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Network neighborhood for query Sequence : NEURL_MOUSE

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NEURL_MOUSE
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NEUL1_HUMAN
θ value	0 (rank : 1)	NC score	0.997345 (rank : 2)
Query Neighborhood Hits	106	Target Neighborhood Hits	114	Shared Neighborhood Hits	102
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

NEURL_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	106	Target Neighborhood Hits	106	Shared Neighborhood Hits	106
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

NEUL2_MOUSE
θ value	5.26297e-08 (rank : 3)	NC score	0.365775 (rank : 10)
Query Neighborhood Hits	106	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D0S4	Gene names	Neurl2, Ozz
Domain Architecture
Description	Neuralized-like protein 2.

NEUL2_HUMAN
θ value	6.87365e-08 (rank : 4)	NC score	0.364832 (rank : 11)
Query Neighborhood Hits	106	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BR09, Q3KR34	Gene names	NEURL2, C20orf163
Domain Architecture
Description	Neuralized-like protein 2.

LRSM1_MOUSE
θ value	4.92598e-06 (rank : 5)	NC score	0.202270 (rank : 30)
Query Neighborhood Hits	106	Target Neighborhood Hits	874	Shared Neighborhood Hits	69
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

MGRN1_HUMAN
θ value	8.40245e-06 (rank : 6)	NC score	0.378116 (rank : 9)
Query Neighborhood Hits	106	Target Neighborhood Hits	192	Shared Neighborhood Hits	68
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

MGRN1_MOUSE
θ value	1.09739e-05 (rank : 7)	NC score	0.384766 (rank : 8)
Query Neighborhood Hits	106	Target Neighborhood Hits	149	Shared Neighborhood Hits	65
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

LRSM1_HUMAN
θ value	1.87187e-05 (rank : 8)	NC score	0.180973 (rank : 39)
Query Neighborhood Hits	106	Target Neighborhood Hits	1078	Shared Neighborhood Hits	66
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

RFFL_HUMAN
θ value	2.44474e-05 (rank : 9)	NC score	0.411612 (rank : 7)
Query Neighborhood Hits	106	Target Neighborhood Hits	175	Shared Neighborhood Hits	70
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RFFL_MOUSE
θ value	2.44474e-05 (rank : 10)	NC score	0.417552 (rank : 3)
Query Neighborhood Hits	106	Target Neighborhood Hits	145	Shared Neighborhood Hits	70
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

BIRC3_HUMAN
θ value	3.19293e-05 (rank : 11)	NC score	0.337013 (rank : 14)
Query Neighborhood Hits	106	Target Neighborhood Hits	133	Shared Neighborhood Hits	70
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

BIRC2_MOUSE
θ value	4.1701e-05 (rank : 12)	NC score	0.332890 (rank : 16)
Query Neighborhood Hits	106	Target Neighborhood Hits	137	Shared Neighborhood Hits	68
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

RNF34_HUMAN
θ value	4.1701e-05 (rank : 13)	NC score	0.416166 (rank : 5)
Query Neighborhood Hits	106	Target Neighborhood Hits	153	Shared Neighborhood Hits	70
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RNF34_MOUSE
θ value	4.1701e-05 (rank : 14)	NC score	0.417399 (rank : 4)
Query Neighborhood Hits	106	Target Neighborhood Hits	160	Shared Neighborhood Hits	72
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

BIRC3_MOUSE
θ value	5.44631e-05 (rank : 15)	NC score	0.336278 (rank : 15)
Query Neighborhood Hits	106	Target Neighborhood Hits	113	Shared Neighborhood Hits	69
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

BIRC2_HUMAN
θ value	7.1131e-05 (rank : 16)	NC score	0.327355 (rank : 18)
Query Neighborhood Hits	106	Target Neighborhood Hits	142	Shared Neighborhood Hits	68
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

RNF26_HUMAN
θ value	0.00035302 (rank : 17)	NC score	0.415396 (rank : 6)
Query Neighborhood Hits	106	Target Neighborhood Hits	95	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

BIRC7_HUMAN
θ value	0.000602161 (rank : 18)	NC score	0.357331 (rank : 13)
Query Neighborhood Hits	106	Target Neighborhood Hits	185	Shared Neighborhood Hits	82
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

RKHD1_HUMAN
θ value	0.00102713 (rank : 19)	NC score	0.361027 (rank : 12)
Query Neighborhood Hits	106	Target Neighborhood Hits	163	Shared Neighborhood Hits	54
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

MDM2_HUMAN
θ value	0.00134147 (rank : 20)	NC score	0.263297 (rank : 21)
Query Neighborhood Hits	106	Target Neighborhood Hits	92	Shared Neighborhood Hits	30
SwissProt Accessions	Q00987, Q13226, Q13297, Q13298, Q13299, Q13300, Q13301, Q53XW0, Q71TW9, Q9UGI3, Q9UMT8	Gene names	MDM2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein) (Hdm2).

MDM4_HUMAN
θ value	0.00175202 (rank : 21)	NC score	0.266864 (rank : 20)
Query Neighborhood Hits	106	Target Neighborhood Hits	37	Shared Neighborhood Hits	27
SwissProt Accessions	O15151, Q6GS18, Q8IV83	Gene names	MDM4, MDMX
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

CGRF1_HUMAN
θ value	0.00390308 (rank : 22)	NC score	0.331589 (rank : 17)
Query Neighborhood Hits	106	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	Q99675, Q96BX2	Gene names	CGRRF1, CGR19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

TRI40_HUMAN
θ value	0.00509761 (rank : 23)	NC score	0.179038 (rank : 40)
Query Neighborhood Hits	106	Target Neighborhood Hits	279	Shared Neighborhood Hits	67
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

CGRF1_MOUSE
θ value	0.00665767 (rank : 24)	NC score	0.321994 (rank : 19)
Query Neighborhood Hits	106	Target Neighborhood Hits	47	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BMJ7, Q3U3F1, Q8CI24	Gene names	Cgrrf1, Cgr19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

MDM2_MOUSE
θ value	0.00665767 (rank : 25)	NC score	0.243313 (rank : 23)
Query Neighborhood Hits	106	Target Neighborhood Hits	77	Shared Neighborhood Hits	28
SwissProt Accessions	P23804, Q61040, Q64330	Gene names	Mdm2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein).

MIB1_HUMAN
θ value	0.00665767 (rank : 26)	NC score	0.138366 (rank : 53)
Query Neighborhood Hits	106	Target Neighborhood Hits	470	Shared Neighborhood Hits	66
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	0.00665767 (rank : 27)	NC score	0.139609 (rank : 51)
Query Neighborhood Hits	106	Target Neighborhood Hits	471	Shared Neighborhood Hits	66
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

MYLIP_HUMAN
θ value	0.00665767 (rank : 28)	NC score	0.194283 (rank : 33)
Query Neighborhood Hits	106	Target Neighborhood Hits	162	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

RNF8_HUMAN
θ value	0.0148317 (rank : 29)	NC score	0.177166 (rank : 41)
Query Neighborhood Hits	106	Target Neighborhood Hits	622	Shared Neighborhood Hits	72
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

MIB2_HUMAN
θ value	0.0193708 (rank : 30)	NC score	0.129144 (rank : 58)
Query Neighborhood Hits	106	Target Neighborhood Hits	438	Shared Neighborhood Hits	52
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

MIB2_MOUSE
θ value	0.0193708 (rank : 31)	NC score	0.126791 (rank : 62)
Query Neighborhood Hits	106	Target Neighborhood Hits	409	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

MYLIP_MOUSE
θ value	0.0193708 (rank : 32)	NC score	0.169579 (rank : 44)
Query Neighborhood Hits	106	Target Neighborhood Hits	139	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

MDM4_MOUSE
θ value	0.0252991 (rank : 33)	NC score	0.207531 (rank : 27)
Query Neighborhood Hits	106	Target Neighborhood Hits	36	Shared Neighborhood Hits	21
SwissProt Accessions	O35618	Gene names	Mdm4, Mdmx
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

RN168_HUMAN
θ value	0.0330416 (rank : 34)	NC score	0.204465 (rank : 29)
Query Neighborhood Hits	106	Target Neighborhood Hits	370	Shared Neighborhood Hits	74
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI26_HUMAN
θ value	0.0431538 (rank : 35)	NC score	0.151280 (rank : 47)
Query Neighborhood Hits	106	Target Neighborhood Hits	335	Shared Neighborhood Hits	78
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI26_MOUSE
θ value	0.0431538 (rank : 36)	NC score	0.153842 (rank : 46)
Query Neighborhood Hits	106	Target Neighborhood Hits	339	Shared Neighborhood Hits	80
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

CBL_HUMAN
θ value	0.0736092 (rank : 37)	NC score	0.198192 (rank : 31)
Query Neighborhood Hits	106	Target Neighborhood Hits	353	Shared Neighborhood Hits	72
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBL_MOUSE
θ value	0.0736092 (rank : 38)	NC score	0.193872 (rank : 36)
Query Neighborhood Hits	106	Target Neighborhood Hits	426	Shared Neighborhood Hits	73
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

PEX12_HUMAN
θ value	0.0736092 (rank : 39)	NC score	0.139554 (rank : 52)
Query Neighborhood Hits	106	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	O00623	Gene names	PEX12, PAF3
Domain Architecture
Description	Peroxisome assembly protein 12 (Peroxin-12) (Peroxisome assembly factor 3) (PAF-3).

PEX12_MOUSE
θ value	0.0736092 (rank : 40)	NC score	0.138006 (rank : 54)
Query Neighborhood Hits	106	Target Neighborhood Hits	38	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VC48	Gene names	Pex12
Domain Architecture
Description	Peroxisome assembly protein 12 (Peroxin-12).

RN168_MOUSE
θ value	0.0736092 (rank : 41)	NC score	0.182908 (rank : 38)
Query Neighborhood Hits	106	Target Neighborhood Hits	440	Shared Neighborhood Hits	69
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

CBLB_HUMAN
θ value	0.0961366 (rank : 42)	NC score	0.193994 (rank : 35)
Query Neighborhood Hits	106	Target Neighborhood Hits	261	Shared Neighborhood Hits	70
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
θ value	0.0961366 (rank : 43)	NC score	0.194206 (rank : 34)
Query Neighborhood Hits	106	Target Neighborhood Hits	277	Shared Neighborhood Hits	70
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

MISS_MOUSE
θ value	0.163984 (rank : 44)	NC score	0.073293 (rank : 131)
Query Neighborhood Hits	106	Target Neighborhood Hits	444	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

RAG1_MOUSE
θ value	0.21417 (rank : 45)	NC score	0.128884 (rank : 61)
Query Neighborhood Hits	106	Target Neighborhood Hits	189	Shared Neighborhood Hits	48
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

RO52_MOUSE
θ value	0.21417 (rank : 46)	NC score	0.114741 (rank : 69)
Query Neighborhood Hits	106	Target Neighborhood Hits	360	Shared Neighborhood Hits	73
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

SMRA3_HUMAN
θ value	0.21417 (rank : 47)	NC score	0.115263 (rank : 68)
Query Neighborhood Hits	106	Target Neighborhood Hits	265	Shared Neighborhood Hits	61
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

TRI43_HUMAN
θ value	0.279714 (rank : 48)	NC score	0.113665 (rank : 73)
Query Neighborhood Hits	106	Target Neighborhood Hits	341	Shared Neighborhood Hits	69
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

CBLC_HUMAN
θ value	0.365318 (rank : 49)	NC score	0.195949 (rank : 32)
Query Neighborhood Hits	106	Target Neighborhood Hits	173	Shared Neighborhood Hits	69
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

CBLC_MOUSE
θ value	0.365318 (rank : 50)	NC score	0.193361 (rank : 37)
Query Neighborhood Hits	106	Target Neighborhood Hits	186	Shared Neighborhood Hits	67
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

RAG1_HUMAN
θ value	0.365318 (rank : 51)	NC score	0.123523 (rank : 63)
Query Neighborhood Hits	106	Target Neighborhood Hits	203	Shared Neighborhood Hits	44
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RN125_HUMAN
θ value	0.365318 (rank : 52)	NC score	0.148013 (rank : 48)
Query Neighborhood Hits	106	Target Neighborhood Hits	230	Shared Neighborhood Hits	60
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

RO52_HUMAN
θ value	0.365318 (rank : 53)	NC score	0.116758 (rank : 67)
Query Neighborhood Hits	106	Target Neighborhood Hits	419	Shared Neighborhood Hits	78
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

SMRA3_MOUSE
θ value	0.365318 (rank : 54)	NC score	0.118153 (rank : 66)
Query Neighborhood Hits	106	Target Neighborhood Hits	267	Shared Neighborhood Hits	61
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

TRI50_MOUSE
θ value	0.365318 (rank : 55)	NC score	0.119371 (rank : 65)
Query Neighborhood Hits	106	Target Neighborhood Hits	326	Shared Neighborhood Hits	81
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI68_MOUSE
θ value	0.365318 (rank : 56)	NC score	0.098654 (rank : 88)
Query Neighborhood Hits	106	Target Neighborhood Hits	356	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

ZN179_HUMAN
θ value	0.365318 (rank : 57)	NC score	0.139721 (rank : 50)
Query Neighborhood Hits	106	Target Neighborhood Hits	178	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

RN185_HUMAN
θ value	0.47712 (rank : 58)	NC score	0.214884 (rank : 26)
Query Neighborhood Hits	106	Target Neighborhood Hits	213	Shared Neighborhood Hits	68
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
θ value	0.47712 (rank : 59)	NC score	0.207146 (rank : 28)
Query Neighborhood Hits	106	Target Neighborhood Hits	211	Shared Neighborhood Hits	68
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RNF37_MOUSE
θ value	0.47712 (rank : 60)	NC score	0.096514 (rank : 89)
Query Neighborhood Hits	106	Target Neighborhood Hits	102	Shared Neighborhood Hits	31
SwissProt Accessions	Q925F4	Gene names	Ubox5, Rnf37, Ubce7ip5, Uip5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (UbcM4-interacting protein 5) (U-box domain-containing protein 5).

RNF8_MOUSE
θ value	0.47712 (rank : 61)	NC score	0.162400 (rank : 45)
Query Neighborhood Hits	106	Target Neighborhood Hits	618	Shared Neighborhood Hits	73
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

SIA1A_MOUSE
θ value	0.47712 (rank : 62)	NC score	0.128958 (rank : 60)
Query Neighborhood Hits	106	Target Neighborhood Hits	72	Shared Neighborhood Hits	31
SwissProt Accessions	P61092, Q06984	Gene names	Siah1a
Domain Architecture
Description	Ubiquitin ligase SIAH1A (EC 6.3.2.-) (Seven in absentia homolog 1a) (Siah1a) (Siah-1a) (mSiah-1a).

SIA1B_MOUSE
θ value	0.47712 (rank : 63)	NC score	0.130301 (rank : 57)
Query Neighborhood Hits	106	Target Neighborhood Hits	69	Shared Neighborhood Hits	31
SwissProt Accessions	Q06985, Q7TPV6	Gene names	Siah1b
Domain Architecture
Description	Ubiquitin ligase SIAH1B (EC 6.3.2.-) (Seven in absentia homolog 1b) (Siah1b) (Siah-1b).

SIAH1_HUMAN
θ value	0.47712 (rank : 64)	NC score	0.129138 (rank : 59)
Query Neighborhood Hits	106	Target Neighborhood Hits	72	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IUQ4, O43269, Q92880	Gene names	SIAH1, HUMSIAH
Domain Architecture
Description	Ubiquitin ligase SIAH1 (EC 6.3.2.-) (Seven in absentia homolog 1) (Siah-1) (Siah-1a).

CNOT4_HUMAN
θ value	0.813845 (rank : 65)	NC score	0.090372 (rank : 102)
Query Neighborhood Hits	106	Target Neighborhood Hits	207	Shared Neighborhood Hits	24
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CNOT4_MOUSE
θ value	0.813845 (rank : 66)	NC score	0.086606 (rank : 106)
Query Neighborhood Hits	106	Target Neighborhood Hits	277	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

TRI39_HUMAN
θ value	0.813845 (rank : 67)	NC score	0.102107 (rank : 82)
Query Neighborhood Hits	106	Target Neighborhood Hits	693	Shared Neighborhood Hits	69
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI39_MOUSE
θ value	0.813845 (rank : 68)	NC score	0.100692 (rank : 85)
Query Neighborhood Hits	106	Target Neighborhood Hits	691	Shared Neighborhood Hits	67
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI65_MOUSE
θ value	1.06291 (rank : 69)	NC score	0.113755 (rank : 72)
Query Neighborhood Hits	106	Target Neighborhood Hits	340	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TSC1_HUMAN
θ value	1.06291 (rank : 70)	NC score	0.025809 (rank : 186)
Query Neighborhood Hits	106	Target Neighborhood Hits	765	Shared Neighborhood Hits	8
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

BIRC4_HUMAN
θ value	1.38821 (rank : 71)	NC score	0.238347 (rank : 25)
Query Neighborhood Hits	106	Target Neighborhood Hits	89	Shared Neighborhood Hits	52
SwissProt Accessions	P98170, Q9NQ14	Gene names	BIRC4, API3, IAP3, XIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP).

BIRC4_MOUSE
θ value	1.38821 (rank : 72)	NC score	0.238354 (rank : 24)
Query Neighborhood Hits	106	Target Neighborhood Hits	89	Shared Neighborhood Hits	51
SwissProt Accessions	Q60989, O08865	Gene names	Birc4, Aipa, Api3, Miha, Xiap
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3).

RNF5_HUMAN
θ value	1.81305 (rank : 73)	NC score	0.175316 (rank : 42)
Query Neighborhood Hits	106	Target Neighborhood Hits	206	Shared Neighborhood Hits	66
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
θ value	1.81305 (rank : 74)	NC score	0.172845 (rank : 43)
Query Neighborhood Hits	106	Target Neighborhood Hits	206	Shared Neighborhood Hits	66
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

TRI60_HUMAN
θ value	1.81305 (rank : 75)	NC score	0.102191 (rank : 81)
Query Neighborhood Hits	106	Target Neighborhood Hits	357	Shared Neighborhood Hits	74
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

BCR_HUMAN
θ value	2.36792 (rank : 76)	NC score	0.016944 (rank : 188)
Query Neighborhood Hits	106	Target Neighborhood Hits	204	Shared Neighborhood Hits	5
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

BIRC8_HUMAN
θ value	2.36792 (rank : 77)	NC score	0.258248 (rank : 22)
Query Neighborhood Hits	106	Target Neighborhood Hits	121	Shared Neighborhood Hits	59
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

SNPC2_MOUSE
θ value	2.36792 (rank : 78)	NC score	0.030396 (rank : 185)
Query Neighborhood Hits	106	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q91XA5, Q3UK17, Q8CBS9	Gene names	Snapc2
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 2 (SNAPc subunit 2) (snRNA- activating protein complex 45 kDa subunit) (SNAPc 45 kDa subunit) (Small nuclear RNA-activating complex polypeptide 2).

HMCN1_HUMAN
θ value	3.0926 (rank : 79)	NC score	0.004622 (rank : 194)
Query Neighborhood Hits	106	Target Neighborhood Hits	983	Shared Neighborhood Hits	5
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

SIAH2_HUMAN
θ value	3.0926 (rank : 80)	NC score	0.131083 (rank : 56)
Query Neighborhood Hits	106	Target Neighborhood Hits	94	Shared Neighborhood Hits	36
SwissProt Accessions	O43255, O43270	Gene names	SIAH2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (hSiah2).

SIAH2_MOUSE
θ value	3.0926 (rank : 81)	NC score	0.131550 (rank : 55)
Query Neighborhood Hits	106	Target Neighborhood Hits	101	Shared Neighborhood Hits	36
SwissProt Accessions	Q06986	Gene names	Siah2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (mSiah2).

SSPO_MOUSE
θ value	3.0926 (rank : 82)	NC score	0.013990 (rank : 189)
Query Neighborhood Hits	106	Target Neighborhood Hits	800	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

TRI35_HUMAN
θ value	3.0926 (rank : 83)	NC score	0.104448 (rank : 78)
Query Neighborhood Hits	106	Target Neighborhood Hits	382	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI37_HUMAN
θ value	3.0926 (rank : 84)	NC score	0.099771 (rank : 86)
Query Neighborhood Hits	106	Target Neighborhood Hits	307	Shared Neighborhood Hits	49
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
θ value	3.0926 (rank : 85)	NC score	0.099702 (rank : 87)
Query Neighborhood Hits	106	Target Neighborhood Hits	316	Shared Neighborhood Hits	49
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

CHFR_MOUSE
θ value	4.03905 (rank : 86)	NC score	0.113803 (rank : 71)
Query Neighborhood Hits	106	Target Neighborhood Hits	264	Shared Neighborhood Hits	54
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

RN123_HUMAN
θ value	4.03905 (rank : 87)	NC score	0.085395 (rank : 110)
Query Neighborhood Hits	106	Target Neighborhood Hits	175	Shared Neighborhood Hits	49
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN123_MOUSE
θ value	4.03905 (rank : 88)	NC score	0.087581 (rank : 105)
Query Neighborhood Hits	106	Target Neighborhood Hits	174	Shared Neighborhood Hits	51
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN125_MOUSE
θ value	4.03905 (rank : 89)	NC score	0.122691 (rank : 64)
Query Neighborhood Hits	106	Target Neighborhood Hits	220	Shared Neighborhood Hits	59
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

TRI50_HUMAN
θ value	4.03905 (rank : 90)	NC score	0.104336 (rank : 79)
Query Neighborhood Hits	106	Target Neighborhood Hits	294	Shared Neighborhood Hits	78
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

DVL3_MOUSE
θ value	5.27518 (rank : 91)	NC score	0.009163 (rank : 192)
Query Neighborhood Hits	106	Target Neighborhood Hits	198	Shared Neighborhood Hits	3
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

RL27A_HUMAN
θ value	5.27518 (rank : 92)	NC score	0.025508 (rank : 187)
Query Neighborhood Hits	106	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	P46776	Gene names	RPL27A
Domain Architecture
Description	60S ribosomal protein L27a.

TRAF7_HUMAN
θ value	5.27518 (rank : 93)	NC score	0.047586 (rank : 184)
Query Neighborhood Hits	106	Target Neighborhood Hits	482	Shared Neighborhood Hits	58
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRAF7_MOUSE
θ value	5.27518 (rank : 94)	NC score	0.048124 (rank : 183)
Query Neighborhood Hits	106	Target Neighborhood Hits	470	Shared Neighborhood Hits	58
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

BRCA1_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.100794 (rank : 84)
Query Neighborhood Hits	106	Target Neighborhood Hits	381	Shared Neighborhood Hits	61
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

BRCA1_MOUSE
θ value	6.88961 (rank : 96)	NC score	0.100890 (rank : 83)
Query Neighborhood Hits	106	Target Neighborhood Hits	436	Shared Neighborhood Hits	62
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

TRI27_MOUSE
θ value	6.88961 (rank : 97)	NC score	0.091490 (rank : 98)
Query Neighborhood Hits	106	Target Neighborhood Hits	261	Shared Neighborhood Hits	76
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI60_MOUSE
θ value	6.88961 (rank : 98)	NC score	0.085122 (rank : 111)
Query Neighborhood Hits	106	Target Neighborhood Hits	240	Shared Neighborhood Hits	50
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

F120C_HUMAN
θ value	8.99809 (rank : 99)	NC score	0.009913 (rank : 191)
Query Neighborhood Hits	106	Target Neighborhood Hits	91	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NX05	Gene names	FAM120C, CXorf17
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120C (Tumor antigen BJ-HCC-21).

MEFV_MOUSE
θ value	8.99809 (rank : 100)	NC score	0.067755 (rank : 146)
Query Neighborhood Hits	106	Target Neighborhood Hits	236	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

MUC5B_HUMAN
θ value	8.99809 (rank : 101)	NC score	0.013272 (rank : 190)
Query Neighborhood Hits	106	Target Neighborhood Hits	1020	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

RN146_HUMAN
θ value	8.99809 (rank : 102)	NC score	0.106608 (rank : 74)
Query Neighborhood Hits	106	Target Neighborhood Hits	162	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
θ value	8.99809 (rank : 103)	NC score	0.105343 (rank : 75)
Query Neighborhood Hits	106	Target Neighborhood Hits	161	Shared Neighborhood Hits	49
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

RN169_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.104555 (rank : 77)
Query Neighborhood Hits	106	Target Neighborhood Hits	203	Shared Neighborhood Hits	42
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

SEZ6L_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.008301 (rank : 193)
Query Neighborhood Hits	106	Target Neighborhood Hits	289	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

TRI17_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.090515 (rank : 101)
Query Neighborhood Hits	106	Target Neighborhood Hits	318	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

AMFR2_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.064980 (rank : 151)
Query Neighborhood Hits	106	Target Neighborhood Hits	219	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

AMFR_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.064415 (rank : 155)
Query Neighborhood Hits	106	Target Neighborhood Hits	208	Shared Neighborhood Hits	51
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

BFAR_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.078901 (rank : 121)
Query Neighborhood Hits	106	Target Neighborhood Hits	222	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

BFAR_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.084909 (rank : 113)
Query Neighborhood Hits	106	Target Neighborhood Hits	232	Shared Neighborhood Hits	56
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

BIR1A_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.063627 (rank : 157)
Query Neighborhood Hits	106	Target Neighborhood Hits	94	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QWK5, Q9JIB5, Q9R017	Gene names	Birc1a, Naip, Naip1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1).

BIR1B_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.064924 (rank : 153)
Query Neighborhood Hits	106	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QUK4, O09124, Q9R030	Gene names	Birc1b, Naip-rs6, Naip2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2).

BIR1E_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.065262 (rank : 149)
Query Neighborhood Hits	106	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R016, O09121, O09122, P81703, Q9R029	Gene names	Birc1e, Naip-rs3, Naip5
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).

BIR1F_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.065154 (rank : 150)
Query Neighborhood Hits	106	Target Neighborhood Hits	88	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JIB6, O09121, O09122, P81704	Gene names	Birc1f, Naip-rs4, Naip6
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).

BIR1G_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.064972 (rank : 152)
Query Neighborhood Hits	106	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JIB3	Gene names	Birc1g, Naip7
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).

BIRC1_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.066032 (rank : 148)
Query Neighborhood Hits	106	Target Neighborhood Hits	61	Shared Neighborhood Hits	8
SwissProt Accessions	Q13075, O75857, Q13730, Q99796	Gene names	BIRC1, NAIP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein).

BIRC5_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.073276 (rank : 132)
Query Neighborhood Hits	106	Target Neighborhood Hits	20	Shared Neighborhood Hits	9
SwissProt Accessions	O15392, Q2I3N8, Q4VGX0, Q53F61, Q5MGC6, Q6FHL2, Q75SP2, Q9P2W8	Gene names	BIRC5, API4, IAP4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4).

BIRC5_MOUSE
θ value	θ > 10 (rank : 118)	NC score	0.077239 (rank : 126)
Query Neighborhood Hits	106	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	O70201, Q923F7, Q9WU53, Q9WU54	Gene names	Birc5, Api4, Iap4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4) (TIAP).

CHFR_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.094543 (rank : 93)
Query Neighborhood Hits	106	Target Neighborhood Hits	255	Shared Neighborhood Hits	51
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CM007_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.050678 (rank : 182)
Query Neighborhood Hits	106	Target Neighborhood Hits	422	Shared Neighborhood Hits	43
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

CM007_MOUSE
θ value	θ > 10 (rank : 121)	NC score	0.058008 (rank : 168)
Query Neighborhood Hits	106	Target Neighborhood Hits	416	Shared Neighborhood Hits	51
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

MEFV_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.053750 (rank : 177)
Query Neighborhood Hits	106	Target Neighborhood Hits	431	Shared Neighborhood Hits	22
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

PEX10_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.144275 (rank : 49)
Query Neighborhood Hits	106	Target Neighborhood Hits	255	Shared Neighborhood Hits	71
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

RFPL2_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.053608 (rank : 178)
Query Neighborhood Hits	106	Target Neighborhood Hits	126	Shared Neighborhood Hits	32
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

RFPL3_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.051175 (rank : 181)
Query Neighborhood Hits	106	Target Neighborhood Hits	134	Shared Neighborhood Hits	31
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

RFWD2_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.055332 (rank : 174)
Query Neighborhood Hits	106	Target Neighborhood Hits	535	Shared Neighborhood Hits	63
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

RING1_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.067961 (rank : 145)
Query Neighborhood Hits	106	Target Neighborhood Hits	219	Shared Neighborhood Hits	47
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.066658 (rank : 147)
Query Neighborhood Hits	106	Target Neighborhood Hits	220	Shared Neighborhood Hits	47
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RING2_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.061990 (rank : 162)
Query Neighborhood Hits	106	Target Neighborhood Hits	201	Shared Neighborhood Hits	44
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.061985 (rank : 163)
Query Neighborhood Hits	106	Target Neighborhood Hits	199	Shared Neighborhood Hits	44
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RN141_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.093764 (rank : 94)
Query Neighborhood Hits	106	Target Neighborhood Hits	199	Shared Neighborhood Hits	41
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.092739 (rank : 96)
Query Neighborhood Hits	106	Target Neighborhood Hits	200	Shared Neighborhood Hits	41
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN166_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.090594 (rank : 100)
Query Neighborhood Hits	106	Target Neighborhood Hits	240	Shared Neighborhood Hits	55
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
θ value	θ > 10 (rank : 134)	NC score	0.091733 (rank : 97)
Query Neighborhood Hits	106	Target Neighborhood Hits	248	Shared Neighborhood Hits	57
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RNF39_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.057735 (rank : 169)
Query Neighborhood Hits	106	Target Neighborhood Hits	200	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

RNF41_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.052012 (rank : 180)
Query Neighborhood Hits	106	Target Neighborhood Hits	226	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	θ > 10 (rank : 137)	NC score	0.052180 (rank : 179)
Query Neighborhood Hits	106	Target Neighborhood Hits	224	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF4_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.079459 (rank : 119)
Query Neighborhood Hits	106	Target Neighborhood Hits	212	Shared Neighborhood Hits	54
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
θ value	θ > 10 (rank : 139)	NC score	0.078034 (rank : 123)
Query Neighborhood Hits	106	Target Neighborhood Hits	212	Shared Neighborhood Hits	55
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

TOPRS_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.061118 (rank : 165)
Query Neighborhood Hits	106	Target Neighborhood Hits	286	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	θ > 10 (rank : 141)	NC score	0.064911 (rank : 154)
Query Neighborhood Hits	106	Target Neighborhood Hits	263	Shared Neighborhood Hits	50
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRAF6_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.054550 (rank : 175)
Query Neighborhood Hits	106	Target Neighborhood Hits	267	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRAF6_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.054270 (rank : 176)
Query Neighborhood Hits	106	Target Neighborhood Hits	255	Shared Neighborhood Hits	55
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

TRI10_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.081225 (rank : 116)
Query Neighborhood Hits	106	Target Neighborhood Hits	315	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI10_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.078577 (rank : 122)
Query Neighborhood Hits	106	Target Neighborhood Hits	285	Shared Neighborhood Hits	57
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI11_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.085424 (rank : 109)
Query Neighborhood Hits	106	Target Neighborhood Hits	316	Shared Neighborhood Hits	69
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI11_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.085695 (rank : 108)
Query Neighborhood Hits	106	Target Neighborhood Hits	329	Shared Neighborhood Hits	70
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI12_MOUSE
θ value	θ > 10 (rank : 148)	NC score	0.095699 (rank : 90)
Query Neighborhood Hits	106	Target Neighborhood Hits	387	Shared Neighborhood Hits	66
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI13_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.062412 (rank : 160)
Query Neighborhood Hits	106	Target Neighborhood Hits	274	Shared Neighborhood Hits	50
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI13_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.064324 (rank : 156)
Query Neighborhood Hits	106	Target Neighborhood Hits	282	Shared Neighborhood Hits	52
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI15_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.083754 (rank : 114)
Query Neighborhood Hits	106	Target Neighborhood Hits	395	Shared Neighborhood Hits	58
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI17_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.080547 (rank : 117)
Query Neighborhood Hits	106	Target Neighborhood Hits	620	Shared Neighborhood Hits	62
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI22_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.077647 (rank : 125)
Query Neighborhood Hits	106	Target Neighborhood Hits	396	Shared Neighborhood Hits	56
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI25_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.072696 (rank : 133)
Query Neighborhood Hits	106	Target Neighborhood Hits	472	Shared Neighborhood Hits	64
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI25_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.076870 (rank : 127)
Query Neighborhood Hits	106	Target Neighborhood Hits	446	Shared Neighborhood Hits	66
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI27_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.082955 (rank : 115)
Query Neighborhood Hits	106	Target Neighborhood Hits	273	Shared Neighborhood Hits	72
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI30_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.086294 (rank : 107)
Query Neighborhood Hits	106	Target Neighborhood Hits	434	Shared Neighborhood Hits	61
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRI31_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.105138 (rank : 76)
Query Neighborhood Hits	106	Target Neighborhood Hits	299	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI32_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.069751 (rank : 141)
Query Neighborhood Hits	106	Target Neighborhood Hits	264	Shared Neighborhood Hits	53
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI32_MOUSE
θ value	θ > 10 (rank : 160)	NC score	0.068806 (rank : 144)
Query Neighborhood Hits	106	Target Neighborhood Hits	271	Shared Neighborhood Hits	53
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRI34_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.076760 (rank : 128)
Query Neighborhood Hits	106	Target Neighborhood Hits	416	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI34_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.072458 (rank : 134)
Query Neighborhood Hits	106	Target Neighborhood Hits	332	Shared Neighborhood Hits	48
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI35_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.093258 (rank : 95)
Query Neighborhood Hits	106	Target Neighborhood Hits	465	Shared Neighborhood Hits	68
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI38_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.076062 (rank : 129)
Query Neighborhood Hits	106	Target Neighborhood Hits	373	Shared Neighborhood Hits	52
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRI41_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.071221 (rank : 137)
Query Neighborhood Hits	106	Target Neighborhood Hits	349	Shared Neighborhood Hits	53
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI47_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.069045 (rank : 143)
Query Neighborhood Hits	106	Target Neighborhood Hits	286	Shared Neighborhood Hits	62
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRI47_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.069792 (rank : 140)
Query Neighborhood Hits	106	Target Neighborhood Hits	295	Shared Neighborhood Hits	62
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRI48_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.080309 (rank : 118)
Query Neighborhood Hits	106	Target Neighborhood Hits	192	Shared Neighborhood Hits	52
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

TRI49_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.071651 (rank : 136)
Query Neighborhood Hits	106	Target Neighborhood Hits	199	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRI52_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.088911 (rank : 103)
Query Neighborhood Hits	106	Target Neighborhood Hits	213	Shared Neighborhood Hits	56
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI56_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.063489 (rank : 158)
Query Neighborhood Hits	106	Target Neighborhood Hits	339	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI56_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.055695 (rank : 172)
Query Neighborhood Hits	106	Target Neighborhood Hits	255	Shared Neighborhood Hits	56
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI59_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.060732 (rank : 166)
Query Neighborhood Hits	106	Target Neighborhood Hits	307	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI59_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.061674 (rank : 164)
Query Neighborhood Hits	106	Target Neighborhood Hits	292	Shared Neighborhood Hits	50
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI62_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.069441 (rank : 142)
Query Neighborhood Hits	106	Target Neighborhood Hits	584	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI62_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.070267 (rank : 139)
Query Neighborhood Hits	106	Target Neighborhood Hits	478	Shared Neighborhood Hits	51
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI65_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.094871 (rank : 92)
Query Neighborhood Hits	106	Target Neighborhood Hits	330	Shared Neighborhood Hits	63
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI68_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.079231 (rank : 120)
Query Neighborhood Hits	106	Target Neighborhood Hits	267	Shared Neighborhood Hits	57
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TRI73_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.095080 (rank : 91)
Query Neighborhood Hits	106	Target Neighborhood Hits	258	Shared Neighborhood Hits	67
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI74_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.090872 (rank : 99)
Query Neighborhood Hits	106	Target Neighborhood Hits	249	Shared Neighborhood Hits	65
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRIM2_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.062965 (rank : 159)
Query Neighborhood Hits	106	Target Neighborhood Hits	330	Shared Neighborhood Hits	59
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.062293 (rank : 161)
Query Neighborhood Hits	106	Target Neighborhood Hits	331	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRIM3_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.058584 (rank : 167)
Query Neighborhood Hits	106	Target Neighborhood Hits	357	Shared Neighborhood Hits	58
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRIM3_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.056526 (rank : 170)
Query Neighborhood Hits	106	Target Neighborhood Hits	351	Shared Neighborhood Hits	53
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRIM4_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.087933 (rank : 104)
Query Neighborhood Hits	106	Target Neighborhood Hits	321	Shared Neighborhood Hits	70
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRIM5_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.084949 (rank : 112)
Query Neighborhood Hits	106	Target Neighborhood Hits	424	Shared Neighborhood Hits	66
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRIM6_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.075705 (rank : 130)
Query Neighborhood Hits	106	Target Neighborhood Hits	412	Shared Neighborhood Hits	55
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRIM6_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.077911 (rank : 124)
Query Neighborhood Hits	106	Target Neighborhood Hits	451	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRIM7_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.070727 (rank : 138)
Query Neighborhood Hits	106	Target Neighborhood Hits	336	Shared Neighborhood Hits	48
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRIM7_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.072180 (rank : 135)
Query Neighborhood Hits	106	Target Neighborhood Hits	358	Shared Neighborhood Hits	48
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRIM8_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.055581 (rank : 173)
Query Neighborhood Hits	106	Target Neighborhood Hits	650	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.056442 (rank : 171)
Query Neighborhood Hits	106	Target Neighborhood Hits	674	Shared Neighborhood Hits	48
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

ZN313_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.103922 (rank : 80)
Query Neighborhood Hits	106	Target Neighborhood Hits	264	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

ZN313_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.114163 (rank : 70)
Query Neighborhood Hits	106	Target Neighborhood Hits	273	Shared Neighborhood Hits	67
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

Hits sorted by NC score

NEURL_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	106	Target Neighborhood Hits	106	Shared Neighborhood Hits	106
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

NEUL1_HUMAN
NC score	0.997345 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	106	Target Neighborhood Hits	114	Shared Neighborhood Hits	102
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

RFFL_MOUSE
NC score	0.417552 (rank : 3)	θ value	2.44474e-05 (rank : 10)
Query Neighborhood Hits	106	Target Neighborhood Hits	145	Shared Neighborhood Hits	70
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

RNF34_MOUSE
NC score	0.417399 (rank : 4)	θ value	4.1701e-05 (rank : 14)
Query Neighborhood Hits	106	Target Neighborhood Hits	160	Shared Neighborhood Hits	72
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

RNF34_HUMAN
NC score	0.416166 (rank : 5)	θ value	4.1701e-05 (rank : 13)
Query Neighborhood Hits	106	Target Neighborhood Hits	153	Shared Neighborhood Hits	70
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RNF26_HUMAN
NC score	0.415396 (rank : 6)	θ value	0.00035302 (rank : 17)
Query Neighborhood Hits	106	Target Neighborhood Hits	95	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

RFFL_HUMAN
NC score	0.411612 (rank : 7)	θ value	2.44474e-05 (rank : 9)
Query Neighborhood Hits	106	Target Neighborhood Hits	175	Shared Neighborhood Hits	70
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

MGRN1_MOUSE
NC score	0.384766 (rank : 8)	θ value	1.09739e-05 (rank : 7)
Query Neighborhood Hits	106	Target Neighborhood Hits	149	Shared Neighborhood Hits	65
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

MGRN1_HUMAN
NC score	0.378116 (rank : 9)	θ value	8.40245e-06 (rank : 6)
Query Neighborhood Hits	106	Target Neighborhood Hits	192	Shared Neighborhood Hits	68
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

NEUL2_MOUSE
NC score	0.365775 (rank : 10)	θ value	5.26297e-08 (rank : 3)
Query Neighborhood Hits	106	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D0S4	Gene names	Neurl2, Ozz
Domain Architecture
Description	Neuralized-like protein 2.

NEUL2_HUMAN
NC score	0.364832 (rank : 11)	θ value	6.87365e-08 (rank : 4)
Query Neighborhood Hits	106	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BR09, Q3KR34	Gene names	NEURL2, C20orf163
Domain Architecture
Description	Neuralized-like protein 2.

RKHD1_HUMAN
NC score	0.361027 (rank : 12)	θ value	0.00102713 (rank : 19)
Query Neighborhood Hits	106	Target Neighborhood Hits	163	Shared Neighborhood Hits	54
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

BIRC7_HUMAN
NC score	0.357331 (rank : 13)	θ value	0.000602161 (rank : 18)
Query Neighborhood Hits	106	Target Neighborhood Hits	185	Shared Neighborhood Hits	82
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

BIRC3_HUMAN
NC score	0.337013 (rank : 14)	θ value	3.19293e-05 (rank : 11)
Query Neighborhood Hits	106	Target Neighborhood Hits	133	Shared Neighborhood Hits	70
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

BIRC3_MOUSE
NC score	0.336278 (rank : 15)	θ value	5.44631e-05 (rank : 15)
Query Neighborhood Hits	106	Target Neighborhood Hits	113	Shared Neighborhood Hits	69
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

BIRC2_MOUSE
NC score	0.332890 (rank : 16)	θ value	4.1701e-05 (rank : 12)
Query Neighborhood Hits	106	Target Neighborhood Hits	137	Shared Neighborhood Hits	68
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

CGRF1_HUMAN
NC score	0.331589 (rank : 17)	θ value	0.00390308 (rank : 22)
Query Neighborhood Hits	106	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	Q99675, Q96BX2	Gene names	CGRRF1, CGR19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

BIRC2_HUMAN
NC score	0.327355 (rank : 18)	θ value	7.1131e-05 (rank : 16)
Query Neighborhood Hits	106	Target Neighborhood Hits	142	Shared Neighborhood Hits	68
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

CGRF1_MOUSE
NC score	0.321994 (rank : 19)	θ value	0.00665767 (rank : 24)
Query Neighborhood Hits	106	Target Neighborhood Hits	47	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BMJ7, Q3U3F1, Q8CI24	Gene names	Cgrrf1, Cgr19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

MDM4_HUMAN
NC score	0.266864 (rank : 20)	θ value	0.00175202 (rank : 21)
Query Neighborhood Hits	106	Target Neighborhood Hits	37	Shared Neighborhood Hits	27
SwissProt Accessions	O15151, Q6GS18, Q8IV83	Gene names	MDM4, MDMX
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

MDM2_HUMAN
NC score	0.263297 (rank : 21)	θ value	0.00134147 (rank : 20)
Query Neighborhood Hits	106	Target Neighborhood Hits	92	Shared Neighborhood Hits	30
SwissProt Accessions	Q00987, Q13226, Q13297, Q13298, Q13299, Q13300, Q13301, Q53XW0, Q71TW9, Q9UGI3, Q9UMT8	Gene names	MDM2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein) (Hdm2).

BIRC8_HUMAN
NC score	0.258248 (rank : 22)	θ value	2.36792 (rank : 77)
Query Neighborhood Hits	106	Target Neighborhood Hits	121	Shared Neighborhood Hits	59
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

MDM2_MOUSE
NC score	0.243313 (rank : 23)	θ value	0.00665767 (rank : 25)
Query Neighborhood Hits	106	Target Neighborhood Hits	77	Shared Neighborhood Hits	28
SwissProt Accessions	P23804, Q61040, Q64330	Gene names	Mdm2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein).

BIRC4_MOUSE
NC score	0.238354 (rank : 24)	θ value	1.38821 (rank : 72)
Query Neighborhood Hits	106	Target Neighborhood Hits	89	Shared Neighborhood Hits	51
SwissProt Accessions	Q60989, O08865	Gene names	Birc4, Aipa, Api3, Miha, Xiap
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3).

BIRC4_HUMAN
NC score	0.238347 (rank : 25)	θ value	1.38821 (rank : 71)
Query Neighborhood Hits	106	Target Neighborhood Hits	89	Shared Neighborhood Hits	52
SwissProt Accessions	P98170, Q9NQ14	Gene names	BIRC4, API3, IAP3, XIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP).

RN185_HUMAN
NC score	0.214884 (rank : 26)	θ value	0.47712 (rank : 58)
Query Neighborhood Hits	106	Target Neighborhood Hits	213	Shared Neighborhood Hits	68
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

MDM4_MOUSE
NC score	0.207531 (rank : 27)	θ value	0.0252991 (rank : 33)
Query Neighborhood Hits	106	Target Neighborhood Hits	36	Shared Neighborhood Hits	21
SwissProt Accessions	O35618	Gene names	Mdm4, Mdmx
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

RN185_MOUSE
NC score	0.207146 (rank : 28)	θ value	0.47712 (rank : 59)
Query Neighborhood Hits	106	Target Neighborhood Hits	211	Shared Neighborhood Hits	68
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN168_HUMAN
NC score	0.204465 (rank : 29)	θ value	0.0330416 (rank : 34)
Query Neighborhood Hits	106	Target Neighborhood Hits	370	Shared Neighborhood Hits	74
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

LRSM1_MOUSE
NC score	0.202270 (rank : 30)	θ value	4.92598e-06 (rank : 5)
Query Neighborhood Hits	106	Target Neighborhood Hits	874	Shared Neighborhood Hits	69
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

CBL_HUMAN
NC score	0.198192 (rank : 31)	θ value	0.0736092 (rank : 37)
Query Neighborhood Hits	106	Target Neighborhood Hits	353	Shared Neighborhood Hits	72
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBLC_HUMAN
NC score	0.195949 (rank : 32)	θ value	0.365318 (rank : 49)
Query Neighborhood Hits	106	Target Neighborhood Hits	173	Shared Neighborhood Hits	69
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

MYLIP_HUMAN
NC score	0.194283 (rank : 33)	θ value	0.00665767 (rank : 28)
Query Neighborhood Hits	106	Target Neighborhood Hits	162	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

CBLB_MOUSE
NC score	0.194206 (rank : 34)	θ value	0.0961366 (rank : 43)
Query Neighborhood Hits	106	Target Neighborhood Hits	277	Shared Neighborhood Hits	70
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CBLB_HUMAN
NC score	0.193994 (rank : 35)	θ value	0.0961366 (rank : 42)
Query Neighborhood Hits	106	Target Neighborhood Hits	261	Shared Neighborhood Hits	70
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBL_MOUSE
NC score	0.193872 (rank : 36)	θ value	0.0736092 (rank : 38)
Query Neighborhood Hits	106	Target Neighborhood Hits	426	Shared Neighborhood Hits	73
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CBLC_MOUSE
NC score	0.193361 (rank : 37)	θ value	0.365318 (rank : 50)
Query Neighborhood Hits	106	Target Neighborhood Hits	186	Shared Neighborhood Hits	67
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

RN168_MOUSE
NC score	0.182908 (rank : 38)	θ value	0.0736092 (rank : 41)
Query Neighborhood Hits	106	Target Neighborhood Hits	440	Shared Neighborhood Hits	69
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

LRSM1_HUMAN
NC score	0.180973 (rank : 39)	θ value	1.87187e-05 (rank : 8)
Query Neighborhood Hits	106	Target Neighborhood Hits	1078	Shared Neighborhood Hits	66
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

TRI40_HUMAN
NC score	0.179038 (rank : 40)	θ value	0.00509761 (rank : 23)
Query Neighborhood Hits	106	Target Neighborhood Hits	279	Shared Neighborhood Hits	67
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

RNF8_HUMAN
NC score	0.177166 (rank : 41)	θ value	0.0148317 (rank : 29)
Query Neighborhood Hits	106	Target Neighborhood Hits	622	Shared Neighborhood Hits	72
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RNF5_HUMAN
NC score	0.175316 (rank : 42)	θ value	1.81305 (rank : 73)
Query Neighborhood Hits	106	Target Neighborhood Hits	206	Shared Neighborhood Hits	66
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
NC score	0.172845 (rank : 43)	θ value	1.81305 (rank : 74)
Query Neighborhood Hits	106	Target Neighborhood Hits	206	Shared Neighborhood Hits	66
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

MYLIP_MOUSE
NC score	0.169579 (rank : 44)	θ value	0.0193708 (rank : 32)
Query Neighborhood Hits	106	Target Neighborhood Hits	139	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

RNF8_MOUSE
NC score	0.162400 (rank : 45)	θ value	0.47712 (rank : 61)
Query Neighborhood Hits	106	Target Neighborhood Hits	618	Shared Neighborhood Hits	73
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

TRI26_MOUSE
NC score	0.153842 (rank : 46)	θ value	0.0431538 (rank : 36)
Query Neighborhood Hits	106	Target Neighborhood Hits	339	Shared Neighborhood Hits	80
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI26_HUMAN
NC score	0.151280 (rank : 47)	θ value	0.0431538 (rank : 35)
Query Neighborhood Hits	106	Target Neighborhood Hits	335	Shared Neighborhood Hits	78
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

RN125_HUMAN
NC score	0.148013 (rank : 48)	θ value	0.365318 (rank : 52)
Query Neighborhood Hits	106	Target Neighborhood Hits	230	Shared Neighborhood Hits	60
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

PEX10_HUMAN
NC score	0.144275 (rank : 49)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	106	Target Neighborhood Hits	255	Shared Neighborhood Hits	71
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

ZN179_HUMAN
NC score	0.139721 (rank : 50)	θ value	0.365318 (rank : 57)
Query Neighborhood Hits	106	Target Neighborhood Hits	178	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

MIB1_MOUSE
NC score	0.139609 (rank : 51)	θ value	0.00665767 (rank : 27)
Query Neighborhood Hits	106	Target Neighborhood Hits	471	Shared Neighborhood Hits	66
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

PEX12_HUMAN
NC score	0.139554 (rank : 52)	θ value	0.0736092 (rank : 39)
Query Neighborhood Hits	106	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	O00623	Gene names	PEX12, PAF3
Domain Architecture
Description	Peroxisome assembly protein 12 (Peroxin-12) (Peroxisome assembly factor 3) (PAF-3).

MIB1_HUMAN
NC score	0.138366 (rank : 53)	θ value	0.00665767 (rank : 26)
Query Neighborhood Hits	106	Target Neighborhood Hits	470	Shared Neighborhood Hits	66
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

PEX12_MOUSE
NC score	0.138006 (rank : 54)	θ value	0.0736092 (rank : 40)
Query Neighborhood Hits	106	Target Neighborhood Hits	38	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VC48	Gene names	Pex12
Domain Architecture
Description	Peroxisome assembly protein 12 (Peroxin-12).

SIAH2_MOUSE
NC score	0.131550 (rank : 55)	θ value	3.0926 (rank : 81)
Query Neighborhood Hits	106	Target Neighborhood Hits	101	Shared Neighborhood Hits	36
SwissProt Accessions	Q06986	Gene names	Siah2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (mSiah2).

SIAH2_HUMAN
NC score	0.131083 (rank : 56)	θ value	3.0926 (rank : 80)
Query Neighborhood Hits	106	Target Neighborhood Hits	94	Shared Neighborhood Hits	36
SwissProt Accessions	O43255, O43270	Gene names	SIAH2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (hSiah2).

SIA1B_MOUSE
NC score	0.130301 (rank : 57)	θ value	0.47712 (rank : 63)
Query Neighborhood Hits	106	Target Neighborhood Hits	69	Shared Neighborhood Hits	31
SwissProt Accessions	Q06985, Q7TPV6	Gene names	Siah1b
Domain Architecture
Description	Ubiquitin ligase SIAH1B (EC 6.3.2.-) (Seven in absentia homolog 1b) (Siah1b) (Siah-1b).

MIB2_HUMAN
NC score	0.129144 (rank : 58)	θ value	0.0193708 (rank : 30)
Query Neighborhood Hits	106	Target Neighborhood Hits	438	Shared Neighborhood Hits	52
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

SIAH1_HUMAN
NC score	0.129138 (rank : 59)	θ value	0.47712 (rank : 64)
Query Neighborhood Hits	106	Target Neighborhood Hits	72	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IUQ4, O43269, Q92880	Gene names	SIAH1, HUMSIAH
Domain Architecture
Description	Ubiquitin ligase SIAH1 (EC 6.3.2.-) (Seven in absentia homolog 1) (Siah-1) (Siah-1a).

SIA1A_MOUSE
NC score	0.128958 (rank : 60)	θ value	0.47712 (rank : 62)
Query Neighborhood Hits	106	Target Neighborhood Hits	72	Shared Neighborhood Hits	31
SwissProt Accessions	P61092, Q06984	Gene names	Siah1a
Domain Architecture
Description	Ubiquitin ligase SIAH1A (EC 6.3.2.-) (Seven in absentia homolog 1a) (Siah1a) (Siah-1a) (mSiah-1a).

RAG1_MOUSE
NC score	0.128884 (rank : 61)	θ value	0.21417 (rank : 45)
Query Neighborhood Hits	106	Target Neighborhood Hits	189	Shared Neighborhood Hits	48
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

MIB2_MOUSE
NC score	0.126791 (rank : 62)	θ value	0.0193708 (rank : 31)
Query Neighborhood Hits	106	Target Neighborhood Hits	409	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

RAG1_HUMAN
NC score	0.123523 (rank : 63)	θ value	0.365318 (rank : 51)
Query Neighborhood Hits	106	Target Neighborhood Hits	203	Shared Neighborhood Hits	44
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RN125_MOUSE
NC score	0.122691 (rank : 64)	θ value	4.03905 (rank : 89)
Query Neighborhood Hits	106	Target Neighborhood Hits	220	Shared Neighborhood Hits	59
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

TRI50_MOUSE
NC score	0.119371 (rank : 65)	θ value	0.365318 (rank : 55)
Query Neighborhood Hits	106	Target Neighborhood Hits	326	Shared Neighborhood Hits	81
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

SMRA3_MOUSE
NC score	0.118153 (rank : 66)	θ value	0.365318 (rank : 54)
Query Neighborhood Hits	106	Target Neighborhood Hits	267	Shared Neighborhood Hits	61
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

RO52_HUMAN
NC score	0.116758 (rank : 67)	θ value	0.365318 (rank : 53)
Query Neighborhood Hits	106	Target Neighborhood Hits	419	Shared Neighborhood Hits	78
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

SMRA3_HUMAN
NC score	0.115263 (rank : 68)	θ value	0.21417 (rank : 47)
Query Neighborhood Hits	106	Target Neighborhood Hits	265	Shared Neighborhood Hits	61
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

RO52_MOUSE
NC score	0.114741 (rank : 69)	θ value	0.21417 (rank : 46)
Query Neighborhood Hits	106	Target Neighborhood Hits	360	Shared Neighborhood Hits	73
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

ZN313_MOUSE
NC score	0.114163 (rank : 70)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	106	Target Neighborhood Hits	273	Shared Neighborhood Hits	67
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

CHFR_MOUSE
NC score	0.113803 (rank : 71)	θ value	4.03905 (rank : 86)
Query Neighborhood Hits	106	Target Neighborhood Hits	264	Shared Neighborhood Hits	54
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

TRI65_MOUSE
NC score	0.113755 (rank : 72)	θ value	1.06291 (rank : 69)
Query Neighborhood Hits	106	Target Neighborhood Hits	340	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI43_HUMAN
NC score	0.113665 (rank : 73)	θ value	0.279714 (rank : 48)
Query Neighborhood Hits	106	Target Neighborhood Hits	341	Shared Neighborhood Hits	69
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

RN146_HUMAN
NC score	0.106608 (rank : 74)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	106	Target Neighborhood Hits	162	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
NC score	0.105343 (rank : 75)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	106	Target Neighborhood Hits	161	Shared Neighborhood Hits	49
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

TRI31_HUMAN
NC score	0.105138 (rank : 76)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	106	Target Neighborhood Hits	299	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

RN169_HUMAN
NC score	0.104555 (rank : 77)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	106	Target Neighborhood Hits	203	Shared Neighborhood Hits	42
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

TRI35_HUMAN
NC score	0.104448 (rank : 78)	θ value	3.0926 (rank : 83)
Query Neighborhood Hits	106	Target Neighborhood Hits	382	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI50_HUMAN
NC score	0.104336 (rank : 79)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	106	Target Neighborhood Hits	294	Shared Neighborhood Hits	78
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

ZN313_HUMAN
NC score	0.103922 (rank : 80)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	106	Target Neighborhood Hits	264	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

TRI60_HUMAN
NC score	0.102191 (rank : 81)	θ value	1.81305 (rank : 75)
Query Neighborhood Hits	106	Target Neighborhood Hits	357	Shared Neighborhood Hits	74
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRI39_HUMAN
NC score	0.102107 (rank : 82)	θ value	0.813845 (rank : 67)
Query Neighborhood Hits	106	Target Neighborhood Hits	693	Shared Neighborhood Hits	69
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

BRCA1_MOUSE
NC score	0.100890 (rank : 83)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	106	Target Neighborhood Hits	436	Shared Neighborhood Hits	62
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

BRCA1_HUMAN
NC score	0.100794 (rank : 84)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	106	Target Neighborhood Hits	381	Shared Neighborhood Hits	61
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

TRI39_MOUSE
NC score	0.100692 (rank : 85)	θ value	0.813845 (rank : 68)
Query Neighborhood Hits	106	Target Neighborhood Hits	691	Shared Neighborhood Hits	67
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI37_HUMAN
NC score	0.099771 (rank : 86)	θ value	3.0926 (rank : 84)
Query Neighborhood Hits	106	Target Neighborhood Hits	307	Shared Neighborhood Hits	49
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
NC score	0.099702 (rank : 87)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	106	Target Neighborhood Hits	316	Shared Neighborhood Hits	49
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI68_MOUSE
NC score	0.098654 (rank : 88)	θ value	0.365318 (rank : 56)
Query Neighborhood Hits	106	Target Neighborhood Hits	356	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

RNF37_MOUSE
NC score	0.096514 (rank : 89)	θ value	0.47712 (rank : 60)
Query Neighborhood Hits	106	Target Neighborhood Hits	102	Shared Neighborhood Hits	31
SwissProt Accessions	Q925F4	Gene names	Ubox5, Rnf37, Ubce7ip5, Uip5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (UbcM4-interacting protein 5) (U-box domain-containing protein 5).

TRI12_MOUSE
NC score	0.095699 (rank : 90)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	106	Target Neighborhood Hits	387	Shared Neighborhood Hits	66
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI73_HUMAN
NC score	0.095080 (rank : 91)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	106	Target Neighborhood Hits	258	Shared Neighborhood Hits	67
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI65_HUMAN
NC score	0.094871 (rank : 92)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	106	Target Neighborhood Hits	330	Shared Neighborhood Hits	63
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

CHFR_HUMAN
NC score	0.094543 (rank : 93)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	106	Target Neighborhood Hits	255	Shared Neighborhood Hits	51
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

RN141_HUMAN
NC score	0.093764 (rank : 94)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	106	Target Neighborhood Hits	199	Shared Neighborhood Hits	41
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

TRI35_MOUSE
NC score	0.093258 (rank : 95)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	106	Target Neighborhood Hits	465	Shared Neighborhood Hits	68
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

RN141_MOUSE
NC score	0.092739 (rank : 96)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	106	Target Neighborhood Hits	200	Shared Neighborhood Hits	41
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN166_MOUSE
NC score	0.091733 (rank : 97)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	106	Target Neighborhood Hits	248	Shared Neighborhood Hits	57
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

TRI27_MOUSE
NC score	0.091490 (rank : 98)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	106	Target Neighborhood Hits	261	Shared Neighborhood Hits	76
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI74_HUMAN
NC score	0.090872 (rank : 99)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	106	Target Neighborhood Hits	249	Shared Neighborhood Hits	65
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

RN166_HUMAN
NC score	0.090594 (rank : 100)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	106	Target Neighborhood Hits	240	Shared Neighborhood Hits	55
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

TRI17_HUMAN
NC score	0.090515 (rank : 101)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	106	Target Neighborhood Hits	318	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

CNOT4_HUMAN
NC score	0.090372 (rank : 102)	θ value	0.813845 (rank : 65)
Query Neighborhood Hits	106	Target Neighborhood Hits	207	Shared Neighborhood Hits	24
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

TRI52_HUMAN
NC score	0.088911 (rank : 103)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	106	Target Neighborhood Hits	213	Shared Neighborhood Hits	56
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRIM4_HUMAN
NC score	0.087933 (rank : 104)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	106	Target Neighborhood Hits	321	Shared Neighborhood Hits	70
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

RN123_MOUSE
NC score	0.087581 (rank : 105)	θ value	4.03905 (rank : 88)
Query Neighborhood Hits	106	Target Neighborhood Hits	174	Shared Neighborhood Hits	51
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

CNOT4_MOUSE
NC score	0.086606 (rank : 106)	θ value	0.813845 (rank : 66)
Query Neighborhood Hits	106	Target Neighborhood Hits	277	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

TRI30_MOUSE
NC score	0.086294 (rank : 107)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	106	Target Neighborhood Hits	434	Shared Neighborhood Hits	61
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRI11_MOUSE
NC score	0.085695 (rank : 108)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	106	Target Neighborhood Hits	329	Shared Neighborhood Hits	70
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI11_HUMAN
NC score	0.085424 (rank : 109)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	106	Target Neighborhood Hits	316	Shared Neighborhood Hits	69
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

RN123_HUMAN
NC score	0.085395 (rank : 110)	θ value	4.03905 (rank : 87)
Query Neighborhood Hits	106	Target Neighborhood Hits	175	Shared Neighborhood Hits	49
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

TRI60_MOUSE
NC score	0.085122 (rank : 111)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	106	Target Neighborhood Hits	240	Shared Neighborhood Hits	50
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRIM5_HUMAN
NC score	0.084949 (rank : 112)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	106	Target Neighborhood Hits	424	Shared Neighborhood Hits	66
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

BFAR_MOUSE
NC score	0.084909 (rank : 113)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	106	Target Neighborhood Hits	232	Shared Neighborhood Hits	56
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

TRI15_HUMAN
NC score	0.083754 (rank : 114)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	106	Target Neighborhood Hits	395	Shared Neighborhood Hits	58
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI27_HUMAN
NC score	0.082955 (rank : 115)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	106	Target Neighborhood Hits	273	Shared Neighborhood Hits	72
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI10_HUMAN
NC score	0.081225 (rank : 116)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	106	Target Neighborhood Hits	315	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI17_MOUSE
NC score	0.080547 (rank : 117)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	106	Target Neighborhood Hits	620	Shared Neighborhood Hits	62
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI48_HUMAN
NC score	0.080309 (rank : 118)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	106	Target Neighborhood Hits	192	Shared Neighborhood Hits	52
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

RNF4_HUMAN
NC score	0.079459 (rank : 119)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	106	Target Neighborhood Hits	212	Shared Neighborhood Hits	54
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

TRI68_HUMAN
NC score	0.079231 (rank : 120)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	106	Target Neighborhood Hits	267	Shared Neighborhood Hits	57
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

BFAR_HUMAN
NC score	0.078901 (rank : 121)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	106	Target Neighborhood Hits	222	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

TRI10_MOUSE
NC score	0.078577 (rank : 122)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	106	Target Neighborhood Hits	285	Shared Neighborhood Hits	57
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

RNF4_MOUSE
NC score	0.078034 (rank : 123)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	106	Target Neighborhood Hits	212	Shared Neighborhood Hits	55
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

TRIM6_MOUSE
NC score	0.077911 (rank : 124)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	106	Target Neighborhood Hits	451	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRI22_HUMAN
NC score	0.077647 (rank : 125)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	106	Target Neighborhood Hits	396	Shared Neighborhood Hits	56
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

BIRC5_MOUSE
NC score	0.077239 (rank : 126)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	106	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	O70201, Q923F7, Q9WU53, Q9WU54	Gene names	Birc5, Api4, Iap4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4) (TIAP).

TRI25_MOUSE
NC score	0.076870 (rank : 127)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	106	Target Neighborhood Hits	446	Shared Neighborhood Hits	66
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI34_HUMAN
NC score	0.076760 (rank : 128)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	106	Target Neighborhood Hits	416	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI38_HUMAN
NC score	0.076062 (rank : 129)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	106	Target Neighborhood Hits	373	Shared Neighborhood Hits	52
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRIM6_HUMAN
NC score	0.075705 (rank : 130)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	106	Target Neighborhood Hits	412	Shared Neighborhood Hits	55
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

MISS_MOUSE
NC score	0.073293 (rank : 131)	θ value	0.163984 (rank : 44)
Query Neighborhood Hits	106	Target Neighborhood Hits	444	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

BIRC5_HUMAN
NC score	0.073276 (rank : 132)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	106	Target Neighborhood Hits	20	Shared Neighborhood Hits	9
SwissProt Accessions	O15392, Q2I3N8, Q4VGX0, Q53F61, Q5MGC6, Q6FHL2, Q75SP2, Q9P2W8	Gene names	BIRC5, API4, IAP4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4).

TRI25_HUMAN
NC score	0.072696 (rank : 133)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	106	Target Neighborhood Hits	472	Shared Neighborhood Hits	64
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI34_MOUSE
NC score	0.072458 (rank : 134)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	106	Target Neighborhood Hits	332	Shared Neighborhood Hits	48
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRIM7_MOUSE
NC score	0.072180 (rank : 135)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	106	Target Neighborhood Hits	358	Shared Neighborhood Hits	48
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRI49_HUMAN
NC score	0.071651 (rank : 136)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	106	Target Neighborhood Hits	199	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRI41_HUMAN
NC score	0.071221 (rank : 137)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	106	Target Neighborhood Hits	349	Shared Neighborhood Hits	53
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRIM7_HUMAN
NC score	0.070727 (rank : 138)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	106	Target Neighborhood Hits	336	Shared Neighborhood Hits	48
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRI62_MOUSE
NC score	0.070267 (rank : 139)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	106	Target Neighborhood Hits	478	Shared Neighborhood Hits	51
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI47_MOUSE
NC score	0.069792 (rank : 140)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	106	Target Neighborhood Hits	295	Shared Neighborhood Hits	62
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRI32_HUMAN
NC score	0.069751 (rank : 141)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	106	Target Neighborhood Hits	264	Shared Neighborhood Hits	53
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI62_HUMAN
NC score	0.069441 (rank : 142)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	106	Target Neighborhood Hits	584	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI47_HUMAN
NC score	0.069045 (rank : 143)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	106	Target Neighborhood Hits	286	Shared Neighborhood Hits	62
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRI32_MOUSE
NC score	0.068806 (rank : 144)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	106	Target Neighborhood Hits	271	Shared Neighborhood Hits	53
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

RING1_HUMAN
NC score	0.067961 (rank : 145)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	106	Target Neighborhood Hits	219	Shared Neighborhood Hits	47
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

MEFV_MOUSE
NC score	0.067755 (rank : 146)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	106	Target Neighborhood Hits	236	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

RING1_MOUSE
NC score	0.066658 (rank : 147)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	106	Target Neighborhood Hits	220	Shared Neighborhood Hits	47
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

BIRC1_HUMAN
NC score	0.066032 (rank : 148)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	106	Target Neighborhood Hits	61	Shared Neighborhood Hits	8
SwissProt Accessions	Q13075, O75857, Q13730, Q99796	Gene names	BIRC1, NAIP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein).

BIR1E_MOUSE
NC score	0.065262 (rank : 149)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	106	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R016, O09121, O09122, P81703, Q9R029	Gene names	Birc1e, Naip-rs3, Naip5
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).

BIR1F_MOUSE
NC score	0.065154 (rank : 150)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	106	Target Neighborhood Hits	88	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JIB6, O09121, O09122, P81704	Gene names	Birc1f, Naip-rs4, Naip6
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).

AMFR2_HUMAN
NC score	0.064980 (rank : 151)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	106	Target Neighborhood Hits	219	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

BIR1G_MOUSE
NC score	0.064972 (rank : 152)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	106	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JIB3	Gene names	Birc1g, Naip7
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).

BIR1B_MOUSE
NC score	0.064924 (rank : 153)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	106	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QUK4, O09124, Q9R030	Gene names	Birc1b, Naip-rs6, Naip2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2).

TOPRS_MOUSE
NC score	0.064911 (rank : 154)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	106	Target Neighborhood Hits	263	Shared Neighborhood Hits	50
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

AMFR_MOUSE
NC score	0.064415 (rank : 155)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	106	Target Neighborhood Hits	208	Shared Neighborhood Hits	51
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

TRI13_MOUSE
NC score	0.064324 (rank : 156)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	106	Target Neighborhood Hits	282	Shared Neighborhood Hits	52
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

BIR1A_MOUSE
NC score	0.063627 (rank : 157)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	106	Target Neighborhood Hits	94	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QWK5, Q9JIB5, Q9R017	Gene names	Birc1a, Naip, Naip1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1).

TRI56_HUMAN
NC score	0.063489 (rank : 158)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	106	Target Neighborhood Hits	339	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRIM2_HUMAN
NC score	0.062965 (rank : 159)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	106	Target Neighborhood Hits	330	Shared Neighborhood Hits	59
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRI13_HUMAN
NC score	0.062412 (rank : 160)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	106	Target Neighborhood Hits	274	Shared Neighborhood Hits	50
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRIM2_MOUSE
NC score	0.062293 (rank : 161)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	106	Target Neighborhood Hits	331	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

RING2_HUMAN
NC score	0.061990 (rank : 162)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	106	Target Neighborhood Hits	201	Shared Neighborhood Hits	44
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
NC score	0.061985 (rank : 163)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	106	Target Neighborhood Hits	199	Shared Neighborhood Hits	44
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

TRI59_MOUSE
NC score	0.061674 (rank : 164)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	106	Target Neighborhood Hits	292	Shared Neighborhood Hits	50
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TOPRS_HUMAN
NC score	0.061118 (rank : 165)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	106	Target Neighborhood Hits	286	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRI59_HUMAN
NC score	0.060732 (rank : 166)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	106	Target Neighborhood Hits	307	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRIM3_HUMAN
NC score	0.058584 (rank : 167)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	106	Target Neighborhood Hits	357	Shared Neighborhood Hits	58
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

CM007_MOUSE
NC score	0.058008 (rank : 168)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	106	Target Neighborhood Hits	416	Shared Neighborhood Hits	51
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

RNF39_HUMAN
NC score	0.057735 (rank : 169)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	106	Target Neighborhood Hits	200	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

TRIM3_MOUSE
NC score	0.056526 (rank : 170)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	106	Target Neighborhood Hits	351	Shared Neighborhood Hits	53
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRIM8_MOUSE
NC score	0.056442 (rank : 171)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	106	Target Neighborhood Hits	674	Shared Neighborhood Hits	48
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRI56_MOUSE
NC score	0.055695 (rank : 172)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	106	Target Neighborhood Hits	255	Shared Neighborhood Hits	56
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRIM8_HUMAN
NC score	0.055581 (rank : 173)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	106	Target Neighborhood Hits	650	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

RFWD2_MOUSE
NC score	0.055332 (rank : 174)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	106	Target Neighborhood Hits	535	Shared Neighborhood Hits	63
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

TRAF6_HUMAN
NC score	0.054550 (rank : 175)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	106	Target Neighborhood Hits	267	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRAF6_MOUSE
NC score	0.054270 (rank : 176)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	106	Target Neighborhood Hits	255	Shared Neighborhood Hits	55
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

MEFV_HUMAN
NC score	0.053750 (rank : 177)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	106	Target Neighborhood Hits	431	Shared Neighborhood Hits	22
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

RFPL2_HUMAN
NC score	0.053608 (rank : 178)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	106	Target Neighborhood Hits	126	Shared Neighborhood Hits	32
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

RNF41_MOUSE
NC score	0.052180 (rank : 179)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	106	Target Neighborhood Hits	224	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_HUMAN
NC score	0.052012 (rank : 180)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	106	Target Neighborhood Hits	226	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RFPL3_HUMAN
NC score	0.051175 (rank : 181)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	106	Target Neighborhood Hits	134	Shared Neighborhood Hits	31
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

CM007_HUMAN
NC score	0.050678 (rank : 182)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	106	Target Neighborhood Hits	422	Shared Neighborhood Hits	43
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

TRAF7_MOUSE
NC score	0.048124 (rank : 183)	θ value	5.27518 (rank : 94)
Query Neighborhood Hits	106	Target Neighborhood Hits	470	Shared Neighborhood Hits	58
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

TRAF7_HUMAN
NC score	0.047586 (rank : 184)	θ value	5.27518 (rank : 93)
Query Neighborhood Hits	106	Target Neighborhood Hits	482	Shared Neighborhood Hits	58
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

SNPC2_MOUSE
NC score	0.030396 (rank : 185)	θ value	2.36792 (rank : 78)
Query Neighborhood Hits	106	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q91XA5, Q3UK17, Q8CBS9	Gene names	Snapc2
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 2 (SNAPc subunit 2) (snRNA- activating protein complex 45 kDa subunit) (SNAPc 45 kDa subunit) (Small nuclear RNA-activating complex polypeptide 2).

TSC1_HUMAN
NC score	0.025809 (rank : 186)	θ value	1.06291 (rank : 70)
Query Neighborhood Hits	106	Target Neighborhood Hits	765	Shared Neighborhood Hits	8
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

RL27A_HUMAN
NC score	0.025508 (rank : 187)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	106	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	P46776	Gene names	RPL27A
Domain Architecture
Description	60S ribosomal protein L27a.

BCR_HUMAN
NC score	0.016944 (rank : 188)	θ value	2.36792 (rank : 76)
Query Neighborhood Hits	106	Target Neighborhood Hits	204	Shared Neighborhood Hits	5
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

SSPO_MOUSE
NC score	0.013990 (rank : 189)	θ value	3.0926 (rank : 82)
Query Neighborhood Hits	106	Target Neighborhood Hits	800	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

MUC5B_HUMAN
NC score	0.013272 (rank : 190)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	106	Target Neighborhood Hits	1020	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

F120C_HUMAN
NC score	0.009913 (rank : 191)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	106	Target Neighborhood Hits	91	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NX05	Gene names	FAM120C, CXorf17
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120C (Tumor antigen BJ-HCC-21).

DVL3_MOUSE
NC score	0.009163 (rank : 192)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	106	Target Neighborhood Hits	198	Shared Neighborhood Hits	3
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

SEZ6L_HUMAN
NC score	0.008301 (rank : 193)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	106	Target Neighborhood Hits	289	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

HMCN1_HUMAN
NC score	0.004622 (rank : 194)	θ value	3.0926 (rank : 79)
Query Neighborhood Hits	106	Target Neighborhood Hits	983	Shared Neighborhood Hits	5
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).