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Network neighborhood for query Sequence : BIR1A_MOUSE

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BIR1A_MOUSE
SwissProt Accessions	Q9QWK5, Q9JIB5, Q9R017	Gene names	Birc1a, Naip, Naip1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

BIR1A_MOUSE
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	94	Target Neighborhood Hits	94	Shared Neighborhood Hits	94
SwissProt Accessions	Q9QWK5, Q9JIB5, Q9R017	Gene names	Birc1a, Naip, Naip1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1).

BIR1B_MOUSE
θ value	0 (rank : 2)	NC score	0.995448 (rank : 3)
Query Neighborhood Hits	94	Target Neighborhood Hits	93	Shared Neighborhood Hits	64
SwissProt Accessions	Q9QUK4, O09124, Q9R030	Gene names	Birc1b, Naip-rs6, Naip2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2).

BIR1E_MOUSE
θ value	0 (rank : 3)	NC score	0.996218 (rank : 2)
Query Neighborhood Hits	94	Target Neighborhood Hits	93	Shared Neighborhood Hits	74
SwissProt Accessions	Q9R016, O09121, O09122, P81703, Q9R029	Gene names	Birc1e, Naip-rs3, Naip5
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).

BIR1F_MOUSE
θ value	0 (rank : 4)	NC score	0.995217 (rank : 4)
Query Neighborhood Hits	94	Target Neighborhood Hits	88	Shared Neighborhood Hits	68
SwissProt Accessions	Q9JIB6, O09121, O09122, P81704	Gene names	Birc1f, Naip-rs4, Naip6
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).

BIR1G_MOUSE
θ value	0 (rank : 5)	NC score	0.994757 (rank : 5)
Query Neighborhood Hits	94	Target Neighborhood Hits	92	Shared Neighborhood Hits	68
SwissProt Accessions	Q9JIB3	Gene names	Birc1g, Naip7
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).

BIRC1_HUMAN
θ value	0 (rank : 6)	NC score	0.992756 (rank : 6)
Query Neighborhood Hits	94	Target Neighborhood Hits	61	Shared Neighborhood Hits	41
SwissProt Accessions	Q13075, O75857, Q13730, Q99796	Gene names	BIRC1, NAIP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein).

CAR12_HUMAN
θ value	3.04986e-48 (rank : 7)	NC score	0.759681 (rank : 7)
Query Neighborhood Hits	94	Target Neighborhood Hits	132	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NPP4, Q96J81, Q96J82, Q96J83	Gene names	CARD12, CLAN, CLAN1
Domain Architecture
Description	Caspase recruitment domain-containing protein 12 (Ice protease- activating factor) (Ipaf) (CARD, LRR, and NACHT-containing protein) (Clan protein).

BIRC2_HUMAN
θ value	4.88048e-38 (rank : 8)	NC score	0.704498 (rank : 10)
Query Neighborhood Hits	94	Target Neighborhood Hits	142	Shared Neighborhood Hits	19
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

BIRC4_MOUSE
θ value	4.13158e-37 (rank : 9)	NC score	0.721975 (rank : 8)
Query Neighborhood Hits	94	Target Neighborhood Hits	89	Shared Neighborhood Hits	17
SwissProt Accessions	Q60989, O08865	Gene names	Birc4, Aipa, Api3, Miha, Xiap
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3).

BIRC2_MOUSE
θ value	1.20211e-36 (rank : 10)	NC score	0.700617 (rank : 11)
Query Neighborhood Hits	94	Target Neighborhood Hits	137	Shared Neighborhood Hits	22
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

BIRC3_HUMAN
θ value	2.05049e-36 (rank : 11)	NC score	0.698151 (rank : 12)
Query Neighborhood Hits	94	Target Neighborhood Hits	133	Shared Neighborhood Hits	18
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

BIRC3_MOUSE
θ value	7.79185e-36 (rank : 12)	NC score	0.695606 (rank : 13)
Query Neighborhood Hits	94	Target Neighborhood Hits	113	Shared Neighborhood Hits	17
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

BIRC4_HUMAN
θ value	1.73584e-35 (rank : 13)	NC score	0.715550 (rank : 9)
Query Neighborhood Hits	94	Target Neighborhood Hits	89	Shared Neighborhood Hits	17
SwissProt Accessions	P98170, Q9NQ14	Gene names	BIRC4, API3, IAP3, XIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP).

BIRC7_HUMAN
θ value	7.82807e-20 (rank : 14)	NC score	0.624354 (rank : 15)
Query Neighborhood Hits	94	Target Neighborhood Hits	185	Shared Neighborhood Hits	19
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

BIRC8_HUMAN
θ value	8.95645e-16 (rank : 15)	NC score	0.629293 (rank : 14)
Query Neighborhood Hits	94	Target Neighborhood Hits	121	Shared Neighborhood Hits	17
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

BIRC5_MOUSE
θ value	1.38499e-08 (rank : 16)	NC score	0.620793 (rank : 16)
Query Neighborhood Hits	94	Target Neighborhood Hits	19	Shared Neighborhood Hits	17
SwissProt Accessions	O70201, Q923F7, Q9WU53, Q9WU54	Gene names	Birc5, Api4, Iap4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4) (TIAP).

BIRC5_HUMAN
θ value	2.36244e-08 (rank : 17)	NC score	0.617640 (rank : 17)
Query Neighborhood Hits	94	Target Neighborhood Hits	20	Shared Neighborhood Hits	17
SwissProt Accessions	O15392, Q2I3N8, Q4VGX0, Q53F61, Q5MGC6, Q6FHL2, Q75SP2, Q9P2W8	Gene names	BIRC5, API4, IAP4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4).

NALP1_HUMAN
θ value	8.97725e-08 (rank : 18)	NC score	0.281819 (rank : 22)
Query Neighborhood Hits	94	Target Neighborhood Hits	138	Shared Neighborhood Hits	27
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

CAR15_MOUSE
θ value	3.41135e-07 (rank : 19)	NC score	0.285176 (rank : 21)
Query Neighborhood Hits	94	Target Neighborhood Hits	93	Shared Neighborhood Hits	30
SwissProt Accessions	Q8K3Z0	Gene names	Card15, Nod2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2).

LRC31_HUMAN
θ value	3.41135e-07 (rank : 20)	NC score	0.338971 (rank : 18)
Query Neighborhood Hits	94	Target Neighborhood Hits	139	Shared Neighborhood Hits	29
SwissProt Accessions	Q6UY01, Q8N848, Q9H5N5	Gene names	LRRC31
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 31.

NALP4_HUMAN
θ value	3.41135e-07 (rank : 21)	NC score	0.250926 (rank : 28)
Query Neighborhood Hits	94	Target Neighborhood Hits	81	Shared Neighborhood Hits	28
SwissProt Accessions	Q96MN2, Q86W87, Q96AY6	Gene names	NALP4, PAN2, PYPAF4, RNH2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 4 (PYRIN-containing APAF1-like protein 4) (PAAD and NACHT-containing protein 2) (PYRIN and NACHT- containing protein 2) (Ribonuclease inhibitor 2).

NAL10_MOUSE
θ value	1.69304e-06 (rank : 22)	NC score	0.296275 (rank : 20)
Query Neighborhood Hits	94	Target Neighborhood Hits	46	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CCN1	Gene names	Nalp10, Pynod
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10.

BIRC6_HUMAN
θ value	2.88788e-06 (rank : 23)	NC score	0.324270 (rank : 19)
Query Neighborhood Hits	94	Target Neighborhood Hits	161	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).

NALP2_HUMAN
θ value	2.88788e-06 (rank : 24)	NC score	0.271682 (rank : 23)
Query Neighborhood Hits	94	Target Neighborhood Hits	65	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NX02, Q53FL5, Q59G09, Q8IXT0, Q9BVN5, Q9H6G6, Q9HAV9, Q9NWK3	Gene names	NALP2, NBS1, PAN1, PYPAF2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 2 (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2) (Nucleotide-binding site protein 1).

NAL12_HUMAN
θ value	1.09739e-05 (rank : 25)	NC score	0.238020 (rank : 30)
Query Neighborhood Hits	94	Target Neighborhood Hits	96	Shared Neighborhood Hits	34
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

NAL10_HUMAN
θ value	2.44474e-05 (rank : 26)	NC score	0.269998 (rank : 24)
Query Neighborhood Hits	94	Target Neighborhood Hits	55	Shared Neighborhood Hits	26
SwissProt Accessions	Q86W26, Q6JGT0	Gene names	NALP10, NOD8, PYNOD
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10 (Nucleotide-binding oligomerization domain protein 8).

NALP7_HUMAN
θ value	4.1701e-05 (rank : 27)	NC score	0.259416 (rank : 26)
Query Neighborhood Hits	94	Target Neighborhood Hits	65	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WX94, Q7RTR1	Gene names	NALP7, NOD12, PYPAF3
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 7 (PYRIN-containing APAF1-like protein 3).

NAL14_HUMAN
θ value	9.29e-05 (rank : 28)	NC score	0.225317 (rank : 32)
Query Neighborhood Hits	94	Target Neighborhood Hits	76	Shared Neighborhood Hits	28
SwissProt Accessions	Q86W24, Q7RTR6	Gene names	NALP14, NOD5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 14 (Nucleotide-binding oligomerization domain protein 5).

NALP6_MOUSE
θ value	9.29e-05 (rank : 29)	NC score	0.239591 (rank : 29)
Query Neighborhood Hits	94	Target Neighborhood Hits	55	Shared Neighborhood Hits	26
SwissProt Accessions	Q91WS2, Q8K0L4	Gene names	Nalp6, Pypaf5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5-like).

CIAS1_HUMAN
θ value	0.000121331 (rank : 30)	NC score	0.218889 (rank : 33)
Query Neighborhood Hits	94	Target Neighborhood Hits	76	Shared Neighborhood Hits	32
SwissProt Accessions	Q96P20, O75434, Q59H68, Q5JQS8, Q5JQS9, Q6TG35, Q8TCW0, Q8TEU9, Q8WXH9	Gene names	CIAS1, NALP3, PYPAF1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein (Cryopyrin) (NACHT-, LRR- and PYD-containing protein 3) (PYRIN-containing APAF1-like protein 1) (Angiotensin/vasopressin receptor AII/AVP-like).

CAR15_HUMAN
θ value	0.000602161 (rank : 31)	NC score	0.255118 (rank : 27)
Query Neighborhood Hits	94	Target Neighborhood Hits	77	Shared Neighborhood Hits	30
SwissProt Accessions	Q9HC29, Q96RH5, Q96RH6, Q96RH8	Gene names	CARD15, IBD1, NOD2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2) (Inflammatory bowel disease protein 1).

LRC15_MOUSE
θ value	0.00102713 (rank : 32)	NC score	0.054313 (rank : 67)
Query Neighborhood Hits	94	Target Neighborhood Hits	305	Shared Neighborhood Hits	31
SwissProt Accessions	Q80X72	Gene names	Lrrc15
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 15 precursor.

NAL13_HUMAN
θ value	0.00102713 (rank : 33)	NC score	0.260531 (rank : 25)
Query Neighborhood Hits	94	Target Neighborhood Hits	93	Shared Neighborhood Hits	31
SwissProt Accessions	Q86W25, Q7RTR5	Gene names	NALP13, NOD14
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 13 (Nucleotide-binding oligomerization domain protein 14).

NALP6_HUMAN
θ value	0.00390308 (rank : 34)	NC score	0.232340 (rank : 31)
Query Neighborhood Hits	94	Target Neighborhood Hits	52	Shared Neighborhood Hits	26
SwissProt Accessions	P59044	Gene names	NALP6, PYPAF5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5).

TLR8_MOUSE
θ value	0.0252991 (rank : 35)	NC score	0.042440 (rank : 74)
Query Neighborhood Hits	94	Target Neighborhood Hits	297	Shared Neighborhood Hits	27
SwissProt Accessions	P58682, Q91XI7	Gene names	Tlr8
Domain Architecture
Description	Toll-like receptor 8 precursor.

CIAS1_MOUSE
θ value	0.0330416 (rank : 36)	NC score	0.196961 (rank : 34)
Query Neighborhood Hits	94	Target Neighborhood Hits	67	Shared Neighborhood Hits	30
SwissProt Accessions	Q8R4B8, Q6JEL0	Gene names	Cias1, Mmig1, Nalp3, Pypaf1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein homolog (PYRIN-containing APAF1-like protein 1) (Mast cell maturation-associated-inducible protein 1) (Cryopyrin).

LRC18_MOUSE
θ value	0.0736092 (rank : 37)	NC score	0.061550 (rank : 58)
Query Neighborhood Hits	94	Target Neighborhood Hits	224	Shared Neighborhood Hits	26
SwissProt Accessions	Q9CQ07, Q6P8T8, Q80ZT3, Q9CW01, Q9DA89	Gene names	Lrrc18, Mtlr1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 18 (Testis-specific LRR protein).

LRC18_HUMAN
θ value	0.0961366 (rank : 38)	NC score	0.053508 (rank : 68)
Query Neighborhood Hits	94	Target Neighborhood Hits	217	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N456, Q6UY02	Gene names	LRRC18
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 18.

NALP5_MOUSE
θ value	0.125558 (rank : 39)	NC score	0.154083 (rank : 38)
Query Neighborhood Hits	94	Target Neighborhood Hits	560	Shared Neighborhood Hits	30
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

FBXL7_HUMAN
θ value	0.163984 (rank : 40)	NC score	0.029083 (rank : 83)
Query Neighborhood Hits	94	Target Neighborhood Hits	91	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UJT9, O94926	Gene names	FBXL7, FBL6, FBL7, KIAA0840
Domain Architecture
Description	F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7).

PHLPP_HUMAN
θ value	0.279714 (rank : 41)	NC score	0.033687 (rank : 79)
Query Neighborhood Hits	94	Target Neighborhood Hits	604	Shared Neighborhood Hits	27
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

FLII_HUMAN
θ value	0.365318 (rank : 42)	NC score	0.044680 (rank : 72)
Query Neighborhood Hits	94	Target Neighborhood Hits	318	Shared Neighborhood Hits	31
SwissProt Accessions	Q13045	Gene names	FLII, FLIL
Domain Architecture
Description	Protein flightless-1 homolog.

C2TA_MOUSE
θ value	0.47712 (rank : 43)	NC score	0.162709 (rank : 35)
Query Neighborhood Hits	94	Target Neighborhood Hits	131	Shared Neighborhood Hits	30
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).

LRC47_MOUSE
θ value	0.47712 (rank : 44)	NC score	0.048883 (rank : 70)
Query Neighborhood Hits	94	Target Neighborhood Hits	299	Shared Neighborhood Hits	29
SwissProt Accessions	Q505F5, Q3U380, Q6ZPW2, Q9CUZ0	Gene names	Lrrc47, Kiaa1185
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 47.

GPV_MOUSE
θ value	0.62314 (rank : 45)	NC score	0.033499 (rank : 80)
Query Neighborhood Hits	94	Target Neighborhood Hits	293	Shared Neighborhood Hits	27
SwissProt Accessions	O08742	Gene names	Gp5
Domain Architecture	No domain graphic available
Description	Platelet glycoprotein V precursor (GPV) (CD42D antigen).

LRRC7_MOUSE
θ value	0.62314 (rank : 46)	NC score	0.037037 (rank : 77)
Query Neighborhood Hits	94	Target Neighborhood Hits	416	Shared Neighborhood Hits	27
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRN5_HUMAN
θ value	0.62314 (rank : 47)	NC score	0.022922 (rank : 89)
Query Neighborhood Hits	94	Target Neighborhood Hits	493	Shared Neighborhood Hits	25
SwissProt Accessions	O75325, Q5T0Y0, Q6UXM0, Q8N182	Gene names	LRRN5, GAC1, LRRN2
Domain Architecture
Description	Leucine-rich repeats neuronal protein 5 precursor (Glioma amplified on chromosome 1 protein).

PHLPP_MOUSE
θ value	0.62314 (rank : 48)	NC score	0.032640 (rank : 81)
Query Neighborhood Hits	94	Target Neighborhood Hits	394	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

RB6I2_HUMAN
θ value	0.813845 (rank : 49)	NC score	0.004774 (rank : 105)
Query Neighborhood Hits	94	Target Neighborhood Hits	1584	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

CPN2_HUMAN
θ value	1.06291 (rank : 50)	NC score	0.027530 (rank : 84)
Query Neighborhood Hits	94	Target Neighborhood Hits	279	Shared Neighborhood Hits	24
SwissProt Accessions	P22792, Q86SU4, Q8N5V4	Gene names	CPN2
Domain Architecture	No domain graphic available
Description	Carboxypeptidase N subunit 2 precursor (Carboxypeptidase N polypeptide 2) (Carboxypeptidase N 83 kDa chain) (Carboxypeptidase N regulatory subunit) (Carboxypeptidase N large subunit).

LRRC7_HUMAN
θ value	1.06291 (rank : 51)	NC score	0.035884 (rank : 78)
Query Neighborhood Hits	94	Target Neighborhood Hits	423	Shared Neighborhood Hits	27
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

PXDC2_MOUSE
θ value	1.06291 (rank : 52)	NC score	0.057511 (rank : 65)
Query Neighborhood Hits	94	Target Neighborhood Hits	29	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DC11, Q6PET5, Q91ZV6	Gene names	Plxdc2, Tem7r
Domain Architecture	No domain graphic available
Description	Plexin domain-containing protein 2 precursor (Tumor endothelial marker 7-related protein).

3BP1_MOUSE
θ value	1.38821 (rank : 53)	NC score	0.024193 (rank : 88)
Query Neighborhood Hits	94	Target Neighborhood Hits	238	Shared Neighborhood Hits	6
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

OL494_MOUSE
θ value	1.38821 (rank : 54)	NC score	0.006044 (rank : 103)
Query Neighborhood Hits	94	Target Neighborhood Hits	689	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VG07	Gene names	Olfr494, Mor204-10
Domain Architecture
Description	Olfactory receptor 494 (Olfactory receptor 204-10).

SHOC2_HUMAN
θ value	1.38821 (rank : 55)	NC score	0.039313 (rank : 76)
Query Neighborhood Hits	94	Target Neighborhood Hits	330	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UQ13, O76063	Gene names	SHOC2, KIAA0862
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat protein SHOC-2 (Ras-binding protein Sur-8).

SHOC2_MOUSE
θ value	1.38821 (rank : 56)	NC score	0.042249 (rank : 75)
Query Neighborhood Hits	94	Target Neighborhood Hits	308	Shared Neighborhood Hits	28
SwissProt Accessions	O88520, Q3UJH6, Q8BVL0	Gene names	Shoc2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat protein SHOC-2 (Ras-binding protein Sur-8).

CPSM_MOUSE
θ value	1.81305 (rank : 57)	NC score	0.012070 (rank : 95)
Query Neighborhood Hits	94	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C196, Q6NX75	Gene names	Cps1
Domain Architecture	No domain graphic available
Description	Carbamoyl-phosphate synthase [ammonia], mitochondrial precursor (EC 6.3.4.16) (Carbamoyl-phosphate synthetase I) (CPSase I).

PXDC2_HUMAN
θ value	1.81305 (rank : 58)	NC score	0.050655 (rank : 69)
Query Neighborhood Hits	94	Target Neighborhood Hits	29	Shared Neighborhood Hits	7
SwissProt Accessions	Q6UX71, Q96E59, Q96PD9, Q96SU9	Gene names	PLXDC2, TEM7R
Domain Architecture	No domain graphic available
Description	Plexin domain-containing protein 2 precursor (Tumor endothelial marker 7-related protein).

EP15_MOUSE
θ value	2.36792 (rank : 59)	NC score	0.003856 (rank : 111)
Query Neighborhood Hits	94	Target Neighborhood Hits	820	Shared Neighborhood Hits	5
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

OL498_MOUSE
θ value	2.36792 (rank : 60)	NC score	0.008299 (rank : 98)
Query Neighborhood Hits	94	Target Neighborhood Hits	642	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VEW2	Gene names	Olfr498, Mor204-36
Domain Architecture
Description	Olfactory receptor 498 (Olfactory receptor 204-36).

PLK1_MOUSE
θ value	2.36792 (rank : 61)	NC score	-0.001685 (rank : 118)
Query Neighborhood Hits	94	Target Neighborhood Hits	849	Shared Neighborhood Hits	3
SwissProt Accessions	Q07832	Gene names	Plk1, Plk
Domain Architecture
Description	Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13).

SIX2_HUMAN
θ value	2.36792 (rank : 62)	NC score	0.025566 (rank : 86)
Query Neighborhood Hits	94	Target Neighborhood Hits	345	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NPC8, Q9BXH7	Gene names	SIX2
Domain Architecture
Description	Homeobox protein SIX2 (Sine oculis homeobox homolog 2).

SIX2_MOUSE
θ value	2.36792 (rank : 63)	NC score	0.025200 (rank : 87)
Query Neighborhood Hits	94	Target Neighborhood Hits	376	Shared Neighborhood Hits	8
SwissProt Accessions	Q62232, P70179	Gene names	Six2
Domain Architecture
Description	Homeobox protein SIX2 (Sine oculis homeobox homolog 2).

OL497_MOUSE
θ value	3.0926 (rank : 64)	NC score	0.004868 (rank : 104)
Query Neighborhood Hits	94	Target Neighborhood Hits	687	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VG08	Gene names	Olfr497, Mor204-9
Domain Architecture
Description	Olfactory receptor 497 (Olfactory receptor 204-9).

OL510_MOUSE
θ value	3.0926 (rank : 65)	NC score	0.004176 (rank : 109)
Query Neighborhood Hits	94	Target Neighborhood Hits	681	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VEW6	Gene names	Olfr510, Mor204-34
Domain Architecture
Description	Olfactory receptor 510 (Olfactory receptor 204-34).

PLK1_HUMAN
θ value	3.0926 (rank : 66)	NC score	-0.001861 (rank : 119)
Query Neighborhood Hits	94	Target Neighborhood Hits	849	Shared Neighborhood Hits	3
SwissProt Accessions	P53350, Q15153, Q99746	Gene names	PLK1, PLK
Domain Architecture
Description	Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13).

TLR9_MOUSE
θ value	3.0926 (rank : 67)	NC score	0.048076 (rank : 71)
Query Neighborhood Hits	94	Target Neighborhood Hits	291	Shared Neighborhood Hits	31
SwissProt Accessions	Q9EQU3, Q99MF2, Q99MQ8	Gene names	Tlr9
Domain Architecture
Description	Toll-like receptor 9 precursor (CD289 antigen).

TRIM2_HUMAN
θ value	3.0926 (rank : 68)	NC score	0.009349 (rank : 97)
Query Neighborhood Hits	94	Target Neighborhood Hits	330	Shared Neighborhood Hits	7
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
θ value	3.0926 (rank : 69)	NC score	0.009384 (rank : 96)
Query Neighborhood Hits	94	Target Neighborhood Hits	331	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

LRC47_HUMAN
θ value	4.03905 (rank : 70)	NC score	0.042451 (rank : 73)
Query Neighborhood Hits	94	Target Neighborhood Hits	300	Shared Neighborhood Hits	29
SwissProt Accessions	Q8N1G4, Q9ULN5	Gene names	LRRC47, KIAA1185
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 47.

MX1_MOUSE
θ value	4.03905 (rank : 71)	NC score	0.006456 (rank : 102)
Query Neighborhood Hits	94	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	P09922	Gene names	Mx1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Influenza resistance protein).

OL495_MOUSE
θ value	4.03905 (rank : 72)	NC score	0.004688 (rank : 107)
Query Neighborhood Hits	94	Target Neighborhood Hits	666	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VF12	Gene names	Olfr495, Mor204-37
Domain Architecture
Description	Olfactory receptor 495 (Olfactory receptor 204-37).

RB6I2_MOUSE
θ value	4.03905 (rank : 73)	NC score	0.003738 (rank : 112)
Query Neighborhood Hits	94	Target Neighborhood Hits	1433	Shared Neighborhood Hits	10
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

CARD4_MOUSE
θ value	5.27518 (rank : 74)	NC score	0.162669 (rank : 36)
Query Neighborhood Hits	94	Target Neighborhood Hits	85	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BHB0, Q8BUT6	Gene names	Card4
Domain Architecture
Description	Caspase recruitment domain-containing protein 4.

NCOA2_HUMAN
θ value	5.27518 (rank : 75)	NC score	0.016326 (rank : 94)
Query Neighborhood Hits	94	Target Neighborhood Hits	281	Shared Neighborhood Hits	4
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

OL490_MOUSE
θ value	5.27518 (rank : 76)	NC score	0.002043 (rank : 115)
Query Neighborhood Hits	94	Target Neighborhood Hits	691	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VFD2	Gene names	Olfr490, Mor204-17
Domain Architecture
Description	Olfactory receptor 490 (Olfactory receptor 204-17).

OL493_MOUSE
θ value	5.27518 (rank : 77)	NC score	0.004120 (rank : 110)
Query Neighborhood Hits	94	Target Neighborhood Hits	658	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VEW5	Gene names	Olfr493, Mor204-35
Domain Architecture
Description	Olfactory receptor 493 (Olfactory receptor 204-35).

OL507_MOUSE
θ value	5.27518 (rank : 78)	NC score	0.004256 (rank : 108)
Query Neighborhood Hits	94	Target Neighborhood Hits	635	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VG13	Gene names	Olfr507, Mor204-7
Domain Architecture
Description	Olfactory receptor 507 (Olfactory receptor 204-7).

SIX1_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.020012 (rank : 91)
Query Neighborhood Hits	94	Target Neighborhood Hits	343	Shared Neighborhood Hits	8
SwissProt Accessions	Q15475, Q96H64	Gene names	SIX1
Domain Architecture
Description	Homeobox protein SIX1 (Sine oculis homeobox homolog 1).

SIX1_MOUSE
θ value	5.27518 (rank : 80)	NC score	0.019999 (rank : 92)
Query Neighborhood Hits	94	Target Neighborhood Hits	341	Shared Neighborhood Hits	8
SwissProt Accessions	Q62231, Q8CIL7	Gene names	Six1
Domain Architecture
Description	Homeobox protein SIX1 (Sine oculis homeobox homolog 1).

FLRT1_HUMAN
θ value	6.88961 (rank : 81)	NC score	0.017403 (rank : 93)
Query Neighborhood Hits	94	Target Neighborhood Hits	286	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NZU1	Gene names	FLRT1
Domain Architecture
Description	Leucine-rich repeat transmembrane protein FLRT1 precursor (Fibronectin-like domain-containing leucine-rich transmembrane protein 1).

HDAC5_MOUSE
θ value	6.88961 (rank : 82)	NC score	0.003210 (rank : 114)
Query Neighborhood Hits	94	Target Neighborhood Hits	310	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2V6, Q9JL73	Gene names	Hdac5
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Histone deacetylase mHDA1).

LRC8D_MOUSE
θ value	6.88961 (rank : 83)	NC score	0.030361 (rank : 82)
Query Neighborhood Hits	94	Target Neighborhood Hits	284	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BGR2, Q3UVA9, Q8CI13	Gene names	Lrrc8d, Lrrc5
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8D.

LSHR_MOUSE
θ value	6.88961 (rank : 84)	NC score	0.006776 (rank : 101)
Query Neighborhood Hits	94	Target Neighborhood Hits	686	Shared Neighborhood Hits	14
SwissProt Accessions	P30730	Gene names	Lhcgr, Lhr
Domain Architecture
Description	Lutropin-choriogonadotropic hormone receptor precursor (LH/CG-R) (LSH- R) (Luteinizing hormone receptor).

NALP5_HUMAN
θ value	6.88961 (rank : 85)	NC score	0.158046 (rank : 37)
Query Neighborhood Hits	94	Target Neighborhood Hits	88	Shared Neighborhood Hits	29
SwissProt Accessions	P59047, Q86W29	Gene names	NALP5, MATER
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Mater protein homolog).

OL486_MOUSE
θ value	6.88961 (rank : 86)	NC score	0.004766 (rank : 106)
Query Neighborhood Hits	94	Target Neighborhood Hits	650	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VFD0	Gene names	Olfr486, Mor204-19
Domain Architecture
Description	Olfactory receptor 486 (Olfactory receptor 204-19).

SPAG5_MOUSE
θ value	6.88961 (rank : 87)	NC score	0.003563 (rank : 113)
Query Neighborhood Hits	94	Target Neighborhood Hits	612	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

ABCF3_HUMAN
θ value	8.99809 (rank : 88)	NC score	0.007458 (rank : 99)
Query Neighborhood Hits	94	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NUQ8, Q86UA2, Q8NAN1, Q96GS8, Q9H7A8	Gene names	ABCF3
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 3.

ABCF3_MOUSE
θ value	8.99809 (rank : 89)	NC score	0.007256 (rank : 100)
Query Neighborhood Hits	94	Target Neighborhood Hits	126	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K268, Q9JL49	Gene names	Abcf3
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 3.

BAZ1A_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.001495 (rank : 117)
Query Neighborhood Hits	94	Target Neighborhood Hits	693	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

CD180_MOUSE
θ value	8.99809 (rank : 91)	NC score	0.021362 (rank : 90)
Query Neighborhood Hits	94	Target Neighborhood Hits	283	Shared Neighborhood Hits	26
SwissProt Accessions	Q62192	Gene names	Cd180, Ly78, Rp105
Domain Architecture
Description	CD180 antigen precursor (Lymphocyte antigen 78) (Radioprotective 105 kDa protein).

IF31_HUMAN
θ value	8.99809 (rank : 92)	NC score	0.027001 (rank : 85)
Query Neighborhood Hits	94	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	O75822, Q9BUD2, Q9H8Q2, Q9UI65	Gene names	EIF3S1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 1 (eIF-3 alpha) (eIF3 p35) (eIF3j).

LRRC1_MOUSE
θ value	8.99809 (rank : 93)	NC score	0.058316 (rank : 64)
Query Neighborhood Hits	94	Target Neighborhood Hits	281	Shared Neighborhood Hits	29
SwissProt Accessions	Q80VQ1, Q3UI50, Q8BKR1, Q8BUS9	Gene names	Lrrc1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1.

OL482_MOUSE
θ value	8.99809 (rank : 94)	NC score	0.001713 (rank : 116)
Query Neighborhood Hits	94	Target Neighborhood Hits	662	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VG03	Gene names	Olfr482, Mor204-14
Domain Architecture
Description	Olfactory receptor 482 (Olfactory receptor 204-14).

ASC_MOUSE
θ value	θ > 10 (rank : 95)	NC score	0.054705 (rank : 66)
Query Neighborhood Hits	94	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	Q9EPB4, Q9D2W9	Gene names	Pycard, Asc
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein).

C2TA_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.103477 (rank : 48)
Query Neighborhood Hits	94	Target Neighborhood Hits	190	Shared Neighborhood Hits	23
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

CARD4_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.140989 (rank : 40)
Query Neighborhood Hits	94	Target Neighborhood Hits	102	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y239, Q8IWF5	Gene names	CARD4, NOD1
Domain Architecture
Description	Caspase recruitment domain-containing protein 4 (Protein Nod1).

CARD8_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.059096 (rank : 61)
Query Neighborhood Hits	94	Target Neighborhood Hits	22	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2G2, Q6PGP8, Q96P82	Gene names	CARD8, KIAA0955, NDPP1
Domain Architecture
Description	Caspase recruitment domain-containing protein 8 (Apoptotic protein NDPP1) (DACAR) (CARD-inhibitor of NF-kappa-B-activating ligand) (CARDINAL) (Tumor-up-regulated CARD-containing antagonist of CASP9) (TUCAN).

CF154_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.059617 (rank : 60)
Query Neighborhood Hits	94	Target Neighborhood Hits	36	Shared Neighborhood Hits	17
SwissProt Accessions	Q5JTD7	Gene names	C6orf154
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf154.

CGRF1_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.076785 (rank : 51)
Query Neighborhood Hits	94	Target Neighborhood Hits	51	Shared Neighborhood Hits	10
SwissProt Accessions	Q99675, Q96BX2	Gene names	CGRRF1, CGR19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

CGRF1_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.074440 (rank : 52)
Query Neighborhood Hits	94	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BMJ7, Q3U3F1, Q8CI24	Gene names	Cgrrf1, Cgr19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

LRC34_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.072518 (rank : 53)
Query Neighborhood Hits	94	Target Neighborhood Hits	67	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IZ02	Gene names	LRRC34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

LRC34_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.064578 (rank : 56)
Query Neighborhood Hits	94	Target Neighborhood Hits	58	Shared Neighborhood Hits	17
SwissProt Accessions	Q9DAM1	Gene names	Lrrc34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

LRRC1_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.058701 (rank : 62)
Query Neighborhood Hits	94	Target Neighborhood Hits	282	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BTT6, Q9HAC0, Q9NVF1	Gene names	LRRC1, LANO
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1 (LAP and no PDZ protein) (LANO adapter protein).

LRSM1_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.058677 (rank : 63)
Query Neighborhood Hits	94	Target Neighborhood Hits	1078	Shared Neighborhood Hits	36
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

LRSM1_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.067653 (rank : 54)
Query Neighborhood Hits	94	Target Neighborhood Hits	874	Shared Neighborhood Hits	35
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

MYLIP_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.081091 (rank : 50)
Query Neighborhood Hits	94	Target Neighborhood Hits	162	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

MYLIP_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.067369 (rank : 55)
Query Neighborhood Hits	94	Target Neighborhood Hits	139	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

NAL11_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.141514 (rank : 39)
Query Neighborhood Hits	94	Target Neighborhood Hits	66	Shared Neighborhood Hits	23
SwissProt Accessions	P59045, Q53ZZ0, Q8NBF5	Gene names	NALP11, NOD17, PYPAF6
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 11 (PYRIN-containing APAF1-like protein 6) (Nucleotide-binding oligomerization domain protein 17).

NEUL1_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.061484 (rank : 59)
Query Neighborhood Hits	94	Target Neighborhood Hits	114	Shared Neighborhood Hits	8
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

NEURL_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.063627 (rank : 57)
Query Neighborhood Hits	94	Target Neighborhood Hits	106	Shared Neighborhood Hits	8
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

RFFL_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.110027 (rank : 46)
Query Neighborhood Hits	94	Target Neighborhood Hits	175	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RFFL_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.111915 (rank : 44)
Query Neighborhood Hits	94	Target Neighborhood Hits	145	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

RINI_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.125545 (rank : 41)
Query Neighborhood Hits	94	Target Neighborhood Hits	78	Shared Neighborhood Hits	23
SwissProt Accessions	P13489	Gene names	RNH1, PRI, RNH
Domain Architecture
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1) (RAI) (Placental ribonuclease inhibitor) (RNase inhibitor) (RI).

RINI_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.122638 (rank : 43)
Query Neighborhood Hits	94	Target Neighborhood Hits	87	Shared Neighborhood Hits	23
SwissProt Accessions	Q91VI7, Q924P4	Gene names	Rnh1, Rnh
Domain Architecture	No domain graphic available
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1).

RKHD1_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.084046 (rank : 49)
Query Neighborhood Hits	94	Target Neighborhood Hits	163	Shared Neighborhood Hits	8
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

RNF26_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.124760 (rank : 42)
Query Neighborhood Hits	94	Target Neighborhood Hits	95	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

RNF34_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.109875 (rank : 47)
Query Neighborhood Hits	94	Target Neighborhood Hits	153	Shared Neighborhood Hits	8
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RNF34_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.110397 (rank : 45)
Query Neighborhood Hits	94	Target Neighborhood Hits	160	Shared Neighborhood Hits	8
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

Hits sorted by NC score

BIR1A_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	94	Target Neighborhood Hits	94	Shared Neighborhood Hits	94
SwissProt Accessions	Q9QWK5, Q9JIB5, Q9R017	Gene names	Birc1a, Naip, Naip1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1).

BIR1E_MOUSE
NC score	0.996218 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	94	Target Neighborhood Hits	93	Shared Neighborhood Hits	74
SwissProt Accessions	Q9R016, O09121, O09122, P81703, Q9R029	Gene names	Birc1e, Naip-rs3, Naip5
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).

BIR1B_MOUSE
NC score	0.995448 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	94	Target Neighborhood Hits	93	Shared Neighborhood Hits	64
SwissProt Accessions	Q9QUK4, O09124, Q9R030	Gene names	Birc1b, Naip-rs6, Naip2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2).

BIR1F_MOUSE
NC score	0.995217 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	94	Target Neighborhood Hits	88	Shared Neighborhood Hits	68
SwissProt Accessions	Q9JIB6, O09121, O09122, P81704	Gene names	Birc1f, Naip-rs4, Naip6
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).

BIR1G_MOUSE
NC score	0.994757 (rank : 5)	θ value	0 (rank : 5)
Query Neighborhood Hits	94	Target Neighborhood Hits	92	Shared Neighborhood Hits	68
SwissProt Accessions	Q9JIB3	Gene names	Birc1g, Naip7
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).

BIRC1_HUMAN
NC score	0.992756 (rank : 6)	θ value	0 (rank : 6)
Query Neighborhood Hits	94	Target Neighborhood Hits	61	Shared Neighborhood Hits	41
SwissProt Accessions	Q13075, O75857, Q13730, Q99796	Gene names	BIRC1, NAIP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein).

CAR12_HUMAN
NC score	0.759681 (rank : 7)	θ value	3.04986e-48 (rank : 7)
Query Neighborhood Hits	94	Target Neighborhood Hits	132	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NPP4, Q96J81, Q96J82, Q96J83	Gene names	CARD12, CLAN, CLAN1
Domain Architecture
Description	Caspase recruitment domain-containing protein 12 (Ice protease- activating factor) (Ipaf) (CARD, LRR, and NACHT-containing protein) (Clan protein).

BIRC4_MOUSE
NC score	0.721975 (rank : 8)	θ value	4.13158e-37 (rank : 9)
Query Neighborhood Hits	94	Target Neighborhood Hits	89	Shared Neighborhood Hits	17
SwissProt Accessions	Q60989, O08865	Gene names	Birc4, Aipa, Api3, Miha, Xiap
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3).

BIRC4_HUMAN
NC score	0.715550 (rank : 9)	θ value	1.73584e-35 (rank : 13)
Query Neighborhood Hits	94	Target Neighborhood Hits	89	Shared Neighborhood Hits	17
SwissProt Accessions	P98170, Q9NQ14	Gene names	BIRC4, API3, IAP3, XIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP).

BIRC2_HUMAN
NC score	0.704498 (rank : 10)	θ value	4.88048e-38 (rank : 8)
Query Neighborhood Hits	94	Target Neighborhood Hits	142	Shared Neighborhood Hits	19
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

BIRC2_MOUSE
NC score	0.700617 (rank : 11)	θ value	1.20211e-36 (rank : 10)
Query Neighborhood Hits	94	Target Neighborhood Hits	137	Shared Neighborhood Hits	22
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

BIRC3_HUMAN
NC score	0.698151 (rank : 12)	θ value	2.05049e-36 (rank : 11)
Query Neighborhood Hits	94	Target Neighborhood Hits	133	Shared Neighborhood Hits	18
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

BIRC3_MOUSE
NC score	0.695606 (rank : 13)	θ value	7.79185e-36 (rank : 12)
Query Neighborhood Hits	94	Target Neighborhood Hits	113	Shared Neighborhood Hits	17
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

BIRC8_HUMAN
NC score	0.629293 (rank : 14)	θ value	8.95645e-16 (rank : 15)
Query Neighborhood Hits	94	Target Neighborhood Hits	121	Shared Neighborhood Hits	17
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

BIRC7_HUMAN
NC score	0.624354 (rank : 15)	θ value	7.82807e-20 (rank : 14)
Query Neighborhood Hits	94	Target Neighborhood Hits	185	Shared Neighborhood Hits	19
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

BIRC5_MOUSE
NC score	0.620793 (rank : 16)	θ value	1.38499e-08 (rank : 16)
Query Neighborhood Hits	94	Target Neighborhood Hits	19	Shared Neighborhood Hits	17
SwissProt Accessions	O70201, Q923F7, Q9WU53, Q9WU54	Gene names	Birc5, Api4, Iap4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4) (TIAP).

BIRC5_HUMAN
NC score	0.617640 (rank : 17)	θ value	2.36244e-08 (rank : 17)
Query Neighborhood Hits	94	Target Neighborhood Hits	20	Shared Neighborhood Hits	17
SwissProt Accessions	O15392, Q2I3N8, Q4VGX0, Q53F61, Q5MGC6, Q6FHL2, Q75SP2, Q9P2W8	Gene names	BIRC5, API4, IAP4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4).

LRC31_HUMAN
NC score	0.338971 (rank : 18)	θ value	3.41135e-07 (rank : 20)
Query Neighborhood Hits	94	Target Neighborhood Hits	139	Shared Neighborhood Hits	29
SwissProt Accessions	Q6UY01, Q8N848, Q9H5N5	Gene names	LRRC31
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 31.

BIRC6_HUMAN
NC score	0.324270 (rank : 19)	θ value	2.88788e-06 (rank : 23)
Query Neighborhood Hits	94	Target Neighborhood Hits	161	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).

NAL10_MOUSE
NC score	0.296275 (rank : 20)	θ value	1.69304e-06 (rank : 22)
Query Neighborhood Hits	94	Target Neighborhood Hits	46	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CCN1	Gene names	Nalp10, Pynod
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10.

CAR15_MOUSE
NC score	0.285176 (rank : 21)	θ value	3.41135e-07 (rank : 19)
Query Neighborhood Hits	94	Target Neighborhood Hits	93	Shared Neighborhood Hits	30
SwissProt Accessions	Q8K3Z0	Gene names	Card15, Nod2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2).

NALP1_HUMAN
NC score	0.281819 (rank : 22)	θ value	8.97725e-08 (rank : 18)
Query Neighborhood Hits	94	Target Neighborhood Hits	138	Shared Neighborhood Hits	27
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

NALP2_HUMAN
NC score	0.271682 (rank : 23)	θ value	2.88788e-06 (rank : 24)
Query Neighborhood Hits	94	Target Neighborhood Hits	65	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NX02, Q53FL5, Q59G09, Q8IXT0, Q9BVN5, Q9H6G6, Q9HAV9, Q9NWK3	Gene names	NALP2, NBS1, PAN1, PYPAF2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 2 (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2) (Nucleotide-binding site protein 1).

NAL10_HUMAN
NC score	0.269998 (rank : 24)	θ value	2.44474e-05 (rank : 26)
Query Neighborhood Hits	94	Target Neighborhood Hits	55	Shared Neighborhood Hits	26
SwissProt Accessions	Q86W26, Q6JGT0	Gene names	NALP10, NOD8, PYNOD
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10 (Nucleotide-binding oligomerization domain protein 8).

NAL13_HUMAN
NC score	0.260531 (rank : 25)	θ value	0.00102713 (rank : 33)
Query Neighborhood Hits	94	Target Neighborhood Hits	93	Shared Neighborhood Hits	31
SwissProt Accessions	Q86W25, Q7RTR5	Gene names	NALP13, NOD14
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 13 (Nucleotide-binding oligomerization domain protein 14).

NALP7_HUMAN
NC score	0.259416 (rank : 26)	θ value	4.1701e-05 (rank : 27)
Query Neighborhood Hits	94	Target Neighborhood Hits	65	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WX94, Q7RTR1	Gene names	NALP7, NOD12, PYPAF3
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 7 (PYRIN-containing APAF1-like protein 3).

CAR15_HUMAN
NC score	0.255118 (rank : 27)	θ value	0.000602161 (rank : 31)
Query Neighborhood Hits	94	Target Neighborhood Hits	77	Shared Neighborhood Hits	30
SwissProt Accessions	Q9HC29, Q96RH5, Q96RH6, Q96RH8	Gene names	CARD15, IBD1, NOD2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2) (Inflammatory bowel disease protein 1).

NALP4_HUMAN
NC score	0.250926 (rank : 28)	θ value	3.41135e-07 (rank : 21)
Query Neighborhood Hits	94	Target Neighborhood Hits	81	Shared Neighborhood Hits	28
SwissProt Accessions	Q96MN2, Q86W87, Q96AY6	Gene names	NALP4, PAN2, PYPAF4, RNH2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 4 (PYRIN-containing APAF1-like protein 4) (PAAD and NACHT-containing protein 2) (PYRIN and NACHT- containing protein 2) (Ribonuclease inhibitor 2).

NALP6_MOUSE
NC score	0.239591 (rank : 29)	θ value	9.29e-05 (rank : 29)
Query Neighborhood Hits	94	Target Neighborhood Hits	55	Shared Neighborhood Hits	26
SwissProt Accessions	Q91WS2, Q8K0L4	Gene names	Nalp6, Pypaf5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5-like).

NAL12_HUMAN
NC score	0.238020 (rank : 30)	θ value	1.09739e-05 (rank : 25)
Query Neighborhood Hits	94	Target Neighborhood Hits	96	Shared Neighborhood Hits	34
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

NALP6_HUMAN
NC score	0.232340 (rank : 31)	θ value	0.00390308 (rank : 34)
Query Neighborhood Hits	94	Target Neighborhood Hits	52	Shared Neighborhood Hits	26
SwissProt Accessions	P59044	Gene names	NALP6, PYPAF5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5).

NAL14_HUMAN
NC score	0.225317 (rank : 32)	θ value	9.29e-05 (rank : 28)
Query Neighborhood Hits	94	Target Neighborhood Hits	76	Shared Neighborhood Hits	28
SwissProt Accessions	Q86W24, Q7RTR6	Gene names	NALP14, NOD5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 14 (Nucleotide-binding oligomerization domain protein 5).

CIAS1_HUMAN
NC score	0.218889 (rank : 33)	θ value	0.000121331 (rank : 30)
Query Neighborhood Hits	94	Target Neighborhood Hits	76	Shared Neighborhood Hits	32
SwissProt Accessions	Q96P20, O75434, Q59H68, Q5JQS8, Q5JQS9, Q6TG35, Q8TCW0, Q8TEU9, Q8WXH9	Gene names	CIAS1, NALP3, PYPAF1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein (Cryopyrin) (NACHT-, LRR- and PYD-containing protein 3) (PYRIN-containing APAF1-like protein 1) (Angiotensin/vasopressin receptor AII/AVP-like).

CIAS1_MOUSE
NC score	0.196961 (rank : 34)	θ value	0.0330416 (rank : 36)
Query Neighborhood Hits	94	Target Neighborhood Hits	67	Shared Neighborhood Hits	30
SwissProt Accessions	Q8R4B8, Q6JEL0	Gene names	Cias1, Mmig1, Nalp3, Pypaf1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein homolog (PYRIN-containing APAF1-like protein 1) (Mast cell maturation-associated-inducible protein 1) (Cryopyrin).

C2TA_MOUSE
NC score	0.162709 (rank : 35)	θ value	0.47712 (rank : 43)
Query Neighborhood Hits	94	Target Neighborhood Hits	131	Shared Neighborhood Hits	30
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).

CARD4_MOUSE
NC score	0.162669 (rank : 36)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	94	Target Neighborhood Hits	85	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BHB0, Q8BUT6	Gene names	Card4
Domain Architecture
Description	Caspase recruitment domain-containing protein 4.

NALP5_HUMAN
NC score	0.158046 (rank : 37)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	94	Target Neighborhood Hits	88	Shared Neighborhood Hits	29
SwissProt Accessions	P59047, Q86W29	Gene names	NALP5, MATER
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Mater protein homolog).

NALP5_MOUSE
NC score	0.154083 (rank : 38)	θ value	0.125558 (rank : 39)
Query Neighborhood Hits	94	Target Neighborhood Hits	560	Shared Neighborhood Hits	30
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

NAL11_HUMAN
NC score	0.141514 (rank : 39)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	94	Target Neighborhood Hits	66	Shared Neighborhood Hits	23
SwissProt Accessions	P59045, Q53ZZ0, Q8NBF5	Gene names	NALP11, NOD17, PYPAF6
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 11 (PYRIN-containing APAF1-like protein 6) (Nucleotide-binding oligomerization domain protein 17).

CARD4_HUMAN
NC score	0.140989 (rank : 40)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	94	Target Neighborhood Hits	102	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y239, Q8IWF5	Gene names	CARD4, NOD1
Domain Architecture
Description	Caspase recruitment domain-containing protein 4 (Protein Nod1).

RINI_HUMAN
NC score	0.125545 (rank : 41)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	94	Target Neighborhood Hits	78	Shared Neighborhood Hits	23
SwissProt Accessions	P13489	Gene names	RNH1, PRI, RNH
Domain Architecture
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1) (RAI) (Placental ribonuclease inhibitor) (RNase inhibitor) (RI).

RNF26_HUMAN
NC score	0.124760 (rank : 42)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	94	Target Neighborhood Hits	95	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

RINI_MOUSE
NC score	0.122638 (rank : 43)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	94	Target Neighborhood Hits	87	Shared Neighborhood Hits	23
SwissProt Accessions	Q91VI7, Q924P4	Gene names	Rnh1, Rnh
Domain Architecture	No domain graphic available
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1).

RFFL_MOUSE
NC score	0.111915 (rank : 44)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	94	Target Neighborhood Hits	145	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

RNF34_MOUSE
NC score	0.110397 (rank : 45)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	94	Target Neighborhood Hits	160	Shared Neighborhood Hits	8
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

RFFL_HUMAN
NC score	0.110027 (rank : 46)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	94	Target Neighborhood Hits	175	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RNF34_HUMAN
NC score	0.109875 (rank : 47)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	94	Target Neighborhood Hits	153	Shared Neighborhood Hits	8
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

C2TA_HUMAN
NC score	0.103477 (rank : 48)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	94	Target Neighborhood Hits	190	Shared Neighborhood Hits	23
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

RKHD1_HUMAN
NC score	0.084046 (rank : 49)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	94	Target Neighborhood Hits	163	Shared Neighborhood Hits	8
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

MYLIP_HUMAN
NC score	0.081091 (rank : 50)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	94	Target Neighborhood Hits	162	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

CGRF1_HUMAN
NC score	0.076785 (rank : 51)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	94	Target Neighborhood Hits	51	Shared Neighborhood Hits	10
SwissProt Accessions	Q99675, Q96BX2	Gene names	CGRRF1, CGR19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

CGRF1_MOUSE
NC score	0.074440 (rank : 52)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	94	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BMJ7, Q3U3F1, Q8CI24	Gene names	Cgrrf1, Cgr19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

LRC34_HUMAN
NC score	0.072518 (rank : 53)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	94	Target Neighborhood Hits	67	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IZ02	Gene names	LRRC34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

LRSM1_MOUSE
NC score	0.067653 (rank : 54)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	94	Target Neighborhood Hits	874	Shared Neighborhood Hits	35
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

MYLIP_MOUSE
NC score	0.067369 (rank : 55)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	94	Target Neighborhood Hits	139	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

LRC34_MOUSE
NC score	0.064578 (rank : 56)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	94	Target Neighborhood Hits	58	Shared Neighborhood Hits	17
SwissProt Accessions	Q9DAM1	Gene names	Lrrc34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

NEURL_MOUSE
NC score	0.063627 (rank : 57)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	94	Target Neighborhood Hits	106	Shared Neighborhood Hits	8
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

LRC18_MOUSE
NC score	0.061550 (rank : 58)	θ value	0.0736092 (rank : 37)
Query Neighborhood Hits	94	Target Neighborhood Hits	224	Shared Neighborhood Hits	26
SwissProt Accessions	Q9CQ07, Q6P8T8, Q80ZT3, Q9CW01, Q9DA89	Gene names	Lrrc18, Mtlr1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 18 (Testis-specific LRR protein).

NEUL1_HUMAN
NC score	0.061484 (rank : 59)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	94	Target Neighborhood Hits	114	Shared Neighborhood Hits	8
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

CF154_HUMAN
NC score	0.059617 (rank : 60)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	94	Target Neighborhood Hits	36	Shared Neighborhood Hits	17
SwissProt Accessions	Q5JTD7	Gene names	C6orf154
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf154.

CARD8_HUMAN
NC score	0.059096 (rank : 61)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	94	Target Neighborhood Hits	22	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2G2, Q6PGP8, Q96P82	Gene names	CARD8, KIAA0955, NDPP1
Domain Architecture
Description	Caspase recruitment domain-containing protein 8 (Apoptotic protein NDPP1) (DACAR) (CARD-inhibitor of NF-kappa-B-activating ligand) (CARDINAL) (Tumor-up-regulated CARD-containing antagonist of CASP9) (TUCAN).

LRRC1_HUMAN
NC score	0.058701 (rank : 62)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	94	Target Neighborhood Hits	282	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BTT6, Q9HAC0, Q9NVF1	Gene names	LRRC1, LANO
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1 (LAP and no PDZ protein) (LANO adapter protein).

LRSM1_HUMAN
NC score	0.058677 (rank : 63)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	94	Target Neighborhood Hits	1078	Shared Neighborhood Hits	36
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

LRRC1_MOUSE
NC score	0.058316 (rank : 64)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	94	Target Neighborhood Hits	281	Shared Neighborhood Hits	29
SwissProt Accessions	Q80VQ1, Q3UI50, Q8BKR1, Q8BUS9	Gene names	Lrrc1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1.

PXDC2_MOUSE
NC score	0.057511 (rank : 65)	θ value	1.06291 (rank : 52)
Query Neighborhood Hits	94	Target Neighborhood Hits	29	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DC11, Q6PET5, Q91ZV6	Gene names	Plxdc2, Tem7r
Domain Architecture	No domain graphic available
Description	Plexin domain-containing protein 2 precursor (Tumor endothelial marker 7-related protein).

ASC_MOUSE
NC score	0.054705 (rank : 66)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	94	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	Q9EPB4, Q9D2W9	Gene names	Pycard, Asc
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein).

LRC15_MOUSE
NC score	0.054313 (rank : 67)	θ value	0.00102713 (rank : 32)
Query Neighborhood Hits	94	Target Neighborhood Hits	305	Shared Neighborhood Hits	31
SwissProt Accessions	Q80X72	Gene names	Lrrc15
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 15 precursor.

LRC18_HUMAN
NC score	0.053508 (rank : 68)	θ value	0.0961366 (rank : 38)
Query Neighborhood Hits	94	Target Neighborhood Hits	217	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N456, Q6UY02	Gene names	LRRC18
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 18.

PXDC2_HUMAN
NC score	0.050655 (rank : 69)	θ value	1.81305 (rank : 58)
Query Neighborhood Hits	94	Target Neighborhood Hits	29	Shared Neighborhood Hits	7
SwissProt Accessions	Q6UX71, Q96E59, Q96PD9, Q96SU9	Gene names	PLXDC2, TEM7R
Domain Architecture	No domain graphic available
Description	Plexin domain-containing protein 2 precursor (Tumor endothelial marker 7-related protein).

LRC47_MOUSE
NC score	0.048883 (rank : 70)	θ value	0.47712 (rank : 44)
Query Neighborhood Hits	94	Target Neighborhood Hits	299	Shared Neighborhood Hits	29
SwissProt Accessions	Q505F5, Q3U380, Q6ZPW2, Q9CUZ0	Gene names	Lrrc47, Kiaa1185
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 47.

TLR9_MOUSE
NC score	0.048076 (rank : 71)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	94	Target Neighborhood Hits	291	Shared Neighborhood Hits	31
SwissProt Accessions	Q9EQU3, Q99MF2, Q99MQ8	Gene names	Tlr9
Domain Architecture
Description	Toll-like receptor 9 precursor (CD289 antigen).

FLII_HUMAN
NC score	0.044680 (rank : 72)	θ value	0.365318 (rank : 42)
Query Neighborhood Hits	94	Target Neighborhood Hits	318	Shared Neighborhood Hits	31
SwissProt Accessions	Q13045	Gene names	FLII, FLIL
Domain Architecture
Description	Protein flightless-1 homolog.

LRC47_HUMAN
NC score	0.042451 (rank : 73)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	94	Target Neighborhood Hits	300	Shared Neighborhood Hits	29
SwissProt Accessions	Q8N1G4, Q9ULN5	Gene names	LRRC47, KIAA1185
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 47.

TLR8_MOUSE
NC score	0.042440 (rank : 74)	θ value	0.0252991 (rank : 35)
Query Neighborhood Hits	94	Target Neighborhood Hits	297	Shared Neighborhood Hits	27
SwissProt Accessions	P58682, Q91XI7	Gene names	Tlr8
Domain Architecture
Description	Toll-like receptor 8 precursor.

SHOC2_MOUSE
NC score	0.042249 (rank : 75)	θ value	1.38821 (rank : 56)
Query Neighborhood Hits	94	Target Neighborhood Hits	308	Shared Neighborhood Hits	28
SwissProt Accessions	O88520, Q3UJH6, Q8BVL0	Gene names	Shoc2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat protein SHOC-2 (Ras-binding protein Sur-8).

SHOC2_HUMAN
NC score	0.039313 (rank : 76)	θ value	1.38821 (rank : 55)
Query Neighborhood Hits	94	Target Neighborhood Hits	330	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UQ13, O76063	Gene names	SHOC2, KIAA0862
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat protein SHOC-2 (Ras-binding protein Sur-8).

LRRC7_MOUSE
NC score	0.037037 (rank : 77)	θ value	0.62314 (rank : 46)
Query Neighborhood Hits	94	Target Neighborhood Hits	416	Shared Neighborhood Hits	27
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRC7_HUMAN
NC score	0.035884 (rank : 78)	θ value	1.06291 (rank : 51)
Query Neighborhood Hits	94	Target Neighborhood Hits	423	Shared Neighborhood Hits	27
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

PHLPP_HUMAN
NC score	0.033687 (rank : 79)	θ value	0.279714 (rank : 41)
Query Neighborhood Hits	94	Target Neighborhood Hits	604	Shared Neighborhood Hits	27
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

GPV_MOUSE
NC score	0.033499 (rank : 80)	θ value	0.62314 (rank : 45)
Query Neighborhood Hits	94	Target Neighborhood Hits	293	Shared Neighborhood Hits	27
SwissProt Accessions	O08742	Gene names	Gp5
Domain Architecture	No domain graphic available
Description	Platelet glycoprotein V precursor (GPV) (CD42D antigen).

PHLPP_MOUSE
NC score	0.032640 (rank : 81)	θ value	0.62314 (rank : 48)
Query Neighborhood Hits	94	Target Neighborhood Hits	394	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

LRC8D_MOUSE
NC score	0.030361 (rank : 82)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	94	Target Neighborhood Hits	284	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BGR2, Q3UVA9, Q8CI13	Gene names	Lrrc8d, Lrrc5
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8D.

FBXL7_HUMAN
NC score	0.029083 (rank : 83)	θ value	0.163984 (rank : 40)
Query Neighborhood Hits	94	Target Neighborhood Hits	91	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UJT9, O94926	Gene names	FBXL7, FBL6, FBL7, KIAA0840
Domain Architecture
Description	F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7).

CPN2_HUMAN
NC score	0.027530 (rank : 84)	θ value	1.06291 (rank : 50)
Query Neighborhood Hits	94	Target Neighborhood Hits	279	Shared Neighborhood Hits	24
SwissProt Accessions	P22792, Q86SU4, Q8N5V4	Gene names	CPN2
Domain Architecture	No domain graphic available
Description	Carboxypeptidase N subunit 2 precursor (Carboxypeptidase N polypeptide 2) (Carboxypeptidase N 83 kDa chain) (Carboxypeptidase N regulatory subunit) (Carboxypeptidase N large subunit).

IF31_HUMAN
NC score	0.027001 (rank : 85)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	94	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	O75822, Q9BUD2, Q9H8Q2, Q9UI65	Gene names	EIF3S1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 1 (eIF-3 alpha) (eIF3 p35) (eIF3j).

SIX2_HUMAN
NC score	0.025566 (rank : 86)	θ value	2.36792 (rank : 62)
Query Neighborhood Hits	94	Target Neighborhood Hits	345	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NPC8, Q9BXH7	Gene names	SIX2
Domain Architecture
Description	Homeobox protein SIX2 (Sine oculis homeobox homolog 2).

SIX2_MOUSE
NC score	0.025200 (rank : 87)	θ value	2.36792 (rank : 63)
Query Neighborhood Hits	94	Target Neighborhood Hits	376	Shared Neighborhood Hits	8
SwissProt Accessions	Q62232, P70179	Gene names	Six2
Domain Architecture
Description	Homeobox protein SIX2 (Sine oculis homeobox homolog 2).

3BP1_MOUSE
NC score	0.024193 (rank : 88)	θ value	1.38821 (rank : 53)
Query Neighborhood Hits	94	Target Neighborhood Hits	238	Shared Neighborhood Hits	6
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

LRRN5_HUMAN
NC score	0.022922 (rank : 89)	θ value	0.62314 (rank : 47)
Query Neighborhood Hits	94	Target Neighborhood Hits	493	Shared Neighborhood Hits	25
SwissProt Accessions	O75325, Q5T0Y0, Q6UXM0, Q8N182	Gene names	LRRN5, GAC1, LRRN2
Domain Architecture
Description	Leucine-rich repeats neuronal protein 5 precursor (Glioma amplified on chromosome 1 protein).

CD180_MOUSE
NC score	0.021362 (rank : 90)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	94	Target Neighborhood Hits	283	Shared Neighborhood Hits	26
SwissProt Accessions	Q62192	Gene names	Cd180, Ly78, Rp105
Domain Architecture
Description	CD180 antigen precursor (Lymphocyte antigen 78) (Radioprotective 105 kDa protein).

SIX1_HUMAN
NC score	0.020012 (rank : 91)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	94	Target Neighborhood Hits	343	Shared Neighborhood Hits	8
SwissProt Accessions	Q15475, Q96H64	Gene names	SIX1
Domain Architecture
Description	Homeobox protein SIX1 (Sine oculis homeobox homolog 1).

SIX1_MOUSE
NC score	0.019999 (rank : 92)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	94	Target Neighborhood Hits	341	Shared Neighborhood Hits	8
SwissProt Accessions	Q62231, Q8CIL7	Gene names	Six1
Domain Architecture
Description	Homeobox protein SIX1 (Sine oculis homeobox homolog 1).

FLRT1_HUMAN
NC score	0.017403 (rank : 93)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	94	Target Neighborhood Hits	286	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NZU1	Gene names	FLRT1
Domain Architecture
Description	Leucine-rich repeat transmembrane protein FLRT1 precursor (Fibronectin-like domain-containing leucine-rich transmembrane protein 1).

NCOA2_HUMAN
NC score	0.016326 (rank : 94)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	94	Target Neighborhood Hits	281	Shared Neighborhood Hits	4
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

CPSM_MOUSE
NC score	0.012070 (rank : 95)	θ value	1.81305 (rank : 57)
Query Neighborhood Hits	94	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C196, Q6NX75	Gene names	Cps1
Domain Architecture	No domain graphic available
Description	Carbamoyl-phosphate synthase [ammonia], mitochondrial precursor (EC 6.3.4.16) (Carbamoyl-phosphate synthetase I) (CPSase I).

TRIM2_MOUSE
NC score	0.009384 (rank : 96)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	94	Target Neighborhood Hits	331	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRIM2_HUMAN
NC score	0.009349 (rank : 97)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	94	Target Neighborhood Hits	330	Shared Neighborhood Hits	7
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

OL498_MOUSE
NC score	0.008299 (rank : 98)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	94	Target Neighborhood Hits	642	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VEW2	Gene names	Olfr498, Mor204-36
Domain Architecture
Description	Olfactory receptor 498 (Olfactory receptor 204-36).

ABCF3_HUMAN
NC score	0.007458 (rank : 99)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	94	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NUQ8, Q86UA2, Q8NAN1, Q96GS8, Q9H7A8	Gene names	ABCF3
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 3.

ABCF3_MOUSE
NC score	0.007256 (rank : 100)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	94	Target Neighborhood Hits	126	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K268, Q9JL49	Gene names	Abcf3
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 3.

LSHR_MOUSE
NC score	0.006776 (rank : 101)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	94	Target Neighborhood Hits	686	Shared Neighborhood Hits	14
SwissProt Accessions	P30730	Gene names	Lhcgr, Lhr
Domain Architecture
Description	Lutropin-choriogonadotropic hormone receptor precursor (LH/CG-R) (LSH- R) (Luteinizing hormone receptor).

MX1_MOUSE
NC score	0.006456 (rank : 102)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	94	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	P09922	Gene names	Mx1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Influenza resistance protein).

OL494_MOUSE
NC score	0.006044 (rank : 103)	θ value	1.38821 (rank : 54)
Query Neighborhood Hits	94	Target Neighborhood Hits	689	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VG07	Gene names	Olfr494, Mor204-10
Domain Architecture
Description	Olfactory receptor 494 (Olfactory receptor 204-10).

OL497_MOUSE
NC score	0.004868 (rank : 104)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	94	Target Neighborhood Hits	687	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VG08	Gene names	Olfr497, Mor204-9
Domain Architecture
Description	Olfactory receptor 497 (Olfactory receptor 204-9).

RB6I2_HUMAN
NC score	0.004774 (rank : 105)	θ value	0.813845 (rank : 49)
Query Neighborhood Hits	94	Target Neighborhood Hits	1584	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

OL486_MOUSE
NC score	0.004766 (rank : 106)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	94	Target Neighborhood Hits	650	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VFD0	Gene names	Olfr486, Mor204-19
Domain Architecture
Description	Olfactory receptor 486 (Olfactory receptor 204-19).

OL495_MOUSE
NC score	0.004688 (rank : 107)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	94	Target Neighborhood Hits	666	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VF12	Gene names	Olfr495, Mor204-37
Domain Architecture
Description	Olfactory receptor 495 (Olfactory receptor 204-37).

OL507_MOUSE
NC score	0.004256 (rank : 108)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	94	Target Neighborhood Hits	635	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VG13	Gene names	Olfr507, Mor204-7
Domain Architecture
Description	Olfactory receptor 507 (Olfactory receptor 204-7).

OL510_MOUSE
NC score	0.004176 (rank : 109)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	94	Target Neighborhood Hits	681	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VEW6	Gene names	Olfr510, Mor204-34
Domain Architecture
Description	Olfactory receptor 510 (Olfactory receptor 204-34).

OL493_MOUSE
NC score	0.004120 (rank : 110)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	94	Target Neighborhood Hits	658	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VEW5	Gene names	Olfr493, Mor204-35
Domain Architecture
Description	Olfactory receptor 493 (Olfactory receptor 204-35).

EP15_MOUSE
NC score	0.003856 (rank : 111)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	94	Target Neighborhood Hits	820	Shared Neighborhood Hits	5
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

RB6I2_MOUSE
NC score	0.003738 (rank : 112)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	94	Target Neighborhood Hits	1433	Shared Neighborhood Hits	10
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

SPAG5_MOUSE
NC score	0.003563 (rank : 113)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	94	Target Neighborhood Hits	612	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

HDAC5_MOUSE
NC score	0.003210 (rank : 114)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	94	Target Neighborhood Hits	310	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2V6, Q9JL73	Gene names	Hdac5
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Histone deacetylase mHDA1).

OL490_MOUSE
NC score	0.002043 (rank : 115)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	94	Target Neighborhood Hits	691	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VFD2	Gene names	Olfr490, Mor204-17
Domain Architecture
Description	Olfactory receptor 490 (Olfactory receptor 204-17).

OL482_MOUSE
NC score	0.001713 (rank : 116)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	94	Target Neighborhood Hits	662	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VG03	Gene names	Olfr482, Mor204-14
Domain Architecture
Description	Olfactory receptor 482 (Olfactory receptor 204-14).

BAZ1A_HUMAN
NC score	0.001495 (rank : 117)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	94	Target Neighborhood Hits	693	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

PLK1_MOUSE
NC score	-0.001685 (rank : 118)	θ value	2.36792 (rank : 61)
Query Neighborhood Hits	94	Target Neighborhood Hits	849	Shared Neighborhood Hits	3
SwissProt Accessions	Q07832	Gene names	Plk1, Plk
Domain Architecture
Description	Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13).

PLK1_HUMAN
NC score	-0.001861 (rank : 119)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	94	Target Neighborhood Hits	849	Shared Neighborhood Hits	3
SwissProt Accessions	P53350, Q15153, Q99746	Gene names	PLK1, PLK
Domain Architecture
Description	Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13).