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Network neighborhood for query Sequence : C2TA_MOUSE

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C2TA_MOUSE
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

C2TA_HUMAN
θ value	0 (rank : 1)	NC score	0.952309 (rank : 2)
Query Neighborhood Hits	131	Target Neighborhood Hits	190	Shared Neighborhood Hits	53
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

C2TA_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	131	Target Neighborhood Hits	131	Shared Neighborhood Hits	131
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).

CAR15_MOUSE
θ value	6.84181e-24 (rank : 3)	NC score	0.706352 (rank : 3)
Query Neighborhood Hits	131	Target Neighborhood Hits	93	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K3Z0	Gene names	Card15, Nod2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2).

NALP6_HUMAN
θ value	1.5773e-20 (rank : 4)	NC score	0.664487 (rank : 6)
Query Neighborhood Hits	131	Target Neighborhood Hits	52	Shared Neighborhood Hits	32
SwissProt Accessions	P59044	Gene names	NALP6, PYPAF5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5).

NALP6_MOUSE
θ value	2.06002e-20 (rank : 5)	NC score	0.665727 (rank : 5)
Query Neighborhood Hits	131	Target Neighborhood Hits	55	Shared Neighborhood Hits	35
SwissProt Accessions	Q91WS2, Q8K0L4	Gene names	Nalp6, Pypaf5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5-like).

CARD4_HUMAN
θ value	3.88503e-19 (rank : 6)	NC score	0.653676 (rank : 9)
Query Neighborhood Hits	131	Target Neighborhood Hits	102	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y239, Q8IWF5	Gene names	CARD4, NOD1
Domain Architecture
Description	Caspase recruitment domain-containing protein 4 (Protein Nod1).

CARD4_MOUSE
θ value	3.28887e-18 (rank : 7)	NC score	0.661870 (rank : 7)
Query Neighborhood Hits	131	Target Neighborhood Hits	85	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BHB0, Q8BUT6	Gene names	Card4
Domain Architecture
Description	Caspase recruitment domain-containing protein 4.

NAL12_HUMAN
θ value	7.32683e-18 (rank : 8)	NC score	0.656124 (rank : 8)
Query Neighborhood Hits	131	Target Neighborhood Hits	96	Shared Neighborhood Hits	40
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

CAR15_HUMAN
θ value	1.058e-16 (rank : 9)	NC score	0.689298 (rank : 4)
Query Neighborhood Hits	131	Target Neighborhood Hits	77	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HC29, Q96RH5, Q96RH6, Q96RH8	Gene names	CARD15, IBD1, NOD2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2) (Inflammatory bowel disease protein 1).

CIAS1_HUMAN
θ value	8.95645e-16 (rank : 10)	NC score	0.645103 (rank : 10)
Query Neighborhood Hits	131	Target Neighborhood Hits	76	Shared Neighborhood Hits	38
SwissProt Accessions	Q96P20, O75434, Q59H68, Q5JQS8, Q5JQS9, Q6TG35, Q8TCW0, Q8TEU9, Q8WXH9	Gene names	CIAS1, NALP3, PYPAF1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein (Cryopyrin) (NACHT-, LRR- and PYD-containing protein 3) (PYRIN-containing APAF1-like protein 1) (Angiotensin/vasopressin receptor AII/AVP-like).

CIAS1_MOUSE
θ value	1.16975e-15 (rank : 11)	NC score	0.642680 (rank : 14)
Query Neighborhood Hits	131	Target Neighborhood Hits	67	Shared Neighborhood Hits	39
SwissProt Accessions	Q8R4B8, Q6JEL0	Gene names	Cias1, Mmig1, Nalp3, Pypaf1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein homolog (PYRIN-containing APAF1-like protein 1) (Mast cell maturation-associated-inducible protein 1) (Cryopyrin).

NALP7_HUMAN
θ value	3.76295e-14 (rank : 12)	NC score	0.644568 (rank : 12)
Query Neighborhood Hits	131	Target Neighborhood Hits	65	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WX94, Q7RTR1	Gene names	NALP7, NOD12, PYPAF3
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 7 (PYRIN-containing APAF1-like protein 3).

NAL10_HUMAN
θ value	8.38298e-14 (rank : 13)	NC score	0.645095 (rank : 11)
Query Neighborhood Hits	131	Target Neighborhood Hits	55	Shared Neighborhood Hits	29
SwissProt Accessions	Q86W26, Q6JGT0	Gene names	NALP10, NOD8, PYNOD
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10 (Nucleotide-binding oligomerization domain protein 8).

NALP2_HUMAN
θ value	8.38298e-14 (rank : 14)	NC score	0.644298 (rank : 13)
Query Neighborhood Hits	131	Target Neighborhood Hits	65	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NX02, Q53FL5, Q59G09, Q8IXT0, Q9BVN5, Q9H6G6, Q9HAV9, Q9NWK3	Gene names	NALP2, NBS1, PAN1, PYPAF2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 2 (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2) (Nucleotide-binding site protein 1).

NAL10_MOUSE
θ value	6.00763e-12 (rank : 15)	NC score	0.629107 (rank : 15)
Query Neighborhood Hits	131	Target Neighborhood Hits	46	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CCN1	Gene names	Nalp10, Pynod
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10.

NAL14_HUMAN
θ value	2.98157e-11 (rank : 16)	NC score	0.614188 (rank : 17)
Query Neighborhood Hits	131	Target Neighborhood Hits	76	Shared Neighborhood Hits	38
SwissProt Accessions	Q86W24, Q7RTR6	Gene names	NALP14, NOD5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 14 (Nucleotide-binding oligomerization domain protein 5).

NALP1_HUMAN
θ value	1.47974e-10 (rank : 17)	NC score	0.605764 (rank : 19)
Query Neighborhood Hits	131	Target Neighborhood Hits	138	Shared Neighborhood Hits	46
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

NAL13_HUMAN
θ value	4.30538e-10 (rank : 18)	NC score	0.613112 (rank : 18)
Query Neighborhood Hits	131	Target Neighborhood Hits	93	Shared Neighborhood Hits	40
SwissProt Accessions	Q86W25, Q7RTR5	Gene names	NALP13, NOD14
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 13 (Nucleotide-binding oligomerization domain protein 14).

NALP5_MOUSE
θ value	1.63604e-09 (rank : 19)	NC score	0.565985 (rank : 22)
Query Neighborhood Hits	131	Target Neighborhood Hits	560	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

NALP4_HUMAN
θ value	6.21693e-09 (rank : 20)	NC score	0.615286 (rank : 16)
Query Neighborhood Hits	131	Target Neighborhood Hits	81	Shared Neighborhood Hits	42
SwissProt Accessions	Q96MN2, Q86W87, Q96AY6	Gene names	NALP4, PAN2, PYPAF4, RNH2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 4 (PYRIN-containing APAF1-like protein 4) (PAAD and NACHT-containing protein 2) (PYRIN and NACHT- containing protein 2) (Ribonuclease inhibitor 2).

NAL11_HUMAN
θ value	5.81887e-07 (rank : 21)	NC score	0.567438 (rank : 21)
Query Neighborhood Hits	131	Target Neighborhood Hits	66	Shared Neighborhood Hits	34
SwissProt Accessions	P59045, Q53ZZ0, Q8NBF5	Gene names	NALP11, NOD17, PYPAF6
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 11 (PYRIN-containing APAF1-like protein 6) (Nucleotide-binding oligomerization domain protein 17).

LRC45_MOUSE
θ value	3.19293e-05 (rank : 22)	NC score	0.173619 (rank : 33)
Query Neighborhood Hits	131	Target Neighborhood Hits	959	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

RINI_HUMAN
θ value	0.00020696 (rank : 23)	NC score	0.534582 (rank : 23)
Query Neighborhood Hits	131	Target Neighborhood Hits	78	Shared Neighborhood Hits	45
SwissProt Accessions	P13489	Gene names	RNH1, PRI, RNH
Domain Architecture
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1) (RAI) (Placental ribonuclease inhibitor) (RNase inhibitor) (RI).

NALP5_HUMAN
θ value	0.000461057 (rank : 24)	NC score	0.586439 (rank : 20)
Query Neighborhood Hits	131	Target Neighborhood Hits	88	Shared Neighborhood Hits	39
SwissProt Accessions	P59047, Q86W29	Gene names	NALP5, MATER
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Mater protein homolog).

LRC20_MOUSE
θ value	0.00102713 (rank : 25)	NC score	0.132405 (rank : 42)
Query Neighborhood Hits	131	Target Neighborhood Hits	220	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CI70	Gene names	Lrrc20
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 20.

LRC34_HUMAN
θ value	0.00102713 (rank : 26)	NC score	0.444551 (rank : 25)
Query Neighborhood Hits	131	Target Neighborhood Hits	67	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IZ02	Gene names	LRRC34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

RGP1_HUMAN
θ value	0.00134147 (rank : 27)	NC score	0.318099 (rank : 28)
Query Neighborhood Hits	131	Target Neighborhood Hits	124	Shared Neighborhood Hits	25
SwissProt Accessions	P46060	Gene names	RANGAP1
Domain Architecture
Description	Ran GTPase-activating protein 1.

LRC20_HUMAN
θ value	0.00175202 (rank : 28)	NC score	0.122328 (rank : 43)
Query Neighborhood Hits	131	Target Neighborhood Hits	226	Shared Neighborhood Hits	35
SwissProt Accessions	Q8TCA0, Q5T6D4, Q5T6D6, Q9NVA6, Q9NVG3	Gene names	LRRC20
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 20.

RGP1_MOUSE
θ value	0.00665767 (rank : 29)	NC score	0.294799 (rank : 29)
Query Neighborhood Hits	131	Target Neighborhood Hits	105	Shared Neighborhood Hits	26
SwissProt Accessions	P46061, Q60801	Gene names	Rangap1, Fug1
Domain Architecture
Description	Ran GTPase-activating protein 1.

LRC34_MOUSE
θ value	0.0193708 (rank : 30)	NC score	0.406229 (rank : 26)
Query Neighborhood Hits	131	Target Neighborhood Hits	58	Shared Neighborhood Hits	35
SwissProt Accessions	Q9DAM1	Gene names	Lrrc34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

LRC45_HUMAN
θ value	0.0193708 (rank : 31)	NC score	0.151097 (rank : 40)
Query Neighborhood Hits	131	Target Neighborhood Hits	933	Shared Neighborhood Hits	42
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

BIRC1_HUMAN
θ value	0.0252991 (rank : 32)	NC score	0.183230 (rank : 32)
Query Neighborhood Hits	131	Target Neighborhood Hits	61	Shared Neighborhood Hits	30
SwissProt Accessions	Q13075, O75857, Q13730, Q99796	Gene names	BIRC1, NAIP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein).

RINI_MOUSE
θ value	0.0252991 (rank : 33)	NC score	0.518067 (rank : 24)
Query Neighborhood Hits	131	Target Neighborhood Hits	87	Shared Neighborhood Hits	39
SwissProt Accessions	Q91VI7, Q924P4	Gene names	Rnh1, Rnh
Domain Architecture	No domain graphic available
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1).

LRC31_HUMAN
θ value	0.0431538 (rank : 34)	NC score	0.334682 (rank : 27)
Query Neighborhood Hits	131	Target Neighborhood Hits	139	Shared Neighborhood Hits	42
SwissProt Accessions	Q6UY01, Q8N848, Q9H5N5	Gene names	LRRC31
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 31.

BIR1B_MOUSE
θ value	0.0961366 (rank : 35)	NC score	0.157727 (rank : 38)
Query Neighborhood Hits	131	Target Neighborhood Hits	93	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QUK4, O09124, Q9R030	Gene names	Birc1b, Naip-rs6, Naip2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2).

FA62A_MOUSE
θ value	0.125558 (rank : 36)	NC score	0.038271 (rank : 87)
Query Neighborhood Hits	131	Target Neighborhood Hits	155	Shared Neighborhood Hits	4
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

SLIT1_HUMAN
θ value	0.125558 (rank : 37)	NC score	0.039817 (rank : 80)
Query Neighborhood Hits	131	Target Neighborhood Hits	700	Shared Neighborhood Hits	35
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

SLIT1_MOUSE
θ value	0.125558 (rank : 38)	NC score	0.039170 (rank : 83)
Query Neighborhood Hits	131	Target Neighborhood Hits	715	Shared Neighborhood Hits	34
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

VACHT_MOUSE
θ value	0.163984 (rank : 39)	NC score	0.034359 (rank : 88)
Query Neighborhood Hits	131	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	O35304	Gene names	Slc18a3, Vacht
Domain Architecture
Description	Vesicular acetylcholine transporter (VAChT) (Solute carrier family 18 member 3).

KERA_MOUSE
θ value	0.21417 (rank : 40)	NC score	0.048212 (rank : 67)
Query Neighborhood Hits	131	Target Neighborhood Hits	264	Shared Neighborhood Hits	28
SwissProt Accessions	O35367	Gene names	Kera, Ktcn
Domain Architecture
Description	Keratocan precursor (KTN) (Keratan sulfate proteoglycan keratocan).

LRSM1_MOUSE
θ value	0.279714 (rank : 41)	NC score	0.041644 (rank : 75)
Query Neighborhood Hits	131	Target Neighborhood Hits	874	Shared Neighborhood Hits	35
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

TLR9_MOUSE
θ value	0.279714 (rank : 42)	NC score	0.053868 (rank : 59)
Query Neighborhood Hits	131	Target Neighborhood Hits	291	Shared Neighborhood Hits	40
SwissProt Accessions	Q9EQU3, Q99MF2, Q99MQ8	Gene names	Tlr9
Domain Architecture
Description	Toll-like receptor 9 precursor (CD289 antigen).

TMOD1_HUMAN
θ value	0.279714 (rank : 43)	NC score	0.100179 (rank : 44)
Query Neighborhood Hits	131	Target Neighborhood Hits	32	Shared Neighborhood Hits	18
SwissProt Accessions	P28289, Q9BUF1	Gene names	TMOD1, TMOD
Domain Architecture
Description	Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod).

RU2A_HUMAN
θ value	0.365318 (rank : 44)	NC score	0.051464 (rank : 62)
Query Neighborhood Hits	131	Target Neighborhood Hits	130	Shared Neighborhood Hits	18
SwissProt Accessions	P09661, Q8TBD2	Gene names	SNRPA1
Domain Architecture	No domain graphic available
Description	U2 small nuclear ribonucleoprotein A' (U2 snRNP-A').

SMOO_HUMAN
θ value	0.365318 (rank : 45)	NC score	0.044855 (rank : 71)
Query Neighborhood Hits	131	Target Neighborhood Hits	391	Shared Neighborhood Hits	14
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

TAF3_HUMAN
θ value	0.365318 (rank : 46)	NC score	0.031277 (rank : 95)
Query Neighborhood Hits	131	Target Neighborhood Hits	568	Shared Neighborhood Hits	9
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

ASPN_HUMAN
θ value	0.47712 (rank : 47)	NC score	0.047454 (rank : 68)
Query Neighborhood Hits	131	Target Neighborhood Hits	274	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BXN1, Q96K79, Q96LD0, Q9NXP3	Gene names	ASPN, PLAP1
Domain Architecture
Description	Asporin precursor (Periodontal ligament-associated protein 1) (PLAP- 1).

BIR1A_MOUSE
θ value	0.47712 (rank : 48)	NC score	0.162709 (rank : 35)
Query Neighborhood Hits	131	Target Neighborhood Hits	94	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QWK5, Q9JIB5, Q9R017	Gene names	Birc1a, Naip, Naip1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1).

CAR12_HUMAN
θ value	0.47712 (rank : 49)	NC score	0.247252 (rank : 31)
Query Neighborhood Hits	131	Target Neighborhood Hits	132	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NPP4, Q96J81, Q96J82, Q96J83	Gene names	CARD12, CLAN, CLAN1
Domain Architecture
Description	Caspase recruitment domain-containing protein 12 (Ice protease- activating factor) (Ipaf) (CARD, LRR, and NACHT-containing protein) (Clan protein).

KERA_HUMAN
θ value	0.47712 (rank : 50)	NC score	0.048313 (rank : 66)
Query Neighborhood Hits	131	Target Neighborhood Hits	275	Shared Neighborhood Hits	30
SwissProt Accessions	O60938	Gene names	KERA
Domain Architecture
Description	Keratocan precursor (KTN) (Keratan sulfate proteoglycan keratocan).

RGS3_MOUSE
θ value	0.47712 (rank : 51)	NC score	0.012956 (rank : 120)
Query Neighborhood Hits	131	Target Neighborhood Hits	1621	Shared Neighborhood Hits	23
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SYNJ1_HUMAN
θ value	0.47712 (rank : 52)	NC score	0.031302 (rank : 94)
Query Neighborhood Hits	131	Target Neighborhood Hits	498	Shared Neighborhood Hits	11
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TLR1_HUMAN
θ value	0.47712 (rank : 53)	NC score	0.038921 (rank : 85)
Query Neighborhood Hits	131	Target Neighborhood Hits	280	Shared Neighborhood Hits	31
SwissProt Accessions	Q15399, O15452, Q9UG90	Gene names	TLR1, KIAA0012
Domain Architecture
Description	Toll-like receptor 1 precursor (Toll/interleukin-1 receptor-like protein) (TIL) (CD281 antigen).

TLR9_HUMAN
θ value	0.47712 (rank : 54)	NC score	0.049038 (rank : 65)
Query Neighborhood Hits	131	Target Neighborhood Hits	295	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NR96, Q6UVZ2, Q9HD68, Q9HD69, Q9HD70, Q9NYC2, Q9NYC3	Gene names	TLR9
Domain Architecture
Description	Toll-like receptor 9 precursor (CD289 antigen).

SLIT2_MOUSE
θ value	0.62314 (rank : 55)	NC score	0.041041 (rank : 78)
Query Neighborhood Hits	131	Target Neighborhood Hits	684	Shared Neighborhood Hits	36
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

BAZ2A_MOUSE
θ value	0.813845 (rank : 56)	NC score	0.019541 (rank : 108)
Query Neighborhood Hits	131	Target Neighborhood Hits	744	Shared Neighborhood Hits	15
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BIR1F_MOUSE
θ value	0.813845 (rank : 57)	NC score	0.161567 (rank : 36)
Query Neighborhood Hits	131	Target Neighborhood Hits	88	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JIB6, O09121, O09122, P81704	Gene names	Birc1f, Naip-rs4, Naip6
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).

CEP72_MOUSE
θ value	0.813845 (rank : 58)	NC score	0.046570 (rank : 70)
Query Neighborhood Hits	131	Target Neighborhood Hits	381	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D3R3, Q8BM53, Q9D0B7	Gene names	Cep72
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

K1543_HUMAN
θ value	0.813845 (rank : 59)	NC score	0.029931 (rank : 96)
Query Neighborhood Hits	131	Target Neighborhood Hits	435	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

PHLB1_HUMAN
θ value	0.813845 (rank : 60)	NC score	0.025519 (rank : 98)
Query Neighborhood Hits	131	Target Neighborhood Hits	1038	Shared Neighborhood Hits	14
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

BIR1G_MOUSE
θ value	1.06291 (rank : 61)	NC score	0.156397 (rank : 39)
Query Neighborhood Hits	131	Target Neighborhood Hits	92	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JIB3	Gene names	Birc1g, Naip7
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).

CEP72_HUMAN
θ value	1.06291 (rank : 62)	NC score	0.044097 (rank : 72)
Query Neighborhood Hits	131	Target Neighborhood Hits	374	Shared Neighborhood Hits	16
SwissProt Accessions	Q9P209, Q9BV03, Q9BWM3, Q9NVR4	Gene names	CEP72, KIAA1519
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

DGCR8_MOUSE
θ value	1.06291 (rank : 63)	NC score	0.041627 (rank : 76)
Query Neighborhood Hits	131	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EQM6	Gene names	Dgcr8
Domain Architecture	No domain graphic available
Description	DGCR8 protein (DiGeorge syndrome critical region 8 homolog) (Gy1).

LRC47_HUMAN
θ value	1.06291 (rank : 64)	NC score	0.052878 (rank : 60)
Query Neighborhood Hits	131	Target Neighborhood Hits	300	Shared Neighborhood Hits	37
SwissProt Accessions	Q8N1G4, Q9ULN5	Gene names	LRRC47, KIAA1185
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 47.

ATX1_MOUSE
θ value	1.38821 (rank : 65)	NC score	0.024310 (rank : 100)
Query Neighborhood Hits	131	Target Neighborhood Hits	264	Shared Neighborhood Hits	4
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

BIR1E_MOUSE
θ value	1.38821 (rank : 66)	NC score	0.158063 (rank : 37)
Query Neighborhood Hits	131	Target Neighborhood Hits	93	Shared Neighborhood Hits	32
SwissProt Accessions	Q9R016, O09121, O09122, P81703, Q9R029	Gene names	Birc1e, Naip-rs3, Naip5
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).

DGCR8_HUMAN
θ value	1.38821 (rank : 67)	NC score	0.041266 (rank : 77)
Query Neighborhood Hits	131	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WYQ5, Q6DCB2, Q6MZE9, Q6Y2L0, Q96G39, Q96GP8, Q9H6L8, Q9H6T7, Q9NRW2	Gene names	DGCR8, C22orf12, DGCRK6
Domain Architecture
Description	DGCR8 protein (DiGeorge syndrome critical region 8).

FA62A_HUMAN
θ value	1.38821 (rank : 68)	NC score	0.031758 (rank : 93)
Query Neighborhood Hits	131	Target Neighborhood Hits	168	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

LRC41_HUMAN
θ value	1.38821 (rank : 69)	NC score	0.057413 (rank : 58)
Query Neighborhood Hits	131	Target Neighborhood Hits	51	Shared Neighborhood Hits	16
SwissProt Accessions	Q15345, Q71RA8, Q9BSM0	Gene names	LRRC41, MUF1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 41 (Protein Muf1).

LRC57_HUMAN
θ value	1.38821 (rank : 70)	NC score	0.062920 (rank : 55)
Query Neighborhood Hits	131	Target Neighborhood Hits	271	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N9N7, Q7Z2Z6, Q8N1T6	Gene names	LRRC57
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 57.

LRC57_MOUSE
θ value	1.38821 (rank : 71)	NC score	0.058266 (rank : 57)
Query Neighborhood Hits	131	Target Neighborhood Hits	267	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D1G5, Q9DC95	Gene names	Lrrc57
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 57.

PS1C2_HUMAN
θ value	1.38821 (rank : 72)	NC score	0.061700 (rank : 56)
Query Neighborhood Hits	131	Target Neighborhood Hits	66	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UIG4	Gene names	PSORS1C2, C6orf17, SPR1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein precursor (SPR1 protein).

LRC47_MOUSE
θ value	1.81305 (rank : 73)	NC score	0.052652 (rank : 61)
Query Neighborhood Hits	131	Target Neighborhood Hits	299	Shared Neighborhood Hits	36
SwissProt Accessions	Q505F5, Q3U380, Q6ZPW2, Q9CUZ0	Gene names	Lrrc47, Kiaa1185
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 47.

SOS1_HUMAN
θ value	1.81305 (rank : 74)	NC score	0.022211 (rank : 104)
Query Neighborhood Hits	131	Target Neighborhood Hits	274	Shared Neighborhood Hits	5
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

TMOD1_MOUSE
θ value	1.81305 (rank : 75)	NC score	0.091047 (rank : 46)
Query Neighborhood Hits	131	Target Neighborhood Hits	28	Shared Neighborhood Hits	17
SwissProt Accessions	P49813, Q9ERR9	Gene names	Tmod1, Tmod
Domain Architecture
Description	Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod).

CABYR_HUMAN
θ value	2.36792 (rank : 76)	NC score	0.026000 (rank : 97)
Query Neighborhood Hits	131	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	O75952, Q8WXW5, Q9HAY3, Q9HAY4, Q9HAY5, Q9HCY9	Gene names	CABYR, CBP86, FSP2
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86) (Fibrousheathin-2) (FSP-2).

PGS1_MOUSE
θ value	2.36792 (rank : 77)	NC score	0.039386 (rank : 82)
Query Neighborhood Hits	131	Target Neighborhood Hits	265	Shared Neighborhood Hits	30
SwissProt Accessions	P28653, Q61355	Gene names	Bgn
Domain Architecture
Description	Biglycan precursor (Bone/cartilage proteoglycan I) (PG-S1).

RHG09_HUMAN
θ value	2.36792 (rank : 78)	NC score	0.011381 (rank : 124)
Query Neighborhood Hits	131	Target Neighborhood Hits	186	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

SLIT2_HUMAN
θ value	2.36792 (rank : 79)	NC score	0.034118 (rank : 89)
Query Neighborhood Hits	131	Target Neighborhood Hits	708	Shared Neighborhood Hits	34
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

CO039_HUMAN
θ value	3.0926 (rank : 80)	NC score	0.018812 (rank : 109)
Query Neighborhood Hits	131	Target Neighborhood Hits	264	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

FA8_HUMAN
θ value	3.0926 (rank : 81)	NC score	0.016582 (rank : 113)
Query Neighborhood Hits	131	Target Neighborhood Hits	112	Shared Neighborhood Hits	6
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

K0319_HUMAN
θ value	3.0926 (rank : 82)	NC score	0.020599 (rank : 105)
Query Neighborhood Hits	131	Target Neighborhood Hits	154	Shared Neighborhood Hits	9
SwissProt Accessions	Q5VV43, Q9UJC8, Q9Y4G7	Gene names	KIAA0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

LIPA3_HUMAN
θ value	3.0926 (rank : 83)	NC score	0.010214 (rank : 128)
Query Neighborhood Hits	131	Target Neighborhood Hits	828	Shared Neighborhood Hits	12
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

MIA2_MOUSE
θ value	3.0926 (rank : 84)	NC score	0.022950 (rank : 103)
Query Neighborhood Hits	131	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q91ZV0	Gene names	Mia2
Domain Architecture	No domain graphic available
Description	Melanoma inhibitory activity protein 2 precursor.

PEO1_MOUSE
θ value	3.0926 (rank : 85)	NC score	0.023512 (rank : 101)
Query Neighborhood Hits	131	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CIW5, Q8K1Z1	Gene names	Peo1
Domain Architecture	No domain graphic available
Description	Twinkle protein, mitochondrial precursor (EC 3.6.1.-) (T7 gp4-like protein with intramitochondrial nucleoid localization) (T7-like mitochondrial DNA helicase) (Progressive external ophthalmoplegia 1 protein homolog).

TMOD2_HUMAN
θ value	3.0926 (rank : 86)	NC score	0.094189 (rank : 45)
Query Neighborhood Hits	131	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NZR1	Gene names	TMOD2, NTMOD
Domain Architecture
Description	Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod).

TXND2_HUMAN
θ value	3.0926 (rank : 87)	NC score	0.013672 (rank : 116)
Query Neighborhood Hits	131	Target Neighborhood Hits	793	Shared Neighborhood Hits	13
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

ZFYV1_HUMAN
θ value	3.0926 (rank : 88)	NC score	0.020290 (rank : 106)
Query Neighborhood Hits	131	Target Neighborhood Hits	166	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

ASPN_MOUSE
θ value	4.03905 (rank : 89)	NC score	0.040971 (rank : 79)
Query Neighborhood Hits	131	Target Neighborhood Hits	277	Shared Neighborhood Hits	32
SwissProt Accessions	Q99MQ4, Q9D6A2	Gene names	Aspn
Domain Architecture
Description	Asporin precursor.

ECM2_HUMAN
θ value	4.03905 (rank : 90)	NC score	0.046804 (rank : 69)
Query Neighborhood Hits	131	Target Neighborhood Hits	402	Shared Neighborhood Hits	37
SwissProt Accessions	O94769	Gene names	ECM2
Domain Architecture
Description	Extracellular matrix protein 2 precursor (Matrix glycoprotein SC1/ECM2).

LRC56_MOUSE
θ value	4.03905 (rank : 91)	NC score	0.024641 (rank : 99)
Query Neighborhood Hits	131	Target Neighborhood Hits	100	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K375, Q571F2	Gene names	Lrrc56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

PHLB1_MOUSE
θ value	4.03905 (rank : 92)	NC score	0.022981 (rank : 102)
Query Neighborhood Hits	131	Target Neighborhood Hits	678	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

SPEG_HUMAN
θ value	4.03905 (rank : 93)	NC score	-0.001306 (rank : 139)
Query Neighborhood Hits	131	Target Neighborhood Hits	1762	Shared Neighborhood Hits	21
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

STAM1_HUMAN
θ value	4.03905 (rank : 94)	NC score	0.007270 (rank : 133)
Query Neighborhood Hits	131	Target Neighborhood Hits	271	Shared Neighborhood Hits	3
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

TMOD2_MOUSE
θ value	4.03905 (rank : 95)	NC score	0.086260 (rank : 47)
Query Neighborhood Hits	131	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JKK7, Q9JLH9	Gene names	Tmod2
Domain Architecture
Description	Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod).

ANR21_HUMAN
θ value	5.27518 (rank : 96)	NC score	0.006714 (rank : 135)
Query Neighborhood Hits	131	Target Neighborhood Hits	864	Shared Neighborhood Hits	13
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

K0226_HUMAN
θ value	5.27518 (rank : 97)	NC score	0.015789 (rank : 114)
Query Neighborhood Hits	131	Target Neighborhood Hits	92	Shared Neighborhood Hits	6
SwissProt Accessions	Q92622	Gene names	KIAA0226
Domain Architecture	No domain graphic available
Description	Protein KIAA0226.

LRC40_MOUSE
θ value	5.27518 (rank : 98)	NC score	0.042427 (rank : 74)
Query Neighborhood Hits	131	Target Neighborhood Hits	311	Shared Neighborhood Hits	41
SwissProt Accessions	Q9CRC8, Q78WQ9, Q8BS83	Gene names	Lrrc40
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 40.

LRC41_MOUSE
θ value	5.27518 (rank : 99)	NC score	0.050796 (rank : 64)
Query Neighborhood Hits	131	Target Neighborhood Hits	37	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K1C9, Q91VX4	Gene names	Lrrc41, Muf1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 41 (Protein Muf1).

POT15_HUMAN
θ value	5.27518 (rank : 100)	NC score	0.006847 (rank : 134)
Query Neighborhood Hits	131	Target Neighborhood Hits	893	Shared Neighborhood Hits	13
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

RU2A_MOUSE
θ value	5.27518 (rank : 101)	NC score	0.038934 (rank : 84)
Query Neighborhood Hits	131	Target Neighborhood Hits	131	Shared Neighborhood Hits	18
SwissProt Accessions	P57784, Q3U7R8, Q8K2W4, Q91YW1, Q9JKQ3	Gene names	Snrpa1
Domain Architecture	No domain graphic available
Description	U2 small nuclear ribonucleoprotein A' (U2 snRNP-A').

SLIT3_HUMAN
θ value	5.27518 (rank : 102)	NC score	0.033604 (rank : 91)
Query Neighborhood Hits	131	Target Neighborhood Hits	682	Shared Neighborhood Hits	34
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

SOS1_MOUSE
θ value	5.27518 (rank : 103)	NC score	0.018741 (rank : 110)
Query Neighborhood Hits	131	Target Neighborhood Hits	281	Shared Neighborhood Hits	6
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

SRRM2_HUMAN
θ value	5.27518 (rank : 104)	NC score	0.013371 (rank : 118)
Query Neighborhood Hits	131	Target Neighborhood Hits	1296	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

STK10_MOUSE
θ value	5.27518 (rank : 105)	NC score	-0.001471 (rank : 140)
Query Neighborhood Hits	131	Target Neighborhood Hits	2132	Shared Neighborhood Hits	18
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TMOD4_MOUSE
θ value	5.27518 (rank : 106)	NC score	0.082612 (rank : 49)
Query Neighborhood Hits	131	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JLH8	Gene names	Tmod4
Domain Architecture
Description	Tropomodulin-4 (Skeletal muscle tropomodulin) (Sk-Tmod).

TNR3_MOUSE
θ value	5.27518 (rank : 107)	NC score	0.009983 (rank : 129)
Query Neighborhood Hits	131	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

ZFYV1_MOUSE
θ value	5.27518 (rank : 108)	NC score	0.018458 (rank : 111)
Query Neighborhood Hits	131	Target Neighborhood Hits	153	Shared Neighborhood Hits	3
SwissProt Accessions	Q810J8	Gene names	Zfyve1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1.

BBS4_HUMAN
θ value	6.88961 (rank : 109)	NC score	0.010270 (rank : 127)
Query Neighborhood Hits	131	Target Neighborhood Hits	109	Shared Neighborhood Hits	3
SwissProt Accessions	Q96RK4, Q8NHU9, Q96H45	Gene names	BBS4
Domain Architecture
Description	Bardet-Biedl syndrome 4 protein.

F51A1_HUMAN
θ value	6.88961 (rank : 110)	NC score	0.016932 (rank : 112)
Query Neighborhood Hits	131	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NWZ8	Gene names	FAM51A1
Domain Architecture	No domain graphic available
Description	Protein FAM51A1.

GPNMB_HUMAN
θ value	6.88961 (rank : 111)	NC score	0.013480 (rank : 117)
Query Neighborhood Hits	131	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q14956, Q6UVX1, Q8N1A1	Gene names	GPNMB, HGFIN, NMB
Domain Architecture
Description	Transmembrane glycoprotein NMB precursor (Transmembrane glycoprotein HGFIN).

HECD1_HUMAN
θ value	6.88961 (rank : 112)	NC score	0.004603 (rank : 137)
Query Neighborhood Hits	131	Target Neighborhood Hits	371	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

HGFA_HUMAN
θ value	6.88961 (rank : 113)	NC score	0.003996 (rank : 138)
Query Neighborhood Hits	131	Target Neighborhood Hits	436	Shared Neighborhood Hits	9
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

MCES_MOUSE
θ value	6.88961 (rank : 114)	NC score	0.013827 (rank : 115)
Query Neighborhood Hits	131	Target Neighborhood Hits	88	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D0L8, Q3V3U9, Q6ZQC6, Q9D5F1	Gene names	Rnmt, Kiaa0398
Domain Architecture	No domain graphic available
Description	mRNA cap guanine-N7 methyltransferase (EC 2.1.1.56) (mRNA (guanine- N(7)-)-methyltransferase) (RG7MT1) (mRNA cap methyltransferase).

OMD_HUMAN
θ value	6.88961 (rank : 115)	NC score	0.042862 (rank : 73)
Query Neighborhood Hits	131	Target Neighborhood Hits	275	Shared Neighborhood Hits	30
SwissProt Accessions	Q99983	Gene names	OMD
Domain Architecture
Description	Osteomodulin precursor (Osteoadherin) (OSAD) (Keratan sulfate proteoglycan osteomodulin) (KSPG osteomodulin).

PRELP_MOUSE
θ value	6.88961 (rank : 116)	NC score	0.039581 (rank : 81)
Query Neighborhood Hits	131	Target Neighborhood Hits	295	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JK53	Gene names	Prelp
Domain Architecture
Description	Prolargin precursor (Proline-arginine-rich end leucine-rich repeat protein).

ZC11A_HUMAN
θ value	6.88961 (rank : 117)	NC score	0.011330 (rank : 125)
Query Neighborhood Hits	131	Target Neighborhood Hits	170	Shared Neighborhood Hits	2
SwissProt Accessions	O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7	Gene names	ZC3H11A, KIAA0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

ALDR_HUMAN
θ value	8.99809 (rank : 118)	NC score	0.006236 (rank : 136)
Query Neighborhood Hits	131	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P15121, Q9BS21, Q9UCI9	Gene names	AKR1B1, ALDR1
Domain Architecture
Description	Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase).

ALDR_MOUSE
θ value	8.99809 (rank : 119)	NC score	0.012030 (rank : 122)
Query Neighborhood Hits	131	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	P45376, O70130, Q99KC9	Gene names	Akr1b1, Akr1b3, Aldor1, Aldr1
Domain Architecture
Description	Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase).

FBLN2_MOUSE
θ value	8.99809 (rank : 120)	NC score	0.007331 (rank : 132)
Query Neighborhood Hits	131	Target Neighborhood Hits	505	Shared Neighborhood Hits	18
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

GA2L1_MOUSE
θ value	8.99809 (rank : 121)	NC score	0.009886 (rank : 130)
Query Neighborhood Hits	131	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

HSF1_MOUSE
θ value	8.99809 (rank : 122)	NC score	0.008475 (rank : 131)
Query Neighborhood Hits	131	Target Neighborhood Hits	267	Shared Neighborhood Hits	7
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

MLL2_HUMAN
θ value	8.99809 (rank : 123)	NC score	0.012340 (rank : 121)
Query Neighborhood Hits	131	Target Neighborhood Hits	1788	Shared Neighborhood Hits	26
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

OS9_HUMAN
θ value	8.99809 (rank : 124)	NC score	0.013261 (rank : 119)
Query Neighborhood Hits	131	Target Neighborhood Hits	134	Shared Neighborhood Hits	5
SwissProt Accessions	Q13438, O00579	Gene names	OS9
Domain Architecture	No domain graphic available
Description	Protein OS-9 precursor (Amplified in osteosarcoma 9).

PRELP_HUMAN
θ value	8.99809 (rank : 125)	NC score	0.038574 (rank : 86)
Query Neighborhood Hits	131	Target Neighborhood Hits	295	Shared Neighborhood Hits	28
SwissProt Accessions	P51888	Gene names	PRELP
Domain Architecture
Description	Prolargin precursor (Proline-arginine-rich end leucine-rich repeat protein).

RPGR1_MOUSE
θ value	8.99809 (rank : 126)	NC score	0.011734 (rank : 123)
Query Neighborhood Hits	131	Target Neighborhood Hits	713	Shared Neighborhood Hits	11
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

RSU1_HUMAN
θ value	8.99809 (rank : 127)	NC score	0.033778 (rank : 90)
Query Neighborhood Hits	131	Target Neighborhood Hits	250	Shared Neighborhood Hits	31
SwissProt Accessions	Q15404	Gene names	RSU1, RSP1
Domain Architecture
Description	Ras suppressor protein 1 (Rsu-1) (RSP-1).

SLIT3_MOUSE
θ value	8.99809 (rank : 128)	NC score	0.032600 (rank : 92)
Query Neighborhood Hits	131	Target Neighborhood Hits	700	Shared Neighborhood Hits	34
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

TBCE_HUMAN
θ value	8.99809 (rank : 129)	NC score	0.019607 (rank : 107)
Query Neighborhood Hits	131	Target Neighborhood Hits	141	Shared Neighborhood Hits	18
SwissProt Accessions	Q15813	Gene names	TBCE
Domain Architecture	No domain graphic available
Description	Tubulin-specific chaperone E (Tubulin-folding cofactor E).

TMOD4_HUMAN
θ value	8.99809 (rank : 130)	NC score	0.082848 (rank : 48)
Query Neighborhood Hits	131	Target Neighborhood Hits	37	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NZQ9, Q8WVL3, Q9UKH2	Gene names	TMOD4
Domain Architecture
Description	Tropomodulin-4 (Skeletal muscle tropomodulin) (Sk-Tmod).

WFS1_HUMAN
θ value	8.99809 (rank : 131)	NC score	0.010480 (rank : 126)
Query Neighborhood Hits	131	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	O76024, Q8N6I3, Q9UNW6	Gene names	WFS1
Domain Architecture	No domain graphic available
Description	Wolframin.

ASC_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.134131 (rank : 41)
Query Neighborhood Hits	131	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ULZ3, Q96D12, Q9BSZ5, Q9HBD0, Q9NXJ8	Gene names	PYCARD, ASC, CARD5, TMS1
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (hASC) (PYD and CARD domain-containing protein) (Target of methylation-induced silencing 1) (Caspase recruitment domain-containing protein 5).

ASC_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.163116 (rank : 34)
Query Neighborhood Hits	131	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	Q9EPB4, Q9D2W9	Gene names	Pycard, Asc
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein).

CARD8_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.064189 (rank : 54)
Query Neighborhood Hits	131	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2G2, Q6PGP8, Q96P82	Gene names	CARD8, KIAA0955, NDPP1
Domain Architecture
Description	Caspase recruitment domain-containing protein 8 (Apoptotic protein NDPP1) (DACAR) (CARD-inhibitor of NF-kappa-B-activating ligand) (CARDINAL) (Tumor-up-regulated CARD-containing antagonist of CASP9) (TUCAN).

CF154_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.289458 (rank : 30)
Query Neighborhood Hits	131	Target Neighborhood Hits	36	Shared Neighborhood Hits	28
SwissProt Accessions	Q5JTD7	Gene names	C6orf154
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf154.

LMD1_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.076417 (rank : 53)
Query Neighborhood Hits	131	Target Neighborhood Hits	169	Shared Neighborhood Hits	18
SwissProt Accessions	P29536	Gene names	LMOD1
Domain Architecture
Description	Leiomodin-1 (Leiomodin, muscle form) (64 kDa autoantigen D1) (64 kDa autoantigen 1D) (64 kDa autoantigen 1D3) (Thyroid-associated ophthalmopathy autoantigen) (Smooth muscle leiomodin) (SM-Lmod).

LRC14_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.051408 (rank : 63)
Query Neighborhood Hits	131	Target Neighborhood Hits	57	Shared Neighborhood Hits	21
SwissProt Accessions	Q15048	Gene names	LRRC14, KIAA0014
Domain Architecture
Description	Leucine-rich repeat-containing protein 14.

MEFV_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.079689 (rank : 51)
Query Neighborhood Hits	131	Target Neighborhood Hits	236	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

TMOD3_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.078024 (rank : 52)
Query Neighborhood Hits	131	Target Neighborhood Hits	35	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NYL9, Q9NT43, Q9NZR0	Gene names	TMOD3
Domain Architecture
Description	Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod).

TMOD3_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.079753 (rank : 50)
Query Neighborhood Hits	131	Target Neighborhood Hits	34	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JHJ0, Q3TIT1	Gene names	Tmod3
Domain Architecture
Description	Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod).

Hits sorted by NC score

C2TA_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	131	Target Neighborhood Hits	131	Shared Neighborhood Hits	131
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).

C2TA_HUMAN
NC score	0.952309 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	131	Target Neighborhood Hits	190	Shared Neighborhood Hits	53
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

CAR15_MOUSE
NC score	0.706352 (rank : 3)	θ value	6.84181e-24 (rank : 3)
Query Neighborhood Hits	131	Target Neighborhood Hits	93	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K3Z0	Gene names	Card15, Nod2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2).

CAR15_HUMAN
NC score	0.689298 (rank : 4)	θ value	1.058e-16 (rank : 9)
Query Neighborhood Hits	131	Target Neighborhood Hits	77	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HC29, Q96RH5, Q96RH6, Q96RH8	Gene names	CARD15, IBD1, NOD2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2) (Inflammatory bowel disease protein 1).

NALP6_MOUSE
NC score	0.665727 (rank : 5)	θ value	2.06002e-20 (rank : 5)
Query Neighborhood Hits	131	Target Neighborhood Hits	55	Shared Neighborhood Hits	35
SwissProt Accessions	Q91WS2, Q8K0L4	Gene names	Nalp6, Pypaf5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5-like).

NALP6_HUMAN
NC score	0.664487 (rank : 6)	θ value	1.5773e-20 (rank : 4)
Query Neighborhood Hits	131	Target Neighborhood Hits	52	Shared Neighborhood Hits	32
SwissProt Accessions	P59044	Gene names	NALP6, PYPAF5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5).

CARD4_MOUSE
NC score	0.661870 (rank : 7)	θ value	3.28887e-18 (rank : 7)
Query Neighborhood Hits	131	Target Neighborhood Hits	85	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BHB0, Q8BUT6	Gene names	Card4
Domain Architecture
Description	Caspase recruitment domain-containing protein 4.

NAL12_HUMAN
NC score	0.656124 (rank : 8)	θ value	7.32683e-18 (rank : 8)
Query Neighborhood Hits	131	Target Neighborhood Hits	96	Shared Neighborhood Hits	40
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

CARD4_HUMAN
NC score	0.653676 (rank : 9)	θ value	3.88503e-19 (rank : 6)
Query Neighborhood Hits	131	Target Neighborhood Hits	102	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y239, Q8IWF5	Gene names	CARD4, NOD1
Domain Architecture
Description	Caspase recruitment domain-containing protein 4 (Protein Nod1).

CIAS1_HUMAN
NC score	0.645103 (rank : 10)	θ value	8.95645e-16 (rank : 10)
Query Neighborhood Hits	131	Target Neighborhood Hits	76	Shared Neighborhood Hits	38
SwissProt Accessions	Q96P20, O75434, Q59H68, Q5JQS8, Q5JQS9, Q6TG35, Q8TCW0, Q8TEU9, Q8WXH9	Gene names	CIAS1, NALP3, PYPAF1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein (Cryopyrin) (NACHT-, LRR- and PYD-containing protein 3) (PYRIN-containing APAF1-like protein 1) (Angiotensin/vasopressin receptor AII/AVP-like).

NAL10_HUMAN
NC score	0.645095 (rank : 11)	θ value	8.38298e-14 (rank : 13)
Query Neighborhood Hits	131	Target Neighborhood Hits	55	Shared Neighborhood Hits	29
SwissProt Accessions	Q86W26, Q6JGT0	Gene names	NALP10, NOD8, PYNOD
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10 (Nucleotide-binding oligomerization domain protein 8).

NALP7_HUMAN
NC score	0.644568 (rank : 12)	θ value	3.76295e-14 (rank : 12)
Query Neighborhood Hits	131	Target Neighborhood Hits	65	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WX94, Q7RTR1	Gene names	NALP7, NOD12, PYPAF3
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 7 (PYRIN-containing APAF1-like protein 3).

NALP2_HUMAN
NC score	0.644298 (rank : 13)	θ value	8.38298e-14 (rank : 14)
Query Neighborhood Hits	131	Target Neighborhood Hits	65	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NX02, Q53FL5, Q59G09, Q8IXT0, Q9BVN5, Q9H6G6, Q9HAV9, Q9NWK3	Gene names	NALP2, NBS1, PAN1, PYPAF2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 2 (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2) (Nucleotide-binding site protein 1).

CIAS1_MOUSE
NC score	0.642680 (rank : 14)	θ value	1.16975e-15 (rank : 11)
Query Neighborhood Hits	131	Target Neighborhood Hits	67	Shared Neighborhood Hits	39
SwissProt Accessions	Q8R4B8, Q6JEL0	Gene names	Cias1, Mmig1, Nalp3, Pypaf1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein homolog (PYRIN-containing APAF1-like protein 1) (Mast cell maturation-associated-inducible protein 1) (Cryopyrin).

NAL10_MOUSE
NC score	0.629107 (rank : 15)	θ value	6.00763e-12 (rank : 15)
Query Neighborhood Hits	131	Target Neighborhood Hits	46	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CCN1	Gene names	Nalp10, Pynod
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10.

NALP4_HUMAN
NC score	0.615286 (rank : 16)	θ value	6.21693e-09 (rank : 20)
Query Neighborhood Hits	131	Target Neighborhood Hits	81	Shared Neighborhood Hits	42
SwissProt Accessions	Q96MN2, Q86W87, Q96AY6	Gene names	NALP4, PAN2, PYPAF4, RNH2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 4 (PYRIN-containing APAF1-like protein 4) (PAAD and NACHT-containing protein 2) (PYRIN and NACHT- containing protein 2) (Ribonuclease inhibitor 2).

NAL14_HUMAN
NC score	0.614188 (rank : 17)	θ value	2.98157e-11 (rank : 16)
Query Neighborhood Hits	131	Target Neighborhood Hits	76	Shared Neighborhood Hits	38
SwissProt Accessions	Q86W24, Q7RTR6	Gene names	NALP14, NOD5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 14 (Nucleotide-binding oligomerization domain protein 5).

NAL13_HUMAN
NC score	0.613112 (rank : 18)	θ value	4.30538e-10 (rank : 18)
Query Neighborhood Hits	131	Target Neighborhood Hits	93	Shared Neighborhood Hits	40
SwissProt Accessions	Q86W25, Q7RTR5	Gene names	NALP13, NOD14
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 13 (Nucleotide-binding oligomerization domain protein 14).

NALP1_HUMAN
NC score	0.605764 (rank : 19)	θ value	1.47974e-10 (rank : 17)
Query Neighborhood Hits	131	Target Neighborhood Hits	138	Shared Neighborhood Hits	46
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

NALP5_HUMAN
NC score	0.586439 (rank : 20)	θ value	0.000461057 (rank : 24)
Query Neighborhood Hits	131	Target Neighborhood Hits	88	Shared Neighborhood Hits	39
SwissProt Accessions	P59047, Q86W29	Gene names	NALP5, MATER
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Mater protein homolog).

NAL11_HUMAN
NC score	0.567438 (rank : 21)	θ value	5.81887e-07 (rank : 21)
Query Neighborhood Hits	131	Target Neighborhood Hits	66	Shared Neighborhood Hits	34
SwissProt Accessions	P59045, Q53ZZ0, Q8NBF5	Gene names	NALP11, NOD17, PYPAF6
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 11 (PYRIN-containing APAF1-like protein 6) (Nucleotide-binding oligomerization domain protein 17).

NALP5_MOUSE
NC score	0.565985 (rank : 22)	θ value	1.63604e-09 (rank : 19)
Query Neighborhood Hits	131	Target Neighborhood Hits	560	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

RINI_HUMAN
NC score	0.534582 (rank : 23)	θ value	0.00020696 (rank : 23)
Query Neighborhood Hits	131	Target Neighborhood Hits	78	Shared Neighborhood Hits	45
SwissProt Accessions	P13489	Gene names	RNH1, PRI, RNH
Domain Architecture
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1) (RAI) (Placental ribonuclease inhibitor) (RNase inhibitor) (RI).

RINI_MOUSE
NC score	0.518067 (rank : 24)	θ value	0.0252991 (rank : 33)
Query Neighborhood Hits	131	Target Neighborhood Hits	87	Shared Neighborhood Hits	39
SwissProt Accessions	Q91VI7, Q924P4	Gene names	Rnh1, Rnh
Domain Architecture	No domain graphic available
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1).

LRC34_HUMAN
NC score	0.444551 (rank : 25)	θ value	0.00102713 (rank : 26)
Query Neighborhood Hits	131	Target Neighborhood Hits	67	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IZ02	Gene names	LRRC34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

LRC34_MOUSE
NC score	0.406229 (rank : 26)	θ value	0.0193708 (rank : 30)
Query Neighborhood Hits	131	Target Neighborhood Hits	58	Shared Neighborhood Hits	35
SwissProt Accessions	Q9DAM1	Gene names	Lrrc34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

LRC31_HUMAN
NC score	0.334682 (rank : 27)	θ value	0.0431538 (rank : 34)
Query Neighborhood Hits	131	Target Neighborhood Hits	139	Shared Neighborhood Hits	42
SwissProt Accessions	Q6UY01, Q8N848, Q9H5N5	Gene names	LRRC31
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 31.

RGP1_HUMAN
NC score	0.318099 (rank : 28)	θ value	0.00134147 (rank : 27)
Query Neighborhood Hits	131	Target Neighborhood Hits	124	Shared Neighborhood Hits	25
SwissProt Accessions	P46060	Gene names	RANGAP1
Domain Architecture
Description	Ran GTPase-activating protein 1.

RGP1_MOUSE
NC score	0.294799 (rank : 29)	θ value	0.00665767 (rank : 29)
Query Neighborhood Hits	131	Target Neighborhood Hits	105	Shared Neighborhood Hits	26
SwissProt Accessions	P46061, Q60801	Gene names	Rangap1, Fug1
Domain Architecture
Description	Ran GTPase-activating protein 1.

CF154_HUMAN
NC score	0.289458 (rank : 30)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	131	Target Neighborhood Hits	36	Shared Neighborhood Hits	28
SwissProt Accessions	Q5JTD7	Gene names	C6orf154
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf154.

CAR12_HUMAN
NC score	0.247252 (rank : 31)	θ value	0.47712 (rank : 49)
Query Neighborhood Hits	131	Target Neighborhood Hits	132	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NPP4, Q96J81, Q96J82, Q96J83	Gene names	CARD12, CLAN, CLAN1
Domain Architecture
Description	Caspase recruitment domain-containing protein 12 (Ice protease- activating factor) (Ipaf) (CARD, LRR, and NACHT-containing protein) (Clan protein).

BIRC1_HUMAN
NC score	0.183230 (rank : 32)	θ value	0.0252991 (rank : 32)
Query Neighborhood Hits	131	Target Neighborhood Hits	61	Shared Neighborhood Hits	30
SwissProt Accessions	Q13075, O75857, Q13730, Q99796	Gene names	BIRC1, NAIP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein).

LRC45_MOUSE
NC score	0.173619 (rank : 33)	θ value	3.19293e-05 (rank : 22)
Query Neighborhood Hits	131	Target Neighborhood Hits	959	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

ASC_MOUSE
NC score	0.163116 (rank : 34)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	131	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	Q9EPB4, Q9D2W9	Gene names	Pycard, Asc
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein).

BIR1A_MOUSE
NC score	0.162709 (rank : 35)	θ value	0.47712 (rank : 48)
Query Neighborhood Hits	131	Target Neighborhood Hits	94	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QWK5, Q9JIB5, Q9R017	Gene names	Birc1a, Naip, Naip1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1).

BIR1F_MOUSE
NC score	0.161567 (rank : 36)	θ value	0.813845 (rank : 57)
Query Neighborhood Hits	131	Target Neighborhood Hits	88	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JIB6, O09121, O09122, P81704	Gene names	Birc1f, Naip-rs4, Naip6
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).

BIR1E_MOUSE
NC score	0.158063 (rank : 37)	θ value	1.38821 (rank : 66)
Query Neighborhood Hits	131	Target Neighborhood Hits	93	Shared Neighborhood Hits	32
SwissProt Accessions	Q9R016, O09121, O09122, P81703, Q9R029	Gene names	Birc1e, Naip-rs3, Naip5
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).

BIR1B_MOUSE
NC score	0.157727 (rank : 38)	θ value	0.0961366 (rank : 35)
Query Neighborhood Hits	131	Target Neighborhood Hits	93	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QUK4, O09124, Q9R030	Gene names	Birc1b, Naip-rs6, Naip2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2).

BIR1G_MOUSE
NC score	0.156397 (rank : 39)	θ value	1.06291 (rank : 61)
Query Neighborhood Hits	131	Target Neighborhood Hits	92	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JIB3	Gene names	Birc1g, Naip7
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).

LRC45_HUMAN
NC score	0.151097 (rank : 40)	θ value	0.0193708 (rank : 31)
Query Neighborhood Hits	131	Target Neighborhood Hits	933	Shared Neighborhood Hits	42
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

ASC_HUMAN
NC score	0.134131 (rank : 41)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	131	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ULZ3, Q96D12, Q9BSZ5, Q9HBD0, Q9NXJ8	Gene names	PYCARD, ASC, CARD5, TMS1
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (hASC) (PYD and CARD domain-containing protein) (Target of methylation-induced silencing 1) (Caspase recruitment domain-containing protein 5).

LRC20_MOUSE
NC score	0.132405 (rank : 42)	θ value	0.00102713 (rank : 25)
Query Neighborhood Hits	131	Target Neighborhood Hits	220	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CI70	Gene names	Lrrc20
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 20.

LRC20_HUMAN
NC score	0.122328 (rank : 43)	θ value	0.00175202 (rank : 28)
Query Neighborhood Hits	131	Target Neighborhood Hits	226	Shared Neighborhood Hits	35
SwissProt Accessions	Q8TCA0, Q5T6D4, Q5T6D6, Q9NVA6, Q9NVG3	Gene names	LRRC20
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 20.

TMOD1_HUMAN
NC score	0.100179 (rank : 44)	θ value	0.279714 (rank : 43)
Query Neighborhood Hits	131	Target Neighborhood Hits	32	Shared Neighborhood Hits	18
SwissProt Accessions	P28289, Q9BUF1	Gene names	TMOD1, TMOD
Domain Architecture
Description	Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod).

TMOD2_HUMAN
NC score	0.094189 (rank : 45)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	131	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NZR1	Gene names	TMOD2, NTMOD
Domain Architecture
Description	Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod).

TMOD1_MOUSE
NC score	0.091047 (rank : 46)	θ value	1.81305 (rank : 75)
Query Neighborhood Hits	131	Target Neighborhood Hits	28	Shared Neighborhood Hits	17
SwissProt Accessions	P49813, Q9ERR9	Gene names	Tmod1, Tmod
Domain Architecture
Description	Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod).

TMOD2_MOUSE
NC score	0.086260 (rank : 47)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	131	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JKK7, Q9JLH9	Gene names	Tmod2
Domain Architecture
Description	Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod).

TMOD4_HUMAN
NC score	0.082848 (rank : 48)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	131	Target Neighborhood Hits	37	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NZQ9, Q8WVL3, Q9UKH2	Gene names	TMOD4
Domain Architecture
Description	Tropomodulin-4 (Skeletal muscle tropomodulin) (Sk-Tmod).

TMOD4_MOUSE
NC score	0.082612 (rank : 49)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	131	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JLH8	Gene names	Tmod4
Domain Architecture
Description	Tropomodulin-4 (Skeletal muscle tropomodulin) (Sk-Tmod).

TMOD3_MOUSE
NC score	0.079753 (rank : 50)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	131	Target Neighborhood Hits	34	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JHJ0, Q3TIT1	Gene names	Tmod3
Domain Architecture
Description	Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod).

MEFV_MOUSE
NC score	0.079689 (rank : 51)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	131	Target Neighborhood Hits	236	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

TMOD3_HUMAN
NC score	0.078024 (rank : 52)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	131	Target Neighborhood Hits	35	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NYL9, Q9NT43, Q9NZR0	Gene names	TMOD3
Domain Architecture
Description	Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod).

LMD1_HUMAN
NC score	0.076417 (rank : 53)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	131	Target Neighborhood Hits	169	Shared Neighborhood Hits	18
SwissProt Accessions	P29536	Gene names	LMOD1
Domain Architecture
Description	Leiomodin-1 (Leiomodin, muscle form) (64 kDa autoantigen D1) (64 kDa autoantigen 1D) (64 kDa autoantigen 1D3) (Thyroid-associated ophthalmopathy autoantigen) (Smooth muscle leiomodin) (SM-Lmod).

CARD8_HUMAN
NC score	0.064189 (rank : 54)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	131	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2G2, Q6PGP8, Q96P82	Gene names	CARD8, KIAA0955, NDPP1
Domain Architecture
Description	Caspase recruitment domain-containing protein 8 (Apoptotic protein NDPP1) (DACAR) (CARD-inhibitor of NF-kappa-B-activating ligand) (CARDINAL) (Tumor-up-regulated CARD-containing antagonist of CASP9) (TUCAN).

LRC57_HUMAN
NC score	0.062920 (rank : 55)	θ value	1.38821 (rank : 70)
Query Neighborhood Hits	131	Target Neighborhood Hits	271	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N9N7, Q7Z2Z6, Q8N1T6	Gene names	LRRC57
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 57.

PS1C2_HUMAN
NC score	0.061700 (rank : 56)	θ value	1.38821 (rank : 72)
Query Neighborhood Hits	131	Target Neighborhood Hits	66	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UIG4	Gene names	PSORS1C2, C6orf17, SPR1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein precursor (SPR1 protein).

LRC57_MOUSE
NC score	0.058266 (rank : 57)	θ value	1.38821 (rank : 71)
Query Neighborhood Hits	131	Target Neighborhood Hits	267	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D1G5, Q9DC95	Gene names	Lrrc57
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 57.

LRC41_HUMAN
NC score	0.057413 (rank : 58)	θ value	1.38821 (rank : 69)
Query Neighborhood Hits	131	Target Neighborhood Hits	51	Shared Neighborhood Hits	16
SwissProt Accessions	Q15345, Q71RA8, Q9BSM0	Gene names	LRRC41, MUF1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 41 (Protein Muf1).

TLR9_MOUSE
NC score	0.053868 (rank : 59)	θ value	0.279714 (rank : 42)
Query Neighborhood Hits	131	Target Neighborhood Hits	291	Shared Neighborhood Hits	40
SwissProt Accessions	Q9EQU3, Q99MF2, Q99MQ8	Gene names	Tlr9
Domain Architecture
Description	Toll-like receptor 9 precursor (CD289 antigen).

LRC47_HUMAN
NC score	0.052878 (rank : 60)	θ value	1.06291 (rank : 64)
Query Neighborhood Hits	131	Target Neighborhood Hits	300	Shared Neighborhood Hits	37
SwissProt Accessions	Q8N1G4, Q9ULN5	Gene names	LRRC47, KIAA1185
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 47.

LRC47_MOUSE
NC score	0.052652 (rank : 61)	θ value	1.81305 (rank : 73)
Query Neighborhood Hits	131	Target Neighborhood Hits	299	Shared Neighborhood Hits	36
SwissProt Accessions	Q505F5, Q3U380, Q6ZPW2, Q9CUZ0	Gene names	Lrrc47, Kiaa1185
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 47.

RU2A_HUMAN
NC score	0.051464 (rank : 62)	θ value	0.365318 (rank : 44)
Query Neighborhood Hits	131	Target Neighborhood Hits	130	Shared Neighborhood Hits	18
SwissProt Accessions	P09661, Q8TBD2	Gene names	SNRPA1
Domain Architecture	No domain graphic available
Description	U2 small nuclear ribonucleoprotein A' (U2 snRNP-A').

LRC14_HUMAN
NC score	0.051408 (rank : 63)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	131	Target Neighborhood Hits	57	Shared Neighborhood Hits	21
SwissProt Accessions	Q15048	Gene names	LRRC14, KIAA0014
Domain Architecture
Description	Leucine-rich repeat-containing protein 14.

LRC41_MOUSE
NC score	0.050796 (rank : 64)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	131	Target Neighborhood Hits	37	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K1C9, Q91VX4	Gene names	Lrrc41, Muf1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 41 (Protein Muf1).

TLR9_HUMAN
NC score	0.049038 (rank : 65)	θ value	0.47712 (rank : 54)
Query Neighborhood Hits	131	Target Neighborhood Hits	295	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NR96, Q6UVZ2, Q9HD68, Q9HD69, Q9HD70, Q9NYC2, Q9NYC3	Gene names	TLR9
Domain Architecture
Description	Toll-like receptor 9 precursor (CD289 antigen).

KERA_HUMAN
NC score	0.048313 (rank : 66)	θ value	0.47712 (rank : 50)
Query Neighborhood Hits	131	Target Neighborhood Hits	275	Shared Neighborhood Hits	30
SwissProt Accessions	O60938	Gene names	KERA
Domain Architecture
Description	Keratocan precursor (KTN) (Keratan sulfate proteoglycan keratocan).

KERA_MOUSE
NC score	0.048212 (rank : 67)	θ value	0.21417 (rank : 40)
Query Neighborhood Hits	131	Target Neighborhood Hits	264	Shared Neighborhood Hits	28
SwissProt Accessions	O35367	Gene names	Kera, Ktcn
Domain Architecture
Description	Keratocan precursor (KTN) (Keratan sulfate proteoglycan keratocan).

ASPN_HUMAN
NC score	0.047454 (rank : 68)	θ value	0.47712 (rank : 47)
Query Neighborhood Hits	131	Target Neighborhood Hits	274	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BXN1, Q96K79, Q96LD0, Q9NXP3	Gene names	ASPN, PLAP1
Domain Architecture
Description	Asporin precursor (Periodontal ligament-associated protein 1) (PLAP- 1).

ECM2_HUMAN
NC score	0.046804 (rank : 69)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	131	Target Neighborhood Hits	402	Shared Neighborhood Hits	37
SwissProt Accessions	O94769	Gene names	ECM2
Domain Architecture
Description	Extracellular matrix protein 2 precursor (Matrix glycoprotein SC1/ECM2).

CEP72_MOUSE
NC score	0.046570 (rank : 70)	θ value	0.813845 (rank : 58)
Query Neighborhood Hits	131	Target Neighborhood Hits	381	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D3R3, Q8BM53, Q9D0B7	Gene names	Cep72
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

SMOO_HUMAN
NC score	0.044855 (rank : 71)	θ value	0.365318 (rank : 45)
Query Neighborhood Hits	131	Target Neighborhood Hits	391	Shared Neighborhood Hits	14
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

CEP72_HUMAN
NC score	0.044097 (rank : 72)	θ value	1.06291 (rank : 62)
Query Neighborhood Hits	131	Target Neighborhood Hits	374	Shared Neighborhood Hits	16
SwissProt Accessions	Q9P209, Q9BV03, Q9BWM3, Q9NVR4	Gene names	CEP72, KIAA1519
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

OMD_HUMAN
NC score	0.042862 (rank : 73)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	131	Target Neighborhood Hits	275	Shared Neighborhood Hits	30
SwissProt Accessions	Q99983	Gene names	OMD
Domain Architecture
Description	Osteomodulin precursor (Osteoadherin) (OSAD) (Keratan sulfate proteoglycan osteomodulin) (KSPG osteomodulin).

LRC40_MOUSE
NC score	0.042427 (rank : 74)	θ value	5.27518 (rank : 98)
Query Neighborhood Hits	131	Target Neighborhood Hits	311	Shared Neighborhood Hits	41
SwissProt Accessions	Q9CRC8, Q78WQ9, Q8BS83	Gene names	Lrrc40
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 40.

LRSM1_MOUSE
NC score	0.041644 (rank : 75)	θ value	0.279714 (rank : 41)
Query Neighborhood Hits	131	Target Neighborhood Hits	874	Shared Neighborhood Hits	35
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

DGCR8_MOUSE
NC score	0.041627 (rank : 76)	θ value	1.06291 (rank : 63)
Query Neighborhood Hits	131	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EQM6	Gene names	Dgcr8
Domain Architecture	No domain graphic available
Description	DGCR8 protein (DiGeorge syndrome critical region 8 homolog) (Gy1).

DGCR8_HUMAN
NC score	0.041266 (rank : 77)	θ value	1.38821 (rank : 67)
Query Neighborhood Hits	131	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WYQ5, Q6DCB2, Q6MZE9, Q6Y2L0, Q96G39, Q96GP8, Q9H6L8, Q9H6T7, Q9NRW2	Gene names	DGCR8, C22orf12, DGCRK6
Domain Architecture
Description	DGCR8 protein (DiGeorge syndrome critical region 8).

SLIT2_MOUSE
NC score	0.041041 (rank : 78)	θ value	0.62314 (rank : 55)
Query Neighborhood Hits	131	Target Neighborhood Hits	684	Shared Neighborhood Hits	36
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

ASPN_MOUSE
NC score	0.040971 (rank : 79)	θ value	4.03905 (rank : 89)
Query Neighborhood Hits	131	Target Neighborhood Hits	277	Shared Neighborhood Hits	32
SwissProt Accessions	Q99MQ4, Q9D6A2	Gene names	Aspn
Domain Architecture
Description	Asporin precursor.

SLIT1_HUMAN
NC score	0.039817 (rank : 80)	θ value	0.125558 (rank : 37)
Query Neighborhood Hits	131	Target Neighborhood Hits	700	Shared Neighborhood Hits	35
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

PRELP_MOUSE
NC score	0.039581 (rank : 81)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	131	Target Neighborhood Hits	295	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JK53	Gene names	Prelp
Domain Architecture
Description	Prolargin precursor (Proline-arginine-rich end leucine-rich repeat protein).

PGS1_MOUSE
NC score	0.039386 (rank : 82)	θ value	2.36792 (rank : 77)
Query Neighborhood Hits	131	Target Neighborhood Hits	265	Shared Neighborhood Hits	30
SwissProt Accessions	P28653, Q61355	Gene names	Bgn
Domain Architecture
Description	Biglycan precursor (Bone/cartilage proteoglycan I) (PG-S1).

SLIT1_MOUSE
NC score	0.039170 (rank : 83)	θ value	0.125558 (rank : 38)
Query Neighborhood Hits	131	Target Neighborhood Hits	715	Shared Neighborhood Hits	34
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

RU2A_MOUSE
NC score	0.038934 (rank : 84)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	131	Target Neighborhood Hits	131	Shared Neighborhood Hits	18
SwissProt Accessions	P57784, Q3U7R8, Q8K2W4, Q91YW1, Q9JKQ3	Gene names	Snrpa1
Domain Architecture	No domain graphic available
Description	U2 small nuclear ribonucleoprotein A' (U2 snRNP-A').

TLR1_HUMAN
NC score	0.038921 (rank : 85)	θ value	0.47712 (rank : 53)
Query Neighborhood Hits	131	Target Neighborhood Hits	280	Shared Neighborhood Hits	31
SwissProt Accessions	Q15399, O15452, Q9UG90	Gene names	TLR1, KIAA0012
Domain Architecture
Description	Toll-like receptor 1 precursor (Toll/interleukin-1 receptor-like protein) (TIL) (CD281 antigen).

PRELP_HUMAN
NC score	0.038574 (rank : 86)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	131	Target Neighborhood Hits	295	Shared Neighborhood Hits	28
SwissProt Accessions	P51888	Gene names	PRELP
Domain Architecture
Description	Prolargin precursor (Proline-arginine-rich end leucine-rich repeat protein).

FA62A_MOUSE
NC score	0.038271 (rank : 87)	θ value	0.125558 (rank : 36)
Query Neighborhood Hits	131	Target Neighborhood Hits	155	Shared Neighborhood Hits	4
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

VACHT_MOUSE
NC score	0.034359 (rank : 88)	θ value	0.163984 (rank : 39)
Query Neighborhood Hits	131	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	O35304	Gene names	Slc18a3, Vacht
Domain Architecture
Description	Vesicular acetylcholine transporter (VAChT) (Solute carrier family 18 member 3).

SLIT2_HUMAN
NC score	0.034118 (rank : 89)	θ value	2.36792 (rank : 79)
Query Neighborhood Hits	131	Target Neighborhood Hits	708	Shared Neighborhood Hits	34
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

RSU1_HUMAN
NC score	0.033778 (rank : 90)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	131	Target Neighborhood Hits	250	Shared Neighborhood Hits	31
SwissProt Accessions	Q15404	Gene names	RSU1, RSP1
Domain Architecture
Description	Ras suppressor protein 1 (Rsu-1) (RSP-1).

SLIT3_HUMAN
NC score	0.033604 (rank : 91)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	131	Target Neighborhood Hits	682	Shared Neighborhood Hits	34
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

SLIT3_MOUSE
NC score	0.032600 (rank : 92)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	131	Target Neighborhood Hits	700	Shared Neighborhood Hits	34
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

FA62A_HUMAN
NC score	0.031758 (rank : 93)	θ value	1.38821 (rank : 68)
Query Neighborhood Hits	131	Target Neighborhood Hits	168	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

SYNJ1_HUMAN
NC score	0.031302 (rank : 94)	θ value	0.47712 (rank : 52)
Query Neighborhood Hits	131	Target Neighborhood Hits	498	Shared Neighborhood Hits	11
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TAF3_HUMAN
NC score	0.031277 (rank : 95)	θ value	0.365318 (rank : 46)
Query Neighborhood Hits	131	Target Neighborhood Hits	568	Shared Neighborhood Hits	9
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

K1543_HUMAN
NC score	0.029931 (rank : 96)	θ value	0.813845 (rank : 59)
Query Neighborhood Hits	131	Target Neighborhood Hits	435	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

CABYR_HUMAN
NC score	0.026000 (rank : 97)	θ value	2.36792 (rank : 76)
Query Neighborhood Hits	131	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	O75952, Q8WXW5, Q9HAY3, Q9HAY4, Q9HAY5, Q9HCY9	Gene names	CABYR, CBP86, FSP2
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86) (Fibrousheathin-2) (FSP-2).

PHLB1_HUMAN
NC score	0.025519 (rank : 98)	θ value	0.813845 (rank : 60)
Query Neighborhood Hits	131	Target Neighborhood Hits	1038	Shared Neighborhood Hits	14
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

LRC56_MOUSE
NC score	0.024641 (rank : 99)	θ value	4.03905 (rank : 91)
Query Neighborhood Hits	131	Target Neighborhood Hits	100	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K375, Q571F2	Gene names	Lrrc56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

ATX1_MOUSE
NC score	0.024310 (rank : 100)	θ value	1.38821 (rank : 65)
Query Neighborhood Hits	131	Target Neighborhood Hits	264	Shared Neighborhood Hits	4
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

PEO1_MOUSE
NC score	0.023512 (rank : 101)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	131	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CIW5, Q8K1Z1	Gene names	Peo1
Domain Architecture	No domain graphic available
Description	Twinkle protein, mitochondrial precursor (EC 3.6.1.-) (T7 gp4-like protein with intramitochondrial nucleoid localization) (T7-like mitochondrial DNA helicase) (Progressive external ophthalmoplegia 1 protein homolog).

PHLB1_MOUSE
NC score	0.022981 (rank : 102)	θ value	4.03905 (rank : 92)
Query Neighborhood Hits	131	Target Neighborhood Hits	678	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

MIA2_MOUSE
NC score	0.022950 (rank : 103)	θ value	3.0926 (rank : 84)
Query Neighborhood Hits	131	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q91ZV0	Gene names	Mia2
Domain Architecture	No domain graphic available
Description	Melanoma inhibitory activity protein 2 precursor.

SOS1_HUMAN
NC score	0.022211 (rank : 104)	θ value	1.81305 (rank : 74)
Query Neighborhood Hits	131	Target Neighborhood Hits	274	Shared Neighborhood Hits	5
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

K0319_HUMAN
NC score	0.020599 (rank : 105)	θ value	3.0926 (rank : 82)
Query Neighborhood Hits	131	Target Neighborhood Hits	154	Shared Neighborhood Hits	9
SwissProt Accessions	Q5VV43, Q9UJC8, Q9Y4G7	Gene names	KIAA0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

ZFYV1_HUMAN
NC score	0.020290 (rank : 106)	θ value	3.0926 (rank : 88)
Query Neighborhood Hits	131	Target Neighborhood Hits	166	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

TBCE_HUMAN
NC score	0.019607 (rank : 107)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	131	Target Neighborhood Hits	141	Shared Neighborhood Hits	18
SwissProt Accessions	Q15813	Gene names	TBCE
Domain Architecture	No domain graphic available
Description	Tubulin-specific chaperone E (Tubulin-folding cofactor E).

BAZ2A_MOUSE
NC score	0.019541 (rank : 108)	θ value	0.813845 (rank : 56)
Query Neighborhood Hits	131	Target Neighborhood Hits	744	Shared Neighborhood Hits	15
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

CO039_HUMAN
NC score	0.018812 (rank : 109)	θ value	3.0926 (rank : 80)
Query Neighborhood Hits	131	Target Neighborhood Hits	264	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

SOS1_MOUSE
NC score	0.018741 (rank : 110)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	131	Target Neighborhood Hits	281	Shared Neighborhood Hits	6
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

ZFYV1_MOUSE
NC score	0.018458 (rank : 111)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	131	Target Neighborhood Hits	153	Shared Neighborhood Hits	3
SwissProt Accessions	Q810J8	Gene names	Zfyve1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1.

F51A1_HUMAN
NC score	0.016932 (rank : 112)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	131	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NWZ8	Gene names	FAM51A1
Domain Architecture	No domain graphic available
Description	Protein FAM51A1.

FA8_HUMAN
NC score	0.016582 (rank : 113)	θ value	3.0926 (rank : 81)
Query Neighborhood Hits	131	Target Neighborhood Hits	112	Shared Neighborhood Hits	6
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

K0226_HUMAN
NC score	0.015789 (rank : 114)	θ value	5.27518 (rank : 97)
Query Neighborhood Hits	131	Target Neighborhood Hits	92	Shared Neighborhood Hits	6
SwissProt Accessions	Q92622	Gene names	KIAA0226
Domain Architecture	No domain graphic available
Description	Protein KIAA0226.

MCES_MOUSE
NC score	0.013827 (rank : 115)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	131	Target Neighborhood Hits	88	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D0L8, Q3V3U9, Q6ZQC6, Q9D5F1	Gene names	Rnmt, Kiaa0398
Domain Architecture	No domain graphic available
Description	mRNA cap guanine-N7 methyltransferase (EC 2.1.1.56) (mRNA (guanine- N(7)-)-methyltransferase) (RG7MT1) (mRNA cap methyltransferase).

TXND2_HUMAN
NC score	0.013672 (rank : 116)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	131	Target Neighborhood Hits	793	Shared Neighborhood Hits	13
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

GPNMB_HUMAN
NC score	0.013480 (rank : 117)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	131	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q14956, Q6UVX1, Q8N1A1	Gene names	GPNMB, HGFIN, NMB
Domain Architecture
Description	Transmembrane glycoprotein NMB precursor (Transmembrane glycoprotein HGFIN).

SRRM2_HUMAN
NC score	0.013371 (rank : 118)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	131	Target Neighborhood Hits	1296	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

OS9_HUMAN
NC score	0.013261 (rank : 119)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	131	Target Neighborhood Hits	134	Shared Neighborhood Hits	5
SwissProt Accessions	Q13438, O00579	Gene names	OS9
Domain Architecture	No domain graphic available
Description	Protein OS-9 precursor (Amplified in osteosarcoma 9).

RGS3_MOUSE
NC score	0.012956 (rank : 120)	θ value	0.47712 (rank : 51)
Query Neighborhood Hits	131	Target Neighborhood Hits	1621	Shared Neighborhood Hits	23
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

MLL2_HUMAN
NC score	0.012340 (rank : 121)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	131	Target Neighborhood Hits	1788	Shared Neighborhood Hits	26
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

ALDR_MOUSE
NC score	0.012030 (rank : 122)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	131	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	P45376, O70130, Q99KC9	Gene names	Akr1b1, Akr1b3, Aldor1, Aldr1
Domain Architecture
Description	Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase).

RPGR1_MOUSE
NC score	0.011734 (rank : 123)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	131	Target Neighborhood Hits	713	Shared Neighborhood Hits	11
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

RHG09_HUMAN
NC score	0.011381 (rank : 124)	θ value	2.36792 (rank : 78)
Query Neighborhood Hits	131	Target Neighborhood Hits	186	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

ZC11A_HUMAN
NC score	0.011330 (rank : 125)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	131	Target Neighborhood Hits	170	Shared Neighborhood Hits	2
SwissProt Accessions	O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7	Gene names	ZC3H11A, KIAA0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

WFS1_HUMAN
NC score	0.010480 (rank : 126)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	131	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	O76024, Q8N6I3, Q9UNW6	Gene names	WFS1
Domain Architecture	No domain graphic available
Description	Wolframin.

BBS4_HUMAN
NC score	0.010270 (rank : 127)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	131	Target Neighborhood Hits	109	Shared Neighborhood Hits	3
SwissProt Accessions	Q96RK4, Q8NHU9, Q96H45	Gene names	BBS4
Domain Architecture
Description	Bardet-Biedl syndrome 4 protein.

LIPA3_HUMAN
NC score	0.010214 (rank : 128)	θ value	3.0926 (rank : 83)
Query Neighborhood Hits	131	Target Neighborhood Hits	828	Shared Neighborhood Hits	12
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

TNR3_MOUSE
NC score	0.009983 (rank : 129)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	131	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

GA2L1_MOUSE
NC score	0.009886 (rank : 130)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	131	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

HSF1_MOUSE
NC score	0.008475 (rank : 131)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	131	Target Neighborhood Hits	267	Shared Neighborhood Hits	7
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

FBLN2_MOUSE
NC score	0.007331 (rank : 132)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	131	Target Neighborhood Hits	505	Shared Neighborhood Hits	18
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

STAM1_HUMAN
NC score	0.007270 (rank : 133)	θ value	4.03905 (rank : 94)
Query Neighborhood Hits	131	Target Neighborhood Hits	271	Shared Neighborhood Hits	3
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

POT15_HUMAN
NC score	0.006847 (rank : 134)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	131	Target Neighborhood Hits	893	Shared Neighborhood Hits	13
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

ANR21_HUMAN
NC score	0.006714 (rank : 135)	θ value	5.27518 (rank : 96)
Query Neighborhood Hits	131	Target Neighborhood Hits	864	Shared Neighborhood Hits	13
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

ALDR_HUMAN
NC score	0.006236 (rank : 136)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	131	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P15121, Q9BS21, Q9UCI9	Gene names	AKR1B1, ALDR1
Domain Architecture
Description	Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase).

HECD1_HUMAN
NC score	0.004603 (rank : 137)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	131	Target Neighborhood Hits	371	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

HGFA_HUMAN
NC score	0.003996 (rank : 138)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	131	Target Neighborhood Hits	436	Shared Neighborhood Hits	9
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

SPEG_HUMAN
NC score	-0.001306 (rank : 139)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	131	Target Neighborhood Hits	1762	Shared Neighborhood Hits	21
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

STK10_MOUSE
NC score	-0.001471 (rank : 140)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	131	Target Neighborhood Hits	2132	Shared Neighborhood Hits	18
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).