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Network neighborhood for query Sequence : NCOA3_HUMAN

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NCOA3_HUMAN
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NCOA2_HUMAN
θ value	0 (rank : 1)	NC score	0.934324 (rank : 3)
Query Neighborhood Hits	171	Target Neighborhood Hits	281	Shared Neighborhood Hits	56
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

NCOA2_MOUSE
θ value	0 (rank : 2)	NC score	0.932488 (rank : 4)
Query Neighborhood Hits	171	Target Neighborhood Hits	281	Shared Neighborhood Hits	53
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

NCOA3_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	171	Target Neighborhood Hits	171	Shared Neighborhood Hits	171
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

NCOA3_MOUSE
θ value	0 (rank : 4)	NC score	0.966968 (rank : 2)
Query Neighborhood Hits	171	Target Neighborhood Hits	203	Shared Neighborhood Hits	63
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

NCOA1_HUMAN
θ value	3.5201e-129 (rank : 5)	NC score	0.910960 (rank : 6)
Query Neighborhood Hits	171	Target Neighborhood Hits	198	Shared Neighborhood Hits	43
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

NCOA1_MOUSE
θ value	2.36115e-125 (rank : 6)	NC score	0.912004 (rank : 5)
Query Neighborhood Hits	171	Target Neighborhood Hits	196	Shared Neighborhood Hits	47
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

BMAL1_MOUSE
θ value	5.07402e-19 (rank : 7)	NC score	0.603881 (rank : 9)
Query Neighborhood Hits	171	Target Neighborhood Hits	121	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

BMAL1_HUMAN
θ value	2.5182e-18 (rank : 8)	NC score	0.604957 (rank : 8)
Query Neighborhood Hits	171	Target Neighborhood Hits	115	Shared Neighborhood Hits	38
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

ARNT2_MOUSE
θ value	4.44505e-15 (rank : 9)	NC score	0.575044 (rank : 13)
Query Neighborhood Hits	171	Target Neighborhood Hits	115	Shared Neighborhood Hits	36
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_HUMAN
θ value	5.8054e-15 (rank : 10)	NC score	0.574792 (rank : 14)
Query Neighborhood Hits	171	Target Neighborhood Hits	109	Shared Neighborhood Hits	35
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

CLOCK_MOUSE
θ value	9.90251e-15 (rank : 11)	NC score	0.605117 (rank : 7)
Query Neighborhood Hits	171	Target Neighborhood Hits	148	Shared Neighborhood Hits	44
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

CLOCK_HUMAN
θ value	1.68911e-14 (rank : 12)	NC score	0.602801 (rank : 10)
Query Neighborhood Hits	171	Target Neighborhood Hits	127	Shared Neighborhood Hits	42
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

ARNT_HUMAN
θ value	6.41864e-14 (rank : 13)	NC score	0.563631 (rank : 21)
Query Neighborhood Hits	171	Target Neighborhood Hits	109	Shared Neighborhood Hits	37
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ARNT_MOUSE
θ value	4.16044e-13 (rank : 14)	NC score	0.555782 (rank : 25)
Query Neighborhood Hits	171	Target Neighborhood Hits	213	Shared Neighborhood Hits	45
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

AHR_MOUSE
θ value	2.0648e-12 (rank : 15)	NC score	0.582022 (rank : 12)
Query Neighborhood Hits	171	Target Neighborhood Hits	55	Shared Neighborhood Hits	36
SwissProt Accessions	P30561, Q8QZX6, Q8R4S3, Q99P79, Q9QVY1	Gene names	Ahr
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

AHR_HUMAN
θ value	3.52202e-12 (rank : 16)	NC score	0.589777 (rank : 11)
Query Neighborhood Hits	171	Target Neighborhood Hits	47	Shared Neighborhood Hits	34
SwissProt Accessions	P35869, Q13728, Q13803, Q13804	Gene names	AHR
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

EPAS1_MOUSE
θ value	7.84624e-12 (rank : 17)	NC score	0.569862 (rank : 16)
Query Neighborhood Hits	171	Target Neighborhood Hits	94	Shared Neighborhood Hits	38
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

EPAS1_HUMAN
θ value	2.28291e-11 (rank : 18)	NC score	0.566111 (rank : 19)
Query Neighborhood Hits	171	Target Neighborhood Hits	76	Shared Neighborhood Hits	35
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

HIF1A_MOUSE
θ value	6.64225e-11 (rank : 19)	NC score	0.566854 (rank : 18)
Query Neighborhood Hits	171	Target Neighborhood Hits	90	Shared Neighborhood Hits	39
SwissProt Accessions	Q61221, O08741, O08993, Q61664, Q61665, Q8C681, Q8CC19, Q8CCB6, Q8R385, Q9CYA8	Gene names	Hif1a
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein).

HIF1A_HUMAN
θ value	1.47974e-10 (rank : 20)	NC score	0.565466 (rank : 20)
Query Neighborhood Hits	171	Target Neighborhood Hits	118	Shared Neighborhood Hits	37
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

SIM2_MOUSE
θ value	3.29651e-10 (rank : 21)	NC score	0.555783 (rank : 24)
Query Neighborhood Hits	171	Target Neighborhood Hits	75	Shared Neighborhood Hits	34
SwissProt Accessions	Q61079, O35391, Q61046, Q61904	Gene names	Sim2
Domain Architecture
Description	Single-minded homolog 2 (SIM transcription factor) (mSIM).

SIM1_HUMAN
θ value	4.30538e-10 (rank : 22)	NC score	0.562303 (rank : 22)
Query Neighborhood Hits	171	Target Neighborhood Hits	62	Shared Neighborhood Hits	36
SwissProt Accessions	P81133, Q5TDP7	Gene names	SIM1
Domain Architecture
Description	Single-minded homolog 1.

SIM1_MOUSE
θ value	4.30538e-10 (rank : 23)	NC score	0.561427 (rank : 23)
Query Neighborhood Hits	171	Target Neighborhood Hits	69	Shared Neighborhood Hits	36
SwissProt Accessions	Q61045, O70284, P70183	Gene names	Sim1
Domain Architecture
Description	Single-minded homolog 1 (mSIM1).

NPAS2_MOUSE
θ value	2.13673e-09 (rank : 24)	NC score	0.572833 (rank : 15)
Query Neighborhood Hits	171	Target Neighborhood Hits	132	Shared Neighborhood Hits	45
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

NPAS2_HUMAN
θ value	3.64472e-09 (rank : 25)	NC score	0.569420 (rank : 17)
Query Neighborhood Hits	171	Target Neighborhood Hits	150	Shared Neighborhood Hits	42
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

SIM2_HUMAN
θ value	1.38499e-08 (rank : 26)	NC score	0.553234 (rank : 26)
Query Neighborhood Hits	171	Target Neighborhood Hits	76	Shared Neighborhood Hits	35
SwissProt Accessions	Q14190, O60766, Q15470, Q15471, Q15472, Q15473, Q16532	Gene names	SIM2
Domain Architecture
Description	Single-minded homolog 2.

NPAS1_MOUSE
θ value	6.87365e-08 (rank : 27)	NC score	0.537310 (rank : 27)
Query Neighborhood Hits	171	Target Neighborhood Hits	63	Shared Neighborhood Hits	35
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).

NPAS1_HUMAN
θ value	2.61198e-07 (rank : 28)	NC score	0.527169 (rank : 28)
Query Neighborhood Hits	171	Target Neighborhood Hits	77	Shared Neighborhood Hits	34
SwissProt Accessions	Q99742, Q99632, Q9BY83	Gene names	NPAS1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1) (Member of PAS protein 5) (MOP5).

NPAS3_HUMAN
θ value	7.59969e-07 (rank : 29)	NC score	0.521640 (rank : 30)
Query Neighborhood Hits	171	Target Neighborhood Hits	81	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IXF0, Q86US6, Q86US7, Q8IXF2, Q9BY81, Q9H323, Q9Y4L8	Gene names	NPAS3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

NPAS3_MOUSE
θ value	7.59969e-07 (rank : 30)	NC score	0.524212 (rank : 29)
Query Neighborhood Hits	171	Target Neighborhood Hits	103	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QZQ0, Q9EQP4	Gene names	Npas3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

HGS_HUMAN
θ value	0.00390308 (rank : 31)	NC score	0.074741 (rank : 43)
Query Neighborhood Hits	171	Target Neighborhood Hits	517	Shared Neighborhood Hits	33
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

MLL3_HUMAN
θ value	0.00869519 (rank : 32)	NC score	0.051073 (rank : 78)
Query Neighborhood Hits	171	Target Neighborhood Hits	1644	Shared Neighborhood Hits	73
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

HGS_MOUSE
θ value	0.0148317 (rank : 33)	NC score	0.055896 (rank : 64)
Query Neighborhood Hits	171	Target Neighborhood Hits	589	Shared Neighborhood Hits	29
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

SSBP3_HUMAN
θ value	0.0193708 (rank : 34)	NC score	0.057454 (rank : 58)
Query Neighborhood Hits	171	Target Neighborhood Hits	132	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BWW4, Q9BTM0, Q9BWW3	Gene names	SSBP3, SSDP, SSDP1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein).

SSBP3_MOUSE
θ value	0.0193708 (rank : 35)	NC score	0.057454 (rank : 59)
Query Neighborhood Hits	171	Target Neighborhood Hits	132	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D032, Q99LC6, Q9EQP3	Gene names	Ssbp3, Last, Ssdp1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein) (Lck-associated signal transducer).

TEX15_HUMAN
θ value	0.0193708 (rank : 36)	NC score	0.059380 (rank : 56)
Query Neighborhood Hits	171	Target Neighborhood Hits	174	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BXT5	Gene names	TEX15
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 15 protein.

NFAT5_MOUSE
θ value	0.0252991 (rank : 37)	NC score	0.055581 (rank : 66)
Query Neighborhood Hits	171	Target Neighborhood Hits	162	Shared Neighborhood Hits	17
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

NPAS4_HUMAN
θ value	0.0252991 (rank : 38)	NC score	0.364593 (rank : 31)
Query Neighborhood Hits	171	Target Neighborhood Hits	214	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

NPAS4_MOUSE
θ value	0.0252991 (rank : 39)	NC score	0.357377 (rank : 32)
Query Neighborhood Hits	171	Target Neighborhood Hits	245	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

ROCK2_MOUSE
θ value	0.0252991 (rank : 40)	NC score	0.007541 (rank : 161)
Query Neighborhood Hits	171	Target Neighborhood Hits	2072	Shared Neighborhood Hits	28
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

ARI1A_HUMAN
θ value	0.0330416 (rank : 41)	NC score	0.084330 (rank : 41)
Query Neighborhood Hits	171	Target Neighborhood Hits	787	Shared Neighborhood Hits	58
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

EP300_HUMAN
θ value	0.0431538 (rank : 42)	NC score	0.064119 (rank : 52)
Query Neighborhood Hits	171	Target Neighborhood Hits	821	Shared Neighborhood Hits	63
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

NCOA6_MOUSE
θ value	0.0736092 (rank : 43)	NC score	0.115727 (rank : 40)
Query Neighborhood Hits	171	Target Neighborhood Hits	1076	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

TCF7_MOUSE
θ value	0.0736092 (rank : 44)	NC score	0.032768 (rank : 99)
Query Neighborhood Hits	171	Target Neighborhood Hits	277	Shared Neighborhood Hits	18
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

MRCKG_HUMAN
θ value	0.0961366 (rank : 45)	NC score	0.007137 (rank : 163)
Query Neighborhood Hits	171	Target Neighborhood Hits	1519	Shared Neighborhood Hits	22
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

NOTC2_MOUSE
θ value	0.0961366 (rank : 46)	NC score	0.009446 (rank : 147)
Query Neighborhood Hits	171	Target Neighborhood Hits	1069	Shared Neighborhood Hits	15
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

LZTS2_MOUSE
θ value	0.163984 (rank : 47)	NC score	0.025280 (rank : 112)
Query Neighborhood Hits	171	Target Neighborhood Hits	423	Shared Neighborhood Hits	16
SwissProt Accessions	Q91YU6, Q569X6	Gene names	Lzts2, Kiaa1813
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2.

MLL2_HUMAN
θ value	0.163984 (rank : 48)	NC score	0.049176 (rank : 83)
Query Neighborhood Hits	171	Target Neighborhood Hits	1788	Shared Neighborhood Hits	74
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

ROCK2_HUMAN
θ value	0.163984 (rank : 49)	NC score	0.006732 (rank : 165)
Query Neighborhood Hits	171	Target Neighborhood Hits	2073	Shared Neighborhood Hits	28
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

ETV5_MOUSE
θ value	0.21417 (rank : 50)	NC score	0.019265 (rank : 125)
Query Neighborhood Hits	171	Target Neighborhood Hits	328	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

HORN_MOUSE
θ value	0.21417 (rank : 51)	NC score	0.036146 (rank : 94)
Query Neighborhood Hits	171	Target Neighborhood Hits	218	Shared Neighborhood Hits	16
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

PPRB_MOUSE
θ value	0.21417 (rank : 52)	NC score	0.055713 (rank : 65)
Query Neighborhood Hits	171	Target Neighborhood Hits	354	Shared Neighborhood Hits	25
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

SUHW4_MOUSE
θ value	0.21417 (rank : 53)	NC score	0.008510 (rank : 152)
Query Neighborhood Hits	171	Target Neighborhood Hits	737	Shared Neighborhood Hits	10
SwissProt Accessions	Q68FE8, Q3T9B1, Q8BI82	Gene names	Suhw4
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

EXO1_MOUSE
θ value	0.279714 (rank : 54)	NC score	0.049435 (rank : 81)
Query Neighborhood Hits	171	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QZ11, Q3TLM4, Q923A5	Gene names	Exo1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (mExo1) (Exonuclease I).

NCOA6_HUMAN
θ value	0.279714 (rank : 55)	NC score	0.117686 (rank : 39)
Query Neighborhood Hits	171	Target Neighborhood Hits	1202	Shared Neighborhood Hits	75
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

TAOK1_MOUSE
θ value	0.279714 (rank : 56)	NC score	0.005367 (rank : 173)
Query Neighborhood Hits	171	Target Neighborhood Hits	1720	Shared Neighborhood Hits	27
SwissProt Accessions	Q5F2E8, Q69ZL2, Q8JZX2, Q91VG7	Gene names	Taok1, Kiaa1361
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1).

ZIM10_HUMAN
θ value	0.279714 (rank : 57)	NC score	0.045412 (rank : 88)
Query Neighborhood Hits	171	Target Neighborhood Hits	577	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

NOTC2_HUMAN
θ value	0.365318 (rank : 58)	NC score	0.010482 (rank : 144)
Query Neighborhood Hits	171	Target Neighborhood Hits	1113	Shared Neighborhood Hits	21
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

FOXP4_MOUSE
θ value	0.47712 (rank : 59)	NC score	0.017641 (rank : 129)
Query Neighborhood Hits	171	Target Neighborhood Hits	211	Shared Neighborhood Hits	12
SwissProt Accessions	Q9DBY0, Q80V92, Q8CG10, Q8CIS1	Gene names	Foxp4
Domain Architecture	No domain graphic available
Description	Forkhead box protein P4 (Fork head-related protein like A) (mFKHLA).

FUS_HUMAN
θ value	0.47712 (rank : 60)	NC score	0.047011 (rank : 86)
Query Neighborhood Hits	171	Target Neighborhood Hits	179	Shared Neighborhood Hits	22
SwissProt Accessions	P35637	Gene names	FUS, TLS
Domain Architecture
Description	RNA-binding protein FUS (Oncogene FUS) (Oncogene TLS) (Translocated in liposarcoma protein) (POMp75) (75 kDa DNA-pairing protein).

LRC27_HUMAN
θ value	0.47712 (rank : 61)	NC score	0.017404 (rank : 130)
Query Neighborhood Hits	171	Target Neighborhood Hits	710	Shared Neighborhood Hits	18
SwissProt Accessions	Q9C0I9, Q5SZH6, Q5SZH8, Q5SZH9, Q86XT5, Q8N7C8, Q8NA21	Gene names	LRRC27, KIAA1674
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 27.

NFAT5_HUMAN
θ value	0.47712 (rank : 62)	NC score	0.046753 (rank : 87)
Query Neighborhood Hits	171	Target Neighborhood Hits	217	Shared Neighborhood Hits	26
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

PGCA_MOUSE
θ value	0.47712 (rank : 63)	NC score	0.024046 (rank : 117)
Query Neighborhood Hits	171	Target Neighborhood Hits	643	Shared Neighborhood Hits	26
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

SPT5H_HUMAN
θ value	0.47712 (rank : 64)	NC score	0.047391 (rank : 84)
Query Neighborhood Hits	171	Target Neighborhood Hits	436	Shared Neighborhood Hits	34
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	0.47712 (rank : 65)	NC score	0.047161 (rank : 85)
Query Neighborhood Hits	171	Target Neighborhood Hits	437	Shared Neighborhood Hits	34
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

TAOK1_HUMAN
θ value	0.47712 (rank : 66)	NC score	0.005056 (rank : 178)
Query Neighborhood Hits	171	Target Neighborhood Hits	1734	Shared Neighborhood Hits	28
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

N4BP2_HUMAN
θ value	0.62314 (rank : 67)	NC score	0.033380 (rank : 97)
Query Neighborhood Hits	171	Target Neighborhood Hits	107	Shared Neighborhood Hits	7
SwissProt Accessions	Q86UW6, Q9NVK2, Q9P2D4	Gene names	N4BP2, B3BP, KIAA1413
Domain Architecture
Description	NEDD4-binding protein 2 (EC 3.-.-.-) (N4BP2) (BCL-3-binding protein).

NIPBL_HUMAN
θ value	0.62314 (rank : 68)	NC score	0.031964 (rank : 101)
Query Neighborhood Hits	171	Target Neighborhood Hits	1311	Shared Neighborhood Hits	48
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NPBL_MOUSE
θ value	0.62314 (rank : 69)	NC score	0.032019 (rank : 100)
Query Neighborhood Hits	171	Target Neighborhood Hits	1041	Shared Neighborhood Hits	42
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

ZIM10_MOUSE
θ value	0.62314 (rank : 70)	NC score	0.039918 (rank : 91)
Query Neighborhood Hits	171	Target Neighborhood Hits	430	Shared Neighborhood Hits	34
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

BAZ2A_MOUSE
θ value	0.813845 (rank : 71)	NC score	0.035474 (rank : 96)
Query Neighborhood Hits	171	Target Neighborhood Hits	744	Shared Neighborhood Hits	37
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

MYST4_HUMAN
θ value	0.813845 (rank : 72)	NC score	0.028485 (rank : 106)
Query Neighborhood Hits	171	Target Neighborhood Hits	671	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

SSXT_HUMAN
θ value	0.813845 (rank : 73)	NC score	0.069481 (rank : 46)
Query Neighborhood Hits	171	Target Neighborhood Hits	125	Shared Neighborhood Hits	27
SwissProt Accessions	Q15532, Q16404, Q9BXC6	Gene names	SS18, SSXT, SYT
Domain Architecture
Description	SSXT protein (Synovial sarcoma, translocated to X chromosome) (SYT protein).

MAML1_HUMAN
θ value	1.06291 (rank : 74)	NC score	0.052500 (rank : 71)
Query Neighborhood Hits	171	Target Neighborhood Hits	228	Shared Neighborhood Hits	29
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

SSXT_MOUSE
θ value	1.06291 (rank : 75)	NC score	0.067858 (rank : 47)
Query Neighborhood Hits	171	Target Neighborhood Hits	118	Shared Neighborhood Hits	28
SwissProt Accessions	Q62280	Gene names	Ss18, Ssxt, Syt
Domain Architecture
Description	SSXT protein (SYT protein) (Synovial sarcoma-associated Ss18-alpha).

ZBT46_MOUSE
θ value	1.06291 (rank : 76)	NC score	0.004004 (rank : 180)
Query Neighborhood Hits	171	Target Neighborhood Hits	813	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BID6, Q3U2R2, Q9D0G6, Q9D492	Gene names	Zbtb46, Btbd4
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 46 (BTB/POZ domain- containing protein 4).

GAB2_HUMAN
θ value	1.38821 (rank : 77)	NC score	0.017117 (rank : 131)
Query Neighborhood Hits	171	Target Neighborhood Hits	188	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

HORN_HUMAN
θ value	1.38821 (rank : 78)	NC score	0.030909 (rank : 103)
Query Neighborhood Hits	171	Target Neighborhood Hits	206	Shared Neighborhood Hits	15
SwissProt Accessions	Q86YZ3	Gene names	HRNR, S100A18
Domain Architecture	No domain graphic available
Description	Hornerin.

INVO_HUMAN
θ value	1.38821 (rank : 79)	NC score	0.022716 (rank : 119)
Query Neighborhood Hits	171	Target Neighborhood Hits	636	Shared Neighborhood Hits	31
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

K0240_HUMAN
θ value	1.38821 (rank : 80)	NC score	0.029246 (rank : 105)
Query Neighborhood Hits	171	Target Neighborhood Hits	96	Shared Neighborhood Hits	10
SwissProt Accessions	Q6AI39, Q5TFZ3, Q92514	Gene names	KIAA0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

MUC13_MOUSE
θ value	1.38821 (rank : 81)	NC score	0.055532 (rank : 67)
Query Neighborhood Hits	171	Target Neighborhood Hits	447	Shared Neighborhood Hits	27
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

MYST4_MOUSE
θ value	1.38821 (rank : 82)	NC score	0.024470 (rank : 114)
Query Neighborhood Hits	171	Target Neighborhood Hits	416	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

PCDA5_HUMAN
θ value	1.38821 (rank : 83)	NC score	0.003587 (rank : 183)
Query Neighborhood Hits	171	Target Neighborhood Hits	217	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y5H7, O75284, Q8N4R3	Gene names	PCDHA5
Domain Architecture
Description	Protocadherin alpha 5 precursor (PCDH-alpha5).

RBBP6_MOUSE
θ value	1.38821 (rank : 84)	NC score	0.031350 (rank : 102)
Query Neighborhood Hits	171	Target Neighborhood Hits	1014	Shared Neighborhood Hits	28
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

TCF20_HUMAN
θ value	1.38821 (rank : 85)	NC score	0.041869 (rank : 90)
Query Neighborhood Hits	171	Target Neighborhood Hits	323	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

CO7A1_HUMAN
θ value	1.81305 (rank : 86)	NC score	0.006530 (rank : 166)
Query Neighborhood Hits	171	Target Neighborhood Hits	807	Shared Neighborhood Hits	25
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

FUS_MOUSE
θ value	1.81305 (rank : 87)	NC score	0.056318 (rank : 62)
Query Neighborhood Hits	171	Target Neighborhood Hits	154	Shared Neighborhood Hits	15
SwissProt Accessions	P56959	Gene names	Fus
Domain Architecture
Description	RNA-binding protein FUS (Pigpen protein).

PCDA7_HUMAN
θ value	1.81305 (rank : 88)	NC score	0.005096 (rank : 177)
Query Neighborhood Hits	171	Target Neighborhood Hits	221	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UN72, O75282	Gene names	PCDHA7
Domain Architecture
Description	Protocadherin alpha 7 precursor (PCDH-alpha7).

PRD16_HUMAN
θ value	1.81305 (rank : 89)	NC score	0.000772 (rank : 191)
Query Neighborhood Hits	171	Target Neighborhood Hits	832	Shared Neighborhood Hits	15
SwissProt Accessions	Q9HAZ2, Q8WYJ9, Q9C0I8	Gene names	PRDM16, KIAA1675, MEL1, PFM13
Domain Architecture
Description	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1).

RUFY2_HUMAN
θ value	1.81305 (rank : 90)	NC score	0.013659 (rank : 135)
Query Neighborhood Hits	171	Target Neighborhood Hits	1208	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

ABCBB_HUMAN
θ value	2.36792 (rank : 91)	NC score	0.007416 (rank : 162)
Query Neighborhood Hits	171	Target Neighborhood Hits	103	Shared Neighborhood Hits	4
SwissProt Accessions	O95342, Q9UNB2	Gene names	ABCB11, BSEP
Domain Architecture
Description	Bile salt export pump (ATP-binding cassette sub-family B member 11).

ATAD2_HUMAN
θ value	2.36792 (rank : 92)	NC score	0.008686 (rank : 151)
Query Neighborhood Hits	171	Target Neighborhood Hits	322	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

ATX2_MOUSE
θ value	2.36792 (rank : 93)	NC score	0.032960 (rank : 98)
Query Neighborhood Hits	171	Target Neighborhood Hits	445	Shared Neighborhood Hits	31
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

EVI1_HUMAN
θ value	2.36792 (rank : 94)	NC score	0.000199 (rank : 193)
Query Neighborhood Hits	171	Target Neighborhood Hits	924	Shared Neighborhood Hits	17
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.

HDAC4_HUMAN
θ value	2.36792 (rank : 95)	NC score	0.012038 (rank : 142)
Query Neighborhood Hits	171	Target Neighborhood Hits	390	Shared Neighborhood Hits	21
SwissProt Accessions	P56524, Q9UND6	Gene names	HDAC4, KIAA0288
Domain Architecture
Description	Histone deacetylase 4 (HD4).

INP5E_MOUSE
θ value	2.36792 (rank : 96)	NC score	0.013545 (rank : 136)
Query Neighborhood Hits	171	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JII1, Q3TCC9	Gene names	Inpp5e
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

MN1_HUMAN
θ value	2.36792 (rank : 97)	NC score	0.035920 (rank : 95)
Query Neighborhood Hits	171	Target Neighborhood Hits	196	Shared Neighborhood Hits	20
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

PHLPP_HUMAN
θ value	2.36792 (rank : 98)	NC score	0.005469 (rank : 172)
Query Neighborhood Hits	171	Target Neighborhood Hits	604	Shared Neighborhood Hits	18
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

SNX15_MOUSE
θ value	2.36792 (rank : 99)	NC score	0.024819 (rank : 113)
Query Neighborhood Hits	171	Target Neighborhood Hits	62	Shared Neighborhood Hits	5
SwissProt Accessions	Q91WE1	Gene names	Snx15
Domain Architecture	No domain graphic available
Description	Sorting nexin-15.

FRM4A_HUMAN
θ value	3.0926 (rank : 100)	NC score	0.008148 (rank : 153)
Query Neighborhood Hits	171	Target Neighborhood Hits	110	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

GPS2_HUMAN
θ value	3.0926 (rank : 101)	NC score	0.037597 (rank : 92)
Query Neighborhood Hits	171	Target Neighborhood Hits	459	Shared Neighborhood Hits	32
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

LAMC2_MOUSE
θ value	3.0926 (rank : 102)	NC score	0.007060 (rank : 164)
Query Neighborhood Hits	171	Target Neighborhood Hits	614	Shared Neighborhood Hits	10
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

SOX10_HUMAN
θ value	3.0926 (rank : 103)	NC score	0.007935 (rank : 155)
Query Neighborhood Hits	171	Target Neighborhood Hits	122	Shared Neighborhood Hits	9
SwissProt Accessions	P56693	Gene names	SOX10
Domain Architecture
Description	Transcription factor SOX-10.

STK10_MOUSE
θ value	3.0926 (rank : 104)	NC score	0.003151 (rank : 186)
Query Neighborhood Hits	171	Target Neighborhood Hits	2132	Shared Neighborhood Hits	47
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TTLL4_MOUSE
θ value	3.0926 (rank : 105)	NC score	0.012444 (rank : 137)
Query Neighborhood Hits	171	Target Neighborhood Hits	103	Shared Neighborhood Hits	8
SwissProt Accessions	Q80UG8, Q5U4C4	Gene names	Ttll4, Kiaa0173
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 4.

USBP1_MOUSE
θ value	3.0926 (rank : 106)	NC score	0.019767 (rank : 124)
Query Neighborhood Hits	171	Target Neighborhood Hits	115	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R370	Gene names	Ushbp1
Domain Architecture	No domain graphic available
Description	USH1C-binding protein 1 (Usher syndrome type-1C protein-binding protein 1).

WT1_MOUSE
θ value	3.0926 (rank : 107)	NC score	-0.000537 (rank : 195)
Query Neighborhood Hits	171	Target Neighborhood Hits	723	Shared Neighborhood Hits	12
SwissProt Accessions	P22561	Gene names	Wt1, Wt-1
Domain Architecture
Description	Wilms' tumor protein homolog.

ZCHC6_MOUSE
θ value	3.0926 (rank : 108)	NC score	0.012367 (rank : 140)
Query Neighborhood Hits	171	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	Q5BLK4, Q8CIH3	Gene names	Zcchc6
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 6.

BBC3_HUMAN
θ value	4.03905 (rank : 109)	NC score	0.020202 (rank : 123)
Query Neighborhood Hits	171	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BXH1, O00171, Q96PG9	Gene names	BBC3, PUMA
Domain Architecture	No domain graphic available
Description	Bcl-2-binding component 3 (p53 up-regulated modulator of apoptosis) (JFY-1).

COIA1_MOUSE
θ value	4.03905 (rank : 110)	NC score	0.013922 (rank : 134)
Query Neighborhood Hits	171	Target Neighborhood Hits	481	Shared Neighborhood Hits	25
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

GGA2_HUMAN
θ value	4.03905 (rank : 111)	NC score	0.016609 (rank : 132)
Query Neighborhood Hits	171	Target Neighborhood Hits	114	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UJY4, O14564, Q9NYN2, Q9UPS2	Gene names	GGA2, KIAA1080
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear).

HIP1R_MOUSE
θ value	4.03905 (rank : 112)	NC score	0.009220 (rank : 149)
Query Neighborhood Hits	171	Target Neighborhood Hits	959	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

K0552_HUMAN
θ value	4.03905 (rank : 113)	NC score	0.018295 (rank : 128)
Query Neighborhood Hits	171	Target Neighborhood Hits	442	Shared Neighborhood Hits	14
SwissProt Accessions	O60299	Gene names	KIAA0552
Domain Architecture
Description	Protein KIAA0552.

LIPS_HUMAN
θ value	4.03905 (rank : 114)	NC score	0.020374 (rank : 122)
Query Neighborhood Hits	171	Target Neighborhood Hits	314	Shared Neighborhood Hits	21
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

MAML3_HUMAN
θ value	4.03905 (rank : 115)	NC score	0.063901 (rank : 53)
Query Neighborhood Hits	171	Target Neighborhood Hits	323	Shared Neighborhood Hits	41
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

PER3_MOUSE
θ value	4.03905 (rank : 116)	NC score	0.146078 (rank : 33)
Query Neighborhood Hits	171	Target Neighborhood Hits	85	Shared Neighborhood Hits	24
SwissProt Accessions	O70361	Gene names	Per3
Domain Architecture
Description	Period circadian protein 3 (mPER3).

TREF1_MOUSE
θ value	4.03905 (rank : 117)	NC score	0.028204 (rank : 107)
Query Neighborhood Hits	171	Target Neighborhood Hits	682	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

WT1_HUMAN
θ value	4.03905 (rank : 118)	NC score	-0.000704 (rank : 196)
Query Neighborhood Hits	171	Target Neighborhood Hits	720	Shared Neighborhood Hits	12
SwissProt Accessions	P19544, Q15881, Q16256, Q16575, Q8IYZ5	Gene names	WT1
Domain Architecture
Description	Wilms' tumor protein (WT33).

WWP2_HUMAN
θ value	4.03905 (rank : 119)	NC score	0.005798 (rank : 171)
Query Neighborhood Hits	171	Target Neighborhood Hits	177	Shared Neighborhood Hits	10
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

ZF106_MOUSE
θ value	4.03905 (rank : 120)	NC score	0.024253 (rank : 116)
Query Neighborhood Hits	171	Target Neighborhood Hits	472	Shared Neighborhood Hits	21
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

CNOT2_HUMAN
θ value	5.27518 (rank : 121)	NC score	0.018783 (rank : 126)
Query Neighborhood Hits	171	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NZN8, Q9H3E0, Q9NSX5, Q9NWR6, Q9P028	Gene names	CNOT2, CDC36, NOT2
Domain Architecture
Description	CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2).

CNOT2_MOUSE
θ value	5.27518 (rank : 122)	NC score	0.018609 (rank : 127)
Query Neighborhood Hits	171	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C5L3, Q3UE39, Q80YA5, Q9D0P1	Gene names	Cnot2
Domain Architecture
Description	CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2).

CO5A3_HUMAN
θ value	5.27518 (rank : 123)	NC score	0.008731 (rank : 150)
Query Neighborhood Hits	171	Target Neighborhood Hits	433	Shared Neighborhood Hits	21
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

DC1L1_MOUSE
θ value	5.27518 (rank : 124)	NC score	0.009234 (rank : 148)
Query Neighborhood Hits	171	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R1Q8	Gene names	Dync1li1, Dncli1, Dnclic1
Domain Architecture	No domain graphic available
Description	Cytoplasmic dynein 1 light intermediate chain 1 (Dynein light intermediate chain 1, cytosolic) (Dynein light chain A) (DLC-A).

FBX10_HUMAN
θ value	5.27518 (rank : 125)	NC score	0.014885 (rank : 133)
Query Neighborhood Hits	171	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UK96, Q5JRT8, Q9UKC3	Gene names	FBXO10, FBX10
Domain Architecture	No domain graphic available
Description	F-box only protein 10.

HTF4_MOUSE
θ value	5.27518 (rank : 126)	NC score	0.012378 (rank : 139)
Query Neighborhood Hits	171	Target Neighborhood Hits	153	Shared Neighborhood Hits	14
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

ISL1_HUMAN
θ value	5.27518 (rank : 127)	NC score	0.003634 (rank : 181)
Query Neighborhood Hits	171	Target Neighborhood Hits	421	Shared Neighborhood Hits	5
SwissProt Accessions	P61371, P20663, P47894	Gene names	ISL1
Domain Architecture
Description	Insulin gene enhancer protein ISL-1 (Islet-1).

ISL1_MOUSE
θ value	5.27518 (rank : 128)	NC score	0.003634 (rank : 182)
Query Neighborhood Hits	171	Target Neighborhood Hits	421	Shared Neighborhood Hits	5
SwissProt Accessions	P61372, P20663, P47894, Q812D8	Gene names	Isl1
Domain Architecture
Description	Insulin gene enhancer protein ISL-1 (Islet-1).

P73L_HUMAN
θ value	5.27518 (rank : 129)	NC score	0.020743 (rank : 121)
Query Neighborhood Hits	171	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H3D4, O75080, O75195, O75922, O76078, Q6VEG2, Q6VEG3, Q6VEG4, Q6VFJ1, Q6VFJ2, Q6VFJ3, Q6VH20, Q7LDI3, Q7LDI4, Q7LDI5, Q96KR0, Q9H3D2, Q9H3D3, Q9H3P8, Q9NPH7, Q9P1B4, Q9P1B5, Q9P1B6, Q9P1B7, Q9UBV9, Q9UE10, Q9UP26, Q9UP27, Q9UP28, Q9UP74	Gene names	TP73L, KET, P63, P73H, P73L
Domain Architecture	No domain graphic available
Description	Tumor protein p73-like (p73L) (p63) (Tumor protein 63) (TP63) (p51) (p40) (Keratinocyte transcription factor KET) (Chronic ulcerative stomatitis protein) (CUSP).

PER3_HUMAN
θ value	5.27518 (rank : 130)	NC score	0.138942 (rank : 35)
Query Neighborhood Hits	171	Target Neighborhood Hits	479	Shared Neighborhood Hits	45
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

RPTN_MOUSE
θ value	5.27518 (rank : 131)	NC score	0.030130 (rank : 104)
Query Neighborhood Hits	171	Target Neighborhood Hits	650	Shared Neighborhood Hits	46
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

SFPQ_HUMAN
θ value	5.27518 (rank : 132)	NC score	0.024392 (rank : 115)
Query Neighborhood Hits	171	Target Neighborhood Hits	986	Shared Neighborhood Hits	49
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

ST1C1_MOUSE
θ value	5.27518 (rank : 133)	NC score	0.004589 (rank : 179)
Query Neighborhood Hits	171	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q80VR3, O70262	Gene names	Sult1c1, Sult1a2
Domain Architecture	No domain graphic available
Description	Sulfotransferase 1C1 (EC 2.8.2.-) (Phenol sulfotransferase).

TFE2_MOUSE
θ value	5.27518 (rank : 134)	NC score	0.012285 (rank : 141)
Query Neighborhood Hits	171	Target Neighborhood Hits	118	Shared Neighborhood Hits	8
SwissProt Accessions	P15806, Q3U153, Q8CAH9, Q8VCY4, Q922S2, Q99MB8, Q9CYJ4	Gene names	Tcf3, Alf2, Me2, Tcfe2a
Domain Architecture	No domain graphic available
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Transcription factor A1).

ALMS1_MOUSE
θ value	6.88961 (rank : 135)	NC score	0.011913 (rank : 143)
Query Neighborhood Hits	171	Target Neighborhood Hits	181	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K4E0, Q6A084, Q8C9N9	Gene names	Alms1, Kiaa0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1 homolog.

APOA5_HUMAN
θ value	6.88961 (rank : 136)	NC score	0.009879 (rank : 146)
Query Neighborhood Hits	171	Target Neighborhood Hits	104	Shared Neighborhood Hits	5
SwissProt Accessions	Q6Q788, Q6UWK9, Q9UBJ3	Gene names	APOA5, RAP3
Domain Architecture	No domain graphic available
Description	Apolipoprotein A-V precursor (Apolipoprotein A5) (ApoAV) (ApoA-V) (Regeneration-associated protein 3).

CSTF2_HUMAN
θ value	6.88961 (rank : 137)	NC score	0.006456 (rank : 167)
Query Neighborhood Hits	171	Target Neighborhood Hits	296	Shared Neighborhood Hits	13
SwissProt Accessions	P33240, Q5H951, Q6LA74, Q8N502	Gene names	CSTF2
Domain Architecture
Description	Cleavage stimulation factor 64 kDa subunit (CSTF 64 kDa subunit) (CF-1 64 kDa subunit) (CstF-64).

EAN57_HUMAN
θ value	6.88961 (rank : 138)	NC score	0.012431 (rank : 138)
Query Neighborhood Hits	171	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	O43247, Q6ICF2, Q9Y4V8	Gene names	EAN57
Domain Architecture	No domain graphic available
Description	Protein EAN57.

GPTC8_HUMAN
θ value	6.88961 (rank : 139)	NC score	0.023091 (rank : 118)
Query Neighborhood Hits	171	Target Neighborhood Hits	366	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

KAISO_MOUSE
θ value	6.88961 (rank : 140)	NC score	-0.000289 (rank : 194)
Query Neighborhood Hits	171	Target Neighborhood Hits	821	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BN78, Q8C226, Q9WTZ7	Gene names	Zbtb33, Kaiso
Domain Architecture	No domain graphic available
Description	Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33).

MDR3_MOUSE
θ value	6.88961 (rank : 141)	NC score	0.006111 (rank : 169)
Query Neighborhood Hits	171	Target Neighborhood Hits	106	Shared Neighborhood Hits	5
SwissProt Accessions	P21447	Gene names	Abcb1a, Abcb4, Mdr1a, Mdr3, Pgy-3, Pgy3
Domain Architecture
Description	Multidrug resistance protein 3 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1A) (P-glycoprotein 3) (MDR1A).

NKX61_MOUSE
θ value	6.88961 (rank : 142)	NC score	0.002787 (rank : 188)
Query Neighborhood Hits	171	Target Neighborhood Hits	439	Shared Neighborhood Hits	12
SwissProt Accessions	Q99MA9, Q9ERQ7	Gene names	Nkx6-1, Nkx6.1, Nkx6a
Domain Architecture
Description	Homeobox protein Nkx-6.1.

NUCB1_HUMAN
θ value	6.88961 (rank : 143)	NC score	0.007627 (rank : 159)
Query Neighborhood Hits	171	Target Neighborhood Hits	359	Shared Neighborhood Hits	12
SwissProt Accessions	Q02818, Q15838, Q7Z4J7, Q9BUR1	Gene names	NUCB1, NUC
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

R3HD1_HUMAN
θ value	6.88961 (rank : 144)	NC score	0.025806 (rank : 111)
Query Neighborhood Hits	171	Target Neighborhood Hits	203	Shared Neighborhood Hits	23
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

SRRM2_MOUSE
θ value	6.88961 (rank : 145)	NC score	0.056895 (rank : 60)
Query Neighborhood Hits	171	Target Neighborhood Hits	1470	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

T3JAM_HUMAN
θ value	6.88961 (rank : 146)	NC score	0.006367 (rank : 168)
Query Neighborhood Hits	171	Target Neighborhood Hits	533	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

TCF20_MOUSE
θ value	6.88961 (rank : 147)	NC score	0.037302 (rank : 93)
Query Neighborhood Hits	171	Target Neighborhood Hits	396	Shared Neighborhood Hits	41
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

UBN1_HUMAN
θ value	6.88961 (rank : 148)	NC score	0.020968 (rank : 120)
Query Neighborhood Hits	171	Target Neighborhood Hits	170	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NPG3, Q13079, Q9P1P7	Gene names	UBN1
Domain Architecture	No domain graphic available
Description	Ubinuclein (Ubiquitously expressed nuclear protein) (VT4).

ZBT46_HUMAN
θ value	6.88961 (rank : 149)	NC score	0.000761 (rank : 192)
Query Neighborhood Hits	171	Target Neighborhood Hits	813	Shared Neighborhood Hits	12
SwissProt Accessions	Q86UZ6, Q5JWJ3, Q9BQK3, Q9H3Z8, Q9H3Z9	Gene names	ZBTB46, BTBD4, ZNF340
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 46 (BTB/POZ domain- containing protein 4) (Zinc finger protein 340).

ZNFX1_MOUSE
θ value	6.88961 (rank : 150)	NC score	0.005849 (rank : 170)
Query Neighborhood Hits	171	Target Neighborhood Hits	407	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ANDR_MOUSE
θ value	8.99809 (rank : 151)	NC score	0.008034 (rank : 154)
Query Neighborhood Hits	171	Target Neighborhood Hits	133	Shared Neighborhood Hits	8
SwissProt Accessions	P19091	Gene names	Ar, Nr3c4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

ARHG9_HUMAN
θ value	8.99809 (rank : 152)	NC score	0.005275 (rank : 176)
Query Neighborhood Hits	171	Target Neighborhood Hits	235	Shared Neighborhood Hits	4
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

ARHG9_MOUSE
θ value	8.99809 (rank : 153)	NC score	0.005287 (rank : 174)
Query Neighborhood Hits	171	Target Neighborhood Hits	234	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

AT2B2_HUMAN
θ value	8.99809 (rank : 154)	NC score	0.003561 (rank : 184)
Query Neighborhood Hits	171	Target Neighborhood Hits	75	Shared Neighborhood Hits	4
SwissProt Accessions	Q01814, O00766, Q12994, Q16818	Gene names	ATP2B2, PMCA2
Domain Architecture
Description	Plasma membrane calcium-transporting ATPase 2 (EC 3.6.3.8) (PMCA2) (Plasma membrane calcium pump isoform 2) (Plasma membrane calcium ATPase isoform 2).

AT2B2_MOUSE
θ value	8.99809 (rank : 155)	NC score	0.003387 (rank : 185)
Query Neighborhood Hits	171	Target Neighborhood Hits	68	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R0K7, O88863	Gene names	Atp2b2, Pmca2
Domain Architecture
Description	Plasma membrane calcium-transporting ATPase 2 (EC 3.6.3.8) (PMCA2) (Plasma membrane calcium pump isoform 2) (Plasma membrane calcium ATPase isoform 2).

BMP2K_MOUSE
θ value	8.99809 (rank : 156)	NC score	0.001785 (rank : 190)
Query Neighborhood Hits	171	Target Neighborhood Hits	874	Shared Neighborhood Hits	17
SwissProt Accessions	Q91Z96, Q8C8L7	Gene names	Bmp2k, Bike
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

BTBD9_MOUSE
θ value	8.99809 (rank : 157)	NC score	0.002989 (rank : 187)
Query Neighborhood Hits	171	Target Neighborhood Hits	165	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C726	Gene names	Btbd9
Domain Architecture
Description	BTB/POZ domain-containing protein 9.

EMSY_HUMAN
θ value	8.99809 (rank : 158)	NC score	0.027233 (rank : 110)
Query Neighborhood Hits	171	Target Neighborhood Hits	296	Shared Neighborhood Hits	29
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

FOXN1_MOUSE
θ value	8.99809 (rank : 159)	NC score	0.007541 (rank : 160)
Query Neighborhood Hits	171	Target Neighborhood Hits	300	Shared Neighborhood Hits	22
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

FXR2_MOUSE
θ value	8.99809 (rank : 160)	NC score	0.007704 (rank : 157)
Query Neighborhood Hits	171	Target Neighborhood Hits	66	Shared Neighborhood Hits	9
SwissProt Accessions	Q9WVR4, Q9WVR5	Gene names	Fxr2, Fxr2h
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

GO45_MOUSE
θ value	8.99809 (rank : 161)	NC score	0.007754 (rank : 156)
Query Neighborhood Hits	171	Target Neighborhood Hits	139	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R2X8, Q3TJC4, Q8C0U6, Q9DAV7	Gene names	Blzf1
Domain Architecture	No domain graphic available
Description	Golgin 45 (Basic leucine zipper nuclear factor 1).

HES7_HUMAN
θ value	8.99809 (rank : 162)	NC score	0.051778 (rank : 76)
Query Neighborhood Hits	171	Target Neighborhood Hits	72	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BYE0	Gene names	HES7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

HES7_MOUSE
θ value	8.99809 (rank : 163)	NC score	0.049249 (rank : 82)
Query Neighborhood Hits	171	Target Neighborhood Hits	72	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BKT2, Q99JA6	Gene names	Hes7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

MAML2_HUMAN
θ value	8.99809 (rank : 164)	NC score	0.078930 (rank : 42)
Query Neighborhood Hits	171	Target Neighborhood Hits	360	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

MAST2_HUMAN
θ value	8.99809 (rank : 165)	NC score	0.002049 (rank : 189)
Query Neighborhood Hits	171	Target Neighborhood Hits	1189	Shared Neighborhood Hits	18
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MDR1_MOUSE
θ value	8.99809 (rank : 166)	NC score	0.005279 (rank : 175)
Query Neighborhood Hits	171	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	P06795	Gene names	Abcb1, Abcb1b, Mdr1, Mdr1b, Pgy1, Pgy1-1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).

MLL3_MOUSE
θ value	8.99809 (rank : 167)	NC score	0.042138 (rank : 89)
Query Neighborhood Hits	171	Target Neighborhood Hits	1399	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NEST_HUMAN
θ value	8.99809 (rank : 168)	NC score	0.009902 (rank : 145)
Query Neighborhood Hits	171	Target Neighborhood Hits	1305	Shared Neighborhood Hits	34
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

RPTN_HUMAN
θ value	8.99809 (rank : 169)	NC score	0.027466 (rank : 108)
Query Neighborhood Hits	171	Target Neighborhood Hits	406	Shared Neighborhood Hits	27
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

SC6A5_MOUSE
θ value	8.99809 (rank : 170)	NC score	0.007627 (rank : 158)
Query Neighborhood Hits	171	Target Neighborhood Hits	135	Shared Neighborhood Hits	6
SwissProt Accessions	Q761V0, Q8CFM5, Q91ZQ2	Gene names	Slc6a5, Glyt2
Domain Architecture	No domain graphic available
Description	Sodium- and chloride-dependent glycine transporter 2 (GlyT2) (GlyT-2) (Solute carrier family 6 member 5).

TNR6A_HUMAN
θ value	8.99809 (rank : 171)	NC score	0.027392 (rank : 109)
Query Neighborhood Hits	171	Target Neighborhood Hits	343	Shared Neighborhood Hits	30
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

ARI1B_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.051103 (rank : 77)
Query Neighborhood Hits	171	Target Neighborhood Hits	567	Shared Neighborhood Hits	46
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

ATN1_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.052845 (rank : 70)
Query Neighborhood Hits	171	Target Neighborhood Hits	676	Shared Neighborhood Hits	45
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BCL9_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.053707 (rank : 69)
Query Neighborhood Hits	171	Target Neighborhood Hits	1008	Shared Neighborhood Hits	47
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

HEY1_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.064489 (rank : 51)
Query Neighborhood Hits	171	Target Neighborhood Hits	82	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

HEY1_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.067458 (rank : 49)
Query Neighborhood Hits	171	Target Neighborhood Hits	69	Shared Neighborhood Hits	20
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

HEY2_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.072306 (rank : 44)
Query Neighborhood Hits	171	Target Neighborhood Hits	77	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY2_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.070662 (rank : 45)
Query Neighborhood Hits	171	Target Neighborhood Hits	80	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

MITF_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.066361 (rank : 50)
Query Neighborhood Hits	171	Target Neighborhood Hits	113	Shared Neighborhood Hits	17
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MITF_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.067541 (rank : 48)
Query Neighborhood Hits	171	Target Neighborhood Hits	115	Shared Neighborhood Hits	16
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MLX_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.060993 (rank : 54)
Query Neighborhood Hits	171	Target Neighborhood Hits	95	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.060957 (rank : 55)
Query Neighborhood Hits	171	Target Neighborhood Hits	100	Shared Neighborhood Hits	13
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

PER1_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.143416 (rank : 34)
Query Neighborhood Hits	171	Target Neighborhood Hits	215	Shared Neighborhood Hits	38
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PER1_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.131575 (rank : 37)
Query Neighborhood Hits	171	Target Neighborhood Hits	235	Shared Neighborhood Hits	36
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

PER2_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.132238 (rank : 36)
Query Neighborhood Hits	171	Target Neighborhood Hits	170	Shared Neighborhood Hits	29
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

PER2_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.122852 (rank : 38)
Query Neighborhood Hits	171	Target Neighborhood Hits	325	Shared Neighborhood Hits	27
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

PPRB_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.056578 (rank : 61)
Query Neighborhood Hits	171	Target Neighborhood Hits	311	Shared Neighborhood Hits	25
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

PRP2_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.052364 (rank : 72)
Query Neighborhood Hits	171	Target Neighborhood Hits	347	Shared Neighborhood Hits	27
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

TCFL5_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.059109 (rank : 57)
Query Neighborhood Hits	171	Target Neighborhood Hits	43	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

TFE3_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.056073 (rank : 63)
Query Neighborhood Hits	171	Target Neighborhood Hits	190	Shared Neighborhood Hits	13
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

TFEB_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.052152 (rank : 75)
Query Neighborhood Hits	171	Target Neighborhood Hits	111	Shared Neighborhood Hits	13
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

TFEB_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.054129 (rank : 68)
Query Neighborhood Hits	171	Target Neighborhood Hits	119	Shared Neighborhood Hits	19
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

USF1_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.052237 (rank : 73)
Query Neighborhood Hits	171	Target Neighborhood Hits	70	Shared Neighborhood Hits	8
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.052212 (rank : 74)
Query Neighborhood Hits	171	Target Neighborhood Hits	71	Shared Neighborhood Hits	8
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF2_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.050448 (rank : 80)
Query Neighborhood Hits	171	Target Neighborhood Hits	155	Shared Neighborhood Hits	8
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

YLPM1_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.050453 (rank : 79)
Query Neighborhood Hits	171	Target Neighborhood Hits	670	Shared Neighborhood Hits	48
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

Hits sorted by NC score

NCOA3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	171	Target Neighborhood Hits	171	Shared Neighborhood Hits	171
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

NCOA3_MOUSE
NC score	0.966968 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	171	Target Neighborhood Hits	203	Shared Neighborhood Hits	63
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

NCOA2_HUMAN
NC score	0.934324 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	171	Target Neighborhood Hits	281	Shared Neighborhood Hits	56
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

NCOA2_MOUSE
NC score	0.932488 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	171	Target Neighborhood Hits	281	Shared Neighborhood Hits	53
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

NCOA1_MOUSE
NC score	0.912004 (rank : 5)	θ value	2.36115e-125 (rank : 6)
Query Neighborhood Hits	171	Target Neighborhood Hits	196	Shared Neighborhood Hits	47
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

NCOA1_HUMAN
NC score	0.910960 (rank : 6)	θ value	3.5201e-129 (rank : 5)
Query Neighborhood Hits	171	Target Neighborhood Hits	198	Shared Neighborhood Hits	43
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

CLOCK_MOUSE
NC score	0.605117 (rank : 7)	θ value	9.90251e-15 (rank : 11)
Query Neighborhood Hits	171	Target Neighborhood Hits	148	Shared Neighborhood Hits	44
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

BMAL1_HUMAN
NC score	0.604957 (rank : 8)	θ value	2.5182e-18 (rank : 8)
Query Neighborhood Hits	171	Target Neighborhood Hits	115	Shared Neighborhood Hits	38
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
NC score	0.603881 (rank : 9)	θ value	5.07402e-19 (rank : 7)
Query Neighborhood Hits	171	Target Neighborhood Hits	121	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

CLOCK_HUMAN
NC score	0.602801 (rank : 10)	θ value	1.68911e-14 (rank : 12)
Query Neighborhood Hits	171	Target Neighborhood Hits	127	Shared Neighborhood Hits	42
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

AHR_HUMAN
NC score	0.589777 (rank : 11)	θ value	3.52202e-12 (rank : 16)
Query Neighborhood Hits	171	Target Neighborhood Hits	47	Shared Neighborhood Hits	34
SwissProt Accessions	P35869, Q13728, Q13803, Q13804	Gene names	AHR
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

AHR_MOUSE
NC score	0.582022 (rank : 12)	θ value	2.0648e-12 (rank : 15)
Query Neighborhood Hits	171	Target Neighborhood Hits	55	Shared Neighborhood Hits	36
SwissProt Accessions	P30561, Q8QZX6, Q8R4S3, Q99P79, Q9QVY1	Gene names	Ahr
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

ARNT2_MOUSE
NC score	0.575044 (rank : 13)	θ value	4.44505e-15 (rank : 9)
Query Neighborhood Hits	171	Target Neighborhood Hits	115	Shared Neighborhood Hits	36
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_HUMAN
NC score	0.574792 (rank : 14)	θ value	5.8054e-15 (rank : 10)
Query Neighborhood Hits	171	Target Neighborhood Hits	109	Shared Neighborhood Hits	35
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

NPAS2_MOUSE
NC score	0.572833 (rank : 15)	θ value	2.13673e-09 (rank : 24)
Query Neighborhood Hits	171	Target Neighborhood Hits	132	Shared Neighborhood Hits	45
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

EPAS1_MOUSE
NC score	0.569862 (rank : 16)	θ value	7.84624e-12 (rank : 17)
Query Neighborhood Hits	171	Target Neighborhood Hits	94	Shared Neighborhood Hits	38
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

NPAS2_HUMAN
NC score	0.569420 (rank : 17)	θ value	3.64472e-09 (rank : 25)
Query Neighborhood Hits	171	Target Neighborhood Hits	150	Shared Neighborhood Hits	42
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

HIF1A_MOUSE
NC score	0.566854 (rank : 18)	θ value	6.64225e-11 (rank : 19)
Query Neighborhood Hits	171	Target Neighborhood Hits	90	Shared Neighborhood Hits	39
SwissProt Accessions	Q61221, O08741, O08993, Q61664, Q61665, Q8C681, Q8CC19, Q8CCB6, Q8R385, Q9CYA8	Gene names	Hif1a
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein).

EPAS1_HUMAN
NC score	0.566111 (rank : 19)	θ value	2.28291e-11 (rank : 18)
Query Neighborhood Hits	171	Target Neighborhood Hits	76	Shared Neighborhood Hits	35
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

HIF1A_HUMAN
NC score	0.565466 (rank : 20)	θ value	1.47974e-10 (rank : 20)
Query Neighborhood Hits	171	Target Neighborhood Hits	118	Shared Neighborhood Hits	37
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

ARNT_HUMAN
NC score	0.563631 (rank : 21)	θ value	6.41864e-14 (rank : 13)
Query Neighborhood Hits	171	Target Neighborhood Hits	109	Shared Neighborhood Hits	37
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

SIM1_HUMAN
NC score	0.562303 (rank : 22)	θ value	4.30538e-10 (rank : 22)
Query Neighborhood Hits	171	Target Neighborhood Hits	62	Shared Neighborhood Hits	36
SwissProt Accessions	P81133, Q5TDP7	Gene names	SIM1
Domain Architecture
Description	Single-minded homolog 1.

SIM1_MOUSE
NC score	0.561427 (rank : 23)	θ value	4.30538e-10 (rank : 23)
Query Neighborhood Hits	171	Target Neighborhood Hits	69	Shared Neighborhood Hits	36
SwissProt Accessions	Q61045, O70284, P70183	Gene names	Sim1
Domain Architecture
Description	Single-minded homolog 1 (mSIM1).

SIM2_MOUSE
NC score	0.555783 (rank : 24)	θ value	3.29651e-10 (rank : 21)
Query Neighborhood Hits	171	Target Neighborhood Hits	75	Shared Neighborhood Hits	34
SwissProt Accessions	Q61079, O35391, Q61046, Q61904	Gene names	Sim2
Domain Architecture
Description	Single-minded homolog 2 (SIM transcription factor) (mSIM).

ARNT_MOUSE
NC score	0.555782 (rank : 25)	θ value	4.16044e-13 (rank : 14)
Query Neighborhood Hits	171	Target Neighborhood Hits	213	Shared Neighborhood Hits	45
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

SIM2_HUMAN
NC score	0.553234 (rank : 26)	θ value	1.38499e-08 (rank : 26)
Query Neighborhood Hits	171	Target Neighborhood Hits	76	Shared Neighborhood Hits	35
SwissProt Accessions	Q14190, O60766, Q15470, Q15471, Q15472, Q15473, Q16532	Gene names	SIM2
Domain Architecture
Description	Single-minded homolog 2.

NPAS1_MOUSE
NC score	0.537310 (rank : 27)	θ value	6.87365e-08 (rank : 27)
Query Neighborhood Hits	171	Target Neighborhood Hits	63	Shared Neighborhood Hits	35
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).

NPAS1_HUMAN
NC score	0.527169 (rank : 28)	θ value	2.61198e-07 (rank : 28)
Query Neighborhood Hits	171	Target Neighborhood Hits	77	Shared Neighborhood Hits	34
SwissProt Accessions	Q99742, Q99632, Q9BY83	Gene names	NPAS1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1) (Member of PAS protein 5) (MOP5).

NPAS3_MOUSE
NC score	0.524212 (rank : 29)	θ value	7.59969e-07 (rank : 30)
Query Neighborhood Hits	171	Target Neighborhood Hits	103	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QZQ0, Q9EQP4	Gene names	Npas3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

NPAS3_HUMAN
NC score	0.521640 (rank : 30)	θ value	7.59969e-07 (rank : 29)
Query Neighborhood Hits	171	Target Neighborhood Hits	81	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IXF0, Q86US6, Q86US7, Q8IXF2, Q9BY81, Q9H323, Q9Y4L8	Gene names	NPAS3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

NPAS4_HUMAN
NC score	0.364593 (rank : 31)	θ value	0.0252991 (rank : 38)
Query Neighborhood Hits	171	Target Neighborhood Hits	214	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

NPAS4_MOUSE
NC score	0.357377 (rank : 32)	θ value	0.0252991 (rank : 39)
Query Neighborhood Hits	171	Target Neighborhood Hits	245	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

PER3_MOUSE
NC score	0.146078 (rank : 33)	θ value	4.03905 (rank : 116)
Query Neighborhood Hits	171	Target Neighborhood Hits	85	Shared Neighborhood Hits	24
SwissProt Accessions	O70361	Gene names	Per3
Domain Architecture
Description	Period circadian protein 3 (mPER3).

PER1_HUMAN
NC score	0.143416 (rank : 34)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	171	Target Neighborhood Hits	215	Shared Neighborhood Hits	38
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PER3_HUMAN
NC score	0.138942 (rank : 35)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	171	Target Neighborhood Hits	479	Shared Neighborhood Hits	45
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PER2_HUMAN
NC score	0.132238 (rank : 36)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	171	Target Neighborhood Hits	170	Shared Neighborhood Hits	29
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

PER1_MOUSE
NC score	0.131575 (rank : 37)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	171	Target Neighborhood Hits	235	Shared Neighborhood Hits	36
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

PER2_MOUSE
NC score	0.122852 (rank : 38)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	171	Target Neighborhood Hits	325	Shared Neighborhood Hits	27
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

NCOA6_HUMAN
NC score	0.117686 (rank : 39)	θ value	0.279714 (rank : 55)
Query Neighborhood Hits	171	Target Neighborhood Hits	1202	Shared Neighborhood Hits	75
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NCOA6_MOUSE
NC score	0.115727 (rank : 40)	θ value	0.0736092 (rank : 43)
Query Neighborhood Hits	171	Target Neighborhood Hits	1076	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

ARI1A_HUMAN
NC score	0.084330 (rank : 41)	θ value	0.0330416 (rank : 41)
Query Neighborhood Hits	171	Target Neighborhood Hits	787	Shared Neighborhood Hits	58
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

MAML2_HUMAN
NC score	0.078930 (rank : 42)	θ value	8.99809 (rank : 164)
Query Neighborhood Hits	171	Target Neighborhood Hits	360	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

HGS_HUMAN
NC score	0.074741 (rank : 43)	θ value	0.00390308 (rank : 31)
Query Neighborhood Hits	171	Target Neighborhood Hits	517	Shared Neighborhood Hits	33
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

HEY2_HUMAN
NC score	0.072306 (rank : 44)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	171	Target Neighborhood Hits	77	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY2_MOUSE
NC score	0.070662 (rank : 45)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	171	Target Neighborhood Hits	80	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

SSXT_HUMAN
NC score	0.069481 (rank : 46)	θ value	0.813845 (rank : 73)
Query Neighborhood Hits	171	Target Neighborhood Hits	125	Shared Neighborhood Hits	27
SwissProt Accessions	Q15532, Q16404, Q9BXC6	Gene names	SS18, SSXT, SYT
Domain Architecture
Description	SSXT protein (Synovial sarcoma, translocated to X chromosome) (SYT protein).

SSXT_MOUSE
NC score	0.067858 (rank : 47)	θ value	1.06291 (rank : 75)
Query Neighborhood Hits	171	Target Neighborhood Hits	118	Shared Neighborhood Hits	28
SwissProt Accessions	Q62280	Gene names	Ss18, Ssxt, Syt
Domain Architecture
Description	SSXT protein (SYT protein) (Synovial sarcoma-associated Ss18-alpha).

MITF_MOUSE
NC score	0.067541 (rank : 48)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	171	Target Neighborhood Hits	115	Shared Neighborhood Hits	16
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

HEY1_MOUSE
NC score	0.067458 (rank : 49)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	171	Target Neighborhood Hits	69	Shared Neighborhood Hits	20
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

MITF_HUMAN
NC score	0.066361 (rank : 50)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	171	Target Neighborhood Hits	113	Shared Neighborhood Hits	17
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

HEY1_HUMAN
NC score	0.064489 (rank : 51)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	171	Target Neighborhood Hits	82	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

EP300_HUMAN
NC score	0.064119 (rank : 52)	θ value	0.0431538 (rank : 42)
Query Neighborhood Hits	171	Target Neighborhood Hits	821	Shared Neighborhood Hits	63
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

MAML3_HUMAN
NC score	0.063901 (rank : 53)	θ value	4.03905 (rank : 115)
Query Neighborhood Hits	171	Target Neighborhood Hits	323	Shared Neighborhood Hits	41
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

MLX_HUMAN
NC score	0.060993 (rank : 54)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	171	Target Neighborhood Hits	95	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_MOUSE
NC score	0.060957 (rank : 55)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	171	Target Neighborhood Hits	100	Shared Neighborhood Hits	13
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

TEX15_HUMAN
NC score	0.059380 (rank : 56)	θ value	0.0193708 (rank : 36)
Query Neighborhood Hits	171	Target Neighborhood Hits	174	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BXT5	Gene names	TEX15
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 15 protein.

TCFL5_HUMAN
NC score	0.059109 (rank : 57)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	171	Target Neighborhood Hits	43	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

SSBP3_HUMAN
NC score	0.057454 (rank : 58)	θ value	0.0193708 (rank : 34)
Query Neighborhood Hits	171	Target Neighborhood Hits	132	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BWW4, Q9BTM0, Q9BWW3	Gene names	SSBP3, SSDP, SSDP1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein).

SSBP3_MOUSE
NC score	0.057454 (rank : 59)	θ value	0.0193708 (rank : 35)
Query Neighborhood Hits	171	Target Neighborhood Hits	132	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D032, Q99LC6, Q9EQP3	Gene names	Ssbp3, Last, Ssdp1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein) (Lck-associated signal transducer).

SRRM2_MOUSE
NC score	0.056895 (rank : 60)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	171	Target Neighborhood Hits	1470	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

PPRB_HUMAN
NC score	0.056578 (rank : 61)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	171	Target Neighborhood Hits	311	Shared Neighborhood Hits	25
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

FUS_MOUSE
NC score	0.056318 (rank : 62)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	171	Target Neighborhood Hits	154	Shared Neighborhood Hits	15
SwissProt Accessions	P56959	Gene names	Fus
Domain Architecture
Description	RNA-binding protein FUS (Pigpen protein).

TFE3_HUMAN
NC score	0.056073 (rank : 63)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	171	Target Neighborhood Hits	190	Shared Neighborhood Hits	13
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

HGS_MOUSE
NC score	0.055896 (rank : 64)	θ value	0.0148317 (rank : 33)
Query Neighborhood Hits	171	Target Neighborhood Hits	589	Shared Neighborhood Hits	29
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

PPRB_MOUSE
NC score	0.055713 (rank : 65)	θ value	0.21417 (rank : 52)
Query Neighborhood Hits	171	Target Neighborhood Hits	354	Shared Neighborhood Hits	25
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

NFAT5_MOUSE
NC score	0.055581 (rank : 66)	θ value	0.0252991 (rank : 37)
Query Neighborhood Hits	171	Target Neighborhood Hits	162	Shared Neighborhood Hits	17
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

MUC13_MOUSE
NC score	0.055532 (rank : 67)	θ value	1.38821 (rank : 81)
Query Neighborhood Hits	171	Target Neighborhood Hits	447	Shared Neighborhood Hits	27
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

TFEB_MOUSE
NC score	0.054129 (rank : 68)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	171	Target Neighborhood Hits	119	Shared Neighborhood Hits	19
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

BCL9_HUMAN
NC score	0.053707 (rank : 69)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	171	Target Neighborhood Hits	1008	Shared Neighborhood Hits	47
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

ATN1_HUMAN
NC score	0.052845 (rank : 70)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	171	Target Neighborhood Hits	676	Shared Neighborhood Hits	45
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

MAML1_HUMAN
NC score	0.052500 (rank : 71)	θ value	1.06291 (rank : 74)
Query Neighborhood Hits	171	Target Neighborhood Hits	228	Shared Neighborhood Hits	29
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

PRP2_MOUSE
NC score	0.052364 (rank : 72)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	171	Target Neighborhood Hits	347	Shared Neighborhood Hits	27
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

USF1_HUMAN
NC score	0.052237 (rank : 73)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	171	Target Neighborhood Hits	70	Shared Neighborhood Hits	8
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_MOUSE
NC score	0.052212 (rank : 74)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	171	Target Neighborhood Hits	71	Shared Neighborhood Hits	8
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

TFEB_HUMAN
NC score	0.052152 (rank : 75)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	171	Target Neighborhood Hits	111	Shared Neighborhood Hits	13
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

HES7_HUMAN
NC score	0.051778 (rank : 76)	θ value	8.99809 (rank : 162)
Query Neighborhood Hits	171	Target Neighborhood Hits	72	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BYE0	Gene names	HES7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

ARI1B_HUMAN
NC score	0.051103 (rank : 77)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	171	Target Neighborhood Hits	567	Shared Neighborhood Hits	46
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

MLL3_HUMAN
NC score	0.051073 (rank : 78)	θ value	0.00869519 (rank : 32)
Query Neighborhood Hits	171	Target Neighborhood Hits	1644	Shared Neighborhood Hits	73
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

YLPM1_HUMAN
NC score	0.050453 (rank : 79)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	171	Target Neighborhood Hits	670	Shared Neighborhood Hits	48
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

USF2_HUMAN
NC score	0.050448 (rank : 80)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	171	Target Neighborhood Hits	155	Shared Neighborhood Hits	8
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

EXO1_MOUSE
NC score	0.049435 (rank : 81)	θ value	0.279714 (rank : 54)
Query Neighborhood Hits	171	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QZ11, Q3TLM4, Q923A5	Gene names	Exo1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (mExo1) (Exonuclease I).

HES7_MOUSE
NC score	0.049249 (rank : 82)	θ value	8.99809 (rank : 163)
Query Neighborhood Hits	171	Target Neighborhood Hits	72	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BKT2, Q99JA6	Gene names	Hes7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

MLL2_HUMAN
NC score	0.049176 (rank : 83)	θ value	0.163984 (rank : 48)
Query Neighborhood Hits	171	Target Neighborhood Hits	1788	Shared Neighborhood Hits	74
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

SPT5H_HUMAN
NC score	0.047391 (rank : 84)	θ value	0.47712 (rank : 64)
Query Neighborhood Hits	171	Target Neighborhood Hits	436	Shared Neighborhood Hits	34
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
NC score	0.047161 (rank : 85)	θ value	0.47712 (rank : 65)
Query Neighborhood Hits	171	Target Neighborhood Hits	437	Shared Neighborhood Hits	34
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

FUS_HUMAN
NC score	0.047011 (rank : 86)	θ value	0.47712 (rank : 60)
Query Neighborhood Hits	171	Target Neighborhood Hits	179	Shared Neighborhood Hits	22
SwissProt Accessions	P35637	Gene names	FUS, TLS
Domain Architecture
Description	RNA-binding protein FUS (Oncogene FUS) (Oncogene TLS) (Translocated in liposarcoma protein) (POMp75) (75 kDa DNA-pairing protein).

NFAT5_HUMAN
NC score	0.046753 (rank : 87)	θ value	0.47712 (rank : 62)
Query Neighborhood Hits	171	Target Neighborhood Hits	217	Shared Neighborhood Hits	26
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

ZIM10_HUMAN
NC score	0.045412 (rank : 88)	θ value	0.279714 (rank : 57)
Query Neighborhood Hits	171	Target Neighborhood Hits	577	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

MLL3_MOUSE
NC score	0.042138 (rank : 89)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	171	Target Neighborhood Hits	1399	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

TCF20_HUMAN
NC score	0.041869 (rank : 90)	θ value	1.38821 (rank : 85)
Query Neighborhood Hits	171	Target Neighborhood Hits	323	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

ZIM10_MOUSE
NC score	0.039918 (rank : 91)	θ value	0.62314 (rank : 70)
Query Neighborhood Hits	171	Target Neighborhood Hits	430	Shared Neighborhood Hits	34
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

GPS2_HUMAN
NC score	0.037597 (rank : 92)	θ value	3.0926 (rank : 101)
Query Neighborhood Hits	171	Target Neighborhood Hits	459	Shared Neighborhood Hits	32
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

TCF20_MOUSE
NC score	0.037302 (rank : 93)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	171	Target Neighborhood Hits	396	Shared Neighborhood Hits	41
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

HORN_MOUSE
NC score	0.036146 (rank : 94)	θ value	0.21417 (rank : 51)
Query Neighborhood Hits	171	Target Neighborhood Hits	218	Shared Neighborhood Hits	16
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

MN1_HUMAN
NC score	0.035920 (rank : 95)	θ value	2.36792 (rank : 97)
Query Neighborhood Hits	171	Target Neighborhood Hits	196	Shared Neighborhood Hits	20
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

BAZ2A_MOUSE
NC score	0.035474 (rank : 96)	θ value	0.813845 (rank : 71)
Query Neighborhood Hits	171	Target Neighborhood Hits	744	Shared Neighborhood Hits	37
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

N4BP2_HUMAN
NC score	0.033380 (rank : 97)	θ value	0.62314 (rank : 67)
Query Neighborhood Hits	171	Target Neighborhood Hits	107	Shared Neighborhood Hits	7
SwissProt Accessions	Q86UW6, Q9NVK2, Q9P2D4	Gene names	N4BP2, B3BP, KIAA1413
Domain Architecture
Description	NEDD4-binding protein 2 (EC 3.-.-.-) (N4BP2) (BCL-3-binding protein).

ATX2_MOUSE
NC score	0.032960 (rank : 98)	θ value	2.36792 (rank : 93)
Query Neighborhood Hits	171	Target Neighborhood Hits	445	Shared Neighborhood Hits	31
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

TCF7_MOUSE
NC score	0.032768 (rank : 99)	θ value	0.0736092 (rank : 44)
Query Neighborhood Hits	171	Target Neighborhood Hits	277	Shared Neighborhood Hits	18
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

NPBL_MOUSE
NC score	0.032019 (rank : 100)	θ value	0.62314 (rank : 69)
Query Neighborhood Hits	171	Target Neighborhood Hits	1041	Shared Neighborhood Hits	42
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NIPBL_HUMAN
NC score	0.031964 (rank : 101)	θ value	0.62314 (rank : 68)
Query Neighborhood Hits	171	Target Neighborhood Hits	1311	Shared Neighborhood Hits	48
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

RBBP6_MOUSE
NC score	0.031350 (rank : 102)	θ value	1.38821 (rank : 84)
Query Neighborhood Hits	171	Target Neighborhood Hits	1014	Shared Neighborhood Hits	28
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

HORN_HUMAN
NC score	0.030909 (rank : 103)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	171	Target Neighborhood Hits	206	Shared Neighborhood Hits	15
SwissProt Accessions	Q86YZ3	Gene names	HRNR, S100A18
Domain Architecture	No domain graphic available
Description	Hornerin.

RPTN_MOUSE
NC score	0.030130 (rank : 104)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	171	Target Neighborhood Hits	650	Shared Neighborhood Hits	46
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

K0240_HUMAN
NC score	0.029246 (rank : 105)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	171	Target Neighborhood Hits	96	Shared Neighborhood Hits	10
SwissProt Accessions	Q6AI39, Q5TFZ3, Q92514	Gene names	KIAA0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

MYST4_HUMAN
NC score	0.028485 (rank : 106)	θ value	0.813845 (rank : 72)
Query Neighborhood Hits	171	Target Neighborhood Hits	671	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

TREF1_MOUSE
NC score	0.028204 (rank : 107)	θ value	4.03905 (rank : 117)
Query Neighborhood Hits	171	Target Neighborhood Hits	682	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

RPTN_HUMAN
NC score	0.027466 (rank : 108)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	171	Target Neighborhood Hits	406	Shared Neighborhood Hits	27
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

TNR6A_HUMAN
NC score	0.027392 (rank : 109)	θ value	8.99809 (rank : 171)
Query Neighborhood Hits	171	Target Neighborhood Hits	343	Shared Neighborhood Hits	30
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

EMSY_HUMAN
NC score	0.027233 (rank : 110)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	171	Target Neighborhood Hits	296	Shared Neighborhood Hits	29
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

R3HD1_HUMAN
NC score	0.025806 (rank : 111)	θ value	6.88961 (rank : 144)
Query Neighborhood Hits	171	Target Neighborhood Hits	203	Shared Neighborhood Hits	23
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

LZTS2_MOUSE
NC score	0.025280 (rank : 112)	θ value	0.163984 (rank : 47)
Query Neighborhood Hits	171	Target Neighborhood Hits	423	Shared Neighborhood Hits	16
SwissProt Accessions	Q91YU6, Q569X6	Gene names	Lzts2, Kiaa1813
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2.

SNX15_MOUSE
NC score	0.024819 (rank : 113)	θ value	2.36792 (rank : 99)
Query Neighborhood Hits	171	Target Neighborhood Hits	62	Shared Neighborhood Hits	5
SwissProt Accessions	Q91WE1	Gene names	Snx15
Domain Architecture	No domain graphic available
Description	Sorting nexin-15.

MYST4_MOUSE
NC score	0.024470 (rank : 114)	θ value	1.38821 (rank : 82)
Query Neighborhood Hits	171	Target Neighborhood Hits	416	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

SFPQ_HUMAN
NC score	0.024392 (rank : 115)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	171	Target Neighborhood Hits	986	Shared Neighborhood Hits	49
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

ZF106_MOUSE
NC score	0.024253 (rank : 116)	θ value	4.03905 (rank : 120)
Query Neighborhood Hits	171	Target Neighborhood Hits	472	Shared Neighborhood Hits	21
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

PGCA_MOUSE
NC score	0.024046 (rank : 117)	θ value	0.47712 (rank : 63)
Query Neighborhood Hits	171	Target Neighborhood Hits	643	Shared Neighborhood Hits	26
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

GPTC8_HUMAN
NC score	0.023091 (rank : 118)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	171	Target Neighborhood Hits	366	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

INVO_HUMAN
NC score	0.022716 (rank : 119)	θ value	1.38821 (rank : 79)
Query Neighborhood Hits	171	Target Neighborhood Hits	636	Shared Neighborhood Hits	31
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

UBN1_HUMAN
NC score	0.020968 (rank : 120)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	171	Target Neighborhood Hits	170	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NPG3, Q13079, Q9P1P7	Gene names	UBN1
Domain Architecture	No domain graphic available
Description	Ubinuclein (Ubiquitously expressed nuclear protein) (VT4).

P73L_HUMAN
NC score	0.020743 (rank : 121)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	171	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H3D4, O75080, O75195, O75922, O76078, Q6VEG2, Q6VEG3, Q6VEG4, Q6VFJ1, Q6VFJ2, Q6VFJ3, Q6VH20, Q7LDI3, Q7LDI4, Q7LDI5, Q96KR0, Q9H3D2, Q9H3D3, Q9H3P8, Q9NPH7, Q9P1B4, Q9P1B5, Q9P1B6, Q9P1B7, Q9UBV9, Q9UE10, Q9UP26, Q9UP27, Q9UP28, Q9UP74	Gene names	TP73L, KET, P63, P73H, P73L
Domain Architecture	No domain graphic available
Description	Tumor protein p73-like (p73L) (p63) (Tumor protein 63) (TP63) (p51) (p40) (Keratinocyte transcription factor KET) (Chronic ulcerative stomatitis protein) (CUSP).

LIPS_HUMAN
NC score	0.020374 (rank : 122)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	171	Target Neighborhood Hits	314	Shared Neighborhood Hits	21
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

BBC3_HUMAN
NC score	0.020202 (rank : 123)	θ value	4.03905 (rank : 109)
Query Neighborhood Hits	171	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BXH1, O00171, Q96PG9	Gene names	BBC3, PUMA
Domain Architecture	No domain graphic available
Description	Bcl-2-binding component 3 (p53 up-regulated modulator of apoptosis) (JFY-1).

USBP1_MOUSE
NC score	0.019767 (rank : 124)	θ value	3.0926 (rank : 106)
Query Neighborhood Hits	171	Target Neighborhood Hits	115	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R370	Gene names	Ushbp1
Domain Architecture	No domain graphic available
Description	USH1C-binding protein 1 (Usher syndrome type-1C protein-binding protein 1).

ETV5_MOUSE
NC score	0.019265 (rank : 125)	θ value	0.21417 (rank : 50)
Query Neighborhood Hits	171	Target Neighborhood Hits	328	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

CNOT2_HUMAN
NC score	0.018783 (rank : 126)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	171	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NZN8, Q9H3E0, Q9NSX5, Q9NWR6, Q9P028	Gene names	CNOT2, CDC36, NOT2
Domain Architecture
Description	CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2).

CNOT2_MOUSE
NC score	0.018609 (rank : 127)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	171	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C5L3, Q3UE39, Q80YA5, Q9D0P1	Gene names	Cnot2
Domain Architecture
Description	CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2).

K0552_HUMAN
NC score	0.018295 (rank : 128)	θ value	4.03905 (rank : 113)
Query Neighborhood Hits	171	Target Neighborhood Hits	442	Shared Neighborhood Hits	14
SwissProt Accessions	O60299	Gene names	KIAA0552
Domain Architecture
Description	Protein KIAA0552.

FOXP4_MOUSE
NC score	0.017641 (rank : 129)	θ value	0.47712 (rank : 59)
Query Neighborhood Hits	171	Target Neighborhood Hits	211	Shared Neighborhood Hits	12
SwissProt Accessions	Q9DBY0, Q80V92, Q8CG10, Q8CIS1	Gene names	Foxp4
Domain Architecture	No domain graphic available
Description	Forkhead box protein P4 (Fork head-related protein like A) (mFKHLA).

LRC27_HUMAN
NC score	0.017404 (rank : 130)	θ value	0.47712 (rank : 61)
Query Neighborhood Hits	171	Target Neighborhood Hits	710	Shared Neighborhood Hits	18
SwissProt Accessions	Q9C0I9, Q5SZH6, Q5SZH8, Q5SZH9, Q86XT5, Q8N7C8, Q8NA21	Gene names	LRRC27, KIAA1674
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 27.

GAB2_HUMAN
NC score	0.017117 (rank : 131)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	171	Target Neighborhood Hits	188	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

GGA2_HUMAN
NC score	0.016609 (rank : 132)	θ value	4.03905 (rank : 111)
Query Neighborhood Hits	171	Target Neighborhood Hits	114	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UJY4, O14564, Q9NYN2, Q9UPS2	Gene names	GGA2, KIAA1080
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear).

FBX10_HUMAN
NC score	0.014885 (rank : 133)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	171	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UK96, Q5JRT8, Q9UKC3	Gene names	FBXO10, FBX10
Domain Architecture	No domain graphic available
Description	F-box only protein 10.

COIA1_MOUSE
NC score	0.013922 (rank : 134)	θ value	4.03905 (rank : 110)
Query Neighborhood Hits	171	Target Neighborhood Hits	481	Shared Neighborhood Hits	25
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

RUFY2_HUMAN
NC score	0.013659 (rank : 135)	θ value	1.81305 (rank : 90)
Query Neighborhood Hits	171	Target Neighborhood Hits	1208	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

INP5E_MOUSE
NC score	0.013545 (rank : 136)	θ value	2.36792 (rank : 96)
Query Neighborhood Hits	171	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JII1, Q3TCC9	Gene names	Inpp5e
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

TTLL4_MOUSE
NC score	0.012444 (rank : 137)	θ value	3.0926 (rank : 105)
Query Neighborhood Hits	171	Target Neighborhood Hits	103	Shared Neighborhood Hits	8
SwissProt Accessions	Q80UG8, Q5U4C4	Gene names	Ttll4, Kiaa0173
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 4.

EAN57_HUMAN
NC score	0.012431 (rank : 138)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	171	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	O43247, Q6ICF2, Q9Y4V8	Gene names	EAN57
Domain Architecture	No domain graphic available
Description	Protein EAN57.

HTF4_MOUSE
NC score	0.012378 (rank : 139)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	171	Target Neighborhood Hits	153	Shared Neighborhood Hits	14
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

ZCHC6_MOUSE
NC score	0.012367 (rank : 140)	θ value	3.0926 (rank : 108)
Query Neighborhood Hits	171	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	Q5BLK4, Q8CIH3	Gene names	Zcchc6
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 6.

TFE2_MOUSE
NC score	0.012285 (rank : 141)	θ value	5.27518 (rank : 134)
Query Neighborhood Hits	171	Target Neighborhood Hits	118	Shared Neighborhood Hits	8
SwissProt Accessions	P15806, Q3U153, Q8CAH9, Q8VCY4, Q922S2, Q99MB8, Q9CYJ4	Gene names	Tcf3, Alf2, Me2, Tcfe2a
Domain Architecture	No domain graphic available
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Transcription factor A1).

HDAC4_HUMAN
NC score	0.012038 (rank : 142)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	171	Target Neighborhood Hits	390	Shared Neighborhood Hits	21
SwissProt Accessions	P56524, Q9UND6	Gene names	HDAC4, KIAA0288
Domain Architecture
Description	Histone deacetylase 4 (HD4).

ALMS1_MOUSE
NC score	0.011913 (rank : 143)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	171	Target Neighborhood Hits	181	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K4E0, Q6A084, Q8C9N9	Gene names	Alms1, Kiaa0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1 homolog.

NOTC2_HUMAN
NC score	0.010482 (rank : 144)	θ value	0.365318 (rank : 58)
Query Neighborhood Hits	171	Target Neighborhood Hits	1113	Shared Neighborhood Hits	21
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NEST_HUMAN
NC score	0.009902 (rank : 145)	θ value	8.99809 (rank : 168)
Query Neighborhood Hits	171	Target Neighborhood Hits	1305	Shared Neighborhood Hits	34
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

APOA5_HUMAN
NC score	0.009879 (rank : 146)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	171	Target Neighborhood Hits	104	Shared Neighborhood Hits	5
SwissProt Accessions	Q6Q788, Q6UWK9, Q9UBJ3	Gene names	APOA5, RAP3
Domain Architecture	No domain graphic available
Description	Apolipoprotein A-V precursor (Apolipoprotein A5) (ApoAV) (ApoA-V) (Regeneration-associated protein 3).

NOTC2_MOUSE
NC score	0.009446 (rank : 147)	θ value	0.0961366 (rank : 46)
Query Neighborhood Hits	171	Target Neighborhood Hits	1069	Shared Neighborhood Hits	15
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

DC1L1_MOUSE
NC score	0.009234 (rank : 148)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	171	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R1Q8	Gene names	Dync1li1, Dncli1, Dnclic1
Domain Architecture	No domain graphic available
Description	Cytoplasmic dynein 1 light intermediate chain 1 (Dynein light intermediate chain 1, cytosolic) (Dynein light chain A) (DLC-A).

HIP1R_MOUSE
NC score	0.009220 (rank : 149)	θ value	4.03905 (rank : 112)
Query Neighborhood Hits	171	Target Neighborhood Hits	959	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

CO5A3_HUMAN
NC score	0.008731 (rank : 150)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	171	Target Neighborhood Hits	433	Shared Neighborhood Hits	21
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

ATAD2_HUMAN
NC score	0.008686 (rank : 151)	θ value	2.36792 (rank : 92)
Query Neighborhood Hits	171	Target Neighborhood Hits	322	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

SUHW4_MOUSE
NC score	0.008510 (rank : 152)	θ value	0.21417 (rank : 53)
Query Neighborhood Hits	171	Target Neighborhood Hits	737	Shared Neighborhood Hits	10
SwissProt Accessions	Q68FE8, Q3T9B1, Q8BI82	Gene names	Suhw4
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

FRM4A_HUMAN
NC score	0.008148 (rank : 153)	θ value	3.0926 (rank : 100)
Query Neighborhood Hits	171	Target Neighborhood Hits	110	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

ANDR_MOUSE
NC score	0.008034 (rank : 154)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	171	Target Neighborhood Hits	133	Shared Neighborhood Hits	8
SwissProt Accessions	P19091	Gene names	Ar, Nr3c4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

SOX10_HUMAN
NC score	0.007935 (rank : 155)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	171	Target Neighborhood Hits	122	Shared Neighborhood Hits	9
SwissProt Accessions	P56693	Gene names	SOX10
Domain Architecture
Description	Transcription factor SOX-10.

GO45_MOUSE
NC score	0.007754 (rank : 156)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	171	Target Neighborhood Hits	139	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R2X8, Q3TJC4, Q8C0U6, Q9DAV7	Gene names	Blzf1
Domain Architecture	No domain graphic available
Description	Golgin 45 (Basic leucine zipper nuclear factor 1).

FXR2_MOUSE
NC score	0.007704 (rank : 157)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	171	Target Neighborhood Hits	66	Shared Neighborhood Hits	9
SwissProt Accessions	Q9WVR4, Q9WVR5	Gene names	Fxr2, Fxr2h
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

SC6A5_MOUSE
NC score	0.007627 (rank : 158)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	171	Target Neighborhood Hits	135	Shared Neighborhood Hits	6
SwissProt Accessions	Q761V0, Q8CFM5, Q91ZQ2	Gene names	Slc6a5, Glyt2
Domain Architecture	No domain graphic available
Description	Sodium- and chloride-dependent glycine transporter 2 (GlyT2) (GlyT-2) (Solute carrier family 6 member 5).

NUCB1_HUMAN
NC score	0.007627 (rank : 159)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	171	Target Neighborhood Hits	359	Shared Neighborhood Hits	12
SwissProt Accessions	Q02818, Q15838, Q7Z4J7, Q9BUR1	Gene names	NUCB1, NUC
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

FOXN1_MOUSE
NC score	0.007541 (rank : 160)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	171	Target Neighborhood Hits	300	Shared Neighborhood Hits	22
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

ROCK2_MOUSE
NC score	0.007541 (rank : 161)	θ value	0.0252991 (rank : 40)
Query Neighborhood Hits	171	Target Neighborhood Hits	2072	Shared Neighborhood Hits	28
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

ABCBB_HUMAN
NC score	0.007416 (rank : 162)	θ value	2.36792 (rank : 91)
Query Neighborhood Hits	171	Target Neighborhood Hits	103	Shared Neighborhood Hits	4
SwissProt Accessions	O95342, Q9UNB2	Gene names	ABCB11, BSEP
Domain Architecture
Description	Bile salt export pump (ATP-binding cassette sub-family B member 11).

MRCKG_HUMAN
NC score	0.007137 (rank : 163)	θ value	0.0961366 (rank : 45)
Query Neighborhood Hits	171	Target Neighborhood Hits	1519	Shared Neighborhood Hits	22
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

LAMC2_MOUSE
NC score	0.007060 (rank : 164)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	171	Target Neighborhood Hits	614	Shared Neighborhood Hits	10
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

ROCK2_HUMAN
NC score	0.006732 (rank : 165)	θ value	0.163984 (rank : 49)
Query Neighborhood Hits	171	Target Neighborhood Hits	2073	Shared Neighborhood Hits	28
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

CO7A1_HUMAN
NC score	0.006530 (rank : 166)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	171	Target Neighborhood Hits	807	Shared Neighborhood Hits	25
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CSTF2_HUMAN
NC score	0.006456 (rank : 167)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	171	Target Neighborhood Hits	296	Shared Neighborhood Hits	13
SwissProt Accessions	P33240, Q5H951, Q6LA74, Q8N502	Gene names	CSTF2
Domain Architecture
Description	Cleavage stimulation factor 64 kDa subunit (CSTF 64 kDa subunit) (CF-1 64 kDa subunit) (CstF-64).

T3JAM_HUMAN
NC score	0.006367 (rank : 168)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	171	Target Neighborhood Hits	533	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

MDR3_MOUSE
NC score	0.006111 (rank : 169)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	171	Target Neighborhood Hits	106	Shared Neighborhood Hits	5
SwissProt Accessions	P21447	Gene names	Abcb1a, Abcb4, Mdr1a, Mdr3, Pgy-3, Pgy3
Domain Architecture
Description	Multidrug resistance protein 3 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1A) (P-glycoprotein 3) (MDR1A).

ZNFX1_MOUSE
NC score	0.005849 (rank : 170)	θ value	6.88961 (rank : 150)
Query Neighborhood Hits	171	Target Neighborhood Hits	407	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

WWP2_HUMAN
NC score	0.005798 (rank : 171)	θ value	4.03905 (rank : 119)
Query Neighborhood Hits	171	Target Neighborhood Hits	177	Shared Neighborhood Hits	10
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

PHLPP_HUMAN
NC score	0.005469 (rank : 172)	θ value	2.36792 (rank : 98)
Query Neighborhood Hits	171	Target Neighborhood Hits	604	Shared Neighborhood Hits	18
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

TAOK1_MOUSE
NC score	0.005367 (rank : 173)	θ value	0.279714 (rank : 56)
Query Neighborhood Hits	171	Target Neighborhood Hits	1720	Shared Neighborhood Hits	27
SwissProt Accessions	Q5F2E8, Q69ZL2, Q8JZX2, Q91VG7	Gene names	Taok1, Kiaa1361
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1).

ARHG9_MOUSE
NC score	0.005287 (rank : 174)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	171	Target Neighborhood Hits	234	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

MDR1_MOUSE
NC score	0.005279 (rank : 175)	θ value	8.99809 (rank : 166)
Query Neighborhood Hits	171	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	P06795	Gene names	Abcb1, Abcb1b, Mdr1, Mdr1b, Pgy1, Pgy1-1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).

ARHG9_HUMAN
NC score	0.005275 (rank : 176)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	171	Target Neighborhood Hits	235	Shared Neighborhood Hits	4
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

PCDA7_HUMAN
NC score	0.005096 (rank : 177)	θ value	1.81305 (rank : 88)
Query Neighborhood Hits	171	Target Neighborhood Hits	221	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UN72, O75282	Gene names	PCDHA7
Domain Architecture
Description	Protocadherin alpha 7 precursor (PCDH-alpha7).

TAOK1_HUMAN
NC score	0.005056 (rank : 178)	θ value	0.47712 (rank : 66)
Query Neighborhood Hits	171	Target Neighborhood Hits	1734	Shared Neighborhood Hits	28
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

ST1C1_MOUSE
NC score	0.004589 (rank : 179)	θ value	5.27518 (rank : 133)
Query Neighborhood Hits	171	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q80VR3, O70262	Gene names	Sult1c1, Sult1a2
Domain Architecture	No domain graphic available
Description	Sulfotransferase 1C1 (EC 2.8.2.-) (Phenol sulfotransferase).

ZBT46_MOUSE
NC score	0.004004 (rank : 180)	θ value	1.06291 (rank : 76)
Query Neighborhood Hits	171	Target Neighborhood Hits	813	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BID6, Q3U2R2, Q9D0G6, Q9D492	Gene names	Zbtb46, Btbd4
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 46 (BTB/POZ domain- containing protein 4).

ISL1_HUMAN
NC score	0.003634 (rank : 181)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	171	Target Neighborhood Hits	421	Shared Neighborhood Hits	5
SwissProt Accessions	P61371, P20663, P47894	Gene names	ISL1
Domain Architecture
Description	Insulin gene enhancer protein ISL-1 (Islet-1).

ISL1_MOUSE
NC score	0.003634 (rank : 182)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	171	Target Neighborhood Hits	421	Shared Neighborhood Hits	5
SwissProt Accessions	P61372, P20663, P47894, Q812D8	Gene names	Isl1
Domain Architecture
Description	Insulin gene enhancer protein ISL-1 (Islet-1).

PCDA5_HUMAN
NC score	0.003587 (rank : 183)	θ value	1.38821 (rank : 83)
Query Neighborhood Hits	171	Target Neighborhood Hits	217	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y5H7, O75284, Q8N4R3	Gene names	PCDHA5
Domain Architecture
Description	Protocadherin alpha 5 precursor (PCDH-alpha5).

AT2B2_HUMAN
NC score	0.003561 (rank : 184)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	171	Target Neighborhood Hits	75	Shared Neighborhood Hits	4
SwissProt Accessions	Q01814, O00766, Q12994, Q16818	Gene names	ATP2B2, PMCA2
Domain Architecture
Description	Plasma membrane calcium-transporting ATPase 2 (EC 3.6.3.8) (PMCA2) (Plasma membrane calcium pump isoform 2) (Plasma membrane calcium ATPase isoform 2).

AT2B2_MOUSE
NC score	0.003387 (rank : 185)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	171	Target Neighborhood Hits	68	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R0K7, O88863	Gene names	Atp2b2, Pmca2
Domain Architecture
Description	Plasma membrane calcium-transporting ATPase 2 (EC 3.6.3.8) (PMCA2) (Plasma membrane calcium pump isoform 2) (Plasma membrane calcium ATPase isoform 2).

STK10_MOUSE
NC score	0.003151 (rank : 186)	θ value	3.0926 (rank : 104)
Query Neighborhood Hits	171	Target Neighborhood Hits	2132	Shared Neighborhood Hits	47
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

BTBD9_MOUSE
NC score	0.002989 (rank : 187)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	171	Target Neighborhood Hits	165	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C726	Gene names	Btbd9
Domain Architecture
Description	BTB/POZ domain-containing protein 9.

NKX61_MOUSE
NC score	0.002787 (rank : 188)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	171	Target Neighborhood Hits	439	Shared Neighborhood Hits	12
SwissProt Accessions	Q99MA9, Q9ERQ7	Gene names	Nkx6-1, Nkx6.1, Nkx6a
Domain Architecture
Description	Homeobox protein Nkx-6.1.

MAST2_HUMAN
NC score	0.002049 (rank : 189)	θ value	8.99809 (rank : 165)
Query Neighborhood Hits	171	Target Neighborhood Hits	1189	Shared Neighborhood Hits	18
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

BMP2K_MOUSE
NC score	0.001785 (rank : 190)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	171	Target Neighborhood Hits	874	Shared Neighborhood Hits	17
SwissProt Accessions	Q91Z96, Q8C8L7	Gene names	Bmp2k, Bike
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

PRD16_HUMAN
NC score	0.000772 (rank : 191)	θ value	1.81305 (rank : 89)
Query Neighborhood Hits	171	Target Neighborhood Hits	832	Shared Neighborhood Hits	15
SwissProt Accessions	Q9HAZ2, Q8WYJ9, Q9C0I8	Gene names	PRDM16, KIAA1675, MEL1, PFM13
Domain Architecture
Description	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1).

ZBT46_HUMAN
NC score	0.000761 (rank : 192)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	171	Target Neighborhood Hits	813	Shared Neighborhood Hits	12
SwissProt Accessions	Q86UZ6, Q5JWJ3, Q9BQK3, Q9H3Z8, Q9H3Z9	Gene names	ZBTB46, BTBD4, ZNF340
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 46 (BTB/POZ domain- containing protein 4) (Zinc finger protein 340).

EVI1_HUMAN
NC score	0.000199 (rank : 193)	θ value	2.36792 (rank : 94)
Query Neighborhood Hits	171	Target Neighborhood Hits	924	Shared Neighborhood Hits	17
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.

KAISO_MOUSE
NC score	-0.000289 (rank : 194)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	171	Target Neighborhood Hits	821	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BN78, Q8C226, Q9WTZ7	Gene names	Zbtb33, Kaiso
Domain Architecture	No domain graphic available
Description	Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33).

WT1_MOUSE
NC score	-0.000537 (rank : 195)	θ value	3.0926 (rank : 107)
Query Neighborhood Hits	171	Target Neighborhood Hits	723	Shared Neighborhood Hits	12
SwissProt Accessions	P22561	Gene names	Wt1, Wt-1
Domain Architecture
Description	Wilms' tumor protein homolog.

WT1_HUMAN
NC score	-0.000704 (rank : 196)	θ value	4.03905 (rank : 118)
Query Neighborhood Hits	171	Target Neighborhood Hits	720	Shared Neighborhood Hits	12
SwissProt Accessions	P19544, Q15881, Q16256, Q16575, Q8IYZ5	Gene names	WT1
Domain Architecture
Description	Wilms' tumor protein (WT33).