	997	Target Neighborhood Hits	874	Shared Neighborhood Hits	85
SwissProt Accessions	Q9ESL4, Q3V1X8, Q8BR73, Q9ESL3	Gene names	Mltk
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK).

CO1A2_MOUSE
NC score	0.057569 (rank : 780)	θ value	1.81305 (rank : 614)
Query Neighborhood Hits	997	Target Neighborhood Hits	388	Shared Neighborhood Hits	143
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

RAF1_HUMAN
NC score	0.057529 (rank : 781)	θ value	θ > 10 (rank : 1222)
Query Neighborhood Hits	997	Target Neighborhood Hits	886	Shared Neighborhood Hits	85
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

GUC2C_HUMAN
NC score	0.057503 (rank : 782)	θ value	θ > 10 (rank : 1109)
Query Neighborhood Hits	997	Target Neighborhood Hits	624	Shared Neighborhood Hits	64
SwissProt Accessions	P25092	Gene names	GUCY2C, GUC2C, STAR
Domain Architecture
Description	Heat-stable enterotoxin receptor precursor (GC-C) (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR).

RAF1_MOUSE
NC score	0.057497 (rank : 783)	θ value	θ > 10 (rank : 1223)
Query Neighborhood Hits	997	Target Neighborhood Hits	886	Shared Neighborhood Hits	85
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

TYRO3_HUMAN
NC score	0.057399 (rank : 784)	θ value	θ > 10 (rank : 1317)
Query Neighborhood Hits	997	Target Neighborhood Hits	995	Shared Neighborhood Hits	79
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

RET_MOUSE
NC score	0.057398 (rank : 785)	θ value	θ > 10 (rank : 1230)
Query Neighborhood Hits	997	Target Neighborhood Hits	884	Shared Neighborhood Hits	79
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

CSK_MOUSE
NC score	0.057391 (rank : 786)	θ value	θ > 10 (rank : 1069)
Query Neighborhood Hits	997	Target Neighborhood Hits	1009	Shared Neighborhood Hits	107
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

BRAF1_HUMAN
NC score	0.057318 (rank : 787)	θ value	θ > 10 (rank : 1041)
Query Neighborhood Hits	997	Target Neighborhood Hits	883	Shared Neighborhood Hits	88
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

PS1C2_HUMAN
NC score	0.057307 (rank : 788)	θ value	θ > 10 (rank : 1217)
Query Neighborhood Hits	997	Target Neighborhood Hits	66	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UIG4	Gene names	PSORS1C2, C6orf17, SPR1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein precursor (SPR1 protein).

M3K12_MOUSE
NC score	0.057264 (rank : 789)	θ value	θ > 10 (rank : 1155)
Query Neighborhood Hits	997	Target Neighborhood Hits	957	Shared Neighborhood Hits	113
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

SRMS_MOUSE
NC score	0.057250 (rank : 790)	θ value	θ > 10 (rank : 1277)
Query Neighborhood Hits	997	Target Neighborhood Hits	964	Shared Neighborhood Hits	97
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

SYN2_HUMAN
NC score	0.057219 (rank : 791)	θ value	3.0926 (rank : 742)
Query Neighborhood Hits	997	Target Neighborhood Hits	213	Shared Neighborhood Hits	115
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

RET_HUMAN
NC score	0.057112 (rank : 792)	θ value	θ > 10 (rank : 1229)
Query Neighborhood Hits	997	Target Neighborhood Hits	873	Shared Neighborhood Hits	76
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

ERBB3_HUMAN
NC score	0.056985 (rank : 793)	θ value	θ > 10 (rank : 1087)
Query Neighborhood Hits	997	Target Neighborhood Hits	918	Shared Neighborhood Hits	83
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

SMP1L_MOUSE
NC score	0.056944 (rank : 794)	θ value	θ > 10 (rank : 1268)
Query Neighborhood Hits	997	Target Neighborhood Hits	70	Shared Neighborhood Hits	34
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

LTBP4_MOUSE
NC score	0.056782 (rank : 795)	θ value	3.0926 (rank : 725)
Query Neighborhood Hits	997	Target Neighborhood Hits	607	Shared Neighborhood Hits	109
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

VCX3_HUMAN
NC score	0.056778 (rank : 796)	θ value	θ > 10 (rank : 1322)
Query Neighborhood Hits	997	Target Neighborhood Hits	105	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

IRAK1_MOUSE
NC score	0.056652 (rank : 797)	θ value	θ > 10 (rank : 1125)
Query Neighborhood Hits	997	Target Neighborhood Hits	784	Shared Neighborhood Hits	86
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

MEGF9_HUMAN
NC score	0.056619 (rank : 798)	θ value	θ > 10 (rank : 1170)
Query Neighborhood Hits	997	Target Neighborhood Hits	557	Shared Neighborhood Hits	136
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

ERBB3_MOUSE
NC score	0.056370 (rank : 799)	θ value	θ > 10 (rank : 1088)
Query Neighborhood Hits	997	Target Neighborhood Hits	898	Shared Neighborhood Hits	84
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

COIA1_MOUSE
NC score	0.056348 (rank : 800)	θ value	1.06291 (rank : 557)
Query Neighborhood Hits	997	Target Neighborhood Hits	481	Shared Neighborhood Hits	164
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

SAM14_HUMAN
NC score	0.056190 (rank : 801)	θ value	θ > 10 (rank : 1252)
Query Neighborhood Hits	997	Target Neighborhood Hits	81	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IZD0, Q8N2X0	Gene names	SAMD14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

ARAF_HUMAN
NC score	0.056123 (rank : 802)	θ value	θ > 10 (rank : 1021)
Query Neighborhood Hits	997	Target Neighborhood Hits	924	Shared Neighborhood Hits	98
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

ENL_HUMAN
NC score	0.056056 (rank : 803)	θ value	θ > 10 (rank : 1083)
Query Neighborhood Hits	997	Target Neighborhood Hits	305	Shared Neighborhood Hits	93
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

RFX1_HUMAN
NC score	0.056036 (rank : 804)	θ value	0.125558 (rank : 426)
Query Neighborhood Hits	997	Target Neighborhood Hits	256	Shared Neighborhood Hits	123
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

GUC2F_HUMAN
NC score	0.056028 (rank : 805)	θ value	θ > 10 (rank : 1111)
Query Neighborhood Hits	997	Target Neighborhood Hits	740	Shared Neighborhood Hits	69
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

IF4G1_MOUSE
NC score	0.055912 (rank : 806)	θ value	θ > 10 (rank : 1117)
Query Neighborhood Hits	997	Target Neighborhood Hits	534	Shared Neighborhood Hits	185
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

SREC2_MOUSE
NC score	0.055801 (rank : 807)	θ value	θ > 10 (rank : 1275)
Query Neighborhood Hits	997	Target Neighborhood Hits	605	Shared Neighborhood Hits	109
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

NFRKB_MOUSE
NC score	0.055788 (rank : 808)	θ value	2.36792 (rank : 684)
Query Neighborhood Hits	997	Target Neighborhood Hits	393	Shared Neighborhood Hits	121
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

ARMX2_MOUSE
NC score	0.055604 (rank : 809)	θ value	0.62314 (rank : 514)
Query Neighborhood Hits	997	Target Neighborhood Hits	349	Shared Neighborhood Hits	136
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

GNAS1_MOUSE
NC score	0.055602 (rank : 810)	θ value	0.21417 (rank : 453)
Query Neighborhood Hits	997	Target Neighborhood Hits	651	Shared Neighborhood Hits	215
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

NTRK3_HUMAN
NC score	0.055522 (rank : 811)	θ value	θ > 10 (rank : 1197)
Query Neighborhood Hits	997	Target Neighborhood Hits	1115	Shared Neighborhood Hits	82
SwissProt Accessions	Q16288, Q12827, Q16289	Gene names	NTRK3, TRKC
Domain Architecture
Description	NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C).

ARAF_MOUSE
NC score	0.055343 (rank : 812)	θ value	θ > 10 (rank : 1022)
Query Neighborhood Hits	997	Target Neighborhood Hits	874	Shared Neighborhood Hits	82
SwissProt Accessions	P04627, Q99J44, Q9CTT5, Q9D6R6, Q9DBU7	Gene names	Araf, A-raf, Araf1
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1).

CENA1_HUMAN
NC score	0.055331 (rank : 813)	θ value	θ > 10 (rank : 1048)
Query Neighborhood Hits	997	Target Neighborhood Hits	87	Shared Neighborhood Hits	29
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

AN13D_MOUSE
NC score	0.055215 (rank : 814)	θ value	θ > 10 (rank : 1013)
Query Neighborhood Hits	997	Target Neighborhood Hits	22	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PD24	Gene names	Ankrd13d
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13D.

ULK1_MOUSE
NC score	0.055168 (rank : 815)	θ value	0.00298849 (rank : 314)
Query Neighborhood Hits	997	Target Neighborhood Hits	1214	Shared Neighborhood Hits	226
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

NTRK2_HUMAN
NC score	0.055131 (rank : 816)	θ value	θ > 10 (rank : 1195)
Query Neighborhood Hits	997	Target Neighborhood Hits	1081	Shared Neighborhood Hits	79
SwissProt Accessions	Q16620, Q16675, Q8WXJ6	Gene names	NTRK2, TRKB
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

SH3K1_MOUSE
NC score	0.055124 (rank : 817)	θ value	5.27518 (rank : 844)
Query Neighborhood Hits	997	Target Neighborhood Hits	332	Shared Neighborhood Hits	86
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

NTRK2_MOUSE
NC score	0.055010 (rank : 818)	θ value	θ > 10 (rank : 1196)
Query Neighborhood Hits	997	Target Neighborhood Hits	1088	Shared Neighborhood Hits	79
SwissProt Accessions	P15209, Q3TUF9, Q80WU0, Q91XJ9	Gene names	Ntrk2, Trkb
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B).

ENAH_HUMAN
NC score	0.054985 (rank : 819)	θ value	θ > 10 (rank : 1081)
Query Neighborhood Hits	997	Target Neighborhood Hits	784	Shared Neighborhood Hits	169
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

WNK1_HUMAN
NC score	0.054893 (rank : 820)	θ value	1.81305 (rank : 653)
Query Neighborhood Hits	997	Target Neighborhood Hits	1158	Shared Neighborhood Hits	189
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

AN13D_HUMAN
NC score	0.054799 (rank : 821)	θ value	θ > 10 (rank : 1012)
Query Neighborhood Hits	997	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZTN6, Q6ZVD0, Q86SU1	Gene names	ANKRD13D
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13D.

COBA2_MOUSE
NC score	0.054772 (rank : 822)	θ value	2.36792 (rank : 662)
Query Neighborhood Hits	997	Target Neighborhood Hits	501	Shared Neighborhood Hits	171
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

TACC2_MOUSE
NC score	0.054766 (rank : 823)	θ value	5.27518 (rank : 847)
Query Neighborhood Hits	997	Target Neighborhood Hits	774	Shared Neighborhood Hits	134
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

NRX2B_HUMAN
NC score	0.054672 (rank : 824)	θ value	1.81305 (rank : 632)
Query Neighborhood Hits	997	Target Neighborhood Hits	481	Shared Neighborhood Hits	188
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

ABI2_HUMAN
NC score	0.054631 (rank : 825)	θ value	θ > 10 (rank : 1000)
Query Neighborhood Hits	997	Target Neighborhood Hits	350	Shared Neighborhood Hits	132
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

REL_MOUSE
NC score	0.054536 (rank : 826)	θ value	θ > 10 (rank : 1228)
Query Neighborhood Hits	997	Target Neighborhood Hits	77	Shared Neighborhood Hits	21
SwissProt Accessions	P15307	Gene names	Rel
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

CT151_HUMAN
NC score	0.054483 (rank : 827)	θ value	θ > 10 (rank : 1070)
Query Neighborhood Hits	997	Target Neighborhood Hits	382	Shared Neighborhood Hits	93
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

M3K13_HUMAN
NC score	0.054475 (rank : 828)	θ value	θ > 10 (rank : 1156)
Query Neighborhood Hits	997	Target Neighborhood Hits	911	Shared Neighborhood Hits	88
SwissProt Accessions	O43283	Gene names	MAP3K13, LZK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase).

RIPK1_HUMAN
NC score	0.054333 (rank : 829)	θ value	θ > 10 (rank : 1232)
Query Neighborhood Hits	997	Target Neighborhood Hits	891	Shared Neighborhood Hits	84
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

ANPRB_MOUSE
NC score	0.054111 (rank : 830)	θ value	θ > 10 (rank : 1019)
Query Neighborhood Hits	997	Target Neighborhood Hits	607	Shared Neighborhood Hits	61
SwissProt Accessions	Q6VVW5, Q6VVW3, Q6VVW4, Q8CGA9	Gene names	Npr2
Domain Architecture	No domain graphic available
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

TF65_MOUSE
NC score	0.054091 (rank : 831)	θ value	θ > 10 (rank : 1293)
Query Neighborhood Hits	997	Target Neighborhood Hits	66	Shared Neighborhood Hits	27
SwissProt Accessions	Q04207, Q62025	Gene names	Rela, Nfkb3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

CO8A2_HUMAN
NC score	0.053912 (rank : 832)	θ value	3.0926 (rank : 713)
Query Neighborhood Hits	997	Target Neighborhood Hits	299	Shared Neighborhood Hits	131
SwissProt Accessions	P25067, Q8TEJ5	Gene names	COL8A2
Domain Architecture
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

ZAN_MOUSE
NC score	0.053893 (rank : 833)	θ value	θ > 10 (rank : 1334)
Query Neighborhood Hits	997	Target Neighborhood Hits	808	Shared Neighborhood Hits	84
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

CD2AP_MOUSE
NC score	0.053735 (rank : 834)	θ value	4.03905 (rank : 761)
Query Neighborhood Hits	997	Target Neighborhood Hits	336	Shared Neighborhood Hits	98
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

NUMBL_HUMAN
NC score	0.053719 (rank : 835)	θ value	θ > 10 (rank : 1199)
Query Neighborhood Hits	997	Target Neighborhood Hits	394	Shared Neighborhood Hits	134
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

CO2A1_HUMAN
NC score	0.053703 (rank : 836)	θ value	θ > 10 (rank : 1061)
Query Neighborhood Hits	997	Target Neighborhood Hits	486	Shared Neighborhood Hits	177
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

MOS_HUMAN
NC score	0.053589 (rank : 837)	θ value	θ > 10 (rank : 1181)
Query Neighborhood Hits	997	Target Neighborhood Hits	829	Shared Neighborhood Hits	77
SwissProt Accessions	P00540	Gene names	MOS
Domain Architecture
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

NFAC1_HUMAN
NC score	0.053537 (rank : 838)	θ value	0.0961366 (rank : 413)
Query Neighborhood Hits	997	Target Neighborhood Hits	312	Shared Neighborhood Hits	131
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

CNTRB_MOUSE
NC score	0.053460 (rank : 839)	θ value	0.000786445 (rank : 287)
Query Neighborhood Hits	997	Target Neighborhood Hits	1029	Shared Neighborhood Hits	130
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

JAK1_HUMAN
NC score	0.053419 (rank : 840)	θ value	θ > 10 (rank : 1132)
Query Neighborhood Hits	997	Target Neighborhood Hits	858	Shared Neighborhood Hits	77
SwissProt Accessions	P23458	Gene names	JAK1, JAK1A
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

MUSK_HUMAN
NC score	0.053404 (rank : 841)	θ value	θ > 10 (rank : 1188)
Query Neighborhood Hits	997	Target Neighborhood Hits	1074	Shared Neighborhood Hits	77
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

PDCD7_HUMAN
NC score	0.053354 (rank : 842)	θ value	θ > 10 (rank : 1203)
Query Neighborhood Hits	997	Target Neighborhood Hits	255	Shared Neighborhood Hits	70
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

COAA1_HUMAN
NC score	0.053331 (rank : 843)	θ value	θ > 10 (rank : 1064)
Query Neighborhood Hits	997	Target Neighborhood Hits	316	Shared Neighborhood Hits	134
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

TESK2_HUMAN
NC score	0.053312 (rank : 844)	θ value	θ > 10 (rank : 1290)
Query Neighborhood Hits	997	Target Neighborhood Hits	851	Shared Neighborhood Hits	89
SwissProt Accessions	Q96S53, Q8N520, Q9Y3Q6	Gene names	TESK2
Domain Architecture
Description	Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2).

BAZ2A_MOUSE
NC score	0.053301 (rank : 845)	θ value	1.38821 (rank : 584)
Query Neighborhood Hits	997	Target Neighborhood Hits	744	Shared Neighborhood Hits	184
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

ANPRB_HUMAN
NC score	0.053236 (rank : 846)	θ value	θ > 10 (rank : 1018)
Query Neighborhood Hits	997	Target Neighborhood Hits	646	Shared Neighborhood Hits	65
SwissProt Accessions	P20594, O60871, Q9UQ50	Gene names	NPR2, ANPRB
Domain Architecture
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

JAK1_MOUSE
NC score	0.053155 (rank : 847)	θ value	θ > 10 (rank : 1133)
Query Neighborhood Hits	997	Target Neighborhood Hits	854	Shared Neighborhood Hits	77
SwissProt Accessions	P52332, Q62126	Gene names	Jak1
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

CO2A1_MOUSE
NC score	0.053144 (rank : 848)	θ value	θ > 10 (rank : 1062)
Query Neighborhood Hits	997	Target Neighborhood Hits	483	Shared Neighborhood Hits	170
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

SMOO_HUMAN
NC score	0.053122 (rank : 849)	θ value	θ > 10 (rank : 1266)
Query Neighborhood Hits	997	Target Neighborhood Hits	391	Shared Neighborhood Hits	141
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

CO4A1_HUMAN
NC score	0.053099 (rank : 850)	θ value	4.03905 (rank : 768)
Query Neighborhood Hits	997	Target Neighborhood Hits	425	Shared Neighborhood Hits	163
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

PRCC_HUMAN
NC score	0.053067 (rank : 851)	θ value	θ > 10 (rank : 1210)
Query Neighborhood Hits	997	Target Neighborhood Hits	109	Shared Neighborhood Hits	57
SwissProt Accessions	Q92733, O00665, O00724	Gene names	PRCC, TPRC
Domain Architecture	No domain graphic available
Description	Proline-rich protein PRCC (Papillary renal cell carcinoma translocation-associated gene protein).

IRS2_HUMAN
NC score	0.053000 (rank : 852)	θ value	θ > 10 (rank : 1128)
Query Neighborhood Hits	997	Target Neighborhood Hits	262	Shared Neighborhood Hits	119
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

GON4L_MOUSE
NC score	0.052994 (rank : 853)	θ value	0.0736092 (rank : 403)
Query Neighborhood Hits	997	Target Neighborhood Hits	455	Shared Neighborhood Hits	107
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

SETD2_HUMAN
NC score	0.052953 (rank : 854)	θ value	θ > 10 (rank : 1258)
Query Neighborhood Hits	997	Target Neighborhood Hits	412	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

APXL_HUMAN
NC score	0.052951 (rank : 855)	θ value	4.03905 (rank : 756)
Query Neighborhood Hits	997	Target Neighborhood Hits	553	Shared Neighborhood Hits	141
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

KSR1_HUMAN
NC score	0.052946 (rank : 856)	θ value	θ > 10 (rank : 1139)
Query Neighborhood Hits	997	Target Neighborhood Hits	867	Shared Neighborhood Hits	91
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

SPRR3_MOUSE
NC score	0.052899 (rank : 857)	θ value	4.03905 (rank : 798)
Query Neighborhood Hits	997	Target Neighborhood Hits	106	Shared Neighborhood Hits	45
SwissProt Accessions	O09116	Gene names	Sprr3
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta).

MAP1B_HUMAN
NC score	0.052860 (rank : 858)	θ value	θ > 10 (rank : 1162)
Query Neighborhood Hits	997	Target Neighborhood Hits	903	Shared Neighborhood Hits	135
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

GUC2E_MOUSE
NC score	0.052783 (rank : 859)	θ value	θ > 10 (rank : 1110)
Query Neighborhood Hits	997	Target Neighborhood Hits	692	Shared Neighborhood Hits	66
SwissProt Accessions	P52785	Gene names	Gucy2e, Guc2e
Domain Architecture
Description	Guanylyl cyclase GC-E precursor (EC 4.6.1.2) (Guanylate cyclase 2E).

MUSK_MOUSE
NC score	0.052718 (rank : 860)	θ value	θ > 10 (rank : 1189)
Query Neighborhood Hits	997	Target Neighborhood Hits	1057	Shared Neighborhood Hits	76
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

MUCDL_MOUSE
NC score	0.052550 (rank : 861)	θ value	6.88961 (rank : 896)
Query Neighborhood Hits	997	Target Neighborhood Hits	461	Shared Neighborhood Hits	132
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

RBM12_MOUSE
NC score	0.052549 (rank : 862)	θ value	θ > 10 (rank : 1224)
Query Neighborhood Hits	997	Target Neighborhood Hits	313	Shared Neighborhood Hits	122
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

SEPT9_HUMAN
NC score	0.052484 (rank : 863)	θ value	0.0193708 (rank : 357)
Query Neighborhood Hits	997	Target Neighborhood Hits	706	Shared Neighborhood Hits	199
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

ARFG3_MOUSE
NC score	0.052429 (rank : 864)	θ value	θ > 10 (rank : 1026)
Query Neighborhood Hits	997	Target Neighborhood Hits	80	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

KSR2_HUMAN
NC score	0.052392 (rank : 865)	θ value	θ > 10 (rank : 1141)
Query Neighborhood Hits	997	Target Neighborhood Hits	920	Shared Neighborhood Hits	119
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

KIT_HUMAN
NC score	0.052307 (rank : 866)	θ value	θ > 10 (rank : 1137)
Query Neighborhood Hits	997	Target Neighborhood Hits	953	Shared Neighborhood Hits	76
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

ANPRA_MOUSE
NC score	0.052265 (rank : 867)	θ value	θ > 10 (rank : 1017)
Query Neighborhood Hits	997	Target Neighborhood Hits	600	Shared Neighborhood Hits	64
SwissProt Accessions	P18293	Gene names	Npr1, Npra
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

REL_HUMAN
NC score	0.052257 (rank : 868)	θ value	θ > 10 (rank : 1227)
Query Neighborhood Hits	997	Target Neighborhood Hits	31	Shared Neighborhood Hits	9
SwissProt Accessions	Q04864, Q2PNZ7, Q6LDY0	Gene names	REL
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

CO4A3_HUMAN
NC score	0.052245 (rank : 869)	θ value	8.99809 (rank : 934)
Query Neighborhood Hits	997	Target Neighborhood Hits	421	Shared Neighborhood Hits	149
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

STAM1_MOUSE
NC score	0.052221 (rank : 870)	θ value	0.365318 (rank : 489)
Query Neighborhood Hits	997	Target Neighborhood Hits	273	Shared Neighborhood Hits	71
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

CO1A2_HUMAN
NC score	0.052218 (rank : 871)	θ value	4.03905 (rank : 767)
Query Neighborhood Hits	997	Target Neighborhood Hits	329	Shared Neighborhood Hits	130
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

TACC2_HUMAN
NC score	0.052199 (rank : 872)	θ value	3.0926 (rank : 744)
Query Neighborhood Hits	997	Target Neighborhood Hits	856	Shared Neighborhood Hits	152
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

RIPK1_MOUSE
NC score	0.052147 (rank : 873)	θ value	θ > 10 (rank : 1233)
Query Neighborhood Hits	997	Target Neighborhood Hits	874	Shared Neighborhood Hits	85
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

AMOT_HUMAN
NC score	0.052106 (rank : 874)	θ value	θ > 10 (rank : 1010)
Query Neighborhood Hits	997	Target Neighborhood Hits	712	Shared Neighborhood Hits	137
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

JAK2_HUMAN
NC score	0.052092 (rank : 875)	θ value	θ > 10 (rank : 1134)
Query Neighborhood Hits	997	Target Neighborhood Hits	847	Shared Neighborhood Hits	77
SwissProt Accessions	O60674, O14636, O75297	Gene names	JAK2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

EMID2_HUMAN
NC score	0.052084 (rank : 876)	θ value	θ > 10 (rank : 1080)
Query Neighborhood Hits	997	Target Neighborhood Hits	226	Shared Neighborhood Hits	106
SwissProt Accessions	Q96A83	Gene names	EMID2, COL26A1, EMU2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

CO9A1_MOUSE
NC score	0.052057 (rank : 877)	θ value	θ > 10 (rank : 1063)
Query Neighborhood Hits	997	Target Neighborhood Hits	477	Shared Neighborhood Hits	160
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

LR37A_HUMAN
NC score	0.051994 (rank : 878)	θ value	1.81305 (rank : 624)
Query Neighborhood Hits	997	Target Neighborhood Hits	720	Shared Neighborhood Hits	167
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

KIT_MOUSE
NC score	0.051975 (rank : 879)	θ value	θ > 10 (rank : 1138)
Query Neighborhood Hits	997	Target Neighborhood Hits	949	Shared Neighborhood Hits	79
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

NFH_HUMAN
NC score	0.051877 (rank : 880)	θ value	6.88961 (rank : 899)
Query Neighborhood Hits	997	Target Neighborhood Hits	1242	Shared Neighborhood Hits	189
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CO002_HUMAN
NC score	0.051847 (rank : 881)	θ value	θ > 10 (rank : 1059)
Query Neighborhood Hits	997	Target Neighborhood Hits	387	Shared Neighborhood Hits	128
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

CD2AP_HUMAN
NC score	0.051828 (rank : 882)	θ value	1.81305 (rank : 612)
Query Neighborhood Hits	997	Target Neighborhood Hits	315	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

AMPH_HUMAN
NC score	0.051811 (rank : 883)	θ value	θ > 10 (rank : 1011)
Query Neighborhood Hits	997	Target Neighborhood Hits	455	Shared Neighborhood Hits	122
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

ACINU_MOUSE
NC score	0.051723 (rank : 884)	θ value	θ > 10 (rank : 1005)
Query Neighborhood Hits	997	Target Neighborhood Hits	712	Shared Neighborhood Hits	124
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ARFG1_MOUSE
NC score	0.051665 (rank : 885)	θ value	θ > 10 (rank : 1024)
Query Neighborhood Hits	997	Target Neighborhood Hits	51	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EPJ9, Q3TI52, Q8BMM6, Q8BMQ7	Gene names	Arfgap1, Arf1gap
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

SRBP1_MOUSE
NC score	0.051522 (rank : 886)	θ value	0.21417 (rank : 460)
Query Neighborhood Hits	997	Target Neighborhood Hits	384	Shared Neighborhood Hits	128
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SPEG_MOUSE
NC score	0.051513 (rank : 887)	θ value	0.125558 (rank : 428)
Query Neighborhood Hits	997	Target Neighborhood Hits	1959	Shared Neighborhood Hits	362
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ARFG3_HUMAN
NC score	0.051511 (rank : 888)	θ value	θ > 10 (rank : 1025)
Query Neighborhood Hits	997	Target Neighborhood Hits	56	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

PYGO2_HUMAN
NC score	0.051510 (rank : 889)	θ value	θ > 10 (rank : 1221)
Query Neighborhood Hits	997	Target Neighborhood Hits	189	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

PTN23_MOUSE
NC score	0.051492 (rank : 890)	θ value	θ > 10 (rank : 1220)
Query Neighborhood Hits	997	Target Neighborhood Hits	726	Shared Neighborhood Hits	232
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

TYK2_MOUSE
NC score	0.051438 (rank : 891)	θ value	θ > 10 (rank : 1316)
Query Neighborhood Hits	997	Target Neighborhood Hits	850	Shared Neighborhood Hits	83
SwissProt Accessions	Q9R117, O88431, Q8VE41	Gene names	Tyk2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

TCGAP_MOUSE
NC score	0.051401 (rank : 892)	θ value	8.99809 (rank : 988)
Query Neighborhood Hits	997	Target Neighborhood Hits	409	Shared Neighborhood Hits	154
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

ZDHC5_MOUSE
NC score	0.051376 (rank : 893)	θ value	0.0431538 (rank : 390)
Query Neighborhood Hits	997	Target Neighborhood Hits	113	Shared Neighborhood Hits	34
SwissProt Accessions	Q8VDZ4, Q69ZB5, Q8R2X7	Gene names	Zdhhc5, Kiaa1748
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC5 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 5) (DHHC-5).

TOPK_HUMAN
NC score	0.051338 (rank : 894)	θ value	θ > 10 (rank : 1303)
Query Neighborhood Hits	997	Target Neighborhood Hits	605	Shared Neighborhood Hits	60
SwissProt Accessions	Q96KB5, Q9NPD9, Q9NYL7, Q9NZK6	Gene names	PBK, TOPK
Domain Architecture	No domain graphic available
Description	T-lymphokine-activated killer cell-originated protein kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase) (Spermatogenesis-related protein kinase) (SPK) (MAPKK-like protein kinase) (Nori-3).

BMPR2_MOUSE
NC score	0.051268 (rank : 895)	θ value	θ > 10 (rank : 1038)
Query Neighborhood Hits	997	Target Neighborhood Hits	738	Shared Neighborhood Hits	75
SwissProt Accessions	O35607	Gene names	Bmpr2
Domain Architecture
Description	Bone morphogenetic protein receptor type-2 precursor (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II) (BRK-3).

CENA2_MOUSE
NC score	0.051199 (rank : 896)	θ value	θ > 10 (rank : 1050)
Query Neighborhood Hits	997	Target Neighborhood Hits	68	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

JAK3_HUMAN
NC score	0.051158 (rank : 897)	θ value	θ > 10 (rank : 1136)
Query Neighborhood Hits	997	Target Neighborhood Hits	827	Shared Neighborhood Hits	77
SwissProt Accessions	P52333, Q13259, Q13260, Q13611, Q9Y6S2	Gene names	JAK3
Domain Architecture
Description	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK).

JAK2_MOUSE
NC score	0.051123 (rank : 898)	θ value	θ > 10 (rank : 1135)
Query Neighborhood Hits	997	Target Neighborhood Hits	839	Shared Neighborhood Hits	77
SwissProt Accessions	Q62120, Q62124	Gene names	Jak2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

CG1_HUMAN
NC score	0.051121 (rank : 899)	θ value	θ > 10 (rank : 1052)
Query Neighborhood Hits	997	Target Neighborhood Hits	222	Shared Neighborhood Hits	89
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

BMPR2_HUMAN
NC score	0.051114 (rank : 900)	θ value	θ > 10 (rank : 1037)
Query Neighborhood Hits	997	Target Neighborhood Hits	736	Shared Neighborhood Hits	71
SwissProt Accessions	Q13873, Q16569	Gene names	BMPR2, PPH1
Domain Architecture
Description	Bone morphogenetic protein receptor type-2 precursor (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II).

CENA2_HUMAN
NC score	0.051094 (rank : 901)	θ value	θ > 10 (rank : 1049)
Query Neighborhood Hits	997	Target Neighborhood Hits	83	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

STAM1_HUMAN
NC score	0.051080 (rank : 902)	θ value	0.47712 (rank : 509)
Query Neighborhood Hits	997	Target Neighborhood Hits	271	Shared Neighborhood Hits	68
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

TESK1_MOUSE
NC score	0.051047 (rank : 903)	θ value	θ > 10 (rank : 1289)
Query Neighborhood Hits	997	Target Neighborhood Hits	862	Shared Neighborhood Hits	106
SwissProt Accessions	O70146, O70147	Gene names	Tesk1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

TYK2_HUMAN
NC score	0.051046 (rank : 904)	θ value	θ > 10 (rank : 1315)
Query Neighborhood Hits	997	Target Neighborhood Hits	841	Shared Neighborhood Hits	78
SwissProt Accessions	P29597, Q6QB10, Q96CH0	Gene names	TYK2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

VCXC_HUMAN
NC score	0.051044 (rank : 905)	θ value	θ > 10 (rank : 1323)
Query Neighborhood Hits	997	Target Neighborhood Hits	139	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

LTBP2_MOUSE
NC score	0.051043 (rank : 906)	θ value	θ > 10 (rank : 1148)
Query Neighborhood Hits	997	Target Neighborhood Hits	617	Shared Neighborhood Hits	88
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

TESK2_MOUSE
NC score	0.051031 (rank : 907)	θ value	θ > 10 (rank : 1291)
Query Neighborhood Hits	997	Target Neighborhood Hits	833	Shared Neighborhood Hits	78
SwissProt Accessions	Q8VCT9	Gene names	Tesk2
Domain Architecture
Description	Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2).

CO9A1_HUMAN
NC score	0.051025 (rank : 908)	θ value	1.81305 (rank : 616)
Query Neighborhood Hits	997	Target Neighborhood Hits	420	Shared Neighborhood Hits	141
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

RELB_HUMAN
NC score	0.050999 (rank : 909)	θ value	θ > 10 (rank : 1225)
Query Neighborhood Hits	997	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	Q01201, Q6GTX7, Q9UEI7	Gene names	RELB
Domain Architecture
Description	Transcription factor RelB (I-Rel).

JADE2_MOUSE
NC score	0.050951 (rank : 910)	θ value	0.00869519 (rank : 335)
Query Neighborhood Hits	997	Target Neighborhood Hits	560	Shared Neighborhood Hits	180
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

WNK4_MOUSE
NC score	0.050927 (rank : 911)	θ value	θ > 10 (rank : 1331)
Query Neighborhood Hits	997	Target Neighborhood Hits	961	Shared Neighborhood Hits	159
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

LPP_HUMAN
NC score	0.050888 (rank : 912)	θ value	1.06291 (rank : 565)
Query Neighborhood Hits	997	Target Neighborhood Hits	775	Shared Neighborhood Hits	221
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

NSD1_MOUSE
NC score	0.050871 (rank : 913)	θ value	θ > 10 (rank : 1193)
Query Neighborhood Hits	997	Target Neighborhood Hits	472	Shared Neighborhood Hits	110
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

ZIM10_MOUSE
NC score	0.050833 (rank : 914)	θ value	θ > 10 (rank : 1338)
Query Neighborhood Hits	997	Target Neighborhood Hits	430	Shared Neighborhood Hits	172
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

FGFR4_MOUSE
NC score	0.050826 (rank : 915)	θ value	θ > 10 (rank : 1099)
Query Neighborhood Hits	997	Target Neighborhood Hits	1026	Shared Neighborhood Hits	83
SwissProt Accessions	Q03142, Q5J7D9, Q8C3V5, Q8CIB8	Gene names	Fgfr4, Fgfr-4, Mpk-11
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) (CD334 antigen).

TESK1_HUMAN
NC score	0.050766 (rank : 916)	θ value	θ > 10 (rank : 1288)
Query Neighborhood Hits	997	Target Neighborhood Hits	864	Shared Neighborhood Hits	105
SwissProt Accessions	Q15569	Gene names	TESK1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

RELB_MOUSE
NC score	0.050755 (rank : 917)	θ value	θ > 10 (rank : 1226)
Query Neighborhood Hits	997	Target Neighborhood Hits	21	Shared Neighborhood Hits	6
SwissProt Accessions	Q04863	Gene names	Relb
Domain Architecture
Description	Transcription factor RelB.

CO9A3_HUMAN
NC score	0.050632 (rank : 918)	θ value	1.06291 (rank : 556)
Query Neighborhood Hits	997	Target Neighborhood Hits	361	Shared Neighborhood Hits	130
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

RTN4_HUMAN
NC score	0.050609 (rank : 919)	θ value	θ > 10 (rank : 1248)
Query Neighborhood Hits	997	Target Neighborhood Hits	357	Shared Neighborhood Hits	119
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

STYK1_HUMAN
NC score	0.050573 (rank : 920)	θ value	θ > 10 (rank : 1278)
Query Neighborhood Hits	997	Target Neighborhood Hits	786	Shared Neighborhood Hits	75
SwissProt Accessions	Q6J9G0, Q9BXY2, Q9NSH1	Gene names	STYK1, NOK
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (Protein PK-unique).

SETB1_MOUSE
NC score	0.050500 (rank : 921)	θ value	θ > 10 (rank : 1257)
Query Neighborhood Hits	997	Target Neighborhood Hits	150	Shared Neighborhood Hits	44
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

LIPB2_HUMAN
NC score	0.050455 (rank : 922)	θ value	3.0926 (rank : 724)
Query Neighborhood Hits	997	Target Neighborhood Hits	599	Shared Neighborhood Hits	68
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

ARFG1_HUMAN
NC score	0.050349 (rank : 923)	θ value	θ > 10 (rank : 1023)
Query Neighborhood Hits	997	Target Neighborhood Hits	60	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N6T3, Q96KC4, Q96T02, Q9NSU3, Q9NVF6, Q9UIL0	Gene names	ARFGAP1, ARF1GAP
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

WNK1_MOUSE
NC score	0.050296 (rank : 924)	θ value	θ > 10 (rank : 1329)
Query Neighborhood Hits	997	Target Neighborhood Hits	1179	Shared Neighborhood Hits	174
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

CASL_HUMAN
NC score	0.050277 (rank : 925)	θ value	1.38821 (rank : 587)
Query Neighborhood Hits	997	Target Neighborhood Hits	259	Shared Neighborhood Hits	74
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

ANPRA_HUMAN
NC score	0.050264 (rank : 926)	θ value	θ > 10 (rank : 1016)
Query Neighborhood Hits	997	Target Neighborhood Hits	612	Shared Neighborhood Hits	63
SwissProt Accessions	P16066, Q6P4Q3	Gene names	NPR1, ANPRA
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

PGFRB_HUMAN
NC score	0.050216 (rank : 927)	θ value	θ > 10 (rank : 1205)
Query Neighborhood Hits	997	Target Neighborhood Hits	962	Shared Neighborhood Hits	77
SwissProt Accessions	P09619, Q8N5L4	Gene names	PDGFRB
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

VCX1_HUMAN
NC score	0.050192 (rank : 928)	θ value	θ > 10 (rank : 1321)
Query Neighborhood Hits	997	Target Neighborhood Hits	129	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

MAP1B_MOUSE
NC score	0.050191 (rank : 929)	θ value	θ > 10 (rank : 1163)
Query Neighborhood Hits	997	Target Neighborhood Hits	977	Shared Neighborhood Hits	161
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

CO5A3_HUMAN
NC score	0.050139 (rank : 930)	θ value	6.88961 (rank : 871)
Query Neighborhood Hits	997	Target Neighborhood Hits	433	Shared Neighborhood Hits	154
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

FGFR4_HUMAN
NC score	0.050119 (rank : 931)	θ value	θ > 10 (rank : 1098)
Query Neighborhood Hits	997	Target Neighborhood Hits	1037	Shared Neighborhood Hits	83
SwissProt Accessions	P22455, O43785, Q14309	Gene names	FGFR4, JTK2, TKF
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (CD334 antigen).

GTSE1_HUMAN
NC score	0.050087 (rank : 932)	θ value	θ > 10 (rank : 1108)
Query Neighborhood Hits	997	Target Neighborhood Hits	193	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

FGFR3_HUMAN
NC score	0.050081 (rank : 933)	θ value	θ > 10 (rank : 1097)
Query Neighborhood Hits	997	Target Neighborhood Hits	1042	Shared Neighborhood Hits	80
SwissProt Accessions	P22607, Q14308, Q16294, Q16608	Gene names	FGFR3, JTK4
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (CD333 antigen).

PGFRB_MOUSE
NC score	0.050034 (rank : 934)	θ value	θ > 10 (rank : 1206)
Query Neighborhood Hits	997	Target Neighborhood Hits	960	Shared Neighborhood Hits	77
SwissProt Accessions	P05622	Gene names	Pdgfrb, Pdgfr
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

IF4G1_HUMAN
NC score	0.050033 (rank : 935)	θ value	θ > 10 (rank : 1116)
Query Neighborhood Hits	997	Target Neighborhood Hits	347	Shared Neighborhood Hits	116
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

KSR1_MOUSE
NC score	0.050011 (rank : 936)	θ value	θ > 10 (rank : 1140)
Query Neighborhood Hits	997	Target Neighborhood Hits	870	Shared Neighborhood Hits	84
SwissProt Accessions	Q61097, Q61648, Q78DX8	Gene names	Ksr1, Ksr
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein).

LCE1B_HUMAN
NC score	0.050003 (rank : 937)	θ value	θ > 10 (rank : 1145)
Query Neighborhood Hits	997	Target Neighborhood Hits	58	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

JIP2_HUMAN
NC score	0.049937 (rank : 938)	θ value	5.27518 (rank : 826)
Query Neighborhood Hits	997	Target Neighborhood Hits	288	Shared Neighborhood Hits	112
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

CCD96_HUMAN
NC score	0.049833 (rank : 939)	θ value	0.00390308 (rank : 316)
Query Neighborhood Hits	997	Target Neighborhood Hits	595	Shared Neighborhood Hits	95
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

ZN598_HUMAN
NC score	0.049813 (rank : 940)	θ value	6.88961 (rank : 919)
Query Neighborhood Hits	997	Target Neighborhood Hits	339	Shared Neighborhood Hits	95
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

HCLS1_HUMAN
NC score	0.049517 (rank : 941)	θ value	0.47712 (rank : 500)
Query Neighborhood Hits	997	Target Neighborhood Hits	358	Shared Neighborhood Hits	127
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

BTBDC_HUMAN
NC score	0.049076 (rank : 942)	θ value	0.365318 (rank : 479)
Query Neighborhood Hits	997	Target Neighborhood Hits	248	Shared Neighborhood Hits	56
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

LTB1L_HUMAN
NC score	0.049051 (rank : 943)	θ value	1.06291 (rank : 566)
Query Neighborhood Hits	997	Target Neighborhood Hits	553	Shared Neighborhood Hits	78
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

GON4L_HUMAN
NC score	0.048997 (rank : 944)	θ value	0.279714 (rank : 466)
Query Neighborhood Hits	997	Target Neighborhood Hits	555	Shared Neighborhood Hits	110
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

ZN750_MOUSE
NC score	0.048919 (rank : 945)	θ value	1.38821 (rank : 610)
Query Neighborhood Hits	997	Target Neighborhood Hits	346	Shared Neighborhood Hits	101
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

EP400_HUMAN
NC score	0.048810 (rank : 946)	θ value	6.88961 (rank : 884)
Query Neighborhood Hits	997	Target Neighborhood Hits	556	Shared Neighborhood Hits	188
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

EP400_MOUSE
NC score	0.048786 (rank : 947)	θ value	1.38821 (rank : 595)
Query Neighborhood Hits	997	Target Neighborhood Hits	592	Shared Neighborhood Hits	178
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

CO8A1_HUMAN
NC score	0.048769 (rank : 948)	θ value	8.99809 (rank : 935)
Query Neighborhood Hits	997	Target Neighborhood Hits	288	Shared Neighborhood Hits	121
SwissProt Accessions	P27658, Q96D07	Gene names	COL8A1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor (Endothelial collagen).

TS13_MOUSE
NC score	0.048677 (rank : 949)	θ value	1.06291 (rank : 581)
Query Neighborhood Hits	997	Target Neighborhood Hits	191	Shared Neighborhood Hits	75
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

CO8A1_MOUSE
NC score	0.048261 (rank : 950)	θ value	8.99809 (rank : 936)
Query Neighborhood Hits	997	Target Neighborhood Hits	251	Shared Neighborhood Hits	108
SwissProt Accessions	Q00780, Q9D2V4	Gene names	Col8a1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor.

3BP1_MOUSE
NC score	0.048243 (rank : 951)	θ value	8.99809 (rank : 920)
Query Neighborhood Hits	997	Target Neighborhood Hits	238	Shared Neighborhood Hits	104
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

DAB2_MOUSE
NC score	0.048239 (rank : 952)	θ value	0.813845 (rank : 538)
Query Neighborhood Hits	997	Target Neighborhood Hits	163	Shared Neighborhood Hits	59
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

PER3_HUMAN
NC score	0.048195 (rank : 953)	θ value	5.27518 (rank : 836)
Query Neighborhood Hits	997	Target Neighborhood Hits	479	Shared Neighborhood Hits	150
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

MARK2_HUMAN
NC score	0.048183 (rank : 954)	θ value	9.29e-05 (rank : 264)
Query Neighborhood Hits	997	Target Neighborhood Hits	1056	Shared Neighborhood Hits	139
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

LTB1S_HUMAN
NC score	0.047843 (rank : 955)	θ value	1.06291 (rank : 567)
Query Neighborhood Hits	997	Target Neighborhood Hits	502	Shared Neighborhood Hits	65
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

ULK1_HUMAN
NC score	0.047270 (rank : 956)	θ value	1.81305 (rank : 647)
Query Neighborhood Hits	997	Target Neighborhood Hits	1121	Shared Neighborhood Hits	208
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

CONA1_HUMAN
NC score	0.047268 (rank : 957)	θ value	8.99809 (rank : 937)
Query Neighborhood Hits	997	Target Neighborhood Hits	281	Shared Neighborhood Hits	106
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

TXLNB_HUMAN
NC score	0.047171 (rank : 958)	θ value	0.163984 (rank : 444)
Query Neighborhood Hits	997	Target Neighborhood Hits	912	Shared Neighborhood Hits	154
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

COFA1_MOUSE
NC score	0.046994 (rank : 959)	θ value	5.27518 (rank : 814)
Query Neighborhood Hits	997	Target Neighborhood Hits	305	Shared Neighborhood Hits	125
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

TPO_MOUSE
NC score	0.046739 (rank : 960)	θ value	0.47712 (rank : 510)
Query Neighborhood Hits	997	Target Neighborhood Hits	258	Shared Neighborhood Hits	91
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

SPEG_HUMAN
NC score	0.046709 (rank : 961)	θ value	8.99809 (rank : 980)
Query Neighborhood Hits	997	Target Neighborhood Hits	1762	Shared Neighborhood Hits	318
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

RAI1_HUMAN
NC score	0.046515 (rank : 962)	θ value	1.06291 (rank : 574)
Query Neighborhood Hits	997	Target Neighborhood Hits	360	Shared Neighborhood Hits	118
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

CO4A6_HUMAN
NC score	0.046357 (rank : 963)	θ value	0.62314 (rank : 516)
Query Neighborhood Hits	997	Target Neighborhood Hits	318	Shared Neighborhood Hits	113
SwissProt Accessions	Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4	Gene names	COL4A6
Domain Architecture
Description	Collagen alpha-6(IV) chain precursor.

WDR46_MOUSE
NC score	0.046182 (rank : 964)	θ value	0.0193708 (rank : 358)
Query Neighborhood Hits	997	Target Neighborhood Hits	243	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

CONA1_MOUSE
NC score	0.045788 (rank : 965)	θ value	6.88961 (rank : 874)
Query Neighborhood Hits	997	Target Neighborhood Hits	254	Shared Neighborhood Hits	106
SwissProt Accessions	Q8K4G2, Q5SUQ0	Gene names	Col23a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

CNKR2_MOUSE
NC score	0.045738 (rank : 966)	θ value	4.03905 (rank : 765)
Query Neighborhood Hits	997	Target Neighborhood Hits	197	Shared Neighborhood Hits	36
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.045700 (rank : 967)	θ value	4.03905 (rank : 764)
Query Neighborhood Hits	997	Target Neighborhood Hits	197	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

NRX2A_HUMAN
NC score	0.045504 (rank : 968)	θ value	1.81305 (rank : 631)
Query Neighborhood Hits	997	Target Neighborhood Hits	614	Shared Neighborhood Hits	201
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

MEF2B_MOUSE
NC score	0.045418 (rank : 969)	θ value	0.0330416 (rank : 375)
Query Neighborhood Hits	997	Target Neighborhood Hits	218	Shared Neighborhood Hits	97
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

LRSM1_HUMAN
NC score	0.045352 (rank : 970)	θ value	0.813845 (rank : 544)
Query Neighborhood Hits	997	Target Neighborhood Hits	1078	Shared Neighborhood Hits	92
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

SYN2_MOUSE
NC score	0.045327 (rank : 971)	θ value	6.88961 (rank : 906)
Query Neighborhood Hits	997	Target Neighborhood Hits	183	Shared Neighborhood Hits	94
SwissProt Accessions	Q64332, Q6NZR0, Q9QWV7	Gene names	Syn2
Domain Architecture	No domain graphic available
Description	Synapsin-2 (Synapsin II).

HCN2_HUMAN
NC score	0.045226 (rank : 972)	θ value	5.27518 (rank : 824)
Query Neighborhood Hits	997	Target Neighborhood Hits	369	Shared Neighborhood Hits	175
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

EDA_MOUSE
NC score	0.045163 (rank : 973)	θ value	2.36792 (rank : 671)
Query Neighborhood Hits	997	Target Neighborhood Hits	141	Shared Neighborhood Hits	72
SwissProt Accessions	O54693, O35705, Q9QWJ8, Q9QZ01, Q9QZ02	Gene names	Eda, Ed1, Ta
Domain Architecture
Description	Ectodysplasin-A (EDA protein homolog) (Tabby protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

3BP2_HUMAN
NC score	0.044943 (rank : 974)	θ value	4.03905 (rank : 751)
Query Neighborhood Hits	997	Target Neighborhood Hits	296	Shared Neighborhood Hits	115
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

PAK4_MOUSE
NC score	0.044697 (rank : 975)	θ value	2.36792 (rank : 685)
Query Neighborhood Hits	997	Target Neighborhood Hits	1098	Shared Neighborhood Hits	198
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

SF3B4_HUMAN
NC score	0.044650 (rank : 976)	θ value	1.81305 (rank : 638)
Query Neighborhood Hits	997	Target Neighborhood Hits	445	Shared Neighborhood Hits	127
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

EDA_HUMAN
NC score	0.044580 (rank : 977)	θ value	2.36792 (rank : 670)
Query Neighborhood Hits	997	Target Neighborhood Hits	134	Shared Neighborhood Hits	73
SwissProt Accessions	Q92838, O75910, Q5JUM7, Q9UP77, Q9Y6L0, Q9Y6L1, Q9Y6L2, Q9Y6L3, Q9Y6L4	Gene names	EDA, ED1
Domain Architecture
Description	Ectodysplasin-A (Ectodermal dysplasia protein) (EDA protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

PRAX_MOUSE
NC score	0.044269 (rank : 978)	θ value	1.06291 (rank : 573)
Query Neighborhood Hits	997	Target Neighborhood Hits	199	Shared Neighborhood Hits	76
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

TITIN_HUMAN
NC score	0.044042 (rank : 979)	θ value	8.99809 (rank : 990)
Query Neighborhood Hits	997	Target Neighborhood Hits	2923	Shared Neighborhood Hits	353
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

LRSM1_MOUSE
NC score	0.044016 (rank : 980)	θ value	0.0252991 (rank : 363)
Query Neighborhood Hits	997	Target Neighborhood Hits	874	Shared Neighborhood Hits	65
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

PHLB1_MOUSE
NC score	0.043906 (rank : 981)	θ value	6.88961 (rank : 902)
Query Neighborhood Hits	997	Target Neighborhood Hits	678	Shared Neighborhood Hits	134
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

CT055_MOUSE
NC score	0.043857 (rank : 982)	θ value	3.0926 (rank : 717)
Query Neighborhood Hits	997	Target Neighborhood Hits	52	Shared Neighborhood Hits	33
SwissProt Accessions	Q8R184, Q8BQE5, Q8K024, Q8VEM7, Q9CU80	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf55 homolog.

ZDHC5_HUMAN
NC score	0.043651 (rank : 983)	θ value	0.813845 (rank : 550)
Query Neighborhood Hits	997	Target Neighborhood Hits	106	Shared Neighborhood Hits	28
SwissProt Accessions	Q9C0B5, Q6ZMF0, Q8TAK8, Q9H923, Q9UFI7	Gene names	ZDHHC5, KIAA1748, ZNF375
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC5 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 5) (DHHC-5) (Zinc finger protein 375).

LTB1L_MOUSE
NC score	0.043388 (rank : 984)	θ value	1.81305 (rank : 625)
Query Neighborhood Hits	997	Target Neighborhood Hits	514	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

AAK1_HUMAN
NC score	0.043368 (rank : 985)	θ value	8.99809 (rank : 921)
Query Neighborhood Hits	997	Target Neighborhood Hits	1077	Shared Neighborhood Hits	199
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

C2TA_HUMAN
NC score	0.043191 (rank : 986)	θ value	0.0148317 (rank : 347)
Query Neighborhood Hits	997	Target Neighborhood Hits	190	Shared Neighborhood Hits	55
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

SOX13_HUMAN
NC score	0.043172 (rank : 987)	θ value	1.81305 (rank : 640)
Query Neighborhood Hits	997	Target Neighborhood Hits	464	Shared Neighborhood Hits	145
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

ZIMP7_HUMAN
NC score	0.043058 (rank : 988)	θ value	1.38821 (rank : 608)
Query Neighborhood Hits	997	Target Neighborhood Hits	290	Shared Neighborhood Hits	120
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

LTB1S_MOUSE
NC score	0.042888 (rank : 989)	θ value	1.81305 (rank : 626)
Query Neighborhood Hits	997	Target Neighborhood Hits	479	Shared Neighborhood Hits	50
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

SETBP_MOUSE
NC score	0.042751 (rank : 990)	θ value	4.03905 (rank : 793)
Query Neighborhood Hits	997	Target Neighborhood Hits	352	Shared Neighborhood Hits	111
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

LAMA5_HUMAN
NC score	0.042738 (rank : 991)	θ value	1.06291 (rank : 564)
Query Neighborhood Hits	997	Target Neighborhood Hits	976	Shared Neighborhood Hits	118
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

HRBL_HUMAN
NC score	0.042358 (rank : 992)	θ value	8.99809 (rank : 954)
Query Neighborhood Hits	997	Target Neighborhood Hits	179	Shared Neighborhood Hits	72
SwissProt Accessions	O95081, O75429, Q96AB9, Q96GL4	Gene names	HRBL, RABR
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

MYLK_MOUSE
NC score	0.042261 (rank : 993)	θ value	2.36792 (rank : 683)
Query Neighborhood Hits	997	Target Neighborhood Hits	1489	Shared Neighborhood Hits	198
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

STK10_HUMAN
NC score	0.042206 (rank : 994)	θ value	8.99809 (rank : 984)
Query Neighborhood Hits	997	Target Neighborhood Hits	1921	Shared Neighborhood Hits	195
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

MYO15_HUMAN
NC score	0.041674 (rank : 995)	θ value	0.00390308 (rank : 319)
Query Neighborhood Hits	997	Target Neighborhood Hits	671	Shared Neighborhood Hits	232
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

MARK2_MOUSE
NC score	0.041537 (rank : 996)	θ value	0.47712 (rank : 502)
Query Neighborhood Hits	997	Target Neighborhood Hits	1018	Shared Neighborhood Hits	129
SwissProt Accessions	Q05512, Q6PDR4, Q8BR95	Gene names	Mark2, Emk
Domain Architecture
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1).

JIP1_HUMAN
NC score	0.041373 (rank : 997)	θ value	8.99809 (rank : 959)
Query Neighborhood Hits	997	Target Neighborhood Hits	271	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

MBB1A_MOUSE
NC score	0.041340 (rank : 998)	θ value	0.47712 (rank : 503)
Query Neighborhood Hits	997	Target Neighborhood Hits	233	Shared Neighborhood Hits	60
SwissProt Accessions	Q7TPV4, O35851, Q80Y66, Q8R4X2, Q99KP0	Gene names	Mybbp1a, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A (Myb-binding protein of 160 kDa).

ASTL_HUMAN
NC score	0.041244 (rank : 999)	θ value	4.03905 (rank : 758)
Query Neighborhood Hits	997	Target Neighborhood Hits	252	Shared Neighborhood Hits	95
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

EPN3_MOUSE
NC score	0.041187 (rank : 1000)	θ value	4.03905 (rank : 775)
Query Neighborhood Hits	997	Target Neighborhood Hits	312	Shared Neighborhood Hits	121
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

JIP3_HUMAN
NC score	0.041159 (rank : 1001)	θ value	0.47712 (rank : 501)
Query Neighborhood Hits	997	Target Neighborhood Hits	1039	Shared Neighborhood Hits	174
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

HGS_MOUSE
NC score	0.040710 (rank : 1002)	θ value	8.99809 (rank : 953)
Query Neighborhood Hits	997	Target Neighborhood Hits	589	Shared Neighborhood Hits	123
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

AAK1_MOUSE
NC score	0.040391 (rank : 1003)	θ value	2.36792 (rank : 654)
Query Neighborhood Hits	997	Target Neighborhood Hits	1051	Shared Neighborhood Hits	175
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

SRCA_HUMAN
NC score	0.040020 (rank : 1004)	θ value	0.62314 (rank : 532)
Query Neighborhood Hits	997	Target Neighborhood Hits	380	Shared Neighborhood Hits	80
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

SNIP_MOUSE
NC score	0.039983 (rank : 1005)	θ value	3.0926 (rank : 740)
Query Neighborhood Hits	997	Target Neighborhood Hits	319	Shared Neighborhood Hits	78
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

ITSN1_HUMAN
NC score	0.039948 (rank : 1006)	θ value	6.88961 (rank : 890)
Query Neighborhood Hits	997	Target Neighborhood Hits	1757	Shared Neighborhood Hits	213
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

AMOL1_MOUSE
NC score	0.039708 (rank : 1007)	θ value	0.0148317 (rank : 346)
Query Neighborhood Hits	997	Target Neighborhood Hits	445	Shared Neighborhood Hits	65
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

CDAN1_HUMAN
NC score	0.039521 (rank : 1008)	θ value	8.99809 (rank : 932)
Query Neighborhood Hits	997	Target Neighborhood Hits	92	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IWY9, Q7Z7L5, Q969N3	Gene names	CDAN1
Domain Architecture	No domain graphic available
Description	Codanin-1.

STAM2_MOUSE
NC score	0.039400 (rank : 1009)	θ value	6.88961 (rank : 905)
Query Neighborhood Hits	997	Target Neighborhood Hits	285	Shared Neighborhood Hits	62
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

SAMD8_MOUSE
NC score	0.039351 (rank : 1010)	θ value	0.0193708 (rank : 355)
Query Neighborhood Hits	997	Target Neighborhood Hits	22	Shared Neighborhood Hits	9
SwissProt Accessions	Q9DA37	Gene names	Samd8
Domain Architecture
Description	Sphingomyelin synthase-related protein 1 (Sterile alpha motif domain- containing 8).

GRAP_HUMAN
NC score	0.039342 (rank : 1011)	θ value	6.88961 (rank : 887)
Query Neighborhood Hits	997	Target Neighborhood Hits	307	Shared Neighborhood Hits	70
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

SMCA4_HUMAN
NC score	0.039222 (rank : 1012)	θ value	1.38821 (rank : 607)
Query Neighborhood Hits	997	Target Neighborhood Hits	597	Shared Neighborhood Hits	173
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

BAZ2A_HUMAN
NC score	0.038859 (rank : 1013)	θ value	4.03905 (rank : 760)
Query Neighborhood Hits	997	Target Neighborhood Hits	780	Shared Neighborhood Hits	167
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

OBF1_HUMAN
NC score	0.038805 (rank : 1014)	θ value	6.88961 (rank : 900)
Query Neighborhood Hits	997	Target Neighborhood Hits	203	Shared Neighborhood Hits	75
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

HAIR_HUMAN
NC score	0.038733 (rank : 1015)	θ value	0.0193708 (rank : 352)
Query Neighborhood Hits	997	Target Neighborhood Hits	172	Shared Neighborhood Hits	52
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

AHI1_HUMAN
NC score	0.038665 (rank : 1016)	θ value	0.0148317 (rank : 345)
Query Neighborhood Hits	997	Target Neighborhood Hits	537	Shared Neighborhood Hits	70
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

ARHG6_MOUSE
NC score	0.038541 (rank : 1017)	θ value	1.38821 (rank : 583)
Query Neighborhood Hits	997	Target Neighborhood Hits	394	Shared Neighborhood Hits	71
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

DEN1A_MOUSE
NC score	0.038413 (rank : 1018)	θ value	0.365318 (rank : 482)
Query Neighborhood Hits	997	Target Neighborhood Hits	178	Shared Neighborhood Hits	74
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

HEMGN_MOUSE
NC score	0.038392 (rank : 1019)	θ value	0.0431538 (rank : 384)
Query Neighborhood Hits	997	Target Neighborhood Hits	81	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ERZ0, Q3TAE6, Q80YT2, Q8CF29	Gene names	Hemgn, Ndr
Domain Architecture	No domain graphic available
Description	Hemogen (Hemopoietic gene protein) (Negative differentiation regulator protein) (mNDR).

CUTL1_HUMAN
NC score	0.038325 (rank : 1020)	θ value	8.99809 (rank : 940)
Query Neighborhood Hits	997	Target Neighborhood Hits	1574	Shared Neighborhood Hits	175
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

CAMKV_HUMAN
NC score	0.038201 (rank : 1021)	θ value	0.00102713 (rank : 288)
Query Neighborhood Hits	997	Target Neighborhood Hits	1084	Shared Neighborhood Hits	166
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

SN1L1_MOUSE
NC score	0.038186 (rank : 1022)	θ value	5.27518 (rank : 845)
Query Neighborhood Hits	997	Target Neighborhood Hits	895	Shared Neighborhood Hits	93
SwissProt Accessions	Q60670	Gene names	Snf1lk, Msk
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1- like kinase).

MAST1_HUMAN
NC score	0.038001 (rank : 1023)	θ value	0.279714 (rank : 468)
Query Neighborhood Hits	997	Target Neighborhood Hits	1146	Shared Neighborhood Hits	157
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

GNAS1_HUMAN
NC score	0.037815 (rank : 1024)	θ value	0.0148317 (rank : 349)
Query Neighborhood Hits	997	Target Neighborhood Hits	278	Shared Neighborhood Hits	110
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

GAK4_HUMAN
NC score	0.037593 (rank : 1025)	θ value	0.47712 (rank : 498)
Query Neighborhood Hits	997	Target Neighborhood Hits	415	Shared Neighborhood Hits	142
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

SOX13_MOUSE
NC score	0.037549 (rank : 1026)	θ value	0.62314 (rank : 531)
Query Neighborhood Hits	997	Target Neighborhood Hits	495	Shared Neighborhood Hits	147
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

GAK5_HUMAN
NC score	0.037489 (rank : 1027)	θ value	0.62314 (rank : 520)
Query Neighborhood Hits	997	Target Neighborhood Hits	429	Shared Neighborhood Hits	143
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

CUTL1_MOUSE
NC score	0.037230 (rank : 1028)	θ value	0.47712 (rank : 494)
Query Neighborhood Hits	997	Target Neighborhood Hits	1620	Shared Neighborhood Hits	177
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

PKN3_MOUSE
NC score	0.037220 (rank : 1029)	θ value	0.0431538 (rank : 388)
Query Neighborhood Hits	997	Target Neighborhood Hits	1009	Shared Neighborhood Hits	130
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

GRAP_MOUSE
NC score	0.037211 (rank : 1030)	θ value	1.81305 (rank : 620)
Query Neighborhood Hits	997	Target Neighborhood Hits	309	Shared Neighborhood Hits	70
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

GAK11_HUMAN
NC score	0.037186 (rank : 1031)	θ value	0.47712 (rank : 496)
Query Neighborhood Hits	997	Target Neighborhood Hits	409	Shared Neighborhood Hits	138
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK6_HUMAN
NC score	0.037068 (rank : 1032)	θ value	0.62314 (rank : 521)
Query Neighborhood Hits	997	Target Neighborhood Hits	392	Shared Neighborhood Hits	140
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

CRKL_HUMAN
NC score	0.037035 (rank : 1033)	θ value	0.813845 (rank : 536)
Query Neighborhood Hits	997	Target Neighborhood Hits	313	Shared Neighborhood Hits	67
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

PO6F2_MOUSE
NC score	0.036957 (rank : 1034)	θ value	1.81305 (rank : 635)
Query Neighborhood Hits	997	Target Neighborhood Hits	639	Shared Neighborhood Hits	140
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

MAST1_MOUSE
NC score	0.036828 (rank : 1035)	θ value	0.00298849 (rank : 313)
Query Neighborhood Hits	997	Target Neighborhood Hits	1123	Shared Neighborhood Hits	149
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

ECM1_HUMAN
NC score	0.036808 (rank : 1036)	θ value	1.38821 (rank : 594)
Query Neighborhood Hits	997	Target Neighborhood Hits	182	Shared Neighborhood Hits	79
SwissProt Accessions	Q16610	Gene names	ECM1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

GAK2_HUMAN
NC score	0.036800 (rank : 1037)	θ value	0.47712 (rank : 497)
Query Neighborhood Hits	997	Target Neighborhood Hits	406	Shared Neighborhood Hits	137
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

HCN4_MOUSE
NC score	0.036583 (rank : 1038)	θ value	6.88961 (rank : 888)
Query Neighborhood Hits	997	Target Neighborhood Hits	284	Shared Neighborhood Hits	125
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

CRKL_MOUSE
NC score	0.036452 (rank : 1039)	θ value	0.813845 (rank : 537)
Query Neighborhood Hits	997	Target Neighborhood Hits	307	Shared Neighborhood Hits	62
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

OBSCN_HUMAN
NC score	0.036311 (rank : 1040)	θ value	0.365318 (rank : 486)
Query Neighborhood Hits	997	Target Neighborhood Hits	1931	Shared Neighborhood Hits	289
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

MARK3_MOUSE
NC score	0.036205 (rank : 1041)	θ value	8.99809 (rank : 963)
Query Neighborhood Hits	997	Target Neighborhood Hits	919	Shared Neighborhood Hits	93
SwissProt Accessions	Q03141, Q3TM40, Q3V1U3, Q8C6G9, Q8R375, Q9JKE4	Gene names	Mark3, Emk2, Mpk10
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (MPK-10) (ELKL motif kinase 2).

MAP2_HUMAN
NC score	0.036039 (rank : 1042)	θ value	4.03905 (rank : 783)
Query Neighborhood Hits	997	Target Neighborhood Hits	348	Shared Neighborhood Hits	80
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

TGON2_MOUSE
NC score	0.036019 (rank : 1043)	θ value	4.03905 (rank : 802)
Query Neighborhood Hits	997	Target Neighborhood Hits	277	Shared Neighborhood Hits	64
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

GA2L1_MOUSE
NC score	0.035975 (rank : 1044)	θ value	6.88961 (rank : 885)
Query Neighborhood Hits	997	Target Neighborhood Hits	114	Shared Neighborhood Hits	52
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

CRK_HUMAN
NC score	0.035968 (rank : 1045)	θ value	5.27518 (rank : 815)
Query Neighborhood Hits	997	Target Neighborhood Hits	308	Shared Neighborhood Hits	64
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

COCA1_MOUSE
NC score	0.035676 (rank : 1046)	θ value	2.36792 (rank : 663)
Query Neighborhood Hits	997	Target Neighborhood Hits	467	Shared Neighborhood Hits	135
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

PO6F2_HUMAN
NC score	0.035616 (rank : 1047)	θ value	1.06291 (rank : 572)
Query Neighborhood Hits	997	Target Neighborhood Hits	618	Shared Neighborhood Hits	133
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

MAST2_HUMAN
NC score	0.035567 (rank : 1048)	θ value	5.27518 (rank : 831)
Query Neighborhood Hits	997	Target Neighborhood Hits	1189	Shared Neighborhood Hits	169
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

ZAR1_HUMAN
NC score	0.035532 (rank : 1049)	θ value	2.36792 (rank : 699)
Query Neighborhood Hits	997	Target Neighborhood Hits	163	Shared Neighborhood Hits	68
SwissProt Accessions	Q86SH2	Gene names	ZAR1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

HCN2_MOUSE
NC score	0.035326 (rank : 1050)	θ value	2.36792 (rank : 676)
Query Neighborhood Hits	997	Target Neighborhood Hits	278	Shared Neighborhood Hits	131
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

ARHG7_HUMAN
NC score	0.035254 (rank : 1051)	θ value	2.36792 (rank : 656)
Query Neighborhood Hits	997	Target Neighborhood Hits	347	Shared Neighborhood Hits	70
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

MARK3_HUMAN
NC score	0.035133 (rank : 1052)	θ value	5.27518 (rank : 830)
Query Neighborhood Hits	997	Target Neighborhood Hits	893	Shared Neighborhood Hits	91
SwissProt Accessions	P27448, O60219, Q8TB41, Q8WX83, Q96RG1, Q9UMY9, Q9UN34	Gene names	MARK3, CTAK1
Domain Architecture
Description	MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (Cdc25C- associated protein kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein kinase p78) (Ser/Thr protein kinase PAR-1) (Protein kinase STK10).

DCP1A_HUMAN
NC score	0.035101 (rank : 1053)	θ value	3.0926 (rank : 718)
Query Neighborhood Hits	997	Target Neighborhood Hits	228	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

GAK12_HUMAN
NC score	0.034872 (rank : 1054)	θ value	1.38821 (rank : 597)
Query Neighborhood Hits	997	Target Neighborhood Hits	374	Shared Neighborhood Hits	124
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

MK15_HUMAN
NC score	0.034843 (rank : 1055)	θ value	1.81305 (rank : 628)
Query Neighborhood Hits	997	Target Neighborhood Hits	1038	Shared Neighborhood Hits	162
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

TENS1_HUMAN
NC score	0.034786 (rank : 1056)	θ value	4.03905 (rank : 800)
Query Neighborhood Hits	997	Target Neighborhood Hits	400	Shared Neighborhood Hits	110
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

CRK_MOUSE
NC score	0.034192 (rank : 1057)	θ value	6.88961 (rank : 875)
Query Neighborhood Hits	997	Target Neighborhood Hits	314	Shared Neighborhood Hits	67
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

HCN4_HUMAN
NC score	0.033920 (rank : 1058)	θ value	4.03905 (rank : 779)
Query Neighborhood Hits	997	Target Neighborhood Hits	303	Shared Neighborhood Hits	130
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

K1949_MOUSE
NC score	0.033640 (rank : 1059)	θ value	5.27518 (rank : 828)
Query Neighborhood Hits	997	Target Neighborhood Hits	134	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BQ30, Q3UDS6, Q8CEY9, Q8R3D8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1949 homolog.

FA8A1_HUMAN
NC score	0.033584 (rank : 1060)	θ value	0.813845 (rank : 541)
Query Neighborhood Hits	997	Target Neighborhood Hits	53	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UBU6	Gene names	FAM8A1, AHCP
Domain Architecture	No domain graphic available
Description	Protein FAM8A1 (Autosomal highly conserved protein).

COCA1_HUMAN
NC score	0.033508 (rank : 1061)	θ value	3.0926 (rank : 714)
Query Neighborhood Hits	997	Target Neighborhood Hits	458	Shared Neighborhood Hits	125
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

CBL_MOUSE
NC score	0.033477 (rank : 1062)	θ value	0.163984 (rank : 436)
Query Neighborhood Hits	997	Target Neighborhood Hits	426	Shared Neighborhood Hits	90
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

FXL19_MOUSE
NC score	0.033442 (rank : 1063)	θ value	0.0431538 (rank : 382)
Query Neighborhood Hits	997	Target Neighborhood Hits	217	Shared Neighborhood Hits	77
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

CO6A2_HUMAN
NC score	0.033312 (rank : 1064)	θ value	6.88961 (rank : 872)
Query Neighborhood Hits	997	Target Neighborhood Hits	249	Shared Neighborhood Hits	86
SwissProt Accessions	P12110, Q13909, Q13910, Q13911, Q14049, Q16259, Q16597, Q9UML3	Gene names	COL6A2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

DYN1_HUMAN
NC score	0.033311 (rank : 1065)	θ value	0.813845 (rank : 539)
Query Neighborhood Hits	997	Target Neighborhood Hits	216	Shared Neighborhood Hits	109
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

MAGD4_HUMAN
NC score	0.033266 (rank : 1066)	θ value	1.06291 (rank : 568)
Query Neighborhood Hits	997	Target Neighborhood Hits	338	Shared Neighborhood Hits	110
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

CO6A1_HUMAN
NC score	0.033132 (rank : 1067)	θ value	3.0926 (rank : 712)
Query Neighborhood Hits	997	Target Neighborhood Hits	264	Shared Neighborhood Hits	83
SwissProt Accessions	P12109, O00117, O00118, Q14040, Q14041, Q16258	Gene names	COL6A1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

NFM_HUMAN
NC score	0.033053 (rank : 1068)	θ value	1.81305 (rank : 630)
Query Neighborhood Hits	997	Target Neighborhood Hits	1328	Shared Neighborhood Hits	176
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

GR65_HUMAN
NC score	0.032802 (rank : 1069)	θ value	2.36792 (rank : 675)
Query Neighborhood Hits	997	Target Neighborhood Hits	148	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BQQ3, Q8N272, Q96H42	Gene names	GORASP1, GRASP65
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5).

CDT1_HUMAN
NC score	0.032580 (rank : 1070)	θ value	2.36792 (rank : 661)
Query Neighborhood Hits	997	Target Neighborhood Hits	92	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H211, Q86XX9, Q96CJ5, Q96GK5, Q96H67, Q96HE6, Q9BWM0	Gene names	CDT1
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP).

ARRD1_MOUSE
NC score	0.032053 (rank : 1071)	θ value	0.125558 (rank : 416)
Query Neighborhood Hits	997	Target Neighborhood Hits	90	Shared Neighborhood Hits	26
SwissProt Accessions	Q99KN1, Q3TDT6, Q8VEG7	Gene names	Arrdc1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

CO6A2_MOUSE
NC score	0.031903 (rank : 1072)	θ value	6.88961 (rank : 873)
Query Neighborhood Hits	997	Target Neighborhood Hits	260	Shared Neighborhood Hits	84
SwissProt Accessions	Q02788, Q05505	Gene names	Col6a2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

K1688_HUMAN
NC score	0.031841 (rank : 1073)	θ value	0.279714 (rank : 467)
Query Neighborhood Hits	997	Target Neighborhood Hits	217	Shared Neighborhood Hits	77
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

MAVS_MOUSE
NC score	0.031704 (rank : 1074)	θ value	2.36792 (rank : 680)
Query Neighborhood Hits	997	Target Neighborhood Hits	170	Shared Neighborhood Hits	55
SwissProt Accessions	Q8VCF0	Gene names	Mavs, Ips1, Visa
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif).

CT055_HUMAN
NC score	0.031494 (rank : 1075)	θ value	2.36792 (rank : 666)
Query Neighborhood Hits	997	Target Neighborhood Hits	42	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BQ89	Gene names	C20orf55
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf55.

GAK10_HUMAN
NC score	0.030945 (rank : 1076)	θ value	2.36792 (rank : 674)
Query Neighborhood Hits	997	Target Neighborhood Hits	289	Shared Neighborhood Hits	102
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

PGCB_HUMAN
NC score	0.030886 (rank : 1077)	θ value	1.06291 (rank : 571)
Query Neighborhood Hits	997	Target Neighborhood Hits	478	Shared Neighborhood Hits	79
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

3BP2_MOUSE
NC score	0.030756 (rank : 1078)	θ value	5.27518 (rank : 807)
Query Neighborhood Hits	997	Target Neighborhood Hits	142	Shared Neighborhood Hits	43
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

PDXL2_HUMAN
NC score	0.030493 (rank : 1079)	θ value	0.62314 (rank : 527)
Query Neighborhood Hits	997	Target Neighborhood Hits	75	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZ53, Q6UVY4, Q8WUV6	Gene names	PODXL2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

NUP53_HUMAN
NC score	0.030442 (rank : 1080)	θ value	1.81305 (rank : 633)
Query Neighborhood Hits	997	Target Neighborhood Hits	156	Shared Neighborhood Hits	65
SwissProt Accessions	Q8NFH5, Q4ZFZ9, Q53S95, Q8TDJ1	Gene names	NUP35, MP44, NUP53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

USBP1_HUMAN
NC score	0.030355 (rank : 1081)	θ value	0.0736092 (rank : 407)
Query Neighborhood Hits	997	Target Neighborhood Hits	188	Shared Neighborhood Hits	27
SwissProt Accessions	Q8N6Y0, Q8NBX7, Q96KH3, Q9BYI8	Gene names	USHBP1, AIEBP, MCC2
Domain Architecture	No domain graphic available
Description	USH1C-binding protein 1 (Usher syndrome type-1C protein-binding protein 1) (MCC-2) (AIE-75 binding protein).

MARCO_HUMAN
NC score	0.030328 (rank : 1082)	θ value	0.62314 (rank : 523)
Query Neighborhood Hits	997	Target Neighborhood Hits	199	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UEW3, Q9Y5S3	Gene names	MARCO, SCARA2
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure) (Scavenger receptor class A member 2).

FGD1_MOUSE
NC score	0.030273 (rank : 1083)	θ value	5.27518 (rank : 820)
Query Neighborhood Hits	997	Target Neighborhood Hits	387	Shared Neighborhood Hits	136
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

ARHG6_HUMAN
NC score	0.029882 (rank : 1084)	θ value	8.99809 (rank : 926)
Query Neighborhood Hits	997	Target Neighborhood Hits	376	Shared Neighborhood Hits	68
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

SAMD8_HUMAN
NC score	0.029635 (rank : 1085)	θ value	0.365318 (rank : 487)
Query Neighborhood Hits	997	Target Neighborhood Hits	22	Shared Neighborhood Hits	8
SwissProt Accessions	Q96LT4	Gene names	SAMD8
Domain Architecture
Description	Sphingomyelin synthase-related protein 1 (Sterile alpha motif domain- containing 8).

IQEC3_MOUSE
NC score	0.029536 (rank : 1086)	θ value	1.81305 (rank : 622)
Query Neighborhood Hits	997	Target Neighborhood Hits	274	Shared Neighborhood Hits	93
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

NCK2_HUMAN
NC score	0.029416 (rank : 1087)	θ value	0.365318 (rank : 485)
Query Neighborhood Hits	997	Target Neighborhood Hits	310	Shared Neighborhood Hits	64
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

MYO15_MOUSE
NC score	0.029386 (rank : 1088)	θ value	0.813845 (rank : 545)
Query Neighborhood Hits	997	Target Neighborhood Hits	467	Shared Neighborhood Hits	161
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

IF39_HUMAN
NC score	0.029232 (rank : 1089)	θ value	6.88961 (rank : 889)
Query Neighborhood Hits	997	Target Neighborhood Hits	187	Shared Neighborhood Hits	44
SwissProt Accessions	P55884, Q9UMF9	Gene names	EIF3S9
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) (Prt1 homolog) (hPrt1).

DUET_HUMAN
NC score	0.029135 (rank : 1090)	θ value	5.27518 (rank : 818)
Query Neighborhood Hits	997	Target Neighborhood Hits	1220	Shared Neighborhood Hits	124
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

UBP42_HUMAN
NC score	0.029016 (rank : 1091)	θ value	6.88961 (rank : 913)
Query Neighborhood Hits	997	Target Neighborhood Hits	445	Shared Neighborhood Hits	138
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

COEA1_MOUSE
NC score	0.029006 (rank : 1092)	θ value	3.0926 (rank : 715)
Query Neighborhood Hits	997	Target Neighborhood Hits	402	Shared Neighborhood Hits	107
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

TP53B_HUMAN
NC score	0.028965 (rank : 1093)	θ value	4.03905 (rank : 804)
Query Neighborhood Hits	997	Target Neighborhood Hits	413	Shared Neighborhood Hits	68
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

CABL2_MOUSE
NC score	0.028790 (rank : 1094)	θ value	3.0926 (rank : 709)
Query Neighborhood Hits	997	Target Neighborhood Hits	79	Shared Neighborhood Hits	39
SwissProt Accessions	Q8K3M5	Gene names	Cables2
Domain Architecture
Description	CDK5 and ABL1 enzyme substrate 2 (Interactor with CDK3 2) (Ik3-2).

RUSC1_HUMAN
NC score	0.028737 (rank : 1095)	θ value	8.99809 (rank : 972)
Query Neighborhood Hits	997	Target Neighborhood Hits	226	Shared Neighborhood Hits	74
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

MAK_MOUSE
NC score	0.028708 (rank : 1096)	θ value	5.27518 (rank : 829)
Query Neighborhood Hits	997	Target Neighborhood Hits	873	Shared Neighborhood Hits	89
SwissProt Accessions	Q04859	Gene names	Mak, Rck
Domain Architecture
Description	Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male germ cell- associated kinase) (Protein kinase RCK).

CF015_HUMAN
NC score	0.028547 (rank : 1097)	θ value	1.06291 (rank : 552)
Query Neighborhood Hits	997	Target Neighborhood Hits	60	Shared Neighborhood Hits	24
SwissProt Accessions	Q6UXA7, Q5SQ81, Q86Z05, Q9UIG3	Gene names	C6orf15, STG
Domain Architecture	No domain graphic available
Description	Protein C6orf15 precursor (Protein STG).

UROL1_MOUSE
NC score	0.028539 (rank : 1098)	θ value	6.88961 (rank : 914)
Query Neighborhood Hits	997	Target Neighborhood Hits	235	Shared Neighborhood Hits	39
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

RP3A_MOUSE
NC score	0.028387 (rank : 1099)	θ value	4.03905 (rank : 792)
Query Neighborhood Hits	997	Target Neighborhood Hits	510	Shared Neighborhood Hits	164
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

LIPA3_MOUSE
NC score	0.028371 (rank : 1100)	θ value	6.88961 (rank : 894)
Query Neighborhood Hits	997	Target Neighborhood Hits	636	Shared Neighborhood Hits	72
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

KPCE_MOUSE
NC score	0.028361 (rank : 1101)	θ value	3.0926 (rank : 723)
Query Neighborhood Hits	997	Target Neighborhood Hits	906	Shared Neighborhood Hits	87
SwissProt Accessions	P16054	Gene names	Prkce, Pkce, Pkcea
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

CBL_HUMAN
NC score	0.028299 (rank : 1102)	θ value	1.38821 (rank : 588)
Query Neighborhood Hits	997	Target Neighborhood Hits	353	Shared Neighborhood Hits	68
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

KPCE_HUMAN
NC score	0.028219 (rank : 1103)	θ value	2.36792 (rank : 678)
Query Neighborhood Hits	997	Target Neighborhood Hits	906	Shared Neighborhood Hits	88
SwissProt Accessions	Q02156, Q53SL4, Q53SM5, Q9UE81	Gene names	PRKCE, PKCE
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

YETS2_MOUSE
NC score	0.028173 (rank : 1104)	θ value	4.03905 (rank : 806)
Query Neighborhood Hits	997	Target Neighborhood Hits	278	Shared Neighborhood Hits	79
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

BRE1B_HUMAN
NC score	0.028079 (rank : 1105)	θ value	1.38821 (rank : 585)
Query Neighborhood Hits	997	Target Neighborhood Hits	1040	Shared Neighborhood Hits	90
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

SRA1_HUMAN
NC score	0.027897 (rank : 1106)	θ value	1.81305 (rank : 642)
Query Neighborhood Hits	997	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HD15, Q6NVU9, Q8IXM1, Q9HD13, Q9HD14	Gene names	SRA1
Domain Architecture	No domain graphic available
Description	Steroid receptor RNA activator 1 (Steroid receptor RNA activator protein) (SRAP).

SFTPA_MOUSE
NC score	0.027496 (rank : 1107)	θ value	0.47712 (rank : 506)
Query Neighborhood Hits	997	Target Neighborhood Hits	169	Shared Neighborhood Hits	49
SwissProt Accessions	P35242	Gene names	Sftpa1, Sftp-1, Sftp1, Sftpa
Domain Architecture
Description	Pulmonary surfactant-associated protein A precursor (SP-A) (PSP-A) (PSAP).

PRGC2_MOUSE
NC score	0.027248 (rank : 1108)	θ value	2.36792 (rank : 688)
Query Neighborhood Hits	997	Target Neighborhood Hits	225	Shared Neighborhood Hits	48
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

ZMYM3_HUMAN
NC score	0.027228 (rank : 1109)	θ value	3.0926 (rank : 747)
Query Neighborhood Hits	997	Target Neighborhood Hits	223	Shared Neighborhood Hits	57
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

CDKL2_MOUSE
NC score	0.027220 (rank : 1110)	θ value	1.81305 (rank : 613)
Query Neighborhood Hits	997	Target Neighborhood Hits	854	Shared Neighborhood Hits	74
SwissProt Accessions	Q9QUK0, Q3UL60, Q3V3X7, Q9QYI1, Q9QYI2	Gene names	Cdkl2, Kkiamre, Kkm
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Serine/threonine- protein kinase KKIAMRE).

PGCB_MOUSE
NC score	0.027081 (rank : 1111)	θ value	2.36792 (rank : 687)
Query Neighborhood Hits	997	Target Neighborhood Hits	459	Shared Neighborhood Hits	53
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

FOG1_MOUSE
NC score	0.027061 (rank : 1112)	θ value	0.125558 (rank : 421)
Query Neighborhood Hits	997	Target Neighborhood Hits	1237	Shared Neighborhood Hits	246
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

NCOA5_MOUSE
NC score	0.027013 (rank : 1113)	θ value	0.21417 (rank : 459)
Query Neighborhood Hits	997	Target Neighborhood Hits	87	Shared Neighborhood Hits	27
SwissProt Accessions	Q91W39	Gene names	Ncoa5
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA).

FRS3_MOUSE
NC score	0.027008 (rank : 1114)	θ value	3.0926 (rank : 720)
Query Neighborhood Hits	997	Target Neighborhood Hits	168	Shared Neighborhood Hits	78
SwissProt Accessions	Q91WJ0	Gene names	Frs3, Frs2b
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FRS2-beta).

LIPA3_HUMAN
NC score	0.026833 (rank : 1115)	θ value	2.36792 (rank : 679)
Query Neighborhood Hits	997	Target Neighborhood Hits	828	Shared Neighborhood Hits	84
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

FOXN1_HUMAN
NC score	0.026707 (rank : 1116)	θ value	0.47712 (rank : 495)
Query Neighborhood Hits	997	Target Neighborhood Hits	377	Shared Neighborhood Hits	139
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

TSC1_HUMAN
NC score	0.026661 (rank : 1117)	θ value	5.27518 (rank : 852)
Query Neighborhood Hits	997	Target Neighborhood Hits	765	Shared Neighborhood Hits	89
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

DYN3_HUMAN
NC score	0.026619 (rank : 1118)	θ value	6.88961 (rank : 881)
Query Neighborhood Hits	997	Target Neighborhood Hits	158	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

CDKL5_HUMAN
NC score	0.026527 (rank : 1119)	θ value	4.03905 (rank : 762)
Query Neighborhood Hits	997	Target Neighborhood Hits	967	Shared Neighborhood Hits	100
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

SYNP2_HUMAN
NC score	0.026399 (rank : 1120)	θ value	5.27518 (rank : 846)
Query Neighborhood Hits	997	Target Neighborhood Hits	323	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

SFTA2_HUMAN
NC score	0.026262 (rank : 1121)	θ value	0.813845 (rank : 546)
Query Neighborhood Hits	997	Target Neighborhood Hits	169	Shared Neighborhood Hits	50
SwissProt Accessions	Q8IWL1, P07714, Q5RIR8, Q5RIR9	Gene names	SFTPA2, PSAP, SFTP1, SFTPA
Domain Architecture	No domain graphic available
Description	Pulmonary surfactant-associated protein A2 precursor (SP-A2) (SP-A) (PSP-A) (PSPA) (Alveolar proteinosis protein) (35 kDa pulmonary surfactant-associated protein).

SFTA1_HUMAN
NC score	0.025868 (rank : 1122)	θ value	3.0926 (rank : 738)
Query Neighborhood Hits	997	Target Neighborhood Hits	169	Shared Neighborhood Hits	55
SwissProt Accessions	Q8IWL2, P07714, Q5RIR5, Q5RIR7, Q6PIT0, Q8TC19	Gene names	SFTPA1, PSAP, SFTP1, SFTPA
Domain Architecture	No domain graphic available
Description	Pulmonary surfactant-associated protein A1 precursor (SP-A1) (SP-A) (PSP-A) (PSPA) (Alveolar proteinosis protein) (35 kDa pulmonary surfactant-associated protein).

IF4B_HUMAN
NC score	0.025845 (rank : 1123)	θ value	8.99809 (rank : 956)
Query Neighborhood Hits	997	Target Neighborhood Hits	417	Shared Neighborhood Hits	107
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

SNPC4_MOUSE
NC score	0.025794 (rank : 1124)	θ value	2.36792 (rank : 694)
Query Neighborhood Hits	997	Target Neighborhood Hits	237	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

MYO9B_HUMAN
NC score	0.025611 (rank : 1125)	θ value	8.99809 (rank : 966)
Query Neighborhood Hits	997	Target Neighborhood Hits	641	Shared Neighborhood Hits	152
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

ZN687_HUMAN
NC score	0.025471 (rank : 1126)	θ value	0.0252991 (rank : 367)
Query Neighborhood Hits	997	Target Neighborhood Hits	1244	Shared Neighborhood Hits	253
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

AHI1_MOUSE
NC score	0.025245 (rank : 1127)	θ value	5.27518 (rank : 808)
Query Neighborhood Hits	997	Target Neighborhood Hits	496	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

SMCA2_HUMAN
NC score	0.024556 (rank : 1128)	θ value	8.99809 (rank : 976)
Query Neighborhood Hits	997	Target Neighborhood Hits	503	Shared Neighborhood Hits	136
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

RUSC1_MOUSE
NC score	0.024496 (rank : 1129)	θ value	8.99809 (rank : 973)
Query Neighborhood Hits	997	Target Neighborhood Hits	206	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

PCNT_MOUSE
NC score	0.024423 (rank : 1130)	θ value	3.0926 (rank : 731)
Query Neighborhood Hits	997	Target Neighborhood Hits	1207	Shared Neighborhood Hits	95
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

LATS2_HUMAN
NC score	0.024083 (rank : 1131)	θ value	6.88961 (rank : 893)
Query Neighborhood Hits	997	Target Neighborhood Hits	884	Shared Neighborhood Hits	104
SwissProt Accessions	Q9NRM7, Q9P2X1	Gene names	LATS2, KPM
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) (Warts-like kinase).

PER2_MOUSE
NC score	0.024028 (rank : 1132)	θ value	1.38821 (rank : 601)
Query Neighborhood Hits	997	Target Neighborhood Hits	325	Shared Neighborhood Hits	96
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

ZN395_HUMAN
NC score	0.024013 (rank : 1133)	θ value	2.36792 (rank : 700)
Query Neighborhood Hits	997	Target Neighborhood Hits	64	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H8N7, Q6F6H2, Q9BY72, Q9NPB2, Q9NS57, Q9NS58, Q9NS59	Gene names	ZNF395, HDBP2, PBF
Domain Architecture	No domain graphic available
Description	Zinc finger protein 395 (Papillomavirus-binding factor) (Papillomavirus regulatory factor 1) (PRF-1) (Huntington disease gene regulatory region-binding protein 2) (HDBP-2) (HD gene regulatory region-binding protein 2) (HD-regulating factor 2) (HDRF-2).

DOCK4_HUMAN
NC score	0.023944 (rank : 1134)	θ value	1.81305 (rank : 617)
Query Neighborhood Hits	997	Target Neighborhood Hits	237	Shared Neighborhood Hits	83
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

OTU7A_MOUSE
NC score	0.023546 (rank : 1135)	θ value	0.163984 (rank : 441)
Query Neighborhood Hits	997	Target Neighborhood Hits	91	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R554	Gene names	Otud7a, Otud7
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7A (EC 3.-.-.-) (Zinc finger protein Cezanne 2).

SEM6C_MOUSE
NC score	0.023387 (rank : 1136)	θ value	0.279714 (rank : 473)
Query Neighborhood Hits	997	Target Neighborhood Hits	352	Shared Neighborhood Hits	145
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

RASF7_MOUSE
NC score	0.023354 (rank : 1137)	θ value	5.27518 (rank : 838)
Query Neighborhood Hits	997	Target Neighborhood Hits	136	Shared Neighborhood Hits	41
SwissProt Accessions	Q9DD19	Gene names	Rassf7
Domain Architecture
Description	Ras association domain-containing protein 7.

DYN1_MOUSE
NC score	0.023067 (rank : 1138)	θ value	1.38821 (rank : 593)
Query Neighborhood Hits	997	Target Neighborhood Hits	168	Shared Neighborhood Hits	73
SwissProt Accessions	P39053, Q61358, Q61359, Q61360, Q8JZZ4, Q9CSY7, Q9QXX1	Gene names	Dnm1, Dnm
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

LRC56_HUMAN
NC score	0.023043 (rank : 1139)	θ value	4.03905 (rank : 782)
Query Neighborhood Hits	997	Target Neighborhood Hits	165	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IYG6, Q8N3Q4	Gene names	LRRC56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

NBR1_MOUSE
NC score	0.022993 (rank : 1140)	θ value	3.0926 (rank : 728)
Query Neighborhood Hits	997	Target Neighborhood Hits	116	Shared Neighborhood Hits	25
SwissProt Accessions	P97432, Q9JIH9	Gene names	Nbr1, M17s2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2).

SIX5_MOUSE
NC score	0.022957 (rank : 1141)	θ value	0.62314 (rank : 530)
Query Neighborhood Hits	997	Target Neighborhood Hits	354	Shared Neighborhood Hits	62
SwissProt Accessions	P70178	Gene names	Six5, Dmahp
Domain Architecture
Description	Homeobox protein SIX5 (DM locus-associated homeodomain protein homolog).

BTBD7_MOUSE
NC score	0.022617 (rank : 1142)	θ value	0.21417 (rank : 450)
Query Neighborhood Hits	997	Target Neighborhood Hits	228	Shared Neighborhood Hits	37
SwissProt Accessions	Q8CFE5, Q80TC3, Q8BZY9	Gene names	Btbd7, Kiaa1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

ARRD1_HUMAN
NC score	0.022427 (rank : 1143)	θ value	4.03905 (rank : 757)
Query Neighborhood Hits	997	Target Neighborhood Hits	75	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N5I2	Gene names	ARRDC1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

ADA12_MOUSE
NC score	0.022316 (rank : 1144)	θ value	0.365318 (rank : 477)
Query Neighborhood Hits	997	Target Neighborhood Hits	474	Shared Neighborhood Hits	140
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

HDAC9_MOUSE
NC score	0.022246 (rank : 1145)	θ value	1.06291 (rank : 561)
Query Neighborhood Hits	997	Target Neighborhood Hits	186	Shared Neighborhood Hits	22
SwissProt Accessions	Q99N13, Q9EPT2	Gene names	Hdac9, Hdac7b, Hdrp, Mitr
Domain Architecture	No domain graphic available
Description	Histone deacetylase 9 (HD9) (HD7B) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR).

NDE1_HUMAN
NC score	0.022128 (rank : 1146)	θ value	6.88961 (rank : 898)
Query Neighborhood Hits	997	Target Neighborhood Hits	823	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

FOG1_HUMAN
NC score	0.021894 (rank : 1147)	θ value	4.03905 (rank : 777)
Query Neighborhood Hits	997	Target Neighborhood Hits	981	Shared Neighborhood Hits	156
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

CTND2_HUMAN
NC score	0.021697 (rank : 1148)	θ value	4.03905 (rank : 771)
Query Neighborhood Hits	997	Target Neighborhood Hits	333	Shared Neighborhood Hits	95
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

GAK8_HUMAN
NC score	0.021551 (rank : 1149)	θ value	6.88961 (rank : 886)
Query Neighborhood Hits	997	Target Neighborhood Hits	145	Shared Neighborhood Hits	57
SwissProt Accessions	Q9HDB9	Gene names	ERVK5
Domain Architecture	No domain graphic available
Description	HERV-K_3q12.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(II) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

ETV3_HUMAN
NC score	0.021543 (rank : 1150)	θ value	1.38821 (rank : 596)
Query Neighborhood Hits	997	Target Neighborhood Hits	312	Shared Neighborhood Hits	80
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

DOS_HUMAN
NC score	0.021166 (rank : 1151)	θ value	5.27518 (rank : 817)
Query Neighborhood Hits	997	Target Neighborhood Hits	68	Shared Neighborhood Hits	19
SwissProt Accessions	Q8N350, O43385	Gene names	DOS, C19orf26
Domain Architecture	No domain graphic available
Description	Protein Dos.

HXA3_MOUSE
NC score	0.021127 (rank : 1152)	θ value	1.06291 (rank : 562)
Query Neighborhood Hits	997	Target Neighborhood Hits	558	Shared Neighborhood Hits	133
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

DYN2_HUMAN
NC score	0.021044 (rank : 1153)	θ value	6.88961 (rank : 880)
Query Neighborhood Hits	997	Target Neighborhood Hits	112	Shared Neighborhood Hits	42
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

SYNG_MOUSE
NC score	0.020974 (rank : 1154)	θ value	6.88961 (rank : 907)
Query Neighborhood Hits	997	Target Neighborhood Hits	206	Shared Neighborhood Hits	56
SwissProt Accessions	Q5SV85, Q5SV84, Q6PHT6	Gene names	Ap1gbp1, Syng
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

SOX17_MOUSE
NC score	0.020944 (rank : 1155)	θ value	0.47712 (rank : 507)
Query Neighborhood Hits	997	Target Neighborhood Hits	223	Shared Neighborhood Hits	73
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

GGA3_HUMAN
NC score	0.020934 (rank : 1156)	θ value	1.06291 (rank : 559)
Query Neighborhood Hits	997	Target Neighborhood Hits	127	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NZ52, Q15017, Q6IS16, Q9UJY3	Gene names	GGA3, KIAA0154
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

DOK2_MOUSE
NC score	0.020929 (rank : 1157)	θ value	6.88961 (rank : 879)
Query Neighborhood Hits	997	Target Neighborhood Hits	244	Shared Neighborhood Hits	84
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

GP152_HUMAN
NC score	0.020756 (rank : 1158)	θ value	8.99809 (rank : 950)
Query Neighborhood Hits	997	Target Neighborhood Hits	636	Shared Neighborhood Hits	128
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

DUS8_HUMAN
NC score	0.020456 (rank : 1159)	θ value	3.0926 (rank : 719)
Query Neighborhood Hits	997	Target Neighborhood Hits	161	Shared Neighborhood Hits	60
SwissProt Accessions	Q13202	Gene names	DUSP8, VH5
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH-5).

ECM1_MOUSE
NC score	0.020272 (rank : 1160)	θ value	4.03905 (rank : 772)
Query Neighborhood Hits	997	Target Neighborhood Hits	105	Shared Neighborhood Hits	35
SwissProt Accessions	Q61508	Gene names	Ecm1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

PME17_HUMAN
NC score	0.019749 (rank : 1161)	θ value	1.81305 (rank : 634)
Query Neighborhood Hits	997	Target Neighborhood Hits	95	Shared Neighborhood Hits	29
SwissProt Accessions	P40967, Q12763, Q14448, Q14817, Q16565	Gene names	SILV, D12S53E, PMEL17
Domain Architecture
Description	Melanocyte protein Pmel 17 precursor (Melanocyte lineage-specific antigen GP100) (Melanoma-associated ME20 antigen) (ME20M/ME20S) (ME20- M/ME20-S) (95 kDa melanocyte-specific secreted glycoprotein).

MRIP_HUMAN
NC score	0.019729 (rank : 1162)	θ value	8.99809 (rank : 965)
Query Neighborhood Hits	997	Target Neighborhood Hits	578	Shared Neighborhood Hits	67
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

MYO1F_HUMAN
NC score	0.019495 (rank : 1163)	θ value	4.03905 (rank : 786)
Query Neighborhood Hits	997	Target Neighborhood Hits	275	Shared Neighborhood Hits	80
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

DOCK4_MOUSE
NC score	0.019475 (rank : 1164)	θ value	6.88961 (rank : 878)
Query Neighborhood Hits	997	Target Neighborhood Hits	210	Shared Neighborhood Hits	68
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

EGLN1_MOUSE
NC score	0.019466 (rank : 1165)	θ value	4.03905 (rank : 773)
Query Neighborhood Hits	997	Target Neighborhood Hits	88	Shared Neighborhood Hits	31
SwissProt Accessions	Q91YE3, Q8VHJ2, Q922P3	Gene names	Egln1
Domain Architecture
Description	Egl nine homolog 1 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-prolyl hydroxylase 2) (HIF-PH2) (HPH-2) (SM-20).

TBC10_MOUSE
NC score	0.019428 (rank : 1166)	θ value	0.21417 (rank : 462)
Query Neighborhood Hits	997	Target Neighborhood Hits	94	Shared Neighborhood Hits	28
SwissProt Accessions	P58802	Gene names	Tbc1d10a, Epi64, Tbc1d10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

S2A4R_HUMAN
NC score	0.019414 (rank : 1167)	θ value	5.27518 (rank : 842)
Query Neighborhood Hits	997	Target Neighborhood Hits	54	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NR83, Q6F6I6, Q6F6I7, Q6GTK5, Q8TAH5, Q8WVW7, Q96QD3, Q9BV85	Gene names	SLC2A4RG, HDBP1
Domain Architecture	No domain graphic available
Description	SLC2A4 regulator (GLUT4 enhancer factor) (GEF) (Huntington disease gene regulatory region-binding protein 1) (HDBP-1).

AIRE_MOUSE
NC score	0.019379 (rank : 1168)	θ value	6.88961 (rank : 861)
Query Neighborhood Hits	997	Target Neighborhood Hits	196	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

TR19L_HUMAN
NC score	0.019245 (rank : 1169)	θ value	1.81305 (rank : 645)
Query Neighborhood Hits	997	Target Neighborhood Hits	99	Shared Neighborhood Hits	21
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

PER2_HUMAN
NC score	0.019206 (rank : 1170)	θ value	6.88961 (rank : 901)
Query Neighborhood Hits	997	Target Neighborhood Hits	170	Shared Neighborhood Hits	49
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

LZTS2_MOUSE
NC score	0.019204 (rank : 1171)	θ value	8.99809 (rank : 961)
Query Neighborhood Hits	997	Target Neighborhood Hits	423	Shared Neighborhood Hits	64
SwissProt Accessions	Q91YU6, Q569X6	Gene names	Lzts2, Kiaa1813
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2.

EMIL1_HUMAN
NC score	0.018826 (rank : 1172)	θ value	4.03905 (rank : 774)
Query Neighborhood Hits	997	Target Neighborhood Hits	239	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y6C2, Q96G58, Q9UG76	Gene names	EMILIN1, EMI
Domain Architecture
Description	EMILIN-1 precursor (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1).

RBP1_HUMAN
NC score	0.018735 (rank : 1173)	θ value	8.99809 (rank : 971)
Query Neighborhood Hits	997	Target Neighborhood Hits	521	Shared Neighborhood Hits	50
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

PLXB1_MOUSE
NC score	0.018697 (rank : 1174)	θ value	0.62314 (rank : 528)
Query Neighborhood Hits	997	Target Neighborhood Hits	259	Shared Neighborhood Hits	87
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

MMTA2_HUMAN
NC score	0.018691 (rank : 1175)	θ value	1.38821 (rank : 599)
Query Neighborhood Hits	997	Target Neighborhood Hits	40	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BU76, Q6P5Y0, Q6ZTZ6, Q6ZWA6, Q8IZH3	Gene names	MMTAG2, C1orf35
Domain Architecture	No domain graphic available
Description	Multiple myeloma tumor-associated protein 2 (hMMTAG2).

BAIP2_HUMAN
NC score	0.018673 (rank : 1176)	θ value	2.36792 (rank : 659)
Query Neighborhood Hits	997	Target Neighborhood Hits	192	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43	Gene names	BAIAP2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Protein BAP2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor substrate p53/p58) (IRSp53/58) (IRS-58) (Fas ligand-associated factor 3) (FLAF3).

SNRPA_MOUSE
NC score	0.018567 (rank : 1177)	θ value	8.99809 (rank : 978)
Query Neighborhood Hits	997	Target Neighborhood Hits	129	Shared Neighborhood Hits	22
SwissProt Accessions	Q62189, Q52LA2	Gene names	Snrpa, Rnu1a-1
Domain Architecture
Description	U1 small nuclear ribonucleoprotein A (U1 snRNP protein A) (U1A protein) (U1-A).

TBC10_HUMAN
NC score	0.018154 (rank : 1178)	θ value	0.62314 (rank : 533)
Query Neighborhood Hits	997	Target Neighborhood Hits	64	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BXI6, O76053, Q543A2	Gene names	TBC1D10A, EPI64, TBC1D10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

MA1B1_HUMAN
NC score	0.018148 (rank : 1179)	θ value	3.0926 (rank : 726)
Query Neighborhood Hits	997	Target Neighborhood Hits	125	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UKM7, Q5VSG3, Q9BRS9, Q9Y5K7	Gene names	MAN1B1
Domain Architecture
Description	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific-processing alpha-mannosidase).

SNRPA_HUMAN
NC score	0.017682 (rank : 1180)	θ value	8.99809 (rank : 977)
Query Neighborhood Hits	997	Target Neighborhood Hits	128	Shared Neighborhood Hits	23
SwissProt Accessions	P09012	Gene names	SNRPA
Domain Architecture
Description	U1 small nuclear ribonucleoprotein A (U1 snRNP protein A) (U1A protein) (U1-A).

OBF1_MOUSE
NC score	0.017656 (rank : 1181)	θ value	3.0926 (rank : 730)
Query Neighborhood Hits	997	Target Neighborhood Hits	73	Shared Neighborhood Hits	22
SwissProt Accessions	Q64693	Gene names	Pou2af1, Obf-1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (BOB1) (OCA-B).

ARHG1_MOUSE
NC score	0.017612 (rank : 1182)	θ value	6.88961 (rank : 863)
Query Neighborhood Hits	997	Target Neighborhood Hits	266	Shared Neighborhood Hits	108
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

TOPB1_MOUSE
NC score	0.017134 (rank : 1183)	θ value	6.88961 (rank : 909)
Query Neighborhood Hits	997	Target Neighborhood Hits	89	Shared Neighborhood Hits	30
SwissProt Accessions	Q6ZQF0, Q6P6P0, Q80Y33, Q8BUI0, Q8BUK1, Q8R348, Q91VX3, Q922X8	Gene names	Topbp1, Kiaa0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase II-binding protein 1 (DNA topoisomerase IIbeta- binding protein 1) (TopBP1).

DUS8_MOUSE
NC score	0.017097 (rank : 1184)	θ value	2.36792 (rank : 669)
Query Neighborhood Hits	997	Target Neighborhood Hits	119	Shared Neighborhood Hits	33
SwissProt Accessions	O09112	Gene names	Dusp8, Nttp1
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Neuronal tyrosine threonine phosphatase 1).

ZN516_MOUSE
NC score	0.017086 (rank : 1185)	θ value	9.92553e-07 (rank : 218)
Query Neighborhood Hits	997	Target Neighborhood Hits	1197	Shared Neighborhood Hits	230
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

ATF7_HUMAN
NC score	0.016630 (rank : 1186)	θ value	4.03905 (rank : 759)
Query Neighborhood Hits	997	Target Neighborhood Hits	333	Shared Neighborhood Hits	55
SwissProt Accessions	P17544, Q13814	Gene names	ATF7, ATFA
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

AKAP1_MOUSE
NC score	0.016602 (rank : 1187)	θ value	4.03905 (rank : 754)
Query Neighborhood Hits	997	Target Neighborhood Hits	198	Shared Neighborhood Hits	49
SwissProt Accessions	O08715, O08714, P97488	Gene names	Akap1, Akap
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein) (S-AKAP).

BAIP2_MOUSE
NC score	0.016506 (rank : 1188)	θ value	3.0926 (rank : 706)
Query Neighborhood Hits	997	Target Neighborhood Hits	185	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BKX1, Q91V97, Q923V9, Q923W0	Gene names	Baiap2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor tyrosine kinase 53 kDa substrate).

TAF6L_MOUSE
NC score	0.016371 (rank : 1189)	θ value	8.99809 (rank : 985)
Query Neighborhood Hits	997	Target Neighborhood Hits	146	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R2K4, Q8C5T2	Gene names	Taf6l, Paf65a
Domain Architecture
Description	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65 alpha) (PAF65- alpha).

ATF6B_HUMAN
NC score	0.016138 (rank : 1190)	θ value	2.36792 (rank : 657)
Query Neighborhood Hits	997	Target Neighborhood Hits	122	Shared Neighborhood Hits	36
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).

TF3C2_MOUSE
NC score	0.015930 (rank : 1191)	θ value	4.03905 (rank : 801)
Query Neighborhood Hits	997	Target Neighborhood Hits	165	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BL74, Q3U7Z9, Q80XQ7, Q8BJJ4, Q8BLP3, Q8K1J1, Q9CSS0, Q9CVE6, Q9DBK6	Gene names	Gtf3c2, Kiaa0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

JPH1_MOUSE
NC score	0.015900 (rank : 1192)	θ value	8.99809 (rank : 960)
Query Neighborhood Hits	997	Target Neighborhood Hits	120	Shared Neighborhood Hits	37
SwissProt Accessions	Q9ET80, Q9EQZ3	Gene names	Jph1, Jp1
Domain Architecture
Description	Junctophilin-1 (Junctophilin type 1) (JP-1).

ZF106_MOUSE
NC score	0.015491 (rank : 1193)	θ value	0.365318 (rank : 492)
Query Neighborhood Hits	997	Target Neighborhood Hits	472	Shared Neighborhood Hits	53
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

BAI1_HUMAN
NC score	0.015374 (rank : 1194)	θ value	2.36792 (rank : 658)
Query Neighborhood Hits	997	Target Neighborhood Hits	375	Shared Neighborhood Hits	97
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

JHD3B_MOUSE
NC score	0.015355 (rank : 1195)	θ value	8.99809 (rank : 958)
Query Neighborhood Hits	997	Target Neighborhood Hits	152	Shared Neighborhood Hits	55
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

HDAC9_HUMAN
NC score	0.015265 (rank : 1196)	θ value	1.06291 (rank : 560)
Query Neighborhood Hits	997	Target Neighborhood Hits	201	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UKV0, O94845, O95028	Gene names	HDAC9, HDAC7, HDAC7B, KIAA0744
Domain Architecture
Description	Histone deacetylase 9 (HD9) (HD7B) (HD7).

AKAP6_HUMAN
NC score	0.015218 (rank : 1197)	θ value	4.03905 (rank : 755)
Query Neighborhood Hits	997	Target Neighborhood Hits	263	Shared Neighborhood Hits	26
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

CP007_MOUSE
NC score	0.015175 (rank : 1198)	θ value	8.99809 (rank : 938)
Query Neighborhood Hits	997	Target Neighborhood Hits	231	Shared Neighborhood Hits	51
SwissProt Accessions	Q8C190, Q6PFD1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 homolog (5-day ovary-specific transcript 1 protein).

US6NL_HUMAN
NC score	0.015038 (rank : 1199)	θ value	8.99809 (rank : 994)
Query Neighborhood Hits	997	Target Neighborhood Hits	201	Shared Neighborhood Hits	52
SwissProt Accessions	Q92738, Q15400, Q7L0K9	Gene names	USP6NL, KIAA0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN- tre).

TLE1_HUMAN
NC score	0.015030 (rank : 1200)	θ value	2.36792 (rank : 696)
Query Neighborhood Hits	997	Target Neighborhood Hits	485	Shared Neighborhood Hits	116
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

TNR3_HUMAN
NC score	0.014954 (rank : 1201)	θ value	0.813845 (rank : 547)
Query Neighborhood Hits	997	Target Neighborhood Hits	145	Shared Neighborhood Hits	28
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

FREA_HUMAN
NC score	0.014922 (rank : 1202)	θ value	8.99809 (rank : 948)
Query Neighborhood Hits	997	Target Neighborhood Hits	205	Shared Neighborhood Hits	74
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

SEM6B_MOUSE
NC score	0.014894 (rank : 1203)	θ value	1.81305 (rank : 637)
Query Neighborhood Hits	997	Target Neighborhood Hits	200	Shared Neighborhood Hits	79
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

CNGB1_HUMAN
NC score	0.014798 (rank : 1204)	θ value	4.03905 (rank : 763)
Query Neighborhood Hits	997	Target Neighborhood Hits	222	Shared Neighborhood Hits	50
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

HASP_MOUSE
NC score	0.014691 (rank : 1205)	θ value	1.38821 (rank : 598)
Query Neighborhood Hits	997	Target Neighborhood Hits	50	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z0R0, Q99MU9, Q9JJJ4	Gene names	Gsg2
Domain Architecture
Description	Serine/threonine-protein kinase Haspin (EC 2.7.11.1) (Haploid germ cell-specific nuclear protein kinase) (Germ cell-specific gene 2 protein).

SMAD1_HUMAN
NC score	0.014681 (rank : 1206)	θ value	1.81305 (rank : 639)
Query Neighborhood Hits	997	Target Neighborhood Hits	59	Shared Neighborhood Hits	19
SwissProt Accessions	Q15797, Q16636	Gene names	SMAD1, BSP1, MADH1, MADR1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Transforming growth factor- beta signaling protein 1) (BSP-1) (hSMAD1) (JV4-1).

ARI3A_HUMAN
NC score	0.014592 (rank : 1207)	θ value	3.0926 (rank : 703)
Query Neighborhood Hits	997	Target Neighborhood Hits	80	Shared Neighborhood Hits	22
SwissProt Accessions	Q99856, Q8IZA7	Gene names	ARID3A, DRIL1, DRX, E2FBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 3A (ARID domain- containing protein 3A) (B-cell regulator of IgH transcription) (Bright) (E2F-binding protein 1).

OXRP_HUMAN
NC score	0.014461 (rank : 1208)	θ value	8.99809 (rank : 967)
Query Neighborhood Hits	997	Target Neighborhood Hits	544	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

BUB1B_HUMAN
NC score	0.014257 (rank : 1209)	θ value	6.88961 (rank : 865)
Query Neighborhood Hits	997	Target Neighborhood Hits	208	Shared Neighborhood Hits	27
SwissProt Accessions	O60566, O60501, O60627, O60758, O75389, Q96KM4	Gene names	BUB1B, BUBR1, MAD3L
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (hBUBR1) (MAD3/BUB1-related protein kinase) (Mitotic checkpoint kinase MAD3L) (SSK1).

PP1R8_HUMAN
NC score	0.014218 (rank : 1210)	θ value	3.0926 (rank : 735)
Query Neighborhood Hits	997	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	Q12972, Q5TIF2, Q6PKF6, Q9UBH1, Q9UBZ0	Gene names	PPP1R8, ARD1, NIPP1
Domain Architecture
Description	Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8) [Includes: Activator of RNA decay (EC 3.1.4.-) (ARD-1)].

CEBPE_HUMAN
NC score	0.014136 (rank : 1211)	θ value	3.0926 (rank : 711)
Query Neighborhood Hits	997	Target Neighborhood Hits	236	Shared Neighborhood Hits	63
SwissProt Accessions	Q15744, Q15745, Q8IYI2, Q99803	Gene names	CEBPE
Domain Architecture
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

TLE1_MOUSE
NC score	0.014125 (rank : 1212)	θ value	4.03905 (rank : 803)
Query Neighborhood Hits	997	Target Neighborhood Hits	491	Shared Neighborhood Hits	116
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

PO6F1_MOUSE
NC score	0.013929 (rank : 1213)	θ value	4.03905 (rank : 788)
Query Neighborhood Hits	997	Target Neighborhood Hits	581	Shared Neighborhood Hits	102
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

DC1L2_MOUSE
NC score	0.013679 (rank : 1214)	θ value	5.27518 (rank : 816)
Query Neighborhood Hits	997	Target Neighborhood Hits	173	Shared Neighborhood Hits	59
SwissProt Accessions	Q6PDL0	Gene names	Dync1li2, Dncli2, Dnclic2
Domain Architecture	No domain graphic available
Description	Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic).

VAV3_HUMAN
NC score	0.013531 (rank : 1215)	θ value	5.27518 (rank : 855)
Query Neighborhood Hits	997	Target Neighborhood Hits	398	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

SMAD1_MOUSE
NC score	0.013365 (rank : 1216)	θ value	4.03905 (rank : 795)
Query Neighborhood Hits	997	Target Neighborhood Hits	56	Shared Neighborhood Hits	18
SwissProt Accessions	P70340, P70442, Q9CYK6	Gene names	Smad1, Madh1, Madr1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Mothers-against-DPP-related 1) (mMad1) (Dwarfin-A) (Dwf-A).

SMAD5_MOUSE
NC score	0.013198 (rank : 1217)	θ value	8.99809 (rank : 974)
Query Neighborhood Hits	997	Target Neighborhood Hits	74	Shared Neighborhood Hits	24
SwissProt Accessions	P97454, P70341, Q810K0	Gene names	Smad5, Madh5, Msmad5
Domain Architecture
Description	Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) (mSmad5) (Dwarfin-C) (Dwf-C).

ANXA7_HUMAN
NC score	0.013168 (rank : 1218)	θ value	6.88961 (rank : 862)
Query Neighborhood Hits	997	Target Neighborhood Hits	168	Shared Neighborhood Hits	72
SwissProt Accessions	P20073	Gene names	ANXA7, ANX7, SNX
Domain Architecture
Description	Annexin A7 (Annexin VII) (Synexin).

FOXL2_MOUSE
NC score	0.013022 (rank : 1219)	θ value	0.813845 (rank : 543)
Query Neighborhood Hits	997	Target Neighborhood Hits	151	Shared Neighborhood Hits	50
SwissProt Accessions	O88470, Q8K3X9	Gene names	Foxl2, Pfrk
Domain Architecture	No domain graphic available
Description	Forkhead box protein L2 (Pituitary forkhead factor) (P-Frk).

TPP2_MOUSE
NC score	0.012728 (rank : 1220)	θ value	5.27518 (rank : 851)
Query Neighborhood Hits	997	Target Neighborhood Hits	24	Shared Neighborhood Hits	8
SwissProt Accessions	Q64514	Gene names	Tpp2
Domain Architecture
Description	Tripeptidyl-peptidase 2 (EC 3.4.14.10) (Tripeptidyl-peptidase II) (TPP-II) (Tripeptidyl aminopeptidase).

RPGF1_HUMAN
NC score	0.012705 (rank : 1221)	θ value	3.0926 (rank : 737)
Query Neighborhood Hits	997	Target Neighborhood Hits	262	Shared Neighborhood Hits	82
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

VAV3_MOUSE
NC score	0.012620 (rank : 1222)	θ value	8.99809 (rank : 995)
Query Neighborhood Hits	997	Target Neighborhood Hits	404	Shared Neighborhood Hits	66
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

PHF12_MOUSE
NC score	0.012610 (rank : 1223)	θ value	3.0926 (rank : 734)
Query Neighborhood Hits	997	Target Neighborhood Hits	172	Shared Neighborhood Hits	39
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

CAC1H_HUMAN
NC score	0.012545 (rank : 1224)	θ value	1.81305 (rank : 611)
Query Neighborhood Hits	997	Target Neighborhood Hits	307	Shared Neighborhood Hits	81
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

DDX51_HUMAN
NC score	0.012241 (rank : 1225)	θ value	8.99809 (rank : 942)
Query Neighborhood Hits	997	Target Neighborhood Hits	332	Shared Neighborhood Hits	71
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

MMP9_HUMAN
NC score	0.012226 (rank : 1226)	θ value	2.36792 (rank : 682)
Query Neighborhood Hits	997	Target Neighborhood Hits	125	Shared Neighborhood Hits	33
SwissProt Accessions	P14780, Q3LR70, Q8N725, Q9H4Z1	Gene names	MMP9, CLG4B
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB) [Contains: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9].

TMM24_MOUSE
NC score	0.012220 (rank : 1227)	θ value	2.36792 (rank : 697)
Query Neighborhood Hits	997	Target Neighborhood Hits	65	Shared Neighborhood Hits	18
SwissProt Accessions	Q80X80	Gene names	Tmem24
Domain Architecture	No domain graphic available
Description	Transmembrane protein 24.

BUB1B_MOUSE
NC score	0.012055 (rank : 1228)	θ value	6.88961 (rank : 866)
Query Neighborhood Hits	997	Target Neighborhood Hits	202	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Z1S0	Gene names	Bub1b, Mad3l
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (Mitotic checkpoint kinase MAD3L).

NLGN3_MOUSE
NC score	0.011958 (rank : 1229)	θ value	0.279714 (rank : 471)
Query Neighborhood Hits	997	Target Neighborhood Hits	48	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BYM5, Q8BXR4	Gene names	Nlgn3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

NR4A3_MOUSE
NC score	0.011759 (rank : 1230)	θ value	0.163984 (rank : 440)
Query Neighborhood Hits	997	Target Neighborhood Hits	127	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QZB6, Q9QZB5	Gene names	Nr4a3, Tec
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Orphan nuclear receptor TEC) (Translocated in extraskeletal chondrosarcoma).

ATBF1_MOUSE
NC score	0.011717 (rank : 1231)	θ value	3.0926 (rank : 704)
Query Neighborhood Hits	997	Target Neighborhood Hits	1841	Shared Neighborhood Hits	239
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

PP1R8_MOUSE
NC score	0.011607 (rank : 1232)	θ value	8.99809 (rank : 969)
Query Neighborhood Hits	997	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R3G1, Q8C087	Gene names	Ppp1r8, Nipp1
Domain Architecture	No domain graphic available
Description	Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8).

TSNA1_HUMAN
NC score	0.011411 (rank : 1233)	θ value	5.27518 (rank : 853)
Query Neighborhood Hits	997	Target Neighborhood Hits	178	Shared Neighborhood Hits	37
SwissProt Accessions	Q96NA8	Gene names	TSNARE1
Domain Architecture	No domain graphic available
Description	t-SNARE domain-containing protein 1.

PCOC1_HUMAN
NC score	0.011281 (rank : 1234)	θ value	0.47712 (rank : 505)
Query Neighborhood Hits	997	Target Neighborhood Hits	146	Shared Neighborhood Hits	34
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

NFAC2_MOUSE
NC score	0.011234 (rank : 1235)	θ value	3.0926 (rank : 729)
Query Neighborhood Hits	997	Target Neighborhood Hits	98	Shared Neighborhood Hits	28
SwissProt Accessions	Q60591, Q60984, Q60985	Gene names	Nfatc2, Nfat1, Nfatp
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).

NLGN3_HUMAN
NC score	0.011136 (rank : 1236)	θ value	0.62314 (rank : 525)
Query Neighborhood Hits	997	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZ94, Q8NCD0, Q9NZ95, Q9NZ96, Q9NZ97, Q9P248	Gene names	NLGN3, KIAA1480, NL3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

TPP2_HUMAN
NC score	0.010962 (rank : 1237)	θ value	8.99809 (rank : 991)
Query Neighborhood Hits	997	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	P29144	Gene names	TPP2
Domain Architecture
Description	Tripeptidyl-peptidase 2 (EC 3.4.14.10) (Tripeptidyl-peptidase II) (TPP-II) (Tripeptidyl aminopeptidase).

SMAL1_HUMAN
NC score	0.010894 (rank : 1238)	θ value	4.03905 (rank : 796)
Query Neighborhood Hits	997	Target Neighborhood Hits	174	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

RP1L1_MOUSE
NC score	0.010281 (rank : 1239)	θ value	5.27518 (rank : 840)
Query Neighborhood Hits	997	Target Neighborhood Hits	170	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

KCNH6_HUMAN
NC score	0.010133 (rank : 1240)	θ value	4.03905 (rank : 780)
Query Neighborhood Hits	997	Target Neighborhood Hits	222	Shared Neighborhood Hits	64
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

RAVR1_MOUSE
NC score	0.010087 (rank : 1241)	θ value	3.0926 (rank : 736)
Query Neighborhood Hits	997	Target Neighborhood Hits	179	Shared Neighborhood Hits	29
SwissProt Accessions	Q9CW46, Q5DTT6, Q811K0, Q8C3Z1, Q8CA14	Gene names	Raver1, Kiaa1978
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 1 (Protein raver-1).

FOXL2_HUMAN
NC score	0.009883 (rank : 1242)	θ value	1.81305 (rank : 619)
Query Neighborhood Hits	997	Target Neighborhood Hits	142	Shared Neighborhood Hits	40
SwissProt Accessions	P58012, Q4ZGJ3	Gene names	FOXL2
Domain Architecture
Description	Forkhead box protein L2.

ELL_HUMAN
NC score	0.009857 (rank : 1243)	θ value	6.88961 (rank : 883)
Query Neighborhood Hits	997	Target Neighborhood Hits	183	Shared Neighborhood Hits	55
SwissProt Accessions	P55199	Gene names	ELL, C19orf17
Domain Architecture
Description	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein).

DPOLL_MOUSE
NC score	0.009495 (rank : 1244)	θ value	8.99809 (rank : 945)
Query Neighborhood Hits	997	Target Neighborhood Hits	71	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QXE2, Q9CTJ1	Gene names	Poll, Polk
Domain Architecture
Description	DNA polymerase lambda (EC 2.7.7.7) (EC 4.2.99.-) (Pol Lambda) (DNA polymerase kappa).

FOXK2_HUMAN
NC score	0.009489 (rank : 1245)	θ value	5.27518 (rank : 823)
Query Neighborhood Hits	997	Target Neighborhood Hits	190	Shared Neighborhood Hits	50
SwissProt Accessions	Q01167, Q13622, Q13623, Q13624	Gene names	FOXK2, ILF, ILF1
Domain Architecture
Description	Forkhead box protein K2 (Interleukin enhancer-binding factor 1) (Cellular transcription factor ILF-1).

MORC4_MOUSE
NC score	0.009416 (rank : 1246)	θ value	4.03905 (rank : 785)
Query Neighborhood Hits	997	Target Neighborhood Hits	235	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BMD7, Q4KMM6, Q8BX95, Q9CS96	Gene names	Morc4, Zcwcc2
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 4 (Zinc finger CW-type coiled- coil domain protein 2).

GLUD1_MOUSE
NC score	0.009161 (rank : 1247)	θ value	8.99809 (rank : 949)
Query Neighborhood Hits	997	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CIX8	Gene names	Gluld1, Lgs
Domain Architecture	No domain graphic available
Description	Glutamate--ammonia ligase domain-containing protein 1 (Lengsin) (Lens glutamine synthase-like).

SOX5_MOUSE
NC score	0.008966 (rank : 1248)	θ value	3.0926 (rank : 741)
Query Neighborhood Hits	997	Target Neighborhood Hits	196	Shared Neighborhood Hits	26
SwissProt Accessions	P35710, O88184, O89018	Gene names	Sox5, Sox-5
Domain Architecture
Description	Transcription factor SOX-5.

DHX37_HUMAN
NC score	0.008949 (rank : 1249)	θ value	2.36792 (rank : 667)
Query Neighborhood Hits	997	Target Neighborhood Hits	133	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IY37, Q9BUI7, Q9P211	Gene names	DHX37, DDX37, KIAA1517
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX37 (EC 3.6.1.-) (DEAH box protein 37).

NCOA1_MOUSE
NC score	0.008808 (rank : 1250)	θ value	5.27518 (rank : 832)
Query Neighborhood Hits	997	Target Neighborhood Hits	196	Shared Neighborhood Hits	51
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

PITM1_HUMAN
NC score	0.008711 (rank : 1251)	θ value	1.38821 (rank : 602)
Query Neighborhood Hits	997	Target Neighborhood Hits	129	Shared Neighborhood Hits	40
SwissProt Accessions	O00562, Q6T7X3, Q8TBN3, Q9BZ73	Gene names	PITPNM1, DRES9, NIR2, PITPNM
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 1 (Phosphatidylinositol transfer protein, membrane-associated 1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) (Drosophila retinal degeneration B homolog).

DAF1_MOUSE
NC score	0.008706 (rank : 1252)	θ value	8.99809 (rank : 941)
Query Neighborhood Hits	997	Target Neighborhood Hits	204	Shared Neighborhood Hits	48
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

PHLPP_MOUSE
NC score	0.008387 (rank : 1253)	θ value	0.163984 (rank : 442)
Query Neighborhood Hits	997	Target Neighborhood Hits	394	Shared Neighborhood Hits	46
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

RAD52_HUMAN
NC score	0.008357 (rank : 1254)	θ value	4.03905 (rank : 791)
Query Neighborhood Hits	997	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	P43351, Q13205	Gene names	RAD52
Domain Architecture
Description	DNA repair protein RAD52 homolog.

FOXK1_MOUSE
NC score	0.008269 (rank : 1255)	θ value	2.36792 (rank : 673)
Query Neighborhood Hits	997	Target Neighborhood Hits	215	Shared Neighborhood Hits	54
SwissProt Accessions	P42128, O35939	Gene names	Foxk1, Mnf
Domain Architecture
Description	Forkhead box protein K1 (Myocyte nuclear factor) (MNF).

TSC2_HUMAN
NC score	0.008199 (rank : 1256)	θ value	1.81305 (rank : 646)
Query Neighborhood Hits	997	Target Neighborhood Hits	59	Shared Neighborhood Hits	9
SwissProt Accessions	P49815, O75275, Q8TAZ1	Gene names	TSC2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 protein).

NR4A3_HUMAN
NC score	0.008151 (rank : 1257)	θ value	5.27518 (rank : 835)
Query Neighborhood Hits	997	Target Neighborhood Hits	131	Shared Neighborhood Hits	20
SwissProt Accessions	Q92570, Q12935, Q14979, Q16420, Q4VXA9, Q9UEK2, Q9UEK3	Gene names	NR4A3, CHN, CSMF, MINOR, NOR1, TEC
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Nuclear hormone receptor NOR-1) (Neuron-derived orphan receptor 1) (Mitogen-induced nuclear orphan receptor).

MAGC3_HUMAN
NC score	0.008093 (rank : 1258)	θ value	6.88961 (rank : 895)
Query Neighborhood Hits	997	Target Neighborhood Hits	71	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TD91, Q5JZ43, Q9BZ80	Gene names	MAGEC3, HCA2
Domain Architecture
Description	Melanoma-associated antigen C3 (MAGE-C3 antigen) (Hepatocellular carcinoma-associated antigen 2).

PTCD1_HUMAN
NC score	0.008012 (rank : 1259)	θ value	8.99809 (rank : 970)
Query Neighborhood Hits	997	Target Neighborhood Hits	52	Shared Neighborhood Hits	25
SwissProt Accessions	O75127, Q66K60, Q9UDV2	Gene names	PTCD1, KIAA0632
Domain Architecture	No domain graphic available
Description	Pentatricopeptide repeat protein 1.

DGCR8_MOUSE
NC score	0.007891 (rank : 1260)	θ value	8.99809 (rank : 943)
Query Neighborhood Hits	997	Target Neighborhood Hits	70	Shared Neighborhood Hits	9
SwissProt Accessions	Q9EQM6	Gene names	Dgcr8
Domain Architecture	No domain graphic available
Description	DGCR8 protein (DiGeorge syndrome critical region 8 homolog) (Gy1).

K1849_HUMAN
NC score	0.007890 (rank : 1261)	θ value	5.27518 (rank : 827)
Query Neighborhood Hits	997	Target Neighborhood Hits	220	Shared Neighborhood Hits	35
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

FOXC2_HUMAN
NC score	0.007741 (rank : 1262)	θ value	2.36792 (rank : 672)
Query Neighborhood Hits	997	Target Neighborhood Hits	236	Shared Neighborhood Hits	68
SwissProt Accessions	Q99958	Gene names	FOXC2, FKHL14, MFH1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

HDAC6_HUMAN
NC score	0.007682 (rank : 1263)	θ value	3.0926 (rank : 722)
Query Neighborhood Hits	997	Target Neighborhood Hits	145	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UBN7	Gene names	HDAC6
Domain Architecture
Description	Histone deacetylase 6 (HD6).

ABRA_HUMAN
NC score	0.007570 (rank : 1264)	θ value	8.99809 (rank : 922)
Query Neighborhood Hits	997	Target Neighborhood Hits	52	Shared Neighborhood Hits	20
SwissProt Accessions	Q8N0Z2	Gene names	ABRA
Domain Architecture	No domain graphic available
Description	Actin-binding Rho-activating protein (Striated muscle activator of Rho-dependent signaling) (STARS).

NOS3_HUMAN
NC score	0.007556 (rank : 1265)	θ value	5.27518 (rank : 833)
Query Neighborhood Hits	997	Target Neighborhood Hits	59	Shared Neighborhood Hits	23
SwissProt Accessions	P29474, Q13662, Q14251, Q14434	Gene names	NOS3
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).

RBL2_HUMAN
NC score	0.007116 (rank : 1266)	θ value	2.36792 (rank : 689)
Query Neighborhood Hits	997	Target Neighborhood Hits	44	Shared Neighborhood Hits	12
SwissProt Accessions	Q08999, Q15073, Q16084, Q92812	Gene names	RBL2, RB2
Domain Architecture
Description	Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (PRB2) (P130) (RBR-2).

ABR_HUMAN
NC score	0.007112 (rank : 1267)	θ value	4.03905 (rank : 753)
Query Neighborhood Hits	997	Target Neighborhood Hits	166	Shared Neighborhood Hits	29
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

PDLI5_HUMAN
NC score	0.007097 (rank : 1268)	θ value	3.0926 (rank : 733)
Query Neighborhood Hits	997	Target Neighborhood Hits	322	Shared Neighborhood Hits	46
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

ZEP1_MOUSE
NC score	0.007045 (rank : 1269)	θ value	5.27518 (rank : 856)
Query Neighborhood Hits	997	Target Neighborhood Hits	1063	Shared Neighborhood Hits	130
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

K0056_HUMAN
NC score	0.006981 (rank : 1270)	θ value	6.88961 (rank : 891)
Query Neighborhood Hits	997	Target Neighborhood Hits	107	Shared Neighborhood Hits	22
SwissProt Accessions	P42695	Gene names	KIAA0056
Domain Architecture	No domain graphic available
Description	Protein KIAA0056.

MMP15_MOUSE
NC score	0.006976 (rank : 1271)	θ value	0.62314 (rank : 524)
Query Neighborhood Hits	997	Target Neighborhood Hits	102	Shared Neighborhood Hits	38
SwissProt Accessions	O54732	Gene names	Mmp15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP).

REXO4_MOUSE
NC score	0.006819 (rank : 1272)	θ value	5.27518 (rank : 839)
Query Neighborhood Hits	997	Target Neighborhood Hits	42	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PAQ4, Q3UU17, Q8C524	Gene names	Rexo4, Gm111, Pmc2, Xpmc2h
Domain Architecture	No domain graphic available
Description	RNA exonuclease 4 (EC 3.1.-.-) (Exonuclease XPMC2) (Prevents mitotic catastrophe 2 protein homolog).

ARHGG_MOUSE
NC score	0.006776 (rank : 1273)	θ value	6.88961 (rank : 864)
Query Neighborhood Hits	997	Target Neighborhood Hits	152	Shared Neighborhood Hits	36
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

BTBD2_HUMAN
NC score	0.006751 (rank : 1274)	θ value	8.99809 (rank : 931)
Query Neighborhood Hits	997	Target Neighborhood Hits	161	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BX70, O60418, O75248, Q7Z5W0, Q96SX8, Q9NPS1, Q9NX81	Gene names	BTBD2
Domain Architecture
Description	BTB/POZ domain-containing protein 2.

FOXP4_HUMAN
NC score	0.006540 (rank : 1275)	θ value	4.03905 (rank : 778)
Query Neighborhood Hits	997	Target Neighborhood Hits	246	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IVH2, Q96E19	Gene names	FOXP4, FKHLA
Domain Architecture
Description	Forkhead box protein P4 (Fork head-related protein-like A).

RBBP5_HUMAN
NC score	0.006502 (rank : 1276)	θ value	1.38821 (rank : 606)
Query Neighborhood Hits	997	Target Neighborhood Hits	372	Shared Neighborhood Hits	26
SwissProt Accessions	Q15291	Gene names	RBBP5, RBQ3
Domain Architecture
Description	Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3).

TAF9B_MOUSE
NC score	0.006490 (rank : 1277)	θ value	5.27518 (rank : 848)
Query Neighborhood Hits	997	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	Q6NZA9, Q3UXZ3, Q3V2M4, Q80WW6	Gene names	Taf9b, Taf9l
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 9B (Transcription initiation factor TFIID subunit 9-like protein) (Transcription- associated factor TAFII31L).

MYBPH_HUMAN
NC score	0.006371 (rank : 1278)	θ value	6.88961 (rank : 897)
Query Neighborhood Hits	997	Target Neighborhood Hits	256	Shared Neighborhood Hits	36
SwissProt Accessions	Q13203, Q16886, Q86YC5	Gene names	MYBPH
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

PTN22_MOUSE
NC score	0.006289 (rank : 1279)	θ value	5.27518 (rank : 837)
Query Neighborhood Hits	997	Target Neighborhood Hits	179	Shared Neighborhood Hits	44
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

UBP43_HUMAN
NC score	0.006229 (rank : 1280)	θ value	5.27518 (rank : 854)
Query Neighborhood Hits	997	Target Neighborhood Hits	144	Shared Neighborhood Hits	34
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

SMBP2_HUMAN
NC score	0.006207 (rank : 1281)	θ value	8.99809 (rank : 975)
Query Neighborhood Hits	997	Target Neighborhood Hits	107	Shared Neighborhood Hits	27
SwissProt Accessions	P38935, Q00443, Q14177	Gene names	IGHMBP2, SMBP2, SMUBP2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Glial factor 1) (GF-1).

MMP15_HUMAN
NC score	0.005911 (rank : 1282)	θ value	1.81305 (rank : 629)
Query Neighborhood Hits	997	Target Neighborhood Hits	95	Shared Neighborhood Hits	31
SwissProt Accessions	P51511, Q14111	Gene names	MMP15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP) (SMCP- 2).

FA84B_HUMAN
NC score	0.005904 (rank : 1283)	θ value	5.27518 (rank : 819)
Query Neighborhood Hits	997	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q96KN1	Gene names	FAM84B, NSE2
Domain Architecture	No domain graphic available
Description	Protein FAM84B (Protein NSE2) (Breast cancer membrane protein 101).

ERCC1_HUMAN
NC score	0.005784 (rank : 1284)	θ value	8.99809 (rank : 946)
Query Neighborhood Hits	997	Target Neighborhood Hits	34	Shared Neighborhood Hits	13
SwissProt Accessions	P07992	Gene names	ERCC1
Domain Architecture
Description	DNA excision repair protein ERCC-1.

SSH1_HUMAN
NC score	0.005778 (rank : 1285)	θ value	8.99809 (rank : 983)
Query Neighborhood Hits	997	Target Neighborhood Hits	164	Shared Neighborhood Hits	46
SwissProt Accessions	Q8WYL5, Q6P6C0, Q8N9A7, Q8WYL3, Q8WYL4, Q9P2P8	Gene names	SSH1, KIAA1298, SSH1L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (hSSH-1L).

HXB3_HUMAN
NC score	0.005676 (rank : 1286)	θ value	0.62314 (rank : 522)
Query Neighborhood Hits	997	Target Neighborhood Hits	559	Shared Neighborhood Hits	113
SwissProt Accessions	P14651, O95615, P17484	Gene names	HOXB3, HOX2G
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2G) (Hox-2.7).

BOC_HUMAN
NC score	0.005665 (rank : 1287)	θ value	5.27518 (rank : 809)
Query Neighborhood Hits	997	Target Neighborhood Hits	543	Shared Neighborhood Hits	83
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

NOS3_MOUSE
NC score	0.005567 (rank : 1288)	θ value	5.27518 (rank : 834)
Query Neighborhood Hits	997	Target Neighborhood Hits	63	Shared Neighborhood Hits	23
SwissProt Accessions	P70313, O55056	Gene names	Nos3, Ecnos
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).

URP2_MOUSE
NC score	0.005398 (rank : 1289)	θ value	1.81305 (rank : 648)
Query Neighborhood Hits	997	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K1B8	Gene names	Urp2, Kind3
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3).

PDE3A_MOUSE
NC score	0.005116 (rank : 1290)	θ value	3.0926 (rank : 732)
Query Neighborhood Hits	997	Target Neighborhood Hits	115	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z0X4	Gene names	Pde3a
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

INSI1_MOUSE
NC score	0.004628 (rank : 1291)	θ value	8.99809 (rank : 957)
Query Neighborhood Hits	997	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGI3, Q3UAX9	Gene names	Insig1
Domain Architecture	No domain graphic available
Description	Insulin-induced gene 1 protein (INSIG-1).

ERR1_HUMAN
NC score	0.004525 (rank : 1292)	θ value	4.03905 (rank : 776)
Query Neighborhood Hits	997	Target Neighborhood Hits	157	Shared Neighborhood Hits	35
SwissProt Accessions	P11474, Q14514	Gene names	ESRRA, ERR1, ESRL1, NR3B1
Domain Architecture
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR- alpha) (Estrogen receptor-like 1).

COT2_HUMAN
NC score	0.004378 (rank : 1293)	θ value	0.62314 (rank : 518)
Query Neighborhood Hits	997	Target Neighborhood Hits	135	Shared Neighborhood Hits	26
SwissProt Accessions	P24468, Q03754	Gene names	NR2F2, ARP1, TFCOUP2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

COT2_MOUSE
NC score	0.004378 (rank : 1294)	θ value	0.62314 (rank : 519)
Query Neighborhood Hits	997	Target Neighborhood Hits	135	Shared Neighborhood Hits	26
SwissProt Accessions	P43135	Gene names	Nr2f2, Aporp1, Arp-1, Arp1, Tfcoup2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

NALP1_HUMAN
NC score	0.004211 (rank : 1295)	θ value	4.03905 (rank : 787)
Query Neighborhood Hits	997	Target Neighborhood Hits	138	Shared Neighborhood Hits	28
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

FOXJ3_HUMAN
NC score	0.004179 (rank : 1296)	θ value	5.27518 (rank : 822)
Query Neighborhood Hits	997	Target Neighborhood Hits	177	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UPW0, Q9NSS7	Gene names	FOXJ3, KIAA1041
Domain Architecture
Description	Forkhead box protein J3.

AAKG2_HUMAN
NC score	0.004177 (rank : 1297)	θ value	6.88961 (rank : 860)
Query Neighborhood Hits	997	Target Neighborhood Hits	56	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UGJ0, Q53Y07, Q6NUI0, Q75MP4, Q9NUZ9, Q9UDN8, Q9ULX8	Gene names	PRKAG2
Domain Architecture
Description	5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma-2 chain) (AMPK gamma2) (H91620p).

RARG1_MOUSE
NC score	0.004075 (rank : 1298)	θ value	1.06291 (rank : 575)
Query Neighborhood Hits	997	Target Neighborhood Hits	113	Shared Neighborhood Hits	11
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

RARG2_MOUSE
NC score	0.004060 (rank : 1299)	θ value	1.06291 (rank : 576)
Query Neighborhood Hits	997	Target Neighborhood Hits	114	Shared Neighborhood Hits	11
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

QSCN6_MOUSE
NC score	0.003702 (rank : 1300)	θ value	4.03905 (rank : 790)
Query Neighborhood Hits	997	Target Neighborhood Hits	62	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BND5, Q3TDY9, Q3TE19, Q3TR29, Q3UEL4, Q8K041, Q9DBL6	Gene names	Qscn6, Sox
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 1 precursor (EC 1.8.3.2) (Quiescin Q6) (Skin sulfhydryl oxidase) (mSOx).

DLG1_HUMAN
NC score	0.003669 (rank : 1301)	θ value	2.36792 (rank : 668)
Query Neighborhood Hits	997	Target Neighborhood Hits	290	Shared Neighborhood Hits	41
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

ZO2_MOUSE
NC score	0.003473 (rank : 1302)	θ value	8.99809 (rank : 997)
Query Neighborhood Hits	997	Target Neighborhood Hits	296	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

H6ST3_MOUSE
NC score	0.003307 (rank : 1303)	θ value	8.99809 (rank : 952)
Query Neighborhood Hits	997	Target Neighborhood Hits	46	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QYK4	Gene names	Hs6st3
Domain Architecture	No domain graphic available
Description	Heparan-sulfate 6-O-sulfotransferase 3 (EC 2.8.2.-) (HS6ST-3) (mHS6ST- 3).

PTN14_MOUSE
NC score	0.003306 (rank : 1304)	θ value	1.38821 (rank : 604)
Query Neighborhood Hits	997	Target Neighborhood Hits	142	Shared Neighborhood Hits	12
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

WRIP1_MOUSE
NC score	0.003231 (rank : 1305)	θ value	8.99809 (rank : 996)
Query Neighborhood Hits	997	Target Neighborhood Hits	93	Shared Neighborhood Hits	10
SwissProt Accessions	Q91XU0, Q3TCT7, Q6PDF0, Q8BUW5, Q8BWP6, Q8BY55, Q921W3, Q9EQL3	Gene names	Wrnip1, Whip
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

PTN14_HUMAN
NC score	0.003069 (rank : 1306)	θ value	1.38821 (rank : 603)
Query Neighborhood Hits	997	Target Neighborhood Hits	163	Shared Neighborhood Hits	15
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

TSH3_MOUSE
NC score	0.002881 (rank : 1307)	θ value	6.88961 (rank : 912)
Query Neighborhood Hits	997	Target Neighborhood Hits	590	Shared Neighborhood Hits	46
SwissProt Accessions	Q8CGV9, Q5DTX4	Gene names	Tshz3, Kiaa1474, Tsh3, Zfp537, Znf537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

PTPRN_MOUSE
NC score	0.002835 (rank : 1308)	θ value	6.88961 (rank : 903)
Query Neighborhood Hits	997	Target Neighborhood Hits	240	Shared Neighborhood Hits	68
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

TTLL5_HUMAN
NC score	0.002798 (rank : 1309)	θ value	8.99809 (rank : 993)
Query Neighborhood Hits	997	Target Neighborhood Hits	141	Shared Neighborhood Hits	21
SwissProt Accessions	Q6EMB2, Q9P1V5, Q9UPZ4	Gene names	TTLL5, KIAA0998, STAMP
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5 (SRC1 and TIF2-associated modulatory protein).

RREB1_HUMAN
NC score	0.002613 (rank : 1310)	θ value	5.27518 (rank : 841)
Query Neighborhood Hits	997	Target Neighborhood Hits	879	Shared Neighborhood Hits	97
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

TBX21_HUMAN
NC score	0.001930 (rank : 1311)	θ value	8.99809 (rank : 987)
Query Neighborhood Hits	997	Target Neighborhood Hits	146	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UL17	Gene names	TBX21, TBET, TBLYM
Domain Architecture
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

TBX18_HUMAN
NC score	0.001864 (rank : 1312)	θ value	5.27518 (rank : 849)
Query Neighborhood Hits	997	Target Neighborhood Hits	148	Shared Neighborhood Hits	38
SwissProt Accessions	O95935, Q7Z6U4, Q9UJI6	Gene names	TBX18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

MARE1_HUMAN
NC score	0.001719 (rank : 1313)	θ value	8.99809 (rank : 962)
Query Neighborhood Hits	997	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q15691	Gene names	MAPRE1
Domain Architecture
Description	Microtubule-associated protein RP/EB family member 1 (APC-binding protein EB1) (End-binding protein 1) (EB1).

ZN438_HUMAN
NC score	0.000275 (rank : 1314)	θ value	3.0926 (rank : 749)
Query Neighborhood Hits	997	Target Neighborhood Hits	906	Shared Neighborhood Hits	101
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

PIWL3_HUMAN
NC score	0.000068 (rank : 1315)	θ value	8.99809 (rank : 968)
Query Neighborhood Hits	997	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z3Z3	Gene names	PIWIL3
Domain Architecture	No domain graphic available
Description	Piwi-like protein 3.

MFRN2_MOUSE
NC score	-0.000325 (rank : 1316)	θ value	4.03905 (rank : 784)
Query Neighborhood Hits	997	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R0Z5, Q8K4J8, Q8K4J9, Q8R578	Gene names	Slc25a28, Mfrn2
Domain Architecture	No domain graphic available
Description	Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute carrier family 25 member 28) (Mitochondrial RNA-splicing protein 3/4 homolog) (MRS3/4).

SNTB2_HUMAN
NC score	-0.000411 (rank : 1317)	θ value	8.99809 (rank : 979)
Query Neighborhood Hits	997	Target Neighborhood Hits	180	Shared Neighborhood Hits	17
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

ATL2_MOUSE
NC score	-0.001172 (rank : 1318)	θ value	8.99809 (rank : 928)
Query Neighborhood Hits	997	Target Neighborhood Hits	137	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

ZN447_HUMAN
NC score	-0.001812 (rank : 1319)	θ value	5.27518 (rank : 858)
Query Neighborhood Hits	997	Target Neighborhood Hits	899	Shared Neighborhood Hits	87
SwissProt Accessions	Q8TBC5, Q9BRK7, Q9H9A0	Gene names	ZNF447
Domain Architecture	No domain graphic available
Description	Zinc finger protein 447.

RBM19_HUMAN
NC score	-0.002032 (rank : 1320)	θ value	2.36792 (rank : 690)
Query Neighborhood Hits	997	Target Neighborhood Hits	331	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y4C8, Q9BPY6, Q9UFN5	Gene names	RBM19, KIAA0682
Domain Architecture
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

CDC20_HUMAN
NC score	-0.003872 (rank : 1321)	θ value	8.99809 (rank : 933)
Query Neighborhood Hits	997	Target Neighborhood Hits	329	Shared Neighborhood Hits	29
SwissProt Accessions	Q12834, Q9BW56, Q9UQI9	Gene names	CDC20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC).

KLF17_HUMAN
NC score	-0.004067 (rank : 1322)	θ value	4.03905 (rank : 781)
Query Neighborhood Hits	997	Target Neighborhood Hits	882	Shared Neighborhood Hits	126
SwissProt Accessions	Q5JT82, Q86VQ7, Q8N805	Gene names	KLF17, ZNF393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393).

ZBTB3_HUMAN
NC score	-0.004485 (rank : 1323)	θ value	6.88961 (rank : 918)
Query Neighborhood Hits	997	Target Neighborhood Hits	910	Shared Neighborhood Hits	74
SwissProt Accessions	Q9H5J0	Gene names	ZBTB3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

EGR4_HUMAN
NC score	-0.005246 (rank : 1324)	θ value	6.88961 (rank : 882)
Query Neighborhood Hits	997	Target Neighborhood Hits	939	Shared Neighborhood Hits	129
SwissProt Accessions	Q05215	Gene names	EGR4
Domain Architecture
Description	Early growth response protein 4 (EGR-4) (AT133).

PCDH7_HUMAN
NC score	-0.005257 (rank : 1325)	θ value	1.06291 (rank : 570)
Query Neighborhood Hits	997	Target Neighborhood Hits	175	Shared Neighborhood Hits	9
SwissProt Accessions	O60245, O60246, O60247	Gene names	PCDH7, BHPCDH
Domain Architecture
Description	Protocadherin-7 precursor (Brain-heart protocadherin) (BH-Pcdh).

HXB9_MOUSE
NC score	-0.006367 (rank : 1326)	θ value	5.27518 (rank : 825)
Query Neighborhood Hits	997	Target Neighborhood Hits	344	Shared Neighborhood Hits	20
SwissProt Accessions	P20615	Gene names	Hoxb9, Hox-2.5, Hoxb-9
Domain Architecture
Description	Homeobox protein Hox-B9 (Hox-2.5).

MTR1L_HUMAN
NC score	-0.006399 (rank : 1327)	θ value	0.279714 (rank : 469)
Query Neighborhood Hits	997	Target Neighborhood Hits	1180	Shared Neighborhood Hits	97
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

HIC1_HUMAN
NC score	-0.006459 (rank : 1328)	θ value	0.00869519 (rank : 334)
Query Neighborhood Hits	997	Target Neighborhood Hits	838	Shared Neighborhood Hits	66
SwissProt Accessions	Q14526	Gene names	HIC1, ZBTB29
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1) (Zinc finger and BTB domain-containing protein 29).

HIC1_MOUSE
NC score	-0.007047 (rank : 1329)	θ value	1.81305 (rank : 621)
Query Neighborhood Hits	997	Target Neighborhood Hits	863	Shared Neighborhood Hits	74
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).

ZN341_HUMAN
NC score	-0.007465 (rank : 1330)	θ value	1.06291 (rank : 582)
Query Neighborhood Hits	997	Target Neighborhood Hits	803	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BYN7, Q5JXM8, Q96ST5	Gene names	ZNF341
Domain Architecture	No domain graphic available
Description	Zinc finger protein 341.

ZN142_HUMAN
NC score	-0.008024 (rank : 1331)	θ value	3.0926 (rank : 748)
Query Neighborhood Hits	997	Target Neighborhood Hits	1007	Shared Neighborhood Hits	134
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).

SP5_HUMAN
NC score	-0.008368 (rank : 1332)	θ value	1.81305 (rank : 641)
Query Neighborhood Hits	997	Target Neighborhood Hits	832	Shared Neighborhood Hits	85
SwissProt Accessions	Q6BEB4	Gene names	SP5
Domain Architecture	No domain graphic available
Description	Transcription factor Sp5.

ZSCA5_HUMAN
NC score	-0.010269 (rank : 1333)	θ value	5.27518 (rank : 859)
Query Neighborhood Hits	997	Target Neighborhood Hits	862	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BUG6	Gene names	ZSCAN5, ZNF495
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 5 (Zinc finger protein 495).

ZN174_HUMAN
NC score	-0.010407 (rank : 1334)	θ value	0.0961366 (rank : 415)
Query Neighborhood Hits	997	Target Neighborhood Hits	744	Shared Neighborhood Hits	44
SwissProt Accessions	Q15697, Q9BQ34	Gene names	ZNF174, ZSCAN8
Domain Architecture
Description	Zinc finger protein 174 (AW-1) (Zinc finger and SCAN domain-containing protein 8).

OVOL2_HUMAN
NC score	-0.010511 (rank : 1335)	θ value	0.47712 (rank : 504)
Query Neighborhood Hits	997	Target Neighborhood Hits	715	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BRP0, Q5T8B4, Q9BX22, Q9HA54, Q9Y4M0	Gene names	OVOL2, ZNF339
Domain Architecture	No domain graphic available
Description	Transcription factor Ovo-like 2 (hOvo2) (Zinc finger protein 339).

BCL6_MOUSE
NC score	-0.011375 (rank : 1336)	θ value	3.0926 (rank : 708)
Query Neighborhood Hits	997	Target Neighborhood Hits	913	Shared Neighborhood Hits	74
SwissProt Accessions	P41183, Q61065	Gene names	Bcl6, Bcl-6
Domain Architecture
Description	B-cell lymphoma 6 protein homolog.

ZN746_HUMAN
NC score	-0.011392 (rank : 1337)	θ value	1.38821 (rank : 609)
Query Neighborhood Hits	997	Target Neighborhood Hits	745	Shared Neighborhood Hits	50
SwissProt Accessions	Q6NUN9	Gene names	ZNF746
Domain Architecture	No domain graphic available
Description	Zinc finger protein 746.

ZBT47_HUMAN
NC score	-0.013494 (rank : 1338)	θ value	3.0926 (rank : 746)
Query Neighborhood Hits	997	Target Neighborhood Hits	737	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UFB7, Q8WTY8, Q9ULN0	Gene names	ZBTB47, KIAA1190, ZNF651
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 47 (Zinc finger protein 651).

ZN213_HUMAN
NC score	-0.013495 (rank : 1339)	θ value	5.27518 (rank : 857)
Query Neighborhood Hits	997	Target Neighborhood Hits	755	Shared Neighborhood Hits	41
SwissProt Accessions	O14771, Q96IS1	Gene names	ZNF213
Domain Architecture
Description	Zinc finger protein 213 (Putative transcription factor CR53).