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Network neighborhood for query Sequence : PRGR_HUMAN

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PRGR_HUMAN
SwissProt Accessions	P06401, Q9UPF7	Gene names	PGR, NR3C3
Domain Architecture
Description	Progesterone receptor (PR).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PRGR_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	163	Target Neighborhood Hits	163	Shared Neighborhood Hits	163
SwissProt Accessions	P06401, Q9UPF7	Gene names	PGR, NR3C3
Domain Architecture
Description	Progesterone receptor (PR).

PRGR_MOUSE
θ value	0 (rank : 2)	NC score	0.987492 (rank : 2)
Query Neighborhood Hits	163	Target Neighborhood Hits	286	Shared Neighborhood Hits	106
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

ANDR_MOUSE
θ value	9.92011e-124 (rank : 3)	NC score	0.980031 (rank : 6)
Query Neighborhood Hits	163	Target Neighborhood Hits	133	Shared Neighborhood Hits	95
SwissProt Accessions	P19091	Gene names	Ar, Nr3c4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

MCR_HUMAN
θ value	1.21265e-121 (rank : 4)	NC score	0.977066 (rank : 7)
Query Neighborhood Hits	163	Target Neighborhood Hits	149	Shared Neighborhood Hits	97
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

ANDR_HUMAN
θ value	6.01832e-121 (rank : 5)	NC score	0.981228 (rank : 4)
Query Neighborhood Hits	163	Target Neighborhood Hits	126	Shared Neighborhood Hits	97
SwissProt Accessions	P10275	Gene names	AR, DHTR, NR3C4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

GCR_MOUSE
θ value	1.48236e-119 (rank : 6)	NC score	0.981169 (rank : 5)
Query Neighborhood Hits	163	Target Neighborhood Hits	117	Shared Neighborhood Hits	95
SwissProt Accessions	P06537, Q61628, Q61629	Gene names	Nr3c1, Grl, Grl1
Domain Architecture
Description	Glucocorticoid receptor (GR).

GCR_HUMAN
θ value	5.63297e-119 (rank : 7)	NC score	0.981583 (rank : 3)
Query Neighborhood Hits	163	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P04150, P04151, Q53EP5, Q6N0A4	Gene names	NR3C1, GRL
Domain Architecture
Description	Glucocorticoid receptor (GR).

MCR_MOUSE
θ value	1.43579e-114 (rank : 8)	NC score	0.975826 (rank : 8)
Query Neighborhood Hits	163	Target Neighborhood Hits	162	Shared Neighborhood Hits	99
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

ERR2_HUMAN
θ value	1.19932e-44 (rank : 9)	NC score	0.927265 (rank : 14)
Query Neighborhood Hits	163	Target Neighborhood Hits	108	Shared Neighborhood Hits	96
SwissProt Accessions	O95718, Q9HCB4	Gene names	ESRRB, ERRB2, NR3B2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2) (ERR beta-2).

ERR2_MOUSE
θ value	4.55743e-44 (rank : 10)	NC score	0.926740 (rank : 15)
Query Neighborhood Hits	163	Target Neighborhood Hits	109	Shared Neighborhood Hits	96
SwissProt Accessions	Q61539, O09067, O09146	Gene names	Esrrb, Err-2, Err2, Nr3b2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2).

ERR3_HUMAN
θ value	5.95217e-44 (rank : 11)	NC score	0.924478 (rank : 16)
Query Neighborhood Hits	163	Target Neighborhood Hits	106	Shared Neighborhood Hits	96
SwissProt Accessions	P62508, O75454, O96021, Q68DA0, Q6P274, Q6PK28, Q6TS38, Q9R1F3, Q9UNJ4	Gene names	ESRRG, ERR3, ERRG2, KIAA0832, NR3B3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (ERR gamma-2).

ERR3_MOUSE
θ value	5.95217e-44 (rank : 12)	NC score	0.924478 (rank : 17)
Query Neighborhood Hits	163	Target Neighborhood Hits	106	Shared Neighborhood Hits	96
SwissProt Accessions	P62509, O75454, O96021, Q8CHC9, Q9R1F3	Gene names	Esrrg, Err3, Kiaa0832, Nr3b3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3).

ESR2_HUMAN
θ value	7.27602e-42 (rank : 13)	NC score	0.932677 (rank : 12)
Query Neighborhood Hits	163	Target Neighborhood Hits	110	Shared Neighborhood Hits	96
SwissProt Accessions	Q92731, O60608, O60685, O60702, O60703, O75583, O75584, Q86Z31, Q9UEV6, Q9UHD3, Q9UQK9	Gene names	ESR2, ESTRB, NR3A2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

ESR2_MOUSE
θ value	6.15952e-41 (rank : 14)	NC score	0.932818 (rank : 11)
Query Neighborhood Hits	163	Target Neighborhood Hits	110	Shared Neighborhood Hits	96
SwissProt Accessions	O08537, O35635, O70519	Gene names	Esr2, Estrb, Nr3a2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

ESR1_MOUSE
θ value	1.3722e-40 (rank : 15)	NC score	0.934242 (rank : 9)
Query Neighborhood Hits	163	Target Neighborhood Hits	104	Shared Neighborhood Hits	94
SwissProt Accessions	P19785, Q9JJT5, Q9QY51, Q9QY52	Gene names	Esr1, Esr, Estr, Estra, Nr3a1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

ESR1_HUMAN
θ value	3.05695e-40 (rank : 16)	NC score	0.932994 (rank : 10)
Query Neighborhood Hits	163	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P03372, Q13511, Q14276, Q9NU51, Q9UDZ7, Q9UIS7	Gene names	ESR1, ESR, NR3A1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

ERR1_HUMAN
θ value	8.89434e-40 (rank : 17)	NC score	0.929637 (rank : 13)
Query Neighborhood Hits	163	Target Neighborhood Hits	157	Shared Neighborhood Hits	99
SwissProt Accessions	P11474, Q14514	Gene names	ESRRA, ERR1, ESRL1, NR3B1
Domain Architecture
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR- alpha) (Estrogen receptor-like 1).

HNF4G_HUMAN
θ value	8.08199e-25 (rank : 18)	NC score	0.881838 (rank : 21)
Query Neighborhood Hits	163	Target Neighborhood Hits	100	Shared Neighborhood Hits	96
SwissProt Accessions	Q14541, Q9UH81, Q9UIS6	Gene names	HNF4G, NR2A2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

RXRA_MOUSE
θ value	1.80048e-24 (rank : 19)	NC score	0.877533 (rank : 26)
Query Neighborhood Hits	163	Target Neighborhood Hits	129	Shared Neighborhood Hits	98
SwissProt Accessions	P28700	Gene names	Rxra, Nr2b1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

RXRA_HUMAN
θ value	2.35151e-24 (rank : 20)	NC score	0.874716 (rank : 31)
Query Neighborhood Hits	163	Target Neighborhood Hits	223	Shared Neighborhood Hits	98
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

RXRG_HUMAN
θ value	2.35151e-24 (rank : 21)	NC score	0.876089 (rank : 29)
Query Neighborhood Hits	163	Target Neighborhood Hits	114	Shared Neighborhood Hits	96
SwissProt Accessions	P48443	Gene names	RXRG, NR2B3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

RXRG_MOUSE
θ value	4.01107e-24 (rank : 22)	NC score	0.877829 (rank : 25)
Query Neighborhood Hits	163	Target Neighborhood Hits	113	Shared Neighborhood Hits	96
SwissProt Accessions	P28705	Gene names	Rxrg, Nr2b3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

HNF4G_MOUSE
θ value	5.23862e-24 (rank : 23)	NC score	0.881089 (rank : 22)
Query Neighborhood Hits	163	Target Neighborhood Hits	101	Shared Neighborhood Hits	96
SwissProt Accessions	Q9WUU6	Gene names	Hnf4g, Nr2a2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

NR2E1_MOUSE
θ value	6.84181e-24 (rank : 24)	NC score	0.889143 (rank : 18)
Query Neighborhood Hits	163	Target Neighborhood Hits	106	Shared Neighborhood Hits	96
SwissProt Accessions	Q64104	Gene names	Nr2e1, Tll, Tlx
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (mTll).

HNF4A_MOUSE
θ value	1.16704e-23 (rank : 25)	NC score	0.879650 (rank : 23)
Query Neighborhood Hits	163	Target Neighborhood Hits	103	Shared Neighborhood Hits	96
SwissProt Accessions	P49698	Gene names	Hnf4a, Hnf-4, Hnf4, Nr2a1, Tcf14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

NR2E3_MOUSE
θ value	1.5242e-23 (rank : 26)	NC score	0.883904 (rank : 20)
Query Neighborhood Hits	163	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	Q9QXZ7	Gene names	Nr2e3, Pnr, Rnr
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

EAR2_MOUSE
θ value	2.59989e-23 (rank : 27)	NC score	0.876363 (rank : 28)
Query Neighborhood Hits	163	Target Neighborhood Hits	104	Shared Neighborhood Hits	96
SwissProt Accessions	P43136, Q61504	Gene names	Nr2f6, Ear-2, Ear2, Erbal2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

EAR2_HUMAN
θ value	2.20094e-22 (rank : 28)	NC score	0.876614 (rank : 27)
Query Neighborhood Hits	163	Target Neighborhood Hits	106	Shared Neighborhood Hits	96
SwissProt Accessions	P10588, Q9BUE8	Gene names	NR2F6, EAR2, ERBAL2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

HNF4A_HUMAN
θ value	2.20094e-22 (rank : 29)	NC score	0.877972 (rank : 24)
Query Neighborhood Hits	163	Target Neighborhood Hits	105	Shared Neighborhood Hits	96
SwissProt Accessions	P41235, O00659, O00723, Q14540, Q92653, Q92654, Q92655, Q99864, Q9NQH0	Gene names	HNF4A, HNF4, NR2A1, TCF14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

NR2E1_HUMAN
θ value	8.36355e-22 (rank : 30)	NC score	0.886719 (rank : 19)
Query Neighborhood Hits	163	Target Neighborhood Hits	103	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y466	Gene names	NR2E1, TLX
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (hTll).

COT1_HUMAN
θ value	1.86321e-21 (rank : 31)	NC score	0.869138 (rank : 47)
Query Neighborhood Hits	163	Target Neighborhood Hits	159	Shared Neighborhood Hits	96
SwissProt Accessions	P10589	Gene names	NR2F1, EAR3, ERBAL3, TFCOUP1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I) (V-ERBA-related protein EAR-3).

COT1_MOUSE
θ value	1.86321e-21 (rank : 32)	NC score	0.869424 (rank : 46)
Query Neighborhood Hits	163	Target Neighborhood Hits	160	Shared Neighborhood Hits	96
SwissProt Accessions	Q60632, Q61438	Gene names	Nr2f1, Erbal3, Tfcoup1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I).

COT2_HUMAN
θ value	2.43343e-21 (rank : 33)	NC score	0.870988 (rank : 39)
Query Neighborhood Hits	163	Target Neighborhood Hits	135	Shared Neighborhood Hits	98
SwissProt Accessions	P24468, Q03754	Gene names	NR2F2, ARP1, TFCOUP2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

COT2_MOUSE
θ value	2.43343e-21 (rank : 34)	NC score	0.870988 (rank : 40)
Query Neighborhood Hits	163	Target Neighborhood Hits	135	Shared Neighborhood Hits	98
SwissProt Accessions	P43135	Gene names	Nr2f2, Aporp1, Arp-1, Arp1, Tfcoup2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

RARA_HUMAN
θ value	5.42112e-21 (rank : 35)	NC score	0.860399 (rank : 60)
Query Neighborhood Hits	163	Target Neighborhood Hits	118	Shared Neighborhood Hits	96
SwissProt Accessions	P10276, P78456, Q13440, Q13441, Q9NQS0	Gene names	RARA, NR1B1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARA_MOUSE
θ value	1.5773e-20 (rank : 36)	NC score	0.859886 (rank : 61)
Query Neighborhood Hits	163	Target Neighborhood Hits	113	Shared Neighborhood Hits	96
SwissProt Accessions	P11416, P22603	Gene names	Rara, Nr1b1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARG1_HUMAN
θ value	2.06002e-20 (rank : 37)	NC score	0.863394 (rank : 55)
Query Neighborhood Hits	163	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	P13631	Gene names	RARG, NR1B3
Domain Architecture
Description	Retinoic acid receptor gamma-1 (RAR-gamma-1).

RARG1_MOUSE
θ value	2.06002e-20 (rank : 38)	NC score	0.862893 (rank : 59)
Query Neighborhood Hits	163	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

RARG2_HUMAN
θ value	2.06002e-20 (rank : 39)	NC score	0.863329 (rank : 57)
Query Neighborhood Hits	163	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	P22932, Q15281	Gene names	RARG, NR1B3
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor gamma-2 (RAR-gamma-2).

RARG2_MOUSE
θ value	2.06002e-20 (rank : 40)	NC score	0.863031 (rank : 58)
Query Neighborhood Hits	163	Target Neighborhood Hits	114	Shared Neighborhood Hits	94
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

NR4A1_HUMAN
θ value	3.51386e-20 (rank : 41)	NC score	0.873461 (rank : 32)
Query Neighborhood Hits	163	Target Neighborhood Hits	133	Shared Neighborhood Hits	97
SwissProt Accessions	P22736	Gene names	NR4A1, GFRP1, HMR, NAK1
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Early response protein NAK1) (TR3 orphan receptor) (ST-59).

NR5A2_MOUSE
θ value	5.99374e-20 (rank : 42)	NC score	0.866301 (rank : 50)
Query Neighborhood Hits	163	Target Neighborhood Hits	107	Shared Neighborhood Hits	96
SwissProt Accessions	P45448	Gene names	Nr5a2, Lrh1
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Liver receptor homolog 1) (LRH-1).

NR5A2_HUMAN
θ value	7.82807e-20 (rank : 43)	NC score	0.863333 (rank : 56)
Query Neighborhood Hits	163	Target Neighborhood Hits	112	Shared Neighborhood Hits	96
SwissProt Accessions	O00482, O95642	Gene names	NR5A2, B1F, CPF, FTF
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Alpha-1-fetoprotein transcription factor) (Hepatocytic transcription factor) (B1-binding factor) (hB1F) (CYP7A promoter-binding factor) (Liver receptor homolog 1) (LRH-1).

NR4A1_MOUSE
θ value	1.02238e-19 (rank : 44)	NC score	0.872771 (rank : 34)
Query Neighborhood Hits	163	Target Neighborhood Hits	128	Shared Neighborhood Hits	96
SwissProt Accessions	P12813	Gene names	Nr4a1, Gfrp, Hmr, N10, Nur77
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Nuclear hormone receptor NUR/77) (N10 nuclear protein).

NR1H4_HUMAN
θ value	3.88503e-19 (rank : 45)	NC score	0.869029 (rank : 48)
Query Neighborhood Hits	163	Target Neighborhood Hits	112	Shared Neighborhood Hits	96
SwissProt Accessions	Q96RI1, Q8NFP5, Q8NFP6, Q92943	Gene names	NR1H4, BAR, FXR, HRR1, RIP14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

RARB_HUMAN
θ value	6.62687e-19 (rank : 46)	NC score	0.859377 (rank : 62)
Query Neighborhood Hits	163	Target Neighborhood Hits	118	Shared Neighborhood Hits	94
SwissProt Accessions	P10826, P12891, Q00989, Q15298, Q9UN48	Gene names	RARB, HAP, NR1B2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta) (RAR-epsilon) (HBV-activated protein).

NR4A2_HUMAN
θ value	8.65492e-19 (rank : 47)	NC score	0.870641 (rank : 42)
Query Neighborhood Hits	163	Target Neighborhood Hits	120	Shared Neighborhood Hits	96
SwissProt Accessions	P43354, Q16311	Gene names	NR4A2, NOT, NURR1, TINUR
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (Immediate-early response protein NOT) (Transcriptionally-inducible nuclear receptor).

NR4A2_MOUSE
θ value	8.65492e-19 (rank : 48)	NC score	0.870489 (rank : 43)
Query Neighborhood Hits	163	Target Neighborhood Hits	121	Shared Neighborhood Hits	96
SwissProt Accessions	Q06219, O08690	Gene names	Nr4a2, Nurr1
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (NUR- related factor 1).

RARB_MOUSE
θ value	8.65492e-19 (rank : 49)	NC score	0.859103 (rank : 63)
Query Neighborhood Hits	163	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	P22605, P11417, P22604	Gene names	Rarb, Nr1b2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta).

NR4A3_HUMAN
θ value	2.5182e-18 (rank : 50)	NC score	0.873155 (rank : 33)
Query Neighborhood Hits	163	Target Neighborhood Hits	131	Shared Neighborhood Hits	100
SwissProt Accessions	Q92570, Q12935, Q14979, Q16420, Q4VXA9, Q9UEK2, Q9UEK3	Gene names	NR4A3, CHN, CSMF, MINOR, NOR1, TEC
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Nuclear hormone receptor NOR-1) (Neuron-derived orphan receptor 1) (Mitogen-induced nuclear orphan receptor).

NR1H3_HUMAN
θ value	3.28887e-18 (rank : 51)	NC score	0.864329 (rank : 54)
Query Neighborhood Hits	163	Target Neighborhood Hits	104	Shared Neighborhood Hits	94
SwissProt Accessions	Q13133, Q96H87	Gene names	NR1H3, LXRA
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

STF1_HUMAN
θ value	3.28887e-18 (rank : 52)	NC score	0.872297 (rank : 35)
Query Neighborhood Hits	163	Target Neighborhood Hits	132	Shared Neighborhood Hits	99
SwissProt Accessions	Q13285, O15196	Gene names	NR5A1, AD4BP, FTZF1, SF1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1).

STF1_MOUSE
θ value	3.28887e-18 (rank : 53)	NC score	0.871959 (rank : 36)
Query Neighborhood Hits	163	Target Neighborhood Hits	137	Shared Neighborhood Hits	98
SwissProt Accessions	P33242	Gene names	Nr5a1, Ftzf1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1) (Embryonal LTR-binding protein) (ELP) (Embryonal long terminal repeat- binding protein) (Steroid hydroxylase positive regulator).

NR4A3_MOUSE
θ value	7.32683e-18 (rank : 54)	NC score	0.871411 (rank : 38)
Query Neighborhood Hits	163	Target Neighborhood Hits	127	Shared Neighborhood Hits	98
SwissProt Accessions	Q9QZB6, Q9QZB5	Gene names	Nr4a3, Tec
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Orphan nuclear receptor TEC) (Translocated in extraskeletal chondrosarcoma).

NR1H3_MOUSE
θ value	1.63225e-17 (rank : 55)	NC score	0.864437 (rank : 53)
Query Neighborhood Hits	163	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Z0Y9, Q9QUH7	Gene names	Nr1h3, Lxra
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

NR1I3_HUMAN
θ value	2.13179e-17 (rank : 56)	NC score	0.870252 (rank : 45)
Query Neighborhood Hits	163	Target Neighborhood Hits	107	Shared Neighborhood Hits	96
SwissProt Accessions	Q14994	Gene names	NR1I3, CAR
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Constitutive activator of retinoid response) (Constitutive active response) (Orphan nuclear receptor MB67).

NR1H2_MOUSE
θ value	8.10077e-17 (rank : 57)	NC score	0.857263 (rank : 65)
Query Neighborhood Hits	163	Target Neighborhood Hits	109	Shared Neighborhood Hits	97
SwissProt Accessions	Q60644	Gene names	Nr1h2, Lxrb, Rip15, Unr, Unr2
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Retinoid X receptor-interacting protein No.15).

NR1H2_HUMAN
θ value	1.38178e-16 (rank : 58)	NC score	0.853496 (rank : 66)
Query Neighborhood Hits	163	Target Neighborhood Hits	114	Shared Neighborhood Hits	96
SwissProt Accessions	P55055, Q12970	Gene names	NR1H2, LXRB, NER, UNR
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Nuclear receptor NER).

NR1I3_MOUSE
θ value	1.80466e-16 (rank : 59)	NC score	0.870829 (rank : 41)
Query Neighborhood Hits	163	Target Neighborhood Hits	103	Shared Neighborhood Hits	96
SwissProt Accessions	O35627, O35628	Gene names	Nr1i3, Car
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Orphan nuclear receptor MB67).

RORB_HUMAN
θ value	1.80466e-16 (rank : 60)	NC score	0.841881 (rank : 72)
Query Neighborhood Hits	163	Target Neighborhood Hits	99	Shared Neighborhood Hits	94
SwissProt Accessions	Q92753, Q8WX73	Gene names	RORB, NR1F2, RZRB
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

RORB_MOUSE
θ value	1.80466e-16 (rank : 61)	NC score	0.842115 (rank : 71)
Query Neighborhood Hits	163	Target Neighborhood Hits	99	Shared Neighborhood Hits	94
SwissProt Accessions	Q8R1B8	Gene names	Rorb, Nr1f2
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

TR2_MOUSE
θ value	1.80466e-16 (rank : 62)	NC score	0.845241 (rank : 68)
Query Neighborhood Hits	163	Target Neighborhood Hits	100	Shared Neighborhood Hits	96
SwissProt Accessions	Q505F1, P97763, Q3UIJ7, Q4U1Z4, Q60927, Q62152, Q8VIJ3	Gene names	Nr2c1, Tr2, Tr2-11
Domain Architecture	No domain graphic available
Description	Orphan nuclear receptor TR2 (Testicular receptor 2) (mTR2).

RORA_HUMAN
θ value	2.35696e-16 (rank : 63)	NC score	0.841708 (rank : 74)
Query Neighborhood Hits	163	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P35398, P35397, P35399, P45445, Q96H83	Gene names	RORA, NR1F1, RZRA
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

RORA_MOUSE
θ value	2.35696e-16 (rank : 64)	NC score	0.840181 (rank : 78)
Query Neighborhood Hits	163	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P51448, P70283, P97741, P97773, Q923G1	Gene names	Rora, Nr1f1, Rzra
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

TR2_HUMAN
θ value	3.07829e-16 (rank : 65)	NC score	0.857421 (rank : 64)
Query Neighborhood Hits	163	Target Neighborhood Hits	110	Shared Neighborhood Hits	95
SwissProt Accessions	P13056	Gene names	NR2C1, TR2
Domain Architecture
Description	Orphan nuclear receptor TR2 (Testicular receptor 2).

RXRB_HUMAN
θ value	4.02038e-16 (rank : 66)	NC score	0.870384 (rank : 44)
Query Neighborhood Hits	163	Target Neighborhood Hits	280	Shared Neighborhood Hits	108
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

THA_MOUSE
θ value	5.25075e-16 (rank : 67)	NC score	0.839781 (rank : 80)
Query Neighborhood Hits	163	Target Neighborhood Hits	113	Shared Neighborhood Hits	96
SwissProt Accessions	P63058, P10685, P15827, P16416, P37241, Q63107, Q63195, Q63196, Q99146	Gene names	Thra, C-erba-alpha, Nr1a1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1).

THA_HUMAN
θ value	6.85773e-16 (rank : 68)	NC score	0.840014 (rank : 79)
Query Neighborhood Hits	163	Target Neighborhood Hits	113	Shared Neighborhood Hits	96
SwissProt Accessions	P10827, P21205, Q8N6A1, Q96H73	Gene names	THRA, ERBA1, NR1A1, THRA1
Domain Architecture
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1) (EAR-7) (EAR7).

RXRB_MOUSE
θ value	8.95645e-16 (rank : 69)	NC score	0.871935 (rank : 37)
Query Neighborhood Hits	163	Target Neighborhood Hits	230	Shared Neighborhood Hits	106
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

NR1H4_MOUSE
θ value	1.16975e-15 (rank : 70)	NC score	0.866209 (rank : 51)
Query Neighborhood Hits	163	Target Neighborhood Hits	113	Shared Neighborhood Hits	96
SwissProt Accessions	Q60641, Q60642, Q60643	Gene names	Nr1h4, Bar, Fxr, Rip14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

NR6A1_HUMAN
θ value	1.16975e-15 (rank : 71)	NC score	0.867344 (rank : 49)
Query Neighborhood Hits	163	Target Neighborhood Hits	108	Shared Neighborhood Hits	96
SwissProt Accessions	Q15406, O00551, O00603, Q8NHQ0, Q92898, Q99802	Gene names	NR6A1, GCNF
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

PXR_MOUSE
θ value	1.16975e-15 (rank : 72)	NC score	0.845950 (rank : 67)
Query Neighborhood Hits	163	Target Neighborhood Hits	107	Shared Neighborhood Hits	96
SwissProt Accessions	O54915	Gene names	Nr1i2, Pxr
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor).

TR4_HUMAN
θ value	1.99529e-15 (rank : 73)	NC score	0.841737 (rank : 73)
Query Neighborhood Hits	163	Target Neighborhood Hits	117	Shared Neighborhood Hits	96
SwissProt Accessions	P49116, P55092	Gene names	NR2C2, TAK1, TR4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

TR4_MOUSE
θ value	2.60593e-15 (rank : 74)	NC score	0.841504 (rank : 76)
Query Neighborhood Hits	163	Target Neighborhood Hits	115	Shared Neighborhood Hits	96
SwissProt Accessions	P49117, P55093	Gene names	Nr2c2, Mtr2r1, Tak1, Tr4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

NR6A1_MOUSE
θ value	4.44505e-15 (rank : 75)	NC score	0.866034 (rank : 52)
Query Neighborhood Hits	163	Target Neighborhood Hits	110	Shared Neighborhood Hits	96
SwissProt Accessions	Q64249	Gene names	Nr6a1, Gcnf
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

PXR_HUMAN
θ value	4.44505e-15 (rank : 76)	NC score	0.839419 (rank : 81)
Query Neighborhood Hits	163	Target Neighborhood Hits	107	Shared Neighborhood Hits	96
SwissProt Accessions	O75469, Q96AC7, Q9UJ22, Q9UJ23, Q9UJ24, Q9UJ25, Q9UJ26, Q9UJ27	Gene names	NR1I2, PXR
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor) (Orphan nuclear receptor PAR1) (Steroid and xenobiotic receptor) (SXR).

RORG_MOUSE
θ value	4.44505e-15 (rank : 77)	NC score	0.840383 (rank : 77)
Query Neighborhood Hits	163	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	P51450, Q61027, Q91YT5, Q9QXD9, Q9R177	Gene names	Rorc, Nr1f3, Rorg, Thor
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma) (Thymus orphan receptor) (TOR).

RORG_HUMAN
θ value	5.8054e-15 (rank : 78)	NC score	0.835503 (rank : 82)
Query Neighborhood Hits	163	Target Neighborhood Hits	119	Shared Neighborhood Hits	96
SwissProt Accessions	P51449, Q8N5V7, Q8NCY8	Gene names	RORC, NR1F3, RORG, RZRG
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma).

THB2_HUMAN
θ value	9.90251e-15 (rank : 79)	NC score	0.830999 (rank : 85)
Query Neighborhood Hits	163	Target Neighborhood Hits	104	Shared Neighborhood Hits	96
SwissProt Accessions	P37243	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor beta-2.

NR2E3_HUMAN
θ value	2.88119e-14 (rank : 80)	NC score	0.874824 (rank : 30)
Query Neighborhood Hits	163	Target Neighborhood Hits	102	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y5X4, Q9UHM4	Gene names	NR2E3, PNR, RNR
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

PPARG_HUMAN
θ value	4.91457e-14 (rank : 81)	NC score	0.825790 (rank : 90)
Query Neighborhood Hits	163	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37231, O00684, O00710, O14515, Q15178, Q15179, Q15180, Q15832, Q86U60, Q96J12	Gene names	PPARG, NR1C3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

PPARG_MOUSE
θ value	4.91457e-14 (rank : 82)	NC score	0.824731 (rank : 92)
Query Neighborhood Hits	163	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37238	Gene names	Pparg, Nr1c3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

VDR_HUMAN
θ value	1.09485e-13 (rank : 83)	NC score	0.841544 (rank : 75)
Query Neighborhood Hits	163	Target Neighborhood Hits	112	Shared Neighborhood Hits	95
SwissProt Accessions	P11473	Gene names	VDR, NR1I1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

VDR_MOUSE
θ value	1.09485e-13 (rank : 84)	NC score	0.843201 (rank : 69)
Query Neighborhood Hits	163	Target Neighborhood Hits	103	Shared Neighborhood Hits	95
SwissProt Accessions	P48281	Gene names	Vdr, Nr1i1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

THB1_MOUSE
θ value	5.43371e-13 (rank : 85)	NC score	0.827724 (rank : 88)
Query Neighborhood Hits	163	Target Neighborhood Hits	105	Shared Neighborhood Hits	96
SwissProt Accessions	P37242	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-1.

THB2_MOUSE
θ value	5.43371e-13 (rank : 86)	NC score	0.828190 (rank : 86)
Query Neighborhood Hits	163	Target Neighborhood Hits	106	Shared Neighborhood Hits	96
SwissProt Accessions	P37244	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-2.

THB1_HUMAN
θ value	7.09661e-13 (rank : 87)	NC score	0.827931 (rank : 87)
Query Neighborhood Hits	163	Target Neighborhood Hits	106	Shared Neighborhood Hits	96
SwissProt Accessions	P10828, Q13986	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture
Description	Thyroid hormone receptor beta-1.

NR1D1_HUMAN
θ value	6.00763e-12 (rank : 88)	NC score	0.842440 (rank : 70)
Query Neighborhood Hits	163	Target Neighborhood Hits	140	Shared Neighborhood Hits	96
SwissProt Accessions	P20393, Q15304	Gene names	NR1D1, EAR1, HREV, THRAL
Domain Architecture
Description	Orphan nuclear receptor NR1D1 (V-erbA-related protein EAR-1) (Rev- erbA-alpha).

NR1D2_HUMAN
θ value	1.33837e-11 (rank : 89)	NC score	0.833577 (rank : 83)
Query Neighborhood Hits	163	Target Neighborhood Hits	115	Shared Neighborhood Hits	94
SwissProt Accessions	Q14995, O00402, Q86XD4	Gene names	NR1D2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (EAR-1R) (Orphan nuclear hormone receptor BD73).

NR1D2_MOUSE
θ value	1.33837e-11 (rank : 90)	NC score	0.831294 (rank : 84)
Query Neighborhood Hits	163	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	Q60674, Q60646	Gene names	Nr1d2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (Orphan nuclear receptor RVR).

PPARA_MOUSE
θ value	2.98157e-11 (rank : 91)	NC score	0.825211 (rank : 91)
Query Neighborhood Hits	163	Target Neighborhood Hits	99	Shared Neighborhood Hits	95
SwissProt Accessions	P23204	Gene names	Ppara, Nr1c1, Ppar
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

PPARA_HUMAN
θ value	3.89403e-11 (rank : 92)	NC score	0.825954 (rank : 89)
Query Neighborhood Hits	163	Target Neighborhood Hits	100	Shared Neighborhood Hits	94
SwissProt Accessions	Q07869, Q16241, Q92486, Q92689, Q9Y3N1	Gene names	PPARA, NR1C1, PPAR
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

PPARD_HUMAN
θ value	3.89403e-11 (rank : 93)	NC score	0.820020 (rank : 93)
Query Neighborhood Hits	163	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q03181, Q7Z5K0, Q9BUD4	Gene names	PPARD, NR1C2, PPARB
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1) (NUCI).

PPARD_MOUSE
θ value	5.08577e-11 (rank : 94)	NC score	0.816935 (rank : 94)
Query Neighborhood Hits	163	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	P35396, P37239	Gene names	Ppard, Nr1c2, Pparb
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1).

MAGE1_HUMAN
θ value	0.00298849 (rank : 95)	NC score	0.022787 (rank : 101)
Query Neighborhood Hits	163	Target Neighborhood Hits	1389	Shared Neighborhood Hits	43
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

BRCA1_MOUSE
θ value	0.0330416 (rank : 96)	NC score	0.017176 (rank : 108)
Query Neighborhood Hits	163	Target Neighborhood Hits	436	Shared Neighborhood Hits	6
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

OGFR_HUMAN
θ value	0.0563607 (rank : 97)	NC score	0.020021 (rank : 105)
Query Neighborhood Hits	163	Target Neighborhood Hits	1582	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

GA2L1_MOUSE
θ value	0.0961366 (rank : 98)	NC score	0.020715 (rank : 104)
Query Neighborhood Hits	163	Target Neighborhood Hits	114	Shared Neighborhood Hits	8
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

JPH2_HUMAN
θ value	0.0961366 (rank : 99)	NC score	0.013614 (rank : 112)
Query Neighborhood Hits	163	Target Neighborhood Hits	639	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

NACAM_MOUSE
θ value	0.163984 (rank : 100)	NC score	0.028188 (rank : 99)
Query Neighborhood Hits	163	Target Neighborhood Hits	1866	Shared Neighborhood Hits	45
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

DAB1_MOUSE
θ value	0.21417 (rank : 101)	NC score	0.020986 (rank : 103)
Query Neighborhood Hits	163	Target Neighborhood Hits	145	Shared Neighborhood Hits	8
SwissProt Accessions	P97318, P97316, P97317	Gene names	Dab1
Domain Architecture
Description	Disabled homolog 1.

DNM3A_HUMAN
θ value	0.21417 (rank : 102)	NC score	0.017967 (rank : 107)
Query Neighborhood Hits	163	Target Neighborhood Hits	104	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y6K1, Q8WXU9	Gene names	DNMT3A
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA).

GNAS1_HUMAN
θ value	0.21417 (rank : 103)	NC score	0.009143 (rank : 127)
Query Neighborhood Hits	163	Target Neighborhood Hits	278	Shared Neighborhood Hits	16
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

CENG1_HUMAN
θ value	0.47712 (rank : 104)	NC score	0.005180 (rank : 144)
Query Neighborhood Hits	163	Target Neighborhood Hits	544	Shared Neighborhood Hits	13
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

TRIP6_HUMAN
θ value	0.47712 (rank : 105)	NC score	0.006210 (rank : 139)
Query Neighborhood Hits	163	Target Neighborhood Hits	228	Shared Neighborhood Hits	4
SwissProt Accessions	Q15654, O15170, O15275, Q9BTB2, Q9UNT4	Gene names	TRIP6, OIP1
Domain Architecture
Description	Thyroid receptor-interacting protein 6 (TRIP6) (OPA-interacting protein 1) (Zyxin-related protein 1) (ZRP-1).

ZN516_HUMAN
θ value	0.47712 (rank : 106)	NC score	-0.002523 (rank : 158)
Query Neighborhood Hits	163	Target Neighborhood Hits	854	Shared Neighborhood Hits	11
SwissProt Accessions	Q92618	Gene names	ZNF516, KIAA0222
Domain Architecture	No domain graphic available
Description	Zinc finger protein 516.

ENAH_MOUSE
θ value	0.62314 (rank : 107)	NC score	0.013384 (rank : 113)
Query Neighborhood Hits	163	Target Neighborhood Hits	919	Shared Neighborhood Hits	22
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

C1QR1_HUMAN
θ value	0.813845 (rank : 108)	NC score	0.000698 (rank : 154)
Query Neighborhood Hits	163	Target Neighborhood Hits	493	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

DOT1L_HUMAN
θ value	0.813845 (rank : 109)	NC score	0.023662 (rank : 100)
Query Neighborhood Hits	163	Target Neighborhood Hits	660	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

FA13C_HUMAN
θ value	0.813845 (rank : 110)	NC score	0.012952 (rank : 115)
Query Neighborhood Hits	163	Target Neighborhood Hits	94	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

RFIP4_HUMAN
θ value	0.813845 (rank : 111)	NC score	0.000814 (rank : 153)
Query Neighborhood Hits	163	Target Neighborhood Hits	785	Shared Neighborhood Hits	6
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

HNF1A_HUMAN
θ value	1.06291 (rank : 112)	NC score	0.016039 (rank : 110)
Query Neighborhood Hits	163	Target Neighborhood Hits	193	Shared Neighborhood Hits	11
SwissProt Accessions	P20823, Q99861	Gene names	TCF1, HNF1A
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1) (Transcription factor 1) (TCF-1).

PP2CG_HUMAN
θ value	1.06291 (rank : 113)	NC score	0.009827 (rank : 123)
Query Neighborhood Hits	163	Target Neighborhood Hits	140	Shared Neighborhood Hits	4
SwissProt Accessions	O15355	Gene names	PPM1G, PPM1C
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C).

FGD3_HUMAN
θ value	1.38821 (rank : 114)	NC score	0.002667 (rank : 148)
Query Neighborhood Hits	163	Target Neighborhood Hits	249	Shared Neighborhood Hits	4
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

CDC2_HUMAN
θ value	1.81305 (rank : 115)	NC score	-0.006216 (rank : 164)
Query Neighborhood Hits	163	Target Neighborhood Hits	842	Shared Neighborhood Hits	5
SwissProt Accessions	P06493, O60764	Gene names	CDC2
Domain Architecture
Description	Cell division control protein 2 homolog (EC 2.7.11.22) (EC 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1).

CDC2_MOUSE
θ value	1.81305 (rank : 116)	NC score	-0.006179 (rank : 163)
Query Neighborhood Hits	163	Target Neighborhood Hits	838	Shared Neighborhood Hits	5
SwissProt Accessions	P11440, P70337, Q3TI12	Gene names	Cdc2, Cdc2a
Domain Architecture
Description	Cell division control protein 2 homolog (EC 2.7.11.22) (EC 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1).

NCOA6_MOUSE
θ value	1.81305 (rank : 117)	NC score	0.021445 (rank : 102)
Query Neighborhood Hits	163	Target Neighborhood Hits	1076	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

TULP4_HUMAN
θ value	1.81305 (rank : 118)	NC score	0.008795 (rank : 130)
Query Neighborhood Hits	163	Target Neighborhood Hits	426	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

BSN_MOUSE
θ value	2.36792 (rank : 119)	NC score	0.012549 (rank : 117)
Query Neighborhood Hits	163	Target Neighborhood Hits	2057	Shared Neighborhood Hits	45
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CMTA2_MOUSE
θ value	2.36792 (rank : 120)	NC score	0.008928 (rank : 129)
Query Neighborhood Hits	163	Target Neighborhood Hits	216	Shared Neighborhood Hits	10
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

DAX1_HUMAN
θ value	2.36792 (rank : 121)	NC score	0.380036 (rank : 98)
Query Neighborhood Hits	163	Target Neighborhood Hits	65	Shared Neighborhood Hits	57
SwissProt Accessions	P51843, Q96F69	Gene names	NR0B1, AHC, DAX1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1) (DSS-AHC critical region on the X chromosome protein 1).

PAPOG_MOUSE
θ value	2.36792 (rank : 122)	NC score	0.006296 (rank : 137)
Query Neighborhood Hits	163	Target Neighborhood Hits	103	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PCL9, Q8BZC9	Gene names	Papolg
Domain Architecture	No domain graphic available
Description	Poly(A) polymerase gamma (EC 2.7.7.19) (PAP gamma) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3' adenylating enzyme).

RTN1_HUMAN
θ value	2.36792 (rank : 123)	NC score	0.009003 (rank : 128)
Query Neighborhood Hits	163	Target Neighborhood Hits	173	Shared Neighborhood Hits	9
SwissProt Accessions	Q16799, Q16800, Q16801	Gene names	RTN1, NSP
Domain Architecture
Description	Reticulon-1 (Neuroendocrine-specific protein).

SHP_HUMAN
θ value	2.36792 (rank : 124)	NC score	0.410300 (rank : 95)
Query Neighborhood Hits	163	Target Neighborhood Hits	57	Shared Neighborhood Hits	54
SwissProt Accessions	Q15466, Q5QP36	Gene names	NR0B2, SHP
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

DAB1_HUMAN
θ value	3.0926 (rank : 125)	NC score	0.016322 (rank : 109)
Query Neighborhood Hits	163	Target Neighborhood Hits	219	Shared Neighborhood Hits	13
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

KCNH2_MOUSE
θ value	3.0926 (rank : 126)	NC score	0.003471 (rank : 146)
Query Neighborhood Hits	163	Target Neighborhood Hits	165	Shared Neighborhood Hits	11
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KIF22_HUMAN
θ value	3.0926 (rank : 127)	NC score	0.001114 (rank : 152)
Query Neighborhood Hits	163	Target Neighborhood Hits	110	Shared Neighborhood Hits	2
SwissProt Accessions	Q14807, O94814, Q9BT46	Gene names	KIF22, KID, KNSL4
Domain Architecture
Description	Kinesin-like protein KIF22 (Kinesin-like DNA-binding protein) (Kinesin-like protein 4).

NEIL1_HUMAN
θ value	3.0926 (rank : 128)	NC score	0.010581 (rank : 119)
Query Neighborhood Hits	163	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q96FI4, Q6ZRA7, Q86XW7, Q9H6C3	Gene names	NEIL1
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 1 (EC 3.2.2.-) (EC 4.2.99.18) (Nei-like 1) (DNA glycosylase/AP lyase Neil1) (DNA-(apurinic or apyrimidinic site) lyase Neil1) (NEH1) (FPG1).

SON_HUMAN
θ value	3.0926 (rank : 129)	NC score	0.009255 (rank : 124)
Query Neighborhood Hits	163	Target Neighborhood Hits	1568	Shared Neighborhood Hits	37
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

DNM3A_MOUSE
θ value	4.03905 (rank : 130)	NC score	0.012591 (rank : 116)
Query Neighborhood Hits	163	Target Neighborhood Hits	91	Shared Neighborhood Hits	4
SwissProt Accessions	O88508, Q3UH24, Q8CJ60, Q922J0, Q9CSE1	Gene names	Dnmt3a
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA).

HNF1A_MOUSE
θ value	4.03905 (rank : 131)	NC score	0.013297 (rank : 114)
Query Neighborhood Hits	163	Target Neighborhood Hits	212	Shared Neighborhood Hits	13
SwissProt Accessions	P22361	Gene names	Tcf1, Hnf-1, Hnf-1a, Hnf1a
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1).

MKL1_MOUSE
θ value	4.03905 (rank : 132)	NC score	0.010720 (rank : 118)
Query Neighborhood Hits	163	Target Neighborhood Hits	667	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

NCOA6_HUMAN
θ value	4.03905 (rank : 133)	NC score	0.018418 (rank : 106)
Query Neighborhood Hits	163	Target Neighborhood Hits	1202	Shared Neighborhood Hits	39
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

RUNX1_HUMAN
θ value	4.03905 (rank : 134)	NC score	0.004961 (rank : 145)
Query Neighborhood Hits	163	Target Neighborhood Hits	94	Shared Neighborhood Hits	3
SwissProt Accessions	Q01196, O60472, O60473, O76047, O76089, Q13081, Q13755, Q13756, Q13757, Q13758, Q13759, Q15341, Q15343, Q16122, Q16284, Q16285, Q16286, Q16346, Q16347, Q92479	Gene names	RUNX1, AML1, CBFA2
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

SDC3_HUMAN
θ value	4.03905 (rank : 135)	NC score	0.014011 (rank : 111)
Query Neighborhood Hits	163	Target Neighborhood Hits	103	Shared Neighborhood Hits	8
SwissProt Accessions	O75056, Q5T1Z6, Q5T1Z7, Q96CT3, Q96PR8	Gene names	SDC3, KIAA0468
Domain Architecture
Description	Syndecan-3 (SYND3).

SSPO_MOUSE
θ value	4.03905 (rank : 136)	NC score	-0.002549 (rank : 159)
Query Neighborhood Hits	163	Target Neighborhood Hits	800	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

TISB_HUMAN
θ value	4.03905 (rank : 137)	NC score	0.010279 (rank : 121)
Query Neighborhood Hits	163	Target Neighborhood Hits	56	Shared Neighborhood Hits	6
SwissProt Accessions	Q07352, Q13851	Gene names	ZFP36L1, BERG36, BRF1, ERF1, TIS11B
Domain Architecture
Description	Butyrate response factor 1 (TIS11B protein) (EGF-response factor 1) (ERF-1).

TISB_MOUSE
θ value	4.03905 (rank : 138)	NC score	0.010303 (rank : 120)
Query Neighborhood Hits	163	Target Neighborhood Hits	56	Shared Neighborhood Hits	6
SwissProt Accessions	P23950	Gene names	Zfp36l1, Brf1, Tis11b
Domain Architecture
Description	Butyrate response factor 1 (TIS11B protein).

ZN516_MOUSE
θ value	4.03905 (rank : 139)	NC score	-0.002784 (rank : 160)
Query Neighborhood Hits	163	Target Neighborhood Hits	1197	Shared Neighborhood Hits	25
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

DMRTD_MOUSE
θ value	5.27518 (rank : 140)	NC score	0.005963 (rank : 140)
Query Neighborhood Hits	163	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CGW9	Gene names	Dmrtc2, Dmrt7
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2 (Doublesex- and mab-3-related transcription factor 7).

JIP2_HUMAN
θ value	5.27518 (rank : 141)	NC score	0.006962 (rank : 135)
Query Neighborhood Hits	163	Target Neighborhood Hits	288	Shared Neighborhood Hits	11
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

K0056_HUMAN
θ value	5.27518 (rank : 142)	NC score	0.009164 (rank : 126)
Query Neighborhood Hits	163	Target Neighborhood Hits	107	Shared Neighborhood Hits	4
SwissProt Accessions	P42695	Gene names	KIAA0056
Domain Architecture	No domain graphic available
Description	Protein KIAA0056.

NBR1_HUMAN
θ value	5.27518 (rank : 143)	NC score	0.006231 (rank : 138)
Query Neighborhood Hits	163	Target Neighborhood Hits	105	Shared Neighborhood Hits	2
SwissProt Accessions	Q14596, Q13173, Q15026, Q96GB6, Q9NRF7	Gene names	NBR1, 1A13B, KIAA0049, M17S2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2) (1A1-3B).

SUSD4_MOUSE
θ value	5.27518 (rank : 144)	NC score	0.007987 (rank : 134)
Query Neighborhood Hits	163	Target Neighborhood Hits	122	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

CILP2_HUMAN
θ value	6.88961 (rank : 145)	NC score	0.000409 (rank : 155)
Query Neighborhood Hits	163	Target Neighborhood Hits	307	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

CLN5_HUMAN
θ value	6.88961 (rank : 146)	NC score	0.009997 (rank : 122)
Query Neighborhood Hits	163	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	O75503	Gene names	CLN5
Domain Architecture	No domain graphic available
Description	Ceroid-lipofuscinosis neuronal protein 5 (Protein CLN5).

GNAS1_MOUSE
θ value	6.88961 (rank : 147)	NC score	0.008401 (rank : 131)
Query Neighborhood Hits	163	Target Neighborhood Hits	651	Shared Neighborhood Hits	20
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

IP3KB_HUMAN
θ value	6.88961 (rank : 148)	NC score	0.005846 (rank : 142)
Query Neighborhood Hits	163	Target Neighborhood Hits	124	Shared Neighborhood Hits	7
SwissProt Accessions	P27987, Q5VWL9, Q5VWM0, Q96BZ2, Q96JS1, Q9UH47	Gene names	ITPKB
Domain Architecture
Description	Inositol-trisphosphate 3-kinase B (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase B) (IP3K B) (IP3 3-kinase B) (IP3K-B).

SHAN1_HUMAN
θ value	6.88961 (rank : 149)	NC score	0.002640 (rank : 149)
Query Neighborhood Hits	163	Target Neighborhood Hits	1041	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

TBCD4_MOUSE
θ value	6.88961 (rank : 150)	NC score	0.001365 (rank : 151)
Query Neighborhood Hits	163	Target Neighborhood Hits	276	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BYJ6, Q5DU23, Q66JU2, Q6P2M2, Q8BMH6, Q8BXM2	Gene names	Tbc1d4, Kiaa0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

XKR6_HUMAN
θ value	6.88961 (rank : 151)	NC score	0.003212 (rank : 147)
Query Neighborhood Hits	163	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q5GH73, Q8TBA0	Gene names	XKR6, C8orf21, C8orf7, XRG6
Domain Architecture	No domain graphic available
Description	XK-related protein 6.

BAT3_MOUSE
θ value	8.99809 (rank : 152)	NC score	0.009206 (rank : 125)
Query Neighborhood Hits	163	Target Neighborhood Hits	518	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

BTBDC_HUMAN
θ value	8.99809 (rank : 153)	NC score	0.005313 (rank : 143)
Query Neighborhood Hits	163	Target Neighborhood Hits	248	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

CI040_MOUSE
θ value	8.99809 (rank : 154)	NC score	0.008037 (rank : 133)
Query Neighborhood Hits	163	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VCE4, Q8BJJ5	Gene names
Domain Architecture	No domain graphic available
Description	Protein C9orf40 homolog.

DREB_MOUSE
θ value	8.99809 (rank : 155)	NC score	0.001962 (rank : 150)
Query Neighborhood Hits	163	Target Neighborhood Hits	446	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

F100B_HUMAN
θ value	8.99809 (rank : 156)	NC score	0.006480 (rank : 136)
Query Neighborhood Hits	163	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IYN6	Gene names	FAM100B
Domain Architecture	No domain graphic available
Description	Protein FAM100B.

FOG1_MOUSE
θ value	8.99809 (rank : 157)	NC score	-0.004972 (rank : 161)
Query Neighborhood Hits	163	Target Neighborhood Hits	1237	Shared Neighborhood Hits	22
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

HAX1_MOUSE
θ value	8.99809 (rank : 158)	NC score	0.005922 (rank : 141)
Query Neighborhood Hits	163	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	O35387	Gene names	Hax1, Hs1bp1
Domain Architecture	No domain graphic available
Description	HS1-associating protein X-1 (HAX-1) (HS1-binding protein).

K1949_MOUSE
θ value	8.99809 (rank : 159)	NC score	0.008127 (rank : 132)
Query Neighborhood Hits	163	Target Neighborhood Hits	134	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BQ30, Q3UDS6, Q8CEY9, Q8R3D8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1949 homolog.

MK07_MOUSE
θ value	8.99809 (rank : 160)	NC score	-0.006742 (rank : 165)
Query Neighborhood Hits	163	Target Neighborhood Hits	1054	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

POGZ_HUMAN
θ value	8.99809 (rank : 161)	NC score	-0.005528 (rank : 162)
Query Neighborhood Hits	163	Target Neighborhood Hits	745	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z3K3, O75049, Q8TDZ7, Q9Y4X7	Gene names	POGZ, KIAA0461
Domain Architecture
Description	Pogo transposable element with ZNF domain.

RIMB1_HUMAN
θ value	8.99809 (rank : 162)	NC score	-0.001033 (rank : 156)
Query Neighborhood Hits	163	Target Neighborhood Hits	1479	Shared Neighborhood Hits	21
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

WDR33_HUMAN
θ value	8.99809 (rank : 163)	NC score	-0.002053 (rank : 157)
Query Neighborhood Hits	163	Target Neighborhood Hits	638	Shared Neighborhood Hits	14
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

DAX1_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.399195 (rank : 97)
Query Neighborhood Hits	163	Target Neighborhood Hits	70	Shared Neighborhood Hits	58
SwissProt Accessions	Q61066, O09068, O09147	Gene names	Nr0b1, Ahch, Dax1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1).

SHP_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.406346 (rank : 96)
Query Neighborhood Hits	163	Target Neighborhood Hits	53	Shared Neighborhood Hits	51
SwissProt Accessions	Q62227, Q53Z53	Gene names	Nr0b2, Shp
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

Hits sorted by NC score

PRGR_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	163	Target Neighborhood Hits	163	Shared Neighborhood Hits	163
SwissProt Accessions	P06401, Q9UPF7	Gene names	PGR, NR3C3
Domain Architecture
Description	Progesterone receptor (PR).

PRGR_MOUSE
NC score	0.987492 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	163	Target Neighborhood Hits	286	Shared Neighborhood Hits	106
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

GCR_HUMAN
NC score	0.981583 (rank : 3)	θ value	5.63297e-119 (rank : 7)
Query Neighborhood Hits	163	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P04150, P04151, Q53EP5, Q6N0A4	Gene names	NR3C1, GRL
Domain Architecture
Description	Glucocorticoid receptor (GR).

ANDR_HUMAN
NC score	0.981228 (rank : 4)	θ value	6.01832e-121 (rank : 5)
Query Neighborhood Hits	163	Target Neighborhood Hits	126	Shared Neighborhood Hits	97
SwissProt Accessions	P10275	Gene names	AR, DHTR, NR3C4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

GCR_MOUSE
NC score	0.981169 (rank : 5)	θ value	1.48236e-119 (rank : 6)
Query Neighborhood Hits	163	Target Neighborhood Hits	117	Shared Neighborhood Hits	95
SwissProt Accessions	P06537, Q61628, Q61629	Gene names	Nr3c1, Grl, Grl1
Domain Architecture
Description	Glucocorticoid receptor (GR).

ANDR_MOUSE
NC score	0.980031 (rank : 6)	θ value	9.92011e-124 (rank : 3)
Query Neighborhood Hits	163	Target Neighborhood Hits	133	Shared Neighborhood Hits	95
SwissProt Accessions	P19091	Gene names	Ar, Nr3c4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

MCR_HUMAN
NC score	0.977066 (rank : 7)	θ value	1.21265e-121 (rank : 4)
Query Neighborhood Hits	163	Target Neighborhood Hits	149	Shared Neighborhood Hits	97
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

MCR_MOUSE
NC score	0.975826 (rank : 8)	θ value	1.43579e-114 (rank : 8)
Query Neighborhood Hits	163	Target Neighborhood Hits	162	Shared Neighborhood Hits	99
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

ESR1_MOUSE
NC score	0.934242 (rank : 9)	θ value	1.3722e-40 (rank : 15)
Query Neighborhood Hits	163	Target Neighborhood Hits	104	Shared Neighborhood Hits	94
SwissProt Accessions	P19785, Q9JJT5, Q9QY51, Q9QY52	Gene names	Esr1, Esr, Estr, Estra, Nr3a1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

ESR1_HUMAN
NC score	0.932994 (rank : 10)	θ value	3.05695e-40 (rank : 16)
Query Neighborhood Hits	163	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P03372, Q13511, Q14276, Q9NU51, Q9UDZ7, Q9UIS7	Gene names	ESR1, ESR, NR3A1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

ESR2_MOUSE
NC score	0.932818 (rank : 11)	θ value	6.15952e-41 (rank : 14)
Query Neighborhood Hits	163	Target Neighborhood Hits	110	Shared Neighborhood Hits	96
SwissProt Accessions	O08537, O35635, O70519	Gene names	Esr2, Estrb, Nr3a2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

ESR2_HUMAN
NC score	0.932677 (rank : 12)	θ value	7.27602e-42 (rank : 13)
Query Neighborhood Hits	163	Target Neighborhood Hits	110	Shared Neighborhood Hits	96
SwissProt Accessions	Q92731, O60608, O60685, O60702, O60703, O75583, O75584, Q86Z31, Q9UEV6, Q9UHD3, Q9UQK9	Gene names	ESR2, ESTRB, NR3A2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

ERR1_HUMAN
NC score	0.929637 (rank : 13)	θ value	8.89434e-40 (rank : 17)
Query Neighborhood Hits	163	Target Neighborhood Hits	157	Shared Neighborhood Hits	99
SwissProt Accessions	P11474, Q14514	Gene names	ESRRA, ERR1, ESRL1, NR3B1
Domain Architecture
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR- alpha) (Estrogen receptor-like 1).

ERR2_HUMAN
NC score	0.927265 (rank : 14)	θ value	1.19932e-44 (rank : 9)
Query Neighborhood Hits	163	Target Neighborhood Hits	108	Shared Neighborhood Hits	96
SwissProt Accessions	O95718, Q9HCB4	Gene names	ESRRB, ERRB2, NR3B2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2) (ERR beta-2).

ERR2_MOUSE
NC score	0.926740 (rank : 15)	θ value	4.55743e-44 (rank : 10)
Query Neighborhood Hits	163	Target Neighborhood Hits	109	Shared Neighborhood Hits	96
SwissProt Accessions	Q61539, O09067, O09146	Gene names	Esrrb, Err-2, Err2, Nr3b2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2).

ERR3_HUMAN
NC score	0.924478 (rank : 16)	θ value	5.95217e-44 (rank : 11)
Query Neighborhood Hits	163	Target Neighborhood Hits	106	Shared Neighborhood Hits	96
SwissProt Accessions	P62508, O75454, O96021, Q68DA0, Q6P274, Q6PK28, Q6TS38, Q9R1F3, Q9UNJ4	Gene names	ESRRG, ERR3, ERRG2, KIAA0832, NR3B3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (ERR gamma-2).

ERR3_MOUSE
NC score	0.924478 (rank : 17)	θ value	5.95217e-44 (rank : 12)
Query Neighborhood Hits	163	Target Neighborhood Hits	106	Shared Neighborhood Hits	96
SwissProt Accessions	P62509, O75454, O96021, Q8CHC9, Q9R1F3	Gene names	Esrrg, Err3, Kiaa0832, Nr3b3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3).

NR2E1_MOUSE
NC score	0.889143 (rank : 18)	θ value	6.84181e-24 (rank : 24)
Query Neighborhood Hits	163	Target Neighborhood Hits	106	Shared Neighborhood Hits	96
SwissProt Accessions	Q64104	Gene names	Nr2e1, Tll, Tlx
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (mTll).

NR2E1_HUMAN
NC score	0.886719 (rank : 19)	θ value	8.36355e-22 (rank : 30)
Query Neighborhood Hits	163	Target Neighborhood Hits	103	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y466	Gene names	NR2E1, TLX
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (hTll).

NR2E3_MOUSE
NC score	0.883904 (rank : 20)	θ value	1.5242e-23 (rank : 26)
Query Neighborhood Hits	163	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	Q9QXZ7	Gene names	Nr2e3, Pnr, Rnr
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

HNF4G_HUMAN
NC score	0.881838 (rank : 21)	θ value	8.08199e-25 (rank : 18)
Query Neighborhood Hits	163	Target Neighborhood Hits	100	Shared Neighborhood Hits	96
SwissProt Accessions	Q14541, Q9UH81, Q9UIS6	Gene names	HNF4G, NR2A2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

HNF4G_MOUSE
NC score	0.881089 (rank : 22)	θ value	5.23862e-24 (rank : 23)
Query Neighborhood Hits	163	Target Neighborhood Hits	101	Shared Neighborhood Hits	96
SwissProt Accessions	Q9WUU6	Gene names	Hnf4g, Nr2a2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

HNF4A_MOUSE
NC score	0.879650 (rank : 23)	θ value	1.16704e-23 (rank : 25)
Query Neighborhood Hits	163	Target Neighborhood Hits	103	Shared Neighborhood Hits	96
SwissProt Accessions	P49698	Gene names	Hnf4a, Hnf-4, Hnf4, Nr2a1, Tcf14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

HNF4A_HUMAN
NC score	0.877972 (rank : 24)	θ value	2.20094e-22 (rank : 29)
Query Neighborhood Hits	163	Target Neighborhood Hits	105	Shared Neighborhood Hits	96
SwissProt Accessions	P41235, O00659, O00723, Q14540, Q92653, Q92654, Q92655, Q99864, Q9NQH0	Gene names	HNF4A, HNF4, NR2A1, TCF14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

RXRG_MOUSE
NC score	0.877829 (rank : 25)	θ value	4.01107e-24 (rank : 22)
Query Neighborhood Hits	163	Target Neighborhood Hits	113	Shared Neighborhood Hits	96
SwissProt Accessions	P28705	Gene names	Rxrg, Nr2b3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

RXRA_MOUSE
NC score	0.877533 (rank : 26)	θ value	1.80048e-24 (rank : 19)
Query Neighborhood Hits	163	Target Neighborhood Hits	129	Shared Neighborhood Hits	98
SwissProt Accessions	P28700	Gene names	Rxra, Nr2b1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

EAR2_HUMAN
NC score	0.876614 (rank : 27)	θ value	2.20094e-22 (rank : 28)
Query Neighborhood Hits	163	Target Neighborhood Hits	106	Shared Neighborhood Hits	96
SwissProt Accessions	P10588, Q9BUE8	Gene names	NR2F6, EAR2, ERBAL2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

EAR2_MOUSE
NC score	0.876363 (rank : 28)	θ value	2.59989e-23 (rank : 27)
Query Neighborhood Hits	163	Target Neighborhood Hits	104	Shared Neighborhood Hits	96
SwissProt Accessions	P43136, Q61504	Gene names	Nr2f6, Ear-2, Ear2, Erbal2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

RXRG_HUMAN
NC score	0.876089 (rank : 29)	θ value	2.35151e-24 (rank : 21)
Query Neighborhood Hits	163	Target Neighborhood Hits	114	Shared Neighborhood Hits	96
SwissProt Accessions	P48443	Gene names	RXRG, NR2B3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

NR2E3_HUMAN
NC score	0.874824 (rank : 30)	θ value	2.88119e-14 (rank : 80)
Query Neighborhood Hits	163	Target Neighborhood Hits	102	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y5X4, Q9UHM4	Gene names	NR2E3, PNR, RNR
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

RXRA_HUMAN
NC score	0.874716 (rank : 31)	θ value	2.35151e-24 (rank : 20)
Query Neighborhood Hits	163	Target Neighborhood Hits	223	Shared Neighborhood Hits	98
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

NR4A1_HUMAN
NC score	0.873461 (rank : 32)	θ value	3.51386e-20 (rank : 41)
Query Neighborhood Hits	163	Target Neighborhood Hits	133	Shared Neighborhood Hits	97
SwissProt Accessions	P22736	Gene names	NR4A1, GFRP1, HMR, NAK1
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Early response protein NAK1) (TR3 orphan receptor) (ST-59).

NR4A3_HUMAN
NC score	0.873155 (rank : 33)	θ value	2.5182e-18 (rank : 50)
Query Neighborhood Hits	163	Target Neighborhood Hits	131	Shared Neighborhood Hits	100
SwissProt Accessions	Q92570, Q12935, Q14979, Q16420, Q4VXA9, Q9UEK2, Q9UEK3	Gene names	NR4A3, CHN, CSMF, MINOR, NOR1, TEC
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Nuclear hormone receptor NOR-1) (Neuron-derived orphan receptor 1) (Mitogen-induced nuclear orphan receptor).

NR4A1_MOUSE
NC score	0.872771 (rank : 34)	θ value	1.02238e-19 (rank : 44)
Query Neighborhood Hits	163	Target Neighborhood Hits	128	Shared Neighborhood Hits	96
SwissProt Accessions	P12813	Gene names	Nr4a1, Gfrp, Hmr, N10, Nur77
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Nuclear hormone receptor NUR/77) (N10 nuclear protein).

STF1_HUMAN
NC score	0.872297 (rank : 35)	θ value	3.28887e-18 (rank : 52)
Query Neighborhood Hits	163	Target Neighborhood Hits	132	Shared Neighborhood Hits	99
SwissProt Accessions	Q13285, O15196	Gene names	NR5A1, AD4BP, FTZF1, SF1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1).

STF1_MOUSE
NC score	0.871959 (rank : 36)	θ value	3.28887e-18 (rank : 53)
Query Neighborhood Hits	163	Target Neighborhood Hits	137	Shared Neighborhood Hits	98
SwissProt Accessions	P33242	Gene names	Nr5a1, Ftzf1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1) (Embryonal LTR-binding protein) (ELP) (Embryonal long terminal repeat- binding protein) (Steroid hydroxylase positive regulator).

RXRB_MOUSE
NC score	0.871935 (rank : 37)	θ value	8.95645e-16 (rank : 69)
Query Neighborhood Hits	163	Target Neighborhood Hits	230	Shared Neighborhood Hits	106
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

NR4A3_MOUSE
NC score	0.871411 (rank : 38)	θ value	7.32683e-18 (rank : 54)
Query Neighborhood Hits	163	Target Neighborhood Hits	127	Shared Neighborhood Hits	98
SwissProt Accessions	Q9QZB6, Q9QZB5	Gene names	Nr4a3, Tec
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Orphan nuclear receptor TEC) (Translocated in extraskeletal chondrosarcoma).

COT2_HUMAN
NC score	0.870988 (rank : 39)	θ value	2.43343e-21 (rank : 33)
Query Neighborhood Hits	163	Target Neighborhood Hits	135	Shared Neighborhood Hits	98
SwissProt Accessions	P24468, Q03754	Gene names	NR2F2, ARP1, TFCOUP2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

COT2_MOUSE
NC score	0.870988 (rank : 40)	θ value	2.43343e-21 (rank : 34)
Query Neighborhood Hits	163	Target Neighborhood Hits	135	Shared Neighborhood Hits	98
SwissProt Accessions	P43135	Gene names	Nr2f2, Aporp1, Arp-1, Arp1, Tfcoup2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

NR1I3_MOUSE
NC score	0.870829 (rank : 41)	θ value	1.80466e-16 (rank : 59)
Query Neighborhood Hits	163	Target Neighborhood Hits	103	Shared Neighborhood Hits	96
SwissProt Accessions	O35627, O35628	Gene names	Nr1i3, Car
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Orphan nuclear receptor MB67).

NR4A2_HUMAN
NC score	0.870641 (rank : 42)	θ value	8.65492e-19 (rank : 47)
Query Neighborhood Hits	163	Target Neighborhood Hits	120	Shared Neighborhood Hits	96
SwissProt Accessions	P43354, Q16311	Gene names	NR4A2, NOT, NURR1, TINUR
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (Immediate-early response protein NOT) (Transcriptionally-inducible nuclear receptor).

NR4A2_MOUSE
NC score	0.870489 (rank : 43)	θ value	8.65492e-19 (rank : 48)
Query Neighborhood Hits	163	Target Neighborhood Hits	121	Shared Neighborhood Hits	96
SwissProt Accessions	Q06219, O08690	Gene names	Nr4a2, Nurr1
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (NUR- related factor 1).

RXRB_HUMAN
NC score	0.870384 (rank : 44)	θ value	4.02038e-16 (rank : 66)
Query Neighborhood Hits	163	Target Neighborhood Hits	280	Shared Neighborhood Hits	108
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

NR1I3_HUMAN
NC score	0.870252 (rank : 45)	θ value	2.13179e-17 (rank : 56)
Query Neighborhood Hits	163	Target Neighborhood Hits	107	Shared Neighborhood Hits	96
SwissProt Accessions	Q14994	Gene names	NR1I3, CAR
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Constitutive activator of retinoid response) (Constitutive active response) (Orphan nuclear receptor MB67).

COT1_MOUSE
NC score	0.869424 (rank : 46)	θ value	1.86321e-21 (rank : 32)
Query Neighborhood Hits	163	Target Neighborhood Hits	160	Shared Neighborhood Hits	96
SwissProt Accessions	Q60632, Q61438	Gene names	Nr2f1, Erbal3, Tfcoup1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I).

COT1_HUMAN
NC score	0.869138 (rank : 47)	θ value	1.86321e-21 (rank : 31)
Query Neighborhood Hits	163	Target Neighborhood Hits	159	Shared Neighborhood Hits	96
SwissProt Accessions	P10589	Gene names	NR2F1, EAR3, ERBAL3, TFCOUP1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I) (V-ERBA-related protein EAR-3).

NR1H4_HUMAN
NC score	0.869029 (rank : 48)	θ value	3.88503e-19 (rank : 45)
Query Neighborhood Hits	163	Target Neighborhood Hits	112	Shared Neighborhood Hits	96
SwissProt Accessions	Q96RI1, Q8NFP5, Q8NFP6, Q92943	Gene names	NR1H4, BAR, FXR, HRR1, RIP14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

NR6A1_HUMAN
NC score	0.867344 (rank : 49)	θ value	1.16975e-15 (rank : 71)
Query Neighborhood Hits	163	Target Neighborhood Hits	108	Shared Neighborhood Hits	96
SwissProt Accessions	Q15406, O00551, O00603, Q8NHQ0, Q92898, Q99802	Gene names	NR6A1, GCNF
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

NR5A2_MOUSE
NC score	0.866301 (rank : 50)	θ value	5.99374e-20 (rank : 42)
Query Neighborhood Hits	163	Target Neighborhood Hits	107	Shared Neighborhood Hits	96
SwissProt Accessions	P45448	Gene names	Nr5a2, Lrh1
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Liver receptor homolog 1) (LRH-1).

NR1H4_MOUSE
NC score	0.866209 (rank : 51)	θ value	1.16975e-15 (rank : 70)
Query Neighborhood Hits	163	Target Neighborhood Hits	113	Shared Neighborhood Hits	96
SwissProt Accessions	Q60641, Q60642, Q60643	Gene names	Nr1h4, Bar, Fxr, Rip14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

NR6A1_MOUSE
NC score	0.866034 (rank : 52)	θ value	4.44505e-15 (rank : 75)
Query Neighborhood Hits	163	Target Neighborhood Hits	110	Shared Neighborhood Hits	96
SwissProt Accessions	Q64249	Gene names	Nr6a1, Gcnf
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

NR1H3_MOUSE
NC score	0.864437 (rank : 53)	θ value	1.63225e-17 (rank : 55)
Query Neighborhood Hits	163	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Z0Y9, Q9QUH7	Gene names	Nr1h3, Lxra
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

NR1H3_HUMAN
NC score	0.864329 (rank : 54)	θ value	3.28887e-18 (rank : 51)
Query Neighborhood Hits	163	Target Neighborhood Hits	104	Shared Neighborhood Hits	94
SwissProt Accessions	Q13133, Q96H87	Gene names	NR1H3, LXRA
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

RARG1_HUMAN
NC score	0.863394 (rank : 55)	θ value	2.06002e-20 (rank : 37)
Query Neighborhood Hits	163	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	P13631	Gene names	RARG, NR1B3
Domain Architecture
Description	Retinoic acid receptor gamma-1 (RAR-gamma-1).

NR5A2_HUMAN
NC score	0.863333 (rank : 56)	θ value	7.82807e-20 (rank : 43)
Query Neighborhood Hits	163	Target Neighborhood Hits	112	Shared Neighborhood Hits	96
SwissProt Accessions	O00482, O95642	Gene names	NR5A2, B1F, CPF, FTF
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Alpha-1-fetoprotein transcription factor) (Hepatocytic transcription factor) (B1-binding factor) (hB1F) (CYP7A promoter-binding factor) (Liver receptor homolog 1) (LRH-1).

RARG2_HUMAN
NC score	0.863329 (rank : 57)	θ value	2.06002e-20 (rank : 39)
Query Neighborhood Hits	163	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	P22932, Q15281	Gene names	RARG, NR1B3
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor gamma-2 (RAR-gamma-2).

RARG2_MOUSE
NC score	0.863031 (rank : 58)	θ value	2.06002e-20 (rank : 40)
Query Neighborhood Hits	163	Target Neighborhood Hits	114	Shared Neighborhood Hits	94
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

RARG1_MOUSE
NC score	0.862893 (rank : 59)	θ value	2.06002e-20 (rank : 38)
Query Neighborhood Hits	163	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

RARA_HUMAN
NC score	0.860399 (rank : 60)	θ value	5.42112e-21 (rank : 35)
Query Neighborhood Hits	163	Target Neighborhood Hits	118	Shared Neighborhood Hits	96
SwissProt Accessions	P10276, P78456, Q13440, Q13441, Q9NQS0	Gene names	RARA, NR1B1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARA_MOUSE
NC score	0.859886 (rank : 61)	θ value	1.5773e-20 (rank : 36)
Query Neighborhood Hits	163	Target Neighborhood Hits	113	Shared Neighborhood Hits	96
SwissProt Accessions	P11416, P22603	Gene names	Rara, Nr1b1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARB_HUMAN
NC score	0.859377 (rank : 62)	θ value	6.62687e-19 (rank : 46)
Query Neighborhood Hits	163	Target Neighborhood Hits	118	Shared Neighborhood Hits	94
SwissProt Accessions	P10826, P12891, Q00989, Q15298, Q9UN48	Gene names	RARB, HAP, NR1B2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta) (RAR-epsilon) (HBV-activated protein).

RARB_MOUSE
NC score	0.859103 (rank : 63)	θ value	8.65492e-19 (rank : 49)
Query Neighborhood Hits	163	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	P22605, P11417, P22604	Gene names	Rarb, Nr1b2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta).

TR2_HUMAN
NC score	0.857421 (rank : 64)	θ value	3.07829e-16 (rank : 65)
Query Neighborhood Hits	163	Target Neighborhood Hits	110	Shared Neighborhood Hits	95
SwissProt Accessions	P13056	Gene names	NR2C1, TR2
Domain Architecture
Description	Orphan nuclear receptor TR2 (Testicular receptor 2).

NR1H2_MOUSE
NC score	0.857263 (rank : 65)	θ value	8.10077e-17 (rank : 57)
Query Neighborhood Hits	163	Target Neighborhood Hits	109	Shared Neighborhood Hits	97
SwissProt Accessions	Q60644	Gene names	Nr1h2, Lxrb, Rip15, Unr, Unr2
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Retinoid X receptor-interacting protein No.15).

NR1H2_HUMAN
NC score	0.853496 (rank : 66)	θ value	1.38178e-16 (rank : 58)
Query Neighborhood Hits	163	Target Neighborhood Hits	114	Shared Neighborhood Hits	96
SwissProt Accessions	P55055, Q12970	Gene names	NR1H2, LXRB, NER, UNR
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Nuclear receptor NER).

PXR_MOUSE
NC score	0.845950 (rank : 67)	θ value	1.16975e-15 (rank : 72)
Query Neighborhood Hits	163	Target Neighborhood Hits	107	Shared Neighborhood Hits	96
SwissProt Accessions	O54915	Gene names	Nr1i2, Pxr
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor).

TR2_MOUSE
NC score	0.845241 (rank : 68)	θ value	1.80466e-16 (rank : 62)
Query Neighborhood Hits	163	Target Neighborhood Hits	100	Shared Neighborhood Hits	96
SwissProt Accessions	Q505F1, P97763, Q3UIJ7, Q4U1Z4, Q60927, Q62152, Q8VIJ3	Gene names	Nr2c1, Tr2, Tr2-11
Domain Architecture	No domain graphic available
Description	Orphan nuclear receptor TR2 (Testicular receptor 2) (mTR2).

VDR_MOUSE
NC score	0.843201 (rank : 69)	θ value	1.09485e-13 (rank : 84)
Query Neighborhood Hits	163	Target Neighborhood Hits	103	Shared Neighborhood Hits	95
SwissProt Accessions	P48281	Gene names	Vdr, Nr1i1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

NR1D1_HUMAN
NC score	0.842440 (rank : 70)	θ value	6.00763e-12 (rank : 88)
Query Neighborhood Hits	163	Target Neighborhood Hits	140	Shared Neighborhood Hits	96
SwissProt Accessions	P20393, Q15304	Gene names	NR1D1, EAR1, HREV, THRAL
Domain Architecture
Description	Orphan nuclear receptor NR1D1 (V-erbA-related protein EAR-1) (Rev- erbA-alpha).

RORB_MOUSE
NC score	0.842115 (rank : 71)	θ value	1.80466e-16 (rank : 61)
Query Neighborhood Hits	163	Target Neighborhood Hits	99	Shared Neighborhood Hits	94
SwissProt Accessions	Q8R1B8	Gene names	Rorb, Nr1f2
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

RORB_HUMAN
NC score	0.841881 (rank : 72)	θ value	1.80466e-16 (rank : 60)
Query Neighborhood Hits	163	Target Neighborhood Hits	99	Shared Neighborhood Hits	94
SwissProt Accessions	Q92753, Q8WX73	Gene names	RORB, NR1F2, RZRB
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

TR4_HUMAN
NC score	0.841737 (rank : 73)	θ value	1.99529e-15 (rank : 73)
Query Neighborhood Hits	163	Target Neighborhood Hits	117	Shared Neighborhood Hits	96
SwissProt Accessions	P49116, P55092	Gene names	NR2C2, TAK1, TR4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

RORA_HUMAN
NC score	0.841708 (rank : 74)	θ value	2.35696e-16 (rank : 63)
Query Neighborhood Hits	163	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P35398, P35397, P35399, P45445, Q96H83	Gene names	RORA, NR1F1, RZRA
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

VDR_HUMAN
NC score	0.841544 (rank : 75)	θ value	1.09485e-13 (rank : 83)
Query Neighborhood Hits	163	Target Neighborhood Hits	112	Shared Neighborhood Hits	95
SwissProt Accessions	P11473	Gene names	VDR, NR1I1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

TR4_MOUSE
NC score	0.841504 (rank : 76)	θ value	2.60593e-15 (rank : 74)
Query Neighborhood Hits	163	Target Neighborhood Hits	115	Shared Neighborhood Hits	96
SwissProt Accessions	P49117, P55093	Gene names	Nr2c2, Mtr2r1, Tak1, Tr4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

RORG_MOUSE
NC score	0.840383 (rank : 77)	θ value	4.44505e-15 (rank : 77)
Query Neighborhood Hits	163	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	P51450, Q61027, Q91YT5, Q9QXD9, Q9R177	Gene names	Rorc, Nr1f3, Rorg, Thor
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma) (Thymus orphan receptor) (TOR).

RORA_MOUSE
NC score	0.840181 (rank : 78)	θ value	2.35696e-16 (rank : 64)
Query Neighborhood Hits	163	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P51448, P70283, P97741, P97773, Q923G1	Gene names	Rora, Nr1f1, Rzra
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

THA_HUMAN
NC score	0.840014 (rank : 79)	θ value	6.85773e-16 (rank : 68)
Query Neighborhood Hits	163	Target Neighborhood Hits	113	Shared Neighborhood Hits	96
SwissProt Accessions	P10827, P21205, Q8N6A1, Q96H73	Gene names	THRA, ERBA1, NR1A1, THRA1
Domain Architecture
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1) (EAR-7) (EAR7).

THA_MOUSE
NC score	0.839781 (rank : 80)	θ value	5.25075e-16 (rank : 67)
Query Neighborhood Hits	163	Target Neighborhood Hits	113	Shared Neighborhood Hits	96
SwissProt Accessions	P63058, P10685, P15827, P16416, P37241, Q63107, Q63195, Q63196, Q99146	Gene names	Thra, C-erba-alpha, Nr1a1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1).

PXR_HUMAN
NC score	0.839419 (rank : 81)	θ value	4.44505e-15 (rank : 76)
Query Neighborhood Hits	163	Target Neighborhood Hits	107	Shared Neighborhood Hits	96
SwissProt Accessions	O75469, Q96AC7, Q9UJ22, Q9UJ23, Q9UJ24, Q9UJ25, Q9UJ26, Q9UJ27	Gene names	NR1I2, PXR
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor) (Orphan nuclear receptor PAR1) (Steroid and xenobiotic receptor) (SXR).

RORG_HUMAN
NC score	0.835503 (rank : 82)	θ value	5.8054e-15 (rank : 78)
Query Neighborhood Hits	163	Target Neighborhood Hits	119	Shared Neighborhood Hits	96
SwissProt Accessions	P51449, Q8N5V7, Q8NCY8	Gene names	RORC, NR1F3, RORG, RZRG
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma).

NR1D2_HUMAN
NC score	0.833577 (rank : 83)	θ value	1.33837e-11 (rank : 89)
Query Neighborhood Hits	163	Target Neighborhood Hits	115	Shared Neighborhood Hits	94
SwissProt Accessions	Q14995, O00402, Q86XD4	Gene names	NR1D2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (EAR-1R) (Orphan nuclear hormone receptor BD73).

NR1D2_MOUSE
NC score	0.831294 (rank : 84)	θ value	1.33837e-11 (rank : 90)
Query Neighborhood Hits	163	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	Q60674, Q60646	Gene names	Nr1d2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (Orphan nuclear receptor RVR).

THB2_HUMAN
NC score	0.830999 (rank : 85)	θ value	9.90251e-15 (rank : 79)
Query Neighborhood Hits	163	Target Neighborhood Hits	104	Shared Neighborhood Hits	96
SwissProt Accessions	P37243	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor beta-2.

THB2_MOUSE
NC score	0.828190 (rank : 86)	θ value	5.43371e-13 (rank : 86)
Query Neighborhood Hits	163	Target Neighborhood Hits	106	Shared Neighborhood Hits	96
SwissProt Accessions	P37244	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-2.

THB1_HUMAN
NC score	0.827931 (rank : 87)	θ value	7.09661e-13 (rank : 87)
Query Neighborhood Hits	163	Target Neighborhood Hits	106	Shared Neighborhood Hits	96
SwissProt Accessions	P10828, Q13986	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture
Description	Thyroid hormone receptor beta-1.

THB1_MOUSE
NC score	0.827724 (rank : 88)	θ value	5.43371e-13 (rank : 85)
Query Neighborhood Hits	163	Target Neighborhood Hits	105	Shared Neighborhood Hits	96
SwissProt Accessions	P37242	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-1.

PPARA_HUMAN
NC score	0.825954 (rank : 89)	θ value	3.89403e-11 (rank : 92)
Query Neighborhood Hits	163	Target Neighborhood Hits	100	Shared Neighborhood Hits	94
SwissProt Accessions	Q07869, Q16241, Q92486, Q92689, Q9Y3N1	Gene names	PPARA, NR1C1, PPAR
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

PPARG_HUMAN
NC score	0.825790 (rank : 90)	θ value	4.91457e-14 (rank : 81)
Query Neighborhood Hits	163	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37231, O00684, O00710, O14515, Q15178, Q15179, Q15180, Q15832, Q86U60, Q96J12	Gene names	PPARG, NR1C3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

PPARA_MOUSE
NC score	0.825211 (rank : 91)	θ value	2.98157e-11 (rank : 91)
Query Neighborhood Hits	163	Target Neighborhood Hits	99	Shared Neighborhood Hits	95
SwissProt Accessions	P23204	Gene names	Ppara, Nr1c1, Ppar
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

PPARG_MOUSE
NC score	0.824731 (rank : 92)	θ value	4.91457e-14 (rank : 82)
Query Neighborhood Hits	163	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37238	Gene names	Pparg, Nr1c3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

PPARD_HUMAN
NC score	0.820020 (rank : 93)	θ value	3.89403e-11 (rank : 93)
Query Neighborhood Hits	163	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q03181, Q7Z5K0, Q9BUD4	Gene names	PPARD, NR1C2, PPARB
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1) (NUCI).

PPARD_MOUSE
NC score	0.816935 (rank : 94)	θ value	5.08577e-11 (rank : 94)
Query Neighborhood Hits	163	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	P35396, P37239	Gene names	Ppard, Nr1c2, Pparb
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1).

SHP_HUMAN
NC score	0.410300 (rank : 95)	θ value	2.36792 (rank : 124)
Query Neighborhood Hits	163	Target Neighborhood Hits	57	Shared Neighborhood Hits	54
SwissProt Accessions	Q15466, Q5QP36	Gene names	NR0B2, SHP
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

SHP_MOUSE
NC score	0.406346 (rank : 96)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	163	Target Neighborhood Hits	53	Shared Neighborhood Hits	51
SwissProt Accessions	Q62227, Q53Z53	Gene names	Nr0b2, Shp
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

DAX1_MOUSE
NC score	0.399195 (rank : 97)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	163	Target Neighborhood Hits	70	Shared Neighborhood Hits	58
SwissProt Accessions	Q61066, O09068, O09147	Gene names	Nr0b1, Ahch, Dax1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1).

DAX1_HUMAN
NC score	0.380036 (rank : 98)	θ value	2.36792 (rank : 121)
Query Neighborhood Hits	163	Target Neighborhood Hits	65	Shared Neighborhood Hits	57
SwissProt Accessions	P51843, Q96F69	Gene names	NR0B1, AHC, DAX1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1) (DSS-AHC critical region on the X chromosome protein 1).

NACAM_MOUSE
NC score	0.028188 (rank : 99)	θ value	0.163984 (rank : 100)
Query Neighborhood Hits	163	Target Neighborhood Hits	1866	Shared Neighborhood Hits	45
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

DOT1L_HUMAN
NC score	0.023662 (rank : 100)	θ value	0.813845 (rank : 109)
Query Neighborhood Hits	163	Target Neighborhood Hits	660	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

MAGE1_HUMAN
NC score	0.022787 (rank : 101)	θ value	0.00298849 (rank : 95)
Query Neighborhood Hits	163	Target Neighborhood Hits	1389	Shared Neighborhood Hits	43
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

NCOA6_MOUSE
NC score	0.021445 (rank : 102)	θ value	1.81305 (rank : 117)
Query Neighborhood Hits	163	Target Neighborhood Hits	1076	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

DAB1_MOUSE
NC score	0.020986 (rank : 103)	θ value	0.21417 (rank : 101)
Query Neighborhood Hits	163	Target Neighborhood Hits	145	Shared Neighborhood Hits	8
SwissProt Accessions	P97318, P97316, P97317	Gene names	Dab1
Domain Architecture
Description	Disabled homolog 1.

GA2L1_MOUSE
NC score	0.020715 (rank : 104)	θ value	0.0961366 (rank : 98)
Query Neighborhood Hits	163	Target Neighborhood Hits	114	Shared Neighborhood Hits	8
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

OGFR_HUMAN
NC score	0.020021 (rank : 105)	θ value	0.0563607 (rank : 97)
Query Neighborhood Hits	163	Target Neighborhood Hits	1582	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

NCOA6_HUMAN
NC score	0.018418 (rank : 106)	θ value	4.03905 (rank : 133)
Query Neighborhood Hits	163	Target Neighborhood Hits	1202	Shared Neighborhood Hits	39
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

DNM3A_HUMAN
NC score	0.017967 (rank : 107)	θ value	0.21417 (rank : 102)
Query Neighborhood Hits	163	Target Neighborhood Hits	104	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y6K1, Q8WXU9	Gene names	DNMT3A
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA).

BRCA1_MOUSE
NC score	0.017176 (rank : 108)	θ value	0.0330416 (rank : 96)
Query Neighborhood Hits	163	Target Neighborhood Hits	436	Shared Neighborhood Hits	6
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

DAB1_HUMAN
NC score	0.016322 (rank : 109)	θ value	3.0926 (rank : 125)
Query Neighborhood Hits	163	Target Neighborhood Hits	219	Shared Neighborhood Hits	13
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

HNF1A_HUMAN
NC score	0.016039 (rank : 110)	θ value	1.06291 (rank : 112)
Query Neighborhood Hits	163	Target Neighborhood Hits	193	Shared Neighborhood Hits	11
SwissProt Accessions	P20823, Q99861	Gene names	TCF1, HNF1A
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1) (Transcription factor 1) (TCF-1).

SDC3_HUMAN
NC score	0.014011 (rank : 111)	θ value	4.03905 (rank : 135)
Query Neighborhood Hits	163	Target Neighborhood Hits	103	Shared Neighborhood Hits	8
SwissProt Accessions	O75056, Q5T1Z6, Q5T1Z7, Q96CT3, Q96PR8	Gene names	SDC3, KIAA0468
Domain Architecture
Description	Syndecan-3 (SYND3).

JPH2_HUMAN
NC score	0.013614 (rank : 112)	θ value	0.0961366 (rank : 99)
Query Neighborhood Hits	163	Target Neighborhood Hits	639	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

ENAH_MOUSE
NC score	0.013384 (rank : 113)	θ value	0.62314 (rank : 107)
Query Neighborhood Hits	163	Target Neighborhood Hits	919	Shared Neighborhood Hits	22
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

HNF1A_MOUSE
NC score	0.013297 (rank : 114)	θ value	4.03905 (rank : 131)
Query Neighborhood Hits	163	Target Neighborhood Hits	212	Shared Neighborhood Hits	13
SwissProt Accessions	P22361	Gene names	Tcf1, Hnf-1, Hnf-1a, Hnf1a
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1).

FA13C_HUMAN
NC score	0.012952 (rank : 115)	θ value	0.813845 (rank : 110)
Query Neighborhood Hits	163	Target Neighborhood Hits	94	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

DNM3A_MOUSE
NC score	0.012591 (rank : 116)	θ value	4.03905 (rank : 130)
Query Neighborhood Hits	163	Target Neighborhood Hits	91	Shared Neighborhood Hits	4
SwissProt Accessions	O88508, Q3UH24, Q8CJ60, Q922J0, Q9CSE1	Gene names	Dnmt3a
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA).

BSN_MOUSE
NC score	0.012549 (rank : 117)	θ value	2.36792 (rank : 119)
Query Neighborhood Hits	163	Target Neighborhood Hits	2057	Shared Neighborhood Hits	45
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

MKL1_MOUSE
NC score	0.010720 (rank : 118)	θ value	4.03905 (rank : 132)
Query Neighborhood Hits	163	Target Neighborhood Hits	667	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

NEIL1_HUMAN
NC score	0.010581 (rank : 119)	θ value	3.0926 (rank : 128)
Query Neighborhood Hits	163	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q96FI4, Q6ZRA7, Q86XW7, Q9H6C3	Gene names	NEIL1
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 1 (EC 3.2.2.-) (EC 4.2.99.18) (Nei-like 1) (DNA glycosylase/AP lyase Neil1) (DNA-(apurinic or apyrimidinic site) lyase Neil1) (NEH1) (FPG1).

TISB_MOUSE
NC score	0.010303 (rank : 120)	θ value	4.03905 (rank : 138)
Query Neighborhood Hits	163	Target Neighborhood Hits	56	Shared Neighborhood Hits	6
SwissProt Accessions	P23950	Gene names	Zfp36l1, Brf1, Tis11b
Domain Architecture
Description	Butyrate response factor 1 (TIS11B protein).

TISB_HUMAN
NC score	0.010279 (rank : 121)	θ value	4.03905 (rank : 137)
Query Neighborhood Hits	163	Target Neighborhood Hits	56	Shared Neighborhood Hits	6
SwissProt Accessions	Q07352, Q13851	Gene names	ZFP36L1, BERG36, BRF1, ERF1, TIS11B
Domain Architecture
Description	Butyrate response factor 1 (TIS11B protein) (EGF-response factor 1) (ERF-1).

CLN5_HUMAN
NC score	0.009997 (rank : 122)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	163	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	O75503	Gene names	CLN5
Domain Architecture	No domain graphic available
Description	Ceroid-lipofuscinosis neuronal protein 5 (Protein CLN5).

PP2CG_HUMAN
NC score	0.009827 (rank : 123)	θ value	1.06291 (rank : 113)
Query Neighborhood Hits	163	Target Neighborhood Hits	140	Shared Neighborhood Hits	4
SwissProt Accessions	O15355	Gene names	PPM1G, PPM1C
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C).

SON_HUMAN
NC score	0.009255 (rank : 124)	θ value	3.0926 (rank : 129)
Query Neighborhood Hits	163	Target Neighborhood Hits	1568	Shared Neighborhood Hits	37
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

BAT3_MOUSE
NC score	0.009206 (rank : 125)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	163	Target Neighborhood Hits	518	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

K0056_HUMAN
NC score	0.009164 (rank : 126)	θ value	5.27518 (rank : 142)
Query Neighborhood Hits	163	Target Neighborhood Hits	107	Shared Neighborhood Hits	4
SwissProt Accessions	P42695	Gene names	KIAA0056
Domain Architecture	No domain graphic available
Description	Protein KIAA0056.

GNAS1_HUMAN
NC score	0.009143 (rank : 127)	θ value	0.21417 (rank : 103)
Query Neighborhood Hits	163	Target Neighborhood Hits	278	Shared Neighborhood Hits	16
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

RTN1_HUMAN
NC score	0.009003 (rank : 128)	θ value	2.36792 (rank : 123)
Query Neighborhood Hits	163	Target Neighborhood Hits	173	Shared Neighborhood Hits	9
SwissProt Accessions	Q16799, Q16800, Q16801	Gene names	RTN1, NSP
Domain Architecture
Description	Reticulon-1 (Neuroendocrine-specific protein).

CMTA2_MOUSE
NC score	0.008928 (rank : 129)	θ value	2.36792 (rank : 120)
Query Neighborhood Hits	163	Target Neighborhood Hits	216	Shared Neighborhood Hits	10
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

TULP4_HUMAN
NC score	0.008795 (rank : 130)	θ value	1.81305 (rank : 118)
Query Neighborhood Hits	163	Target Neighborhood Hits	426	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

GNAS1_MOUSE
NC score	0.008401 (rank : 131)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	163	Target Neighborhood Hits	651	Shared Neighborhood Hits	20
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

K1949_MOUSE
NC score	0.008127 (rank : 132)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	163	Target Neighborhood Hits	134	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BQ30, Q3UDS6, Q8CEY9, Q8R3D8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1949 homolog.

CI040_MOUSE
NC score	0.008037 (rank : 133)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	163	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VCE4, Q8BJJ5	Gene names
Domain Architecture	No domain graphic available
Description	Protein C9orf40 homolog.

SUSD4_MOUSE
NC score	0.007987 (rank : 134)	θ value	5.27518 (rank : 144)
Query Neighborhood Hits	163	Target Neighborhood Hits	122	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

JIP2_HUMAN
NC score	0.006962 (rank : 135)	θ value	5.27518 (rank : 141)
Query Neighborhood Hits	163	Target Neighborhood Hits	288	Shared Neighborhood Hits	11
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

F100B_HUMAN
NC score	0.006480 (rank : 136)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	163	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IYN6	Gene names	FAM100B
Domain Architecture	No domain graphic available
Description	Protein FAM100B.

PAPOG_MOUSE
NC score	0.006296 (rank : 137)	θ value	2.36792 (rank : 122)
Query Neighborhood Hits	163	Target Neighborhood Hits	103	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PCL9, Q8BZC9	Gene names	Papolg
Domain Architecture	No domain graphic available
Description	Poly(A) polymerase gamma (EC 2.7.7.19) (PAP gamma) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3' adenylating enzyme).

NBR1_HUMAN
NC score	0.006231 (rank : 138)	θ value	5.27518 (rank : 143)
Query Neighborhood Hits	163	Target Neighborhood Hits	105	Shared Neighborhood Hits	2
SwissProt Accessions	Q14596, Q13173, Q15026, Q96GB6, Q9NRF7	Gene names	NBR1, 1A13B, KIAA0049, M17S2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2) (1A1-3B).

TRIP6_HUMAN
NC score	0.006210 (rank : 139)	θ value	0.47712 (rank : 105)
Query Neighborhood Hits	163	Target Neighborhood Hits	228	Shared Neighborhood Hits	4
SwissProt Accessions	Q15654, O15170, O15275, Q9BTB2, Q9UNT4	Gene names	TRIP6, OIP1
Domain Architecture
Description	Thyroid receptor-interacting protein 6 (TRIP6) (OPA-interacting protein 1) (Zyxin-related protein 1) (ZRP-1).

DMRTD_MOUSE
NC score	0.005963 (rank : 140)	θ value	5.27518 (rank : 140)
Query Neighborhood Hits	163	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CGW9	Gene names	Dmrtc2, Dmrt7
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2 (Doublesex- and mab-3-related transcription factor 7).

HAX1_MOUSE
NC score	0.005922 (rank : 141)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	163	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	O35387	Gene names	Hax1, Hs1bp1
Domain Architecture	No domain graphic available
Description	HS1-associating protein X-1 (HAX-1) (HS1-binding protein).

IP3KB_HUMAN
NC score	0.005846 (rank : 142)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	163	Target Neighborhood Hits	124	Shared Neighborhood Hits	7
SwissProt Accessions	P27987, Q5VWL9, Q5VWM0, Q96BZ2, Q96JS1, Q9UH47	Gene names	ITPKB
Domain Architecture
Description	Inositol-trisphosphate 3-kinase B (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase B) (IP3K B) (IP3 3-kinase B) (IP3K-B).

BTBDC_HUMAN
NC score	0.005313 (rank : 143)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	163	Target Neighborhood Hits	248	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

CENG1_HUMAN
NC score	0.005180 (rank : 144)	θ value	0.47712 (rank : 104)
Query Neighborhood Hits	163	Target Neighborhood Hits	544	Shared Neighborhood Hits	13
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

RUNX1_HUMAN
NC score	0.004961 (rank : 145)	θ value	4.03905 (rank : 134)
Query Neighborhood Hits	163	Target Neighborhood Hits	94	Shared Neighborhood Hits	3
SwissProt Accessions	Q01196, O60472, O60473, O76047, O76089, Q13081, Q13755, Q13756, Q13757, Q13758, Q13759, Q15341, Q15343, Q16122, Q16284, Q16285, Q16286, Q16346, Q16347, Q92479	Gene names	RUNX1, AML1, CBFA2
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

KCNH2_MOUSE
NC score	0.003471 (rank : 146)	θ value	3.0926 (rank : 126)
Query Neighborhood Hits	163	Target Neighborhood Hits	165	Shared Neighborhood Hits	11
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

XKR6_HUMAN
NC score	0.003212 (rank : 147)	θ value	6.88961 (rank : 151)
Query Neighborhood Hits	163	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q5GH73, Q8TBA0	Gene names	XKR6, C8orf21, C8orf7, XRG6
Domain Architecture	No domain graphic available
Description	XK-related protein 6.

FGD3_HUMAN
NC score	0.002667 (rank : 148)	θ value	1.38821 (rank : 114)
Query Neighborhood Hits	163	Target Neighborhood Hits	249	Shared Neighborhood Hits	4
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

SHAN1_HUMAN
NC score	0.002640 (rank : 149)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	163	Target Neighborhood Hits	1041	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

DREB_MOUSE
NC score	0.001962 (rank : 150)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	163	Target Neighborhood Hits	446	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

TBCD4_MOUSE
NC score	0.001365 (rank : 151)	θ value	6.88961 (rank : 150)
Query Neighborhood Hits	163	Target Neighborhood Hits	276	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BYJ6, Q5DU23, Q66JU2, Q6P2M2, Q8BMH6, Q8BXM2	Gene names	Tbc1d4, Kiaa0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

KIF22_HUMAN
NC score	0.001114 (rank : 152)	θ value	3.0926 (rank : 127)
Query Neighborhood Hits	163	Target Neighborhood Hits	110	Shared Neighborhood Hits	2
SwissProt Accessions	Q14807, O94814, Q9BT46	Gene names	KIF22, KID, KNSL4
Domain Architecture
Description	Kinesin-like protein KIF22 (Kinesin-like DNA-binding protein) (Kinesin-like protein 4).

RFIP4_HUMAN
NC score	0.000814 (rank : 153)	θ value	0.813845 (rank : 111)
Query Neighborhood Hits	163	Target Neighborhood Hits	785	Shared Neighborhood Hits	6
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

C1QR1_HUMAN
NC score	0.000698 (rank : 154)	θ value	0.813845 (rank : 108)
Query Neighborhood Hits	163	Target Neighborhood Hits	493	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

CILP2_HUMAN
NC score	0.000409 (rank : 155)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	163	Target Neighborhood Hits	307	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

RIMB1_HUMAN
NC score	-0.001033 (rank : 156)	θ value	8.99809 (rank : 162)
Query Neighborhood Hits	163	Target Neighborhood Hits	1479	Shared Neighborhood Hits	21
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

WDR33_HUMAN
NC score	-0.002053 (rank : 157)	θ value	8.99809 (rank : 163)
Query Neighborhood Hits	163	Target Neighborhood Hits	638	Shared Neighborhood Hits	14
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

ZN516_HUMAN
NC score	-0.002523 (rank : 158)	θ value	0.47712 (rank : 106)
Query Neighborhood Hits	163	Target Neighborhood Hits	854	Shared Neighborhood Hits	11
SwissProt Accessions	Q92618	Gene names	ZNF516, KIAA0222
Domain Architecture	No domain graphic available
Description	Zinc finger protein 516.

SSPO_MOUSE
NC score	-0.002549 (rank : 159)	θ value	4.03905 (rank : 136)
Query Neighborhood Hits	163	Target Neighborhood Hits	800	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

ZN516_MOUSE
NC score	-0.002784 (rank : 160)	θ value	4.03905 (rank : 139)
Query Neighborhood Hits	163	Target Neighborhood Hits	1197	Shared Neighborhood Hits	25
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

FOG1_MOUSE
NC score	-0.004972 (rank : 161)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	163	Target Neighborhood Hits	1237	Shared Neighborhood Hits	22
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

POGZ_HUMAN
NC score	-0.005528 (rank : 162)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	163	Target Neighborhood Hits	745	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z3K3, O75049, Q8TDZ7, Q9Y4X7	Gene names	POGZ, KIAA0461
Domain Architecture
Description	Pogo transposable element with ZNF domain.

CDC2_MOUSE
NC score	-0.006179 (rank : 163)	θ value	1.81305 (rank : 116)
Query Neighborhood Hits	163	Target Neighborhood Hits	838	Shared Neighborhood Hits	5
SwissProt Accessions	P11440, P70337, Q3TI12	Gene names	Cdc2, Cdc2a
Domain Architecture
Description	Cell division control protein 2 homolog (EC 2.7.11.22) (EC 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1).

CDC2_HUMAN
NC score	-0.006216 (rank : 164)	θ value	1.81305 (rank : 115)
Query Neighborhood Hits	163	Target Neighborhood Hits	842	Shared Neighborhood Hits	5
SwissProt Accessions	P06493, O60764	Gene names	CDC2
Domain Architecture
Description	Cell division control protein 2 homolog (EC 2.7.11.22) (EC 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1).

MK07_MOUSE
NC score	-0.006742 (rank : 165)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	163	Target Neighborhood Hits	1054	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).