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Network neighborhood for query Sequence : ANDR_MOUSE

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ANDR_MOUSE
SwissProt Accessions	P19091	Gene names	Ar, Nr3c4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ANDR_HUMAN
θ value	0 (rank : 1)	NC score	0.997021 (rank : 2)
Query Neighborhood Hits	133	Target Neighborhood Hits	126	Shared Neighborhood Hits	95
SwissProt Accessions	P10275	Gene names	AR, DHTR, NR3C4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

ANDR_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	133	Target Neighborhood Hits	133	Shared Neighborhood Hits	133
SwissProt Accessions	P19091	Gene names	Ar, Nr3c4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

PRGR_HUMAN
θ value	9.92011e-124 (rank : 3)	NC score	0.980031 (rank : 4)
Query Neighborhood Hits	133	Target Neighborhood Hits	163	Shared Neighborhood Hits	95
SwissProt Accessions	P06401, Q9UPF7	Gene names	PGR, NR3C3
Domain Architecture
Description	Progesterone receptor (PR).

PRGR_MOUSE
θ value	3.76964e-123 (rank : 4)	NC score	0.973357 (rank : 8)
Query Neighborhood Hits	133	Target Neighborhood Hits	286	Shared Neighborhood Hits	99
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

MCR_HUMAN
θ value	6.24247e-110 (rank : 5)	NC score	0.976063 (rank : 6)
Query Neighborhood Hits	133	Target Neighborhood Hits	149	Shared Neighborhood Hits	97
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

GCR_HUMAN
θ value	1.17728e-108 (rank : 6)	NC score	0.980879 (rank : 3)
Query Neighborhood Hits	133	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P04150, P04151, Q53EP5, Q6N0A4	Gene names	NR3C1, GRL
Domain Architecture
Description	Glucocorticoid receptor (GR).

MCR_MOUSE
θ value	2.6227e-108 (rank : 7)	NC score	0.974448 (rank : 7)
Query Neighborhood Hits	133	Target Neighborhood Hits	162	Shared Neighborhood Hits	97
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

GCR_MOUSE
θ value	7.14227e-106 (rank : 8)	NC score	0.979958 (rank : 5)
Query Neighborhood Hits	133	Target Neighborhood Hits	117	Shared Neighborhood Hits	94
SwissProt Accessions	P06537, Q61628, Q61629	Gene names	Nr3c1, Grl, Grl1
Domain Architecture
Description	Glucocorticoid receptor (GR).

ESR1_MOUSE
θ value	1.16164e-39 (rank : 9)	NC score	0.935814 (rank : 9)
Query Neighborhood Hits	133	Target Neighborhood Hits	104	Shared Neighborhood Hits	94
SwissProt Accessions	P19785, Q9JJT5, Q9QY51, Q9QY52	Gene names	Esr1, Esr, Estr, Estra, Nr3a1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

ESR1_HUMAN
θ value	1.98146e-39 (rank : 10)	NC score	0.934687 (rank : 12)
Query Neighborhood Hits	133	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P03372, Q13511, Q14276, Q9NU51, Q9UDZ7, Q9UIS7	Gene names	ESR1, ESR, NR3A1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

ESR2_MOUSE
θ value	4.41421e-39 (rank : 11)	NC score	0.935020 (rank : 10)
Query Neighborhood Hits	133	Target Neighborhood Hits	110	Shared Neighborhood Hits	94
SwissProt Accessions	O08537, O35635, O70519	Gene names	Esr2, Estrb, Nr3a2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

ESR2_HUMAN
θ value	1.6774e-38 (rank : 12)	NC score	0.934985 (rank : 11)
Query Neighborhood Hits	133	Target Neighborhood Hits	110	Shared Neighborhood Hits	94
SwissProt Accessions	Q92731, O60608, O60685, O60702, O60703, O75583, O75584, Q86Z31, Q9UEV6, Q9UHD3, Q9UQK9	Gene names	ESR2, ESTRB, NR3A2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

ERR3_HUMAN
θ value	5.96599e-36 (rank : 13)	NC score	0.924220 (rank : 16)
Query Neighborhood Hits	133	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	P62508, O75454, O96021, Q68DA0, Q6P274, Q6PK28, Q6TS38, Q9R1F3, Q9UNJ4	Gene names	ESRRG, ERR3, ERRG2, KIAA0832, NR3B3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (ERR gamma-2).

ERR3_MOUSE
θ value	5.96599e-36 (rank : 14)	NC score	0.924220 (rank : 17)
Query Neighborhood Hits	133	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	P62509, O75454, O96021, Q8CHC9, Q9R1F3	Gene names	Esrrg, Err3, Kiaa0832, Nr3b3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3).

ERR2_MOUSE
θ value	5.0505e-35 (rank : 15)	NC score	0.926330 (rank : 15)
Query Neighborhood Hits	133	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	Q61539, O09067, O09146	Gene names	Esrrb, Err-2, Err2, Nr3b2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2).

ERR2_HUMAN
θ value	6.59618e-35 (rank : 16)	NC score	0.926470 (rank : 14)
Query Neighborhood Hits	133	Target Neighborhood Hits	108	Shared Neighborhood Hits	94
SwissProt Accessions	O95718, Q9HCB4	Gene names	ESRRB, ERRB2, NR3B2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2) (ERR beta-2).

ERR1_HUMAN
θ value	1.46948e-34 (rank : 17)	NC score	0.928777 (rank : 13)
Query Neighborhood Hits	133	Target Neighborhood Hits	157	Shared Neighborhood Hits	94
SwissProt Accessions	P11474, Q14514	Gene names	ESRRA, ERR1, ESRL1, NR3B1
Domain Architecture
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR- alpha) (Estrogen receptor-like 1).

RXRB_HUMAN
θ value	2.27234e-27 (rank : 18)	NC score	0.880106 (rank : 37)
Query Neighborhood Hits	133	Target Neighborhood Hits	280	Shared Neighborhood Hits	101
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

RXRB_MOUSE
θ value	1.92365e-26 (rank : 19)	NC score	0.883179 (rank : 32)
Query Neighborhood Hits	133	Target Neighborhood Hits	230	Shared Neighborhood Hits	102
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

RXRA_HUMAN
θ value	5.59698e-26 (rank : 20)	NC score	0.883451 (rank : 31)
Query Neighborhood Hits	133	Target Neighborhood Hits	223	Shared Neighborhood Hits	95
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

RXRA_MOUSE
θ value	7.30988e-26 (rank : 21)	NC score	0.886162 (rank : 24)
Query Neighborhood Hits	133	Target Neighborhood Hits	129	Shared Neighborhood Hits	94
SwissProt Accessions	P28700	Gene names	Rxra, Nr2b1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

RXRG_HUMAN
θ value	7.30988e-26 (rank : 22)	NC score	0.884926 (rank : 26)
Query Neighborhood Hits	133	Target Neighborhood Hits	114	Shared Neighborhood Hits	94
SwissProt Accessions	P48443	Gene names	RXRG, NR2B3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

EAR2_HUMAN
θ value	2.77775e-25 (rank : 23)	NC score	0.884188 (rank : 27)
Query Neighborhood Hits	133	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	P10588, Q9BUE8	Gene names	NR2F6, EAR2, ERBAL2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

RXRG_MOUSE
θ value	2.77775e-25 (rank : 24)	NC score	0.886217 (rank : 23)
Query Neighborhood Hits	133	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P28705	Gene names	Rxrg, Nr2b3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

HNF4G_HUMAN
θ value	4.01107e-24 (rank : 25)	NC score	0.888825 (rank : 21)
Query Neighborhood Hits	133	Target Neighborhood Hits	100	Shared Neighborhood Hits	94
SwissProt Accessions	Q14541, Q9UH81, Q9UIS6	Gene names	HNF4G, NR2A2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

HNF4G_MOUSE
θ value	6.84181e-24 (rank : 26)	NC score	0.888034 (rank : 22)
Query Neighborhood Hits	133	Target Neighborhood Hits	101	Shared Neighborhood Hits	94
SwissProt Accessions	Q9WUU6	Gene names	Hnf4g, Nr2a2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

COT2_HUMAN
θ value	8.93572e-24 (rank : 27)	NC score	0.879705 (rank : 39)
Query Neighborhood Hits	133	Target Neighborhood Hits	135	Shared Neighborhood Hits	94
SwissProt Accessions	P24468, Q03754	Gene names	NR2F2, ARP1, TFCOUP2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

COT2_MOUSE
θ value	8.93572e-24 (rank : 28)	NC score	0.879705 (rank : 40)
Query Neighborhood Hits	133	Target Neighborhood Hits	135	Shared Neighborhood Hits	94
SwissProt Accessions	P43135	Gene names	Nr2f2, Aporp1, Arp-1, Arp1, Tfcoup2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

COT1_HUMAN
θ value	7.56453e-23 (rank : 29)	NC score	0.877576 (rank : 45)
Query Neighborhood Hits	133	Target Neighborhood Hits	159	Shared Neighborhood Hits	94
SwissProt Accessions	P10589	Gene names	NR2F1, EAR3, ERBAL3, TFCOUP1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I) (V-ERBA-related protein EAR-3).

COT1_MOUSE
θ value	7.56453e-23 (rank : 30)	NC score	0.877868 (rank : 44)
Query Neighborhood Hits	133	Target Neighborhood Hits	160	Shared Neighborhood Hits	94
SwissProt Accessions	Q60632, Q61438	Gene names	Nr2f1, Erbal3, Tfcoup1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I).

EAR2_MOUSE
θ value	7.56453e-23 (rank : 31)	NC score	0.883478 (rank : 30)
Query Neighborhood Hits	133	Target Neighborhood Hits	104	Shared Neighborhood Hits	94
SwissProt Accessions	P43136, Q61504	Gene names	Nr2f6, Ear-2, Ear2, Erbal2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

NR1H3_MOUSE
θ value	1.29031e-22 (rank : 32)	NC score	0.876936 (rank : 48)
Query Neighborhood Hits	133	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Z0Y9, Q9QUH7	Gene names	Nr1h3, Lxra
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

NR1H3_HUMAN
θ value	1.6852e-22 (rank : 33)	NC score	0.877022 (rank : 47)
Query Neighborhood Hits	133	Target Neighborhood Hits	104	Shared Neighborhood Hits	94
SwissProt Accessions	Q13133, Q96H87	Gene names	NR1H3, LXRA
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

NR2E1_MOUSE
θ value	2.20094e-22 (rank : 34)	NC score	0.895198 (rank : 18)
Query Neighborhood Hits	133	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	Q64104	Gene names	Nr2e1, Tll, Tlx
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (mTll).

HNF4A_MOUSE
θ value	4.9032e-22 (rank : 35)	NC score	0.885593 (rank : 25)
Query Neighborhood Hits	133	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	P49698	Gene names	Hnf4a, Hnf-4, Hnf4, Nr2a1, Tcf14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

NR2E3_MOUSE
θ value	4.9032e-22 (rank : 36)	NC score	0.891139 (rank : 20)
Query Neighborhood Hits	133	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	Q9QXZ7	Gene names	Nr2e3, Pnr, Rnr
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

NR2E1_HUMAN
θ value	6.40375e-22 (rank : 37)	NC score	0.892001 (rank : 19)
Query Neighborhood Hits	133	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y466	Gene names	NR2E1, TLX
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (hTll).

NR2E3_HUMAN
θ value	6.40375e-22 (rank : 38)	NC score	0.883794 (rank : 29)
Query Neighborhood Hits	133	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y5X4, Q9UHM4	Gene names	NR2E3, PNR, RNR
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

NR4A1_HUMAN
θ value	1.42661e-21 (rank : 39)	NC score	0.881735 (rank : 33)
Query Neighborhood Hits	133	Target Neighborhood Hits	133	Shared Neighborhood Hits	95
SwissProt Accessions	P22736	Gene names	NR4A1, GFRP1, HMR, NAK1
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Early response protein NAK1) (TR3 orphan receptor) (ST-59).

NR4A3_HUMAN
θ value	1.42661e-21 (rank : 40)	NC score	0.881681 (rank : 34)
Query Neighborhood Hits	133	Target Neighborhood Hits	131	Shared Neighborhood Hits	97
SwissProt Accessions	Q92570, Q12935, Q14979, Q16420, Q4VXA9, Q9UEK2, Q9UEK3	Gene names	NR4A3, CHN, CSMF, MINOR, NOR1, TEC
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Nuclear hormone receptor NOR-1) (Neuron-derived orphan receptor 1) (Mitogen-induced nuclear orphan receptor).

NR4A3_MOUSE
θ value	1.42661e-21 (rank : 41)	NC score	0.880808 (rank : 35)
Query Neighborhood Hits	133	Target Neighborhood Hits	127	Shared Neighborhood Hits	96
SwissProt Accessions	Q9QZB6, Q9QZB5	Gene names	Nr4a3, Tec
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Orphan nuclear receptor TEC) (Translocated in extraskeletal chondrosarcoma).

NR4A2_HUMAN
θ value	4.15078e-21 (rank : 42)	NC score	0.879756 (rank : 38)
Query Neighborhood Hits	133	Target Neighborhood Hits	120	Shared Neighborhood Hits	96
SwissProt Accessions	P43354, Q16311	Gene names	NR4A2, NOT, NURR1, TINUR
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (Immediate-early response protein NOT) (Transcriptionally-inducible nuclear receptor).

NR4A2_MOUSE
θ value	4.15078e-21 (rank : 43)	NC score	0.879642 (rank : 41)
Query Neighborhood Hits	133	Target Neighborhood Hits	121	Shared Neighborhood Hits	96
SwissProt Accessions	Q06219, O08690	Gene names	Nr4a2, Nurr1
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (NUR- related factor 1).

RARG1_HUMAN
θ value	4.15078e-21 (rank : 44)	NC score	0.871672 (rank : 54)
Query Neighborhood Hits	133	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	P13631	Gene names	RARG, NR1B3
Domain Architecture
Description	Retinoic acid receptor gamma-1 (RAR-gamma-1).

RARG1_MOUSE
θ value	4.15078e-21 (rank : 45)	NC score	0.871244 (rank : 56)
Query Neighborhood Hits	133	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

RARG2_HUMAN
θ value	4.15078e-21 (rank : 46)	NC score	0.871690 (rank : 53)
Query Neighborhood Hits	133	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	P22932, Q15281	Gene names	RARG, NR1B3
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor gamma-2 (RAR-gamma-2).

RARG2_MOUSE
θ value	4.15078e-21 (rank : 47)	NC score	0.871469 (rank : 55)
Query Neighborhood Hits	133	Target Neighborhood Hits	114	Shared Neighborhood Hits	94
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

HNF4A_HUMAN
θ value	7.0802e-21 (rank : 48)	NC score	0.883953 (rank : 28)
Query Neighborhood Hits	133	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P41235, O00659, O00723, Q14540, Q92653, Q92654, Q92655, Q99864, Q9NQH0	Gene names	HNF4A, HNF4, NR2A1, TCF14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

NR4A1_MOUSE
θ value	9.24701e-21 (rank : 49)	NC score	0.880789 (rank : 36)
Query Neighborhood Hits	133	Target Neighborhood Hits	128	Shared Neighborhood Hits	94
SwissProt Accessions	P12813	Gene names	Nr4a1, Gfrp, Hmr, N10, Nur77
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Nuclear hormone receptor NUR/77) (N10 nuclear protein).

RARB_HUMAN
θ value	9.24701e-21 (rank : 50)	NC score	0.868311 (rank : 60)
Query Neighborhood Hits	133	Target Neighborhood Hits	118	Shared Neighborhood Hits	94
SwissProt Accessions	P10826, P12891, Q00989, Q15298, Q9UN48	Gene names	RARB, HAP, NR1B2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta) (RAR-epsilon) (HBV-activated protein).

NR1H2_MOUSE
θ value	1.2077e-20 (rank : 51)	NC score	0.867293 (rank : 63)
Query Neighborhood Hits	133	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	Q60644	Gene names	Nr1h2, Lxrb, Rip15, Unr, Unr2
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Retinoid X receptor-interacting protein No.15).

NR1H4_HUMAN
θ value	1.2077e-20 (rank : 52)	NC score	0.879429 (rank : 42)
Query Neighborhood Hits	133	Target Neighborhood Hits	112	Shared Neighborhood Hits	95
SwissProt Accessions	Q96RI1, Q8NFP5, Q8NFP6, Q92943	Gene names	NR1H4, BAR, FXR, HRR1, RIP14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

NR1H2_HUMAN
θ value	1.5773e-20 (rank : 53)	NC score	0.862581 (rank : 65)
Query Neighborhood Hits	133	Target Neighborhood Hits	114	Shared Neighborhood Hits	94
SwissProt Accessions	P55055, Q12970	Gene names	NR1H2, LXRB, NER, UNR
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Nuclear receptor NER).

RARB_MOUSE
θ value	1.5773e-20 (rank : 54)	NC score	0.868106 (rank : 62)
Query Neighborhood Hits	133	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	P22605, P11417, P22604	Gene names	Rarb, Nr1b2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta).

RARA_HUMAN
θ value	2.06002e-20 (rank : 55)	NC score	0.868565 (rank : 59)
Query Neighborhood Hits	133	Target Neighborhood Hits	118	Shared Neighborhood Hits	94
SwissProt Accessions	P10276, P78456, Q13440, Q13441, Q9NQS0	Gene names	RARA, NR1B1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARA_MOUSE
θ value	2.69047e-20 (rank : 56)	NC score	0.868168 (rank : 61)
Query Neighborhood Hits	133	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P11416, P22603	Gene names	Rara, Nr1b1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

NR1H4_MOUSE
θ value	4.58923e-20 (rank : 57)	NC score	0.877513 (rank : 46)
Query Neighborhood Hits	133	Target Neighborhood Hits	113	Shared Neighborhood Hits	95
SwissProt Accessions	Q60641, Q60642, Q60643	Gene names	Nr1h4, Bar, Fxr, Rip14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

NR1I3_MOUSE
θ value	5.99374e-20 (rank : 58)	NC score	0.878487 (rank : 43)
Query Neighborhood Hits	133	Target Neighborhood Hits	103	Shared Neighborhood Hits	95
SwissProt Accessions	O35627, O35628	Gene names	Nr1i3, Car
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Orphan nuclear receptor MB67).

NR5A2_MOUSE
θ value	8.65492e-19 (rank : 59)	NC score	0.869704 (rank : 58)
Query Neighborhood Hits	133	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	P45448	Gene names	Nr5a2, Lrh1
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Liver receptor homolog 1) (LRH-1).

NR5A2_HUMAN
θ value	2.5182e-18 (rank : 60)	NC score	0.866292 (rank : 64)
Query Neighborhood Hits	133	Target Neighborhood Hits	112	Shared Neighborhood Hits	94
SwissProt Accessions	O00482, O95642	Gene names	NR5A2, B1F, CPF, FTF
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Alpha-1-fetoprotein transcription factor) (Hepatocytic transcription factor) (B1-binding factor) (hB1F) (CYP7A promoter-binding factor) (Liver receptor homolog 1) (LRH-1).

NR1I3_HUMAN
θ value	1.63225e-17 (rank : 61)	NC score	0.875923 (rank : 49)
Query Neighborhood Hits	133	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	Q14994	Gene names	NR1I3, CAR
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Constitutive activator of retinoid response) (Constitutive active response) (Orphan nuclear receptor MB67).

STF1_HUMAN
θ value	1.63225e-17 (rank : 62)	NC score	0.874964 (rank : 50)
Query Neighborhood Hits	133	Target Neighborhood Hits	132	Shared Neighborhood Hits	94
SwissProt Accessions	Q13285, O15196	Gene names	NR5A1, AD4BP, FTZF1, SF1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1).

STF1_MOUSE
θ value	1.63225e-17 (rank : 63)	NC score	0.874216 (rank : 51)
Query Neighborhood Hits	133	Target Neighborhood Hits	137	Shared Neighborhood Hits	95
SwissProt Accessions	P33242	Gene names	Nr5a1, Ftzf1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1) (Embryonal LTR-binding protein) (ELP) (Embryonal long terminal repeat- binding protein) (Steroid hydroxylase positive regulator).

TR4_HUMAN
θ value	1.80466e-16 (rank : 64)	NC score	0.847225 (rank : 72)
Query Neighborhood Hits	133	Target Neighborhood Hits	117	Shared Neighborhood Hits	94
SwissProt Accessions	P49116, P55092	Gene names	NR2C2, TAK1, TR4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

TR4_MOUSE
θ value	2.35696e-16 (rank : 65)	NC score	0.846865 (rank : 73)
Query Neighborhood Hits	133	Target Neighborhood Hits	115	Shared Neighborhood Hits	94
SwissProt Accessions	P49117, P55093	Gene names	Nr2c2, Mtr2r1, Tak1, Tr4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

RORA_HUMAN
θ value	8.95645e-16 (rank : 66)	NC score	0.845119 (rank : 79)
Query Neighborhood Hits	133	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P35398, P35397, P35399, P45445, Q96H83	Gene names	RORA, NR1F1, RZRA
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

NR6A1_HUMAN
θ value	1.52774e-15 (rank : 67)	NC score	0.871921 (rank : 52)
Query Neighborhood Hits	133	Target Neighborhood Hits	108	Shared Neighborhood Hits	94
SwissProt Accessions	Q15406, O00551, O00603, Q8NHQ0, Q92898, Q99802	Gene names	NR6A1, GCNF
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

NR6A1_MOUSE
θ value	1.52774e-15 (rank : 68)	NC score	0.870514 (rank : 57)
Query Neighborhood Hits	133	Target Neighborhood Hits	110	Shared Neighborhood Hits	94
SwissProt Accessions	Q64249	Gene names	Nr6a1, Gcnf
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

RORB_HUMAN
θ value	1.99529e-15 (rank : 69)	NC score	0.845238 (rank : 78)
Query Neighborhood Hits	133	Target Neighborhood Hits	99	Shared Neighborhood Hits	94
SwissProt Accessions	Q92753, Q8WX73	Gene names	RORB, NR1F2, RZRB
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

RORB_MOUSE
θ value	1.99529e-15 (rank : 70)	NC score	0.845403 (rank : 77)
Query Neighborhood Hits	133	Target Neighborhood Hits	99	Shared Neighborhood Hits	94
SwissProt Accessions	Q8R1B8	Gene names	Rorb, Nr1f2
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

RORA_MOUSE
θ value	2.60593e-15 (rank : 71)	NC score	0.843650 (rank : 81)
Query Neighborhood Hits	133	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P51448, P70283, P97741, P97773, Q923G1	Gene names	Rora, Nr1f1, Rzra
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

THB2_HUMAN
θ value	3.40345e-15 (rank : 72)	NC score	0.838790 (rank : 84)
Query Neighborhood Hits	133	Target Neighborhood Hits	104	Shared Neighborhood Hits	95
SwissProt Accessions	P37243	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor beta-2.

RORG_MOUSE
θ value	5.8054e-15 (rank : 73)	NC score	0.844738 (rank : 80)
Query Neighborhood Hits	133	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	P51450, Q61027, Q91YT5, Q9QXD9, Q9R177	Gene names	Rorc, Nr1f3, Rorg, Thor
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma) (Thymus orphan receptor) (TOR).

TR2_MOUSE
θ value	5.8054e-15 (rank : 74)	NC score	0.849250 (rank : 69)
Query Neighborhood Hits	133	Target Neighborhood Hits	100	Shared Neighborhood Hits	94
SwissProt Accessions	Q505F1, P97763, Q3UIJ7, Q4U1Z4, Q60927, Q62152, Q8VIJ3	Gene names	Nr2c1, Tr2, Tr2-11
Domain Architecture	No domain graphic available
Description	Orphan nuclear receptor TR2 (Testicular receptor 2) (mTR2).

VDR_MOUSE
θ value	7.58209e-15 (rank : 75)	NC score	0.849931 (rank : 68)
Query Neighborhood Hits	133	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	P48281	Gene names	Vdr, Nr1i1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

RORG_HUMAN
θ value	9.90251e-15 (rank : 76)	NC score	0.839564 (rank : 82)
Query Neighborhood Hits	133	Target Neighborhood Hits	119	Shared Neighborhood Hits	94
SwissProt Accessions	P51449, Q8N5V7, Q8NCY8	Gene names	RORC, NR1F3, RORG, RZRG
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma).

TR2_HUMAN
θ value	9.90251e-15 (rank : 77)	NC score	0.862542 (rank : 66)
Query Neighborhood Hits	133	Target Neighborhood Hits	110	Shared Neighborhood Hits	94
SwissProt Accessions	P13056	Gene names	NR2C1, TR2
Domain Architecture
Description	Orphan nuclear receptor TR2 (Testicular receptor 2).

VDR_HUMAN
θ value	9.90251e-15 (rank : 78)	NC score	0.848463 (rank : 70)
Query Neighborhood Hits	133	Target Neighborhood Hits	112	Shared Neighborhood Hits	94
SwissProt Accessions	P11473	Gene names	VDR, NR1I1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

THB1_HUMAN
θ value	1.29331e-14 (rank : 79)	NC score	0.836138 (rank : 87)
Query Neighborhood Hits	133	Target Neighborhood Hits	106	Shared Neighborhood Hits	95
SwissProt Accessions	P10828, Q13986	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture
Description	Thyroid hormone receptor beta-1.

THB1_MOUSE
θ value	1.68911e-14 (rank : 80)	NC score	0.835823 (rank : 88)
Query Neighborhood Hits	133	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P37242	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-1.

THB2_MOUSE
θ value	1.68911e-14 (rank : 81)	NC score	0.836276 (rank : 86)
Query Neighborhood Hits	133	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	P37244	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-2.

THA_HUMAN
θ value	1.42992e-13 (rank : 82)	NC score	0.846828 (rank : 74)
Query Neighborhood Hits	133	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P10827, P21205, Q8N6A1, Q96H73	Gene names	THRA, ERBA1, NR1A1, THRA1
Domain Architecture
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1) (EAR-7) (EAR7).

PPARA_HUMAN
θ value	1.86753e-13 (rank : 83)	NC score	0.835566 (rank : 89)
Query Neighborhood Hits	133	Target Neighborhood Hits	100	Shared Neighborhood Hits	94
SwissProt Accessions	Q07869, Q16241, Q92486, Q92689, Q9Y3N1	Gene names	PPARA, NR1C1, PPAR
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

PXR_MOUSE
θ value	1.86753e-13 (rank : 84)	NC score	0.851031 (rank : 67)
Query Neighborhood Hits	133	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	O54915	Gene names	Nr1i2, Pxr
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor).

THA_MOUSE
θ value	1.86753e-13 (rank : 85)	NC score	0.846494 (rank : 75)
Query Neighborhood Hits	133	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P63058, P10685, P15827, P16416, P37241, Q63107, Q63195, Q63196, Q99146	Gene names	Thra, C-erba-alpha, Nr1a1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1).

PPARA_MOUSE
θ value	5.43371e-13 (rank : 86)	NC score	0.834447 (rank : 90)
Query Neighborhood Hits	133	Target Neighborhood Hits	99	Shared Neighborhood Hits	94
SwissProt Accessions	P23204	Gene names	Ppara, Nr1c1, Ppar
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

PXR_HUMAN
θ value	3.52202e-12 (rank : 87)	NC score	0.845890 (rank : 76)
Query Neighborhood Hits	133	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	O75469, Q96AC7, Q9UJ22, Q9UJ23, Q9UJ24, Q9UJ25, Q9UJ26, Q9UJ27	Gene names	NR1I2, PXR
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor) (Orphan nuclear receptor PAR1) (Steroid and xenobiotic receptor) (SXR).

PPARG_HUMAN
θ value	4.59992e-12 (rank : 88)	NC score	0.831280 (rank : 91)
Query Neighborhood Hits	133	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37231, O00684, O00710, O14515, Q15178, Q15179, Q15180, Q15832, Q86U60, Q96J12	Gene names	PPARG, NR1C3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

PPARD_HUMAN
θ value	1.33837e-11 (rank : 89)	NC score	0.827616 (rank : 93)
Query Neighborhood Hits	133	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q03181, Q7Z5K0, Q9BUD4	Gene names	PPARD, NR1C2, PPARB
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1) (NUCI).

PPARG_MOUSE
θ value	1.33837e-11 (rank : 90)	NC score	0.830024 (rank : 92)
Query Neighborhood Hits	133	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37238	Gene names	Pparg, Nr1c3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

NR1D1_HUMAN
θ value	2.28291e-11 (rank : 91)	NC score	0.847568 (rank : 71)
Query Neighborhood Hits	133	Target Neighborhood Hits	140	Shared Neighborhood Hits	96
SwissProt Accessions	P20393, Q15304	Gene names	NR1D1, EAR1, HREV, THRAL
Domain Architecture
Description	Orphan nuclear receptor NR1D1 (V-erbA-related protein EAR-1) (Rev- erbA-alpha).

NR1D2_HUMAN
θ value	2.28291e-11 (rank : 92)	NC score	0.839038 (rank : 83)
Query Neighborhood Hits	133	Target Neighborhood Hits	115	Shared Neighborhood Hits	94
SwissProt Accessions	Q14995, O00402, Q86XD4	Gene names	NR1D2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (EAR-1R) (Orphan nuclear hormone receptor BD73).

NR1D2_MOUSE
θ value	2.28291e-11 (rank : 93)	NC score	0.836604 (rank : 85)
Query Neighborhood Hits	133	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	Q60674, Q60646	Gene names	Nr1d2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (Orphan nuclear receptor RVR).

PPARD_MOUSE
θ value	3.89403e-11 (rank : 94)	NC score	0.824577 (rank : 94)
Query Neighborhood Hits	133	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	P35396, P37239	Gene names	Ppard, Nr1c2, Pparb
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1).

MA1B1_HUMAN
θ value	0.0113563 (rank : 95)	NC score	0.022192 (rank : 101)
Query Neighborhood Hits	133	Target Neighborhood Hits	125	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UKM7, Q5VSG3, Q9BRS9, Q9Y5K7	Gene names	MAN1B1
Domain Architecture
Description	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific-processing alpha-mannosidase).

BAT2_HUMAN
θ value	0.0961366 (rank : 96)	NC score	0.029786 (rank : 99)
Query Neighborhood Hits	133	Target Neighborhood Hits	931	Shared Neighborhood Hits	20
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAT2_MOUSE
θ value	0.163984 (rank : 97)	NC score	0.026561 (rank : 100)
Query Neighborhood Hits	133	Target Neighborhood Hits	947	Shared Neighborhood Hits	18
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

GLI3_HUMAN
θ value	0.163984 (rank : 98)	NC score	-0.000267 (rank : 126)
Query Neighborhood Hits	133	Target Neighborhood Hits	871	Shared Neighborhood Hits	10
SwissProt Accessions	P10071, O75219, Q9UDT5, Q9UJ39	Gene names	GLI3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.

GLI3_MOUSE
θ value	0.47712 (rank : 99)	NC score	-0.000785 (rank : 128)
Query Neighborhood Hits	133	Target Neighborhood Hits	807	Shared Neighborhood Hits	8
SwissProt Accessions	Q61602	Gene names	Gli3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.

RGS3_MOUSE
θ value	0.47712 (rank : 100)	NC score	0.009204 (rank : 109)
Query Neighborhood Hits	133	Target Neighborhood Hits	1621	Shared Neighborhood Hits	23
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

GLI2_HUMAN
θ value	0.62314 (rank : 101)	NC score	-0.000003 (rank : 125)
Query Neighborhood Hits	133	Target Neighborhood Hits	971	Shared Neighborhood Hits	17
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

ALO17_HUMAN
θ value	0.813845 (rank : 102)	NC score	0.015771 (rank : 104)
Query Neighborhood Hits	133	Target Neighborhood Hits	317	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

NCOA2_HUMAN
θ value	1.06291 (rank : 103)	NC score	0.015753 (rank : 105)
Query Neighborhood Hits	133	Target Neighborhood Hits	281	Shared Neighborhood Hits	12
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

EPHA1_HUMAN
θ value	1.38821 (rank : 104)	NC score	-0.006407 (rank : 135)
Query Neighborhood Hits	133	Target Neighborhood Hits	997	Shared Neighborhood Hits	4
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

LBX1_HUMAN
θ value	1.38821 (rank : 105)	NC score	-0.000701 (rank : 127)
Query Neighborhood Hits	133	Target Neighborhood Hits	357	Shared Neighborhood Hits	2
SwissProt Accessions	P52954	Gene names	LBX1
Domain Architecture
Description	Transcription factor LBX1.

PAK4_MOUSE
θ value	1.38821 (rank : 106)	NC score	-0.007377 (rank : 136)
Query Neighborhood Hits	133	Target Neighborhood Hits	1098	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

GOGB1_HUMAN
θ value	1.81305 (rank : 107)	NC score	-0.008480 (rank : 137)
Query Neighborhood Hits	133	Target Neighborhood Hits	2297	Shared Neighborhood Hits	7
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

NCOA2_MOUSE
θ value	2.36792 (rank : 108)	NC score	0.011458 (rank : 108)
Query Neighborhood Hits	133	Target Neighborhood Hits	281	Shared Neighborhood Hits	10
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

ZN403_MOUSE
θ value	2.36792 (rank : 109)	NC score	0.015138 (rank : 106)
Query Neighborhood Hits	133	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q5SV77, Q5SV75, Q5SV76, Q5SV78, Q6GVH6, Q6P9J4, Q920N4	Gene names	Znf403, Ggnbp2, Zfp403
Domain Architecture	No domain graphic available
Description	Protein ZNF403 (Gametogenetin-binding protein 2) (Dioxin-inducible factor 3) (DIF-3).

MLL3_HUMAN
θ value	3.0926 (rank : 110)	NC score	0.007451 (rank : 114)
Query Neighborhood Hits	133	Target Neighborhood Hits	1644	Shared Neighborhood Hits	30
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

CHD9_MOUSE
θ value	4.03905 (rank : 111)	NC score	0.000787 (rank : 122)
Query Neighborhood Hits	133	Target Neighborhood Hits	427	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

MYO15_HUMAN
θ value	4.03905 (rank : 112)	NC score	0.001367 (rank : 121)
Query Neighborhood Hits	133	Target Neighborhood Hits	671	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

RGS3_HUMAN
θ value	4.03905 (rank : 113)	NC score	0.005257 (rank : 116)
Query Neighborhood Hits	133	Target Neighborhood Hits	1375	Shared Neighborhood Hits	17
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

TNR6A_HUMAN
θ value	4.03905 (rank : 114)	NC score	0.016322 (rank : 103)
Query Neighborhood Hits	133	Target Neighborhood Hits	343	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

ASXL1_HUMAN
θ value	5.27518 (rank : 115)	NC score	0.017410 (rank : 102)
Query Neighborhood Hits	133	Target Neighborhood Hits	260	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

NPBL_MOUSE
θ value	5.27518 (rank : 116)	NC score	-0.001170 (rank : 130)
Query Neighborhood Hits	133	Target Neighborhood Hits	1041	Shared Neighborhood Hits	16
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

SATB1_HUMAN
θ value	5.27518 (rank : 117)	NC score	0.008244 (rank : 112)
Query Neighborhood Hits	133	Target Neighborhood Hits	130	Shared Neighborhood Hits	7
SwissProt Accessions	Q01826	Gene names	SATB1
Domain Architecture
Description	DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1).

SATB1_MOUSE
θ value	5.27518 (rank : 118)	NC score	0.008445 (rank : 110)
Query Neighborhood Hits	133	Target Neighborhood Hits	130	Shared Neighborhood Hits	8
SwissProt Accessions	Q60611	Gene names	Satb1
Domain Architecture
Description	DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1).

TJAP1_MOUSE
θ value	5.27518 (rank : 119)	NC score	0.004036 (rank : 118)
Query Neighborhood Hits	133	Target Neighborhood Hits	295	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DCD5, Q8CFL7, Q8R5I2	Gene names	Tjap1, Pilt, Tjp4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

ZEP1_MOUSE
θ value	5.27518 (rank : 120)	NC score	-0.004679 (rank : 132)
Query Neighborhood Hits	133	Target Neighborhood Hits	1063	Shared Neighborhood Hits	12
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

ZN403_HUMAN
θ value	5.27518 (rank : 121)	NC score	0.013253 (rank : 107)
Query Neighborhood Hits	133	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H3C7, Q96T90, Q9GZR8, Q9H767	Gene names	ZNF403, LCRG1, LZK1
Domain Architecture	No domain graphic available
Description	Protein ZNF403 (Laryngeal carcinoma-related protein 1).

CENG3_HUMAN
θ value	6.88961 (rank : 122)	NC score	-0.002004 (rank : 131)
Query Neighborhood Hits	133	Target Neighborhood Hits	455	Shared Neighborhood Hits	4
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

LAD1_HUMAN
θ value	6.88961 (rank : 123)	NC score	0.003800 (rank : 119)
Query Neighborhood Hits	133	Target Neighborhood Hits	441	Shared Neighborhood Hits	9
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

SASH1_HUMAN
θ value	6.88961 (rank : 124)	NC score	0.004868 (rank : 117)
Query Neighborhood Hits	133	Target Neighborhood Hits	292	Shared Neighborhood Hits	7
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

SYNJ1_HUMAN
θ value	6.88961 (rank : 125)	NC score	0.008423 (rank : 111)
Query Neighborhood Hits	133	Target Neighborhood Hits	498	Shared Neighborhood Hits	14
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

FLNA_MOUSE
θ value	8.99809 (rank : 126)	NC score	0.000344 (rank : 123)
Query Neighborhood Hits	133	Target Neighborhood Hits	142	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BTM8, O54934, Q7TQI1, Q8BLK1, Q8BTN7, Q8VHX5, Q8VHX8, Q99KQ2	Gene names	Flna, Fln, Fln1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

MAML1_HUMAN
θ value	8.99809 (rank : 127)	NC score	0.005962 (rank : 115)
Query Neighborhood Hits	133	Target Neighborhood Hits	228	Shared Neighborhood Hits	10
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

NCOA3_HUMAN
θ value	8.99809 (rank : 128)	NC score	0.008034 (rank : 113)
Query Neighborhood Hits	133	Target Neighborhood Hits	171	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

NMDE4_HUMAN
θ value	8.99809 (rank : 129)	NC score	0.000047 (rank : 124)
Query Neighborhood Hits	133	Target Neighborhood Hits	133	Shared Neighborhood Hits	3
SwissProt Accessions	O15399	Gene names	GRIN2D
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D) (EB11).

PKDRE_MOUSE
θ value	8.99809 (rank : 130)	NC score	0.003046 (rank : 120)
Query Neighborhood Hits	133	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

RIMB1_MOUSE
θ value	8.99809 (rank : 131)	NC score	-0.006244 (rank : 133)
Query Neighborhood Hits	133	Target Neighborhood Hits	1376	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SHAN1_HUMAN
θ value	8.99809 (rank : 132)	NC score	-0.001021 (rank : 129)
Query Neighborhood Hits	133	Target Neighborhood Hits	1041	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

TF3A_HUMAN
θ value	8.99809 (rank : 133)	NC score	-0.006335 (rank : 134)
Query Neighborhood Hits	133	Target Neighborhood Hits	726	Shared Neighborhood Hits	6
SwissProt Accessions	Q92664, Q12963, Q13097	Gene names	GTF3A
Domain Architecture	No domain graphic available
Description	Transcription factor IIIA (Factor A) (TFIIIA).

DAX1_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.378334 (rank : 98)
Query Neighborhood Hits	133	Target Neighborhood Hits	65	Shared Neighborhood Hits	55
SwissProt Accessions	P51843, Q96F69	Gene names	NR0B1, AHC, DAX1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1) (DSS-AHC critical region on the X chromosome protein 1).

DAX1_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.401071 (rank : 97)
Query Neighborhood Hits	133	Target Neighborhood Hits	70	Shared Neighborhood Hits	56
SwissProt Accessions	Q61066, O09068, O09147	Gene names	Nr0b1, Ahch, Dax1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1).

SHP_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.412477 (rank : 95)
Query Neighborhood Hits	133	Target Neighborhood Hits	57	Shared Neighborhood Hits	52
SwissProt Accessions	Q15466, Q5QP36	Gene names	NR0B2, SHP
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

SHP_MOUSE
θ value	θ > 10 (rank : 137)	NC score	0.409031 (rank : 96)
Query Neighborhood Hits	133	Target Neighborhood Hits	53	Shared Neighborhood Hits	49
SwissProt Accessions	Q62227, Q53Z53	Gene names	Nr0b2, Shp
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

Hits sorted by NC score

ANDR_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	133	Target Neighborhood Hits	133	Shared Neighborhood Hits	133
SwissProt Accessions	P19091	Gene names	Ar, Nr3c4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

ANDR_HUMAN
NC score	0.997021 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	133	Target Neighborhood Hits	126	Shared Neighborhood Hits	95
SwissProt Accessions	P10275	Gene names	AR, DHTR, NR3C4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

GCR_HUMAN
NC score	0.980879 (rank : 3)	θ value	1.17728e-108 (rank : 6)
Query Neighborhood Hits	133	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P04150, P04151, Q53EP5, Q6N0A4	Gene names	NR3C1, GRL
Domain Architecture
Description	Glucocorticoid receptor (GR).

PRGR_HUMAN
NC score	0.980031 (rank : 4)	θ value	9.92011e-124 (rank : 3)
Query Neighborhood Hits	133	Target Neighborhood Hits	163	Shared Neighborhood Hits	95
SwissProt Accessions	P06401, Q9UPF7	Gene names	PGR, NR3C3
Domain Architecture
Description	Progesterone receptor (PR).

GCR_MOUSE
NC score	0.979958 (rank : 5)	θ value	7.14227e-106 (rank : 8)
Query Neighborhood Hits	133	Target Neighborhood Hits	117	Shared Neighborhood Hits	94
SwissProt Accessions	P06537, Q61628, Q61629	Gene names	Nr3c1, Grl, Grl1
Domain Architecture
Description	Glucocorticoid receptor (GR).

MCR_HUMAN
NC score	0.976063 (rank : 6)	θ value	6.24247e-110 (rank : 5)
Query Neighborhood Hits	133	Target Neighborhood Hits	149	Shared Neighborhood Hits	97
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

MCR_MOUSE
NC score	0.974448 (rank : 7)	θ value	2.6227e-108 (rank : 7)
Query Neighborhood Hits	133	Target Neighborhood Hits	162	Shared Neighborhood Hits	97
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

PRGR_MOUSE
NC score	0.973357 (rank : 8)	θ value	3.76964e-123 (rank : 4)
Query Neighborhood Hits	133	Target Neighborhood Hits	286	Shared Neighborhood Hits	99
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

ESR1_MOUSE
NC score	0.935814 (rank : 9)	θ value	1.16164e-39 (rank : 9)
Query Neighborhood Hits	133	Target Neighborhood Hits	104	Shared Neighborhood Hits	94
SwissProt Accessions	P19785, Q9JJT5, Q9QY51, Q9QY52	Gene names	Esr1, Esr, Estr, Estra, Nr3a1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

ESR2_MOUSE
NC score	0.935020 (rank : 10)	θ value	4.41421e-39 (rank : 11)
Query Neighborhood Hits	133	Target Neighborhood Hits	110	Shared Neighborhood Hits	94
SwissProt Accessions	O08537, O35635, O70519	Gene names	Esr2, Estrb, Nr3a2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

ESR2_HUMAN
NC score	0.934985 (rank : 11)	θ value	1.6774e-38 (rank : 12)
Query Neighborhood Hits	133	Target Neighborhood Hits	110	Shared Neighborhood Hits	94
SwissProt Accessions	Q92731, O60608, O60685, O60702, O60703, O75583, O75584, Q86Z31, Q9UEV6, Q9UHD3, Q9UQK9	Gene names	ESR2, ESTRB, NR3A2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

ESR1_HUMAN
NC score	0.934687 (rank : 12)	θ value	1.98146e-39 (rank : 10)
Query Neighborhood Hits	133	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P03372, Q13511, Q14276, Q9NU51, Q9UDZ7, Q9UIS7	Gene names	ESR1, ESR, NR3A1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

ERR1_HUMAN
NC score	0.928777 (rank : 13)	θ value	1.46948e-34 (rank : 17)
Query Neighborhood Hits	133	Target Neighborhood Hits	157	Shared Neighborhood Hits	94
SwissProt Accessions	P11474, Q14514	Gene names	ESRRA, ERR1, ESRL1, NR3B1
Domain Architecture
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR- alpha) (Estrogen receptor-like 1).

ERR2_HUMAN
NC score	0.926470 (rank : 14)	θ value	6.59618e-35 (rank : 16)
Query Neighborhood Hits	133	Target Neighborhood Hits	108	Shared Neighborhood Hits	94
SwissProt Accessions	O95718, Q9HCB4	Gene names	ESRRB, ERRB2, NR3B2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2) (ERR beta-2).

ERR2_MOUSE
NC score	0.926330 (rank : 15)	θ value	5.0505e-35 (rank : 15)
Query Neighborhood Hits	133	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	Q61539, O09067, O09146	Gene names	Esrrb, Err-2, Err2, Nr3b2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2).

ERR3_HUMAN
NC score	0.924220 (rank : 16)	θ value	5.96599e-36 (rank : 13)
Query Neighborhood Hits	133	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	P62508, O75454, O96021, Q68DA0, Q6P274, Q6PK28, Q6TS38, Q9R1F3, Q9UNJ4	Gene names	ESRRG, ERR3, ERRG2, KIAA0832, NR3B3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (ERR gamma-2).

ERR3_MOUSE
NC score	0.924220 (rank : 17)	θ value	5.96599e-36 (rank : 14)
Query Neighborhood Hits	133	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	P62509, O75454, O96021, Q8CHC9, Q9R1F3	Gene names	Esrrg, Err3, Kiaa0832, Nr3b3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3).

NR2E1_MOUSE
NC score	0.895198 (rank : 18)	θ value	2.20094e-22 (rank : 34)
Query Neighborhood Hits	133	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	Q64104	Gene names	Nr2e1, Tll, Tlx
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (mTll).

NR2E1_HUMAN
NC score	0.892001 (rank : 19)	θ value	6.40375e-22 (rank : 37)
Query Neighborhood Hits	133	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y466	Gene names	NR2E1, TLX
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (hTll).

NR2E3_MOUSE
NC score	0.891139 (rank : 20)	θ value	4.9032e-22 (rank : 36)
Query Neighborhood Hits	133	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	Q9QXZ7	Gene names	Nr2e3, Pnr, Rnr
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

HNF4G_HUMAN
NC score	0.888825 (rank : 21)	θ value	4.01107e-24 (rank : 25)
Query Neighborhood Hits	133	Target Neighborhood Hits	100	Shared Neighborhood Hits	94
SwissProt Accessions	Q14541, Q9UH81, Q9UIS6	Gene names	HNF4G, NR2A2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

HNF4G_MOUSE
NC score	0.888034 (rank : 22)	θ value	6.84181e-24 (rank : 26)
Query Neighborhood Hits	133	Target Neighborhood Hits	101	Shared Neighborhood Hits	94
SwissProt Accessions	Q9WUU6	Gene names	Hnf4g, Nr2a2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

RXRG_MOUSE
NC score	0.886217 (rank : 23)	θ value	2.77775e-25 (rank : 24)
Query Neighborhood Hits	133	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P28705	Gene names	Rxrg, Nr2b3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

RXRA_MOUSE
NC score	0.886162 (rank : 24)	θ value	7.30988e-26 (rank : 21)
Query Neighborhood Hits	133	Target Neighborhood Hits	129	Shared Neighborhood Hits	94
SwissProt Accessions	P28700	Gene names	Rxra, Nr2b1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

HNF4A_MOUSE
NC score	0.885593 (rank : 25)	θ value	4.9032e-22 (rank : 35)
Query Neighborhood Hits	133	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	P49698	Gene names	Hnf4a, Hnf-4, Hnf4, Nr2a1, Tcf14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

RXRG_HUMAN
NC score	0.884926 (rank : 26)	θ value	7.30988e-26 (rank : 22)
Query Neighborhood Hits	133	Target Neighborhood Hits	114	Shared Neighborhood Hits	94
SwissProt Accessions	P48443	Gene names	RXRG, NR2B3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

EAR2_HUMAN
NC score	0.884188 (rank : 27)	θ value	2.77775e-25 (rank : 23)
Query Neighborhood Hits	133	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	P10588, Q9BUE8	Gene names	NR2F6, EAR2, ERBAL2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

HNF4A_HUMAN
NC score	0.883953 (rank : 28)	θ value	7.0802e-21 (rank : 48)
Query Neighborhood Hits	133	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P41235, O00659, O00723, Q14540, Q92653, Q92654, Q92655, Q99864, Q9NQH0	Gene names	HNF4A, HNF4, NR2A1, TCF14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

NR2E3_HUMAN
NC score	0.883794 (rank : 29)	θ value	6.40375e-22 (rank : 38)
Query Neighborhood Hits	133	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y5X4, Q9UHM4	Gene names	NR2E3, PNR, RNR
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

EAR2_MOUSE
NC score	0.883478 (rank : 30)	θ value	7.56453e-23 (rank : 31)
Query Neighborhood Hits	133	Target Neighborhood Hits	104	Shared Neighborhood Hits	94
SwissProt Accessions	P43136, Q61504	Gene names	Nr2f6, Ear-2, Ear2, Erbal2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

RXRA_HUMAN
NC score	0.883451 (rank : 31)	θ value	5.59698e-26 (rank : 20)
Query Neighborhood Hits	133	Target Neighborhood Hits	223	Shared Neighborhood Hits	95
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

RXRB_MOUSE
NC score	0.883179 (rank : 32)	θ value	1.92365e-26 (rank : 19)
Query Neighborhood Hits	133	Target Neighborhood Hits	230	Shared Neighborhood Hits	102
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

NR4A1_HUMAN
NC score	0.881735 (rank : 33)	θ value	1.42661e-21 (rank : 39)
Query Neighborhood Hits	133	Target Neighborhood Hits	133	Shared Neighborhood Hits	95
SwissProt Accessions	P22736	Gene names	NR4A1, GFRP1, HMR, NAK1
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Early response protein NAK1) (TR3 orphan receptor) (ST-59).

NR4A3_HUMAN
NC score	0.881681 (rank : 34)	θ value	1.42661e-21 (rank : 40)
Query Neighborhood Hits	133	Target Neighborhood Hits	131	Shared Neighborhood Hits	97
SwissProt Accessions	Q92570, Q12935, Q14979, Q16420, Q4VXA9, Q9UEK2, Q9UEK3	Gene names	NR4A3, CHN, CSMF, MINOR, NOR1, TEC
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Nuclear hormone receptor NOR-1) (Neuron-derived orphan receptor 1) (Mitogen-induced nuclear orphan receptor).

NR4A3_MOUSE
NC score	0.880808 (rank : 35)	θ value	1.42661e-21 (rank : 41)
Query Neighborhood Hits	133	Target Neighborhood Hits	127	Shared Neighborhood Hits	96
SwissProt Accessions	Q9QZB6, Q9QZB5	Gene names	Nr4a3, Tec
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Orphan nuclear receptor TEC) (Translocated in extraskeletal chondrosarcoma).

NR4A1_MOUSE
NC score	0.880789 (rank : 36)	θ value	9.24701e-21 (rank : 49)
Query Neighborhood Hits	133	Target Neighborhood Hits	128	Shared Neighborhood Hits	94
SwissProt Accessions	P12813	Gene names	Nr4a1, Gfrp, Hmr, N10, Nur77
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Nuclear hormone receptor NUR/77) (N10 nuclear protein).

RXRB_HUMAN
NC score	0.880106 (rank : 37)	θ value	2.27234e-27 (rank : 18)
Query Neighborhood Hits	133	Target Neighborhood Hits	280	Shared Neighborhood Hits	101
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

NR4A2_HUMAN
NC score	0.879756 (rank : 38)	θ value	4.15078e-21 (rank : 42)
Query Neighborhood Hits	133	Target Neighborhood Hits	120	Shared Neighborhood Hits	96
SwissProt Accessions	P43354, Q16311	Gene names	NR4A2, NOT, NURR1, TINUR
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (Immediate-early response protein NOT) (Transcriptionally-inducible nuclear receptor).

COT2_HUMAN
NC score	0.879705 (rank : 39)	θ value	8.93572e-24 (rank : 27)
Query Neighborhood Hits	133	Target Neighborhood Hits	135	Shared Neighborhood Hits	94
SwissProt Accessions	P24468, Q03754	Gene names	NR2F2, ARP1, TFCOUP2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

COT2_MOUSE
NC score	0.879705 (rank : 40)	θ value	8.93572e-24 (rank : 28)
Query Neighborhood Hits	133	Target Neighborhood Hits	135	Shared Neighborhood Hits	94
SwissProt Accessions	P43135	Gene names	Nr2f2, Aporp1, Arp-1, Arp1, Tfcoup2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

NR4A2_MOUSE
NC score	0.879642 (rank : 41)	θ value	4.15078e-21 (rank : 43)
Query Neighborhood Hits	133	Target Neighborhood Hits	121	Shared Neighborhood Hits	96
SwissProt Accessions	Q06219, O08690	Gene names	Nr4a2, Nurr1
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (NUR- related factor 1).

NR1H4_HUMAN
NC score	0.879429 (rank : 42)	θ value	1.2077e-20 (rank : 52)
Query Neighborhood Hits	133	Target Neighborhood Hits	112	Shared Neighborhood Hits	95
SwissProt Accessions	Q96RI1, Q8NFP5, Q8NFP6, Q92943	Gene names	NR1H4, BAR, FXR, HRR1, RIP14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

NR1I3_MOUSE
NC score	0.878487 (rank : 43)	θ value	5.99374e-20 (rank : 58)
Query Neighborhood Hits	133	Target Neighborhood Hits	103	Shared Neighborhood Hits	95
SwissProt Accessions	O35627, O35628	Gene names	Nr1i3, Car
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Orphan nuclear receptor MB67).

COT1_MOUSE
NC score	0.877868 (rank : 44)	θ value	7.56453e-23 (rank : 30)
Query Neighborhood Hits	133	Target Neighborhood Hits	160	Shared Neighborhood Hits	94
SwissProt Accessions	Q60632, Q61438	Gene names	Nr2f1, Erbal3, Tfcoup1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I).

COT1_HUMAN
NC score	0.877576 (rank : 45)	θ value	7.56453e-23 (rank : 29)
Query Neighborhood Hits	133	Target Neighborhood Hits	159	Shared Neighborhood Hits	94
SwissProt Accessions	P10589	Gene names	NR2F1, EAR3, ERBAL3, TFCOUP1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I) (V-ERBA-related protein EAR-3).

NR1H4_MOUSE
NC score	0.877513 (rank : 46)	θ value	4.58923e-20 (rank : 57)
Query Neighborhood Hits	133	Target Neighborhood Hits	113	Shared Neighborhood Hits	95
SwissProt Accessions	Q60641, Q60642, Q60643	Gene names	Nr1h4, Bar, Fxr, Rip14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

NR1H3_HUMAN
NC score	0.877022 (rank : 47)	θ value	1.6852e-22 (rank : 33)
Query Neighborhood Hits	133	Target Neighborhood Hits	104	Shared Neighborhood Hits	94
SwissProt Accessions	Q13133, Q96H87	Gene names	NR1H3, LXRA
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

NR1H3_MOUSE
NC score	0.876936 (rank : 48)	θ value	1.29031e-22 (rank : 32)
Query Neighborhood Hits	133	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Z0Y9, Q9QUH7	Gene names	Nr1h3, Lxra
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

NR1I3_HUMAN
NC score	0.875923 (rank : 49)	θ value	1.63225e-17 (rank : 61)
Query Neighborhood Hits	133	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	Q14994	Gene names	NR1I3, CAR
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Constitutive activator of retinoid response) (Constitutive active response) (Orphan nuclear receptor MB67).

STF1_HUMAN
NC score	0.874964 (rank : 50)	θ value	1.63225e-17 (rank : 62)
Query Neighborhood Hits	133	Target Neighborhood Hits	132	Shared Neighborhood Hits	94
SwissProt Accessions	Q13285, O15196	Gene names	NR5A1, AD4BP, FTZF1, SF1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1).

STF1_MOUSE
NC score	0.874216 (rank : 51)	θ value	1.63225e-17 (rank : 63)
Query Neighborhood Hits	133	Target Neighborhood Hits	137	Shared Neighborhood Hits	95
SwissProt Accessions	P33242	Gene names	Nr5a1, Ftzf1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1) (Embryonal LTR-binding protein) (ELP) (Embryonal long terminal repeat- binding protein) (Steroid hydroxylase positive regulator).

NR6A1_HUMAN
NC score	0.871921 (rank : 52)	θ value	1.52774e-15 (rank : 67)
Query Neighborhood Hits	133	Target Neighborhood Hits	108	Shared Neighborhood Hits	94
SwissProt Accessions	Q15406, O00551, O00603, Q8NHQ0, Q92898, Q99802	Gene names	NR6A1, GCNF
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

RARG2_HUMAN
NC score	0.871690 (rank : 53)	θ value	4.15078e-21 (rank : 46)
Query Neighborhood Hits	133	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	P22932, Q15281	Gene names	RARG, NR1B3
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor gamma-2 (RAR-gamma-2).

RARG1_HUMAN
NC score	0.871672 (rank : 54)	θ value	4.15078e-21 (rank : 44)
Query Neighborhood Hits	133	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	P13631	Gene names	RARG, NR1B3
Domain Architecture
Description	Retinoic acid receptor gamma-1 (RAR-gamma-1).

RARG2_MOUSE
NC score	0.871469 (rank : 55)	θ value	4.15078e-21 (rank : 47)
Query Neighborhood Hits	133	Target Neighborhood Hits	114	Shared Neighborhood Hits	94
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

RARG1_MOUSE
NC score	0.871244 (rank : 56)	θ value	4.15078e-21 (rank : 45)
Query Neighborhood Hits	133	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

NR6A1_MOUSE
NC score	0.870514 (rank : 57)	θ value	1.52774e-15 (rank : 68)
Query Neighborhood Hits	133	Target Neighborhood Hits	110	Shared Neighborhood Hits	94
SwissProt Accessions	Q64249	Gene names	Nr6a1, Gcnf
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

NR5A2_MOUSE
NC score	0.869704 (rank : 58)	θ value	8.65492e-19 (rank : 59)
Query Neighborhood Hits	133	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	P45448	Gene names	Nr5a2, Lrh1
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Liver receptor homolog 1) (LRH-1).

RARA_HUMAN
NC score	0.868565 (rank : 59)	θ value	2.06002e-20 (rank : 55)
Query Neighborhood Hits	133	Target Neighborhood Hits	118	Shared Neighborhood Hits	94
SwissProt Accessions	P10276, P78456, Q13440, Q13441, Q9NQS0	Gene names	RARA, NR1B1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARB_HUMAN
NC score	0.868311 (rank : 60)	θ value	9.24701e-21 (rank : 50)
Query Neighborhood Hits	133	Target Neighborhood Hits	118	Shared Neighborhood Hits	94
SwissProt Accessions	P10826, P12891, Q00989, Q15298, Q9UN48	Gene names	RARB, HAP, NR1B2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta) (RAR-epsilon) (HBV-activated protein).

RARA_MOUSE
NC score	0.868168 (rank : 61)	θ value	2.69047e-20 (rank : 56)
Query Neighborhood Hits	133	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P11416, P22603	Gene names	Rara, Nr1b1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARB_MOUSE
NC score	0.868106 (rank : 62)	θ value	1.5773e-20 (rank : 54)
Query Neighborhood Hits	133	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	P22605, P11417, P22604	Gene names	Rarb, Nr1b2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta).

NR1H2_MOUSE
NC score	0.867293 (rank : 63)	θ value	1.2077e-20 (rank : 51)
Query Neighborhood Hits	133	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	Q60644	Gene names	Nr1h2, Lxrb, Rip15, Unr, Unr2
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Retinoid X receptor-interacting protein No.15).

NR5A2_HUMAN
NC score	0.866292 (rank : 64)	θ value	2.5182e-18 (rank : 60)
Query Neighborhood Hits	133	Target Neighborhood Hits	112	Shared Neighborhood Hits	94
SwissProt Accessions	O00482, O95642	Gene names	NR5A2, B1F, CPF, FTF
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Alpha-1-fetoprotein transcription factor) (Hepatocytic transcription factor) (B1-binding factor) (hB1F) (CYP7A promoter-binding factor) (Liver receptor homolog 1) (LRH-1).

NR1H2_HUMAN
NC score	0.862581 (rank : 65)	θ value	1.5773e-20 (rank : 53)
Query Neighborhood Hits	133	Target Neighborhood Hits	114	Shared Neighborhood Hits	94
SwissProt Accessions	P55055, Q12970	Gene names	NR1H2, LXRB, NER, UNR
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Nuclear receptor NER).

TR2_HUMAN
NC score	0.862542 (rank : 66)	θ value	9.90251e-15 (rank : 77)
Query Neighborhood Hits	133	Target Neighborhood Hits	110	Shared Neighborhood Hits	94
SwissProt Accessions	P13056	Gene names	NR2C1, TR2
Domain Architecture
Description	Orphan nuclear receptor TR2 (Testicular receptor 2).

PXR_MOUSE
NC score	0.851031 (rank : 67)	θ value	1.86753e-13 (rank : 84)
Query Neighborhood Hits	133	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	O54915	Gene names	Nr1i2, Pxr
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor).

VDR_MOUSE
NC score	0.849931 (rank : 68)	θ value	7.58209e-15 (rank : 75)
Query Neighborhood Hits	133	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	P48281	Gene names	Vdr, Nr1i1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

TR2_MOUSE
NC score	0.849250 (rank : 69)	θ value	5.8054e-15 (rank : 74)
Query Neighborhood Hits	133	Target Neighborhood Hits	100	Shared Neighborhood Hits	94
SwissProt Accessions	Q505F1, P97763, Q3UIJ7, Q4U1Z4, Q60927, Q62152, Q8VIJ3	Gene names	Nr2c1, Tr2, Tr2-11
Domain Architecture	No domain graphic available
Description	Orphan nuclear receptor TR2 (Testicular receptor 2) (mTR2).

VDR_HUMAN
NC score	0.848463 (rank : 70)	θ value	9.90251e-15 (rank : 78)
Query Neighborhood Hits	133	Target Neighborhood Hits	112	Shared Neighborhood Hits	94
SwissProt Accessions	P11473	Gene names	VDR, NR1I1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

NR1D1_HUMAN
NC score	0.847568 (rank : 71)	θ value	2.28291e-11 (rank : 91)
Query Neighborhood Hits	133	Target Neighborhood Hits	140	Shared Neighborhood Hits	96
SwissProt Accessions	P20393, Q15304	Gene names	NR1D1, EAR1, HREV, THRAL
Domain Architecture
Description	Orphan nuclear receptor NR1D1 (V-erbA-related protein EAR-1) (Rev- erbA-alpha).

TR4_HUMAN
NC score	0.847225 (rank : 72)	θ value	1.80466e-16 (rank : 64)
Query Neighborhood Hits	133	Target Neighborhood Hits	117	Shared Neighborhood Hits	94
SwissProt Accessions	P49116, P55092	Gene names	NR2C2, TAK1, TR4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

TR4_MOUSE
NC score	0.846865 (rank : 73)	θ value	2.35696e-16 (rank : 65)
Query Neighborhood Hits	133	Target Neighborhood Hits	115	Shared Neighborhood Hits	94
SwissProt Accessions	P49117, P55093	Gene names	Nr2c2, Mtr2r1, Tak1, Tr4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

THA_HUMAN
NC score	0.846828 (rank : 74)	θ value	1.42992e-13 (rank : 82)
Query Neighborhood Hits	133	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P10827, P21205, Q8N6A1, Q96H73	Gene names	THRA, ERBA1, NR1A1, THRA1
Domain Architecture
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1) (EAR-7) (EAR7).

THA_MOUSE
NC score	0.846494 (rank : 75)	θ value	1.86753e-13 (rank : 85)
Query Neighborhood Hits	133	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P63058, P10685, P15827, P16416, P37241, Q63107, Q63195, Q63196, Q99146	Gene names	Thra, C-erba-alpha, Nr1a1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1).

PXR_HUMAN
NC score	0.845890 (rank : 76)	θ value	3.52202e-12 (rank : 87)
Query Neighborhood Hits	133	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	O75469, Q96AC7, Q9UJ22, Q9UJ23, Q9UJ24, Q9UJ25, Q9UJ26, Q9UJ27	Gene names	NR1I2, PXR
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor) (Orphan nuclear receptor PAR1) (Steroid and xenobiotic receptor) (SXR).

RORB_MOUSE
NC score	0.845403 (rank : 77)	θ value	1.99529e-15 (rank : 70)
Query Neighborhood Hits	133	Target Neighborhood Hits	99	Shared Neighborhood Hits	94
SwissProt Accessions	Q8R1B8	Gene names	Rorb, Nr1f2
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

RORB_HUMAN
NC score	0.845238 (rank : 78)	θ value	1.99529e-15 (rank : 69)
Query Neighborhood Hits	133	Target Neighborhood Hits	99	Shared Neighborhood Hits	94
SwissProt Accessions	Q92753, Q8WX73	Gene names	RORB, NR1F2, RZRB
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

RORA_HUMAN
NC score	0.845119 (rank : 79)	θ value	8.95645e-16 (rank : 66)
Query Neighborhood Hits	133	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P35398, P35397, P35399, P45445, Q96H83	Gene names	RORA, NR1F1, RZRA
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

RORG_MOUSE
NC score	0.844738 (rank : 80)	θ value	5.8054e-15 (rank : 73)
Query Neighborhood Hits	133	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	P51450, Q61027, Q91YT5, Q9QXD9, Q9R177	Gene names	Rorc, Nr1f3, Rorg, Thor
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma) (Thymus orphan receptor) (TOR).

RORA_MOUSE
NC score	0.843650 (rank : 81)	θ value	2.60593e-15 (rank : 71)
Query Neighborhood Hits	133	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P51448, P70283, P97741, P97773, Q923G1	Gene names	Rora, Nr1f1, Rzra
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

RORG_HUMAN
NC score	0.839564 (rank : 82)	θ value	9.90251e-15 (rank : 76)
Query Neighborhood Hits	133	Target Neighborhood Hits	119	Shared Neighborhood Hits	94
SwissProt Accessions	P51449, Q8N5V7, Q8NCY8	Gene names	RORC, NR1F3, RORG, RZRG
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma).

NR1D2_HUMAN
NC score	0.839038 (rank : 83)	θ value	2.28291e-11 (rank : 92)
Query Neighborhood Hits	133	Target Neighborhood Hits	115	Shared Neighborhood Hits	94
SwissProt Accessions	Q14995, O00402, Q86XD4	Gene names	NR1D2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (EAR-1R) (Orphan nuclear hormone receptor BD73).

THB2_HUMAN
NC score	0.838790 (rank : 84)	θ value	3.40345e-15 (rank : 72)
Query Neighborhood Hits	133	Target Neighborhood Hits	104	Shared Neighborhood Hits	95
SwissProt Accessions	P37243	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor beta-2.

NR1D2_MOUSE
NC score	0.836604 (rank : 85)	θ value	2.28291e-11 (rank : 93)
Query Neighborhood Hits	133	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	Q60674, Q60646	Gene names	Nr1d2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (Orphan nuclear receptor RVR).

THB2_MOUSE
NC score	0.836276 (rank : 86)	θ value	1.68911e-14 (rank : 81)
Query Neighborhood Hits	133	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	P37244	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-2.

THB1_HUMAN
NC score	0.836138 (rank : 87)	θ value	1.29331e-14 (rank : 79)
Query Neighborhood Hits	133	Target Neighborhood Hits	106	Shared Neighborhood Hits	95
SwissProt Accessions	P10828, Q13986	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture
Description	Thyroid hormone receptor beta-1.

THB1_MOUSE
NC score	0.835823 (rank : 88)	θ value	1.68911e-14 (rank : 80)
Query Neighborhood Hits	133	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P37242	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-1.

PPARA_HUMAN
NC score	0.835566 (rank : 89)	θ value	1.86753e-13 (rank : 83)
Query Neighborhood Hits	133	Target Neighborhood Hits	100	Shared Neighborhood Hits	94
SwissProt Accessions	Q07869, Q16241, Q92486, Q92689, Q9Y3N1	Gene names	PPARA, NR1C1, PPAR
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

PPARA_MOUSE
NC score	0.834447 (rank : 90)	θ value	5.43371e-13 (rank : 86)
Query Neighborhood Hits	133	Target Neighborhood Hits	99	Shared Neighborhood Hits	94
SwissProt Accessions	P23204	Gene names	Ppara, Nr1c1, Ppar
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

PPARG_HUMAN
NC score	0.831280 (rank : 91)	θ value	4.59992e-12 (rank : 88)
Query Neighborhood Hits	133	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37231, O00684, O00710, O14515, Q15178, Q15179, Q15180, Q15832, Q86U60, Q96J12	Gene names	PPARG, NR1C3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

PPARG_MOUSE
NC score	0.830024 (rank : 92)	θ value	1.33837e-11 (rank : 90)
Query Neighborhood Hits	133	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37238	Gene names	Pparg, Nr1c3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

PPARD_HUMAN
NC score	0.827616 (rank : 93)	θ value	1.33837e-11 (rank : 89)
Query Neighborhood Hits	133	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q03181, Q7Z5K0, Q9BUD4	Gene names	PPARD, NR1C2, PPARB
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1) (NUCI).

PPARD_MOUSE
NC score	0.824577 (rank : 94)	θ value	3.89403e-11 (rank : 94)
Query Neighborhood Hits	133	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	P35396, P37239	Gene names	Ppard, Nr1c2, Pparb
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1).

SHP_HUMAN
NC score	0.412477 (rank : 95)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	133	Target Neighborhood Hits	57	Shared Neighborhood Hits	52
SwissProt Accessions	Q15466, Q5QP36	Gene names	NR0B2, SHP
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

SHP_MOUSE
NC score	0.409031 (rank : 96)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	133	Target Neighborhood Hits	53	Shared Neighborhood Hits	49
SwissProt Accessions	Q62227, Q53Z53	Gene names	Nr0b2, Shp
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

DAX1_MOUSE
NC score	0.401071 (rank : 97)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	133	Target Neighborhood Hits	70	Shared Neighborhood Hits	56
SwissProt Accessions	Q61066, O09068, O09147	Gene names	Nr0b1, Ahch, Dax1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1).

DAX1_HUMAN
NC score	0.378334 (rank : 98)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	133	Target Neighborhood Hits	65	Shared Neighborhood Hits	55
SwissProt Accessions	P51843, Q96F69	Gene names	NR0B1, AHC, DAX1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1) (DSS-AHC critical region on the X chromosome protein 1).

BAT2_HUMAN
NC score	0.029786 (rank : 99)	θ value	0.0961366 (rank : 96)
Query Neighborhood Hits	133	Target Neighborhood Hits	931	Shared Neighborhood Hits	20
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAT2_MOUSE
NC score	0.026561 (rank : 100)	θ value	0.163984 (rank : 97)
Query Neighborhood Hits	133	Target Neighborhood Hits	947	Shared Neighborhood Hits	18
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

MA1B1_HUMAN
NC score	0.022192 (rank : 101)	θ value	0.0113563 (rank : 95)
Query Neighborhood Hits	133	Target Neighborhood Hits	125	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UKM7, Q5VSG3, Q9BRS9, Q9Y5K7	Gene names	MAN1B1
Domain Architecture
Description	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific-processing alpha-mannosidase).

ASXL1_HUMAN
NC score	0.017410 (rank : 102)	θ value	5.27518 (rank : 115)
Query Neighborhood Hits	133	Target Neighborhood Hits	260	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

TNR6A_HUMAN
NC score	0.016322 (rank : 103)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	133	Target Neighborhood Hits	343	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

ALO17_HUMAN
NC score	0.015771 (rank : 104)	θ value	0.813845 (rank : 102)
Query Neighborhood Hits	133	Target Neighborhood Hits	317	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

NCOA2_HUMAN
NC score	0.015753 (rank : 105)	θ value	1.06291 (rank : 103)
Query Neighborhood Hits	133	Target Neighborhood Hits	281	Shared Neighborhood Hits	12
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

ZN403_MOUSE
NC score	0.015138 (rank : 106)	θ value	2.36792 (rank : 109)
Query Neighborhood Hits	133	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q5SV77, Q5SV75, Q5SV76, Q5SV78, Q6GVH6, Q6P9J4, Q920N4	Gene names	Znf403, Ggnbp2, Zfp403
Domain Architecture	No domain graphic available
Description	Protein ZNF403 (Gametogenetin-binding protein 2) (Dioxin-inducible factor 3) (DIF-3).

ZN403_HUMAN
NC score	0.013253 (rank : 107)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	133	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H3C7, Q96T90, Q9GZR8, Q9H767	Gene names	ZNF403, LCRG1, LZK1
Domain Architecture	No domain graphic available
Description	Protein ZNF403 (Laryngeal carcinoma-related protein 1).

NCOA2_MOUSE
NC score	0.011458 (rank : 108)	θ value	2.36792 (rank : 108)
Query Neighborhood Hits	133	Target Neighborhood Hits	281	Shared Neighborhood Hits	10
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

RGS3_MOUSE
NC score	0.009204 (rank : 109)	θ value	0.47712 (rank : 100)
Query Neighborhood Hits	133	Target Neighborhood Hits	1621	Shared Neighborhood Hits	23
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SATB1_MOUSE
NC score	0.008445 (rank : 110)	θ value	5.27518 (rank : 118)
Query Neighborhood Hits	133	Target Neighborhood Hits	130	Shared Neighborhood Hits	8
SwissProt Accessions	Q60611	Gene names	Satb1
Domain Architecture
Description	DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1).

SYNJ1_HUMAN
NC score	0.008423 (rank : 111)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	133	Target Neighborhood Hits	498	Shared Neighborhood Hits	14
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SATB1_HUMAN
NC score	0.008244 (rank : 112)	θ value	5.27518 (rank : 117)
Query Neighborhood Hits	133	Target Neighborhood Hits	130	Shared Neighborhood Hits	7
SwissProt Accessions	Q01826	Gene names	SATB1
Domain Architecture
Description	DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1).

NCOA3_HUMAN
NC score	0.008034 (rank : 113)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	133	Target Neighborhood Hits	171	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

MLL3_HUMAN
NC score	0.007451 (rank : 114)	θ value	3.0926 (rank : 110)
Query Neighborhood Hits	133	Target Neighborhood Hits	1644	Shared Neighborhood Hits	30
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MAML1_HUMAN
NC score	0.005962 (rank : 115)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	133	Target Neighborhood Hits	228	Shared Neighborhood Hits	10
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

RGS3_HUMAN
NC score	0.005257 (rank : 116)	θ value	4.03905 (rank : 113)
Query Neighborhood Hits	133	Target Neighborhood Hits	1375	Shared Neighborhood Hits	17
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SASH1_HUMAN
NC score	0.004868 (rank : 117)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	133	Target Neighborhood Hits	292	Shared Neighborhood Hits	7
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

TJAP1_MOUSE
NC score	0.004036 (rank : 118)	θ value	5.27518 (rank : 119)
Query Neighborhood Hits	133	Target Neighborhood Hits	295	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DCD5, Q8CFL7, Q8R5I2	Gene names	Tjap1, Pilt, Tjp4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

LAD1_HUMAN
NC score	0.003800 (rank : 119)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	133	Target Neighborhood Hits	441	Shared Neighborhood Hits	9
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

PKDRE_MOUSE
NC score	0.003046 (rank : 120)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	133	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

MYO15_HUMAN
NC score	0.001367 (rank : 121)	θ value	4.03905 (rank : 112)
Query Neighborhood Hits	133	Target Neighborhood Hits	671	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

CHD9_MOUSE
NC score	0.000787 (rank : 122)	θ value	4.03905 (rank : 111)
Query Neighborhood Hits	133	Target Neighborhood Hits	427	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

FLNA_MOUSE
NC score	0.000344 (rank : 123)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	133	Target Neighborhood Hits	142	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BTM8, O54934, Q7TQI1, Q8BLK1, Q8BTN7, Q8VHX5, Q8VHX8, Q99KQ2	Gene names	Flna, Fln, Fln1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

NMDE4_HUMAN
NC score	0.000047 (rank : 124)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	133	Target Neighborhood Hits	133	Shared Neighborhood Hits	3
SwissProt Accessions	O15399	Gene names	GRIN2D
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D) (EB11).

GLI2_HUMAN
NC score	-0.000003 (rank : 125)	θ value	0.62314 (rank : 101)
Query Neighborhood Hits	133	Target Neighborhood Hits	971	Shared Neighborhood Hits	17
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

GLI3_HUMAN
NC score	-0.000267 (rank : 126)	θ value	0.163984 (rank : 98)
Query Neighborhood Hits	133	Target Neighborhood Hits	871	Shared Neighborhood Hits	10
SwissProt Accessions	P10071, O75219, Q9UDT5, Q9UJ39	Gene names	GLI3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.

LBX1_HUMAN
NC score	-0.000701 (rank : 127)	θ value	1.38821 (rank : 105)
Query Neighborhood Hits	133	Target Neighborhood Hits	357	Shared Neighborhood Hits	2
SwissProt Accessions	P52954	Gene names	LBX1
Domain Architecture
Description	Transcription factor LBX1.

GLI3_MOUSE
NC score	-0.000785 (rank : 128)	θ value	0.47712 (rank : 99)
Query Neighborhood Hits	133	Target Neighborhood Hits	807	Shared Neighborhood Hits	8
SwissProt Accessions	Q61602	Gene names	Gli3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.

SHAN1_HUMAN
NC score	-0.001021 (rank : 129)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	133	Target Neighborhood Hits	1041	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

NPBL_MOUSE
NC score	-0.001170 (rank : 130)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	133	Target Neighborhood Hits	1041	Shared Neighborhood Hits	16
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

CENG3_HUMAN
NC score	-0.002004 (rank : 131)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	133	Target Neighborhood Hits	455	Shared Neighborhood Hits	4
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

ZEP1_MOUSE
NC score	-0.004679 (rank : 132)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	133	Target Neighborhood Hits	1063	Shared Neighborhood Hits	12
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

RIMB1_MOUSE
NC score	-0.006244 (rank : 133)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	133	Target Neighborhood Hits	1376	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

TF3A_HUMAN
NC score	-0.006335 (rank : 134)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	133	Target Neighborhood Hits	726	Shared Neighborhood Hits	6
SwissProt Accessions	Q92664, Q12963, Q13097	Gene names	GTF3A
Domain Architecture	No domain graphic available
Description	Transcription factor IIIA (Factor A) (TFIIIA).

EPHA1_HUMAN
NC score	-0.006407 (rank : 135)	θ value	1.38821 (rank : 104)
Query Neighborhood Hits	133	Target Neighborhood Hits	997	Shared Neighborhood Hits	4
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

PAK4_MOUSE
NC score	-0.007377 (rank : 136)	θ value	1.38821 (rank : 106)
Query Neighborhood Hits	133	Target Neighborhood Hits	1098	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

GOGB1_HUMAN
NC score	-0.008480 (rank : 137)	θ value	1.81305 (rank : 107)
Query Neighborhood Hits	133	Target Neighborhood Hits	2297	Shared Neighborhood Hits	7
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).