Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : CAR15_HUMAN

For an explanation of this page, click here

CAR15_HUMAN
SwissProt Accessions	Q9HC29, Q96RH5, Q96RH6, Q96RH8	Gene names	CARD15, IBD1, NOD2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2) (Inflammatory bowel disease protein 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CAR15_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	77	Target Neighborhood Hits	77	Shared Neighborhood Hits	77
SwissProt Accessions	Q9HC29, Q96RH5, Q96RH6, Q96RH8	Gene names	CARD15, IBD1, NOD2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2) (Inflammatory bowel disease protein 1).

CAR15_MOUSE
θ value	0 (rank : 2)	NC score	0.988470 (rank : 2)
Query Neighborhood Hits	77	Target Neighborhood Hits	93	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K3Z0	Gene names	Card15, Nod2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2).

CARD4_MOUSE
θ value	6.44497e-115 (rank : 3)	NC score	0.924702 (rank : 3)
Query Neighborhood Hits	77	Target Neighborhood Hits	85	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BHB0, Q8BUT6	Gene names	Card4
Domain Architecture
Description	Caspase recruitment domain-containing protein 4.

CARD4_HUMAN
θ value	2.37213e-109 (rank : 4)	NC score	0.914573 (rank : 4)
Query Neighborhood Hits	77	Target Neighborhood Hits	102	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y239, Q8IWF5	Gene names	CARD4, NOD1
Domain Architecture
Description	Caspase recruitment domain-containing protein 4 (Protein Nod1).

NAL12_HUMAN
θ value	1.52067e-31 (rank : 5)	NC score	0.757196 (rank : 5)
Query Neighborhood Hits	77	Target Neighborhood Hits	96	Shared Neighborhood Hits	46
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

CIAS1_MOUSE
θ value	7.06379e-29 (rank : 6)	NC score	0.740722 (rank : 7)
Query Neighborhood Hits	77	Target Neighborhood Hits	67	Shared Neighborhood Hits	41
SwissProt Accessions	Q8R4B8, Q6JEL0	Gene names	Cias1, Mmig1, Nalp3, Pypaf1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein homolog (PYRIN-containing APAF1-like protein 1) (Mast cell maturation-associated-inducible protein 1) (Cryopyrin).

CIAS1_HUMAN
θ value	1.92365e-26 (rank : 7)	NC score	0.743559 (rank : 6)
Query Neighborhood Hits	77	Target Neighborhood Hits	76	Shared Neighborhood Hits	39
SwissProt Accessions	Q96P20, O75434, Q59H68, Q5JQS8, Q5JQS9, Q6TG35, Q8TCW0, Q8TEU9, Q8WXH9	Gene names	CIAS1, NALP3, PYPAF1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein (Cryopyrin) (NACHT-, LRR- and PYD-containing protein 3) (PYRIN-containing APAF1-like protein 1) (Angiotensin/vasopressin receptor AII/AVP-like).

NAL14_HUMAN
θ value	1.24688e-25 (rank : 8)	NC score	0.732827 (rank : 9)
Query Neighborhood Hits	77	Target Neighborhood Hits	76	Shared Neighborhood Hits	39
SwissProt Accessions	Q86W24, Q7RTR6	Gene names	NALP14, NOD5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 14 (Nucleotide-binding oligomerization domain protein 5).

NALP4_HUMAN
θ value	2.87452e-22 (rank : 9)	NC score	0.732728 (rank : 10)
Query Neighborhood Hits	77	Target Neighborhood Hits	81	Shared Neighborhood Hits	44
SwissProt Accessions	Q96MN2, Q86W87, Q96AY6	Gene names	NALP4, PAN2, PYPAF4, RNH2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 4 (PYRIN-containing APAF1-like protein 4) (PAAD and NACHT-containing protein 2) (PYRIN and NACHT- containing protein 2) (Ribonuclease inhibitor 2).

C2TA_HUMAN
θ value	3.17815e-21 (rank : 10)	NC score	0.662299 (rank : 22)
Query Neighborhood Hits	77	Target Neighborhood Hits	190	Shared Neighborhood Hits	36
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

NALP2_HUMAN
θ value	5.42112e-21 (rank : 11)	NC score	0.733029 (rank : 8)
Query Neighborhood Hits	77	Target Neighborhood Hits	65	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NX02, Q53FL5, Q59G09, Q8IXT0, Q9BVN5, Q9H6G6, Q9HAV9, Q9NWK3	Gene names	NALP2, NBS1, PAN1, PYPAF2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 2 (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2) (Nucleotide-binding site protein 1).

NAL10_HUMAN
θ value	2.69047e-20 (rank : 12)	NC score	0.690103 (rank : 18)
Query Neighborhood Hits	77	Target Neighborhood Hits	55	Shared Neighborhood Hits	29
SwissProt Accessions	Q86W26, Q6JGT0	Gene names	NALP10, NOD8, PYNOD
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10 (Nucleotide-binding oligomerization domain protein 8).

NALP1_HUMAN
θ value	7.82807e-20 (rank : 13)	NC score	0.696370 (rank : 16)
Query Neighborhood Hits	77	Target Neighborhood Hits	138	Shared Neighborhood Hits	41
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

NALP6_MOUSE
θ value	2.13179e-17 (rank : 14)	NC score	0.698672 (rank : 15)
Query Neighborhood Hits	77	Target Neighborhood Hits	55	Shared Neighborhood Hits	35
SwissProt Accessions	Q91WS2, Q8K0L4	Gene names	Nalp6, Pypaf5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5-like).

C2TA_MOUSE
θ value	1.058e-16 (rank : 15)	NC score	0.689298 (rank : 19)
Query Neighborhood Hits	77	Target Neighborhood Hits	131	Shared Neighborhood Hits	49
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).

NALP6_HUMAN
θ value	1.058e-16 (rank : 16)	NC score	0.692781 (rank : 17)
Query Neighborhood Hits	77	Target Neighborhood Hits	52	Shared Neighborhood Hits	33
SwissProt Accessions	P59044	Gene names	NALP6, PYPAF5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5).

NALP5_HUMAN
θ value	1.38178e-16 (rank : 17)	NC score	0.699622 (rank : 14)
Query Neighborhood Hits	77	Target Neighborhood Hits	88	Shared Neighborhood Hits	40
SwissProt Accessions	P59047, Q86W29	Gene names	NALP5, MATER
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Mater protein homolog).

NAL13_HUMAN
θ value	5.8054e-15 (rank : 18)	NC score	0.719479 (rank : 12)
Query Neighborhood Hits	77	Target Neighborhood Hits	93	Shared Neighborhood Hits	41
SwissProt Accessions	Q86W25, Q7RTR5	Gene names	NALP13, NOD14
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 13 (Nucleotide-binding oligomerization domain protein 14).

RINI_HUMAN
θ value	5.8054e-15 (rank : 19)	NC score	0.701214 (rank : 13)
Query Neighborhood Hits	77	Target Neighborhood Hits	78	Shared Neighborhood Hits	43
SwissProt Accessions	P13489	Gene names	RNH1, PRI, RNH
Domain Architecture
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1) (RAI) (Placental ribonuclease inhibitor) (RNase inhibitor) (RI).

NALP7_HUMAN
θ value	1.68911e-14 (rank : 20)	NC score	0.720065 (rank : 11)
Query Neighborhood Hits	77	Target Neighborhood Hits	65	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WX94, Q7RTR1	Gene names	NALP7, NOD12, PYPAF3
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 7 (PYRIN-containing APAF1-like protein 3).

LRC45_HUMAN
θ value	2.20605e-14 (rank : 21)	NC score	0.237036 (rank : 39)
Query Neighborhood Hits	77	Target Neighborhood Hits	933	Shared Neighborhood Hits	36
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

RINI_MOUSE
θ value	1.09485e-13 (rank : 22)	NC score	0.689089 (rank : 20)
Query Neighborhood Hits	77	Target Neighborhood Hits	87	Shared Neighborhood Hits	40
SwissProt Accessions	Q91VI7, Q924P4	Gene names	Rnh1, Rnh
Domain Architecture	No domain graphic available
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1).

LRC34_HUMAN
θ value	1.58096e-12 (rank : 23)	NC score	0.638791 (rank : 25)
Query Neighborhood Hits	77	Target Neighborhood Hits	67	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IZ02	Gene names	LRRC34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

LRC45_MOUSE
θ value	2.69671e-12 (rank : 24)	NC score	0.242088 (rank : 38)
Query Neighborhood Hits	77	Target Neighborhood Hits	959	Shared Neighborhood Hits	40
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

NAL11_HUMAN
θ value	2.28291e-11 (rank : 25)	NC score	0.659765 (rank : 23)
Query Neighborhood Hits	77	Target Neighborhood Hits	66	Shared Neighborhood Hits	37
SwissProt Accessions	P59045, Q53ZZ0, Q8NBF5	Gene names	NALP11, NOD17, PYPAF6
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 11 (PYRIN-containing APAF1-like protein 6) (Nucleotide-binding oligomerization domain protein 17).

NALP5_MOUSE
θ value	2.98157e-11 (rank : 26)	NC score	0.655849 (rank : 24)
Query Neighborhood Hits	77	Target Neighborhood Hits	560	Shared Neighborhood Hits	40
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

NAL10_MOUSE
θ value	5.08577e-11 (rank : 27)	NC score	0.675397 (rank : 21)
Query Neighborhood Hits	77	Target Neighborhood Hits	46	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CCN1	Gene names	Nalp10, Pynod
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10.

LRC34_MOUSE
θ value	2.36244e-08 (rank : 28)	NC score	0.596688 (rank : 26)
Query Neighborhood Hits	77	Target Neighborhood Hits	58	Shared Neighborhood Hits	36
SwissProt Accessions	Q9DAM1	Gene names	Lrrc34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

RGP1_HUMAN
θ value	2.61198e-07 (rank : 29)	NC score	0.428046 (rank : 29)
Query Neighborhood Hits	77	Target Neighborhood Hits	124	Shared Neighborhood Hits	26
SwissProt Accessions	P46060	Gene names	RANGAP1
Domain Architecture
Description	Ran GTPase-activating protein 1.

TMOD1_HUMAN
θ value	3.77169e-06 (rank : 30)	NC score	0.233639 (rank : 41)
Query Neighborhood Hits	77	Target Neighborhood Hits	32	Shared Neighborhood Hits	20
SwissProt Accessions	P28289, Q9BUF1	Gene names	TMOD1, TMOD
Domain Architecture
Description	Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod).

TMOD1_MOUSE
θ value	4.92598e-06 (rank : 31)	NC score	0.234633 (rank : 40)
Query Neighborhood Hits	77	Target Neighborhood Hits	28	Shared Neighborhood Hits	19
SwissProt Accessions	P49813, Q9ERR9	Gene names	Tmod1, Tmod
Domain Architecture
Description	Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod).

BIR1F_MOUSE
θ value	6.43352e-06 (rank : 32)	NC score	0.258514 (rank : 33)
Query Neighborhood Hits	77	Target Neighborhood Hits	88	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JIB6, O09121, O09122, P81704	Gene names	Birc1f, Naip-rs4, Naip6
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).

RGP1_MOUSE
θ value	6.43352e-06 (rank : 33)	NC score	0.396021 (rank : 30)
Query Neighborhood Hits	77	Target Neighborhood Hits	105	Shared Neighborhood Hits	26
SwissProt Accessions	P46061, Q60801	Gene names	Rangap1, Fug1
Domain Architecture
Description	Ran GTPase-activating protein 1.

BIR1B_MOUSE
θ value	8.40245e-06 (rank : 34)	NC score	0.255486 (rank : 34)
Query Neighborhood Hits	77	Target Neighborhood Hits	93	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QUK4, O09124, Q9R030	Gene names	Birc1b, Naip-rs6, Naip2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2).

BIR1G_MOUSE
θ value	3.19293e-05 (rank : 35)	NC score	0.252205 (rank : 36)
Query Neighborhood Hits	77	Target Neighborhood Hits	92	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JIB3	Gene names	Birc1g, Naip7
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).

CAR12_HUMAN
θ value	4.1701e-05 (rank : 36)	NC score	0.386019 (rank : 31)
Query Neighborhood Hits	77	Target Neighborhood Hits	132	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NPP4, Q96J81, Q96J82, Q96J83	Gene names	CARD12, CLAN, CLAN1
Domain Architecture
Description	Caspase recruitment domain-containing protein 12 (Ice protease- activating factor) (Ipaf) (CARD, LRR, and NACHT-containing protein) (Clan protein).

BIR1E_MOUSE
θ value	7.1131e-05 (rank : 37)	NC score	0.251053 (rank : 37)
Query Neighborhood Hits	77	Target Neighborhood Hits	93	Shared Neighborhood Hits	30
SwissProt Accessions	Q9R016, O09121, O09122, P81703, Q9R029	Gene names	Birc1e, Naip-rs3, Naip5
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).

BIR1A_MOUSE
θ value	0.000602161 (rank : 38)	NC score	0.255118 (rank : 35)
Query Neighborhood Hits	77	Target Neighborhood Hits	94	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QWK5, Q9JIB5, Q9R017	Gene names	Birc1a, Naip, Naip1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1).

BIRC1_HUMAN
θ value	0.00134147 (rank : 39)	NC score	0.269204 (rank : 32)
Query Neighborhood Hits	77	Target Neighborhood Hits	61	Shared Neighborhood Hits	30
SwissProt Accessions	Q13075, O75857, Q13730, Q99796	Gene names	BIRC1, NAIP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein).

TMOD4_MOUSE
θ value	0.00228821 (rank : 40)	NC score	0.215985 (rank : 45)
Query Neighborhood Hits	77	Target Neighborhood Hits	36	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JLH8	Gene names	Tmod4
Domain Architecture
Description	Tropomodulin-4 (Skeletal muscle tropomodulin) (Sk-Tmod).

TMOD2_HUMAN
θ value	0.00298849 (rank : 41)	NC score	0.231046 (rank : 42)
Query Neighborhood Hits	77	Target Neighborhood Hits	29	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZR1	Gene names	TMOD2, NTMOD
Domain Architecture
Description	Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod).

TMOD4_HUMAN
θ value	0.00298849 (rank : 42)	NC score	0.218528 (rank : 43)
Query Neighborhood Hits	77	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZQ9, Q8WVL3, Q9UKH2	Gene names	TMOD4
Domain Architecture
Description	Tropomodulin-4 (Skeletal muscle tropomodulin) (Sk-Tmod).

LRC31_HUMAN
θ value	0.00665767 (rank : 43)	NC score	0.441380 (rank : 28)
Query Neighborhood Hits	77	Target Neighborhood Hits	139	Shared Neighborhood Hits	42
SwissProt Accessions	Q6UY01, Q8N848, Q9H5N5	Gene names	LRRC31
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 31.

TMOD3_HUMAN
θ value	0.0148317 (rank : 44)	NC score	0.214543 (rank : 46)
Query Neighborhood Hits	77	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NYL9, Q9NT43, Q9NZR0	Gene names	TMOD3
Domain Architecture
Description	Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod).

TMOD3_MOUSE
θ value	0.0330416 (rank : 45)	NC score	0.217555 (rank : 44)
Query Neighborhood Hits	77	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JHJ0, Q3TIT1	Gene names	Tmod3
Domain Architecture
Description	Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod).

LRC57_HUMAN
θ value	0.0431538 (rank : 46)	NC score	0.060143 (rank : 65)
Query Neighborhood Hits	77	Target Neighborhood Hits	271	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N9N7, Q7Z2Z6, Q8N1T6	Gene names	LRRC57
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 57.

LAP4_MOUSE
θ value	0.0736092 (rank : 47)	NC score	0.030582 (rank : 74)
Query Neighborhood Hits	77	Target Neighborhood Hits	590	Shared Neighborhood Hits	20
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

LRC57_MOUSE
θ value	0.0961366 (rank : 48)	NC score	0.055231 (rank : 70)
Query Neighborhood Hits	77	Target Neighborhood Hits	267	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D1G5, Q9DC95	Gene names	Lrrc57
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 57.

LMD1_HUMAN
θ value	0.125558 (rank : 49)	NC score	0.208763 (rank : 47)
Query Neighborhood Hits	77	Target Neighborhood Hits	169	Shared Neighborhood Hits	17
SwissProt Accessions	P29536	Gene names	LMOD1
Domain Architecture
Description	Leiomodin-1 (Leiomodin, muscle form) (64 kDa autoantigen D1) (64 kDa autoantigen 1D) (64 kDa autoantigen 1D3) (Thyroid-associated ophthalmopathy autoantigen) (Smooth muscle leiomodin) (SM-Lmod).

LRC47_HUMAN
θ value	0.21417 (rank : 50)	NC score	0.048748 (rank : 73)
Query Neighborhood Hits	77	Target Neighborhood Hits	300	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N1G4, Q9ULN5	Gene names	LRRC47, KIAA1185
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 47.

LRC47_MOUSE
θ value	0.47712 (rank : 51)	NC score	0.054893 (rank : 71)
Query Neighborhood Hits	77	Target Neighborhood Hits	299	Shared Neighborhood Hits	23
SwissProt Accessions	Q505F5, Q3U380, Q6ZPW2, Q9CUZ0	Gene names	Lrrc47, Kiaa1185
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 47.

LRIG3_HUMAN
θ value	0.47712 (rank : 52)	NC score	0.014590 (rank : 86)
Query Neighborhood Hits	77	Target Neighborhood Hits	601	Shared Neighborhood Hits	17
SwissProt Accessions	Q6UXM1, Q6UXL7, Q8NC72	Gene names	LRIG3, LIG3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor (LIG-3).

NOL3_HUMAN
θ value	0.62314 (rank : 53)	NC score	0.119969 (rank : 51)
Query Neighborhood Hits	77	Target Neighborhood Hits	49	Shared Neighborhood Hits	7
SwissProt Accessions	O60936, O60937	Gene names	NOL3, ARC, NOP
Domain Architecture
Description	Nucleolar protein 3 (Apoptosis repressor with CARD) (Muscle-enriched cytoplasmic protein) (Myp) (Nucleolar protein of 30 kDa) (Nop30).

RAVR1_HUMAN
θ value	0.62314 (rank : 54)	NC score	0.022380 (rank : 80)
Query Neighborhood Hits	77	Target Neighborhood Hits	159	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IY67, Q8IY60, Q8TF24	Gene names	RAVER1, KIAA1978
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 1 (Protein raver-1).

PGS2_MOUSE
θ value	0.813845 (rank : 55)	NC score	0.024468 (rank : 78)
Query Neighborhood Hits	77	Target Neighborhood Hits	285	Shared Neighborhood Hits	18
SwissProt Accessions	P28654	Gene names	Dcn
Domain Architecture
Description	Decorin precursor (Bone proteoglycan II) (PG-S2) (PG40).

CARD6_HUMAN
θ value	1.06291 (rank : 56)	NC score	0.055612 (rank : 68)
Query Neighborhood Hits	77	Target Neighborhood Hits	145	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BX69	Gene names	CARD6
Domain Architecture
Description	Caspase recruitment domain-containing protein 6.

LRC8A_HUMAN
θ value	1.06291 (rank : 57)	NC score	0.028542 (rank : 75)
Query Neighborhood Hits	77	Target Neighborhood Hits	274	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IWT6, Q6UXM2, Q8NCI0, Q9P2B1	Gene names	LRRC8A, KIAA1437, LRRC8
Domain Architecture
Description	Leucine-rich repeat-containing protein 8A.

NOL3_MOUSE
θ value	1.06291 (rank : 58)	NC score	0.105941 (rank : 52)
Query Neighborhood Hits	77	Target Neighborhood Hits	97	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D1X0	Gene names	Nol3
Domain Architecture
Description	Nucleolar protein 3.

BIRC2_MOUSE
θ value	1.38821 (rank : 59)	NC score	0.086336 (rank : 53)
Query Neighborhood Hits	77	Target Neighborhood Hits	137	Shared Neighborhood Hits	15
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

CF154_HUMAN
θ value	1.38821 (rank : 60)	NC score	0.454918 (rank : 27)
Query Neighborhood Hits	77	Target Neighborhood Hits	36	Shared Neighborhood Hits	30
SwissProt Accessions	Q5JTD7	Gene names	C6orf154
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf154.

LRC8A_MOUSE
θ value	1.38821 (rank : 61)	NC score	0.027867 (rank : 76)
Query Neighborhood Hits	77	Target Neighborhood Hits	274	Shared Neighborhood Hits	21
SwissProt Accessions	Q80WG5	Gene names	Lrrc8a, Lrrc8
Domain Architecture
Description	Leucine-rich repeat-containing protein 8A.

DIRA3_HUMAN
θ value	1.81305 (rank : 62)	NC score	0.014334 (rank : 87)
Query Neighborhood Hits	77	Target Neighborhood Hits	241	Shared Neighborhood Hits	9
SwissProt Accessions	O95661	Gene names	DIRAS3, ARHI, NOEY2, RHOI
Domain Architecture
Description	GTP-binding protein Di-Ras3 (Distinct subgroup of the Ras family member 3) (Rho-related GTP-binding protein RhoI).

LRFN4_HUMAN
θ value	1.81305 (rank : 63)	NC score	0.018991 (rank : 82)
Query Neighborhood Hits	77	Target Neighborhood Hits	462	Shared Neighborhood Hits	17
SwissProt Accessions	Q6PJG9, Q9BWJ0	Gene names	LRFN4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

LRFN4_MOUSE
θ value	1.81305 (rank : 64)	NC score	0.014629 (rank : 85)
Query Neighborhood Hits	77	Target Neighborhood Hits	442	Shared Neighborhood Hits	15
SwissProt Accessions	Q80XU8, Q3TQG8, Q8K3C4	Gene names	Lrfn4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

LRIG2_MOUSE
θ value	3.0926 (rank : 65)	NC score	0.014301 (rank : 88)
Query Neighborhood Hits	77	Target Neighborhood Hits	586	Shared Neighborhood Hits	18
SwissProt Accessions	Q52KR2, Q69ZY8	Gene names	Lrig2, Kiaa0806
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor.

RAVR1_MOUSE
θ value	3.0926 (rank : 66)	NC score	0.017907 (rank : 84)
Query Neighborhood Hits	77	Target Neighborhood Hits	179	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CW46, Q5DTT6, Q811K0, Q8C3Z1, Q8CA14	Gene names	Raver1, Kiaa1978
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 1 (Protein raver-1).

CASP1_HUMAN
θ value	5.27518 (rank : 67)	NC score	0.021673 (rank : 81)
Query Neighborhood Hits	77	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	P29466, Q9UCN3	Gene names	CASP1, IL1BC, IL1BCE
Domain Architecture
Description	Caspase-1 precursor (EC 3.4.22.36) (CASP-1) (Interleukin-1 beta convertase) (IL-1BC) (IL-1 beta-converting enzyme) (ICE) (Interleukin- 1 beta-converting enzyme) (p45) [Contains: Caspase-1 p20 subunit; Caspase-1 p10 subunit].

CASP1_MOUSE
θ value	5.27518 (rank : 68)	NC score	0.027474 (rank : 77)
Query Neighborhood Hits	77	Target Neighborhood Hits	38	Shared Neighborhood Hits	10
SwissProt Accessions	P29452	Gene names	Casp1, Il1bc
Domain Architecture
Description	Caspase-1 precursor (EC 3.4.22.36) (CASP-1) (Interleukin-1 beta convertase) (IL-1BC) (IL-1 beta-converting enzyme) (ICE) (Interleukin- 1 beta-converting enzyme) (p45) [Contains: Caspase-1 p20 subunit; Caspase-1 p10 subunit].

LRSM1_HUMAN
θ value	5.27518 (rank : 69)	NC score	0.018563 (rank : 83)
Query Neighborhood Hits	77	Target Neighborhood Hits	1078	Shared Neighborhood Hits	17
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

P3H2_HUMAN
θ value	5.27518 (rank : 70)	NC score	0.010516 (rank : 89)
Query Neighborhood Hits	77	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IVL5, Q9NVI2	Gene names	LEPREL1, MLAT4, P3H2
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 2 precursor (EC 1.14.11.7) (Leprecan-like protein 1) (Myxoid liposarcoma-associated protein 4).

RHOD_HUMAN
θ value	5.27518 (rank : 71)	NC score	0.001485 (rank : 91)
Query Neighborhood Hits	77	Target Neighborhood Hits	262	Shared Neighborhood Hits	4
SwissProt Accessions	O00212	Gene names	RHOD, ARHD
Domain Architecture
Description	Rho-related GTP-binding protein RhoD precursor (Rho-related protein HP1) (RhoHP1).

LLR1_HUMAN
θ value	6.88961 (rank : 72)	NC score	0.023221 (rank : 79)
Query Neighborhood Hits	77	Target Neighborhood Hits	225	Shared Neighborhood Hits	15
SwissProt Accessions	Q96L50, Q86SZ1, Q8N6H9	Gene names	PPIL5, LRR1
Domain Architecture
Description	Peptidylprolyl isomerase-like 5 (LRR-repeat protein 1) (LRR-1) (4-1BB- mediated signaling molecule) (4-1BBlrr).

LRC41_HUMAN
θ value	6.88961 (rank : 73)	NC score	0.064375 (rank : 61)
Query Neighborhood Hits	77	Target Neighborhood Hits	51	Shared Neighborhood Hits	17
SwissProt Accessions	Q15345, Q71RA8, Q9BSM0	Gene names	LRRC41, MUF1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 41 (Protein Muf1).

RAB26_MOUSE
θ value	6.88961 (rank : 74)	NC score	0.000242 (rank : 92)
Query Neighborhood Hits	77	Target Neighborhood Hits	287	Shared Neighborhood Hits	4
SwissProt Accessions	Q504M8	Gene names	Rab26
Domain Architecture	No domain graphic available
Description	Ras-related protein Rab-26.

ICBR_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.055235 (rank : 69)
Query Neighborhood Hits	77	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	P57730	Gene names	ICEBERG
Domain Architecture
Description	Caspase-1 inhibitor Iceberg.

LRC41_MOUSE
θ value	8.99809 (rank : 76)	NC score	0.063149 (rank : 62)
Query Neighborhood Hits	77	Target Neighborhood Hits	37	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K1C9, Q91VX4	Gene names	Lrrc41, Muf1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 41 (Protein Muf1).

OSBL3_MOUSE
θ value	8.99809 (rank : 77)	NC score	0.003687 (rank : 90)
Query Neighborhood Hits	77	Target Neighborhood Hits	86	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

ASC_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.139611 (rank : 50)
Query Neighborhood Hits	77	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ULZ3, Q96D12, Q9BSZ5, Q9HBD0, Q9NXJ8	Gene names	PYCARD, ASC, CARD5, TMS1
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (hASC) (PYD and CARD domain-containing protein) (Target of methylation-induced silencing 1) (Caspase recruitment domain-containing protein 5).

ASC_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.162638 (rank : 49)
Query Neighborhood Hits	77	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	Q9EPB4, Q9D2W9	Gene names	Pycard, Asc
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein).

BIRC2_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.079426 (rank : 56)
Query Neighborhood Hits	77	Target Neighborhood Hits	142	Shared Neighborhood Hits	14
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

BIRC3_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.066281 (rank : 58)
Query Neighborhood Hits	77	Target Neighborhood Hits	133	Shared Neighborhood Hits	12
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

BIRC3_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.064627 (rank : 60)
Query Neighborhood Hits	77	Target Neighborhood Hits	113	Shared Neighborhood Hits	9
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

BIRC4_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.065525 (rank : 59)
Query Neighborhood Hits	77	Target Neighborhood Hits	89	Shared Neighborhood Hits	8
SwissProt Accessions	P98170, Q9NQ14	Gene names	BIRC4, API3, IAP3, XIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP).

BIRC4_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.066682 (rank : 57)
Query Neighborhood Hits	77	Target Neighborhood Hits	89	Shared Neighborhood Hits	8
SwissProt Accessions	Q60989, O08865	Gene names	Birc4, Aipa, Api3, Miha, Xiap
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3).

BIRC5_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.060788 (rank : 64)
Query Neighborhood Hits	77	Target Neighborhood Hits	20	Shared Neighborhood Hits	7
SwissProt Accessions	O15392, Q2I3N8, Q4VGX0, Q53F61, Q5MGC6, Q6FHL2, Q75SP2, Q9P2W8	Gene names	BIRC5, API4, IAP4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4).

BIRC5_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.059878 (rank : 66)
Query Neighborhood Hits	77	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	O70201, Q923F7, Q9WU53, Q9WU54	Gene names	Birc5, Api4, Iap4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4) (TIAP).

BIRC7_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.059061 (rank : 67)
Query Neighborhood Hits	77	Target Neighborhood Hits	185	Shared Neighborhood Hits	8
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

BIRC8_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.053829 (rank : 72)
Query Neighborhood Hits	77	Target Neighborhood Hits	121	Shared Neighborhood Hits	8
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

CARD8_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.083740 (rank : 55)
Query Neighborhood Hits	77	Target Neighborhood Hits	22	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y2G2, Q6PGP8, Q96P82	Gene names	CARD8, KIAA0955, NDPP1
Domain Architecture
Description	Caspase recruitment domain-containing protein 8 (Apoptotic protein NDPP1) (DACAR) (CARD-inhibitor of NF-kappa-B-activating ligand) (CARDINAL) (Tumor-up-regulated CARD-containing antagonist of CASP9) (TUCAN).

LRC14_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.062976 (rank : 63)
Query Neighborhood Hits	77	Target Neighborhood Hits	57	Shared Neighborhood Hits	17
SwissProt Accessions	Q15048	Gene names	LRRC14, KIAA0014
Domain Architecture
Description	Leucine-rich repeat-containing protein 14.

MEFV_MOUSE
θ value	θ > 10 (rank : 91)	NC score	0.084297 (rank : 54)
Query Neighborhood Hits	77	Target Neighborhood Hits	236	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

TMOD2_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.206441 (rank : 48)
Query Neighborhood Hits	77	Target Neighborhood Hits	41	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JKK7, Q9JLH9	Gene names	Tmod2
Domain Architecture
Description	Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod).

Hits sorted by NC score

CAR15_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	77	Target Neighborhood Hits	77	Shared Neighborhood Hits	77
SwissProt Accessions	Q9HC29, Q96RH5, Q96RH6, Q96RH8	Gene names	CARD15, IBD1, NOD2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2) (Inflammatory bowel disease protein 1).

CAR15_MOUSE
NC score	0.988470 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	77	Target Neighborhood Hits	93	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K3Z0	Gene names	Card15, Nod2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2).

CARD4_MOUSE
NC score	0.924702 (rank : 3)	θ value	6.44497e-115 (rank : 3)
Query Neighborhood Hits	77	Target Neighborhood Hits	85	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BHB0, Q8BUT6	Gene names	Card4
Domain Architecture
Description	Caspase recruitment domain-containing protein 4.

CARD4_HUMAN
NC score	0.914573 (rank : 4)	θ value	2.37213e-109 (rank : 4)
Query Neighborhood Hits	77	Target Neighborhood Hits	102	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y239, Q8IWF5	Gene names	CARD4, NOD1
Domain Architecture
Description	Caspase recruitment domain-containing protein 4 (Protein Nod1).

NAL12_HUMAN
NC score	0.757196 (rank : 5)	θ value	1.52067e-31 (rank : 5)
Query Neighborhood Hits	77	Target Neighborhood Hits	96	Shared Neighborhood Hits	46
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

CIAS1_HUMAN
NC score	0.743559 (rank : 6)	θ value	1.92365e-26 (rank : 7)
Query Neighborhood Hits	77	Target Neighborhood Hits	76	Shared Neighborhood Hits	39
SwissProt Accessions	Q96P20, O75434, Q59H68, Q5JQS8, Q5JQS9, Q6TG35, Q8TCW0, Q8TEU9, Q8WXH9	Gene names	CIAS1, NALP3, PYPAF1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein (Cryopyrin) (NACHT-, LRR- and PYD-containing protein 3) (PYRIN-containing APAF1-like protein 1) (Angiotensin/vasopressin receptor AII/AVP-like).

CIAS1_MOUSE
NC score	0.740722 (rank : 7)	θ value	7.06379e-29 (rank : 6)
Query Neighborhood Hits	77	Target Neighborhood Hits	67	Shared Neighborhood Hits	41
SwissProt Accessions	Q8R4B8, Q6JEL0	Gene names	Cias1, Mmig1, Nalp3, Pypaf1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein homolog (PYRIN-containing APAF1-like protein 1) (Mast cell maturation-associated-inducible protein 1) (Cryopyrin).

NALP2_HUMAN
NC score	0.733029 (rank : 8)	θ value	5.42112e-21 (rank : 11)
Query Neighborhood Hits	77	Target Neighborhood Hits	65	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NX02, Q53FL5, Q59G09, Q8IXT0, Q9BVN5, Q9H6G6, Q9HAV9, Q9NWK3	Gene names	NALP2, NBS1, PAN1, PYPAF2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 2 (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2) (Nucleotide-binding site protein 1).

NAL14_HUMAN
NC score	0.732827 (rank : 9)	θ value	1.24688e-25 (rank : 8)
Query Neighborhood Hits	77	Target Neighborhood Hits	76	Shared Neighborhood Hits	39
SwissProt Accessions	Q86W24, Q7RTR6	Gene names	NALP14, NOD5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 14 (Nucleotide-binding oligomerization domain protein 5).

NALP4_HUMAN
NC score	0.732728 (rank : 10)	θ value	2.87452e-22 (rank : 9)
Query Neighborhood Hits	77	Target Neighborhood Hits	81	Shared Neighborhood Hits	44
SwissProt Accessions	Q96MN2, Q86W87, Q96AY6	Gene names	NALP4, PAN2, PYPAF4, RNH2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 4 (PYRIN-containing APAF1-like protein 4) (PAAD and NACHT-containing protein 2) (PYRIN and NACHT- containing protein 2) (Ribonuclease inhibitor 2).

NALP7_HUMAN
NC score	0.720065 (rank : 11)	θ value	1.68911e-14 (rank : 20)
Query Neighborhood Hits	77	Target Neighborhood Hits	65	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WX94, Q7RTR1	Gene names	NALP7, NOD12, PYPAF3
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 7 (PYRIN-containing APAF1-like protein 3).

NAL13_HUMAN
NC score	0.719479 (rank : 12)	θ value	5.8054e-15 (rank : 18)
Query Neighborhood Hits	77	Target Neighborhood Hits	93	Shared Neighborhood Hits	41
SwissProt Accessions	Q86W25, Q7RTR5	Gene names	NALP13, NOD14
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 13 (Nucleotide-binding oligomerization domain protein 14).

RINI_HUMAN
NC score	0.701214 (rank : 13)	θ value	5.8054e-15 (rank : 19)
Query Neighborhood Hits	77	Target Neighborhood Hits	78	Shared Neighborhood Hits	43
SwissProt Accessions	P13489	Gene names	RNH1, PRI, RNH
Domain Architecture
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1) (RAI) (Placental ribonuclease inhibitor) (RNase inhibitor) (RI).

NALP5_HUMAN
NC score	0.699622 (rank : 14)	θ value	1.38178e-16 (rank : 17)
Query Neighborhood Hits	77	Target Neighborhood Hits	88	Shared Neighborhood Hits	40
SwissProt Accessions	P59047, Q86W29	Gene names	NALP5, MATER
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Mater protein homolog).

NALP6_MOUSE
NC score	0.698672 (rank : 15)	θ value	2.13179e-17 (rank : 14)
Query Neighborhood Hits	77	Target Neighborhood Hits	55	Shared Neighborhood Hits	35
SwissProt Accessions	Q91WS2, Q8K0L4	Gene names	Nalp6, Pypaf5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5-like).

NALP1_HUMAN
NC score	0.696370 (rank : 16)	θ value	7.82807e-20 (rank : 13)
Query Neighborhood Hits	77	Target Neighborhood Hits	138	Shared Neighborhood Hits	41
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

NALP6_HUMAN
NC score	0.692781 (rank : 17)	θ value	1.058e-16 (rank : 16)
Query Neighborhood Hits	77	Target Neighborhood Hits	52	Shared Neighborhood Hits	33
SwissProt Accessions	P59044	Gene names	NALP6, PYPAF5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5).

NAL10_HUMAN
NC score	0.690103 (rank : 18)	θ value	2.69047e-20 (rank : 12)
Query Neighborhood Hits	77	Target Neighborhood Hits	55	Shared Neighborhood Hits	29
SwissProt Accessions	Q86W26, Q6JGT0	Gene names	NALP10, NOD8, PYNOD
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10 (Nucleotide-binding oligomerization domain protein 8).

C2TA_MOUSE
NC score	0.689298 (rank : 19)	θ value	1.058e-16 (rank : 15)
Query Neighborhood Hits	77	Target Neighborhood Hits	131	Shared Neighborhood Hits	49
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).

RINI_MOUSE
NC score	0.689089 (rank : 20)	θ value	1.09485e-13 (rank : 22)
Query Neighborhood Hits	77	Target Neighborhood Hits	87	Shared Neighborhood Hits	40
SwissProt Accessions	Q91VI7, Q924P4	Gene names	Rnh1, Rnh
Domain Architecture	No domain graphic available
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1).

NAL10_MOUSE
NC score	0.675397 (rank : 21)	θ value	5.08577e-11 (rank : 27)
Query Neighborhood Hits	77	Target Neighborhood Hits	46	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CCN1	Gene names	Nalp10, Pynod
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10.

C2TA_HUMAN
NC score	0.662299 (rank : 22)	θ value	3.17815e-21 (rank : 10)
Query Neighborhood Hits	77	Target Neighborhood Hits	190	Shared Neighborhood Hits	36
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

NAL11_HUMAN
NC score	0.659765 (rank : 23)	θ value	2.28291e-11 (rank : 25)
Query Neighborhood Hits	77	Target Neighborhood Hits	66	Shared Neighborhood Hits	37
SwissProt Accessions	P59045, Q53ZZ0, Q8NBF5	Gene names	NALP11, NOD17, PYPAF6
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 11 (PYRIN-containing APAF1-like protein 6) (Nucleotide-binding oligomerization domain protein 17).

NALP5_MOUSE
NC score	0.655849 (rank : 24)	θ value	2.98157e-11 (rank : 26)
Query Neighborhood Hits	77	Target Neighborhood Hits	560	Shared Neighborhood Hits	40
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

LRC34_HUMAN
NC score	0.638791 (rank : 25)	θ value	1.58096e-12 (rank : 23)
Query Neighborhood Hits	77	Target Neighborhood Hits	67	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IZ02	Gene names	LRRC34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

LRC34_MOUSE
NC score	0.596688 (rank : 26)	θ value	2.36244e-08 (rank : 28)
Query Neighborhood Hits	77	Target Neighborhood Hits	58	Shared Neighborhood Hits	36
SwissProt Accessions	Q9DAM1	Gene names	Lrrc34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

CF154_HUMAN
NC score	0.454918 (rank : 27)	θ value	1.38821 (rank : 60)
Query Neighborhood Hits	77	Target Neighborhood Hits	36	Shared Neighborhood Hits	30
SwissProt Accessions	Q5JTD7	Gene names	C6orf154
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf154.

LRC31_HUMAN
NC score	0.441380 (rank : 28)	θ value	0.00665767 (rank : 43)
Query Neighborhood Hits	77	Target Neighborhood Hits	139	Shared Neighborhood Hits	42
SwissProt Accessions	Q6UY01, Q8N848, Q9H5N5	Gene names	LRRC31
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 31.

RGP1_HUMAN
NC score	0.428046 (rank : 29)	θ value	2.61198e-07 (rank : 29)
Query Neighborhood Hits	77	Target Neighborhood Hits	124	Shared Neighborhood Hits	26
SwissProt Accessions	P46060	Gene names	RANGAP1
Domain Architecture
Description	Ran GTPase-activating protein 1.

RGP1_MOUSE
NC score	0.396021 (rank : 30)	θ value	6.43352e-06 (rank : 33)
Query Neighborhood Hits	77	Target Neighborhood Hits	105	Shared Neighborhood Hits	26
SwissProt Accessions	P46061, Q60801	Gene names	Rangap1, Fug1
Domain Architecture
Description	Ran GTPase-activating protein 1.

CAR12_HUMAN
NC score	0.386019 (rank : 31)	θ value	4.1701e-05 (rank : 36)
Query Neighborhood Hits	77	Target Neighborhood Hits	132	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NPP4, Q96J81, Q96J82, Q96J83	Gene names	CARD12, CLAN, CLAN1
Domain Architecture
Description	Caspase recruitment domain-containing protein 12 (Ice protease- activating factor) (Ipaf) (CARD, LRR, and NACHT-containing protein) (Clan protein).

BIRC1_HUMAN
NC score	0.269204 (rank : 32)	θ value	0.00134147 (rank : 39)
Query Neighborhood Hits	77	Target Neighborhood Hits	61	Shared Neighborhood Hits	30
SwissProt Accessions	Q13075, O75857, Q13730, Q99796	Gene names	BIRC1, NAIP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein).

BIR1F_MOUSE
NC score	0.258514 (rank : 33)	θ value	6.43352e-06 (rank : 32)
Query Neighborhood Hits	77	Target Neighborhood Hits	88	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JIB6, O09121, O09122, P81704	Gene names	Birc1f, Naip-rs4, Naip6
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).

BIR1B_MOUSE
NC score	0.255486 (rank : 34)	θ value	8.40245e-06 (rank : 34)
Query Neighborhood Hits	77	Target Neighborhood Hits	93	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QUK4, O09124, Q9R030	Gene names	Birc1b, Naip-rs6, Naip2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2).

BIR1A_MOUSE
NC score	0.255118 (rank : 35)	θ value	0.000602161 (rank : 38)
Query Neighborhood Hits	77	Target Neighborhood Hits	94	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QWK5, Q9JIB5, Q9R017	Gene names	Birc1a, Naip, Naip1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1).

BIR1G_MOUSE
NC score	0.252205 (rank : 36)	θ value	3.19293e-05 (rank : 35)
Query Neighborhood Hits	77	Target Neighborhood Hits	92	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JIB3	Gene names	Birc1g, Naip7
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).

BIR1E_MOUSE
NC score	0.251053 (rank : 37)	θ value	7.1131e-05 (rank : 37)
Query Neighborhood Hits	77	Target Neighborhood Hits	93	Shared Neighborhood Hits	30
SwissProt Accessions	Q9R016, O09121, O09122, P81703, Q9R029	Gene names	Birc1e, Naip-rs3, Naip5
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).

LRC45_MOUSE
NC score	0.242088 (rank : 38)	θ value	2.69671e-12 (rank : 24)
Query Neighborhood Hits	77	Target Neighborhood Hits	959	Shared Neighborhood Hits	40
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRC45_HUMAN
NC score	0.237036 (rank : 39)	θ value	2.20605e-14 (rank : 21)
Query Neighborhood Hits	77	Target Neighborhood Hits	933	Shared Neighborhood Hits	36
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

TMOD1_MOUSE
NC score	0.234633 (rank : 40)	θ value	4.92598e-06 (rank : 31)
Query Neighborhood Hits	77	Target Neighborhood Hits	28	Shared Neighborhood Hits	19
SwissProt Accessions	P49813, Q9ERR9	Gene names	Tmod1, Tmod
Domain Architecture
Description	Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod).

TMOD1_HUMAN
NC score	0.233639 (rank : 41)	θ value	3.77169e-06 (rank : 30)
Query Neighborhood Hits	77	Target Neighborhood Hits	32	Shared Neighborhood Hits	20
SwissProt Accessions	P28289, Q9BUF1	Gene names	TMOD1, TMOD
Domain Architecture
Description	Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod).

TMOD2_HUMAN
NC score	0.231046 (rank : 42)	θ value	0.00298849 (rank : 41)
Query Neighborhood Hits	77	Target Neighborhood Hits	29	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZR1	Gene names	TMOD2, NTMOD
Domain Architecture
Description	Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod).

TMOD4_HUMAN
NC score	0.218528 (rank : 43)	θ value	0.00298849 (rank : 42)
Query Neighborhood Hits	77	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZQ9, Q8WVL3, Q9UKH2	Gene names	TMOD4
Domain Architecture
Description	Tropomodulin-4 (Skeletal muscle tropomodulin) (Sk-Tmod).

TMOD3_MOUSE
NC score	0.217555 (rank : 44)	θ value	0.0330416 (rank : 45)
Query Neighborhood Hits	77	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JHJ0, Q3TIT1	Gene names	Tmod3
Domain Architecture
Description	Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod).

TMOD4_MOUSE
NC score	0.215985 (rank : 45)	θ value	0.00228821 (rank : 40)
Query Neighborhood Hits	77	Target Neighborhood Hits	36	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JLH8	Gene names	Tmod4
Domain Architecture
Description	Tropomodulin-4 (Skeletal muscle tropomodulin) (Sk-Tmod).

TMOD3_HUMAN
NC score	0.214543 (rank : 46)	θ value	0.0148317 (rank : 44)
Query Neighborhood Hits	77	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NYL9, Q9NT43, Q9NZR0	Gene names	TMOD3
Domain Architecture
Description	Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod).

LMD1_HUMAN
NC score	0.208763 (rank : 47)	θ value	0.125558 (rank : 49)
Query Neighborhood Hits	77	Target Neighborhood Hits	169	Shared Neighborhood Hits	17
SwissProt Accessions	P29536	Gene names	LMOD1
Domain Architecture
Description	Leiomodin-1 (Leiomodin, muscle form) (64 kDa autoantigen D1) (64 kDa autoantigen 1D) (64 kDa autoantigen 1D3) (Thyroid-associated ophthalmopathy autoantigen) (Smooth muscle leiomodin) (SM-Lmod).

TMOD2_MOUSE
NC score	0.206441 (rank : 48)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	77	Target Neighborhood Hits	41	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JKK7, Q9JLH9	Gene names	Tmod2
Domain Architecture
Description	Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod).

ASC_MOUSE
NC score	0.162638 (rank : 49)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	77	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	Q9EPB4, Q9D2W9	Gene names	Pycard, Asc
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein).

ASC_HUMAN
NC score	0.139611 (rank : 50)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	77	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ULZ3, Q96D12, Q9BSZ5, Q9HBD0, Q9NXJ8	Gene names	PYCARD, ASC, CARD5, TMS1
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (hASC) (PYD and CARD domain-containing protein) (Target of methylation-induced silencing 1) (Caspase recruitment domain-containing protein 5).

NOL3_HUMAN
NC score	0.119969 (rank : 51)	θ value	0.62314 (rank : 53)
Query Neighborhood Hits	77	Target Neighborhood Hits	49	Shared Neighborhood Hits	7
SwissProt Accessions	O60936, O60937	Gene names	NOL3, ARC, NOP
Domain Architecture
Description	Nucleolar protein 3 (Apoptosis repressor with CARD) (Muscle-enriched cytoplasmic protein) (Myp) (Nucleolar protein of 30 kDa) (Nop30).

NOL3_MOUSE
NC score	0.105941 (rank : 52)	θ value	1.06291 (rank : 58)
Query Neighborhood Hits	77	Target Neighborhood Hits	97	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D1X0	Gene names	Nol3
Domain Architecture
Description	Nucleolar protein 3.

BIRC2_MOUSE
NC score	0.086336 (rank : 53)	θ value	1.38821 (rank : 59)
Query Neighborhood Hits	77	Target Neighborhood Hits	137	Shared Neighborhood Hits	15
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

MEFV_MOUSE
NC score	0.084297 (rank : 54)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	77	Target Neighborhood Hits	236	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

CARD8_HUMAN
NC score	0.083740 (rank : 55)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	77	Target Neighborhood Hits	22	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y2G2, Q6PGP8, Q96P82	Gene names	CARD8, KIAA0955, NDPP1
Domain Architecture
Description	Caspase recruitment domain-containing protein 8 (Apoptotic protein NDPP1) (DACAR) (CARD-inhibitor of NF-kappa-B-activating ligand) (CARDINAL) (Tumor-up-regulated CARD-containing antagonist of CASP9) (TUCAN).

BIRC2_HUMAN
NC score	0.079426 (rank : 56)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	77	Target Neighborhood Hits	142	Shared Neighborhood Hits	14
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

BIRC4_MOUSE
NC score	0.066682 (rank : 57)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	77	Target Neighborhood Hits	89	Shared Neighborhood Hits	8
SwissProt Accessions	Q60989, O08865	Gene names	Birc4, Aipa, Api3, Miha, Xiap
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3).

BIRC3_HUMAN
NC score	0.066281 (rank : 58)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	77	Target Neighborhood Hits	133	Shared Neighborhood Hits	12
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

BIRC4_HUMAN
NC score	0.065525 (rank : 59)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	77	Target Neighborhood Hits	89	Shared Neighborhood Hits	8
SwissProt Accessions	P98170, Q9NQ14	Gene names	BIRC4, API3, IAP3, XIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP).

BIRC3_MOUSE
NC score	0.064627 (rank : 60)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	77	Target Neighborhood Hits	113	Shared Neighborhood Hits	9
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

LRC41_HUMAN
NC score	0.064375 (rank : 61)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	77	Target Neighborhood Hits	51	Shared Neighborhood Hits	17
SwissProt Accessions	Q15345, Q71RA8, Q9BSM0	Gene names	LRRC41, MUF1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 41 (Protein Muf1).

LRC41_MOUSE
NC score	0.063149 (rank : 62)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	77	Target Neighborhood Hits	37	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K1C9, Q91VX4	Gene names	Lrrc41, Muf1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 41 (Protein Muf1).

LRC14_HUMAN
NC score	0.062976 (rank : 63)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	77	Target Neighborhood Hits	57	Shared Neighborhood Hits	17
SwissProt Accessions	Q15048	Gene names	LRRC14, KIAA0014
Domain Architecture
Description	Leucine-rich repeat-containing protein 14.

BIRC5_HUMAN
NC score	0.060788 (rank : 64)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	77	Target Neighborhood Hits	20	Shared Neighborhood Hits	7
SwissProt Accessions	O15392, Q2I3N8, Q4VGX0, Q53F61, Q5MGC6, Q6FHL2, Q75SP2, Q9P2W8	Gene names	BIRC5, API4, IAP4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4).

LRC57_HUMAN
NC score	0.060143 (rank : 65)	θ value	0.0431538 (rank : 46)
Query Neighborhood Hits	77	Target Neighborhood Hits	271	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N9N7, Q7Z2Z6, Q8N1T6	Gene names	LRRC57
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 57.

BIRC5_MOUSE
NC score	0.059878 (rank : 66)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	77	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	O70201, Q923F7, Q9WU53, Q9WU54	Gene names	Birc5, Api4, Iap4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4) (TIAP).

BIRC7_HUMAN
NC score	0.059061 (rank : 67)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	77	Target Neighborhood Hits	185	Shared Neighborhood Hits	8
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

CARD6_HUMAN
NC score	0.055612 (rank : 68)	θ value	1.06291 (rank : 56)
Query Neighborhood Hits	77	Target Neighborhood Hits	145	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BX69	Gene names	CARD6
Domain Architecture
Description	Caspase recruitment domain-containing protein 6.

ICBR_HUMAN
NC score	0.055235 (rank : 69)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	77	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	P57730	Gene names	ICEBERG
Domain Architecture
Description	Caspase-1 inhibitor Iceberg.

LRC57_MOUSE
NC score	0.055231 (rank : 70)	θ value	0.0961366 (rank : 48)
Query Neighborhood Hits	77	Target Neighborhood Hits	267	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D1G5, Q9DC95	Gene names	Lrrc57
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 57.

LRC47_MOUSE
NC score	0.054893 (rank : 71)	θ value	0.47712 (rank : 51)
Query Neighborhood Hits	77	Target Neighborhood Hits	299	Shared Neighborhood Hits	23
SwissProt Accessions	Q505F5, Q3U380, Q6ZPW2, Q9CUZ0	Gene names	Lrrc47, Kiaa1185
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 47.

BIRC8_HUMAN
NC score	0.053829 (rank : 72)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	77	Target Neighborhood Hits	121	Shared Neighborhood Hits	8
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

LRC47_HUMAN
NC score	0.048748 (rank : 73)	θ value	0.21417 (rank : 50)
Query Neighborhood Hits	77	Target Neighborhood Hits	300	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N1G4, Q9ULN5	Gene names	LRRC47, KIAA1185
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 47.

LAP4_MOUSE
NC score	0.030582 (rank : 74)	θ value	0.0736092 (rank : 47)
Query Neighborhood Hits	77	Target Neighborhood Hits	590	Shared Neighborhood Hits	20
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

LRC8A_HUMAN
NC score	0.028542 (rank : 75)	θ value	1.06291 (rank : 57)
Query Neighborhood Hits	77	Target Neighborhood Hits	274	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IWT6, Q6UXM2, Q8NCI0, Q9P2B1	Gene names	LRRC8A, KIAA1437, LRRC8
Domain Architecture
Description	Leucine-rich repeat-containing protein 8A.

LRC8A_MOUSE
NC score	0.027867 (rank : 76)	θ value	1.38821 (rank : 61)
Query Neighborhood Hits	77	Target Neighborhood Hits	274	Shared Neighborhood Hits	21
SwissProt Accessions	Q80WG5	Gene names	Lrrc8a, Lrrc8
Domain Architecture
Description	Leucine-rich repeat-containing protein 8A.

CASP1_MOUSE
NC score	0.027474 (rank : 77)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	77	Target Neighborhood Hits	38	Shared Neighborhood Hits	10
SwissProt Accessions	P29452	Gene names	Casp1, Il1bc
Domain Architecture
Description	Caspase-1 precursor (EC 3.4.22.36) (CASP-1) (Interleukin-1 beta convertase) (IL-1BC) (IL-1 beta-converting enzyme) (ICE) (Interleukin- 1 beta-converting enzyme) (p45) [Contains: Caspase-1 p20 subunit; Caspase-1 p10 subunit].

PGS2_MOUSE
NC score	0.024468 (rank : 78)	θ value	0.813845 (rank : 55)
Query Neighborhood Hits	77	Target Neighborhood Hits	285	Shared Neighborhood Hits	18
SwissProt Accessions	P28654	Gene names	Dcn
Domain Architecture
Description	Decorin precursor (Bone proteoglycan II) (PG-S2) (PG40).

LLR1_HUMAN
NC score	0.023221 (rank : 79)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	77	Target Neighborhood Hits	225	Shared Neighborhood Hits	15
SwissProt Accessions	Q96L50, Q86SZ1, Q8N6H9	Gene names	PPIL5, LRR1
Domain Architecture
Description	Peptidylprolyl isomerase-like 5 (LRR-repeat protein 1) (LRR-1) (4-1BB- mediated signaling molecule) (4-1BBlrr).

RAVR1_HUMAN
NC score	0.022380 (rank : 80)	θ value	0.62314 (rank : 54)
Query Neighborhood Hits	77	Target Neighborhood Hits	159	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IY67, Q8IY60, Q8TF24	Gene names	RAVER1, KIAA1978
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 1 (Protein raver-1).

CASP1_HUMAN
NC score	0.021673 (rank : 81)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	77	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	P29466, Q9UCN3	Gene names	CASP1, IL1BC, IL1BCE
Domain Architecture
Description	Caspase-1 precursor (EC 3.4.22.36) (CASP-1) (Interleukin-1 beta convertase) (IL-1BC) (IL-1 beta-converting enzyme) (ICE) (Interleukin- 1 beta-converting enzyme) (p45) [Contains: Caspase-1 p20 subunit; Caspase-1 p10 subunit].

LRFN4_HUMAN
NC score	0.018991 (rank : 82)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	77	Target Neighborhood Hits	462	Shared Neighborhood Hits	17
SwissProt Accessions	Q6PJG9, Q9BWJ0	Gene names	LRFN4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

LRSM1_HUMAN
NC score	0.018563 (rank : 83)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	77	Target Neighborhood Hits	1078	Shared Neighborhood Hits	17
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

RAVR1_MOUSE
NC score	0.017907 (rank : 84)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	77	Target Neighborhood Hits	179	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CW46, Q5DTT6, Q811K0, Q8C3Z1, Q8CA14	Gene names	Raver1, Kiaa1978
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 1 (Protein raver-1).

LRFN4_MOUSE
NC score	0.014629 (rank : 85)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	77	Target Neighborhood Hits	442	Shared Neighborhood Hits	15
SwissProt Accessions	Q80XU8, Q3TQG8, Q8K3C4	Gene names	Lrfn4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

LRIG3_HUMAN
NC score	0.014590 (rank : 86)	θ value	0.47712 (rank : 52)
Query Neighborhood Hits	77	Target Neighborhood Hits	601	Shared Neighborhood Hits	17
SwissProt Accessions	Q6UXM1, Q6UXL7, Q8NC72	Gene names	LRIG3, LIG3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor (LIG-3).

DIRA3_HUMAN
NC score	0.014334 (rank : 87)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	77	Target Neighborhood Hits	241	Shared Neighborhood Hits	9
SwissProt Accessions	O95661	Gene names	DIRAS3, ARHI, NOEY2, RHOI
Domain Architecture
Description	GTP-binding protein Di-Ras3 (Distinct subgroup of the Ras family member 3) (Rho-related GTP-binding protein RhoI).

LRIG2_MOUSE
NC score	0.014301 (rank : 88)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	77	Target Neighborhood Hits	586	Shared Neighborhood Hits	18
SwissProt Accessions	Q52KR2, Q69ZY8	Gene names	Lrig2, Kiaa0806
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor.

P3H2_HUMAN
NC score	0.010516 (rank : 89)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	77	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IVL5, Q9NVI2	Gene names	LEPREL1, MLAT4, P3H2
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 2 precursor (EC 1.14.11.7) (Leprecan-like protein 1) (Myxoid liposarcoma-associated protein 4).

OSBL3_MOUSE
NC score	0.003687 (rank : 90)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	77	Target Neighborhood Hits	86	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

RHOD_HUMAN
NC score	0.001485 (rank : 91)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	77	Target Neighborhood Hits	262	Shared Neighborhood Hits	4
SwissProt Accessions	O00212	Gene names	RHOD, ARHD
Domain Architecture
Description	Rho-related GTP-binding protein RhoD precursor (Rho-related protein HP1) (RhoHP1).

RAB26_MOUSE
NC score	0.000242 (rank : 92)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	77	Target Neighborhood Hits	287	Shared Neighborhood Hits	4
SwissProt Accessions	Q504M8	Gene names	Rab26
Domain Architecture	No domain graphic available
Description	Ras-related protein Rab-26.