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Network neighborhood for query Sequence : NOTC2_HUMAN

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NOTC2_HUMAN
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NOTC1_HUMAN
θ value	0 (rank : 1)	NC score	0.984886 (rank : 3)
Query Neighborhood Hits	1113	Target Neighborhood Hits	906	Shared Neighborhood Hits	774
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC1_MOUSE
θ value	0 (rank : 2)	NC score	0.980504 (rank : 6)
Query Neighborhood Hits	1113	Target Neighborhood Hits	916	Shared Neighborhood Hits	776
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1113	Shared Neighborhood Hits	1113
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
θ value	0 (rank : 4)	NC score	0.992845 (rank : 2)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1069	Shared Neighborhood Hits	917
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC3_HUMAN
θ value	0 (rank : 5)	NC score	0.982953 (rank : 5)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1062	Shared Neighborhood Hits	816
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
θ value	0 (rank : 6)	NC score	0.983610 (rank : 4)
Query Neighborhood Hits	1113	Target Neighborhood Hits	975	Shared Neighborhood Hits	790
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC4_HUMAN
θ value	0 (rank : 7)	NC score	0.975976 (rank : 7)
Query Neighborhood Hits	1113	Target Neighborhood Hits	905	Shared Neighborhood Hits	778
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC4_MOUSE
θ value	0 (rank : 8)	NC score	0.974904 (rank : 8)
Query Neighborhood Hits	1113	Target Neighborhood Hits	872	Shared Neighborhood Hits	755
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

JAG1_HUMAN
θ value	3.06238e-149 (rank : 9)	NC score	0.874016 (rank : 9)
Query Neighborhood Hits	1113	Target Neighborhood Hits	514	Shared Neighborhood Hits	447
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
θ value	1.51984e-148 (rank : 10)	NC score	0.873939 (rank : 10)
Query Neighborhood Hits	1113	Target Neighborhood Hits	518	Shared Neighborhood Hits	446
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

FBN1_HUMAN
θ value	2.19465e-147 (rank : 11)	NC score	0.819209 (rank : 33)
Query Neighborhood Hits	1113	Target Neighborhood Hits	557	Shared Neighborhood Hits	447
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

JAG2_MOUSE
θ value	6.38546e-147 (rank : 12)	NC score	0.872406 (rank : 12)
Query Neighborhood Hits	1113	Target Neighborhood Hits	504	Shared Neighborhood Hits	439
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

FBN1_MOUSE
θ value	1.57279e-145 (rank : 13)	NC score	0.820292 (rank : 32)
Query Neighborhood Hits	1113	Target Neighborhood Hits	563	Shared Neighborhood Hits	455
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

JAG2_HUMAN
θ value	4.57613e-145 (rank : 14)	NC score	0.872644 (rank : 11)
Query Neighborhood Hits	1113	Target Neighborhood Hits	491	Shared Neighborhood Hits	439
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

FBN2_MOUSE
θ value	3.62588e-142 (rank : 15)	NC score	0.820471 (rank : 31)
Query Neighborhood Hits	1113	Target Neighborhood Hits	549	Shared Neighborhood Hits	447
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
θ value	8.93083e-141 (rank : 16)	NC score	0.820949 (rank : 29)
Query Neighborhood Hits	1113	Target Neighborhood Hits	543	Shared Neighborhood Hits	430
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FBN2_HUMAN
θ value	1.42583e-138 (rank : 17)	NC score	0.820654 (rank : 30)
Query Neighborhood Hits	1113	Target Neighborhood Hits	560	Shared Neighborhood Hits	450
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

CRUM1_HUMAN
θ value	5.11853e-104 (rank : 18)	NC score	0.854870 (rank : 16)
Query Neighborhood Hits	1113	Target Neighborhood Hits	457	Shared Neighborhood Hits	419
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM1_MOUSE
θ value	7.39111e-103 (rank : 19)	NC score	0.855426 (rank : 15)
Query Neighborhood Hits	1113	Target Neighborhood Hits	444	Shared Neighborhood Hits	411
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

MEGF6_HUMAN
θ value	3.1125e-93 (rank : 20)	NC score	0.827389 (rank : 28)
Query Neighborhood Hits	1113	Target Neighborhood Hits	671	Shared Neighborhood Hits	487
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

CRUM2_HUMAN
θ value	4.49445e-92 (rank : 21)	NC score	0.857024 (rank : 14)
Query Neighborhood Hits	1113	Target Neighborhood Hits	453	Shared Neighborhood Hits	416
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

DNER_HUMAN
θ value	1.10959e-82 (rank : 22)	NC score	0.857171 (rank : 13)
Query Neighborhood Hits	1113	Target Neighborhood Hits	460	Shared Neighborhood Hits	418
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DNER_MOUSE
θ value	1.49966e-79 (rank : 23)	NC score	0.854777 (rank : 17)
Query Neighborhood Hits	1113	Target Neighborhood Hits	413	Shared Neighborhood Hits	391
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

DLL1_HUMAN
θ value	2.31901e-72 (rank : 24)	NC score	0.850050 (rank : 19)
Query Neighborhood Hits	1113	Target Neighborhood Hits	455	Shared Neighborhood Hits	417
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DLL1_MOUSE
θ value	1.15091e-71 (rank : 25)	NC score	0.853059 (rank : 18)
Query Neighborhood Hits	1113	Target Neighborhood Hits	456	Shared Neighborhood Hits	428
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

DLL4_MOUSE
θ value	1.15091e-71 (rank : 26)	NC score	0.845949 (rank : 20)
Query Neighborhood Hits	1113	Target Neighborhood Hits	440	Shared Neighborhood Hits	404
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

LTBP2_MOUSE
θ value	7.45998e-71 (rank : 27)	NC score	0.801998 (rank : 35)
Query Neighborhood Hits	1113	Target Neighborhood Hits	617	Shared Neighborhood Hits	444
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP2_HUMAN
θ value	4.83544e-70 (rank : 28)	NC score	0.801842 (rank : 36)
Query Neighborhood Hits	1113	Target Neighborhood Hits	552	Shared Neighborhood Hits	425
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

DLL4_HUMAN
θ value	1.5555e-68 (rank : 29)	NC score	0.845238 (rank : 21)
Query Neighborhood Hits	1113	Target Neighborhood Hits	435	Shared Neighborhood Hits	399
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

LTBP4_MOUSE
θ value	1.5555e-68 (rank : 30)	NC score	0.815568 (rank : 34)
Query Neighborhood Hits	1113	Target Neighborhood Hits	607	Shared Neighborhood Hits	416
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

TENX_HUMAN
θ value	1.90147e-66 (rank : 31)	NC score	0.632445 (rank : 103)
Query Neighborhood Hits	1113	Target Neighborhood Hits	789	Shared Neighborhood Hits	436
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

LTB1L_HUMAN
θ value	1.07972e-61 (rank : 32)	NC score	0.780966 (rank : 39)
Query Neighborhood Hits	1113	Target Neighborhood Hits	553	Shared Neighborhood Hits	427
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	1.07972e-61 (rank : 33)	NC score	0.779691 (rank : 42)
Query Neighborhood Hits	1113	Target Neighborhood Hits	502	Shared Neighborhood Hits	408
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_MOUSE
θ value	1.41016e-61 (rank : 34)	NC score	0.780617 (rank : 40)
Query Neighborhood Hits	1113	Target Neighborhood Hits	514	Shared Neighborhood Hits	424
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	1.41016e-61 (rank : 35)	NC score	0.779810 (rank : 41)
Query Neighborhood Hits	1113	Target Neighborhood Hits	479	Shared Neighborhood Hits	400
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

TENA_HUMAN
θ value	1.55911e-60 (rank : 36)	NC score	0.634630 (rank : 100)
Query Neighborhood Hits	1113	Target Neighborhood Hits	631	Shared Neighborhood Hits	401
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENA_MOUSE
θ value	2.48917e-58 (rank : 37)	NC score	0.629041 (rank : 106)
Query Neighborhood Hits	1113	Target Neighborhood Hits	596	Shared Neighborhood Hits	390
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

SLIT1_HUMAN
θ value	2.32979e-56 (rank : 38)	NC score	0.609739 (rank : 110)
Query Neighborhood Hits	1113	Target Neighborhood Hits	700	Shared Neighborhood Hits	390
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

LTBP3_HUMAN
θ value	3.974e-56 (rank : 39)	NC score	0.792924 (rank : 37)
Query Neighborhood Hits	1113	Target Neighborhood Hits	502	Shared Neighborhood Hits	400
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

SLIT2_HUMAN
θ value	3.974e-56 (rank : 40)	NC score	0.602428 (rank : 114)
Query Neighborhood Hits	1113	Target Neighborhood Hits	708	Shared Neighborhood Hits	400
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT1_MOUSE
θ value	1.51013e-55 (rank : 41)	NC score	0.611357 (rank : 109)
Query Neighborhood Hits	1113	Target Neighborhood Hits	715	Shared Neighborhood Hits	395
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

SLIT2_MOUSE
θ value	1.51013e-55 (rank : 42)	NC score	0.597301 (rank : 118)
Query Neighborhood Hits	1113	Target Neighborhood Hits	684	Shared Neighborhood Hits	379
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT3_HUMAN
θ value	2.57589e-55 (rank : 43)	NC score	0.582337 (rank : 124)
Query Neighborhood Hits	1113	Target Neighborhood Hits	682	Shared Neighborhood Hits	373
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

SLIT3_MOUSE
θ value	2.57589e-55 (rank : 44)	NC score	0.589210 (rank : 120)
Query Neighborhood Hits	1113	Target Neighborhood Hits	700	Shared Neighborhood Hits	390
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

EGFL9_MOUSE
θ value	1.08223e-53 (rank : 45)	NC score	0.834171 (rank : 23)
Query Neighborhood Hits	1113	Target Neighborhood Hits	379	Shared Neighborhood Hits	360
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

CUBN_HUMAN
θ value	1.41344e-53 (rank : 46)	NC score	0.695930 (rank : 76)
Query Neighborhood Hits	1113	Target Neighborhood Hits	482	Shared Neighborhood Hits	387
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

EGFL9_HUMAN
θ value	7.01481e-53 (rank : 47)	NC score	0.834871 (rank : 22)
Query Neighborhood Hits	1113	Target Neighborhood Hits	365	Shared Neighborhood Hits	351
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

LTBP3_MOUSE
θ value	2.041e-52 (rank : 48)	NC score	0.788453 (rank : 38)
Query Neighborhood Hits	1113	Target Neighborhood Hits	475	Shared Neighborhood Hits	396
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

CUBN_MOUSE
θ value	2.25659e-51 (rank : 49)	NC score	0.700379 (rank : 74)
Query Neighborhood Hits	1113	Target Neighborhood Hits	477	Shared Neighborhood Hits	376
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

DLL3_MOUSE
θ value	1.23823e-49 (rank : 50)	NC score	0.831651 (rank : 25)
Query Neighborhood Hits	1113	Target Neighborhood Hits	399	Shared Neighborhood Hits	366
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

DLL3_HUMAN
θ value	3.60269e-49 (rank : 51)	NC score	0.831443 (rank : 27)
Query Neighborhood Hits	1113	Target Neighborhood Hits	419	Shared Neighborhood Hits	379
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

FBLN2_HUMAN
θ value	5.7518e-47 (rank : 52)	NC score	0.755665 (rank : 48)
Query Neighborhood Hits	1113	Target Neighborhood Hits	392	Shared Neighborhood Hits	310
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

DLK_HUMAN
θ value	9.50281e-42 (rank : 53)	NC score	0.833368 (rank : 24)
Query Neighborhood Hits	1113	Target Neighborhood Hits	401	Shared Neighborhood Hits	378
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

FBLN2_MOUSE
θ value	3.05695e-40 (rank : 54)	NC score	0.751159 (rank : 49)
Query Neighborhood Hits	1113	Target Neighborhood Hits	505	Shared Neighborhood Hits	350
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

DLK_MOUSE
θ value	6.81017e-40 (rank : 55)	NC score	0.831647 (rank : 26)
Query Neighborhood Hits	1113	Target Neighborhood Hits	374	Shared Neighborhood Hits	361
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

FBLN1_HUMAN
θ value	6.37413e-38 (rank : 56)	NC score	0.741085 (rank : 51)
Query Neighborhood Hits	1113	Target Neighborhood Hits	324	Shared Neighborhood Hits	298
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

NELL2_HUMAN
θ value	3.86705e-35 (rank : 57)	NC score	0.776499 (rank : 44)
Query Neighborhood Hits	1113	Target Neighborhood Hits	449	Shared Neighborhood Hits	387
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

FBLN1_MOUSE
θ value	1.46948e-34 (rank : 58)	NC score	0.739696 (rank : 52)
Query Neighborhood Hits	1113	Target Neighborhood Hits	329	Shared Neighborhood Hits	296
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

NELL2_MOUSE
θ value	1.46948e-34 (rank : 59)	NC score	0.775525 (rank : 45)
Query Neighborhood Hits	1113	Target Neighborhood Hits	436	Shared Neighborhood Hits	383
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

HMCN1_HUMAN
θ value	5.584e-34 (rank : 60)	NC score	0.446015 (rank : 211)
Query Neighborhood Hits	1113	Target Neighborhood Hits	983	Shared Neighborhood Hits	348
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

FATH_HUMAN
θ value	6.82597e-32 (rank : 61)	NC score	0.425414 (rank : 269)
Query Neighborhood Hits	1113	Target Neighborhood Hits	570	Shared Neighborhood Hits	353
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

SREC_HUMAN
θ value	5.77852e-31 (rank : 62)	NC score	0.746791 (rank : 50)
Query Neighborhood Hits	1113	Target Neighborhood Hits	645	Shared Neighborhood Hits	431
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

SCUB3_MOUSE
θ value	2.19584e-30 (rank : 63)	NC score	0.726660 (rank : 58)
Query Neighborhood Hits	1113	Target Neighborhood Hits	442	Shared Neighborhood Hits	314
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_HUMAN
θ value	2.86786e-30 (rank : 64)	NC score	0.727245 (rank : 57)
Query Neighborhood Hits	1113	Target Neighborhood Hits	428	Shared Neighborhood Hits	307
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

NELL1_HUMAN
θ value	1.85889e-29 (rank : 65)	NC score	0.777825 (rank : 43)
Query Neighborhood Hits	1113	Target Neighborhood Hits	451	Shared Neighborhood Hits	384
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

LRP1_HUMAN
θ value	4.14116e-29 (rank : 66)	NC score	0.637417 (rank : 97)
Query Neighborhood Hits	1113	Target Neighborhood Hits	617	Shared Neighborhood Hits	460
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

EMR1_MOUSE
θ value	9.2256e-29 (rank : 67)	NC score	0.600493 (rank : 116)
Query Neighborhood Hits	1113	Target Neighborhood Hits	349	Shared Neighborhood Hits	262
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

MATN2_HUMAN
θ value	1.57365e-28 (rank : 68)	NC score	0.657466 (rank : 88)
Query Neighborhood Hits	1113	Target Neighborhood Hits	365	Shared Neighborhood Hits	276
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

FBLN4_HUMAN
θ value	1.33217e-27 (rank : 69)	NC score	0.718618 (rank : 60)
Query Neighborhood Hits	1113	Target Neighborhood Hits	278	Shared Neighborhood Hits	254
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN5_MOUSE
θ value	2.27234e-27 (rank : 70)	NC score	0.711279 (rank : 70)
Query Neighborhood Hits	1113	Target Neighborhood Hits	317	Shared Neighborhood Hits	278
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

MATN2_MOUSE
θ value	2.96777e-27 (rank : 71)	NC score	0.645583 (rank : 95)
Query Neighborhood Hits	1113	Target Neighborhood Hits	356	Shared Neighborhood Hits	275
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

LRP1B_HUMAN
θ value	5.06226e-27 (rank : 72)	NC score	0.634067 (rank : 101)
Query Neighborhood Hits	1113	Target Neighborhood Hits	602	Shared Neighborhood Hits	454
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

EDIL3_MOUSE
θ value	6.61148e-27 (rank : 73)	NC score	0.635539 (rank : 99)
Query Neighborhood Hits	1113	Target Neighborhood Hits	317	Shared Neighborhood Hits	290
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

FBLN4_MOUSE
θ value	1.47289e-26 (rank : 74)	NC score	0.711945 (rank : 69)
Query Neighborhood Hits	1113	Target Neighborhood Hits	270	Shared Neighborhood Hits	248
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

C1QR1_MOUSE
θ value	1.92365e-26 (rank : 75)	NC score	0.737960 (rank : 55)
Query Neighborhood Hits	1113	Target Neighborhood Hits	342	Shared Neighborhood Hits	298
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

EDIL3_HUMAN
θ value	7.30988e-26 (rank : 76)	NC score	0.626378 (rank : 107)
Query Neighborhood Hits	1113	Target Neighborhood Hits	292	Shared Neighborhood Hits	265
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

LRP1B_MOUSE
θ value	7.30988e-26 (rank : 77)	NC score	0.630180 (rank : 104)
Query Neighborhood Hits	1113	Target Neighborhood Hits	606	Shared Neighborhood Hits	457
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

FBLN5_HUMAN
θ value	9.54697e-26 (rank : 78)	NC score	0.715065 (rank : 63)
Query Neighborhood Hits	1113	Target Neighborhood Hits	329	Shared Neighborhood Hits	293
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

EMR1_HUMAN
θ value	1.62847e-25 (rank : 79)	NC score	0.629947 (rank : 105)
Query Neighborhood Hits	1113	Target Neighborhood Hits	382	Shared Neighborhood Hits	282
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

SREC2_HUMAN
θ value	1.05554e-24 (rank : 80)	NC score	0.730847 (rank : 56)
Query Neighborhood Hits	1113	Target Neighborhood Hits	645	Shared Neighborhood Hits	421
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SREC2_MOUSE
θ value	1.05554e-24 (rank : 81)	NC score	0.739056 (rank : 53)
Query Neighborhood Hits	1113	Target Neighborhood Hits	605	Shared Neighborhood Hits	421
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

LAMA5_HUMAN
θ value	1.37858e-24 (rank : 82)	NC score	0.578232 (rank : 128)
Query Neighborhood Hits	1113	Target Neighborhood Hits	976	Shared Neighborhood Hits	436
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

ZAN_MOUSE
θ value	3.07116e-24 (rank : 83)	NC score	0.602169 (rank : 115)
Query Neighborhood Hits	1113	Target Neighborhood Hits	808	Shared Neighborhood Hits	460
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

CSPG2_MOUSE
θ value	4.01107e-24 (rank : 84)	NC score	0.517432 (rank : 158)
Query Neighborhood Hits	1113	Target Neighborhood Hits	711	Shared Neighborhood Hits	326
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

FBLN3_HUMAN
θ value	5.23862e-24 (rank : 85)	NC score	0.709014 (rank : 72)
Query Neighborhood Hits	1113	Target Neighborhood Hits	293	Shared Neighborhood Hits	272
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

CSPG2_HUMAN
θ value	1.16704e-23 (rank : 86)	NC score	0.512798 (rank : 163)
Query Neighborhood Hits	1113	Target Neighborhood Hits	681	Shared Neighborhood Hits	317
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

FBLN3_MOUSE
θ value	1.16704e-23 (rank : 87)	NC score	0.702124 (rank : 73)
Query Neighborhood Hits	1113	Target Neighborhood Hits	279	Shared Neighborhood Hits	260
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

LAMA5_MOUSE
θ value	1.16704e-23 (rank : 88)	NC score	0.587598 (rank : 121)
Query Neighborhood Hits	1113	Target Neighborhood Hits	828	Shared Neighborhood Hits	390
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

CD97_HUMAN
θ value	2.59989e-23 (rank : 89)	NC score	0.597423 (rank : 117)
Query Neighborhood Hits	1113	Target Neighborhood Hits	353	Shared Neighborhood Hits	266
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

AGRIN_HUMAN
θ value	3.39556e-23 (rank : 90)	NC score	0.657185 (rank : 89)
Query Neighborhood Hits	1113	Target Neighborhood Hits	582	Shared Neighborhood Hits	408
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

EMR2_HUMAN
θ value	5.79196e-23 (rank : 91)	NC score	0.606095 (rank : 112)
Query Neighborhood Hits	1113	Target Neighborhood Hits	345	Shared Neighborhood Hits	264
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

STAB1_HUMAN
θ value	7.56453e-23 (rank : 92)	NC score	0.713010 (rank : 66)
Query Neighborhood Hits	1113	Target Neighborhood Hits	546	Shared Neighborhood Hits	421
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

C1QR1_HUMAN
θ value	1.29031e-22 (rank : 93)	NC score	0.738855 (rank : 54)
Query Neighborhood Hits	1113	Target Neighborhood Hits	493	Shared Neighborhood Hits	341
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

HABP2_MOUSE
θ value	1.29031e-22 (rank : 94)	NC score	0.363515 (rank : 420)
Query Neighborhood Hits	1113	Target Neighborhood Hits	445	Shared Neighborhood Hits	292
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

STAB2_HUMAN
θ value	2.87452e-22 (rank : 95)	NC score	0.718107 (rank : 61)
Query Neighborhood Hits	1113	Target Neighborhood Hits	534	Shared Neighborhood Hits	412
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

CSPG3_MOUSE
θ value	3.75424e-22 (rank : 96)	NC score	0.508387 (rank : 166)
Query Neighborhood Hits	1113	Target Neighborhood Hits	657	Shared Neighborhood Hits	317
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

LAMA2_HUMAN
θ value	3.75424e-22 (rank : 97)	NC score	0.516627 (rank : 160)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1092	Shared Neighborhood Hits	365
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

CELR1_MOUSE
θ value	6.40375e-22 (rank : 98)	NC score	0.369801 (rank : 405)
Query Neighborhood Hits	1113	Target Neighborhood Hits	617	Shared Neighborhood Hits	337
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

GAS6_MOUSE
θ value	8.36355e-22 (rank : 99)	NC score	0.719496 (rank : 59)
Query Neighborhood Hits	1113	Target Neighborhood Hits	343	Shared Neighborhood Hits	314
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

STAB2_MOUSE
θ value	8.36355e-22 (rank : 100)	NC score	0.713282 (rank : 65)
Query Neighborhood Hits	1113	Target Neighborhood Hits	528	Shared Neighborhood Hits	410
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

WIF1_MOUSE
θ value	1.42661e-21 (rank : 101)	NC score	0.763931 (rank : 47)
Query Neighborhood Hits	1113	Target Neighborhood Hits	393	Shared Neighborhood Hits	361
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

CELR3_HUMAN
θ value	2.43343e-21 (rank : 102)	NC score	0.384032 (rank : 375)
Query Neighborhood Hits	1113	Target Neighborhood Hits	680	Shared Neighborhood Hits	366
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

LAMA1_HUMAN
θ value	2.43343e-21 (rank : 103)	NC score	0.551390 (rank : 139)
Query Neighborhood Hits	1113	Target Neighborhood Hits	804	Shared Neighborhood Hits	355
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMB2_HUMAN
θ value	2.43343e-21 (rank : 104)	NC score	0.558537 (rank : 133)
Query Neighborhood Hits	1113	Target Neighborhood Hits	692	Shared Neighborhood Hits	327
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

NID2_HUMAN
θ value	2.43343e-21 (rank : 105)	NC score	0.664433 (rank : 85)
Query Neighborhood Hits	1113	Target Neighborhood Hits	456	Shared Neighborhood Hits	325
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

LAMC3_MOUSE
θ value	5.42112e-21 (rank : 106)	NC score	0.546616 (rank : 141)
Query Neighborhood Hits	1113	Target Neighborhood Hits	624	Shared Neighborhood Hits	322
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

CSPG3_HUMAN
θ value	7.0802e-21 (rank : 107)	NC score	0.502460 (rank : 173)
Query Neighborhood Hits	1113	Target Neighborhood Hits	676	Shared Neighborhood Hits	328
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

NID2_MOUSE
θ value	7.0802e-21 (rank : 108)	NC score	0.662804 (rank : 86)
Query Neighborhood Hits	1113	Target Neighborhood Hits	338	Shared Neighborhood Hits	283
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

WIF1_HUMAN
θ value	9.24701e-21 (rank : 109)	NC score	0.766180 (rank : 46)
Query Neighborhood Hits	1113	Target Neighborhood Hits	392	Shared Neighborhood Hits	363
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

HABP2_HUMAN
θ value	1.2077e-20 (rank : 110)	NC score	0.363994 (rank : 419)
Query Neighborhood Hits	1113	Target Neighborhood Hits	431	Shared Neighborhood Hits	277
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

LAMA2_MOUSE
θ value	1.5773e-20 (rank : 111)	NC score	0.492507 (rank : 180)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1198	Shared Neighborhood Hits	379
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

NID1_HUMAN
θ value	2.06002e-20 (rank : 112)	NC score	0.655253 (rank : 92)
Query Neighborhood Hits	1113	Target Neighborhood Hits	329	Shared Neighborhood Hits	284
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

ANR50_HUMAN
θ value	4.58923e-20 (rank : 113)	NC score	0.452627 (rank : 204)
Query Neighborhood Hits	1113	Target Neighborhood Hits	361	Shared Neighborhood Hits	288
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

ANKK1_HUMAN
θ value	5.99374e-20 (rank : 114)	NC score	0.287375 (rank : 500)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1075	Shared Neighborhood Hits	314
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

GAS6_HUMAN
θ value	5.99374e-20 (rank : 115)	NC score	0.716699 (rank : 62)
Query Neighborhood Hits	1113	Target Neighborhood Hits	348	Shared Neighborhood Hits	309
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

LAMA1_MOUSE
θ value	5.99374e-20 (rank : 116)	NC score	0.553790 (rank : 137)
Query Neighborhood Hits	1113	Target Neighborhood Hits	838	Shared Neighborhood Hits	364
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

NID1_MOUSE
θ value	5.99374e-20 (rank : 117)	NC score	0.656437 (rank : 90)
Query Neighborhood Hits	1113	Target Neighborhood Hits	335	Shared Neighborhood Hits	277
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

PROS_HUMAN
θ value	7.82807e-20 (rank : 118)	NC score	0.715023 (rank : 64)
Query Neighborhood Hits	1113	Target Neighborhood Hits	340	Shared Neighborhood Hits	318
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

CELR3_MOUSE
θ value	1.02238e-19 (rank : 119)	NC score	0.378787 (rank : 386)
Query Neighborhood Hits	1113	Target Neighborhood Hits	687	Shared Neighborhood Hits	373
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

STAB1_MOUSE
θ value	2.27762e-19 (rank : 120)	NC score	0.712165 (rank : 67)
Query Neighborhood Hits	1113	Target Neighborhood Hits	566	Shared Neighborhood Hits	433
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

ANK1_MOUSE
θ value	2.97466e-19 (rank : 121)	NC score	0.435524 (rank : 237)
Query Neighborhood Hits	1113	Target Neighborhood Hits	430	Shared Neighborhood Hits	292
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

CELR1_HUMAN
θ value	5.07402e-19 (rank : 122)	NC score	0.368497 (rank : 411)
Query Neighborhood Hits	1113	Target Neighborhood Hits	613	Shared Neighborhood Hits	335
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

DAPK1_HUMAN
θ value	5.07402e-19 (rank : 123)	NC score	0.195873 (rank : 626)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1130	Shared Neighborhood Hits	313
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

TRBM_HUMAN
θ value	5.07402e-19 (rank : 124)	NC score	0.712133 (rank : 68)
Query Neighborhood Hits	1113	Target Neighborhood Hits	339	Shared Neighborhood Hits	285
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

DAPK1_MOUSE
θ value	6.62687e-19 (rank : 125)	NC score	0.200113 (rank : 622)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1138	Shared Neighborhood Hits	315
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

LAMB1_MOUSE
θ value	6.62687e-19 (rank : 126)	NC score	0.516914 (rank : 159)
Query Neighborhood Hits	1113	Target Neighborhood Hits	919	Shared Neighborhood Hits	321
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

PROS_MOUSE
θ value	6.62687e-19 (rank : 127)	NC score	0.710686 (rank : 71)
Query Neighborhood Hits	1113	Target Neighborhood Hits	330	Shared Neighborhood Hits	308
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

TSP4_HUMAN
θ value	6.62687e-19 (rank : 128)	NC score	0.636648 (rank : 98)
Query Neighborhood Hits	1113	Target Neighborhood Hits	277	Shared Neighborhood Hits	250
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

LAMC3_HUMAN
θ value	8.65492e-19 (rank : 129)	NC score	0.539221 (rank : 145)
Query Neighborhood Hits	1113	Target Neighborhood Hits	588	Shared Neighborhood Hits	333
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMB2_MOUSE
θ value	1.13037e-18 (rank : 130)	NC score	0.552050 (rank : 138)
Query Neighborhood Hits	1113	Target Neighborhood Hits	722	Shared Neighborhood Hits	322
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

ANK1_HUMAN
θ value	1.47631e-18 (rank : 131)	NC score	0.433922 (rank : 241)
Query Neighborhood Hits	1113	Target Neighborhood Hits	416	Shared Neighborhood Hits	292
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

LAMB1_HUMAN
θ value	1.92812e-18 (rank : 132)	NC score	0.499936 (rank : 175)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1018	Shared Neighborhood Hits	336
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

TSP4_MOUSE
θ value	3.28887e-18 (rank : 133)	NC score	0.639443 (rank : 96)
Query Neighborhood Hits	1113	Target Neighborhood Hits	276	Shared Neighborhood Hits	257
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

ANK2_HUMAN
θ value	4.29542e-18 (rank : 134)	NC score	0.411404 (rank : 320)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1615	Shared Neighborhood Hits	445
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANK3_HUMAN
θ value	4.29542e-18 (rank : 135)	NC score	0.433289 (rank : 242)
Query Neighborhood Hits	1113	Target Neighborhood Hits	853	Shared Neighborhood Hits	348
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

UROM_HUMAN
θ value	4.29542e-18 (rank : 136)	NC score	0.668100 (rank : 83)
Query Neighborhood Hits	1113	Target Neighborhood Hits	284	Shared Neighborhood Hits	258
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

ANKK1_MOUSE
θ value	7.32683e-18 (rank : 137)	NC score	0.278912 (rank : 508)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1072	Shared Neighborhood Hits	313
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

ANR44_HUMAN
θ value	7.32683e-18 (rank : 138)	NC score	0.441760 (rank : 218)
Query Neighborhood Hits	1113	Target Neighborhood Hits	318	Shared Neighborhood Hits	286
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

CELR2_HUMAN
θ value	9.56915e-18 (rank : 139)	NC score	0.385471 (rank : 371)
Query Neighborhood Hits	1113	Target Neighborhood Hits	657	Shared Neighborhood Hits	382
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

UROM_MOUSE
θ value	1.63225e-17 (rank : 140)	NC score	0.656194 (rank : 91)
Query Neighborhood Hits	1113	Target Neighborhood Hits	276	Shared Neighborhood Hits	253
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

ANR28_MOUSE
θ value	3.63628e-17 (rank : 141)	NC score	0.439831 (rank : 222)
Query Neighborhood Hits	1113	Target Neighborhood Hits	314	Shared Neighborhood Hits	285
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

CELR2_MOUSE
θ value	4.74913e-17 (rank : 142)	NC score	0.350766 (rank : 436)
Query Neighborhood Hits	1113	Target Neighborhood Hits	584	Shared Neighborhood Hits	325
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

LAMC1_MOUSE
θ value	4.74913e-17 (rank : 143)	NC score	0.506590 (rank : 169)
Query Neighborhood Hits	1113	Target Neighborhood Hits	856	Shared Neighborhood Hits	322
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

ANR28_HUMAN
θ value	6.20254e-17 (rank : 144)	NC score	0.437675 (rank : 229)
Query Neighborhood Hits	1113	Target Neighborhood Hits	314	Shared Neighborhood Hits	284
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

EGF_MOUSE
θ value	6.20254e-17 (rank : 145)	NC score	0.665676 (rank : 84)
Query Neighborhood Hits	1113	Target Neighborhood Hits	358	Shared Neighborhood Hits	326
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

ANR52_MOUSE
θ value	1.80466e-16 (rank : 146)	NC score	0.436911 (rank : 230)
Query Neighborhood Hits	1113	Target Neighborhood Hits	318	Shared Neighborhood Hits	283
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

COMP_MOUSE
θ value	2.35696e-16 (rank : 147)	NC score	0.617748 (rank : 108)
Query Neighborhood Hits	1113	Target Neighborhood Hits	290	Shared Neighborhood Hits	252
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

TNKS2_HUMAN
θ value	3.07829e-16 (rank : 148)	NC score	0.432901 (rank : 244)
Query Neighborhood Hits	1113	Target Neighborhood Hits	361	Shared Neighborhood Hits	285
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

ANR52_HUMAN
θ value	5.25075e-16 (rank : 149)	NC score	0.436279 (rank : 233)
Query Neighborhood Hits	1113	Target Neighborhood Hits	322	Shared Neighborhood Hits	284
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

PSD10_HUMAN
θ value	5.25075e-16 (rank : 150)	NC score	0.458649 (rank : 198)
Query Neighborhood Hits	1113	Target Neighborhood Hits	301	Shared Neighborhood Hits	279
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

TRBM_MOUSE
θ value	5.25075e-16 (rank : 151)	NC score	0.698067 (rank : 75)
Query Neighborhood Hits	1113	Target Neighborhood Hits	361	Shared Neighborhood Hits	290
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

LAMC1_HUMAN
θ value	6.85773e-16 (rank : 152)	NC score	0.493061 (rank : 179)
Query Neighborhood Hits	1113	Target Neighborhood Hits	922	Shared Neighborhood Hits	330
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

PGBM_MOUSE
θ value	6.85773e-16 (rank : 153)	NC score	0.428999 (rank : 250)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1073	Shared Neighborhood Hits	411
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

RAI14_HUMAN
θ value	8.95645e-16 (rank : 154)	NC score	0.333855 (rank : 462)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1367	Shared Neighborhood Hits	329
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

USH2A_MOUSE
θ value	1.52774e-15 (rank : 155)	NC score	0.472225 (rank : 188)
Query Neighborhood Hits	1113	Target Neighborhood Hits	626	Shared Neighborhood Hits	323
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

PSD10_MOUSE
θ value	2.60593e-15 (rank : 156)	NC score	0.457236 (rank : 200)
Query Neighborhood Hits	1113	Target Neighborhood Hits	293	Shared Neighborhood Hits	279
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

VLDLR_HUMAN
θ value	2.60593e-15 (rank : 157)	NC score	0.542620 (rank : 143)
Query Neighborhood Hits	1113	Target Neighborhood Hits	383	Shared Neighborhood Hits	307
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

ASB2_MOUSE
θ value	3.40345e-15 (rank : 158)	NC score	0.438366 (rank : 224)
Query Neighborhood Hits	1113	Target Neighborhood Hits	321	Shared Neighborhood Hits	278
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

TSP3_MOUSE
θ value	4.44505e-15 (rank : 159)	NC score	0.580586 (rank : 126)
Query Neighborhood Hits	1113	Target Neighborhood Hits	247	Shared Neighborhood Hits	223
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

EHMT2_HUMAN
θ value	7.58209e-15 (rank : 160)	NC score	0.414813 (rank : 310)
Query Neighborhood Hits	1113	Target Neighborhood Hits	498	Shared Neighborhood Hits	311
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

FAT2_HUMAN
θ value	7.58209e-15 (rank : 161)	NC score	0.276315 (rank : 513)
Query Neighborhood Hits	1113	Target Neighborhood Hits	507	Shared Neighborhood Hits	276
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

VLDLR_MOUSE
θ value	7.58209e-15 (rank : 162)	NC score	0.540680 (rank : 144)
Query Neighborhood Hits	1113	Target Neighborhood Hits	360	Shared Neighborhood Hits	295
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

ANKR6_HUMAN
θ value	9.90251e-15 (rank : 163)	NC score	0.451803 (rank : 205)
Query Neighborhood Hits	1113	Target Neighborhood Hits	439	Shared Neighborhood Hits	298
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ASB2_HUMAN
θ value	9.90251e-15 (rank : 164)	NC score	0.440889 (rank : 220)
Query Neighborhood Hits	1113	Target Neighborhood Hits	309	Shared Neighborhood Hits	276
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ASB3_MOUSE
θ value	9.90251e-15 (rank : 165)	NC score	0.439402 (rank : 223)
Query Neighborhood Hits	1113	Target Neighborhood Hits	316	Shared Neighborhood Hits	281
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ANFY1_HUMAN
θ value	1.29331e-14 (rank : 166)	NC score	0.402684 (rank : 337)
Query Neighborhood Hits	1113	Target Neighborhood Hits	480	Shared Neighborhood Hits	283
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANFY1_MOUSE
θ value	1.29331e-14 (rank : 167)	NC score	0.403159 (rank : 336)
Query Neighborhood Hits	1113	Target Neighborhood Hits	480	Shared Neighborhood Hits	287
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

LRP2_HUMAN
θ value	1.29331e-14 (rank : 168)	NC score	0.558354 (rank : 134)
Query Neighborhood Hits	1113	Target Neighborhood Hits	573	Shared Neighborhood Hits	436
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

TENR_HUMAN
θ value	1.29331e-14 (rank : 169)	NC score	0.427380 (rank : 254)
Query Neighborhood Hits	1113	Target Neighborhood Hits	526	Shared Neighborhood Hits	321
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TSP3_HUMAN
θ value	1.29331e-14 (rank : 170)	NC score	0.572381 (rank : 129)
Query Neighborhood Hits	1113	Target Neighborhood Hits	250	Shared Neighborhood Hits	219
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

MYPT1_MOUSE
θ value	1.68911e-14 (rank : 171)	NC score	0.423495 (rank : 282)
Query Neighborhood Hits	1113	Target Neighborhood Hits	539	Shared Neighborhood Hits	292
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

ASB3_HUMAN
θ value	2.20605e-14 (rank : 172)	NC score	0.444137 (rank : 216)
Query Neighborhood Hits	1113	Target Neighborhood Hits	316	Shared Neighborhood Hits	281
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

INVS_HUMAN
θ value	2.88119e-14 (rank : 173)	NC score	0.437792 (rank : 226)
Query Neighborhood Hits	1113	Target Neighborhood Hits	455	Shared Neighborhood Hits	302
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

TENR_MOUSE
θ value	2.88119e-14 (rank : 174)	NC score	0.434405 (rank : 239)
Query Neighborhood Hits	1113	Target Neighborhood Hits	531	Shared Neighborhood Hits	326
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

INVS_MOUSE
θ value	3.76295e-14 (rank : 175)	NC score	0.435859 (rank : 236)
Query Neighborhood Hits	1113	Target Neighborhood Hits	609	Shared Neighborhood Hits	349
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

RN5A_MOUSE
θ value	3.76295e-14 (rank : 176)	NC score	0.392431 (rank : 360)
Query Neighborhood Hits	1113	Target Neighborhood Hits	899	Shared Neighborhood Hits	300
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

LDLR_HUMAN
θ value	4.91457e-14 (rank : 177)	NC score	0.549911 (rank : 140)
Query Neighborhood Hits	1113	Target Neighborhood Hits	375	Shared Neighborhood Hits	317
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

MYPT1_HUMAN
θ value	4.91457e-14 (rank : 178)	NC score	0.413832 (rank : 315)
Query Neighborhood Hits	1113	Target Neighborhood Hits	723	Shared Neighborhood Hits	296
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

PGBM_HUMAN
θ value	4.91457e-14 (rank : 179)	NC score	0.424560 (rank : 275)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1113	Shared Neighborhood Hits	425
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

TNKS1_HUMAN
θ value	4.91457e-14 (rank : 180)	NC score	0.432762 (rank : 245)
Query Neighborhood Hits	1113	Target Neighborhood Hits	477	Shared Neighborhood Hits	317
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

EGF_HUMAN
θ value	6.41864e-14 (rank : 181)	NC score	0.632939 (rank : 102)
Query Neighborhood Hits	1113	Target Neighborhood Hits	343	Shared Neighborhood Hits	307
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

RIPK4_HUMAN
θ value	6.41864e-14 (rank : 182)	NC score	0.275622 (rank : 515)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1094	Shared Neighborhood Hits	320
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

EHMT2_MOUSE
θ value	8.38298e-14 (rank : 183)	NC score	0.408895 (rank : 325)
Query Neighborhood Hits	1113	Target Neighborhood Hits	750	Shared Neighborhood Hits	376
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ASB14_MOUSE
θ value	1.42992e-13 (rank : 184)	NC score	0.429687 (rank : 249)
Query Neighborhood Hits	1113	Target Neighborhood Hits	293	Shared Neighborhood Hits	271
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

MFGM_MOUSE
θ value	1.42992e-13 (rank : 185)	NC score	0.458687 (rank : 197)
Query Neighborhood Hits	1113	Target Neighborhood Hits	233	Shared Neighborhood Hits	207
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

PCSK5_MOUSE
θ value	1.42992e-13 (rank : 186)	NC score	0.442145 (rank : 217)
Query Neighborhood Hits	1113	Target Neighborhood Hits	613	Shared Neighborhood Hits	352
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

USH2A_HUMAN
θ value	2.43908e-13 (rank : 187)	NC score	0.448848 (rank : 208)
Query Neighborhood Hits	1113	Target Neighborhood Hits	600	Shared Neighborhood Hits	290
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

ELTD1_MOUSE
θ value	3.18553e-13 (rank : 188)	NC score	0.505634 (rank : 171)
Query Neighborhood Hits	1113	Target Neighborhood Hits	288	Shared Neighborhood Hits	215
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

HGFA_HUMAN
θ value	3.18553e-13 (rank : 189)	NC score	0.283392 (rank : 503)
Query Neighborhood Hits	1113	Target Neighborhood Hits	436	Shared Neighborhood Hits	252
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

ANR23_HUMAN
θ value	4.16044e-13 (rank : 190)	NC score	0.445224 (rank : 212)
Query Neighborhood Hits	1113	Target Neighborhood Hits	291	Shared Neighborhood Hits	277
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

COMP_HUMAN
θ value	4.16044e-13 (rank : 191)	NC score	0.595565 (rank : 119)
Query Neighborhood Hits	1113	Target Neighborhood Hits	258	Shared Neighborhood Hits	234
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

PP16A_MOUSE
θ value	5.43371e-13 (rank : 192)	NC score	0.426600 (rank : 260)
Query Neighborhood Hits	1113	Target Neighborhood Hits	318	Shared Neighborhood Hits	275
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

PA2G6_MOUSE
θ value	7.09661e-13 (rank : 193)	NC score	0.435872 (rank : 235)
Query Neighborhood Hits	1113	Target Neighborhood Hits	293	Shared Neighborhood Hits	275
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ANKS1_HUMAN
θ value	9.26847e-13 (rank : 194)	NC score	0.416967 (rank : 300)
Query Neighborhood Hits	1113	Target Neighborhood Hits	438	Shared Neighborhood Hits	290
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ASB16_MOUSE
θ value	9.26847e-13 (rank : 195)	NC score	0.440778 (rank : 221)
Query Neighborhood Hits	1113	Target Neighborhood Hits	306	Shared Neighborhood Hits	274
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

HGFA_MOUSE
θ value	9.26847e-13 (rank : 196)	NC score	0.279267 (rank : 507)
Query Neighborhood Hits	1113	Target Neighborhood Hits	419	Shared Neighborhood Hits	254
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

AN36B_HUMAN
θ value	1.2105e-12 (rank : 197)	NC score	0.426729 (rank : 258)
Query Neighborhood Hits	1113	Target Neighborhood Hits	294	Shared Neighborhood Hits	268
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

ANR18_HUMAN
θ value	1.2105e-12 (rank : 198)	NC score	0.325332 (rank : 470)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1106	Shared Neighborhood Hits	295
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ASB8_HUMAN
θ value	1.2105e-12 (rank : 199)	NC score	0.444963 (rank : 213)
Query Neighborhood Hits	1113	Target Neighborhood Hits	294	Shared Neighborhood Hits	276
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

RN5A_HUMAN
θ value	1.2105e-12 (rank : 200)	NC score	0.422119 (rank : 286)
Query Neighborhood Hits	1113	Target Neighborhood Hits	608	Shared Neighborhood Hits	282
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

UACA_MOUSE
θ value	1.2105e-12 (rank : 201)	NC score	0.258029 (rank : 539)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1620	Shared Neighborhood Hits	329
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

ASB8_MOUSE
θ value	2.0648e-12 (rank : 202)	NC score	0.444299 (rank : 215)
Query Neighborhood Hits	1113	Target Neighborhood Hits	293	Shared Neighborhood Hits	274
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

CD97_MOUSE
θ value	2.0648e-12 (rank : 203)	NC score	0.518008 (rank : 157)
Query Neighborhood Hits	1113	Target Neighborhood Hits	295	Shared Neighborhood Hits	221
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

MYPT2_HUMAN
θ value	2.0648e-12 (rank : 204)	NC score	0.415834 (rank : 307)
Query Neighborhood Hits	1113	Target Neighborhood Hits	707	Shared Neighborhood Hits	292
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

PA2G6_HUMAN
θ value	2.0648e-12 (rank : 205)	NC score	0.437767 (rank : 227)
Query Neighborhood Hits	1113	Target Neighborhood Hits	284	Shared Neighborhood Hits	272
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

UACA_HUMAN
θ value	2.0648e-12 (rank : 206)	NC score	0.268634 (rank : 521)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1622	Shared Neighborhood Hits	327
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

ANR29_HUMAN
θ value	2.69671e-12 (rank : 207)	NC score	0.450024 (rank : 207)
Query Neighborhood Hits	1113	Target Neighborhood Hits	294	Shared Neighborhood Hits	277
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

FA7_HUMAN
θ value	3.52202e-12 (rank : 208)	NC score	0.287013 (rank : 501)
Query Neighborhood Hits	1113	Target Neighborhood Hits	404	Shared Neighborhood Hits	253
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

MEGF8_MOUSE
θ value	3.52202e-12 (rank : 209)	NC score	0.646542 (rank : 94)
Query Neighborhood Hits	1113	Target Neighborhood Hits	520	Shared Neighborhood Hits	350
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

SHAN1_HUMAN
θ value	3.52202e-12 (rank : 210)	NC score	0.385346 (rank : 372)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1041	Shared Neighborhood Hits	352
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

TSP1_HUMAN
θ value	3.52202e-12 (rank : 211)	NC score	0.458020 (rank : 199)
Query Neighborhood Hits	1113	Target Neighborhood Hits	389	Shared Neighborhood Hits	267
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

BCL3_HUMAN
θ value	4.59992e-12 (rank : 212)	NC score	0.447306 (rank : 210)
Query Neighborhood Hits	1113	Target Neighborhood Hits	324	Shared Neighborhood Hits	285
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

MIB1_HUMAN
θ value	4.59992e-12 (rank : 213)	NC score	0.415459 (rank : 308)
Query Neighborhood Hits	1113	Target Neighborhood Hits	470	Shared Neighborhood Hits	294
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	4.59992e-12 (rank : 214)	NC score	0.414612 (rank : 312)
Query Neighborhood Hits	1113	Target Neighborhood Hits	471	Shared Neighborhood Hits	292
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

EHMT1_HUMAN
θ value	6.00763e-12 (rank : 215)	NC score	0.411182 (rank : 321)
Query Neighborhood Hits	1113	Target Neighborhood Hits	417	Shared Neighborhood Hits	299
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

TENN_MOUSE
θ value	6.00763e-12 (rank : 216)	NC score	0.369074 (rank : 407)
Query Neighborhood Hits	1113	Target Neighborhood Hits	484	Shared Neighborhood Hits	286
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

ANR35_HUMAN
θ value	7.84624e-12 (rank : 217)	NC score	0.409982 (rank : 323)
Query Neighborhood Hits	1113	Target Neighborhood Hits	784	Shared Neighborhood Hits	302
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

BCL3_MOUSE
θ value	7.84624e-12 (rank : 218)	NC score	0.444618 (rank : 214)
Query Neighborhood Hits	1113	Target Neighborhood Hits	388	Shared Neighborhood Hits	307
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

LAMC2_HUMAN
θ value	7.84624e-12 (rank : 219)	NC score	0.507781 (rank : 168)
Query Neighborhood Hits	1113	Target Neighborhood Hits	715	Shared Neighborhood Hits	302
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

RAI14_MOUSE
θ value	7.84624e-12 (rank : 220)	NC score	0.309533 (rank : 481)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1505	Shared Neighborhood Hits	337
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

TIE1_HUMAN
θ value	7.84624e-12 (rank : 221)	NC score	0.216474 (rank : 604)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1241	Shared Neighborhood Hits	340
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

LAMC2_MOUSE
θ value	1.33837e-11 (rank : 222)	NC score	0.527278 (rank : 154)
Query Neighborhood Hits	1113	Target Neighborhood Hits	614	Shared Neighborhood Hits	304
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

TSP1_MOUSE
θ value	1.33837e-11 (rank : 223)	NC score	0.461379 (rank : 194)
Query Neighborhood Hits	1113	Target Neighborhood Hits	396	Shared Neighborhood Hits	271
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

ANR26_MOUSE
θ value	1.74796e-11 (rank : 224)	NC score	0.248673 (rank : 556)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1554	Shared Neighborhood Hits	334
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ASB15_HUMAN
θ value	1.74796e-11 (rank : 225)	NC score	0.425193 (rank : 271)
Query Neighborhood Hits	1113	Target Neighborhood Hits	305	Shared Neighborhood Hits	273
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ANR15_HUMAN
θ value	2.28291e-11 (rank : 226)	NC score	0.405270 (rank : 331)
Query Neighborhood Hits	1113	Target Neighborhood Hits	478	Shared Neighborhood Hits	276
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

CSKI1_MOUSE
θ value	2.28291e-11 (rank : 227)	NC score	0.414543 (rank : 314)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1031	Shared Neighborhood Hits	446
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

SUSD1_HUMAN
θ value	2.28291e-11 (rank : 228)	NC score	0.660551 (rank : 87)
Query Neighborhood Hits	1113	Target Neighborhood Hits	285	Shared Neighborhood Hits	234
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

ITB1_HUMAN
θ value	2.98157e-11 (rank : 229)	NC score	0.431104 (rank : 246)
Query Neighborhood Hits	1113	Target Neighborhood Hits	298	Shared Neighborhood Hits	251
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

CORIN_HUMAN
θ value	3.89403e-11 (rank : 230)	NC score	0.215128 (rank : 606)
Query Neighborhood Hits	1113	Target Neighborhood Hits	453	Shared Neighborhood Hits	240
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

MEGF8_HUMAN
θ value	3.89403e-11 (rank : 231)	NC score	0.649914 (rank : 93)
Query Neighborhood Hits	1113	Target Neighborhood Hits	528	Shared Neighborhood Hits	357
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

PP16B_HUMAN
θ value	3.89403e-11 (rank : 232)	NC score	0.416413 (rank : 303)
Query Neighborhood Hits	1113	Target Neighborhood Hits	307	Shared Neighborhood Hits	275
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

ASB16_HUMAN
θ value	5.08577e-11 (rank : 233)	NC score	0.424349 (rank : 276)
Query Neighborhood Hits	1113	Target Neighborhood Hits	286	Shared Neighborhood Hits	268
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ITB6_HUMAN
θ value	5.08577e-11 (rank : 234)	NC score	0.475739 (rank : 185)
Query Neighborhood Hits	1113	Target Neighborhood Hits	318	Shared Neighborhood Hits	272
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

LAMB3_MOUSE
θ value	5.08577e-11 (rank : 235)	NC score	0.496515 (rank : 178)
Query Neighborhood Hits	1113	Target Neighborhood Hits	444	Shared Neighborhood Hits	254
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

MATN3_MOUSE
θ value	5.08577e-11 (rank : 236)	NC score	0.536497 (rank : 147)
Query Neighborhood Hits	1113	Target Neighborhood Hits	261	Shared Neighborhood Hits	216
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

TIE1_MOUSE
θ value	5.08577e-11 (rank : 237)	NC score	0.212769 (rank : 610)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1266	Shared Neighborhood Hits	336
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

CSKI1_HUMAN
θ value	6.64225e-11 (rank : 238)	NC score	0.409594 (rank : 324)
Query Neighborhood Hits	1113	Target Neighborhood Hits	997	Shared Neighborhood Hits	406
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

LAMA3_MOUSE
θ value	6.64225e-11 (rank : 239)	NC score	0.479479 (rank : 184)
Query Neighborhood Hits	1113	Target Neighborhood Hits	859	Shared Neighborhood Hits	357
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

MATN3_HUMAN
θ value	6.64225e-11 (rank : 240)	NC score	0.534057 (rank : 148)
Query Neighborhood Hits	1113	Target Neighborhood Hits	268	Shared Neighborhood Hits	213
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

PP16B_MOUSE
θ value	6.64225e-11 (rank : 241)	NC score	0.414756 (rank : 311)
Query Neighborhood Hits	1113	Target Neighborhood Hits	302	Shared Neighborhood Hits	273
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

TRPA1_MOUSE
θ value	6.64225e-11 (rank : 242)	NC score	0.427199 (rank : 256)
Query Neighborhood Hits	1113	Target Neighborhood Hits	343	Shared Neighborhood Hits	282
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

TSP2_MOUSE
θ value	6.64225e-11 (rank : 243)	NC score	0.416098 (rank : 305)
Query Neighborhood Hits	1113	Target Neighborhood Hits	352	Shared Neighborhood Hits	252
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

LAMB3_HUMAN
θ value	8.67504e-11 (rank : 244)	NC score	0.464222 (rank : 193)
Query Neighborhood Hits	1113	Target Neighborhood Hits	461	Shared Neighborhood Hits	226
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

ANR42_MOUSE
θ value	1.133e-10 (rank : 245)	NC score	0.424586 (rank : 274)
Query Neighborhood Hits	1113	Target Neighborhood Hits	334	Shared Neighborhood Hits	272
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ITB1_MOUSE
θ value	1.133e-10 (rank : 246)	NC score	0.434237 (rank : 240)
Query Neighborhood Hits	1113	Target Neighborhood Hits	283	Shared Neighborhood Hits	239
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

LDLR_MOUSE
θ value	1.133e-10 (rank : 247)	NC score	0.522607 (rank : 156)
Query Neighborhood Hits	1113	Target Neighborhood Hits	382	Shared Neighborhood Hits	310
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

TIE2_MOUSE
θ value	1.133e-10 (rank : 248)	NC score	0.186830 (rank : 643)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1204	Shared Neighborhood Hits	313
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

ANR23_MOUSE
θ value	1.47974e-10 (rank : 249)	NC score	0.437722 (rank : 228)
Query Neighborhood Hits	1113	Target Neighborhood Hits	296	Shared Neighborhood Hits	274
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

FRAS1_MOUSE
θ value	1.47974e-10 (rank : 250)	NC score	0.390023 (rank : 363)
Query Neighborhood Hits	1113	Target Neighborhood Hits	747	Shared Neighborhood Hits	330
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

GABP2_HUMAN
θ value	1.47974e-10 (rank : 251)	NC score	0.435913 (rank : 234)
Query Neighborhood Hits	1113	Target Neighborhood Hits	454	Shared Neighborhood Hits	282
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

ITB4_HUMAN
θ value	1.47974e-10 (rank : 252)	NC score	0.427369 (rank : 255)
Query Neighborhood Hits	1113	Target Neighborhood Hits	458	Shared Neighborhood Hits	271
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

KR107_HUMAN
θ value	1.47974e-10 (rank : 253)	NC score	0.584571 (rank : 122)
Query Neighborhood Hits	1113	Target Neighborhood Hits	330	Shared Neighborhood Hits	266
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

ANR38_MOUSE
θ value	2.52405e-10 (rank : 254)	NC score	0.375372 (rank : 397)
Query Neighborhood Hits	1113	Target Neighborhood Hits	512	Shared Neighborhood Hits	247
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

PP16A_HUMAN
θ value	2.52405e-10 (rank : 255)	NC score	0.418786 (rank : 295)
Query Neighborhood Hits	1113	Target Neighborhood Hits	340	Shared Neighborhood Hits	279
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

ITB2_HUMAN
θ value	3.29651e-10 (rank : 256)	NC score	0.430992 (rank : 247)
Query Neighborhood Hits	1113	Target Neighborhood Hits	282	Shared Neighborhood Hits	245
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

MIB2_HUMAN
θ value	3.29651e-10 (rank : 257)	NC score	0.414569 (rank : 313)
Query Neighborhood Hits	1113	Target Neighborhood Hits	438	Shared Neighborhood Hits	287
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

PROZ_HUMAN
θ value	3.29651e-10 (rank : 258)	NC score	0.529151 (rank : 152)
Query Neighborhood Hits	1113	Target Neighborhood Hits	422	Shared Neighborhood Hits	282
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

ANR21_HUMAN
θ value	4.30538e-10 (rank : 259)	NC score	0.377838 (rank : 390)
Query Neighborhood Hits	1113	Target Neighborhood Hits	864	Shared Neighborhood Hits	299
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

GABP2_MOUSE
θ value	4.30538e-10 (rank : 260)	NC score	0.436333 (rank : 232)
Query Neighborhood Hits	1113	Target Neighborhood Hits	429	Shared Neighborhood Hits	282
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

NFKB1_HUMAN
θ value	4.30538e-10 (rank : 261)	NC score	0.376494 (rank : 393)
Query Neighborhood Hits	1113	Target Neighborhood Hits	306	Shared Neighborhood Hits	273
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

SORL_MOUSE
θ value	4.30538e-10 (rank : 262)	NC score	0.379833 (rank : 384)
Query Neighborhood Hits	1113	Target Neighborhood Hits	439	Shared Neighborhood Hits	260
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

TIE2_HUMAN
θ value	4.30538e-10 (rank : 263)	NC score	0.187826 (rank : 642)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1192	Shared Neighborhood Hits	306
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TRPA1_HUMAN
θ value	4.30538e-10 (rank : 264)	NC score	0.423217 (rank : 284)
Query Neighborhood Hits	1113	Target Neighborhood Hits	339	Shared Neighborhood Hits	281
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

CTTB2_HUMAN
θ value	5.62301e-10 (rank : 265)	NC score	0.365067 (rank : 417)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1061	Shared Neighborhood Hits	318
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

POT15_HUMAN
θ value	5.62301e-10 (rank : 266)	NC score	0.376348 (rank : 394)
Query Neighborhood Hits	1113	Target Neighborhood Hits	893	Shared Neighborhood Hits	301
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

ADA11_HUMAN
θ value	7.34386e-10 (rank : 267)	NC score	0.217778 (rank : 600)
Query Neighborhood Hits	1113	Target Neighborhood Hits	259	Shared Neighborhood Hits	198
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

CREL1_HUMAN
θ value	7.34386e-10 (rank : 268)	NC score	0.685190 (rank : 78)
Query Neighborhood Hits	1113	Target Neighborhood Hits	441	Shared Neighborhood Hits	285
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

FA9_HUMAN
θ value	7.34386e-10 (rank : 269)	NC score	0.301929 (rank : 485)
Query Neighborhood Hits	1113	Target Neighborhood Hits	421	Shared Neighborhood Hits	270
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

SORL_HUMAN
θ value	7.34386e-10 (rank : 270)	NC score	0.368558 (rank : 410)
Query Neighborhood Hits	1113	Target Neighborhood Hits	440	Shared Neighborhood Hits	251
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SSPO_MOUSE
θ value	7.34386e-10 (rank : 271)	NC score	0.416913 (rank : 301)
Query Neighborhood Hits	1113	Target Neighborhood Hits	800	Shared Neighborhood Hits	419
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

FA12_HUMAN
θ value	9.59137e-10 (rank : 272)	NC score	0.259938 (rank : 534)
Query Neighborhood Hits	1113	Target Neighborhood Hits	425	Shared Neighborhood Hits	248
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

KR104_HUMAN
θ value	9.59137e-10 (rank : 273)	NC score	0.579151 (rank : 127)
Query Neighborhood Hits	1113	Target Neighborhood Hits	313	Shared Neighborhood Hits	252
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

LRP8_HUMAN
θ value	1.25267e-09 (rank : 274)	NC score	0.513227 (rank : 162)
Query Neighborhood Hits	1113	Target Neighborhood Hits	346	Shared Neighborhood Hits	273
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

PROC_MOUSE
θ value	1.25267e-09 (rank : 275)	NC score	0.299814 (rank : 488)
Query Neighborhood Hits	1113	Target Neighborhood Hits	426	Shared Neighborhood Hits	275
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

A20A3_HUMAN
θ value	1.63604e-09 (rank : 276)	NC score	0.346527 (rank : 441)
Query Neighborhood Hits	1113	Target Neighborhood Hits	692	Shared Neighborhood Hits	278
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A4_HUMAN
θ value	1.63604e-09 (rank : 277)	NC score	0.344222 (rank : 446)
Query Neighborhood Hits	1113	Target Neighborhood Hits	710	Shared Neighborhood Hits	279
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

ITB6_MOUSE
θ value	1.63604e-09 (rank : 278)	NC score	0.492422 (rank : 181)
Query Neighborhood Hits	1113	Target Neighborhood Hits	341	Shared Neighborhood Hits	286
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

TSP2_HUMAN
θ value	1.63604e-09 (rank : 279)	NC score	0.422246 (rank : 285)
Query Neighborhood Hits	1113	Target Neighborhood Hits	359	Shared Neighborhood Hits	256
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

ADA11_MOUSE
θ value	2.13673e-09 (rank : 280)	NC score	0.216458 (rank : 605)
Query Neighborhood Hits	1113	Target Neighborhood Hits	263	Shared Neighborhood Hits	201
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ANKS3_HUMAN
θ value	2.13673e-09 (rank : 281)	NC score	0.421980 (rank : 287)
Query Neighborhood Hits	1113	Target Neighborhood Hits	355	Shared Neighborhood Hits	269
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

CREL1_MOUSE
θ value	2.13673e-09 (rank : 282)	NC score	0.672924 (rank : 80)
Query Neighborhood Hits	1113	Target Neighborhood Hits	524	Shared Neighborhood Hits	296
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

FA7_MOUSE
θ value	2.13673e-09 (rank : 283)	NC score	0.250291 (rank : 554)
Query Neighborhood Hits	1113	Target Neighborhood Hits	374	Shared Neighborhood Hits	228
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

FRAS1_HUMAN
θ value	2.13673e-09 (rank : 284)	NC score	0.407340 (rank : 327)
Query Neighborhood Hits	1113	Target Neighborhood Hits	759	Shared Neighborhood Hits	345
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

KR106_HUMAN
θ value	2.13673e-09 (rank : 285)	NC score	0.582050 (rank : 125)
Query Neighborhood Hits	1113	Target Neighborhood Hits	347	Shared Neighborhood Hits	275
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

LRP4_HUMAN
θ value	2.13673e-09 (rank : 286)	NC score	0.482597 (rank : 183)
Query Neighborhood Hits	1113	Target Neighborhood Hits	355	Shared Neighborhood Hits	287
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

ZDH13_HUMAN
θ value	2.13673e-09 (rank : 287)	NC score	0.384138 (rank : 374)
Query Neighborhood Hits	1113	Target Neighborhood Hits	322	Shared Neighborhood Hits	273
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

ANR47_MOUSE
θ value	2.79066e-09 (rank : 288)	NC score	0.400942 (rank : 339)
Query Neighborhood Hits	1113	Target Neighborhood Hits	350	Shared Neighborhood Hits	257
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ASZ1_HUMAN
θ value	2.79066e-09 (rank : 289)	NC score	0.423905 (rank : 279)
Query Neighborhood Hits	1113	Target Neighborhood Hits	341	Shared Neighborhood Hits	268
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

NTNG1_HUMAN
θ value	2.79066e-09 (rank : 290)	NC score	0.472047 (rank : 189)
Query Neighborhood Hits	1113	Target Neighborhood Hits	247	Shared Neighborhood Hits	215
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

TNI3K_MOUSE
θ value	2.79066e-09 (rank : 291)	NC score	0.210737 (rank : 612)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1079	Shared Neighborhood Hits	315
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

EGFL8_MOUSE
θ value	3.64472e-09 (rank : 292)	NC score	0.672712 (rank : 81)
Query Neighborhood Hits	1113	Target Neighborhood Hits	266	Shared Neighborhood Hits	259
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

FA10_MOUSE
θ value	3.64472e-09 (rank : 293)	NC score	0.316729 (rank : 473)
Query Neighborhood Hits	1113	Target Neighborhood Hits	435	Shared Neighborhood Hits	282
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

ANKS6_MOUSE
θ value	4.76016e-09 (rank : 294)	NC score	0.415921 (rank : 306)
Query Neighborhood Hits	1113	Target Neighborhood Hits	435	Shared Neighborhood Hits	302
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ANR47_HUMAN
θ value	4.76016e-09 (rank : 295)	NC score	0.392785 (rank : 358)
Query Neighborhood Hits	1113	Target Neighborhood Hits	369	Shared Neighborhood Hits	255
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

EGFL8_HUMAN
θ value	4.76016e-09 (rank : 296)	NC score	0.668473 (rank : 82)
Query Neighborhood Hits	1113	Target Neighborhood Hits	270	Shared Neighborhood Hits	254
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

HECD1_HUMAN
θ value	4.76016e-09 (rank : 297)	NC score	0.330483 (rank : 464)
Query Neighborhood Hits	1113	Target Neighborhood Hits	371	Shared Neighborhood Hits	269
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

LYAM3_HUMAN
θ value	4.76016e-09 (rank : 298)	NC score	0.345426 (rank : 443)
Query Neighborhood Hits	1113	Target Neighborhood Hits	378	Shared Neighborhood Hits	244
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

A20A1_HUMAN
θ value	6.21693e-09 (rank : 299)	NC score	0.345206 (rank : 444)
Query Neighborhood Hits	1113	Target Neighborhood Hits	698	Shared Neighborhood Hits	275
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

A20A2_HUMAN
θ value	6.21693e-09 (rank : 300)	NC score	0.344543 (rank : 445)
Query Neighborhood Hits	1113	Target Neighborhood Hits	716	Shared Neighborhood Hits	278
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

ANKS3_MOUSE
θ value	6.21693e-09 (rank : 301)	NC score	0.421084 (rank : 290)
Query Neighborhood Hits	1113	Target Neighborhood Hits	355	Shared Neighborhood Hits	272
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ASZ1_MOUSE
θ value	6.21693e-09 (rank : 302)	NC score	0.428446 (rank : 253)
Query Neighborhood Hits	1113	Target Neighborhood Hits	319	Shared Neighborhood Hits	269
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

LRP8_MOUSE
θ value	6.21693e-09 (rank : 303)	NC score	0.530407 (rank : 151)
Query Neighborhood Hits	1113	Target Neighborhood Hits	385	Shared Neighborhood Hits	303
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

ANKR1_HUMAN
θ value	8.11959e-09 (rank : 304)	NC score	0.428961 (rank : 251)
Query Neighborhood Hits	1113	Target Neighborhood Hits	308	Shared Neighborhood Hits	271
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ANR38_HUMAN
θ value	8.11959e-09 (rank : 305)	NC score	0.383952 (rank : 376)
Query Neighborhood Hits	1113	Target Neighborhood Hits	443	Shared Neighborhood Hits	253
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

LRP4_MOUSE
θ value	8.11959e-09 (rank : 306)	NC score	0.485970 (rank : 182)
Query Neighborhood Hits	1113	Target Neighborhood Hits	351	Shared Neighborhood Hits	285
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

PROZ_MOUSE
θ value	8.11959e-09 (rank : 307)	NC score	0.533354 (rank : 149)
Query Neighborhood Hits	1113	Target Neighborhood Hits	410	Shared Neighborhood Hits	274
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

ANR26_HUMAN
θ value	1.06045e-08 (rank : 308)	NC score	0.230819 (rank : 579)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1614	Shared Neighborhood Hits	328
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

GNPTA_MOUSE
θ value	1.06045e-08 (rank : 309)	NC score	0.151944 (rank : 711)
Query Neighborhood Hits	1113	Target Neighborhood Hits	47	Shared Neighborhood Hits	17
SwissProt Accessions	Q69ZN6, Q3U3K6, Q3US34	Gene names	Gnptab, Gnpta, Kiaa1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

MEGF9_HUMAN
θ value	1.06045e-08 (rank : 310)	NC score	0.569790 (rank : 131)
Query Neighborhood Hits	1113	Target Neighborhood Hits	557	Shared Neighborhood Hits	330
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

ZDH17_HUMAN
θ value	1.06045e-08 (rank : 311)	NC score	0.380160 (rank : 382)
Query Neighborhood Hits	1113	Target Neighborhood Hits	334	Shared Neighborhood Hits	275
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

ASB10_MOUSE
θ value	1.38499e-08 (rank : 312)	NC score	0.430651 (rank : 248)
Query Neighborhood Hits	1113	Target Neighborhood Hits	301	Shared Neighborhood Hits	276
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

FA10_HUMAN
θ value	1.38499e-08 (rank : 313)	NC score	0.311506 (rank : 479)
Query Neighborhood Hits	1113	Target Neighborhood Hits	431	Shared Neighborhood Hits	273
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

IKBA_HUMAN
θ value	1.38499e-08 (rank : 314)	NC score	0.428871 (rank : 252)
Query Neighborhood Hits	1113	Target Neighborhood Hits	280	Shared Neighborhood Hits	272
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

MEGF9_MOUSE
θ value	1.38499e-08 (rank : 315)	NC score	0.543974 (rank : 142)
Query Neighborhood Hits	1113	Target Neighborhood Hits	896	Shared Neighborhood Hits	402
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MIB2_MOUSE
θ value	1.38499e-08 (rank : 316)	NC score	0.404066 (rank : 333)
Query Neighborhood Hits	1113	Target Neighborhood Hits	409	Shared Neighborhood Hits	282
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

NFKB2_HUMAN
θ value	1.38499e-08 (rank : 317)	NC score	0.371427 (rank : 403)
Query Neighborhood Hits	1113	Target Neighborhood Hits	325	Shared Neighborhood Hits	278
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

TNI3K_HUMAN
θ value	1.38499e-08 (rank : 318)	NC score	0.213788 (rank : 609)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1084	Shared Neighborhood Hits	316
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

AN30A_HUMAN
θ value	1.80886e-08 (rank : 319)	NC score	0.301751 (rank : 486)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1119	Shared Neighborhood Hits	302
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ANKR2_MOUSE
θ value	1.80886e-08 (rank : 320)	NC score	0.426945 (rank : 257)
Query Neighborhood Hits	1113	Target Neighborhood Hits	312	Shared Neighborhood Hits	276
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ANR42_HUMAN
θ value	1.80886e-08 (rank : 321)	NC score	0.420992 (rank : 291)
Query Neighborhood Hits	1113	Target Neighborhood Hits	284	Shared Neighborhood Hits	269
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ASB15_MOUSE
θ value	1.80886e-08 (rank : 322)	NC score	0.416448 (rank : 302)
Query Neighborhood Hits	1113	Target Neighborhood Hits	292	Shared Neighborhood Hits	268
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ITB3_HUMAN
θ value	1.80886e-08 (rank : 323)	NC score	0.455821 (rank : 201)
Query Neighborhood Hits	1113	Target Neighborhood Hits	325	Shared Neighborhood Hits	282
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

NTNG2_HUMAN
θ value	1.80886e-08 (rank : 324)	NC score	0.496633 (rank : 177)
Query Neighborhood Hits	1113	Target Neighborhood Hits	276	Shared Neighborhood Hits	252
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

NFKB2_MOUSE
θ value	2.36244e-08 (rank : 325)	NC score	0.358861 (rank : 426)
Query Neighborhood Hits	1113	Target Neighborhood Hits	326	Shared Neighborhood Hits	273
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

NTNG1_MOUSE
θ value	2.36244e-08 (rank : 326)	NC score	0.472382 (rank : 187)
Query Neighborhood Hits	1113	Target Neighborhood Hits	246	Shared Neighborhood Hits	217
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

ANR16_HUMAN
θ value	3.08544e-08 (rank : 327)	NC score	0.438136 (rank : 225)
Query Neighborhood Hits	1113	Target Neighborhood Hits	286	Shared Neighborhood Hits	271
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

ANR25_HUMAN
θ value	3.08544e-08 (rank : 328)	NC score	0.378206 (rank : 389)
Query Neighborhood Hits	1113	Target Neighborhood Hits	350	Shared Neighborhood Hits	263
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

LYAM2_HUMAN
θ value	3.08544e-08 (rank : 329)	NC score	0.362293 (rank : 422)
Query Neighborhood Hits	1113	Target Neighborhood Hits	394	Shared Neighborhood Hits	265
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

ZDH13_MOUSE
θ value	3.08544e-08 (rank : 330)	NC score	0.378612 (rank : 387)
Query Neighborhood Hits	1113	Target Neighborhood Hits	329	Shared Neighborhood Hits	276
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

ZDH17_MOUSE
θ value	3.08544e-08 (rank : 331)	NC score	0.376571 (rank : 392)
Query Neighborhood Hits	1113	Target Neighborhood Hits	328	Shared Neighborhood Hits	270
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

ASB10_HUMAN
θ value	4.0297e-08 (rank : 332)	NC score	0.426295 (rank : 262)
Query Neighborhood Hits	1113	Target Neighborhood Hits	291	Shared Neighborhood Hits	273
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

CSKI2_MOUSE
θ value	4.0297e-08 (rank : 333)	NC score	0.397776 (rank : 347)
Query Neighborhood Hits	1113	Target Neighborhood Hits	812	Shared Neighborhood Hits	370
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

GABP3_MOUSE
θ value	4.0297e-08 (rank : 334)	NC score	0.436651 (rank : 231)
Query Neighborhood Hits	1113	Target Neighborhood Hits	330	Shared Neighborhood Hits	272
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

GRN_MOUSE
θ value	4.0297e-08 (rank : 335)	NC score	0.511991 (rank : 164)
Query Neighborhood Hits	1113	Target Neighborhood Hits	248	Shared Neighborhood Hits	212
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

NAGPA_HUMAN
θ value	4.0297e-08 (rank : 336)	NC score	0.570839 (rank : 130)
Query Neighborhood Hits	1113	Target Neighborhood Hits	282	Shared Neighborhood Hits	263
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

ANKR1_MOUSE
θ value	5.26297e-08 (rank : 337)	NC score	0.425364 (rank : 270)
Query Neighborhood Hits	1113	Target Neighborhood Hits	316	Shared Neighborhood Hits	276
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

EGFL7_HUMAN
θ value	5.26297e-08 (rank : 338)	NC score	0.690190 (rank : 77)
Query Neighborhood Hits	1113	Target Neighborhood Hits	325	Shared Neighborhood Hits	301
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

ANKS1_MOUSE
θ value	6.87365e-08 (rank : 339)	NC score	0.405870 (rank : 329)
Query Neighborhood Hits	1113	Target Neighborhood Hits	453	Shared Neighborhood Hits	297
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

NAGPA_MOUSE
θ value	6.87365e-08 (rank : 340)	NC score	0.565621 (rank : 132)
Query Neighborhood Hits	1113	Target Neighborhood Hits	308	Shared Neighborhood Hits	290
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NFKB1_MOUSE
θ value	6.87365e-08 (rank : 341)	NC score	0.374845 (rank : 399)
Query Neighborhood Hits	1113	Target Neighborhood Hits	300	Shared Neighborhood Hits	265
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

ANKR2_HUMAN
θ value	8.97725e-08 (rank : 342)	NC score	0.423506 (rank : 281)
Query Neighborhood Hits	1113	Target Neighborhood Hits	321	Shared Neighborhood Hits	277
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

ANKS6_HUMAN
θ value	8.97725e-08 (rank : 343)	NC score	0.411753 (rank : 319)
Query Neighborhood Hits	1113	Target Neighborhood Hits	411	Shared Neighborhood Hits	296
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

CD248_HUMAN
θ value	8.97725e-08 (rank : 344)	NC score	0.558095 (rank : 136)
Query Neighborhood Hits	1113	Target Neighborhood Hits	679	Shared Neighborhood Hits	376
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CORIN_MOUSE
θ value	8.97725e-08 (rank : 345)	NC score	0.191466 (rank : 635)
Query Neighborhood Hits	1113	Target Neighborhood Hits	451	Shared Neighborhood Hits	228
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

CSKI2_HUMAN
θ value	8.97725e-08 (rank : 346)	NC score	0.395459 (rank : 353)
Query Neighborhood Hits	1113	Target Neighborhood Hits	747	Shared Neighborhood Hits	348
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

FANK1_HUMAN
θ value	8.97725e-08 (rank : 347)	NC score	0.433026 (rank : 243)
Query Neighborhood Hits	1113	Target Neighborhood Hits	326	Shared Neighborhood Hits	284
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

ITB7_HUMAN
θ value	1.17247e-07 (rank : 348)	NC score	0.453666 (rank : 203)
Query Neighborhood Hits	1113	Target Neighborhood Hits	290	Shared Neighborhood Hits	258
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

LYAM3_MOUSE
θ value	1.17247e-07 (rank : 349)	NC score	0.385640 (rank : 370)
Query Neighborhood Hits	1113	Target Neighborhood Hits	390	Shared Neighborhood Hits	262
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

PROC_HUMAN
θ value	1.17247e-07 (rank : 350)	NC score	0.270555 (rank : 520)
Query Neighborhood Hits	1113	Target Neighborhood Hits	406	Shared Neighborhood Hits	259
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

ATRN_MOUSE
θ value	1.53129e-07 (rank : 351)	NC score	0.418740 (rank : 296)
Query Neighborhood Hits	1113	Target Neighborhood Hits	519	Shared Neighborhood Hits	301
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

ITB5_MOUSE
θ value	1.53129e-07 (rank : 352)	NC score	0.473456 (rank : 186)
Query Neighborhood Hits	1113	Target Neighborhood Hits	329	Shared Neighborhood Hits	283
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

OSBL1_HUMAN
θ value	1.53129e-07 (rank : 353)	NC score	0.337414 (rank : 457)
Query Neighborhood Hits	1113	Target Neighborhood Hits	368	Shared Neighborhood Hits	275
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

ASB13_MOUSE
θ value	1.99992e-07 (rank : 354)	NC score	0.410077 (rank : 322)
Query Neighborhood Hits	1113	Target Neighborhood Hits	293	Shared Neighborhood Hits	274
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB7_HUMAN
θ value	1.99992e-07 (rank : 355)	NC score	0.425666 (rank : 268)
Query Neighborhood Hits	1113	Target Neighborhood Hits	296	Shared Neighborhood Hits	272
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_MOUSE
θ value	1.99992e-07 (rank : 356)	NC score	0.425712 (rank : 266)
Query Neighborhood Hits	1113	Target Neighborhood Hits	296	Shared Neighborhood Hits	272
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ATRN_HUMAN
θ value	1.99992e-07 (rank : 357)	NC score	0.417792 (rank : 298)
Query Neighborhood Hits	1113	Target Neighborhood Hits	525	Shared Neighborhood Hits	302
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

MATN4_HUMAN
θ value	1.99992e-07 (rank : 358)	NC score	0.533070 (rank : 150)
Query Neighborhood Hits	1113	Target Neighborhood Hits	287	Shared Neighborhood Hits	237
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

PGCB_MOUSE
θ value	1.99992e-07 (rank : 359)	NC score	0.293136 (rank : 496)
Query Neighborhood Hits	1113	Target Neighborhood Hits	459	Shared Neighborhood Hits	211
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

ANR19_HUMAN
θ value	2.61198e-07 (rank : 360)	NC score	0.406662 (rank : 328)
Query Neighborhood Hits	1113	Target Neighborhood Hits	276	Shared Neighborhood Hits	262
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

CD248_MOUSE
θ value	2.61198e-07 (rank : 361)	NC score	0.558181 (rank : 135)
Query Neighborhood Hits	1113	Target Neighborhood Hits	578	Shared Neighborhood Hits	344
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD2A1_MOUSE
θ value	2.61198e-07 (rank : 362)	NC score	0.394781 (rank : 354)
Query Neighborhood Hits	1113	Target Neighborhood Hits	206	Shared Neighborhood Hits	199
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

CRIM1_HUMAN
θ value	2.61198e-07 (rank : 363)	NC score	0.465605 (rank : 192)
Query Neighborhood Hits	1113	Target Neighborhood Hits	362	Shared Neighborhood Hits	260
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

IKBA_MOUSE
θ value	2.61198e-07 (rank : 364)	NC score	0.421174 (rank : 289)
Query Neighborhood Hits	1113	Target Neighborhood Hits	283	Shared Neighborhood Hits	274
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

ANR12_HUMAN
θ value	3.41135e-07 (rank : 365)	NC score	0.350938 (rank : 435)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1081	Shared Neighborhood Hits	300
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

CDN2D_HUMAN
θ value	3.41135e-07 (rank : 366)	NC score	0.424811 (rank : 273)
Query Neighborhood Hits	1113	Target Neighborhood Hits	268	Shared Neighborhood Hits	261
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

CDN2D_MOUSE
θ value	3.41135e-07 (rank : 367)	NC score	0.426599 (rank : 261)
Query Neighborhood Hits	1113	Target Neighborhood Hits	267	Shared Neighborhood Hits	260
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

CT086_HUMAN
θ value	3.41135e-07 (rank : 368)	NC score	0.415337 (rank : 309)
Query Neighborhood Hits	1113	Target Neighborhood Hits	277	Shared Neighborhood Hits	265
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

GNPTA_HUMAN
θ value	3.41135e-07 (rank : 369)	NC score	0.153856 (rank : 701)
Query Neighborhood Hits	1113	Target Neighborhood Hits	43	Shared Neighborhood Hits	18
SwissProt Accessions	Q3T906, Q3ZQK2, Q6IPW5, Q86TQ2, Q96N13, Q9ULL2	Gene names	GNPTAB, GNPTA, KIAA1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

ITB5_HUMAN
θ value	3.41135e-07 (rank : 370)	NC score	0.458785 (rank : 196)
Query Neighborhood Hits	1113	Target Neighborhood Hits	310	Shared Neighborhood Hits	263
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

POTE8_HUMAN
θ value	3.41135e-07 (rank : 371)	NC score	0.399430 (rank : 341)
Query Neighborhood Hits	1113	Target Neighborhood Hits	337	Shared Neighborhood Hits	278
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

TENN_HUMAN
θ value	3.41135e-07 (rank : 372)	NC score	0.350177 (rank : 439)
Query Neighborhood Hits	1113	Target Neighborhood Hits	453	Shared Neighborhood Hits	281
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

EGFL7_MOUSE
θ value	4.45536e-07 (rank : 373)	NC score	0.680747 (rank : 79)
Query Neighborhood Hits	1113	Target Neighborhood Hits	287	Shared Neighborhood Hits	272
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

NTNG2_MOUSE
θ value	4.45536e-07 (rank : 374)	NC score	0.507927 (rank : 167)
Query Neighborhood Hits	1113	Target Neighborhood Hits	276	Shared Neighborhood Hits	257
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

ADA30_HUMAN
θ value	5.81887e-07 (rank : 375)	NC score	0.167404 (rank : 683)
Query Neighborhood Hits	1113	Target Neighborhood Hits	391	Shared Neighborhood Hits	164
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ANR25_MOUSE
θ value	5.81887e-07 (rank : 376)	NC score	0.367542 (rank : 412)
Query Neighborhood Hits	1113	Target Neighborhood Hits	398	Shared Neighborhood Hits	281
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

ASB13_HUMAN
θ value	5.81887e-07 (rank : 377)	NC score	0.408326 (rank : 326)
Query Neighborhood Hits	1113	Target Neighborhood Hits	293	Shared Neighborhood Hits	275
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ILK_MOUSE
θ value	5.81887e-07 (rank : 378)	NC score	0.248475 (rank : 557)
Query Neighborhood Hits	1113	Target Neighborhood Hits	858	Shared Neighborhood Hits	299
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

KRA47_HUMAN
θ value	5.81887e-07 (rank : 379)	NC score	0.350316 (rank : 438)
Query Neighborhood Hits	1113	Target Neighborhood Hits	204	Shared Neighborhood Hits	162
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

TPA_MOUSE
θ value	5.81887e-07 (rank : 380)	NC score	0.172358 (rank : 662)
Query Neighborhood Hits	1113	Target Neighborhood Hits	335	Shared Neighborhood Hits	186
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

ANR49_MOUSE
θ value	7.59969e-07 (rank : 381)	NC score	0.423420 (rank : 283)
Query Neighborhood Hits	1113	Target Neighborhood Hits	285	Shared Neighborhood Hits	268
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

IKBE_MOUSE
θ value	7.59969e-07 (rank : 382)	NC score	0.421502 (rank : 288)
Query Neighborhood Hits	1113	Target Neighborhood Hits	308	Shared Neighborhood Hits	275
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

KR10C_HUMAN
θ value	7.59969e-07 (rank : 383)	NC score	0.425136 (rank : 272)
Query Neighborhood Hits	1113	Target Neighborhood Hits	219	Shared Neighborhood Hits	181
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KR412_HUMAN
θ value	7.59969e-07 (rank : 384)	NC score	0.335708 (rank : 461)
Query Neighborhood Hits	1113	Target Neighborhood Hits	178	Shared Neighborhood Hits	144
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

OSBL1_MOUSE
θ value	7.59969e-07 (rank : 385)	NC score	0.328904 (rank : 467)
Query Neighborhood Hits	1113	Target Neighborhood Hits	336	Shared Neighborhood Hits	274
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

USH1G_MOUSE
θ value	7.59969e-07 (rank : 386)	NC score	0.386767 (rank : 367)
Query Neighborhood Hits	1113	Target Neighborhood Hits	271	Shared Neighborhood Hits	257
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

AN36A_HUMAN
θ value	9.92553e-07 (rank : 387)	NC score	0.397296 (rank : 348)
Query Neighborhood Hits	1113	Target Neighborhood Hits	271	Shared Neighborhood Hits	260
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ASB1_HUMAN
θ value	9.92553e-07 (rank : 388)	NC score	0.396217 (rank : 350)
Query Neighborhood Hits	1113	Target Neighborhood Hits	291	Shared Neighborhood Hits	264
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

CO6_HUMAN
θ value	9.92553e-07 (rank : 389)	NC score	0.217507 (rank : 602)
Query Neighborhood Hits	1113	Target Neighborhood Hits	331	Shared Neighborhood Hits	188
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

IKBE_HUMAN
θ value	9.92553e-07 (rank : 390)	NC score	0.419839 (rank : 294)
Query Neighborhood Hits	1113	Target Neighborhood Hits	288	Shared Neighborhood Hits	270
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

ILK1_HUMAN
θ value	9.92553e-07 (rank : 391)	NC score	0.249588 (rank : 555)
Query Neighborhood Hits	1113	Target Neighborhood Hits	857	Shared Neighborhood Hits	300
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK2_HUMAN
θ value	9.92553e-07 (rank : 392)	NC score	0.258642 (rank : 538)
Query Neighborhood Hits	1113	Target Neighborhood Hits	848	Shared Neighborhood Hits	300
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

ITB3_MOUSE
θ value	9.92553e-07 (rank : 393)	NC score	0.435225 (rank : 238)
Query Neighborhood Hits	1113	Target Neighborhood Hits	319	Shared Neighborhood Hits	272
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

MATN4_MOUSE
θ value	9.92553e-07 (rank : 394)	NC score	0.505727 (rank : 170)
Query Neighborhood Hits	1113	Target Neighborhood Hits	277	Shared Neighborhood Hits	230
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

ANR49_HUMAN
θ value	1.29631e-06 (rank : 395)	NC score	0.423989 (rank : 278)
Query Neighborhood Hits	1113	Target Neighborhood Hits	282	Shared Neighborhood Hits	266
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

BARD1_HUMAN
θ value	1.29631e-06 (rank : 396)	NC score	0.382860 (rank : 378)
Query Neighborhood Hits	1113	Target Neighborhood Hits	427	Shared Neighborhood Hits	282
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

GIT2_MOUSE
θ value	1.29631e-06 (rank : 397)	NC score	0.263047 (rank : 529)
Query Neighborhood Hits	1113	Target Neighborhood Hits	323	Shared Neighborhood Hits	249
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

ITB2_MOUSE
θ value	1.29631e-06 (rank : 398)	NC score	0.448457 (rank : 209)
Query Neighborhood Hits	1113	Target Neighborhood Hits	326	Shared Neighborhood Hits	283
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

VWF_HUMAN
θ value	1.29631e-06 (rank : 399)	NC score	0.307571 (rank : 482)
Query Neighborhood Hits	1113	Target Neighborhood Hits	396	Shared Neighborhood Hits	263
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

VWF_MOUSE
θ value	1.29631e-06 (rank : 400)	NC score	0.278137 (rank : 510)
Query Neighborhood Hits	1113	Target Neighborhood Hits	381	Shared Neighborhood Hits	247
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ASB1_MOUSE
θ value	1.69304e-06 (rank : 401)	NC score	0.394258 (rank : 355)
Query Neighborhood Hits	1113	Target Neighborhood Hits	292	Shared Neighborhood Hits	262
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

TEFF2_HUMAN
θ value	1.69304e-06 (rank : 402)	NC score	0.325707 (rank : 469)
Query Neighborhood Hits	1113	Target Neighborhood Hits	211	Shared Neighborhood Hits	156
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

USH1G_HUMAN
θ value	1.69304e-06 (rank : 403)	NC score	0.386332 (rank : 368)
Query Neighborhood Hits	1113	Target Neighborhood Hits	267	Shared Neighborhood Hits	256
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

ASB11_HUMAN
θ value	2.21117e-06 (rank : 404)	NC score	0.388536 (rank : 366)
Query Neighborhood Hits	1113	Target Neighborhood Hits	271	Shared Neighborhood Hits	255
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

CLPB_MOUSE
θ value	2.21117e-06 (rank : 405)	NC score	0.366689 (rank : 415)
Query Neighborhood Hits	1113	Target Neighborhood Hits	289	Shared Neighborhood Hits	246
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

ELTD1_HUMAN
θ value	2.21117e-06 (rank : 406)	NC score	0.383152 (rank : 377)
Query Neighborhood Hits	1113	Target Neighborhood Hits	269	Shared Neighborhood Hits	188
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

KR102_HUMAN
θ value	2.21117e-06 (rank : 407)	NC score	0.468903 (rank : 191)
Query Neighborhood Hits	1113	Target Neighborhood Hits	264	Shared Neighborhood Hits	219
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR10A_HUMAN
θ value	2.21117e-06 (rank : 408)	NC score	0.353171 (rank : 431)
Query Neighborhood Hits	1113	Target Neighborhood Hits	232	Shared Neighborhood Hits	187
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

LAMA4_HUMAN
θ value	2.21117e-06 (rank : 409)	NC score	0.403970 (rank : 334)
Query Neighborhood Hits	1113	Target Neighborhood Hits	708	Shared Neighborhood Hits	245
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

NET4_HUMAN
θ value	2.21117e-06 (rank : 410)	NC score	0.347656 (rank : 440)
Query Neighborhood Hits	1113	Target Neighborhood Hits	191	Shared Neighborhood Hits	161
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

PGCB_HUMAN
θ value	2.21117e-06 (rank : 411)	NC score	0.274094 (rank : 516)
Query Neighborhood Hits	1113	Target Neighborhood Hits	478	Shared Neighborhood Hits	212
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

GIT1_MOUSE
θ value	2.88788e-06 (rank : 412)	NC score	0.262510 (rank : 530)
Query Neighborhood Hits	1113	Target Neighborhood Hits	341	Shared Neighborhood Hits	243
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

GRN_HUMAN
θ value	2.88788e-06 (rank : 413)	NC score	0.502191 (rank : 174)
Query Neighborhood Hits	1113	Target Neighborhood Hits	268	Shared Neighborhood Hits	216
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

LYAM2_MOUSE
θ value	2.88788e-06 (rank : 414)	NC score	0.360206 (rank : 424)
Query Neighborhood Hits	1113	Target Neighborhood Hits	420	Shared Neighborhood Hits	287
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

ADA21_MOUSE
θ value	3.77169e-06 (rank : 415)	NC score	0.161921 (rank : 688)
Query Neighborhood Hits	1113	Target Neighborhood Hits	172	Shared Neighborhood Hits	138
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

ANKR5_MOUSE
θ value	3.77169e-06 (rank : 416)	NC score	0.405839 (rank : 330)
Query Neighborhood Hits	1113	Target Neighborhood Hits	298	Shared Neighborhood Hits	274
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANR39_HUMAN
θ value	3.77169e-06 (rank : 417)	NC score	0.423692 (rank : 280)
Query Neighborhood Hits	1113	Target Neighborhood Hits	285	Shared Neighborhood Hits	274
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

MPP8_HUMAN
θ value	3.77169e-06 (rank : 418)	NC score	0.337785 (rank : 456)
Query Neighborhood Hits	1113	Target Neighborhood Hits	948	Shared Neighborhood Hits	276
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

ADA22_HUMAN
θ value	4.92598e-06 (rank : 419)	NC score	0.160469 (rank : 693)
Query Neighborhood Hits	1113	Target Neighborhood Hits	211	Shared Neighborhood Hits	154
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ANKR7_HUMAN
θ value	4.92598e-06 (rank : 420)	NC score	0.420051 (rank : 293)
Query Neighborhood Hits	1113	Target Neighborhood Hits	286	Shared Neighborhood Hits	269
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

ANR41_HUMAN
θ value	4.92598e-06 (rank : 421)	NC score	0.393240 (rank : 356)
Query Neighborhood Hits	1113	Target Neighborhood Hits	332	Shared Neighborhood Hits	256
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

FANK1_MOUSE
θ value	4.92598e-06 (rank : 422)	NC score	0.425769 (rank : 265)
Query Neighborhood Hits	1113	Target Neighborhood Hits	325	Shared Neighborhood Hits	282
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

KRIT1_HUMAN
θ value	4.92598e-06 (rank : 423)	NC score	0.340516 (rank : 451)
Query Neighborhood Hits	1113	Target Neighborhood Hits	258	Shared Neighborhood Hits	216
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

MMRN1_HUMAN
θ value	4.92598e-06 (rank : 424)	NC score	0.260020 (rank : 533)
Query Neighborhood Hits	1113	Target Neighborhood Hits	636	Shared Neighborhood Hits	191
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

TEFF2_MOUSE
θ value	4.92598e-06 (rank : 425)	NC score	0.326733 (rank : 468)
Query Neighborhood Hits	1113	Target Neighborhood Hits	214	Shared Neighborhood Hits	158
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

ADAM8_MOUSE
θ value	6.43352e-06 (rank : 426)	NC score	0.221084 (rank : 592)
Query Neighborhood Hits	1113	Target Neighborhood Hits	326	Shared Neighborhood Hits	230
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

ASB6_MOUSE
θ value	6.43352e-06 (rank : 427)	NC score	0.389339 (rank : 365)
Query Neighborhood Hits	1113	Target Neighborhood Hits	264	Shared Neighborhood Hits	246
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

CDN2C_HUMAN
θ value	6.43352e-06 (rank : 428)	NC score	0.425688 (rank : 267)
Query Neighborhood Hits	1113	Target Neighborhood Hits	262	Shared Neighborhood Hits	255
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

CO7_HUMAN
θ value	6.43352e-06 (rank : 429)	NC score	0.217643 (rank : 601)
Query Neighborhood Hits	1113	Target Neighborhood Hits	278	Shared Neighborhood Hits	153
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

ITB7_MOUSE
θ value	6.43352e-06 (rank : 430)	NC score	0.451232 (rank : 206)
Query Neighborhood Hits	1113	Target Neighborhood Hits	277	Shared Neighborhood Hits	245
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

ADA22_MOUSE
θ value	8.40245e-06 (rank : 431)	NC score	0.170214 (rank : 672)
Query Neighborhood Hits	1113	Target Neighborhood Hits	225	Shared Neighborhood Hits	164
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

CDN2B_MOUSE
θ value	8.40245e-06 (rank : 432)	NC score	0.368777 (rank : 409)
Query Neighborhood Hits	1113	Target Neighborhood Hits	201	Shared Neighborhood Hits	197
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

KR108_HUMAN
θ value	8.40245e-06 (rank : 433)	NC score	0.424122 (rank : 277)
Query Neighborhood Hits	1113	Target Neighborhood Hits	226	Shared Neighborhood Hits	181
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KRA53_HUMAN
θ value	8.40245e-06 (rank : 434)	NC score	0.609166 (rank : 111)
Query Neighborhood Hits	1113	Target Neighborhood Hits	331	Shared Neighborhood Hits	269
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

ANR11_HUMAN
θ value	1.09739e-05 (rank : 435)	NC score	0.364278 (rank : 418)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1289	Shared Neighborhood Hits	364
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

KR105_HUMAN
θ value	1.09739e-05 (rank : 436)	NC score	0.460635 (rank : 195)
Query Neighborhood Hits	1113	Target Neighborhood Hits	271	Shared Neighborhood Hits	218
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KRIT1_MOUSE
θ value	1.09739e-05 (rank : 437)	NC score	0.341178 (rank : 448)
Query Neighborhood Hits	1113	Target Neighborhood Hits	258	Shared Neighborhood Hits	223
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

NCOA6_MOUSE
θ value	1.09739e-05 (rank : 438)	NC score	0.070420 (rank : 880)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1076	Shared Neighborhood Hits	231
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

ASB14_HUMAN
θ value	1.43324e-05 (rank : 439)	NC score	0.295396 (rank : 493)
Query Neighborhood Hits	1113	Target Neighborhood Hits	187	Shared Neighborhood Hits	173
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

CDN2B_HUMAN
θ value	1.43324e-05 (rank : 440)	NC score	0.359733 (rank : 425)
Query Neighborhood Hits	1113	Target Neighborhood Hits	196	Shared Neighborhood Hits	193
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

HHIP_HUMAN
θ value	1.43324e-05 (rank : 441)	NC score	0.536959 (rank : 146)
Query Neighborhood Hits	1113	Target Neighborhood Hits	249	Shared Neighborhood Hits	240
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

KRA93_HUMAN
θ value	1.43324e-05 (rank : 442)	NC score	0.376114 (rank : 396)
Query Neighborhood Hits	1113	Target Neighborhood Hits	203	Shared Neighborhood Hits	160
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

LAMA3_HUMAN
θ value	1.43324e-05 (rank : 443)	NC score	0.416356 (rank : 304)
Query Neighborhood Hits	1113	Target Neighborhood Hits	760	Shared Neighborhood Hits	279
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

MEP1A_HUMAN
θ value	1.43324e-05 (rank : 444)	NC score	0.225369 (rank : 587)
Query Neighborhood Hits	1113	Target Neighborhood Hits	162	Shared Neighborhood Hits	138
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

ACBD6_MOUSE
θ value	1.87187e-05 (rank : 445)	NC score	0.400556 (rank : 340)
Query Neighborhood Hits	1113	Target Neighborhood Hits	305	Shared Neighborhood Hits	273
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ADA33_MOUSE
θ value	1.87187e-05 (rank : 446)	NC score	0.174084 (rank : 660)
Query Neighborhood Hits	1113	Target Neighborhood Hits	231	Shared Neighborhood Hits	181
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ANR39_MOUSE
θ value	2.44474e-05 (rank : 447)	NC score	0.417373 (rank : 299)
Query Neighborhood Hits	1113	Target Neighborhood Hits	284	Shared Neighborhood Hits	272
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ASB4_MOUSE
θ value	2.44474e-05 (rank : 448)	NC score	0.399189 (rank : 342)
Query Neighborhood Hits	1113	Target Neighborhood Hits	265	Shared Neighborhood Hits	253
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

GIT1_HUMAN
θ value	2.44474e-05 (rank : 449)	NC score	0.260355 (rank : 532)
Query Neighborhood Hits	1113	Target Neighborhood Hits	336	Shared Neighborhood Hits	242
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

KR101_HUMAN
θ value	2.44474e-05 (rank : 450)	NC score	0.496929 (rank : 176)
Query Neighborhood Hits	1113	Target Neighborhood Hits	261	Shared Neighborhood Hits	207
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KRA58_HUMAN
θ value	2.44474e-05 (rank : 451)	NC score	0.582612 (rank : 123)
Query Neighborhood Hits	1113	Target Neighborhood Hits	324	Shared Neighborhood Hits	256
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

MEP1A_MOUSE
θ value	2.44474e-05 (rank : 452)	NC score	0.231491 (rank : 577)
Query Neighborhood Hits	1113	Target Neighborhood Hits	166	Shared Neighborhood Hits	136
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

NRG2_MOUSE
θ value	2.44474e-05 (rank : 453)	NC score	0.220176 (rank : 594)
Query Neighborhood Hits	1113	Target Neighborhood Hits	392	Shared Neighborhood Hits	140
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

TPA_HUMAN
θ value	2.44474e-05 (rank : 454)	NC score	0.171650 (rank : 664)
Query Neighborhood Hits	1113	Target Neighborhood Hits	324	Shared Neighborhood Hits	175
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

ANRA2_MOUSE
θ value	3.19293e-05 (rank : 455)	NC score	0.396371 (rank : 349)
Query Neighborhood Hits	1113	Target Neighborhood Hits	287	Shared Neighborhood Hits	264
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ASB4_HUMAN
θ value	3.19293e-05 (rank : 456)	NC score	0.398030 (rank : 345)
Query Neighborhood Hits	1113	Target Neighborhood Hits	264	Shared Neighborhood Hits	253
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

LAMA4_MOUSE
θ value	3.19293e-05 (rank : 457)	NC score	0.425916 (rank : 263)
Query Neighborhood Hits	1113	Target Neighborhood Hits	584	Shared Neighborhood Hits	239
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

ZAN_HUMAN
θ value	3.19293e-05 (rank : 458)	NC score	0.352422 (rank : 432)
Query Neighborhood Hits	1113	Target Neighborhood Hits	679	Shared Neighborhood Hits	350
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ACBD6_HUMAN
θ value	4.1701e-05 (rank : 459)	NC score	0.397946 (rank : 346)
Query Neighborhood Hits	1113	Target Neighborhood Hits	304	Shared Neighborhood Hits	273
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

KRA92_HUMAN
θ value	4.1701e-05 (rank : 460)	NC score	0.345504 (rank : 442)
Query Neighborhood Hits	1113	Target Neighborhood Hits	198	Shared Neighborhood Hits	153
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

NFX1_HUMAN
θ value	4.1701e-05 (rank : 461)	NC score	0.343058 (rank : 447)
Query Neighborhood Hits	1113	Target Neighborhood Hits	405	Shared Neighborhood Hits	199
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

ADA21_HUMAN
θ value	7.1131e-05 (rank : 462)	NC score	0.152569 (rank : 707)
Query Neighborhood Hits	1113	Target Neighborhood Hits	181	Shared Neighborhood Hits	144
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

ANKR5_HUMAN
θ value	7.1131e-05 (rank : 463)	NC score	0.398106 (rank : 344)
Query Neighborhood Hits	1113	Target Neighborhood Hits	297	Shared Neighborhood Hits	271
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANRA2_HUMAN
θ value	7.1131e-05 (rank : 464)	NC score	0.393224 (rank : 357)
Query Neighborhood Hits	1113	Target Neighborhood Hits	288	Shared Neighborhood Hits	265
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

CDN2C_MOUSE
θ value	7.1131e-05 (rank : 465)	NC score	0.420610 (rank : 292)
Query Neighborhood Hits	1113	Target Neighborhood Hits	270	Shared Neighborhood Hits	260
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

NRG2_HUMAN
θ value	7.1131e-05 (rank : 466)	NC score	0.188060 (rank : 641)
Query Neighborhood Hits	1113	Target Neighborhood Hits	419	Shared Neighborhood Hits	138
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

ANR46_HUMAN
θ value	9.29e-05 (rank : 467)	NC score	0.412470 (rank : 317)
Query Neighborhood Hits	1113	Target Neighborhood Hits	281	Shared Neighborhood Hits	269
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

GLSK_HUMAN
θ value	9.29e-05 (rank : 468)	NC score	0.227005 (rank : 584)
Query Neighborhood Hits	1113	Target Neighborhood Hits	204	Shared Neighborhood Hits	182
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

IKBB_HUMAN
θ value	9.29e-05 (rank : 469)	NC score	0.396006 (rank : 351)
Query Neighborhood Hits	1113	Target Neighborhood Hits	284	Shared Neighborhood Hits	270
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

LYAM1_MOUSE
θ value	9.29e-05 (rank : 470)	NC score	0.301619 (rank : 487)
Query Neighborhood Hits	1113	Target Neighborhood Hits	332	Shared Neighborhood Hits	212
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

PGCA_HUMAN
θ value	9.29e-05 (rank : 471)	NC score	0.218550 (rank : 599)
Query Neighborhood Hits	1113	Target Neighborhood Hits	821	Shared Neighborhood Hits	233
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

RERE_MOUSE
θ value	9.29e-05 (rank : 472)	NC score	0.048364 (rank : 1026)
Query Neighborhood Hits	1113	Target Neighborhood Hits	785	Shared Neighborhood Hits	138
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

ANR46_MOUSE
θ value	0.000121331 (rank : 473)	NC score	0.411821 (rank : 318)
Query Neighborhood Hits	1113	Target Neighborhood Hits	274	Shared Neighborhood Hits	263
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

HHIP_MOUSE
θ value	0.000121331 (rank : 474)	NC score	0.515698 (rank : 161)
Query Neighborhood Hits	1113	Target Neighborhood Hits	219	Shared Neighborhood Hits	211
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

KR414_HUMAN
θ value	0.000121331 (rank : 475)	NC score	0.350650 (rank : 437)
Query Neighborhood Hits	1113	Target Neighborhood Hits	199	Shared Neighborhood Hits	162
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

NET4_MOUSE
θ value	0.000121331 (rank : 476)	NC score	0.340499 (rank : 452)
Query Neighborhood Hits	1113	Target Neighborhood Hits	180	Shared Neighborhood Hits	158
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

ADA19_HUMAN
θ value	0.000158464 (rank : 477)	NC score	0.189506 (rank : 639)
Query Neighborhood Hits	1113	Target Neighborhood Hits	381	Shared Neighborhood Hits	232
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ASB5_HUMAN
θ value	0.000158464 (rank : 478)	NC score	0.382753 (rank : 379)
Query Neighborhood Hits	1113	Target Neighborhood Hits	283	Shared Neighborhood Hits	264
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

CNTP3_HUMAN
θ value	0.000158464 (rank : 479)	NC score	0.236727 (rank : 573)
Query Neighborhood Hits	1113	Target Neighborhood Hits	195	Shared Neighborhood Hits	136
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

KR10B_HUMAN
θ value	0.000158464 (rank : 480)	NC score	0.412807 (rank : 316)
Query Neighborhood Hits	1113	Target Neighborhood Hits	269	Shared Neighborhood Hits	214
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

PGH2_HUMAN
θ value	0.000158464 (rank : 481)	NC score	0.214426 (rank : 608)
Query Neighborhood Hits	1113	Target Neighborhood Hits	103	Shared Neighborhood Hits	93
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

ANKY2_MOUSE
θ value	0.00020696 (rank : 482)	NC score	0.355435 (rank : 428)
Query Neighborhood Hits	1113	Target Neighborhood Hits	316	Shared Neighborhood Hits	256
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANS4B_HUMAN
θ value	0.00020696 (rank : 483)	NC score	0.377757 (rank : 391)
Query Neighborhood Hits	1113	Target Neighborhood Hits	289	Shared Neighborhood Hits	254
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ASB11_MOUSE
θ value	0.00020696 (rank : 484)	NC score	0.382491 (rank : 380)
Query Neighborhood Hits	1113	Target Neighborhood Hits	271	Shared Neighborhood Hits	252
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

C1RA_MOUSE
θ value	0.00020696 (rank : 485)	NC score	0.170669 (rank : 670)
Query Neighborhood Hits	1113	Target Neighborhood Hits	379	Shared Neighborhood Hits	178
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1RB_MOUSE
θ value	0.00020696 (rank : 486)	NC score	0.167986 (rank : 680)
Query Neighborhood Hits	1113	Target Neighborhood Hits	380	Shared Neighborhood Hits	177
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

CNTP4_MOUSE
θ value	0.00020696 (rank : 487)	NC score	0.247585 (rank : 560)
Query Neighborhood Hits	1113	Target Neighborhood Hits	193	Shared Neighborhood Hits	147
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

KRA44_HUMAN
θ value	0.00020696 (rank : 488)	NC score	0.369028 (rank : 408)
Query Neighborhood Hits	1113	Target Neighborhood Hits	162	Shared Neighborhood Hits	130
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KRA94_HUMAN
θ value	0.00020696 (rank : 489)	NC score	0.376175 (rank : 395)
Query Neighborhood Hits	1113	Target Neighborhood Hits	204	Shared Neighborhood Hits	173
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

CENG3_HUMAN
θ value	0.000270298 (rank : 490)	NC score	0.170768 (rank : 669)
Query Neighborhood Hits	1113	Target Neighborhood Hits	455	Shared Neighborhood Hits	228
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_MOUSE
θ value	0.000270298 (rank : 491)	NC score	0.170525 (rank : 671)
Query Neighborhood Hits	1113	Target Neighborhood Hits	467	Shared Neighborhood Hits	229
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

ITB8_HUMAN
θ value	0.000270298 (rank : 492)	NC score	0.372505 (rank : 402)
Query Neighborhood Hits	1113	Target Neighborhood Hits	280	Shared Neighborhood Hits	234
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

KRA45_HUMAN
θ value	0.000270298 (rank : 493)	NC score	0.361837 (rank : 423)
Query Neighborhood Hits	1113	Target Neighborhood Hits	194	Shared Neighborhood Hits	158
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

LYAM1_HUMAN
θ value	0.000270298 (rank : 494)	NC score	0.293970 (rank : 494)
Query Neighborhood Hits	1113	Target Neighborhood Hits	315	Shared Neighborhood Hits	208
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

MFGM_HUMAN
θ value	0.000270298 (rank : 495)	NC score	0.246658 (rank : 562)
Query Neighborhood Hits	1113	Target Neighborhood Hits	150	Shared Neighborhood Hits	129
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

VASN_HUMAN
θ value	0.000270298 (rank : 496)	NC score	0.163427 (rank : 687)
Query Neighborhood Hits	1113	Target Neighborhood Hits	449	Shared Neighborhood Hits	149
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

ANR10_MOUSE
θ value	0.00035302 (rank : 497)	NC score	0.390706 (rank : 362)
Query Neighborhood Hits	1113	Target Neighborhood Hits	273	Shared Neighborhood Hits	261
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ASB6_HUMAN
θ value	0.00035302 (rank : 498)	NC score	0.378473 (rank : 388)
Query Neighborhood Hits	1113	Target Neighborhood Hits	256	Shared Neighborhood Hits	248
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

CENB5_HUMAN
θ value	0.00035302 (rank : 499)	NC score	0.270620 (rank : 519)
Query Neighborhood Hits	1113	Target Neighborhood Hits	395	Shared Neighborhood Hits	262
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

KR109_HUMAN
θ value	0.00035302 (rank : 500)	NC score	0.425774 (rank : 264)
Query Neighborhood Hits	1113	Target Neighborhood Hits	226	Shared Neighborhood Hits	191
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KRA59_HUMAN
θ value	0.000461057 (rank : 501)	NC score	0.527609 (rank : 153)
Query Neighborhood Hits	1113	Target Neighborhood Hits	310	Shared Neighborhood Hits	236
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

PDC6I_MOUSE
θ value	0.000461057 (rank : 502)	NC score	0.047630 (rank : 1028)
Query Neighborhood Hits	1113	Target Neighborhood Hits	275	Shared Neighborhood Hits	54
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

ADAM2_MOUSE
θ value	0.000602161 (rank : 503)	NC score	0.169554 (rank : 675)
Query Neighborhood Hits	1113	Target Neighborhood Hits	209	Shared Neighborhood Hits	166
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

ANKY2_HUMAN
θ value	0.000602161 (rank : 504)	NC score	0.365754 (rank : 416)
Query Neighborhood Hits	1113	Target Neighborhood Hits	306	Shared Neighborhood Hits	256
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR10_HUMAN
θ value	0.000602161 (rank : 505)	NC score	0.392763 (rank : 359)
Query Neighborhood Hits	1113	Target Neighborhood Hits	289	Shared Neighborhood Hits	262
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANS4B_MOUSE
θ value	0.000602161 (rank : 506)	NC score	0.370536 (rank : 404)
Query Neighborhood Hits	1113	Target Neighborhood Hits	294	Shared Neighborhood Hits	250
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ST14_MOUSE
θ value	0.000602161 (rank : 507)	NC score	0.168560 (rank : 679)
Query Neighborhood Hits	1113	Target Neighborhood Hits	419	Shared Neighborhood Hits	212
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

NRG1_HUMAN
θ value	0.000786445 (rank : 508)	NC score	0.221129 (rank : 591)
Query Neighborhood Hits	1113	Target Neighborhood Hits	285	Shared Neighborhood Hits	113
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

POT14_HUMAN
θ value	0.000786445 (rank : 509)	NC score	0.354950 (rank : 429)
Query Neighborhood Hits	1113	Target Neighborhood Hits	403	Shared Neighborhood Hits	270
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

POT22_HUMAN
θ value	0.000786445 (rank : 510)	NC score	0.341109 (rank : 449)
Query Neighborhood Hits	1113	Target Neighborhood Hits	266	Shared Neighborhood Hits	253
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

TRPV5_HUMAN
θ value	0.000786445 (rank : 511)	NC score	0.264469 (rank : 526)
Query Neighborhood Hits	1113	Target Neighborhood Hits	261	Shared Neighborhood Hits	219
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

ADAM8_HUMAN
θ value	0.00102713 (rank : 512)	NC score	0.203025 (rank : 618)
Query Neighborhood Hits	1113	Target Neighborhood Hits	327	Shared Neighborhood Hits	247
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ASB5_MOUSE
θ value	0.00102713 (rank : 513)	NC score	0.379450 (rank : 385)
Query Neighborhood Hits	1113	Target Neighborhood Hits	266	Shared Neighborhood Hits	255
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

CD2A1_HUMAN
θ value	0.00102713 (rank : 514)	NC score	0.336274 (rank : 459)
Query Neighborhood Hits	1113	Target Neighborhood Hits	196	Shared Neighborhood Hits	190
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

CO8B_MOUSE
θ value	0.00102713 (rank : 515)	NC score	0.195219 (rank : 627)
Query Neighborhood Hits	1113	Target Neighborhood Hits	224	Shared Neighborhood Hits	133
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

KRA99_HUMAN
θ value	0.00102713 (rank : 516)	NC score	0.330442 (rank : 465)
Query Neighborhood Hits	1113	Target Neighborhood Hits	173	Shared Neighborhood Hits	141
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

PERT_MOUSE
θ value	0.00102713 (rank : 517)	NC score	0.279270 (rank : 506)
Query Neighborhood Hits	1113	Target Neighborhood Hits	221	Shared Neighborhood Hits	165
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

AD26A_MOUSE
θ value	0.00134147 (rank : 518)	NC score	0.121442 (rank : 767)
Query Neighborhood Hits	1113	Target Neighborhood Hits	165	Shared Neighborhood Hits	129
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

ADA23_HUMAN
θ value	0.00134147 (rank : 519)	NC score	0.204933 (rank : 615)
Query Neighborhood Hits	1113	Target Neighborhood Hits	235	Shared Neighborhood Hits	189
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

CN032_HUMAN
θ value	0.00134147 (rank : 520)	NC score	0.053169 (rank : 995)
Query Neighborhood Hits	1113	Target Neighborhood Hits	267	Shared Neighborhood Hits	57
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

EMR3_HUMAN
θ value	0.00134147 (rank : 521)	NC score	0.302483 (rank : 484)
Query Neighborhood Hits	1113	Target Neighborhood Hits	245	Shared Neighborhood Hits	163
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

MTPN_HUMAN
θ value	0.00134147 (rank : 522)	NC score	0.403325 (rank : 335)
Query Neighborhood Hits	1113	Target Neighborhood Hits	269	Shared Neighborhood Hits	259
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

MTPN_MOUSE
θ value	0.00134147 (rank : 523)	NC score	0.404746 (rank : 332)
Query Neighborhood Hits	1113	Target Neighborhood Hits	269	Shared Neighborhood Hits	259
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

NRX1A_MOUSE
θ value	0.00134147 (rank : 524)	NC score	0.275751 (rank : 514)
Query Neighborhood Hits	1113	Target Neighborhood Hits	164	Shared Neighborhood Hits	137
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

PGH1_MOUSE
θ value	0.00134147 (rank : 525)	NC score	0.201726 (rank : 621)
Query Neighborhood Hits	1113	Target Neighborhood Hits	100	Shared Neighborhood Hits	85
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

RFXK_HUMAN
θ value	0.00134147 (rank : 526)	NC score	0.389894 (rank : 364)
Query Neighborhood Hits	1113	Target Neighborhood Hits	282	Shared Neighborhood Hits	261
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

CNTP2_HUMAN
θ value	0.00175202 (rank : 527)	NC score	0.254727 (rank : 547)
Query Neighborhood Hits	1113	Target Neighborhood Hits	199	Shared Neighborhood Hits	151
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP2_MOUSE
θ value	0.00175202 (rank : 528)	NC score	0.257353 (rank : 541)
Query Neighborhood Hits	1113	Target Neighborhood Hits	194	Shared Neighborhood Hits	147
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

KRA42_HUMAN
θ value	0.00175202 (rank : 529)	NC score	0.257542 (rank : 540)
Query Neighborhood Hits	1113	Target Neighborhood Hits	149	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

KRA51_HUMAN
θ value	0.00175202 (rank : 530)	NC score	0.603987 (rank : 113)
Query Neighborhood Hits	1113	Target Neighborhood Hits	288	Shared Neighborhood Hits	227
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

NRX1A_HUMAN
θ value	0.00175202 (rank : 531)	NC score	0.276613 (rank : 511)
Query Neighborhood Hits	1113	Target Neighborhood Hits	170	Shared Neighborhood Hits	138
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

TEX14_MOUSE
θ value	0.00175202 (rank : 532)	NC score	0.191466 (rank : 636)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1333	Shared Neighborhood Hits	305
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TRPV5_MOUSE
θ value	0.00175202 (rank : 533)	NC score	0.266736 (rank : 524)
Query Neighborhood Hits	1113	Target Neighborhood Hits	278	Shared Neighborhood Hits	243
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

ADA12_MOUSE
θ value	0.00228821 (rank : 534)	NC score	0.147192 (rank : 720)
Query Neighborhood Hits	1113	Target Neighborhood Hits	474	Shared Neighborhood Hits	236
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADAM2_HUMAN
θ value	0.00228821 (rank : 535)	NC score	0.152782 (rank : 704)
Query Neighborhood Hits	1113	Target Neighborhood Hits	175	Shared Neighborhood Hits	144
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

ADAM9_MOUSE
θ value	0.00228821 (rank : 536)	NC score	0.182040 (rank : 650)
Query Neighborhood Hits	1113	Target Neighborhood Hits	325	Shared Neighborhood Hits	217
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ANR40_HUMAN
θ value	0.00228821 (rank : 537)	NC score	0.323060 (rank : 472)
Query Neighborhood Hits	1113	Target Neighborhood Hits	224	Shared Neighborhood Hits	203
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

BARD1_MOUSE
θ value	0.00228821 (rank : 538)	NC score	0.373615 (rank : 400)
Query Neighborhood Hits	1113	Target Neighborhood Hits	411	Shared Neighborhood Hits	276
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

C1R_HUMAN
θ value	0.00228821 (rank : 539)	NC score	0.152745 (rank : 705)
Query Neighborhood Hits	1113	Target Neighborhood Hits	364	Shared Neighborhood Hits	168
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

DIAP1_HUMAN
θ value	0.00228821 (rank : 540)	NC score	0.030378 (rank : 1101)
Query Neighborhood Hits	1113	Target Neighborhood Hits	784	Shared Neighborhood Hits	85
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

ADA12_HUMAN
θ value	0.00298849 (rank : 541)	NC score	0.158899 (rank : 694)
Query Neighborhood Hits	1113	Target Neighborhood Hits	224	Shared Neighborhood Hits	161
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA23_MOUSE
θ value	0.00298849 (rank : 542)	NC score	0.198578 (rank : 624)
Query Neighborhood Hits	1113	Target Neighborhood Hits	245	Shared Neighborhood Hits	203
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADAM9_HUMAN
θ value	0.00298849 (rank : 543)	NC score	0.171740 (rank : 663)
Query Neighborhood Hits	1113	Target Neighborhood Hits	243	Shared Neighborhood Hits	186
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

ANR22_HUMAN
θ value	0.00298849 (rank : 544)	NC score	0.402462 (rank : 338)
Query Neighborhood Hits	1113	Target Neighborhood Hits	243	Shared Neighborhood Hits	236
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

CNTP4_HUMAN
θ value	0.00298849 (rank : 545)	NC score	0.239824 (rank : 569)
Query Neighborhood Hits	1113	Target Neighborhood Hits	187	Shared Neighborhood Hits	129
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

IKBB_MOUSE
θ value	0.00298849 (rank : 546)	NC score	0.395853 (rank : 352)
Query Neighborhood Hits	1113	Target Neighborhood Hits	284	Shared Neighborhood Hits	273
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

MAGE1_HUMAN
θ value	0.00298849 (rank : 547)	NC score	0.056826 (rank : 961)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1389	Shared Neighborhood Hits	248
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

NRX2A_HUMAN
θ value	0.00298849 (rank : 548)	NC score	0.263181 (rank : 528)
Query Neighborhood Hits	1113	Target Neighborhood Hits	614	Shared Neighborhood Hits	263
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

ADA18_MOUSE
θ value	0.00390308 (rank : 549)	NC score	0.177861 (rank : 653)
Query Neighborhood Hits	1113	Target Neighborhood Hits	227	Shared Neighborhood Hits	190
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ADA19_MOUSE
θ value	0.00390308 (rank : 550)	NC score	0.189827 (rank : 638)
Query Neighborhood Hits	1113	Target Neighborhood Hits	315	Shared Neighborhood Hits	217
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ANR40_MOUSE
θ value	0.00390308 (rank : 551)	NC score	0.315956 (rank : 474)
Query Neighborhood Hits	1113	Target Neighborhood Hits	228	Shared Neighborhood Hits	202
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

GSCR1_HUMAN
θ value	0.00390308 (rank : 552)	NC score	0.056187 (rank : 965)
Query Neighborhood Hits	1113	Target Neighborhood Hits	674	Shared Neighborhood Hits	139
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

KRA55_HUMAN
θ value	0.00390308 (rank : 553)	NC score	0.511734 (rank : 165)
Query Neighborhood Hits	1113	Target Neighborhood Hits	257	Shared Neighborhood Hits	212
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

TRPV3_MOUSE
θ value	0.00390308 (rank : 554)	NC score	0.149467 (rank : 716)
Query Neighborhood Hits	1113	Target Neighborhood Hits	188	Shared Neighborhood Hits	130
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

WASF3_MOUSE
θ value	0.00390308 (rank : 555)	NC score	0.051738 (rank : 1010)
Query Neighborhood Hits	1113	Target Neighborhood Hits	188	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

ADM1A_MOUSE
θ value	0.00509761 (rank : 556)	NC score	0.161157 (rank : 690)
Query Neighborhood Hits	1113	Target Neighborhood Hits	230	Shared Neighborhood Hits	193
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ARI1A_HUMAN
θ value	0.00509761 (rank : 557)	NC score	0.042977 (rank : 1050)
Query Neighborhood Hits	1113	Target Neighborhood Hits	787	Shared Neighborhood Hits	148
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

CENG1_HUMAN
θ value	0.00509761 (rank : 558)	NC score	0.185416 (rank : 645)
Query Neighborhood Hits	1113	Target Neighborhood Hits	544	Shared Neighborhood Hits	263
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CENG1_MOUSE
θ value	0.00509761 (rank : 559)	NC score	0.182355 (rank : 649)
Query Neighborhood Hits	1113	Target Neighborhood Hits	531	Shared Neighborhood Hits	261
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

EMR4_MOUSE
θ value	0.00509761 (rank : 560)	NC score	0.221859 (rank : 590)
Query Neighborhood Hits	1113	Target Neighborhood Hits	191	Shared Neighborhood Hits	121
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

MUC2_HUMAN
θ value	0.00509761 (rank : 561)	NC score	0.206375 (rank : 614)
Query Neighborhood Hits	1113	Target Neighborhood Hits	906	Shared Neighborhood Hits	273
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PER1_HUMAN
θ value	0.00509761 (rank : 562)	NC score	0.021676 (rank : 1166)
Query Neighborhood Hits	1113	Target Neighborhood Hits	215	Shared Neighborhood Hits	50
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

ST14_HUMAN
θ value	0.00509761 (rank : 563)	NC score	0.169400 (rank : 676)
Query Neighborhood Hits	1113	Target Neighborhood Hits	409	Shared Neighborhood Hits	201
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

UROL1_MOUSE
θ value	0.00509761 (rank : 564)	NC score	0.286992 (rank : 502)
Query Neighborhood Hits	1113	Target Neighborhood Hits	235	Shared Neighborhood Hits	158
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

WASF2_HUMAN
θ value	0.00509761 (rank : 565)	NC score	0.041339 (rank : 1056)
Query Neighborhood Hits	1113	Target Neighborhood Hits	280	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

ADA15_HUMAN
θ value	0.00665767 (rank : 566)	NC score	0.184541 (rank : 647)
Query Neighborhood Hits	1113	Target Neighborhood Hits	288	Shared Neighborhood Hits	221
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

ADA20_HUMAN
θ value	0.00665767 (rank : 567)	NC score	0.113337 (rank : 776)
Query Neighborhood Hits	1113	Target Neighborhood Hits	143	Shared Neighborhood Hits	102
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

ANR33_MOUSE
θ value	0.00665767 (rank : 568)	NC score	0.367200 (rank : 413)
Query Neighborhood Hits	1113	Target Neighborhood Hits	225	Shared Neighborhood Hits	219
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ANR37_HUMAN
θ value	0.00665767 (rank : 569)	NC score	0.362445 (rank : 421)
Query Neighborhood Hits	1113	Target Neighborhood Hits	247	Shared Neighborhood Hits	240
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

ASB12_HUMAN
θ value	0.00665767 (rank : 570)	NC score	0.384893 (rank : 373)
Query Neighborhood Hits	1113	Target Neighborhood Hits	263	Shared Neighborhood Hits	255
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ASB12_MOUSE
θ value	0.00665767 (rank : 571)	NC score	0.381483 (rank : 381)
Query Neighborhood Hits	1113	Target Neighborhood Hits	261	Shared Neighborhood Hits	252
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ASPP1_HUMAN
θ value	0.00665767 (rank : 572)	NC score	0.256804 (rank : 543)
Query Neighborhood Hits	1113	Target Neighborhood Hits	956	Shared Neighborhood Hits	304
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP1_MOUSE
θ value	0.00665767 (rank : 573)	NC score	0.256088 (rank : 546)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1244	Shared Neighborhood Hits	384
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CENB1_HUMAN
θ value	0.00665767 (rank : 574)	NC score	0.272045 (rank : 518)
Query Neighborhood Hits	1113	Target Neighborhood Hits	383	Shared Neighborhood Hits	256
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

KRA98_HUMAN
θ value	0.00665767 (rank : 575)	NC score	0.366712 (rank : 414)
Query Neighborhood Hits	1113	Target Neighborhood Hits	185	Shared Neighborhood Hits	146
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

MUC13_MOUSE
θ value	0.00665767 (rank : 576)	NC score	0.298719 (rank : 490)
Query Neighborhood Hits	1113	Target Neighborhood Hits	447	Shared Neighborhood Hits	211
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

PRP2_MOUSE
θ value	0.00665767 (rank : 577)	NC score	0.059830 (rank : 945)
Query Neighborhood Hits	1113	Target Neighborhood Hits	347	Shared Neighborhood Hits	75
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

TEX14_HUMAN
θ value	0.00665767 (rank : 578)	NC score	0.193899 (rank : 629)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1103	Shared Neighborhood Hits	294
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TRPV6_HUMAN
θ value	0.00665767 (rank : 579)	NC score	0.257307 (rank : 542)
Query Neighborhood Hits	1113	Target Neighborhood Hits	262	Shared Neighborhood Hits	221
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

ADA28_MOUSE
θ value	0.00869519 (rank : 580)	NC score	0.153849 (rank : 702)
Query Neighborhood Hits	1113	Target Neighborhood Hits	241	Shared Neighborhood Hits	179
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ANR33_HUMAN
θ value	0.00869519 (rank : 581)	NC score	0.352263 (rank : 433)
Query Neighborhood Hits	1113	Target Neighborhood Hits	215	Shared Neighborhood Hits	210
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ANR37_MOUSE
θ value	0.00869519 (rank : 582)	NC score	0.351102 (rank : 434)
Query Neighborhood Hits	1113	Target Neighborhood Hits	237	Shared Neighborhood Hits	230
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

C1S_HUMAN
θ value	0.00869519 (rank : 583)	NC score	0.141487 (rank : 734)
Query Neighborhood Hits	1113	Target Neighborhood Hits	359	Shared Neighborhood Hits	167
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

HXA3_MOUSE
θ value	0.00869519 (rank : 584)	NC score	0.003217 (rank : 1264)
Query Neighborhood Hits	1113	Target Neighborhood Hits	558	Shared Neighborhood Hits	63
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

KRA54_HUMAN
θ value	0.00869519 (rank : 585)	NC score	0.504699 (rank : 172)
Query Neighborhood Hits	1113	Target Neighborhood Hits	270	Shared Neighborhood Hits	207
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

LCE1B_HUMAN
θ value	0.00869519 (rank : 586)	NC score	0.325027 (rank : 471)
Query Neighborhood Hits	1113	Target Neighborhood Hits	58	Shared Neighborhood Hits	42
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

NET2_MOUSE
θ value	0.00869519 (rank : 587)	NC score	0.340960 (rank : 450)
Query Neighborhood Hits	1113	Target Neighborhood Hits	193	Shared Neighborhood Hits	162
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

PGH1_HUMAN
θ value	0.00869519 (rank : 588)	NC score	0.175904 (rank : 655)
Query Neighborhood Hits	1113	Target Neighborhood Hits	91	Shared Neighborhood Hits	78
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

PGH2_MOUSE
θ value	0.00869519 (rank : 589)	NC score	0.227531 (rank : 582)
Query Neighborhood Hits	1113	Target Neighborhood Hits	113	Shared Neighborhood Hits	104
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

RSPO3_MOUSE
θ value	0.00869519 (rank : 590)	NC score	0.104761 (rank : 786)
Query Neighborhood Hits	1113	Target Neighborhood Hits	120	Shared Neighborhood Hits	70
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

TRPV3_HUMAN
θ value	0.00869519 (rank : 591)	NC score	0.142342 (rank : 733)
Query Neighborhood Hits	1113	Target Neighborhood Hits	198	Shared Neighborhood Hits	141
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

ABTB2_MOUSE
θ value	0.0113563 (rank : 592)	NC score	0.266144 (rank : 525)
Query Neighborhood Hits	1113	Target Neighborhood Hits	414	Shared Neighborhood Hits	234
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ASPP2_HUMAN
θ value	0.0113563 (rank : 593)	NC score	0.264158 (rank : 527)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1156	Shared Neighborhood Hits	338
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

CLPB_HUMAN
θ value	0.0113563 (rank : 594)	NC score	0.312404 (rank : 478)
Query Neighborhood Hits	1113	Target Neighborhood Hits	265	Shared Neighborhood Hits	232
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

DIAP1_MOUSE
θ value	0.0113563 (rank : 595)	NC score	0.029755 (rank : 1108)
Query Neighborhood Hits	1113	Target Neighborhood Hits	839	Shared Neighborhood Hits	83
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

GNDS_MOUSE
θ value	0.0113563 (rank : 596)	NC score	0.017169 (rank : 1193)
Query Neighborhood Hits	1113	Target Neighborhood Hits	115	Shared Neighborhood Hits	21
SwissProt Accessions	Q03385	Gene names	Ralgds, Rgds
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

KRA57_HUMAN
θ value	0.0113563 (rank : 597)	NC score	0.526984 (rank : 155)
Query Neighborhood Hits	1113	Target Neighborhood Hits	269	Shared Neighborhood Hits	220
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

LCE1F_HUMAN
θ value	0.0113563 (rank : 598)	NC score	0.248149 (rank : 558)
Query Neighborhood Hits	1113	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

RFXK_MOUSE
θ value	0.0113563 (rank : 599)	NC score	0.379955 (rank : 383)
Query Neighborhood Hits	1113	Target Neighborhood Hits	273	Shared Neighborhood Hits	258
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

TLL2_HUMAN
θ value	0.0113563 (rank : 600)	NC score	0.245586 (rank : 563)
Query Neighborhood Hits	1113	Target Neighborhood Hits	241	Shared Neighborhood Hits	184
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

BCOR_HUMAN
θ value	0.0148317 (rank : 601)	NC score	0.333605 (rank : 463)
Query Neighborhood Hits	1113	Target Neighborhood Hits	609	Shared Neighborhood Hits	329
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

BCOR_MOUSE
θ value	0.0148317 (rank : 602)	NC score	0.336882 (rank : 458)
Query Neighborhood Hits	1113	Target Neighborhood Hits	521	Shared Neighborhood Hits	308
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CBP_HUMAN
θ value	0.0148317 (rank : 603)	NC score	0.046047 (rank : 1035)
Query Neighborhood Hits	1113	Target Neighborhood Hits	941	Shared Neighborhood Hits	186
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CENB2_HUMAN
θ value	0.0148317 (rank : 604)	NC score	0.259544 (rank : 535)
Query Neighborhood Hits	1113	Target Neighborhood Hits	425	Shared Neighborhood Hits	249
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CFC1_MOUSE
θ value	0.0148317 (rank : 605)	NC score	0.398171 (rank : 343)
Query Neighborhood Hits	1113	Target Neighborhood Hits	125	Shared Neighborhood Hits	124
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CS1A_MOUSE
θ value	0.0148317 (rank : 606)	NC score	0.146624 (rank : 722)
Query Neighborhood Hits	1113	Target Neighborhood Hits	360	Shared Neighborhood Hits	161
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

EP300_HUMAN
θ value	0.0148317 (rank : 607)	NC score	0.044299 (rank : 1045)
Query Neighborhood Hits	1113	Target Neighborhood Hits	821	Shared Neighborhood Hits	150
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

MASP2_MOUSE
θ value	0.0148317 (rank : 608)	NC score	0.143727 (rank : 730)
Query Neighborhood Hits	1113	Target Neighborhood Hits	382	Shared Neighborhood Hits	172
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

NRG4_HUMAN
θ value	0.0148317 (rank : 609)	NC score	0.232234 (rank : 576)
Query Neighborhood Hits	1113	Target Neighborhood Hits	85	Shared Neighborhood Hits	81
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRX3A_HUMAN
θ value	0.0148317 (rank : 610)	NC score	0.261363 (rank : 531)
Query Neighborhood Hits	1113	Target Neighborhood Hits	164	Shared Neighborhood Hits	144
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

PTN23_HUMAN
θ value	0.0148317 (rank : 611)	NC score	0.019213 (rank : 1179)
Query Neighborhood Hits	1113	Target Neighborhood Hits	646	Shared Neighborhood Hits	97
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

SMDF_HUMAN
θ value	0.0148317 (rank : 612)	NC score	0.232648 (rank : 575)
Query Neighborhood Hits	1113	Target Neighborhood Hits	117	Shared Neighborhood Hits	92
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

TCGAP_HUMAN
θ value	0.0148317 (rank : 613)	NC score	0.039811 (rank : 1065)
Query Neighborhood Hits	1113	Target Neighborhood Hits	872	Shared Neighborhood Hits	186
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

VASN_MOUSE
θ value	0.0148317 (rank : 614)	NC score	0.149383 (rank : 717)
Query Neighborhood Hits	1113	Target Neighborhood Hits	426	Shared Neighborhood Hits	136
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

ZN592_MOUSE
θ value	0.0148317 (rank : 615)	NC score	-0.012732 (rank : 1320)
Query Neighborhood Hits	1113	Target Neighborhood Hits	768	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BHZ4, Q80XM1	Gene names	Znf592, Kiaa0211, Zfp592
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592 (Zfp-592).

ADA29_HUMAN
θ value	0.0193708 (rank : 616)	NC score	0.137794 (rank : 742)
Query Neighborhood Hits	1113	Target Neighborhood Hits	247	Shared Neighborhood Hits	150
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

CFC1_HUMAN
θ value	0.0193708 (rank : 617)	NC score	0.418101 (rank : 297)
Query Neighborhood Hits	1113	Target Neighborhood Hits	148	Shared Neighborhood Hits	146
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CS1B_MOUSE
θ value	0.0193708 (rank : 618)	NC score	0.145462 (rank : 724)
Query Neighborhood Hits	1113	Target Neighborhood Hits	361	Shared Neighborhood Hits	159
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

CTGF_HUMAN
θ value	0.0193708 (rank : 619)	NC score	0.085776 (rank : 824)
Query Neighborhood Hits	1113	Target Neighborhood Hits	128	Shared Neighborhood Hits	62
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

INSRR_MOUSE
θ value	0.0193708 (rank : 620)	NC score	0.044845 (rank : 1042)
Query Neighborhood Hits	1113	Target Neighborhood Hits	961	Shared Neighborhood Hits	159
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

NRG4_MOUSE
θ value	0.0193708 (rank : 621)	NC score	0.225921 (rank : 586)
Query Neighborhood Hits	1113	Target Neighborhood Hits	79	Shared Neighborhood Hits	74
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

PERT_HUMAN
θ value	0.0193708 (rank : 622)	NC score	0.299291 (rank : 489)
Query Neighborhood Hits	1113	Target Neighborhood Hits	221	Shared Neighborhood Hits	172
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

RSPO3_HUMAN
θ value	0.0193708 (rank : 623)	NC score	0.118757 (rank : 772)
Query Neighborhood Hits	1113	Target Neighborhood Hits	128	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

TMPS6_MOUSE
θ value	0.0193708 (rank : 624)	NC score	0.121103 (rank : 768)
Query Neighborhood Hits	1113	Target Neighborhood Hits	341	Shared Neighborhood Hits	155
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TRPV6_MOUSE
θ value	0.0193708 (rank : 625)	NC score	0.293275 (rank : 495)
Query Neighborhood Hits	1113	Target Neighborhood Hits	284	Shared Neighborhood Hits	248
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

WASF2_MOUSE
θ value	0.0193708 (rank : 626)	NC score	0.044860 (rank : 1041)
Query Neighborhood Hits	1113	Target Neighborhood Hits	315	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

ABTB2_HUMAN
θ value	0.0252991 (rank : 627)	NC score	0.272926 (rank : 517)
Query Neighborhood Hits	1113	Target Neighborhood Hits	391	Shared Neighborhood Hits	233
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

CO8B_HUMAN
θ value	0.0252991 (rank : 628)	NC score	0.154220 (rank : 699)
Query Neighborhood Hits	1113	Target Neighborhood Hits	199	Shared Neighborhood Hits	106
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

KRA11_HUMAN
θ value	0.0252991 (rank : 629)	NC score	0.339058 (rank : 454)
Query Neighborhood Hits	1113	Target Neighborhood Hits	155	Shared Neighborhood Hits	134
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

LCE1E_HUMAN
θ value	0.0252991 (rank : 630)	NC score	0.267707 (rank : 522)
Query Neighborhood Hits	1113	Target Neighborhood Hits	53	Shared Neighborhood Hits	35
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

NET2_HUMAN
θ value	0.0252991 (rank : 631)	NC score	0.338645 (rank : 455)
Query Neighborhood Hits	1113	Target Neighborhood Hits	194	Shared Neighborhood Hits	160
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

TDGF1_HUMAN
θ value	0.0252991 (rank : 632)	NC score	0.335813 (rank : 460)
Query Neighborhood Hits	1113	Target Neighborhood Hits	132	Shared Neighborhood Hits	130
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

ADA33_HUMAN
θ value	0.0330416 (rank : 633)	NC score	0.177797 (rank : 654)
Query Neighborhood Hits	1113	Target Neighborhood Hits	264	Shared Neighborhood Hits	197
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ANR32_MOUSE
θ value	0.0330416 (rank : 634)	NC score	0.353812 (rank : 430)
Query Neighborhood Hits	1113	Target Neighborhood Hits	285	Shared Neighborhood Hits	254
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

BCAR1_MOUSE
θ value	0.0330416 (rank : 635)	NC score	0.021853 (rank : 1165)
Query Neighborhood Hits	1113	Target Neighborhood Hits	438	Shared Neighborhood Hits	111
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CIC_MOUSE
θ value	0.0330416 (rank : 636)	NC score	0.030610 (rank : 1099)
Query Neighborhood Hits	1113	Target Neighborhood Hits	742	Shared Neighborhood Hits	156
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

FMN1A_MOUSE
θ value	0.0330416 (rank : 637)	NC score	0.030283 (rank : 1103)
Query Neighborhood Hits	1113	Target Neighborhood Hits	423	Shared Neighborhood Hits	74
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

FMN1B_MOUSE
θ value	0.0330416 (rank : 638)	NC score	0.026261 (rank : 1132)
Query Neighborhood Hits	1113	Target Neighborhood Hits	447	Shared Neighborhood Hits	70
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

IASPP_MOUSE
θ value	0.0330416 (rank : 639)	NC score	0.256670 (rank : 545)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1024	Shared Neighborhood Hits	391
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

KRA15_HUMAN
θ value	0.0330416 (rank : 640)	NC score	0.314524 (rank : 475)
Query Neighborhood Hits	1113	Target Neighborhood Hits	126	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

LCE1C_HUMAN
θ value	0.0330416 (rank : 641)	NC score	0.309770 (rank : 480)
Query Neighborhood Hits	1113	Target Neighborhood Hits	65	Shared Neighborhood Hits	46
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

MEP1B_HUMAN
θ value	0.0330416 (rank : 642)	NC score	0.095009 (rank : 802)
Query Neighborhood Hits	1113	Target Neighborhood Hits	98	Shared Neighborhood Hits	65
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

MUC5B_HUMAN
θ value	0.0330416 (rank : 643)	NC score	0.314013 (rank : 477)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1020	Shared Neighborhood Hits	394
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

TDGF1_MOUSE
θ value	0.0330416 (rank : 644)	NC score	0.385884 (rank : 369)
Query Neighborhood Hits	1113	Target Neighborhood Hits	146	Shared Neighborhood Hits	144
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

TDGF2_HUMAN
θ value	0.0330416 (rank : 645)	NC score	0.329982 (rank : 466)
Query Neighborhood Hits	1113	Target Neighborhood Hits	131	Shared Neighborhood Hits	126
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

ADA24_MOUSE
θ value	0.0431538 (rank : 646)	NC score	0.150973 (rank : 714)
Query Neighborhood Hits	1113	Target Neighborhood Hits	230	Shared Neighborhood Hits	187
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ANR32_HUMAN
θ value	0.0431538 (rank : 647)	NC score	0.357898 (rank : 427)
Query Neighborhood Hits	1113	Target Neighborhood Hits	270	Shared Neighborhood Hits	256
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

IASPP_HUMAN
θ value	0.0431538 (rank : 648)	NC score	0.280842 (rank : 504)
Query Neighborhood Hits	1113	Target Neighborhood Hits	688	Shared Neighborhood Hits	321
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

KRA13_HUMAN
θ value	0.0431538 (rank : 649)	NC score	0.369566 (rank : 406)
Query Neighborhood Hits	1113	Target Neighborhood Hits	144	Shared Neighborhood Hits	123
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

NUMB_MOUSE
θ value	0.0431538 (rank : 650)	NC score	0.030286 (rank : 1102)
Query Neighborhood Hits	1113	Target Neighborhood Hits	91	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QZS3, P70422, Q8CIB1, Q9DC57, Q9QZR1, Q9QZS4	Gene names	Numb
Domain Architecture
Description	Protein numb homolog (m-Numb) (m-Nb).

RAPH1_HUMAN
θ value	0.0431538 (rank : 651)	NC score	0.035448 (rank : 1079)
Query Neighborhood Hits	1113	Target Neighborhood Hits	593	Shared Neighborhood Hits	114
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RBM12_HUMAN
θ value	0.0431538 (rank : 652)	NC score	0.029764 (rank : 1107)
Query Neighborhood Hits	1113	Target Neighborhood Hits	298	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

RBM12_MOUSE
θ value	0.0431538 (rank : 653)	NC score	0.026821 (rank : 1126)
Query Neighborhood Hits	1113	Target Neighborhood Hits	313	Shared Neighborhood Hits	52
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

RECK_MOUSE
θ value	0.0431538 (rank : 654)	NC score	0.189913 (rank : 637)
Query Neighborhood Hits	1113	Target Neighborhood Hits	158	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

TF7L2_HUMAN
θ value	0.0431538 (rank : 655)	NC score	0.024495 (rank : 1141)
Query Neighborhood Hits	1113	Target Neighborhood Hits	119	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NQB0, O00185, Q9NQB1, Q9NQB2, Q9NQB3, Q9NQB4, Q9NQB5, Q9NQB6, Q9NQB7, Q9ULC2	Gene names	TCF7L2, TCF4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (hTCF-4).

TMPS6_HUMAN
θ value	0.0431538 (rank : 656)	NC score	0.127854 (rank : 758)
Query Neighborhood Hits	1113	Target Neighborhood Hits	338	Shared Neighborhood Hits	155
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

ADA25_MOUSE
θ value	0.0563607 (rank : 657)	NC score	0.153102 (rank : 703)
Query Neighborhood Hits	1113	Target Neighborhood Hits	213	Shared Neighborhood Hits	167
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

BMP1_HUMAN
θ value	0.0563607 (rank : 658)	NC score	0.250440 (rank : 553)
Query Neighborhood Hits	1113	Target Neighborhood Hits	233	Shared Neighborhood Hits	183
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	0.0563607 (rank : 659)	NC score	0.252312 (rank : 550)
Query Neighborhood Hits	1113	Target Neighborhood Hits	236	Shared Neighborhood Hits	184
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BRD4_MOUSE
θ value	0.0563607 (rank : 660)	NC score	0.025716 (rank : 1134)
Query Neighborhood Hits	1113	Target Neighborhood Hits	845	Shared Neighborhood Hits	108
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

DDEF2_HUMAN
θ value	0.0563607 (rank : 661)	NC score	0.193409 (rank : 630)
Query Neighborhood Hits	1113	Target Neighborhood Hits	599	Shared Neighborhood Hits	260
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	0.0563607 (rank : 662)	NC score	0.192379 (rank : 633)
Query Neighborhood Hits	1113	Target Neighborhood Hits	625	Shared Neighborhood Hits	266
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DGKI_HUMAN
θ value	0.0563607 (rank : 663)	NC score	0.169119 (rank : 677)
Query Neighborhood Hits	1113	Target Neighborhood Hits	609	Shared Neighborhood Hits	220
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

ENAH_MOUSE
θ value	0.0563607 (rank : 664)	NC score	0.022538 (rank : 1156)
Query Neighborhood Hits	1113	Target Neighborhood Hits	919	Shared Neighborhood Hits	118
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

LRP6_MOUSE
θ value	0.0563607 (rank : 665)	NC score	0.252594 (rank : 549)
Query Neighborhood Hits	1113	Target Neighborhood Hits	232	Shared Neighborhood Hits	173
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

RECK_HUMAN
θ value	0.0563607 (rank : 666)	NC score	0.230942 (rank : 578)
Query Neighborhood Hits	1113	Target Neighborhood Hits	189	Shared Neighborhood Hits	127
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

SPR2D_MOUSE
θ value	0.0563607 (rank : 667)	NC score	0.106012 (rank : 781)
Query Neighborhood Hits	1113	Target Neighborhood Hits	61	Shared Neighborhood Hits	32
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

UROK_MOUSE
θ value	0.0563607 (rank : 668)	NC score	0.104294 (rank : 787)
Query Neighborhood Hits	1113	Target Neighborhood Hits	273	Shared Neighborhood Hits	130
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

AAK1_MOUSE
θ value	0.0736092 (rank : 669)	NC score	0.003736 (rank : 1259)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1051	Shared Neighborhood Hits	128
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

ASB9_HUMAN
θ value	0.0736092 (rank : 670)	NC score	0.375075 (rank : 398)
Query Neighborhood Hits	1113	Target Neighborhood Hits	267	Shared Neighborhood Hits	251
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

CO9_MOUSE
θ value	0.0736092 (rank : 671)	NC score	0.167389 (rank : 684)
Query Neighborhood Hits	1113	Target Neighborhood Hits	153	Shared Neighborhood Hits	105
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

CT012_MOUSE
θ value	0.0736092 (rank : 672)	NC score	0.224364 (rank : 588)
Query Neighborhood Hits	1113	Target Neighborhood Hits	229	Shared Neighborhood Hits	192
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

KRA52_HUMAN
θ value	0.0736092 (rank : 673)	NC score	0.441591 (rank : 219)
Query Neighborhood Hits	1113	Target Neighborhood Hits	236	Shared Neighborhood Hits	194
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

MK07_HUMAN
θ value	0.0736092 (rank : 674)	NC score	-0.002996 (rank : 1302)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1087	Shared Neighborhood Hits	104
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

NET1_MOUSE
θ value	0.0736092 (rank : 675)	NC score	0.291355 (rank : 498)
Query Neighborhood Hits	1113	Target Neighborhood Hits	151	Shared Neighborhood Hits	123
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

OSTF1_HUMAN
θ value	0.0736092 (rank : 676)	NC score	0.289813 (rank : 499)
Query Neighborhood Hits	1113	Target Neighborhood Hits	466	Shared Neighborhood Hits	250
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

PAPPA_HUMAN
θ value	0.0736092 (rank : 677)	NC score	0.110444 (rank : 777)
Query Neighborhood Hits	1113	Target Neighborhood Hits	161	Shared Neighborhood Hits	87
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

SF3A1_MOUSE
θ value	0.0736092 (rank : 678)	NC score	0.028555 (rank : 1117)
Query Neighborhood Hits	1113	Target Neighborhood Hits	198	Shared Neighborhood Hits	39
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

TLX3_MOUSE
θ value	0.0736092 (rank : 679)	NC score	-0.004465 (rank : 1307)
Query Neighborhood Hits	1113	Target Neighborhood Hits	346	Shared Neighborhood Hits	10
SwissProt Accessions	O55144	Gene names	Tlx3, Hox11l2, Rnx, Tlx1l2
Domain Architecture
Description	T-cell leukemia homeobox protein 3 (Homeobox TLX-3) (Homeobox protein Hox-11L2) (Respiratory neuron homeobox protein).

ATS7_HUMAN
θ value	0.0961366 (rank : 680)	NC score	0.060134 (rank : 942)
Query Neighborhood Hits	1113	Target Neighborhood Hits	169	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

CBP_MOUSE
θ value	0.0961366 (rank : 681)	NC score	0.046718 (rank : 1032)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1051	Shared Neighborhood Hits	217
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

DDFL1_MOUSE
θ value	0.0961366 (rank : 682)	NC score	0.219565 (rank : 595)
Query Neighborhood Hits	1113	Target Neighborhood Hits	324	Shared Neighborhood Hits	242
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

GGN_MOUSE
θ value	0.0961366 (rank : 683)	NC score	0.035385 (rank : 1080)
Query Neighborhood Hits	1113	Target Neighborhood Hits	311	Shared Neighborhood Hits	70
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

INSRR_HUMAN
θ value	0.0961366 (rank : 684)	NC score	0.044052 (rank : 1047)
Query Neighborhood Hits	1113	Target Neighborhood Hits	950	Shared Neighborhood Hits	147
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

KR103_HUMAN
θ value	0.0961366 (rank : 685)	NC score	0.339983 (rank : 453)
Query Neighborhood Hits	1113	Target Neighborhood Hits	212	Shared Neighborhood Hits	173
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

LRP6_HUMAN
θ value	0.0961366 (rank : 686)	NC score	0.256774 (rank : 544)
Query Neighborhood Hits	1113	Target Neighborhood Hits	235	Shared Neighborhood Hits	177
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

MINT_MOUSE
θ value	0.0961366 (rank : 687)	NC score	0.028969 (rank : 1114)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1514	Shared Neighborhood Hits	219
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PAP2_HUMAN
θ value	0.0961366 (rank : 688)	NC score	0.081247 (rank : 845)
Query Neighborhood Hits	1113	Target Neighborhood Hits	106	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

PLMN_MOUSE
θ value	0.0961366 (rank : 689)	NC score	0.047168 (rank : 1030)
Query Neighborhood Hits	1113	Target Neighborhood Hits	208	Shared Neighborhood Hits	44
SwissProt Accessions	P20918, Q8CIS2, Q91WJ5	Gene names	Plg
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

PRR12_HUMAN
θ value	0.0961366 (rank : 690)	NC score	0.044545 (rank : 1043)
Query Neighborhood Hits	1113	Target Neighborhood Hits	460	Shared Neighborhood Hits	94
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

SF3A1_HUMAN
θ value	0.0961366 (rank : 691)	NC score	0.028018 (rank : 1119)
Query Neighborhood Hits	1113	Target Neighborhood Hits	199	Shared Neighborhood Hits	44
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

SPR2F_MOUSE
θ value	0.0961366 (rank : 692)	NC score	0.051146 (rank : 1016)
Query Neighborhood Hits	1113	Target Neighborhood Hits	43	Shared Neighborhood Hits	19
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

TLL1_MOUSE
θ value	0.0961366 (rank : 693)	NC score	0.250579 (rank : 552)
Query Neighborhood Hits	1113	Target Neighborhood Hits	237	Shared Neighborhood Hits	182
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

ADA32_HUMAN
θ value	0.125558 (rank : 694)	NC score	0.151554 (rank : 712)
Query Neighborhood Hits	1113	Target Neighborhood Hits	216	Shared Neighborhood Hits	175
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ANR43_HUMAN
θ value	0.125558 (rank : 695)	NC score	0.304689 (rank : 483)
Query Neighborhood Hits	1113	Target Neighborhood Hits	209	Shared Neighborhood Hits	199
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

ATS13_MOUSE
θ value	0.125558 (rank : 696)	NC score	0.044177 (rank : 1046)
Query Neighborhood Hits	1113	Target Neighborhood Hits	227	Shared Neighborhood Hits	104
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

EPGN_MOUSE
θ value	0.125558 (rank : 697)	NC score	0.144803 (rank : 726)
Query Neighborhood Hits	1113	Target Neighborhood Hits	63	Shared Neighborhood Hits	59
SwissProt Accessions	Q924X1, Q8CEX5	Gene names	Epgn
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

KR511_HUMAN
θ value	0.125558 (rank : 698)	NC score	0.454042 (rank : 202)
Query Neighborhood Hits	1113	Target Neighborhood Hits	231	Shared Neighborhood Hits	186
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

LCE1A_HUMAN
θ value	0.125558 (rank : 699)	NC score	0.241133 (rank : 568)
Query Neighborhood Hits	1113	Target Neighborhood Hits	47	Shared Neighborhood Hits	34
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

MASP2_HUMAN
θ value	0.125558 (rank : 700)	NC score	0.144859 (rank : 725)
Query Neighborhood Hits	1113	Target Neighborhood Hits	364	Shared Neighborhood Hits	165
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

SN1L2_HUMAN
θ value	0.125558 (rank : 701)	NC score	-0.002375 (rank : 1300)
Query Neighborhood Hits	1113	Target Neighborhood Hits	964	Shared Neighborhood Hits	73
SwissProt Accessions	Q9H0K1, O94878, Q6AZE2, Q76N03, Q8NCV7, Q96CZ8	Gene names	SNF1LK2, KIAA0781, QIK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Qin- induced kinase).

TLL1_HUMAN
θ value	0.125558 (rank : 702)	NC score	0.243539 (rank : 566)
Query Neighborhood Hits	1113	Target Neighborhood Hits	236	Shared Neighborhood Hits	178
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL2_MOUSE
θ value	0.125558 (rank : 703)	NC score	0.236951 (rank : 572)
Query Neighborhood Hits	1113	Target Neighborhood Hits	240	Shared Neighborhood Hits	182
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

UROK_HUMAN
θ value	0.125558 (rank : 704)	NC score	0.106013 (rank : 780)
Query Neighborhood Hits	1113	Target Neighborhood Hits	272	Shared Neighborhood Hits	126
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

UROL1_HUMAN
θ value	0.125558 (rank : 705)	NC score	0.267122 (rank : 523)
Query Neighborhood Hits	1113	Target Neighborhood Hits	213	Shared Neighborhood Hits	145
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

WASF4_HUMAN
θ value	0.125558 (rank : 706)	NC score	0.038258 (rank : 1069)
Query Neighborhood Hits	1113	Target Neighborhood Hits	282	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

ADA15_MOUSE
θ value	0.163984 (rank : 707)	NC score	0.199896 (rank : 623)
Query Neighborhood Hits	1113	Target Neighborhood Hits	324	Shared Neighborhood Hits	236
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADA28_HUMAN
θ value	0.163984 (rank : 708)	NC score	0.154372 (rank : 697)
Query Neighborhood Hits	1113	Target Neighborhood Hits	244	Shared Neighborhood Hits	183
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ATN1_HUMAN
θ value	0.163984 (rank : 709)	NC score	0.044958 (rank : 1040)
Query Neighborhood Hits	1113	Target Neighborhood Hits	676	Shared Neighborhood Hits	115
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

CLR59_HUMAN
θ value	0.163984 (rank : 710)	NC score	0.154352 (rank : 698)
Query Neighborhood Hits	1113	Target Neighborhood Hits	163	Shared Neighborhood Hits	139
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

CMTA2_HUMAN
θ value	0.163984 (rank : 711)	NC score	0.090619 (rank : 811)
Query Neighborhood Hits	1113	Target Neighborhood Hits	199	Shared Neighborhood Hits	107
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CN032_MOUSE
θ value	0.163984 (rank : 712)	NC score	0.037719 (rank : 1071)
Query Neighborhood Hits	1113	Target Neighborhood Hits	233	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CNTP1_HUMAN
θ value	0.163984 (rank : 713)	NC score	0.218567 (rank : 598)
Query Neighborhood Hits	1113	Target Neighborhood Hits	196	Shared Neighborhood Hits	135
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

CNTP1_MOUSE
θ value	0.163984 (rank : 714)	NC score	0.210877 (rank : 611)
Query Neighborhood Hits	1113	Target Neighborhood Hits	183	Shared Neighborhood Hits	127
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

EPGN_HUMAN
θ value	0.163984 (rank : 715)	NC score	0.129294 (rank : 756)
Query Neighborhood Hits	1113	Target Neighborhood Hits	59	Shared Neighborhood Hits	54
SwissProt Accessions	Q6UW88	Gene names	EPGN
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

EWS_HUMAN
θ value	0.163984 (rank : 716)	NC score	0.010644 (rank : 1229)
Query Neighborhood Hits	1113	Target Neighborhood Hits	249	Shared Neighborhood Hits	32
SwissProt Accessions	Q01844, Q92635	Gene names	EWSR1, EWS
Domain Architecture
Description	RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein).

MNT_HUMAN
θ value	0.163984 (rank : 717)	NC score	0.032384 (rank : 1091)
Query Neighborhood Hits	1113	Target Neighborhood Hits	496	Shared Neighborhood Hits	124
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

NET1_HUMAN
θ value	0.163984 (rank : 718)	NC score	0.295527 (rank : 492)
Query Neighborhood Hits	1113	Target Neighborhood Hits	149	Shared Neighborhood Hits	125
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

ADAM7_HUMAN
θ value	0.21417 (rank : 719)	NC score	0.165476 (rank : 686)
Query Neighborhood Hits	1113	Target Neighborhood Hits	221	Shared Neighborhood Hits	179
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

AN13A_HUMAN
θ value	0.21417 (rank : 720)	NC score	0.216980 (rank : 603)
Query Neighborhood Hits	1113	Target Neighborhood Hits	243	Shared Neighborhood Hits	212
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

APR3_MOUSE
θ value	0.21417 (rank : 721)	NC score	0.193087 (rank : 631)
Query Neighborhood Hits	1113	Target Neighborhood Hits	61	Shared Neighborhood Hits	59
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

BAI1_HUMAN
θ value	0.21417 (rank : 722)	NC score	0.093558 (rank : 806)
Query Neighborhood Hits	1113	Target Neighborhood Hits	375	Shared Neighborhood Hits	102
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAT2_HUMAN
θ value	0.21417 (rank : 723)	NC score	0.039880 (rank : 1064)
Query Neighborhood Hits	1113	Target Neighborhood Hits	931	Shared Neighborhood Hits	159
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CCNK_MOUSE
θ value	0.21417 (rank : 724)	NC score	0.020393 (rank : 1172)
Query Neighborhood Hits	1113	Target Neighborhood Hits	350	Shared Neighborhood Hits	64
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

DIDO1_HUMAN
θ value	0.21417 (rank : 725)	NC score	0.024499 (rank : 1140)
Query Neighborhood Hits	1113	Target Neighborhood Hits	960	Shared Neighborhood Hits	152
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

KR410_HUMAN
θ value	0.21417 (rank : 726)	NC score	0.259334 (rank : 536)
Query Neighborhood Hits	1113	Target Neighborhood Hits	156	Shared Neighborhood Hits	131
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

MEP1B_MOUSE
θ value	0.21417 (rank : 727)	NC score	0.143529 (rank : 731)
Query Neighborhood Hits	1113	Target Neighborhood Hits	127	Shared Neighborhood Hits	93
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

MINT_HUMAN
θ value	0.21417 (rank : 728)	NC score	0.022947 (rank : 1149)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1291	Shared Neighborhood Hits	157
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

OGFR_HUMAN
θ value	0.21417 (rank : 729)	NC score	0.046802 (rank : 1031)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1582	Shared Neighborhood Hits	262
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PCSK6_HUMAN
θ value	0.21417 (rank : 730)	NC score	0.186060 (rank : 644)
Query Neighborhood Hits	1113	Target Neighborhood Hits	298	Shared Neighborhood Hits	161
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

RELN_MOUSE
θ value	0.21417 (rank : 731)	NC score	0.237708 (rank : 571)
Query Neighborhood Hits	1113	Target Neighborhood Hits	235	Shared Neighborhood Hits	194
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

SEM5A_HUMAN
θ value	0.21417 (rank : 732)	NC score	0.043261 (rank : 1048)
Query Neighborhood Hits	1113	Target Neighborhood Hits	177	Shared Neighborhood Hits	59
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SMRC1_MOUSE
θ value	0.21417 (rank : 733)	NC score	0.022921 (rank : 1150)
Query Neighborhood Hits	1113	Target Neighborhood Hits	459	Shared Neighborhood Hits	57
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

SRPK1_HUMAN
θ value	0.21417 (rank : 734)	NC score	-0.003978 (rank : 1304)
Query Neighborhood Hits	1113	Target Neighborhood Hits	706	Shared Neighborhood Hits	41
SwissProt Accessions	Q96SB4, Q12890, Q5R364, Q5R365, Q8IY12	Gene names	SRPK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

TECTA_MOUSE
θ value	0.21417 (rank : 735)	NC score	0.215035 (rank : 607)
Query Neighborhood Hits	1113	Target Neighborhood Hits	244	Shared Neighborhood Hits	201
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TLX3_HUMAN
θ value	0.21417 (rank : 736)	NC score	-0.004410 (rank : 1305)
Query Neighborhood Hits	1113	Target Neighborhood Hits	403	Shared Neighborhood Hits	19
SwissProt Accessions	O43711, Q96AD3	Gene names	TLX3, HOX11L2
Domain Architecture
Description	T-cell leukemia homeobox protein 3 (Homeobox protein Hox-11L2).

BTC_MOUSE
θ value	0.279714 (rank : 737)	NC score	0.129835 (rank : 755)
Query Neighborhood Hits	1113	Target Neighborhood Hits	67	Shared Neighborhood Hits	62
SwissProt Accessions	Q05928	Gene names	Btc, Bcn
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

CIC_HUMAN
θ value	0.279714 (rank : 738)	NC score	0.032082 (rank : 1092)
Query Neighborhood Hits	1113	Target Neighborhood Hits	992	Shared Neighborhood Hits	205
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CMTA2_MOUSE
θ value	0.279714 (rank : 739)	NC score	0.081481 (rank : 841)
Query Neighborhood Hits	1113	Target Neighborhood Hits	216	Shared Neighborhood Hits	98
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

IGF1R_HUMAN
θ value	0.279714 (rank : 740)	NC score	0.027149 (rank : 1124)
Query Neighborhood Hits	1113	Target Neighborhood Hits	977	Shared Neighborhood Hits	160
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

INSR_MOUSE
θ value	0.279714 (rank : 741)	NC score	0.027455 (rank : 1121)
Query Neighborhood Hits	1113	Target Neighborhood Hits	968	Shared Neighborhood Hits	140
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

KR124_HUMAN
θ value	0.279714 (rank : 742)	NC score	0.146660 (rank : 721)
Query Neighborhood Hits	1113	Target Neighborhood Hits	124	Shared Neighborhood Hits	97
SwissProt Accessions	P60329	Gene names	KRTAP12-4, KAP12.4, KRTAP12.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-4 (Keratin-associated protein 12.4) (High sulfur keratin-associated protein 12.4).

KR171_HUMAN
θ value	0.279714 (rank : 743)	NC score	0.469459 (rank : 190)
Query Neighborhood Hits	1113	Target Neighborhood Hits	144	Shared Neighborhood Hits	125
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

LRP10_HUMAN
θ value	0.279714 (rank : 744)	NC score	0.139222 (rank : 737)
Query Neighborhood Hits	1113	Target Neighborhood Hits	197	Shared Neighborhood Hits	113
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

NUMB_HUMAN
θ value	0.279714 (rank : 745)	NC score	0.024513 (rank : 1139)
Query Neighborhood Hits	1113	Target Neighborhood Hits	112	Shared Neighborhood Hits	36
SwissProt Accessions	P49757, Q6NUQ7, Q86SY1, Q8WW73, Q9UBG1, Q9UEQ4, Q9UKE8, Q9UKE9, Q9UKF0, Q9UQJ4	Gene names	NUMB
Domain Architecture
Description	Protein numb homolog (h-Numb) (Protein S171).

SF3A2_HUMAN
θ value	0.279714 (rank : 746)	NC score	0.038666 (rank : 1068)
Query Neighborhood Hits	1113	Target Neighborhood Hits	263	Shared Neighborhood Hits	66
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SYN1_HUMAN
θ value	0.279714 (rank : 747)	NC score	0.030207 (rank : 1106)
Query Neighborhood Hits	1113	Target Neighborhood Hits	419	Shared Neighborhood Hits	89
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

T22D2_HUMAN
θ value	0.279714 (rank : 748)	NC score	0.024801 (rank : 1137)
Query Neighborhood Hits	1113	Target Neighborhood Hits	250	Shared Neighborhood Hits	57
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

WNK2_HUMAN
θ value	0.279714 (rank : 749)	NC score	0.004622 (rank : 1249)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1407	Shared Neighborhood Hits	162
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

YLPM1_MOUSE
θ value	0.279714 (rank : 750)	NC score	0.037126 (rank : 1073)
Query Neighborhood Hits	1113	Target Neighborhood Hits	505	Shared Neighborhood Hits	84
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ANKZ1_HUMAN
θ value	0.365318 (rank : 751)	NC score	0.172404 (rank : 661)
Query Neighborhood Hits	1113	Target Neighborhood Hits	236	Shared Neighborhood Hits	156
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

ASB9_MOUSE
θ value	0.365318 (rank : 752)	NC score	0.372982 (rank : 401)
Query Neighborhood Hits	1113	Target Neighborhood Hits	257	Shared Neighborhood Hits	248
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

CTGF_MOUSE
θ value	0.365318 (rank : 753)	NC score	0.082409 (rank : 836)
Query Neighborhood Hits	1113	Target Neighborhood Hits	124	Shared Neighborhood Hits	66
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

EPHB4_HUMAN
θ value	0.365318 (rank : 754)	NC score	0.050364 (rank : 1024)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1056	Shared Neighborhood Hits	183
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

ESM1_HUMAN
θ value	0.365318 (rank : 755)	NC score	0.196676 (rank : 625)
Query Neighborhood Hits	1113	Target Neighborhood Hits	110	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

EZH1_HUMAN
θ value	0.365318 (rank : 756)	NC score	0.042842 (rank : 1051)
Query Neighborhood Hits	1113	Target Neighborhood Hits	121	Shared Neighborhood Hits	56
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH2_HUMAN
θ value	0.365318 (rank : 757)	NC score	0.040558 (rank : 1061)
Query Neighborhood Hits	1113	Target Neighborhood Hits	84	Shared Neighborhood Hits	44
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH2_MOUSE
θ value	0.365318 (rank : 758)	NC score	0.041144 (rank : 1058)
Query Neighborhood Hits	1113	Target Neighborhood Hits	86	Shared Neighborhood Hits	46
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

FX4L4_HUMAN
θ value	0.365318 (rank : 759)	NC score	-0.002377 (rank : 1301)
Query Neighborhood Hits	1113	Target Neighborhood Hits	101	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WXT5	Gene names	FOXD4L4, FOXD4B
Domain Architecture
Description	Forkhead box protein D4-like 4 (Forkhead box protein D4B) (Myeloid factor-gamma).

HBEGF_HUMAN
θ value	0.365318 (rank : 760)	NC score	0.115217 (rank : 773)
Query Neighborhood Hits	1113	Target Neighborhood Hits	61	Shared Neighborhood Hits	56
SwissProt Accessions	Q99075	Gene names	HBEGF, DTR, HEGFL
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF) (Diphtheria toxin receptor) (DT-R).

MATN1_HUMAN
θ value	0.365318 (rank : 761)	NC score	0.204590 (rank : 616)
Query Neighborhood Hits	1113	Target Neighborhood Hits	191	Shared Neighborhood Hits	144
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MUC1_HUMAN
θ value	0.365318 (rank : 762)	NC score	0.054029 (rank : 988)
Query Neighborhood Hits	1113	Target Neighborhood Hits	975	Shared Neighborhood Hits	225
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

NCOA3_HUMAN
θ value	0.365318 (rank : 763)	NC score	0.010482 (rank : 1231)
Query Neighborhood Hits	1113	Target Neighborhood Hits	171	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

RC3H1_HUMAN
θ value	0.365318 (rank : 764)	NC score	0.018728 (rank : 1184)
Query Neighborhood Hits	1113	Target Neighborhood Hits	433	Shared Neighborhood Hits	97
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RELN_HUMAN
θ value	0.365318 (rank : 765)	NC score	0.228042 (rank : 581)
Query Neighborhood Hits	1113	Target Neighborhood Hits	233	Shared Neighborhood Hits	191
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

SF01_HUMAN
θ value	0.365318 (rank : 766)	NC score	0.023316 (rank : 1147)
Query Neighborhood Hits	1113	Target Neighborhood Hits	287	Shared Neighborhood Hits	68
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SPR2I_MOUSE
θ value	0.365318 (rank : 767)	NC score	0.063294 (rank : 921)
Query Neighborhood Hits	1113	Target Neighborhood Hits	45	Shared Neighborhood Hits	20
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

SRRM1_MOUSE
θ value	0.365318 (rank : 768)	NC score	0.044486 (rank : 1044)
Query Neighborhood Hits	1113	Target Neighborhood Hits	966	Shared Neighborhood Hits	175
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SYMPK_MOUSE
θ value	0.365318 (rank : 769)	NC score	0.010792 (rank : 1227)
Query Neighborhood Hits	1113	Target Neighborhood Hits	109	Shared Neighborhood Hits	15
SwissProt Accessions	Q80X82	Gene names	Sympk
Domain Architecture	No domain graphic available
Description	Symplekin.

AAK1_HUMAN
θ value	0.47712 (rank : 770)	NC score	0.003016 (rank : 1265)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1077	Shared Neighborhood Hits	128
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

ADM1B_MOUSE
θ value	0.47712 (rank : 771)	NC score	0.144114 (rank : 728)
Query Neighborhood Hits	1113	Target Neighborhood Hits	236	Shared Neighborhood Hits	159
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

AN13B_HUMAN
θ value	0.47712 (rank : 772)	NC score	0.244770 (rank : 564)
Query Neighborhood Hits	1113	Target Neighborhood Hits	265	Shared Neighborhood Hits	248
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13B_MOUSE
θ value	0.47712 (rank : 773)	NC score	0.246722 (rank : 561)
Query Neighborhood Hits	1113	Target Neighborhood Hits	276	Shared Neighborhood Hits	248
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

ANKZ1_MOUSE
θ value	0.47712 (rank : 774)	NC score	0.175899 (rank : 656)
Query Neighborhood Hits	1113	Target Neighborhood Hits	208	Shared Neighborhood Hits	150
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

BMPER_MOUSE
θ value	0.47712 (rank : 775)	NC score	0.203865 (rank : 617)
Query Neighborhood Hits	1113	Target Neighborhood Hits	194	Shared Neighborhood Hits	147
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

CENG2_MOUSE
θ value	0.47712 (rank : 776)	NC score	0.167925 (rank : 681)
Query Neighborhood Hits	1113	Target Neighborhood Hits	463	Shared Neighborhood Hits	249
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

CO8A_MOUSE
θ value	0.47712 (rank : 777)	NC score	0.140704 (rank : 735)
Query Neighborhood Hits	1113	Target Neighborhood Hits	182	Shared Neighborhood Hits	96
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO9_HUMAN
θ value	0.47712 (rank : 778)	NC score	0.152532 (rank : 708)
Query Neighborhood Hits	1113	Target Neighborhood Hits	147	Shared Neighborhood Hits	99
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

EPN3_HUMAN
θ value	0.47712 (rank : 779)	NC score	0.018222 (rank : 1188)
Query Neighborhood Hits	1113	Target Neighborhood Hits	197	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

FSTL3_MOUSE
θ value	0.47712 (rank : 780)	NC score	0.169789 (rank : 673)
Query Neighborhood Hits	1113	Target Neighborhood Hits	152	Shared Neighborhood Hits	101
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

GFRAL_MOUSE
θ value	0.47712 (rank : 781)	NC score	0.030255 (rank : 1105)
Query Neighborhood Hits	1113	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	Q6SJE0, Q6SJD9	Gene names	Gfral, Gral
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-like precursor.

HXA3_HUMAN
θ value	0.47712 (rank : 782)	NC score	-0.001001 (rank : 1296)
Query Neighborhood Hits	1113	Target Neighborhood Hits	535	Shared Neighborhood Hits	53
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

ITSN1_MOUSE
θ value	0.47712 (rank : 783)	NC score	0.006250 (rank : 1244)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1669	Shared Neighborhood Hits	127
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

NCOA6_HUMAN
θ value	0.47712 (rank : 784)	NC score	0.068273 (rank : 890)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1202	Shared Neighborhood Hits	238
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

PCLO_MOUSE
θ value	0.47712 (rank : 785)	NC score	0.031336 (rank : 1095)
Query Neighborhood Hits	1113	Target Neighborhood Hits	2275	Shared Neighborhood Hits	289
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RXRB_HUMAN
θ value	0.47712 (rank : 786)	NC score	0.000100 (rank : 1289)
Query Neighborhood Hits	1113	Target Neighborhood Hits	280	Shared Neighborhood Hits	52
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

SF01_MOUSE
θ value	0.47712 (rank : 787)	NC score	0.021519 (rank : 1168)
Query Neighborhood Hits	1113	Target Neighborhood Hits	240	Shared Neighborhood Hits	57
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SPR2E_MOUSE
θ value	0.47712 (rank : 788)	NC score	0.054526 (rank : 983)
Query Neighborhood Hits	1113	Target Neighborhood Hits	45	Shared Neighborhood Hits	20
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

TAB3_MOUSE
θ value	0.47712 (rank : 789)	NC score	0.022058 (rank : 1162)
Query Neighborhood Hits	1113	Target Neighborhood Hits	273	Shared Neighborhood Hits	72
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

TRPC6_HUMAN
θ value	0.47712 (rank : 790)	NC score	0.054214 (rank : 984)
Query Neighborhood Hits	1113	Target Neighborhood Hits	171	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

TRPV4_MOUSE
θ value	0.47712 (rank : 791)	NC score	0.068785 (rank : 885)
Query Neighborhood Hits	1113	Target Neighborhood Hits	117	Shared Neighborhood Hits	76
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

CD45_MOUSE
θ value	0.62314 (rank : 792)	NC score	0.002435 (rank : 1271)
Query Neighborhood Hits	1113	Target Neighborhood Hits	178	Shared Neighborhood Hits	28
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

CHCH2_HUMAN
θ value	0.62314 (rank : 793)	NC score	0.019955 (rank : 1174)
Query Neighborhood Hits	1113	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6H1, Q6NZ50	Gene names	CHCHD2
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 (HCV NS2 trans-regulated protein) (NS2TP).

CO8A_HUMAN
θ value	0.62314 (rank : 794)	NC score	0.143918 (rank : 729)
Query Neighborhood Hits	1113	Target Neighborhood Hits	200	Shared Neighborhood Hits	115
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

ERBB3_HUMAN
θ value	0.62314 (rank : 795)	NC score	0.022389 (rank : 1158)
Query Neighborhood Hits	1113	Target Neighborhood Hits	918	Shared Neighborhood Hits	137
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

EREG_HUMAN
θ value	0.62314 (rank : 796)	NC score	0.171585 (rank : 665)
Query Neighborhood Hits	1113	Target Neighborhood Hits	73	Shared Neighborhood Hits	67
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

EZH1_MOUSE
θ value	0.62314 (rank : 797)	NC score	0.043124 (rank : 1049)
Query Neighborhood Hits	1113	Target Neighborhood Hits	126	Shared Neighborhood Hits	64
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

FHR3_HUMAN
θ value	0.62314 (rank : 798)	NC score	0.027081 (rank : 1125)
Query Neighborhood Hits	1113	Target Neighborhood Hits	74	Shared Neighborhood Hits	33
SwissProt Accessions	Q02985, Q9UJ16	Gene names	CFHL3, FHR3
Domain Architecture
Description	Complement factor H-related protein 3 precursor (FHR-3) (H factor-like protein 3) (DOWN16).

KR413_HUMAN
θ value	0.62314 (rank : 799)	NC score	0.209661 (rank : 613)
Query Neighborhood Hits	1113	Target Neighborhood Hits	112	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

KRA56_HUMAN
θ value	0.62314 (rank : 800)	NC score	0.426643 (rank : 259)
Query Neighborhood Hits	1113	Target Neighborhood Hits	207	Shared Neighborhood Hits	173
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

MT1B_HUMAN
θ value	0.62314 (rank : 801)	NC score	0.098956 (rank : 796)
Query Neighborhood Hits	1113	Target Neighborhood Hits	87	Shared Neighborhood Hits	67
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

MUC13_HUMAN
θ value	0.62314 (rank : 802)	NC score	0.192107 (rank : 634)
Query Neighborhood Hits	1113	Target Neighborhood Hits	164	Shared Neighborhood Hits	106
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

NACAM_MOUSE
θ value	0.62314 (rank : 803)	NC score	0.063328 (rank : 920)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1866	Shared Neighborhood Hits	295
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PCD15_HUMAN
θ value	0.62314 (rank : 804)	NC score	0.036045 (rank : 1076)
Query Neighborhood Hits	1113	Target Neighborhood Hits	289	Shared Neighborhood Hits	38
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

SETB1_MOUSE
θ value	0.62314 (rank : 805)	NC score	0.039645 (rank : 1066)
Query Neighborhood Hits	1113	Target Neighborhood Hits	150	Shared Neighborhood Hits	46
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SFPQ_HUMAN
θ value	0.62314 (rank : 806)	NC score	0.013174 (rank : 1218)
Query Neighborhood Hits	1113	Target Neighborhood Hits	986	Shared Neighborhood Hits	110
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

TNR5_MOUSE
θ value	0.62314 (rank : 807)	NC score	0.077948 (rank : 852)
Query Neighborhood Hits	1113	Target Neighborhood Hits	131	Shared Neighborhood Hits	71
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TRI42_MOUSE
θ value	0.62314 (rank : 808)	NC score	0.040254 (rank : 1063)
Query Neighborhood Hits	1113	Target Neighborhood Hits	316	Shared Neighborhood Hits	85
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRPC6_MOUSE
θ value	0.62314 (rank : 809)	NC score	0.038692 (rank : 1067)
Query Neighborhood Hits	1113	Target Neighborhood Hits	171	Shared Neighborhood Hits	90
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPV4_HUMAN
θ value	0.62314 (rank : 810)	NC score	0.081452 (rank : 843)
Query Neighborhood Hits	1113	Target Neighborhood Hits	150	Shared Neighborhood Hits	87
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

WASF3_HUMAN
θ value	0.62314 (rank : 811)	NC score	0.040564 (rank : 1060)
Query Neighborhood Hits	1113	Target Neighborhood Hits	204	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

ADA10_HUMAN
θ value	0.813845 (rank : 812)	NC score	0.160556 (rank : 691)
Query Neighborhood Hits	1113	Target Neighborhood Hits	189	Shared Neighborhood Hits	149
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ANKY1_HUMAN
θ value	0.813845 (rank : 813)	NC score	0.254229 (rank : 548)
Query Neighborhood Hits	1113	Target Neighborhood Hits	248	Shared Neighborhood Hits	201
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

CENG2_HUMAN
θ value	0.813845 (rank : 814)	NC score	0.167055 (rank : 685)
Query Neighborhood Hits	1113	Target Neighborhood Hits	471	Shared Neighborhood Hits	250
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

CRK_MOUSE
θ value	0.813845 (rank : 815)	NC score	0.000794 (rank : 1282)
Query Neighborhood Hits	1113	Target Neighborhood Hits	314	Shared Neighborhood Hits	22
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

DGKZ_MOUSE
θ value	0.813845 (rank : 816)	NC score	0.168602 (rank : 678)
Query Neighborhood Hits	1113	Target Neighborhood Hits	542	Shared Neighborhood Hits	200
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

FSTL3_HUMAN
θ value	0.813845 (rank : 817)	NC score	0.179504 (rank : 652)
Query Neighborhood Hits	1113	Target Neighborhood Hits	162	Shared Neighborhood Hits	106
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

GP179_HUMAN
θ value	0.813845 (rank : 818)	NC score	0.066221 (rank : 903)
Query Neighborhood Hits	1113	Target Neighborhood Hits	372	Shared Neighborhood Hits	78
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

INSR_HUMAN
θ value	0.813845 (rank : 819)	NC score	0.031017 (rank : 1096)
Query Neighborhood Hits	1113	Target Neighborhood Hits	963	Shared Neighborhood Hits	143
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

ITSN1_HUMAN
θ value	0.813845 (rank : 820)	NC score	0.004387 (rank : 1252)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1757	Shared Neighborhood Hits	148
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

PAK6_HUMAN
θ value	0.813845 (rank : 821)	NC score	-0.004885 (rank : 1310)
Query Neighborhood Hits	1113	Target Neighborhood Hits	915	Shared Neighborhood Hits	68
SwissProt Accessions	Q9NQU5	Gene names	PAK6, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (p21-activated kinase 6) (PAK-6) (PAK-5).

PAPPA_MOUSE
θ value	0.813845 (rank : 822)	NC score	0.108973 (rank : 778)
Query Neighborhood Hits	1113	Target Neighborhood Hits	153	Shared Neighborhood Hits	84
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

SFPQ_MOUSE
θ value	0.813845 (rank : 823)	NC score	0.017495 (rank : 1192)
Query Neighborhood Hits	1113	Target Neighborhood Hits	958	Shared Neighborhood Hits	104
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SOX30_HUMAN
θ value	0.813845 (rank : 824)	NC score	0.016556 (rank : 1195)
Query Neighborhood Hits	1113	Target Neighborhood Hits	305	Shared Neighborhood Hits	84
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

SYN1_MOUSE
θ value	0.813845 (rank : 825)	NC score	0.022043 (rank : 1163)
Query Neighborhood Hits	1113	Target Neighborhood Hits	363	Shared Neighborhood Hits	81
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

TBX4_HUMAN
θ value	0.813845 (rank : 826)	NC score	0.004203 (rank : 1255)
Query Neighborhood Hits	1113	Target Neighborhood Hits	70	Shared Neighborhood Hits	15
SwissProt Accessions	P57082	Gene names	TBX4
Domain Architecture
Description	T-box transcription factor TBX4 (T-box protein 4).

TITIN_HUMAN
θ value	0.813845 (rank : 827)	NC score	0.023518 (rank : 1145)
Query Neighborhood Hits	1113	Target Neighborhood Hits	2923	Shared Neighborhood Hits	232
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TNR1B_MOUSE
θ value	0.813845 (rank : 828)	NC score	0.035978 (rank : 1077)
Query Neighborhood Hits	1113	Target Neighborhood Hits	123	Shared Neighborhood Hits	51
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TRAF6_MOUSE
θ value	0.813845 (rank : 829)	NC score	0.004238 (rank : 1254)
Query Neighborhood Hits	1113	Target Neighborhood Hits	255	Shared Neighborhood Hits	17
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

TRPV1_HUMAN
θ value	0.813845 (rank : 830)	NC score	0.125673 (rank : 761)
Query Neighborhood Hits	1113	Target Neighborhood Hits	184	Shared Neighborhood Hits	145
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

TYRP2_HUMAN
θ value	0.813845 (rank : 831)	NC score	0.034502 (rank : 1085)
Query Neighborhood Hits	1113	Target Neighborhood Hits	42	Shared Neighborhood Hits	36
SwissProt Accessions	P40126	Gene names	DCT, TYRP2
Domain Architecture
Description	L-dopachrome tautomerase precursor (EC 5.3.3.12) (DT) (DCT) (L- dopachrome delta-isomerase) (Tyrosinase-related protein 2) (TRP-2) (TRP2).

3BP1_MOUSE
θ value	1.06291 (rank : 832)	NC score	0.010732 (rank : 1228)
Query Neighborhood Hits	1113	Target Neighborhood Hits	238	Shared Neighborhood Hits	41
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

ANR43_MOUSE
θ value	1.06291 (rank : 833)	NC score	0.292621 (rank : 497)
Query Neighborhood Hits	1113	Target Neighborhood Hits	214	Shared Neighborhood Hits	201
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

ANX11_HUMAN
θ value	1.06291 (rank : 834)	NC score	0.001469 (rank : 1278)
Query Neighborhood Hits	1113	Target Neighborhood Hits	192	Shared Neighborhood Hits	36
SwissProt Accessions	P50995	Gene names	ANXA11, ANX11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50) (56 kDa autoantigen).

BMPER_HUMAN
θ value	1.06291 (rank : 835)	NC score	0.189352 (rank : 640)
Query Neighborhood Hits	1113	Target Neighborhood Hits	175	Shared Neighborhood Hits	133
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

CD2L7_HUMAN
θ value	1.06291 (rank : 836)	NC score	-0.002300 (rank : 1299)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1275	Shared Neighborhood Hits	121
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

CLC14_MOUSE
θ value	1.06291 (rank : 837)	NC score	0.259233 (rank : 537)
Query Neighborhood Hits	1113	Target Neighborhood Hits	120	Shared Neighborhood Hits	111
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

COL_HUMAN
θ value	1.06291 (rank : 838)	NC score	0.034546 (rank : 1084)
Query Neighborhood Hits	1113	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	P04118	Gene names	CLPS
Domain Architecture
Description	Colipase precursor.

CRK_HUMAN
θ value	1.06291 (rank : 839)	NC score	0.000476 (rank : 1286)
Query Neighborhood Hits	1113	Target Neighborhood Hits	308	Shared Neighborhood Hits	19
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

HCN2_HUMAN
θ value	1.06291 (rank : 840)	NC score	0.004343 (rank : 1253)
Query Neighborhood Hits	1113	Target Neighborhood Hits	369	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HDAC7_MOUSE
θ value	1.06291 (rank : 841)	NC score	0.003786 (rank : 1258)
Query Neighborhood Hits	1113	Target Neighborhood Hits	85	Shared Neighborhood Hits	20
SwissProt Accessions	Q8C2B3, Q8C2C9, Q8C8X4, Q8CB80, Q8CDA3, Q9JL72	Gene names	Hdac7a, Hdac7
Domain Architecture
Description	Histone deacetylase 7a (HD7a).

IGF1R_MOUSE
θ value	1.06291 (rank : 842)	NC score	0.030946 (rank : 1097)
Query Neighborhood Hits	1113	Target Neighborhood Hits	973	Shared Neighborhood Hits	160
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

KR510_HUMAN
θ value	1.06291 (rank : 843)	NC score	0.391733 (rank : 361)
Query Neighborhood Hits	1113	Target Neighborhood Hits	217	Shared Neighborhood Hits	169
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

LCE1D_HUMAN
θ value	1.06291 (rank : 844)	NC score	0.276399 (rank : 512)
Query Neighborhood Hits	1113	Target Neighborhood Hits	44	Shared Neighborhood Hits	32
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LDB3_HUMAN
θ value	1.06291 (rank : 845)	NC score	0.000612 (rank : 1283)
Query Neighborhood Hits	1113	Target Neighborhood Hits	497	Shared Neighborhood Hits	58
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

LRP3_HUMAN
θ value	1.06291 (rank : 846)	NC score	0.175503 (rank : 657)
Query Neighborhood Hits	1113	Target Neighborhood Hits	280	Shared Neighborhood Hits	163
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

MAML1_MOUSE
θ value	1.06291 (rank : 847)	NC score	0.019101 (rank : 1180)
Query Neighborhood Hits	1113	Target Neighborhood Hits	279	Shared Neighborhood Hits	65
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

NCA11_MOUSE
θ value	1.06291 (rank : 848)	NC score	0.018337 (rank : 1186)
Query Neighborhood Hits	1113	Target Neighborhood Hits	661	Shared Neighborhood Hits	78
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

NCOR2_MOUSE
θ value	1.06291 (rank : 849)	NC score	0.015177 (rank : 1202)
Query Neighborhood Hits	1113	Target Neighborhood Hits	790	Shared Neighborhood Hits	117
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

PDC6I_HUMAN
θ value	1.06291 (rank : 850)	NC score	0.034060 (rank : 1088)
Query Neighborhood Hits	1113	Target Neighborhood Hits	278	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

PRDM2_HUMAN
θ value	1.06291 (rank : 851)	NC score	-0.012497 (rank : 1319)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1135	Shared Neighborhood Hits	97
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

PRP1_HUMAN
θ value	1.06291 (rank : 852)	NC score	0.033708 (rank : 1090)
Query Neighborhood Hits	1113	Target Neighborhood Hits	385	Shared Neighborhood Hits	71
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

RAGE_MOUSE
θ value	1.06291 (rank : 853)	NC score	0.011678 (rank : 1222)
Query Neighborhood Hits	1113	Target Neighborhood Hits	295	Shared Neighborhood Hits	15
SwissProt Accessions	Q62151	Gene names	Ager, Rage
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

SEM5B_HUMAN
θ value	1.06291 (rank : 854)	NC score	0.033905 (rank : 1089)
Query Neighborhood Hits	1113	Target Neighborhood Hits	178	Shared Neighborhood Hits	59
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

SF3A2_MOUSE
θ value	1.06291 (rank : 855)	NC score	0.042280 (rank : 1054)
Query Neighborhood Hits	1113	Target Neighborhood Hits	247	Shared Neighborhood Hits	70
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SRRM1_HUMAN
θ value	1.06291 (rank : 856)	NC score	0.028203 (rank : 1118)
Query Neighborhood Hits	1113	Target Neighborhood Hits	690	Shared Neighborhood Hits	97
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

ZBT45_HUMAN
θ value	1.06291 (rank : 857)	NC score	-0.019199 (rank : 1326)
Query Neighborhood Hits	1113	Target Neighborhood Hits	901	Shared Neighborhood Hits	47
SwissProt Accessions	Q96K62	Gene names	ZBTB45, ZNF499
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 45 (Zinc finger protein 499).

AN13A_MOUSE
θ value	1.38821 (rank : 858)	NC score	0.202564 (rank : 619)
Query Neighborhood Hits	1113	Target Neighborhood Hits	226	Shared Neighborhood Hits	211
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

APR3_HUMAN
θ value	1.38821 (rank : 859)	NC score	0.174465 (rank : 659)
Query Neighborhood Hits	1113	Target Neighborhood Hits	50	Shared Neighborhood Hits	49
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

BRD4_HUMAN
θ value	1.38821 (rank : 860)	NC score	0.022282 (rank : 1160)
Query Neighborhood Hits	1113	Target Neighborhood Hits	851	Shared Neighborhood Hits	110
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CD2_MOUSE
θ value	1.38821 (rank : 861)	NC score	0.014465 (rank : 1210)
Query Neighborhood Hits	1113	Target Neighborhood Hits	45	Shared Neighborhood Hits	16
SwissProt Accessions	P08920, Q61394	Gene names	Cd2, Ly-37
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Lymphocyte antigen Ly-37).

CPSF6_HUMAN
θ value	1.38821 (rank : 862)	NC score	0.027374 (rank : 1122)
Query Neighborhood Hits	1113	Target Neighborhood Hits	359	Shared Neighborhood Hits	62
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	1.38821 (rank : 863)	NC score	0.027455 (rank : 1120)
Query Neighborhood Hits	1113	Target Neighborhood Hits	356	Shared Neighborhood Hits	62
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CRTC1_HUMAN
θ value	1.38821 (rank : 864)	NC score	0.022576 (rank : 1155)
Query Neighborhood Hits	1113	Target Neighborhood Hits	319	Shared Neighborhood Hits	87
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

CYR61_HUMAN
θ value	1.38821 (rank : 865)	NC score	0.089786 (rank : 814)
Query Neighborhood Hits	1113	Target Neighborhood Hits	159	Shared Neighborhood Hits	84
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

CYR61_MOUSE
θ value	1.38821 (rank : 866)	NC score	0.092730 (rank : 807)
Query Neighborhood Hits	1113	Target Neighborhood Hits	156	Shared Neighborhood Hits	80
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

ESX1L_HUMAN
θ value	1.38821 (rank : 867)	NC score	-0.004740 (rank : 1309)
Query Neighborhood Hits	1113	Target Neighborhood Hits	498	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N693, Q7Z6K7	Gene names	ESX1L, ESX1R
Domain Architecture
Description	Extraembryonic, spermatogenesis, homeobox 1-like protein.

HRX_HUMAN
θ value	1.38821 (rank : 868)	NC score	0.023159 (rank : 1148)
Query Neighborhood Hits	1113	Target Neighborhood Hits	825	Shared Neighborhood Hits	110
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

K1802_MOUSE
θ value	1.38821 (rank : 869)	NC score	0.026406 (rank : 1131)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1596	Shared Neighborhood Hits	238
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LCE3C_HUMAN
θ value	1.38821 (rank : 870)	NC score	0.076492 (rank : 855)
Query Neighborhood Hits	1113	Target Neighborhood Hits	15	Shared Neighborhood Hits	11
SwissProt Accessions	Q5T5A8	Gene names	LCE3C, LEP15, SPRL3A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A).

MASP1_HUMAN
θ value	1.38821 (rank : 871)	NC score	0.134880 (rank : 748)
Query Neighborhood Hits	1113	Target Neighborhood Hits	369	Shared Neighborhood Hits	166
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

MASP1_MOUSE
θ value	1.38821 (rank : 872)	NC score	0.132379 (rank : 752)
Query Neighborhood Hits	1113	Target Neighborhood Hits	364	Shared Neighborhood Hits	167
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

OSTF1_MOUSE
θ value	1.38821 (rank : 873)	NC score	0.295745 (rank : 491)
Query Neighborhood Hits	1113	Target Neighborhood Hits	467	Shared Neighborhood Hits	251
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

PCLO_HUMAN
θ value	1.38821 (rank : 874)	NC score	0.034781 (rank : 1082)
Query Neighborhood Hits	1113	Target Neighborhood Hits	2046	Shared Neighborhood Hits	262
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PER1_MOUSE
θ value	1.38821 (rank : 875)	NC score	0.022632 (rank : 1153)
Query Neighborhood Hits	1113	Target Neighborhood Hits	235	Shared Neighborhood Hits	59
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

RC3H1_MOUSE
θ value	1.38821 (rank : 876)	NC score	0.006715 (rank : 1240)
Query Neighborhood Hits	1113	Target Neighborhood Hits	244	Shared Neighborhood Hits	17
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

SALL3_HUMAN
θ value	1.38821 (rank : 877)	NC score	-0.014679 (rank : 1322)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1066	Shared Neighborhood Hits	80
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

SMRC1_HUMAN
θ value	1.38821 (rank : 878)	NC score	0.025049 (rank : 1136)
Query Neighborhood Hits	1113	Target Neighborhood Hits	375	Shared Neighborhood Hits	57
SwissProt Accessions	Q92922, Q6P172, Q8IWH2	Gene names	SMARCC1, BAF155
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155).

SRRM2_HUMAN
θ value	1.38821 (rank : 879)	NC score	0.026474 (rank : 1130)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1296	Shared Neighborhood Hits	160
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TAF1C_HUMAN
θ value	1.38821 (rank : 880)	NC score	0.010517 (rank : 1230)
Query Neighborhood Hits	1113	Target Neighborhood Hits	36	Shared Neighborhood Hits	11
SwissProt Accessions	Q15572, Q59F67, Q8N6V3	Gene names	TAF1C
Domain Architecture	No domain graphic available
Description	TATA box-binding protein-associated factor RNA polymerase I subunit C (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (TBP-associated factor RNA polymerase I 110 kDa) (TAFI110).

TAF4_HUMAN
θ value	1.38821 (rank : 881)	NC score	0.035770 (rank : 1078)
Query Neighborhood Hits	1113	Target Neighborhood Hits	687	Shared Neighborhood Hits	105
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TRPV2_HUMAN
θ value	1.38821 (rank : 882)	NC score	0.118781 (rank : 771)
Query Neighborhood Hits	1113	Target Neighborhood Hits	130	Shared Neighborhood Hits	112
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

WASF1_MOUSE
θ value	1.38821 (rank : 883)	NC score	0.052991 (rank : 997)
Query Neighborhood Hits	1113	Target Neighborhood Hits	261	Shared Neighborhood Hits	72
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

WASIP_MOUSE
θ value	1.38821 (rank : 884)	NC score	0.040619 (rank : 1059)
Query Neighborhood Hits	1113	Target Neighborhood Hits	392	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

ALEX_HUMAN
θ value	1.81305 (rank : 885)	NC score	0.030273 (rank : 1104)
Query Neighborhood Hits	1113	Target Neighborhood Hits	361	Shared Neighborhood Hits	92
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

BAI1_MOUSE
θ value	1.81305 (rank : 886)	NC score	0.086744 (rank : 822)
Query Neighborhood Hits	1113	Target Neighborhood Hits	340	Shared Neighborhood Hits	96
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

EPHB6_HUMAN
θ value	1.81305 (rank : 887)	NC score	0.027360 (rank : 1123)
Query Neighborhood Hits	1113	Target Neighborhood Hits	912	Shared Neighborhood Hits	137
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

F13B_MOUSE
θ value	1.81305 (rank : 888)	NC score	0.041229 (rank : 1057)
Query Neighborhood Hits	1113	Target Neighborhood Hits	93	Shared Neighborhood Hits	44
SwissProt Accessions	Q07968	Gene names	F13b, Cf13b
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain).

GP1BA_HUMAN
θ value	1.81305 (rank : 889)	NC score	0.029669 (rank : 1110)
Query Neighborhood Hits	1113	Target Neighborhood Hits	407	Shared Neighborhood Hits	49
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

HBEGF_MOUSE
θ value	1.81305 (rank : 890)	NC score	0.085697 (rank : 825)
Query Neighborhood Hits	1113	Target Neighborhood Hits	48	Shared Neighborhood Hits	46
SwissProt Accessions	Q06186	Gene names	Hbegf, Dtr, Hegfl
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF).

IKBL_HUMAN
θ value	1.81305 (rank : 891)	NC score	0.170831 (rank : 668)
Query Neighborhood Hits	1113	Target Neighborhood Hits	168	Shared Neighborhood Hits	139
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

IKBL_MOUSE
θ value	1.81305 (rank : 892)	NC score	0.167771 (rank : 682)
Query Neighborhood Hits	1113	Target Neighborhood Hits	196	Shared Neighborhood Hits	140
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

LRP5_MOUSE
θ value	1.81305 (rank : 893)	NC score	0.243961 (rank : 565)
Query Neighborhood Hits	1113	Target Neighborhood Hits	236	Shared Neighborhood Hits	172
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

MAST4_HUMAN
θ value	1.81305 (rank : 894)	NC score	0.002082 (rank : 1275)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1804	Shared Neighborhood Hits	199
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MFRP_HUMAN
θ value	1.81305 (rank : 895)	NC score	0.080548 (rank : 848)
Query Neighborhood Hits	1113	Target Neighborhood Hits	165	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MK07_MOUSE
θ value	1.81305 (rank : 896)	NC score	-0.004653 (rank : 1308)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1054	Shared Neighborhood Hits	96
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

MLL3_MOUSE
θ value	1.81305 (rank : 897)	NC score	0.062902 (rank : 925)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1399	Shared Neighborhood Hits	282
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MSX1_HUMAN
θ value	1.81305 (rank : 898)	NC score	-0.008324 (rank : 1314)
Query Neighborhood Hits	1113	Target Neighborhood Hits	374	Shared Neighborhood Hits	18
SwissProt Accessions	P28360, Q96NY4	Gene names	MSX1, HOX7
Domain Architecture
Description	Homeobox protein MSX-1 (Msh homeobox 1-like protein) (Hox-7).

N4BP2_HUMAN
θ value	1.81305 (rank : 899)	NC score	0.014587 (rank : 1209)
Query Neighborhood Hits	1113	Target Neighborhood Hits	107	Shared Neighborhood Hits	13
SwissProt Accessions	Q86UW6, Q9NVK2, Q9P2D4	Gene names	N4BP2, B3BP, KIAA1413
Domain Architecture
Description	NEDD4-binding protein 2 (EC 3.-.-.-) (N4BP2) (BCL-3-binding protein).

NCOA2_HUMAN
θ value	1.81305 (rank : 900)	NC score	0.009323 (rank : 1235)
Query Neighborhood Hits	1113	Target Neighborhood Hits	281	Shared Neighborhood Hits	49
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

NRG3_HUMAN
θ value	1.81305 (rank : 901)	NC score	0.098122 (rank : 798)
Query Neighborhood Hits	1113	Target Neighborhood Hits	119	Shared Neighborhood Hits	78
SwissProt Accessions	P56975	Gene names	NRG3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

NRG3_MOUSE
θ value	1.81305 (rank : 902)	NC score	0.101504 (rank : 791)
Query Neighborhood Hits	1113	Target Neighborhood Hits	132	Shared Neighborhood Hits	85
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

PRG4_HUMAN
θ value	1.81305 (rank : 903)	NC score	0.031599 (rank : 1094)
Query Neighborhood Hits	1113	Target Neighborhood Hits	764	Shared Neighborhood Hits	123
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RFX1_HUMAN
θ value	1.81305 (rank : 904)	NC score	0.013972 (rank : 1213)
Query Neighborhood Hits	1113	Target Neighborhood Hits	256	Shared Neighborhood Hits	59
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

TNR25_HUMAN
θ value	1.81305 (rank : 905)	NC score	0.152678 (rank : 706)
Query Neighborhood Hits	1113	Target Neighborhood Hits	172	Shared Neighborhood Hits	90
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TTBK2_HUMAN
θ value	1.81305 (rank : 906)	NC score	-0.009229 (rank : 1315)
Query Neighborhood Hits	1113	Target Neighborhood Hits	822	Shared Neighborhood Hits	52
SwissProt Accessions	Q6IQ55, O94932, Q6ZN52, Q8IVV1	Gene names	TTBK2, KIAA0847
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2 (EC 2.7.11.1).

WASL_MOUSE
θ value	1.81305 (rank : 907)	NC score	0.022298 (rank : 1159)
Query Neighborhood Hits	1113	Target Neighborhood Hits	339	Shared Neighborhood Hits	72
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WNK4_HUMAN
θ value	1.81305 (rank : 908)	NC score	0.000515 (rank : 1285)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1043	Shared Neighborhood Hits	91
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

ZBTB3_HUMAN
θ value	1.81305 (rank : 909)	NC score	-0.016566 (rank : 1323)
Query Neighborhood Hits	1113	Target Neighborhood Hits	910	Shared Neighborhood Hits	59
SwissProt Accessions	Q9H5J0	Gene names	ZBTB3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

ADAM7_MOUSE
θ value	2.36792 (rank : 910)	NC score	0.138828 (rank : 739)
Query Neighborhood Hits	1113	Target Neighborhood Hits	200	Shared Neighborhood Hits	160
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

AMOT_HUMAN
θ value	2.36792 (rank : 911)	NC score	0.014654 (rank : 1207)
Query Neighborhood Hits	1113	Target Neighborhood Hits	712	Shared Neighborhood Hits	84
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

ANTR1_MOUSE
θ value	2.36792 (rank : 912)	NC score	0.016637 (rank : 1194)
Query Neighborhood Hits	1113	Target Neighborhood Hits	143	Shared Neighborhood Hits	43
SwissProt Accessions	Q9CZ52	Gene names	Antxr1, Atr, Tem8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

ASTL_HUMAN
θ value	2.36792 (rank : 913)	NC score	0.045466 (rank : 1037)
Query Neighborhood Hits	1113	Target Neighborhood Hits	252	Shared Neighborhood Hits	77
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

AUTS2_HUMAN
θ value	2.36792 (rank : 914)	NC score	0.014913 (rank : 1204)
Query Neighborhood Hits	1113	Target Neighborhood Hits	342	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

BSN_MOUSE
θ value	2.36792 (rank : 915)	NC score	0.045856 (rank : 1036)
Query Neighborhood Hits	1113	Target Neighborhood Hits	2057	Shared Neighborhood Hits	295
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

F19A1_HUMAN
θ value	2.36792 (rank : 916)	NC score	0.019473 (rank : 1177)
Query Neighborhood Hits	1113	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z5A9, Q8TCL8	Gene names	FAM19A1, TAFA1
Domain Architecture	No domain graphic available
Description	Protein FAM19A1 precursor (Chemokine-like protein TAFA-1).

F19A1_MOUSE
θ value	2.36792 (rank : 917)	NC score	0.019494 (rank : 1176)
Query Neighborhood Hits	1113	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TPG8	Gene names	Fam19a1, Tafa1
Domain Architecture	No domain graphic available
Description	Protein FAM19A1 precursor (Chemokine-like protein TAFA-1).

FILA_HUMAN
θ value	2.36792 (rank : 918)	NC score	0.004899 (rank : 1248)
Query Neighborhood Hits	1113	Target Neighborhood Hits	685	Shared Neighborhood Hits	54
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

FST_HUMAN
θ value	2.36792 (rank : 919)	NC score	0.137822 (rank : 741)
Query Neighborhood Hits	1113	Target Neighborhood Hits	129	Shared Neighborhood Hits	73
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

GLIS1_HUMAN
θ value	2.36792 (rank : 920)	NC score	-0.018924 (rank : 1324)
Query Neighborhood Hits	1113	Target Neighborhood Hits	748	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NBF1, Q8N9V9	Gene names	GLIS1
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS1 (GLI-similar 1).

MATN1_MOUSE
θ value	2.36792 (rank : 921)	NC score	0.202522 (rank : 620)
Query Neighborhood Hits	1113	Target Neighborhood Hits	186	Shared Neighborhood Hits	140
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MKS3_MOUSE
θ value	2.36792 (rank : 922)	NC score	0.137593 (rank : 743)
Query Neighborhood Hits	1113	Target Neighborhood Hits	89	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

MN1_HUMAN
θ value	2.36792 (rank : 923)	NC score	0.025082 (rank : 1135)
Query Neighborhood Hits	1113	Target Neighborhood Hits	196	Shared Neighborhood Hits	41
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

MT1L_HUMAN
θ value	2.36792 (rank : 924)	NC score	0.064744 (rank : 910)
Query Neighborhood Hits	1113	Target Neighborhood Hits	73	Shared Neighborhood Hits	52
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

OBSCN_HUMAN
θ value	2.36792 (rank : 925)	NC score	0.004533 (rank : 1250)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1931	Shared Neighborhood Hits	186
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

PI5PA_MOUSE
θ value	2.36792 (rank : 926)	NC score	0.024589 (rank : 1138)
Query Neighborhood Hits	1113	Target Neighborhood Hits	331	Shared Neighborhood Hits	86
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PTN23_MOUSE
θ value	2.36792 (rank : 927)	NC score	0.015695 (rank : 1199)
Query Neighborhood Hits	1113	Target Neighborhood Hits	726	Shared Neighborhood Hits	124
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

SAPS1_HUMAN
θ value	2.36792 (rank : 928)	NC score	0.029276 (rank : 1113)
Query Neighborhood Hits	1113	Target Neighborhood Hits	704	Shared Neighborhood Hits	168
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SC24C_HUMAN
θ value	2.36792 (rank : 929)	NC score	0.036772 (rank : 1075)
Query Neighborhood Hits	1113	Target Neighborhood Hits	662	Shared Neighborhood Hits	163
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SMRC2_MOUSE
θ value	2.36792 (rank : 930)	NC score	0.012017 (rank : 1220)
Query Neighborhood Hits	1113	Target Neighborhood Hits	487	Shared Neighborhood Hits	64
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SNCAP_HUMAN
θ value	2.36792 (rank : 931)	NC score	0.314357 (rank : 476)
Query Neighborhood Hits	1113	Target Neighborhood Hits	313	Shared Neighborhood Hits	235
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

SPR2B_MOUSE
θ value	2.36792 (rank : 932)	NC score	0.080179 (rank : 849)
Query Neighborhood Hits	1113	Target Neighborhood Hits	51	Shared Neighborhood Hits	28
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

SRBP1_HUMAN
θ value	2.36792 (rank : 933)	NC score	0.009407 (rank : 1234)
Query Neighborhood Hits	1113	Target Neighborhood Hits	225	Shared Neighborhood Hits	44
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

TECTA_HUMAN
θ value	2.36792 (rank : 934)	NC score	0.192563 (rank : 632)
Query Neighborhood Hits	1113	Target Neighborhood Hits	239	Shared Neighborhood Hits	192
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

TGFA_MOUSE
θ value	2.36792 (rank : 935)	NC score	0.089339 (rank : 815)
Query Neighborhood Hits	1113	Target Neighborhood Hits	62	Shared Neighborhood Hits	56
SwissProt Accessions	P48030	Gene names	Tgfa
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

TM16H_HUMAN
θ value	2.36792 (rank : 936)	NC score	0.005912 (rank : 1246)
Query Neighborhood Hits	1113	Target Neighborhood Hits	139	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HCE9	Gene names	TMEM16H, KIAA1623
Domain Architecture	No domain graphic available
Description	Transmembrane protein 16H.

TNR6_HUMAN
θ value	2.36792 (rank : 937)	NC score	0.053026 (rank : 996)
Query Neighborhood Hits	1113	Target Neighborhood Hits	95	Shared Neighborhood Hits	48
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TTC15_MOUSE
θ value	2.36792 (rank : 938)	NC score	0.008432 (rank : 1238)
Query Neighborhood Hits	1113	Target Neighborhood Hits	113	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K2L8, Q8BX27	Gene names	Ttc15
Domain Architecture
Description	Tetratricopeptide repeat protein 15 (TPR repeat protein 15).

VEGFC_MOUSE
θ value	2.36792 (rank : 939)	NC score	0.125222 (rank : 762)
Query Neighborhood Hits	1113	Target Neighborhood Hits	119	Shared Neighborhood Hits	94
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

YAP1_MOUSE
θ value	2.36792 (rank : 940)	NC score	0.002985 (rank : 1266)
Query Neighborhood Hits	1113	Target Neighborhood Hits	96	Shared Neighborhood Hits	13
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

ZNFX1_HUMAN
θ value	2.36792 (rank : 941)	NC score	0.108387 (rank : 779)
Query Neighborhood Hits	1113	Target Neighborhood Hits	308	Shared Neighborhood Hits	145
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ZSCA2_MOUSE
θ value	2.36792 (rank : 942)	NC score	-0.019840 (rank : 1327)
Query Neighborhood Hits	1113	Target Neighborhood Hits	767	Shared Neighborhood Hits	24
SwissProt Accessions	Q07230	Gene names	Zscan2, Zfp-29, Zfp29
Domain Architecture
Description	Zinc finger and SCAN domain-containing protein 2 (Zinc finger protein 29) (Zfp-29).

ANTR1_HUMAN
θ value	3.0926 (rank : 943)	NC score	0.018246 (rank : 1187)
Query Neighborhood Hits	1113	Target Neighborhood Hits	128	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H6X2, Q96P02, Q9NVP3	Gene names	ANTXR1, ATR, TEM8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

BRSK2_HUMAN
θ value	3.0926 (rank : 944)	NC score	-0.005097 (rank : 1311)
Query Neighborhood Hits	1113	Target Neighborhood Hits	897	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IWQ3, O60843, O95099, Q5J5B4, Q8TB60	Gene names	BRSK2, C11orf7, PEN11B, STK29
Domain Architecture
Description	BR serine/threonine-protein kinase 2 (EC 2.7.11.1) (Serine/threonine- protein kinase 29) (SAD1B).

BTC_HUMAN
θ value	3.0926 (rank : 945)	NC score	0.113520 (rank : 775)
Query Neighborhood Hits	1113	Target Neighborhood Hits	70	Shared Neighborhood Hits	63
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

CSMD1_HUMAN
θ value	3.0926 (rank : 946)	NC score	0.071131 (rank : 875)
Query Neighborhood Hits	1113	Target Neighborhood Hits	176	Shared Neighborhood Hits	75
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CT012_HUMAN
θ value	3.0926 (rank : 947)	NC score	0.195020 (rank : 628)
Query Neighborhood Hits	1113	Target Neighborhood Hits	205	Shared Neighborhood Hits	179
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

EP400_HUMAN
θ value	3.0926 (rank : 948)	NC score	0.012537 (rank : 1219)
Query Neighborhood Hits	1113	Target Neighborhood Hits	556	Shared Neighborhood Hits	92
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

EREG_MOUSE
θ value	3.0926 (rank : 949)	NC score	0.114036 (rank : 774)
Query Neighborhood Hits	1113	Target Neighborhood Hits	65	Shared Neighborhood Hits	56
SwissProt Accessions	Q61521, Q7M0A8	Gene names	Ereg
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

EWS_MOUSE
θ value	3.0926 (rank : 950)	NC score	0.003957 (rank : 1257)
Query Neighborhood Hits	1113	Target Neighborhood Hits	271	Shared Neighborhood Hits	30
SwissProt Accessions	Q61545	Gene names	Ewsr1, Ews, Ewsh
Domain Architecture
Description	RNA-binding protein EWS.

FINC_MOUSE
θ value	3.0926 (rank : 951)	NC score	0.096026 (rank : 800)
Query Neighborhood Hits	1113	Target Neighborhood Hits	309	Shared Neighborhood Hits	82
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

GIT2_HUMAN
θ value	3.0926 (rank : 952)	NC score	0.229715 (rank : 580)
Query Neighborhood Hits	1113	Target Neighborhood Hits	381	Shared Neighborhood Hits	242
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

GMIP_HUMAN
θ value	3.0926 (rank : 953)	NC score	-0.000602 (rank : 1294)
Query Neighborhood Hits	1113	Target Neighborhood Hits	225	Shared Neighborhood Hits	20
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

IF35_MOUSE
θ value	3.0926 (rank : 954)	NC score	0.014683 (rank : 1206)
Query Neighborhood Hits	1113	Target Neighborhood Hits	210	Shared Neighborhood Hits	45
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

IMPG1_MOUSE
θ value	3.0926 (rank : 955)	NC score	0.019946 (rank : 1175)
Query Neighborhood Hits	1113	Target Neighborhood Hits	50	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R1W8, Q9CTP8, Q9ES62, Q9ET31	Gene names	Impg1, Spacr
Domain Architecture	No domain graphic available
Description	Interphotoreceptor matrix proteoglycan 1 precursor (IPM 150 proteoglycan) (Sialoprotein associated with cones and rods).

KLF4_HUMAN
θ value	3.0926 (rank : 956)	NC score	-0.019143 (rank : 1325)
Query Neighborhood Hits	1113	Target Neighborhood Hits	709	Shared Neighborhood Hits	25
SwissProt Accessions	O43474, P78338, Q9UNP3	Gene names	KLF4, EZF, GKLF
Domain Architecture
Description	Krueppel-like factor 4 (Epithelial zinc-finger protein EZF) (Gut- enriched krueppel-like factor).

LRP5_HUMAN
θ value	3.0926 (rank : 957)	NC score	0.235947 (rank : 574)
Query Neighborhood Hits	1113	Target Neighborhood Hits	224	Shared Neighborhood Hits	168
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LYL1_HUMAN
θ value	3.0926 (rank : 958)	NC score	0.002509 (rank : 1269)
Query Neighborhood Hits	1113	Target Neighborhood Hits	113	Shared Neighborhood Hits	11
SwissProt Accessions	P12980, O76102	Gene names	LYL1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

MKS3_HUMAN
θ value	3.0926 (rank : 959)	NC score	0.137322 (rank : 744)
Query Neighborhood Hits	1113	Target Neighborhood Hits	79	Shared Neighborhood Hits	68
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

MNT_MOUSE
θ value	3.0926 (rank : 960)	NC score	0.022737 (rank : 1152)
Query Neighborhood Hits	1113	Target Neighborhood Hits	432	Shared Neighborhood Hits	93
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MT4_HUMAN
θ value	3.0926 (rank : 961)	NC score	0.132107 (rank : 753)
Query Neighborhood Hits	1113	Target Neighborhood Hits	83	Shared Neighborhood Hits	61
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MUC7_HUMAN
θ value	3.0926 (rank : 962)	NC score	0.034439 (rank : 1086)
Query Neighborhood Hits	1113	Target Neighborhood Hits	538	Shared Neighborhood Hits	99
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

OC90_MOUSE
θ value	3.0926 (rank : 963)	NC score	0.035086 (rank : 1081)
Query Neighborhood Hits	1113	Target Neighborhood Hits	48	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z0L3, Q9CZ60, Q9Z225	Gene names	Oc90, Onc-95, Pla2ll
Domain Architecture
Description	Otoconin 90 precursor (Oc90) (Otoconin-95) (Oc95).

PRR13_HUMAN
θ value	3.0926 (rank : 964)	NC score	0.026479 (rank : 1129)
Query Neighborhood Hits	1113	Target Neighborhood Hits	105	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

RERE_HUMAN
θ value	3.0926 (rank : 965)	NC score	0.042500 (rank : 1053)
Query Neighborhood Hits	1113	Target Neighborhood Hits	779	Shared Neighborhood Hits	144
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

SFR15_HUMAN
θ value	3.0926 (rank : 966)	NC score	0.019258 (rank : 1178)
Query Neighborhood Hits	1113	Target Neighborhood Hits	368	Shared Neighborhood Hits	64
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SMCA4_HUMAN
θ value	3.0926 (rank : 967)	NC score	0.002872 (rank : 1268)
Query Neighborhood Hits	1113	Target Neighborhood Hits	597	Shared Neighborhood Hits	79
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SPY1_HUMAN
θ value	3.0926 (rank : 968)	NC score	0.042751 (rank : 1052)
Query Neighborhood Hits	1113	Target Neighborhood Hits	64	Shared Neighborhood Hits	44
SwissProt Accessions	O43609, Q6PNE0	Gene names	SPRY1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

SRRM2_MOUSE
θ value	3.0926 (rank : 969)	NC score	0.026577 (rank : 1128)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1470	Shared Neighborhood Hits	187
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TARSH_HUMAN
θ value	3.0926 (rank : 970)	NC score	0.053626 (rank : 993)
Query Neighborhood Hits	1113	Target Neighborhood Hits	768	Shared Neighborhood Hits	217
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TGFA_HUMAN
θ value	3.0926 (rank : 971)	NC score	0.105686 (rank : 783)
Query Neighborhood Hits	1113	Target Neighborhood Hits	61	Shared Neighborhood Hits	58
SwissProt Accessions	P01135, Q15577	Gene names	TGFA
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

TNR1B_HUMAN
θ value	3.0926 (rank : 972)	NC score	0.047516 (rank : 1029)
Query Neighborhood Hits	1113	Target Neighborhood Hits	127	Shared Neighborhood Hits	62
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

WASF1_HUMAN
θ value	3.0926 (rank : 973)	NC score	0.050401 (rank : 1023)
Query Neighborhood Hits	1113	Target Neighborhood Hits	260	Shared Neighborhood Hits	74
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

YAP1_HUMAN
θ value	3.0926 (rank : 974)	NC score	0.006326 (rank : 1243)
Query Neighborhood Hits	1113	Target Neighborhood Hits	173	Shared Neighborhood Hits	38
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

ZEP2_MOUSE
θ value	3.0926 (rank : 975)	NC score	-0.014661 (rank : 1321)
Query Neighborhood Hits	1113	Target Neighborhood Hits	964	Shared Neighborhood Hits	67
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

ZN598_HUMAN
θ value	3.0926 (rank : 976)	NC score	0.008680 (rank : 1237)
Query Neighborhood Hits	1113	Target Neighborhood Hits	339	Shared Neighborhood Hits	44
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

ADA18_HUMAN
θ value	4.03905 (rank : 977)	NC score	0.154872 (rank : 696)
Query Neighborhood Hits	1113	Target Neighborhood Hits	184	Shared Neighborhood Hits	153
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

ADA32_MOUSE
θ value	4.03905 (rank : 978)	NC score	0.144205 (rank : 727)
Query Neighborhood Hits	1113	Target Neighborhood Hits	219	Shared Neighborhood Hits	176
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

AKAP2_HUMAN
θ value	4.03905 (rank : 979)	NC score	0.009303 (rank : 1236)
Query Neighborhood Hits	1113	Target Neighborhood Hits	507	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

AN13C_HUMAN
θ value	4.03905 (rank : 980)	NC score	0.226502 (rank : 585)
Query Neighborhood Hits	1113	Target Neighborhood Hits	241	Shared Neighborhood Hits	232
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

CDN1C_HUMAN
θ value	4.03905 (rank : 981)	NC score	0.018604 (rank : 1185)
Query Neighborhood Hits	1113	Target Neighborhood Hits	168	Shared Neighborhood Hits	37
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CLC14_HUMAN
θ value	4.03905 (rank : 982)	NC score	0.243272 (rank : 567)
Query Neighborhood Hits	1113	Target Neighborhood Hits	143	Shared Neighborhood Hits	119
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

CO039_MOUSE
θ value	4.03905 (rank : 983)	NC score	0.031675 (rank : 1093)
Query Neighborhood Hits	1113	Target Neighborhood Hits	445	Shared Neighborhood Hits	137
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

DAB2_MOUSE
θ value	4.03905 (rank : 984)	NC score	0.013187 (rank : 1216)
Query Neighborhood Hits	1113	Target Neighborhood Hits	163	Shared Neighborhood Hits	43
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

DDFL1_HUMAN
θ value	4.03905 (rank : 985)	NC score	0.171076 (rank : 667)
Query Neighborhood Hits	1113	Target Neighborhood Hits	353	Shared Neighborhood Hits	229
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DSG1C_MOUSE
θ value	4.03905 (rank : 986)	NC score	0.018739 (rank : 1183)
Query Neighborhood Hits	1113	Target Neighborhood Hits	156	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TSF0, Q7TQ61	Gene names	Dsg1c, Dsg6
Domain Architecture	No domain graphic available
Description	Desmoglein-1 gamma precursor (Dsg1-gamma) (Desmoglein-6).

EPHAA_HUMAN
θ value	4.03905 (rank : 987)	NC score	0.018832 (rank : 1182)
Query Neighborhood Hits	1113	Target Neighborhood Hits	960	Shared Neighborhood Hits	114
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

ESM1_MOUSE
θ value	4.03905 (rank : 988)	NC score	0.145998 (rank : 723)
Query Neighborhood Hits	1113	Target Neighborhood Hits	107	Shared Neighborhood Hits	74
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

FMNL_HUMAN
θ value	4.03905 (rank : 989)	NC score	0.022173 (rank : 1161)
Query Neighborhood Hits	1113	Target Neighborhood Hits	529	Shared Neighborhood Hits	75
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

GP128_HUMAN
θ value	4.03905 (rank : 990)	NC score	0.093660 (rank : 805)
Query Neighborhood Hits	1113	Target Neighborhood Hits	135	Shared Neighborhood Hits	53
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

GP128_MOUSE
θ value	4.03905 (rank : 991)	NC score	0.099160 (rank : 795)
Query Neighborhood Hits	1113	Target Neighborhood Hits	141	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BM96, Q80T42	Gene names	Gpr128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

HDAC7_HUMAN
θ value	4.03905 (rank : 992)	NC score	0.002091 (rank : 1274)
Query Neighborhood Hits	1113	Target Neighborhood Hits	64	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WUI4, Q7Z5I1, Q96K01, Q9BR73, Q9H7L0, Q9NW41, Q9NWA9, Q9NYK9, Q9UFU7	Gene names	HDAC7A, HDAC7
Domain Architecture
Description	Histone deacetylase 7a (HD7a).

IGHG3_HUMAN
θ value	4.03905 (rank : 993)	NC score	-0.000158 (rank : 1292)
Query Neighborhood Hits	1113	Target Neighborhood Hits	234	Shared Neighborhood Hits	9
SwissProt Accessions	P01860	Gene names	IGHG3
Domain Architecture
Description	Ig gamma-3 chain C region (Heavy chain disease protein) (HDC).

IRAK1_HUMAN
θ value	4.03905 (rank : 994)	NC score	0.006133 (rank : 1245)
Query Neighborhood Hits	1113	Target Neighborhood Hits	820	Shared Neighborhood Hits	52
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

K1683_HUMAN
θ value	4.03905 (rank : 995)	NC score	0.023367 (rank : 1146)
Query Neighborhood Hits	1113	Target Neighborhood Hits	240	Shared Neighborhood Hits	78
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

MLL2_HUMAN
θ value	4.03905 (rank : 996)	NC score	0.046068 (rank : 1034)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1788	Shared Neighborhood Hits	248
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MUC1_MOUSE
θ value	4.03905 (rank : 997)	NC score	0.021592 (rank : 1167)
Query Neighborhood Hits	1113	Target Neighborhood Hits	388	Shared Neighborhood Hits	66
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

NEU1_MOUSE
θ value	4.03905 (rank : 998)	NC score	0.078065 (rank : 851)
Query Neighborhood Hits	1113	Target Neighborhood Hits	64	Shared Neighborhood Hits	51
SwissProt Accessions	P35454	Gene names	Oxt
Domain Architecture
Description	Oxytocin-neurophysin 1 precursor (OT-NPI) [Contains: Oxytocin (Ocytocin); Neurophysin 1].

NOV_MOUSE
θ value	4.03905 (rank : 999)	NC score	0.061552 (rank : 938)
Query Neighborhood Hits	1113	Target Neighborhood Hits	130	Shared Neighborhood Hits	71
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

PCD15_MOUSE
θ value	4.03905 (rank : 1000)	NC score	0.034085 (rank : 1087)
Query Neighborhood Hits	1113	Target Neighborhood Hits	262	Shared Neighborhood Hits	40
SwissProt Accessions	Q99PJ1	Gene names	Pcdh15
Domain Architecture
Description	Protocadherin-15 precursor.

PI5PA_HUMAN
θ value	4.03905 (rank : 1001)	NC score	0.051261 (rank : 1013)
Query Neighborhood Hits	1113	Target Neighborhood Hits	749	Shared Neighborhood Hits	189
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

S23IP_MOUSE
θ value	4.03905 (rank : 1002)	NC score	0.037894 (rank : 1070)
Query Neighborhood Hits	1113	Target Neighborhood Hits	363	Shared Neighborhood Hits	122
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

SI1L1_HUMAN
θ value	4.03905 (rank : 1003)	NC score	0.001191 (rank : 1280)
Query Neighborhood Hits	1113	Target Neighborhood Hits	162	Shared Neighborhood Hits	8
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

SIM1_HUMAN
θ value	4.03905 (rank : 1004)	NC score	-0.000608 (rank : 1295)
Query Neighborhood Hits	1113	Target Neighborhood Hits	62	Shared Neighborhood Hits	9
SwissProt Accessions	P81133, Q5TDP7	Gene names	SIM1
Domain Architecture
Description	Single-minded homolog 1.

SMRC2_HUMAN
θ value	4.03905 (rank : 1005)	NC score	0.013181 (rank : 1217)
Query Neighborhood Hits	1113	Target Neighborhood Hits	499	Shared Neighborhood Hits	62
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SOX30_MOUSE
θ value	4.03905 (rank : 1006)	NC score	0.014370 (rank : 1211)
Query Neighborhood Hits	1113	Target Neighborhood Hits	374	Shared Neighborhood Hits	100
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

SPRL1_MOUSE
θ value	4.03905 (rank : 1007)	NC score	0.026125 (rank : 1133)
Query Neighborhood Hits	1113	Target Neighborhood Hits	403	Shared Neighborhood Hits	45
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

TMPS2_HUMAN
θ value	4.03905 (rank : 1008)	NC score	0.050938 (rank : 1018)
Query Neighborhood Hits	1113	Target Neighborhood Hits	252	Shared Neighborhood Hits	76
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TNR9_HUMAN
θ value	4.03905 (rank : 1009)	NC score	0.104959 (rank : 785)
Query Neighborhood Hits	1113	Target Neighborhood Hits	166	Shared Neighborhood Hits	87
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TRI42_HUMAN
θ value	4.03905 (rank : 1010)	NC score	0.022781 (rank : 1151)
Query Neighborhood Hits	1113	Target Neighborhood Hits	283	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRPV1_MOUSE
θ value	4.03905 (rank : 1011)	NC score	0.126360 (rank : 760)
Query Neighborhood Hits	1113	Target Neighborhood Hits	189	Shared Neighborhood Hits	150
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

ZN207_HUMAN
θ value	4.03905 (rank : 1012)	NC score	0.030752 (rank : 1098)
Query Neighborhood Hits	1113	Target Neighborhood Hits	326	Shared Neighborhood Hits	51
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

ADA10_MOUSE
θ value	5.27518 (rank : 1013)	NC score	0.154067 (rank : 700)
Query Neighborhood Hits	1113	Target Neighborhood Hits	194	Shared Neighborhood Hits	151
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ALX3_MOUSE
θ value	5.27518 (rank : 1014)	NC score	-0.009339 (rank : 1316)
Query Neighborhood Hits	1113	Target Neighborhood Hits	386	Shared Neighborhood Hits	15
SwissProt Accessions	O70137	Gene names	Alx3
Domain Architecture
Description	Homeobox protein aristaless-like 3 (Proline-rich transcription factor ALX3).

AN13C_MOUSE
θ value	5.27518 (rank : 1015)	NC score	0.220880 (rank : 593)
Query Neighborhood Hits	1113	Target Neighborhood Hits	242	Shared Neighborhood Hits	230
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

ANKR9_MOUSE
θ value	5.27518 (rank : 1016)	NC score	0.148875 (rank : 719)
Query Neighborhood Hits	1113	Target Neighborhood Hits	120	Shared Neighborhood Hits	116
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

AP3B2_HUMAN
θ value	5.27518 (rank : 1017)	NC score	0.002251 (rank : 1272)
Query Neighborhood Hits	1113	Target Neighborhood Hits	246	Shared Neighborhood Hits	25
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

AP3B2_MOUSE
θ value	5.27518 (rank : 1018)	NC score	0.001125 (rank : 1281)
Query Neighborhood Hits	1113	Target Neighborhood Hits	246	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

BT3A1_HUMAN
θ value	5.27518 (rank : 1019)	NC score	0.001483 (rank : 1277)
Query Neighborhood Hits	1113	Target Neighborhood Hits	229	Shared Neighborhood Hits	19
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

DAG1_HUMAN
θ value	5.27518 (rank : 1020)	NC score	0.021965 (rank : 1164)
Query Neighborhood Hits	1113	Target Neighborhood Hits	104	Shared Neighborhood Hits	38
SwissProt Accessions	Q14118	Gene names	DAG1
Domain Architecture
Description	Dystroglycan precursor (Dystrophin-associated glycoprotein 1) [Contains: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta- DG)].

DOT1L_HUMAN
θ value	5.27518 (rank : 1021)	NC score	0.021287 (rank : 1169)
Query Neighborhood Hits	1113	Target Neighborhood Hits	660	Shared Neighborhood Hits	95
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

EGR1_HUMAN
θ value	5.27518 (rank : 1022)	NC score	-0.020236 (rank : 1328)
Query Neighborhood Hits	1113	Target Neighborhood Hits	788	Shared Neighborhood Hits	29
SwissProt Accessions	P18146	Gene names	EGR1, ZNF225
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Zinc finger protein 225) (AT225).

FGD1_HUMAN
θ value	5.27518 (rank : 1023)	NC score	0.005185 (rank : 1247)
Query Neighborhood Hits	1113	Target Neighborhood Hits	367	Shared Neighborhood Hits	55
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FINC_HUMAN
θ value	5.27518 (rank : 1024)	NC score	0.094831 (rank : 803)
Query Neighborhood Hits	1113	Target Neighborhood Hits	302	Shared Neighborhood Hits	72
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FOXL2_HUMAN
θ value	5.27518 (rank : 1025)	NC score	-0.003753 (rank : 1303)
Query Neighborhood Hits	1113	Target Neighborhood Hits	142	Shared Neighborhood Hits	17
SwissProt Accessions	P58012, Q4ZGJ3	Gene names	FOXL2
Domain Architecture
Description	Forkhead box protein L2.

FST_MOUSE
θ value	5.27518 (rank : 1026)	NC score	0.151425 (rank : 713)
Query Neighborhood Hits	1113	Target Neighborhood Hits	146	Shared Neighborhood Hits	90
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

GAK5_HUMAN
θ value	5.27518 (rank : 1027)	NC score	0.011520 (rank : 1223)
Query Neighborhood Hits	1113	Target Neighborhood Hits	429	Shared Neighborhood Hits	128
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GP116_HUMAN
θ value	5.27518 (rank : 1028)	NC score	0.070656 (rank : 878)
Query Neighborhood Hits	1113	Target Neighborhood Hits	167	Shared Neighborhood Hits	38
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

HCN4_HUMAN
θ value	5.27518 (rank : 1029)	NC score	0.003261 (rank : 1263)
Query Neighborhood Hits	1113	Target Neighborhood Hits	303	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HGFL_MOUSE
θ value	5.27518 (rank : 1030)	NC score	0.041948 (rank : 1055)
Query Neighborhood Hits	1113	Target Neighborhood Hits	188	Shared Neighborhood Hits	42
SwissProt Accessions	P26928	Gene names	Mst1, Hgfl
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

HYAL2_HUMAN
θ value	5.27518 (rank : 1031)	NC score	0.020340 (rank : 1173)
Query Neighborhood Hits	1113	Target Neighborhood Hits	24	Shared Neighborhood Hits	16
SwissProt Accessions	Q12891, O15177, Q9BW29	Gene names	HYAL2, LUCA2
Domain Architecture
Description	Hyaluronidase-2 precursor (EC 3.2.1.35) (Hyal-2) (Hyaluronoglucosaminidase-2) (LUCA-2).

JHD2C_MOUSE
θ value	5.27518 (rank : 1032)	NC score	0.003349 (rank : 1262)
Query Neighborhood Hits	1113	Target Neighborhood Hits	297	Shared Neighborhood Hits	27
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

KR111_HUMAN
θ value	5.27518 (rank : 1033)	NC score	0.100789 (rank : 792)
Query Neighborhood Hits	1113	Target Neighborhood Hits	90	Shared Neighborhood Hits	73
SwissProt Accessions	Q8IUC1	Gene names	KRTAP11-1, KAP11.1, KRTAP11.1
Domain Architecture
Description	Keratin-associated protein 11-1 (High sulfur keratin-associated protein 11.1).

KRHB5_MOUSE
θ value	5.27518 (rank : 1034)	NC score	-0.001741 (rank : 1297)
Query Neighborhood Hits	1113	Target Neighborhood Hits	294	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z2T6, Q8CE83, Q9D7M4	Gene names	Krthb5, Krt2-18
Domain Architecture
Description	Keratin, type II cuticular Hb5 (Hair keratin, type II Hb5).

LDB3_MOUSE
θ value	5.27518 (rank : 1035)	NC score	-0.000027 (rank : 1290)
Query Neighborhood Hits	1113	Target Neighborhood Hits	510	Shared Neighborhood Hits	72
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

LRC50_HUMAN
θ value	5.27518 (rank : 1036)	NC score	0.000598 (rank : 1284)
Query Neighborhood Hits	1113	Target Neighborhood Hits	275	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NEP3, Q69YI8, Q69YJ0, Q96LP3	Gene names	LRRC50
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 50.

MCSP_MOUSE
θ value	5.27518 (rank : 1037)	NC score	0.137931 (rank : 740)
Query Neighborhood Hits	1113	Target Neighborhood Hits	108	Shared Neighborhood Hits	65
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MGR1_MOUSE
θ value	5.27518 (rank : 1038)	NC score	0.002902 (rank : 1267)
Query Neighborhood Hits	1113	Target Neighborhood Hits	90	Shared Neighborhood Hits	12
SwissProt Accessions	P97772, Q6AXG4, Q9EPV6	Gene names	Grm1, Gprc1a, Mglur1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

MLL3_HUMAN
θ value	5.27518 (rank : 1039)	NC score	0.065100 (rank : 908)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1644	Shared Neighborhood Hits	313
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MT4_MOUSE
θ value	5.27518 (rank : 1040)	NC score	0.169737 (rank : 674)
Query Neighborhood Hits	1113	Target Neighborhood Hits	102	Shared Neighborhood Hits	79
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MYST3_HUMAN
θ value	5.27518 (rank : 1041)	NC score	0.003635 (rank : 1260)
Query Neighborhood Hits	1113	Target Neighborhood Hits	772	Shared Neighborhood Hits	79
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

NFAC1_HUMAN
θ value	5.27518 (rank : 1042)	NC score	0.017828 (rank : 1190)
Query Neighborhood Hits	1113	Target Neighborhood Hits	312	Shared Neighborhood Hits	101
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

NSD1_HUMAN
θ value	5.27518 (rank : 1043)	NC score	0.020911 (rank : 1171)
Query Neighborhood Hits	1113	Target Neighborhood Hits	427	Shared Neighborhood Hits	76
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

PCSK5_HUMAN
θ value	5.27518 (rank : 1044)	NC score	0.219395 (rank : 596)
Query Neighborhood Hits	1113	Target Neighborhood Hits	291	Shared Neighborhood Hits	193
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

SF3B1_HUMAN
θ value	5.27518 (rank : 1045)	NC score	0.014629 (rank : 1208)
Query Neighborhood Hits	1113	Target Neighborhood Hits	341	Shared Neighborhood Hits	68
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	5.27518 (rank : 1046)	NC score	0.014907 (rank : 1205)
Query Neighborhood Hits	1113	Target Neighborhood Hits	352	Shared Neighborhood Hits	70
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SYNJ1_MOUSE
θ value	5.27518 (rank : 1047)	NC score	0.015096 (rank : 1203)
Query Neighborhood Hits	1113	Target Neighborhood Hits	516	Shared Neighborhood Hits	126
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TROAP_HUMAN
θ value	5.27518 (rank : 1048)	NC score	0.019014 (rank : 1181)
Query Neighborhood Hits	1113	Target Neighborhood Hits	258	Shared Neighborhood Hits	74
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

TYRP1_HUMAN
θ value	5.27518 (rank : 1049)	NC score	0.037227 (rank : 1072)
Query Neighborhood Hits	1113	Target Neighborhood Hits	40	Shared Neighborhood Hits	34
SwissProt Accessions	P17643, P78468, P78469, Q13721, Q15679	Gene names	TYRP1, CAS2, TYRP, TYRRP
Domain Architecture
Description	5,6-dihydroxyindole-2-carboxylic acid oxidase precursor (EC 1.14.18.-) (DHICA oxidase) (Tyrosinase-related protein 1) (TRP-1) (TRP1) (TRP) (Catalase B) (Glycoprotein 75) (Melanoma antigen gp75).

UBP38_HUMAN
θ value	5.27518 (rank : 1050)	NC score	-0.001817 (rank : 1298)
Query Neighborhood Hits	1113	Target Neighborhood Hits	97	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

XRN1_MOUSE
θ value	5.27518 (rank : 1051)	NC score	0.006338 (rank : 1242)
Query Neighborhood Hits	1113	Target Neighborhood Hits	64	Shared Neighborhood Hits	12
SwissProt Accessions	P97789, O35651, P97790, Q3TE44, Q3TRE9, Q3UQL5	Gene names	Xrn1, Dhm2, Exo, Sep1
Domain Architecture	No domain graphic available
Description	5'-3' exoribonuclease 1 (EC 3.1.11.-) (mXRN1) (Strand-exchange protein 1 homolog) (Protein Dhm2).

ZC3H8_HUMAN
θ value	5.27518 (rank : 1052)	NC score	0.001282 (rank : 1279)
Query Neighborhood Hits	1113	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N5P1, Q9BZ75	Gene names	ZC3H8, ZC3HDC8
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 8.

ZCH14_HUMAN
θ value	5.27518 (rank : 1053)	NC score	0.010947 (rank : 1225)
Query Neighborhood Hits	1113	Target Neighborhood Hits	117	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WYQ9, O60324, Q9UFP0	Gene names	ZCCHC14, KIAA0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

ZIM10_MOUSE
θ value	5.27518 (rank : 1054)	NC score	0.017660 (rank : 1191)
Query Neighborhood Hits	1113	Target Neighborhood Hits	430	Shared Neighborhood Hits	109
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ABL1_HUMAN
θ value	6.88961 (rank : 1055)	NC score	0.001963 (rank : 1276)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1220	Shared Neighborhood Hits	91
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ATF5_MOUSE
θ value	6.88961 (rank : 1056)	NC score	0.002142 (rank : 1273)
Query Neighborhood Hits	1113	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	O70191, Q58E51, Q99NH6	Gene names	Atf5, Atfx, Nap1
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-5 (Activating transcription factor 5-alpha/beta) (Transcription factor ATFx) (Transcription factor-like protein ODA-10) (BZIP protein ATF7) (NRIF3- associated protein) (NAP1).

ATS16_MOUSE
θ value	6.88961 (rank : 1057)	NC score	0.045325 (rank : 1038)
Query Neighborhood Hits	1113	Target Neighborhood Hits	179	Shared Neighborhood Hits	92
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS18_HUMAN
θ value	6.88961 (rank : 1058)	NC score	0.046474 (rank : 1033)
Query Neighborhood Hits	1113	Target Neighborhood Hits	169	Shared Neighborhood Hits	88
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

BAT2_MOUSE
θ value	6.88961 (rank : 1059)	NC score	0.034566 (rank : 1083)
Query Neighborhood Hits	1113	Target Neighborhood Hits	947	Shared Neighborhood Hits	188
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CFAI_MOUSE
θ value	6.88961 (rank : 1060)	NC score	0.086952 (rank : 821)
Query Neighborhood Hits	1113	Target Neighborhood Hits	290	Shared Neighborhood Hits	100
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CHCH2_MOUSE
θ value	6.88961 (rank : 1061)	NC score	0.009694 (rank : 1233)
Query Neighborhood Hits	1113	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D1L0, Q3TUG8	Gene names	Chchd2
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 2.

EMID2_MOUSE
θ value	6.88961 (rank : 1062)	NC score	0.026763 (rank : 1127)
Query Neighborhood Hits	1113	Target Neighborhood Hits	201	Shared Neighborhood Hits	50
SwissProt Accessions	Q91VF6, Q8K4P3	Gene names	Emid2, Col26a, Col26a1, Emu2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

EPHA7_HUMAN
θ value	6.88961 (rank : 1063)	NC score	0.029438 (rank : 1112)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1053	Shared Neighborhood Hits	163
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

IL4RA_HUMAN
θ value	6.88961 (rank : 1064)	NC score	0.016055 (rank : 1198)
Query Neighborhood Hits	1113	Target Neighborhood Hits	144	Shared Neighborhood Hits	41
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

MAST2_MOUSE
θ value	6.88961 (rank : 1065)	NC score	-0.006753 (rank : 1313)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1110	Shared Neighborhood Hits	75
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MT3_HUMAN
θ value	6.88961 (rank : 1066)	NC score	0.157486 (rank : 695)
Query Neighborhood Hits	1113	Target Neighborhood Hits	82	Shared Neighborhood Hits	65
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

POLS_MOUSE
θ value	6.88961 (rank : 1067)	NC score	0.006566 (rank : 1241)
Query Neighborhood Hits	1113	Target Neighborhood Hits	91	Shared Neighborhood Hits	37
SwissProt Accessions	Q6PB75	Gene names	Pols
Domain Architecture	No domain graphic available
Description	DNA polymerase sigma (EC 2.7.7.7).

PRG4_MOUSE
θ value	6.88961 (rank : 1068)	NC score	0.028602 (rank : 1116)
Query Neighborhood Hits	1113	Target Neighborhood Hits	624	Shared Neighborhood Hits	100
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RFTN1_HUMAN
θ value	6.88961 (rank : 1069)	NC score	0.003553 (rank : 1261)
Query Neighborhood Hits	1113	Target Neighborhood Hits	72	Shared Neighborhood Hits	10
SwissProt Accessions	Q14699, Q496Y2, Q4QQI7, Q5JB48, Q7Z7P2	Gene names	RFTN1, KIAA0084
Domain Architecture	No domain graphic available
Description	Raftlin (Raft-linking protein) (Cell migration-inducing gene 2 protein).

ROBO3_MOUSE
θ value	6.88961 (rank : 1070)	NC score	0.016502 (rank : 1196)
Query Neighborhood Hits	1113	Target Neighborhood Hits	524	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

SELV_HUMAN
θ value	6.88961 (rank : 1071)	NC score	0.010797 (rank : 1226)
Query Neighborhood Hits	1113	Target Neighborhood Hits	118	Shared Neighborhood Hits	34
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

SON_HUMAN
θ value	6.88961 (rank : 1072)	NC score	0.052197 (rank : 1004)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1568	Shared Neighborhood Hits	276
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SPR2H_MOUSE
θ value	6.88961 (rank : 1073)	NC score	0.082737 (rank : 835)
Query Neighborhood Hits	1113	Target Neighborhood Hits	82	Shared Neighborhood Hits	39
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

TINAL_HUMAN
θ value	6.88961 (rank : 1074)	NC score	0.013371 (rank : 1215)
Query Neighborhood Hits	1113	Target Neighborhood Hits	50	Shared Neighborhood Hits	21
SwissProt Accessions	Q9GZM7, Q8TEJ9, Q8WZ23, Q96GZ4, Q96JW3	Gene names	TINAGL1, GIS5, LCN7, OLRG2, TINAGL
Domain Architecture	No domain graphic available
Description	Tubulointerstitial nephritis antigen-like precursor (Tubulointerstitial nephritis antigen-related protein) (TIN Ag-related protein) (TIN-Ag-RP) (Glucocorticoid-inducible protein 5) (Oxidized LDL-responsive gene 2 protein) (OLRG-2).

TYRP1_MOUSE
θ value	6.88961 (rank : 1075)	NC score	0.040434 (rank : 1062)
Query Neighborhood Hits	1113	Target Neighborhood Hits	43	Shared Neighborhood Hits	37
SwissProt Accessions	P07147	Gene names	Tyrp1, Tyrp-1
Domain Architecture
Description	5,6-dihydroxyindole-2-carboxylic acid oxidase precursor (EC 1.14.18.-) (DHICA oxidase) (Tyrosinase-related protein 1) (TRP-1) (TRP1) (TRP) (Catalase B) (Brown locus protein).

WASL_HUMAN
θ value	6.88961 (rank : 1076)	NC score	0.023933 (rank : 1143)
Query Neighborhood Hits	1113	Target Neighborhood Hits	312	Shared Neighborhood Hits	74
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WNK1_HUMAN
θ value	6.88961 (rank : 1077)	NC score	0.000188 (rank : 1287)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1158	Shared Neighborhood Hits	123
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

ATS6_HUMAN
θ value	8.99809 (rank : 1078)	NC score	0.047687 (rank : 1027)
Query Neighborhood Hits	1113	Target Neighborhood Hits	141	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

ATX2L_HUMAN
θ value	8.99809 (rank : 1079)	NC score	0.015581 (rank : 1200)
Query Neighborhood Hits	1113	Target Neighborhood Hits	443	Shared Neighborhood Hits	100
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

CENPU_HUMAN
θ value	8.99809 (rank : 1080)	NC score	0.010153 (rank : 1232)
Query Neighborhood Hits	1113	Target Neighborhood Hits	289	Shared Neighborhood Hits	20
SwissProt Accessions	Q71F23, Q32Q71, Q9H5G1	Gene names	MLF1IP, CENPU, ICEN24, KLIP1
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (CENP-U(50)) (CENP-50) (Interphase centromere complex protein 24) (MLF1-interacting protein) (KSHV latent nuclear antigen-interacting protein 1).

CNOT3_HUMAN
θ value	8.99809 (rank : 1081)	NC score	0.011687 (rank : 1221)
Query Neighborhood Hits	1113	Target Neighborhood Hits	425	Shared Neighborhood Hits	61
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

DCC_HUMAN
θ value	8.99809 (rank : 1082)	NC score	0.029717 (rank : 1109)
Query Neighborhood Hits	1113	Target Neighborhood Hits	583	Shared Neighborhood Hits	94
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

DDX4_HUMAN
θ value	8.99809 (rank : 1083)	NC score	-0.006582 (rank : 1312)
Query Neighborhood Hits	1113	Target Neighborhood Hits	123	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DGKZ_HUMAN
θ value	8.99809 (rank : 1084)	NC score	0.175252 (rank : 658)
Query Neighborhood Hits	1113	Target Neighborhood Hits	551	Shared Neighborhood Hits	214
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

DMN_HUMAN
θ value	8.99809 (rank : 1085)	NC score	-0.000531 (rank : 1293)
Query Neighborhood Hits	1113	Target Neighborhood Hits	690	Shared Neighborhood Hits	54
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

DMRTD_HUMAN
θ value	8.99809 (rank : 1086)	NC score	0.023645 (rank : 1144)
Query Neighborhood Hits	1113	Target Neighborhood Hits	216	Shared Neighborhood Hits	89
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

DMWD_MOUSE
θ value	8.99809 (rank : 1087)	NC score	-0.004464 (rank : 1306)
Query Neighborhood Hits	1113	Target Neighborhood Hits	282	Shared Neighborhood Hits	18
SwissProt Accessions	Q08274	Gene names	Dmwd, Dm9
Domain Architecture
Description	Dystrophia myotonica WD repeat-containing protein (Dystrophia myotonica-containing WD repeat motif protein) (DMR-N9 protein).

DYN2_MOUSE
θ value	8.99809 (rank : 1088)	NC score	-0.000106 (rank : 1291)
Query Neighborhood Hits	1113	Target Neighborhood Hits	104	Shared Neighborhood Hits	17
SwissProt Accessions	P39054, Q9DBE1	Gene names	Dnm2, Dyn2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM).

FBX46_MOUSE
θ value	8.99809 (rank : 1089)	NC score	0.004530 (rank : 1251)
Query Neighborhood Hits	1113	Target Neighborhood Hits	139	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BG80	Gene names	Fbxo46, Fbx46, Fbxo34l
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

HGF_MOUSE
θ value	8.99809 (rank : 1090)	NC score	0.037065 (rank : 1074)
Query Neighborhood Hits	1113	Target Neighborhood Hits	192	Shared Neighborhood Hits	40
SwissProt Accessions	Q08048, Q61662, Q64007, Q6LBE6	Gene names	Hgf
Domain Architecture
Description	Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain].

K0460_MOUSE
θ value	8.99809 (rank : 1091)	NC score	0.014348 (rank : 1212)
Query Neighborhood Hits	1113	Target Neighborhood Hits	374	Shared Neighborhood Hits	62
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

KRA24_HUMAN
θ value	8.99809 (rank : 1092)	NC score	0.183855 (rank : 648)
Query Neighborhood Hits	1113	Target Neighborhood Hits	192	Shared Neighborhood Hits	140
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

LSD1_MOUSE
θ value	8.99809 (rank : 1093)	NC score	0.006899 (rank : 1239)
Query Neighborhood Hits	1113	Target Neighborhood Hits	224	Shared Neighborhood Hits	27
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

MISS_MOUSE
θ value	8.99809 (rank : 1094)	NC score	0.045030 (rank : 1039)
Query Neighborhood Hits	1113	Target Neighborhood Hits	444	Shared Neighborhood Hits	146
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

MMRN2_HUMAN
θ value	8.99809 (rank : 1095)	NC score	0.024180 (rank : 1142)
Query Neighborhood Hits	1113	Target Neighborhood Hits	400	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H8L6, Q6P2N2	Gene names	MMRN2, EMILIN3
Domain Architecture
Description	Multimerin-2 precursor (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit).

MTSS1_HUMAN
θ value	8.99809 (rank : 1096)	NC score	0.021256 (rank : 1170)
Query Neighborhood Hits	1113	Target Neighborhood Hits	504	Shared Neighborhood Hits	102
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

MYST3_MOUSE
θ value	8.99809 (rank : 1097)	NC score	0.004135 (rank : 1256)
Query Neighborhood Hits	1113	Target Neighborhood Hits	688	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

NEO1_HUMAN
θ value	8.99809 (rank : 1098)	NC score	0.029547 (rank : 1111)
Query Neighborhood Hits	1113	Target Neighborhood Hits	530	Shared Neighborhood Hits	54
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

NSD1_MOUSE
θ value	8.99809 (rank : 1099)	NC score	0.028788 (rank : 1115)
Query Neighborhood Hits	1113	Target Neighborhood Hits	472	Shared Neighborhood Hits	86
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PER3_HUMAN
θ value	8.99809 (rank : 1100)	NC score	0.022624 (rank : 1154)
Query Neighborhood Hits	1113	Target Neighborhood Hits	479	Shared Neighborhood Hits	123
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PHLPP_HUMAN
θ value	8.99809 (rank : 1101)	NC score	0.015229 (rank : 1201)
Query Neighborhood Hits	1113	Target Neighborhood Hits	604	Shared Neighborhood Hits	77
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

PRRT3_MOUSE
θ value	8.99809 (rank : 1102)	NC score	0.018196 (rank : 1189)
Query Neighborhood Hits	1113	Target Neighborhood Hits	162	Shared Neighborhood Hits	28
SwissProt Accessions	Q6PE13	Gene names	Prrt3
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RN123_MOUSE
θ value	8.99809 (rank : 1103)	NC score	0.000133 (rank : 1288)
Query Neighborhood Hits	1113	Target Neighborhood Hits	174	Shared Neighborhood Hits	11
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RSPO2_MOUSE
θ value	8.99809 (rank : 1104)	NC score	0.069773 (rank : 882)
Query Neighborhood Hits	1113	Target Neighborhood Hits	88	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

SOS1_HUMAN
θ value	8.99809 (rank : 1105)	NC score	0.002455 (rank : 1270)
Query Neighborhood Hits	1113	Target Neighborhood Hits	274	Shared Neighborhood Hits	49
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

SPR2G_HUMAN
θ value	8.99809 (rank : 1106)	NC score	0.022491 (rank : 1157)
Query Neighborhood Hits	1113	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BYE4	Gene names	SPRR2G
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G (SPR-2G).

SPRC_HUMAN
θ value	8.99809 (rank : 1107)	NC score	0.049319 (rank : 1025)
Query Neighborhood Hits	1113	Target Neighborhood Hits	45	Shared Neighborhood Hits	27
SwissProt Accessions	P09486	Gene names	SPARC, ON
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

TINAL_MOUSE
θ value	8.99809 (rank : 1108)	NC score	0.016419 (rank : 1197)
Query Neighborhood Hits	1113	Target Neighborhood Hits	52	Shared Neighborhood Hits	21
SwissProt Accessions	Q99JR5, Q9EQT9	Gene names	Tinagl1, Arg1, Lcn7, Tinagl
Domain Architecture	No domain graphic available
Description	Tubulointerstitial nephritis antigen-like precursor (Androgen- regulated gene 1 protein) (Adrenocortical zonation factor 1) (AZ-1) (Tubulointerstitial nephritis antigen-related protein) (TARP).

YETS2_MOUSE
θ value	8.99809 (rank : 1109)	NC score	0.011160 (rank : 1224)
Query Neighborhood Hits	1113	Target Neighborhood Hits	278	Shared Neighborhood Hits	63
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

YLPM1_HUMAN
θ value	8.99809 (rank : 1110)	NC score	0.030490 (rank : 1100)
Query Neighborhood Hits	1113	Target Neighborhood Hits	670	Shared Neighborhood Hits	121
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

ZCH14_MOUSE
θ value	8.99809 (rank : 1111)	NC score	0.013524 (rank : 1214)
Query Neighborhood Hits	1113	Target Neighborhood Hits	109	Shared Neighborhood Hits	31
SwissProt Accessions	Q8VIG0, Q80TX3, Q91VU4	Gene names	Zcchc14, Kiaa0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

ZEP1_HUMAN
θ value	8.99809 (rank : 1112)	NC score	-0.009842 (rank : 1317)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1036	Shared Neighborhood Hits	88
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

ZEP1_MOUSE
θ value	8.99809 (rank : 1113)	NC score	-0.012012 (rank : 1318)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1063	Shared Neighborhood Hits	81
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

ABTB1_HUMAN
θ value	θ > 10 (rank : 1114)	NC score	0.105964 (rank : 782)
Query Neighborhood Hits	1113	Target Neighborhood Hits	325	Shared Neighborhood Hits	156
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

ABTB1_MOUSE
θ value	θ > 10 (rank : 1115)	NC score	0.122149 (rank : 766)
Query Neighborhood Hits	1113	Target Neighborhood Hits	349	Shared Neighborhood Hits	171
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

ADA17_HUMAN
θ value	θ > 10 (rank : 1116)	NC score	0.160480 (rank : 692)
Query Neighborhood Hits	1113	Target Neighborhood Hits	223	Shared Neighborhood Hits	166
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ADA17_MOUSE
θ value	θ > 10 (rank : 1117)	NC score	0.131372 (rank : 754)
Query Neighborhood Hits	1113	Target Neighborhood Hits	201	Shared Neighborhood Hits	153
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

ADEC1_HUMAN
θ value	θ > 10 (rank : 1118)	NC score	0.067211 (rank : 898)
Query Neighborhood Hits	1113	Target Neighborhood Hits	80	Shared Neighborhood Hits	46
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADEC1_MOUSE
θ value	θ > 10 (rank : 1119)	NC score	0.070470 (rank : 879)
Query Neighborhood Hits	1113	Target Neighborhood Hits	85	Shared Neighborhood Hits	53
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ANKF1_HUMAN
θ value	θ > 10 (rank : 1120)	NC score	0.067376 (rank : 896)
Query Neighborhood Hits	1113	Target Neighborhood Hits	126	Shared Neighborhood Hits	79
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

ANKR9_HUMAN
θ value	θ > 10 (rank : 1121)	NC score	0.118830 (rank : 770)
Query Neighborhood Hits	1113	Target Neighborhood Hits	99	Shared Neighborhood Hits	97
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ANR45_HUMAN
θ value	θ > 10 (rank : 1122)	NC score	0.239199 (rank : 570)
Query Neighborhood Hits	1113	Target Neighborhood Hits	201	Shared Neighborhood Hits	178
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ANR45_MOUSE
θ value	θ > 10 (rank : 1123)	NC score	0.252309 (rank : 551)
Query Neighborhood Hits	1113	Target Neighborhood Hits	204	Shared Neighborhood Hits	183
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ASTN_HUMAN
θ value	θ > 10 (rank : 1124)	NC score	0.150889 (rank : 715)
Query Neighborhood Hits	1113	Target Neighborhood Hits	105	Shared Neighborhood Hits	83
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

ASTN_MOUSE
θ value	θ > 10 (rank : 1125)	NC score	0.149375 (rank : 718)
Query Neighborhood Hits	1113	Target Neighborhood Hits	98	Shared Neighborhood Hits	79
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

ATS20_HUMAN
θ value	θ > 10 (rank : 1126)	NC score	0.051794 (rank : 1008)
Query Neighborhood Hits	1113	Target Neighborhood Hits	192	Shared Neighborhood Hits	98
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS20_MOUSE
θ value	θ > 10 (rank : 1127)	NC score	0.057268 (rank : 958)
Query Neighborhood Hits	1113	Target Neighborhood Hits	225	Shared Neighborhood Hits	113
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS9_HUMAN
θ value	θ > 10 (rank : 1128)	NC score	0.061821 (rank : 936)
Query Neighborhood Hits	1113	Target Neighborhood Hits	219	Shared Neighborhood Hits	121
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

BAI2_HUMAN
θ value	θ > 10 (rank : 1129)	NC score	0.083789 (rank : 831)
Query Neighborhood Hits	1113	Target Neighborhood Hits	332	Shared Neighborhood Hits	98
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_MOUSE
θ value	θ > 10 (rank : 1130)	NC score	0.085001 (rank : 826)
Query Neighborhood Hits	1113	Target Neighborhood Hits	323	Shared Neighborhood Hits	94
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI3_HUMAN
θ value	θ > 10 (rank : 1131)	NC score	0.086210 (rank : 823)
Query Neighborhood Hits	1113	Target Neighborhood Hits	246	Shared Neighborhood Hits	76
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
θ value	θ > 10 (rank : 1132)	NC score	0.088682 (rank : 819)
Query Neighborhood Hits	1113	Target Neighborhood Hits	250	Shared Neighborhood Hits	79
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAT4_HUMAN
θ value	θ > 10 (rank : 1133)	NC score	0.103435 (rank : 788)
Query Neighborhood Hits	1113	Target Neighborhood Hits	157	Shared Neighborhood Hits	108
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

BAT4_MOUSE
θ value	θ > 10 (rank : 1134)	NC score	0.123155 (rank : 765)
Query Neighborhood Hits	1113	Target Neighborhood Hits	171	Shared Neighborhood Hits	120
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

CD320_HUMAN
θ value	θ > 10 (rank : 1135)	NC score	0.152301 (rank : 710)
Query Neighborhood Hits	1113	Target Neighborhood Hits	103	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

CFAB_HUMAN
θ value	θ > 10 (rank : 1136)	NC score	0.055979 (rank : 970)
Query Neighborhood Hits	1113	Target Neighborhood Hits	251	Shared Neighborhood Hits	63
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAB_MOUSE
θ value	θ > 10 (rank : 1137)	NC score	0.062544 (rank : 929)
Query Neighborhood Hits	1113	Target Neighborhood Hits	262	Shared Neighborhood Hits	72
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAI_HUMAN
θ value	θ > 10 (rank : 1138)	NC score	0.082337 (rank : 837)
Query Neighborhood Hits	1113	Target Neighborhood Hits	289	Shared Neighborhood Hits	94
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CHRD_HUMAN
θ value	θ > 10 (rank : 1139)	NC score	0.081457 (rank : 842)
Query Neighborhood Hits	1113	Target Neighborhood Hits	102	Shared Neighborhood Hits	66
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

CHRD_MOUSE
θ value	θ > 10 (rank : 1140)	NC score	0.075875 (rank : 859)
Query Neighborhood Hits	1113	Target Neighborhood Hits	102	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

CMTA1_HUMAN
θ value	θ > 10 (rank : 1141)	NC score	0.089286 (rank : 816)
Query Neighborhood Hits	1113	Target Neighborhood Hits	217	Shared Neighborhood Hits	115
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

CO2_HUMAN
θ value	θ > 10 (rank : 1142)	NC score	0.053232 (rank : 994)
Query Neighborhood Hits	1113	Target Neighborhood Hits	258	Shared Neighborhood Hits	71
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO2_MOUSE
θ value	θ > 10 (rank : 1143)	NC score	0.050667 (rank : 1022)
Query Neighborhood Hits	1113	Target Neighborhood Hits	250	Shared Neighborhood Hits	69
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO7A1_HUMAN
θ value	θ > 10 (rank : 1144)	NC score	0.054139 (rank : 986)
Query Neighborhood Hits	1113	Target Neighborhood Hits	807	Shared Neighborhood Hits	134
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

COCA1_HUMAN
θ value	θ > 10 (rank : 1145)	NC score	0.067214 (rank : 897)
Query Neighborhood Hits	1113	Target Neighborhood Hits	458	Shared Neighborhood Hits	72
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COCA1_MOUSE
θ value	θ > 10 (rank : 1146)	NC score	0.071098 (rank : 876)
Query Neighborhood Hits	1113	Target Neighborhood Hits	467	Shared Neighborhood Hits	80
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COEA1_HUMAN
θ value	θ > 10 (rank : 1147)	NC score	0.061200 (rank : 939)
Query Neighborhood Hits	1113	Target Neighborhood Hits	427	Shared Neighborhood Hits	62
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

COEA1_MOUSE
θ value	θ > 10 (rank : 1148)	NC score	0.064113 (rank : 915)
Query Neighborhood Hits	1113	Target Neighborhood Hits	402	Shared Neighborhood Hits	63
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

COKA1_HUMAN
θ value	θ > 10 (rank : 1149)	NC score	0.067662 (rank : 892)
Query Neighborhood Hits	1113	Target Neighborhood Hits	403	Shared Neighborhood Hits	80
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

CRAC1_HUMAN
θ value	θ > 10 (rank : 1150)	NC score	0.278577 (rank : 509)
Query Neighborhood Hits	1113	Target Neighborhood Hits	111	Shared Neighborhood Hits	96
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRAC1_MOUSE
θ value	θ > 10 (rank : 1151)	NC score	0.280650 (rank : 505)
Query Neighborhood Hits	1113	Target Neighborhood Hits	112	Shared Neighborhood Hits	97
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRDL1_HUMAN
θ value	θ > 10 (rank : 1152)	NC score	0.056447 (rank : 963)
Query Neighborhood Hits	1113	Target Neighborhood Hits	75	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BU40, Q9Y3H7	Gene names	CHRDL1, NRLN1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CRDL1_MOUSE
θ value	θ > 10 (rank : 1153)	NC score	0.057371 (rank : 957)
Query Neighborhood Hits	1113	Target Neighborhood Hits	81	Shared Neighborhood Hits	51
SwissProt Accessions	Q920C1, Q924K0, Q9EPZ9	Gene names	Chrdl1, Ng1, Nrln1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CRDL2_HUMAN
θ value	θ > 10 (rank : 1154)	NC score	0.073876 (rank : 865)
Query Neighborhood Hits	1113	Target Neighborhood Hits	99	Shared Neighborhood Hits	59
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

CRDL2_MOUSE
θ value	θ > 10 (rank : 1155)	NC score	0.076096 (rank : 858)
Query Neighborhood Hits	1113	Target Neighborhood Hits	81	Shared Neighborhood Hits	56
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

CSMD1_MOUSE
θ value	θ > 10 (rank : 1156)	NC score	0.071284 (rank : 873)
Query Neighborhood Hits	1113	Target Neighborhood Hits	193	Shared Neighborhood Hits	84
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD2_HUMAN
θ value	θ > 10 (rank : 1157)	NC score	0.063077 (rank : 923)
Query Neighborhood Hits	1113	Target Neighborhood Hits	188	Shared Neighborhood Hits	72
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CSMD3_HUMAN
θ value	θ > 10 (rank : 1158)	NC score	0.069832 (rank : 881)
Query Neighborhood Hits	1113	Target Neighborhood Hits	199	Shared Neighborhood Hits	76
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CSPG4_HUMAN
θ value	θ > 10 (rank : 1159)	NC score	0.059015 (rank : 950)
Query Neighborhood Hits	1113	Target Neighborhood Hits	112	Shared Neighborhood Hits	44
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

CSPG4_MOUSE
θ value	θ > 10 (rank : 1160)	NC score	0.059853 (rank : 944)
Query Neighborhood Hits	1113	Target Neighborhood Hits	105	Shared Neighborhood Hits	46
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

CSPG5_HUMAN
θ value	θ > 10 (rank : 1161)	NC score	0.059136 (rank : 949)
Query Neighborhood Hits	1113	Target Neighborhood Hits	199	Shared Neighborhood Hits	86
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

CT127_HUMAN
θ value	θ > 10 (rank : 1162)	NC score	0.091782 (rank : 809)
Query Neighborhood Hits	1113	Target Neighborhood Hits	67	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

CU081_HUMAN
θ value	θ > 10 (rank : 1163)	NC score	0.059183 (rank : 947)
Query Neighborhood Hits	1113	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

CUZD1_HUMAN
θ value	θ > 10 (rank : 1164)	NC score	0.051234 (rank : 1014)
Query Neighborhood Hits	1113	Target Neighborhood Hits	89	Shared Neighborhood Hits	35
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

DCBD1_HUMAN
θ value	θ > 10 (rank : 1165)	NC score	0.057404 (rank : 956)
Query Neighborhood Hits	1113	Target Neighborhood Hits	110	Shared Neighborhood Hits	44
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD2_HUMAN
θ value	θ > 10 (rank : 1166)	NC score	0.055571 (rank : 975)
Query Neighborhood Hits	1113	Target Neighborhood Hits	118	Shared Neighborhood Hits	42
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

DCBD2_MOUSE
θ value	θ > 10 (rank : 1167)	NC score	0.053806 (rank : 990)
Query Neighborhood Hits	1113	Target Neighborhood Hits	113	Shared Neighborhood Hits	42
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

DDEF1_MOUSE
θ value	θ > 10 (rank : 1168)	NC score	0.135642 (rank : 746)
Query Neighborhood Hits	1113	Target Neighborhood Hits	592	Shared Neighborhood Hits	234
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DKK3_HUMAN
θ value	θ > 10 (rank : 1169)	NC score	0.084568 (rank : 829)
Query Neighborhood Hits	1113	Target Neighborhood Hits	74	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UBP4, Q9ULB7	Gene names	DKK3, REIC
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3).

DKK3_MOUSE
θ value	θ > 10 (rank : 1170)	NC score	0.095959 (rank : 801)
Query Neighborhood Hits	1113	Target Neighborhood Hits	83	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

ENTK_HUMAN
θ value	θ > 10 (rank : 1171)	NC score	0.066974 (rank : 900)
Query Neighborhood Hits	1113	Target Neighborhood Hits	310	Shared Neighborhood Hits	97
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

ENTK_MOUSE
θ value	θ > 10 (rank : 1172)	NC score	0.070947 (rank : 877)
Query Neighborhood Hits	1113	Target Neighborhood Hits	338	Shared Neighborhood Hits	104
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

GLSL_HUMAN
θ value	θ > 10 (rank : 1173)	NC score	0.222700 (rank : 589)
Query Neighborhood Hits	1113	Target Neighborhood Hits	211	Shared Neighborhood Hits	195
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

GLSL_MOUSE
θ value	θ > 10 (rank : 1174)	NC score	0.219182 (rank : 597)
Query Neighborhood Hits	1113	Target Neighborhood Hits	212	Shared Neighborhood Hits	195
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

GLU2B_HUMAN
θ value	θ > 10 (rank : 1175)	NC score	0.052810 (rank : 1000)
Query Neighborhood Hits	1113	Target Neighborhood Hits	377	Shared Neighborhood Hits	56
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

GP110_HUMAN
θ value	θ > 10 (rank : 1176)	NC score	0.062148 (rank : 932)
Query Neighborhood Hits	1113	Target Neighborhood Hits	87	Shared Neighborhood Hits	28
SwissProt Accessions	Q5T601, Q5KU15, Q5T5Z9, Q86SM1, Q8IXE3, Q8IZF8, Q96DQ1	Gene names	GPR110, PGR19
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 110 precursor (G-protein coupled receptor PGR19) (G-protein coupled receptor KPG_012).

GP110_MOUSE
θ value	θ > 10 (rank : 1177)	NC score	0.062185 (rank : 931)
Query Neighborhood Hits	1113	Target Neighborhood Hits	92	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VEC3, Q8BMV8	Gene names	Gpr110
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 110 precursor.

GP111_HUMAN
θ value	θ > 10 (rank : 1178)	NC score	0.056362 (rank : 964)
Query Neighborhood Hits	1113	Target Neighborhood Hits	77	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IZF7, Q86SL6, Q8NGU5, Q8TDT5	Gene names	GPR111, PGR20
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 111 (G-protein coupled receptor PGR20).

GP112_HUMAN
θ value	θ > 10 (rank : 1179)	NC score	0.075027 (rank : 862)
Query Neighborhood Hits	1113	Target Neighborhood Hits	441	Shared Neighborhood Hits	87
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

GP113_HUMAN
θ value	θ > 10 (rank : 1180)	NC score	0.080557 (rank : 847)
Query Neighborhood Hits	1113	Target Neighborhood Hits	102	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IZF5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3	Gene names	GPR113, PGR23
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 113 precursor (G-protein coupled receptor PGR23).

GP114_HUMAN
θ value	θ > 10 (rank : 1181)	NC score	0.068359 (rank : 889)
Query Neighborhood Hits	1113	Target Neighborhood Hits	75	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IZF4, Q6ZMH7, Q6ZML4, Q86SL8, Q8IZ14	Gene names	GPR114, PGR27
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 114 precursor (G-protein coupled receptor PGR27).

GP115_HUMAN
θ value	θ > 10 (rank : 1182)	NC score	0.058394 (rank : 953)
Query Neighborhood Hits	1113	Target Neighborhood Hits	87	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IZF3, Q5T5B5, Q5T5B6, Q86SN9, Q8IXE6	Gene names	GPR115, PGR18
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 (G-protein coupled receptor PGR18).

GP115_MOUSE
θ value	θ > 10 (rank : 1183)	NC score	0.060129 (rank : 943)
Query Neighborhood Hits	1113	Target Neighborhood Hits	69	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D2L6	Gene names	Gpr115
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 precursor.

GP123_HUMAN
θ value	θ > 10 (rank : 1184)	NC score	0.056166 (rank : 967)
Query Neighborhood Hits	1113	Target Neighborhood Hits	120	Shared Neighborhood Hits	34
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

GP124_HUMAN
θ value	θ > 10 (rank : 1185)	NC score	0.065060 (rank : 909)
Query Neighborhood Hits	1113	Target Neighborhood Hits	304	Shared Neighborhood Hits	40
SwissProt Accessions	Q96PE1, Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4	Gene names	GPR124, KIAA1531, TEM5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GP124_MOUSE
θ value	θ > 10 (rank : 1186)	NC score	0.068106 (rank : 891)
Query Neighborhood Hits	1113	Target Neighborhood Hits	423	Shared Neighborhood Hits	52
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GP125_HUMAN
θ value	θ > 10 (rank : 1187)	NC score	0.068726 (rank : 887)
Query Neighborhood Hits	1113	Target Neighborhood Hits	327	Shared Neighborhood Hits	38
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

GP125_MOUSE
θ value	θ > 10 (rank : 1188)	NC score	0.064652 (rank : 911)
Query Neighborhood Hits	1113	Target Neighborhood Hits	329	Shared Neighborhood Hits	40
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

GP126_HUMAN
θ value	θ > 10 (rank : 1189)	NC score	0.081086 (rank : 846)
Query Neighborhood Hits	1113	Target Neighborhood Hits	187	Shared Neighborhood Hits	48
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

GP133_HUMAN
θ value	θ > 10 (rank : 1190)	NC score	0.073605 (rank : 866)
Query Neighborhood Hits	1113	Target Neighborhood Hits	115	Shared Neighborhood Hits	20
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

GP144_HUMAN
θ value	θ > 10 (rank : 1191)	NC score	0.075854 (rank : 860)
Query Neighborhood Hits	1113	Target Neighborhood Hits	108	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

GPR56_HUMAN
θ value	θ > 10 (rank : 1192)	NC score	0.063973 (rank : 916)
Query Neighborhood Hits	1113	Target Neighborhood Hits	84	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y653, O95966, Q8NGB3, Q96HB4	Gene names	GPR56, TM7LN4, TM7XN1
Domain Architecture
Description	G-protein coupled receptor 56 precursor (TM7XN1 protein).

GPR56_MOUSE
θ value	θ > 10 (rank : 1193)	NC score	0.063897 (rank : 917)
Query Neighborhood Hits	1113	Target Neighborhood Hits	89	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K209, Q3UR17, Q9QZT2	Gene names	Gpr56, Cyt28
Domain Architecture
Description	G-protein coupled receptor 56 precursor (Serpentine receptor cyt28).

GPR64_HUMAN
θ value	θ > 10 (rank : 1194)	NC score	0.068515 (rank : 888)
Query Neighborhood Hits	1113	Target Neighborhood Hits	207	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

GPR64_MOUSE
θ value	θ > 10 (rank : 1195)	NC score	0.069527 (rank : 883)
Query Neighborhood Hits	1113	Target Neighborhood Hits	156	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

GPR97_HUMAN
θ value	θ > 10 (rank : 1196)	NC score	0.058740 (rank : 952)
Query Neighborhood Hits	1113	Target Neighborhood Hits	86	Shared Neighborhood Hits	20
SwissProt Accessions	Q86Y34, Q6ZMF4, Q86SL9, Q8IZF1	Gene names	GPR97, PGR26
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor (G-protein coupled receptor PGR26).

GPR97_MOUSE
θ value	θ > 10 (rank : 1197)	NC score	0.064427 (rank : 912)
Query Neighborhood Hits	1113	Target Neighborhood Hits	89	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R0T6	Gene names	Gpr97
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor.

GPR98_HUMAN
θ value	θ > 10 (rank : 1198)	NC score	0.055281 (rank : 980)
Query Neighborhood Hits	1113	Target Neighborhood Hits	202	Shared Neighborhood Hits	38
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

GPR98_MOUSE
θ value	θ > 10 (rank : 1199)	NC score	0.052387 (rank : 1003)
Query Neighborhood Hits	1113	Target Neighborhood Hits	206	Shared Neighborhood Hits	36
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

HPLN1_HUMAN
θ value	θ > 10 (rank : 1200)	NC score	0.062871 (rank : 928)
Query Neighborhood Hits	1113	Target Neighborhood Hits	67	Shared Neighborhood Hits	13
SwissProt Accessions	P10915	Gene names	HAPLN1, CRTL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

HPLN1_MOUSE
θ value	θ > 10 (rank : 1201)	NC score	0.062891 (rank : 926)
Query Neighborhood Hits	1113	Target Neighborhood Hits	64	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QUP5, Q9D1G9, Q9Z1X7	Gene names	Hapln1, Crtl1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

HPLN2_HUMAN
θ value	θ > 10 (rank : 1202)	NC score	0.065298 (rank : 907)
Query Neighborhood Hits	1113	Target Neighborhood Hits	80	Shared Neighborhood Hits	15
SwissProt Accessions	Q9GZV7	Gene names	HAPLN2, BRAL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

HPLN2_MOUSE
θ value	θ > 10 (rank : 1203)	NC score	0.066168 (rank : 904)
Query Neighborhood Hits	1113	Target Neighborhood Hits	102	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ESM3	Gene names	Hapln2, Bral1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

HPLN3_HUMAN
θ value	θ > 10 (rank : 1204)	NC score	0.063878 (rank : 918)
Query Neighborhood Hits	1113	Target Neighborhood Hits	70	Shared Neighborhood Hits	12
SwissProt Accessions	Q96S86	Gene names	HAPLN3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor.

HPLN3_MOUSE
θ value	θ > 10 (rank : 1205)	NC score	0.065367 (rank : 906)
Query Neighborhood Hits	1113	Target Neighborhood Hits	95	Shared Neighborhood Hits	13
SwissProt Accessions	Q80WM5, Q80XX3	Gene names	Hapln3, Lpr3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor (Link protein 3).

HPLN4_HUMAN
θ value	θ > 10 (rank : 1206)	NC score	0.062519 (rank : 930)
Query Neighborhood Hits	1113	Target Neighborhood Hits	100	Shared Neighborhood Hits	15
SwissProt Accessions	Q86UW8, Q96PW2	Gene names	HAPLN4, BRAL2, KIAA1926
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2).

HPLN4_MOUSE
θ value	θ > 10 (rank : 1207)	NC score	0.063079 (rank : 922)
Query Neighborhood Hits	1113	Target Neighborhood Hits	98	Shared Neighborhood Hits	16
SwissProt Accessions	Q80WM4, Q80XX2	Gene names	Hapln4, Bral2, Lpr4
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2) (Link protein 4).

IDD_HUMAN
θ value	θ > 10 (rank : 1208)	NC score	0.076252 (rank : 856)
Query Neighborhood Hits	1113	Target Neighborhood Hits	127	Shared Neighborhood Hits	55
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

IDD_MOUSE
θ value	θ > 10 (rank : 1209)	NC score	0.071388 (rank : 872)
Query Neighborhood Hits	1113	Target Neighborhood Hits	151	Shared Neighborhood Hits	56
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

KR122_HUMAN
θ value	θ > 10 (rank : 1210)	NC score	0.123468 (rank : 764)
Query Neighborhood Hits	1113	Target Neighborhood Hits	97	Shared Neighborhood Hits	75
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

KR123_HUMAN
θ value	θ > 10 (rank : 1211)	NC score	0.089855 (rank : 813)
Query Neighborhood Hits	1113	Target Neighborhood Hits	75	Shared Neighborhood Hits	55
SwissProt Accessions	P60328	Gene names	KRTAP12-3, KAP12.3, KRTAP12.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-3 (Keratin-associated protein 12.3) (High sulfur keratin-associated protein 12.3).

KR131_HUMAN
θ value	θ > 10 (rank : 1212)	NC score	0.067471 (rank : 895)
Query Neighborhood Hits	1113	Target Neighborhood Hits	123	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IUC0, Q3LI79	Gene names	KRTAP13-1, KAP13.1, KRTAP13.1
Domain Architecture
Description	Keratin-associated protein 13-1 (High sulfur keratin-associated protein 13.1).

KR132_HUMAN
θ value	θ > 10 (rank : 1213)	NC score	0.056112 (rank : 968)
Query Neighborhood Hits	1113	Target Neighborhood Hits	69	Shared Neighborhood Hits	52
SwissProt Accessions	Q52LG2	Gene names	KRTAP13-2, KAP13.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-2.

KR133_HUMAN
θ value	θ > 10 (rank : 1214)	NC score	0.056167 (rank : 966)
Query Neighborhood Hits	1113	Target Neighborhood Hits	66	Shared Neighborhood Hits	55
SwissProt Accessions	Q3SY46, Q3LI78	Gene names	KRTAP13-3, KAP13.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-3.

KR134_HUMAN
θ value	θ > 10 (rank : 1215)	NC score	0.063667 (rank : 919)
Query Neighborhood Hits	1113	Target Neighborhood Hits	81	Shared Neighborhood Hits	56
SwissProt Accessions	Q3LI77	Gene names	KRTAP13-4, KAP13.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-4.

KR221_HUMAN
θ value	θ > 10 (rank : 1216)	NC score	0.051793 (rank : 1009)
Query Neighborhood Hits	1113	Target Neighborhood Hits	6	Shared Neighborhood Hits	5
SwissProt Accessions	Q3MIV0	Gene names	KRTAP22-1, KAP22.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 22-1.

KR241_HUMAN
θ value	θ > 10 (rank : 1217)	NC score	0.081257 (rank : 844)
Query Neighborhood Hits	1113	Target Neighborhood Hits	71	Shared Neighborhood Hits	53
SwissProt Accessions	Q3LI83	Gene names	KRTAP24-1, KAP24.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 24-1.

KR261_HUMAN
θ value	θ > 10 (rank : 1218)	NC score	0.078292 (rank : 850)
Query Neighborhood Hits	1113	Target Neighborhood Hits	65	Shared Neighborhood Hits	49
SwissProt Accessions	Q6PEX3	Gene names	KRTAP26-1, KAP26.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 26-1.

KREM1_HUMAN
θ value	θ > 10 (rank : 1219)	NC score	0.053948 (rank : 989)
Query Neighborhood Hits	1113	Target Neighborhood Hits	90	Shared Neighborhood Hits	40
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM1_MOUSE
θ value	θ > 10 (rank : 1220)	NC score	0.056909 (rank : 960)
Query Neighborhood Hits	1113	Target Neighborhood Hits	92	Shared Neighborhood Hits	43
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM2_HUMAN
θ value	θ > 10 (rank : 1221)	NC score	0.055682 (rank : 973)
Query Neighborhood Hits	1113	Target Neighborhood Hits	93	Shared Neighborhood Hits	45
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

KREM2_MOUSE
θ value	θ > 10 (rank : 1222)	NC score	0.052607 (rank : 1001)
Query Neighborhood Hits	1113	Target Neighborhood Hits	90	Shared Neighborhood Hits	42
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

LCE2A_HUMAN
θ value	θ > 10 (rank : 1223)	NC score	0.132604 (rank : 751)
Query Neighborhood Hits	1113	Target Neighborhood Hits	50	Shared Neighborhood Hits	31
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

LCE2B_HUMAN
θ value	θ > 10 (rank : 1224)	NC score	0.127356 (rank : 759)
Query Neighborhood Hits	1113	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

LCE2C_HUMAN
θ value	θ > 10 (rank : 1225)	NC score	0.152524 (rank : 709)
Query Neighborhood Hits	1113	Target Neighborhood Hits	53	Shared Neighborhood Hits	33
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LCE2D_HUMAN
θ value	θ > 10 (rank : 1226)	NC score	0.138877 (rank : 738)
Query Neighborhood Hits	1113	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

LCE3A_HUMAN
θ value	θ > 10 (rank : 1227)	NC score	0.185296 (rank : 646)
Query Neighborhood Hits	1113	Target Neighborhood Hits	29	Shared Neighborhood Hits	26
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

LCE3B_HUMAN
θ value	θ > 10 (rank : 1228)	NC score	0.120735 (rank : 769)
Query Neighborhood Hits	1113	Target Neighborhood Hits	47	Shared Neighborhood Hits	36
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

LCE4A_HUMAN
θ value	θ > 10 (rank : 1229)	NC score	0.139618 (rank : 736)
Query Neighborhood Hits	1113	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

LCE5A_HUMAN
θ value	θ > 10 (rank : 1230)	NC score	0.092407 (rank : 808)
Query Neighborhood Hits	1113	Target Neighborhood Hits	43	Shared Neighborhood Hits	22
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

LORI_MOUSE
θ value	θ > 10 (rank : 1231)	NC score	0.127948 (rank : 757)
Query Neighborhood Hits	1113	Target Neighborhood Hits	47	Shared Neighborhood Hits	21
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

LPHN1_HUMAN
θ value	θ > 10 (rank : 1232)	NC score	0.071393 (rank : 871)
Query Neighborhood Hits	1113	Target Neighborhood Hits	155	Shared Neighborhood Hits	27
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

LPHN2_HUMAN
θ value	θ > 10 (rank : 1233)	NC score	0.072126 (rank : 869)
Query Neighborhood Hits	1113	Target Neighborhood Hits	136	Shared Neighborhood Hits	24
SwissProt Accessions	O95490, O94882, Q5VX76, Q9UKY5, Q9UKY6	Gene names	LPHN2, KIAA0786, LEC1, LPHH1
Domain Architecture
Description	Latrophilin-2 precursor (Calcium-independent alpha-latrotoxin receptor 2) (Latrophilin homolog 1) (Lectomedin-1).

LPHN3_HUMAN
θ value	θ > 10 (rank : 1234)	NC score	0.071490 (rank : 870)
Query Neighborhood Hits	1113	Target Neighborhood Hits	139	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

LRP10_MOUSE
θ value	θ > 10 (rank : 1235)	NC score	0.136589 (rank : 745)
Query Neighborhood Hits	1113	Target Neighborhood Hits	169	Shared Neighborhood Hits	102
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP11_HUMAN
θ value	θ > 10 (rank : 1236)	NC score	0.051186 (rank : 1015)
Query Neighborhood Hits	1113	Target Neighborhood Hits	82	Shared Neighborhood Hits	39
SwissProt Accessions	Q86VZ4, Q5VYC0, Q96SN6	Gene names	LRP11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

LRP11_MOUSE
θ value	θ > 10 (rank : 1237)	NC score	0.054175 (rank : 985)
Query Neighborhood Hits	1113	Target Neighborhood Hits	81	Shared Neighborhood Hits	42
SwissProt Accessions	Q8CB67, Q8C7Y7	Gene names	Lrp11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

LRP12_HUMAN
θ value	θ > 10 (rank : 1238)	NC score	0.135103 (rank : 747)
Query Neighborhood Hits	1113	Target Neighborhood Hits	205	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
θ value	θ > 10 (rank : 1239)	NC score	0.133894 (rank : 750)
Query Neighborhood Hits	1113	Target Neighborhood Hits	180	Shared Neighborhood Hits	107
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

MFAP4_HUMAN
θ value	θ > 10 (rank : 1240)	NC score	0.050849 (rank : 1020)
Query Neighborhood Hits	1113	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	P55083, Q6P680	Gene names	MFAP4
Domain Architecture
Description	Microfibril-associated glycoprotein 4 precursor.

MFAP4_MOUSE
θ value	θ > 10 (rank : 1241)	NC score	0.050910 (rank : 1019)
Query Neighborhood Hits	1113	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D1H9, Q5NCN1	Gene names	Mfap4
Domain Architecture	No domain graphic available
Description	Microfibril-associated glycoprotein 4 precursor.

MFRP_MOUSE
θ value	θ > 10 (rank : 1242)	NC score	0.069017 (rank : 884)
Query Neighborhood Hits	1113	Target Neighborhood Hits	166	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MT1A_HUMAN
θ value	θ > 10 (rank : 1243)	NC score	0.088880 (rank : 818)
Query Neighborhood Hits	1113	Target Neighborhood Hits	74	Shared Neighborhood Hits	56
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

MT1E_HUMAN
θ value	θ > 10 (rank : 1244)	NC score	0.058991 (rank : 951)
Query Neighborhood Hits	1113	Target Neighborhood Hits	75	Shared Neighborhood Hits	55
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

MT1F_HUMAN
θ value	θ > 10 (rank : 1245)	NC score	0.052023 (rank : 1005)
Query Neighborhood Hits	1113	Target Neighborhood Hits	73	Shared Neighborhood Hits	52
SwissProt Accessions	P04733, Q9UI97	Gene names	MT1F
Domain Architecture	No domain graphic available
Description	Metallothionein-1F (MT-1F) (Metallothionein-IF) (MT-IF).

MT1H_HUMAN
θ value	θ > 10 (rank : 1246)	NC score	0.074343 (rank : 863)
Query Neighborhood Hits	1113	Target Neighborhood Hits	78	Shared Neighborhood Hits	56
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

MT1X_HUMAN
θ value	θ > 10 (rank : 1247)	NC score	0.082852 (rank : 833)
Query Neighborhood Hits	1113	Target Neighborhood Hits	76	Shared Neighborhood Hits	55
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

MT1_MOUSE
θ value	θ > 10 (rank : 1248)	NC score	0.075335 (rank : 861)
Query Neighborhood Hits	1113	Target Neighborhood Hits	72	Shared Neighborhood Hits	48
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

MT2_MOUSE
θ value	θ > 10 (rank : 1249)	NC score	0.084943 (rank : 827)
Query Neighborhood Hits	1113	Target Neighborhood Hits	81	Shared Neighborhood Hits	53
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

MT3_MOUSE
θ value	θ > 10 (rank : 1250)	NC score	0.171200 (rank : 666)
Query Neighborhood Hits	1113	Target Neighborhood Hits	68	Shared Neighborhood Hits	57
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

MUCDL_HUMAN
θ value	θ > 10 (rank : 1251)	NC score	0.053720 (rank : 991)
Query Neighborhood Hits	1113	Target Neighborhood Hits	777	Shared Neighborhood Hits	182
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NETO1_HUMAN
θ value	θ > 10 (rank : 1252)	NC score	0.062133 (rank : 933)
Query Neighborhood Hits	1113	Target Neighborhood Hits	110	Shared Neighborhood Hits	61
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
θ value	θ > 10 (rank : 1253)	NC score	0.061791 (rank : 937)
Query Neighborhood Hits	1113	Target Neighborhood Hits	109	Shared Neighborhood Hits	61
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO2_HUMAN
θ value	θ > 10 (rank : 1254)	NC score	0.059215 (rank : 946)
Query Neighborhood Hits	1113	Target Neighborhood Hits	109	Shared Neighborhood Hits	59
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
θ value	θ > 10 (rank : 1255)	NC score	0.059179 (rank : 948)
Query Neighborhood Hits	1113	Target Neighborhood Hits	113	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NOV_HUMAN
θ value	θ > 10 (rank : 1256)	NC score	0.067515 (rank : 894)
Query Neighborhood Hits	1113	Target Neighborhood Hits	128	Shared Neighborhood Hits	70
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

NRP1_HUMAN
θ value	θ > 10 (rank : 1257)	NC score	0.062880 (rank : 927)
Query Neighborhood Hits	1113	Target Neighborhood Hits	119	Shared Neighborhood Hits	47
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

NRP1_MOUSE
θ value	θ > 10 (rank : 1258)	NC score	0.062906 (rank : 924)
Query Neighborhood Hits	1113	Target Neighborhood Hits	120	Shared Neighborhood Hits	46
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NRP2_HUMAN
θ value	θ > 10 (rank : 1259)	NC score	0.066864 (rank : 901)
Query Neighborhood Hits	1113	Target Neighborhood Hits	120	Shared Neighborhood Hits	46
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_MOUSE
θ value	θ > 10 (rank : 1260)	NC score	0.064176 (rank : 913)
Query Neighborhood Hits	1113	Target Neighborhood Hits	113	Shared Neighborhood Hits	43
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRX1B_HUMAN
θ value	θ > 10 (rank : 1261)	NC score	0.051869 (rank : 1006)
Query Neighborhood Hits	1113	Target Neighborhood Hits	37	Shared Neighborhood Hits	26
SwissProt Accessions	P58400	Gene names	NRXN1
Domain Architecture	No domain graphic available
Description	Neurexin-1-beta precursor (Neurexin I-beta).

NUD12_HUMAN
θ value	θ > 10 (rank : 1262)	NC score	0.227142 (rank : 583)
Query Neighborhood Hits	1113	Target Neighborhood Hits	222	Shared Neighborhood Hits	193
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

NUD12_MOUSE
θ value	θ > 10 (rank : 1263)	NC score	0.248129 (rank : 559)
Query Neighborhood Hits	1113	Target Neighborhood Hits	243	Shared Neighborhood Hits	215
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

ODFP_MOUSE
θ value	θ > 10 (rank : 1264)	NC score	0.065745 (rank : 905)
Query Neighborhood Hits	1113	Target Neighborhood Hits	75	Shared Neighborhood Hits	44
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

PGCA_MOUSE
θ value	θ > 10 (rank : 1265)	NC score	0.060688 (rank : 941)
Query Neighborhood Hits	1113	Target Neighborhood Hits	643	Shared Neighborhood Hits	85
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

PHXR5_MOUSE
θ value	θ > 10 (rank : 1266)	NC score	0.180269 (rank : 651)
Query Neighborhood Hits	1113	Target Neighborhood Hits	102	Shared Neighborhood Hits	79
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

PROP_HUMAN
θ value	θ > 10 (rank : 1267)	NC score	0.055537 (rank : 976)
Query Neighborhood Hits	1113	Target Neighborhood Hits	126	Shared Neighborhood Hits	50
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

PROP_MOUSE
θ value	θ > 10 (rank : 1268)	NC score	0.071260 (rank : 874)
Query Neighborhood Hits	1113	Target Neighborhood Hits	165	Shared Neighborhood Hits	72
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

RSNL2_HUMAN
θ value	θ > 10 (rank : 1269)	NC score	0.099441 (rank : 794)
Query Neighborhood Hits	1113	Target Neighborhood Hits	136	Shared Neighborhood Hits	110
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

RSNL2_MOUSE
θ value	θ > 10 (rank : 1270)	NC score	0.088955 (rank : 817)
Query Neighborhood Hits	1113	Target Neighborhood Hits	129	Shared Neighborhood Hits	97
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

RSPO1_HUMAN
θ value	θ > 10 (rank : 1271)	NC score	0.052883 (rank : 999)
Query Neighborhood Hits	1113	Target Neighborhood Hits	101	Shared Neighborhood Hits	56
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

RSPO2_HUMAN
θ value	θ > 10 (rank : 1272)	NC score	0.067564 (rank : 893)
Query Neighborhood Hits	1113	Target Neighborhood Hits	90	Shared Neighborhood Hits	53
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

RSPO4_HUMAN
θ value	θ > 10 (rank : 1273)	NC score	0.087548 (rank : 820)
Query Neighborhood Hits	1113	Target Neighborhood Hits	110	Shared Neighborhood Hits	73
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

RSPO4_MOUSE
θ value	θ > 10 (rank : 1274)	NC score	0.077797 (rank : 853)
Query Neighborhood Hits	1113	Target Neighborhood Hits	110	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

SEZ6L_HUMAN
θ value	θ > 10 (rank : 1275)	NC score	0.053688 (rank : 992)
Query Neighborhood Hits	1113	Target Neighborhood Hits	289	Shared Neighborhood Hits	109
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

SHBG_HUMAN
θ value	θ > 10 (rank : 1276)	NC score	0.105158 (rank : 784)
Query Neighborhood Hits	1113	Target Neighborhood Hits	45	Shared Neighborhood Hits	35
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

SHBG_MOUSE
θ value	θ > 10 (rank : 1277)	NC score	0.102078 (rank : 790)
Query Neighborhood Hits	1113	Target Neighborhood Hits	50	Shared Neighborhood Hits	40
SwissProt Accessions	P97497	Gene names	Shbg
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP).

SPIT1_HUMAN
θ value	θ > 10 (rank : 1278)	NC score	0.055300 (rank : 979)
Query Neighborhood Hits	1113	Target Neighborhood Hits	100	Shared Neighborhood Hits	46
SwissProt Accessions	O43278, Q7Z7D2	Gene names	SPINT1, HAI1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

SPIT1_MOUSE
θ value	θ > 10 (rank : 1279)	NC score	0.054079 (rank : 987)
Query Neighborhood Hits	1113	Target Neighborhood Hits	96	Shared Neighborhood Hits	44
SwissProt Accessions	Q9R097	Gene names	Spint1, Hai1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

SPR2F_HUMAN
θ value	θ > 10 (rank : 1280)	NC score	0.076248 (rank : 857)
Query Neighborhood Hits	1113	Target Neighborhood Hits	33	Shared Neighborhood Hits	17
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

SPR2G_MOUSE
θ value	θ > 10 (rank : 1281)	NC score	0.093977 (rank : 804)
Query Neighborhood Hits	1113	Target Neighborhood Hits	53	Shared Neighborhood Hits	26
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

THRB_HUMAN
θ value	θ > 10 (rank : 1282)	NC score	0.056054 (rank : 969)
Query Neighborhood Hits	1113	Target Neighborhood Hits	196	Shared Neighborhood Hits	43
SwissProt Accessions	P00734	Gene names	F2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

THRB_MOUSE
θ value	θ > 10 (rank : 1283)	NC score	0.054620 (rank : 982)
Query Neighborhood Hits	1113	Target Neighborhood Hits	195	Shared Neighborhood Hits	43
SwissProt Accessions	P19221	Gene names	F2, Cf2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

TMG1_HUMAN
θ value	θ > 10 (rank : 1284)	NC score	0.074315 (rank : 864)
Query Neighborhood Hits	1113	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	O14668	Gene names	PRRG1, PRGP1, TMG1
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 1 precursor (Proline- rich Gla protein 1) (Proline-rich gamma-carboxyglutamic acid protein 1).

TMG2_HUMAN
θ value	θ > 10 (rank : 1285)	NC score	0.057697 (rank : 955)
Query Neighborhood Hits	1113	Target Neighborhood Hits	25	Shared Neighborhood Hits	14
SwissProt Accessions	O14669	Gene names	PRRG2, PRGP2, TMG2
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 2 precursor (Proline- rich Gla protein 2) (Proline-rich gamma-carboxyglutamic acid protein 2).

TMG2_MOUSE
θ value	θ > 10 (rank : 1286)	NC score	0.055618 (rank : 974)
Query Neighborhood Hits	1113	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R182, Q9EQI2	Gene names	Prrg2, N4wbp1
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 2 precursor (Proline- rich Gla protein 2) (Proline-rich gamma-carboxyglutamic acid protein 2) (NEDD4 WW domain-binding protein 1).

TMG3_HUMAN
θ value	θ > 10 (rank : 1287)	NC score	0.067058 (rank : 899)
Query Neighborhood Hits	1113	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BZD7, Q8N2N6	Gene names	PRRG3, TMG3
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 3 precursor (Proline- rich Gla protein 3) (Proline-rich gamma-carboxyglutamic acid protein 3).

TMG3_MOUSE
θ value	θ > 10 (rank : 1288)	NC score	0.066478 (rank : 902)
Query Neighborhood Hits	1113	Target Neighborhood Hits	30	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PAQ9	Gene names	Prrg3, Gm368, Tmg3
Domain Architecture	No domain graphic available
Description	Transmembrane gamma-carboxyglutamic acid protein 3 precursor (Proline- rich Gla protein 3) (Proline-rich gamma-carboxyglutamic acid protein 3).

TMG4_HUMAN
θ value	θ > 10 (rank : 1289)	NC score	0.057997 (rank : 954)
Query Neighborhood Hits	1113	Target Neighborhood Hits	31	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BZD6	Gene names	PRRG4, TMG4
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline- rich Gla protein 4) (Proline-rich gamma-carboxyglutamic acid protein 4).

TMG4_MOUSE
θ value	θ > 10 (rank : 1290)	NC score	0.050946 (rank : 1017)
Query Neighborhood Hits	1113	Target Neighborhood Hits	24	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BGN6, Q8BM25	Gene names	Prrg4, Tmg4
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline- rich Gla protein 4) (Proline-rich gamma-carboxyglutamic acid protein 4).

TMPS2_MOUSE
θ value	θ > 10 (rank : 1291)	NC score	0.052888 (rank : 998)
Query Neighborhood Hits	1113	Target Neighborhood Hits	243	Shared Neighborhood Hits	78
SwissProt Accessions	Q9JIQ8, Q9JKC4, Q9QY82	Gene names	Tmprss2
Domain Architecture
Description	Transmembrane protease, serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS3_HUMAN
θ value	θ > 10 (rank : 1292)	NC score	0.050744 (rank : 1021)
Query Neighborhood Hits	1113	Target Neighborhood Hits	245	Shared Neighborhood Hits	70
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

TMPS3_MOUSE
θ value	θ > 10 (rank : 1293)	NC score	0.051539 (rank : 1011)
Query Neighborhood Hits	1113	Target Neighborhood Hits	239	Shared Neighborhood Hits	72
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

TMPS7_HUMAN
θ value	θ > 10 (rank : 1294)	NC score	0.082167 (rank : 838)
Query Neighborhood Hits	1113	Target Neighborhood Hits	275	Shared Neighborhood Hits	103
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS7_MOUSE
θ value	θ > 10 (rank : 1295)	NC score	0.081546 (rank : 840)
Query Neighborhood Hits	1113	Target Neighborhood Hits	275	Shared Neighborhood Hits	100
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS9_HUMAN
θ value	θ > 10 (rank : 1296)	NC score	0.055503 (rank : 977)
Query Neighborhood Hits	1113	Target Neighborhood Hits	276	Shared Neighborhood Hits	84
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

TMPS9_MOUSE
θ value	θ > 10 (rank : 1297)	NC score	0.055396 (rank : 978)
Query Neighborhood Hits	1113	Target Neighborhood Hits	296	Shared Neighborhood Hits	94
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

TNR11_HUMAN
θ value	θ > 10 (rank : 1298)	NC score	0.082814 (rank : 834)
Query Neighborhood Hits	1113	Target Neighborhood Hits	135	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR11_MOUSE
θ value	θ > 10 (rank : 1299)	NC score	0.064176 (rank : 914)
Query Neighborhood Hits	1113	Target Neighborhood Hits	121	Shared Neighborhood Hits	63
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR14_HUMAN
θ value	θ > 10 (rank : 1300)	NC score	0.099555 (rank : 793)
Query Neighborhood Hits	1113	Target Neighborhood Hits	149	Shared Neighborhood Hits	81
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TNR16_HUMAN
θ value	θ > 10 (rank : 1301)	NC score	0.134130 (rank : 749)
Query Neighborhood Hits	1113	Target Neighborhood Hits	183	Shared Neighborhood Hits	110
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR16_MOUSE
θ value	θ > 10 (rank : 1302)	NC score	0.124562 (rank : 763)
Query Neighborhood Hits	1113	Target Neighborhood Hits	178	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR18_HUMAN
θ value	θ > 10 (rank : 1303)	NC score	0.051262 (rank : 1012)
Query Neighborhood Hits	1113	Target Neighborhood Hits	55	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TNR1A_HUMAN
θ value	θ > 10 (rank : 1304)	NC score	0.052528 (rank : 1002)
Query Neighborhood Hits	1113	Target Neighborhood Hits	121	Shared Neighborhood Hits	52
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TNR22_MOUSE
θ value	θ > 10 (rank : 1305)	NC score	0.061903 (rank : 935)
Query Neighborhood Hits	1113	Target Neighborhood Hits	97	Shared Neighborhood Hits	50
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR23_MOUSE
θ value	θ > 10 (rank : 1306)	NC score	0.072378 (rank : 868)
Query Neighborhood Hits	1113	Target Neighborhood Hits	114	Shared Neighborhood Hits	67
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TNR26_MOUSE
θ value	θ > 10 (rank : 1307)	NC score	0.068783 (rank : 886)
Query Neighborhood Hits	1113	Target Neighborhood Hits	106	Shared Neighborhood Hits	64
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR3_MOUSE
θ value	θ > 10 (rank : 1308)	NC score	0.055170 (rank : 981)
Query Neighborhood Hits	1113	Target Neighborhood Hits	113	Shared Neighborhood Hits	61
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR4_HUMAN
θ value	θ > 10 (rank : 1309)	NC score	0.090373 (rank : 812)
Query Neighborhood Hits	1113	Target Neighborhood Hits	152	Shared Neighborhood Hits	85
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR4_MOUSE
θ value	θ > 10 (rank : 1310)	NC score	0.097550 (rank : 799)
Query Neighborhood Hits	1113	Target Neighborhood Hits	137	Shared Neighborhood Hits	74
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TNR5_HUMAN
θ value	θ > 10 (rank : 1311)	NC score	0.051811 (rank : 1007)
Query Neighborhood Hits	1113	Target Neighborhood Hits	102	Shared Neighborhood Hits	53
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TNR6B_HUMAN
θ value	θ > 10 (rank : 1312)	NC score	0.055945 (rank : 971)
Query Neighborhood Hits	1113	Target Neighborhood Hits	103	Shared Neighborhood Hits	48
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TNR6_MOUSE
θ value	θ > 10 (rank : 1313)	NC score	0.055915 (rank : 972)
Query Neighborhood Hits	1113	Target Neighborhood Hits	99	Shared Neighborhood Hits	53
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR7_HUMAN
θ value	θ > 10 (rank : 1314)	NC score	0.091594 (rank : 810)
Query Neighborhood Hits	1113	Target Neighborhood Hits	120	Shared Neighborhood Hits	72
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TNR7_MOUSE
θ value	θ > 10 (rank : 1315)	NC score	0.062000 (rank : 934)
Query Neighborhood Hits	1113	Target Neighborhood Hits	112	Shared Neighborhood Hits	59
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

TNR8_HUMAN
θ value	θ > 10 (rank : 1316)	NC score	0.081629 (rank : 839)
Query Neighborhood Hits	1113	Target Neighborhood Hits	198	Shared Neighborhood Hits	99
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TNR8_MOUSE
θ value	θ > 10 (rank : 1317)	NC score	0.098555 (rank : 797)
Query Neighborhood Hits	1113	Target Neighborhood Hits	208	Shared Neighborhood Hits	99
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TNR9_MOUSE
θ value	θ > 10 (rank : 1318)	NC score	0.077028 (rank : 854)
Query Neighborhood Hits	1113	Target Neighborhood Hits	137	Shared Neighborhood Hits	81
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TRPV2_MOUSE
θ value	θ > 10 (rank : 1319)	NC score	0.084641 (rank : 828)
Query Neighborhood Hits	1113	Target Neighborhood Hits	111	Shared Neighborhood Hits	92
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

TSG6_HUMAN
θ value	θ > 10 (rank : 1320)	NC score	0.083845 (rank : 830)
Query Neighborhood Hits	1113	Target Neighborhood Hits	91	Shared Neighborhood Hits	39
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
θ value	θ > 10 (rank : 1321)	NC score	0.083756 (rank : 832)
Query Neighborhood Hits	1113	Target Neighborhood Hits	91	Shared Neighborhood Hits	38
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

VEGFC_HUMAN
θ value	θ > 10 (rank : 1322)	NC score	0.142466 (rank : 732)
Query Neighborhood Hits	1113	Target Neighborhood Hits	128	Shared Neighborhood Hits	107
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

WFDC3_HUMAN
θ value	θ > 10 (rank : 1323)	NC score	0.161410 (rank : 689)
Query Neighborhood Hits	1113	Target Neighborhood Hits	138	Shared Neighborhood Hits	100
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

WISP1_HUMAN
θ value	θ > 10 (rank : 1324)	NC score	0.057006 (rank : 959)
Query Neighborhood Hits	1113	Target Neighborhood Hits	121	Shared Neighborhood Hits	63
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

WISP1_MOUSE
θ value	θ > 10 (rank : 1325)	NC score	0.056544 (rank : 962)
Query Neighborhood Hits	1113	Target Neighborhood Hits	123	Shared Neighborhood Hits	58
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

WISP2_HUMAN
θ value	θ > 10 (rank : 1326)	NC score	0.072715 (rank : 867)
Query Neighborhood Hits	1113	Target Neighborhood Hits	126	Shared Neighborhood Hits	58
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

WISP2_MOUSE
θ value	θ > 10 (rank : 1327)	NC score	0.060875 (rank : 940)
Query Neighborhood Hits	1113	Target Neighborhood Hits	129	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

ZNFX1_MOUSE
θ value	θ > 10 (rank : 1328)	NC score	0.102747 (rank : 789)
Query Neighborhood Hits	1113	Target Neighborhood Hits	407	Shared Neighborhood Hits	153
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

Hits sorted by NC score

NOTC2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1113	Shared Neighborhood Hits	1113
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
NC score	0.992845 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1069	Shared Neighborhood Hits	917
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC1_HUMAN
NC score	0.984886 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	1113	Target Neighborhood Hits	906	Shared Neighborhood Hits	774
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC3_MOUSE
NC score	0.983610 (rank : 4)	θ value	0 (rank : 6)
Query Neighborhood Hits	1113	Target Neighborhood Hits	975	Shared Neighborhood Hits	790
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_HUMAN
NC score	0.982953 (rank : 5)	θ value	0 (rank : 5)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1062	Shared Neighborhood Hits	816
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC1_MOUSE
NC score	0.980504 (rank : 6)	θ value	0 (rank : 2)
Query Neighborhood Hits	1113	Target Neighborhood Hits	916	Shared Neighborhood Hits	776
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC4_HUMAN
NC score	0.975976 (rank : 7)	θ value	0 (rank : 7)
Query Neighborhood Hits	1113	Target Neighborhood Hits	905	Shared Neighborhood Hits	778
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC4_MOUSE
NC score	0.974904 (rank : 8)	θ value	0 (rank : 8)
Query Neighborhood Hits	1113	Target Neighborhood Hits	872	Shared Neighborhood Hits	755
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

JAG1_HUMAN
NC score	0.874016 (rank : 9)	θ value	3.06238e-149 (rank : 9)
Query Neighborhood Hits	1113	Target Neighborhood Hits	514	Shared Neighborhood Hits	447
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
NC score	0.873939 (rank : 10)	θ value	1.51984e-148 (rank : 10)
Query Neighborhood Hits	1113	Target Neighborhood Hits	518	Shared Neighborhood Hits	446
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG2_HUMAN
NC score	0.872644 (rank : 11)	θ value	4.57613e-145 (rank : 14)
Query Neighborhood Hits	1113	Target Neighborhood Hits	491	Shared Neighborhood Hits	439
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG2_MOUSE
NC score	0.872406 (rank : 12)	θ value	6.38546e-147 (rank : 12)
Query Neighborhood Hits	1113	Target Neighborhood Hits	504	Shared Neighborhood Hits	439
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

DNER_HUMAN
NC score	0.857171 (rank : 13)	θ value	1.10959e-82 (rank : 22)
Query Neighborhood Hits	1113	Target Neighborhood Hits	460	Shared Neighborhood Hits	418
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

CRUM2_HUMAN
NC score	0.857024 (rank : 14)	θ value	4.49445e-92 (rank : 21)
Query Neighborhood Hits	1113	Target Neighborhood Hits	453	Shared Neighborhood Hits	416
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

CRUM1_MOUSE
NC score	0.855426 (rank : 15)	θ value	7.39111e-103 (rank : 19)
Query Neighborhood Hits	1113	Target Neighborhood Hits	444	Shared Neighborhood Hits	411
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CRUM1_HUMAN
NC score	0.854870 (rank : 16)	θ value	5.11853e-104 (rank : 18)
Query Neighborhood Hits	1113	Target Neighborhood Hits	457	Shared Neighborhood Hits	419
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

DNER_MOUSE
NC score	0.854777 (rank : 17)	θ value	1.49966e-79 (rank : 23)
Query Neighborhood Hits	1113	Target Neighborhood Hits	413	Shared Neighborhood Hits	391
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

DLL1_MOUSE
NC score	0.853059 (rank : 18)	θ value	1.15091e-71 (rank : 25)
Query Neighborhood Hits	1113	Target Neighborhood Hits	456	Shared Neighborhood Hits	428
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

DLL1_HUMAN
NC score	0.850050 (rank : 19)	θ value	2.31901e-72 (rank : 24)
Query Neighborhood Hits	1113	Target Neighborhood Hits	455	Shared Neighborhood Hits	417
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DLL4_MOUSE
NC score	0.845949 (rank : 20)	θ value	1.15091e-71 (rank : 26)
Query Neighborhood Hits	1113	Target Neighborhood Hits	440	Shared Neighborhood Hits	404
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL4_HUMAN
NC score	0.845238 (rank : 21)	θ value	1.5555e-68 (rank : 29)
Query Neighborhood Hits	1113	Target Neighborhood Hits	435	Shared Neighborhood Hits	399
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

EGFL9_HUMAN
NC score	0.834871 (rank : 22)	θ value	7.01481e-53 (rank : 47)
Query Neighborhood Hits	1113	Target Neighborhood Hits	365	Shared Neighborhood Hits	351
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
NC score	0.834171 (rank : 23)	θ value	1.08223e-53 (rank : 45)
Query Neighborhood Hits	1113	Target Neighborhood Hits	379	Shared Neighborhood Hits	360
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

DLK_HUMAN
NC score	0.833368 (rank : 24)	θ value	9.50281e-42 (rank : 53)
Query Neighborhood Hits	1113	Target Neighborhood Hits	401	Shared Neighborhood Hits	378
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLL3_MOUSE
NC score	0.831651 (rank : 25)	θ value	1.23823e-49 (rank : 50)
Query Neighborhood Hits	1113	Target Neighborhood Hits	399	Shared Neighborhood Hits	366
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

DLK_MOUSE
NC score	0.831647 (rank : 26)	θ value	6.81017e-40 (rank : 55)
Query Neighborhood Hits	1113	Target Neighborhood Hits	374	Shared Neighborhood Hits	361
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

DLL3_HUMAN
NC score	0.831443 (rank : 27)	θ value	3.60269e-49 (rank : 51)
Query Neighborhood Hits	1113	Target Neighborhood Hits	419	Shared Neighborhood Hits	379
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

MEGF6_HUMAN
NC score	0.827389 (rank : 28)	θ value	3.1125e-93 (rank : 20)
Query Neighborhood Hits	1113	Target Neighborhood Hits	671	Shared Neighborhood Hits	487
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

FBN3_HUMAN
NC score	0.820949 (rank : 29)	θ value	8.93083e-141 (rank : 16)
Query Neighborhood Hits	1113	Target Neighborhood Hits	543	Shared Neighborhood Hits	430
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FBN2_HUMAN
NC score	0.820654 (rank : 30)	θ value	1.42583e-138 (rank : 17)
Query Neighborhood Hits	1113	Target Neighborhood Hits	560	Shared Neighborhood Hits	450
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
NC score	0.820471 (rank : 31)	θ value	3.62588e-142 (rank : 15)
Query Neighborhood Hits	1113	Target Neighborhood Hits	549	Shared Neighborhood Hits	447
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN1_MOUSE
NC score	0.820292 (rank : 32)	θ value	1.57279e-145 (rank : 13)
Query Neighborhood Hits	1113	Target Neighborhood Hits	563	Shared Neighborhood Hits	455
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_HUMAN
NC score	0.819209 (rank : 33)	θ value	2.19465e-147 (rank : 11)
Query Neighborhood Hits	1113	Target Neighborhood Hits	557	Shared Neighborhood Hits	447
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

LTBP4_MOUSE
NC score	0.815568 (rank : 34)	θ value	1.5555e-68 (rank : 30)
Query Neighborhood Hits	1113	Target Neighborhood Hits	607	Shared Neighborhood Hits	416
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

LTBP2_MOUSE
NC score	0.801998 (rank : 35)	θ value	7.45998e-71 (rank : 27)
Query Neighborhood Hits	1113	Target Neighborhood Hits	617	Shared Neighborhood Hits	444
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP2_HUMAN
NC score	0.801842 (rank : 36)	θ value	4.83544e-70 (rank : 28)
Query Neighborhood Hits	1113	Target Neighborhood Hits	552	Shared Neighborhood Hits	425
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP3_HUMAN
NC score	0.792924 (rank : 37)	θ value	3.974e-56 (rank : 39)
Query Neighborhood Hits	1113	Target Neighborhood Hits	502	Shared Neighborhood Hits	400
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP3_MOUSE
NC score	0.788453 (rank : 38)	θ value	2.041e-52 (rank : 48)
Query Neighborhood Hits	1113	Target Neighborhood Hits	475	Shared Neighborhood Hits	396
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTB1L_HUMAN
NC score	0.780966 (rank : 39)	θ value	1.07972e-61 (rank : 32)
Query Neighborhood Hits	1113	Target Neighborhood Hits	553	Shared Neighborhood Hits	427
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_MOUSE
NC score	0.780617 (rank : 40)	θ value	1.41016e-61 (rank : 34)
Query Neighborhood Hits	1113	Target Neighborhood Hits	514	Shared Neighborhood Hits	424
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
NC score	0.779810 (rank : 41)	θ value	1.41016e-61 (rank : 35)
Query Neighborhood Hits	1113	Target Neighborhood Hits	479	Shared Neighborhood Hits	400
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
NC score	0.779691 (rank : 42)	θ value	1.07972e-61 (rank : 33)
Query Neighborhood Hits	1113	Target Neighborhood Hits	502	Shared Neighborhood Hits	408
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

NELL1_HUMAN
NC score	0.777825 (rank : 43)	θ value	1.85889e-29 (rank : 65)
Query Neighborhood Hits	1113	Target Neighborhood Hits	451	Shared Neighborhood Hits	384
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NELL2_HUMAN
NC score	0.776499 (rank : 44)	θ value	3.86705e-35 (rank : 57)
Query Neighborhood Hits	1113	Target Neighborhood Hits	449	Shared Neighborhood Hits	387
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
NC score	0.775525 (rank : 45)	θ value	1.46948e-34 (rank : 59)
Query Neighborhood Hits	1113	Target Neighborhood Hits	436	Shared Neighborhood Hits	383
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

WIF1_HUMAN
NC score	0.766180 (rank : 46)	θ value	9.24701e-21 (rank : 109)
Query Neighborhood Hits	1113	Target Neighborhood Hits	392	Shared Neighborhood Hits	363
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_MOUSE
NC score	0.763931 (rank : 47)	θ value	1.42661e-21 (rank : 101)
Query Neighborhood Hits	1113	Target Neighborhood Hits	393	Shared Neighborhood Hits	361
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

FBLN2_HUMAN
NC score	0.755665 (rank : 48)	θ value	5.7518e-47 (rank : 52)
Query Neighborhood Hits	1113	Target Neighborhood Hits	392	Shared Neighborhood Hits	310
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_MOUSE
NC score	0.751159 (rank : 49)	θ value	3.05695e-40 (rank : 54)
Query Neighborhood Hits	1113	Target Neighborhood Hits	505	Shared Neighborhood Hits	350
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

SREC_HUMAN
NC score	0.746791 (rank : 50)	θ value	5.77852e-31 (rank : 62)
Query Neighborhood Hits	1113	Target Neighborhood Hits	645	Shared Neighborhood Hits	431
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

FBLN1_HUMAN
NC score	0.741085 (rank : 51)	θ value	6.37413e-38 (rank : 56)
Query Neighborhood Hits	1113	Target Neighborhood Hits	324	Shared Neighborhood Hits	298
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN1_MOUSE
NC score	0.739696 (rank : 52)	θ value	1.46948e-34 (rank : 58)
Query Neighborhood Hits	1113	Target Neighborhood Hits	329	Shared Neighborhood Hits	296
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

SREC2_MOUSE
NC score	0.739056 (rank : 53)	θ value	1.05554e-24 (rank : 81)
Query Neighborhood Hits	1113	Target Neighborhood Hits	605	Shared Neighborhood Hits	421
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

C1QR1_HUMAN
NC score	0.738855 (rank : 54)	θ value	1.29031e-22 (rank : 93)
Query Neighborhood Hits	1113	Target Neighborhood Hits	493	Shared Neighborhood Hits	341
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
NC score	0.737960 (rank : 55)	θ value	1.92365e-26 (rank : 75)
Query Neighborhood Hits	1113	Target Neighborhood Hits	342	Shared Neighborhood Hits	298
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

SREC2_HUMAN
NC score	0.730847 (rank : 56)	θ value	1.05554e-24 (rank : 80)
Query Neighborhood Hits	1113	Target Neighborhood Hits	645	Shared Neighborhood Hits	421
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SCUB3_HUMAN
NC score	0.727245 (rank : 57)	θ value	2.86786e-30 (rank : 64)
Query Neighborhood Hits	1113	Target Neighborhood Hits	428	Shared Neighborhood Hits	307
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
NC score	0.726660 (rank : 58)	θ value	2.19584e-30 (rank : 63)
Query Neighborhood Hits	1113	Target Neighborhood Hits	442	Shared Neighborhood Hits	314
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

GAS6_MOUSE
NC score	0.719496 (rank : 59)	θ value	8.36355e-22 (rank : 99)
Query Neighborhood Hits	1113	Target Neighborhood Hits	343	Shared Neighborhood Hits	314
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

FBLN4_HUMAN
NC score	0.718618 (rank : 60)	θ value	1.33217e-27 (rank : 69)
Query Neighborhood Hits	1113	Target Neighborhood Hits	278	Shared Neighborhood Hits	254
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

STAB2_HUMAN
NC score	0.718107 (rank : 61)	θ value	2.87452e-22 (rank : 95)
Query Neighborhood Hits	1113	Target Neighborhood Hits	534	Shared Neighborhood Hits	412
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

GAS6_HUMAN
NC score	0.716699 (rank : 62)	θ value	5.99374e-20 (rank : 115)
Query Neighborhood Hits	1113	Target Neighborhood Hits	348	Shared Neighborhood Hits	309
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

FBLN5_HUMAN
NC score	0.715065 (rank : 63)	θ value	9.54697e-26 (rank : 78)
Query Neighborhood Hits	1113	Target Neighborhood Hits	329	Shared Neighborhood Hits	293
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

PROS_HUMAN
NC score	0.715023 (rank : 64)	θ value	7.82807e-20 (rank : 118)
Query Neighborhood Hits	1113	Target Neighborhood Hits	340	Shared Neighborhood Hits	318
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

STAB2_MOUSE
NC score	0.713282 (rank : 65)	θ value	8.36355e-22 (rank : 100)
Query Neighborhood Hits	1113	Target Neighborhood Hits	528	Shared Neighborhood Hits	410
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

STAB1_HUMAN
NC score	0.713010 (rank : 66)	θ value	7.56453e-23 (rank : 92)
Query Neighborhood Hits	1113	Target Neighborhood Hits	546	Shared Neighborhood Hits	421
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB1_MOUSE
NC score	0.712165 (rank : 67)	θ value	2.27762e-19 (rank : 120)
Query Neighborhood Hits	1113	Target Neighborhood Hits	566	Shared Neighborhood Hits	433
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

TRBM_HUMAN
NC score	0.712133 (rank : 68)	θ value	5.07402e-19 (rank : 124)
Query Neighborhood Hits	1113	Target Neighborhood Hits	339	Shared Neighborhood Hits	285
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

FBLN4_MOUSE
NC score	0.711945 (rank : 69)	θ value	1.47289e-26 (rank : 74)
Query Neighborhood Hits	1113	Target Neighborhood Hits	270	Shared Neighborhood Hits	248
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_MOUSE
NC score	0.711279 (rank : 70)	θ value	2.27234e-27 (rank : 70)
Query Neighborhood Hits	1113	Target Neighborhood Hits	317	Shared Neighborhood Hits	278
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

PROS_MOUSE
NC score	0.710686 (rank : 71)	θ value	6.62687e-19 (rank : 127)
Query Neighborhood Hits	1113	Target Neighborhood Hits	330	Shared Neighborhood Hits	308
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

FBLN3_HUMAN
NC score	0.709014 (rank : 72)	θ value	5.23862e-24 (rank : 85)
Query Neighborhood Hits	1113	Target Neighborhood Hits	293	Shared Neighborhood Hits	272
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN3_MOUSE
NC score	0.702124 (rank : 73)	θ value	1.16704e-23 (rank : 87)
Query Neighborhood Hits	1113	Target Neighborhood Hits	279	Shared Neighborhood Hits	260
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

CUBN_MOUSE
NC score	0.700379 (rank : 74)	θ value	2.25659e-51 (rank : 49)
Query Neighborhood Hits	1113	Target Neighborhood Hits	477	Shared Neighborhood Hits	376
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

TRBM_MOUSE
NC score	0.698067 (rank : 75)	θ value	5.25075e-16 (rank : 151)
Query Neighborhood Hits	1113	Target Neighborhood Hits	361	Shared Neighborhood Hits	290
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

CUBN_HUMAN
NC score	0.695930 (rank : 76)	θ value	1.41344e-53 (rank : 46)
Query Neighborhood Hits	1113	Target Neighborhood Hits	482	Shared Neighborhood Hits	387
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

EGFL7_HUMAN
NC score	0.690190 (rank : 77)	θ value	5.26297e-08 (rank : 338)
Query Neighborhood Hits	1113	Target Neighborhood Hits	325	Shared Neighborhood Hits	301
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

CREL1_HUMAN
NC score	0.685190 (rank : 78)	θ value	7.34386e-10 (rank : 268)
Query Neighborhood Hits	1113	Target Neighborhood Hits	441	Shared Neighborhood Hits	285
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

EGFL7_MOUSE
NC score	0.680747 (rank : 79)	θ value	4.45536e-07 (rank : 373)
Query Neighborhood Hits	1113	Target Neighborhood Hits	287	Shared Neighborhood Hits	272
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

CREL1_MOUSE
NC score	0.672924 (rank : 80)	θ value	2.13673e-09 (rank : 282)
Query Neighborhood Hits	1113	Target Neighborhood Hits	524	Shared Neighborhood Hits	296
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

EGFL8_MOUSE
NC score	0.672712 (rank : 81)	θ value	3.64472e-09 (rank : 292)
Query Neighborhood Hits	1113	Target Neighborhood Hits	266	Shared Neighborhood Hits	259
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EGFL8_HUMAN
NC score	0.668473 (rank : 82)	θ value	4.76016e-09 (rank : 296)
Query Neighborhood Hits	1113	Target Neighborhood Hits	270	Shared Neighborhood Hits	254
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

UROM_HUMAN
NC score	0.668100 (rank : 83)	θ value	4.29542e-18 (rank : 136)
Query Neighborhood Hits	1113	Target Neighborhood Hits	284	Shared Neighborhood Hits	258
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

EGF_MOUSE
NC score	0.665676 (rank : 84)	θ value	6.20254e-17 (rank : 145)
Query Neighborhood Hits	1113	Target Neighborhood Hits	358	Shared Neighborhood Hits	326
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

NID2_HUMAN
NC score	0.664433 (rank : 85)	θ value	2.43343e-21 (rank : 105)
Query Neighborhood Hits	1113	Target Neighborhood Hits	456	Shared Neighborhood Hits	325
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID2_MOUSE
NC score	0.662804 (rank : 86)	θ value	7.0802e-21 (rank : 108)
Query Neighborhood Hits	1113	Target Neighborhood Hits	338	Shared Neighborhood Hits	283
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

SUSD1_HUMAN
NC score	0.660551 (rank : 87)	θ value	2.28291e-11 (rank : 228)
Query Neighborhood Hits	1113	Target Neighborhood Hits	285	Shared Neighborhood Hits	234
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

MATN2_HUMAN
NC score	0.657466 (rank : 88)	θ value	1.57365e-28 (rank : 68)
Query Neighborhood Hits	1113	Target Neighborhood Hits	365	Shared Neighborhood Hits	276
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

AGRIN_HUMAN
NC score	0.657185 (rank : 89)	θ value	3.39556e-23 (rank : 90)
Query Neighborhood Hits	1113	Target Neighborhood Hits	582	Shared Neighborhood Hits	408
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

NID1_MOUSE
NC score	0.656437 (rank : 90)	θ value	5.99374e-20 (rank : 117)
Query Neighborhood Hits	1113	Target Neighborhood Hits	335	Shared Neighborhood Hits	277
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

UROM_MOUSE
NC score	0.656194 (rank : 91)	θ value	1.63225e-17 (rank : 140)
Query Neighborhood Hits	1113	Target Neighborhood Hits	276	Shared Neighborhood Hits	253
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

NID1_HUMAN
NC score	0.655253 (rank : 92)	θ value	2.06002e-20 (rank : 112)
Query Neighborhood Hits	1113	Target Neighborhood Hits	329	Shared Neighborhood Hits	284
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

MEGF8_HUMAN
NC score	0.649914 (rank : 93)	θ value	3.89403e-11 (rank : 231)
Query Neighborhood Hits	1113	Target Neighborhood Hits	528	Shared Neighborhood Hits	357
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_MOUSE
NC score	0.646542 (rank : 94)	θ value	3.52202e-12 (rank : 209)
Query Neighborhood Hits	1113	Target Neighborhood Hits	520	Shared Neighborhood Hits	350
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MATN2_MOUSE
NC score	0.645583 (rank : 95)	θ value	2.96777e-27 (rank : 71)
Query Neighborhood Hits	1113	Target Neighborhood Hits	356	Shared Neighborhood Hits	275
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

TSP4_MOUSE
NC score	0.639443 (rank : 96)	θ value	3.28887e-18 (rank : 133)
Query Neighborhood Hits	1113	Target Neighborhood Hits	276	Shared Neighborhood Hits	257
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

LRP1_HUMAN
NC score	0.637417 (rank : 97)	θ value	4.14116e-29 (rank : 66)
Query Neighborhood Hits	1113	Target Neighborhood Hits	617	Shared Neighborhood Hits	460
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

TSP4_HUMAN
NC score	0.636648 (rank : 98)	θ value	6.62687e-19 (rank : 128)
Query Neighborhood Hits	1113	Target Neighborhood Hits	277	Shared Neighborhood Hits	250
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

EDIL3_MOUSE
NC score	0.635539 (rank : 99)	θ value	6.61148e-27 (rank : 73)
Query Neighborhood Hits	1113	Target Neighborhood Hits	317	Shared Neighborhood Hits	290
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

TENA_HUMAN
NC score	0.634630 (rank : 100)	θ value	1.55911e-60 (rank : 36)
Query Neighborhood Hits	1113	Target Neighborhood Hits	631	Shared Neighborhood Hits	401
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

LRP1B_HUMAN
NC score	0.634067 (rank : 101)	θ value	5.06226e-27 (rank : 72)
Query Neighborhood Hits	1113	Target Neighborhood Hits	602	Shared Neighborhood Hits	454
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

EGF_HUMAN
NC score	0.632939 (rank : 102)	θ value	6.41864e-14 (rank : 181)
Query Neighborhood Hits	1113	Target Neighborhood Hits	343	Shared Neighborhood Hits	307
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

TENX_HUMAN
NC score	0.632445 (rank : 103)	θ value	1.90147e-66 (rank : 31)
Query Neighborhood Hits	1113	Target Neighborhood Hits	789	Shared Neighborhood Hits	436
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

LRP1B_MOUSE
NC score	0.630180 (rank : 104)	θ value	7.30988e-26 (rank : 77)
Query Neighborhood Hits	1113	Target Neighborhood Hits	606	Shared Neighborhood Hits	457
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

EMR1_HUMAN
NC score	0.629947 (rank : 105)	θ value	1.62847e-25 (rank : 79)
Query Neighborhood Hits	1113	Target Neighborhood Hits	382	Shared Neighborhood Hits	282
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

TENA_MOUSE
NC score	0.629041 (rank : 106)	θ value	2.48917e-58 (rank : 37)
Query Neighborhood Hits	1113	Target Neighborhood Hits	596	Shared Neighborhood Hits	390
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

EDIL3_HUMAN
NC score	0.626378 (rank : 107)	θ value	7.30988e-26 (rank : 76)
Query Neighborhood Hits	1113	Target Neighborhood Hits	292	Shared Neighborhood Hits	265
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

COMP_MOUSE
NC score	0.617748 (rank : 108)	θ value	2.35696e-16 (rank : 147)
Query Neighborhood Hits	1113	Target Neighborhood Hits	290	Shared Neighborhood Hits	252
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

SLIT1_MOUSE
NC score	0.611357 (rank : 109)	θ value	1.51013e-55 (rank : 41)
Query Neighborhood Hits	1113	Target Neighborhood Hits	715	Shared Neighborhood Hits	395
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

SLIT1_HUMAN
NC score	0.609739 (rank : 110)	θ value	2.32979e-56 (rank : 38)
Query Neighborhood Hits	1113	Target Neighborhood Hits	700	Shared Neighborhood Hits	390
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

KRA53_HUMAN
NC score	0.609166 (rank : 111)	θ value	8.40245e-06 (rank : 434)
Query Neighborhood Hits	1113	Target Neighborhood Hits	331	Shared Neighborhood Hits	269
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

EMR2_HUMAN
NC score	0.606095 (rank : 112)	θ value	5.79196e-23 (rank : 91)
Query Neighborhood Hits	1113	Target Neighborhood Hits	345	Shared Neighborhood Hits	264
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

KRA51_HUMAN
NC score	0.603987 (rank : 113)	θ value	0.00175202 (rank : 530)
Query Neighborhood Hits	1113	Target Neighborhood Hits	288	Shared Neighborhood Hits	227
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

SLIT2_HUMAN
NC score	0.602428 (rank : 114)	θ value	3.974e-56 (rank : 40)
Query Neighborhood Hits	1113	Target Neighborhood Hits	708	Shared Neighborhood Hits	400
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

ZAN_MOUSE
NC score	0.602169 (rank : 115)	θ value	3.07116e-24 (rank : 83)
Query Neighborhood Hits	1113	Target Neighborhood Hits	808	Shared Neighborhood Hits	460
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

EMR1_MOUSE
NC score	0.600493 (rank : 116)	θ value	9.2256e-29 (rank : 67)
Query Neighborhood Hits	1113	Target Neighborhood Hits	349	Shared Neighborhood Hits	262
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

CD97_HUMAN
NC score	0.597423 (rank : 117)	θ value	2.59989e-23 (rank : 89)
Query Neighborhood Hits	1113	Target Neighborhood Hits	353	Shared Neighborhood Hits	266
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

SLIT2_MOUSE
NC score	0.597301 (rank : 118)	θ value	1.51013e-55 (rank : 42)
Query Neighborhood Hits	1113	Target Neighborhood Hits	684	Shared Neighborhood Hits	379
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

COMP_HUMAN
NC score	0.595565 (rank : 119)	θ value	4.16044e-13 (rank : 191)
Query Neighborhood Hits	1113	Target Neighborhood Hits	258	Shared Neighborhood Hits	234
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

SLIT3_MOUSE
NC score	0.589210 (rank : 120)	θ value	2.57589e-55 (rank : 44)
Query Neighborhood Hits	1113	Target Neighborhood Hits	700	Shared Neighborhood Hits	390
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

LAMA5_MOUSE
NC score	0.587598 (rank : 121)	θ value	1.16704e-23 (rank : 88)
Query Neighborhood Hits	1113	Target Neighborhood Hits	828	Shared Neighborhood Hits	390
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

KR107_HUMAN
NC score	0.584571 (rank : 122)	θ value	1.47974e-10 (rank : 253)
Query Neighborhood Hits	1113	Target Neighborhood Hits	330	Shared Neighborhood Hits	266
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KRA58_HUMAN
NC score	0.582612 (rank : 123)	θ value	2.44474e-05 (rank : 451)
Query Neighborhood Hits	1113	Target Neighborhood Hits	324	Shared Neighborhood Hits	256
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

SLIT3_HUMAN
NC score	0.582337 (rank : 124)	θ value	2.57589e-55 (rank : 43)
Query Neighborhood Hits	1113	Target Neighborhood Hits	682	Shared Neighborhood Hits	373
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

KR106_HUMAN
NC score	0.582050 (rank : 125)	θ value	2.13673e-09 (rank : 285)
Query Neighborhood Hits	1113	Target Neighborhood Hits	347	Shared Neighborhood Hits	275
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

TSP3_MOUSE
NC score	0.580586 (rank : 126)	θ value	4.44505e-15 (rank : 159)
Query Neighborhood Hits	1113	Target Neighborhood Hits	247	Shared Neighborhood Hits	223
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

KR104_HUMAN
NC score	0.579151 (rank : 127)	θ value	9.59137e-10 (rank : 273)
Query Neighborhood Hits	1113	Target Neighborhood Hits	313	Shared Neighborhood Hits	252
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

LAMA5_HUMAN
NC score	0.578232 (rank : 128)	θ value	1.37858e-24 (rank : 82)
Query Neighborhood Hits	1113	Target Neighborhood Hits	976	Shared Neighborhood Hits	436
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

TSP3_HUMAN
NC score	0.572381 (rank : 129)	θ value	1.29331e-14 (rank : 170)
Query Neighborhood Hits	1113	Target Neighborhood Hits	250	Shared Neighborhood Hits	219
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

NAGPA_HUMAN
NC score	0.570839 (rank : 130)	θ value	4.0297e-08 (rank : 336)
Query Neighborhood Hits	1113	Target Neighborhood Hits	282	Shared Neighborhood Hits	263
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

MEGF9_HUMAN
NC score	0.569790 (rank : 131)	θ value	1.06045e-08 (rank : 310)
Query Neighborhood Hits	1113	Target Neighborhood Hits	557	Shared Neighborhood Hits	330
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

NAGPA_MOUSE
NC score	0.565621 (rank : 132)	θ value	6.87365e-08 (rank : 340)
Query Neighborhood Hits	1113	Target Neighborhood Hits	308	Shared Neighborhood Hits	290
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

LAMB2_HUMAN
NC score	0.558537 (rank : 133)	θ value	2.43343e-21 (rank : 104)
Query Neighborhood Hits	1113	Target Neighborhood Hits	692	Shared Neighborhood Hits	327
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LRP2_HUMAN
NC score	0.558354 (rank : 134)	θ value	1.29331e-14 (rank : 168)
Query Neighborhood Hits	1113	Target Neighborhood Hits	573	Shared Neighborhood Hits	436
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

CD248_MOUSE
NC score	0.558181 (rank : 135)	θ value	2.61198e-07 (rank : 361)
Query Neighborhood Hits	1113	Target Neighborhood Hits	578	Shared Neighborhood Hits	344
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD248_HUMAN
NC score	0.558095 (rank : 136)	θ value	8.97725e-08 (rank : 344)
Query Neighborhood Hits	1113	Target Neighborhood Hits	679	Shared Neighborhood Hits	376
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

LAMA1_MOUSE
NC score	0.553790 (rank : 137)	θ value	5.99374e-20 (rank : 116)
Query Neighborhood Hits	1113	Target Neighborhood Hits	838	Shared Neighborhood Hits	364
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMB2_MOUSE
NC score	0.552050 (rank : 138)	θ value	1.13037e-18 (rank : 130)
Query Neighborhood Hits	1113	Target Neighborhood Hits	722	Shared Neighborhood Hits	322
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMA1_HUMAN
NC score	0.551390 (rank : 139)	θ value	2.43343e-21 (rank : 103)
Query Neighborhood Hits	1113	Target Neighborhood Hits	804	Shared Neighborhood Hits	355
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LDLR_HUMAN
NC score	0.549911 (rank : 140)	θ value	4.91457e-14 (rank : 177)
Query Neighborhood Hits	1113	Target Neighborhood Hits	375	Shared Neighborhood Hits	317
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LAMC3_MOUSE
NC score	0.546616 (rank : 141)	θ value	5.42112e-21 (rank : 106)
Query Neighborhood Hits	1113	Target Neighborhood Hits	624	Shared Neighborhood Hits	322
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

MEGF9_MOUSE
NC score	0.543974 (rank : 142)	θ value	1.38499e-08 (rank : 315)
Query Neighborhood Hits	1113	Target Neighborhood Hits	896	Shared Neighborhood Hits	402
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

VLDLR_HUMAN
NC score	0.542620 (rank : 143)	θ value	2.60593e-15 (rank : 157)
Query Neighborhood Hits	1113	Target Neighborhood Hits	383	Shared Neighborhood Hits	307
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
NC score	0.540680 (rank : 144)	θ value	7.58209e-15 (rank : 162)
Query Neighborhood Hits	1113	Target Neighborhood Hits	360	Shared Neighborhood Hits	295
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

LAMC3_HUMAN
NC score	0.539221 (rank : 145)	θ value	8.65492e-19 (rank : 129)
Query Neighborhood Hits	1113	Target Neighborhood Hits	588	Shared Neighborhood Hits	333
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

HHIP_HUMAN
NC score	0.536959 (rank : 146)	θ value	1.43324e-05 (rank : 441)
Query Neighborhood Hits	1113	Target Neighborhood Hits	249	Shared Neighborhood Hits	240
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

MATN3_MOUSE
NC score	0.536497 (rank : 147)	θ value	5.08577e-11 (rank : 236)
Query Neighborhood Hits	1113	Target Neighborhood Hits	261	Shared Neighborhood Hits	216
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_HUMAN
NC score	0.534057 (rank : 148)	θ value	6.64225e-11 (rank : 240)
Query Neighborhood Hits	1113	Target Neighborhood Hits	268	Shared Neighborhood Hits	213
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

PROZ_MOUSE
NC score	0.533354 (rank : 149)	θ value	8.11959e-09 (rank : 307)
Query Neighborhood Hits	1113	Target Neighborhood Hits	410	Shared Neighborhood Hits	274
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

MATN4_HUMAN
NC score	0.533070 (rank : 150)	θ value	1.99992e-07 (rank : 358)
Query Neighborhood Hits	1113	Target Neighborhood Hits	287	Shared Neighborhood Hits	237
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

LRP8_MOUSE
NC score	0.530407 (rank : 151)	θ value	6.21693e-09 (rank : 303)
Query Neighborhood Hits	1113	Target Neighborhood Hits	385	Shared Neighborhood Hits	303
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

PROZ_HUMAN
NC score	0.529151 (rank : 152)	θ value	3.29651e-10 (rank : 258)
Query Neighborhood Hits	1113	Target Neighborhood Hits	422	Shared Neighborhood Hits	282
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

KRA59_HUMAN
NC score	0.527609 (rank : 153)	θ value	0.000461057 (rank : 501)
Query Neighborhood Hits	1113	Target Neighborhood Hits	310	Shared Neighborhood Hits	236
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

LAMC2_MOUSE
NC score	0.527278 (rank : 154)	θ value	1.33837e-11 (rank : 222)
Query Neighborhood Hits	1113	Target Neighborhood Hits	614	Shared Neighborhood Hits	304
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

KRA57_HUMAN
NC score	0.526984 (rank : 155)	θ value	0.0113563 (rank : 597)
Query Neighborhood Hits	1113	Target Neighborhood Hits	269	Shared Neighborhood Hits	220
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

LDLR_MOUSE
NC score	0.522607 (rank : 156)	θ value	1.133e-10 (rank : 247)
Query Neighborhood Hits	1113	Target Neighborhood Hits	382	Shared Neighborhood Hits	310
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

CD97_MOUSE
NC score	0.518008 (rank : 157)	θ value	2.0648e-12 (rank : 203)
Query Neighborhood Hits	1113	Target Neighborhood Hits	295	Shared Neighborhood Hits	221
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CSPG2_MOUSE
NC score	0.517432 (rank : 158)	θ value	4.01107e-24 (rank : 84)
Query Neighborhood Hits	1113	Target Neighborhood Hits	711	Shared Neighborhood Hits	326
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

LAMB1_MOUSE
NC score	0.516914 (rank : 159)	θ value	6.62687e-19 (rank : 126)
Query Neighborhood Hits	1113	Target Neighborhood Hits	919	Shared Neighborhood Hits	321
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMA2_HUMAN
NC score	0.516627 (rank : 160)	θ value	3.75424e-22 (rank : 97)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1092	Shared Neighborhood Hits	365
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

HHIP_MOUSE
NC score	0.515698 (rank : 161)	θ value	0.000121331 (rank : 474)
Query Neighborhood Hits	1113	Target Neighborhood Hits	219	Shared Neighborhood Hits	211
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

LRP8_HUMAN
NC score	0.513227 (rank : 162)	θ value	1.25267e-09 (rank : 274)
Query Neighborhood Hits	1113	Target Neighborhood Hits	346	Shared Neighborhood Hits	273
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

CSPG2_HUMAN
NC score	0.512798 (rank : 163)	θ value	1.16704e-23 (rank : 86)
Query Neighborhood Hits	1113	Target Neighborhood Hits	681	Shared Neighborhood Hits	317
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

GRN_MOUSE
NC score	0.511991 (rank : 164)	θ value	4.0297e-08 (rank : 335)
Query Neighborhood Hits	1113	Target Neighborhood Hits	248	Shared Neighborhood Hits	212
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

KRA55_HUMAN
NC score	0.511734 (rank : 165)	θ value	0.00390308 (rank : 553)
Query Neighborhood Hits	1113	Target Neighborhood Hits	257	Shared Neighborhood Hits	212
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

CSPG3_MOUSE
NC score	0.508387 (rank : 166)	θ value	3.75424e-22 (rank : 96)
Query Neighborhood Hits	1113	Target Neighborhood Hits	657	Shared Neighborhood Hits	317
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

NTNG2_MOUSE
NC score	0.507927 (rank : 167)	θ value	4.45536e-07 (rank : 374)
Query Neighborhood Hits	1113	Target Neighborhood Hits	276	Shared Neighborhood Hits	257
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

LAMC2_HUMAN
NC score	0.507781 (rank : 168)	θ value	7.84624e-12 (rank : 219)
Query Neighborhood Hits	1113	Target Neighborhood Hits	715	Shared Neighborhood Hits	302
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LAMC1_MOUSE
NC score	0.506590 (rank : 169)	θ value	4.74913e-17 (rank : 143)
Query Neighborhood Hits	1113	Target Neighborhood Hits	856	Shared Neighborhood Hits	322
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

MATN4_MOUSE
NC score	0.505727 (rank : 170)	θ value	9.92553e-07 (rank : 394)
Query Neighborhood Hits	1113	Target Neighborhood Hits	277	Shared Neighborhood Hits	230
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

ELTD1_MOUSE
NC score	0.505634 (rank : 171)	θ value	3.18553e-13 (rank : 188)
Query Neighborhood Hits	1113	Target Neighborhood Hits	288	Shared Neighborhood Hits	215
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

KRA54_HUMAN
NC score	0.504699 (rank : 172)	θ value	0.00869519 (rank : 585)
Query Neighborhood Hits	1113	Target Neighborhood Hits	270	Shared Neighborhood Hits	207
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

CSPG3_HUMAN
NC score	0.502460 (rank : 173)	θ value	7.0802e-21 (rank : 107)
Query Neighborhood Hits	1113	Target Neighborhood Hits	676	Shared Neighborhood Hits	328
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

GRN_HUMAN
NC score	0.502191 (rank : 174)	θ value	2.88788e-06 (rank : 413)
Query Neighborhood Hits	1113	Target Neighborhood Hits	268	Shared Neighborhood Hits	216
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

LAMB1_HUMAN
NC score	0.499936 (rank : 175)	θ value	1.92812e-18 (rank : 132)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1018	Shared Neighborhood Hits	336
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

KR101_HUMAN
NC score	0.496929 (rank : 176)	θ value	2.44474e-05 (rank : 450)
Query Neighborhood Hits	1113	Target Neighborhood Hits	261	Shared Neighborhood Hits	207
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

NTNG2_HUMAN
NC score	0.496633 (rank : 177)	θ value	1.80886e-08 (rank : 324)
Query Neighborhood Hits	1113	Target Neighborhood Hits	276	Shared Neighborhood Hits	252
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

LAMB3_MOUSE
NC score	0.496515 (rank : 178)	θ value	5.08577e-11 (rank : 235)
Query Neighborhood Hits	1113	Target Neighborhood Hits	444	Shared Neighborhood Hits	254
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LAMC1_HUMAN
NC score	0.493061 (rank : 179)	θ value	6.85773e-16 (rank : 152)
Query Neighborhood Hits	1113	Target Neighborhood Hits	922	Shared Neighborhood Hits	330
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMA2_MOUSE
NC score	0.492507 (rank : 180)	θ value	1.5773e-20 (rank : 111)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1198	Shared Neighborhood Hits	379
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

ITB6_MOUSE
NC score	0.492422 (rank : 181)	θ value	1.63604e-09 (rank : 278)
Query Neighborhood Hits	1113	Target Neighborhood Hits	341	Shared Neighborhood Hits	286
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

LRP4_MOUSE
NC score	0.485970 (rank : 182)	θ value	8.11959e-09 (rank : 306)
Query Neighborhood Hits	1113	Target Neighborhood Hits	351	Shared Neighborhood Hits	285
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LRP4_HUMAN
NC score	0.482597 (rank : 183)	θ value	2.13673e-09 (rank : 286)
Query Neighborhood Hits	1113	Target Neighborhood Hits	355	Shared Neighborhood Hits	287
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LAMA3_MOUSE
NC score	0.479479 (rank : 184)	θ value	6.64225e-11 (rank : 239)
Query Neighborhood Hits	1113	Target Neighborhood Hits	859	Shared Neighborhood Hits	357
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

ITB6_HUMAN
NC score	0.475739 (rank : 185)	θ value	5.08577e-11 (rank : 234)
Query Neighborhood Hits	1113	Target Neighborhood Hits	318	Shared Neighborhood Hits	272
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB5_MOUSE
NC score	0.473456 (rank : 186)	θ value	1.53129e-07 (rank : 352)
Query Neighborhood Hits	1113	Target Neighborhood Hits	329	Shared Neighborhood Hits	283
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

NTNG1_MOUSE
NC score	0.472382 (rank : 187)	θ value	2.36244e-08 (rank : 326)
Query Neighborhood Hits	1113	Target Neighborhood Hits	246	Shared Neighborhood Hits	217
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

USH2A_MOUSE
NC score	0.472225 (rank : 188)	θ value	1.52774e-15 (rank : 155)
Query Neighborhood Hits	1113	Target Neighborhood Hits	626	Shared Neighborhood Hits	323
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

NTNG1_HUMAN
NC score	0.472047 (rank : 189)	θ value	2.79066e-09 (rank : 290)
Query Neighborhood Hits	1113	Target Neighborhood Hits	247	Shared Neighborhood Hits	215
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

KR171_HUMAN
NC score	0.469459 (rank : 190)	θ value	0.279714 (rank : 743)
Query Neighborhood Hits	1113	Target Neighborhood Hits	144	Shared Neighborhood Hits	125
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KR102_HUMAN
NC score	0.468903 (rank : 191)	θ value	2.21117e-06 (rank : 407)
Query Neighborhood Hits	1113	Target Neighborhood Hits	264	Shared Neighborhood Hits	219
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

CRIM1_HUMAN
NC score	0.465605 (rank : 192)	θ value	2.61198e-07 (rank : 363)
Query Neighborhood Hits	1113	Target Neighborhood Hits	362	Shared Neighborhood Hits	260
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

LAMB3_HUMAN
NC score	0.464222 (rank : 193)	θ value	8.67504e-11 (rank : 244)
Query Neighborhood Hits	1113	Target Neighborhood Hits	461	Shared Neighborhood Hits	226
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

TSP1_MOUSE
NC score	0.461379 (rank : 194)	θ value	1.33837e-11 (rank : 223)
Query Neighborhood Hits	1113	Target Neighborhood Hits	396	Shared Neighborhood Hits	271
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

KR105_HUMAN
NC score	0.460635 (rank : 195)	θ value	1.09739e-05 (rank : 436)
Query Neighborhood Hits	1113	Target Neighborhood Hits	271	Shared Neighborhood Hits	218
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

ITB5_HUMAN
NC score	0.458785 (rank : 196)	θ value	3.41135e-07 (rank : 370)
Query Neighborhood Hits	1113	Target Neighborhood Hits	310	Shared Neighborhood Hits	263
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

MFGM_MOUSE
NC score	0.458687 (rank : 197)	θ value	1.42992e-13 (rank : 185)
Query Neighborhood Hits	1113	Target Neighborhood Hits	233	Shared Neighborhood Hits	207
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

PSD10_HUMAN
NC score	0.458649 (rank : 198)	θ value	5.25075e-16 (rank : 150)
Query Neighborhood Hits	1113	Target Neighborhood Hits	301	Shared Neighborhood Hits	279
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

TSP1_HUMAN
NC score	0.458020 (rank : 199)	θ value	3.52202e-12 (rank : 211)
Query Neighborhood Hits	1113	Target Neighborhood Hits	389	Shared Neighborhood Hits	267
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

PSD10_MOUSE
NC score	0.457236 (rank : 200)	θ value	2.60593e-15 (rank : 156)
Query Neighborhood Hits	1113	Target Neighborhood Hits	293	Shared Neighborhood Hits	279
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ITB3_HUMAN
NC score	0.455821 (rank : 201)	θ value	1.80886e-08 (rank : 323)
Query Neighborhood Hits	1113	Target Neighborhood Hits	325	Shared Neighborhood Hits	282
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

KR511_HUMAN
NC score	0.454042 (rank : 202)	θ value	0.125558 (rank : 698)
Query Neighborhood Hits	1113	Target Neighborhood Hits	231	Shared Neighborhood Hits	186
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

ITB7_HUMAN
NC score	0.453666 (rank : 203)	θ value	1.17247e-07 (rank : 348)
Query Neighborhood Hits	1113	Target Neighborhood Hits	290	Shared Neighborhood Hits	258
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

ANR50_HUMAN
NC score	0.452627 (rank : 204)	θ value	4.58923e-20 (rank : 113)
Query Neighborhood Hits	1113	Target Neighborhood Hits	361	Shared Neighborhood Hits	288
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

ANKR6_HUMAN
NC score	0.451803 (rank : 205)	θ value	9.90251e-15 (rank : 163)
Query Neighborhood Hits	1113	Target Neighborhood Hits	439	Shared Neighborhood Hits	298
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ITB7_MOUSE
NC score	0.451232 (rank : 206)	θ value	6.43352e-06 (rank : 430)
Query Neighborhood Hits	1113	Target Neighborhood Hits	277	Shared Neighborhood Hits	245
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

ANR29_HUMAN
NC score	0.450024 (rank : 207)	θ value	2.69671e-12 (rank : 207)
Query Neighborhood Hits	1113	Target Neighborhood Hits	294	Shared Neighborhood Hits	277
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

USH2A_HUMAN
NC score	0.448848 (rank : 208)	θ value	2.43908e-13 (rank : 187)
Query Neighborhood Hits	1113	Target Neighborhood Hits	600	Shared Neighborhood Hits	290
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

ITB2_MOUSE
NC score	0.448457 (rank : 209)	θ value	1.29631e-06 (rank : 398)
Query Neighborhood Hits	1113	Target Neighborhood Hits	326	Shared Neighborhood Hits	283
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

BCL3_HUMAN
NC score	0.447306 (rank : 210)	θ value	4.59992e-12 (rank : 212)
Query Neighborhood Hits	1113	Target Neighborhood Hits	324	Shared Neighborhood Hits	285
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

HMCN1_HUMAN
NC score	0.446015 (rank : 211)	θ value	5.584e-34 (rank : 60)
Query Neighborhood Hits	1113	Target Neighborhood Hits	983	Shared Neighborhood Hits	348
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

ANR23_HUMAN
NC score	0.445224 (rank : 212)	θ value	4.16044e-13 (rank : 190)
Query Neighborhood Hits	1113	Target Neighborhood Hits	291	Shared Neighborhood Hits	277
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

ASB8_HUMAN
NC score	0.444963 (rank : 213)	θ value	1.2105e-12 (rank : 199)
Query Neighborhood Hits	1113	Target Neighborhood Hits	294	Shared Neighborhood Hits	276
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

BCL3_MOUSE
NC score	0.444618 (rank : 214)	θ value	7.84624e-12 (rank : 218)
Query Neighborhood Hits	1113	Target Neighborhood Hits	388	Shared Neighborhood Hits	307
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

ASB8_MOUSE
NC score	0.444299 (rank : 215)	θ value	2.0648e-12 (rank : 202)
Query Neighborhood Hits	1113	Target Neighborhood Hits	293	Shared Neighborhood Hits	274
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ASB3_HUMAN
NC score	0.444137 (rank : 216)	θ value	2.20605e-14 (rank : 172)
Query Neighborhood Hits	1113	Target Neighborhood Hits	316	Shared Neighborhood Hits	281
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

PCSK5_MOUSE
NC score	0.442145 (rank : 217)	θ value	1.42992e-13 (rank : 186)
Query Neighborhood Hits	1113	Target Neighborhood Hits	613	Shared Neighborhood Hits	352
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

ANR44_HUMAN
NC score	0.441760 (rank : 218)	θ value	7.32683e-18 (rank : 138)
Query Neighborhood Hits	1113	Target Neighborhood Hits	318	Shared Neighborhood Hits	286
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

KRA52_HUMAN
NC score	0.441591 (rank : 219)	θ value	0.0736092 (rank : 673)
Query Neighborhood Hits	1113	Target Neighborhood Hits	236	Shared Neighborhood Hits	194
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

ASB2_HUMAN
NC score	0.440889 (rank : 220)	θ value	9.90251e-15 (rank : 164)
Query Neighborhood Hits	1113	Target Neighborhood Hits	309	Shared Neighborhood Hits	276
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ASB16_MOUSE
NC score	0.440778 (rank : 221)	θ value	9.26847e-13 (rank : 195)
Query Neighborhood Hits	1113	Target Neighborhood Hits	306	Shared Neighborhood Hits	274
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ANR28_MOUSE
NC score	0.439831 (rank : 222)	θ value	3.63628e-17 (rank : 141)
Query Neighborhood Hits	1113	Target Neighborhood Hits	314	Shared Neighborhood Hits	285
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ASB3_MOUSE
NC score	0.439402 (rank : 223)	θ value	9.90251e-15 (rank : 165)
Query Neighborhood Hits	1113	Target Neighborhood Hits	316	Shared Neighborhood Hits	281
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ASB2_MOUSE
NC score	0.438366 (rank : 224)	θ value	3.40345e-15 (rank : 158)
Query Neighborhood Hits	1113	Target Neighborhood Hits	321	Shared Neighborhood Hits	278
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ANR16_HUMAN
NC score	0.438136 (rank : 225)	θ value	3.08544e-08 (rank : 327)
Query Neighborhood Hits	1113	Target Neighborhood Hits	286	Shared Neighborhood Hits	271
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

INVS_HUMAN
NC score	0.437792 (rank : 226)	θ value	2.88119e-14 (rank : 173)
Query Neighborhood Hits	1113	Target Neighborhood Hits	455	Shared Neighborhood Hits	302
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

PA2G6_HUMAN
NC score	0.437767 (rank : 227)	θ value	2.0648e-12 (rank : 205)
Query Neighborhood Hits	1113	Target Neighborhood Hits	284	Shared Neighborhood Hits	272
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ANR23_MOUSE
NC score	0.437722 (rank : 228)	θ value	1.47974e-10 (rank : 249)
Query Neighborhood Hits	1113	Target Neighborhood Hits	296	Shared Neighborhood Hits	274
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

ANR28_HUMAN
NC score	0.437675 (rank : 229)	θ value	6.20254e-17 (rank : 144)
Query Neighborhood Hits	1113	Target Neighborhood Hits	314	Shared Neighborhood Hits	284
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR52_MOUSE
NC score	0.436911 (rank : 230)	θ value	1.80466e-16 (rank : 146)
Query Neighborhood Hits	1113	Target Neighborhood Hits	318	Shared Neighborhood Hits	283
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

GABP3_MOUSE
NC score	0.436651 (rank : 231)	θ value	4.0297e-08 (rank : 334)
Query Neighborhood Hits	1113	Target Neighborhood Hits	330	Shared Neighborhood Hits	272
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

GABP2_MOUSE
NC score	0.436333 (rank : 232)	θ value	4.30538e-10 (rank : 260)
Query Neighborhood Hits	1113	Target Neighborhood Hits	429	Shared Neighborhood Hits	282
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

ANR52_HUMAN
NC score	0.436279 (rank : 233)	θ value	5.25075e-16 (rank : 149)
Query Neighborhood Hits	1113	Target Neighborhood Hits	322	Shared Neighborhood Hits	284
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

GABP2_HUMAN
NC score	0.435913 (rank : 234)	θ value	1.47974e-10 (rank : 251)
Query Neighborhood Hits	1113	Target Neighborhood Hits	454	Shared Neighborhood Hits	282
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

PA2G6_MOUSE
NC score	0.435872 (rank : 235)	θ value	7.09661e-13 (rank : 193)
Query Neighborhood Hits	1113	Target Neighborhood Hits	293	Shared Neighborhood Hits	275
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

INVS_MOUSE
NC score	0.435859 (rank : 236)	θ value	3.76295e-14 (rank : 175)
Query Neighborhood Hits	1113	Target Neighborhood Hits	609	Shared Neighborhood Hits	349
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

ANK1_MOUSE
NC score	0.435524 (rank : 237)	θ value	2.97466e-19 (rank : 121)
Query Neighborhood Hits	1113	Target Neighborhood Hits	430	Shared Neighborhood Hits	292
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ITB3_MOUSE
NC score	0.435225 (rank : 238)	θ value	9.92553e-07 (rank : 393)
Query Neighborhood Hits	1113	Target Neighborhood Hits	319	Shared Neighborhood Hits	272
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

TENR_MOUSE
NC score	0.434405 (rank : 239)	θ value	2.88119e-14 (rank : 174)
Query Neighborhood Hits	1113	Target Neighborhood Hits	531	Shared Neighborhood Hits	326
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

ITB1_MOUSE
NC score	0.434237 (rank : 240)	θ value	1.133e-10 (rank : 246)
Query Neighborhood Hits	1113	Target Neighborhood Hits	283	Shared Neighborhood Hits	239
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ANK1_HUMAN
NC score	0.433922 (rank : 241)	θ value	1.47631e-18 (rank : 131)
Query Neighborhood Hits	1113	Target Neighborhood Hits	416	Shared Neighborhood Hits	292
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANK3_HUMAN
NC score	0.433289 (rank : 242)	θ value	4.29542e-18 (rank : 135)
Query Neighborhood Hits	1113	Target Neighborhood Hits	853	Shared Neighborhood Hits	348
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

FANK1_HUMAN
NC score	0.433026 (rank : 243)	θ value	8.97725e-08 (rank : 347)
Query Neighborhood Hits	1113	Target Neighborhood Hits	326	Shared Neighborhood Hits	284
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

TNKS2_HUMAN
NC score	0.432901 (rank : 244)	θ value	3.07829e-16 (rank : 148)
Query Neighborhood Hits	1113	Target Neighborhood Hits	361	Shared Neighborhood Hits	285
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

TNKS1_HUMAN
NC score	0.432762 (rank : 245)	θ value	4.91457e-14 (rank : 180)
Query Neighborhood Hits	1113	Target Neighborhood Hits	477	Shared Neighborhood Hits	317
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

ITB1_HUMAN
NC score	0.431104 (rank : 246)	θ value	2.98157e-11 (rank : 229)
Query Neighborhood Hits	1113	Target Neighborhood Hits	298	Shared Neighborhood Hits	251
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB2_HUMAN
NC score	0.430992 (rank : 247)	θ value	3.29651e-10 (rank : 256)
Query Neighborhood Hits	1113	Target Neighborhood Hits	282	Shared Neighborhood Hits	245
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ASB10_MOUSE
NC score	0.430651 (rank : 248)	θ value	1.38499e-08 (rank : 312)
Query Neighborhood Hits	1113	Target Neighborhood Hits	301	Shared Neighborhood Hits	276
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ASB14_MOUSE
NC score	0.429687 (rank : 249)	θ value	1.42992e-13 (rank : 184)
Query Neighborhood Hits	1113	Target Neighborhood Hits	293	Shared Neighborhood Hits	271
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

PGBM_MOUSE
NC score	0.428999 (rank : 250)	θ value	6.85773e-16 (rank : 153)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1073	Shared Neighborhood Hits	411
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

ANKR1_HUMAN
NC score	0.428961 (rank : 251)	θ value	8.11959e-09 (rank : 304)
Query Neighborhood Hits	1113	Target Neighborhood Hits	308	Shared Neighborhood Hits	271
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

IKBA_HUMAN
NC score	0.428871 (rank : 252)	θ value	1.38499e-08 (rank : 314)
Query Neighborhood Hits	1113	Target Neighborhood Hits	280	Shared Neighborhood Hits	272
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

ASZ1_MOUSE
NC score	0.428446 (rank : 253)	θ value	6.21693e-09 (rank : 302)
Query Neighborhood Hits	1113	Target Neighborhood Hits	319	Shared Neighborhood Hits	269
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

TENR_HUMAN
NC score	0.427380 (rank : 254)	θ value	1.29331e-14 (rank : 169)
Query Neighborhood Hits	1113	Target Neighborhood Hits	526	Shared Neighborhood Hits	321
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

ITB4_HUMAN
NC score	0.427369 (rank : 255)	θ value	1.47974e-10 (rank : 252)
Query Neighborhood Hits	1113	Target Neighborhood Hits	458	Shared Neighborhood Hits	271
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

TRPA1_MOUSE
NC score	0.427199 (rank : 256)	θ value	6.64225e-11 (rank : 242)
Query Neighborhood Hits	1113	Target Neighborhood Hits	343	Shared Neighborhood Hits	282
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

ANKR2_MOUSE
NC score	0.426945 (rank : 257)	θ value	1.80886e-08 (rank : 320)
Query Neighborhood Hits	1113	Target Neighborhood Hits	312	Shared Neighborhood Hits	276
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

AN36B_HUMAN
NC score	0.426729 (rank : 258)	θ value	1.2105e-12 (rank : 197)
Query Neighborhood Hits	1113	Target Neighborhood Hits	294	Shared Neighborhood Hits	268
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

KRA56_HUMAN
NC score	0.426643 (rank : 259)	θ value	0.62314 (rank : 800)
Query Neighborhood Hits	1113	Target Neighborhood Hits	207	Shared Neighborhood Hits	173
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

PP16A_MOUSE
NC score	0.426600 (rank : 260)	θ value	5.43371e-13 (rank : 192)
Query Neighborhood Hits	1113	Target Neighborhood Hits	318	Shared Neighborhood Hits	275
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

CDN2D_MOUSE
NC score	0.426599 (rank : 261)	θ value	3.41135e-07 (rank : 367)
Query Neighborhood Hits	1113	Target Neighborhood Hits	267	Shared Neighborhood Hits	260
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ASB10_HUMAN
NC score	0.426295 (rank : 262)	θ value	4.0297e-08 (rank : 332)
Query Neighborhood Hits	1113	Target Neighborhood Hits	291	Shared Neighborhood Hits	273
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

LAMA4_MOUSE
NC score	0.425916 (rank : 263)	θ value	3.19293e-05 (rank : 457)
Query Neighborhood Hits	1113	Target Neighborhood Hits	584	Shared Neighborhood Hits	239
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

KR109_HUMAN
NC score	0.425774 (rank : 264)	θ value	0.00035302 (rank : 500)
Query Neighborhood Hits	1113	Target Neighborhood Hits	226	Shared Neighborhood Hits	191
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

FANK1_MOUSE
NC score	0.425769 (rank : 265)	θ value	4.92598e-06 (rank : 422)
Query Neighborhood Hits	1113	Target Neighborhood Hits	325	Shared Neighborhood Hits	282
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

ASB7_MOUSE
NC score	0.425712 (rank : 266)	θ value	1.99992e-07 (rank : 356)
Query Neighborhood Hits	1113	Target Neighborhood Hits	296	Shared Neighborhood Hits	272
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

CDN2C_HUMAN
NC score	0.425688 (rank : 267)	θ value	6.43352e-06 (rank : 428)
Query Neighborhood Hits	1113	Target Neighborhood Hits	262	Shared Neighborhood Hits	255
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

ASB7_HUMAN
NC score	0.425666 (rank : 268)	θ value	1.99992e-07 (rank : 355)
Query Neighborhood Hits	1113	Target Neighborhood Hits	296	Shared Neighborhood Hits	272
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

FATH_HUMAN
NC score	0.425414 (rank : 269)	θ value	6.82597e-32 (rank : 61)
Query Neighborhood Hits	1113	Target Neighborhood Hits	570	Shared Neighborhood Hits	353
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

ANKR1_MOUSE
NC score	0.425364 (rank : 270)	θ value	5.26297e-08 (rank : 337)
Query Neighborhood Hits	1113	Target Neighborhood Hits	316	Shared Neighborhood Hits	276
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

ASB15_HUMAN
NC score	0.425193 (rank : 271)	θ value	1.74796e-11 (rank : 225)
Query Neighborhood Hits	1113	Target Neighborhood Hits	305	Shared Neighborhood Hits	273
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

KR10C_HUMAN
NC score	0.425136 (rank : 272)	θ value	7.59969e-07 (rank : 383)
Query Neighborhood Hits	1113	Target Neighborhood Hits	219	Shared Neighborhood Hits	181
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

CDN2D_HUMAN
NC score	0.424811 (rank : 273)	θ value	3.41135e-07 (rank : 366)
Query Neighborhood Hits	1113	Target Neighborhood Hits	268	Shared Neighborhood Hits	261
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ANR42_MOUSE
NC score	0.424586 (rank : 274)	θ value	1.133e-10 (rank : 245)
Query Neighborhood Hits	1113	Target Neighborhood Hits	334	Shared Neighborhood Hits	272
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

PGBM_HUMAN
NC score	0.424560 (rank : 275)	θ value	4.91457e-14 (rank : 179)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1113	Shared Neighborhood Hits	425
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

ASB16_HUMAN
NC score	0.424349 (rank : 276)	θ value	5.08577e-11 (rank : 233)
Query Neighborhood Hits	1113	Target Neighborhood Hits	286	Shared Neighborhood Hits	268
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

KR108_HUMAN
NC score	0.424122 (rank : 277)	θ value	8.40245e-06 (rank : 433)
Query Neighborhood Hits	1113	Target Neighborhood Hits	226	Shared Neighborhood Hits	181
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

ANR49_HUMAN
NC score	0.423989 (rank : 278)	θ value	1.29631e-06 (rank : 395)
Query Neighborhood Hits	1113	Target Neighborhood Hits	282	Shared Neighborhood Hits	266
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

ASZ1_HUMAN
NC score	0.423905 (rank : 279)	θ value	2.79066e-09 (rank : 289)
Query Neighborhood Hits	1113	Target Neighborhood Hits	341	Shared Neighborhood Hits	268
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ANR39_HUMAN
NC score	0.423692 (rank : 280)	θ value	3.77169e-06 (rank : 417)
Query Neighborhood Hits	1113	Target Neighborhood Hits	285	Shared Neighborhood Hits	274
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANKR2_HUMAN
NC score	0.423506 (rank : 281)	θ value	8.97725e-08 (rank : 342)
Query Neighborhood Hits	1113	Target Neighborhood Hits	321	Shared Neighborhood Hits	277
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

MYPT1_MOUSE
NC score	0.423495 (rank : 282)	θ value	1.68911e-14 (rank : 171)
Query Neighborhood Hits	1113	Target Neighborhood Hits	539	Shared Neighborhood Hits	292
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

ANR49_MOUSE
NC score	0.423420 (rank : 283)	θ value	7.59969e-07 (rank : 381)
Query Neighborhood Hits	1113	Target Neighborhood Hits	285	Shared Neighborhood Hits	268
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

TRPA1_HUMAN
NC score	0.423217 (rank : 284)	θ value	4.30538e-10 (rank : 264)
Query Neighborhood Hits	1113	Target Neighborhood Hits	339	Shared Neighborhood Hits	281
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

TSP2_HUMAN
NC score	0.422246 (rank : 285)	θ value	1.63604e-09 (rank : 279)
Query Neighborhood Hits	1113	Target Neighborhood Hits	359	Shared Neighborhood Hits	256
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

RN5A_HUMAN
NC score	0.422119 (rank : 286)	θ value	1.2105e-12 (rank : 200)
Query Neighborhood Hits	1113	Target Neighborhood Hits	608	Shared Neighborhood Hits	282
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ANKS3_HUMAN
NC score	0.421980 (rank : 287)	θ value	2.13673e-09 (rank : 281)
Query Neighborhood Hits	1113	Target Neighborhood Hits	355	Shared Neighborhood Hits	269
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

IKBE_MOUSE
NC score	0.421502 (rank : 288)	θ value	7.59969e-07 (rank : 382)
Query Neighborhood Hits	1113	Target Neighborhood Hits	308	Shared Neighborhood Hits	275
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

IKBA_MOUSE
NC score	0.421174 (rank : 289)	θ value	2.61198e-07 (rank : 364)
Query Neighborhood Hits	1113	Target Neighborhood Hits	283	Shared Neighborhood Hits	274
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

ANKS3_MOUSE
NC score	0.421084 (rank : 290)	θ value	6.21693e-09 (rank : 301)
Query Neighborhood Hits	1113	Target Neighborhood Hits	355	Shared Neighborhood Hits	272
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ANR42_HUMAN
NC score	0.420992 (rank : 291)	θ value	1.80886e-08 (rank : 321)
Query Neighborhood Hits	1113	Target Neighborhood Hits	284	Shared Neighborhood Hits	269
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

CDN2C_MOUSE
NC score	0.420610 (rank : 292)	θ value	7.1131e-05 (rank : 465)
Query Neighborhood Hits	1113	Target Neighborhood Hits	270	Shared Neighborhood Hits	260
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

ANKR7_HUMAN
NC score	0.420051 (rank : 293)	θ value	4.92598e-06 (rank : 420)
Query Neighborhood Hits	1113	Target Neighborhood Hits	286	Shared Neighborhood Hits	269
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

IKBE_HUMAN
NC score	0.419839 (rank : 294)	θ value	9.92553e-07 (rank : 390)
Query Neighborhood Hits	1113	Target Neighborhood Hits	288	Shared Neighborhood Hits	270
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

PP16A_HUMAN
NC score	0.418786 (rank : 295)	θ value	2.52405e-10 (rank : 255)
Query Neighborhood Hits	1113	Target Neighborhood Hits	340	Shared Neighborhood Hits	279
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

ATRN_MOUSE
NC score	0.418740 (rank : 296)	θ value	1.53129e-07 (rank : 351)
Query Neighborhood Hits	1113	Target Neighborhood Hits	519	Shared Neighborhood Hits	301
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

CFC1_HUMAN
NC score	0.418101 (rank : 297)	θ value	0.0193708 (rank : 617)
Query Neighborhood Hits	1113	Target Neighborhood Hits	148	Shared Neighborhood Hits	146
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

ATRN_HUMAN
NC score	0.417792 (rank : 298)	θ value	1.99992e-07 (rank : 357)
Query Neighborhood Hits	1113	Target Neighborhood Hits	525	Shared Neighborhood Hits	302
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ANR39_MOUSE
NC score	0.417373 (rank : 299)	θ value	2.44474e-05 (rank : 447)
Query Neighborhood Hits	1113	Target Neighborhood Hits	284	Shared Neighborhood Hits	272
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANKS1_HUMAN
NC score	0.416967 (rank : 300)	θ value	9.26847e-13 (rank : 194)
Query Neighborhood Hits	1113	Target Neighborhood Hits	438	Shared Neighborhood Hits	290
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

SSPO_MOUSE
NC score	0.416913 (rank : 301)	θ value	7.34386e-10 (rank : 271)
Query Neighborhood Hits	1113	Target Neighborhood Hits	800	Shared Neighborhood Hits	419
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

ASB15_MOUSE
NC score	0.416448 (rank : 302)	θ value	1.80886e-08 (rank : 322)
Query Neighborhood Hits	1113	Target Neighborhood Hits	292	Shared Neighborhood Hits	268
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

PP16B_HUMAN
NC score	0.416413 (rank : 303)	θ value	3.89403e-11 (rank : 232)
Query Neighborhood Hits	1113	Target Neighborhood Hits	307	Shared Neighborhood Hits	275
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

LAMA3_HUMAN
NC score	0.416356 (rank : 304)	θ value	1.43324e-05 (rank : 443)
Query Neighborhood Hits	1113	Target Neighborhood Hits	760	Shared Neighborhood Hits	279
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

TSP2_MOUSE
NC score	0.416098 (rank : 305)	θ value	6.64225e-11 (rank : 243)
Query Neighborhood Hits	1113	Target Neighborhood Hits	352	Shared Neighborhood Hits	252
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

ANKS6_MOUSE
NC score	0.415921 (rank : 306)	θ value	4.76016e-09 (rank : 294)
Query Neighborhood Hits	1113	Target Neighborhood Hits	435	Shared Neighborhood Hits	302
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

MYPT2_HUMAN
NC score	0.415834 (rank : 307)	θ value	2.0648e-12 (rank : 204)
Query Neighborhood Hits	1113	Target Neighborhood Hits	707	Shared Neighborhood Hits	292
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

MIB1_HUMAN
NC score	0.415459 (rank : 308)	θ value	4.59992e-12 (rank : 213)
Query Neighborhood Hits	1113	Target Neighborhood Hits	470	Shared Neighborhood Hits	294
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

CT086_HUMAN
NC score	0.415337 (rank : 309)	θ value	3.41135e-07 (rank : 368)
Query Neighborhood Hits	1113	Target Neighborhood Hits	277	Shared Neighborhood Hits	265
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

EHMT2_HUMAN
NC score	0.414813 (rank : 310)	θ value	7.58209e-15 (rank : 160)
Query Neighborhood Hits	1113	Target Neighborhood Hits	498	Shared Neighborhood Hits	311
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

PP16B_MOUSE
NC score	0.414756 (rank : 311)	θ value	6.64225e-11 (rank : 241)
Query Neighborhood Hits	1113	Target Neighborhood Hits	302	Shared Neighborhood Hits	273
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

MIB1_MOUSE
NC score	0.414612 (rank : 312)	θ value	4.59992e-12 (rank : 214)
Query Neighborhood Hits	1113	Target Neighborhood Hits	471	Shared Neighborhood Hits	292
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

MIB2_HUMAN
NC score	0.414569 (rank : 313)	θ value	3.29651e-10 (rank : 257)
Query Neighborhood Hits	1113	Target Neighborhood Hits	438	Shared Neighborhood Hits	287
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

CSKI1_MOUSE
NC score	0.414543 (rank : 314)	θ value	2.28291e-11 (rank : 227)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1031	Shared Neighborhood Hits	446
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

MYPT1_HUMAN
NC score	0.413832 (rank : 315)	θ value	4.91457e-14 (rank : 178)
Query Neighborhood Hits	1113	Target Neighborhood Hits	723	Shared Neighborhood Hits	296
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

KR10B_HUMAN
NC score	0.412807 (rank : 316)	θ value	0.000158464 (rank : 480)
Query Neighborhood Hits	1113	Target Neighborhood Hits	269	Shared Neighborhood Hits	214
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

ANR46_HUMAN
NC score	0.412470 (rank : 317)	θ value	9.29e-05 (rank : 467)
Query Neighborhood Hits	1113	Target Neighborhood Hits	281	Shared Neighborhood Hits	269
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ANR46_MOUSE
NC score	0.411821 (rank : 318)	θ value	0.000121331 (rank : 473)
Query Neighborhood Hits	1113	Target Neighborhood Hits	274	Shared Neighborhood Hits	263
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ANKS6_HUMAN
NC score	0.411753 (rank : 319)	θ value	8.97725e-08 (rank : 343)
Query Neighborhood Hits	1113	Target Neighborhood Hits	411	Shared Neighborhood Hits	296
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ANK2_HUMAN
NC score	0.411404 (rank : 320)	θ value	4.29542e-18 (rank : 134)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1615	Shared Neighborhood Hits	445
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

EHMT1_HUMAN
NC score	0.411182 (rank : 321)	θ value	6.00763e-12 (rank : 215)
Query Neighborhood Hits	1113	Target Neighborhood Hits	417	Shared Neighborhood Hits	299
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

ASB13_MOUSE
NC score	0.410077 (rank : 322)	θ value	1.99992e-07 (rank : 354)
Query Neighborhood Hits	1113	Target Neighborhood Hits	293	Shared Neighborhood Hits	274
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ANR35_HUMAN
NC score	0.409982 (rank : 323)	θ value	7.84624e-12 (rank : 217)
Query Neighborhood Hits	1113	Target Neighborhood Hits	784	Shared Neighborhood Hits	302
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

CSKI1_HUMAN
NC score	0.409594 (rank : 324)	θ value	6.64225e-11 (rank : 238)
Query Neighborhood Hits	1113	Target Neighborhood Hits	997	Shared Neighborhood Hits	406
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

EHMT2_MOUSE
NC score	0.408895 (rank : 325)	θ value	8.38298e-14 (rank : 183)
Query Neighborhood Hits	1113	Target Neighborhood Hits	750	Shared Neighborhood Hits	376
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ASB13_HUMAN
NC score	0.408326 (rank : 326)	θ value	5.81887e-07 (rank : 377)
Query Neighborhood Hits	1113	Target Neighborhood Hits	293	Shared Neighborhood Hits	275
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

FRAS1_HUMAN
NC score	0.407340 (rank : 327)	θ value	2.13673e-09 (rank : 284)
Query Neighborhood Hits	1113	Target Neighborhood Hits	759	Shared Neighborhood Hits	345
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

ANR19_HUMAN
NC score	0.406662 (rank : 328)	θ value	2.61198e-07 (rank : 360)
Query Neighborhood Hits	1113	Target Neighborhood Hits	276	Shared Neighborhood Hits	262
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

ANKS1_MOUSE
NC score	0.405870 (rank : 329)	θ value	6.87365e-08 (rank : 339)
Query Neighborhood Hits	1113	Target Neighborhood Hits	453	Shared Neighborhood Hits	297
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ANKR5_MOUSE
NC score	0.405839 (rank : 330)	θ value	3.77169e-06 (rank : 416)
Query Neighborhood Hits	1113	Target Neighborhood Hits	298	Shared Neighborhood Hits	274
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANR15_HUMAN
NC score	0.405270 (rank : 331)	θ value	2.28291e-11 (rank : 226)
Query Neighborhood Hits	1113	Target Neighborhood Hits	478	Shared Neighborhood Hits	276
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

MTPN_MOUSE
NC score	0.404746 (rank : 332)	θ value	0.00134147 (rank : 523)
Query Neighborhood Hits	1113	Target Neighborhood Hits	269	Shared Neighborhood Hits	259
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

MIB2_MOUSE
NC score	0.404066 (rank : 333)	θ value	1.38499e-08 (rank : 316)
Query Neighborhood Hits	1113	Target Neighborhood Hits	409	Shared Neighborhood Hits	282
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

LAMA4_HUMAN
NC score	0.403970 (rank : 334)	θ value	2.21117e-06 (rank : 409)
Query Neighborhood Hits	1113	Target Neighborhood Hits	708	Shared Neighborhood Hits	245
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

MTPN_HUMAN
NC score	0.403325 (rank : 335)	θ value	0.00134147 (rank : 522)
Query Neighborhood Hits	1113	Target Neighborhood Hits	269	Shared Neighborhood Hits	259
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

ANFY1_MOUSE
NC score	0.403159 (rank : 336)	θ value	1.29331e-14 (rank : 167)
Query Neighborhood Hits	1113	Target Neighborhood Hits	480	Shared Neighborhood Hits	287
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANFY1_HUMAN
NC score	0.402684 (rank : 337)	θ value	1.29331e-14 (rank : 166)
Query Neighborhood Hits	1113	Target Neighborhood Hits	480	Shared Neighborhood Hits	283
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANR22_HUMAN
NC score	0.402462 (rank : 338)	θ value	0.00298849 (rank : 544)
Query Neighborhood Hits	1113	Target Neighborhood Hits	243	Shared Neighborhood Hits	236
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ANR47_MOUSE
NC score	0.400942 (rank : 339)	θ value	2.79066e-09 (rank : 288)
Query Neighborhood Hits	1113	Target Neighborhood Hits	350	Shared Neighborhood Hits	257
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ACBD6_MOUSE
NC score	0.400556 (rank : 340)	θ value	1.87187e-05 (rank : 445)
Query Neighborhood Hits	1113	Target Neighborhood Hits	305	Shared Neighborhood Hits	273
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

POTE8_HUMAN
NC score	0.399430 (rank : 341)	θ value	3.41135e-07 (rank : 371)
Query Neighborhood Hits	1113	Target Neighborhood Hits	337	Shared Neighborhood Hits	278
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

ASB4_MOUSE
NC score	0.399189 (rank : 342)	θ value	2.44474e-05 (rank : 448)
Query Neighborhood Hits	1113	Target Neighborhood Hits	265	Shared Neighborhood Hits	253
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

CFC1_MOUSE
NC score	0.398171 (rank : 343)	θ value	0.0148317 (rank : 605)
Query Neighborhood Hits	1113	Target Neighborhood Hits	125	Shared Neighborhood Hits	124
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

ANKR5_HUMAN
NC score	0.398106 (rank : 344)	θ value	7.1131e-05 (rank : 463)
Query Neighborhood Hits	1113	Target Neighborhood Hits	297	Shared Neighborhood Hits	271
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ASB4_HUMAN
NC score	0.398030 (rank : 345)	θ value	3.19293e-05 (rank : 456)
Query Neighborhood Hits	1113	Target Neighborhood Hits	264	Shared Neighborhood Hits	253
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ACBD6_HUMAN
NC score	0.397946 (rank : 346)	θ value	4.1701e-05 (rank : 459)
Query Neighborhood Hits	1113	Target Neighborhood Hits	304	Shared Neighborhood Hits	273
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

CSKI2_MOUSE
NC score	0.397776 (rank : 347)	θ value	4.0297e-08 (rank : 333)
Query Neighborhood Hits	1113	Target Neighborhood Hits	812	Shared Neighborhood Hits	370
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

AN36A_HUMAN
NC score	0.397296 (rank : 348)	θ value	9.92553e-07 (rank : 387)
Query Neighborhood Hits	1113	Target Neighborhood Hits	271	Shared Neighborhood Hits	260
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ANRA2_MOUSE
NC score	0.396371 (rank : 349)	θ value	3.19293e-05 (rank : 455)
Query Neighborhood Hits	1113	Target Neighborhood Hits	287	Shared Neighborhood Hits	264
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ASB1_HUMAN
NC score	0.396217 (rank : 350)	θ value	9.92553e-07 (rank : 388)
Query Neighborhood Hits	1113	Target Neighborhood Hits	291	Shared Neighborhood Hits	264
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

IKBB_HUMAN
NC score	0.396006 (rank : 351)	θ value	9.29e-05 (rank : 469)
Query Neighborhood Hits	1113	Target Neighborhood Hits	284	Shared Neighborhood Hits	270
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

IKBB_MOUSE
NC score	0.395853 (rank : 352)	θ value	0.00298849 (rank : 546)
Query Neighborhood Hits	1113	Target Neighborhood Hits	284	Shared Neighborhood Hits	273
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

CSKI2_HUMAN
NC score	0.395459 (rank : 353)	θ value	8.97725e-08 (rank : 346)
Query Neighborhood Hits	1113	Target Neighborhood Hits	747	Shared Neighborhood Hits	348
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CD2A1_MOUSE
NC score	0.394781 (rank : 354)	θ value	2.61198e-07 (rank : 362)
Query Neighborhood Hits	1113	Target Neighborhood Hits	206	Shared Neighborhood Hits	199
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

ASB1_MOUSE
NC score	0.394258 (rank : 355)	θ value	1.69304e-06 (rank : 401)
Query Neighborhood Hits	1113	Target Neighborhood Hits	292	Shared Neighborhood Hits	262
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ANR41_HUMAN
NC score	0.393240 (rank : 356)	θ value	4.92598e-06 (rank : 421)
Query Neighborhood Hits	1113	Target Neighborhood Hits	332	Shared Neighborhood Hits	256
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

ANRA2_HUMAN
NC score	0.393224 (rank : 357)	θ value	7.1131e-05 (rank : 464)
Query Neighborhood Hits	1113	Target Neighborhood Hits	288	Shared Neighborhood Hits	265
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANR47_HUMAN
NC score	0.392785 (rank : 358)	θ value	4.76016e-09 (rank : 295)
Query Neighborhood Hits	1113	Target Neighborhood Hits	369	Shared Neighborhood Hits	255
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ANR10_HUMAN
NC score	0.392763 (rank : 359)	θ value	0.000602161 (rank : 505)
Query Neighborhood Hits	1113	Target Neighborhood Hits	289	Shared Neighborhood Hits	262
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

RN5A_MOUSE
NC score	0.392431 (rank : 360)	θ value	3.76295e-14 (rank : 176)
Query Neighborhood Hits	1113	Target Neighborhood Hits	899	Shared Neighborhood Hits	300
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

KR510_HUMAN
NC score	0.391733 (rank : 361)	θ value	1.06291 (rank : 843)
Query Neighborhood Hits	1113	Target Neighborhood Hits	217	Shared Neighborhood Hits	169
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

ANR10_MOUSE
NC score	0.390706 (rank : 362)	θ value	0.00035302 (rank : 497)
Query Neighborhood Hits	1113	Target Neighborhood Hits	273	Shared Neighborhood Hits	261
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

FRAS1_MOUSE
NC score	0.390023 (rank : 363)	θ value	1.47974e-10 (rank : 250)
Query Neighborhood Hits	1113	Target Neighborhood Hits	747	Shared Neighborhood Hits	330
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

RFXK_HUMAN
NC score	0.389894 (rank : 364)	θ value	0.00134147 (rank : 526)
Query Neighborhood Hits	1113	Target Neighborhood Hits	282	Shared Neighborhood Hits	261
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

ASB6_MOUSE
NC score	0.389339 (rank : 365)	θ value	6.43352e-06 (rank : 427)
Query Neighborhood Hits	1113	Target Neighborhood Hits	264	Shared Neighborhood Hits	246
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ASB11_HUMAN
NC score	0.388536 (rank : 366)	θ value	2.21117e-06 (rank : 404)
Query Neighborhood Hits	1113	Target Neighborhood Hits	271	Shared Neighborhood Hits	255
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

USH1G_MOUSE
NC score	0.386767 (rank : 367)	θ value	7.59969e-07 (rank : 386)
Query Neighborhood Hits	1113	Target Neighborhood Hits	271	Shared Neighborhood Hits	257
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

USH1G_HUMAN
NC score	0.386332 (rank : 368)	θ value	1.69304e-06 (rank : 403)
Query Neighborhood Hits	1113	Target Neighborhood Hits	267	Shared Neighborhood Hits	256
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

TDGF1_MOUSE
NC score	0.385884 (rank : 369)	θ value	0.0330416 (rank : 644)
Query Neighborhood Hits	1113	Target Neighborhood Hits	146	Shared Neighborhood Hits	144
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

LYAM3_MOUSE
NC score	0.385640 (rank : 370)	θ value	1.17247e-07 (rank : 349)
Query Neighborhood Hits	1113	Target Neighborhood Hits	390	Shared Neighborhood Hits	262
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

CELR2_HUMAN
NC score	0.385471 (rank : 371)	θ value	9.56915e-18 (rank : 139)
Query Neighborhood Hits	1113	Target Neighborhood Hits	657	Shared Neighborhood Hits	382
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

SHAN1_HUMAN
NC score	0.385346 (rank : 372)	θ value	3.52202e-12 (rank : 210)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1041	Shared Neighborhood Hits	352
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

ASB12_HUMAN
NC score	0.384893 (rank : 373)	θ value	0.00665767 (rank : 570)
Query Neighborhood Hits	1113	Target Neighborhood Hits	263	Shared Neighborhood Hits	255
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ZDH13_HUMAN
NC score	0.384138 (rank : 374)	θ value	2.13673e-09 (rank : 287)
Query Neighborhood Hits	1113	Target Neighborhood Hits	322	Shared Neighborhood Hits	273
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

CELR3_HUMAN
NC score	0.384032 (rank : 375)	θ value	2.43343e-21 (rank : 102)
Query Neighborhood Hits	1113	Target Neighborhood Hits	680	Shared Neighborhood Hits	366
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

ANR38_HUMAN
NC score	0.383952 (rank : 376)	θ value	8.11959e-09 (rank : 305)
Query Neighborhood Hits	1113	Target Neighborhood Hits	443	Shared Neighborhood Hits	253
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ELTD1_HUMAN
NC score	0.383152 (rank : 377)	θ value	2.21117e-06 (rank : 406)
Query Neighborhood Hits	1113	Target Neighborhood Hits	269	Shared Neighborhood Hits	188
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

BARD1_HUMAN
NC score	0.382860 (rank : 378)	θ value	1.29631e-06 (rank : 396)
Query Neighborhood Hits	1113	Target Neighborhood Hits	427	Shared Neighborhood Hits	282
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ASB5_HUMAN
NC score	0.382753 (rank : 379)	θ value	0.000158464 (rank : 478)
Query Neighborhood Hits	1113	Target Neighborhood Hits	283	Shared Neighborhood Hits	264
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ASB11_MOUSE
NC score	0.382491 (rank : 380)	θ value	0.00020696 (rank : 484)
Query Neighborhood Hits	1113	Target Neighborhood Hits	271	Shared Neighborhood Hits	252
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ASB12_MOUSE
NC score	0.381483 (rank : 381)	θ value	0.00665767 (rank : 571)
Query Neighborhood Hits	1113	Target Neighborhood Hits	261	Shared Neighborhood Hits	252
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ZDH17_HUMAN
NC score	0.380160 (rank : 382)	θ value	1.06045e-08 (rank : 311)
Query Neighborhood Hits	1113	Target Neighborhood Hits	334	Shared Neighborhood Hits	275
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

RFXK_MOUSE
NC score	0.379955 (rank : 383)	θ value	0.0113563 (rank : 599)
Query Neighborhood Hits	1113	Target Neighborhood Hits	273	Shared Neighborhood Hits	258
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

SORL_MOUSE
NC score	0.379833 (rank : 384)	θ value	4.30538e-10 (rank : 262)
Query Neighborhood Hits	1113	Target Neighborhood Hits	439	Shared Neighborhood Hits	260
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

ASB5_MOUSE
NC score	0.379450 (rank : 385)	θ value	0.00102713 (rank : 513)
Query Neighborhood Hits	1113	Target Neighborhood Hits	266	Shared Neighborhood Hits	255
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

CELR3_MOUSE
NC score	0.378787 (rank : 386)	θ value	1.02238e-19 (rank : 119)
Query Neighborhood Hits	1113	Target Neighborhood Hits	687	Shared Neighborhood Hits	373
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

ZDH13_MOUSE
NC score	0.378612 (rank : 387)	θ value	3.08544e-08 (rank : 330)
Query Neighborhood Hits	1113	Target Neighborhood Hits	329	Shared Neighborhood Hits	276
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

ASB6_HUMAN
NC score	0.378473 (rank : 388)	θ value	0.00035302 (rank : 498)
Query Neighborhood Hits	1113	Target Neighborhood Hits	256	Shared Neighborhood Hits	248
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ANR25_HUMAN
NC score	0.378206 (rank : 389)	θ value	3.08544e-08 (rank : 328)
Query Neighborhood Hits	1113	Target Neighborhood Hits	350	Shared Neighborhood Hits	263
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

ANR21_HUMAN
NC score	0.377838 (rank : 390)	θ value	4.30538e-10 (rank : 259)
Query Neighborhood Hits	1113	Target Neighborhood Hits	864	Shared Neighborhood Hits	299
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

ANS4B_HUMAN
NC score	0.377757 (rank : 391)	θ value	0.00020696 (rank : 483)
Query Neighborhood Hits	1113	Target Neighborhood Hits	289	Shared Neighborhood Hits	254
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ZDH17_MOUSE
NC score	0.376571 (rank : 392)	θ value	3.08544e-08 (rank : 331)
Query Neighborhood Hits	1113	Target Neighborhood Hits	328	Shared Neighborhood Hits	270
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

NFKB1_HUMAN
NC score	0.376494 (rank : 393)	θ value	4.30538e-10 (rank : 261)
Query Neighborhood Hits	1113	Target Neighborhood Hits	306	Shared Neighborhood Hits	273
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

POT15_HUMAN
NC score	0.376348 (rank : 394)	θ value	5.62301e-10 (rank : 266)
Query Neighborhood Hits	1113	Target Neighborhood Hits	893	Shared Neighborhood Hits	301
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

KRA94_HUMAN
NC score	0.376175 (rank : 395)	θ value	0.00020696 (rank : 489)
Query Neighborhood Hits	1113	Target Neighborhood Hits	204	Shared Neighborhood Hits	173
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KRA93_HUMAN
NC score	0.376114 (rank : 396)	θ value	1.43324e-05 (rank : 442)
Query Neighborhood Hits	1113	Target Neighborhood Hits	203	Shared Neighborhood Hits	160
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

ANR38_MOUSE
NC score	0.375372 (rank : 397)	θ value	2.52405e-10 (rank : 254)
Query Neighborhood Hits	1113	Target Neighborhood Hits	512	Shared Neighborhood Hits	247
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ASB9_HUMAN
NC score	0.375075 (rank : 398)	θ value	0.0736092 (rank : 670)
Query Neighborhood Hits	1113	Target Neighborhood Hits	267	Shared Neighborhood Hits	251
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

NFKB1_MOUSE
NC score	0.374845 (rank : 399)	θ value	6.87365e-08 (rank : 341)
Query Neighborhood Hits	1113	Target Neighborhood Hits	300	Shared Neighborhood Hits	265
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

BARD1_MOUSE
NC score	0.373615 (rank : 400)	θ value	0.00228821 (rank : 538)
Query Neighborhood Hits	1113	Target Neighborhood Hits	411	Shared Neighborhood Hits	276
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ASB9_MOUSE
NC score	0.372982 (rank : 401)	θ value	0.365318 (rank : 752)
Query Neighborhood Hits	1113	Target Neighborhood Hits	257	Shared Neighborhood Hits	248
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

ITB8_HUMAN
NC score	0.372505 (rank : 402)	θ value	0.000270298 (rank : 492)
Query Neighborhood Hits	1113	Target Neighborhood Hits	280	Shared Neighborhood Hits	234
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

NFKB2_HUMAN
NC score	0.371427 (rank : 403)	θ value	1.38499e-08 (rank : 317)
Query Neighborhood Hits	1113	Target Neighborhood Hits	325	Shared Neighborhood Hits	278
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ANS4B_MOUSE
NC score	0.370536 (rank : 404)	θ value	0.000602161 (rank : 506)
Query Neighborhood Hits	1113	Target Neighborhood Hits	294	Shared Neighborhood Hits	250
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

CELR1_MOUSE
NC score	0.369801 (rank : 405)	θ value	6.40375e-22 (rank : 98)
Query Neighborhood Hits	1113	Target Neighborhood Hits	617	Shared Neighborhood Hits	337
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

KRA13_HUMAN
NC score	0.369566 (rank : 406)	θ value	0.0431538 (rank : 649)
Query Neighborhood Hits	1113	Target Neighborhood Hits	144	Shared Neighborhood Hits	123
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

TENN_MOUSE
NC score	0.369074 (rank : 407)	θ value	6.00763e-12 (rank : 216)
Query Neighborhood Hits	1113	Target Neighborhood Hits	484	Shared Neighborhood Hits	286
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

KRA44_HUMAN
NC score	0.369028 (rank : 408)	θ value	0.00020696 (rank : 488)
Query Neighborhood Hits	1113	Target Neighborhood Hits	162	Shared Neighborhood Hits	130
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

CDN2B_MOUSE
NC score	0.368777 (rank : 409)	θ value	8.40245e-06 (rank : 432)
Query Neighborhood Hits	1113	Target Neighborhood Hits	201	Shared Neighborhood Hits	197
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

SORL_HUMAN
NC score	0.368558 (rank : 410)	θ value	7.34386e-10 (rank : 270)
Query Neighborhood Hits	1113	Target Neighborhood Hits	440	Shared Neighborhood Hits	251
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

CELR1_HUMAN
NC score	0.368497 (rank : 411)	θ value	5.07402e-19 (rank : 122)
Query Neighborhood Hits	1113	Target Neighborhood Hits	613	Shared Neighborhood Hits	335
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

ANR25_MOUSE
NC score	0.367542 (rank : 412)	θ value	5.81887e-07 (rank : 376)
Query Neighborhood Hits	1113	Target Neighborhood Hits	398	Shared Neighborhood Hits	281
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

ANR33_MOUSE
NC score	0.367200 (rank : 413)	θ value	0.00665767 (rank : 568)
Query Neighborhood Hits	1113	Target Neighborhood Hits	225	Shared Neighborhood Hits	219
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

KRA98_HUMAN
NC score	0.366712 (rank : 414)	θ value	0.00665767 (rank : 575)
Query Neighborhood Hits	1113	Target Neighborhood Hits	185	Shared Neighborhood Hits	146
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

CLPB_MOUSE
NC score	0.366689 (rank : 415)	θ value	2.21117e-06 (rank : 405)
Query Neighborhood Hits	1113	Target Neighborhood Hits	289	Shared Neighborhood Hits	246
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

ANKY2_HUMAN
NC score	0.365754 (rank : 416)	θ value	0.000602161 (rank : 504)
Query Neighborhood Hits	1113	Target Neighborhood Hits	306	Shared Neighborhood Hits	256
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

CTTB2_HUMAN
NC score	0.365067 (rank : 417)	θ value	5.62301e-10 (rank : 265)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1061	Shared Neighborhood Hits	318
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

ANR11_HUMAN
NC score	0.364278 (rank : 418)	θ value	1.09739e-05 (rank : 435)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1289	Shared Neighborhood Hits	364
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

HABP2_HUMAN
NC score	0.363994 (rank : 419)	θ value	1.2077e-20 (rank : 110)
Query Neighborhood Hits	1113	Target Neighborhood Hits	431	Shared Neighborhood Hits	277
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HABP2_MOUSE
NC score	0.363515 (rank : 420)	θ value	1.29031e-22 (rank : 94)
Query Neighborhood Hits	1113	Target Neighborhood Hits	445	Shared Neighborhood Hits	292
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

ANR37_HUMAN
NC score	0.362445 (rank : 421)	θ value	0.00665767 (rank : 569)
Query Neighborhood Hits	1113	Target Neighborhood Hits	247	Shared Neighborhood Hits	240
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

LYAM2_HUMAN
NC score	0.362293 (rank : 422)	θ value	3.08544e-08 (rank : 329)
Query Neighborhood Hits	1113	Target Neighborhood Hits	394	Shared Neighborhood Hits	265
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

KRA45_HUMAN
NC score	0.361837 (rank : 423)	θ value	0.000270298 (rank : 493)
Query Neighborhood Hits	1113	Target Neighborhood Hits	194	Shared Neighborhood Hits	158
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

LYAM2_MOUSE
NC score	0.360206 (rank : 424)	θ value	2.88788e-06 (rank : 414)
Query Neighborhood Hits	1113	Target Neighborhood Hits	420	Shared Neighborhood Hits	287
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

CDN2B_HUMAN
NC score	0.359733 (rank : 425)	θ value	1.43324e-05 (rank : 440)
Query Neighborhood Hits	1113	Target Neighborhood Hits	196	Shared Neighborhood Hits	193
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

NFKB2_MOUSE
NC score	0.358861 (rank : 426)	θ value	2.36244e-08 (rank : 325)
Query Neighborhood Hits	1113	Target Neighborhood Hits	326	Shared Neighborhood Hits	273
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ANR32_HUMAN
NC score	0.357898 (rank : 427)	θ value	0.0431538 (rank : 647)
Query Neighborhood Hits	1113	Target Neighborhood Hits	270	Shared Neighborhood Hits	256
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANKY2_MOUSE
NC score	0.355435 (rank : 428)	θ value	0.00020696 (rank : 482)
Query Neighborhood Hits	1113	Target Neighborhood Hits	316	Shared Neighborhood Hits	256
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

POT14_HUMAN
NC score	0.354950 (rank : 429)	θ value	0.000786445 (rank : 509)
Query Neighborhood Hits	1113	Target Neighborhood Hits	403	Shared Neighborhood Hits	270
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

ANR32_MOUSE
NC score	0.353812 (rank : 430)	θ value	0.0330416 (rank : 634)
Query Neighborhood Hits	1113	Target Neighborhood Hits	285	Shared Neighborhood Hits	254
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

KR10A_HUMAN
NC score	0.353171 (rank : 431)	θ value	2.21117e-06 (rank : 408)
Query Neighborhood Hits	1113	Target Neighborhood Hits	232	Shared Neighborhood Hits	187
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

ZAN_HUMAN
NC score	0.352422 (rank : 432)	θ value	3.19293e-05 (rank : 458)
Query Neighborhood Hits	1113	Target Neighborhood Hits	679	Shared Neighborhood Hits	350
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ANR33_HUMAN
NC score	0.352263 (rank : 433)	θ value	0.00869519 (rank : 581)
Query Neighborhood Hits	1113	Target Neighborhood Hits	215	Shared Neighborhood Hits	210
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ANR37_MOUSE
NC score	0.351102 (rank : 434)	θ value	0.00869519 (rank : 582)
Query Neighborhood Hits	1113	Target Neighborhood Hits	237	Shared Neighborhood Hits	230
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

ANR12_HUMAN
NC score	0.350938 (rank : 435)	θ value	3.41135e-07 (rank : 365)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1081	Shared Neighborhood Hits	300
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

CELR2_MOUSE
NC score	0.350766 (rank : 436)	θ value	4.74913e-17 (rank : 142)
Query Neighborhood Hits	1113	Target Neighborhood Hits	584	Shared Neighborhood Hits	325
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

KR414_HUMAN
NC score	0.350650 (rank : 437)	θ value	0.000121331 (rank : 475)
Query Neighborhood Hits	1113	Target Neighborhood Hits	199	Shared Neighborhood Hits	162
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KRA47_HUMAN
NC score	0.350316 (rank : 438)	θ value	5.81887e-07 (rank : 379)
Query Neighborhood Hits	1113	Target Neighborhood Hits	204	Shared Neighborhood Hits	162
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

TENN_HUMAN
NC score	0.350177 (rank : 439)	θ value	3.41135e-07 (rank : 372)
Query Neighborhood Hits	1113	Target Neighborhood Hits	453	Shared Neighborhood Hits	281
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

NET4_HUMAN
NC score	0.347656 (rank : 440)	θ value	2.21117e-06 (rank : 410)
Query Neighborhood Hits	1113	Target Neighborhood Hits	191	Shared Neighborhood Hits	161
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

A20A3_HUMAN
NC score	0.346527 (rank : 441)	θ value	1.63604e-09 (rank : 276)
Query Neighborhood Hits	1113	Target Neighborhood Hits	692	Shared Neighborhood Hits	278
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

KRA92_HUMAN
NC score	0.345504 (rank : 442)	θ value	4.1701e-05 (rank : 460)
Query Neighborhood Hits	1113	Target Neighborhood Hits	198	Shared Neighborhood Hits	153
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

LYAM3_HUMAN
NC score	0.345426 (rank : 443)	θ value	4.76016e-09 (rank : 298)
Query Neighborhood Hits	1113	Target Neighborhood Hits	378	Shared Neighborhood Hits	244
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

A20A1_HUMAN
NC score	0.345206 (rank : 444)	θ value	6.21693e-09 (rank : 299)
Query Neighborhood Hits	1113	Target Neighborhood Hits	698	Shared Neighborhood Hits	275
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

A20A2_HUMAN
NC score	0.344543 (rank : 445)	θ value	6.21693e-09 (rank : 300)
Query Neighborhood Hits	1113	Target Neighborhood Hits	716	Shared Neighborhood Hits	278
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

A20A4_HUMAN
NC score	0.344222 (rank : 446)	θ value	1.63604e-09 (rank : 277)
Query Neighborhood Hits	1113	Target Neighborhood Hits	710	Shared Neighborhood Hits	279
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

NFX1_HUMAN
NC score	0.343058 (rank : 447)	θ value	4.1701e-05 (rank : 461)
Query Neighborhood Hits	1113	Target Neighborhood Hits	405	Shared Neighborhood Hits	199
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

KRIT1_MOUSE
NC score	0.341178 (rank : 448)	θ value	1.09739e-05 (rank : 437)
Query Neighborhood Hits	1113	Target Neighborhood Hits	258	Shared Neighborhood Hits	223
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

POT22_HUMAN
NC score	0.341109 (rank : 449)	θ value	0.000786445 (rank : 510)
Query Neighborhood Hits	1113	Target Neighborhood Hits	266	Shared Neighborhood Hits	253
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

NET2_MOUSE
NC score	0.340960 (rank : 450)	θ value	0.00869519 (rank : 587)
Query Neighborhood Hits	1113	Target Neighborhood Hits	193	Shared Neighborhood Hits	162
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

KRIT1_HUMAN
NC score	0.340516 (rank : 451)	θ value	4.92598e-06 (rank : 423)
Query Neighborhood Hits	1113	Target Neighborhood Hits	258	Shared Neighborhood Hits	216
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

NET4_MOUSE
NC score	0.340499 (rank : 452)	θ value	0.000121331 (rank : 476)
Query Neighborhood Hits	1113	Target Neighborhood Hits	180	Shared Neighborhood Hits	158
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

KR103_HUMAN
NC score	0.339983 (rank : 453)	θ value	0.0961366 (rank : 685)
Query Neighborhood Hits	1113	Target Neighborhood Hits	212	Shared Neighborhood Hits	173
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

KRA11_HUMAN
NC score	0.339058 (rank : 454)	θ value	0.0252991 (rank : 629)
Query Neighborhood Hits	1113	Target Neighborhood Hits	155	Shared Neighborhood Hits	134
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

NET2_HUMAN
NC score	0.338645 (rank : 455)	θ value	0.0252991 (rank : 631)
Query Neighborhood Hits	1113	Target Neighborhood Hits	194	Shared Neighborhood Hits	160
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

MPP8_HUMAN
NC score	0.337785 (rank : 456)	θ value	3.77169e-06 (rank : 418)
Query Neighborhood Hits	1113	Target Neighborhood Hits	948	Shared Neighborhood Hits	276
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

OSBL1_HUMAN
NC score	0.337414 (rank : 457)	θ value	1.53129e-07 (rank : 353)
Query Neighborhood Hits	1113	Target Neighborhood Hits	368	Shared Neighborhood Hits	275
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

BCOR_MOUSE
NC score	0.336882 (rank : 458)	θ value	0.0148317 (rank : 602)
Query Neighborhood Hits	1113	Target Neighborhood Hits	521	Shared Neighborhood Hits	308
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CD2A1_HUMAN
NC score	0.336274 (rank : 459)	θ value	0.00102713 (rank : 514)
Query Neighborhood Hits	1113	Target Neighborhood Hits	196	Shared Neighborhood Hits	190
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

TDGF1_HUMAN
NC score	0.335813 (rank : 460)	θ value	0.0252991 (rank : 632)
Query Neighborhood Hits	1113	Target Neighborhood Hits	132	Shared Neighborhood Hits	130
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

KR412_HUMAN
NC score	0.335708 (rank : 461)	θ value	7.59969e-07 (rank : 384)
Query Neighborhood Hits	1113	Target Neighborhood Hits	178	Shared Neighborhood Hits	144
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

RAI14_HUMAN
NC score	0.333855 (rank : 462)	θ value	8.95645e-16 (rank : 154)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1367	Shared Neighborhood Hits	329
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

BCOR_HUMAN
NC score	0.333605 (rank : 463)	θ value	0.0148317 (rank : 601)
Query Neighborhood Hits	1113	Target Neighborhood Hits	609	Shared Neighborhood Hits	329
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

HECD1_HUMAN
NC score	0.330483 (rank : 464)	θ value	4.76016e-09 (rank : 297)
Query Neighborhood Hits	1113	Target Neighborhood Hits	371	Shared Neighborhood Hits	269
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

KRA99_HUMAN
NC score	0.330442 (rank : 465)	θ value	0.00102713 (rank : 516)
Query Neighborhood Hits	1113	Target Neighborhood Hits	173	Shared Neighborhood Hits	141
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

TDGF2_HUMAN
NC score	0.329982 (rank : 466)	θ value	0.0330416 (rank : 645)
Query Neighborhood Hits	1113	Target Neighborhood Hits	131	Shared Neighborhood Hits	126
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

OSBL1_MOUSE
NC score	0.328904 (rank : 467)	θ value	7.59969e-07 (rank : 385)
Query Neighborhood Hits	1113	Target Neighborhood Hits	336	Shared Neighborhood Hits	274
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

TEFF2_MOUSE
NC score	0.326733 (rank : 468)	θ value	4.92598e-06 (rank : 425)
Query Neighborhood Hits	1113	Target Neighborhood Hits	214	Shared Neighborhood Hits	158
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TEFF2_HUMAN
NC score	0.325707 (rank : 469)	θ value	1.69304e-06 (rank : 402)
Query Neighborhood Hits	1113	Target Neighborhood Hits	211	Shared Neighborhood Hits	156
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

ANR18_HUMAN
NC score	0.325332 (rank : 470)	θ value	1.2105e-12 (rank : 198)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1106	Shared Neighborhood Hits	295
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

LCE1B_HUMAN
NC score	0.325027 (rank : 471)	θ value	0.00869519 (rank : 586)
Query Neighborhood Hits	1113	Target Neighborhood Hits	58	Shared Neighborhood Hits	42
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

ANR40_HUMAN
NC score	0.323060 (rank : 472)	θ value	0.00228821 (rank : 537)
Query Neighborhood Hits	1113	Target Neighborhood Hits	224	Shared Neighborhood Hits	203
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

FA10_MOUSE
NC score	0.316729 (rank : 473)	θ value	3.64472e-09 (rank : 293)
Query Neighborhood Hits	1113	Target Neighborhood Hits	435	Shared Neighborhood Hits	282
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

ANR40_MOUSE
NC score	0.315956 (rank : 474)	θ value	0.00390308 (rank : 551)
Query Neighborhood Hits	1113	Target Neighborhood Hits	228	Shared Neighborhood Hits	202
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

KRA15_HUMAN
NC score	0.314524 (rank : 475)	θ value	0.0330416 (rank : 640)
Query Neighborhood Hits	1113	Target Neighborhood Hits	126	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

SNCAP_HUMAN
NC score	0.314357 (rank : 476)	θ value	2.36792 (rank : 931)
Query Neighborhood Hits	1113	Target Neighborhood Hits	313	Shared Neighborhood Hits	235
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

MUC5B_HUMAN
NC score	0.314013 (rank : 477)	θ value	0.0330416 (rank : 643)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1020	Shared Neighborhood Hits	394
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

CLPB_HUMAN
NC score	0.312404 (rank : 478)	θ value	0.0113563 (rank : 594)
Query Neighborhood Hits	1113	Target Neighborhood Hits	265	Shared Neighborhood Hits	232
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

FA10_HUMAN
NC score	0.311506 (rank : 479)	θ value	1.38499e-08 (rank : 313)
Query Neighborhood Hits	1113	Target Neighborhood Hits	431	Shared Neighborhood Hits	273
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

LCE1C_HUMAN
NC score	0.309770 (rank : 480)	θ value	0.0330416 (rank : 641)
Query Neighborhood Hits	1113	Target Neighborhood Hits	65	Shared Neighborhood Hits	46
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

RAI14_MOUSE
NC score	0.309533 (rank : 481)	θ value	7.84624e-12 (rank : 220)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1505	Shared Neighborhood Hits	337
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

VWF_HUMAN
NC score	0.307571 (rank : 482)	θ value	1.29631e-06 (rank : 399)
Query Neighborhood Hits	1113	Target Neighborhood Hits	396	Shared Neighborhood Hits	263
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ANR43_HUMAN
NC score	0.304689 (rank : 483)	θ value	0.125558 (rank : 695)
Query Neighborhood Hits	1113	Target Neighborhood Hits	209	Shared Neighborhood Hits	199
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

EMR3_HUMAN
NC score	0.302483 (rank : 484)	θ value	0.00134147 (rank : 521)
Query Neighborhood Hits	1113	Target Neighborhood Hits	245	Shared Neighborhood Hits	163
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

FA9_HUMAN
NC score	0.301929 (rank : 485)	θ value	7.34386e-10 (rank : 269)
Query Neighborhood Hits	1113	Target Neighborhood Hits	421	Shared Neighborhood Hits	270
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

AN30A_HUMAN
NC score	0.301751 (rank : 486)	θ value	1.80886e-08 (rank : 319)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1119	Shared Neighborhood Hits	302
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

LYAM1_MOUSE
NC score	0.301619 (rank : 487)	θ value	9.29e-05 (rank : 470)
Query Neighborhood Hits	1113	Target Neighborhood Hits	332	Shared Neighborhood Hits	212
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

PROC_MOUSE
NC score	0.299814 (rank : 488)	θ value	1.25267e-09 (rank : 275)
Query Neighborhood Hits	1113	Target Neighborhood Hits	426	Shared Neighborhood Hits	275
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PERT_HUMAN
NC score	0.299291 (rank : 489)	θ value	0.0193708 (rank : 622)
Query Neighborhood Hits	1113	Target Neighborhood Hits	221	Shared Neighborhood Hits	172
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

MUC13_MOUSE
NC score	0.298719 (rank : 490)	θ value	0.00665767 (rank : 576)
Query Neighborhood Hits	1113	Target Neighborhood Hits	447	Shared Neighborhood Hits	211
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

OSTF1_MOUSE
NC score	0.295745 (rank : 491)	θ value	1.38821 (rank : 873)
Query Neighborhood Hits	1113	Target Neighborhood Hits	467	Shared Neighborhood Hits	251
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

NET1_HUMAN
NC score	0.295527 (rank : 492)	θ value	0.163984 (rank : 718)
Query Neighborhood Hits	1113	Target Neighborhood Hits	149	Shared Neighborhood Hits	125
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

ASB14_HUMAN
NC score	0.295396 (rank : 493)	θ value	1.43324e-05 (rank : 439)
Query Neighborhood Hits	1113	Target Neighborhood Hits	187	Shared Neighborhood Hits	173
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

LYAM1_HUMAN
NC score	0.293970 (rank : 494)	θ value	0.000270298 (rank : 494)
Query Neighborhood Hits	1113	Target Neighborhood Hits	315	Shared Neighborhood Hits	208
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

TRPV6_MOUSE
NC score	0.293275 (rank : 495)	θ value	0.0193708 (rank : 625)
Query Neighborhood Hits	1113	Target Neighborhood Hits	284	Shared Neighborhood Hits	248
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

PGCB_MOUSE
NC score	0.293136 (rank : 496)	θ value	1.99992e-07 (rank : 359)
Query Neighborhood Hits	1113	Target Neighborhood Hits	459	Shared Neighborhood Hits	211
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

ANR43_MOUSE
NC score	0.292621 (rank : 497)	θ value	1.06291 (rank : 833)
Query Neighborhood Hits	1113	Target Neighborhood Hits	214	Shared Neighborhood Hits	201
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

NET1_MOUSE
NC score	0.291355 (rank : 498)	θ value	0.0736092 (rank : 675)
Query Neighborhood Hits	1113	Target Neighborhood Hits	151	Shared Neighborhood Hits	123
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

OSTF1_HUMAN
NC score	0.289813 (rank : 499)	θ value	0.0736092 (rank : 676)
Query Neighborhood Hits	1113	Target Neighborhood Hits	466	Shared Neighborhood Hits	250
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

ANKK1_HUMAN
NC score	0.287375 (rank : 500)	θ value	5.99374e-20 (rank : 114)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1075	Shared Neighborhood Hits	314
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

FA7_HUMAN
NC score	0.287013 (rank : 501)	θ value	3.52202e-12 (rank : 208)
Query Neighborhood Hits	1113	Target Neighborhood Hits	404	Shared Neighborhood Hits	253
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

UROL1_MOUSE
NC score	0.286992 (rank : 502)	θ value	0.00509761 (rank : 564)
Query Neighborhood Hits	1113	Target Neighborhood Hits	235	Shared Neighborhood Hits	158
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

HGFA_HUMAN
NC score	0.283392 (rank : 503)	θ value	3.18553e-13 (rank : 189)
Query Neighborhood Hits	1113	Target Neighborhood Hits	436	Shared Neighborhood Hits	252
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

IASPP_HUMAN
NC score	0.280842 (rank : 504)	θ value	0.0431538 (rank : 648)
Query Neighborhood Hits	1113	Target Neighborhood Hits	688	Shared Neighborhood Hits	321
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

CRAC1_MOUSE
NC score	0.280650 (rank : 505)	θ value	θ > 10 (rank : 1151)
Query Neighborhood Hits	1113	Target Neighborhood Hits	112	Shared Neighborhood Hits	97
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

PERT_MOUSE
NC score	0.279270 (rank : 506)	θ value	0.00102713 (rank : 517)
Query Neighborhood Hits	1113	Target Neighborhood Hits	221	Shared Neighborhood Hits	165
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

HGFA_MOUSE
NC score	0.279267 (rank : 507)	θ value	9.26847e-13 (rank : 196)
Query Neighborhood Hits	1113	Target Neighborhood Hits	419	Shared Neighborhood Hits	254
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

ANKK1_MOUSE
NC score	0.278912 (rank : 508)	θ value	7.32683e-18 (rank : 137)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1072	Shared Neighborhood Hits	313
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

CRAC1_HUMAN
NC score	0.278577 (rank : 509)	θ value	θ > 10 (rank : 1150)
Query Neighborhood Hits	1113	Target Neighborhood Hits	111	Shared Neighborhood Hits	96
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

VWF_MOUSE
NC score	0.278137 (rank : 510)	θ value	1.29631e-06 (rank : 400)
Query Neighborhood Hits	1113	Target Neighborhood Hits	381	Shared Neighborhood Hits	247
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

NRX1A_HUMAN
NC score	0.276613 (rank : 511)	θ value	0.00175202 (rank : 531)
Query Neighborhood Hits	1113	Target Neighborhood Hits	170	Shared Neighborhood Hits	138
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

LCE1D_HUMAN
NC score	0.276399 (rank : 512)	θ value	1.06291 (rank : 844)
Query Neighborhood Hits	1113	Target Neighborhood Hits	44	Shared Neighborhood Hits	32
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

FAT2_HUMAN
NC score	0.276315 (rank : 513)	θ value	7.58209e-15 (rank : 161)
Query Neighborhood Hits	1113	Target Neighborhood Hits	507	Shared Neighborhood Hits	276
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

NRX1A_MOUSE
NC score	0.275751 (rank : 514)	θ value	0.00134147 (rank : 524)
Query Neighborhood Hits	1113	Target Neighborhood Hits	164	Shared Neighborhood Hits	137
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

RIPK4_HUMAN
NC score	0.275622 (rank : 515)	θ value	6.41864e-14 (rank : 182)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1094	Shared Neighborhood Hits	320
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

PGCB_HUMAN
NC score	0.274094 (rank : 516)	θ value	2.21117e-06 (rank : 411)
Query Neighborhood Hits	1113	Target Neighborhood Hits	478	Shared Neighborhood Hits	212
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

ABTB2_HUMAN
NC score	0.272926 (rank : 517)	θ value	0.0252991 (rank : 627)
Query Neighborhood Hits	1113	Target Neighborhood Hits	391	Shared Neighborhood Hits	233
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

CENB1_HUMAN
NC score	0.272045 (rank : 518)	θ value	0.00665767 (rank : 574)
Query Neighborhood Hits	1113	Target Neighborhood Hits	383	Shared Neighborhood Hits	256
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CENB5_HUMAN
NC score	0.270620 (rank : 519)	θ value	0.00035302 (rank : 499)
Query Neighborhood Hits	1113	Target Neighborhood Hits	395	Shared Neighborhood Hits	262
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

PROC_HUMAN
NC score	0.270555 (rank : 520)	θ value	1.17247e-07 (rank : 350)
Query Neighborhood Hits	1113	Target Neighborhood Hits	406	Shared Neighborhood Hits	259
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

UACA_HUMAN
NC score	0.268634 (rank : 521)	θ value	2.0648e-12 (rank : 206)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1622	Shared Neighborhood Hits	327
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

LCE1E_HUMAN
NC score	0.267707 (rank : 522)	θ value	0.0252991 (rank : 630)
Query Neighborhood Hits	1113	Target Neighborhood Hits	53	Shared Neighborhood Hits	35
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

UROL1_HUMAN
NC score	0.267122 (rank : 523)	θ value	0.125558 (rank : 705)
Query Neighborhood Hits	1113	Target Neighborhood Hits	213	Shared Neighborhood Hits	145
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

TRPV5_MOUSE
NC score	0.266736 (rank : 524)	θ value	0.00175202 (rank : 533)
Query Neighborhood Hits	1113	Target Neighborhood Hits	278	Shared Neighborhood Hits	243
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

ABTB2_MOUSE
NC score	0.266144 (rank : 525)	θ value	0.0113563 (rank : 592)
Query Neighborhood Hits	1113	Target Neighborhood Hits	414	Shared Neighborhood Hits	234
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

TRPV5_HUMAN
NC score	0.264469 (rank : 526)	θ value	0.000786445 (rank : 511)
Query Neighborhood Hits	1113	Target Neighborhood Hits	261	Shared Neighborhood Hits	219
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

ASPP2_HUMAN
NC score	0.264158 (rank : 527)	θ value	0.0113563 (rank : 593)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1156	Shared Neighborhood Hits	338
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

NRX2A_HUMAN
NC score	0.263181 (rank : 528)	θ value	0.00298849 (rank : 548)
Query Neighborhood Hits	1113	Target Neighborhood Hits	614	Shared Neighborhood Hits	263
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

GIT2_MOUSE
NC score	0.263047 (rank : 529)	θ value	1.29631e-06 (rank : 397)
Query Neighborhood Hits	1113	Target Neighborhood Hits	323	Shared Neighborhood Hits	249
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

GIT1_MOUSE
NC score	0.262510 (rank : 530)	θ value	2.88788e-06 (rank : 412)
Query Neighborhood Hits	1113	Target Neighborhood Hits	341	Shared Neighborhood Hits	243
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

NRX3A_HUMAN
NC score	0.261363 (rank : 531)	θ value	0.0148317 (rank : 610)
Query Neighborhood Hits	1113	Target Neighborhood Hits	164	Shared Neighborhood Hits	144
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

GIT1_HUMAN
NC score	0.260355 (rank : 532)	θ value	2.44474e-05 (rank : 449)
Query Neighborhood Hits	1113	Target Neighborhood Hits	336	Shared Neighborhood Hits	242
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

MMRN1_HUMAN
NC score	0.260020 (rank : 533)	θ value	4.92598e-06 (rank : 424)
Query Neighborhood Hits	1113	Target Neighborhood Hits	636	Shared Neighborhood Hits	191
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

FA12_HUMAN
NC score	0.259938 (rank : 534)	θ value	9.59137e-10 (rank : 272)
Query Neighborhood Hits	1113	Target Neighborhood Hits	425	Shared Neighborhood Hits	248
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

CENB2_HUMAN
NC score	0.259544 (rank : 535)	θ value	0.0148317 (rank : 604)
Query Neighborhood Hits	1113	Target Neighborhood Hits	425	Shared Neighborhood Hits	249
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

KR410_HUMAN
NC score	0.259334 (rank : 536)	θ value	0.21417 (rank : 726)
Query Neighborhood Hits	1113	Target Neighborhood Hits	156	Shared Neighborhood Hits	131
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

CLC14_MOUSE
NC score	0.259233 (rank : 537)	θ value	1.06291 (rank : 837)
Query Neighborhood Hits	1113	Target Neighborhood Hits	120	Shared Neighborhood Hits	111
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

ILK2_HUMAN
NC score	0.258642 (rank : 538)	θ value	9.92553e-07 (rank : 392)
Query Neighborhood Hits	1113	Target Neighborhood Hits	848	Shared Neighborhood Hits	300
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

UACA_MOUSE
NC score	0.258029 (rank : 539)	θ value	1.2105e-12 (rank : 201)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1620	Shared Neighborhood Hits	329
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

KRA42_HUMAN
NC score	0.257542 (rank : 540)	θ value	0.00175202 (rank : 529)
Query Neighborhood Hits	1113	Target Neighborhood Hits	149	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

CNTP2_MOUSE
NC score	0.257353 (rank : 541)	θ value	0.00175202 (rank : 528)
Query Neighborhood Hits	1113	Target Neighborhood Hits	194	Shared Neighborhood Hits	147
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

TRPV6_HUMAN
NC score	0.257307 (rank : 542)	θ value	0.00665767 (rank : 579)
Query Neighborhood Hits	1113	Target Neighborhood Hits	262	Shared Neighborhood Hits	221
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

ASPP1_HUMAN
NC score	0.256804 (rank : 543)	θ value	0.00665767 (rank : 572)
Query Neighborhood Hits	1113	Target Neighborhood Hits	956	Shared Neighborhood Hits	304
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

LRP6_HUMAN
NC score	0.256774 (rank : 544)	θ value	0.0961366 (rank : 686)
Query Neighborhood Hits	1113	Target Neighborhood Hits	235	Shared Neighborhood Hits	177
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

IASPP_MOUSE
NC score	0.256670 (rank : 545)	θ value	0.0330416 (rank : 639)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1024	Shared Neighborhood Hits	391
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ASPP1_MOUSE
NC score	0.256088 (rank : 546)	θ value	0.00665767 (rank : 573)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1244	Shared Neighborhood Hits	384
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CNTP2_HUMAN
NC score	0.254727 (rank : 547)	θ value	0.00175202 (rank : 527)
Query Neighborhood Hits	1113	Target Neighborhood Hits	199	Shared Neighborhood Hits	151
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

ANKY1_HUMAN
NC score	0.254229 (rank : 548)	θ value	0.813845 (rank : 813)
Query Neighborhood Hits	1113	Target Neighborhood Hits	248	Shared Neighborhood Hits	201
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

LRP6_MOUSE
NC score	0.252594 (rank : 549)	θ value	0.0563607 (rank : 665)
Query Neighborhood Hits	1113	Target Neighborhood Hits	232	Shared Neighborhood Hits	173
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

BMP1_MOUSE
NC score	0.252312 (rank : 550)	θ value	0.0563607 (rank : 659)
Query Neighborhood Hits	1113	Target Neighborhood Hits	236	Shared Neighborhood Hits	184
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

ANR45_MOUSE
NC score	0.252309 (rank : 551)	θ value	θ > 10 (rank : 1123)
Query Neighborhood Hits	1113	Target Neighborhood Hits	204	Shared Neighborhood Hits	183
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

TLL1_MOUSE
NC score	0.250579 (rank : 552)	θ value	0.0961366 (rank : 693)
Query Neighborhood Hits	1113	Target Neighborhood Hits	237	Shared Neighborhood Hits	182
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

BMP1_HUMAN
NC score	0.250440 (rank : 553)	θ value	0.0563607 (rank : 658)
Query Neighborhood Hits	1113	Target Neighborhood Hits	233	Shared Neighborhood Hits	183
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

FA7_MOUSE
NC score	0.250291 (rank : 554)	θ value	2.13673e-09 (rank : 283)
Query Neighborhood Hits	1113	Target Neighborhood Hits	374	Shared Neighborhood Hits	228
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

ILK1_HUMAN
NC score	0.249588 (rank : 555)	θ value	9.92553e-07 (rank : 391)
Query Neighborhood Hits	1113	Target Neighborhood Hits	857	Shared Neighborhood Hits	300
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ANR26_MOUSE
NC score	0.248673 (rank : 556)	θ value	1.74796e-11 (rank : 224)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1554	Shared Neighborhood Hits	334
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ILK_MOUSE
NC score	0.248475 (rank : 557)	θ value	5.81887e-07 (rank : 378)
Query Neighborhood Hits	1113	Target Neighborhood Hits	858	Shared Neighborhood Hits	299
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

LCE1F_HUMAN
NC score	0.248149 (rank : 558)	θ value	0.0113563 (rank : 598)
Query Neighborhood Hits	1113	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

NUD12_MOUSE
NC score	0.248129 (rank : 559)	θ value	θ > 10 (rank : 1263)
Query Neighborhood Hits	1113	Target Neighborhood Hits	243	Shared Neighborhood Hits	215
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

CNTP4_MOUSE
NC score	0.247585 (rank : 560)	θ value	0.00020696 (rank : 487)
Query Neighborhood Hits	1113	Target Neighborhood Hits	193	Shared Neighborhood Hits	147
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

AN13B_MOUSE
NC score	0.246722 (rank : 561)	θ value	0.47712 (rank : 773)
Query Neighborhood Hits	1113	Target Neighborhood Hits	276	Shared Neighborhood Hits	248
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

MFGM_HUMAN
NC score	0.246658 (rank : 562)	θ value	0.000270298 (rank : 495)
Query Neighborhood Hits	1113	Target Neighborhood Hits	150	Shared Neighborhood Hits	129
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

TLL2_HUMAN
NC score	0.245586 (rank : 563)	θ value	0.0113563 (rank : 600)
Query Neighborhood Hits	1113	Target Neighborhood Hits	241	Shared Neighborhood Hits	184
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

AN13B_HUMAN
NC score	0.244770 (rank : 564)	θ value	0.47712 (rank : 772)
Query Neighborhood Hits	1113	Target Neighborhood Hits	265	Shared Neighborhood Hits	248
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

LRP5_MOUSE
NC score	0.243961 (rank : 565)	θ value	1.81305 (rank : 893)
Query Neighborhood Hits	1113	Target Neighborhood Hits	236	Shared Neighborhood Hits	172
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

TLL1_HUMAN
NC score	0.243539 (rank : 566)	θ value	0.125558 (rank : 702)
Query Neighborhood Hits	1113	Target Neighborhood Hits	236	Shared Neighborhood Hits	178
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

CLC14_HUMAN
NC score	0.243272 (rank : 567)	θ value	4.03905 (rank : 982)
Query Neighborhood Hits	1113	Target Neighborhood Hits	143	Shared Neighborhood Hits	119
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

LCE1A_HUMAN
NC score	0.241133 (rank : 568)	θ value	0.125558 (rank : 699)
Query Neighborhood Hits	1113	Target Neighborhood Hits	47	Shared Neighborhood Hits	34
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

CNTP4_HUMAN
NC score	0.239824 (rank : 569)	θ value	0.00298849 (rank : 545)
Query Neighborhood Hits	1113	Target Neighborhood Hits	187	Shared Neighborhood Hits	129
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

ANR45_HUMAN
NC score	0.239199 (rank : 570)	θ value	θ > 10 (rank : 1122)
Query Neighborhood Hits	1113	Target Neighborhood Hits	201	Shared Neighborhood Hits	178
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

RELN_MOUSE
NC score	0.237708 (rank : 571)	θ value	0.21417 (rank : 731)
Query Neighborhood Hits	1113	Target Neighborhood Hits	235	Shared Neighborhood Hits	194
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

TLL2_MOUSE
NC score	0.236951 (rank : 572)	θ value	0.125558 (rank : 703)
Query Neighborhood Hits	1113	Target Neighborhood Hits	240	Shared Neighborhood Hits	182
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

CNTP3_HUMAN
NC score	0.236727 (rank : 573)	θ value	0.000158464 (rank : 479)
Query Neighborhood Hits	1113	Target Neighborhood Hits	195	Shared Neighborhood Hits	136
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

LRP5_HUMAN
NC score	0.235947 (rank : 574)	θ value	3.0926 (rank : 957)
Query Neighborhood Hits	1113	Target Neighborhood Hits	224	Shared Neighborhood Hits	168
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

SMDF_HUMAN
NC score	0.232648 (rank : 575)	θ value	0.0148317 (rank : 612)
Query Neighborhood Hits	1113	Target Neighborhood Hits	117	Shared Neighborhood Hits	92
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

NRG4_HUMAN
NC score	0.232234 (rank : 576)	θ value	0.0148317 (rank : 609)
Query Neighborhood Hits	1113	Target Neighborhood Hits	85	Shared Neighborhood Hits	81
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

MEP1A_MOUSE
NC score	0.231491 (rank : 577)	θ value	2.44474e-05 (rank : 452)
Query Neighborhood Hits	1113	Target Neighborhood Hits	166	Shared Neighborhood Hits	136
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

RECK_HUMAN
NC score	0.230942 (rank : 578)	θ value	0.0563607 (rank : 666)
Query Neighborhood Hits	1113	Target Neighborhood Hits	189	Shared Neighborhood Hits	127
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

ANR26_HUMAN
NC score	0.230819 (rank : 579)	θ value	1.06045e-08 (rank : 308)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1614	Shared Neighborhood Hits	328
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

GIT2_HUMAN
NC score	0.229715 (rank : 580)	θ value	3.0926 (rank : 952)
Query Neighborhood Hits	1113	Target Neighborhood Hits	381	Shared Neighborhood Hits	242
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

RELN_HUMAN
NC score	0.228042 (rank : 581)	θ value	0.365318 (rank : 765)
Query Neighborhood Hits	1113	Target Neighborhood Hits	233	Shared Neighborhood Hits	191
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

PGH2_MOUSE
NC score	0.227531 (rank : 582)	θ value	0.00869519 (rank : 589)
Query Neighborhood Hits	1113	Target Neighborhood Hits	113	Shared Neighborhood Hits	104
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

NUD12_HUMAN
NC score	0.227142 (rank : 583)	θ value	θ > 10 (rank : 1262)
Query Neighborhood Hits	1113	Target Neighborhood Hits	222	Shared Neighborhood Hits	193
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

GLSK_HUMAN
NC score	0.227005 (rank : 584)	θ value	9.29e-05 (rank : 468)
Query Neighborhood Hits	1113	Target Neighborhood Hits	204	Shared Neighborhood Hits	182
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

AN13C_HUMAN
NC score	0.226502 (rank : 585)	θ value	4.03905 (rank : 980)
Query Neighborhood Hits	1113	Target Neighborhood Hits	241	Shared Neighborhood Hits	232
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

NRG4_MOUSE
NC score	0.225921 (rank : 586)	θ value	0.0193708 (rank : 621)
Query Neighborhood Hits	1113	Target Neighborhood Hits	79	Shared Neighborhood Hits	74
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

MEP1A_HUMAN
NC score	0.225369 (rank : 587)	θ value	1.43324e-05 (rank : 444)
Query Neighborhood Hits	1113	Target Neighborhood Hits	162	Shared Neighborhood Hits	138
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

CT012_MOUSE
NC score	0.224364 (rank : 588)	θ value	0.0736092 (rank : 672)
Query Neighborhood Hits	1113	Target Neighborhood Hits	229	Shared Neighborhood Hits	192
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

GLSL_HUMAN
NC score	0.222700 (rank : 589)	θ value	θ > 10 (rank : 1173)
Query Neighborhood Hits	1113	Target Neighborhood Hits	211	Shared Neighborhood Hits	195
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

EMR4_MOUSE
NC score	0.221859 (rank : 590)	θ value	0.00509761 (rank : 560)
Query Neighborhood Hits	1113	Target Neighborhood Hits	191	Shared Neighborhood Hits	121
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

NRG1_HUMAN
NC score	0.221129 (rank : 591)	θ value	0.000786445 (rank : 508)
Query Neighborhood Hits	1113	Target Neighborhood Hits	285	Shared Neighborhood Hits	113
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

ADAM8_MOUSE
NC score	0.221084 (rank : 592)	θ value	6.43352e-06 (rank : 426)
Query Neighborhood Hits	1113	Target Neighborhood Hits	326	Shared Neighborhood Hits	230
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

AN13C_MOUSE
NC score	0.220880 (rank : 593)	θ value	5.27518 (rank : 1015)
Query Neighborhood Hits	1113	Target Neighborhood Hits	242	Shared Neighborhood Hits	230
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

NRG2_MOUSE
NC score	0.220176 (rank : 594)	θ value	2.44474e-05 (rank : 453)
Query Neighborhood Hits	1113	Target Neighborhood Hits	392	Shared Neighborhood Hits	140
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

DDFL1_MOUSE
NC score	0.219565 (rank : 595)	θ value	0.0961366 (rank : 682)
Query Neighborhood Hits	1113	Target Neighborhood Hits	324	Shared Neighborhood Hits	242
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

PCSK5_HUMAN
NC score	0.219395 (rank : 596)	θ value	5.27518 (rank : 1044)
Query Neighborhood Hits	1113	Target Neighborhood Hits	291	Shared Neighborhood Hits	193
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

GLSL_MOUSE
NC score	0.219182 (rank : 597)	θ value	θ > 10 (rank : 1174)
Query Neighborhood Hits	1113	Target Neighborhood Hits	212	Shared Neighborhood Hits	195
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

CNTP1_HUMAN
NC score	0.218567 (rank : 598)	θ value	0.163984 (rank : 713)
Query Neighborhood Hits	1113	Target Neighborhood Hits	196	Shared Neighborhood Hits	135
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

PGCA_HUMAN
NC score	0.218550 (rank : 599)	θ value	9.29e-05 (rank : 471)
Query Neighborhood Hits	1113	Target Neighborhood Hits	821	Shared Neighborhood Hits	233
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

ADA11_HUMAN
NC score	0.217778 (rank : 600)	θ value	7.34386e-10 (rank : 267)
Query Neighborhood Hits	1113	Target Neighborhood Hits	259	Shared Neighborhood Hits	198
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

CO7_HUMAN
NC score	0.217643 (rank : 601)	θ value	6.43352e-06 (rank : 429)
Query Neighborhood Hits	1113	Target Neighborhood Hits	278	Shared Neighborhood Hits	153
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO6_HUMAN
NC score	0.217507 (rank : 602)	θ value	9.92553e-07 (rank : 389)
Query Neighborhood Hits	1113	Target Neighborhood Hits	331	Shared Neighborhood Hits	188
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

AN13A_HUMAN
NC score	0.216980 (rank : 603)	θ value	0.21417 (rank : 720)
Query Neighborhood Hits	1113	Target Neighborhood Hits	243	Shared Neighborhood Hits	212
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

TIE1_HUMAN
NC score	0.216474 (rank : 604)	θ value	7.84624e-12 (rank : 221)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1241	Shared Neighborhood Hits	340
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

ADA11_MOUSE
NC score	0.216458 (rank : 605)	θ value	2.13673e-09 (rank : 280)
Query Neighborhood Hits	1113	Target Neighborhood Hits	263	Shared Neighborhood Hits	201
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

CORIN_HUMAN
NC score	0.215128 (rank : 606)	θ value	3.89403e-11 (rank : 230)
Query Neighborhood Hits	1113	Target Neighborhood Hits	453	Shared Neighborhood Hits	240
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

TECTA_MOUSE
NC score	0.215035 (rank : 607)	θ value	0.21417 (rank : 735)
Query Neighborhood Hits	1113	Target Neighborhood Hits	244	Shared Neighborhood Hits	201
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

PGH2_HUMAN
NC score	0.214426 (rank : 608)	θ value	0.000158464 (rank : 481)
Query Neighborhood Hits	1113	Target Neighborhood Hits	103	Shared Neighborhood Hits	93
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

TNI3K_HUMAN
NC score	0.213788 (rank : 609)	θ value	1.38499e-08 (rank : 318)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1084	Shared Neighborhood Hits	316
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

TIE1_MOUSE
NC score	0.212769 (rank : 610)	θ value	5.08577e-11 (rank : 237)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1266	Shared Neighborhood Hits	336
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

CNTP1_MOUSE
NC score	0.210877 (rank : 611)	θ value	0.163984 (rank : 714)
Query Neighborhood Hits	1113	Target Neighborhood Hits	183	Shared Neighborhood Hits	127
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

TNI3K_MOUSE
NC score	0.210737 (rank : 612)	θ value	2.79066e-09 (rank : 291)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1079	Shared Neighborhood Hits	315
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

KR413_HUMAN
NC score	0.209661 (rank : 613)	θ value	0.62314 (rank : 799)
Query Neighborhood Hits	1113	Target Neighborhood Hits	112	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

MUC2_HUMAN
NC score	0.206375 (rank : 614)	θ value	0.00509761 (rank : 561)
Query Neighborhood Hits	1113	Target Neighborhood Hits	906	Shared Neighborhood Hits	273
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

ADA23_HUMAN
NC score	0.204933 (rank : 615)	θ value	0.00134147 (rank : 519)
Query Neighborhood Hits	1113	Target Neighborhood Hits	235	Shared Neighborhood Hits	189
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

MATN1_HUMAN
NC score	0.204590 (rank : 616)	θ value	0.365318 (rank : 761)
Query Neighborhood Hits	1113	Target Neighborhood Hits	191	Shared Neighborhood Hits	144
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

BMPER_MOUSE
NC score	0.203865 (rank : 617)	θ value	0.47712 (rank : 775)
Query Neighborhood Hits	1113	Target Neighborhood Hits	194	Shared Neighborhood Hits	147
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

ADAM8_HUMAN
NC score	0.203025 (rank : 618)	θ value	0.00102713 (rank : 512)
Query Neighborhood Hits	1113	Target Neighborhood Hits	327	Shared Neighborhood Hits	247
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

AN13A_MOUSE
NC score	0.202564 (rank : 619)	θ value	1.38821 (rank : 858)
Query Neighborhood Hits	1113	Target Neighborhood Hits	226	Shared Neighborhood Hits	211
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

MATN1_MOUSE
NC score	0.202522 (rank : 620)	θ value	2.36792 (rank : 921)
Query Neighborhood Hits	1113	Target Neighborhood Hits	186	Shared Neighborhood Hits	140
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

PGH1_MOUSE
NC score	0.201726 (rank : 621)	θ value	0.00134147 (rank : 525)
Query Neighborhood Hits	1113	Target Neighborhood Hits	100	Shared Neighborhood Hits	85
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

DAPK1_MOUSE
NC score	0.200113 (rank : 622)	θ value	6.62687e-19 (rank : 125)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1138	Shared Neighborhood Hits	315
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

ADA15_MOUSE
NC score	0.199896 (rank : 623)	θ value	0.163984 (rank : 707)
Query Neighborhood Hits	1113	Target Neighborhood Hits	324	Shared Neighborhood Hits	236
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADA23_MOUSE
NC score	0.198578 (rank : 624)	θ value	0.00298849 (rank : 542)
Query Neighborhood Hits	1113	Target Neighborhood Hits	245	Shared Neighborhood Hits	203
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ESM1_HUMAN
NC score	0.196676 (rank : 625)	θ value	0.365318 (rank : 755)
Query Neighborhood Hits	1113	Target Neighborhood Hits	110	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

DAPK1_HUMAN
NC score	0.195873 (rank : 626)	θ value	5.07402e-19 (rank : 123)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1130	Shared Neighborhood Hits	313
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

CO8B_MOUSE
NC score	0.195219 (rank : 627)	θ value	0.00102713 (rank : 515)
Query Neighborhood Hits	1113	Target Neighborhood Hits	224	Shared Neighborhood Hits	133
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CT012_HUMAN
NC score	0.195020 (rank : 628)	θ value	3.0926 (rank : 947)
Query Neighborhood Hits	1113	Target Neighborhood Hits	205	Shared Neighborhood Hits	179
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

TEX14_HUMAN
NC score	0.193899 (rank : 629)	θ value	0.00665767 (rank : 578)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1103	Shared Neighborhood Hits	294
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

DDEF2_HUMAN
NC score	0.193409 (rank : 630)	θ value	0.0563607 (rank : 661)
Query Neighborhood Hits	1113	Target Neighborhood Hits	599	Shared Neighborhood Hits	260
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

APR3_MOUSE
NC score	0.193087 (rank : 631)	θ value	0.21417 (rank : 721)
Query Neighborhood Hits	1113	Target Neighborhood Hits	61	Shared Neighborhood Hits	59
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

TECTA_HUMAN
NC score	0.192563 (rank : 632)	θ value	2.36792 (rank : 934)
Query Neighborhood Hits	1113	Target Neighborhood Hits	239	Shared Neighborhood Hits	192
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

DDEF2_MOUSE
NC score	0.192379 (rank : 633)	θ value	0.0563607 (rank : 662)
Query Neighborhood Hits	1113	Target Neighborhood Hits	625	Shared Neighborhood Hits	266
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

MUC13_HUMAN
NC score	0.192107 (rank : 634)	θ value	0.62314 (rank : 802)
Query Neighborhood Hits	1113	Target Neighborhood Hits	164	Shared Neighborhood Hits	106
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

CORIN_MOUSE
NC score	0.191466 (rank : 635)	θ value	8.97725e-08 (rank : 345)
Query Neighborhood Hits	1113	Target Neighborhood Hits	451	Shared Neighborhood Hits	228
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

TEX14_MOUSE
NC score	0.191466 (rank : 636)	θ value	0.00175202 (rank : 532)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1333	Shared Neighborhood Hits	305
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

RECK_MOUSE
NC score	0.189913 (rank : 637)	θ value	0.0431538 (rank : 654)
Query Neighborhood Hits	1113	Target Neighborhood Hits	158	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

ADA19_MOUSE
NC score	0.189827 (rank : 638)	θ value	0.00390308 (rank : 550)
Query Neighborhood Hits	1113	Target Neighborhood Hits	315	Shared Neighborhood Hits	217
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ADA19_HUMAN
NC score	0.189506 (rank : 639)	θ value	0.000158464 (rank : 477)
Query Neighborhood Hits	1113	Target Neighborhood Hits	381	Shared Neighborhood Hits	232
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

BMPER_HUMAN
NC score	0.189352 (rank : 640)	θ value	1.06291 (rank : 835)
Query Neighborhood Hits	1113	Target Neighborhood Hits	175	Shared Neighborhood Hits	133
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

NRG2_HUMAN
NC score	0.188060 (rank : 641)	θ value	7.1131e-05 (rank : 466)
Query Neighborhood Hits	1113	Target Neighborhood Hits	419	Shared Neighborhood Hits	138
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

TIE2_HUMAN
NC score	0.187826 (rank : 642)	θ value	4.30538e-10 (rank : 263)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1192	Shared Neighborhood Hits	306
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TIE2_MOUSE
NC score	0.186830 (rank : 643)	θ value	1.133e-10 (rank : 248)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1204	Shared Neighborhood Hits	313
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

PCSK6_HUMAN
NC score	0.186060 (rank : 644)	θ value	0.21417 (rank : 730)
Query Neighborhood Hits	1113	Target Neighborhood Hits	298	Shared Neighborhood Hits	161
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

CENG1_HUMAN
NC score	0.185416 (rank : 645)	θ value	0.00509761 (rank : 558)
Query Neighborhood Hits	1113	Target Neighborhood Hits	544	Shared Neighborhood Hits	263
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

LCE3A_HUMAN
NC score	0.185296 (rank : 646)	θ value	θ > 10 (rank : 1227)
Query Neighborhood Hits	1113	Target Neighborhood Hits	29	Shared Neighborhood Hits	26
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

ADA15_HUMAN
NC score	0.184541 (rank : 647)	θ value	0.00665767 (rank : 566)
Query Neighborhood Hits	1113	Target Neighborhood Hits	288	Shared Neighborhood Hits	221
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

KRA24_HUMAN
NC score	0.183855 (rank : 648)	θ value	8.99809 (rank : 1092)
Query Neighborhood Hits	1113	Target Neighborhood Hits	192	Shared Neighborhood Hits	140
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

CENG1_MOUSE
NC score	0.182355 (rank : 649)	θ value	0.00509761 (rank : 559)
Query Neighborhood Hits	1113	Target Neighborhood Hits	531	Shared Neighborhood Hits	261
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

ADAM9_MOUSE
NC score	0.182040 (rank : 650)	θ value	0.00228821 (rank : 536)
Query Neighborhood Hits	1113	Target Neighborhood Hits	325	Shared Neighborhood Hits	217
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

PHXR5_MOUSE
NC score	0.180269 (rank : 651)	θ value	θ > 10 (rank : 1266)
Query Neighborhood Hits	1113	Target Neighborhood Hits	102	Shared Neighborhood Hits	79
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

FSTL3_HUMAN
NC score	0.179504 (rank : 652)	θ value	0.813845 (rank : 817)
Query Neighborhood Hits	1113	Target Neighborhood Hits	162	Shared Neighborhood Hits	106
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

ADA18_MOUSE
NC score	0.177861 (rank : 653)	θ value	0.00390308 (rank : 549)
Query Neighborhood Hits	1113	Target Neighborhood Hits	227	Shared Neighborhood Hits	190
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ADA33_HUMAN
NC score	0.177797 (rank : 654)	θ value	0.0330416 (rank : 633)
Query Neighborhood Hits	1113	Target Neighborhood Hits	264	Shared Neighborhood Hits	197
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

PGH1_HUMAN
NC score	0.175904 (rank : 655)	θ value	0.00869519 (rank : 588)
Query Neighborhood Hits	1113	Target Neighborhood Hits	91	Shared Neighborhood Hits	78
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

ANKZ1_MOUSE
NC score	0.175899 (rank : 656)	θ value	0.47712 (rank : 774)
Query Neighborhood Hits	1113	Target Neighborhood Hits	208	Shared Neighborhood Hits	150
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

LRP3_HUMAN
NC score	0.175503 (rank : 657)	θ value	1.06291 (rank : 846)
Query Neighborhood Hits	1113	Target Neighborhood Hits	280	Shared Neighborhood Hits	163
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

DGKZ_HUMAN
NC score	0.175252 (rank : 658)	θ value	8.99809 (rank : 1084)
Query Neighborhood Hits	1113	Target Neighborhood Hits	551	Shared Neighborhood Hits	214
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

APR3_HUMAN
NC score	0.174465 (rank : 659)	θ value	1.38821 (rank : 859)
Query Neighborhood Hits	1113	Target Neighborhood Hits	50	Shared Neighborhood Hits	49
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

ADA33_MOUSE
NC score	0.174084 (rank : 660)	θ value	1.87187e-05 (rank : 446)
Query Neighborhood Hits	1113	Target Neighborhood Hits	231	Shared Neighborhood Hits	181
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ANKZ1_HUMAN
NC score	0.172404 (rank : 661)	θ value	0.365318 (rank : 751)
Query Neighborhood Hits	1113	Target Neighborhood Hits	236	Shared Neighborhood Hits	156
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

TPA_MOUSE
NC score	0.172358 (rank : 662)	θ value	5.81887e-07 (rank : 380)
Query Neighborhood Hits	1113	Target Neighborhood Hits	335	Shared Neighborhood Hits	186
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

ADAM9_HUMAN
NC score	0.171740 (rank : 663)	θ value	0.00298849 (rank : 543)
Query Neighborhood Hits	1113	Target Neighborhood Hits	243	Shared Neighborhood Hits	186
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

TPA_HUMAN
NC score	0.171650 (rank : 664)	θ value	2.44474e-05 (rank : 454)
Query Neighborhood Hits	1113	Target Neighborhood Hits	324	Shared Neighborhood Hits	175
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

EREG_HUMAN
NC score	0.171585 (rank : 665)	θ value	0.62314 (rank : 796)
Query Neighborhood Hits	1113	Target Neighborhood Hits	73	Shared Neighborhood Hits	67
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

MT3_MOUSE
NC score	0.171200 (rank : 666)	θ value	θ > 10 (rank : 1250)
Query Neighborhood Hits	1113	Target Neighborhood Hits	68	Shared Neighborhood Hits	57
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

DDFL1_HUMAN
NC score	0.171076 (rank : 667)	θ value	4.03905 (rank : 985)
Query Neighborhood Hits	1113	Target Neighborhood Hits	353	Shared Neighborhood Hits	229
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

IKBL_HUMAN
NC score	0.170831 (rank : 668)	θ value	1.81305 (rank : 891)
Query Neighborhood Hits	1113	Target Neighborhood Hits	168	Shared Neighborhood Hits	139
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

CENG3_HUMAN
NC score	0.170768 (rank : 669)	θ value	0.000270298 (rank : 490)
Query Neighborhood Hits	1113	Target Neighborhood Hits	455	Shared Neighborhood Hits	228
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

C1RA_MOUSE
NC score	0.170669 (rank : 670)	θ value	0.00020696 (rank : 485)
Query Neighborhood Hits	1113	Target Neighborhood Hits	379	Shared Neighborhood Hits	178
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

CENG3_MOUSE
NC score	0.170525 (rank : 671)	θ value	0.000270298 (rank : 491)
Query Neighborhood Hits	1113	Target Neighborhood Hits	467	Shared Neighborhood Hits	229
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

ADA22_MOUSE
NC score	0.170214 (rank : 672)	θ value	8.40245e-06 (rank : 431)
Query Neighborhood Hits	1113	Target Neighborhood Hits	225	Shared Neighborhood Hits	164
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

FSTL3_MOUSE
NC score	0.169789 (rank : 673)	θ value	0.47712 (rank : 780)
Query Neighborhood Hits	1113	Target Neighborhood Hits	152	Shared Neighborhood Hits	101
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

MT4_MOUSE
NC score	0.169737 (rank : 674)	θ value	5.27518 (rank : 1040)
Query Neighborhood Hits	1113	Target Neighborhood Hits	102	Shared Neighborhood Hits	79
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

ADAM2_MOUSE
NC score	0.169554 (rank : 675)	θ value	0.000602161 (rank : 503)
Query Neighborhood Hits	1113	Target Neighborhood Hits	209	Shared Neighborhood Hits	166
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

ST14_HUMAN
NC score	0.169400 (rank : 676)	θ value	0.00509761 (rank : 563)
Query Neighborhood Hits	1113	Target Neighborhood Hits	409	Shared Neighborhood Hits	201
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

DGKI_HUMAN
NC score	0.169119 (rank : 677)	θ value	0.0563607 (rank : 663)
Query Neighborhood Hits	1113	Target Neighborhood Hits	609	Shared Neighborhood Hits	220
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

DGKZ_MOUSE
NC score	0.168602 (rank : 678)	θ value	0.813845 (rank : 816)
Query Neighborhood Hits	1113	Target Neighborhood Hits	542	Shared Neighborhood Hits	200
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

ST14_MOUSE
NC score	0.168560 (rank : 679)	θ value	0.000602161 (rank : 507)
Query Neighborhood Hits	1113	Target Neighborhood Hits	419	Shared Neighborhood Hits	212
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

C1RB_MOUSE
NC score	0.167986 (rank : 680)	θ value	0.00020696 (rank : 486)
Query Neighborhood Hits	1113	Target Neighborhood Hits	380	Shared Neighborhood Hits	177
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

CENG2_MOUSE
NC score	0.167925 (rank : 681)	θ value	0.47712 (rank : 776)
Query Neighborhood Hits	1113	Target Neighborhood Hits	463	Shared Neighborhood Hits	249
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

IKBL_MOUSE
NC score	0.167771 (rank : 682)	θ value	1.81305 (rank : 892)
Query Neighborhood Hits	1113	Target Neighborhood Hits	196	Shared Neighborhood Hits	140
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

ADA30_HUMAN
NC score	0.167404 (rank : 683)	θ value	5.81887e-07 (rank : 375)
Query Neighborhood Hits	1113	Target Neighborhood Hits	391	Shared Neighborhood Hits	164
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

CO9_MOUSE
NC score	0.167389 (rank : 684)	θ value	0.0736092 (rank : 671)
Query Neighborhood Hits	1113	Target Neighborhood Hits	153	Shared Neighborhood Hits	105
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

CENG2_HUMAN
NC score	0.167055 (rank : 685)	θ value	0.813845 (rank : 814)
Query Neighborhood Hits	1113	Target Neighborhood Hits	471	Shared Neighborhood Hits	250
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

ADAM7_HUMAN
NC score	0.165476 (rank : 686)	θ value	0.21417 (rank : 719)
Query Neighborhood Hits	1113	Target Neighborhood Hits	221	Shared Neighborhood Hits	179
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

VASN_HUMAN
NC score	0.163427 (rank : 687)	θ value	0.000270298 (rank : 496)
Query Neighborhood Hits	1113	Target Neighborhood Hits	449	Shared Neighborhood Hits	149
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

ADA21_MOUSE
NC score	0.161921 (rank : 688)	θ value	3.77169e-06 (rank : 415)
Query Neighborhood Hits	1113	Target Neighborhood Hits	172	Shared Neighborhood Hits	138
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

WFDC3_HUMAN
NC score	0.161410 (rank : 689)	θ value	θ > 10 (rank : 1323)
Query Neighborhood Hits	1113	Target Neighborhood Hits	138	Shared Neighborhood Hits	100
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

ADM1A_MOUSE
NC score	0.161157 (rank : 690)	θ value	0.00509761 (rank : 556)
Query Neighborhood Hits	1113	Target Neighborhood Hits	230	Shared Neighborhood Hits	193
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ADA10_HUMAN
NC score	0.160556 (rank : 691)	θ value	0.813845 (rank : 812)
Query Neighborhood Hits	1113	Target Neighborhood Hits	189	Shared Neighborhood Hits	149
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ADA17_HUMAN
NC score	0.160480 (rank : 692)	θ value	θ > 10 (rank : 1116)
Query Neighborhood Hits	1113	Target Neighborhood Hits	223	Shared Neighborhood Hits	166
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ADA22_HUMAN
NC score	0.160469 (rank : 693)	θ value	4.92598e-06 (rank : 419)
Query Neighborhood Hits	1113	Target Neighborhood Hits	211	Shared Neighborhood Hits	154
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ADA12_HUMAN
NC score	0.158899 (rank : 694)	θ value	0.00298849 (rank : 541)
Query Neighborhood Hits	1113	Target Neighborhood Hits	224	Shared Neighborhood Hits	161
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

MT3_HUMAN
NC score	0.157486 (rank : 695)	θ value	6.88961 (rank : 1066)
Query Neighborhood Hits	1113	Target Neighborhood Hits	82	Shared Neighborhood Hits	65
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

ADA18_HUMAN
NC score	0.154872 (rank : 696)	θ value	4.03905 (rank : 977)
Query Neighborhood Hits	1113	Target Neighborhood Hits	184	Shared Neighborhood Hits	153
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

ADA28_HUMAN
NC score	0.154372 (rank : 697)	θ value	0.163984 (rank : 708)
Query Neighborhood Hits	1113	Target Neighborhood Hits	244	Shared Neighborhood Hits	183
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

CLR59_HUMAN
NC score	0.154352 (rank : 698)	θ value	0.163984 (rank : 710)
Query Neighborhood Hits	1113	Target Neighborhood Hits	163	Shared Neighborhood Hits	139
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

CO8B_HUMAN
NC score	0.154220 (rank : 699)	θ value	0.0252991 (rank : 628)
Query Neighborhood Hits	1113	Target Neighborhood Hits	199	Shared Neighborhood Hits	106
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

ADA10_MOUSE
NC score	0.154067 (rank : 700)	θ value	5.27518 (rank : 1013)
Query Neighborhood Hits	1113	Target Neighborhood Hits	194	Shared Neighborhood Hits	151
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

GNPTA_HUMAN
NC score	0.153856 (rank : 701)	θ value	3.41135e-07 (rank : 369)
Query Neighborhood Hits	1113	Target Neighborhood Hits	43	Shared Neighborhood Hits	18
SwissProt Accessions	Q3T906, Q3ZQK2, Q6IPW5, Q86TQ2, Q96N13, Q9ULL2	Gene names	GNPTAB, GNPTA, KIAA1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

ADA28_MOUSE
NC score	0.153849 (rank : 702)	θ value	0.00869519 (rank : 580)
Query Neighborhood Hits	1113	Target Neighborhood Hits	241	Shared Neighborhood Hits	179
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ADA25_MOUSE
NC score	0.153102 (rank : 703)	θ value	0.0563607 (rank : 657)
Query Neighborhood Hits	1113	Target Neighborhood Hits	213	Shared Neighborhood Hits	167
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

ADAM2_HUMAN
NC score	0.152782 (rank : 704)	θ value	0.00228821 (rank : 535)
Query Neighborhood Hits	1113	Target Neighborhood Hits	175	Shared Neighborhood Hits	144
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

C1R_HUMAN
NC score	0.152745 (rank : 705)	θ value	0.00228821 (rank : 539)
Query Neighborhood Hits	1113	Target Neighborhood Hits	364	Shared Neighborhood Hits	168
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

TNR25_HUMAN
NC score	0.152678 (rank : 706)	θ value	1.81305 (rank : 905)
Query Neighborhood Hits	1113	Target Neighborhood Hits	172	Shared Neighborhood Hits	90
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

ADA21_HUMAN
NC score	0.152569 (rank : 707)	θ value	7.1131e-05 (rank : 462)
Query Neighborhood Hits	1113	Target Neighborhood Hits	181	Shared Neighborhood Hits	144
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

CO9_HUMAN
NC score	0.152532 (rank : 708)	θ value	0.47712 (rank : 778)
Query Neighborhood Hits	1113	Target Neighborhood Hits	147	Shared Neighborhood Hits	99
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

LCE2C_HUMAN
NC score	0.152524 (rank : 709)	θ value	θ > 10 (rank : 1225)
Query Neighborhood Hits	1113	Target Neighborhood Hits	53	Shared Neighborhood Hits	33
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

CD320_HUMAN
NC score	0.152301 (rank : 710)	θ value	θ > 10 (rank : 1135)
Query Neighborhood Hits	1113	Target Neighborhood Hits	103	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

GNPTA_MOUSE
NC score	0.151944 (rank : 711)	θ value	1.06045e-08 (rank : 309)
Query Neighborhood Hits	1113	Target Neighborhood Hits	47	Shared Neighborhood Hits	17
SwissProt Accessions	Q69ZN6, Q3U3K6, Q3US34	Gene names	Gnptab, Gnpta, Kiaa1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

ADA32_HUMAN
NC score	0.151554 (rank : 712)	θ value	0.125558 (rank : 694)
Query Neighborhood Hits	1113	Target Neighborhood Hits	216	Shared Neighborhood Hits	175
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

FST_MOUSE
NC score	0.151425 (rank : 713)	θ value	5.27518 (rank : 1026)
Query Neighborhood Hits	1113	Target Neighborhood Hits	146	Shared Neighborhood Hits	90
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

ADA24_MOUSE
NC score	0.150973 (rank : 714)	θ value	0.0431538 (rank : 646)
Query Neighborhood Hits	1113	Target Neighborhood Hits	230	Shared Neighborhood Hits	187
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ASTN_HUMAN
NC score	0.150889 (rank : 715)	θ value	θ > 10 (rank : 1124)
Query Neighborhood Hits	1113	Target Neighborhood Hits	105	Shared Neighborhood Hits	83
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

TRPV3_MOUSE
NC score	0.149467 (rank : 716)	θ value	0.00390308 (rank : 554)
Query Neighborhood Hits	1113	Target Neighborhood Hits	188	Shared Neighborhood Hits	130
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

VASN_MOUSE
NC score	0.149383 (rank : 717)	θ value	0.0148317 (rank : 614)
Query Neighborhood Hits	1113	Target Neighborhood Hits	426	Shared Neighborhood Hits	136
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

ASTN_MOUSE
NC score	0.149375 (rank : 718)	θ value	θ > 10 (rank : 1125)
Query Neighborhood Hits	1113	Target Neighborhood Hits	98	Shared Neighborhood Hits	79
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

ANKR9_MOUSE
NC score	0.148875 (rank : 719)	θ value	5.27518 (rank : 1016)
Query Neighborhood Hits	1113	Target Neighborhood Hits	120	Shared Neighborhood Hits	116
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ADA12_MOUSE
NC score	0.147192 (rank : 720)	θ value	0.00228821 (rank : 534)
Query Neighborhood Hits	1113	Target Neighborhood Hits	474	Shared Neighborhood Hits	236
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

KR124_HUMAN
NC score	0.146660 (rank : 721)	θ value	0.279714 (rank : 742)
Query Neighborhood Hits	1113	Target Neighborhood Hits	124	Shared Neighborhood Hits	97
SwissProt Accessions	P60329	Gene names	KRTAP12-4, KAP12.4, KRTAP12.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-4 (Keratin-associated protein 12.4) (High sulfur keratin-associated protein 12.4).

CS1A_MOUSE
NC score	0.146624 (rank : 722)	θ value	0.0148317 (rank : 606)
Query Neighborhood Hits	1113	Target Neighborhood Hits	360	Shared Neighborhood Hits	161
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

ESM1_MOUSE
NC score	0.145998 (rank : 723)	θ value	4.03905 (rank : 988)
Query Neighborhood Hits	1113	Target Neighborhood Hits	107	Shared Neighborhood Hits	74
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

CS1B_MOUSE
NC score	0.145462 (rank : 724)	θ value	0.0193708 (rank : 618)
Query Neighborhood Hits	1113	Target Neighborhood Hits	361	Shared Neighborhood Hits	159
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

MASP2_HUMAN
NC score	0.144859 (rank : 725)	θ value	0.125558 (rank : 700)
Query Neighborhood Hits	1113	Target Neighborhood Hits	364	Shared Neighborhood Hits	165
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

EPGN_MOUSE
NC score	0.144803 (rank : 726)	θ value	0.125558 (rank : 697)
Query Neighborhood Hits	1113	Target Neighborhood Hits	63	Shared Neighborhood Hits	59
SwissProt Accessions	Q924X1, Q8CEX5	Gene names	Epgn
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

ADA32_MOUSE
NC score	0.144205 (rank : 727)	θ value	4.03905 (rank : 978)
Query Neighborhood Hits	1113	Target Neighborhood Hits	219	Shared Neighborhood Hits	176
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADM1B_MOUSE
NC score	0.144114 (rank : 728)	θ value	0.47712 (rank : 771)
Query Neighborhood Hits	1113	Target Neighborhood Hits	236	Shared Neighborhood Hits	159
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

CO8A_HUMAN
NC score	0.143918 (rank : 729)	θ value	0.62314 (rank : 794)
Query Neighborhood Hits	1113	Target Neighborhood Hits	200	Shared Neighborhood Hits	115
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

MASP2_MOUSE
NC score	0.143727 (rank : 730)	θ value	0.0148317 (rank : 608)
Query Neighborhood Hits	1113	Target Neighborhood Hits	382	Shared Neighborhood Hits	172
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MEP1B_MOUSE
NC score	0.143529 (rank : 731)	θ value	0.21417 (rank : 727)
Query Neighborhood Hits	1113	Target Neighborhood Hits	127	Shared Neighborhood Hits	93
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

VEGFC_HUMAN
NC score	0.142466 (rank : 732)	θ value	θ > 10 (rank : 1322)
Query Neighborhood Hits	1113	Target Neighborhood Hits	128	Shared Neighborhood Hits	107
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

TRPV3_HUMAN
NC score	0.142342 (rank : 733)	θ value	0.00869519 (rank : 591)
Query Neighborhood Hits	1113	Target Neighborhood Hits	198	Shared Neighborhood Hits	141
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

C1S_HUMAN
NC score	0.141487 (rank : 734)	θ value	0.00869519 (rank : 583)
Query Neighborhood Hits	1113	Target Neighborhood Hits	359	Shared Neighborhood Hits	167
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

CO8A_MOUSE
NC score	0.140704 (rank : 735)	θ value	0.47712 (rank : 777)
Query Neighborhood Hits	1113	Target Neighborhood Hits	182	Shared Neighborhood Hits	96
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

LCE4A_HUMAN
NC score	0.139618 (rank : 736)	θ value	θ > 10 (rank : 1229)
Query Neighborhood Hits	1113	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

LRP10_HUMAN
NC score	0.139222 (rank : 737)	θ value	0.279714 (rank : 744)
Query Neighborhood Hits	1113	Target Neighborhood Hits	197	Shared Neighborhood Hits	113
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LCE2D_HUMAN
NC score	0.138877 (rank : 738)	θ value	θ > 10 (rank : 1226)
Query Neighborhood Hits	1113	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

ADAM7_MOUSE
NC score	0.138828 (rank : 739)	θ value	2.36792 (rank : 910)
Query Neighborhood Hits	1113	Target Neighborhood Hits	200	Shared Neighborhood Hits	160
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

MCSP_MOUSE
NC score	0.137931 (rank : 740)	θ value	5.27518 (rank : 1037)
Query Neighborhood Hits	1113	Target Neighborhood Hits	108	Shared Neighborhood Hits	65
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

FST_HUMAN
NC score	0.137822 (rank : 741)	θ value	2.36792 (rank : 919)
Query Neighborhood Hits	1113	Target Neighborhood Hits	129	Shared Neighborhood Hits	73
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

ADA29_HUMAN
NC score	0.137794 (rank : 742)	θ value	0.0193708 (rank : 616)
Query Neighborhood Hits	1113	Target Neighborhood Hits	247	Shared Neighborhood Hits	150
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

MKS3_MOUSE
NC score	0.137593 (rank : 743)	θ value	2.36792 (rank : 922)
Query Neighborhood Hits	1113	Target Neighborhood Hits	89	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

MKS3_HUMAN
NC score	0.137322 (rank : 744)	θ value	3.0926 (rank : 959)
Query Neighborhood Hits	1113	Target Neighborhood Hits	79	Shared Neighborhood Hits	68
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

LRP10_MOUSE
NC score	0.136589 (rank : 745)	θ value	θ > 10 (rank : 1235)
Query Neighborhood Hits	1113	Target Neighborhood Hits	169	Shared Neighborhood Hits	102
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

DDEF1_MOUSE
NC score	0.135642 (rank : 746)	θ value	θ > 10 (rank : 1168)
Query Neighborhood Hits	1113	Target Neighborhood Hits	592	Shared Neighborhood Hits	234
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

LRP12_HUMAN
NC score	0.135103 (rank : 747)	θ value	θ > 10 (rank : 1238)
Query Neighborhood Hits	1113	Target Neighborhood Hits	205	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

MASP1_HUMAN
NC score	0.134880 (rank : 748)	θ value	1.38821 (rank : 871)
Query Neighborhood Hits	1113	Target Neighborhood Hits	369	Shared Neighborhood Hits	166
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

TNR16_HUMAN
NC score	0.134130 (rank : 749)	θ value	θ > 10 (rank : 1301)
Query Neighborhood Hits	1113	Target Neighborhood Hits	183	Shared Neighborhood Hits	110
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

LRP12_MOUSE
NC score	0.133894 (rank : 750)	θ value	θ > 10 (rank : 1239)
Query Neighborhood Hits	1113	Target Neighborhood Hits	180	Shared Neighborhood Hits	107
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LCE2A_HUMAN
NC score	0.132604 (rank : 751)	θ value	θ > 10 (rank : 1223)
Query Neighborhood Hits	1113	Target Neighborhood Hits	50	Shared Neighborhood Hits	31
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

MASP1_MOUSE
NC score	0.132379 (rank : 752)	θ value	1.38821 (rank : 872)
Query Neighborhood Hits	1113	Target Neighborhood Hits	364	Shared Neighborhood Hits	167
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

MT4_HUMAN
NC score	0.132107 (rank : 753)	θ value	3.0926 (rank : 961)
Query Neighborhood Hits	1113	Target Neighborhood Hits	83	Shared Neighborhood Hits	61
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

ADA17_MOUSE
NC score	0.131372 (rank : 754)	θ value	θ > 10 (rank : 1117)
Query Neighborhood Hits	1113	Target Neighborhood Hits	201	Shared Neighborhood Hits	153
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

BTC_MOUSE
NC score	0.129835 (rank : 755)	θ value	0.279714 (rank : 737)
Query Neighborhood Hits	1113	Target Neighborhood Hits	67	Shared Neighborhood Hits	62
SwissProt Accessions	Q05928	Gene names	Btc, Bcn
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

EPGN_HUMAN
NC score	0.129294 (rank : 756)	θ value	0.163984 (rank : 715)
Query Neighborhood Hits	1113	Target Neighborhood Hits	59	Shared Neighborhood Hits	54
SwissProt Accessions	Q6UW88	Gene names	EPGN
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

LORI_MOUSE
NC score	0.127948 (rank : 757)	θ value	θ > 10 (rank : 1231)
Query Neighborhood Hits	1113	Target Neighborhood Hits	47	Shared Neighborhood Hits	21
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

TMPS6_HUMAN
NC score	0.127854 (rank : 758)	θ value	0.0431538 (rank : 656)
Query Neighborhood Hits	1113	Target Neighborhood Hits	338	Shared Neighborhood Hits	155
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

LCE2B_HUMAN
NC score	0.127356 (rank : 759)	θ value	θ > 10 (rank : 1224)
Query Neighborhood Hits	1113	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

TRPV1_MOUSE
NC score	0.126360 (rank : 760)	θ value	4.03905 (rank : 1011)
Query Neighborhood Hits	1113	Target Neighborhood Hits	189	Shared Neighborhood Hits	150
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

TRPV1_HUMAN
NC score	0.125673 (rank : 761)	θ value	0.813845 (rank : 830)
Query Neighborhood Hits	1113	Target Neighborhood Hits	184	Shared Neighborhood Hits	145
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

VEGFC_MOUSE
NC score	0.125222 (rank : 762)	θ value	2.36792 (rank : 939)
Query Neighborhood Hits	1113	Target Neighborhood Hits	119	Shared Neighborhood Hits	94
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

TNR16_MOUSE
NC score	0.124562 (rank : 763)	θ value	θ > 10 (rank : 1302)
Query Neighborhood Hits	1113	Target Neighborhood Hits	178	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

KR122_HUMAN
NC score	0.123468 (rank : 764)	θ value	θ > 10 (rank : 1210)
Query Neighborhood Hits	1113	Target Neighborhood Hits	97	Shared Neighborhood Hits	75
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

BAT4_MOUSE
NC score	0.123155 (rank : 765)	θ value	θ > 10 (rank : 1134)
Query Neighborhood Hits	1113	Target Neighborhood Hits	171	Shared Neighborhood Hits	120
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

ABTB1_MOUSE
NC score	0.122149 (rank : 766)	θ value	θ > 10 (rank : 1115)
Query Neighborhood Hits	1113	Target Neighborhood Hits	349	Shared Neighborhood Hits	171
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

AD26A_MOUSE
NC score	0.121442 (rank : 767)	θ value	0.00134147 (rank : 518)
Query Neighborhood Hits	1113	Target Neighborhood Hits	165	Shared Neighborhood Hits	129
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

TMPS6_MOUSE
NC score	0.121103 (rank : 768)	θ value	0.0193708 (rank : 624)
Query Neighborhood Hits	1113	Target Neighborhood Hits	341	Shared Neighborhood Hits	155
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

LCE3B_HUMAN
NC score	0.120735 (rank : 769)	θ value	θ > 10 (rank : 1228)
Query Neighborhood Hits	1113	Target Neighborhood Hits	47	Shared Neighborhood Hits	36
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

ANKR9_HUMAN
NC score	0.118830 (rank : 770)	θ value	θ > 10 (rank : 1121)
Query Neighborhood Hits	1113	Target Neighborhood Hits	99	Shared Neighborhood Hits	97
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

TRPV2_HUMAN
NC score	0.118781 (rank : 771)	θ value	1.38821 (rank : 882)
Query Neighborhood Hits	1113	Target Neighborhood Hits	130	Shared Neighborhood Hits	112
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

RSPO3_HUMAN
NC score	0.118757 (rank : 772)	θ value	0.0193708 (rank : 623)
Query Neighborhood Hits	1113	Target Neighborhood Hits	128	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

HBEGF_HUMAN
NC score	0.115217 (rank : 773)	θ value	0.365318 (rank : 760)
Query Neighborhood Hits	1113	Target Neighborhood Hits	61	Shared Neighborhood Hits	56
SwissProt Accessions	Q99075	Gene names	HBEGF, DTR, HEGFL
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF) (Diphtheria toxin receptor) (DT-R).

EREG_MOUSE
NC score	0.114036 (rank : 774)	θ value	3.0926 (rank : 949)
Query Neighborhood Hits	1113	Target Neighborhood Hits	65	Shared Neighborhood Hits	56
SwissProt Accessions	Q61521, Q7M0A8	Gene names	Ereg
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

BTC_HUMAN
NC score	0.113520 (rank : 775)	θ value	3.0926 (rank : 945)
Query Neighborhood Hits	1113	Target Neighborhood Hits	70	Shared Neighborhood Hits	63
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

ADA20_HUMAN
NC score	0.113337 (rank : 776)	θ value	0.00665767 (rank : 567)
Query Neighborhood Hits	1113	Target Neighborhood Hits	143	Shared Neighborhood Hits	102
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

PAPPA_HUMAN
NC score	0.110444 (rank : 777)	θ value	0.0736092 (rank : 677)
Query Neighborhood Hits	1113	Target Neighborhood Hits	161	Shared Neighborhood Hits	87
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PAPPA_MOUSE
NC score	0.108973 (rank : 778)	θ value	0.813845 (rank : 822)
Query Neighborhood Hits	1113	Target Neighborhood Hits	153	Shared Neighborhood Hits	84
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

ZNFX1_HUMAN
NC score	0.108387 (rank : 779)	θ value	2.36792 (rank : 941)
Query Neighborhood Hits	1113	Target Neighborhood Hits	308	Shared Neighborhood Hits	145
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

UROK_HUMAN
NC score	0.106013 (rank : 780)	θ value	0.125558 (rank : 704)
Query Neighborhood Hits	1113	Target Neighborhood Hits	272	Shared Neighborhood Hits	126
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

SPR2D_MOUSE
NC score	0.106012 (rank : 781)	θ value	0.0563607 (rank : 667)
Query Neighborhood Hits	1113	Target Neighborhood Hits	61	Shared Neighborhood Hits	32
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

ABTB1_HUMAN
NC score	0.105964 (rank : 782)	θ value	θ > 10 (rank : 1114)
Query Neighborhood Hits	1113	Target Neighborhood Hits	325	Shared Neighborhood Hits	156
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

TGFA_HUMAN
NC score	0.105686 (rank : 783)	θ value	3.0926 (rank : 971)
Query Neighborhood Hits	1113	Target Neighborhood Hits	61	Shared Neighborhood Hits	58
SwissProt Accessions	P01135, Q15577	Gene names	TGFA
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

SHBG_HUMAN
NC score	0.105158 (rank : 784)	θ value	θ > 10 (rank : 1276)
Query Neighborhood Hits	1113	Target Neighborhood Hits	45	Shared Neighborhood Hits	35
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

TNR9_HUMAN
NC score	0.104959 (rank : 785)	θ value	4.03905 (rank : 1009)
Query Neighborhood Hits	1113	Target Neighborhood Hits	166	Shared Neighborhood Hits	87
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

RSPO3_MOUSE
NC score	0.104761 (rank : 786)	θ value	0.00869519 (rank : 590)
Query Neighborhood Hits	1113	Target Neighborhood Hits	120	Shared Neighborhood Hits	70
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

UROK_MOUSE
NC score	0.104294 (rank : 787)	θ value	0.0563607 (rank : 668)
Query Neighborhood Hits	1113	Target Neighborhood Hits	273	Shared Neighborhood Hits	130
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

BAT4_HUMAN
NC score	0.103435 (rank : 788)	θ value	θ > 10 (rank : 1133)
Query Neighborhood Hits	1113	Target Neighborhood Hits	157	Shared Neighborhood Hits	108
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

ZNFX1_MOUSE
NC score	0.102747 (rank : 789)	θ value	θ > 10 (rank : 1328)
Query Neighborhood Hits	1113	Target Neighborhood Hits	407	Shared Neighborhood Hits	153
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

SHBG_MOUSE
NC score	0.102078 (rank : 790)	θ value	θ > 10 (rank : 1277)
Query Neighborhood Hits	1113	Target Neighborhood Hits	50	Shared Neighborhood Hits	40
SwissProt Accessions	P97497	Gene names	Shbg
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP).

NRG3_MOUSE
NC score	0.101504 (rank : 791)	θ value	1.81305 (rank : 902)
Query Neighborhood Hits	1113	Target Neighborhood Hits	132	Shared Neighborhood Hits	85
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

KR111_HUMAN
NC score	0.100789 (rank : 792)	θ value	5.27518 (rank : 1033)
Query Neighborhood Hits	1113	Target Neighborhood Hits	90	Shared Neighborhood Hits	73
SwissProt Accessions	Q8IUC1	Gene names	KRTAP11-1, KAP11.1, KRTAP11.1
Domain Architecture
Description	Keratin-associated protein 11-1 (High sulfur keratin-associated protein 11.1).

TNR14_HUMAN
NC score	0.099555 (rank : 793)	θ value	θ > 10 (rank : 1300)
Query Neighborhood Hits	1113	Target Neighborhood Hits	149	Shared Neighborhood Hits	81
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

RSNL2_HUMAN
NC score	0.099441 (rank : 794)	θ value	θ > 10 (rank : 1269)
Query Neighborhood Hits	1113	Target Neighborhood Hits	136	Shared Neighborhood Hits	110
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

GP128_MOUSE
NC score	0.099160 (rank : 795)	θ value	4.03905 (rank : 991)
Query Neighborhood Hits	1113	Target Neighborhood Hits	141	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BM96, Q80T42	Gene names	Gpr128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

MT1B_HUMAN
NC score	0.098956 (rank : 796)	θ value	0.62314 (rank : 801)
Query Neighborhood Hits	1113	Target Neighborhood Hits	87	Shared Neighborhood Hits	67
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

TNR8_MOUSE
NC score	0.098555 (rank : 797)	θ value	θ > 10 (rank : 1317)
Query Neighborhood Hits	1113	Target Neighborhood Hits	208	Shared Neighborhood Hits	99
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

NRG3_HUMAN
NC score	0.098122 (rank : 798)	θ value	1.81305 (rank : 901)
Query Neighborhood Hits	1113	Target Neighborhood Hits	119	Shared Neighborhood Hits	78
SwissProt Accessions	P56975	Gene names	NRG3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

TNR4_MOUSE
NC score	0.097550 (rank : 799)	θ value	θ > 10 (rank : 1310)
Query Neighborhood Hits	1113	Target Neighborhood Hits	137	Shared Neighborhood Hits	74
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

FINC_MOUSE
NC score	0.096026 (rank : 800)	θ value	3.0926 (rank : 951)
Query Neighborhood Hits	1113	Target Neighborhood Hits	309	Shared Neighborhood Hits	82
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

DKK3_MOUSE
NC score	0.095959 (rank : 801)	θ value	θ > 10 (rank : 1170)
Query Neighborhood Hits	1113	Target Neighborhood Hits	83	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

MEP1B_HUMAN
NC score	0.095009 (rank : 802)	θ value	0.0330416 (rank : 642)
Query Neighborhood Hits	1113	Target Neighborhood Hits	98	Shared Neighborhood Hits	65
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

FINC_HUMAN
NC score	0.094831 (rank : 803)	θ value	5.27518 (rank : 1024)
Query Neighborhood Hits	1113	Target Neighborhood Hits	302	Shared Neighborhood Hits	72
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

SPR2G_MOUSE
NC score	0.093977 (rank : 804)	θ value	θ > 10 (rank : 1281)
Query Neighborhood Hits	1113	Target Neighborhood Hits	53	Shared Neighborhood Hits	26
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

GP128_HUMAN
NC score	0.093660 (rank : 805)	θ value	4.03905 (rank : 990)
Query Neighborhood Hits	1113	Target Neighborhood Hits	135	Shared Neighborhood Hits	53
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

BAI1_HUMAN
NC score	0.093558 (rank : 806)	θ value	0.21417 (rank : 722)
Query Neighborhood Hits	1113	Target Neighborhood Hits	375	Shared Neighborhood Hits	102
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

CYR61_MOUSE
NC score	0.092730 (rank : 807)	θ value	1.38821 (rank : 866)
Query Neighborhood Hits	1113	Target Neighborhood Hits	156	Shared Neighborhood Hits	80
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

LCE5A_HUMAN
NC score	0.092407 (rank : 808)	θ value	θ > 10 (rank : 1230)
Query Neighborhood Hits	1113	Target Neighborhood Hits	43	Shared Neighborhood Hits	22
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

CT127_HUMAN
NC score	0.091782 (rank : 809)	θ value	θ > 10 (rank : 1162)
Query Neighborhood Hits	1113	Target Neighborhood Hits	67	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

TNR7_HUMAN
NC score	0.091594 (rank : 810)	θ value	θ > 10 (rank : 1314)
Query Neighborhood Hits	1113	Target Neighborhood Hits	120	Shared Neighborhood Hits	72
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

CMTA2_HUMAN
NC score	0.090619 (rank : 811)	θ value	0.163984 (rank : 711)
Query Neighborhood Hits	1113	Target Neighborhood Hits	199	Shared Neighborhood Hits	107
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

TNR4_HUMAN
NC score	0.090373 (rank : 812)	θ value	θ > 10 (rank : 1309)
Query Neighborhood Hits	1113	Target Neighborhood Hits	152	Shared Neighborhood Hits	85
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

KR123_HUMAN
NC score	0.089855 (rank : 813)	θ value	θ > 10 (rank : 1211)
Query Neighborhood Hits	1113	Target Neighborhood Hits	75	Shared Neighborhood Hits	55
SwissProt Accessions	P60328	Gene names	KRTAP12-3, KAP12.3, KRTAP12.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-3 (Keratin-associated protein 12.3) (High sulfur keratin-associated protein 12.3).

CYR61_HUMAN
NC score	0.089786 (rank : 814)	θ value	1.38821 (rank : 865)
Query Neighborhood Hits	1113	Target Neighborhood Hits	159	Shared Neighborhood Hits	84
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

TGFA_MOUSE
NC score	0.089339 (rank : 815)	θ value	2.36792 (rank : 935)
Query Neighborhood Hits	1113	Target Neighborhood Hits	62	Shared Neighborhood Hits	56
SwissProt Accessions	P48030	Gene names	Tgfa
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

CMTA1_HUMAN
NC score	0.089286 (rank : 816)	θ value	θ > 10 (rank : 1141)
Query Neighborhood Hits	1113	Target Neighborhood Hits	217	Shared Neighborhood Hits	115
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

RSNL2_MOUSE
NC score	0.088955 (rank : 817)	θ value	θ > 10 (rank : 1270)
Query Neighborhood Hits	1113	Target Neighborhood Hits	129	Shared Neighborhood Hits	97
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

MT1A_HUMAN
NC score	0.088880 (rank : 818)	θ value	θ > 10 (rank : 1243)
Query Neighborhood Hits	1113	Target Neighborhood Hits	74	Shared Neighborhood Hits	56
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

BAI3_MOUSE
NC score	0.088682 (rank : 819)	θ value	θ > 10 (rank : 1132)
Query Neighborhood Hits	1113	Target Neighborhood Hits	250	Shared Neighborhood Hits	79
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

RSPO4_HUMAN
NC score	0.087548 (rank : 820)	θ value	θ > 10 (rank : 1273)
Query Neighborhood Hits	1113	Target Neighborhood Hits	110	Shared Neighborhood Hits	73
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

CFAI_MOUSE
NC score	0.086952 (rank : 821)	θ value	6.88961 (rank : 1060)
Query Neighborhood Hits	1113	Target Neighborhood Hits	290	Shared Neighborhood Hits	100
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

BAI1_MOUSE
NC score	0.086744 (rank : 822)	θ value	1.81305 (rank : 886)
Query Neighborhood Hits	1113	Target Neighborhood Hits	340	Shared Neighborhood Hits	96
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI3_HUMAN
NC score	0.086210 (rank : 823)	θ value	θ > 10 (rank : 1131)
Query Neighborhood Hits	1113	Target Neighborhood Hits	246	Shared Neighborhood Hits	76
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

CTGF_HUMAN
NC score	0.085776 (rank : 824)	θ value	0.0193708 (rank : 619)
Query Neighborhood Hits	1113	Target Neighborhood Hits	128	Shared Neighborhood Hits	62
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

HBEGF_MOUSE
NC score	0.085697 (rank : 825)	θ value	1.81305 (rank : 890)
Query Neighborhood Hits	1113	Target Neighborhood Hits	48	Shared Neighborhood Hits	46
SwissProt Accessions	Q06186	Gene names	Hbegf, Dtr, Hegfl
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF).

BAI2_MOUSE
NC score	0.085001 (rank : 826)	θ value	θ > 10 (rank : 1130)
Query Neighborhood Hits	1113	Target Neighborhood Hits	323	Shared Neighborhood Hits	94
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

MT2_MOUSE
NC score	0.084943 (rank : 827)	θ value	θ > 10 (rank : 1249)
Query Neighborhood Hits	1113	Target Neighborhood Hits	81	Shared Neighborhood Hits	53
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

TRPV2_MOUSE
NC score	0.084641 (rank : 828)	θ value	θ > 10 (rank : 1319)
Query Neighborhood Hits	1113	Target Neighborhood Hits	111	Shared Neighborhood Hits	92
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

DKK3_HUMAN
NC score	0.084568 (rank : 829)	θ value	θ > 10 (rank : 1169)
Query Neighborhood Hits	1113	Target Neighborhood Hits	74	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UBP4, Q9ULB7	Gene names	DKK3, REIC
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3).

TSG6_HUMAN
NC score	0.083845 (rank : 830)	θ value	θ > 10 (rank : 1320)
Query Neighborhood Hits	1113	Target Neighborhood Hits	91	Shared Neighborhood Hits	39
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

BAI2_HUMAN
NC score	0.083789 (rank : 831)	θ value	θ > 10 (rank : 1129)
Query Neighborhood Hits	1113	Target Neighborhood Hits	332	Shared Neighborhood Hits	98
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

TSG6_MOUSE
NC score	0.083756 (rank : 832)	θ value	θ > 10 (rank : 1321)
Query Neighborhood Hits	1113	Target Neighborhood Hits	91	Shared Neighborhood Hits	38
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

MT1X_HUMAN
NC score	0.082852 (rank : 833)	θ value	θ > 10 (rank : 1247)
Query Neighborhood Hits	1113	Target Neighborhood Hits	76	Shared Neighborhood Hits	55
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

TNR11_HUMAN
NC score	0.082814 (rank : 834)	θ value	θ > 10 (rank : 1298)
Query Neighborhood Hits	1113	Target Neighborhood Hits	135	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

SPR2H_MOUSE
NC score	0.082737 (rank : 835)	θ value	6.88961 (rank : 1073)
Query Neighborhood Hits	1113	Target Neighborhood Hits	82	Shared Neighborhood Hits	39
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

CTGF_MOUSE
NC score	0.082409 (rank : 836)	θ value	0.365318 (rank : 753)
Query Neighborhood Hits	1113	Target Neighborhood Hits	124	Shared Neighborhood Hits	66
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

CFAI_HUMAN
NC score	0.082337 (rank : 837)	θ value	θ > 10 (rank : 1138)
Query Neighborhood Hits	1113	Target Neighborhood Hits	289	Shared Neighborhood Hits	94
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

TMPS7_HUMAN
NC score	0.082167 (rank : 838)	θ value	θ > 10 (rank : 1294)
Query Neighborhood Hits	1113	Target Neighborhood Hits	275	Shared Neighborhood Hits	103
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TNR8_HUMAN
NC score	0.081629 (rank : 839)	θ value	θ > 10 (rank : 1316)
Query Neighborhood Hits	1113	Target Neighborhood Hits	198	Shared Neighborhood Hits	99
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TMPS7_MOUSE
NC score	0.081546 (rank : 840)	θ value	θ > 10 (rank : 1295)
Query Neighborhood Hits	1113	Target Neighborhood Hits	275	Shared Neighborhood Hits	100
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

CMTA2_MOUSE
NC score	0.081481 (rank : 841)	θ value	0.279714 (rank : 739)
Query Neighborhood Hits	1113	Target Neighborhood Hits	216	Shared Neighborhood Hits	98
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CHRD_HUMAN
NC score	0.081457 (rank : 842)	θ value	θ > 10 (rank : 1139)
Query Neighborhood Hits	1113	Target Neighborhood Hits	102	Shared Neighborhood Hits	66
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

TRPV4_HUMAN
NC score	0.081452 (rank : 843)	θ value	0.62314 (rank : 810)
Query Neighborhood Hits	1113	Target Neighborhood Hits	150	Shared Neighborhood Hits	87
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

KR241_HUMAN
NC score	0.081257 (rank : 844)	θ value	θ > 10 (rank : 1217)
Query Neighborhood Hits	1113	Target Neighborhood Hits	71	Shared Neighborhood Hits	53
SwissProt Accessions	Q3LI83	Gene names	KRTAP24-1, KAP24.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 24-1.

PAP2_HUMAN
NC score	0.081247 (rank : 845)	θ value	0.0961366 (rank : 688)
Query Neighborhood Hits	1113	Target Neighborhood Hits	106	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

GP126_HUMAN
NC score	0.081086 (rank : 846)	θ value	θ > 10 (rank : 1189)
Query Neighborhood Hits	1113	Target Neighborhood Hits	187	Shared Neighborhood Hits	48
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

GP113_HUMAN
NC score	0.080557 (rank : 847)	θ value	θ > 10 (rank : 1180)
Query Neighborhood Hits	1113	Target Neighborhood Hits	102	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IZF5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3	Gene names	GPR113, PGR23
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 113 precursor (G-protein coupled receptor PGR23).

MFRP_HUMAN
NC score	0.080548 (rank : 848)	θ value	1.81305 (rank : 895)
Query Neighborhood Hits	1113	Target Neighborhood Hits	165	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

SPR2B_MOUSE
NC score	0.080179 (rank : 849)	θ value	2.36792 (rank : 932)
Query Neighborhood Hits	1113	Target Neighborhood Hits	51	Shared Neighborhood Hits	28
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

KR261_HUMAN
NC score	0.078292 (rank : 850)	θ value	θ > 10 (rank : 1218)
Query Neighborhood Hits	1113	Target Neighborhood Hits	65	Shared Neighborhood Hits	49
SwissProt Accessions	Q6PEX3	Gene names	KRTAP26-1, KAP26.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 26-1.

NEU1_MOUSE
NC score	0.078065 (rank : 851)	θ value	4.03905 (rank : 998)
Query Neighborhood Hits	1113	Target Neighborhood Hits	64	Shared Neighborhood Hits	51
SwissProt Accessions	P35454	Gene names	Oxt
Domain Architecture
Description	Oxytocin-neurophysin 1 precursor (OT-NPI) [Contains: Oxytocin (Ocytocin); Neurophysin 1].

TNR5_MOUSE
NC score	0.077948 (rank : 852)	θ value	0.62314 (rank : 807)
Query Neighborhood Hits	1113	Target Neighborhood Hits	131	Shared Neighborhood Hits	71
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

RSPO4_MOUSE
NC score	0.077797 (rank : 853)	θ value	θ > 10 (rank : 1274)
Query Neighborhood Hits	1113	Target Neighborhood Hits	110	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

TNR9_MOUSE
NC score	0.077028 (rank : 854)	θ value	θ > 10 (rank : 1318)
Query Neighborhood Hits	1113	Target Neighborhood Hits	137	Shared Neighborhood Hits	81
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

LCE3C_HUMAN
NC score	0.076492 (rank : 855)	θ value	1.38821 (rank : 870)
Query Neighborhood Hits	1113	Target Neighborhood Hits	15	Shared Neighborhood Hits	11
SwissProt Accessions	Q5T5A8	Gene names	LCE3C, LEP15, SPRL3A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A).

IDD_HUMAN
NC score	0.076252 (rank : 856)	θ value	θ > 10 (rank : 1208)
Query Neighborhood Hits	1113	Target Neighborhood Hits	127	Shared Neighborhood Hits	55
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

SPR2F_HUMAN
NC score	0.076248 (rank : 857)	θ value	θ > 10 (rank : 1280)
Query Neighborhood Hits	1113	Target Neighborhood Hits	33	Shared Neighborhood Hits	17
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

CRDL2_MOUSE
NC score	0.076096 (rank : 858)	θ value	θ > 10 (rank : 1155)
Query Neighborhood Hits	1113	Target Neighborhood Hits	81	Shared Neighborhood Hits	56
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

CHRD_MOUSE
NC score	0.075875 (rank : 859)	θ value	θ > 10 (rank : 1140)
Query Neighborhood Hits	1113	Target Neighborhood Hits	102	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

GP144_HUMAN
NC score	0.075854 (rank : 860)	θ value	θ > 10 (rank : 1191)
Query Neighborhood Hits	1113	Target Neighborhood Hits	108	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

MT1_MOUSE
NC score	0.075335 (rank : 861)	θ value	θ > 10 (rank : 1248)
Query Neighborhood Hits	1113	Target Neighborhood Hits	72	Shared Neighborhood Hits	48
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

GP112_HUMAN
NC score	0.075027 (rank : 862)	θ value	θ > 10 (rank : 1179)
Query Neighborhood Hits	1113	Target Neighborhood Hits	441	Shared Neighborhood Hits	87
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

MT1H_HUMAN
NC score	0.074343 (rank : 863)	θ value	θ > 10 (rank : 1246)
Query Neighborhood Hits	1113	Target Neighborhood Hits	78	Shared Neighborhood Hits	56
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

TMG1_HUMAN
NC score	0.074315 (rank : 864)	θ value	θ > 10 (rank : 1284)
Query Neighborhood Hits	1113	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	O14668	Gene names	PRRG1, PRGP1, TMG1
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 1 precursor (Proline- rich Gla protein 1) (Proline-rich gamma-carboxyglutamic acid protein 1).

CRDL2_HUMAN
NC score	0.073876 (rank : 865)	θ value	θ > 10 (rank : 1154)
Query Neighborhood Hits	1113	Target Neighborhood Hits	99	Shared Neighborhood Hits	59
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

GP133_HUMAN
NC score	0.073605 (rank : 866)	θ value	θ > 10 (rank : 1190)
Query Neighborhood Hits	1113	Target Neighborhood Hits	115	Shared Neighborhood Hits	20
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

WISP2_HUMAN
NC score	0.072715 (rank : 867)	θ value	θ > 10 (rank : 1326)
Query Neighborhood Hits	1113	Target Neighborhood Hits	126	Shared Neighborhood Hits	58
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

TNR23_MOUSE
NC score	0.072378 (rank : 868)	θ value	θ > 10 (rank : 1306)
Query Neighborhood Hits	1113	Target Neighborhood Hits	114	Shared Neighborhood Hits	67
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

LPHN2_HUMAN
NC score	0.072126 (rank : 869)	θ value	θ > 10 (rank : 1233)
Query Neighborhood Hits	1113	Target Neighborhood Hits	136	Shared Neighborhood Hits	24
SwissProt Accessions	O95490, O94882, Q5VX76, Q9UKY5, Q9UKY6	Gene names	LPHN2, KIAA0786, LEC1, LPHH1
Domain Architecture
Description	Latrophilin-2 precursor (Calcium-independent alpha-latrotoxin receptor 2) (Latrophilin homolog 1) (Lectomedin-1).

LPHN3_HUMAN
NC score	0.071490 (rank : 870)	θ value	θ > 10 (rank : 1234)
Query Neighborhood Hits	1113	Target Neighborhood Hits	139	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

LPHN1_HUMAN
NC score	0.071393 (rank : 871)	θ value	θ > 10 (rank : 1232)
Query Neighborhood Hits	1113	Target Neighborhood Hits	155	Shared Neighborhood Hits	27
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

IDD_MOUSE
NC score	0.071388 (rank : 872)	θ value	θ > 10 (rank : 1209)
Query Neighborhood Hits	1113	Target Neighborhood Hits	151	Shared Neighborhood Hits	56
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

CSMD1_MOUSE
NC score	0.071284 (rank : 873)	θ value	θ > 10 (rank : 1156)
Query Neighborhood Hits	1113	Target Neighborhood Hits	193	Shared Neighborhood Hits	84
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

PROP_MOUSE
NC score	0.071260 (rank : 874)	θ value	θ > 10 (rank : 1268)
Query Neighborhood Hits	1113	Target Neighborhood Hits	165	Shared Neighborhood Hits	72
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

CSMD1_HUMAN
NC score	0.071131 (rank : 875)	θ value	3.0926 (rank : 946)
Query Neighborhood Hits	1113	Target Neighborhood Hits	176	Shared Neighborhood Hits	75
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

COCA1_MOUSE
NC score	0.071098 (rank : 876)	θ value	θ > 10 (rank : 1146)
Query Neighborhood Hits	1113	Target Neighborhood Hits	467	Shared Neighborhood Hits	80
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

ENTK_MOUSE
NC score	0.070947 (rank : 877)	θ value	θ > 10 (rank : 1172)
Query Neighborhood Hits	1113	Target Neighborhood Hits	338	Shared Neighborhood Hits	104
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

GP116_HUMAN
NC score	0.070656 (rank : 878)	θ value	5.27518 (rank : 1028)
Query Neighborhood Hits	1113	Target Neighborhood Hits	167	Shared Neighborhood Hits	38
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

ADEC1_MOUSE
NC score	0.070470 (rank : 879)	θ value	θ > 10 (rank : 1119)
Query Neighborhood Hits	1113	Target Neighborhood Hits	85	Shared Neighborhood Hits	53
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

NCOA6_MOUSE
NC score	0.070420 (rank : 880)	θ value	1.09739e-05 (rank : 438)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1076	Shared Neighborhood Hits	231
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

CSMD3_HUMAN
NC score	0.069832 (rank : 881)	θ value	θ > 10 (rank : 1158)
Query Neighborhood Hits	1113	Target Neighborhood Hits	199	Shared Neighborhood Hits	76
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

RSPO2_MOUSE
NC score	0.069773 (rank : 882)	θ value	8.99809 (rank : 1104)
Query Neighborhood Hits	1113	Target Neighborhood Hits	88	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

GPR64_MOUSE
NC score	0.069527 (rank : 883)	θ value	θ > 10 (rank : 1195)
Query Neighborhood Hits	1113	Target Neighborhood Hits	156	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

MFRP_MOUSE
NC score	0.069017 (rank : 884)	θ value	θ > 10 (rank : 1242)
Query Neighborhood Hits	1113	Target Neighborhood Hits	166	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

TRPV4_MOUSE
NC score	0.068785 (rank : 885)	θ value	0.47712 (rank : 791)
Query Neighborhood Hits	1113	Target Neighborhood Hits	117	Shared Neighborhood Hits	76
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TNR26_MOUSE
NC score	0.068783 (rank : 886)	θ value	θ > 10 (rank : 1307)
Query Neighborhood Hits	1113	Target Neighborhood Hits	106	Shared Neighborhood Hits	64
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

GP125_HUMAN
NC score	0.068726 (rank : 887)	θ value	θ > 10 (rank : 1187)
Query Neighborhood Hits	1113	Target Neighborhood Hits	327	Shared Neighborhood Hits	38
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

GPR64_HUMAN
NC score	0.068515 (rank : 888)	θ value	θ > 10 (rank : 1194)
Query Neighborhood Hits	1113	Target Neighborhood Hits	207	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

GP114_HUMAN
NC score	0.068359 (rank : 889)	θ value	θ > 10 (rank : 1181)
Query Neighborhood Hits	1113	Target Neighborhood Hits	75	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IZF4, Q6ZMH7, Q6ZML4, Q86SL8, Q8IZ14	Gene names	GPR114, PGR27
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 114 precursor (G-protein coupled receptor PGR27).

NCOA6_HUMAN
NC score	0.068273 (rank : 890)	θ value	0.47712 (rank : 784)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1202	Shared Neighborhood Hits	238
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

GP124_MOUSE
NC score	0.068106 (rank : 891)	θ value	θ > 10 (rank : 1186)
Query Neighborhood Hits	1113	Target Neighborhood Hits	423	Shared Neighborhood Hits	52
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

COKA1_HUMAN
NC score	0.067662 (rank : 892)	θ value	θ > 10 (rank : 1149)
Query Neighborhood Hits	1113	Target Neighborhood Hits	403	Shared Neighborhood Hits	80
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

RSPO2_HUMAN
NC score	0.067564 (rank : 893)	θ value	θ > 10 (rank : 1272)
Query Neighborhood Hits	1113	Target Neighborhood Hits	90	Shared Neighborhood Hits	53
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

NOV_HUMAN
NC score	0.067515 (rank : 894)	θ value	θ > 10 (rank : 1256)
Query Neighborhood Hits	1113	Target Neighborhood Hits	128	Shared Neighborhood Hits	70
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

KR131_HUMAN
NC score	0.067471 (rank : 895)	θ value	θ > 10 (rank : 1212)
Query Neighborhood Hits	1113	Target Neighborhood Hits	123	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IUC0, Q3LI79	Gene names	KRTAP13-1, KAP13.1, KRTAP13.1
Domain Architecture
Description	Keratin-associated protein 13-1 (High sulfur keratin-associated protein 13.1).

ANKF1_HUMAN
NC score	0.067376 (rank : 896)	θ value	θ > 10 (rank : 1120)
Query Neighborhood Hits	1113	Target Neighborhood Hits	126	Shared Neighborhood Hits	79
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

COCA1_HUMAN
NC score	0.067214 (rank : 897)	θ value	θ > 10 (rank : 1145)
Query Neighborhood Hits	1113	Target Neighborhood Hits	458	Shared Neighborhood Hits	72
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

ADEC1_HUMAN
NC score	0.067211 (rank : 898)	θ value	θ > 10 (rank : 1118)
Query Neighborhood Hits	1113	Target Neighborhood Hits	80	Shared Neighborhood Hits	46
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

TMG3_HUMAN
NC score	0.067058 (rank : 899)	θ value	θ > 10 (rank : 1287)
Query Neighborhood Hits	1113	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BZD7, Q8N2N6	Gene names	PRRG3, TMG3
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 3 precursor (Proline- rich Gla protein 3) (Proline-rich gamma-carboxyglutamic acid protein 3).

ENTK_HUMAN
NC score	0.066974 (rank : 900)	θ value	θ > 10 (rank : 1171)
Query Neighborhood Hits	1113	Target Neighborhood Hits	310	Shared Neighborhood Hits	97
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

NRP2_HUMAN
NC score	0.066864 (rank : 901)	θ value	θ > 10 (rank : 1259)
Query Neighborhood Hits	1113	Target Neighborhood Hits	120	Shared Neighborhood Hits	46
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

TMG3_MOUSE
NC score	0.066478 (rank : 902)	θ value	θ > 10 (rank : 1288)
Query Neighborhood Hits	1113	Target Neighborhood Hits	30	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PAQ9	Gene names	Prrg3, Gm368, Tmg3
Domain Architecture	No domain graphic available
Description	Transmembrane gamma-carboxyglutamic acid protein 3 precursor (Proline- rich Gla protein 3) (Proline-rich gamma-carboxyglutamic acid protein 3).

GP179_HUMAN
NC score	0.066221 (rank : 903)	θ value	0.813845 (rank : 818)
Query Neighborhood Hits	1113	Target Neighborhood Hits	372	Shared Neighborhood Hits	78
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

HPLN2_MOUSE
NC score	0.066168 (rank : 904)	θ value	θ > 10 (rank : 1203)
Query Neighborhood Hits	1113	Target Neighborhood Hits	102	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ESM3	Gene names	Hapln2, Bral1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

ODFP_MOUSE
NC score	0.065745 (rank : 905)	θ value	θ > 10 (rank : 1264)
Query Neighborhood Hits	1113	Target Neighborhood Hits	75	Shared Neighborhood Hits	44
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

HPLN3_MOUSE
NC score	0.065367 (rank : 906)	θ value	θ > 10 (rank : 1205)
Query Neighborhood Hits	1113	Target Neighborhood Hits	95	Shared Neighborhood Hits	13
SwissProt Accessions	Q80WM5, Q80XX3	Gene names	Hapln3, Lpr3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor (Link protein 3).

HPLN2_HUMAN
NC score	0.065298 (rank : 907)	θ value	θ > 10 (rank : 1202)
Query Neighborhood Hits	1113	Target Neighborhood Hits	80	Shared Neighborhood Hits	15
SwissProt Accessions	Q9GZV7	Gene names	HAPLN2, BRAL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

MLL3_HUMAN
NC score	0.065100 (rank : 908)	θ value	5.27518 (rank : 1039)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1644	Shared Neighborhood Hits	313
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

GP124_HUMAN
NC score	0.065060 (rank : 909)	θ value	θ > 10 (rank : 1185)
Query Neighborhood Hits	1113	Target Neighborhood Hits	304	Shared Neighborhood Hits	40
SwissProt Accessions	Q96PE1, Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4	Gene names	GPR124, KIAA1531, TEM5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

MT1L_HUMAN
NC score	0.064744 (rank : 910)	θ value	2.36792 (rank : 924)
Query Neighborhood Hits	1113	Target Neighborhood Hits	73	Shared Neighborhood Hits	52
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

GP125_MOUSE
NC score	0.064652 (rank : 911)	θ value	θ > 10 (rank : 1188)
Query Neighborhood Hits	1113	Target Neighborhood Hits	329	Shared Neighborhood Hits	40
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

GPR97_MOUSE
NC score	0.064427 (rank : 912)	θ value	θ > 10 (rank : 1197)
Query Neighborhood Hits	1113	Target Neighborhood Hits	89	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R0T6	Gene names	Gpr97
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor.

NRP2_MOUSE
NC score	0.064176 (rank : 913)	θ value	θ > 10 (rank : 1260)
Query Neighborhood Hits	1113	Target Neighborhood Hits	113	Shared Neighborhood Hits	43
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

TNR11_MOUSE
NC score	0.064176 (rank : 914)	θ value	θ > 10 (rank : 1299)
Query Neighborhood Hits	1113	Target Neighborhood Hits	121	Shared Neighborhood Hits	63
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

COEA1_MOUSE
NC score	0.064113 (rank : 915)	θ value	θ > 10 (rank : 1148)
Query Neighborhood Hits	1113	Target Neighborhood Hits	402	Shared Neighborhood Hits	63
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

GPR56_HUMAN
NC score	0.063973 (rank : 916)	θ value	θ > 10 (rank : 1192)
Query Neighborhood Hits	1113	Target Neighborhood Hits	84	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y653, O95966, Q8NGB3, Q96HB4	Gene names	GPR56, TM7LN4, TM7XN1
Domain Architecture
Description	G-protein coupled receptor 56 precursor (TM7XN1 protein).

GPR56_MOUSE
NC score	0.063897 (rank : 917)	θ value	θ > 10 (rank : 1193)
Query Neighborhood Hits	1113	Target Neighborhood Hits	89	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K209, Q3UR17, Q9QZT2	Gene names	Gpr56, Cyt28
Domain Architecture
Description	G-protein coupled receptor 56 precursor (Serpentine receptor cyt28).

HPLN3_HUMAN
NC score	0.063878 (rank : 918)	θ value	θ > 10 (rank : 1204)
Query Neighborhood Hits	1113	Target Neighborhood Hits	70	Shared Neighborhood Hits	12
SwissProt Accessions	Q96S86	Gene names	HAPLN3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor.

KR134_HUMAN
NC score	0.063667 (rank : 919)	θ value	θ > 10 (rank : 1215)
Query Neighborhood Hits	1113	Target Neighborhood Hits	81	Shared Neighborhood Hits	56
SwissProt Accessions	Q3LI77	Gene names	KRTAP13-4, KAP13.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-4.

NACAM_MOUSE
NC score	0.063328 (rank : 920)	θ value	0.62314 (rank : 803)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1866	Shared Neighborhood Hits	295
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

SPR2I_MOUSE
NC score	0.063294 (rank : 921)	θ value	0.365318 (rank : 767)
Query Neighborhood Hits	1113	Target Neighborhood Hits	45	Shared Neighborhood Hits	20
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

HPLN4_MOUSE
NC score	0.063079 (rank : 922)	θ value	θ > 10 (rank : 1207)
Query Neighborhood Hits	1113	Target Neighborhood Hits	98	Shared Neighborhood Hits	16
SwissProt Accessions	Q80WM4, Q80XX2	Gene names	Hapln4, Bral2, Lpr4
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2) (Link protein 4).

CSMD2_HUMAN
NC score	0.063077 (rank : 923)	θ value	θ > 10 (rank : 1157)
Query Neighborhood Hits	1113	Target Neighborhood Hits	188	Shared Neighborhood Hits	72
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

NRP1_MOUSE
NC score	0.062906 (rank : 924)	θ value	θ > 10 (rank : 1258)
Query Neighborhood Hits	1113	Target Neighborhood Hits	120	Shared Neighborhood Hits	46
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

MLL3_MOUSE
NC score	0.062902 (rank : 925)	θ value	1.81305 (rank : 897)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1399	Shared Neighborhood Hits	282
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

HPLN1_MOUSE
NC score	0.062891 (rank : 926)	θ value	θ > 10 (rank : 1201)
Query Neighborhood Hits	1113	Target Neighborhood Hits	64	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QUP5, Q9D1G9, Q9Z1X7	Gene names	Hapln1, Crtl1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

NRP1_HUMAN
NC score	0.062880 (rank : 927)	θ value	θ > 10 (rank : 1257)
Query Neighborhood Hits	1113	Target Neighborhood Hits	119	Shared Neighborhood Hits	47
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

HPLN1_HUMAN
NC score	0.062871 (rank : 928)	θ value	θ > 10 (rank : 1200)
Query Neighborhood Hits	1113	Target Neighborhood Hits	67	Shared Neighborhood Hits	13
SwissProt Accessions	P10915	Gene names	HAPLN1, CRTL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

CFAB_MOUSE
NC score	0.062544 (rank : 929)	θ value	θ > 10 (rank : 1137)
Query Neighborhood Hits	1113	Target Neighborhood Hits	262	Shared Neighborhood Hits	72
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

HPLN4_HUMAN
NC score	0.062519 (rank : 930)	θ value	θ > 10 (rank : 1206)
Query Neighborhood Hits	1113	Target Neighborhood Hits	100	Shared Neighborhood Hits	15
SwissProt Accessions	Q86UW8, Q96PW2	Gene names	HAPLN4, BRAL2, KIAA1926
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2).

GP110_MOUSE
NC score	0.062185 (rank : 931)	θ value	θ > 10 (rank : 1177)
Query Neighborhood Hits	1113	Target Neighborhood Hits	92	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VEC3, Q8BMV8	Gene names	Gpr110
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 110 precursor.

GP110_HUMAN
NC score	0.062148 (rank : 932)	θ value	θ > 10 (rank : 1176)
Query Neighborhood Hits	1113	Target Neighborhood Hits	87	Shared Neighborhood Hits	28
SwissProt Accessions	Q5T601, Q5KU15, Q5T5Z9, Q86SM1, Q8IXE3, Q8IZF8, Q96DQ1	Gene names	GPR110, PGR19
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 110 precursor (G-protein coupled receptor PGR19) (G-protein coupled receptor KPG_012).

NETO1_HUMAN
NC score	0.062133 (rank : 933)	θ value	θ > 10 (rank : 1252)
Query Neighborhood Hits	1113	Target Neighborhood Hits	110	Shared Neighborhood Hits	61
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

TNR7_MOUSE
NC score	0.062000 (rank : 934)	θ value	θ > 10 (rank : 1315)
Query Neighborhood Hits	1113	Target Neighborhood Hits	112	Shared Neighborhood Hits	59
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

TNR22_MOUSE
NC score	0.061903 (rank : 935)	θ value	θ > 10 (rank : 1305)
Query Neighborhood Hits	1113	Target Neighborhood Hits	97	Shared Neighborhood Hits	50
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

ATS9_HUMAN
NC score	0.061821 (rank : 936)	θ value	θ > 10 (rank : 1128)
Query Neighborhood Hits	1113	Target Neighborhood Hits	219	Shared Neighborhood Hits	121
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

NETO1_MOUSE
NC score	0.061791 (rank : 937)	θ value	θ > 10 (rank : 1253)
Query Neighborhood Hits	1113	Target Neighborhood Hits	109	Shared Neighborhood Hits	61
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NOV_MOUSE
NC score	0.061552 (rank : 938)	θ value	4.03905 (rank : 999)
Query Neighborhood Hits	1113	Target Neighborhood Hits	130	Shared Neighborhood Hits	71
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

COEA1_HUMAN
NC score	0.061200 (rank : 939)	θ value	θ > 10 (rank : 1147)
Query Neighborhood Hits	1113	Target Neighborhood Hits	427	Shared Neighborhood Hits	62
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

WISP2_MOUSE
NC score	0.060875 (rank : 940)	θ value	θ > 10 (rank : 1327)
Query Neighborhood Hits	1113	Target Neighborhood Hits	129	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

PGCA_MOUSE
NC score	0.060688 (rank : 941)	θ value	θ > 10 (rank : 1265)
Query Neighborhood Hits	1113	Target Neighborhood Hits	643	Shared Neighborhood Hits	85
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

ATS7_HUMAN
NC score	0.060134 (rank : 942)	θ value	0.0961366 (rank : 680)
Query Neighborhood Hits	1113	Target Neighborhood Hits	169	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

GP115_MOUSE
NC score	0.060129 (rank : 943)	θ value	θ > 10 (rank : 1183)
Query Neighborhood Hits	1113	Target Neighborhood Hits	69	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D2L6	Gene names	Gpr115
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 precursor.

CSPG4_MOUSE
NC score	0.059853 (rank : 944)	θ value	θ > 10 (rank : 1160)
Query Neighborhood Hits	1113	Target Neighborhood Hits	105	Shared Neighborhood Hits	46
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

PRP2_MOUSE
NC score	0.059830 (rank : 945)	θ value	0.00665767 (rank : 577)
Query Neighborhood Hits	1113	Target Neighborhood Hits	347	Shared Neighborhood Hits	75
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

NETO2_HUMAN
NC score	0.059215 (rank : 946)	θ value	θ > 10 (rank : 1254)
Query Neighborhood Hits	1113	Target Neighborhood Hits	109	Shared Neighborhood Hits	59
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

CU081_HUMAN
NC score	0.059183 (rank : 947)	θ value	θ > 10 (rank : 1163)
Query Neighborhood Hits	1113	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

NETO2_MOUSE
NC score	0.059179 (rank : 948)	θ value	θ > 10 (rank : 1255)
Query Neighborhood Hits	1113	Target Neighborhood Hits	113	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

CSPG5_HUMAN
NC score	0.059136 (rank : 949)	θ value	θ > 10 (rank : 1161)
Query Neighborhood Hits	1113	Target Neighborhood Hits	199	Shared Neighborhood Hits	86
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

CSPG4_HUMAN
NC score	0.059015 (rank : 950)	θ value	θ > 10 (rank : 1159)
Query Neighborhood Hits	1113	Target Neighborhood Hits	112	Shared Neighborhood Hits	44
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

MT1E_HUMAN
NC score	0.058991 (rank : 951)	θ value	θ > 10 (rank : 1244)
Query Neighborhood Hits	1113	Target Neighborhood Hits	75	Shared Neighborhood Hits	55
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

GPR97_HUMAN
NC score	0.058740 (rank : 952)	θ value	θ > 10 (rank : 1196)
Query Neighborhood Hits	1113	Target Neighborhood Hits	86	Shared Neighborhood Hits	20
SwissProt Accessions	Q86Y34, Q6ZMF4, Q86SL9, Q8IZF1	Gene names	GPR97, PGR26
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor (G-protein coupled receptor PGR26).

GP115_HUMAN
NC score	0.058394 (rank : 953)	θ value	θ > 10 (rank : 1182)
Query Neighborhood Hits	1113	Target Neighborhood Hits	87	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IZF3, Q5T5B5, Q5T5B6, Q86SN9, Q8IXE6	Gene names	GPR115, PGR18
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 (G-protein coupled receptor PGR18).

TMG4_HUMAN
NC score	0.057997 (rank : 954)	θ value	θ > 10 (rank : 1289)
Query Neighborhood Hits	1113	Target Neighborhood Hits	31	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BZD6	Gene names	PRRG4, TMG4
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline- rich Gla protein 4) (Proline-rich gamma-carboxyglutamic acid protein 4).

TMG2_HUMAN
NC score	0.057697 (rank : 955)	θ value	θ > 10 (rank : 1285)
Query Neighborhood Hits	1113	Target Neighborhood Hits	25	Shared Neighborhood Hits	14
SwissProt Accessions	O14669	Gene names	PRRG2, PRGP2, TMG2
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 2 precursor (Proline- rich Gla protein 2) (Proline-rich gamma-carboxyglutamic acid protein 2).

DCBD1_HUMAN
NC score	0.057404 (rank : 956)	θ value	θ > 10 (rank : 1165)
Query Neighborhood Hits	1113	Target Neighborhood Hits	110	Shared Neighborhood Hits	44
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

CRDL1_MOUSE
NC score	0.057371 (rank : 957)	θ value	θ > 10 (rank : 1153)
Query Neighborhood Hits	1113	Target Neighborhood Hits	81	Shared Neighborhood Hits	51
SwissProt Accessions	Q920C1, Q924K0, Q9EPZ9	Gene names	Chrdl1, Ng1, Nrln1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

ATS20_MOUSE
NC score	0.057268 (rank : 958)	θ value	θ > 10 (rank : 1127)
Query Neighborhood Hits	1113	Target Neighborhood Hits	225	Shared Neighborhood Hits	113
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

WISP1_HUMAN
NC score	0.057006 (rank : 959)	θ value	θ > 10 (rank : 1324)
Query Neighborhood Hits	1113	Target Neighborhood Hits	121	Shared Neighborhood Hits	63
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

KREM1_MOUSE
NC score	0.056909 (rank : 960)	θ value	θ > 10 (rank : 1220)
Query Neighborhood Hits	1113	Target Neighborhood Hits	92	Shared Neighborhood Hits	43
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

MAGE1_HUMAN
NC score	0.056826 (rank : 961)	θ value	0.00298849 (rank : 547)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1389	Shared Neighborhood Hits	248
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

WISP1_MOUSE
NC score	0.056544 (rank : 962)	θ value	θ > 10 (rank : 1325)
Query Neighborhood Hits	1113	Target Neighborhood Hits	123	Shared Neighborhood Hits	58
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

CRDL1_HUMAN
NC score	0.056447 (rank : 963)	θ value	θ > 10 (rank : 1152)
Query Neighborhood Hits	1113	Target Neighborhood Hits	75	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BU40, Q9Y3H7	Gene names	CHRDL1, NRLN1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

GP111_HUMAN
NC score	0.056362 (rank : 964)	θ value	θ > 10 (rank : 1178)
Query Neighborhood Hits	1113	Target Neighborhood Hits	77	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IZF7, Q86SL6, Q8NGU5, Q8TDT5	Gene names	GPR111, PGR20
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 111 (G-protein coupled receptor PGR20).

GSCR1_HUMAN
NC score	0.056187 (rank : 965)	θ value	0.00390308 (rank : 552)
Query Neighborhood Hits	1113	Target Neighborhood Hits	674	Shared Neighborhood Hits	139
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

KR133_HUMAN
NC score	0.056167 (rank : 966)	θ value	θ > 10 (rank : 1214)
Query Neighborhood Hits	1113	Target Neighborhood Hits	66	Shared Neighborhood Hits	55
SwissProt Accessions	Q3SY46, Q3LI78	Gene names	KRTAP13-3, KAP13.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-3.

GP123_HUMAN
NC score	0.056166 (rank : 967)	θ value	θ > 10 (rank : 1184)
Query Neighborhood Hits	1113	Target Neighborhood Hits	120	Shared Neighborhood Hits	34
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

KR132_HUMAN
NC score	0.056112 (rank : 968)	θ value	θ > 10 (rank : 1213)
Query Neighborhood Hits	1113	Target Neighborhood Hits	69	Shared Neighborhood Hits	52
SwissProt Accessions	Q52LG2	Gene names	KRTAP13-2, KAP13.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-2.

THRB_HUMAN
NC score	0.056054 (rank : 969)	θ value	θ > 10 (rank : 1282)
Query Neighborhood Hits	1113	Target Neighborhood Hits	196	Shared Neighborhood Hits	43
SwissProt Accessions	P00734	Gene names	F2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

CFAB_HUMAN
NC score	0.055979 (rank : 970)	θ value	θ > 10 (rank : 1136)
Query Neighborhood Hits	1113	Target Neighborhood Hits	251	Shared Neighborhood Hits	63
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

TNR6B_HUMAN
NC score	0.055945 (rank : 971)	θ value	θ > 10 (rank : 1312)
Query Neighborhood Hits	1113	Target Neighborhood Hits	103	Shared Neighborhood Hits	48
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TNR6_MOUSE
NC score	0.055915 (rank : 972)	θ value	θ > 10 (rank : 1313)
Query Neighborhood Hits	1113	Target Neighborhood Hits	99	Shared Neighborhood Hits	53
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

KREM2_HUMAN
NC score	0.055682 (rank : 973)	θ value	θ > 10 (rank : 1221)
Query Neighborhood Hits	1113	Target Neighborhood Hits	93	Shared Neighborhood Hits	45
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

TMG2_MOUSE
NC score	0.055618 (rank : 974)	θ value	θ > 10 (rank : 1286)
Query Neighborhood Hits	1113	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R182, Q9EQI2	Gene names	Prrg2, N4wbp1
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 2 precursor (Proline- rich Gla protein 2) (Proline-rich gamma-carboxyglutamic acid protein 2) (NEDD4 WW domain-binding protein 1).

DCBD2_HUMAN
NC score	0.055571 (rank : 975)	θ value	θ > 10 (rank : 1166)
Query Neighborhood Hits	1113	Target Neighborhood Hits	118	Shared Neighborhood Hits	42
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

PROP_HUMAN
NC score	0.055537 (rank : 976)	θ value	θ > 10 (rank : 1267)
Query Neighborhood Hits	1113	Target Neighborhood Hits	126	Shared Neighborhood Hits	50
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

TMPS9_HUMAN
NC score	0.055503 (rank : 977)	θ value	θ > 10 (rank : 1296)
Query Neighborhood Hits	1113	Target Neighborhood Hits	276	Shared Neighborhood Hits	84
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

TMPS9_MOUSE
NC score	0.055396 (rank : 978)	θ value	θ > 10 (rank : 1297)
Query Neighborhood Hits	1113	Target Neighborhood Hits	296	Shared Neighborhood Hits	94
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

SPIT1_HUMAN
NC score	0.055300 (rank : 979)	θ value	θ > 10 (rank : 1278)
Query Neighborhood Hits	1113	Target Neighborhood Hits	100	Shared Neighborhood Hits	46
SwissProt Accessions	O43278, Q7Z7D2	Gene names	SPINT1, HAI1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

GPR98_HUMAN
NC score	0.055281 (rank : 980)	θ value	θ > 10 (rank : 1198)
Query Neighborhood Hits	1113	Target Neighborhood Hits	202	Shared Neighborhood Hits	38
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

TNR3_MOUSE
NC score	0.055170 (rank : 981)	θ value	θ > 10 (rank : 1308)
Query Neighborhood Hits	1113	Target Neighborhood Hits	113	Shared Neighborhood Hits	61
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

THRB_MOUSE
NC score	0.054620 (rank : 982)	θ value	θ > 10 (rank : 1283)
Query Neighborhood Hits	1113	Target Neighborhood Hits	195	Shared Neighborhood Hits	43
SwissProt Accessions	P19221	Gene names	F2, Cf2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

SPR2E_MOUSE
NC score	0.054526 (rank : 983)	θ value	0.47712 (rank : 788)
Query Neighborhood Hits	1113	Target Neighborhood Hits	45	Shared Neighborhood Hits	20
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

TRPC6_HUMAN
NC score	0.054214 (rank : 984)	θ value	0.47712 (rank : 790)
Query Neighborhood Hits	1113	Target Neighborhood Hits	171	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

LRP11_MOUSE
NC score	0.054175 (rank : 985)	θ value	θ > 10 (rank : 1237)
Query Neighborhood Hits	1113	Target Neighborhood Hits	81	Shared Neighborhood Hits	42
SwissProt Accessions	Q8CB67, Q8C7Y7	Gene names	Lrp11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

CO7A1_HUMAN
NC score	0.054139 (rank : 986)	θ value	θ > 10 (rank : 1144)
Query Neighborhood Hits	1113	Target Neighborhood Hits	807	Shared Neighborhood Hits	134
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

SPIT1_MOUSE
NC score	0.054079 (rank : 987)	θ value	θ > 10 (rank : 1279)
Query Neighborhood Hits	1113	Target Neighborhood Hits	96	Shared Neighborhood Hits	44
SwissProt Accessions	Q9R097	Gene names	Spint1, Hai1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

MUC1_HUMAN
NC score	0.054029 (rank : 988)	θ value	0.365318 (rank : 762)
Query Neighborhood Hits	1113	Target Neighborhood Hits	975	Shared Neighborhood Hits	225
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

KREM1_HUMAN
NC score	0.053948 (rank : 989)	θ value	θ > 10 (rank : 1219)
Query Neighborhood Hits	1113	Target Neighborhood Hits	90	Shared Neighborhood Hits	40
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

DCBD2_MOUSE
NC score	0.053806 (rank : 990)	θ value	θ > 10 (rank : 1167)
Query Neighborhood Hits	1113	Target Neighborhood Hits	113	Shared Neighborhood Hits	42
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

MUCDL_HUMAN
NC score	0.053720 (rank : 991)	θ value	θ > 10 (rank : 1251)
Query Neighborhood Hits	1113	Target Neighborhood Hits	777	Shared Neighborhood Hits	182
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

SEZ6L_HUMAN
NC score	0.053688 (rank : 992)	θ value	θ > 10 (rank : 1275)
Query Neighborhood Hits	1113	Target Neighborhood Hits	289	Shared Neighborhood Hits	109
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

TARSH_HUMAN
NC score	0.053626 (rank : 993)	θ value	3.0926 (rank : 970)
Query Neighborhood Hits	1113	Target Neighborhood Hits	768	Shared Neighborhood Hits	217
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

CO2_HUMAN
NC score	0.053232 (rank : 994)	θ value	θ > 10 (rank : 1142)
Query Neighborhood Hits	1113	Target Neighborhood Hits	258	Shared Neighborhood Hits	71
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CN032_HUMAN
NC score	0.053169 (rank : 995)	θ value	0.00134147 (rank : 520)
Query Neighborhood Hits	1113	Target Neighborhood Hits	267	Shared Neighborhood Hits	57
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

TNR6_HUMAN
NC score	0.053026 (rank : 996)	θ value	2.36792 (rank : 937)
Query Neighborhood Hits	1113	Target Neighborhood Hits	95	Shared Neighborhood Hits	48
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

WASF1_MOUSE
NC score	0.052991 (rank : 997)	θ value	1.38821 (rank : 883)
Query Neighborhood Hits	1113	Target Neighborhood Hits	261	Shared Neighborhood Hits	72
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

TMPS2_MOUSE
NC score	0.052888 (rank : 998)	θ value	θ > 10 (rank : 1291)
Query Neighborhood Hits	1113	Target Neighborhood Hits	243	Shared Neighborhood Hits	78
SwissProt Accessions	Q9JIQ8, Q9JKC4, Q9QY82	Gene names	Tmprss2
Domain Architecture
Description	Transmembrane protease, serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

RSPO1_HUMAN
NC score	0.052883 (rank : 999)	θ value	θ > 10 (rank : 1271)
Query Neighborhood Hits	1113	Target Neighborhood Hits	101	Shared Neighborhood Hits	56
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

GLU2B_HUMAN
NC score	0.052810 (rank : 1000)	θ value	θ > 10 (rank : 1175)
Query Neighborhood Hits	1113	Target Neighborhood Hits	377	Shared Neighborhood Hits	56
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

KREM2_MOUSE
NC score	0.052607 (rank : 1001)	θ value	θ > 10 (rank : 1222)
Query Neighborhood Hits	1113	Target Neighborhood Hits	90	Shared Neighborhood Hits	42
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

TNR1A_HUMAN
NC score	0.052528 (rank : 1002)	θ value	θ > 10 (rank : 1304)
Query Neighborhood Hits	1113	Target Neighborhood Hits	121	Shared Neighborhood Hits	52
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

GPR98_MOUSE
NC score	0.052387 (rank : 1003)	θ value	θ > 10 (rank : 1199)
Query Neighborhood Hits	1113	Target Neighborhood Hits	206	Shared Neighborhood Hits	36
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

SON_HUMAN
NC score	0.052197 (rank : 1004)	θ value	6.88961 (rank : 1072)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1568	Shared Neighborhood Hits	276
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

MT1F_HUMAN
NC score	0.052023 (rank : 1005)	θ value	θ > 10 (rank : 1245)
Query Neighborhood Hits	1113	Target Neighborhood Hits	73	Shared Neighborhood Hits	52
SwissProt Accessions	P04733, Q9UI97	Gene names	MT1F
Domain Architecture	No domain graphic available
Description	Metallothionein-1F (MT-1F) (Metallothionein-IF) (MT-IF).

NRX1B_HUMAN
NC score	0.051869 (rank : 1006)	θ value	θ > 10 (rank : 1261)
Query Neighborhood Hits	1113	Target Neighborhood Hits	37	Shared Neighborhood Hits	26
SwissProt Accessions	P58400	Gene names	NRXN1
Domain Architecture	No domain graphic available
Description	Neurexin-1-beta precursor (Neurexin I-beta).

TNR5_HUMAN
NC score	0.051811 (rank : 1007)	θ value	θ > 10 (rank : 1311)
Query Neighborhood Hits	1113	Target Neighborhood Hits	102	Shared Neighborhood Hits	53
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

ATS20_HUMAN
NC score	0.051794 (rank : 1008)	θ value	θ > 10 (rank : 1126)
Query Neighborhood Hits	1113	Target Neighborhood Hits	192	Shared Neighborhood Hits	98
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

KR221_HUMAN
NC score	0.051793 (rank : 1009)	θ value	θ > 10 (rank : 1216)
Query Neighborhood Hits	1113	Target Neighborhood Hits	6	Shared Neighborhood Hits	5
SwissProt Accessions	Q3MIV0	Gene names	KRTAP22-1, KAP22.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 22-1.

WASF3_MOUSE
NC score	0.051738 (rank : 1010)	θ value	0.00390308 (rank : 555)
Query Neighborhood Hits	1113	Target Neighborhood Hits	188	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

TMPS3_MOUSE
NC score	0.051539 (rank : 1011)	θ value	θ > 10 (rank : 1293)
Query Neighborhood Hits	1113	Target Neighborhood Hits	239	Shared Neighborhood Hits	72
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

TNR18_HUMAN
NC score	0.051262 (rank : 1012)	θ value	θ > 10 (rank : 1303)
Query Neighborhood Hits	1113	Target Neighborhood Hits	55	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

PI5PA_HUMAN
NC score	0.051261 (rank : 1013)	θ value	4.03905 (rank : 1001)
Query Neighborhood Hits	1113	Target Neighborhood Hits	749	Shared Neighborhood Hits	189
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

CUZD1_HUMAN
NC score	0.051234 (rank : 1014)	θ value	θ > 10 (rank : 1164)
Query Neighborhood Hits	1113	Target Neighborhood Hits	89	Shared Neighborhood Hits	35
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

LRP11_HUMAN
NC score	0.051186 (rank : 1015)	θ value	θ > 10 (rank : 1236)
Query Neighborhood Hits	1113	Target Neighborhood Hits	82	Shared Neighborhood Hits	39
SwissProt Accessions	Q86VZ4, Q5VYC0, Q96SN6	Gene names	LRP11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

SPR2F_MOUSE
NC score	0.051146 (rank : 1016)	θ value	0.0961366 (rank : 692)
Query Neighborhood Hits	1113	Target Neighborhood Hits	43	Shared Neighborhood Hits	19
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

TMG4_MOUSE
NC score	0.050946 (rank : 1017)	θ value	θ > 10 (rank : 1290)
Query Neighborhood Hits	1113	Target Neighborhood Hits	24	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BGN6, Q8BM25	Gene names	Prrg4, Tmg4
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline- rich Gla protein 4) (Proline-rich gamma-carboxyglutamic acid protein 4).

TMPS2_HUMAN
NC score	0.050938 (rank : 1018)	θ value	4.03905 (rank : 1008)
Query Neighborhood Hits	1113	Target Neighborhood Hits	252	Shared Neighborhood Hits	76
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

MFAP4_MOUSE
NC score	0.050910 (rank : 1019)	θ value	θ > 10 (rank : 1241)
Query Neighborhood Hits	1113	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D1H9, Q5NCN1	Gene names	Mfap4
Domain Architecture	No domain graphic available
Description	Microfibril-associated glycoprotein 4 precursor.

MFAP4_HUMAN
NC score	0.050849 (rank : 1020)	θ value	θ > 10 (rank : 1240)
Query Neighborhood Hits	1113	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	P55083, Q6P680	Gene names	MFAP4
Domain Architecture
Description	Microfibril-associated glycoprotein 4 precursor.

TMPS3_HUMAN
NC score	0.050744 (rank : 1021)	θ value	θ > 10 (rank : 1292)
Query Neighborhood Hits	1113	Target Neighborhood Hits	245	Shared Neighborhood Hits	70
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

CO2_MOUSE
NC score	0.050667 (rank : 1022)	θ value	θ > 10 (rank : 1143)
Query Neighborhood Hits	1113	Target Neighborhood Hits	250	Shared Neighborhood Hits	69
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

WASF1_HUMAN
NC score	0.050401 (rank : 1023)	θ value	3.0926 (rank : 973)
Query Neighborhood Hits	1113	Target Neighborhood Hits	260	Shared Neighborhood Hits	74
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

EPHB4_HUMAN
NC score	0.050364 (rank : 1024)	θ value	0.365318 (rank : 754)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1056	Shared Neighborhood Hits	183
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

SPRC_HUMAN
NC score	0.049319 (rank : 1025)	θ value	8.99809 (rank : 1107)
Query Neighborhood Hits	1113	Target Neighborhood Hits	45	Shared Neighborhood Hits	27
SwissProt Accessions	P09486	Gene names	SPARC, ON
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

RERE_MOUSE
NC score	0.048364 (rank : 1026)	θ value	9.29e-05 (rank : 472)
Query Neighborhood Hits	1113	Target Neighborhood Hits	785	Shared Neighborhood Hits	138
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

ATS6_HUMAN
NC score	0.047687 (rank : 1027)	θ value	8.99809 (rank : 1078)
Query Neighborhood Hits	1113	Target Neighborhood Hits	141	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

PDC6I_MOUSE
NC score	0.047630 (rank : 1028)	θ value	0.000461057 (rank : 502)
Query Neighborhood Hits	1113	Target Neighborhood Hits	275	Shared Neighborhood Hits	54
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

TNR1B_HUMAN
NC score	0.047516 (rank : 1029)	θ value	3.0926 (rank : 972)
Query Neighborhood Hits	1113	Target Neighborhood Hits	127	Shared Neighborhood Hits	62
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

PLMN_MOUSE
NC score	0.047168 (rank : 1030)	θ value	0.0961366 (rank : 689)
Query Neighborhood Hits	1113	Target Neighborhood Hits	208	Shared Neighborhood Hits	44
SwissProt Accessions	P20918, Q8CIS2, Q91WJ5	Gene names	Plg
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

OGFR_HUMAN
NC score	0.046802 (rank : 1031)	θ value	0.21417 (rank : 729)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1582	Shared Neighborhood Hits	262
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

CBP_MOUSE
NC score	0.046718 (rank : 1032)	θ value	0.0961366 (rank : 681)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1051	Shared Neighborhood Hits	217
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

ATS18_HUMAN
NC score	0.046474 (rank : 1033)	θ value	6.88961 (rank : 1058)
Query Neighborhood Hits	1113	Target Neighborhood Hits	169	Shared Neighborhood Hits	88
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

MLL2_HUMAN
NC score	0.046068 (rank : 1034)	θ value	4.03905 (rank : 996)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1788	Shared Neighborhood Hits	248
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

CBP_HUMAN
NC score	0.046047 (rank : 1035)	θ value	0.0148317 (rank : 603)
Query Neighborhood Hits	1113	Target Neighborhood Hits	941	Shared Neighborhood Hits	186
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

BSN_MOUSE
NC score	0.045856 (rank : 1036)	θ value	2.36792 (rank : 915)
Query Neighborhood Hits	1113	Target Neighborhood Hits	2057	Shared Neighborhood Hits	295
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

ASTL_HUMAN
NC score	0.045466 (rank : 1037)	θ value	2.36792 (rank : 913)
Query Neighborhood Hits	1113	Target Neighborhood Hits	252	Shared Neighborhood Hits	77
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

ATS16_MOUSE
NC score	0.045325 (rank : 1038)	θ value	6.88961 (rank : 1057)
Query Neighborhood Hits	1113	Target Neighborhood Hits	179	Shared Neighborhood Hits	92
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

MISS_MOUSE
NC score	0.045030 (rank : 1039)	θ value	8.99809 (rank : 1094)
Query Neighborhood Hits	1113	Target Neighborhood Hits	444	Shared Neighborhood Hits	146
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

ATN1_HUMAN
NC score	0.044958 (rank : 1040)	θ value	0.163984 (rank : 709)
Query Neighborhood Hits	1113	Target Neighborhood Hits	676	Shared Neighborhood Hits	115
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

WASF2_MOUSE
NC score	0.044860 (rank : 1041)	θ value	0.0193708 (rank : 626)
Query Neighborhood Hits	1113	Target Neighborhood Hits	315	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

INSRR_MOUSE
NC score	0.044845 (rank : 1042)	θ value	0.0193708 (rank : 620)
Query Neighborhood Hits	1113	Target Neighborhood Hits	961	Shared Neighborhood Hits	159
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

PRR12_HUMAN
NC score	0.044545 (rank : 1043)	θ value	0.0961366 (rank : 690)
Query Neighborhood Hits	1113	Target Neighborhood Hits	460	Shared Neighborhood Hits	94
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

SRRM1_MOUSE
NC score	0.044486 (rank : 1044)	θ value	0.365318 (rank : 768)
Query Neighborhood Hits	1113	Target Neighborhood Hits	966	Shared Neighborhood Hits	175
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

EP300_HUMAN
NC score	0.044299 (rank : 1045)	θ value	0.0148317 (rank : 607)
Query Neighborhood Hits	1113	Target Neighborhood Hits	821	Shared Neighborhood Hits	150
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

ATS13_MOUSE
NC score	0.044177 (rank : 1046)	θ value	0.125558 (rank : 696)
Query Neighborhood Hits	1113	Target Neighborhood Hits	227	Shared Neighborhood Hits	104
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

INSRR_HUMAN
NC score	0.044052 (rank : 1047)	θ value	0.0961366 (rank : 684)
Query Neighborhood Hits	1113	Target Neighborhood Hits	950	Shared Neighborhood Hits	147
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

SEM5A_HUMAN
NC score	0.043261 (rank : 1048)	θ value	0.21417 (rank : 732)
Query Neighborhood Hits	1113	Target Neighborhood Hits	177	Shared Neighborhood Hits	59
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

EZH1_MOUSE
NC score	0.043124 (rank : 1049)	θ value	0.62314 (rank : 797)
Query Neighborhood Hits	1113	Target Neighborhood Hits	126	Shared Neighborhood Hits	64
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

ARI1A_HUMAN
NC score	0.042977 (rank : 1050)	θ value	0.00509761 (rank : 557)
Query Neighborhood Hits	1113	Target Neighborhood Hits	787	Shared Neighborhood Hits	148
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

EZH1_HUMAN
NC score	0.042842 (rank : 1051)	θ value	0.365318 (rank : 756)
Query Neighborhood Hits	1113	Target Neighborhood Hits	121	Shared Neighborhood Hits	56
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

SPY1_HUMAN
NC score	0.042751 (rank : 1052)	θ value	3.0926 (rank : 968)
Query Neighborhood Hits	1113	Target Neighborhood Hits	64	Shared Neighborhood Hits	44
SwissProt Accessions	O43609, Q6PNE0	Gene names	SPRY1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

RERE_HUMAN
NC score	0.042500 (rank : 1053)	θ value	3.0926 (rank : 965)
Query Neighborhood Hits	1113	Target Neighborhood Hits	779	Shared Neighborhood Hits	144
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

SF3A2_MOUSE
NC score	0.042280 (rank : 1054)	θ value	1.06291 (rank : 855)
Query Neighborhood Hits	1113	Target Neighborhood Hits	247	Shared Neighborhood Hits	70
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

HGFL_MOUSE
NC score	0.041948 (rank : 1055)	θ value	5.27518 (rank : 1030)
Query Neighborhood Hits	1113	Target Neighborhood Hits	188	Shared Neighborhood Hits	42
SwissProt Accessions	P26928	Gene names	Mst1, Hgfl
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

WASF2_HUMAN
NC score	0.041339 (rank : 1056)	θ value	0.00509761 (rank : 565)
Query Neighborhood Hits	1113	Target Neighborhood Hits	280	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

F13B_MOUSE
NC score	0.041229 (rank : 1057)	θ value	1.81305 (rank : 888)
Query Neighborhood Hits	1113	Target Neighborhood Hits	93	Shared Neighborhood Hits	44
SwissProt Accessions	Q07968	Gene names	F13b, Cf13b
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain).

EZH2_MOUSE
NC score	0.041144 (rank : 1058)	θ value	0.365318 (rank : 758)
Query Neighborhood Hits	1113	Target Neighborhood Hits	86	Shared Neighborhood Hits	46
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

WASIP_MOUSE
NC score	0.040619 (rank : 1059)	θ value	1.38821 (rank : 884)
Query Neighborhood Hits	1113	Target Neighborhood Hits	392	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

WASF3_HUMAN
NC score	0.040564 (rank : 1060)	θ value	0.62314 (rank : 811)
Query Neighborhood Hits	1113	Target Neighborhood Hits	204	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

EZH2_HUMAN
NC score	0.040558 (rank : 1061)	θ value	0.365318 (rank : 757)
Query Neighborhood Hits	1113	Target Neighborhood Hits	84	Shared Neighborhood Hits	44
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

TYRP1_MOUSE
NC score	0.040434 (rank : 1062)	θ value	6.88961 (rank : 1075)
Query Neighborhood Hits	1113	Target Neighborhood Hits	43	Shared Neighborhood Hits	37
SwissProt Accessions	P07147	Gene names	Tyrp1, Tyrp-1
Domain Architecture
Description	5,6-dihydroxyindole-2-carboxylic acid oxidase precursor (EC 1.14.18.-) (DHICA oxidase) (Tyrosinase-related protein 1) (TRP-1) (TRP1) (TRP) (Catalase B) (Brown locus protein).

TRI42_MOUSE
NC score	0.040254 (rank : 1063)	θ value	0.62314 (rank : 808)
Query Neighborhood Hits	1113	Target Neighborhood Hits	316	Shared Neighborhood Hits	85
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

BAT2_HUMAN
NC score	0.039880 (rank : 1064)	θ value	0.21417 (rank : 723)
Query Neighborhood Hits	1113	Target Neighborhood Hits	931	Shared Neighborhood Hits	159
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

TCGAP_HUMAN
NC score	0.039811 (rank : 1065)	θ value	0.0148317 (rank : 613)
Query Neighborhood Hits	1113	Target Neighborhood Hits	872	Shared Neighborhood Hits	186
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

SETB1_MOUSE
NC score	0.039645 (rank : 1066)	θ value	0.62314 (rank : 805)
Query Neighborhood Hits	1113	Target Neighborhood Hits	150	Shared Neighborhood Hits	46
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

TRPC6_MOUSE
NC score	0.038692 (rank : 1067)	θ value	0.62314 (rank : 809)
Query Neighborhood Hits	1113	Target Neighborhood Hits	171	Shared Neighborhood Hits	90
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

SF3A2_HUMAN
NC score	0.038666 (rank : 1068)	θ value	0.279714 (rank : 746)
Query Neighborhood Hits	1113	Target Neighborhood Hits	263	Shared Neighborhood Hits	66
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

WASF4_HUMAN
NC score	0.038258 (rank : 1069)	θ value	0.125558 (rank : 706)
Query Neighborhood Hits	1113	Target Neighborhood Hits	282	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

S23IP_MOUSE
NC score	0.037894 (rank : 1070)	θ value	4.03905 (rank : 1002)
Query Neighborhood Hits	1113	Target Neighborhood Hits	363	Shared Neighborhood Hits	122
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

CN032_MOUSE
NC score	0.037719 (rank : 1071)	θ value	0.163984 (rank : 712)
Query Neighborhood Hits	1113	Target Neighborhood Hits	233	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

TYRP1_HUMAN
NC score	0.037227 (rank : 1072)	θ value	5.27518 (rank : 1049)
Query Neighborhood Hits	1113	Target Neighborhood Hits	40	Shared Neighborhood Hits	34
SwissProt Accessions	P17643, P78468, P78469, Q13721, Q15679	Gene names	TYRP1, CAS2, TYRP, TYRRP
Domain Architecture
Description	5,6-dihydroxyindole-2-carboxylic acid oxidase precursor (EC 1.14.18.-) (DHICA oxidase) (Tyrosinase-related protein 1) (TRP-1) (TRP1) (TRP) (Catalase B) (Glycoprotein 75) (Melanoma antigen gp75).

YLPM1_MOUSE
NC score	0.037126 (rank : 1073)	θ value	0.279714 (rank : 750)
Query Neighborhood Hits	1113	Target Neighborhood Hits	505	Shared Neighborhood Hits	84
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

HGF_MOUSE
NC score	0.037065 (rank : 1074)	θ value	8.99809 (rank : 1090)
Query Neighborhood Hits	1113	Target Neighborhood Hits	192	Shared Neighborhood Hits	40
SwissProt Accessions	Q08048, Q61662, Q64007, Q6LBE6	Gene names	Hgf
Domain Architecture
Description	Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain].

SC24C_HUMAN
NC score	0.036772 (rank : 1075)	θ value	2.36792 (rank : 929)
Query Neighborhood Hits	1113	Target Neighborhood Hits	662	Shared Neighborhood Hits	163
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

PCD15_HUMAN
NC score	0.036045 (rank : 1076)	θ value	0.62314 (rank : 804)
Query Neighborhood Hits	1113	Target Neighborhood Hits	289	Shared Neighborhood Hits	38
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

TNR1B_MOUSE
NC score	0.035978 (rank : 1077)	θ value	0.813845 (rank : 828)
Query Neighborhood Hits	1113	Target Neighborhood Hits	123	Shared Neighborhood Hits	51
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TAF4_HUMAN
NC score	0.035770 (rank : 1078)	θ value	1.38821 (rank : 881)
Query Neighborhood Hits	1113	Target Neighborhood Hits	687	Shared Neighborhood Hits	105
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

RAPH1_HUMAN
NC score	0.035448 (rank : 1079)	θ value	0.0431538 (rank : 651)
Query Neighborhood Hits	1113	Target Neighborhood Hits	593	Shared Neighborhood Hits	114
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

GGN_MOUSE
NC score	0.035385 (rank : 1080)	θ value	0.0961366 (rank : 683)
Query Neighborhood Hits	1113	Target Neighborhood Hits	311	Shared Neighborhood Hits	70
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

OC90_MOUSE
NC score	0.035086 (rank : 1081)	θ value	3.0926 (rank : 963)
Query Neighborhood Hits	1113	Target Neighborhood Hits	48	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z0L3, Q9CZ60, Q9Z225	Gene names	Oc90, Onc-95, Pla2ll
Domain Architecture
Description	Otoconin 90 precursor (Oc90) (Otoconin-95) (Oc95).

PCLO_HUMAN
NC score	0.034781 (rank : 1082)	θ value	1.38821 (rank : 874)
Query Neighborhood Hits	1113	Target Neighborhood Hits	2046	Shared Neighborhood Hits	262
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

BAT2_MOUSE
NC score	0.034566 (rank : 1083)	θ value	6.88961 (rank : 1059)
Query Neighborhood Hits	1113	Target Neighborhood Hits	947	Shared Neighborhood Hits	188
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

COL_HUMAN
NC score	0.034546 (rank : 1084)	θ value	1.06291 (rank : 838)
Query Neighborhood Hits	1113	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	P04118	Gene names	CLPS
Domain Architecture
Description	Colipase precursor.

TYRP2_HUMAN
NC score	0.034502 (rank : 1085)	θ value	0.813845 (rank : 831)
Query Neighborhood Hits	1113	Target Neighborhood Hits	42	Shared Neighborhood Hits	36
SwissProt Accessions	P40126	Gene names	DCT, TYRP2
Domain Architecture
Description	L-dopachrome tautomerase precursor (EC 5.3.3.12) (DT) (DCT) (L- dopachrome delta-isomerase) (Tyrosinase-related protein 2) (TRP-2) (TRP2).

MUC7_HUMAN
NC score	0.034439 (rank : 1086)	θ value	3.0926 (rank : 962)
Query Neighborhood Hits	1113	Target Neighborhood Hits	538	Shared Neighborhood Hits	99
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

PCD15_MOUSE
NC score	0.034085 (rank : 1087)	θ value	4.03905 (rank : 1000)
Query Neighborhood Hits	1113	Target Neighborhood Hits	262	Shared Neighborhood Hits	40
SwissProt Accessions	Q99PJ1	Gene names	Pcdh15
Domain Architecture
Description	Protocadherin-15 precursor.

PDC6I_HUMAN
NC score	0.034060 (rank : 1088)	θ value	1.06291 (rank : 850)
Query Neighborhood Hits	1113	Target Neighborhood Hits	278	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

SEM5B_HUMAN
NC score	0.033905 (rank : 1089)	θ value	1.06291 (rank : 854)
Query Neighborhood Hits	1113	Target Neighborhood Hits	178	Shared Neighborhood Hits	59
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

PRP1_HUMAN
NC score	0.033708 (rank : 1090)	θ value	1.06291 (rank : 852)
Query Neighborhood Hits	1113	Target Neighborhood Hits	385	Shared Neighborhood Hits	71
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

MNT_HUMAN
NC score	0.032384 (rank : 1091)	θ value	0.163984 (rank : 717)
Query Neighborhood Hits	1113	Target Neighborhood Hits	496	Shared Neighborhood Hits	124
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

CIC_HUMAN
NC score	0.032082 (rank : 1092)	θ value	0.279714 (rank : 738)
Query Neighborhood Hits	1113	Target Neighborhood Hits	992	Shared Neighborhood Hits	205
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CO039_MOUSE
NC score	0.031675 (rank : 1093)	θ value	4.03905 (rank : 983)
Query Neighborhood Hits	1113	Target Neighborhood Hits	445	Shared Neighborhood Hits	137
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

PRG4_HUMAN
NC score	0.031599 (rank : 1094)	θ value	1.81305 (rank : 903)
Query Neighborhood Hits	1113	Target Neighborhood Hits	764	Shared Neighborhood Hits	123
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PCLO_MOUSE
NC score	0.031336 (rank : 1095)	θ value	0.47712 (rank : 785)
Query Neighborhood Hits	1113	Target Neighborhood Hits	2275	Shared Neighborhood Hits	289
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

INSR_HUMAN
NC score	0.031017 (rank : 1096)	θ value	0.813845 (rank : 819)
Query Neighborhood Hits	1113	Target Neighborhood Hits	963	Shared Neighborhood Hits	143
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

IGF1R_MOUSE
NC score	0.030946 (rank : 1097)	θ value	1.06291 (rank : 842)
Query Neighborhood Hits	1113	Target Neighborhood Hits	973	Shared Neighborhood Hits	160
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

ZN207_HUMAN
NC score	0.030752 (rank : 1098)	θ value	4.03905 (rank : 1012)
Query Neighborhood Hits	1113	Target Neighborhood Hits	326	Shared Neighborhood Hits	51
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

CIC_MOUSE
NC score	0.030610 (rank : 1099)	θ value	0.0330416 (rank : 636)
Query Neighborhood Hits	1113	Target Neighborhood Hits	742	Shared Neighborhood Hits	156
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

YLPM1_HUMAN
NC score	0.030490 (rank : 1100)	θ value	8.99809 (rank : 1110)
Query Neighborhood Hits	1113	Target Neighborhood Hits	670	Shared Neighborhood Hits	121
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

DIAP1_HUMAN
NC score	0.030378 (rank : 1101)	θ value	0.00228821 (rank : 540)
Query Neighborhood Hits	1113	Target Neighborhood Hits	784	Shared Neighborhood Hits	85
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

NUMB_MOUSE
NC score	0.030286 (rank : 1102)	θ value	0.0431538 (rank : 650)
Query Neighborhood Hits	1113	Target Neighborhood Hits	91	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QZS3, P70422, Q8CIB1, Q9DC57, Q9QZR1, Q9QZS4	Gene names	Numb
Domain Architecture
Description	Protein numb homolog (m-Numb) (m-Nb).

FMN1A_MOUSE
NC score	0.030283 (rank : 1103)	θ value	0.0330416 (rank : 637)
Query Neighborhood Hits	1113	Target Neighborhood Hits	423	Shared Neighborhood Hits	74
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

ALEX_HUMAN
NC score	0.030273 (rank : 1104)	θ value	1.81305 (rank : 885)
Query Neighborhood Hits	1113	Target Neighborhood Hits	361	Shared Neighborhood Hits	92
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

GFRAL_MOUSE
NC score	0.030255 (rank : 1105)	θ value	0.47712 (rank : 781)
Query Neighborhood Hits	1113	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	Q6SJE0, Q6SJD9	Gene names	Gfral, Gral
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-like precursor.

SYN1_HUMAN
NC score	0.030207 (rank : 1106)	θ value	0.279714 (rank : 747)
Query Neighborhood Hits	1113	Target Neighborhood Hits	419	Shared Neighborhood Hits	89
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

RBM12_HUMAN
NC score	0.029764 (rank : 1107)	θ value	0.0431538 (rank : 652)
Query Neighborhood Hits	1113	Target Neighborhood Hits	298	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

DIAP1_MOUSE
NC score	0.029755 (rank : 1108)	θ value	0.0113563 (rank : 595)
Query Neighborhood Hits	1113	Target Neighborhood Hits	839	Shared Neighborhood Hits	83
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

DCC_HUMAN
NC score	0.029717 (rank : 1109)	θ value	8.99809 (rank : 1082)
Query Neighborhood Hits	1113	Target Neighborhood Hits	583	Shared Neighborhood Hits	94
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

GP1BA_HUMAN
NC score	0.029669 (rank : 1110)	θ value	1.81305 (rank : 889)
Query Neighborhood Hits	1113	Target Neighborhood Hits	407	Shared Neighborhood Hits	49
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

NEO1_HUMAN
NC score	0.029547 (rank : 1111)	θ value	8.99809 (rank : 1098)
Query Neighborhood Hits	1113	Target Neighborhood Hits	530	Shared Neighborhood Hits	54
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

EPHA7_HUMAN
NC score	0.029438 (rank : 1112)	θ value	6.88961 (rank : 1063)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1053	Shared Neighborhood Hits	163
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

SAPS1_HUMAN
NC score	0.029276 (rank : 1113)	θ value	2.36792 (rank : 928)
Query Neighborhood Hits	1113	Target Neighborhood Hits	704	Shared Neighborhood Hits	168
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

MINT_MOUSE
NC score	0.028969 (rank : 1114)	θ value	0.0961366 (rank : 687)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1514	Shared Neighborhood Hits	219
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NSD1_MOUSE
NC score	0.028788 (rank : 1115)	θ value	8.99809 (rank : 1099)
Query Neighborhood Hits	1113	Target Neighborhood Hits	472	Shared Neighborhood Hits	86
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PRG4_MOUSE
NC score	0.028602 (rank : 1116)	θ value	6.88961 (rank : 1068)
Query Neighborhood Hits	1113	Target Neighborhood Hits	624	Shared Neighborhood Hits	100
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SF3A1_MOUSE
NC score	0.028555 (rank : 1117)	θ value	0.0736092 (rank : 678)
Query Neighborhood Hits	1113	Target Neighborhood Hits	198	Shared Neighborhood Hits	39
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

SRRM1_HUMAN
NC score	0.028203 (rank : 1118)	θ value	1.06291 (rank : 856)
Query Neighborhood Hits	1113	Target Neighborhood Hits	690	Shared Neighborhood Hits	97
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SF3A1_HUMAN
NC score	0.028018 (rank : 1119)	θ value	0.0961366 (rank : 691)
Query Neighborhood Hits	1113	Target Neighborhood Hits	199	Shared Neighborhood Hits	44
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

CPSF6_MOUSE
NC score	0.027455 (rank : 1120)	θ value	1.38821 (rank : 863)
Query Neighborhood Hits	1113	Target Neighborhood Hits	356	Shared Neighborhood Hits	62
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

INSR_MOUSE
NC score	0.027455 (rank : 1121)	θ value	0.279714 (rank : 741)
Query Neighborhood Hits	1113	Target Neighborhood Hits	968	Shared Neighborhood Hits	140
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

CPSF6_HUMAN
NC score	0.027374 (rank : 1122)	θ value	1.38821 (rank : 862)
Query Neighborhood Hits	1113	Target Neighborhood Hits	359	Shared Neighborhood Hits	62
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

EPHB6_HUMAN
NC score	0.027360 (rank : 1123)	θ value	1.81305 (rank : 887)
Query Neighborhood Hits	1113	Target Neighborhood Hits	912	Shared Neighborhood Hits	137
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

IGF1R_HUMAN
NC score	0.027149 (rank : 1124)	θ value	0.279714 (rank : 740)
Query Neighborhood Hits	1113	Target Neighborhood Hits	977	Shared Neighborhood Hits	160
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

FHR3_HUMAN
NC score	0.027081 (rank : 1125)	θ value	0.62314 (rank : 798)
Query Neighborhood Hits	1113	Target Neighborhood Hits	74	Shared Neighborhood Hits	33
SwissProt Accessions	Q02985, Q9UJ16	Gene names	CFHL3, FHR3
Domain Architecture
Description	Complement factor H-related protein 3 precursor (FHR-3) (H factor-like protein 3) (DOWN16).

RBM12_MOUSE
NC score	0.026821 (rank : 1126)	θ value	0.0431538 (rank : 653)
Query Neighborhood Hits	1113	Target Neighborhood Hits	313	Shared Neighborhood Hits	52
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

EMID2_MOUSE
NC score	0.026763 (rank : 1127)	θ value	6.88961 (rank : 1062)
Query Neighborhood Hits	1113	Target Neighborhood Hits	201	Shared Neighborhood Hits	50
SwissProt Accessions	Q91VF6, Q8K4P3	Gene names	Emid2, Col26a, Col26a1, Emu2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

SRRM2_MOUSE
NC score	0.026577 (rank : 1128)	θ value	3.0926 (rank : 969)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1470	Shared Neighborhood Hits	187
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

PRR13_HUMAN
NC score	0.026479 (rank : 1129)	θ value	3.0926 (rank : 964)
Query Neighborhood Hits	1113	Target Neighborhood Hits	105	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

SRRM2_HUMAN
NC score	0.026474 (rank : 1130)	θ value	1.38821 (rank : 879)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1296	Shared Neighborhood Hits	160
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

K1802_MOUSE
NC score	0.026406 (rank : 1131)	θ value	1.38821 (rank : 869)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1596	Shared Neighborhood Hits	238
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

FMN1B_MOUSE
NC score	0.026261 (rank : 1132)	θ value	0.0330416 (rank : 638)
Query Neighborhood Hits	1113	Target Neighborhood Hits	447	Shared Neighborhood Hits	70
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

SPRL1_MOUSE
NC score	0.026125 (rank : 1133)	θ value	4.03905 (rank : 1007)
Query Neighborhood Hits	1113	Target Neighborhood Hits	403	Shared Neighborhood Hits	45
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

BRD4_MOUSE
NC score	0.025716 (rank : 1134)	θ value	0.0563607 (rank : 660)
Query Neighborhood Hits	1113	Target Neighborhood Hits	845	Shared Neighborhood Hits	108
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

MN1_HUMAN
NC score	0.025082 (rank : 1135)	θ value	2.36792 (rank : 923)
Query Neighborhood Hits	1113	Target Neighborhood Hits	196	Shared Neighborhood Hits	41
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

SMRC1_HUMAN
NC score	0.025049 (rank : 1136)	θ value	1.38821 (rank : 878)
Query Neighborhood Hits	1113	Target Neighborhood Hits	375	Shared Neighborhood Hits	57
SwissProt Accessions	Q92922, Q6P172, Q8IWH2	Gene names	SMARCC1, BAF155
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155).

T22D2_HUMAN
NC score	0.024801 (rank : 1137)	θ value	0.279714 (rank : 748)
Query Neighborhood Hits	1113	Target Neighborhood Hits	250	Shared Neighborhood Hits	57
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

PI5PA_MOUSE
NC score	0.024589 (rank : 1138)	θ value	2.36792 (rank : 926)
Query Neighborhood Hits	1113	Target Neighborhood Hits	331	Shared Neighborhood Hits	86
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

NUMB_HUMAN
NC score	0.024513 (rank : 1139)	θ value	0.279714 (rank : 745)
Query Neighborhood Hits	1113	Target Neighborhood Hits	112	Shared Neighborhood Hits	36
SwissProt Accessions	P49757, Q6NUQ7, Q86SY1, Q8WW73, Q9UBG1, Q9UEQ4, Q9UKE8, Q9UKE9, Q9UKF0, Q9UQJ4	Gene names	NUMB
Domain Architecture
Description	Protein numb homolog (h-Numb) (Protein S171).

DIDO1_HUMAN
NC score	0.024499 (rank : 1140)	θ value	0.21417 (rank : 725)
Query Neighborhood Hits	1113	Target Neighborhood Hits	960	Shared Neighborhood Hits	152
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

TF7L2_HUMAN
NC score	0.024495 (rank : 1141)	θ value	0.0431538 (rank : 655)
Query Neighborhood Hits	1113	Target Neighborhood Hits	119	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NQB0, O00185, Q9NQB1, Q9NQB2, Q9NQB3, Q9NQB4, Q9NQB5, Q9NQB6, Q9NQB7, Q9ULC2	Gene names	TCF7L2, TCF4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (hTCF-4).

MMRN2_HUMAN
NC score	0.024180 (rank : 1142)	θ value	8.99809 (rank : 1095)
Query Neighborhood Hits	1113	Target Neighborhood Hits	400	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H8L6, Q6P2N2	Gene names	MMRN2, EMILIN3
Domain Architecture
Description	Multimerin-2 precursor (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit).

WASL_HUMAN
NC score	0.023933 (rank : 1143)	θ value	6.88961 (rank : 1076)
Query Neighborhood Hits	1113	Target Neighborhood Hits	312	Shared Neighborhood Hits	74
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

DMRTD_HUMAN
NC score	0.023645 (rank : 1144)	θ value	8.99809 (rank : 1086)
Query Neighborhood Hits	1113	Target Neighborhood Hits	216	Shared Neighborhood Hits	89
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

TITIN_HUMAN
NC score	0.023518 (rank : 1145)	θ value	0.813845 (rank : 827)
Query Neighborhood Hits	1113	Target Neighborhood Hits	2923	Shared Neighborhood Hits	232
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

K1683_HUMAN
NC score	0.023367 (rank : 1146)	θ value	4.03905 (rank : 995)
Query Neighborhood Hits	1113	Target Neighborhood Hits	240	Shared Neighborhood Hits	78
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

SF01_HUMAN
NC score	0.023316 (rank : 1147)	θ value	0.365318 (rank : 766)
Query Neighborhood Hits	1113	Target Neighborhood Hits	287	Shared Neighborhood Hits	68
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

HRX_HUMAN
NC score	0.023159 (rank : 1148)	θ value	1.38821 (rank : 868)
Query Neighborhood Hits	1113	Target Neighborhood Hits	825	Shared Neighborhood Hits	110
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

MINT_HUMAN
NC score	0.022947 (rank : 1149)	θ value	0.21417 (rank : 728)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1291	Shared Neighborhood Hits	157
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SMRC1_MOUSE
NC score	0.022921 (rank : 1150)	θ value	0.21417 (rank : 733)
Query Neighborhood Hits	1113	Target Neighborhood Hits	459	Shared Neighborhood Hits	57
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

TRI42_HUMAN
NC score	0.022781 (rank : 1151)	θ value	4.03905 (rank : 1010)
Query Neighborhood Hits	1113	Target Neighborhood Hits	283	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

MNT_MOUSE
NC score	0.022737 (rank : 1152)	θ value	3.0926 (rank : 960)
Query Neighborhood Hits	1113	Target Neighborhood Hits	432	Shared Neighborhood Hits	93
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

PER1_MOUSE
NC score	0.022632 (rank : 1153)	θ value	1.38821 (rank : 875)
Query Neighborhood Hits	1113	Target Neighborhood Hits	235	Shared Neighborhood Hits	59
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

PER3_HUMAN
NC score	0.022624 (rank : 1154)	θ value	8.99809 (rank : 1100)
Query Neighborhood Hits	1113	Target Neighborhood Hits	479	Shared Neighborhood Hits	123
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

CRTC1_HUMAN
NC score	0.022576 (rank : 1155)	θ value	1.38821 (rank : 864)
Query Neighborhood Hits	1113	Target Neighborhood Hits	319	Shared Neighborhood Hits	87
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

ENAH_MOUSE
NC score	0.022538 (rank : 1156)	θ value	0.0563607 (rank : 664)
Query Neighborhood Hits	1113	Target Neighborhood Hits	919	Shared Neighborhood Hits	118
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

SPR2G_HUMAN
NC score	0.022491 (rank : 1157)	θ value	8.99809 (rank : 1106)
Query Neighborhood Hits	1113	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BYE4	Gene names	SPRR2G
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G (SPR-2G).

ERBB3_HUMAN
NC score	0.022389 (rank : 1158)	θ value	0.62314 (rank : 795)
Query Neighborhood Hits	1113	Target Neighborhood Hits	918	Shared Neighborhood Hits	137
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

WASL_MOUSE
NC score	0.022298 (rank : 1159)	θ value	1.81305 (rank : 907)
Query Neighborhood Hits	1113	Target Neighborhood Hits	339	Shared Neighborhood Hits	72
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

BRD4_HUMAN
NC score	0.022282 (rank : 1160)	θ value	1.38821 (rank : 860)
Query Neighborhood Hits	1113	Target Neighborhood Hits	851	Shared Neighborhood Hits	110
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

FMNL_HUMAN
NC score	0.022173 (rank : 1161)	θ value	4.03905 (rank : 989)
Query Neighborhood Hits	1113	Target Neighborhood Hits	529	Shared Neighborhood Hits	75
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

TAB3_MOUSE
NC score	0.022058 (rank : 1162)	θ value	0.47712 (rank : 789)
Query Neighborhood Hits	1113	Target Neighborhood Hits	273	Shared Neighborhood Hits	72
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

SYN1_MOUSE
NC score	0.022043 (rank : 1163)	θ value	0.813845 (rank : 825)
Query Neighborhood Hits	1113	Target Neighborhood Hits	363	Shared Neighborhood Hits	81
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

DAG1_HUMAN
NC score	0.021965 (rank : 1164)	θ value	5.27518 (rank : 1020)
Query Neighborhood Hits	1113	Target Neighborhood Hits	104	Shared Neighborhood Hits	38
SwissProt Accessions	Q14118	Gene names	DAG1
Domain Architecture
Description	Dystroglycan precursor (Dystrophin-associated glycoprotein 1) [Contains: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta- DG)].

BCAR1_MOUSE
NC score	0.021853 (rank : 1165)	θ value	0.0330416 (rank : 635)
Query Neighborhood Hits	1113	Target Neighborhood Hits	438	Shared Neighborhood Hits	111
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

PER1_HUMAN
NC score	0.021676 (rank : 1166)	θ value	0.00509761 (rank : 562)
Query Neighborhood Hits	1113	Target Neighborhood Hits	215	Shared Neighborhood Hits	50
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

MUC1_MOUSE
NC score	0.021592 (rank : 1167)	θ value	4.03905 (rank : 997)
Query Neighborhood Hits	1113	Target Neighborhood Hits	388	Shared Neighborhood Hits	66
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

SF01_MOUSE
NC score	0.021519 (rank : 1168)	θ value	0.47712 (rank : 787)
Query Neighborhood Hits	1113	Target Neighborhood Hits	240	Shared Neighborhood Hits	57
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

DOT1L_HUMAN
NC score	0.021287 (rank : 1169)	θ value	5.27518 (rank : 1021)
Query Neighborhood Hits	1113	Target Neighborhood Hits	660	Shared Neighborhood Hits	95
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

MTSS1_HUMAN
NC score	0.021256 (rank : 1170)	θ value	8.99809 (rank : 1096)
Query Neighborhood Hits	1113	Target Neighborhood Hits	504	Shared Neighborhood Hits	102
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

NSD1_HUMAN
NC score	0.020911 (rank : 1171)	θ value	5.27518 (rank : 1043)
Query Neighborhood Hits	1113	Target Neighborhood Hits	427	Shared Neighborhood Hits	76
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

CCNK_MOUSE
NC score	0.020393 (rank : 1172)	θ value	0.21417 (rank : 724)
Query Neighborhood Hits	1113	Target Neighborhood Hits	350	Shared Neighborhood Hits	64
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

HYAL2_HUMAN
NC score	0.020340 (rank : 1173)	θ value	5.27518 (rank : 1031)
Query Neighborhood Hits	1113	Target Neighborhood Hits	24	Shared Neighborhood Hits	16
SwissProt Accessions	Q12891, O15177, Q9BW29	Gene names	HYAL2, LUCA2
Domain Architecture
Description	Hyaluronidase-2 precursor (EC 3.2.1.35) (Hyal-2) (Hyaluronoglucosaminidase-2) (LUCA-2).

CHCH2_HUMAN
NC score	0.019955 (rank : 1174)	θ value	0.62314 (rank : 793)
Query Neighborhood Hits	1113	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6H1, Q6NZ50	Gene names	CHCHD2
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 (HCV NS2 trans-regulated protein) (NS2TP).

IMPG1_MOUSE
NC score	0.019946 (rank : 1175)	θ value	3.0926 (rank : 955)
Query Neighborhood Hits	1113	Target Neighborhood Hits	50	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R1W8, Q9CTP8, Q9ES62, Q9ET31	Gene names	Impg1, Spacr
Domain Architecture	No domain graphic available
Description	Interphotoreceptor matrix proteoglycan 1 precursor (IPM 150 proteoglycan) (Sialoprotein associated with cones and rods).

F19A1_MOUSE
NC score	0.019494 (rank : 1176)	θ value	2.36792 (rank : 917)
Query Neighborhood Hits	1113	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TPG8	Gene names	Fam19a1, Tafa1
Domain Architecture	No domain graphic available
Description	Protein FAM19A1 precursor (Chemokine-like protein TAFA-1).

F19A1_HUMAN
NC score	0.019473 (rank : 1177)	θ value	2.36792 (rank : 916)
Query Neighborhood Hits	1113	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z5A9, Q8TCL8	Gene names	FAM19A1, TAFA1
Domain Architecture	No domain graphic available
Description	Protein FAM19A1 precursor (Chemokine-like protein TAFA-1).

SFR15_HUMAN
NC score	0.019258 (rank : 1178)	θ value	3.0926 (rank : 966)
Query Neighborhood Hits	1113	Target Neighborhood Hits	368	Shared Neighborhood Hits	64
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

PTN23_HUMAN
NC score	0.019213 (rank : 1179)	θ value	0.0148317 (rank : 611)
Query Neighborhood Hits	1113	Target Neighborhood Hits	646	Shared Neighborhood Hits	97
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

MAML1_MOUSE
NC score	0.019101 (rank : 1180)	θ value	1.06291 (rank : 847)
Query Neighborhood Hits	1113	Target Neighborhood Hits	279	Shared Neighborhood Hits	65
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

TROAP_HUMAN
NC score	0.019014 (rank : 1181)	θ value	5.27518 (rank : 1048)
Query Neighborhood Hits	1113	Target Neighborhood Hits	258	Shared Neighborhood Hits	74
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

EPHAA_HUMAN
NC score	0.018832 (rank : 1182)	θ value	4.03905 (rank : 987)
Query Neighborhood Hits	1113	Target Neighborhood Hits	960	Shared Neighborhood Hits	114
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

DSG1C_MOUSE
NC score	0.018739 (rank : 1183)	θ value	4.03905 (rank : 986)
Query Neighborhood Hits	1113	Target Neighborhood Hits	156	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TSF0, Q7TQ61	Gene names	Dsg1c, Dsg6
Domain Architecture	No domain graphic available
Description	Desmoglein-1 gamma precursor (Dsg1-gamma) (Desmoglein-6).

RC3H1_HUMAN
NC score	0.018728 (rank : 1184)	θ value	0.365318 (rank : 764)
Query Neighborhood Hits	1113	Target Neighborhood Hits	433	Shared Neighborhood Hits	97
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

CDN1C_HUMAN
NC score	0.018604 (rank : 1185)	θ value	4.03905 (rank : 981)
Query Neighborhood Hits	1113	Target Neighborhood Hits	168	Shared Neighborhood Hits	37
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

NCA11_MOUSE
NC score	0.018337 (rank : 1186)	θ value	1.06291 (rank : 848)
Query Neighborhood Hits	1113	Target Neighborhood Hits	661	Shared Neighborhood Hits	78
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

ANTR1_HUMAN
NC score	0.018246 (rank : 1187)	θ value	3.0926 (rank : 943)
Query Neighborhood Hits	1113	Target Neighborhood Hits	128	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H6X2, Q96P02, Q9NVP3	Gene names	ANTXR1, ATR, TEM8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

EPN3_HUMAN
NC score	0.018222 (rank : 1188)	θ value	0.47712 (rank : 779)
Query Neighborhood Hits	1113	Target Neighborhood Hits	197	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

PRRT3_MOUSE
NC score	0.018196 (rank : 1189)	θ value	8.99809 (rank : 1102)
Query Neighborhood Hits	1113	Target Neighborhood Hits	162	Shared Neighborhood Hits	28
SwissProt Accessions	Q6PE13	Gene names	Prrt3
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

NFAC1_HUMAN
NC score	0.017828 (rank : 1190)	θ value	5.27518 (rank : 1042)
Query Neighborhood Hits	1113	Target Neighborhood Hits	312	Shared Neighborhood Hits	101
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

ZIM10_MOUSE
NC score	0.017660 (rank : 1191)	θ value	5.27518 (rank : 1054)
Query Neighborhood Hits	1113	Target Neighborhood Hits	430	Shared Neighborhood Hits	109
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

SFPQ_MOUSE
NC score	0.017495 (rank : 1192)	θ value	0.813845 (rank : 823)
Query Neighborhood Hits	1113	Target Neighborhood Hits	958	Shared Neighborhood Hits	104
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

GNDS_MOUSE
NC score	0.017169 (rank : 1193)	θ value	0.0113563 (rank : 596)
Query Neighborhood Hits	1113	Target Neighborhood Hits	115	Shared Neighborhood Hits	21
SwissProt Accessions	Q03385	Gene names	Ralgds, Rgds
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

ANTR1_MOUSE
NC score	0.016637 (rank : 1194)	θ value	2.36792 (rank : 912)
Query Neighborhood Hits	1113	Target Neighborhood Hits	143	Shared Neighborhood Hits	43
SwissProt Accessions	Q9CZ52	Gene names	Antxr1, Atr, Tem8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

SOX30_HUMAN
NC score	0.016556 (rank : 1195)	θ value	0.813845 (rank : 824)
Query Neighborhood Hits	1113	Target Neighborhood Hits	305	Shared Neighborhood Hits	84
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

ROBO3_MOUSE
NC score	0.016502 (rank : 1196)	θ value	6.88961 (rank : 1070)
Query Neighborhood Hits	1113	Target Neighborhood Hits	524	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

TINAL_MOUSE
NC score	0.016419 (rank : 1197)	θ value	8.99809 (rank : 1108)
Query Neighborhood Hits	1113	Target Neighborhood Hits	52	Shared Neighborhood Hits	21
SwissProt Accessions	Q99JR5, Q9EQT9	Gene names	Tinagl1, Arg1, Lcn7, Tinagl
Domain Architecture	No domain graphic available
Description	Tubulointerstitial nephritis antigen-like precursor (Androgen- regulated gene 1 protein) (Adrenocortical zonation factor 1) (AZ-1) (Tubulointerstitial nephritis antigen-related protein) (TARP).

IL4RA_HUMAN
NC score	0.016055 (rank : 1198)	θ value	6.88961 (rank : 1064)
Query Neighborhood Hits	1113	Target Neighborhood Hits	144	Shared Neighborhood Hits	41
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

PTN23_MOUSE
NC score	0.015695 (rank : 1199)	θ value	2.36792 (rank : 927)
Query Neighborhood Hits	1113	Target Neighborhood Hits	726	Shared Neighborhood Hits	124
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

ATX2L_HUMAN
NC score	0.015581 (rank : 1200)	θ value	8.99809 (rank : 1079)
Query Neighborhood Hits	1113	Target Neighborhood Hits	443	Shared Neighborhood Hits	100
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

PHLPP_HUMAN
NC score	0.015229 (rank : 1201)	θ value	8.99809 (rank : 1101)
Query Neighborhood Hits	1113	Target Neighborhood Hits	604	Shared Neighborhood Hits	77
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

NCOR2_MOUSE
NC score	0.015177 (rank : 1202)	θ value	1.06291 (rank : 849)
Query Neighborhood Hits	1113	Target Neighborhood Hits	790	Shared Neighborhood Hits	117
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

SYNJ1_MOUSE
NC score	0.015096 (rank : 1203)	θ value	5.27518 (rank : 1047)
Query Neighborhood Hits	1113	Target Neighborhood Hits	516	Shared Neighborhood Hits	126
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

AUTS2_HUMAN
NC score	0.014913 (rank : 1204)	θ value	2.36792 (rank : 914)
Query Neighborhood Hits	1113	Target Neighborhood Hits	342	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

SF3B1_MOUSE
NC score	0.014907 (rank : 1205)	θ value	5.27518 (rank : 1046)
Query Neighborhood Hits	1113	Target Neighborhood Hits	352	Shared Neighborhood Hits	70
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

IF35_MOUSE
NC score	0.014683 (rank : 1206)	θ value	3.0926 (rank : 954)
Query Neighborhood Hits	1113	Target Neighborhood Hits	210	Shared Neighborhood Hits	45
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

AMOT_HUMAN
NC score	0.014654 (rank : 1207)	θ value	2.36792 (rank : 911)
Query Neighborhood Hits	1113	Target Neighborhood Hits	712	Shared Neighborhood Hits	84
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

SF3B1_HUMAN
NC score	0.014629 (rank : 1208)	θ value	5.27518 (rank : 1045)
Query Neighborhood Hits	1113	Target Neighborhood Hits	341	Shared Neighborhood Hits	68
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

N4BP2_HUMAN
NC score	0.014587 (rank : 1209)	θ value	1.81305 (rank : 899)
Query Neighborhood Hits	1113	Target Neighborhood Hits	107	Shared Neighborhood Hits	13
SwissProt Accessions	Q86UW6, Q9NVK2, Q9P2D4	Gene names	N4BP2, B3BP, KIAA1413
Domain Architecture
Description	NEDD4-binding protein 2 (EC 3.-.-.-) (N4BP2) (BCL-3-binding protein).

CD2_MOUSE
NC score	0.014465 (rank : 1210)	θ value	1.38821 (rank : 861)
Query Neighborhood Hits	1113	Target Neighborhood Hits	45	Shared Neighborhood Hits	16
SwissProt Accessions	P08920, Q61394	Gene names	Cd2, Ly-37
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Lymphocyte antigen Ly-37).

SOX30_MOUSE
NC score	0.014370 (rank : 1211)	θ value	4.03905 (rank : 1006)
Query Neighborhood Hits	1113	Target Neighborhood Hits	374	Shared Neighborhood Hits	100
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

K0460_MOUSE
NC score	0.014348 (rank : 1212)	θ value	8.99809 (rank : 1091)
Query Neighborhood Hits	1113	Target Neighborhood Hits	374	Shared Neighborhood Hits	62
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

RFX1_HUMAN
NC score	0.013972 (rank : 1213)	θ value	1.81305 (rank : 904)
Query Neighborhood Hits	1113	Target Neighborhood Hits	256	Shared Neighborhood Hits	59
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

ZCH14_MOUSE
NC score	0.013524 (rank : 1214)	θ value	8.99809 (rank : 1111)
Query Neighborhood Hits	1113	Target Neighborhood Hits	109	Shared Neighborhood Hits	31
SwissProt Accessions	Q8VIG0, Q80TX3, Q91VU4	Gene names	Zcchc14, Kiaa0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

TINAL_HUMAN
NC score	0.013371 (rank : 1215)	θ value	6.88961 (rank : 1074)
Query Neighborhood Hits	1113	Target Neighborhood Hits	50	Shared Neighborhood Hits	21
SwissProt Accessions	Q9GZM7, Q8TEJ9, Q8WZ23, Q96GZ4, Q96JW3	Gene names	TINAGL1, GIS5, LCN7, OLRG2, TINAGL
Domain Architecture	No domain graphic available
Description	Tubulointerstitial nephritis antigen-like precursor (Tubulointerstitial nephritis antigen-related protein) (TIN Ag-related protein) (TIN-Ag-RP) (Glucocorticoid-inducible protein 5) (Oxidized LDL-responsive gene 2 protein) (OLRG-2).

DAB2_MOUSE
NC score	0.013187 (rank : 1216)	θ value	4.03905 (rank : 984)
Query Neighborhood Hits	1113	Target Neighborhood Hits	163	Shared Neighborhood Hits	43
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

SMRC2_HUMAN
NC score	0.013181 (rank : 1217)	θ value	4.03905 (rank : 1005)
Query Neighborhood Hits	1113	Target Neighborhood Hits	499	Shared Neighborhood Hits	62
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SFPQ_HUMAN
NC score	0.013174 (rank : 1218)	θ value	0.62314 (rank : 806)
Query Neighborhood Hits	1113	Target Neighborhood Hits	986	Shared Neighborhood Hits	110
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

EP400_HUMAN
NC score	0.012537 (rank : 1219)	θ value	3.0926 (rank : 948)
Query Neighborhood Hits	1113	Target Neighborhood Hits	556	Shared Neighborhood Hits	92
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

SMRC2_MOUSE
NC score	0.012017 (rank : 1220)	θ value	2.36792 (rank : 930)
Query Neighborhood Hits	1113	Target Neighborhood Hits	487	Shared Neighborhood Hits	64
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

CNOT3_HUMAN
NC score	0.011687 (rank : 1221)	θ value	8.99809 (rank : 1081)
Query Neighborhood Hits	1113	Target Neighborhood Hits	425	Shared Neighborhood Hits	61
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

RAGE_MOUSE
NC score	0.011678 (rank : 1222)	θ value	1.06291 (rank : 853)
Query Neighborhood Hits	1113	Target Neighborhood Hits	295	Shared Neighborhood Hits	15
SwissProt Accessions	Q62151	Gene names	Ager, Rage
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

GAK5_HUMAN
NC score	0.011520 (rank : 1223)	θ value	5.27518 (rank : 1027)
Query Neighborhood Hits	1113	Target Neighborhood Hits	429	Shared Neighborhood Hits	128
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

YETS2_MOUSE
NC score	0.011160 (rank : 1224)	θ value	8.99809 (rank : 1109)
Query Neighborhood Hits	1113	Target Neighborhood Hits	278	Shared Neighborhood Hits	63
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

ZCH14_HUMAN
NC score	0.010947 (rank : 1225)	θ value	5.27518 (rank : 1053)
Query Neighborhood Hits	1113	Target Neighborhood Hits	117	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WYQ9, O60324, Q9UFP0	Gene names	ZCCHC14, KIAA0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

SELV_HUMAN
NC score	0.010797 (rank : 1226)	θ value	6.88961 (rank : 1071)
Query Neighborhood Hits	1113	Target Neighborhood Hits	118	Shared Neighborhood Hits	34
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

SYMPK_MOUSE
NC score	0.010792 (rank : 1227)	θ value	0.365318 (rank : 769)
Query Neighborhood Hits	1113	Target Neighborhood Hits	109	Shared Neighborhood Hits	15
SwissProt Accessions	Q80X82	Gene names	Sympk
Domain Architecture	No domain graphic available
Description	Symplekin.

3BP1_MOUSE
NC score	0.010732 (rank : 1228)	θ value	1.06291 (rank : 832)
Query Neighborhood Hits	1113	Target Neighborhood Hits	238	Shared Neighborhood Hits	41
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

EWS_HUMAN
NC score	0.010644 (rank : 1229)	θ value	0.163984 (rank : 716)
Query Neighborhood Hits	1113	Target Neighborhood Hits	249	Shared Neighborhood Hits	32
SwissProt Accessions	Q01844, Q92635	Gene names	EWSR1, EWS
Domain Architecture
Description	RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein).

TAF1C_HUMAN
NC score	0.010517 (rank : 1230)	θ value	1.38821 (rank : 880)
Query Neighborhood Hits	1113	Target Neighborhood Hits	36	Shared Neighborhood Hits	11
SwissProt Accessions	Q15572, Q59F67, Q8N6V3	Gene names	TAF1C
Domain Architecture	No domain graphic available
Description	TATA box-binding protein-associated factor RNA polymerase I subunit C (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (TBP-associated factor RNA polymerase I 110 kDa) (TAFI110).

NCOA3_HUMAN
NC score	0.010482 (rank : 1231)	θ value	0.365318 (rank : 763)
Query Neighborhood Hits	1113	Target Neighborhood Hits	171	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

CENPU_HUMAN
NC score	0.010153 (rank : 1232)	θ value	8.99809 (rank : 1080)
Query Neighborhood Hits	1113	Target Neighborhood Hits	289	Shared Neighborhood Hits	20
SwissProt Accessions	Q71F23, Q32Q71, Q9H5G1	Gene names	MLF1IP, CENPU, ICEN24, KLIP1
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (CENP-U(50)) (CENP-50) (Interphase centromere complex protein 24) (MLF1-interacting protein) (KSHV latent nuclear antigen-interacting protein 1).

CHCH2_MOUSE
NC score	0.009694 (rank : 1233)	θ value	6.88961 (rank : 1061)
Query Neighborhood Hits	1113	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D1L0, Q3TUG8	Gene names	Chchd2
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 2.

SRBP1_HUMAN
NC score	0.009407 (rank : 1234)	θ value	2.36792 (rank : 933)
Query Neighborhood Hits	1113	Target Neighborhood Hits	225	Shared Neighborhood Hits	44
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

NCOA2_HUMAN
NC score	0.009323 (rank : 1235)	θ value	1.81305 (rank : 900)
Query Neighborhood Hits	1113	Target Neighborhood Hits	281	Shared Neighborhood Hits	49
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

AKAP2_HUMAN
NC score	0.009303 (rank : 1236)	θ value	4.03905 (rank : 979)
Query Neighborhood Hits	1113	Target Neighborhood Hits	507	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

ZN598_HUMAN
NC score	0.008680 (rank : 1237)	θ value	3.0926 (rank : 976)
Query Neighborhood Hits	1113	Target Neighborhood Hits	339	Shared Neighborhood Hits	44
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

TTC15_MOUSE
NC score	0.008432 (rank : 1238)	θ value	2.36792 (rank : 938)
Query Neighborhood Hits	1113	Target Neighborhood Hits	113	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K2L8, Q8BX27	Gene names	Ttc15
Domain Architecture
Description	Tetratricopeptide repeat protein 15 (TPR repeat protein 15).

LSD1_MOUSE
NC score	0.006899 (rank : 1239)	θ value	8.99809 (rank : 1093)
Query Neighborhood Hits	1113	Target Neighborhood Hits	224	Shared Neighborhood Hits	27
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

RC3H1_MOUSE
NC score	0.006715 (rank : 1240)	θ value	1.38821 (rank : 876)
Query Neighborhood Hits	1113	Target Neighborhood Hits	244	Shared Neighborhood Hits	17
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

POLS_MOUSE
NC score	0.006566 (rank : 1241)	θ value	6.88961 (rank : 1067)
Query Neighborhood Hits	1113	Target Neighborhood Hits	91	Shared Neighborhood Hits	37
SwissProt Accessions	Q6PB75	Gene names	Pols
Domain Architecture	No domain graphic available
Description	DNA polymerase sigma (EC 2.7.7.7).

XRN1_MOUSE
NC score	0.006338 (rank : 1242)	θ value	5.27518 (rank : 1051)
Query Neighborhood Hits	1113	Target Neighborhood Hits	64	Shared Neighborhood Hits	12
SwissProt Accessions	P97789, O35651, P97790, Q3TE44, Q3TRE9, Q3UQL5	Gene names	Xrn1, Dhm2, Exo, Sep1
Domain Architecture	No domain graphic available
Description	5'-3' exoribonuclease 1 (EC 3.1.11.-) (mXRN1) (Strand-exchange protein 1 homolog) (Protein Dhm2).

YAP1_HUMAN
NC score	0.006326 (rank : 1243)	θ value	3.0926 (rank : 974)
Query Neighborhood Hits	1113	Target Neighborhood Hits	173	Shared Neighborhood Hits	38
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

ITSN1_MOUSE
NC score	0.006250 (rank : 1244)	θ value	0.47712 (rank : 783)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1669	Shared Neighborhood Hits	127
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

IRAK1_HUMAN
NC score	0.006133 (rank : 1245)	θ value	4.03905 (rank : 994)
Query Neighborhood Hits	1113	Target Neighborhood Hits	820	Shared Neighborhood Hits	52
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

TM16H_HUMAN
NC score	0.005912 (rank : 1246)	θ value	2.36792 (rank : 936)
Query Neighborhood Hits	1113	Target Neighborhood Hits	139	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HCE9	Gene names	TMEM16H, KIAA1623
Domain Architecture	No domain graphic available
Description	Transmembrane protein 16H.

FGD1_HUMAN
NC score	0.005185 (rank : 1247)	θ value	5.27518 (rank : 1023)
Query Neighborhood Hits	1113	Target Neighborhood Hits	367	Shared Neighborhood Hits	55
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FILA_HUMAN
NC score	0.004899 (rank : 1248)	θ value	2.36792 (rank : 918)
Query Neighborhood Hits	1113	Target Neighborhood Hits	685	Shared Neighborhood Hits	54
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

WNK2_HUMAN
NC score	0.004622 (rank : 1249)	θ value	0.279714 (rank : 749)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1407	Shared Neighborhood Hits	162
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

OBSCN_HUMAN
NC score	0.004533 (rank : 1250)	θ value	2.36792 (rank : 925)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1931	Shared Neighborhood Hits	186
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

FBX46_MOUSE
NC score	0.004530 (rank : 1251)	θ value	8.99809 (rank : 1089)
Query Neighborhood Hits	1113	Target Neighborhood Hits	139	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BG80	Gene names	Fbxo46, Fbx46, Fbxo34l
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

ITSN1_HUMAN
NC score	0.004387 (rank : 1252)	θ value	0.813845 (rank : 820)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1757	Shared Neighborhood Hits	148
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

HCN2_HUMAN
NC score	0.004343 (rank : 1253)	θ value	1.06291 (rank : 840)
Query Neighborhood Hits	1113	Target Neighborhood Hits	369	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

TRAF6_MOUSE
NC score	0.004238 (rank : 1254)	θ value	0.813845 (rank : 829)
Query Neighborhood Hits	1113	Target Neighborhood Hits	255	Shared Neighborhood Hits	17
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

TBX4_HUMAN
NC score	0.004203 (rank : 1255)	θ value	0.813845 (rank : 826)
Query Neighborhood Hits	1113	Target Neighborhood Hits	70	Shared Neighborhood Hits	15
SwissProt Accessions	P57082	Gene names	TBX4
Domain Architecture
Description	T-box transcription factor TBX4 (T-box protein 4).

MYST3_MOUSE
NC score	0.004135 (rank : 1256)	θ value	8.99809 (rank : 1097)
Query Neighborhood Hits	1113	Target Neighborhood Hits	688	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

EWS_MOUSE
NC score	0.003957 (rank : 1257)	θ value	3.0926 (rank : 950)
Query Neighborhood Hits	1113	Target Neighborhood Hits	271	Shared Neighborhood Hits	30
SwissProt Accessions	Q61545	Gene names	Ewsr1, Ews, Ewsh
Domain Architecture
Description	RNA-binding protein EWS.

HDAC7_MOUSE
NC score	0.003786 (rank : 1258)	θ value	1.06291 (rank : 841)
Query Neighborhood Hits	1113	Target Neighborhood Hits	85	Shared Neighborhood Hits	20
SwissProt Accessions	Q8C2B3, Q8C2C9, Q8C8X4, Q8CB80, Q8CDA3, Q9JL72	Gene names	Hdac7a, Hdac7
Domain Architecture
Description	Histone deacetylase 7a (HD7a).

AAK1_MOUSE
NC score	0.003736 (rank : 1259)	θ value	0.0736092 (rank : 669)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1051	Shared Neighborhood Hits	128
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

MYST3_HUMAN
NC score	0.003635 (rank : 1260)	θ value	5.27518 (rank : 1041)
Query Neighborhood Hits	1113	Target Neighborhood Hits	772	Shared Neighborhood Hits	79
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

RFTN1_HUMAN
NC score	0.003553 (rank : 1261)	θ value	6.88961 (rank : 1069)
Query Neighborhood Hits	1113	Target Neighborhood Hits	72	Shared Neighborhood Hits	10
SwissProt Accessions	Q14699, Q496Y2, Q4QQI7, Q5JB48, Q7Z7P2	Gene names	RFTN1, KIAA0084
Domain Architecture	No domain graphic available
Description	Raftlin (Raft-linking protein) (Cell migration-inducing gene 2 protein).

JHD2C_MOUSE
NC score	0.003349 (rank : 1262)	θ value	5.27518 (rank : 1032)
Query Neighborhood Hits	1113	Target Neighborhood Hits	297	Shared Neighborhood Hits	27
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

HCN4_HUMAN
NC score	0.003261 (rank : 1263)	θ value	5.27518 (rank : 1029)
Query Neighborhood Hits	1113	Target Neighborhood Hits	303	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HXA3_MOUSE
NC score	0.003217 (rank : 1264)	θ value	0.00869519 (rank : 584)
Query Neighborhood Hits	1113	Target Neighborhood Hits	558	Shared Neighborhood Hits	63
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

AAK1_HUMAN
NC score	0.003016 (rank : 1265)	θ value	0.47712 (rank : 770)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1077	Shared Neighborhood Hits	128
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

YAP1_MOUSE
NC score	0.002985 (rank : 1266)	θ value	2.36792 (rank : 940)
Query Neighborhood Hits	1113	Target Neighborhood Hits	96	Shared Neighborhood Hits	13
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

MGR1_MOUSE
NC score	0.002902 (rank : 1267)	θ value	5.27518 (rank : 1038)
Query Neighborhood Hits	1113	Target Neighborhood Hits	90	Shared Neighborhood Hits	12
SwissProt Accessions	P97772, Q6AXG4, Q9EPV6	Gene names	Grm1, Gprc1a, Mglur1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

SMCA4_HUMAN
NC score	0.002872 (rank : 1268)	θ value	3.0926 (rank : 967)
Query Neighborhood Hits	1113	Target Neighborhood Hits	597	Shared Neighborhood Hits	79
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

LYL1_HUMAN
NC score	0.002509 (rank : 1269)	θ value	3.0926 (rank : 958)
Query Neighborhood Hits	1113	Target Neighborhood Hits	113	Shared Neighborhood Hits	11
SwissProt Accessions	P12980, O76102	Gene names	LYL1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

SOS1_HUMAN
NC score	0.002455 (rank : 1270)	θ value	8.99809 (rank : 1105)
Query Neighborhood Hits	1113	Target Neighborhood Hits	274	Shared Neighborhood Hits	49
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

CD45_MOUSE
NC score	0.002435 (rank : 1271)	θ value	0.62314 (rank : 792)
Query Neighborhood Hits	1113	Target Neighborhood Hits	178	Shared Neighborhood Hits	28
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

AP3B2_HUMAN
NC score	0.002251 (rank : 1272)	θ value	5.27518 (rank : 1017)
Query Neighborhood Hits	1113	Target Neighborhood Hits	246	Shared Neighborhood Hits	25
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

ATF5_MOUSE
NC score	0.002142 (rank : 1273)	θ value	6.88961 (rank : 1056)
Query Neighborhood Hits	1113	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	O70191, Q58E51, Q99NH6	Gene names	Atf5, Atfx, Nap1
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-5 (Activating transcription factor 5-alpha/beta) (Transcription factor ATFx) (Transcription factor-like protein ODA-10) (BZIP protein ATF7) (NRIF3- associated protein) (NAP1).

HDAC7_HUMAN
NC score	0.002091 (rank : 1274)	θ value	4.03905 (rank : 992)
Query Neighborhood Hits	1113	Target Neighborhood Hits	64	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WUI4, Q7Z5I1, Q96K01, Q9BR73, Q9H7L0, Q9NW41, Q9NWA9, Q9NYK9, Q9UFU7	Gene names	HDAC7A, HDAC7
Domain Architecture
Description	Histone deacetylase 7a (HD7a).

MAST4_HUMAN
NC score	0.002082 (rank : 1275)	θ value	1.81305 (rank : 894)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1804	Shared Neighborhood Hits	199
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

ABL1_HUMAN
NC score	0.001963 (rank : 1276)	θ value	6.88961 (rank : 1055)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1220	Shared Neighborhood Hits	91
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

BT3A1_HUMAN
NC score	0.001483 (rank : 1277)	θ value	5.27518 (rank : 1019)
Query Neighborhood Hits	1113	Target Neighborhood Hits	229	Shared Neighborhood Hits	19
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

ANX11_HUMAN
NC score	0.001469 (rank : 1278)	θ value	1.06291 (rank : 834)
Query Neighborhood Hits	1113	Target Neighborhood Hits	192	Shared Neighborhood Hits	36
SwissProt Accessions	P50995	Gene names	ANXA11, ANX11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50) (56 kDa autoantigen).

ZC3H8_HUMAN
NC score	0.001282 (rank : 1279)	θ value	5.27518 (rank : 1052)
Query Neighborhood Hits	1113	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N5P1, Q9BZ75	Gene names	ZC3H8, ZC3HDC8
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 8.

SI1L1_HUMAN
NC score	0.001191 (rank : 1280)	θ value	4.03905 (rank : 1003)
Query Neighborhood Hits	1113	Target Neighborhood Hits	162	Shared Neighborhood Hits	8
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

AP3B2_MOUSE
NC score	0.001125 (rank : 1281)	θ value	5.27518 (rank : 1018)
Query Neighborhood Hits	1113	Target Neighborhood Hits	246	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

CRK_MOUSE
NC score	0.000794 (rank : 1282)	θ value	0.813845 (rank : 815)
Query Neighborhood Hits	1113	Target Neighborhood Hits	314	Shared Neighborhood Hits	22
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

LDB3_HUMAN
NC score	0.000612 (rank : 1283)	θ value	1.06291 (rank : 845)
Query Neighborhood Hits	1113	Target Neighborhood Hits	497	Shared Neighborhood Hits	58
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

LRC50_HUMAN
NC score	0.000598 (rank : 1284)	θ value	5.27518 (rank : 1036)
Query Neighborhood Hits	1113	Target Neighborhood Hits	275	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NEP3, Q69YI8, Q69YJ0, Q96LP3	Gene names	LRRC50
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 50.

WNK4_HUMAN
NC score	0.000515 (rank : 1285)	θ value	1.81305 (rank : 908)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1043	Shared Neighborhood Hits	91
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

CRK_HUMAN
NC score	0.000476 (rank : 1286)	θ value	1.06291 (rank : 839)
Query Neighborhood Hits	1113	Target Neighborhood Hits	308	Shared Neighborhood Hits	19
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

WNK1_HUMAN
NC score	0.000188 (rank : 1287)	θ value	6.88961 (rank : 1077)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1158	Shared Neighborhood Hits	123
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

RN123_MOUSE
NC score	0.000133 (rank : 1288)	θ value	8.99809 (rank : 1103)
Query Neighborhood Hits	1113	Target Neighborhood Hits	174	Shared Neighborhood Hits	11
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RXRB_HUMAN
NC score	0.000100 (rank : 1289)	θ value	0.47712 (rank : 786)
Query Neighborhood Hits	1113	Target Neighborhood Hits	280	Shared Neighborhood Hits	52
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

LDB3_MOUSE
NC score	-0.000027 (rank : 1290)	θ value	5.27518 (rank : 1035)
Query Neighborhood Hits	1113	Target Neighborhood Hits	510	Shared Neighborhood Hits	72
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

DYN2_MOUSE
NC score	-0.000106 (rank : 1291)	θ value	8.99809 (rank : 1088)
Query Neighborhood Hits	1113	Target Neighborhood Hits	104	Shared Neighborhood Hits	17
SwissProt Accessions	P39054, Q9DBE1	Gene names	Dnm2, Dyn2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM).

IGHG3_HUMAN
NC score	-0.000158 (rank : 1292)	θ value	4.03905 (rank : 993)
Query Neighborhood Hits	1113	Target Neighborhood Hits	234	Shared Neighborhood Hits	9
SwissProt Accessions	P01860	Gene names	IGHG3
Domain Architecture
Description	Ig gamma-3 chain C region (Heavy chain disease protein) (HDC).

DMN_HUMAN
NC score	-0.000531 (rank : 1293)	θ value	8.99809 (rank : 1085)
Query Neighborhood Hits	1113	Target Neighborhood Hits	690	Shared Neighborhood Hits	54
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

GMIP_HUMAN
NC score	-0.000602 (rank : 1294)	θ value	3.0926 (rank : 953)
Query Neighborhood Hits	1113	Target Neighborhood Hits	225	Shared Neighborhood Hits	20
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

SIM1_HUMAN
NC score	-0.000608 (rank : 1295)	θ value	4.03905 (rank : 1004)
Query Neighborhood Hits	1113	Target Neighborhood Hits	62	Shared Neighborhood Hits	9
SwissProt Accessions	P81133, Q5TDP7	Gene names	SIM1
Domain Architecture
Description	Single-minded homolog 1.

HXA3_HUMAN
NC score	-0.001001 (rank : 1296)	θ value	0.47712 (rank : 782)
Query Neighborhood Hits	1113	Target Neighborhood Hits	535	Shared Neighborhood Hits	53
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

KRHB5_MOUSE
NC score	-0.001741 (rank : 1297)	θ value	5.27518 (rank : 1034)
Query Neighborhood Hits	1113	Target Neighborhood Hits	294	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z2T6, Q8CE83, Q9D7M4	Gene names	Krthb5, Krt2-18
Domain Architecture
Description	Keratin, type II cuticular Hb5 (Hair keratin, type II Hb5).

UBP38_HUMAN
NC score	-0.001817 (rank : 1298)	θ value	5.27518 (rank : 1050)
Query Neighborhood Hits	1113	Target Neighborhood Hits	97	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

CD2L7_HUMAN
NC score	-0.002300 (rank : 1299)	θ value	1.06291 (rank : 836)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1275	Shared Neighborhood Hits	121
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

SN1L2_HUMAN
NC score	-0.002375 (rank : 1300)	θ value	0.125558 (rank : 701)
Query Neighborhood Hits	1113	Target Neighborhood Hits	964	Shared Neighborhood Hits	73
SwissProt Accessions	Q9H0K1, O94878, Q6AZE2, Q76N03, Q8NCV7, Q96CZ8	Gene names	SNF1LK2, KIAA0781, QIK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Qin- induced kinase).

FX4L4_HUMAN
NC score	-0.002377 (rank : 1301)	θ value	0.365318 (rank : 759)
Query Neighborhood Hits	1113	Target Neighborhood Hits	101	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WXT5	Gene names	FOXD4L4, FOXD4B
Domain Architecture
Description	Forkhead box protein D4-like 4 (Forkhead box protein D4B) (Myeloid factor-gamma).

MK07_HUMAN
NC score	-0.002996 (rank : 1302)	θ value	0.0736092 (rank : 674)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1087	Shared Neighborhood Hits	104
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

FOXL2_HUMAN
NC score	-0.003753 (rank : 1303)	θ value	5.27518 (rank : 1025)
Query Neighborhood Hits	1113	Target Neighborhood Hits	142	Shared Neighborhood Hits	17
SwissProt Accessions	P58012, Q4ZGJ3	Gene names	FOXL2
Domain Architecture
Description	Forkhead box protein L2.

SRPK1_HUMAN
NC score	-0.003978 (rank : 1304)	θ value	0.21417 (rank : 734)
Query Neighborhood Hits	1113	Target Neighborhood Hits	706	Shared Neighborhood Hits	41
SwissProt Accessions	Q96SB4, Q12890, Q5R364, Q5R365, Q8IY12	Gene names	SRPK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

TLX3_HUMAN
NC score	-0.004410 (rank : 1305)	θ value	0.21417 (rank : 736)
Query Neighborhood Hits	1113	Target Neighborhood Hits	403	Shared Neighborhood Hits	19
SwissProt Accessions	O43711, Q96AD3	Gene names	TLX3, HOX11L2
Domain Architecture
Description	T-cell leukemia homeobox protein 3 (Homeobox protein Hox-11L2).

DMWD_MOUSE
NC score	-0.004464 (rank : 1306)	θ value	8.99809 (rank : 1087)
Query Neighborhood Hits	1113	Target Neighborhood Hits	282	Shared Neighborhood Hits	18
SwissProt Accessions	Q08274	Gene names	Dmwd, Dm9
Domain Architecture
Description	Dystrophia myotonica WD repeat-containing protein (Dystrophia myotonica-containing WD repeat motif protein) (DMR-N9 protein).

TLX3_MOUSE
NC score	-0.004465 (rank : 1307)	θ value	0.0736092 (rank : 679)
Query Neighborhood Hits	1113	Target Neighborhood Hits	346	Shared Neighborhood Hits	10
SwissProt Accessions	O55144	Gene names	Tlx3, Hox11l2, Rnx, Tlx1l2
Domain Architecture
Description	T-cell leukemia homeobox protein 3 (Homeobox TLX-3) (Homeobox protein Hox-11L2) (Respiratory neuron homeobox protein).

MK07_MOUSE
NC score	-0.004653 (rank : 1308)	θ value	1.81305 (rank : 896)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1054	Shared Neighborhood Hits	96
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

ESX1L_HUMAN
NC score	-0.004740 (rank : 1309)	θ value	1.38821 (rank : 867)
Query Neighborhood Hits	1113	Target Neighborhood Hits	498	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N693, Q7Z6K7	Gene names	ESX1L, ESX1R
Domain Architecture
Description	Extraembryonic, spermatogenesis, homeobox 1-like protein.

PAK6_HUMAN
NC score	-0.004885 (rank : 1310)	θ value	0.813845 (rank : 821)
Query Neighborhood Hits	1113	Target Neighborhood Hits	915	Shared Neighborhood Hits	68
SwissProt Accessions	Q9NQU5	Gene names	PAK6, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (p21-activated kinase 6) (PAK-6) (PAK-5).

BRSK2_HUMAN
NC score	-0.005097 (rank : 1311)	θ value	3.0926 (rank : 944)
Query Neighborhood Hits	1113	Target Neighborhood Hits	897	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IWQ3, O60843, O95099, Q5J5B4, Q8TB60	Gene names	BRSK2, C11orf7, PEN11B, STK29
Domain Architecture
Description	BR serine/threonine-protein kinase 2 (EC 2.7.11.1) (Serine/threonine- protein kinase 29) (SAD1B).

DDX4_HUMAN
NC score	-0.006582 (rank : 1312)	θ value	8.99809 (rank : 1083)
Query Neighborhood Hits	1113	Target Neighborhood Hits	123	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

MAST2_MOUSE
NC score	-0.006753 (rank : 1313)	θ value	6.88961 (rank : 1065)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1110	Shared Neighborhood Hits	75
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MSX1_HUMAN
NC score	-0.008324 (rank : 1314)	θ value	1.81305 (rank : 898)
Query Neighborhood Hits	1113	Target Neighborhood Hits	374	Shared Neighborhood Hits	18
SwissProt Accessions	P28360, Q96NY4	Gene names	MSX1, HOX7
Domain Architecture
Description	Homeobox protein MSX-1 (Msh homeobox 1-like protein) (Hox-7).

TTBK2_HUMAN
NC score	-0.009229 (rank : 1315)	θ value	1.81305 (rank : 906)
Query Neighborhood Hits	1113	Target Neighborhood Hits	822	Shared Neighborhood Hits	52
SwissProt Accessions	Q6IQ55, O94932, Q6ZN52, Q8IVV1	Gene names	TTBK2, KIAA0847
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2 (EC 2.7.11.1).

ALX3_MOUSE
NC score	-0.009339 (rank : 1316)	θ value	5.27518 (rank : 1014)
Query Neighborhood Hits	1113	Target Neighborhood Hits	386	Shared Neighborhood Hits	15
SwissProt Accessions	O70137	Gene names	Alx3
Domain Architecture
Description	Homeobox protein aristaless-like 3 (Proline-rich transcription factor ALX3).

ZEP1_HUMAN
NC score	-0.009842 (rank : 1317)	θ value	8.99809 (rank : 1112)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1036	Shared Neighborhood Hits	88
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

ZEP1_MOUSE
NC score	-0.012012 (rank : 1318)	θ value	8.99809 (rank : 1113)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1063	Shared Neighborhood Hits	81
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

PRDM2_HUMAN
NC score	-0.012497 (rank : 1319)	θ value	1.06291 (rank : 851)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1135	Shared Neighborhood Hits	97
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

ZN592_MOUSE
NC score	-0.012732 (rank : 1320)	θ value	0.0148317 (rank : 615)
Query Neighborhood Hits	1113	Target Neighborhood Hits	768	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BHZ4, Q80XM1	Gene names	Znf592, Kiaa0211, Zfp592
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592 (Zfp-592).

ZEP2_MOUSE
NC score	-0.014661 (rank : 1321)	θ value	3.0926 (rank : 975)
Query Neighborhood Hits	1113	Target Neighborhood Hits	964	Shared Neighborhood Hits	67
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

SALL3_HUMAN
NC score	-0.014679 (rank : 1322)	θ value	1.38821 (rank : 877)
Query Neighborhood Hits	1113	Target Neighborhood Hits	1066	Shared Neighborhood Hits	80
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

ZBTB3_HUMAN
NC score	-0.016566 (rank : 1323)	θ value	1.81305 (rank : 909)
Query Neighborhood Hits	1113	Target Neighborhood Hits	910	Shared Neighborhood Hits	59
SwissProt Accessions	Q9H5J0	Gene names	ZBTB3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

GLIS1_HUMAN
NC score	-0.018924 (rank : 1324)	θ value	2.36792 (rank : 920)
Query Neighborhood Hits	1113	Target Neighborhood Hits	748	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NBF1, Q8N9V9	Gene names	GLIS1
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS1 (GLI-similar 1).

KLF4_HUMAN
NC score	-0.019143 (rank : 1325)	θ value	3.0926 (rank : 956)
Query Neighborhood Hits	1113	Target Neighborhood Hits	709	Shared Neighborhood Hits	25
SwissProt Accessions	O43474, P78338, Q9UNP3	Gene names	KLF4, EZF, GKLF
Domain Architecture
Description	Krueppel-like factor 4 (Epithelial zinc-finger protein EZF) (Gut- enriched krueppel-like factor).

ZBT45_HUMAN
NC score	-0.019199 (rank : 1326)	θ value	1.06291 (rank : 857)
Query Neighborhood Hits	1113	Target Neighborhood Hits	901	Shared Neighborhood Hits	47
SwissProt Accessions	Q96K62	Gene names	ZBTB45, ZNF499
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 45 (Zinc finger protein 499).

ZSCA2_MOUSE
NC score	-0.019840 (rank : 1327)	θ value	2.36792 (rank : 942)
Query Neighborhood Hits	1113	Target Neighborhood Hits	767	Shared Neighborhood Hits	24
SwissProt Accessions	Q07230	Gene names	Zscan2, Zfp-29, Zfp29
Domain Architecture
Description	Zinc finger and SCAN domain-containing protein 2 (Zinc finger protein 29) (Zfp-29).

EGR1_HUMAN
NC score	-0.020236 (rank : 1328)	θ value	5.27518 (rank : 1022)
Query Neighborhood Hits	1113	Target Neighborhood Hits	788	Shared Neighborhood Hits	29
SwissProt Accessions	P18146	Gene names	EGR1, ZNF225
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Zinc finger protein 225) (AT225).