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Network neighborhood for query Sequence : LRC34_MOUSE

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LRC34_MOUSE
SwissProt Accessions	Q9DAM1	Gene names	Lrrc34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

LRC34_MOUSE
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	58	Target Neighborhood Hits	58	Shared Neighborhood Hits	58
SwissProt Accessions	Q9DAM1	Gene names	Lrrc34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

LRC34_HUMAN
θ value	1.15832e-164 (rank : 2)	NC score	0.975389 (rank : 2)
Query Neighborhood Hits	58	Target Neighborhood Hits	67	Shared Neighborhood Hits	44
SwissProt Accessions	Q8IZ02	Gene names	LRRC34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

CARD4_HUMAN
θ value	7.58209e-15 (rank : 3)	NC score	0.643847 (rank : 3)
Query Neighborhood Hits	58	Target Neighborhood Hits	102	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y239, Q8IWF5	Gene names	CARD4, NOD1
Domain Architecture
Description	Caspase recruitment domain-containing protein 4 (Protein Nod1).

CARD4_MOUSE
θ value	9.90251e-15 (rank : 4)	NC score	0.638140 (rank : 4)
Query Neighborhood Hits	58	Target Neighborhood Hits	85	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BHB0, Q8BUT6	Gene names	Card4
Domain Architecture
Description	Caspase recruitment domain-containing protein 4.

LRC45_MOUSE
θ value	1.33837e-11 (rank : 5)	NC score	0.271622 (rank : 31)
Query Neighborhood Hits	58	Target Neighborhood Hits	959	Shared Neighborhood Hits	36
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

NALP4_HUMAN
θ value	1.133e-10 (rank : 6)	NC score	0.535279 (rank : 10)
Query Neighborhood Hits	58	Target Neighborhood Hits	81	Shared Neighborhood Hits	33
SwissProt Accessions	Q96MN2, Q86W87, Q96AY6	Gene names	NALP4, PAN2, PYPAF4, RNH2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 4 (PYRIN-containing APAF1-like protein 4) (PAAD and NACHT-containing protein 2) (PYRIN and NACHT- containing protein 2) (Ribonuclease inhibitor 2).

LRC45_HUMAN
θ value	4.30538e-10 (rank : 7)	NC score	0.255124 (rank : 32)
Query Neighborhood Hits	58	Target Neighborhood Hits	933	Shared Neighborhood Hits	33
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

NAL13_HUMAN
θ value	3.64472e-09 (rank : 8)	NC score	0.546233 (rank : 9)
Query Neighborhood Hits	58	Target Neighborhood Hits	93	Shared Neighborhood Hits	33
SwissProt Accessions	Q86W25, Q7RTR5	Gene names	NALP13, NOD14
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 13 (Nucleotide-binding oligomerization domain protein 14).

RINI_MOUSE
θ value	6.21693e-09 (rank : 9)	NC score	0.606194 (rank : 5)
Query Neighborhood Hits	58	Target Neighborhood Hits	87	Shared Neighborhood Hits	35
SwissProt Accessions	Q91VI7, Q924P4	Gene names	Rnh1, Rnh
Domain Architecture	No domain graphic available
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1).

RINI_HUMAN
θ value	1.06045e-08 (rank : 10)	NC score	0.593435 (rank : 8)
Query Neighborhood Hits	58	Target Neighborhood Hits	78	Shared Neighborhood Hits	38
SwissProt Accessions	P13489	Gene names	RNH1, PRI, RNH
Domain Architecture
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1) (RAI) (Placental ribonuclease inhibitor) (RNase inhibitor) (RI).

CAR15_MOUSE
θ value	1.80886e-08 (rank : 11)	NC score	0.593499 (rank : 7)
Query Neighborhood Hits	58	Target Neighborhood Hits	93	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K3Z0	Gene names	Card15, Nod2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2).

CAR15_HUMAN
θ value	2.36244e-08 (rank : 12)	NC score	0.596688 (rank : 6)
Query Neighborhood Hits	58	Target Neighborhood Hits	77	Shared Neighborhood Hits	36
SwissProt Accessions	Q9HC29, Q96RH5, Q96RH6, Q96RH8	Gene names	CARD15, IBD1, NOD2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2) (Inflammatory bowel disease protein 1).

NALP2_HUMAN
θ value	6.87365e-08 (rank : 13)	NC score	0.526705 (rank : 12)
Query Neighborhood Hits	58	Target Neighborhood Hits	65	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NX02, Q53FL5, Q59G09, Q8IXT0, Q9BVN5, Q9H6G6, Q9HAV9, Q9NWK3	Gene names	NALP2, NBS1, PAN1, PYPAF2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 2 (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2) (Nucleotide-binding site protein 1).

CIAS1_MOUSE
θ value	1.53129e-07 (rank : 14)	NC score	0.519022 (rank : 15)
Query Neighborhood Hits	58	Target Neighborhood Hits	67	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R4B8, Q6JEL0	Gene names	Cias1, Mmig1, Nalp3, Pypaf1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein homolog (PYRIN-containing APAF1-like protein 1) (Mast cell maturation-associated-inducible protein 1) (Cryopyrin).

NALP5_MOUSE
θ value	5.81887e-07 (rank : 15)	NC score	0.493484 (rank : 20)
Query Neighborhood Hits	58	Target Neighborhood Hits	560	Shared Neighborhood Hits	30
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

RGP1_HUMAN
θ value	9.92553e-07 (rank : 16)	NC score	0.463473 (rank : 22)
Query Neighborhood Hits	58	Target Neighborhood Hits	124	Shared Neighborhood Hits	26
SwissProt Accessions	P46060	Gene names	RANGAP1
Domain Architecture
Description	Ran GTPase-activating protein 1.

NAL14_HUMAN
θ value	2.21117e-06 (rank : 17)	NC score	0.525908 (rank : 13)
Query Neighborhood Hits	58	Target Neighborhood Hits	76	Shared Neighborhood Hits	31
SwissProt Accessions	Q86W24, Q7RTR6	Gene names	NALP14, NOD5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 14 (Nucleotide-binding oligomerization domain protein 5).

CIAS1_HUMAN
θ value	2.88788e-06 (rank : 18)	NC score	0.512051 (rank : 17)
Query Neighborhood Hits	58	Target Neighborhood Hits	76	Shared Neighborhood Hits	30
SwissProt Accessions	Q96P20, O75434, Q59H68, Q5JQS8, Q5JQS9, Q6TG35, Q8TCW0, Q8TEU9, Q8WXH9	Gene names	CIAS1, NALP3, PYPAF1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein (Cryopyrin) (NACHT-, LRR- and PYD-containing protein 3) (PYRIN-containing APAF1-like protein 1) (Angiotensin/vasopressin receptor AII/AVP-like).

NAL12_HUMAN
θ value	2.88788e-06 (rank : 19)	NC score	0.517239 (rank : 16)
Query Neighborhood Hits	58	Target Neighborhood Hits	96	Shared Neighborhood Hits	31
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

RGP1_MOUSE
θ value	2.88788e-06 (rank : 20)	NC score	0.439387 (rank : 23)
Query Neighborhood Hits	58	Target Neighborhood Hits	105	Shared Neighborhood Hits	26
SwissProt Accessions	P46061, Q60801	Gene names	Rangap1, Fug1
Domain Architecture
Description	Ran GTPase-activating protein 1.

NALP7_HUMAN
θ value	2.44474e-05 (rank : 21)	NC score	0.505973 (rank : 18)
Query Neighborhood Hits	58	Target Neighborhood Hits	65	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WX94, Q7RTR1	Gene names	NALP7, NOD12, PYPAF3
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 7 (PYRIN-containing APAF1-like protein 3).

NALP1_HUMAN
θ value	7.1131e-05 (rank : 22)	NC score	0.471373 (rank : 21)
Query Neighborhood Hits	58	Target Neighborhood Hits	138	Shared Neighborhood Hits	32
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

NALP5_HUMAN
θ value	0.000158464 (rank : 23)	NC score	0.520988 (rank : 14)
Query Neighborhood Hits	58	Target Neighborhood Hits	88	Shared Neighborhood Hits	30
SwissProt Accessions	P59047, Q86W29	Gene names	NALP5, MATER
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Mater protein homolog).

LRC31_HUMAN
θ value	0.00175202 (rank : 24)	NC score	0.428875 (rank : 24)
Query Neighborhood Hits	58	Target Neighborhood Hits	139	Shared Neighborhood Hits	33
SwissProt Accessions	Q6UY01, Q8N848, Q9H5N5	Gene names	LRRC31
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 31.

NAL11_HUMAN
θ value	0.00298849 (rank : 25)	NC score	0.494649 (rank : 19)
Query Neighborhood Hits	58	Target Neighborhood Hits	66	Shared Neighborhood Hits	33
SwissProt Accessions	P59045, Q53ZZ0, Q8NBF5	Gene names	NALP11, NOD17, PYPAF6
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 11 (PYRIN-containing APAF1-like protein 6) (Nucleotide-binding oligomerization domain protein 17).

CF154_HUMAN
θ value	0.00665767 (rank : 26)	NC score	0.530398 (rank : 11)
Query Neighborhood Hits	58	Target Neighborhood Hits	36	Shared Neighborhood Hits	28
SwissProt Accessions	Q5JTD7	Gene names	C6orf154
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf154.

C2TA_MOUSE
θ value	0.0193708 (rank : 27)	NC score	0.406229 (rank : 25)
Query Neighborhood Hits	58	Target Neighborhood Hits	131	Shared Neighborhood Hits	35
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).

C2TA_HUMAN
θ value	0.0736092 (rank : 28)	NC score	0.385711 (rank : 28)
Query Neighborhood Hits	58	Target Neighborhood Hits	190	Shared Neighborhood Hits	31
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

TMOD4_HUMAN
θ value	0.125558 (rank : 29)	NC score	0.156866 (rank : 35)
Query Neighborhood Hits	58	Target Neighborhood Hits	37	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZQ9, Q8WVL3, Q9UKH2	Gene names	TMOD4
Domain Architecture
Description	Tropomodulin-4 (Skeletal muscle tropomodulin) (Sk-Tmod).

LMD1_HUMAN
θ value	0.163984 (rank : 30)	NC score	0.159364 (rank : 34)
Query Neighborhood Hits	58	Target Neighborhood Hits	169	Shared Neighborhood Hits	14
SwissProt Accessions	P29536	Gene names	LMOD1
Domain Architecture
Description	Leiomodin-1 (Leiomodin, muscle form) (64 kDa autoantigen D1) (64 kDa autoantigen 1D) (64 kDa autoantigen 1D3) (Thyroid-associated ophthalmopathy autoantigen) (Smooth muscle leiomodin) (SM-Lmod).

LRC41_MOUSE
θ value	0.21417 (rank : 31)	NC score	0.145580 (rank : 37)
Query Neighborhood Hits	58	Target Neighborhood Hits	37	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K1C9, Q91VX4	Gene names	Lrrc41, Muf1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 41 (Protein Muf1).

TMOD4_MOUSE
θ value	0.279714 (rank : 32)	NC score	0.147008 (rank : 36)
Query Neighborhood Hits	58	Target Neighborhood Hits	36	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JLH8	Gene names	Tmod4
Domain Architecture
Description	Tropomodulin-4 (Skeletal muscle tropomodulin) (Sk-Tmod).

TLR4_HUMAN
θ value	0.365318 (rank : 33)	NC score	0.037168 (rank : 54)
Query Neighborhood Hits	58	Target Neighborhood Hits	298	Shared Neighborhood Hits	16
SwissProt Accessions	O00206, Q9UK78, Q9UM57	Gene names	TLR4
Domain Architecture
Description	Toll-like receptor 4 precursor (hToll) (CD284 antigen).

LRC41_HUMAN
θ value	0.47712 (rank : 34)	NC score	0.136348 (rank : 38)
Query Neighborhood Hits	58	Target Neighborhood Hits	51	Shared Neighborhood Hits	16
SwissProt Accessions	Q15345, Q71RA8, Q9BSM0	Gene names	LRRC41, MUF1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 41 (Protein Muf1).

TMOD1_HUMAN
θ value	0.47712 (rank : 35)	NC score	0.133341 (rank : 39)
Query Neighborhood Hits	58	Target Neighborhood Hits	32	Shared Neighborhood Hits	18
SwissProt Accessions	P28289, Q9BUF1	Gene names	TMOD1, TMOD
Domain Architecture
Description	Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod).

LGR5_HUMAN
θ value	0.62314 (rank : 36)	NC score	0.023795 (rank : 62)
Query Neighborhood Hits	58	Target Neighborhood Hits	452	Shared Neighborhood Hits	20
SwissProt Accessions	O75473, Q9UP75	Gene names	LGR5, GPR49, GPR67
Domain Architecture
Description	Leucine-rich repeat-containing G-protein coupled receptor 5 precursor (Orphan G-protein coupled receptor HG38) (G-protein coupled receptor 49) (G-protein coupled receptor 67).

ATP9B_HUMAN
θ value	0.813845 (rank : 37)	NC score	0.032629 (rank : 58)
Query Neighborhood Hits	58	Target Neighborhood Hits	71	Shared Neighborhood Hits	5
SwissProt Accessions	O43861, O60872	Gene names	ATP9B, ATPIIB, NEO1L
Domain Architecture	No domain graphic available
Description	Probable phospholipid-transporting ATPase IIB (EC 3.6.3.1).

LRC14_HUMAN
θ value	0.813845 (rank : 38)	NC score	0.081140 (rank : 45)
Query Neighborhood Hits	58	Target Neighborhood Hits	57	Shared Neighborhood Hits	16
SwissProt Accessions	Q15048	Gene names	LRRC14, KIAA0014
Domain Architecture
Description	Leucine-rich repeat-containing protein 14.

ATP9A_HUMAN
θ value	1.06291 (rank : 39)	NC score	0.034202 (rank : 56)
Query Neighborhood Hits	58	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	O75110, Q5TFW5, Q5TFW6, Q5TFW9, Q6ZMF3, Q9NQK6, Q9NQK7	Gene names	ATP9A, ATPIIA, KIAA0611
Domain Architecture	No domain graphic available
Description	Probable phospholipid-transporting ATPase IIA (EC 3.6.3.1) (ATPase class II type 9A) (ATPase IIA).

ATP9A_MOUSE
θ value	1.38821 (rank : 40)	NC score	0.034094 (rank : 57)
Query Neighborhood Hits	58	Target Neighborhood Hits	61	Shared Neighborhood Hits	5
SwissProt Accessions	O70228, Q8VDI5, Q922L9	Gene names	Atp9a
Domain Architecture	No domain graphic available
Description	Probable phospholipid-transporting ATPase IIA (EC 3.6.3.1) (ATPase class II type 9A).

LRC33_MOUSE
θ value	1.38821 (rank : 41)	NC score	0.036082 (rank : 55)
Query Neighborhood Hits	58	Target Neighborhood Hits	296	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BMT4, Q3TIA8, Q8BTT4, Q8BUI7, Q8BY16, Q8R063	Gene names	Lrrc33
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 33 precursor.

PDE5A_MOUSE
θ value	1.38821 (rank : 42)	NC score	0.021216 (rank : 67)
Query Neighborhood Hits	58	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CG03	Gene names	Pde5a, Pde5
Domain Architecture
Description	cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (CGB-PDE) (cGMP-binding cGMP-specific phosphodiesterase).

IP3KA_HUMAN
θ value	1.81305 (rank : 43)	NC score	0.022788 (rank : 65)
Query Neighborhood Hits	58	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	P23677, Q8TAN3	Gene names	ITPKA
Domain Architecture
Description	Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase A) (IP3K A) (IP3 3-kinase A).

PDE5A_HUMAN
θ value	1.81305 (rank : 44)	NC score	0.020772 (rank : 68)
Query Neighborhood Hits	58	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	O76074, O75026, O75887, Q86UI0, Q86V66, Q9Y6Z6	Gene names	PDE5A, PDE5
Domain Architecture
Description	cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (CGB-PDE) (cGMP-binding cGMP-specific phosphodiesterase).

LRC8C_HUMAN
θ value	2.36792 (rank : 45)	NC score	0.023785 (rank : 63)
Query Neighborhood Hits	58	Target Neighborhood Hits	255	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TDW0, Q9H075	Gene names	LRRC8C, AD158
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8C (Protein AD158).

NALP6_MOUSE
θ value	2.36792 (rank : 46)	NC score	0.399470 (rank : 26)
Query Neighborhood Hits	58	Target Neighborhood Hits	55	Shared Neighborhood Hits	25
SwissProt Accessions	Q91WS2, Q8K0L4	Gene names	Nalp6, Pypaf5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5-like).

TMOD1_MOUSE
θ value	2.36792 (rank : 47)	NC score	0.128653 (rank : 40)
Query Neighborhood Hits	58	Target Neighborhood Hits	28	Shared Neighborhood Hits	17
SwissProt Accessions	P49813, Q9ERR9	Gene names	Tmod1, Tmod
Domain Architecture
Description	Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod).

DICER_HUMAN
θ value	3.0926 (rank : 48)	NC score	0.023630 (rank : 64)
Query Neighborhood Hits	58	Target Neighborhood Hits	126	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

PIDD_MOUSE
θ value	3.0926 (rank : 49)	NC score	0.025592 (rank : 60)
Query Neighborhood Hits	58	Target Neighborhood Hits	256	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ERV7	Gene names	Lrdd, Pidd
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and death domain-containing protein.

FMOD_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.015015 (rank : 70)
Query Neighborhood Hits	58	Target Neighborhood Hits	283	Shared Neighborhood Hits	13
SwissProt Accessions	Q06828, Q15331	Gene names	FMOD, FM
Domain Architecture
Description	Fibromodulin precursor (FM) (Collagen-binding 59 kDa protein) (Keratan sulfate proteoglycan fibromodulin) (KSPG fibromodulin).

LRC8C_MOUSE
θ value	5.27518 (rank : 51)	NC score	0.022094 (rank : 66)
Query Neighborhood Hits	58	Target Neighborhood Hits	242	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R502, Q3TEP9, Q8C296, Q8R0N7, Q8R3G5	Gene names	Lrrc8c, Ad158
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8C (Protein AD158).

PP1R7_MOUSE
θ value	5.27518 (rank : 52)	NC score	0.027387 (rank : 59)
Query Neighborhood Hits	58	Target Neighborhood Hits	256	Shared Neighborhood Hits	15
SwissProt Accessions	Q3UM45, Q9CV31, Q9Z105	Gene names	Ppp1r7, Sds22
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22).

TMOD2_MOUSE
θ value	5.27518 (rank : 53)	NC score	0.115812 (rank : 43)
Query Neighborhood Hits	58	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JKK7, Q9JLH9	Gene names	Tmod2
Domain Architecture
Description	Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod).

TLR8_HUMAN
θ value	6.88961 (rank : 54)	NC score	0.025172 (rank : 61)
Query Neighborhood Hits	58	Target Neighborhood Hits	298	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NR97, Q6UXL6, Q9NYG9	Gene names	TLR8
Domain Architecture
Description	Toll-like receptor 8 precursor.

ANM3_HUMAN
θ value	8.99809 (rank : 55)	NC score	0.007329 (rank : 73)
Query Neighborhood Hits	58	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	O60678	Gene names	PRMT3, HRMT1L3
Domain Architecture
Description	Protein arginine N-methyltransferase 3 (EC 2.1.1.-) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3).

FMOD_MOUSE
θ value	8.99809 (rank : 56)	NC score	0.015412 (rank : 69)
Query Neighborhood Hits	58	Target Neighborhood Hits	286	Shared Neighborhood Hits	14
SwissProt Accessions	P50608	Gene names	Fmod
Domain Architecture
Description	Fibromodulin precursor (FM) (Collagen-binding 59 kDa protein) (Keratan sulfate proteoglycan fibromodulin) (KSPG fibromodulin).

LR37A_HUMAN
θ value	8.99809 (rank : 57)	NC score	0.010993 (rank : 72)
Query Neighborhood Hits	58	Target Neighborhood Hits	720	Shared Neighborhood Hits	12
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

OMGP_HUMAN
θ value	8.99809 (rank : 58)	NC score	0.014339 (rank : 71)
Query Neighborhood Hits	58	Target Neighborhood Hits	268	Shared Neighborhood Hits	12
SwissProt Accessions	P23515	Gene names	OMG, OMGP
Domain Architecture
Description	Oligodendrocyte-myelin glycoprotein precursor.

ASC_HUMAN
θ value	θ > 10 (rank : 59)	NC score	0.062271 (rank : 51)
Query Neighborhood Hits	58	Target Neighborhood Hits	18	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ULZ3, Q96D12, Q9BSZ5, Q9HBD0, Q9NXJ8	Gene names	PYCARD, ASC, CARD5, TMS1
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (hASC) (PYD and CARD domain-containing protein) (Target of methylation-induced silencing 1) (Caspase recruitment domain-containing protein 5).

ASC_MOUSE
θ value	θ > 10 (rank : 60)	NC score	0.076864 (rank : 46)
Query Neighborhood Hits	58	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q9EPB4, Q9D2W9	Gene names	Pycard, Asc
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein).

BIR1A_MOUSE
θ value	θ > 10 (rank : 61)	NC score	0.064578 (rank : 49)
Query Neighborhood Hits	58	Target Neighborhood Hits	94	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QWK5, Q9JIB5, Q9R017	Gene names	Birc1a, Naip, Naip1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1).

BIR1B_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.062178 (rank : 52)
Query Neighborhood Hits	58	Target Neighborhood Hits	93	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QUK4, O09124, Q9R030	Gene names	Birc1b, Naip-rs6, Naip2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2).

BIR1E_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.062328 (rank : 50)
Query Neighborhood Hits	58	Target Neighborhood Hits	93	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R016, O09121, O09122, P81703, Q9R029	Gene names	Birc1e, Naip-rs3, Naip5
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).

BIR1F_MOUSE
θ value	θ > 10 (rank : 64)	NC score	0.064932 (rank : 48)
Query Neighborhood Hits	58	Target Neighborhood Hits	88	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JIB6, O09121, O09122, P81704	Gene names	Birc1f, Naip-rs4, Naip6
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).

BIR1G_MOUSE
θ value	θ > 10 (rank : 65)	NC score	0.061790 (rank : 53)
Query Neighborhood Hits	58	Target Neighborhood Hits	92	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JIB3	Gene names	Birc1g, Naip7
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).

BIRC1_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.076063 (rank : 47)
Query Neighborhood Hits	58	Target Neighborhood Hits	61	Shared Neighborhood Hits	19
SwissProt Accessions	Q13075, O75857, Q13730, Q99796	Gene names	BIRC1, NAIP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein).

CAR12_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.165518 (rank : 33)
Query Neighborhood Hits	58	Target Neighborhood Hits	132	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NPP4, Q96J81, Q96J82, Q96J83	Gene names	CARD12, CLAN, CLAN1
Domain Architecture
Description	Caspase recruitment domain-containing protein 12 (Ice protease- activating factor) (Ipaf) (CARD, LRR, and NACHT-containing protein) (Clan protein).

NAL10_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.350133 (rank : 29)
Query Neighborhood Hits	58	Target Neighborhood Hits	55	Shared Neighborhood Hits	19
SwissProt Accessions	Q86W26, Q6JGT0	Gene names	NALP10, NOD8, PYNOD
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10 (Nucleotide-binding oligomerization domain protein 8).

NAL10_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.345167 (rank : 30)
Query Neighborhood Hits	58	Target Neighborhood Hits	46	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CCN1	Gene names	Nalp10, Pynod
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10.

NALP6_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.390319 (rank : 27)
Query Neighborhood Hits	58	Target Neighborhood Hits	52	Shared Neighborhood Hits	24
SwissProt Accessions	P59044	Gene names	NALP6, PYPAF5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5).

TMOD2_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.120666 (rank : 41)
Query Neighborhood Hits	58	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NZR1	Gene names	TMOD2, NTMOD
Domain Architecture
Description	Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod).

TMOD3_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.109165 (rank : 44)
Query Neighborhood Hits	58	Target Neighborhood Hits	35	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NYL9, Q9NT43, Q9NZR0	Gene names	TMOD3
Domain Architecture
Description	Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod).

TMOD3_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.120079 (rank : 42)
Query Neighborhood Hits	58	Target Neighborhood Hits	34	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JHJ0, Q3TIT1	Gene names	Tmod3
Domain Architecture
Description	Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod).

Hits sorted by NC score

LRC34_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	58	Target Neighborhood Hits	58	Shared Neighborhood Hits	58
SwissProt Accessions	Q9DAM1	Gene names	Lrrc34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

LRC34_HUMAN
NC score	0.975389 (rank : 2)	θ value	1.15832e-164 (rank : 2)
Query Neighborhood Hits	58	Target Neighborhood Hits	67	Shared Neighborhood Hits	44
SwissProt Accessions	Q8IZ02	Gene names	LRRC34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

CARD4_HUMAN
NC score	0.643847 (rank : 3)	θ value	7.58209e-15 (rank : 3)
Query Neighborhood Hits	58	Target Neighborhood Hits	102	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y239, Q8IWF5	Gene names	CARD4, NOD1
Domain Architecture
Description	Caspase recruitment domain-containing protein 4 (Protein Nod1).

CARD4_MOUSE
NC score	0.638140 (rank : 4)	θ value	9.90251e-15 (rank : 4)
Query Neighborhood Hits	58	Target Neighborhood Hits	85	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BHB0, Q8BUT6	Gene names	Card4
Domain Architecture
Description	Caspase recruitment domain-containing protein 4.

RINI_MOUSE
NC score	0.606194 (rank : 5)	θ value	6.21693e-09 (rank : 9)
Query Neighborhood Hits	58	Target Neighborhood Hits	87	Shared Neighborhood Hits	35
SwissProt Accessions	Q91VI7, Q924P4	Gene names	Rnh1, Rnh
Domain Architecture	No domain graphic available
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1).

CAR15_HUMAN
NC score	0.596688 (rank : 6)	θ value	2.36244e-08 (rank : 12)
Query Neighborhood Hits	58	Target Neighborhood Hits	77	Shared Neighborhood Hits	36
SwissProt Accessions	Q9HC29, Q96RH5, Q96RH6, Q96RH8	Gene names	CARD15, IBD1, NOD2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2) (Inflammatory bowel disease protein 1).

CAR15_MOUSE
NC score	0.593499 (rank : 7)	θ value	1.80886e-08 (rank : 11)
Query Neighborhood Hits	58	Target Neighborhood Hits	93	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K3Z0	Gene names	Card15, Nod2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2).

RINI_HUMAN
NC score	0.593435 (rank : 8)	θ value	1.06045e-08 (rank : 10)
Query Neighborhood Hits	58	Target Neighborhood Hits	78	Shared Neighborhood Hits	38
SwissProt Accessions	P13489	Gene names	RNH1, PRI, RNH
Domain Architecture
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1) (RAI) (Placental ribonuclease inhibitor) (RNase inhibitor) (RI).

NAL13_HUMAN
NC score	0.546233 (rank : 9)	θ value	3.64472e-09 (rank : 8)
Query Neighborhood Hits	58	Target Neighborhood Hits	93	Shared Neighborhood Hits	33
SwissProt Accessions	Q86W25, Q7RTR5	Gene names	NALP13, NOD14
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 13 (Nucleotide-binding oligomerization domain protein 14).

NALP4_HUMAN
NC score	0.535279 (rank : 10)	θ value	1.133e-10 (rank : 6)
Query Neighborhood Hits	58	Target Neighborhood Hits	81	Shared Neighborhood Hits	33
SwissProt Accessions	Q96MN2, Q86W87, Q96AY6	Gene names	NALP4, PAN2, PYPAF4, RNH2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 4 (PYRIN-containing APAF1-like protein 4) (PAAD and NACHT-containing protein 2) (PYRIN and NACHT- containing protein 2) (Ribonuclease inhibitor 2).

CF154_HUMAN
NC score	0.530398 (rank : 11)	θ value	0.00665767 (rank : 26)
Query Neighborhood Hits	58	Target Neighborhood Hits	36	Shared Neighborhood Hits	28
SwissProt Accessions	Q5JTD7	Gene names	C6orf154
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf154.

NALP2_HUMAN
NC score	0.526705 (rank : 12)	θ value	6.87365e-08 (rank : 13)
Query Neighborhood Hits	58	Target Neighborhood Hits	65	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NX02, Q53FL5, Q59G09, Q8IXT0, Q9BVN5, Q9H6G6, Q9HAV9, Q9NWK3	Gene names	NALP2, NBS1, PAN1, PYPAF2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 2 (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2) (Nucleotide-binding site protein 1).

NAL14_HUMAN
NC score	0.525908 (rank : 13)	θ value	2.21117e-06 (rank : 17)
Query Neighborhood Hits	58	Target Neighborhood Hits	76	Shared Neighborhood Hits	31
SwissProt Accessions	Q86W24, Q7RTR6	Gene names	NALP14, NOD5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 14 (Nucleotide-binding oligomerization domain protein 5).

NALP5_HUMAN
NC score	0.520988 (rank : 14)	θ value	0.000158464 (rank : 23)
Query Neighborhood Hits	58	Target Neighborhood Hits	88	Shared Neighborhood Hits	30
SwissProt Accessions	P59047, Q86W29	Gene names	NALP5, MATER
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Mater protein homolog).

CIAS1_MOUSE
NC score	0.519022 (rank : 15)	θ value	1.53129e-07 (rank : 14)
Query Neighborhood Hits	58	Target Neighborhood Hits	67	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R4B8, Q6JEL0	Gene names	Cias1, Mmig1, Nalp3, Pypaf1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein homolog (PYRIN-containing APAF1-like protein 1) (Mast cell maturation-associated-inducible protein 1) (Cryopyrin).

NAL12_HUMAN
NC score	0.517239 (rank : 16)	θ value	2.88788e-06 (rank : 19)
Query Neighborhood Hits	58	Target Neighborhood Hits	96	Shared Neighborhood Hits	31
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

CIAS1_HUMAN
NC score	0.512051 (rank : 17)	θ value	2.88788e-06 (rank : 18)
Query Neighborhood Hits	58	Target Neighborhood Hits	76	Shared Neighborhood Hits	30
SwissProt Accessions	Q96P20, O75434, Q59H68, Q5JQS8, Q5JQS9, Q6TG35, Q8TCW0, Q8TEU9, Q8WXH9	Gene names	CIAS1, NALP3, PYPAF1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein (Cryopyrin) (NACHT-, LRR- and PYD-containing protein 3) (PYRIN-containing APAF1-like protein 1) (Angiotensin/vasopressin receptor AII/AVP-like).

NALP7_HUMAN
NC score	0.505973 (rank : 18)	θ value	2.44474e-05 (rank : 21)
Query Neighborhood Hits	58	Target Neighborhood Hits	65	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WX94, Q7RTR1	Gene names	NALP7, NOD12, PYPAF3
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 7 (PYRIN-containing APAF1-like protein 3).

NAL11_HUMAN
NC score	0.494649 (rank : 19)	θ value	0.00298849 (rank : 25)
Query Neighborhood Hits	58	Target Neighborhood Hits	66	Shared Neighborhood Hits	33
SwissProt Accessions	P59045, Q53ZZ0, Q8NBF5	Gene names	NALP11, NOD17, PYPAF6
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 11 (PYRIN-containing APAF1-like protein 6) (Nucleotide-binding oligomerization domain protein 17).

NALP5_MOUSE
NC score	0.493484 (rank : 20)	θ value	5.81887e-07 (rank : 15)
Query Neighborhood Hits	58	Target Neighborhood Hits	560	Shared Neighborhood Hits	30
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

NALP1_HUMAN
NC score	0.471373 (rank : 21)	θ value	7.1131e-05 (rank : 22)
Query Neighborhood Hits	58	Target Neighborhood Hits	138	Shared Neighborhood Hits	32
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

RGP1_HUMAN
NC score	0.463473 (rank : 22)	θ value	9.92553e-07 (rank : 16)
Query Neighborhood Hits	58	Target Neighborhood Hits	124	Shared Neighborhood Hits	26
SwissProt Accessions	P46060	Gene names	RANGAP1
Domain Architecture
Description	Ran GTPase-activating protein 1.

RGP1_MOUSE
NC score	0.439387 (rank : 23)	θ value	2.88788e-06 (rank : 20)
Query Neighborhood Hits	58	Target Neighborhood Hits	105	Shared Neighborhood Hits	26
SwissProt Accessions	P46061, Q60801	Gene names	Rangap1, Fug1
Domain Architecture
Description	Ran GTPase-activating protein 1.

LRC31_HUMAN
NC score	0.428875 (rank : 24)	θ value	0.00175202 (rank : 24)
Query Neighborhood Hits	58	Target Neighborhood Hits	139	Shared Neighborhood Hits	33
SwissProt Accessions	Q6UY01, Q8N848, Q9H5N5	Gene names	LRRC31
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 31.

C2TA_MOUSE
NC score	0.406229 (rank : 25)	θ value	0.0193708 (rank : 27)
Query Neighborhood Hits	58	Target Neighborhood Hits	131	Shared Neighborhood Hits	35
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).

NALP6_MOUSE
NC score	0.399470 (rank : 26)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	58	Target Neighborhood Hits	55	Shared Neighborhood Hits	25
SwissProt Accessions	Q91WS2, Q8K0L4	Gene names	Nalp6, Pypaf5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5-like).

NALP6_HUMAN
NC score	0.390319 (rank : 27)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	58	Target Neighborhood Hits	52	Shared Neighborhood Hits	24
SwissProt Accessions	P59044	Gene names	NALP6, PYPAF5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5).

C2TA_HUMAN
NC score	0.385711 (rank : 28)	θ value	0.0736092 (rank : 28)
Query Neighborhood Hits	58	Target Neighborhood Hits	190	Shared Neighborhood Hits	31
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

NAL10_HUMAN
NC score	0.350133 (rank : 29)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	58	Target Neighborhood Hits	55	Shared Neighborhood Hits	19
SwissProt Accessions	Q86W26, Q6JGT0	Gene names	NALP10, NOD8, PYNOD
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10 (Nucleotide-binding oligomerization domain protein 8).

NAL10_MOUSE
NC score	0.345167 (rank : 30)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	58	Target Neighborhood Hits	46	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CCN1	Gene names	Nalp10, Pynod
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10.

LRC45_MOUSE
NC score	0.271622 (rank : 31)	θ value	1.33837e-11 (rank : 5)
Query Neighborhood Hits	58	Target Neighborhood Hits	959	Shared Neighborhood Hits	36
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRC45_HUMAN
NC score	0.255124 (rank : 32)	θ value	4.30538e-10 (rank : 7)
Query Neighborhood Hits	58	Target Neighborhood Hits	933	Shared Neighborhood Hits	33
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

CAR12_HUMAN
NC score	0.165518 (rank : 33)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	58	Target Neighborhood Hits	132	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NPP4, Q96J81, Q96J82, Q96J83	Gene names	CARD12, CLAN, CLAN1
Domain Architecture
Description	Caspase recruitment domain-containing protein 12 (Ice protease- activating factor) (Ipaf) (CARD, LRR, and NACHT-containing protein) (Clan protein).

LMD1_HUMAN
NC score	0.159364 (rank : 34)	θ value	0.163984 (rank : 30)
Query Neighborhood Hits	58	Target Neighborhood Hits	169	Shared Neighborhood Hits	14
SwissProt Accessions	P29536	Gene names	LMOD1
Domain Architecture
Description	Leiomodin-1 (Leiomodin, muscle form) (64 kDa autoantigen D1) (64 kDa autoantigen 1D) (64 kDa autoantigen 1D3) (Thyroid-associated ophthalmopathy autoantigen) (Smooth muscle leiomodin) (SM-Lmod).

TMOD4_HUMAN
NC score	0.156866 (rank : 35)	θ value	0.125558 (rank : 29)
Query Neighborhood Hits	58	Target Neighborhood Hits	37	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZQ9, Q8WVL3, Q9UKH2	Gene names	TMOD4
Domain Architecture
Description	Tropomodulin-4 (Skeletal muscle tropomodulin) (Sk-Tmod).

TMOD4_MOUSE
NC score	0.147008 (rank : 36)	θ value	0.279714 (rank : 32)
Query Neighborhood Hits	58	Target Neighborhood Hits	36	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JLH8	Gene names	Tmod4
Domain Architecture
Description	Tropomodulin-4 (Skeletal muscle tropomodulin) (Sk-Tmod).

LRC41_MOUSE
NC score	0.145580 (rank : 37)	θ value	0.21417 (rank : 31)
Query Neighborhood Hits	58	Target Neighborhood Hits	37	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K1C9, Q91VX4	Gene names	Lrrc41, Muf1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 41 (Protein Muf1).

LRC41_HUMAN
NC score	0.136348 (rank : 38)	θ value	0.47712 (rank : 34)
Query Neighborhood Hits	58	Target Neighborhood Hits	51	Shared Neighborhood Hits	16
SwissProt Accessions	Q15345, Q71RA8, Q9BSM0	Gene names	LRRC41, MUF1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 41 (Protein Muf1).

TMOD1_HUMAN
NC score	0.133341 (rank : 39)	θ value	0.47712 (rank : 35)
Query Neighborhood Hits	58	Target Neighborhood Hits	32	Shared Neighborhood Hits	18
SwissProt Accessions	P28289, Q9BUF1	Gene names	TMOD1, TMOD
Domain Architecture
Description	Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod).

TMOD1_MOUSE
NC score	0.128653 (rank : 40)	θ value	2.36792 (rank : 47)
Query Neighborhood Hits	58	Target Neighborhood Hits	28	Shared Neighborhood Hits	17
SwissProt Accessions	P49813, Q9ERR9	Gene names	Tmod1, Tmod
Domain Architecture
Description	Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod).

TMOD2_HUMAN
NC score	0.120666 (rank : 41)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	58	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NZR1	Gene names	TMOD2, NTMOD
Domain Architecture
Description	Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod).

TMOD3_MOUSE
NC score	0.120079 (rank : 42)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	58	Target Neighborhood Hits	34	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JHJ0, Q3TIT1	Gene names	Tmod3
Domain Architecture
Description	Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod).

TMOD2_MOUSE
NC score	0.115812 (rank : 43)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	58	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JKK7, Q9JLH9	Gene names	Tmod2
Domain Architecture
Description	Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod).

TMOD3_HUMAN
NC score	0.109165 (rank : 44)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	58	Target Neighborhood Hits	35	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NYL9, Q9NT43, Q9NZR0	Gene names	TMOD3
Domain Architecture
Description	Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod).

LRC14_HUMAN
NC score	0.081140 (rank : 45)	θ value	0.813845 (rank : 38)
Query Neighborhood Hits	58	Target Neighborhood Hits	57	Shared Neighborhood Hits	16
SwissProt Accessions	Q15048	Gene names	LRRC14, KIAA0014
Domain Architecture
Description	Leucine-rich repeat-containing protein 14.

ASC_MOUSE
NC score	0.076864 (rank : 46)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	58	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q9EPB4, Q9D2W9	Gene names	Pycard, Asc
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein).

BIRC1_HUMAN
NC score	0.076063 (rank : 47)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	58	Target Neighborhood Hits	61	Shared Neighborhood Hits	19
SwissProt Accessions	Q13075, O75857, Q13730, Q99796	Gene names	BIRC1, NAIP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein).

BIR1F_MOUSE
NC score	0.064932 (rank : 48)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	58	Target Neighborhood Hits	88	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JIB6, O09121, O09122, P81704	Gene names	Birc1f, Naip-rs4, Naip6
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).

BIR1A_MOUSE
NC score	0.064578 (rank : 49)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	58	Target Neighborhood Hits	94	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QWK5, Q9JIB5, Q9R017	Gene names	Birc1a, Naip, Naip1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1).

BIR1E_MOUSE
NC score	0.062328 (rank : 50)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	58	Target Neighborhood Hits	93	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R016, O09121, O09122, P81703, Q9R029	Gene names	Birc1e, Naip-rs3, Naip5
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).

ASC_HUMAN
NC score	0.062271 (rank : 51)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	58	Target Neighborhood Hits	18	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ULZ3, Q96D12, Q9BSZ5, Q9HBD0, Q9NXJ8	Gene names	PYCARD, ASC, CARD5, TMS1
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (hASC) (PYD and CARD domain-containing protein) (Target of methylation-induced silencing 1) (Caspase recruitment domain-containing protein 5).

BIR1B_MOUSE
NC score	0.062178 (rank : 52)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	58	Target Neighborhood Hits	93	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QUK4, O09124, Q9R030	Gene names	Birc1b, Naip-rs6, Naip2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2).

BIR1G_MOUSE
NC score	0.061790 (rank : 53)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	58	Target Neighborhood Hits	92	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JIB3	Gene names	Birc1g, Naip7
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).

TLR4_HUMAN
NC score	0.037168 (rank : 54)	θ value	0.365318 (rank : 33)
Query Neighborhood Hits	58	Target Neighborhood Hits	298	Shared Neighborhood Hits	16
SwissProt Accessions	O00206, Q9UK78, Q9UM57	Gene names	TLR4
Domain Architecture
Description	Toll-like receptor 4 precursor (hToll) (CD284 antigen).

LRC33_MOUSE
NC score	0.036082 (rank : 55)	θ value	1.38821 (rank : 41)
Query Neighborhood Hits	58	Target Neighborhood Hits	296	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BMT4, Q3TIA8, Q8BTT4, Q8BUI7, Q8BY16, Q8R063	Gene names	Lrrc33
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 33 precursor.

ATP9A_HUMAN
NC score	0.034202 (rank : 56)	θ value	1.06291 (rank : 39)
Query Neighborhood Hits	58	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	O75110, Q5TFW5, Q5TFW6, Q5TFW9, Q6ZMF3, Q9NQK6, Q9NQK7	Gene names	ATP9A, ATPIIA, KIAA0611
Domain Architecture	No domain graphic available
Description	Probable phospholipid-transporting ATPase IIA (EC 3.6.3.1) (ATPase class II type 9A) (ATPase IIA).

ATP9A_MOUSE
NC score	0.034094 (rank : 57)	θ value	1.38821 (rank : 40)
Query Neighborhood Hits	58	Target Neighborhood Hits	61	Shared Neighborhood Hits	5
SwissProt Accessions	O70228, Q8VDI5, Q922L9	Gene names	Atp9a
Domain Architecture	No domain graphic available
Description	Probable phospholipid-transporting ATPase IIA (EC 3.6.3.1) (ATPase class II type 9A).

ATP9B_HUMAN
NC score	0.032629 (rank : 58)	θ value	0.813845 (rank : 37)
Query Neighborhood Hits	58	Target Neighborhood Hits	71	Shared Neighborhood Hits	5
SwissProt Accessions	O43861, O60872	Gene names	ATP9B, ATPIIB, NEO1L
Domain Architecture	No domain graphic available
Description	Probable phospholipid-transporting ATPase IIB (EC 3.6.3.1).

PP1R7_MOUSE
NC score	0.027387 (rank : 59)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	58	Target Neighborhood Hits	256	Shared Neighborhood Hits	15
SwissProt Accessions	Q3UM45, Q9CV31, Q9Z105	Gene names	Ppp1r7, Sds22
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22).

PIDD_MOUSE
NC score	0.025592 (rank : 60)	θ value	3.0926 (rank : 49)
Query Neighborhood Hits	58	Target Neighborhood Hits	256	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ERV7	Gene names	Lrdd, Pidd
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and death domain-containing protein.

TLR8_HUMAN
NC score	0.025172 (rank : 61)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	58	Target Neighborhood Hits	298	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NR97, Q6UXL6, Q9NYG9	Gene names	TLR8
Domain Architecture
Description	Toll-like receptor 8 precursor.

LGR5_HUMAN
NC score	0.023795 (rank : 62)	θ value	0.62314 (rank : 36)
Query Neighborhood Hits	58	Target Neighborhood Hits	452	Shared Neighborhood Hits	20
SwissProt Accessions	O75473, Q9UP75	Gene names	LGR5, GPR49, GPR67
Domain Architecture
Description	Leucine-rich repeat-containing G-protein coupled receptor 5 precursor (Orphan G-protein coupled receptor HG38) (G-protein coupled receptor 49) (G-protein coupled receptor 67).

LRC8C_HUMAN
NC score	0.023785 (rank : 63)	θ value	2.36792 (rank : 45)
Query Neighborhood Hits	58	Target Neighborhood Hits	255	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TDW0, Q9H075	Gene names	LRRC8C, AD158
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8C (Protein AD158).

DICER_HUMAN
NC score	0.023630 (rank : 64)	θ value	3.0926 (rank : 48)
Query Neighborhood Hits	58	Target Neighborhood Hits	126	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

IP3KA_HUMAN
NC score	0.022788 (rank : 65)	θ value	1.81305 (rank : 43)
Query Neighborhood Hits	58	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	P23677, Q8TAN3	Gene names	ITPKA
Domain Architecture
Description	Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase A) (IP3K A) (IP3 3-kinase A).

LRC8C_MOUSE
NC score	0.022094 (rank : 66)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	58	Target Neighborhood Hits	242	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R502, Q3TEP9, Q8C296, Q8R0N7, Q8R3G5	Gene names	Lrrc8c, Ad158
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8C (Protein AD158).

PDE5A_MOUSE
NC score	0.021216 (rank : 67)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	58	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CG03	Gene names	Pde5a, Pde5
Domain Architecture
Description	cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (CGB-PDE) (cGMP-binding cGMP-specific phosphodiesterase).

PDE5A_HUMAN
NC score	0.020772 (rank : 68)	θ value	1.81305 (rank : 44)
Query Neighborhood Hits	58	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	O76074, O75026, O75887, Q86UI0, Q86V66, Q9Y6Z6	Gene names	PDE5A, PDE5
Domain Architecture
Description	cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (CGB-PDE) (cGMP-binding cGMP-specific phosphodiesterase).

FMOD_MOUSE
NC score	0.015412 (rank : 69)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	58	Target Neighborhood Hits	286	Shared Neighborhood Hits	14
SwissProt Accessions	P50608	Gene names	Fmod
Domain Architecture
Description	Fibromodulin precursor (FM) (Collagen-binding 59 kDa protein) (Keratan sulfate proteoglycan fibromodulin) (KSPG fibromodulin).

FMOD_HUMAN
NC score	0.015015 (rank : 70)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	58	Target Neighborhood Hits	283	Shared Neighborhood Hits	13
SwissProt Accessions	Q06828, Q15331	Gene names	FMOD, FM
Domain Architecture
Description	Fibromodulin precursor (FM) (Collagen-binding 59 kDa protein) (Keratan sulfate proteoglycan fibromodulin) (KSPG fibromodulin).

OMGP_HUMAN
NC score	0.014339 (rank : 71)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	58	Target Neighborhood Hits	268	Shared Neighborhood Hits	12
SwissProt Accessions	P23515	Gene names	OMG, OMGP
Domain Architecture
Description	Oligodendrocyte-myelin glycoprotein precursor.

LR37A_HUMAN
NC score	0.010993 (rank : 72)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	58	Target Neighborhood Hits	720	Shared Neighborhood Hits	12
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

ANM3_HUMAN
NC score	0.007329 (rank : 73)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	58	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	O60678	Gene names	PRMT3, HRMT1L3
Domain Architecture
Description	Protein arginine N-methyltransferase 3 (EC 2.1.1.-) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3).