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Network neighborhood for query Sequence : BRCA1_MOUSE

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BRCA1_MOUSE
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

BRCA1_HUMAN
θ value	0 (rank : 1)	NC score	0.931605 (rank : 2)
Query Neighborhood Hits	436	Target Neighborhood Hits	381	Shared Neighborhood Hits	229
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

BRCA1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	436	Target Neighborhood Hits	436	Shared Neighborhood Hits	436
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

BARD1_HUMAN
θ value	3.89403e-11 (rank : 3)	NC score	0.212134 (rank : 198)
Query Neighborhood Hits	436	Target Neighborhood Hits	427	Shared Neighborhood Hits	109
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

MCPH1_MOUSE
θ value	3.29651e-10 (rank : 4)	NC score	0.254805 (rank : 175)
Query Neighborhood Hits	436	Target Neighborhood Hits	116	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

BARD1_MOUSE
θ value	7.34386e-10 (rank : 5)	NC score	0.209665 (rank : 199)
Query Neighborhood Hits	436	Target Neighborhood Hits	411	Shared Neighborhood Hits	102
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

MCPH1_HUMAN
θ value	1.80886e-08 (rank : 6)	NC score	0.243378 (rank : 182)
Query Neighborhood Hits	436	Target Neighborhood Hits	85	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NEM0, Q66GU1, Q9H9C7	Gene names	MCPH1
Domain Architecture
Description	Microcephalin.

TRI31_HUMAN
θ value	1.80886e-08 (rank : 7)	NC score	0.604627 (rank : 3)
Query Neighborhood Hits	436	Target Neighborhood Hits	299	Shared Neighborhood Hits	194
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

RO52_MOUSE
θ value	2.36244e-08 (rank : 8)	NC score	0.518967 (rank : 32)
Query Neighborhood Hits	436	Target Neighborhood Hits	360	Shared Neighborhood Hits	194
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

SMRA3_MOUSE
θ value	4.0297e-08 (rank : 9)	NC score	0.355417 (rank : 119)
Query Neighborhood Hits	436	Target Neighborhood Hits	267	Shared Neighborhood Hits	179
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

TRI11_MOUSE
θ value	6.87365e-08 (rank : 10)	NC score	0.519904 (rank : 29)
Query Neighborhood Hits	436	Target Neighborhood Hits	329	Shared Neighborhood Hits	191
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI30_MOUSE
θ value	6.87365e-08 (rank : 11)	NC score	0.561019 (rank : 8)
Query Neighborhood Hits	436	Target Neighborhood Hits	434	Shared Neighborhood Hits	205
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

SMRA3_HUMAN
θ value	8.97725e-08 (rank : 12)	NC score	0.364173 (rank : 113)
Query Neighborhood Hits	436	Target Neighborhood Hits	265	Shared Neighborhood Hits	181
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

TRI11_HUMAN
θ value	8.97725e-08 (rank : 13)	NC score	0.518656 (rank : 33)
Query Neighborhood Hits	436	Target Neighborhood Hits	316	Shared Neighborhood Hits	189
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI22_HUMAN
θ value	8.97725e-08 (rank : 14)	NC score	0.545684 (rank : 12)
Query Neighborhood Hits	436	Target Neighborhood Hits	396	Shared Neighborhood Hits	196
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI26_MOUSE
θ value	1.99992e-07 (rank : 15)	NC score	0.567681 (rank : 5)
Query Neighborhood Hits	436	Target Neighborhood Hits	339	Shared Neighborhood Hits	200
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI26_HUMAN
θ value	2.61198e-07 (rank : 16)	NC score	0.567473 (rank : 6)
Query Neighborhood Hits	436	Target Neighborhood Hits	335	Shared Neighborhood Hits	200
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI50_HUMAN
θ value	2.61198e-07 (rank : 17)	NC score	0.533434 (rank : 21)
Query Neighborhood Hits	436	Target Neighborhood Hits	294	Shared Neighborhood Hits	194
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRIM4_HUMAN
θ value	2.61198e-07 (rank : 18)	NC score	0.544475 (rank : 13)
Query Neighborhood Hits	436	Target Neighborhood Hits	321	Shared Neighborhood Hits	194
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

RING2_HUMAN
θ value	4.45536e-07 (rank : 19)	NC score	0.485523 (rank : 67)
Query Neighborhood Hits	436	Target Neighborhood Hits	201	Shared Neighborhood Hits	154
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	4.45536e-07 (rank : 20)	NC score	0.485454 (rank : 68)
Query Neighborhood Hits	436	Target Neighborhood Hits	199	Shared Neighborhood Hits	153
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RO52_HUMAN
θ value	4.45536e-07 (rank : 21)	NC score	0.519420 (rank : 31)
Query Neighborhood Hits	436	Target Neighborhood Hits	419	Shared Neighborhood Hits	206
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRIM5_HUMAN
θ value	4.45536e-07 (rank : 22)	NC score	0.538087 (rank : 17)
Query Neighborhood Hits	436	Target Neighborhood Hits	424	Shared Neighborhood Hits	197
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRI25_MOUSE
θ value	5.81887e-07 (rank : 23)	NC score	0.517190 (rank : 34)
Query Neighborhood Hits	436	Target Neighborhood Hits	446	Shared Neighborhood Hits	193
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI34_HUMAN
θ value	5.81887e-07 (rank : 24)	NC score	0.519648 (rank : 30)
Query Neighborhood Hits	436	Target Neighborhood Hits	416	Shared Neighborhood Hits	173
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI39_HUMAN
θ value	7.59969e-07 (rank : 25)	NC score	0.511842 (rank : 40)
Query Neighborhood Hits	436	Target Neighborhood Hits	693	Shared Neighborhood Hits	211
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI39_MOUSE
θ value	7.59969e-07 (rank : 26)	NC score	0.512298 (rank : 38)
Query Neighborhood Hits	436	Target Neighborhood Hits	691	Shared Neighborhood Hits	213
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRIM6_MOUSE
θ value	7.59969e-07 (rank : 27)	NC score	0.527751 (rank : 25)
Query Neighborhood Hits	436	Target Neighborhood Hits	451	Shared Neighborhood Hits	199
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRI50_MOUSE
θ value	9.92553e-07 (rank : 28)	NC score	0.532040 (rank : 23)
Query Neighborhood Hits	436	Target Neighborhood Hits	326	Shared Neighborhood Hits	203
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

RING1_MOUSE
θ value	1.29631e-06 (rank : 29)	NC score	0.495671 (rank : 56)
Query Neighborhood Hits	436	Target Neighborhood Hits	220	Shared Neighborhood Hits	157
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RING1_HUMAN
θ value	1.69304e-06 (rank : 30)	NC score	0.501201 (rank : 51)
Query Neighborhood Hits	436	Target Neighborhood Hits	219	Shared Neighborhood Hits	157
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

TRI43_HUMAN
θ value	1.69304e-06 (rank : 31)	NC score	0.536159 (rank : 18)
Query Neighborhood Hits	436	Target Neighborhood Hits	341	Shared Neighborhood Hits	186
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI60_HUMAN
θ value	2.21117e-06 (rank : 32)	NC score	0.525619 (rank : 26)
Query Neighborhood Hits	436	Target Neighborhood Hits	357	Shared Neighborhood Hits	204
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRI68_MOUSE
θ value	2.88788e-06 (rank : 33)	NC score	0.514457 (rank : 36)
Query Neighborhood Hits	436	Target Neighborhood Hits	356	Shared Neighborhood Hits	194
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRI27_HUMAN
θ value	3.77169e-06 (rank : 34)	NC score	0.488744 (rank : 62)
Query Neighborhood Hits	436	Target Neighborhood Hits	273	Shared Neighborhood Hits	181
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRIM6_HUMAN
θ value	3.77169e-06 (rank : 35)	NC score	0.521486 (rank : 28)
Query Neighborhood Hits	436	Target Neighborhood Hits	412	Shared Neighborhood Hits	192
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRI68_HUMAN
θ value	4.92598e-06 (rank : 36)	NC score	0.512164 (rank : 39)
Query Neighborhood Hits	436	Target Neighborhood Hits	267	Shared Neighborhood Hits	180
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TRI62_MOUSE
θ value	8.40245e-06 (rank : 37)	NC score	0.501887 (rank : 50)
Query Neighborhood Hits	436	Target Neighborhood Hits	478	Shared Neighborhood Hits	189
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI27_MOUSE
θ value	1.09739e-05 (rank : 38)	NC score	0.482436 (rank : 69)
Query Neighborhood Hits	436	Target Neighborhood Hits	261	Shared Neighborhood Hits	177
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI25_HUMAN
θ value	1.43324e-05 (rank : 39)	NC score	0.493804 (rank : 57)
Query Neighborhood Hits	436	Target Neighborhood Hits	472	Shared Neighborhood Hits	196
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI62_HUMAN
θ value	1.87187e-05 (rank : 40)	NC score	0.492462 (rank : 58)
Query Neighborhood Hits	436	Target Neighborhood Hits	584	Shared Neighborhood Hits	193
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI73_HUMAN
θ value	1.87187e-05 (rank : 41)	NC score	0.560356 (rank : 9)
Query Neighborhood Hits	436	Target Neighborhood Hits	258	Shared Neighborhood Hits	184
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI74_HUMAN
θ value	1.87187e-05 (rank : 42)	NC score	0.556089 (rank : 10)
Query Neighborhood Hits	436	Target Neighborhood Hits	249	Shared Neighborhood Hits	178
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRI10_HUMAN
θ value	2.44474e-05 (rank : 43)	NC score	0.513850 (rank : 37)
Query Neighborhood Hits	436	Target Neighborhood Hits	315	Shared Neighborhood Hits	186
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI10_MOUSE
θ value	3.19293e-05 (rank : 44)	NC score	0.510002 (rank : 41)
Query Neighborhood Hits	436	Target Neighborhood Hits	285	Shared Neighborhood Hits	183
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI47_MOUSE
θ value	3.19293e-05 (rank : 45)	NC score	0.486556 (rank : 66)
Query Neighborhood Hits	436	Target Neighborhood Hits	295	Shared Neighborhood Hits	177
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

RAG1_HUMAN
θ value	4.1701e-05 (rank : 46)	NC score	0.451049 (rank : 81)
Query Neighborhood Hits	436	Target Neighborhood Hits	203	Shared Neighborhood Hits	150
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RAG1_MOUSE
θ value	4.1701e-05 (rank : 47)	NC score	0.444015 (rank : 84)
Query Neighborhood Hits	436	Target Neighborhood Hits	189	Shared Neighborhood Hits	149
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

RN125_HUMAN
θ value	4.1701e-05 (rank : 48)	NC score	0.539619 (rank : 16)
Query Neighborhood Hits	436	Target Neighborhood Hits	230	Shared Neighborhood Hits	170
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

TRI12_MOUSE
θ value	4.1701e-05 (rank : 49)	NC score	0.566775 (rank : 7)
Query Neighborhood Hits	436	Target Neighborhood Hits	387	Shared Neighborhood Hits	191
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI32_HUMAN
θ value	4.1701e-05 (rank : 50)	NC score	0.473867 (rank : 72)
Query Neighborhood Hits	436	Target Neighborhood Hits	264	Shared Neighborhood Hits	154
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI32_MOUSE
θ value	4.1701e-05 (rank : 51)	NC score	0.473265 (rank : 73)
Query Neighborhood Hits	436	Target Neighborhood Hits	271	Shared Neighborhood Hits	155
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRI40_HUMAN
θ value	4.1701e-05 (rank : 52)	NC score	0.577524 (rank : 4)
Query Neighborhood Hits	436	Target Neighborhood Hits	279	Shared Neighborhood Hits	182
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI60_MOUSE
θ value	4.1701e-05 (rank : 53)	NC score	0.496911 (rank : 54)
Query Neighborhood Hits	436	Target Neighborhood Hits	240	Shared Neighborhood Hits	162
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

CM007_MOUSE
θ value	5.44631e-05 (rank : 54)	NC score	0.332237 (rank : 127)
Query Neighborhood Hits	436	Target Neighborhood Hits	416	Shared Neighborhood Hits	140
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

RNF8_MOUSE
θ value	5.44631e-05 (rank : 55)	NC score	0.454004 (rank : 78)
Query Neighborhood Hits	436	Target Neighborhood Hits	618	Shared Neighborhood Hits	214
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

TRI34_MOUSE
θ value	5.44631e-05 (rank : 56)	NC score	0.489309 (rank : 61)
Query Neighborhood Hits	436	Target Neighborhood Hits	332	Shared Neighborhood Hits	163
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI35_HUMAN
θ value	5.44631e-05 (rank : 57)	NC score	0.530287 (rank : 24)
Query Neighborhood Hits	436	Target Neighborhood Hits	382	Shared Neighborhood Hits	193
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

PZRN4_HUMAN
θ value	7.1131e-05 (rank : 58)	NC score	0.272698 (rank : 155)
Query Neighborhood Hits	436	Target Neighborhood Hits	438	Shared Neighborhood Hits	178
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

ZN313_MOUSE
θ value	7.1131e-05 (rank : 59)	NC score	0.543132 (rank : 14)
Query Neighborhood Hits	436	Target Neighborhood Hits	273	Shared Neighborhood Hits	192
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

CM007_HUMAN
θ value	9.29e-05 (rank : 60)	NC score	0.306312 (rank : 138)
Query Neighborhood Hits	436	Target Neighborhood Hits	422	Shared Neighborhood Hits	132
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

TRIM8_HUMAN
θ value	9.29e-05 (rank : 61)	NC score	0.505039 (rank : 45)
Query Neighborhood Hits	436	Target Neighborhood Hits	650	Shared Neighborhood Hits	194
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_MOUSE
θ value	9.29e-05 (rank : 62)	NC score	0.504534 (rank : 46)
Query Neighborhood Hits	436	Target Neighborhood Hits	674	Shared Neighborhood Hits	193
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

ZN313_HUMAN
θ value	9.29e-05 (rank : 63)	NC score	0.532137 (rank : 22)
Query Neighborhood Hits	436	Target Neighborhood Hits	264	Shared Neighborhood Hits	193
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

RNF5_MOUSE
θ value	0.000121331 (rank : 64)	NC score	0.449332 (rank : 82)
Query Neighborhood Hits	436	Target Neighborhood Hits	206	Shared Neighborhood Hits	150
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

TRI17_HUMAN
θ value	0.000121331 (rank : 65)	NC score	0.506649 (rank : 43)
Query Neighborhood Hits	436	Target Neighborhood Hits	318	Shared Neighborhood Hits	187
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

RN146_HUMAN
θ value	0.000158464 (rank : 66)	NC score	0.399011 (rank : 103)
Query Neighborhood Hits	436	Target Neighborhood Hits	162	Shared Neighborhood Hits	128
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RNF5_HUMAN
θ value	0.000158464 (rank : 67)	NC score	0.449051 (rank : 83)
Query Neighborhood Hits	436	Target Neighborhood Hits	206	Shared Neighborhood Hits	152
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

TRI17_MOUSE
θ value	0.000158464 (rank : 68)	NC score	0.488358 (rank : 63)
Query Neighborhood Hits	436	Target Neighborhood Hits	620	Shared Neighborhood Hits	196
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

RN146_MOUSE
θ value	0.00020696 (rank : 69)	NC score	0.395045 (rank : 108)
Query Neighborhood Hits	436	Target Neighborhood Hits	161	Shared Neighborhood Hits	127
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

RN168_MOUSE
θ value	0.00020696 (rank : 70)	NC score	0.472730 (rank : 74)
Query Neighborhood Hits	436	Target Neighborhood Hits	440	Shared Neighborhood Hits	193
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RNF39_HUMAN
θ value	0.00020696 (rank : 71)	NC score	0.458180 (rank : 76)
Query Neighborhood Hits	436	Target Neighborhood Hits	200	Shared Neighborhood Hits	150
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

TRAF6_HUMAN
θ value	0.00020696 (rank : 72)	NC score	0.405697 (rank : 98)
Query Neighborhood Hits	436	Target Neighborhood Hits	267	Shared Neighborhood Hits	167
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRI48_HUMAN
θ value	0.00020696 (rank : 73)	NC score	0.498299 (rank : 52)
Query Neighborhood Hits	436	Target Neighborhood Hits	192	Shared Neighborhood Hits	155
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

RN125_MOUSE
θ value	0.000270298 (rank : 74)	NC score	0.541729 (rank : 15)
Query Neighborhood Hits	436	Target Neighborhood Hits	220	Shared Neighborhood Hits	169
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

TRAF6_MOUSE
θ value	0.000270298 (rank : 75)	NC score	0.408839 (rank : 97)
Query Neighborhood Hits	436	Target Neighborhood Hits	255	Shared Neighborhood Hits	167
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

RN168_HUMAN
θ value	0.00035302 (rank : 76)	NC score	0.487374 (rank : 64)
Query Neighborhood Hits	436	Target Neighborhood Hits	370	Shared Neighborhood Hits	178
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN185_HUMAN
θ value	0.00035302 (rank : 77)	NC score	0.453256 (rank : 79)
Query Neighborhood Hits	436	Target Neighborhood Hits	213	Shared Neighborhood Hits	153
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
θ value	0.00035302 (rank : 78)	NC score	0.452347 (rank : 80)
Query Neighborhood Hits	436	Target Neighborhood Hits	211	Shared Neighborhood Hits	153
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

TRI13_MOUSE
θ value	0.00035302 (rank : 79)	NC score	0.533958 (rank : 19)
Query Neighborhood Hits	436	Target Neighborhood Hits	282	Shared Neighborhood Hits	182
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI35_MOUSE
θ value	0.00035302 (rank : 80)	NC score	0.524301 (rank : 27)
Query Neighborhood Hits	436	Target Neighborhood Hits	465	Shared Neighborhood Hits	196
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

RFC1_HUMAN
θ value	0.000461057 (rank : 81)	NC score	0.092756 (rank : 271)
Query Neighborhood Hits	436	Target Neighborhood Hits	352	Shared Neighborhood Hits	50
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

RNF8_HUMAN
θ value	0.000461057 (rank : 82)	NC score	0.425989 (rank : 92)
Query Neighborhood Hits	436	Target Neighborhood Hits	622	Shared Neighborhood Hits	211
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

TRI47_HUMAN
θ value	0.000461057 (rank : 83)	NC score	0.476119 (rank : 71)
Query Neighborhood Hits	436	Target Neighborhood Hits	286	Shared Neighborhood Hits	177
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRIM7_HUMAN
θ value	0.000461057 (rank : 84)	NC score	0.498288 (rank : 53)
Query Neighborhood Hits	436	Target Neighborhood Hits	336	Shared Neighborhood Hits	182
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRIM7_MOUSE
θ value	0.000461057 (rank : 85)	NC score	0.502518 (rank : 49)
Query Neighborhood Hits	436	Target Neighborhood Hits	358	Shared Neighborhood Hits	182
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRI13_HUMAN
θ value	0.000602161 (rank : 86)	NC score	0.533682 (rank : 20)
Query Neighborhood Hits	436	Target Neighborhood Hits	274	Shared Neighborhood Hits	182
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI18_HUMAN
θ value	0.000602161 (rank : 87)	NC score	0.402609 (rank : 102)
Query Neighborhood Hits	436	Target Neighborhood Hits	307	Shared Neighborhood Hits	168
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI18_MOUSE
θ value	0.000602161 (rank : 88)	NC score	0.402729 (rank : 101)
Query Neighborhood Hits	436	Target Neighborhood Hits	292	Shared Neighborhood Hits	168
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRI38_HUMAN
θ value	0.000786445 (rank : 89)	NC score	0.496093 (rank : 55)
Query Neighborhood Hits	436	Target Neighborhood Hits	373	Shared Neighborhood Hits	187
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

DMP1_MOUSE
θ value	0.00102713 (rank : 90)	NC score	0.118862 (rank : 238)
Query Neighborhood Hits	436	Target Neighborhood Hits	498	Shared Neighborhood Hits	70
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

ERCC5_MOUSE
θ value	0.00102713 (rank : 91)	NC score	0.076581 (rank : 296)
Query Neighborhood Hits	436	Target Neighborhood Hits	206	Shared Neighborhood Hits	29
SwissProt Accessions	P35689, Q61528, Q64248	Gene names	Ercc5, Ercc-5, Xpg
Domain Architecture
Description	DNA-repair protein complementing XP-G cells homolog (Xeroderma pigmentosum group G-complementing protein homolog) (DNA excision repair protein ERCC-5).

NPBL_MOUSE
θ value	0.00102713 (rank : 92)	NC score	0.108986 (rank : 246)
Query Neighborhood Hits	436	Target Neighborhood Hits	1041	Shared Neighborhood Hits	102
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PEX10_HUMAN
θ value	0.00134147 (rank : 93)	NC score	0.502683 (rank : 48)
Query Neighborhood Hits	436	Target Neighborhood Hits	255	Shared Neighborhood Hits	170
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

RAD18_HUMAN
θ value	0.00134147 (rank : 94)	NC score	0.357667 (rank : 116)
Query Neighborhood Hits	436	Target Neighborhood Hits	284	Shared Neighborhood Hits	149
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RAD18_MOUSE
θ value	0.00134147 (rank : 95)	NC score	0.371418 (rank : 111)
Query Neighborhood Hits	436	Target Neighborhood Hits	230	Shared Neighborhood Hits	141
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

UHRF2_HUMAN
θ value	0.00134147 (rank : 96)	NC score	0.334579 (rank : 123)
Query Neighborhood Hits	436	Target Neighborhood Hits	269	Shared Neighborhood Hits	161
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
θ value	0.00134147 (rank : 97)	NC score	0.330414 (rank : 129)
Query Neighborhood Hits	436	Target Neighborhood Hits	275	Shared Neighborhood Hits	160
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

DSPP_MOUSE
θ value	0.00175202 (rank : 98)	NC score	0.118780 (rank : 239)
Query Neighborhood Hits	436	Target Neighborhood Hits	491	Shared Neighborhood Hits	61
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

NIPBL_HUMAN
θ value	0.00228821 (rank : 99)	NC score	0.107857 (rank : 248)
Query Neighborhood Hits	436	Target Neighborhood Hits	1311	Shared Neighborhood Hits	119
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

RNF41_HUMAN
θ value	0.00228821 (rank : 100)	NC score	0.440062 (rank : 86)
Query Neighborhood Hits	436	Target Neighborhood Hits	226	Shared Neighborhood Hits	160
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	0.00228821 (rank : 101)	NC score	0.440191 (rank : 85)
Query Neighborhood Hits	436	Target Neighborhood Hits	224	Shared Neighborhood Hits	160
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

TRI59_HUMAN
θ value	0.00228821 (rank : 102)	NC score	0.503081 (rank : 47)
Query Neighborhood Hits	436	Target Neighborhood Hits	307	Shared Neighborhood Hits	175
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI59_MOUSE
θ value	0.00228821 (rank : 103)	NC score	0.505626 (rank : 44)
Query Neighborhood Hits	436	Target Neighborhood Hits	292	Shared Neighborhood Hits	175
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRIM1_HUMAN
θ value	0.00228821 (rank : 104)	NC score	0.398421 (rank : 105)
Query Neighborhood Hits	436	Target Neighborhood Hits	345	Shared Neighborhood Hits	177
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
θ value	0.00228821 (rank : 105)	NC score	0.395885 (rank : 107)
Query Neighborhood Hits	436	Target Neighborhood Hits	361	Shared Neighborhood Hits	180
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

UHRF1_MOUSE
θ value	0.00228821 (rank : 106)	NC score	0.286882 (rank : 148)
Query Neighborhood Hits	436	Target Neighborhood Hits	278	Shared Neighborhood Hits	158
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

RFWD2_HUMAN
θ value	0.00298849 (rank : 107)	NC score	0.300293 (rank : 142)
Query Neighborhood Hits	436	Target Neighborhood Hits	518	Shared Neighborhood Hits	189
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
θ value	0.00298849 (rank : 108)	NC score	0.302184 (rank : 140)
Query Neighborhood Hits	436	Target Neighborhood Hits	535	Shared Neighborhood Hits	193
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

PZRN3_HUMAN
θ value	0.00390308 (rank : 109)	NC score	0.270074 (rank : 159)
Query Neighborhood Hits	436	Target Neighborhood Hits	461	Shared Neighborhood Hits	181
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	0.00390308 (rank : 110)	NC score	0.270513 (rank : 157)
Query Neighborhood Hits	436	Target Neighborhood Hits	447	Shared Neighborhood Hits	180
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

TRAF2_HUMAN
θ value	0.00390308 (rank : 111)	NC score	0.242256 (rank : 183)
Query Neighborhood Hits	436	Target Neighborhood Hits	402	Shared Neighborhood Hits	124
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

TRI52_HUMAN
θ value	0.00390308 (rank : 112)	NC score	0.548448 (rank : 11)
Query Neighborhood Hits	436	Target Neighborhood Hits	213	Shared Neighborhood Hits	164
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

DSPP_HUMAN
θ value	0.00509761 (rank : 113)	NC score	0.120293 (rank : 237)
Query Neighborhood Hits	436	Target Neighborhood Hits	645	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

TRI46_HUMAN
θ value	0.00509761 (rank : 114)	NC score	0.357432 (rank : 118)
Query Neighborhood Hits	436	Target Neighborhood Hits	291	Shared Neighborhood Hits	151
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_MOUSE
θ value	0.00509761 (rank : 115)	NC score	0.358515 (rank : 115)
Query Neighborhood Hits	436	Target Neighborhood Hits	287	Shared Neighborhood Hits	152
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TCOF_MOUSE
θ value	0.00665767 (rank : 116)	NC score	0.069411 (rank : 317)
Query Neighborhood Hits	436	Target Neighborhood Hits	471	Shared Neighborhood Hits	30
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TRAF2_MOUSE
θ value	0.00665767 (rank : 117)	NC score	0.244610 (rank : 178)
Query Neighborhood Hits	436	Target Neighborhood Hits	394	Shared Neighborhood Hits	126
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

MIB1_HUMAN
θ value	0.00869519 (rank : 118)	NC score	0.103101 (rank : 256)
Query Neighborhood Hits	436	Target Neighborhood Hits	470	Shared Neighborhood Hits	105
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	0.00869519 (rank : 119)	NC score	0.103168 (rank : 255)
Query Neighborhood Hits	436	Target Neighborhood Hits	471	Shared Neighborhood Hits	105
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

TRI63_HUMAN
θ value	0.00869519 (rank : 120)	NC score	0.430114 (rank : 90)
Query Neighborhood Hits	436	Target Neighborhood Hits	298	Shared Neighborhood Hits	146
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

LNX1_HUMAN
θ value	0.0113563 (rank : 121)	NC score	0.268049 (rank : 162)
Query Neighborhood Hits	436	Target Neighborhood Hits	379	Shared Neighborhood Hits	169
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX1_MOUSE
θ value	0.0113563 (rank : 122)	NC score	0.261753 (rank : 167)
Query Neighborhood Hits	436	Target Neighborhood Hits	377	Shared Neighborhood Hits	161
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX2_MOUSE
θ value	0.0113563 (rank : 123)	NC score	0.261156 (rank : 170)
Query Neighborhood Hits	436	Target Neighborhood Hits	407	Shared Neighborhood Hits	173
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

NFH_HUMAN
θ value	0.0113563 (rank : 124)	NC score	0.033779 (rank : 413)
Query Neighborhood Hits	436	Target Neighborhood Hits	1242	Shared Neighborhood Hits	85
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RNF4_HUMAN
θ value	0.0113563 (rank : 125)	NC score	0.424374 (rank : 93)
Query Neighborhood Hits	436	Target Neighborhood Hits	212	Shared Neighborhood Hits	152
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
θ value	0.0113563 (rank : 126)	NC score	0.421245 (rank : 95)
Query Neighborhood Hits	436	Target Neighborhood Hits	212	Shared Neighborhood Hits	152
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

SRRM2_MOUSE
θ value	0.0113563 (rank : 127)	NC score	0.067660 (rank : 319)
Query Neighborhood Hits	436	Target Neighborhood Hits	1470	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TRI49_HUMAN
θ value	0.0113563 (rank : 128)	NC score	0.479176 (rank : 70)
Query Neighborhood Hits	436	Target Neighborhood Hits	199	Shared Neighborhood Hits	146
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

BRWD1_MOUSE
θ value	0.0148317 (rank : 129)	NC score	0.031947 (rank : 419)
Query Neighborhood Hits	436	Target Neighborhood Hits	478	Shared Neighborhood Hits	34
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

CHD1_MOUSE
θ value	0.0148317 (rank : 130)	NC score	0.046601 (rank : 378)
Query Neighborhood Hits	436	Target Neighborhood Hits	266	Shared Neighborhood Hits	23
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

KCNA4_HUMAN
θ value	0.0148317 (rank : 131)	NC score	0.022296 (rank : 453)
Query Neighborhood Hits	436	Target Neighborhood Hits	108	Shared Neighborhood Hits	5
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

LNX2_HUMAN
θ value	0.0148317 (rank : 132)	NC score	0.264936 (rank : 165)
Query Neighborhood Hits	436	Target Neighborhood Hits	389	Shared Neighborhood Hits	172
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

TRI41_HUMAN
θ value	0.0148317 (rank : 133)	NC score	0.467122 (rank : 75)
Query Neighborhood Hits	436	Target Neighborhood Hits	349	Shared Neighborhood Hits	168
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI56_HUMAN
θ value	0.0148317 (rank : 134)	NC score	0.389315 (rank : 109)
Query Neighborhood Hits	436	Target Neighborhood Hits	339	Shared Neighborhood Hits	167
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

MPP8_HUMAN
θ value	0.0193708 (rank : 135)	NC score	0.060951 (rank : 335)
Query Neighborhood Hits	436	Target Neighborhood Hits	948	Shared Neighborhood Hits	82
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

TRI63_MOUSE
θ value	0.0193708 (rank : 136)	NC score	0.438793 (rank : 87)
Query Neighborhood Hits	436	Target Neighborhood Hits	240	Shared Neighborhood Hits	143
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRIM2_HUMAN
θ value	0.0193708 (rank : 137)	NC score	0.404755 (rank : 99)
Query Neighborhood Hits	436	Target Neighborhood Hits	330	Shared Neighborhood Hits	187
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
θ value	0.0193708 (rank : 138)	NC score	0.403009 (rank : 100)
Query Neighborhood Hits	436	Target Neighborhood Hits	331	Shared Neighborhood Hits	186
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

CAC1H_MOUSE
θ value	0.0252991 (rank : 139)	NC score	0.025743 (rank : 436)
Query Neighborhood Hits	436	Target Neighborhood Hits	230	Shared Neighborhood Hits	16
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

JIP2_HUMAN
θ value	0.0252991 (rank : 140)	NC score	0.057656 (rank : 346)
Query Neighborhood Hits	436	Target Neighborhood Hits	288	Shared Neighborhood Hits	12
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

RN166_HUMAN
θ value	0.0252991 (rank : 141)	NC score	0.491282 (rank : 60)
Query Neighborhood Hits	436	Target Neighborhood Hits	240	Shared Neighborhood Hits	173
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
θ value	0.0252991 (rank : 142)	NC score	0.491369 (rank : 59)
Query Neighborhood Hits	436	Target Neighborhood Hits	248	Shared Neighborhood Hits	178
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

TRAF7_MOUSE
θ value	0.0252991 (rank : 143)	NC score	0.200325 (rank : 203)
Query Neighborhood Hits	436	Target Neighborhood Hits	470	Shared Neighborhood Hits	168
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

ZN179_HUMAN
θ value	0.0252991 (rank : 144)	NC score	0.486588 (rank : 65)
Query Neighborhood Hits	436	Target Neighborhood Hits	178	Shared Neighborhood Hits	146
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

BSN_MOUSE
θ value	0.0330416 (rank : 145)	NC score	0.059353 (rank : 338)
Query Neighborhood Hits	436	Target Neighborhood Hits	2057	Shared Neighborhood Hits	98
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

DTX3_HUMAN
θ value	0.0330416 (rank : 146)	NC score	0.317797 (rank : 134)
Query Neighborhood Hits	436	Target Neighborhood Hits	198	Shared Neighborhood Hits	141
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

DTX3_MOUSE
θ value	0.0330416 (rank : 147)	NC score	0.323743 (rank : 132)
Query Neighborhood Hits	436	Target Neighborhood Hits	202	Shared Neighborhood Hits	146
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

IWS1_HUMAN
θ value	0.0330416 (rank : 148)	NC score	0.103415 (rank : 253)
Query Neighborhood Hits	436	Target Neighborhood Hits	1241	Shared Neighborhood Hits	123
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PRGR_HUMAN
θ value	0.0330416 (rank : 149)	NC score	0.017176 (rank : 479)
Query Neighborhood Hits	436	Target Neighborhood Hits	163	Shared Neighborhood Hits	6
SwissProt Accessions	P06401, Q9UPF7	Gene names	PGR, NR3C3
Domain Architecture
Description	Progesterone receptor (PR).

SIAH2_HUMAN
θ value	0.0330416 (rank : 150)	NC score	0.153353 (rank : 227)
Query Neighborhood Hits	436	Target Neighborhood Hits	94	Shared Neighborhood Hits	60
SwissProt Accessions	O43255, O43270	Gene names	SIAH2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (hSiah2).

SIAH2_MOUSE
θ value	0.0330416 (rank : 151)	NC score	0.154008 (rank : 226)
Query Neighborhood Hits	436	Target Neighborhood Hits	101	Shared Neighborhood Hits	62
SwissProt Accessions	Q06986	Gene names	Siah2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (mSiah2).

TRAF7_HUMAN
θ value	0.0330416 (rank : 152)	NC score	0.199100 (rank : 204)
Query Neighborhood Hits	436	Target Neighborhood Hits	482	Shared Neighborhood Hits	175
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRI55_HUMAN
θ value	0.0330416 (rank : 153)	NC score	0.430343 (rank : 89)
Query Neighborhood Hits	436	Target Neighborhood Hits	292	Shared Neighborhood Hits	145
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

UHRF1_HUMAN
θ value	0.0431538 (rank : 154)	NC score	0.277631 (rank : 151)
Query Neighborhood Hits	436	Target Neighborhood Hits	272	Shared Neighborhood Hits	159
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

BSN_HUMAN
θ value	0.0563607 (rank : 155)	NC score	0.064933 (rank : 326)
Query Neighborhood Hits	436	Target Neighborhood Hits	1537	Shared Neighborhood Hits	92
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CP250_MOUSE
θ value	0.0563607 (rank : 156)	NC score	0.040498 (rank : 396)
Query Neighborhood Hits	436	Target Neighborhood Hits	1583	Shared Neighborhood Hits	109
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

DMP1_HUMAN
θ value	0.0563607 (rank : 157)	NC score	0.117392 (rank : 240)
Query Neighborhood Hits	436	Target Neighborhood Hits	491	Shared Neighborhood Hits	77
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

NHLC1_HUMAN
θ value	0.0563607 (rank : 158)	NC score	0.219401 (rank : 196)
Query Neighborhood Hits	436	Target Neighborhood Hits	91	Shared Neighborhood Hits	66
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

RC3H1_HUMAN
θ value	0.0563607 (rank : 159)	NC score	0.218458 (rank : 197)
Query Neighborhood Hits	436	Target Neighborhood Hits	433	Shared Neighborhood Hits	132
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RC3H1_MOUSE
θ value	0.0563607 (rank : 160)	NC score	0.227364 (rank : 193)
Query Neighborhood Hits	436	Target Neighborhood Hits	244	Shared Neighborhood Hits	127
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

TP53B_HUMAN
θ value	0.0563607 (rank : 161)	NC score	0.095781 (rank : 267)
Query Neighborhood Hits	436	Target Neighborhood Hits	413	Shared Neighborhood Hits	64
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TP53B_MOUSE
θ value	0.0563607 (rank : 162)	NC score	0.100136 (rank : 261)
Query Neighborhood Hits	436	Target Neighborhood Hits	644	Shared Neighborhood Hits	84
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TRI56_MOUSE
θ value	0.0563607 (rank : 163)	NC score	0.372115 (rank : 110)
Query Neighborhood Hits	436	Target Neighborhood Hits	255	Shared Neighborhood Hits	158
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

ACINU_HUMAN
θ value	0.0736092 (rank : 164)	NC score	0.073489 (rank : 304)
Query Neighborhood Hits	436	Target Neighborhood Hits	828	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

CAC1S_MOUSE
θ value	0.0736092 (rank : 165)	NC score	0.018439 (rank : 473)
Query Neighborhood Hits	436	Target Neighborhood Hits	98	Shared Neighborhood Hits	5
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CLSPN_HUMAN
θ value	0.0736092 (rank : 166)	NC score	0.055948 (rank : 353)
Query Neighborhood Hits	436	Target Neighborhood Hits	433	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

HUWE1_HUMAN
θ value	0.0736092 (rank : 167)	NC score	0.036611 (rank : 401)
Query Neighborhood Hits	436	Target Neighborhood Hits	443	Shared Neighborhood Hits	31
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HUWE1_MOUSE
θ value	0.0736092 (rank : 168)	NC score	0.034475 (rank : 410)
Query Neighborhood Hits	436	Target Neighborhood Hits	406	Shared Neighborhood Hits	27
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

IWS1_MOUSE
θ value	0.0736092 (rank : 169)	NC score	0.094340 (rank : 269)
Query Neighborhood Hits	436	Target Neighborhood Hits	1258	Shared Neighborhood Hits	116
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PRP4B_MOUSE
θ value	0.0736092 (rank : 170)	NC score	0.014075 (rank : 494)
Query Neighborhood Hits	436	Target Neighborhood Hits	1040	Shared Neighborhood Hits	49
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

TRI15_HUMAN
θ value	0.0736092 (rank : 171)	NC score	0.455583 (rank : 77)
Query Neighborhood Hits	436	Target Neighborhood Hits	395	Shared Neighborhood Hits	171
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRIM9_HUMAN
θ value	0.0736092 (rank : 172)	NC score	0.331032 (rank : 128)
Query Neighborhood Hits	436	Target Neighborhood Hits	294	Shared Neighborhood Hits	143
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRIM9_MOUSE
θ value	0.0736092 (rank : 173)	NC score	0.330101 (rank : 130)
Query Neighborhood Hits	436	Target Neighborhood Hits	274	Shared Neighborhood Hits	141
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

CBLC_MOUSE
θ value	0.0961366 (rank : 174)	NC score	0.181791 (rank : 213)
Query Neighborhood Hits	436	Target Neighborhood Hits	186	Shared Neighborhood Hits	118
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

JIP2_MOUSE
θ value	0.0961366 (rank : 175)	NC score	0.053979 (rank : 357)
Query Neighborhood Hits	436	Target Neighborhood Hits	144	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

SFRS4_MOUSE
θ value	0.0961366 (rank : 176)	NC score	0.044942 (rank : 382)
Query Neighborhood Hits	436	Target Neighborhood Hits	406	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

TMCC1_MOUSE
θ value	0.0961366 (rank : 177)	NC score	0.043442 (rank : 384)
Query Neighborhood Hits	436	Target Neighborhood Hits	315	Shared Neighborhood Hits	27
SwissProt Accessions	Q69ZZ6, Q8CEF4	Gene names	Tmcc1, Kiaa0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

TRI54_HUMAN
θ value	0.0961366 (rank : 178)	NC score	0.421975 (rank : 94)
Query Neighborhood Hits	436	Target Neighborhood Hits	209	Shared Neighborhood Hits	144
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI54_MOUSE
θ value	0.0961366 (rank : 179)	NC score	0.420464 (rank : 96)
Query Neighborhood Hits	436	Target Neighborhood Hits	197	Shared Neighborhood Hits	141
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

BICD2_HUMAN
θ value	0.125558 (rank : 180)	NC score	0.043147 (rank : 387)
Query Neighborhood Hits	436	Target Neighborhood Hits	856	Shared Neighborhood Hits	63
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BICD2_MOUSE
θ value	0.125558 (rank : 181)	NC score	0.043098 (rank : 388)
Query Neighborhood Hits	436	Target Neighborhood Hits	864	Shared Neighborhood Hits	65
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

CYLC1_HUMAN
θ value	0.125558 (rank : 182)	NC score	0.071605 (rank : 311)
Query Neighborhood Hits	436	Target Neighborhood Hits	408	Shared Neighborhood Hits	43
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

HMMR_HUMAN
θ value	0.125558 (rank : 183)	NC score	0.036439 (rank : 402)
Query Neighborhood Hits	436	Target Neighborhood Hits	1082	Shared Neighborhood Hits	74
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

NHLC1_MOUSE
θ value	0.125558 (rank : 184)	NC score	0.227941 (rank : 191)
Query Neighborhood Hits	436	Target Neighborhood Hits	103	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

TMCC1_HUMAN
θ value	0.125558 (rank : 185)	NC score	0.042868 (rank : 390)
Query Neighborhood Hits	436	Target Neighborhood Hits	337	Shared Neighborhood Hits	28
SwissProt Accessions	O94876, Q68E06, Q8IXM8	Gene names	TMCC1, KIAA0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

TRAF3_HUMAN
θ value	0.125558 (rank : 186)	NC score	0.228383 (rank : 190)
Query Neighborhood Hits	436	Target Neighborhood Hits	463	Shared Neighborhood Hits	137
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRAF3_MOUSE
θ value	0.125558 (rank : 187)	NC score	0.232205 (rank : 188)
Query Neighborhood Hits	436	Target Neighborhood Hits	476	Shared Neighborhood Hits	140
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

TRIM3_MOUSE
θ value	0.125558 (rank : 188)	NC score	0.398700 (rank : 104)
Query Neighborhood Hits	436	Target Neighborhood Hits	351	Shared Neighborhood Hits	181
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

AFF1_HUMAN
θ value	0.163984 (rank : 189)	NC score	0.057817 (rank : 345)
Query Neighborhood Hits	436	Target Neighborhood Hits	506	Shared Neighborhood Hits	37
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

KCNA4_MOUSE
θ value	0.163984 (rank : 190)	NC score	0.018870 (rank : 471)
Query Neighborhood Hits	436	Target Neighborhood Hits	98	Shared Neighborhood Hits	3
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

TRIM3_HUMAN
θ value	0.163984 (rank : 191)	NC score	0.397455 (rank : 106)
Query Neighborhood Hits	436	Target Neighborhood Hits	357	Shared Neighborhood Hits	184
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

CJ006_MOUSE
θ value	0.21417 (rank : 192)	NC score	0.043076 (rank : 389)
Query Neighborhood Hits	436	Target Neighborhood Hits	141	Shared Neighborhood Hits	18
SwissProt Accessions	Q6P9P0, Q8C041, Q8C0J5	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf6 homolog.

R113B_HUMAN
θ value	0.21417 (rank : 193)	NC score	0.300717 (rank : 141)
Query Neighborhood Hits	436	Target Neighborhood Hits	165	Shared Neighborhood Hits	133
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

RFPL1_HUMAN
θ value	0.21417 (rank : 194)	NC score	0.353111 (rank : 120)
Query Neighborhood Hits	436	Target Neighborhood Hits	119	Shared Neighborhood Hits	92
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

TRI65_HUMAN
θ value	0.21417 (rank : 195)	NC score	0.517187 (rank : 35)
Query Neighborhood Hits	436	Target Neighborhood Hits	330	Shared Neighborhood Hits	194
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI65_MOUSE
θ value	0.21417 (rank : 196)	NC score	0.507185 (rank : 42)
Query Neighborhood Hits	436	Target Neighborhood Hits	340	Shared Neighborhood Hits	191
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

BFAR_HUMAN
θ value	0.279714 (rank : 197)	NC score	0.431804 (rank : 88)
Query Neighborhood Hits	436	Target Neighborhood Hits	222	Shared Neighborhood Hits	161
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

BFAR_MOUSE
θ value	0.279714 (rank : 198)	NC score	0.429379 (rank : 91)
Query Neighborhood Hits	436	Target Neighborhood Hits	232	Shared Neighborhood Hits	157
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

BPTF_HUMAN
θ value	0.279714 (rank : 199)	NC score	0.055556 (rank : 354)
Query Neighborhood Hits	436	Target Neighborhood Hits	786	Shared Neighborhood Hits	79
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BRE1A_HUMAN
θ value	0.279714 (rank : 200)	NC score	0.111980 (rank : 241)
Query Neighborhood Hits	436	Target Neighborhood Hits	1071	Shared Neighborhood Hits	170
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
θ value	0.279714 (rank : 201)	NC score	0.109712 (rank : 245)
Query Neighborhood Hits	436	Target Neighborhood Hits	1025	Shared Neighborhood Hits	158
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

MNAB_HUMAN
θ value	0.279714 (rank : 202)	NC score	0.174015 (rank : 217)
Query Neighborhood Hits	436	Target Neighborhood Hits	196	Shared Neighborhood Hits	105
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

MNAB_MOUSE
θ value	0.279714 (rank : 203)	NC score	0.171836 (rank : 219)
Query Neighborhood Hits	436	Target Neighborhood Hits	231	Shared Neighborhood Hits	104
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

R113A_HUMAN
θ value	0.279714 (rank : 204)	NC score	0.295016 (rank : 144)
Query Neighborhood Hits	436	Target Neighborhood Hits	177	Shared Neighborhood Hits	133
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

RFPL2_HUMAN
θ value	0.279714 (rank : 205)	NC score	0.357490 (rank : 117)
Query Neighborhood Hits	436	Target Neighborhood Hits	126	Shared Neighborhood Hits	98
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

TRAF4_HUMAN
θ value	0.279714 (rank : 206)	NC score	0.262370 (rank : 166)
Query Neighborhood Hits	436	Target Neighborhood Hits	373	Shared Neighborhood Hits	149
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

TRAF5_HUMAN
θ value	0.279714 (rank : 207)	NC score	0.248351 (rank : 177)
Query Neighborhood Hits	436	Target Neighborhood Hits	396	Shared Neighborhood Hits	134
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

WNK1_HUMAN
θ value	0.279714 (rank : 208)	NC score	0.004503 (rank : 528)
Query Neighborhood Hits	436	Target Neighborhood Hits	1158	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

APC_HUMAN
θ value	0.365318 (rank : 209)	NC score	0.044388 (rank : 383)
Query Neighborhood Hits	436	Target Neighborhood Hits	603	Shared Neighborhood Hits	59
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

BRE1B_HUMAN
θ value	0.365318 (rank : 210)	NC score	0.124367 (rank : 233)
Query Neighborhood Hits	436	Target Neighborhood Hits	1040	Shared Neighborhood Hits	177
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
θ value	0.365318 (rank : 211)	NC score	0.126248 (rank : 232)
Query Neighborhood Hits	436	Target Neighborhood Hits	970	Shared Neighborhood Hits	166
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

HIP1_HUMAN
θ value	0.365318 (rank : 212)	NC score	0.029968 (rank : 424)
Query Neighborhood Hits	436	Target Neighborhood Hits	1016	Shared Neighborhood Hits	68
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

MYRIP_HUMAN
θ value	0.365318 (rank : 213)	NC score	0.039106 (rank : 399)
Query Neighborhood Hits	436	Target Neighborhood Hits	269	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

OSTP_MOUSE
θ value	0.365318 (rank : 214)	NC score	0.062193 (rank : 332)
Query Neighborhood Hits	436	Target Neighborhood Hits	60	Shared Neighborhood Hits	17
SwissProt Accessions	P10923, P19008	Gene names	Spp1, Eta-1, Op, Spp-1
Domain Architecture
Description	Osteopontin precursor (Bone sialoprotein-1) (Secreted phosphoprotein 1) (SPP-1) (Minopontin) (Early T-lymphocyte activation 1 protein) (2AR) (Calcium oxalate crystal growth inhibitor protein).

SYTL5_HUMAN
θ value	0.365318 (rank : 215)	NC score	0.021122 (rank : 461)
Query Neighborhood Hits	436	Target Neighborhood Hits	237	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

UBF1_HUMAN
θ value	0.365318 (rank : 216)	NC score	0.035853 (rank : 405)
Query Neighborhood Hits	436	Target Neighborhood Hits	415	Shared Neighborhood Hits	29
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

UBP53_MOUSE
θ value	0.365318 (rank : 217)	NC score	0.035834 (rank : 406)
Query Neighborhood Hits	436	Target Neighborhood Hits	188	Shared Neighborhood Hits	23
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

APC11_MOUSE
θ value	0.47712 (rank : 218)	NC score	0.081584 (rank : 285)
Query Neighborhood Hits	436	Target Neighborhood Hits	75	Shared Neighborhood Hits	22
SwissProt Accessions	Q9CPX9, Q3UWH1, Q9CTG0	Gene names	Anapc11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11).

ATRX_MOUSE
θ value	0.47712 (rank : 219)	NC score	0.070602 (rank : 314)
Query Neighborhood Hits	436	Target Neighborhood Hits	682	Shared Neighborhood Hits	80
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

CBLC_HUMAN
θ value	0.47712 (rank : 220)	NC score	0.185103 (rank : 212)
Query Neighborhood Hits	436	Target Neighborhood Hits	173	Shared Neighborhood Hits	115
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

GAK_HUMAN
θ value	0.47712 (rank : 221)	NC score	0.002402 (rank : 536)
Query Neighborhood Hits	436	Target Neighborhood Hits	1028	Shared Neighborhood Hits	24
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

HIRP3_HUMAN
θ value	0.47712 (rank : 222)	NC score	0.070495 (rank : 315)
Query Neighborhood Hits	436	Target Neighborhood Hits	323	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

PCX1_HUMAN
θ value	0.47712 (rank : 223)	NC score	0.040697 (rank : 395)
Query Neighborhood Hits	436	Target Neighborhood Hits	102	Shared Neighborhood Hits	14
SwissProt Accessions	Q96RV3, O94897, Q96AI7, Q9Y2J9	Gene names	PCNX, KIAA0805, KIAA0995, PCNXL1
Domain Architecture
Description	Pecanex-like protein 1 (Pecanex homolog).

PHF14_HUMAN
θ value	0.47712 (rank : 224)	NC score	0.054261 (rank : 356)
Query Neighborhood Hits	436	Target Neighborhood Hits	447	Shared Neighborhood Hits	45
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

RAD17_HUMAN
θ value	0.47712 (rank : 225)	NC score	0.035856 (rank : 404)
Query Neighborhood Hits	436	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	O75943, O75714, Q7Z3S4, Q9UNK7, Q9UNR7, Q9UNR8, Q9UPF5	Gene names	RAD17, R24L
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint protein RAD17 (hRad17) (RF-C/activator 1 homolog).

RFPL3_HUMAN
θ value	0.47712 (rank : 226)	NC score	0.364989 (rank : 112)
Query Neighborhood Hits	436	Target Neighborhood Hits	134	Shared Neighborhood Hits	104
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

SRRM1_HUMAN
θ value	0.47712 (rank : 227)	NC score	0.058591 (rank : 342)
Query Neighborhood Hits	436	Target Neighborhood Hits	690	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
θ value	0.47712 (rank : 228)	NC score	0.060108 (rank : 336)
Query Neighborhood Hits	436	Target Neighborhood Hits	966	Shared Neighborhood Hits	63
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SYNP2_MOUSE
θ value	0.47712 (rank : 229)	NC score	0.023651 (rank : 446)
Query Neighborhood Hits	436	Target Neighborhood Hits	252	Shared Neighborhood Hits	16
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

TRI36_MOUSE
θ value	0.47712 (rank : 230)	NC score	0.307848 (rank : 137)
Query Neighborhood Hits	436	Target Neighborhood Hits	266	Shared Neighborhood Hits	138
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

ATX3_HUMAN
θ value	0.62314 (rank : 231)	NC score	0.039967 (rank : 397)
Query Neighborhood Hits	436	Target Neighborhood Hits	117	Shared Neighborhood Hits	9
SwissProt Accessions	P54252, O15284, O15285, O15286, Q8N189, Q96TC3, Q96TC4, Q9H3N0	Gene names	ATXN3, ATX3, MJD, MJD1, SCA3
Domain Architecture
Description	Ataxin-3 (EC 3.4.22.-) (Machado-Joseph disease protein 1) (Spinocerebellar ataxia type 3 protein).

COEA1_MOUSE
θ value	0.62314 (rank : 232)	NC score	0.008080 (rank : 516)
Query Neighborhood Hits	436	Target Neighborhood Hits	402	Shared Neighborhood Hits	11
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

DNMT1_HUMAN
θ value	0.62314 (rank : 233)	NC score	0.049280 (rank : 371)
Query Neighborhood Hits	436	Target Neighborhood Hits	401	Shared Neighborhood Hits	53
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

HTSF1_HUMAN
θ value	0.62314 (rank : 234)	NC score	0.048379 (rank : 372)
Query Neighborhood Hits	436	Target Neighborhood Hits	408	Shared Neighborhood Hits	35
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

LRSM1_MOUSE
θ value	0.62314 (rank : 235)	NC score	0.071902 (rank : 310)
Query Neighborhood Hits	436	Target Neighborhood Hits	874	Shared Neighborhood Hits	108
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

PSIP1_HUMAN
θ value	0.62314 (rank : 236)	NC score	0.042824 (rank : 391)
Query Neighborhood Hits	436	Target Neighborhood Hits	341	Shared Neighborhood Hits	35
SwissProt Accessions	O75475, O00256, O95368, Q6P391, Q86YB9, Q9NZI3, Q9UER6	Gene names	PSIP1, DFS70, LEDGF, PSIP2
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52) (Dense fine speckles 70 kDa protein) (DFS 70) (CLL-associated antigen KW-7).

SN1L1_MOUSE
θ value	0.62314 (rank : 237)	NC score	-0.002931 (rank : 546)
Query Neighborhood Hits	436	Target Neighborhood Hits	895	Shared Neighborhood Hits	23
SwissProt Accessions	Q60670	Gene names	Snf1lk, Msk
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1- like kinase).

BIRC7_HUMAN
θ value	0.813845 (rank : 238)	NC score	0.238307 (rank : 184)
Query Neighborhood Hits	436	Target Neighborhood Hits	185	Shared Neighborhood Hits	140
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

CHD8_HUMAN
θ value	0.813845 (rank : 239)	NC score	0.033925 (rank : 411)
Query Neighborhood Hits	436	Target Neighborhood Hits	235	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

DHX36_HUMAN
θ value	0.813845 (rank : 240)	NC score	0.014599 (rank : 492)
Query Neighborhood Hits	436	Target Neighborhood Hits	63	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H2U1, Q70JU3, Q8IYE5, Q9P240	Gene names	DHX36, DDX36, KIAA1488, MLEL1, RHAU
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

IF2P_HUMAN
θ value	0.813845 (rank : 241)	NC score	0.045355 (rank : 380)
Query Neighborhood Hits	436	Target Neighborhood Hits	889	Shared Neighborhood Hits	66
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

PIAS3_MOUSE
θ value	0.813845 (rank : 242)	NC score	0.019082 (rank : 470)
Query Neighborhood Hits	436	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	O54714, Q80WF8, Q8R598	Gene names	Pias3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

RABE2_MOUSE
θ value	0.813845 (rank : 243)	NC score	0.033198 (rank : 414)
Query Neighborhood Hits	436	Target Neighborhood Hits	598	Shared Neighborhood Hits	47
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

RP1L1_HUMAN
θ value	0.813845 (rank : 244)	NC score	0.052093 (rank : 363)
Query Neighborhood Hits	436	Target Neighborhood Hits	1072	Shared Neighborhood Hits	76
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

TRI36_HUMAN
θ value	0.813845 (rank : 245)	NC score	0.310772 (rank : 135)
Query Neighborhood Hits	436	Target Neighborhood Hits	282	Shared Neighborhood Hits	141
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

CF096_HUMAN
θ value	1.06291 (rank : 246)	NC score	0.028786 (rank : 427)
Query Neighborhood Hits	436	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NWS8, Q5SZ48, Q5SZ83, Q6NSC5, Q96EN7	Gene names	C6orf96
Domain Architecture	No domain graphic available
Description	Protein C6orf96.

CHD1_HUMAN
θ value	1.06291 (rank : 247)	NC score	0.043302 (rank : 385)
Query Neighborhood Hits	436	Target Neighborhood Hits	337	Shared Neighborhood Hits	35
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHFR_HUMAN
θ value	1.06291 (rank : 248)	NC score	0.336926 (rank : 121)
Query Neighborhood Hits	436	Target Neighborhood Hits	255	Shared Neighborhood Hits	161
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_MOUSE
θ value	1.06291 (rank : 249)	NC score	0.336582 (rank : 122)
Query Neighborhood Hits	436	Target Neighborhood Hits	264	Shared Neighborhood Hits	166
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

EMAL4_HUMAN
θ value	1.06291 (rank : 250)	NC score	0.024554 (rank : 443)
Query Neighborhood Hits	436	Target Neighborhood Hits	306	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HC35	Gene names	EML4, C2orf2, EMAPL4
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 4 (EMAP-4) (Restrictedly overexpressed proliferation-associated protein) (Ropp 120).

EP15_HUMAN
θ value	1.06291 (rank : 251)	NC score	0.045127 (rank : 381)
Query Neighborhood Hits	436	Target Neighborhood Hits	1021	Shared Neighborhood Hits	66
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

GASP1_MOUSE
θ value	1.06291 (rank : 252)	NC score	0.027383 (rank : 431)
Query Neighborhood Hits	436	Target Neighborhood Hits	169	Shared Neighborhood Hits	28
SwissProt Accessions	Q5U4C1, Q8BKR8, Q8BUN4, Q8BYK9, Q8CHF4, Q8R095	Gene names	Gprasp1, Kiaa0443
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 1 (GASP-1).

IASPP_HUMAN
θ value	1.06291 (rank : 253)	NC score	0.023300 (rank : 447)
Query Neighborhood Hits	436	Target Neighborhood Hits	688	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

K0408_HUMAN
θ value	1.06291 (rank : 254)	NC score	0.043217 (rank : 386)
Query Neighborhood Hits	436	Target Neighborhood Hits	101	Shared Neighborhood Hits	16
SwissProt Accessions	Q6ZU52, O43158, Q5TF20, Q7L2M2	Gene names	KIAA0408
Domain Architecture	No domain graphic available
Description	Protein KIAA0408.

MKRN4_HUMAN
θ value	1.06291 (rank : 255)	NC score	0.099150 (rank : 263)
Query Neighborhood Hits	436	Target Neighborhood Hits	147	Shared Neighborhood Hits	79
SwissProt Accessions	Q13434	Gene names	MKRN4, RNF64, ZNF127L1
Domain Architecture	No domain graphic available
Description	Makorin-4 (Zinc finger protein 127-Xp) (ZNF127-Xp) (RING finger protein 64).

RFIP1_HUMAN
θ value	1.06291 (rank : 256)	NC score	0.029356 (rank : 425)
Query Neighborhood Hits	436	Target Neighborhood Hits	236	Shared Neighborhood Hits	17
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

SLK_MOUSE
θ value	1.06291 (rank : 257)	NC score	0.008870 (rank : 512)
Query Neighborhood Hits	436	Target Neighborhood Hits	1798	Shared Neighborhood Hits	105
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

ULK1_MOUSE
θ value	1.06291 (rank : 258)	NC score	-0.001914 (rank : 545)
Query Neighborhood Hits	436	Target Neighborhood Hits	1214	Shared Neighborhood Hits	36
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

AFF1_MOUSE
θ value	1.38821 (rank : 259)	NC score	0.052787 (rank : 359)
Query Neighborhood Hits	436	Target Neighborhood Hits	351	Shared Neighborhood Hits	33
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

AFF3_HUMAN
θ value	1.38821 (rank : 260)	NC score	0.047076 (rank : 376)
Query Neighborhood Hits	436	Target Neighborhood Hits	190	Shared Neighborhood Hits	32
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

AMPH_MOUSE
θ value	1.38821 (rank : 261)	NC score	0.023078 (rank : 449)
Query Neighborhood Hits	436	Target Neighborhood Hits	291	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

CSPG2_HUMAN
θ value	1.38821 (rank : 262)	NC score	0.003821 (rank : 531)
Query Neighborhood Hits	436	Target Neighborhood Hits	681	Shared Neighborhood Hits	19
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

IF4G3_HUMAN
θ value	1.38821 (rank : 263)	NC score	0.019116 (rank : 469)
Query Neighborhood Hits	436	Target Neighborhood Hits	247	Shared Neighborhood Hits	22
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

MIB2_HUMAN
θ value	1.38821 (rank : 264)	NC score	0.083574 (rank : 279)
Query Neighborhood Hits	436	Target Neighborhood Hits	438	Shared Neighborhood Hits	90
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

MYH4_HUMAN
θ value	1.38821 (rank : 265)	NC score	0.020449 (rank : 464)
Query Neighborhood Hits	436	Target Neighborhood Hits	1377	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

AKA12_HUMAN
θ value	1.81305 (rank : 266)	NC score	0.075546 (rank : 298)
Query Neighborhood Hits	436	Target Neighborhood Hits	825	Shared Neighborhood Hits	97
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

APC11_HUMAN
θ value	1.81305 (rank : 267)	NC score	0.067421 (rank : 321)
Query Neighborhood Hits	436	Target Neighborhood Hits	74	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NYG5, Q502X9, Q9BW64, Q9P0R2	Gene names	ANAPC11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11) (Hepatocellular carcinoma-associated RING finger protein).

CCNB3_MOUSE
θ value	1.81305 (rank : 268)	NC score	0.018469 (rank : 472)
Query Neighborhood Hits	436	Target Neighborhood Hits	211	Shared Neighborhood Hits	21
SwissProt Accessions	Q810T2, Q810T3, Q8VDC8	Gene names	Ccnb3, Cycb3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

CHK2_HUMAN
θ value	1.81305 (rank : 269)	NC score	-0.003526 (rank : 548)
Query Neighborhood Hits	436	Target Neighborhood Hits	859	Shared Neighborhood Hits	17
SwissProt Accessions	O96017, Q6QA03, Q6QA04, Q6QA05, Q6QA06, Q6QA07, Q6QA08, Q6QA10, Q6QA11, Q6QA12, Q6QA13, Q9HCQ8, Q9UGF0, Q9UGF1	Gene names	CHEK2, CHK2
Domain Architecture
Description	Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (Cds1).

E2F5_MOUSE
θ value	1.81305 (rank : 270)	NC score	0.016067 (rank : 482)
Query Neighborhood Hits	436	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q61502	Gene names	E2f5
Domain Architecture
Description	Transcription factor E2F5 (E2F-5).

LRSM1_HUMAN
θ value	1.81305 (rank : 271)	NC score	0.074670 (rank : 302)
Query Neighborhood Hits	436	Target Neighborhood Hits	1078	Shared Neighborhood Hits	127
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

MICA3_HUMAN
θ value	1.81305 (rank : 272)	NC score	0.008095 (rank : 515)
Query Neighborhood Hits	436	Target Neighborhood Hits	160	Shared Neighborhood Hits	6
SwissProt Accessions	Q7RTP6, Q6ICK4, Q9P2I3	Gene names	MICAL3, KIAA1364
Domain Architecture
Description	Protein MICAL-3.

NPAS2_HUMAN
θ value	1.81305 (rank : 273)	NC score	0.010432 (rank : 507)
Query Neighborhood Hits	436	Target Neighborhood Hits	150	Shared Neighborhood Hits	8
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

PHF14_MOUSE
θ value	1.81305 (rank : 274)	NC score	0.053845 (rank : 358)
Query Neighborhood Hits	436	Target Neighborhood Hits	342	Shared Neighborhood Hits	48
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

PO121_HUMAN
θ value	1.81305 (rank : 275)	NC score	0.030008 (rank : 423)
Query Neighborhood Hits	436	Target Neighborhood Hits	344	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PPIG_HUMAN
θ value	1.81305 (rank : 276)	NC score	0.032838 (rank : 416)
Query Neighborhood Hits	436	Target Neighborhood Hits	670	Shared Neighborhood Hits	70
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

SRCA_HUMAN
θ value	1.81305 (rank : 277)	NC score	0.029162 (rank : 426)
Query Neighborhood Hits	436	Target Neighborhood Hits	380	Shared Neighborhood Hits	36
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

TARA_HUMAN
θ value	1.81305 (rank : 278)	NC score	0.067449 (rank : 320)
Query Neighborhood Hits	436	Target Neighborhood Hits	1626	Shared Neighborhood Hits	123
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TBC14_HUMAN
θ value	1.81305 (rank : 279)	NC score	0.021218 (rank : 460)
Query Neighborhood Hits	436	Target Neighborhood Hits	124	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P2M4, Q8IW15	Gene names	TBC1D14, KIAA1322
Domain Architecture
Description	TBC1 domain family member 14.

TOPRS_HUMAN
θ value	1.81305 (rank : 280)	NC score	0.234744 (rank : 186)
Query Neighborhood Hits	436	Target Neighborhood Hits	286	Shared Neighborhood Hits	135
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	1.81305 (rank : 281)	NC score	0.235427 (rank : 185)
Query Neighborhood Hits	436	Target Neighborhood Hits	263	Shared Neighborhood Hits	131
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

ATS19_MOUSE
θ value	2.36792 (rank : 282)	NC score	0.002752 (rank : 532)
Query Neighborhood Hits	436	Target Neighborhood Hits	188	Shared Neighborhood Hits	6
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

CBLB_HUMAN
θ value	2.36792 (rank : 283)	NC score	0.160100 (rank : 225)
Query Neighborhood Hits	436	Target Neighborhood Hits	261	Shared Neighborhood Hits	130
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
θ value	2.36792 (rank : 284)	NC score	0.160814 (rank : 224)
Query Neighborhood Hits	436	Target Neighborhood Hits	277	Shared Neighborhood Hits	131
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CBL_HUMAN
θ value	2.36792 (rank : 285)	NC score	0.172023 (rank : 218)
Query Neighborhood Hits	436	Target Neighborhood Hits	353	Shared Neighborhood Hits	149
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBL_MOUSE
θ value	2.36792 (rank : 286)	NC score	0.170745 (rank : 220)
Query Neighborhood Hits	436	Target Neighborhood Hits	426	Shared Neighborhood Hits	153
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

DEK_HUMAN
θ value	2.36792 (rank : 287)	NC score	0.050022 (rank : 369)
Query Neighborhood Hits	436	Target Neighborhood Hits	199	Shared Neighborhood Hits	31
SwissProt Accessions	P35659, Q5TGV4, Q5TGV5	Gene names	DEK
Domain Architecture	No domain graphic available
Description	Protein DEK.

DHX36_MOUSE
θ value	2.36792 (rank : 288)	NC score	0.012456 (rank : 502)
Query Neighborhood Hits	436	Target Neighborhood Hits	114	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

EP15_MOUSE
θ value	2.36792 (rank : 289)	NC score	0.041866 (rank : 394)
Query Neighborhood Hits	436	Target Neighborhood Hits	820	Shared Neighborhood Hits	49
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

MDC1_HUMAN
θ value	2.36792 (rank : 290)	NC score	0.052175 (rank : 361)
Query Neighborhood Hits	436	Target Neighborhood Hits	1446	Shared Neighborhood Hits	103
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MDC1_MOUSE
θ value	2.36792 (rank : 291)	NC score	0.047333 (rank : 375)
Query Neighborhood Hits	436	Target Neighborhood Hits	998	Shared Neighborhood Hits	74
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MIB2_MOUSE
θ value	2.36792 (rank : 292)	NC score	0.076830 (rank : 295)
Query Neighborhood Hits	436	Target Neighborhood Hits	409	Shared Neighborhood Hits	83
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

MYT1_HUMAN
θ value	2.36792 (rank : 293)	NC score	0.020582 (rank : 463)
Query Neighborhood Hits	436	Target Neighborhood Hits	475	Shared Neighborhood Hits	41
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

PEX2_HUMAN
θ value	2.36792 (rank : 294)	NC score	0.090231 (rank : 273)
Query Neighborhood Hits	436	Target Neighborhood Hits	42	Shared Neighborhood Hits	35
SwissProt Accessions	P28328, Q567S6, Q9BW41	Gene names	PXMP3, PAF1, PEX2, PMP3, PMP35, RNF72
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3) (35 kDa peroxisomal membrane protein) (RING finger protein 72).

PP4R1_HUMAN
θ value	2.36792 (rank : 295)	NC score	0.017338 (rank : 478)
Query Neighborhood Hits	436	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TF05, Q99774, Q9UNQ7	Gene names	PPP4R1, MEG1, PP4R1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

PRP4B_HUMAN
θ value	2.36792 (rank : 296)	NC score	0.010998 (rank : 504)
Query Neighborhood Hits	436	Target Neighborhood Hits	1030	Shared Neighborhood Hits	54
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

RERE_HUMAN
θ value	2.36792 (rank : 297)	NC score	0.023287 (rank : 448)
Query Neighborhood Hits	436	Target Neighborhood Hits	779	Shared Neighborhood Hits	36
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RFFL_HUMAN
θ value	2.36792 (rank : 298)	NC score	0.086838 (rank : 277)
Query Neighborhood Hits	436	Target Neighborhood Hits	175	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

TBC12_HUMAN
θ value	2.36792 (rank : 299)	NC score	0.021507 (rank : 459)
Query Neighborhood Hits	436	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	O60347, Q5VYA6, Q8WX26, Q8WX59, Q9UG83	Gene names	TBC1D12, KIAA0608
Domain Architecture
Description	TBC1 domain family member 12.

TRAF5_MOUSE
θ value	2.36792 (rank : 300)	NC score	0.258060 (rank : 174)
Query Neighborhood Hits	436	Target Neighborhood Hits	355	Shared Neighborhood Hits	141
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

TTLL5_HUMAN
θ value	2.36792 (rank : 301)	NC score	0.015336 (rank : 488)
Query Neighborhood Hits	436	Target Neighborhood Hits	141	Shared Neighborhood Hits	16
SwissProt Accessions	Q6EMB2, Q9P1V5, Q9UPZ4	Gene names	TTLL5, KIAA0998, STAMP
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5 (SRC1 and TIF2-associated modulatory protein).

CD19_MOUSE
θ value	3.0926 (rank : 302)	NC score	0.020367 (rank : 465)
Query Neighborhood Hits	436	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	P25918	Gene names	Cd19
Domain Architecture
Description	B-lymphocyte antigen CD19 precursor (Differentiation antigen CD19).

DAXX_MOUSE
θ value	3.0926 (rank : 303)	NC score	0.033820 (rank : 412)
Query Neighborhood Hits	436	Target Neighborhood Hits	173	Shared Neighborhood Hits	21
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

DTX2_HUMAN
θ value	3.0926 (rank : 304)	NC score	0.046390 (rank : 379)
Query Neighborhood Hits	436	Target Neighborhood Hits	84	Shared Neighborhood Hits	14
SwissProt Accessions	Q86UW9, Q96H69, Q9H890, Q9P200	Gene names	DTX2, KIAA1528
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (hDTX2).

DTX2_MOUSE
θ value	3.0926 (rank : 305)	NC score	0.046710 (rank : 377)
Query Neighborhood Hits	436	Target Neighborhood Hits	76	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R3P2, Q9CZV3, Q9ER07, Q9ER08	Gene names	Dtx2
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (mDTX2).

DTX3L_HUMAN
θ value	3.0926 (rank : 306)	NC score	0.202662 (rank : 200)
Query Neighborhood Hits	436	Target Neighborhood Hits	187	Shared Neighborhood Hits	117
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

FYCO1_MOUSE
θ value	3.0926 (rank : 307)	NC score	0.021570 (rank : 458)
Query Neighborhood Hits	436	Target Neighborhood Hits	1059	Shared Neighborhood Hits	61
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

GP149_HUMAN
θ value	3.0926 (rank : 308)	NC score	0.017692 (rank : 477)
Query Neighborhood Hits	436	Target Neighborhood Hits	68	Shared Neighborhood Hits	4
SwissProt Accessions	Q86SP6	Gene names	GPR149, PGR10
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 149 (G-protein coupled receptor PGR10).

HIPK3_MOUSE
θ value	3.0926 (rank : 309)	NC score	-0.000186 (rank : 544)
Query Neighborhood Hits	436	Target Neighborhood Hits	857	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ERH7, O88906, Q9QZR2	Gene names	Hipk3, Fist3
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Fas- interacting serine/threonine-protein kinase) (FIST) (Nuclear body- associated kinase 3) (Nbak3) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

K0460_HUMAN
θ value	3.0926 (rank : 310)	NC score	0.025108 (rank : 440)
Query Neighborhood Hits	436	Target Neighborhood Hits	357	Shared Neighborhood Hits	37
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

MPP10_MOUSE
θ value	3.0926 (rank : 311)	NC score	0.022112 (rank : 455)
Query Neighborhood Hits	436	Target Neighborhood Hits	251	Shared Neighborhood Hits	20
SwissProt Accessions	Q810V0	Gene names	Mphosph10
Domain Architecture	No domain graphic available
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

MYST3_HUMAN
θ value	3.0926 (rank : 312)	NC score	0.032060 (rank : 418)
Query Neighborhood Hits	436	Target Neighborhood Hits	772	Shared Neighborhood Hits	63
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

NEDD1_MOUSE
θ value	3.0926 (rank : 313)	NC score	0.018046 (rank : 476)
Query Neighborhood Hits	436	Target Neighborhood Hits	281	Shared Neighborhood Hits	17
SwissProt Accessions	P33215, Q6NXV3, Q8BN12, Q8BN86, Q8BQL9, Q9CWK2	Gene names	Nedd1, Nedd-1
Domain Architecture	No domain graphic available
Description	Protein NEDD1 (Neural precursor cell expressed developmentally down- regulated protein 1).

PCGF2_HUMAN
θ value	3.0926 (rank : 314)	NC score	0.202401 (rank : 201)
Query Neighborhood Hits	436	Target Neighborhood Hits	222	Shared Neighborhood Hits	112
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
θ value	3.0926 (rank : 315)	NC score	0.201869 (rank : 202)
Query Neighborhood Hits	436	Target Neighborhood Hits	213	Shared Neighborhood Hits	110
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PDE4A_HUMAN
θ value	3.0926 (rank : 316)	NC score	0.004408 (rank : 529)
Query Neighborhood Hits	436	Target Neighborhood Hits	73	Shared Neighborhood Hits	3
SwissProt Accessions	P27815, O75522, O76092, Q16255, Q16691, Q8WUQ3	Gene names	PDE4A
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4A (EC 3.1.4.17) (DPDE2) (PDE46).

PHF20_MOUSE
θ value	3.0926 (rank : 317)	NC score	0.042328 (rank : 392)
Query Neighborhood Hits	436	Target Neighborhood Hits	513	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PHF3_HUMAN
θ value	3.0926 (rank : 318)	NC score	0.028643 (rank : 428)
Query Neighborhood Hits	436	Target Neighborhood Hits	419	Shared Neighborhood Hits	31
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

PML_MOUSE
θ value	3.0926 (rank : 319)	NC score	0.198624 (rank : 205)
Query Neighborhood Hits	436	Target Neighborhood Hits	246	Shared Neighborhood Hits	122
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

SIA1A_MOUSE
θ value	3.0926 (rank : 320)	NC score	0.122092 (rank : 236)
Query Neighborhood Hits	436	Target Neighborhood Hits	72	Shared Neighborhood Hits	53
SwissProt Accessions	P61092, Q06984	Gene names	Siah1a
Domain Architecture
Description	Ubiquitin ligase SIAH1A (EC 6.3.2.-) (Seven in absentia homolog 1a) (Siah1a) (Siah-1a) (mSiah-1a).

SIA1B_MOUSE
θ value	3.0926 (rank : 321)	NC score	0.123485 (rank : 234)
Query Neighborhood Hits	436	Target Neighborhood Hits	69	Shared Neighborhood Hits	52
SwissProt Accessions	Q06985, Q7TPV6	Gene names	Siah1b
Domain Architecture
Description	Ubiquitin ligase SIAH1B (EC 6.3.2.-) (Seven in absentia homolog 1b) (Siah1b) (Siah-1b).

SIAH1_HUMAN
θ value	3.0926 (rank : 322)	NC score	0.122830 (rank : 235)
Query Neighborhood Hits	436	Target Neighborhood Hits	72	Shared Neighborhood Hits	53
SwissProt Accessions	Q8IUQ4, O43269, Q92880	Gene names	SIAH1, HUMSIAH
Domain Architecture
Description	Ubiquitin ligase SIAH1 (EC 6.3.2.-) (Seven in absentia homolog 1) (Siah-1) (Siah-1a).

TCPH_MOUSE
θ value	3.0926 (rank : 323)	NC score	0.006871 (rank : 521)
Query Neighborhood Hits	436	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	P80313	Gene names	Cct7, Ccth
Domain Architecture
Description	T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta).

TRI45_MOUSE
θ value	3.0926 (rank : 324)	NC score	0.185450 (rank : 211)
Query Neighborhood Hits	436	Target Neighborhood Hits	155	Shared Neighborhood Hits	86
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

ARI1B_HUMAN
θ value	4.03905 (rank : 325)	NC score	0.022072 (rank : 456)
Query Neighborhood Hits	436	Target Neighborhood Hits	567	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

CD45_HUMAN
θ value	4.03905 (rank : 326)	NC score	0.004287 (rank : 530)
Query Neighborhood Hits	436	Target Neighborhood Hits	243	Shared Neighborhood Hits	15
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

CDN1C_MOUSE
θ value	4.03905 (rank : 327)	NC score	0.024812 (rank : 442)
Query Neighborhood Hits	436	Target Neighborhood Hits	161	Shared Neighborhood Hits	16
SwissProt Accessions	P49919	Gene names	Cdkn1c, Kip2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CKAP2_HUMAN
θ value	4.03905 (rank : 328)	NC score	0.024191 (rank : 444)
Query Neighborhood Hits	436	Target Neighborhood Hits	116	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WWK9, Q3KRA5, Q5VXB4, Q8IWV5, Q8IWV6, Q96FH9, Q9H012, Q9H0D0, Q9H988, Q9HC49, Q9NVG4	Gene names	CKAP2, LB1, TMAP
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 2 (Tumor-associated microtubule- associated protein) (CTCL tumor antigen se20-10).

DDX54_MOUSE
θ value	4.03905 (rank : 329)	NC score	0.002135 (rank : 539)
Query Neighborhood Hits	436	Target Neighborhood Hits	124	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DNL3_MOUSE
θ value	4.03905 (rank : 330)	NC score	0.013205 (rank : 496)
Query Neighborhood Hits	436	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	P97386, P97385	Gene names	Lig3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

H13_MOUSE
θ value	4.03905 (rank : 331)	NC score	0.012619 (rank : 499)
Query Neighborhood Hits	436	Target Neighborhood Hits	81	Shared Neighborhood Hits	9
SwissProt Accessions	P43277, Q8C6M4	Gene names	Hist1h1d, H1f3
Domain Architecture
Description	Histone H1.3 (H1 VAR.4) (H1d).

HEMGN_HUMAN
θ value	4.03905 (rank : 332)	NC score	0.027230 (rank : 433)
Query Neighborhood Hits	436	Target Neighborhood Hits	92	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BXL5, Q6XAR3, Q86XY5, Q9NPC0	Gene names	HEMGN, EDAG, NDR
Domain Architecture	No domain graphic available
Description	Hemogen (Hemopoietic gene protein) (Negative differentiation regulator protein) (Erythroid differentiation-associated gene protein) (EDAG-1).

MKRN1_HUMAN
θ value	4.03905 (rank : 333)	NC score	0.081025 (rank : 286)
Query Neighborhood Hits	436	Target Neighborhood Hits	141	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UHC7, Q6GSF1, Q9H0G0, Q9UEZ7	Gene names	MKRN1, RNF61
Domain Architecture
Description	Makorin-1 (RING finger protein 61).

MKRN1_MOUSE
θ value	4.03905 (rank : 334)	NC score	0.078099 (rank : 292)
Query Neighborhood Hits	436	Target Neighborhood Hits	141	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QXP6	Gene names	Mkrn1
Domain Architecture
Description	Makorin-1.

NFAT5_HUMAN
θ value	4.03905 (rank : 335)	NC score	0.014179 (rank : 493)
Query Neighborhood Hits	436	Target Neighborhood Hits	217	Shared Neighborhood Hits	9
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

NOL10_HUMAN
θ value	4.03905 (rank : 336)	NC score	0.022776 (rank : 450)
Query Neighborhood Hits	436	Target Neighborhood Hits	254	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BSC4, Q53RC9, Q96TA5, Q9H7Y7, Q9H855	Gene names	NOL10
Domain Architecture	No domain graphic available
Description	Nucleolar protein 10.

NOP56_MOUSE
θ value	4.03905 (rank : 337)	NC score	0.022636 (rank : 451)
Query Neighborhood Hits	436	Target Neighborhood Hits	129	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D6Z1, Q3UD45, Q8BVL1, Q8VDT2, Q99LT8, Q9CT15	Gene names	Nol5a, Nop56
Domain Architecture
Description	Nucleolar protein Nop56 (Nucleolar protein 5A).

PIAS3_HUMAN
θ value	4.03905 (rank : 338)	NC score	0.014991 (rank : 490)
Query Neighborhood Hits	436	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6X2, Q9UFI3	Gene names	PIAS3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

RBM25_HUMAN
θ value	4.03905 (rank : 339)	NC score	0.027163 (rank : 434)
Query Neighborhood Hits	436	Target Neighborhood Hits	682	Shared Neighborhood Hits	49
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

RSF1_HUMAN
θ value	4.03905 (rank : 340)	NC score	0.063277 (rank : 329)
Query Neighborhood Hits	436	Target Neighborhood Hits	539	Shared Neighborhood Hits	62
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SH2D3_MOUSE
θ value	4.03905 (rank : 341)	NC score	0.008522 (rank : 514)
Query Neighborhood Hits	436	Target Neighborhood Hits	174	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QZS8, Q9JME1	Gene names	Sh2d3c, Chat, Shep1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (SH2 domain-containing Eph receptor- binding protein 1) (Cas/HEF1-associated signal transducer).

SUHW4_MOUSE
θ value	4.03905 (rank : 342)	NC score	0.000700 (rank : 543)
Query Neighborhood Hits	436	Target Neighborhood Hits	737	Shared Neighborhood Hits	19
SwissProt Accessions	Q68FE8, Q3T9B1, Q8BI82	Gene names	Suhw4
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

TIAM1_HUMAN
θ value	4.03905 (rank : 343)	NC score	0.010805 (rank : 505)
Query Neighborhood Hits	436	Target Neighborhood Hits	225	Shared Neighborhood Hits	12
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TOIP1_HUMAN
θ value	4.03905 (rank : 344)	NC score	0.025627 (rank : 437)
Query Neighborhood Hits	436	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q5JTV8, Q5JTV6, Q8IZ65, Q9H8Y6, Q9HAJ1, Q9NV52, Q9Y3X5	Gene names	TOR1AIP1
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 1.

YTDC1_HUMAN
θ value	4.03905 (rank : 345)	NC score	0.052437 (rank : 360)
Query Neighborhood Hits	436	Target Neighborhood Hits	458	Shared Neighborhood Hits	65
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

ZN198_HUMAN
θ value	4.03905 (rank : 346)	NC score	0.015983 (rank : 484)
Query Neighborhood Hits	436	Target Neighborhood Hits	128	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UBW7, O43212, O43434, O60898, Q5W0Q4, Q63HP0, Q8NE39, Q9H538, Q9UEU2	Gene names	ZNF198, FIM, RAMP, ZMYM2
Domain Architecture
Description	Zinc finger protein 198 (Zinc finger MYM-type protein 2) (Fused in myeloproliferative disorders protein) (Rearranged in atypical myeloproliferative disorder protein).

AKAP6_HUMAN
θ value	5.27518 (rank : 347)	NC score	0.024906 (rank : 441)
Query Neighborhood Hits	436	Target Neighborhood Hits	263	Shared Neighborhood Hits	37
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

AP3B1_HUMAN
θ value	5.27518 (rank : 348)	NC score	0.022581 (rank : 452)
Query Neighborhood Hits	436	Target Neighborhood Hits	283	Shared Neighborhood Hits	37
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

ASIP_MOUSE
θ value	5.27518 (rank : 349)	NC score	0.027903 (rank : 430)
Query Neighborhood Hits	436	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q03288, Q80ST0	Gene names	Asip, a
Domain Architecture
Description	Agouti signaling protein precursor (ASP) (Agouti switch protein) (Agouti coat color protein).

ATX3_MOUSE
θ value	5.27518 (rank : 350)	NC score	0.027356 (rank : 432)
Query Neighborhood Hits	436	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CVD2	Gene names	Atxn3, Mjd
Domain Architecture
Description	Ataxin-3 (EC 3.4.22.-) (Machado-Joseph disease protein 1 homolog).

BAZ2B_HUMAN
θ value	5.27518 (rank : 351)	NC score	0.034784 (rank : 409)
Query Neighborhood Hits	436	Target Neighborhood Hits	803	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

CENPF_HUMAN
θ value	5.27518 (rank : 352)	NC score	0.042293 (rank : 393)
Query Neighborhood Hits	436	Target Neighborhood Hits	1932	Shared Neighborhood Hits	143
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CENPT_MOUSE
θ value	5.27518 (rank : 353)	NC score	0.020237 (rank : 466)
Query Neighborhood Hits	436	Target Neighborhood Hits	115	Shared Neighborhood Hits	10
SwissProt Accessions	Q3TJM4, Q3TPY6, Q3UPD2, Q8BTH0, Q8BTP2, Q8R5E9	Gene names	Cenpt
Domain Architecture	No domain graphic available
Description	Centromere protein T (CENP-T).

COEA1_HUMAN
θ value	5.27518 (rank : 354)	NC score	0.004665 (rank : 527)
Query Neighborhood Hits	436	Target Neighborhood Hits	427	Shared Neighborhood Hits	10
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

EEA1_MOUSE
θ value	5.27518 (rank : 355)	NC score	0.028008 (rank : 429)
Query Neighborhood Hits	436	Target Neighborhood Hits	1637	Shared Neighborhood Hits	110
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

EF2K_HUMAN
θ value	5.27518 (rank : 356)	NC score	0.015712 (rank : 485)
Query Neighborhood Hits	436	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	O00418	Gene names	EEF2K
Domain Architecture
Description	Elongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase).

FGD1_HUMAN
θ value	5.27518 (rank : 357)	NC score	0.005540 (rank : 523)
Query Neighborhood Hits	436	Target Neighborhood Hits	367	Shared Neighborhood Hits	22
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

JPH4_MOUSE
θ value	5.27518 (rank : 358)	NC score	0.007341 (rank : 519)
Query Neighborhood Hits	436	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	Q80WT0, Q8BMI1	Gene names	Jph4, Jphl1
Domain Architecture	No domain graphic available
Description	Junctophilin-4 (Junctophilin-like 1 protein).

K0226_HUMAN
θ value	5.27518 (rank : 359)	NC score	0.013202 (rank : 497)
Query Neighborhood Hits	436	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	Q92622	Gene names	KIAA0226
Domain Architecture	No domain graphic available
Description	Protein KIAA0226.

K1210_HUMAN
θ value	5.27518 (rank : 360)	NC score	0.032744 (rank : 417)
Query Neighborhood Hits	436	Target Neighborhood Hits	219	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

MCR_MOUSE
θ value	5.27518 (rank : 361)	NC score	0.007449 (rank : 518)
Query Neighborhood Hits	436	Target Neighborhood Hits	162	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

MYH11_MOUSE
θ value	5.27518 (rank : 362)	NC score	0.025469 (rank : 438)
Query Neighborhood Hits	436	Target Neighborhood Hits	1777	Shared Neighborhood Hits	132
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

PEX2_MOUSE
θ value	5.27518 (rank : 363)	NC score	0.105031 (rank : 252)
Query Neighborhood Hits	436	Target Neighborhood Hits	57	Shared Neighborhood Hits	50
SwissProt Accessions	P55098, O35467	Gene names	Pxmp3, Paf1, Pex2, Pmp35
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3).

PHLPP_MOUSE
θ value	5.27518 (rank : 364)	NC score	0.001199 (rank : 541)
Query Neighborhood Hits	436	Target Neighborhood Hits	394	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

PP2CG_HUMAN
θ value	5.27518 (rank : 365)	NC score	0.015080 (rank : 489)
Query Neighborhood Hits	436	Target Neighborhood Hits	140	Shared Neighborhood Hits	13
SwissProt Accessions	O15355	Gene names	PPM1G, PPM1C
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C).

RN139_HUMAN
θ value	5.27518 (rank : 366)	NC score	0.059011 (rank : 340)
Query Neighborhood Hits	436	Target Neighborhood Hits	130	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WU17, O75485, Q7LDL3	Gene names	RNF139, TRC8
Domain Architecture	No domain graphic available
Description	RING finger protein 139 (Translocation in renal carcinoma on chromosome 8).

SRRM2_HUMAN
θ value	5.27518 (rank : 367)	NC score	0.058392 (rank : 343)
Query Neighborhood Hits	436	Target Neighborhood Hits	1296	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SUHW4_HUMAN
θ value	5.27518 (rank : 368)	NC score	0.005128 (rank : 524)
Query Neighborhood Hits	436	Target Neighborhood Hits	860	Shared Neighborhood Hits	47
SwissProt Accessions	Q6N043, Q6MZM6, Q6N085, Q9H0U5, Q9HCI8, Q9NXS0	Gene names	SUHW4, KIAA1584
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

TCP10_HUMAN
θ value	5.27518 (rank : 369)	NC score	0.025382 (rank : 439)
Query Neighborhood Hits	436	Target Neighborhood Hits	134	Shared Neighborhood Hits	18
SwissProt Accessions	Q12799	Gene names	TCP10, TCP10A
Domain Architecture
Description	T-complex protein 10A homolog.

TOIP2_HUMAN
θ value	5.27518 (rank : 370)	NC score	0.030287 (rank : 422)
Query Neighborhood Hits	436	Target Neighborhood Hits	102	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NFQ8	Gene names	TOR1AIP2, LULL1
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2 (Lumenal domain-like LAP1).

TRI42_HUMAN
θ value	5.27518 (rank : 371)	NC score	0.232312 (rank : 187)
Query Neighborhood Hits	436	Target Neighborhood Hits	283	Shared Neighborhood Hits	106
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI45_HUMAN
θ value	5.27518 (rank : 372)	NC score	0.192290 (rank : 209)
Query Neighborhood Hits	436	Target Neighborhood Hits	155	Shared Neighborhood Hits	93
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

UBP31_HUMAN
θ value	5.27518 (rank : 373)	NC score	0.015667 (rank : 486)
Query Neighborhood Hits	436	Target Neighborhood Hits	293	Shared Neighborhood Hits	30
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

AMFR2_HUMAN
θ value	6.88961 (rank : 374)	NC score	0.176325 (rank : 216)
Query Neighborhood Hits	436	Target Neighborhood Hits	219	Shared Neighborhood Hits	123
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

ANK1_MOUSE
θ value	6.88961 (rank : 375)	NC score	0.018398 (rank : 474)
Query Neighborhood Hits	436	Target Neighborhood Hits	430	Shared Neighborhood Hits	27
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

CD2L1_HUMAN
θ value	6.88961 (rank : 376)	NC score	0.004803 (rank : 526)
Query Neighborhood Hits	436	Target Neighborhood Hits	1467	Shared Neighborhood Hits	65
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CD2L2_HUMAN
θ value	6.88961 (rank : 377)	NC score	0.002516 (rank : 534)
Query Neighborhood Hits	436	Target Neighborhood Hits	1439	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

DPF3_MOUSE
θ value	6.88961 (rank : 378)	NC score	0.005051 (rank : 525)
Query Neighborhood Hits	436	Target Neighborhood Hits	327	Shared Neighborhood Hits	3
SwissProt Accessions	P58269	Gene names	Dpf3, Cerd4
Domain Architecture	No domain graphic available
Description	Zinc-finger protein Dpf3 (cer-d4).

E41L2_HUMAN
θ value	6.88961 (rank : 379)	NC score	0.009096 (rank : 511)
Query Neighborhood Hits	436	Target Neighborhood Hits	287	Shared Neighborhood Hits	27
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

G3BP_HUMAN
θ value	6.88961 (rank : 380)	NC score	0.010559 (rank : 506)
Query Neighborhood Hits	436	Target Neighborhood Hits	219	Shared Neighborhood Hits	13
SwissProt Accessions	Q13283	Gene names	G3BP, G3BP1
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 1 (EC 3.6.1.-) (ATP- dependent DNA helicase VIII) (GAP SH3-domain-binding protein 1) (G3BP- 1) (HDH-VIII).

GABP2_HUMAN
θ value	6.88961 (rank : 381)	NC score	0.018382 (rank : 475)
Query Neighborhood Hits	436	Target Neighborhood Hits	454	Shared Neighborhood Hits	19
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

GOGB1_HUMAN
θ value	6.88961 (rank : 382)	NC score	0.049539 (rank : 370)
Query Neighborhood Hits	436	Target Neighborhood Hits	2297	Shared Neighborhood Hits	179
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

GP73_HUMAN
θ value	6.88961 (rank : 383)	NC score	0.021657 (rank : 457)
Query Neighborhood Hits	436	Target Neighborhood Hits	309	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NBJ4, Q6IAF4, Q9NRB9	Gene names	GOLPH2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

H13_HUMAN
θ value	6.88961 (rank : 384)	NC score	0.010127 (rank : 509)
Query Neighborhood Hits	436	Target Neighborhood Hits	61	Shared Neighborhood Hits	7
SwissProt Accessions	P16402	Gene names	HIST1H1D, H1F3
Domain Architecture
Description	Histone H1.3 (Histone H1c).

IF39_HUMAN
θ value	6.88961 (rank : 385)	NC score	0.014874 (rank : 491)
Query Neighborhood Hits	436	Target Neighborhood Hits	187	Shared Neighborhood Hits	14
SwissProt Accessions	P55884, Q9UMF9	Gene names	EIF3S9
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) (Prt1 homolog) (hPrt1).

K0431_HUMAN
θ value	6.88961 (rank : 386)	NC score	0.016771 (rank : 480)
Query Neighborhood Hits	436	Target Neighborhood Hits	211	Shared Neighborhood Hits	7
SwissProt Accessions	O43313	Gene names	KIAA0431
Domain Architecture	No domain graphic available
Description	Protein KIAA0431.

KI21A_MOUSE
θ value	6.88961 (rank : 387)	NC score	0.013278 (rank : 495)
Query Neighborhood Hits	436	Target Neighborhood Hits	1317	Shared Neighborhood Hits	86
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

LIX1_HUMAN
θ value	6.88961 (rank : 388)	NC score	0.010084 (rank : 510)
Query Neighborhood Hits	436	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N485, Q8N7I2	Gene names	LIX1
Domain Architecture	No domain graphic available
Description	Protein limb expression 1 homolog.

MDFI_MOUSE
θ value	6.88961 (rank : 389)	NC score	0.016490 (rank : 481)
Query Neighborhood Hits	436	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	P70331, P70330, P70332, Q99JM9	Gene names	Mdfi
Domain Architecture	No domain graphic available
Description	MyoD family inhibitor (Myogenic repressor I-mf).

MYLIP_HUMAN
θ value	6.88961 (rank : 390)	NC score	0.054975 (rank : 355)
Query Neighborhood Hits	436	Target Neighborhood Hits	162	Shared Neighborhood Hits	79
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

NEUL1_HUMAN
θ value	6.88961 (rank : 391)	NC score	0.103397 (rank : 254)
Query Neighborhood Hits	436	Target Neighborhood Hits	114	Shared Neighborhood Hits	64
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

NEURL_MOUSE
θ value	6.88961 (rank : 392)	NC score	0.100890 (rank : 260)
Query Neighborhood Hits	436	Target Neighborhood Hits	106	Shared Neighborhood Hits	62
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

NFAT5_MOUSE
θ value	6.88961 (rank : 393)	NC score	0.012815 (rank : 498)
Query Neighborhood Hits	436	Target Neighborhood Hits	162	Shared Neighborhood Hits	11
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

PCGF4_HUMAN
θ value	6.88961 (rank : 394)	NC score	0.192650 (rank : 208)
Query Neighborhood Hits	436	Target Neighborhood Hits	161	Shared Neighborhood Hits	112
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
θ value	6.88961 (rank : 395)	NC score	0.191548 (rank : 210)
Query Neighborhood Hits	436	Target Neighborhood Hits	163	Shared Neighborhood Hits	111
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

PTN21_MOUSE
θ value	6.88961 (rank : 396)	NC score	0.002414 (rank : 535)
Query Neighborhood Hits	436	Target Neighborhood Hits	155	Shared Neighborhood Hits	10
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

RFC1_MOUSE
θ value	6.88961 (rank : 397)	NC score	0.056731 (rank : 349)
Query Neighborhood Hits	436	Target Neighborhood Hits	290	Shared Neighborhood Hits	40
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

RNF24_HUMAN
θ value	6.88961 (rank : 398)	NC score	0.065823 (rank : 325)
Query Neighborhood Hits	436	Target Neighborhood Hits	122	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y225, Q9UMH1	Gene names	RNF24
Domain Architecture
Description	RING finger protein 24.

RUFY2_MOUSE
θ value	6.88961 (rank : 399)	NC score	0.019232 (rank : 467)
Query Neighborhood Hits	436	Target Neighborhood Hits	820	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

SPRL1_MOUSE
θ value	6.88961 (rank : 400)	NC score	0.036223 (rank : 403)
Query Neighborhood Hits	436	Target Neighborhood Hits	403	Shared Neighborhood Hits	56
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

TBX18_HUMAN
θ value	6.88961 (rank : 401)	NC score	0.002125 (rank : 540)
Query Neighborhood Hits	436	Target Neighborhood Hits	148	Shared Neighborhood Hits	4
SwissProt Accessions	O95935, Q7Z6U4, Q9UJI6	Gene names	TBX18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

TM131_MOUSE
θ value	6.88961 (rank : 402)	NC score	0.023798 (rank : 445)
Query Neighborhood Hits	436	Target Neighborhood Hits	156	Shared Neighborhood Hits	18
SwissProt Accessions	O70472	Gene names	Tmem131, D1Bwg0491e, Rw1
Domain Architecture	No domain graphic available
Description	Transmembrane protein 131 (Protein RW1).

TS1R1_MOUSE
θ value	6.88961 (rank : 403)	NC score	0.002738 (rank : 533)
Query Neighborhood Hits	436	Target Neighborhood Hits	57	Shared Neighborhood Hits	2
SwissProt Accessions	Q99PG6, Q6NS58, Q923J9, Q925I5, Q99PG5	Gene names	Tas1r1, Gpr70, T1r1, Tr1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70).

UCHL1_MOUSE
θ value	6.88961 (rank : 404)	NC score	0.008722 (rank : 513)
Query Neighborhood Hits	436	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0P9, Q9R122	Gene names	Uchl1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase isozyme L1 (EC 3.4.19.12) (EC 6.-.-.-) (UCH-L1) (Ubiquitin thioesterase L1) (Neuron cytoplasmic protein 9.5) (PGP 9.5) (PGP9.5).

ABTAP_MOUSE
θ value	8.99809 (rank : 405)	NC score	0.030424 (rank : 421)
Query Neighborhood Hits	436	Target Neighborhood Hits	381	Shared Neighborhood Hits	37
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

ACINU_MOUSE
θ value	8.99809 (rank : 406)	NC score	0.048208 (rank : 374)
Query Neighborhood Hits	436	Target Neighborhood Hits	712	Shared Neighborhood Hits	59
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

AF9_HUMAN
θ value	8.99809 (rank : 407)	NC score	0.031598 (rank : 420)
Query Neighborhood Hits	436	Target Neighborhood Hits	202	Shared Neighborhood Hits	20
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

AFF4_HUMAN
θ value	8.99809 (rank : 408)	NC score	0.048224 (rank : 373)
Query Neighborhood Hits	436	Target Neighborhood Hits	611	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

CD97_HUMAN
θ value	8.99809 (rank : 409)	NC score	-0.003803 (rank : 549)
Query Neighborhood Hits	436	Target Neighborhood Hits	353	Shared Neighborhood Hits	4
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CDA7L_HUMAN
θ value	8.99809 (rank : 410)	NC score	0.016017 (rank : 483)
Query Neighborhood Hits	436	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	Q96GN5, Q6PIL4, Q86YT0, Q8IXN5, Q96C70, Q9H9A2, Q9NPV2	Gene names	CDCA7L, HR1, JPO2, R1
Domain Architecture	No domain graphic available
Description	Cell division cycle-associated 7-like protein (Protein JPO2) (Transcription factor RAM2).

CE290_HUMAN
θ value	8.99809 (rank : 411)	NC score	0.034993 (rank : 407)
Query Neighborhood Hits	436	Target Neighborhood Hits	1553	Shared Neighborhood Hits	124
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CENPE_HUMAN
θ value	8.99809 (rank : 412)	NC score	0.034821 (rank : 408)
Query Neighborhood Hits	436	Target Neighborhood Hits	2060	Shared Neighborhood Hits	150
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CJ078_HUMAN
θ value	8.99809 (rank : 413)	NC score	0.012491 (rank : 501)
Query Neighborhood Hits	436	Target Neighborhood Hits	61	Shared Neighborhood Hits	8
SwissProt Accessions	Q86XK3, Q5JT40, Q8WW47	Gene names	C10orf78
Domain Architecture	No domain graphic available
Description	Protein C10orf78.

DMRTC_MOUSE
θ value	8.99809 (rank : 414)	NC score	0.012508 (rank : 500)
Query Neighborhood Hits	436	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D9R7, Q2PMY0, Q9D5U3	Gene names	Dmrtc1, Dmrt8.1
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C1 (Doublesex- and mab-3-related transcription factor 8.1).

FOXN3_HUMAN
θ value	8.99809 (rank : 415)	NC score	0.000885 (rank : 542)
Query Neighborhood Hits	436	Target Neighborhood Hits	121	Shared Neighborhood Hits	6
SwissProt Accessions	O00409, Q96II7, Q9UIE7	Gene names	CHES1, FOXN3
Domain Architecture
Description	Checkpoint suppressor 1 (Forkhead box protein N3).

G3BP_MOUSE
θ value	8.99809 (rank : 416)	NC score	0.007598 (rank : 517)
Query Neighborhood Hits	436	Target Neighborhood Hits	209	Shared Neighborhood Hits	7
SwissProt Accessions	P97855	Gene names	G3bp, G3bp1
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 1 (EC 3.6.1.-) (ATP- dependent DNA helicase VIII) (GAP SH3-domain-binding protein 1) (G3BP- 1) (HDH-VIII).

HOMEZ_HUMAN
θ value	8.99809 (rank : 417)	NC score	0.010319 (rank : 508)
Query Neighborhood Hits	436	Target Neighborhood Hits	110	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IX15, Q6P049, Q86XB6, Q9P2A5	Gene names	HOMEZ, KIAA1443
Domain Architecture
Description	Homeobox and leucine zipper protein Homez (Homeodomain leucine zipper- containing factor).

HORN_MOUSE
θ value	8.99809 (rank : 418)	NC score	0.015508 (rank : 487)
Query Neighborhood Hits	436	Target Neighborhood Hits	218	Shared Neighborhood Hits	16
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

ICAL_MOUSE
θ value	8.99809 (rank : 419)	NC score	0.026659 (rank : 435)
Query Neighborhood Hits	436	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	P51125, Q9EQV4, Q9EQV5, Q9QXQ3, Q9QXQ4, Q9R0N1	Gene names	Cast
Domain Architecture
Description	Calpastatin (Calpain inhibitor).

IYD1_HUMAN
θ value	8.99809 (rank : 420)	NC score	0.011104 (rank : 503)
Query Neighborhood Hits	436	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PHW0, Q2VPW0, Q2VPW1, Q5F1L5, Q5F1L6, Q5THM4, Q6ZP69, Q7Z7D7, Q7Z7D8	Gene names	IYD, C6orf71, DEHAL1
Domain Architecture	No domain graphic available
Description	Iodotyrosine dehalogenase 1 precursor (EC 1.-.-.-) (IYD-1).

MAP1B_MOUSE
θ value	8.99809 (rank : 421)	NC score	0.063598 (rank : 328)
Query Neighborhood Hits	436	Target Neighborhood Hits	977	Shared Neighborhood Hits	86
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MAST2_MOUSE
θ value	8.99809 (rank : 422)	NC score	-0.003463 (rank : 547)
Query Neighborhood Hits	436	Target Neighborhood Hits	1110	Shared Neighborhood Hits	33
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MMTA2_MOUSE
θ value	8.99809 (rank : 423)	NC score	0.020681 (rank : 462)
Query Neighborhood Hits	436	Target Neighborhood Hits	40	Shared Neighborhood Hits	8
SwissProt Accessions	Q99LX5, Q9CSK6	Gene names	Mmtag2
Domain Architecture	No domain graphic available
Description	Multiple myeloma tumor-associated protein 2 homolog.

NOP56_HUMAN
θ value	8.99809 (rank : 424)	NC score	0.019196 (rank : 468)
Query Neighborhood Hits	436	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	O00567, Q9NQ05	Gene names	NOL5A, NOP56
Domain Architecture
Description	Nucleolar protein Nop56 (Nucleolar protein 5A).

OPTN_MOUSE
θ value	8.99809 (rank : 425)	NC score	0.032897 (rank : 415)
Query Neighborhood Hits	436	Target Neighborhood Hits	1120	Shared Neighborhood Hits	78
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

PCLO_HUMAN
θ value	8.99809 (rank : 426)	NC score	0.038932 (rank : 400)
Query Neighborhood Hits	436	Target Neighborhood Hits	2046	Shared Neighborhood Hits	122
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PTN23_MOUSE
θ value	8.99809 (rank : 427)	NC score	0.006931 (rank : 520)
Query Neighborhood Hits	436	Target Neighborhood Hits	726	Shared Neighborhood Hits	43
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

RBM19_MOUSE
θ value	8.99809 (rank : 428)	NC score	0.002157 (rank : 538)
Query Neighborhood Hits	436	Target Neighborhood Hits	296	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R3C6, Q8BHR0, Q9CW63	Gene names	Rbm19
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

RERE_MOUSE
θ value	8.99809 (rank : 429)	NC score	0.022195 (rank : 454)
Query Neighborhood Hits	436	Target Neighborhood Hits	785	Shared Neighborhood Hits	44
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RHG07_HUMAN
θ value	8.99809 (rank : 430)	NC score	0.002255 (rank : 537)
Query Neighborhood Hits	436	Target Neighborhood Hits	108	Shared Neighborhood Hits	6
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RNF24_MOUSE
θ value	8.99809 (rank : 431)	NC score	0.062989 (rank : 330)
Query Neighborhood Hits	436	Target Neighborhood Hits	124	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BGI1	Gene names	Rnf24
Domain Architecture	No domain graphic available
Description	RING finger protein 24.

RNF26_HUMAN
θ value	8.99809 (rank : 432)	NC score	0.102685 (rank : 257)
Query Neighborhood Hits	436	Target Neighborhood Hits	95	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

SLK_HUMAN
θ value	8.99809 (rank : 433)	NC score	0.006354 (rank : 522)
Query Neighborhood Hits	436	Target Neighborhood Hits	1775	Shared Neighborhood Hits	97
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

TARA_MOUSE
θ value	8.99809 (rank : 434)	NC score	0.039601 (rank : 398)
Query Neighborhood Hits	436	Target Neighborhood Hits	1133	Shared Neighborhood Hits	80
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

UB7I3_HUMAN
θ value	8.99809 (rank : 435)	NC score	0.099191 (rank : 262)
Query Neighborhood Hits	436	Target Neighborhood Hits	136	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

UB7I3_MOUSE
θ value	8.99809 (rank : 436)	NC score	0.111868 (rank : 242)
Query Neighborhood Hits	436	Target Neighborhood Hits	131	Shared Neighborhood Hits	74
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

AMFR_MOUSE
θ value	θ > 10 (rank : 437)	NC score	0.161412 (rank : 223)
Query Neighborhood Hits	436	Target Neighborhood Hits	208	Shared Neighborhood Hits	116
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

ARD1_HUMAN
θ value	θ > 10 (rank : 438)	NC score	0.091921 (rank : 272)
Query Neighborhood Hits	436	Target Neighborhood Hits	621	Shared Neighborhood Hits	76
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

ARD1_MOUSE
θ value	θ > 10 (rank : 439)	NC score	0.095995 (rank : 266)
Query Neighborhood Hits	436	Target Neighborhood Hits	573	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

ATRX_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.056746 (rank : 348)
Query Neighborhood Hits	436	Target Neighborhood Hits	842	Shared Neighborhood Hits	91
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

BIRC2_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.076307 (rank : 297)
Query Neighborhood Hits	436	Target Neighborhood Hits	142	Shared Neighborhood Hits	88
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

BIRC2_MOUSE
θ value	θ > 10 (rank : 442)	NC score	0.072611 (rank : 309)
Query Neighborhood Hits	436	Target Neighborhood Hits	137	Shared Neighborhood Hits	81
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

BIRC3_HUMAN
θ value	θ > 10 (rank : 443)	NC score	0.077249 (rank : 294)
Query Neighborhood Hits	436	Target Neighborhood Hits	133	Shared Neighborhood Hits	81
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

BIRC3_MOUSE
θ value	θ > 10 (rank : 444)	NC score	0.066681 (rank : 323)
Query Neighborhood Hits	436	Target Neighborhood Hits	113	Shared Neighborhood Hits	71
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

BIRC8_HUMAN
θ value	θ > 10 (rank : 445)	NC score	0.093228 (rank : 270)
Query Neighborhood Hits	436	Target Neighborhood Hits	121	Shared Neighborhood Hits	79
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

BRAP_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.081885 (rank : 284)
Query Neighborhood Hits	436	Target Neighborhood Hits	560	Shared Neighborhood Hits	88
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.080307 (rank : 287)
Query Neighborhood Hits	436	Target Neighborhood Hits	409	Shared Neighborhood Hits	76
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

BSPRY_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.285609 (rank : 150)
Query Neighborhood Hits	436	Target Neighborhood Hits	115	Shared Neighborhood Hits	68
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BSPRY_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.292010 (rank : 146)
Query Neighborhood Hits	436	Target Neighborhood Hits	163	Shared Neighborhood Hits	75
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BT1A1_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.269954 (rank : 161)
Query Neighborhood Hits	436	Target Neighborhood Hits	322	Shared Neighborhood Hits	61
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT1A1_MOUSE
θ value	θ > 10 (rank : 451)	NC score	0.274132 (rank : 153)
Query Neighborhood Hits	436	Target Neighborhood Hits	252	Shared Neighborhood Hits	61
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT2A1_HUMAN
θ value	θ > 10 (rank : 452)	NC score	0.261295 (rank : 169)
Query Neighborhood Hits	436	Target Neighborhood Hits	185	Shared Neighborhood Hits	59
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

BT2A2_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.270314 (rank : 158)
Query Neighborhood Hits	436	Target Neighborhood Hits	191	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

BT2A3_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.260904 (rank : 171)
Query Neighborhood Hits	436	Target Neighborhood Hits	195	Shared Neighborhood Hits	56
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

BT3A1_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.269998 (rank : 160)
Query Neighborhood Hits	436	Target Neighborhood Hits	229	Shared Neighborhood Hits	61
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

BT3A3_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.271974 (rank : 156)
Query Neighborhood Hits	436	Target Neighborhood Hits	233	Shared Neighborhood Hits	61
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

BTNL3_HUMAN
θ value	θ > 10 (rank : 457)	NC score	0.267641 (rank : 163)
Query Neighborhood Hits	436	Target Neighborhood Hits	143	Shared Neighborhood Hits	57
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

BTNL8_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.258411 (rank : 173)
Query Neighborhood Hits	436	Target Neighborhood Hits	177	Shared Neighborhood Hits	59
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

BTNL9_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.267545 (rank : 164)
Query Neighborhood Hits	436	Target Neighborhood Hits	125	Shared Neighborhood Hits	56
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

CNOT4_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.079085 (rank : 289)
Query Neighborhood Hits	436	Target Neighborhood Hits	207	Shared Neighborhood Hits	46
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CNOT4_MOUSE
θ value	θ > 10 (rank : 461)	NC score	0.077556 (rank : 293)
Query Neighborhood Hits	436	Target Neighborhood Hits	277	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

DZIP3_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.056083 (rank : 352)
Query Neighborhood Hits	436	Target Neighborhood Hits	414	Shared Neighborhood Hits	71
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

ERMAP_HUMAN
θ value	θ > 10 (rank : 463)	NC score	0.309481 (rank : 136)
Query Neighborhood Hits	436	Target Neighborhood Hits	155	Shared Neighborhood Hits	60
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

ERMAP_MOUSE
θ value	θ > 10 (rank : 464)	NC score	0.285642 (rank : 149)
Query Neighborhood Hits	436	Target Neighborhood Hits	231	Shared Neighborhood Hits	57
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

FSD1L_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.073012 (rank : 308)
Query Neighborhood Hits	436	Target Neighborhood Hits	57	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BXM9, Q5T880	Gene names	FSD1L, CCDC10, CSDUFD1, FSD1NL
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

FSD1L_MOUSE
θ value	θ > 10 (rank : 466)	NC score	0.082428 (rank : 281)
Query Neighborhood Hits	436	Target Neighborhood Hits	78	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BYN5, Q3USW7	Gene names	Fsd1l, Ccdc10, Csdufd1, Fsd1nl
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

LEO1_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.066541 (rank : 324)
Query Neighborhood Hits	436	Target Neighborhood Hits	958	Shared Neighborhood Hits	98
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LEO1_MOUSE
θ value	θ > 10 (rank : 468)	NC score	0.071435 (rank : 312)
Query Neighborhood Hits	436	Target Neighborhood Hits	946	Shared Neighborhood Hits	104
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

MAT1_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.079090 (rank : 288)
Query Neighborhood Hits	436	Target Neighborhood Hits	179	Shared Neighborhood Hits	46
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

MAT1_MOUSE
θ value	θ > 10 (rank : 470)	NC score	0.081974 (rank : 283)
Query Neighborhood Hits	436	Target Neighborhood Hits	217	Shared Neighborhood Hits	46
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

MEFV_HUMAN
θ value	θ > 10 (rank : 471)	NC score	0.364140 (rank : 114)
Query Neighborhood Hits	436	Target Neighborhood Hits	431	Shared Neighborhood Hits	111
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

MEFV_MOUSE
θ value	θ > 10 (rank : 472)	NC score	0.333668 (rank : 124)
Query Neighborhood Hits	436	Target Neighborhood Hits	236	Shared Neighborhood Hits	108
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

MGRN1_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.102583 (rank : 259)
Query Neighborhood Hits	436	Target Neighborhood Hits	192	Shared Neighborhood Hits	95
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

MGRN1_MOUSE
θ value	θ > 10 (rank : 474)	NC score	0.102659 (rank : 258)
Query Neighborhood Hits	436	Target Neighborhood Hits	149	Shared Neighborhood Hits	87
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

MKRN2_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.073298 (rank : 306)
Query Neighborhood Hits	436	Target Neighborhood Hits	129	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H000, Q8N391, Q96BD4, Q9BUY2, Q9NRY1	Gene names	MKRN2, RNF62
Domain Architecture
Description	Makorin-2 (RING finger protein 62).

MKRN2_MOUSE
θ value	θ > 10 (rank : 476)	NC score	0.075435 (rank : 299)
Query Neighborhood Hits	436	Target Neighborhood Hits	130	Shared Neighborhood Hits	67
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

MKRN3_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.067293 (rank : 322)
Query Neighborhood Hits	436	Target Neighborhood Hits	165	Shared Neighborhood Hits	69
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

MKRN3_MOUSE
θ value	θ > 10 (rank : 478)	NC score	0.051936 (rank : 364)
Query Neighborhood Hits	436	Target Neighborhood Hits	137	Shared Neighborhood Hits	55
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

PCGF6_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.222115 (rank : 195)
Query Neighborhood Hits	436	Target Neighborhood Hits	178	Shared Neighborhood Hits	123
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF6_MOUSE
θ value	θ > 10 (rank : 480)	NC score	0.226638 (rank : 194)
Query Neighborhood Hits	436	Target Neighborhood Hits	163	Shared Neighborhood Hits	121
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PDZK4_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.056886 (rank : 347)
Query Neighborhood Hits	436	Target Neighborhood Hits	165	Shared Neighborhood Hits	12
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PDZK4_MOUSE
θ value	θ > 10 (rank : 482)	NC score	0.059143 (rank : 339)
Query Neighborhood Hits	436	Target Neighborhood Hits	165	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PJA1_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.082421 (rank : 282)
Query Neighborhood Hits	436	Target Neighborhood Hits	159	Shared Neighborhood Hits	66
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

PJA1_MOUSE
θ value	θ > 10 (rank : 484)	NC score	0.074097 (rank : 303)
Query Neighborhood Hits	436	Target Neighborhood Hits	145	Shared Neighborhood Hits	63
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

PML_HUMAN
θ value	θ > 10 (rank : 485)	NC score	0.196854 (rank : 206)
Query Neighborhood Hits	436	Target Neighborhood Hits	248	Shared Neighborhood Hits	113
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

RBBP6_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.181168 (rank : 214)
Query Neighborhood Hits	436	Target Neighborhood Hits	1135	Shared Neighborhood Hits	210
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	θ > 10 (rank : 487)	NC score	0.196329 (rank : 207)
Query Neighborhood Hits	436	Target Neighborhood Hits	1014	Shared Neighborhood Hits	210
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RFFL_MOUSE
θ value	θ > 10 (rank : 488)	NC score	0.075092 (rank : 301)
Query Neighborhood Hits	436	Target Neighborhood Hits	145	Shared Neighborhood Hits	69
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

RKHD1_HUMAN
θ value	θ > 10 (rank : 489)	NC score	0.107826 (rank : 249)
Query Neighborhood Hits	436	Target Neighborhood Hits	163	Shared Neighborhood Hits	70
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

RN103_HUMAN
θ value	θ > 10 (rank : 490)	NC score	0.073393 (rank : 305)
Query Neighborhood Hits	436	Target Neighborhood Hits	153	Shared Neighborhood Hits	69
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

RN103_MOUSE
θ value	θ > 10 (rank : 491)	NC score	0.073254 (rank : 307)
Query Neighborhood Hits	436	Target Neighborhood Hits	143	Shared Neighborhood Hits	66
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

RN122_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.062681 (rank : 331)
Query Neighborhood Hits	436	Target Neighborhood Hits	121	Shared Neighborhood Hits	61
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN122_MOUSE
θ value	θ > 10 (rank : 493)	NC score	0.059451 (rank : 337)
Query Neighborhood Hits	436	Target Neighborhood Hits	121	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN123_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.089566 (rank : 275)
Query Neighborhood Hits	436	Target Neighborhood Hits	175	Shared Neighborhood Hits	109
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN123_MOUSE
θ value	θ > 10 (rank : 495)	NC score	0.089812 (rank : 274)
Query Neighborhood Hits	436	Target Neighborhood Hits	174	Shared Neighborhood Hits	111
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN126_HUMAN
θ value	θ > 10 (rank : 496)	NC score	0.078758 (rank : 290)
Query Neighborhood Hits	436	Target Neighborhood Hits	126	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN126_MOUSE
θ value	θ > 10 (rank : 497)	NC score	0.085797 (rank : 278)
Query Neighborhood Hits	436	Target Neighborhood Hits	143	Shared Neighborhood Hits	76
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN139_MOUSE
θ value	θ > 10 (rank : 498)	NC score	0.056658 (rank : 350)
Query Neighborhood Hits	436	Target Neighborhood Hits	131	Shared Neighborhood Hits	58
SwissProt Accessions	Q7TMV1, Q8BZU9	Gene names	Rnf139
Domain Architecture	No domain graphic available
Description	RING finger protein 139.

RN141_HUMAN
θ value	θ > 10 (rank : 499)	NC score	0.244568 (rank : 179)
Query Neighborhood Hits	436	Target Neighborhood Hits	199	Shared Neighborhood Hits	139
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
θ value	θ > 10 (rank : 500)	NC score	0.243842 (rank : 181)
Query Neighborhood Hits	436	Target Neighborhood Hits	200	Shared Neighborhood Hits	139
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN152_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.132178 (rank : 231)
Query Neighborhood Hits	436	Target Neighborhood Hits	107	Shared Neighborhood Hits	69
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

RN152_MOUSE
θ value	θ > 10 (rank : 502)	NC score	0.141653 (rank : 229)
Query Neighborhood Hits	436	Target Neighborhood Hits	109	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

RN165_HUMAN
θ value	θ > 10 (rank : 503)	NC score	0.078272 (rank : 291)
Query Neighborhood Hits	436	Target Neighborhood Hits	151	Shared Neighborhood Hits	65
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

RN167_HUMAN
θ value	θ > 10 (rank : 504)	NC score	0.056459 (rank : 351)
Query Neighborhood Hits	436	Target Neighborhood Hits	157	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN167_MOUSE
θ value	θ > 10 (rank : 505)	NC score	0.061148 (rank : 334)
Query Neighborhood Hits	436	Target Neighborhood Hits	157	Shared Neighborhood Hits	70
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN169_HUMAN
θ value	θ > 10 (rank : 506)	NC score	0.260393 (rank : 172)
Query Neighborhood Hits	436	Target Neighborhood Hits	203	Shared Neighborhood Hits	117
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

RN183_HUMAN
θ value	θ > 10 (rank : 507)	NC score	0.261303 (rank : 168)
Query Neighborhood Hits	436	Target Neighborhood Hits	126	Shared Neighborhood Hits	102
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RN183_MOUSE
θ value	θ > 10 (rank : 508)	NC score	0.229358 (rank : 189)
Query Neighborhood Hits	436	Target Neighborhood Hits	119	Shared Neighborhood Hits	97
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RNF13_HUMAN
θ value	θ > 10 (rank : 509)	NC score	0.050881 (rank : 368)
Query Neighborhood Hits	436	Target Neighborhood Hits	147	Shared Neighborhood Hits	57
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

RNF13_MOUSE
θ value	θ > 10 (rank : 510)	NC score	0.051717 (rank : 365)
Query Neighborhood Hits	436	Target Neighborhood Hits	164	Shared Neighborhood Hits	65
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

RNF32_HUMAN
θ value	θ > 10 (rank : 511)	NC score	0.106410 (rank : 251)
Query Neighborhood Hits	436	Target Neighborhood Hits	133	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

RNF32_MOUSE
θ value	θ > 10 (rank : 512)	NC score	0.095073 (rank : 268)
Query Neighborhood Hits	436	Target Neighborhood Hits	129	Shared Neighborhood Hits	61
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

RNF34_HUMAN
θ value	θ > 10 (rank : 513)	NC score	0.107222 (rank : 250)
Query Neighborhood Hits	436	Target Neighborhood Hits	153	Shared Neighborhood Hits	84
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RNF34_MOUSE
θ value	θ > 10 (rank : 514)	NC score	0.110003 (rank : 244)
Query Neighborhood Hits	436	Target Neighborhood Hits	160	Shared Neighborhood Hits	86
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

RNF37_MOUSE
θ value	θ > 10 (rank : 515)	NC score	0.062032 (rank : 333)
Query Neighborhood Hits	436	Target Neighborhood Hits	102	Shared Neighborhood Hits	55
SwissProt Accessions	Q925F4	Gene names	Ubox5, Rnf37, Ubce7ip5, Uip5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (UbcM4-interacting protein 5) (U-box domain-containing protein 5).

SFRIP_HUMAN
θ value	θ > 10 (rank : 516)	NC score	0.051325 (rank : 367)
Query Neighborhood Hits	436	Target Neighborhood Hits	530	Shared Neighborhood Hits	64
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

SPRY4_HUMAN
θ value	θ > 10 (rank : 517)	NC score	0.244026 (rank : 180)
Query Neighborhood Hits	436	Target Neighborhood Hits	79	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

SPRY4_MOUSE
θ value	θ > 10 (rank : 518)	NC score	0.251581 (rank : 176)
Query Neighborhood Hits	436	Target Neighborhood Hits	82	Shared Neighborhood Hits	58
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TGON2_HUMAN
θ value	θ > 10 (rank : 519)	NC score	0.069377 (rank : 318)
Query Neighborhood Hits	436	Target Neighborhood Hits	1037	Shared Neighborhood Hits	100
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TIF1A_HUMAN
θ value	θ > 10 (rank : 520)	NC score	0.110463 (rank : 243)
Query Neighborhood Hits	436	Target Neighborhood Hits	327	Shared Neighborhood Hits	96
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TIF1A_MOUSE
θ value	θ > 10 (rank : 521)	NC score	0.097731 (rank : 264)
Query Neighborhood Hits	436	Target Neighborhood Hits	307	Shared Neighborhood Hits	88
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TIF1B_HUMAN
θ value	θ > 10 (rank : 522)	NC score	0.143012 (rank : 228)
Query Neighborhood Hits	436	Target Neighborhood Hits	312	Shared Neighborhood Hits	98
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
θ value	θ > 10 (rank : 523)	NC score	0.140264 (rank : 230)
Query Neighborhood Hits	436	Target Neighborhood Hits	276	Shared Neighborhood Hits	93
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TIF1G_HUMAN
θ value	θ > 10 (rank : 524)	NC score	0.169859 (rank : 221)
Query Neighborhood Hits	436	Target Neighborhood Hits	410	Shared Neighborhood Hits	115
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
θ value	θ > 10 (rank : 525)	NC score	0.167553 (rank : 222)
Query Neighborhood Hits	436	Target Neighborhood Hits	498	Shared Neighborhood Hits	119
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TRAF1_HUMAN
θ value	θ > 10 (rank : 526)	NC score	0.070982 (rank : 313)
Query Neighborhood Hits	436	Target Neighborhood Hits	65	Shared Neighborhood Hits	16
SwissProt Accessions	Q13077, Q8NF13	Gene names	TRAF1, EBI6
Domain Architecture
Description	TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6).

TRAF1_MOUSE
θ value	θ > 10 (rank : 527)	NC score	0.070454 (rank : 316)
Query Neighborhood Hits	436	Target Neighborhood Hits	52	Shared Neighborhood Hits	12
SwissProt Accessions	P39428	Gene names	Traf1
Domain Architecture
Description	TNF receptor-associated factor 1.

TRAF4_MOUSE
θ value	θ > 10 (rank : 528)	NC score	0.178456 (rank : 215)
Query Neighborhood Hits	436	Target Neighborhood Hits	338	Shared Neighborhood Hits	112
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

TRAIP_HUMAN
θ value	θ > 10 (rank : 529)	NC score	0.108319 (rank : 247)
Query Neighborhood Hits	436	Target Neighborhood Hits	780	Shared Neighborhood Hits	117
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
θ value	θ > 10 (rank : 530)	NC score	0.096729 (rank : 265)
Query Neighborhood Hits	436	Target Neighborhood Hits	745	Shared Neighborhood Hits	109
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

TRI14_HUMAN
θ value	θ > 10 (rank : 531)	NC score	0.325135 (rank : 131)
Query Neighborhood Hits	436	Target Neighborhood Hits	143	Shared Neighborhood Hits	81
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

TRI14_MOUSE
θ value	θ > 10 (rank : 532)	NC score	0.322840 (rank : 133)
Query Neighborhood Hits	436	Target Neighborhood Hits	137	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRI16_HUMAN
θ value	θ > 10 (rank : 533)	NC score	0.287565 (rank : 147)
Query Neighborhood Hits	436	Target Neighborhood Hits	231	Shared Neighborhood Hits	86
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI16_MOUSE
θ value	θ > 10 (rank : 534)	NC score	0.294949 (rank : 145)
Query Neighborhood Hits	436	Target Neighborhood Hits	196	Shared Neighborhood Hits	78
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI29_HUMAN
θ value	θ > 10 (rank : 535)	NC score	0.272960 (rank : 154)
Query Neighborhood Hits	436	Target Neighborhood Hits	273	Shared Neighborhood Hits	83
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRI29_MOUSE
θ value	θ > 10 (rank : 536)	NC score	0.276957 (rank : 152)
Query Neighborhood Hits	436	Target Neighborhood Hits	306	Shared Neighborhood Hits	86
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

TRI37_HUMAN
θ value	θ > 10 (rank : 537)	NC score	0.332836 (rank : 125)
Query Neighborhood Hits	436	Target Neighborhood Hits	307	Shared Neighborhood Hits	149
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
θ value	θ > 10 (rank : 538)	NC score	0.332692 (rank : 126)
Query Neighborhood Hits	436	Target Neighborhood Hits	316	Shared Neighborhood Hits	149
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI42_MOUSE
θ value	θ > 10 (rank : 539)	NC score	0.227365 (rank : 192)
Query Neighborhood Hits	436	Target Neighborhood Hits	316	Shared Neighborhood Hits	114
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI44_HUMAN
θ value	θ > 10 (rank : 540)	NC score	0.298222 (rank : 143)
Query Neighborhood Hits	436	Target Neighborhood Hits	393	Shared Neighborhood Hits	101
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TRI44_MOUSE
θ value	θ > 10 (rank : 541)	NC score	0.304107 (rank : 139)
Query Neighborhood Hits	436	Target Neighborhood Hits	327	Shared Neighborhood Hits	94
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TRI66_HUMAN
θ value	θ > 10 (rank : 542)	NC score	0.057979 (rank : 344)
Query Neighborhood Hits	436	Target Neighborhood Hits	479	Shared Neighborhood Hits	71
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_MOUSE
θ value	θ > 10 (rank : 543)	NC score	0.058611 (rank : 341)
Query Neighborhood Hits	436	Target Neighborhood Hits	491	Shared Neighborhood Hits	71
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TTF2_MOUSE
θ value	θ > 10 (rank : 544)	NC score	0.051650 (rank : 366)
Query Neighborhood Hits	436	Target Neighborhood Hits	364	Shared Neighborhood Hits	52
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

TXND2_MOUSE
θ value	θ > 10 (rank : 545)	NC score	0.075422 (rank : 300)
Query Neighborhood Hits	436	Target Neighborhood Hits	828	Shared Neighborhood Hits	109
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

ZN364_HUMAN
θ value	θ > 10 (rank : 546)	NC score	0.087924 (rank : 276)
Query Neighborhood Hits	436	Target Neighborhood Hits	140	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

ZN364_MOUSE
θ value	θ > 10 (rank : 547)	NC score	0.082485 (rank : 280)
Query Neighborhood Hits	436	Target Neighborhood Hits	140	Shared Neighborhood Hits	69
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

ZSWM2_HUMAN
θ value	θ > 10 (rank : 548)	NC score	0.064102 (rank : 327)
Query Neighborhood Hits	436	Target Neighborhood Hits	151	Shared Neighborhood Hits	45
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

ZSWM2_MOUSE
θ value	θ > 10 (rank : 549)	NC score	0.052107 (rank : 362)
Query Neighborhood Hits	436	Target Neighborhood Hits	132	Shared Neighborhood Hits	47
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

Hits sorted by NC score

BRCA1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	436	Target Neighborhood Hits	436	Shared Neighborhood Hits	436
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

BRCA1_HUMAN
NC score	0.931605 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	436	Target Neighborhood Hits	381	Shared Neighborhood Hits	229
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

TRI31_HUMAN
NC score	0.604627 (rank : 3)	θ value	1.80886e-08 (rank : 7)
Query Neighborhood Hits	436	Target Neighborhood Hits	299	Shared Neighborhood Hits	194
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI40_HUMAN
NC score	0.577524 (rank : 4)	θ value	4.1701e-05 (rank : 52)
Query Neighborhood Hits	436	Target Neighborhood Hits	279	Shared Neighborhood Hits	182
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI26_MOUSE
NC score	0.567681 (rank : 5)	θ value	1.99992e-07 (rank : 15)
Query Neighborhood Hits	436	Target Neighborhood Hits	339	Shared Neighborhood Hits	200
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI26_HUMAN
NC score	0.567473 (rank : 6)	θ value	2.61198e-07 (rank : 16)
Query Neighborhood Hits	436	Target Neighborhood Hits	335	Shared Neighborhood Hits	200
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI12_MOUSE
NC score	0.566775 (rank : 7)	θ value	4.1701e-05 (rank : 49)
Query Neighborhood Hits	436	Target Neighborhood Hits	387	Shared Neighborhood Hits	191
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI30_MOUSE
NC score	0.561019 (rank : 8)	θ value	6.87365e-08 (rank : 11)
Query Neighborhood Hits	436	Target Neighborhood Hits	434	Shared Neighborhood Hits	205
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRI73_HUMAN
NC score	0.560356 (rank : 9)	θ value	1.87187e-05 (rank : 41)
Query Neighborhood Hits	436	Target Neighborhood Hits	258	Shared Neighborhood Hits	184
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI74_HUMAN
NC score	0.556089 (rank : 10)	θ value	1.87187e-05 (rank : 42)
Query Neighborhood Hits	436	Target Neighborhood Hits	249	Shared Neighborhood Hits	178
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRI52_HUMAN
NC score	0.548448 (rank : 11)	θ value	0.00390308 (rank : 112)
Query Neighborhood Hits	436	Target Neighborhood Hits	213	Shared Neighborhood Hits	164
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI22_HUMAN
NC score	0.545684 (rank : 12)	θ value	8.97725e-08 (rank : 14)
Query Neighborhood Hits	436	Target Neighborhood Hits	396	Shared Neighborhood Hits	196
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRIM4_HUMAN
NC score	0.544475 (rank : 13)	θ value	2.61198e-07 (rank : 18)
Query Neighborhood Hits	436	Target Neighborhood Hits	321	Shared Neighborhood Hits	194
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

ZN313_MOUSE
NC score	0.543132 (rank : 14)	θ value	7.1131e-05 (rank : 59)
Query Neighborhood Hits	436	Target Neighborhood Hits	273	Shared Neighborhood Hits	192
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

RN125_MOUSE
NC score	0.541729 (rank : 15)	θ value	0.000270298 (rank : 74)
Query Neighborhood Hits	436	Target Neighborhood Hits	220	Shared Neighborhood Hits	169
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RN125_HUMAN
NC score	0.539619 (rank : 16)	θ value	4.1701e-05 (rank : 48)
Query Neighborhood Hits	436	Target Neighborhood Hits	230	Shared Neighborhood Hits	170
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

TRIM5_HUMAN
NC score	0.538087 (rank : 17)	θ value	4.45536e-07 (rank : 22)
Query Neighborhood Hits	436	Target Neighborhood Hits	424	Shared Neighborhood Hits	197
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRI43_HUMAN
NC score	0.536159 (rank : 18)	θ value	1.69304e-06 (rank : 31)
Query Neighborhood Hits	436	Target Neighborhood Hits	341	Shared Neighborhood Hits	186
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI13_MOUSE
NC score	0.533958 (rank : 19)	θ value	0.00035302 (rank : 79)
Query Neighborhood Hits	436	Target Neighborhood Hits	282	Shared Neighborhood Hits	182
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI13_HUMAN
NC score	0.533682 (rank : 20)	θ value	0.000602161 (rank : 86)
Query Neighborhood Hits	436	Target Neighborhood Hits	274	Shared Neighborhood Hits	182
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI50_HUMAN
NC score	0.533434 (rank : 21)	θ value	2.61198e-07 (rank : 17)
Query Neighborhood Hits	436	Target Neighborhood Hits	294	Shared Neighborhood Hits	194
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

ZN313_HUMAN
NC score	0.532137 (rank : 22)	θ value	9.29e-05 (rank : 63)
Query Neighborhood Hits	436	Target Neighborhood Hits	264	Shared Neighborhood Hits	193
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

TRI50_MOUSE
NC score	0.532040 (rank : 23)	θ value	9.92553e-07 (rank : 28)
Query Neighborhood Hits	436	Target Neighborhood Hits	326	Shared Neighborhood Hits	203
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI35_HUMAN
NC score	0.530287 (rank : 24)	θ value	5.44631e-05 (rank : 57)
Query Neighborhood Hits	436	Target Neighborhood Hits	382	Shared Neighborhood Hits	193
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRIM6_MOUSE
NC score	0.527751 (rank : 25)	θ value	7.59969e-07 (rank : 27)
Query Neighborhood Hits	436	Target Neighborhood Hits	451	Shared Neighborhood Hits	199
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRI60_HUMAN
NC score	0.525619 (rank : 26)	θ value	2.21117e-06 (rank : 32)
Query Neighborhood Hits	436	Target Neighborhood Hits	357	Shared Neighborhood Hits	204
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRI35_MOUSE
NC score	0.524301 (rank : 27)	θ value	0.00035302 (rank : 80)
Query Neighborhood Hits	436	Target Neighborhood Hits	465	Shared Neighborhood Hits	196
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRIM6_HUMAN
NC score	0.521486 (rank : 28)	θ value	3.77169e-06 (rank : 35)
Query Neighborhood Hits	436	Target Neighborhood Hits	412	Shared Neighborhood Hits	192
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRI11_MOUSE
NC score	0.519904 (rank : 29)	θ value	6.87365e-08 (rank : 10)
Query Neighborhood Hits	436	Target Neighborhood Hits	329	Shared Neighborhood Hits	191
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI34_HUMAN
NC score	0.519648 (rank : 30)	θ value	5.81887e-07 (rank : 24)
Query Neighborhood Hits	436	Target Neighborhood Hits	416	Shared Neighborhood Hits	173
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

RO52_HUMAN
NC score	0.519420 (rank : 31)	θ value	4.45536e-07 (rank : 21)
Query Neighborhood Hits	436	Target Neighborhood Hits	419	Shared Neighborhood Hits	206
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

RO52_MOUSE
NC score	0.518967 (rank : 32)	θ value	2.36244e-08 (rank : 8)
Query Neighborhood Hits	436	Target Neighborhood Hits	360	Shared Neighborhood Hits	194
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TRI11_HUMAN
NC score	0.518656 (rank : 33)	θ value	8.97725e-08 (rank : 13)
Query Neighborhood Hits	436	Target Neighborhood Hits	316	Shared Neighborhood Hits	189
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI25_MOUSE
NC score	0.517190 (rank : 34)	θ value	5.81887e-07 (rank : 23)
Query Neighborhood Hits	436	Target Neighborhood Hits	446	Shared Neighborhood Hits	193
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI65_HUMAN
NC score	0.517187 (rank : 35)	θ value	0.21417 (rank : 195)
Query Neighborhood Hits	436	Target Neighborhood Hits	330	Shared Neighborhood Hits	194
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI68_MOUSE
NC score	0.514457 (rank : 36)	θ value	2.88788e-06 (rank : 33)
Query Neighborhood Hits	436	Target Neighborhood Hits	356	Shared Neighborhood Hits	194
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRI10_HUMAN
NC score	0.513850 (rank : 37)	θ value	2.44474e-05 (rank : 43)
Query Neighborhood Hits	436	Target Neighborhood Hits	315	Shared Neighborhood Hits	186
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI39_MOUSE
NC score	0.512298 (rank : 38)	θ value	7.59969e-07 (rank : 26)
Query Neighborhood Hits	436	Target Neighborhood Hits	691	Shared Neighborhood Hits	213
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI68_HUMAN
NC score	0.512164 (rank : 39)	θ value	4.92598e-06 (rank : 36)
Query Neighborhood Hits	436	Target Neighborhood Hits	267	Shared Neighborhood Hits	180
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TRI39_HUMAN
NC score	0.511842 (rank : 40)	θ value	7.59969e-07 (rank : 25)
Query Neighborhood Hits	436	Target Neighborhood Hits	693	Shared Neighborhood Hits	211
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI10_MOUSE
NC score	0.510002 (rank : 41)	θ value	3.19293e-05 (rank : 44)
Query Neighborhood Hits	436	Target Neighborhood Hits	285	Shared Neighborhood Hits	183
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI65_MOUSE
NC score	0.507185 (rank : 42)	θ value	0.21417 (rank : 196)
Query Neighborhood Hits	436	Target Neighborhood Hits	340	Shared Neighborhood Hits	191
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI17_HUMAN
NC score	0.506649 (rank : 43)	θ value	0.000121331 (rank : 65)
Query Neighborhood Hits	436	Target Neighborhood Hits	318	Shared Neighborhood Hits	187
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRI59_MOUSE
NC score	0.505626 (rank : 44)	θ value	0.00228821 (rank : 103)
Query Neighborhood Hits	436	Target Neighborhood Hits	292	Shared Neighborhood Hits	175
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRIM8_HUMAN
NC score	0.505039 (rank : 45)	θ value	9.29e-05 (rank : 61)
Query Neighborhood Hits	436	Target Neighborhood Hits	650	Shared Neighborhood Hits	194
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_MOUSE
NC score	0.504534 (rank : 46)	θ value	9.29e-05 (rank : 62)
Query Neighborhood Hits	436	Target Neighborhood Hits	674	Shared Neighborhood Hits	193
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRI59_HUMAN
NC score	0.503081 (rank : 47)	θ value	0.00228821 (rank : 102)
Query Neighborhood Hits	436	Target Neighborhood Hits	307	Shared Neighborhood Hits	175
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

PEX10_HUMAN
NC score	0.502683 (rank : 48)	θ value	0.00134147 (rank : 93)
Query Neighborhood Hits	436	Target Neighborhood Hits	255	Shared Neighborhood Hits	170
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

TRIM7_MOUSE
NC score	0.502518 (rank : 49)	θ value	0.000461057 (rank : 85)
Query Neighborhood Hits	436	Target Neighborhood Hits	358	Shared Neighborhood Hits	182
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRI62_MOUSE
NC score	0.501887 (rank : 50)	θ value	8.40245e-06 (rank : 37)
Query Neighborhood Hits	436	Target Neighborhood Hits	478	Shared Neighborhood Hits	189
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

RING1_HUMAN
NC score	0.501201 (rank : 51)	θ value	1.69304e-06 (rank : 30)
Query Neighborhood Hits	436	Target Neighborhood Hits	219	Shared Neighborhood Hits	157
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

TRI48_HUMAN
NC score	0.498299 (rank : 52)	θ value	0.00020696 (rank : 73)
Query Neighborhood Hits	436	Target Neighborhood Hits	192	Shared Neighborhood Hits	155
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

TRIM7_HUMAN
NC score	0.498288 (rank : 53)	θ value	0.000461057 (rank : 84)
Query Neighborhood Hits	436	Target Neighborhood Hits	336	Shared Neighborhood Hits	182
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRI60_MOUSE
NC score	0.496911 (rank : 54)	θ value	4.1701e-05 (rank : 53)
Query Neighborhood Hits	436	Target Neighborhood Hits	240	Shared Neighborhood Hits	162
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRI38_HUMAN
NC score	0.496093 (rank : 55)	θ value	0.000786445 (rank : 89)
Query Neighborhood Hits	436	Target Neighborhood Hits	373	Shared Neighborhood Hits	187
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

RING1_MOUSE
NC score	0.495671 (rank : 56)	θ value	1.29631e-06 (rank : 29)
Query Neighborhood Hits	436	Target Neighborhood Hits	220	Shared Neighborhood Hits	157
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

TRI25_HUMAN
NC score	0.493804 (rank : 57)	θ value	1.43324e-05 (rank : 39)
Query Neighborhood Hits	436	Target Neighborhood Hits	472	Shared Neighborhood Hits	196
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI62_HUMAN
NC score	0.492462 (rank : 58)	θ value	1.87187e-05 (rank : 40)
Query Neighborhood Hits	436	Target Neighborhood Hits	584	Shared Neighborhood Hits	193
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

RN166_MOUSE
NC score	0.491369 (rank : 59)	θ value	0.0252991 (rank : 142)
Query Neighborhood Hits	436	Target Neighborhood Hits	248	Shared Neighborhood Hits	178
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_HUMAN
NC score	0.491282 (rank : 60)	θ value	0.0252991 (rank : 141)
Query Neighborhood Hits	436	Target Neighborhood Hits	240	Shared Neighborhood Hits	173
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

TRI34_MOUSE
NC score	0.489309 (rank : 61)	θ value	5.44631e-05 (rank : 56)
Query Neighborhood Hits	436	Target Neighborhood Hits	332	Shared Neighborhood Hits	163
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI27_HUMAN
NC score	0.488744 (rank : 62)	θ value	3.77169e-06 (rank : 34)
Query Neighborhood Hits	436	Target Neighborhood Hits	273	Shared Neighborhood Hits	181
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI17_MOUSE
NC score	0.488358 (rank : 63)	θ value	0.000158464 (rank : 68)
Query Neighborhood Hits	436	Target Neighborhood Hits	620	Shared Neighborhood Hits	196
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

RN168_HUMAN
NC score	0.487374 (rank : 64)	θ value	0.00035302 (rank : 76)
Query Neighborhood Hits	436	Target Neighborhood Hits	370	Shared Neighborhood Hits	178
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

ZN179_HUMAN
NC score	0.486588 (rank : 65)	θ value	0.0252991 (rank : 144)
Query Neighborhood Hits	436	Target Neighborhood Hits	178	Shared Neighborhood Hits	146
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

TRI47_MOUSE
NC score	0.486556 (rank : 66)	θ value	3.19293e-05 (rank : 45)
Query Neighborhood Hits	436	Target Neighborhood Hits	295	Shared Neighborhood Hits	177
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

RING2_HUMAN
NC score	0.485523 (rank : 67)	θ value	4.45536e-07 (rank : 19)
Query Neighborhood Hits	436	Target Neighborhood Hits	201	Shared Neighborhood Hits	154
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
NC score	0.485454 (rank : 68)	θ value	4.45536e-07 (rank : 20)
Query Neighborhood Hits	436	Target Neighborhood Hits	199	Shared Neighborhood Hits	153
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

TRI27_MOUSE
NC score	0.482436 (rank : 69)	θ value	1.09739e-05 (rank : 38)
Query Neighborhood Hits	436	Target Neighborhood Hits	261	Shared Neighborhood Hits	177
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI49_HUMAN
NC score	0.479176 (rank : 70)	θ value	0.0113563 (rank : 128)
Query Neighborhood Hits	436	Target Neighborhood Hits	199	Shared Neighborhood Hits	146
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRI47_HUMAN
NC score	0.476119 (rank : 71)	θ value	0.000461057 (rank : 83)
Query Neighborhood Hits	436	Target Neighborhood Hits	286	Shared Neighborhood Hits	177
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRI32_HUMAN
NC score	0.473867 (rank : 72)	θ value	4.1701e-05 (rank : 50)
Query Neighborhood Hits	436	Target Neighborhood Hits	264	Shared Neighborhood Hits	154
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI32_MOUSE
NC score	0.473265 (rank : 73)	θ value	4.1701e-05 (rank : 51)
Query Neighborhood Hits	436	Target Neighborhood Hits	271	Shared Neighborhood Hits	155
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

RN168_MOUSE
NC score	0.472730 (rank : 74)	θ value	0.00020696 (rank : 70)
Query Neighborhood Hits	436	Target Neighborhood Hits	440	Shared Neighborhood Hits	193
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI41_HUMAN
NC score	0.467122 (rank : 75)	θ value	0.0148317 (rank : 133)
Query Neighborhood Hits	436	Target Neighborhood Hits	349	Shared Neighborhood Hits	168
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

RNF39_HUMAN
NC score	0.458180 (rank : 76)	θ value	0.00020696 (rank : 71)
Query Neighborhood Hits	436	Target Neighborhood Hits	200	Shared Neighborhood Hits	150
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

TRI15_HUMAN
NC score	0.455583 (rank : 77)	θ value	0.0736092 (rank : 171)
Query Neighborhood Hits	436	Target Neighborhood Hits	395	Shared Neighborhood Hits	171
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

RNF8_MOUSE
NC score	0.454004 (rank : 78)	θ value	5.44631e-05 (rank : 55)
Query Neighborhood Hits	436	Target Neighborhood Hits	618	Shared Neighborhood Hits	214
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

RN185_HUMAN
NC score	0.453256 (rank : 79)	θ value	0.00035302 (rank : 77)
Query Neighborhood Hits	436	Target Neighborhood Hits	213	Shared Neighborhood Hits	153
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
NC score	0.452347 (rank : 80)	θ value	0.00035302 (rank : 78)
Query Neighborhood Hits	436	Target Neighborhood Hits	211	Shared Neighborhood Hits	153
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RAG1_HUMAN
NC score	0.451049 (rank : 81)	θ value	4.1701e-05 (rank : 46)
Query Neighborhood Hits	436	Target Neighborhood Hits	203	Shared Neighborhood Hits	150
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RNF5_MOUSE
NC score	0.449332 (rank : 82)	θ value	0.000121331 (rank : 64)
Query Neighborhood Hits	436	Target Neighborhood Hits	206	Shared Neighborhood Hits	150
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

RNF5_HUMAN
NC score	0.449051 (rank : 83)	θ value	0.000158464 (rank : 67)
Query Neighborhood Hits	436	Target Neighborhood Hits	206	Shared Neighborhood Hits	152
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RAG1_MOUSE
NC score	0.444015 (rank : 84)	θ value	4.1701e-05 (rank : 47)
Query Neighborhood Hits	436	Target Neighborhood Hits	189	Shared Neighborhood Hits	149
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

RNF41_MOUSE
NC score	0.440191 (rank : 85)	θ value	0.00228821 (rank : 101)
Query Neighborhood Hits	436	Target Neighborhood Hits	224	Shared Neighborhood Hits	160
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_HUMAN
NC score	0.440062 (rank : 86)	θ value	0.00228821 (rank : 100)
Query Neighborhood Hits	436	Target Neighborhood Hits	226	Shared Neighborhood Hits	160
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

TRI63_MOUSE
NC score	0.438793 (rank : 87)	θ value	0.0193708 (rank : 136)
Query Neighborhood Hits	436	Target Neighborhood Hits	240	Shared Neighborhood Hits	143
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

BFAR_HUMAN
NC score	0.431804 (rank : 88)	θ value	0.279714 (rank : 197)
Query Neighborhood Hits	436	Target Neighborhood Hits	222	Shared Neighborhood Hits	161
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

TRI55_HUMAN
NC score	0.430343 (rank : 89)	θ value	0.0330416 (rank : 153)
Query Neighborhood Hits	436	Target Neighborhood Hits	292	Shared Neighborhood Hits	145
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRI63_HUMAN
NC score	0.430114 (rank : 90)	θ value	0.00869519 (rank : 120)
Query Neighborhood Hits	436	Target Neighborhood Hits	298	Shared Neighborhood Hits	146
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

BFAR_MOUSE
NC score	0.429379 (rank : 91)	θ value	0.279714 (rank : 198)
Query Neighborhood Hits	436	Target Neighborhood Hits	232	Shared Neighborhood Hits	157
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

RNF8_HUMAN
NC score	0.425989 (rank : 92)	θ value	0.000461057 (rank : 82)
Query Neighborhood Hits	436	Target Neighborhood Hits	622	Shared Neighborhood Hits	211
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RNF4_HUMAN
NC score	0.424374 (rank : 93)	θ value	0.0113563 (rank : 125)
Query Neighborhood Hits	436	Target Neighborhood Hits	212	Shared Neighborhood Hits	152
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

TRI54_HUMAN
NC score	0.421975 (rank : 94)	θ value	0.0961366 (rank : 178)
Query Neighborhood Hits	436	Target Neighborhood Hits	209	Shared Neighborhood Hits	144
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

RNF4_MOUSE
NC score	0.421245 (rank : 95)	θ value	0.0113563 (rank : 126)
Query Neighborhood Hits	436	Target Neighborhood Hits	212	Shared Neighborhood Hits	152
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

TRI54_MOUSE
NC score	0.420464 (rank : 96)	θ value	0.0961366 (rank : 179)
Query Neighborhood Hits	436	Target Neighborhood Hits	197	Shared Neighborhood Hits	141
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRAF6_MOUSE
NC score	0.408839 (rank : 97)	θ value	0.000270298 (rank : 75)
Query Neighborhood Hits	436	Target Neighborhood Hits	255	Shared Neighborhood Hits	167
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

TRAF6_HUMAN
NC score	0.405697 (rank : 98)	θ value	0.00020696 (rank : 72)
Query Neighborhood Hits	436	Target Neighborhood Hits	267	Shared Neighborhood Hits	167
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRIM2_HUMAN
NC score	0.404755 (rank : 99)	θ value	0.0193708 (rank : 137)
Query Neighborhood Hits	436	Target Neighborhood Hits	330	Shared Neighborhood Hits	187
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
NC score	0.403009 (rank : 100)	θ value	0.0193708 (rank : 138)
Query Neighborhood Hits	436	Target Neighborhood Hits	331	Shared Neighborhood Hits	186
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRI18_MOUSE
NC score	0.402729 (rank : 101)	θ value	0.000602161 (rank : 88)
Query Neighborhood Hits	436	Target Neighborhood Hits	292	Shared Neighborhood Hits	168
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRI18_HUMAN
NC score	0.402609 (rank : 102)	θ value	0.000602161 (rank : 87)
Query Neighborhood Hits	436	Target Neighborhood Hits	307	Shared Neighborhood Hits	168
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

RN146_HUMAN
NC score	0.399011 (rank : 103)	θ value	0.000158464 (rank : 66)
Query Neighborhood Hits	436	Target Neighborhood Hits	162	Shared Neighborhood Hits	128
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

TRIM3_MOUSE
NC score	0.398700 (rank : 104)	θ value	0.125558 (rank : 188)
Query Neighborhood Hits	436	Target Neighborhood Hits	351	Shared Neighborhood Hits	181
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRIM1_HUMAN
NC score	0.398421 (rank : 105)	θ value	0.00228821 (rank : 104)
Query Neighborhood Hits	436	Target Neighborhood Hits	345	Shared Neighborhood Hits	177
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM3_HUMAN
NC score	0.397455 (rank : 106)	θ value	0.163984 (rank : 191)
Query Neighborhood Hits	436	Target Neighborhood Hits	357	Shared Neighborhood Hits	184
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRIM1_MOUSE
NC score	0.395885 (rank : 107)	θ value	0.00228821 (rank : 105)
Query Neighborhood Hits	436	Target Neighborhood Hits	361	Shared Neighborhood Hits	180
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

RN146_MOUSE
NC score	0.395045 (rank : 108)	θ value	0.00020696 (rank : 69)
Query Neighborhood Hits	436	Target Neighborhood Hits	161	Shared Neighborhood Hits	127
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

TRI56_HUMAN
NC score	0.389315 (rank : 109)	θ value	0.0148317 (rank : 134)
Query Neighborhood Hits	436	Target Neighborhood Hits	339	Shared Neighborhood Hits	167
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI56_MOUSE
NC score	0.372115 (rank : 110)	θ value	0.0563607 (rank : 163)
Query Neighborhood Hits	436	Target Neighborhood Hits	255	Shared Neighborhood Hits	158
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

RAD18_MOUSE
NC score	0.371418 (rank : 111)	θ value	0.00134147 (rank : 95)
Query Neighborhood Hits	436	Target Neighborhood Hits	230	Shared Neighborhood Hits	141
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RFPL3_HUMAN
NC score	0.364989 (rank : 112)	θ value	0.47712 (rank : 226)
Query Neighborhood Hits	436	Target Neighborhood Hits	134	Shared Neighborhood Hits	104
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

SMRA3_HUMAN
NC score	0.364173 (rank : 113)	θ value	8.97725e-08 (rank : 12)
Query Neighborhood Hits	436	Target Neighborhood Hits	265	Shared Neighborhood Hits	181
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

MEFV_HUMAN
NC score	0.364140 (rank : 114)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	436	Target Neighborhood Hits	431	Shared Neighborhood Hits	111
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

TRI46_MOUSE
NC score	0.358515 (rank : 115)	θ value	0.00509761 (rank : 115)
Query Neighborhood Hits	436	Target Neighborhood Hits	287	Shared Neighborhood Hits	152
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

RAD18_HUMAN
NC score	0.357667 (rank : 116)	θ value	0.00134147 (rank : 94)
Query Neighborhood Hits	436	Target Neighborhood Hits	284	Shared Neighborhood Hits	149
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RFPL2_HUMAN
NC score	0.357490 (rank : 117)	θ value	0.279714 (rank : 205)
Query Neighborhood Hits	436	Target Neighborhood Hits	126	Shared Neighborhood Hits	98
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

TRI46_HUMAN
NC score	0.357432 (rank : 118)	θ value	0.00509761 (rank : 114)
Query Neighborhood Hits	436	Target Neighborhood Hits	291	Shared Neighborhood Hits	151
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

SMRA3_MOUSE
NC score	0.355417 (rank : 119)	θ value	4.0297e-08 (rank : 9)
Query Neighborhood Hits	436	Target Neighborhood Hits	267	Shared Neighborhood Hits	179
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

RFPL1_HUMAN
NC score	0.353111 (rank : 120)	θ value	0.21417 (rank : 194)
Query Neighborhood Hits	436	Target Neighborhood Hits	119	Shared Neighborhood Hits	92
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

CHFR_HUMAN
NC score	0.336926 (rank : 121)	θ value	1.06291 (rank : 248)
Query Neighborhood Hits	436	Target Neighborhood Hits	255	Shared Neighborhood Hits	161
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_MOUSE
NC score	0.336582 (rank : 122)	θ value	1.06291 (rank : 249)
Query Neighborhood Hits	436	Target Neighborhood Hits	264	Shared Neighborhood Hits	166
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

UHRF2_HUMAN
NC score	0.334579 (rank : 123)	θ value	0.00134147 (rank : 96)
Query Neighborhood Hits	436	Target Neighborhood Hits	269	Shared Neighborhood Hits	161
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

MEFV_MOUSE
NC score	0.333668 (rank : 124)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	436	Target Neighborhood Hits	236	Shared Neighborhood Hits	108
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

TRI37_HUMAN
NC score	0.332836 (rank : 125)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	436	Target Neighborhood Hits	307	Shared Neighborhood Hits	149
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
NC score	0.332692 (rank : 126)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	436	Target Neighborhood Hits	316	Shared Neighborhood Hits	149
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

CM007_MOUSE
NC score	0.332237 (rank : 127)	θ value	5.44631e-05 (rank : 54)
Query Neighborhood Hits	436	Target Neighborhood Hits	416	Shared Neighborhood Hits	140
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

TRIM9_HUMAN
NC score	0.331032 (rank : 128)	θ value	0.0736092 (rank : 172)
Query Neighborhood Hits	436	Target Neighborhood Hits	294	Shared Neighborhood Hits	143
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

UHRF2_MOUSE
NC score	0.330414 (rank : 129)	θ value	0.00134147 (rank : 97)
Query Neighborhood Hits	436	Target Neighborhood Hits	275	Shared Neighborhood Hits	160
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

TRIM9_MOUSE
NC score	0.330101 (rank : 130)	θ value	0.0736092 (rank : 173)
Query Neighborhood Hits	436	Target Neighborhood Hits	274	Shared Neighborhood Hits	141
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

TRI14_HUMAN
NC score	0.325135 (rank : 131)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	436	Target Neighborhood Hits	143	Shared Neighborhood Hits	81
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

DTX3_MOUSE
NC score	0.323743 (rank : 132)	θ value	0.0330416 (rank : 147)
Query Neighborhood Hits	436	Target Neighborhood Hits	202	Shared Neighborhood Hits	146
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

TRI14_MOUSE
NC score	0.322840 (rank : 133)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	436	Target Neighborhood Hits	137	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

DTX3_HUMAN
NC score	0.317797 (rank : 134)	θ value	0.0330416 (rank : 146)
Query Neighborhood Hits	436	Target Neighborhood Hits	198	Shared Neighborhood Hits	141
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

TRI36_HUMAN
NC score	0.310772 (rank : 135)	θ value	0.813845 (rank : 245)
Query Neighborhood Hits	436	Target Neighborhood Hits	282	Shared Neighborhood Hits	141
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

ERMAP_HUMAN
NC score	0.309481 (rank : 136)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	436	Target Neighborhood Hits	155	Shared Neighborhood Hits	60
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

TRI36_MOUSE
NC score	0.307848 (rank : 137)	θ value	0.47712 (rank : 230)
Query Neighborhood Hits	436	Target Neighborhood Hits	266	Shared Neighborhood Hits	138
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

CM007_HUMAN
NC score	0.306312 (rank : 138)	θ value	9.29e-05 (rank : 60)
Query Neighborhood Hits	436	Target Neighborhood Hits	422	Shared Neighborhood Hits	132
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

TRI44_MOUSE
NC score	0.304107 (rank : 139)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	436	Target Neighborhood Hits	327	Shared Neighborhood Hits	94
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

RFWD2_MOUSE
NC score	0.302184 (rank : 140)	θ value	0.00298849 (rank : 108)
Query Neighborhood Hits	436	Target Neighborhood Hits	535	Shared Neighborhood Hits	193
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

R113B_HUMAN
NC score	0.300717 (rank : 141)	θ value	0.21417 (rank : 193)
Query Neighborhood Hits	436	Target Neighborhood Hits	165	Shared Neighborhood Hits	133
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

RFWD2_HUMAN
NC score	0.300293 (rank : 142)	θ value	0.00298849 (rank : 107)
Query Neighborhood Hits	436	Target Neighborhood Hits	518	Shared Neighborhood Hits	189
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

TRI44_HUMAN
NC score	0.298222 (rank : 143)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	436	Target Neighborhood Hits	393	Shared Neighborhood Hits	101
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

R113A_HUMAN
NC score	0.295016 (rank : 144)	θ value	0.279714 (rank : 204)
Query Neighborhood Hits	436	Target Neighborhood Hits	177	Shared Neighborhood Hits	133
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

TRI16_MOUSE
NC score	0.294949 (rank : 145)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	436	Target Neighborhood Hits	196	Shared Neighborhood Hits	78
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

BSPRY_MOUSE
NC score	0.292010 (rank : 146)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	436	Target Neighborhood Hits	163	Shared Neighborhood Hits	75
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

TRI16_HUMAN
NC score	0.287565 (rank : 147)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	436	Target Neighborhood Hits	231	Shared Neighborhood Hits	86
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

UHRF1_MOUSE
NC score	0.286882 (rank : 148)	θ value	0.00228821 (rank : 106)
Query Neighborhood Hits	436	Target Neighborhood Hits	278	Shared Neighborhood Hits	158
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

ERMAP_MOUSE
NC score	0.285642 (rank : 149)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	436	Target Neighborhood Hits	231	Shared Neighborhood Hits	57
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

BSPRY_HUMAN
NC score	0.285609 (rank : 150)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	436	Target Neighborhood Hits	115	Shared Neighborhood Hits	68
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

UHRF1_HUMAN
NC score	0.277631 (rank : 151)	θ value	0.0431538 (rank : 154)
Query Neighborhood Hits	436	Target Neighborhood Hits	272	Shared Neighborhood Hits	159
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

TRI29_MOUSE
NC score	0.276957 (rank : 152)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	436	Target Neighborhood Hits	306	Shared Neighborhood Hits	86
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

BT1A1_MOUSE
NC score	0.274132 (rank : 153)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	436	Target Neighborhood Hits	252	Shared Neighborhood Hits	61
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

TRI29_HUMAN
NC score	0.272960 (rank : 154)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	436	Target Neighborhood Hits	273	Shared Neighborhood Hits	83
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

PZRN4_HUMAN
NC score	0.272698 (rank : 155)	θ value	7.1131e-05 (rank : 58)
Query Neighborhood Hits	436	Target Neighborhood Hits	438	Shared Neighborhood Hits	178
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

BT3A3_HUMAN
NC score	0.271974 (rank : 156)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	436	Target Neighborhood Hits	233	Shared Neighborhood Hits	61
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

PZRN3_MOUSE
NC score	0.270513 (rank : 157)	θ value	0.00390308 (rank : 110)
Query Neighborhood Hits	436	Target Neighborhood Hits	447	Shared Neighborhood Hits	180
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

BT2A2_HUMAN
NC score	0.270314 (rank : 158)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	436	Target Neighborhood Hits	191	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

PZRN3_HUMAN
NC score	0.270074 (rank : 159)	θ value	0.00390308 (rank : 109)
Query Neighborhood Hits	436	Target Neighborhood Hits	461	Shared Neighborhood Hits	181
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

BT3A1_HUMAN
NC score	0.269998 (rank : 160)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	436	Target Neighborhood Hits	229	Shared Neighborhood Hits	61
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

BT1A1_HUMAN
NC score	0.269954 (rank : 161)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	436	Target Neighborhood Hits	322	Shared Neighborhood Hits	61
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

LNX1_HUMAN
NC score	0.268049 (rank : 162)	θ value	0.0113563 (rank : 121)
Query Neighborhood Hits	436	Target Neighborhood Hits	379	Shared Neighborhood Hits	169
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

BTNL3_HUMAN
NC score	0.267641 (rank : 163)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	436	Target Neighborhood Hits	143	Shared Neighborhood Hits	57
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

BTNL9_HUMAN
NC score	0.267545 (rank : 164)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	436	Target Neighborhood Hits	125	Shared Neighborhood Hits	56
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

LNX2_HUMAN
NC score	0.264936 (rank : 165)	θ value	0.0148317 (rank : 132)
Query Neighborhood Hits	436	Target Neighborhood Hits	389	Shared Neighborhood Hits	172
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

TRAF4_HUMAN
NC score	0.262370 (rank : 166)	θ value	0.279714 (rank : 206)
Query Neighborhood Hits	436	Target Neighborhood Hits	373	Shared Neighborhood Hits	149
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

LNX1_MOUSE
NC score	0.261753 (rank : 167)	θ value	0.0113563 (rank : 122)
Query Neighborhood Hits	436	Target Neighborhood Hits	377	Shared Neighborhood Hits	161
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

RN183_HUMAN
NC score	0.261303 (rank : 168)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	436	Target Neighborhood Hits	126	Shared Neighborhood Hits	102
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

BT2A1_HUMAN
NC score	0.261295 (rank : 169)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	436	Target Neighborhood Hits	185	Shared Neighborhood Hits	59
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

LNX2_MOUSE
NC score	0.261156 (rank : 170)	θ value	0.0113563 (rank : 123)
Query Neighborhood Hits	436	Target Neighborhood Hits	407	Shared Neighborhood Hits	173
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

BT2A3_HUMAN
NC score	0.260904 (rank : 171)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	436	Target Neighborhood Hits	195	Shared Neighborhood Hits	56
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

RN169_HUMAN
NC score	0.260393 (rank : 172)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	436	Target Neighborhood Hits	203	Shared Neighborhood Hits	117
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

BTNL8_HUMAN
NC score	0.258411 (rank : 173)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	436	Target Neighborhood Hits	177	Shared Neighborhood Hits	59
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

TRAF5_MOUSE
NC score	0.258060 (rank : 174)	θ value	2.36792 (rank : 300)
Query Neighborhood Hits	436	Target Neighborhood Hits	355	Shared Neighborhood Hits	141
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

MCPH1_MOUSE
NC score	0.254805 (rank : 175)	θ value	3.29651e-10 (rank : 4)
Query Neighborhood Hits	436	Target Neighborhood Hits	116	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

SPRY4_MOUSE
NC score	0.251581 (rank : 176)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	436	Target Neighborhood Hits	82	Shared Neighborhood Hits	58
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TRAF5_HUMAN
NC score	0.248351 (rank : 177)	θ value	0.279714 (rank : 207)
Query Neighborhood Hits	436	Target Neighborhood Hits	396	Shared Neighborhood Hits	134
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

TRAF2_MOUSE
NC score	0.244610 (rank : 178)	θ value	0.00665767 (rank : 117)
Query Neighborhood Hits	436	Target Neighborhood Hits	394	Shared Neighborhood Hits	126
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

RN141_HUMAN
NC score	0.244568 (rank : 179)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	436	Target Neighborhood Hits	199	Shared Neighborhood Hits	139
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

SPRY4_HUMAN
NC score	0.244026 (rank : 180)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	436	Target Neighborhood Hits	79	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

RN141_MOUSE
NC score	0.243842 (rank : 181)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	436	Target Neighborhood Hits	200	Shared Neighborhood Hits	139
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

MCPH1_HUMAN
NC score	0.243378 (rank : 182)	θ value	1.80886e-08 (rank : 6)
Query Neighborhood Hits	436	Target Neighborhood Hits	85	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NEM0, Q66GU1, Q9H9C7	Gene names	MCPH1
Domain Architecture
Description	Microcephalin.

TRAF2_HUMAN
NC score	0.242256 (rank : 183)	θ value	0.00390308 (rank : 111)
Query Neighborhood Hits	436	Target Neighborhood Hits	402	Shared Neighborhood Hits	124
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

BIRC7_HUMAN
NC score	0.238307 (rank : 184)	θ value	0.813845 (rank : 238)
Query Neighborhood Hits	436	Target Neighborhood Hits	185	Shared Neighborhood Hits	140
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

TOPRS_MOUSE
NC score	0.235427 (rank : 185)	θ value	1.81305 (rank : 281)
Query Neighborhood Hits	436	Target Neighborhood Hits	263	Shared Neighborhood Hits	131
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_HUMAN
NC score	0.234744 (rank : 186)	θ value	1.81305 (rank : 280)
Query Neighborhood Hits	436	Target Neighborhood Hits	286	Shared Neighborhood Hits	135
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRI42_HUMAN
NC score	0.232312 (rank : 187)	θ value	5.27518 (rank : 371)
Query Neighborhood Hits	436	Target Neighborhood Hits	283	Shared Neighborhood Hits	106
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRAF3_MOUSE
NC score	0.232205 (rank : 188)	θ value	0.125558 (rank : 187)
Query Neighborhood Hits	436	Target Neighborhood Hits	476	Shared Neighborhood Hits	140
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

RN183_MOUSE
NC score	0.229358 (rank : 189)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	436	Target Neighborhood Hits	119	Shared Neighborhood Hits	97
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

TRAF3_HUMAN
NC score	0.228383 (rank : 190)	θ value	0.125558 (rank : 186)
Query Neighborhood Hits	436	Target Neighborhood Hits	463	Shared Neighborhood Hits	137
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

NHLC1_MOUSE
NC score	0.227941 (rank : 191)	θ value	0.125558 (rank : 184)
Query Neighborhood Hits	436	Target Neighborhood Hits	103	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

TRI42_MOUSE
NC score	0.227365 (rank : 192)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	436	Target Neighborhood Hits	316	Shared Neighborhood Hits	114
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

RC3H1_MOUSE
NC score	0.227364 (rank : 193)	θ value	0.0563607 (rank : 160)
Query Neighborhood Hits	436	Target Neighborhood Hits	244	Shared Neighborhood Hits	127
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

PCGF6_MOUSE
NC score	0.226638 (rank : 194)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	436	Target Neighborhood Hits	163	Shared Neighborhood Hits	121
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF6_HUMAN
NC score	0.222115 (rank : 195)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	436	Target Neighborhood Hits	178	Shared Neighborhood Hits	123
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

NHLC1_HUMAN
NC score	0.219401 (rank : 196)	θ value	0.0563607 (rank : 158)
Query Neighborhood Hits	436	Target Neighborhood Hits	91	Shared Neighborhood Hits	66
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

RC3H1_HUMAN
NC score	0.218458 (rank : 197)	θ value	0.0563607 (rank : 159)
Query Neighborhood Hits	436	Target Neighborhood Hits	433	Shared Neighborhood Hits	132
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

BARD1_HUMAN
NC score	0.212134 (rank : 198)	θ value	3.89403e-11 (rank : 3)
Query Neighborhood Hits	436	Target Neighborhood Hits	427	Shared Neighborhood Hits	109
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BARD1_MOUSE
NC score	0.209665 (rank : 199)	θ value	7.34386e-10 (rank : 5)
Query Neighborhood Hits	436	Target Neighborhood Hits	411	Shared Neighborhood Hits	102
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

DTX3L_HUMAN
NC score	0.202662 (rank : 200)	θ value	3.0926 (rank : 306)
Query Neighborhood Hits	436	Target Neighborhood Hits	187	Shared Neighborhood Hits	117
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

PCGF2_HUMAN
NC score	0.202401 (rank : 201)	θ value	3.0926 (rank : 314)
Query Neighborhood Hits	436	Target Neighborhood Hits	222	Shared Neighborhood Hits	112
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
NC score	0.201869 (rank : 202)	θ value	3.0926 (rank : 315)
Query Neighborhood Hits	436	Target Neighborhood Hits	213	Shared Neighborhood Hits	110
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

TRAF7_MOUSE
NC score	0.200325 (rank : 203)	θ value	0.0252991 (rank : 143)
Query Neighborhood Hits	436	Target Neighborhood Hits	470	Shared Neighborhood Hits	168
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

TRAF7_HUMAN
NC score	0.199100 (rank : 204)	θ value	0.0330416 (rank : 152)
Query Neighborhood Hits	436	Target Neighborhood Hits	482	Shared Neighborhood Hits	175
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

PML_MOUSE
NC score	0.198624 (rank : 205)	θ value	3.0926 (rank : 319)
Query Neighborhood Hits	436	Target Neighborhood Hits	246	Shared Neighborhood Hits	122
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

PML_HUMAN
NC score	0.196854 (rank : 206)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	436	Target Neighborhood Hits	248	Shared Neighborhood Hits	113
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

RBBP6_MOUSE
NC score	0.196329 (rank : 207)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	436	Target Neighborhood Hits	1014	Shared Neighborhood Hits	210
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

PCGF4_HUMAN
NC score	0.192650 (rank : 208)	θ value	6.88961 (rank : 394)
Query Neighborhood Hits	436	Target Neighborhood Hits	161	Shared Neighborhood Hits	112
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

TRI45_HUMAN
NC score	0.192290 (rank : 209)	θ value	5.27518 (rank : 372)
Query Neighborhood Hits	436	Target Neighborhood Hits	155	Shared Neighborhood Hits	93
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

PCGF4_MOUSE
NC score	0.191548 (rank : 210)	θ value	6.88961 (rank : 395)
Query Neighborhood Hits	436	Target Neighborhood Hits	163	Shared Neighborhood Hits	111
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

TRI45_MOUSE
NC score	0.185450 (rank : 211)	θ value	3.0926 (rank : 324)
Query Neighborhood Hits	436	Target Neighborhood Hits	155	Shared Neighborhood Hits	86
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

CBLC_HUMAN
NC score	0.185103 (rank : 212)	θ value	0.47712 (rank : 220)
Query Neighborhood Hits	436	Target Neighborhood Hits	173	Shared Neighborhood Hits	115
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

CBLC_MOUSE
NC score	0.181791 (rank : 213)	θ value	0.0961366 (rank : 174)
Query Neighborhood Hits	436	Target Neighborhood Hits	186	Shared Neighborhood Hits	118
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

RBBP6_HUMAN
NC score	0.181168 (rank : 214)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	436	Target Neighborhood Hits	1135	Shared Neighborhood Hits	210
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

TRAF4_MOUSE
NC score	0.178456 (rank : 215)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	436	Target Neighborhood Hits	338	Shared Neighborhood Hits	112
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

AMFR2_HUMAN
NC score	0.176325 (rank : 216)	θ value	6.88961 (rank : 374)
Query Neighborhood Hits	436	Target Neighborhood Hits	219	Shared Neighborhood Hits	123
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

MNAB_HUMAN
NC score	0.174015 (rank : 217)	θ value	0.279714 (rank : 202)
Query Neighborhood Hits	436	Target Neighborhood Hits	196	Shared Neighborhood Hits	105
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

CBL_HUMAN
NC score	0.172023 (rank : 218)	θ value	2.36792 (rank : 285)
Query Neighborhood Hits	436	Target Neighborhood Hits	353	Shared Neighborhood Hits	149
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

MNAB_MOUSE
NC score	0.171836 (rank : 219)	θ value	0.279714 (rank : 203)
Query Neighborhood Hits	436	Target Neighborhood Hits	231	Shared Neighborhood Hits	104
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

CBL_MOUSE
NC score	0.170745 (rank : 220)	θ value	2.36792 (rank : 286)
Query Neighborhood Hits	436	Target Neighborhood Hits	426	Shared Neighborhood Hits	153
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

TIF1G_HUMAN
NC score	0.169859 (rank : 221)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	436	Target Neighborhood Hits	410	Shared Neighborhood Hits	115
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
NC score	0.167553 (rank : 222)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	436	Target Neighborhood Hits	498	Shared Neighborhood Hits	119
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

AMFR_MOUSE
NC score	0.161412 (rank : 223)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	436	Target Neighborhood Hits	208	Shared Neighborhood Hits	116
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

CBLB_MOUSE
NC score	0.160814 (rank : 224)	θ value	2.36792 (rank : 284)
Query Neighborhood Hits	436	Target Neighborhood Hits	277	Shared Neighborhood Hits	131
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CBLB_HUMAN
NC score	0.160100 (rank : 225)	θ value	2.36792 (rank : 283)
Query Neighborhood Hits	436	Target Neighborhood Hits	261	Shared Neighborhood Hits	130
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

SIAH2_MOUSE
NC score	0.154008 (rank : 226)	θ value	0.0330416 (rank : 151)
Query Neighborhood Hits	436	Target Neighborhood Hits	101	Shared Neighborhood Hits	62
SwissProt Accessions	Q06986	Gene names	Siah2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (mSiah2).

SIAH2_HUMAN
NC score	0.153353 (rank : 227)	θ value	0.0330416 (rank : 150)
Query Neighborhood Hits	436	Target Neighborhood Hits	94	Shared Neighborhood Hits	60
SwissProt Accessions	O43255, O43270	Gene names	SIAH2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (hSiah2).

TIF1B_HUMAN
NC score	0.143012 (rank : 228)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	436	Target Neighborhood Hits	312	Shared Neighborhood Hits	98
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

RN152_MOUSE
NC score	0.141653 (rank : 229)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	436	Target Neighborhood Hits	109	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

TIF1B_MOUSE
NC score	0.140264 (rank : 230)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	436	Target Neighborhood Hits	276	Shared Neighborhood Hits	93
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

RN152_HUMAN
NC score	0.132178 (rank : 231)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	436	Target Neighborhood Hits	107	Shared Neighborhood Hits	69
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

BRE1B_MOUSE
NC score	0.126248 (rank : 232)	θ value	0.365318 (rank : 211)
Query Neighborhood Hits	436	Target Neighborhood Hits	970	Shared Neighborhood Hits	166
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

BRE1B_HUMAN
NC score	0.124367 (rank : 233)	θ value	0.365318 (rank : 210)
Query Neighborhood Hits	436	Target Neighborhood Hits	1040	Shared Neighborhood Hits	177
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

SIA1B_MOUSE
NC score	0.123485 (rank : 234)	θ value	3.0926 (rank : 321)
Query Neighborhood Hits	436	Target Neighborhood Hits	69	Shared Neighborhood Hits	52
SwissProt Accessions	Q06985, Q7TPV6	Gene names	Siah1b
Domain Architecture
Description	Ubiquitin ligase SIAH1B (EC 6.3.2.-) (Seven in absentia homolog 1b) (Siah1b) (Siah-1b).

SIAH1_HUMAN
NC score	0.122830 (rank : 235)	θ value	3.0926 (rank : 322)
Query Neighborhood Hits	436	Target Neighborhood Hits	72	Shared Neighborhood Hits	53
SwissProt Accessions	Q8IUQ4, O43269, Q92880	Gene names	SIAH1, HUMSIAH
Domain Architecture
Description	Ubiquitin ligase SIAH1 (EC 6.3.2.-) (Seven in absentia homolog 1) (Siah-1) (Siah-1a).

SIA1A_MOUSE
NC score	0.122092 (rank : 236)	θ value	3.0926 (rank : 320)
Query Neighborhood Hits	436	Target Neighborhood Hits	72	Shared Neighborhood Hits	53
SwissProt Accessions	P61092, Q06984	Gene names	Siah1a
Domain Architecture
Description	Ubiquitin ligase SIAH1A (EC 6.3.2.-) (Seven in absentia homolog 1a) (Siah1a) (Siah-1a) (mSiah-1a).

DSPP_HUMAN
NC score	0.120293 (rank : 237)	θ value	0.00509761 (rank : 113)
Query Neighborhood Hits	436	Target Neighborhood Hits	645	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

DMP1_MOUSE
NC score	0.118862 (rank : 238)	θ value	0.00102713 (rank : 90)
Query Neighborhood Hits	436	Target Neighborhood Hits	498	Shared Neighborhood Hits	70
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

DSPP_MOUSE
NC score	0.118780 (rank : 239)	θ value	0.00175202 (rank : 98)
Query Neighborhood Hits	436	Target Neighborhood Hits	491	Shared Neighborhood Hits	61
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

DMP1_HUMAN
NC score	0.117392 (rank : 240)	θ value	0.0563607 (rank : 157)
Query Neighborhood Hits	436	Target Neighborhood Hits	491	Shared Neighborhood Hits	77
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

BRE1A_HUMAN
NC score	0.111980 (rank : 241)	θ value	0.279714 (rank : 200)
Query Neighborhood Hits	436	Target Neighborhood Hits	1071	Shared Neighborhood Hits	170
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

UB7I3_MOUSE
NC score	0.111868 (rank : 242)	θ value	8.99809 (rank : 436)
Query Neighborhood Hits	436	Target Neighborhood Hits	131	Shared Neighborhood Hits	74
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

TIF1A_HUMAN
NC score	0.110463 (rank : 243)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	436	Target Neighborhood Hits	327	Shared Neighborhood Hits	96
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

RNF34_MOUSE
NC score	0.110003 (rank : 244)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	436	Target Neighborhood Hits	160	Shared Neighborhood Hits	86
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

BRE1A_MOUSE
NC score	0.109712 (rank : 245)	θ value	0.279714 (rank : 201)
Query Neighborhood Hits	436	Target Neighborhood Hits	1025	Shared Neighborhood Hits	158
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

NPBL_MOUSE
NC score	0.108986 (rank : 246)	θ value	0.00102713 (rank : 92)
Query Neighborhood Hits	436	Target Neighborhood Hits	1041	Shared Neighborhood Hits	102
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

TRAIP_HUMAN
NC score	0.108319 (rank : 247)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	436	Target Neighborhood Hits	780	Shared Neighborhood Hits	117
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

NIPBL_HUMAN
NC score	0.107857 (rank : 248)	θ value	0.00228821 (rank : 99)
Query Neighborhood Hits	436	Target Neighborhood Hits	1311	Shared Neighborhood Hits	119
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

RKHD1_HUMAN
NC score	0.107826 (rank : 249)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	436	Target Neighborhood Hits	163	Shared Neighborhood Hits	70
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

RNF34_HUMAN
NC score	0.107222 (rank : 250)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	436	Target Neighborhood Hits	153	Shared Neighborhood Hits	84
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RNF32_HUMAN
NC score	0.106410 (rank : 251)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	436	Target Neighborhood Hits	133	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

PEX2_MOUSE
NC score	0.105031 (rank : 252)	θ value	5.27518 (rank : 363)
Query Neighborhood Hits	436	Target Neighborhood Hits	57	Shared Neighborhood Hits	50
SwissProt Accessions	P55098, O35467	Gene names	Pxmp3, Paf1, Pex2, Pmp35
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3).

IWS1_HUMAN
NC score	0.103415 (rank : 253)	θ value	0.0330416 (rank : 148)
Query Neighborhood Hits	436	Target Neighborhood Hits	1241	Shared Neighborhood Hits	123
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NEUL1_HUMAN
NC score	0.103397 (rank : 254)	θ value	6.88961 (rank : 391)
Query Neighborhood Hits	436	Target Neighborhood Hits	114	Shared Neighborhood Hits	64
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

MIB1_MOUSE
NC score	0.103168 (rank : 255)	θ value	0.00869519 (rank : 119)
Query Neighborhood Hits	436	Target Neighborhood Hits	471	Shared Neighborhood Hits	105
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

MIB1_HUMAN
NC score	0.103101 (rank : 256)	θ value	0.00869519 (rank : 118)
Query Neighborhood Hits	436	Target Neighborhood Hits	470	Shared Neighborhood Hits	105
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

RNF26_HUMAN
NC score	0.102685 (rank : 257)	θ value	8.99809 (rank : 432)
Query Neighborhood Hits	436	Target Neighborhood Hits	95	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

MGRN1_MOUSE
NC score	0.102659 (rank : 258)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	436	Target Neighborhood Hits	149	Shared Neighborhood Hits	87
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

MGRN1_HUMAN
NC score	0.102583 (rank : 259)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	436	Target Neighborhood Hits	192	Shared Neighborhood Hits	95
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

NEURL_MOUSE
NC score	0.100890 (rank : 260)	θ value	6.88961 (rank : 392)
Query Neighborhood Hits	436	Target Neighborhood Hits	106	Shared Neighborhood Hits	62
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

TP53B_MOUSE
NC score	0.100136 (rank : 261)	θ value	0.0563607 (rank : 162)
Query Neighborhood Hits	436	Target Neighborhood Hits	644	Shared Neighborhood Hits	84
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

UB7I3_HUMAN
NC score	0.099191 (rank : 262)	θ value	8.99809 (rank : 435)
Query Neighborhood Hits	436	Target Neighborhood Hits	136	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

MKRN4_HUMAN
NC score	0.099150 (rank : 263)	θ value	1.06291 (rank : 255)
Query Neighborhood Hits	436	Target Neighborhood Hits	147	Shared Neighborhood Hits	79
SwissProt Accessions	Q13434	Gene names	MKRN4, RNF64, ZNF127L1
Domain Architecture	No domain graphic available
Description	Makorin-4 (Zinc finger protein 127-Xp) (ZNF127-Xp) (RING finger protein 64).

TIF1A_MOUSE
NC score	0.097731 (rank : 264)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	436	Target Neighborhood Hits	307	Shared Neighborhood Hits	88
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TRAIP_MOUSE
NC score	0.096729 (rank : 265)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	436	Target Neighborhood Hits	745	Shared Neighborhood Hits	109
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

ARD1_MOUSE
NC score	0.095995 (rank : 266)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	436	Target Neighborhood Hits	573	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

TP53B_HUMAN
NC score	0.095781 (rank : 267)	θ value	0.0563607 (rank : 161)
Query Neighborhood Hits	436	Target Neighborhood Hits	413	Shared Neighborhood Hits	64
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

RNF32_MOUSE
NC score	0.095073 (rank : 268)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	436	Target Neighborhood Hits	129	Shared Neighborhood Hits	61
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

IWS1_MOUSE
NC score	0.094340 (rank : 269)	θ value	0.0736092 (rank : 169)
Query Neighborhood Hits	436	Target Neighborhood Hits	1258	Shared Neighborhood Hits	116
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

BIRC8_HUMAN
NC score	0.093228 (rank : 270)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	436	Target Neighborhood Hits	121	Shared Neighborhood Hits	79
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

RFC1_HUMAN
NC score	0.092756 (rank : 271)	θ value	0.000461057 (rank : 81)
Query Neighborhood Hits	436	Target Neighborhood Hits	352	Shared Neighborhood Hits	50
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

ARD1_HUMAN
NC score	0.091921 (rank : 272)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	436	Target Neighborhood Hits	621	Shared Neighborhood Hits	76
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

PEX2_HUMAN
NC score	0.090231 (rank : 273)	θ value	2.36792 (rank : 294)
Query Neighborhood Hits	436	Target Neighborhood Hits	42	Shared Neighborhood Hits	35
SwissProt Accessions	P28328, Q567S6, Q9BW41	Gene names	PXMP3, PAF1, PEX2, PMP3, PMP35, RNF72
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3) (35 kDa peroxisomal membrane protein) (RING finger protein 72).

RN123_MOUSE
NC score	0.089812 (rank : 274)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	436	Target Neighborhood Hits	174	Shared Neighborhood Hits	111
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN123_HUMAN
NC score	0.089566 (rank : 275)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	436	Target Neighborhood Hits	175	Shared Neighborhood Hits	109
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

ZN364_HUMAN
NC score	0.087924 (rank : 276)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	436	Target Neighborhood Hits	140	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

RFFL_HUMAN
NC score	0.086838 (rank : 277)	θ value	2.36792 (rank : 298)
Query Neighborhood Hits	436	Target Neighborhood Hits	175	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RN126_MOUSE
NC score	0.085797 (rank : 278)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	436	Target Neighborhood Hits	143	Shared Neighborhood Hits	76
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

MIB2_HUMAN
NC score	0.083574 (rank : 279)	θ value	1.38821 (rank : 264)
Query Neighborhood Hits	436	Target Neighborhood Hits	438	Shared Neighborhood Hits	90
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

ZN364_MOUSE
NC score	0.082485 (rank : 280)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	436	Target Neighborhood Hits	140	Shared Neighborhood Hits	69
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

FSD1L_MOUSE
NC score	0.082428 (rank : 281)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	436	Target Neighborhood Hits	78	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BYN5, Q3USW7	Gene names	Fsd1l, Ccdc10, Csdufd1, Fsd1nl
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

PJA1_HUMAN
NC score	0.082421 (rank : 282)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	436	Target Neighborhood Hits	159	Shared Neighborhood Hits	66
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

MAT1_MOUSE
NC score	0.081974 (rank : 283)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	436	Target Neighborhood Hits	217	Shared Neighborhood Hits	46
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

BRAP_HUMAN
NC score	0.081885 (rank : 284)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	436	Target Neighborhood Hits	560	Shared Neighborhood Hits	88
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

APC11_MOUSE
NC score	0.081584 (rank : 285)	θ value	0.47712 (rank : 218)
Query Neighborhood Hits	436	Target Neighborhood Hits	75	Shared Neighborhood Hits	22
SwissProt Accessions	Q9CPX9, Q3UWH1, Q9CTG0	Gene names	Anapc11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11).

MKRN1_HUMAN
NC score	0.081025 (rank : 286)	θ value	4.03905 (rank : 333)
Query Neighborhood Hits	436	Target Neighborhood Hits	141	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UHC7, Q6GSF1, Q9H0G0, Q9UEZ7	Gene names	MKRN1, RNF61
Domain Architecture
Description	Makorin-1 (RING finger protein 61).

BRAP_MOUSE
NC score	0.080307 (rank : 287)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	436	Target Neighborhood Hits	409	Shared Neighborhood Hits	76
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

MAT1_HUMAN
NC score	0.079090 (rank : 288)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	436	Target Neighborhood Hits	179	Shared Neighborhood Hits	46
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

CNOT4_HUMAN
NC score	0.079085 (rank : 289)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	436	Target Neighborhood Hits	207	Shared Neighborhood Hits	46
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

RN126_HUMAN
NC score	0.078758 (rank : 290)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	436	Target Neighborhood Hits	126	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN165_HUMAN
NC score	0.078272 (rank : 291)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	436	Target Neighborhood Hits	151	Shared Neighborhood Hits	65
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

MKRN1_MOUSE
NC score	0.078099 (rank : 292)	θ value	4.03905 (rank : 334)
Query Neighborhood Hits	436	Target Neighborhood Hits	141	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QXP6	Gene names	Mkrn1
Domain Architecture
Description	Makorin-1.

CNOT4_MOUSE
NC score	0.077556 (rank : 293)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	436	Target Neighborhood Hits	277	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

BIRC3_HUMAN
NC score	0.077249 (rank : 294)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	436	Target Neighborhood Hits	133	Shared Neighborhood Hits	81
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

MIB2_MOUSE
NC score	0.076830 (rank : 295)	θ value	2.36792 (rank : 292)
Query Neighborhood Hits	436	Target Neighborhood Hits	409	Shared Neighborhood Hits	83
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

ERCC5_MOUSE
NC score	0.076581 (rank : 296)	θ value	0.00102713 (rank : 91)
Query Neighborhood Hits	436	Target Neighborhood Hits	206	Shared Neighborhood Hits	29
SwissProt Accessions	P35689, Q61528, Q64248	Gene names	Ercc5, Ercc-5, Xpg
Domain Architecture
Description	DNA-repair protein complementing XP-G cells homolog (Xeroderma pigmentosum group G-complementing protein homolog) (DNA excision repair protein ERCC-5).

BIRC2_HUMAN
NC score	0.076307 (rank : 297)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	436	Target Neighborhood Hits	142	Shared Neighborhood Hits	88
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

AKA12_HUMAN
NC score	0.075546 (rank : 298)	θ value	1.81305 (rank : 266)
Query Neighborhood Hits	436	Target Neighborhood Hits	825	Shared Neighborhood Hits	97
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

MKRN2_MOUSE
NC score	0.075435 (rank : 299)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	436	Target Neighborhood Hits	130	Shared Neighborhood Hits	67
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

TXND2_MOUSE
NC score	0.075422 (rank : 300)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	436	Target Neighborhood Hits	828	Shared Neighborhood Hits	109
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

RFFL_MOUSE
NC score	0.075092 (rank : 301)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	436	Target Neighborhood Hits	145	Shared Neighborhood Hits	69
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

LRSM1_HUMAN
NC score	0.074670 (rank : 302)	θ value	1.81305 (rank : 271)
Query Neighborhood Hits	436	Target Neighborhood Hits	1078	Shared Neighborhood Hits	127
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

PJA1_MOUSE
NC score	0.074097 (rank : 303)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	436	Target Neighborhood Hits	145	Shared Neighborhood Hits	63
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

ACINU_HUMAN
NC score	0.073489 (rank : 304)	θ value	0.0736092 (rank : 164)
Query Neighborhood Hits	436	Target Neighborhood Hits	828	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

RN103_HUMAN
NC score	0.073393 (rank : 305)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	436	Target Neighborhood Hits	153	Shared Neighborhood Hits	69
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

MKRN2_HUMAN
NC score	0.073298 (rank : 306)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	436	Target Neighborhood Hits	129	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H000, Q8N391, Q96BD4, Q9BUY2, Q9NRY1	Gene names	MKRN2, RNF62
Domain Architecture
Description	Makorin-2 (RING finger protein 62).

RN103_MOUSE
NC score	0.073254 (rank : 307)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	436	Target Neighborhood Hits	143	Shared Neighborhood Hits	66
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

FSD1L_HUMAN
NC score	0.073012 (rank : 308)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	436	Target Neighborhood Hits	57	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BXM9, Q5T880	Gene names	FSD1L, CCDC10, CSDUFD1, FSD1NL
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

BIRC2_MOUSE
NC score	0.072611 (rank : 309)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	436	Target Neighborhood Hits	137	Shared Neighborhood Hits	81
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

LRSM1_MOUSE
NC score	0.071902 (rank : 310)	θ value	0.62314 (rank : 235)
Query Neighborhood Hits	436	Target Neighborhood Hits	874	Shared Neighborhood Hits	108
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

CYLC1_HUMAN
NC score	0.071605 (rank : 311)	θ value	0.125558 (rank : 182)
Query Neighborhood Hits	436	Target Neighborhood Hits	408	Shared Neighborhood Hits	43
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

LEO1_MOUSE
NC score	0.071435 (rank : 312)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	436	Target Neighborhood Hits	946	Shared Neighborhood Hits	104
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

TRAF1_HUMAN
NC score	0.070982 (rank : 313)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	436	Target Neighborhood Hits	65	Shared Neighborhood Hits	16
SwissProt Accessions	Q13077, Q8NF13	Gene names	TRAF1, EBI6
Domain Architecture
Description	TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6).

ATRX_MOUSE
NC score	0.070602 (rank : 314)	θ value	0.47712 (rank : 219)
Query Neighborhood Hits	436	Target Neighborhood Hits	682	Shared Neighborhood Hits	80
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

HIRP3_HUMAN
NC score	0.070495 (rank : 315)	θ value	0.47712 (rank : 222)
Query Neighborhood Hits	436	Target Neighborhood Hits	323	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

TRAF1_MOUSE
NC score	0.070454 (rank : 316)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	436	Target Neighborhood Hits	52	Shared Neighborhood Hits	12
SwissProt Accessions	P39428	Gene names	Traf1
Domain Architecture
Description	TNF receptor-associated factor 1.

TCOF_MOUSE
NC score	0.069411 (rank : 317)	θ value	0.00665767 (rank : 116)
Query Neighborhood Hits	436	Target Neighborhood Hits	471	Shared Neighborhood Hits	30
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TGON2_HUMAN
NC score	0.069377 (rank : 318)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	436	Target Neighborhood Hits	1037	Shared Neighborhood Hits	100
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

SRRM2_MOUSE
NC score	0.067660 (rank : 319)	θ value	0.0113563 (rank : 127)
Query Neighborhood Hits	436	Target Neighborhood Hits	1470	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TARA_HUMAN
NC score	0.067449 (rank : 320)	θ value	1.81305 (rank : 278)
Query Neighborhood Hits	436	Target Neighborhood Hits	1626	Shared Neighborhood Hits	123
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

APC11_HUMAN
NC score	0.067421 (rank : 321)	θ value	1.81305 (rank : 267)
Query Neighborhood Hits	436	Target Neighborhood Hits	74	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NYG5, Q502X9, Q9BW64, Q9P0R2	Gene names	ANAPC11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11) (Hepatocellular carcinoma-associated RING finger protein).

MKRN3_HUMAN
NC score	0.067293 (rank : 322)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	436	Target Neighborhood Hits	165	Shared Neighborhood Hits	69
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

BIRC3_MOUSE
NC score	0.066681 (rank : 323)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	436	Target Neighborhood Hits	113	Shared Neighborhood Hits	71
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

LEO1_HUMAN
NC score	0.066541 (rank : 324)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	436	Target Neighborhood Hits	958	Shared Neighborhood Hits	98
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

RNF24_HUMAN
NC score	0.065823 (rank : 325)	θ value	6.88961 (rank : 398)
Query Neighborhood Hits	436	Target Neighborhood Hits	122	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y225, Q9UMH1	Gene names	RNF24
Domain Architecture
Description	RING finger protein 24.

BSN_HUMAN
NC score	0.064933 (rank : 326)	θ value	0.0563607 (rank : 155)
Query Neighborhood Hits	436	Target Neighborhood Hits	1537	Shared Neighborhood Hits	92
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

ZSWM2_HUMAN
NC score	0.064102 (rank : 327)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	436	Target Neighborhood Hits	151	Shared Neighborhood Hits	45
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

MAP1B_MOUSE
NC score	0.063598 (rank : 328)	θ value	8.99809 (rank : 421)
Query Neighborhood Hits	436	Target Neighborhood Hits	977	Shared Neighborhood Hits	86
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

RSF1_HUMAN
NC score	0.063277 (rank : 329)	θ value	4.03905 (rank : 340)
Query Neighborhood Hits	436	Target Neighborhood Hits	539	Shared Neighborhood Hits	62
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

RNF24_MOUSE
NC score	0.062989 (rank : 330)	θ value	8.99809 (rank : 431)
Query Neighborhood Hits	436	Target Neighborhood Hits	124	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BGI1	Gene names	Rnf24
Domain Architecture	No domain graphic available
Description	RING finger protein 24.

RN122_HUMAN
NC score	0.062681 (rank : 331)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	436	Target Neighborhood Hits	121	Shared Neighborhood Hits	61
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

OSTP_MOUSE
NC score	0.062193 (rank : 332)	θ value	0.365318 (rank : 214)
Query Neighborhood Hits	436	Target Neighborhood Hits	60	Shared Neighborhood Hits	17
SwissProt Accessions	P10923, P19008	Gene names	Spp1, Eta-1, Op, Spp-1
Domain Architecture
Description	Osteopontin precursor (Bone sialoprotein-1) (Secreted phosphoprotein 1) (SPP-1) (Minopontin) (Early T-lymphocyte activation 1 protein) (2AR) (Calcium oxalate crystal growth inhibitor protein).

RNF37_MOUSE
NC score	0.062032 (rank : 333)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	436	Target Neighborhood Hits	102	Shared Neighborhood Hits	55
SwissProt Accessions	Q925F4	Gene names	Ubox5, Rnf37, Ubce7ip5, Uip5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (UbcM4-interacting protein 5) (U-box domain-containing protein 5).

RN167_MOUSE
NC score	0.061148 (rank : 334)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	436	Target Neighborhood Hits	157	Shared Neighborhood Hits	70
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

MPP8_HUMAN
NC score	0.060951 (rank : 335)	θ value	0.0193708 (rank : 135)
Query Neighborhood Hits	436	Target Neighborhood Hits	948	Shared Neighborhood Hits	82
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

SRRM1_MOUSE
NC score	0.060108 (rank : 336)	θ value	0.47712 (rank : 228)
Query Neighborhood Hits	436	Target Neighborhood Hits	966	Shared Neighborhood Hits	63
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

RN122_MOUSE
NC score	0.059451 (rank : 337)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	436	Target Neighborhood Hits	121	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

BSN_MOUSE
NC score	0.059353 (rank : 338)	θ value	0.0330416 (rank : 145)
Query Neighborhood Hits	436	Target Neighborhood Hits	2057	Shared Neighborhood Hits	98
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

PDZK4_MOUSE
NC score	0.059143 (rank : 339)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	436	Target Neighborhood Hits	165	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

RN139_HUMAN
NC score	0.059011 (rank : 340)	θ value	5.27518 (rank : 366)
Query Neighborhood Hits	436	Target Neighborhood Hits	130	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WU17, O75485, Q7LDL3	Gene names	RNF139, TRC8
Domain Architecture	No domain graphic available
Description	RING finger protein 139 (Translocation in renal carcinoma on chromosome 8).

TRI66_MOUSE
NC score	0.058611 (rank : 341)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	436	Target Neighborhood Hits	491	Shared Neighborhood Hits	71
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

SRRM1_HUMAN
NC score	0.058591 (rank : 342)	θ value	0.47712 (rank : 227)
Query Neighborhood Hits	436	Target Neighborhood Hits	690	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM2_HUMAN
NC score	0.058392 (rank : 343)	θ value	5.27518 (rank : 367)
Query Neighborhood Hits	436	Target Neighborhood Hits	1296	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TRI66_HUMAN
NC score	0.057979 (rank : 344)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	436	Target Neighborhood Hits	479	Shared Neighborhood Hits	71
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

AFF1_HUMAN
NC score	0.057817 (rank : 345)	θ value	0.163984 (rank : 189)
Query Neighborhood Hits	436	Target Neighborhood Hits	506	Shared Neighborhood Hits	37
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

JIP2_HUMAN
NC score	0.057656 (rank : 346)	θ value	0.0252991 (rank : 140)
Query Neighborhood Hits	436	Target Neighborhood Hits	288	Shared Neighborhood Hits	12
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

PDZK4_HUMAN
NC score	0.056886 (rank : 347)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	436	Target Neighborhood Hits	165	Shared Neighborhood Hits	12
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

ATRX_HUMAN
NC score	0.056746 (rank : 348)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	436	Target Neighborhood Hits	842	Shared Neighborhood Hits	91
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

RFC1_MOUSE
NC score	0.056731 (rank : 349)	θ value	6.88961 (rank : 397)
Query Neighborhood Hits	436	Target Neighborhood Hits	290	Shared Neighborhood Hits	40
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

RN139_MOUSE
NC score	0.056658 (rank : 350)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	436	Target Neighborhood Hits	131	Shared Neighborhood Hits	58
SwissProt Accessions	Q7TMV1, Q8BZU9	Gene names	Rnf139
Domain Architecture	No domain graphic available
Description	RING finger protein 139.

RN167_HUMAN
NC score	0.056459 (rank : 351)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	436	Target Neighborhood Hits	157	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

DZIP3_MOUSE
NC score	0.056083 (rank : 352)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	436	Target Neighborhood Hits	414	Shared Neighborhood Hits	71
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

CLSPN_HUMAN
NC score	0.055948 (rank : 353)	θ value	0.0736092 (rank : 166)
Query Neighborhood Hits	436	Target Neighborhood Hits	433	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

BPTF_HUMAN
NC score	0.055556 (rank : 354)	θ value	0.279714 (rank : 199)
Query Neighborhood Hits	436	Target Neighborhood Hits	786	Shared Neighborhood Hits	79
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

MYLIP_HUMAN
NC score	0.054975 (rank : 355)	θ value	6.88961 (rank : 390)
Query Neighborhood Hits	436	Target Neighborhood Hits	162	Shared Neighborhood Hits	79
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

PHF14_HUMAN
NC score	0.054261 (rank : 356)	θ value	0.47712 (rank : 224)
Query Neighborhood Hits	436	Target Neighborhood Hits	447	Shared Neighborhood Hits	45
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

JIP2_MOUSE
NC score	0.053979 (rank : 357)	θ value	0.0961366 (rank : 175)
Query Neighborhood Hits	436	Target Neighborhood Hits	144	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

PHF14_MOUSE
NC score	0.053845 (rank : 358)	θ value	1.81305 (rank : 274)
Query Neighborhood Hits	436	Target Neighborhood Hits	342	Shared Neighborhood Hits	48
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

AFF1_MOUSE
NC score	0.052787 (rank : 359)	θ value	1.38821 (rank : 259)
Query Neighborhood Hits	436	Target Neighborhood Hits	351	Shared Neighborhood Hits	33
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

YTDC1_HUMAN
NC score	0.052437 (rank : 360)	θ value	4.03905 (rank : 345)
Query Neighborhood Hits	436	Target Neighborhood Hits	458	Shared Neighborhood Hits	65
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

MDC1_HUMAN
NC score	0.052175 (rank : 361)	θ value	2.36792 (rank : 290)
Query Neighborhood Hits	436	Target Neighborhood Hits	1446	Shared Neighborhood Hits	103
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

ZSWM2_MOUSE
NC score	0.052107 (rank : 362)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	436	Target Neighborhood Hits	132	Shared Neighborhood Hits	47
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

RP1L1_HUMAN
NC score	0.052093 (rank : 363)	θ value	0.813845 (rank : 244)
Query Neighborhood Hits	436	Target Neighborhood Hits	1072	Shared Neighborhood Hits	76
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

MKRN3_MOUSE
NC score	0.051936 (rank : 364)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	436	Target Neighborhood Hits	137	Shared Neighborhood Hits	55
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

RNF13_MOUSE
NC score	0.051717 (rank : 365)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	436	Target Neighborhood Hits	164	Shared Neighborhood Hits	65
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

TTF2_MOUSE
NC score	0.051650 (rank : 366)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	436	Target Neighborhood Hits	364	Shared Neighborhood Hits	52
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

SFRIP_HUMAN
NC score	0.051325 (rank : 367)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	436	Target Neighborhood Hits	530	Shared Neighborhood Hits	64
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

RNF13_HUMAN
NC score	0.050881 (rank : 368)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	436	Target Neighborhood Hits	147	Shared Neighborhood Hits	57
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

DEK_HUMAN
NC score	0.050022 (rank : 369)	θ value	2.36792 (rank : 287)
Query Neighborhood Hits	436	Target Neighborhood Hits	199	Shared Neighborhood Hits	31
SwissProt Accessions	P35659, Q5TGV4, Q5TGV5	Gene names	DEK
Domain Architecture	No domain graphic available
Description	Protein DEK.

GOGB1_HUMAN
NC score	0.049539 (rank : 370)	θ value	6.88961 (rank : 382)
Query Neighborhood Hits	436	Target Neighborhood Hits	2297	Shared Neighborhood Hits	179
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

DNMT1_HUMAN
NC score	0.049280 (rank : 371)	θ value	0.62314 (rank : 233)
Query Neighborhood Hits	436	Target Neighborhood Hits	401	Shared Neighborhood Hits	53
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

HTSF1_HUMAN
NC score	0.048379 (rank : 372)	θ value	0.62314 (rank : 234)
Query Neighborhood Hits	436	Target Neighborhood Hits	408	Shared Neighborhood Hits	35
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

AFF4_HUMAN
NC score	0.048224 (rank : 373)	θ value	8.99809 (rank : 408)
Query Neighborhood Hits	436	Target Neighborhood Hits	611	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

ACINU_MOUSE
NC score	0.048208 (rank : 374)	θ value	8.99809 (rank : 406)
Query Neighborhood Hits	436	Target Neighborhood Hits	712	Shared Neighborhood Hits	59
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

MDC1_MOUSE
NC score	0.047333 (rank : 375)	θ value	2.36792 (rank : 291)
Query Neighborhood Hits	436	Target Neighborhood Hits	998	Shared Neighborhood Hits	74
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

AFF3_HUMAN
NC score	0.047076 (rank : 376)	θ value	1.38821 (rank : 260)
Query Neighborhood Hits	436	Target Neighborhood Hits	190	Shared Neighborhood Hits	32
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

DTX2_MOUSE
NC score	0.046710 (rank : 377)	θ value	3.0926 (rank : 305)
Query Neighborhood Hits	436	Target Neighborhood Hits	76	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R3P2, Q9CZV3, Q9ER07, Q9ER08	Gene names	Dtx2
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (mDTX2).

CHD1_MOUSE
NC score	0.046601 (rank : 378)	θ value	0.0148317 (rank : 130)
Query Neighborhood Hits	436	Target Neighborhood Hits	266	Shared Neighborhood Hits	23
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

DTX2_HUMAN
NC score	0.046390 (rank : 379)	θ value	3.0926 (rank : 304)
Query Neighborhood Hits	436	Target Neighborhood Hits	84	Shared Neighborhood Hits	14
SwissProt Accessions	Q86UW9, Q96H69, Q9H890, Q9P200	Gene names	DTX2, KIAA1528
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (hDTX2).

IF2P_HUMAN
NC score	0.045355 (rank : 380)	θ value	0.813845 (rank : 241)
Query Neighborhood Hits	436	Target Neighborhood Hits	889	Shared Neighborhood Hits	66
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

EP15_HUMAN
NC score	0.045127 (rank : 381)	θ value	1.06291 (rank : 251)
Query Neighborhood Hits	436	Target Neighborhood Hits	1021	Shared Neighborhood Hits	66
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

SFRS4_MOUSE
NC score	0.044942 (rank : 382)	θ value	0.0961366 (rank : 176)
Query Neighborhood Hits	436	Target Neighborhood Hits	406	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

APC_HUMAN
NC score	0.044388 (rank : 383)	θ value	0.365318 (rank : 209)
Query Neighborhood Hits	436	Target Neighborhood Hits	603	Shared Neighborhood Hits	59
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

TMCC1_MOUSE
NC score	0.043442 (rank : 384)	θ value	0.0961366 (rank : 177)
Query Neighborhood Hits	436	Target Neighborhood Hits	315	Shared Neighborhood Hits	27
SwissProt Accessions	Q69ZZ6, Q8CEF4	Gene names	Tmcc1, Kiaa0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

CHD1_HUMAN
NC score	0.043302 (rank : 385)	θ value	1.06291 (rank : 247)
Query Neighborhood Hits	436	Target Neighborhood Hits	337	Shared Neighborhood Hits	35
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

K0408_HUMAN
NC score	0.043217 (rank : 386)	θ value	1.06291 (rank : 254)
Query Neighborhood Hits	436	Target Neighborhood Hits	101	Shared Neighborhood Hits	16
SwissProt Accessions	Q6ZU52, O43158, Q5TF20, Q7L2M2	Gene names	KIAA0408
Domain Architecture	No domain graphic available
Description	Protein KIAA0408.

BICD2_HUMAN
NC score	0.043147 (rank : 387)	θ value	0.125558 (rank : 180)
Query Neighborhood Hits	436	Target Neighborhood Hits	856	Shared Neighborhood Hits	63
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BICD2_MOUSE
NC score	0.043098 (rank : 388)	θ value	0.125558 (rank : 181)
Query Neighborhood Hits	436	Target Neighborhood Hits	864	Shared Neighborhood Hits	65
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

CJ006_MOUSE
NC score	0.043076 (rank : 389)	θ value	0.21417 (rank : 192)
Query Neighborhood Hits	436	Target Neighborhood Hits	141	Shared Neighborhood Hits	18
SwissProt Accessions	Q6P9P0, Q8C041, Q8C0J5	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf6 homolog.

TMCC1_HUMAN
NC score	0.042868 (rank : 390)	θ value	0.125558 (rank : 185)
Query Neighborhood Hits	436	Target Neighborhood Hits	337	Shared Neighborhood Hits	28
SwissProt Accessions	O94876, Q68E06, Q8IXM8	Gene names	TMCC1, KIAA0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

PSIP1_HUMAN
NC score	0.042824 (rank : 391)	θ value	0.62314 (rank : 236)
Query Neighborhood Hits	436	Target Neighborhood Hits	341	Shared Neighborhood Hits	35
SwissProt Accessions	O75475, O00256, O95368, Q6P391, Q86YB9, Q9NZI3, Q9UER6	Gene names	PSIP1, DFS70, LEDGF, PSIP2
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52) (Dense fine speckles 70 kDa protein) (DFS 70) (CLL-associated antigen KW-7).

PHF20_MOUSE
NC score	0.042328 (rank : 392)	θ value	3.0926 (rank : 317)
Query Neighborhood Hits	436	Target Neighborhood Hits	513	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

CENPF_HUMAN
NC score	0.042293 (rank : 393)	θ value	5.27518 (rank : 352)
Query Neighborhood Hits	436	Target Neighborhood Hits	1932	Shared Neighborhood Hits	143
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

EP15_MOUSE
NC score	0.041866 (rank : 394)	θ value	2.36792 (rank : 289)
Query Neighborhood Hits	436	Target Neighborhood Hits	820	Shared Neighborhood Hits	49
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

PCX1_HUMAN
NC score	0.040697 (rank : 395)	θ value	0.47712 (rank : 223)
Query Neighborhood Hits	436	Target Neighborhood Hits	102	Shared Neighborhood Hits	14
SwissProt Accessions	Q96RV3, O94897, Q96AI7, Q9Y2J9	Gene names	PCNX, KIAA0805, KIAA0995, PCNXL1
Domain Architecture
Description	Pecanex-like protein 1 (Pecanex homolog).

CP250_MOUSE
NC score	0.040498 (rank : 396)	θ value	0.0563607 (rank : 156)
Query Neighborhood Hits	436	Target Neighborhood Hits	1583	Shared Neighborhood Hits	109
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

ATX3_HUMAN
NC score	0.039967 (rank : 397)	θ value	0.62314 (rank : 231)
Query Neighborhood Hits	436	Target Neighborhood Hits	117	Shared Neighborhood Hits	9
SwissProt Accessions	P54252, O15284, O15285, O15286, Q8N189, Q96TC3, Q96TC4, Q9H3N0	Gene names	ATXN3, ATX3, MJD, MJD1, SCA3
Domain Architecture
Description	Ataxin-3 (EC 3.4.22.-) (Machado-Joseph disease protein 1) (Spinocerebellar ataxia type 3 protein).

TARA_MOUSE
NC score	0.039601 (rank : 398)	θ value	8.99809 (rank : 434)
Query Neighborhood Hits	436	Target Neighborhood Hits	1133	Shared Neighborhood Hits	80
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

MYRIP_HUMAN
NC score	0.039106 (rank : 399)	θ value	0.365318 (rank : 213)
Query Neighborhood Hits	436	Target Neighborhood Hits	269	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

PCLO_HUMAN
NC score	0.038932 (rank : 400)	θ value	8.99809 (rank : 426)
Query Neighborhood Hits	436	Target Neighborhood Hits	2046	Shared Neighborhood Hits	122
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

HUWE1_HUMAN
NC score	0.036611 (rank : 401)	θ value	0.0736092 (rank : 167)
Query Neighborhood Hits	436	Target Neighborhood Hits	443	Shared Neighborhood Hits	31
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HMMR_HUMAN
NC score	0.036439 (rank : 402)	θ value	0.125558 (rank : 183)
Query Neighborhood Hits	436	Target Neighborhood Hits	1082	Shared Neighborhood Hits	74
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

SPRL1_MOUSE
NC score	0.036223 (rank : 403)	θ value	6.88961 (rank : 400)
Query Neighborhood Hits	436	Target Neighborhood Hits	403	Shared Neighborhood Hits	56
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

RAD17_HUMAN
NC score	0.035856 (rank : 404)	θ value	0.47712 (rank : 225)
Query Neighborhood Hits	436	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	O75943, O75714, Q7Z3S4, Q9UNK7, Q9UNR7, Q9UNR8, Q9UPF5	Gene names	RAD17, R24L
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint protein RAD17 (hRad17) (RF-C/activator 1 homolog).

UBF1_HUMAN
NC score	0.035853 (rank : 405)	θ value	0.365318 (rank : 216)
Query Neighborhood Hits	436	Target Neighborhood Hits	415	Shared Neighborhood Hits	29
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

UBP53_MOUSE
NC score	0.035834 (rank : 406)	θ value	0.365318 (rank : 217)
Query Neighborhood Hits	436	Target Neighborhood Hits	188	Shared Neighborhood Hits	23
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

CE290_HUMAN
NC score	0.034993 (rank : 407)	θ value	8.99809 (rank : 411)
Query Neighborhood Hits	436	Target Neighborhood Hits	1553	Shared Neighborhood Hits	124
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CENPE_HUMAN
NC score	0.034821 (rank : 408)	θ value	8.99809 (rank : 412)
Query Neighborhood Hits	436	Target Neighborhood Hits	2060	Shared Neighborhood Hits	150
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

BAZ2B_HUMAN
NC score	0.034784 (rank : 409)	θ value	5.27518 (rank : 351)
Query Neighborhood Hits	436	Target Neighborhood Hits	803	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

HUWE1_MOUSE
NC score	0.034475 (rank : 410)	θ value	0.0736092 (rank : 168)
Query Neighborhood Hits	436	Target Neighborhood Hits	406	Shared Neighborhood Hits	27
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

CHD8_HUMAN
NC score	0.033925 (rank : 411)	θ value	0.813845 (rank : 239)
Query Neighborhood Hits	436	Target Neighborhood Hits	235	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

DAXX_MOUSE
NC score	0.033820 (rank : 412)	θ value	3.0926 (rank : 303)
Query Neighborhood Hits	436	Target Neighborhood Hits	173	Shared Neighborhood Hits	21
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

NFH_HUMAN
NC score	0.033779 (rank : 413)	θ value	0.0113563 (rank : 124)
Query Neighborhood Hits	436	Target Neighborhood Hits	1242	Shared Neighborhood Hits	85
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RABE2_MOUSE
NC score	0.033198 (rank : 414)	θ value	0.813845 (rank : 243)
Query Neighborhood Hits	436	Target Neighborhood Hits	598	Shared Neighborhood Hits	47
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

OPTN_MOUSE
NC score	0.032897 (rank : 415)	θ value	8.99809 (rank : 425)
Query Neighborhood Hits	436	Target Neighborhood Hits	1120	Shared Neighborhood Hits	78
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

PPIG_HUMAN
NC score	0.032838 (rank : 416)	θ value	1.81305 (rank : 276)
Query Neighborhood Hits	436	Target Neighborhood Hits	670	Shared Neighborhood Hits	70
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

K1210_HUMAN
NC score	0.032744 (rank : 417)	θ value	5.27518 (rank : 360)
Query Neighborhood Hits	436	Target Neighborhood Hits	219	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

MYST3_HUMAN
NC score	0.032060 (rank : 418)	θ value	3.0926 (rank : 312)
Query Neighborhood Hits	436	Target Neighborhood Hits	772	Shared Neighborhood Hits	63
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

BRWD1_MOUSE
NC score	0.031947 (rank : 419)	θ value	0.0148317 (rank : 129)
Query Neighborhood Hits	436	Target Neighborhood Hits	478	Shared Neighborhood Hits	34
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

AF9_HUMAN
NC score	0.031598 (rank : 420)	θ value	8.99809 (rank : 407)
Query Neighborhood Hits	436	Target Neighborhood Hits	202	Shared Neighborhood Hits	20
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

ABTAP_MOUSE
NC score	0.030424 (rank : 421)	θ value	8.99809 (rank : 405)
Query Neighborhood Hits	436	Target Neighborhood Hits	381	Shared Neighborhood Hits	37
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

TOIP2_HUMAN
NC score	0.030287 (rank : 422)	θ value	5.27518 (rank : 370)
Query Neighborhood Hits	436	Target Neighborhood Hits	102	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NFQ8	Gene names	TOR1AIP2, LULL1
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2 (Lumenal domain-like LAP1).

PO121_HUMAN
NC score	0.030008 (rank : 423)	θ value	1.81305 (rank : 275)
Query Neighborhood Hits	436	Target Neighborhood Hits	344	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

HIP1_HUMAN
NC score	0.029968 (rank : 424)	θ value	0.365318 (rank : 212)
Query Neighborhood Hits	436	Target Neighborhood Hits	1016	Shared Neighborhood Hits	68
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

RFIP1_HUMAN
NC score	0.029356 (rank : 425)	θ value	1.06291 (rank : 256)
Query Neighborhood Hits	436	Target Neighborhood Hits	236	Shared Neighborhood Hits	17
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

SRCA_HUMAN
NC score	0.029162 (rank : 426)	θ value	1.81305 (rank : 277)
Query Neighborhood Hits	436	Target Neighborhood Hits	380	Shared Neighborhood Hits	36
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

CF096_HUMAN
NC score	0.028786 (rank : 427)	θ value	1.06291 (rank : 246)
Query Neighborhood Hits	436	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NWS8, Q5SZ48, Q5SZ83, Q6NSC5, Q96EN7	Gene names	C6orf96
Domain Architecture	No domain graphic available
Description	Protein C6orf96.

PHF3_HUMAN
NC score	0.028643 (rank : 428)	θ value	3.0926 (rank : 318)
Query Neighborhood Hits	436	Target Neighborhood Hits	419	Shared Neighborhood Hits	31
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

EEA1_MOUSE
NC score	0.028008 (rank : 429)	θ value	5.27518 (rank : 355)
Query Neighborhood Hits	436	Target Neighborhood Hits	1637	Shared Neighborhood Hits	110
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

ASIP_MOUSE
NC score	0.027903 (rank : 430)	θ value	5.27518 (rank : 349)
Query Neighborhood Hits	436	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q03288, Q80ST0	Gene names	Asip, a
Domain Architecture
Description	Agouti signaling protein precursor (ASP) (Agouti switch protein) (Agouti coat color protein).

GASP1_MOUSE
NC score	0.027383 (rank : 431)	θ value	1.06291 (rank : 252)
Query Neighborhood Hits	436	Target Neighborhood Hits	169	Shared Neighborhood Hits	28
SwissProt Accessions	Q5U4C1, Q8BKR8, Q8BUN4, Q8BYK9, Q8CHF4, Q8R095	Gene names	Gprasp1, Kiaa0443
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 1 (GASP-1).

ATX3_MOUSE
NC score	0.027356 (rank : 432)	θ value	5.27518 (rank : 350)
Query Neighborhood Hits	436	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CVD2	Gene names	Atxn3, Mjd
Domain Architecture
Description	Ataxin-3 (EC 3.4.22.-) (Machado-Joseph disease protein 1 homolog).

HEMGN_HUMAN
NC score	0.027230 (rank : 433)	θ value	4.03905 (rank : 332)
Query Neighborhood Hits	436	Target Neighborhood Hits	92	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BXL5, Q6XAR3, Q86XY5, Q9NPC0	Gene names	HEMGN, EDAG, NDR
Domain Architecture	No domain graphic available
Description	Hemogen (Hemopoietic gene protein) (Negative differentiation regulator protein) (Erythroid differentiation-associated gene protein) (EDAG-1).

RBM25_HUMAN
NC score	0.027163 (rank : 434)	θ value	4.03905 (rank : 339)
Query Neighborhood Hits	436	Target Neighborhood Hits	682	Shared Neighborhood Hits	49
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

ICAL_MOUSE
NC score	0.026659 (rank : 435)	θ value	8.99809 (rank : 419)
Query Neighborhood Hits	436	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	P51125, Q9EQV4, Q9EQV5, Q9QXQ3, Q9QXQ4, Q9R0N1	Gene names	Cast
Domain Architecture
Description	Calpastatin (Calpain inhibitor).

CAC1H_MOUSE
NC score	0.025743 (rank : 436)	θ value	0.0252991 (rank : 139)
Query Neighborhood Hits	436	Target Neighborhood Hits	230	Shared Neighborhood Hits	16
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

TOIP1_HUMAN
NC score	0.025627 (rank : 437)	θ value	4.03905 (rank : 344)
Query Neighborhood Hits	436	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q5JTV8, Q5JTV6, Q8IZ65, Q9H8Y6, Q9HAJ1, Q9NV52, Q9Y3X5	Gene names	TOR1AIP1
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 1.

MYH11_MOUSE
NC score	0.025469 (rank : 438)	θ value	5.27518 (rank : 362)
Query Neighborhood Hits	436	Target Neighborhood Hits	1777	Shared Neighborhood Hits	132
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

TCP10_HUMAN
NC score	0.025382 (rank : 439)	θ value	5.27518 (rank : 369)
Query Neighborhood Hits	436	Target Neighborhood Hits	134	Shared Neighborhood Hits	18
SwissProt Accessions	Q12799	Gene names	TCP10, TCP10A
Domain Architecture
Description	T-complex protein 10A homolog.

K0460_HUMAN
NC score	0.025108 (rank : 440)	θ value	3.0926 (rank : 310)
Query Neighborhood Hits	436	Target Neighborhood Hits	357	Shared Neighborhood Hits	37
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

AKAP6_HUMAN
NC score	0.024906 (rank : 441)	θ value	5.27518 (rank : 347)
Query Neighborhood Hits	436	Target Neighborhood Hits	263	Shared Neighborhood Hits	37
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

CDN1C_MOUSE
NC score	0.024812 (rank : 442)	θ value	4.03905 (rank : 327)
Query Neighborhood Hits	436	Target Neighborhood Hits	161	Shared Neighborhood Hits	16
SwissProt Accessions	P49919	Gene names	Cdkn1c, Kip2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

EMAL4_HUMAN
NC score	0.024554 (rank : 443)	θ value	1.06291 (rank : 250)
Query Neighborhood Hits	436	Target Neighborhood Hits	306	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HC35	Gene names	EML4, C2orf2, EMAPL4
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 4 (EMAP-4) (Restrictedly overexpressed proliferation-associated protein) (Ropp 120).

CKAP2_HUMAN
NC score	0.024191 (rank : 444)	θ value	4.03905 (rank : 328)
Query Neighborhood Hits	436	Target Neighborhood Hits	116	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WWK9, Q3KRA5, Q5VXB4, Q8IWV5, Q8IWV6, Q96FH9, Q9H012, Q9H0D0, Q9H988, Q9HC49, Q9NVG4	Gene names	CKAP2, LB1, TMAP
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 2 (Tumor-associated microtubule- associated protein) (CTCL tumor antigen se20-10).

TM131_MOUSE
NC score	0.023798 (rank : 445)	θ value	6.88961 (rank : 402)
Query Neighborhood Hits	436	Target Neighborhood Hits	156	Shared Neighborhood Hits	18
SwissProt Accessions	O70472	Gene names	Tmem131, D1Bwg0491e, Rw1
Domain Architecture	No domain graphic available
Description	Transmembrane protein 131 (Protein RW1).

SYNP2_MOUSE
NC score	0.023651 (rank : 446)	θ value	0.47712 (rank : 229)
Query Neighborhood Hits	436	Target Neighborhood Hits	252	Shared Neighborhood Hits	16
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

IASPP_HUMAN
NC score	0.023300 (rank : 447)	θ value	1.06291 (rank : 253)
Query Neighborhood Hits	436	Target Neighborhood Hits	688	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

RERE_HUMAN
NC score	0.023287 (rank : 448)	θ value	2.36792 (rank : 297)
Query Neighborhood Hits	436	Target Neighborhood Hits	779	Shared Neighborhood Hits	36
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

AMPH_MOUSE
NC score	0.023078 (rank : 449)	θ value	1.38821 (rank : 261)
Query Neighborhood Hits	436	Target Neighborhood Hits	291	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

NOL10_HUMAN
NC score	0.022776 (rank : 450)	θ value	4.03905 (rank : 336)
Query Neighborhood Hits	436	Target Neighborhood Hits	254	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BSC4, Q53RC9, Q96TA5, Q9H7Y7, Q9H855	Gene names	NOL10
Domain Architecture	No domain graphic available
Description	Nucleolar protein 10.

NOP56_MOUSE
NC score	0.022636 (rank : 451)	θ value	4.03905 (rank : 337)
Query Neighborhood Hits	436	Target Neighborhood Hits	129	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D6Z1, Q3UD45, Q8BVL1, Q8VDT2, Q99LT8, Q9CT15	Gene names	Nol5a, Nop56
Domain Architecture
Description	Nucleolar protein Nop56 (Nucleolar protein 5A).

AP3B1_HUMAN
NC score	0.022581 (rank : 452)	θ value	5.27518 (rank : 348)
Query Neighborhood Hits	436	Target Neighborhood Hits	283	Shared Neighborhood Hits	37
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

KCNA4_HUMAN
NC score	0.022296 (rank : 453)	θ value	0.0148317 (rank : 131)
Query Neighborhood Hits	436	Target Neighborhood Hits	108	Shared Neighborhood Hits	5
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

RERE_MOUSE
NC score	0.022195 (rank : 454)	θ value	8.99809 (rank : 429)
Query Neighborhood Hits	436	Target Neighborhood Hits	785	Shared Neighborhood Hits	44
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

MPP10_MOUSE
NC score	0.022112 (rank : 455)	θ value	3.0926 (rank : 311)
Query Neighborhood Hits	436	Target Neighborhood Hits	251	Shared Neighborhood Hits	20
SwissProt Accessions	Q810V0	Gene names	Mphosph10
Domain Architecture	No domain graphic available
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

ARI1B_HUMAN
NC score	0.022072 (rank : 456)	θ value	4.03905 (rank : 325)
Query Neighborhood Hits	436	Target Neighborhood Hits	567	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

GP73_HUMAN
NC score	0.021657 (rank : 457)	θ value	6.88961 (rank : 383)
Query Neighborhood Hits	436	Target Neighborhood Hits	309	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NBJ4, Q6IAF4, Q9NRB9	Gene names	GOLPH2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

FYCO1_MOUSE
NC score	0.021570 (rank : 458)	θ value	3.0926 (rank : 307)
Query Neighborhood Hits	436	Target Neighborhood Hits	1059	Shared Neighborhood Hits	61
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

TBC12_HUMAN
NC score	0.021507 (rank : 459)	θ value	2.36792 (rank : 299)
Query Neighborhood Hits	436	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	O60347, Q5VYA6, Q8WX26, Q8WX59, Q9UG83	Gene names	TBC1D12, KIAA0608
Domain Architecture
Description	TBC1 domain family member 12.

TBC14_HUMAN
NC score	0.021218 (rank : 460)	θ value	1.81305 (rank : 279)
Query Neighborhood Hits	436	Target Neighborhood Hits	124	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P2M4, Q8IW15	Gene names	TBC1D14, KIAA1322
Domain Architecture
Description	TBC1 domain family member 14.

SYTL5_HUMAN
NC score	0.021122 (rank : 461)	θ value	0.365318 (rank : 215)
Query Neighborhood Hits	436	Target Neighborhood Hits	237	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

MMTA2_MOUSE
NC score	0.020681 (rank : 462)	θ value	8.99809 (rank : 423)
Query Neighborhood Hits	436	Target Neighborhood Hits	40	Shared Neighborhood Hits	8
SwissProt Accessions	Q99LX5, Q9CSK6	Gene names	Mmtag2
Domain Architecture	No domain graphic available
Description	Multiple myeloma tumor-associated protein 2 homolog.

MYT1_HUMAN
NC score	0.020582 (rank : 463)	θ value	2.36792 (rank : 293)
Query Neighborhood Hits	436	Target Neighborhood Hits	475	Shared Neighborhood Hits	41
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

MYH4_HUMAN
NC score	0.020449 (rank : 464)	θ value	1.38821 (rank : 265)
Query Neighborhood Hits	436	Target Neighborhood Hits	1377	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

CD19_MOUSE
NC score	0.020367 (rank : 465)	θ value	3.0926 (rank : 302)
Query Neighborhood Hits	436	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	P25918	Gene names	Cd19
Domain Architecture
Description	B-lymphocyte antigen CD19 precursor (Differentiation antigen CD19).

CENPT_MOUSE
NC score	0.020237 (rank : 466)	θ value	5.27518 (rank : 353)
Query Neighborhood Hits	436	Target Neighborhood Hits	115	Shared Neighborhood Hits	10
SwissProt Accessions	Q3TJM4, Q3TPY6, Q3UPD2, Q8BTH0, Q8BTP2, Q8R5E9	Gene names	Cenpt
Domain Architecture	No domain graphic available
Description	Centromere protein T (CENP-T).

RUFY2_MOUSE
NC score	0.019232 (rank : 467)	θ value	6.88961 (rank : 399)
Query Neighborhood Hits	436	Target Neighborhood Hits	820	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

NOP56_HUMAN
NC score	0.019196 (rank : 468)	θ value	8.99809 (rank : 424)
Query Neighborhood Hits	436	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	O00567, Q9NQ05	Gene names	NOL5A, NOP56
Domain Architecture
Description	Nucleolar protein Nop56 (Nucleolar protein 5A).

IF4G3_HUMAN
NC score	0.019116 (rank : 469)	θ value	1.38821 (rank : 263)
Query Neighborhood Hits	436	Target Neighborhood Hits	247	Shared Neighborhood Hits	22
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

PIAS3_MOUSE
NC score	0.019082 (rank : 470)	θ value	0.813845 (rank : 242)
Query Neighborhood Hits	436	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	O54714, Q80WF8, Q8R598	Gene names	Pias3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

KCNA4_MOUSE
NC score	0.018870 (rank : 471)	θ value	0.163984 (rank : 190)
Query Neighborhood Hits	436	Target Neighborhood Hits	98	Shared Neighborhood Hits	3
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

CCNB3_MOUSE
NC score	0.018469 (rank : 472)	θ value	1.81305 (rank : 268)
Query Neighborhood Hits	436	Target Neighborhood Hits	211	Shared Neighborhood Hits	21
SwissProt Accessions	Q810T2, Q810T3, Q8VDC8	Gene names	Ccnb3, Cycb3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

CAC1S_MOUSE
NC score	0.018439 (rank : 473)	θ value	0.0736092 (rank : 165)
Query Neighborhood Hits	436	Target Neighborhood Hits	98	Shared Neighborhood Hits	5
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

ANK1_MOUSE
NC score	0.018398 (rank : 474)	θ value	6.88961 (rank : 375)
Query Neighborhood Hits	436	Target Neighborhood Hits	430	Shared Neighborhood Hits	27
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

GABP2_HUMAN
NC score	0.018382 (rank : 475)	θ value	6.88961 (rank : 381)
Query Neighborhood Hits	436	Target Neighborhood Hits	454	Shared Neighborhood Hits	19
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

NEDD1_MOUSE
NC score	0.018046 (rank : 476)	θ value	3.0926 (rank : 313)
Query Neighborhood Hits	436	Target Neighborhood Hits	281	Shared Neighborhood Hits	17
SwissProt Accessions	P33215, Q6NXV3, Q8BN12, Q8BN86, Q8BQL9, Q9CWK2	Gene names	Nedd1, Nedd-1
Domain Architecture	No domain graphic available
Description	Protein NEDD1 (Neural precursor cell expressed developmentally down- regulated protein 1).

GP149_HUMAN
NC score	0.017692 (rank : 477)	θ value	3.0926 (rank : 308)
Query Neighborhood Hits	436	Target Neighborhood Hits	68	Shared Neighborhood Hits	4
SwissProt Accessions	Q86SP6	Gene names	GPR149, PGR10
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 149 (G-protein coupled receptor PGR10).

PP4R1_HUMAN
NC score	0.017338 (rank : 478)	θ value	2.36792 (rank : 295)
Query Neighborhood Hits	436	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TF05, Q99774, Q9UNQ7	Gene names	PPP4R1, MEG1, PP4R1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

PRGR_HUMAN
NC score	0.017176 (rank : 479)	θ value	0.0330416 (rank : 149)
Query Neighborhood Hits	436	Target Neighborhood Hits	163	Shared Neighborhood Hits	6
SwissProt Accessions	P06401, Q9UPF7	Gene names	PGR, NR3C3
Domain Architecture
Description	Progesterone receptor (PR).

K0431_HUMAN
NC score	0.016771 (rank : 480)	θ value	6.88961 (rank : 386)
Query Neighborhood Hits	436	Target Neighborhood Hits	211	Shared Neighborhood Hits	7
SwissProt Accessions	O43313	Gene names	KIAA0431
Domain Architecture	No domain graphic available
Description	Protein KIAA0431.

MDFI_MOUSE
NC score	0.016490 (rank : 481)	θ value	6.88961 (rank : 389)
Query Neighborhood Hits	436	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	P70331, P70330, P70332, Q99JM9	Gene names	Mdfi
Domain Architecture	No domain graphic available
Description	MyoD family inhibitor (Myogenic repressor I-mf).

E2F5_MOUSE
NC score	0.016067 (rank : 482)	θ value	1.81305 (rank : 270)
Query Neighborhood Hits	436	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q61502	Gene names	E2f5
Domain Architecture
Description	Transcription factor E2F5 (E2F-5).

CDA7L_HUMAN
NC score	0.016017 (rank : 483)	θ value	8.99809 (rank : 410)
Query Neighborhood Hits	436	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	Q96GN5, Q6PIL4, Q86YT0, Q8IXN5, Q96C70, Q9H9A2, Q9NPV2	Gene names	CDCA7L, HR1, JPO2, R1
Domain Architecture	No domain graphic available
Description	Cell division cycle-associated 7-like protein (Protein JPO2) (Transcription factor RAM2).

ZN198_HUMAN
NC score	0.015983 (rank : 484)	θ value	4.03905 (rank : 346)
Query Neighborhood Hits	436	Target Neighborhood Hits	128	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UBW7, O43212, O43434, O60898, Q5W0Q4, Q63HP0, Q8NE39, Q9H538, Q9UEU2	Gene names	ZNF198, FIM, RAMP, ZMYM2
Domain Architecture
Description	Zinc finger protein 198 (Zinc finger MYM-type protein 2) (Fused in myeloproliferative disorders protein) (Rearranged in atypical myeloproliferative disorder protein).

EF2K_HUMAN
NC score	0.015712 (rank : 485)	θ value	5.27518 (rank : 356)
Query Neighborhood Hits	436	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	O00418	Gene names	EEF2K
Domain Architecture
Description	Elongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase).

UBP31_HUMAN
NC score	0.015667 (rank : 486)	θ value	5.27518 (rank : 373)
Query Neighborhood Hits	436	Target Neighborhood Hits	293	Shared Neighborhood Hits	30
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

HORN_MOUSE
NC score	0.015508 (rank : 487)	θ value	8.99809 (rank : 418)
Query Neighborhood Hits	436	Target Neighborhood Hits	218	Shared Neighborhood Hits	16
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

TTLL5_HUMAN
NC score	0.015336 (rank : 488)	θ value	2.36792 (rank : 301)
Query Neighborhood Hits	436	Target Neighborhood Hits	141	Shared Neighborhood Hits	16
SwissProt Accessions	Q6EMB2, Q9P1V5, Q9UPZ4	Gene names	TTLL5, KIAA0998, STAMP
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5 (SRC1 and TIF2-associated modulatory protein).

PP2CG_HUMAN
NC score	0.015080 (rank : 489)	θ value	5.27518 (rank : 365)
Query Neighborhood Hits	436	Target Neighborhood Hits	140	Shared Neighborhood Hits	13
SwissProt Accessions	O15355	Gene names	PPM1G, PPM1C
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C).

PIAS3_HUMAN
NC score	0.014991 (rank : 490)	θ value	4.03905 (rank : 338)
Query Neighborhood Hits	436	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6X2, Q9UFI3	Gene names	PIAS3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

IF39_HUMAN
NC score	0.014874 (rank : 491)	θ value	6.88961 (rank : 385)
Query Neighborhood Hits	436	Target Neighborhood Hits	187	Shared Neighborhood Hits	14
SwissProt Accessions	P55884, Q9UMF9	Gene names	EIF3S9
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) (Prt1 homolog) (hPrt1).

DHX36_HUMAN
NC score	0.014599 (rank : 492)	θ value	0.813845 (rank : 240)
Query Neighborhood Hits	436	Target Neighborhood Hits	63	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H2U1, Q70JU3, Q8IYE5, Q9P240	Gene names	DHX36, DDX36, KIAA1488, MLEL1, RHAU
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

NFAT5_HUMAN
NC score	0.014179 (rank : 493)	θ value	4.03905 (rank : 335)
Query Neighborhood Hits	436	Target Neighborhood Hits	217	Shared Neighborhood Hits	9
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

PRP4B_MOUSE
NC score	0.014075 (rank : 494)	θ value	0.0736092 (rank : 170)
Query Neighborhood Hits	436	Target Neighborhood Hits	1040	Shared Neighborhood Hits	49
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

KI21A_MOUSE
NC score	0.013278 (rank : 495)	θ value	6.88961 (rank : 387)
Query Neighborhood Hits	436	Target Neighborhood Hits	1317	Shared Neighborhood Hits	86
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

DNL3_MOUSE
NC score	0.013205 (rank : 496)	θ value	4.03905 (rank : 330)
Query Neighborhood Hits	436	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	P97386, P97385	Gene names	Lig3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

K0226_HUMAN
NC score	0.013202 (rank : 497)	θ value	5.27518 (rank : 359)
Query Neighborhood Hits	436	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	Q92622	Gene names	KIAA0226
Domain Architecture	No domain graphic available
Description	Protein KIAA0226.

NFAT5_MOUSE
NC score	0.012815 (rank : 498)	θ value	6.88961 (rank : 393)
Query Neighborhood Hits	436	Target Neighborhood Hits	162	Shared Neighborhood Hits	11
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

H13_MOUSE
NC score	0.012619 (rank : 499)	θ value	4.03905 (rank : 331)
Query Neighborhood Hits	436	Target Neighborhood Hits	81	Shared Neighborhood Hits	9
SwissProt Accessions	P43277, Q8C6M4	Gene names	Hist1h1d, H1f3
Domain Architecture
Description	Histone H1.3 (H1 VAR.4) (H1d).

DMRTC_MOUSE
NC score	0.012508 (rank : 500)	θ value	8.99809 (rank : 414)
Query Neighborhood Hits	436	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D9R7, Q2PMY0, Q9D5U3	Gene names	Dmrtc1, Dmrt8.1
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C1 (Doublesex- and mab-3-related transcription factor 8.1).

CJ078_HUMAN
NC score	0.012491 (rank : 501)	θ value	8.99809 (rank : 413)
Query Neighborhood Hits	436	Target Neighborhood Hits	61	Shared Neighborhood Hits	8
SwissProt Accessions	Q86XK3, Q5JT40, Q8WW47	Gene names	C10orf78
Domain Architecture	No domain graphic available
Description	Protein C10orf78.

DHX36_MOUSE
NC score	0.012456 (rank : 502)	θ value	2.36792 (rank : 288)
Query Neighborhood Hits	436	Target Neighborhood Hits	114	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

IYD1_HUMAN
NC score	0.011104 (rank : 503)	θ value	8.99809 (rank : 420)
Query Neighborhood Hits	436	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PHW0, Q2VPW0, Q2VPW1, Q5F1L5, Q5F1L6, Q5THM4, Q6ZP69, Q7Z7D7, Q7Z7D8	Gene names	IYD, C6orf71, DEHAL1
Domain Architecture	No domain graphic available
Description	Iodotyrosine dehalogenase 1 precursor (EC 1.-.-.-) (IYD-1).

PRP4B_HUMAN
NC score	0.010998 (rank : 504)	θ value	2.36792 (rank : 296)
Query Neighborhood Hits	436	Target Neighborhood Hits	1030	Shared Neighborhood Hits	54
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

TIAM1_HUMAN
NC score	0.010805 (rank : 505)	θ value	4.03905 (rank : 343)
Query Neighborhood Hits	436	Target Neighborhood Hits	225	Shared Neighborhood Hits	12
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

G3BP_HUMAN
NC score	0.010559 (rank : 506)	θ value	6.88961 (rank : 380)
Query Neighborhood Hits	436	Target Neighborhood Hits	219	Shared Neighborhood Hits	13
SwissProt Accessions	Q13283	Gene names	G3BP, G3BP1
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 1 (EC 3.6.1.-) (ATP- dependent DNA helicase VIII) (GAP SH3-domain-binding protein 1) (G3BP- 1) (HDH-VIII).

NPAS2_HUMAN
NC score	0.010432 (rank : 507)	θ value	1.81305 (rank : 273)
Query Neighborhood Hits	436	Target Neighborhood Hits	150	Shared Neighborhood Hits	8
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

HOMEZ_HUMAN
NC score	0.010319 (rank : 508)	θ value	8.99809 (rank : 417)
Query Neighborhood Hits	436	Target Neighborhood Hits	110	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IX15, Q6P049, Q86XB6, Q9P2A5	Gene names	HOMEZ, KIAA1443
Domain Architecture
Description	Homeobox and leucine zipper protein Homez (Homeodomain leucine zipper- containing factor).

H13_HUMAN
NC score	0.010127 (rank : 509)	θ value	6.88961 (rank : 384)
Query Neighborhood Hits	436	Target Neighborhood Hits	61	Shared Neighborhood Hits	7
SwissProt Accessions	P16402	Gene names	HIST1H1D, H1F3
Domain Architecture
Description	Histone H1.3 (Histone H1c).

LIX1_HUMAN
NC score	0.010084 (rank : 510)	θ value	6.88961 (rank : 388)
Query Neighborhood Hits	436	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N485, Q8N7I2	Gene names	LIX1
Domain Architecture	No domain graphic available
Description	Protein limb expression 1 homolog.

E41L2_HUMAN
NC score	0.009096 (rank : 511)	θ value	6.88961 (rank : 379)
Query Neighborhood Hits	436	Target Neighborhood Hits	287	Shared Neighborhood Hits	27
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

SLK_MOUSE
NC score	0.008870 (rank : 512)	θ value	1.06291 (rank : 257)
Query Neighborhood Hits	436	Target Neighborhood Hits	1798	Shared Neighborhood Hits	105
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

UCHL1_MOUSE
NC score	0.008722 (rank : 513)	θ value	6.88961 (rank : 404)
Query Neighborhood Hits	436	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0P9, Q9R122	Gene names	Uchl1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase isozyme L1 (EC 3.4.19.12) (EC 6.-.-.-) (UCH-L1) (Ubiquitin thioesterase L1) (Neuron cytoplasmic protein 9.5) (PGP 9.5) (PGP9.5).

SH2D3_MOUSE
NC score	0.008522 (rank : 514)	θ value	4.03905 (rank : 341)
Query Neighborhood Hits	436	Target Neighborhood Hits	174	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QZS8, Q9JME1	Gene names	Sh2d3c, Chat, Shep1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (SH2 domain-containing Eph receptor- binding protein 1) (Cas/HEF1-associated signal transducer).

MICA3_HUMAN
NC score	0.008095 (rank : 515)	θ value	1.81305 (rank : 272)
Query Neighborhood Hits	436	Target Neighborhood Hits	160	Shared Neighborhood Hits	6
SwissProt Accessions	Q7RTP6, Q6ICK4, Q9P2I3	Gene names	MICAL3, KIAA1364
Domain Architecture
Description	Protein MICAL-3.

COEA1_MOUSE
NC score	0.008080 (rank : 516)	θ value	0.62314 (rank : 232)
Query Neighborhood Hits	436	Target Neighborhood Hits	402	Shared Neighborhood Hits	11
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

G3BP_MOUSE
NC score	0.007598 (rank : 517)	θ value	8.99809 (rank : 416)
Query Neighborhood Hits	436	Target Neighborhood Hits	209	Shared Neighborhood Hits	7
SwissProt Accessions	P97855	Gene names	G3bp, G3bp1
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 1 (EC 3.6.1.-) (ATP- dependent DNA helicase VIII) (GAP SH3-domain-binding protein 1) (G3BP- 1) (HDH-VIII).

MCR_MOUSE
NC score	0.007449 (rank : 518)	θ value	5.27518 (rank : 361)
Query Neighborhood Hits	436	Target Neighborhood Hits	162	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

JPH4_MOUSE
NC score	0.007341 (rank : 519)	θ value	5.27518 (rank : 358)
Query Neighborhood Hits	436	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	Q80WT0, Q8BMI1	Gene names	Jph4, Jphl1
Domain Architecture	No domain graphic available
Description	Junctophilin-4 (Junctophilin-like 1 protein).

PTN23_MOUSE
NC score	0.006931 (rank : 520)	θ value	8.99809 (rank : 427)
Query Neighborhood Hits	436	Target Neighborhood Hits	726	Shared Neighborhood Hits	43
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

TCPH_MOUSE
NC score	0.006871 (rank : 521)	θ value	3.0926 (rank : 323)
Query Neighborhood Hits	436	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	P80313	Gene names	Cct7, Ccth
Domain Architecture
Description	T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta).

SLK_HUMAN
NC score	0.006354 (rank : 522)	θ value	8.99809 (rank : 433)
Query Neighborhood Hits	436	Target Neighborhood Hits	1775	Shared Neighborhood Hits	97
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

FGD1_HUMAN
NC score	0.005540 (rank : 523)	θ value	5.27518 (rank : 357)
Query Neighborhood Hits	436	Target Neighborhood Hits	367	Shared Neighborhood Hits	22
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

SUHW4_HUMAN
NC score	0.005128 (rank : 524)	θ value	5.27518 (rank : 368)
Query Neighborhood Hits	436	Target Neighborhood Hits	860	Shared Neighborhood Hits	47
SwissProt Accessions	Q6N043, Q6MZM6, Q6N085, Q9H0U5, Q9HCI8, Q9NXS0	Gene names	SUHW4, KIAA1584
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

DPF3_MOUSE
NC score	0.005051 (rank : 525)	θ value	6.88961 (rank : 378)
Query Neighborhood Hits	436	Target Neighborhood Hits	327	Shared Neighborhood Hits	3
SwissProt Accessions	P58269	Gene names	Dpf3, Cerd4
Domain Architecture	No domain graphic available
Description	Zinc-finger protein Dpf3 (cer-d4).

CD2L1_HUMAN
NC score	0.004803 (rank : 526)	θ value	6.88961 (rank : 376)
Query Neighborhood Hits	436	Target Neighborhood Hits	1467	Shared Neighborhood Hits	65
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

COEA1_HUMAN
NC score	0.004665 (rank : 527)	θ value	5.27518 (rank : 354)
Query Neighborhood Hits	436	Target Neighborhood Hits	427	Shared Neighborhood Hits	10
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

WNK1_HUMAN
NC score	0.004503 (rank : 528)	θ value	0.279714 (rank : 208)
Query Neighborhood Hits	436	Target Neighborhood Hits	1158	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

PDE4A_HUMAN
NC score	0.004408 (rank : 529)	θ value	3.0926 (rank : 316)
Query Neighborhood Hits	436	Target Neighborhood Hits	73	Shared Neighborhood Hits	3
SwissProt Accessions	P27815, O75522, O76092, Q16255, Q16691, Q8WUQ3	Gene names	PDE4A
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4A (EC 3.1.4.17) (DPDE2) (PDE46).

CD45_HUMAN
NC score	0.004287 (rank : 530)	θ value	4.03905 (rank : 326)
Query Neighborhood Hits	436	Target Neighborhood Hits	243	Shared Neighborhood Hits	15
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

CSPG2_HUMAN
NC score	0.003821 (rank : 531)	θ value	1.38821 (rank : 262)
Query Neighborhood Hits	436	Target Neighborhood Hits	681	Shared Neighborhood Hits	19
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

ATS19_MOUSE
NC score	0.002752 (rank : 532)	θ value	2.36792 (rank : 282)
Query Neighborhood Hits	436	Target Neighborhood Hits	188	Shared Neighborhood Hits	6
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

TS1R1_MOUSE
NC score	0.002738 (rank : 533)	θ value	6.88961 (rank : 403)
Query Neighborhood Hits	436	Target Neighborhood Hits	57	Shared Neighborhood Hits	2
SwissProt Accessions	Q99PG6, Q6NS58, Q923J9, Q925I5, Q99PG5	Gene names	Tas1r1, Gpr70, T1r1, Tr1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70).

CD2L2_HUMAN
NC score	0.002516 (rank : 534)	θ value	6.88961 (rank : 377)
Query Neighborhood Hits	436	Target Neighborhood Hits	1439	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

PTN21_MOUSE
NC score	0.002414 (rank : 535)	θ value	6.88961 (rank : 396)
Query Neighborhood Hits	436	Target Neighborhood Hits	155	Shared Neighborhood Hits	10
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

GAK_HUMAN
NC score	0.002402 (rank : 536)	θ value	0.47712 (rank : 221)
Query Neighborhood Hits	436	Target Neighborhood Hits	1028	Shared Neighborhood Hits	24
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

RHG07_HUMAN
NC score	0.002255 (rank : 537)	θ value	8.99809 (rank : 430)
Query Neighborhood Hits	436	Target Neighborhood Hits	108	Shared Neighborhood Hits	6
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RBM19_MOUSE
NC score	0.002157 (rank : 538)	θ value	8.99809 (rank : 428)
Query Neighborhood Hits	436	Target Neighborhood Hits	296	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R3C6, Q8BHR0, Q9CW63	Gene names	Rbm19
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

DDX54_MOUSE
NC score	0.002135 (rank : 539)	θ value	4.03905 (rank : 329)
Query Neighborhood Hits	436	Target Neighborhood Hits	124	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

TBX18_HUMAN
NC score	0.002125 (rank : 540)	θ value	6.88961 (rank : 401)
Query Neighborhood Hits	436	Target Neighborhood Hits	148	Shared Neighborhood Hits	4
SwissProt Accessions	O95935, Q7Z6U4, Q9UJI6	Gene names	TBX18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

PHLPP_MOUSE
NC score	0.001199 (rank : 541)	θ value	5.27518 (rank : 364)
Query Neighborhood Hits	436	Target Neighborhood Hits	394	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

FOXN3_HUMAN
NC score	0.000885 (rank : 542)	θ value	8.99809 (rank : 415)
Query Neighborhood Hits	436	Target Neighborhood Hits	121	Shared Neighborhood Hits	6
SwissProt Accessions	O00409, Q96II7, Q9UIE7	Gene names	CHES1, FOXN3
Domain Architecture
Description	Checkpoint suppressor 1 (Forkhead box protein N3).

SUHW4_MOUSE
NC score	0.000700 (rank : 543)	θ value	4.03905 (rank : 342)
Query Neighborhood Hits	436	Target Neighborhood Hits	737	Shared Neighborhood Hits	19
SwissProt Accessions	Q68FE8, Q3T9B1, Q8BI82	Gene names	Suhw4
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

HIPK3_MOUSE
NC score	-0.000186 (rank : 544)	θ value	3.0926 (rank : 309)
Query Neighborhood Hits	436	Target Neighborhood Hits	857	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ERH7, O88906, Q9QZR2	Gene names	Hipk3, Fist3
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Fas- interacting serine/threonine-protein kinase) (FIST) (Nuclear body- associated kinase 3) (Nbak3) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

ULK1_MOUSE
NC score	-0.001914 (rank : 545)	θ value	1.06291 (rank : 258)
Query Neighborhood Hits	436	Target Neighborhood Hits	1214	Shared Neighborhood Hits	36
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

SN1L1_MOUSE
NC score	-0.002931 (rank : 546)	θ value	0.62314 (rank : 237)
Query Neighborhood Hits	436	Target Neighborhood Hits	895	Shared Neighborhood Hits	23
SwissProt Accessions	Q60670	Gene names	Snf1lk, Msk
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1- like kinase).

MAST2_MOUSE
NC score	-0.003463 (rank : 547)	θ value	8.99809 (rank : 422)
Query Neighborhood Hits	436	Target Neighborhood Hits	1110	Shared Neighborhood Hits	33
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

CHK2_HUMAN
NC score	-0.003526 (rank : 548)	θ value	1.81305 (rank : 269)
Query Neighborhood Hits	436	Target Neighborhood Hits	859	Shared Neighborhood Hits	17
SwissProt Accessions	O96017, Q6QA03, Q6QA04, Q6QA05, Q6QA06, Q6QA07, Q6QA08, Q6QA10, Q6QA11, Q6QA12, Q6QA13, Q9HCQ8, Q9UGF0, Q9UGF1	Gene names	CHEK2, CHK2
Domain Architecture
Description	Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (Cds1).

CD97_HUMAN
NC score	-0.003803 (rank : 549)	θ value	8.99809 (rank : 409)
Query Neighborhood Hits	436	Target Neighborhood Hits	353	Shared Neighborhood Hits	4
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).