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Network neighborhood for query Sequence : GA2L1_MOUSE

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GA2L1_MOUSE
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GA2L1_HUMAN
θ value	0 (rank : 1)	NC score	0.953169 (rank : 2)
Query Neighborhood Hits	114	Target Neighborhood Hits	177	Shared Neighborhood Hits	55
SwissProt Accessions	Q99501, Q53EN7, Q92640, Q9BUY9	Gene names	GAS2L1, GAR22
Domain Architecture
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1) (GAS2-related protein on chromosome 22) (GAR22 protein).

GA2L1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	114	Target Neighborhood Hits	114	Shared Neighborhood Hits	114
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

GA2L2_MOUSE
θ value	1.66191e-70 (rank : 3)	NC score	0.817501 (rank : 6)
Query Neighborhood Hits	114	Target Neighborhood Hits	395	Shared Neighborhood Hits	43
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

GA2L2_HUMAN
θ value	5.17823e-64 (rank : 4)	NC score	0.876083 (rank : 3)
Query Neighborhood Hits	114	Target Neighborhood Hits	175	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NHY3, Q8NHY4	Gene names	GAS2L2, GAR17
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2) (GAS2-related protein on chromosome 17) (GAR17 protein).

GAS2_HUMAN
θ value	8.06329e-33 (rank : 5)	NC score	0.832105 (rank : 5)
Query Neighborhood Hits	114	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	O43903, Q6ICV8	Gene names	GAS2
Domain Architecture
Description	Growth-arrest-specific protein 2 (GAS-2).

GAS2_MOUSE
θ value	6.82597e-32 (rank : 6)	NC score	0.832377 (rank : 4)
Query Neighborhood Hits	114	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	P11862	Gene names	Gas2, Gas-2
Domain Architecture
Description	Growth-arrest-specific protein 2 (GAS-2).

GA2L3_HUMAN
θ value	1.28732e-30 (rank : 7)	NC score	0.772752 (rank : 7)
Query Neighborhood Hits	114	Target Neighborhood Hits	189	Shared Neighborhood Hits	29
SwissProt Accessions	Q86XJ1	Gene names	GAS2L3
Domain Architecture	No domain graphic available
Description	GAS2-like protein 3 (Growth arrest-specific 2-like 3).

MACF1_HUMAN
θ value	4.91457e-14 (rank : 8)	NC score	0.248424 (rank : 10)
Query Neighborhood Hits	114	Target Neighborhood Hits	1341	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF1_MOUSE
θ value	4.59992e-12 (rank : 9)	NC score	0.243034 (rank : 11)
Query Neighborhood Hits	114	Target Neighborhood Hits	1313	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

MACF4_HUMAN
θ value	4.59992e-12 (rank : 10)	NC score	0.267491 (rank : 8)
Query Neighborhood Hits	114	Target Neighborhood Hits	1321	Shared Neighborhood Hits	32
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

BPAEA_HUMAN
θ value	6.00763e-12 (rank : 11)	NC score	0.256536 (rank : 9)
Query Neighborhood Hits	114	Target Neighborhood Hits	1369	Shared Neighborhood Hits	30
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BPA1_MOUSE
θ value	2.28291e-11 (rank : 12)	NC score	0.224243 (rank : 12)
Query Neighborhood Hits	114	Target Neighborhood Hits	1477	Shared Neighborhood Hits	35
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

TARA_HUMAN
θ value	3.19293e-05 (rank : 13)	NC score	0.126456 (rank : 13)
Query Neighborhood Hits	114	Target Neighborhood Hits	1626	Shared Neighborhood Hits	55
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TSNA1_HUMAN
θ value	0.00175202 (rank : 14)	NC score	0.091984 (rank : 26)
Query Neighborhood Hits	114	Target Neighborhood Hits	178	Shared Neighborhood Hits	11
SwissProt Accessions	Q96NA8	Gene names	TSNARE1
Domain Architecture	No domain graphic available
Description	t-SNARE domain-containing protein 1.

CDKL5_HUMAN
θ value	0.00298849 (rank : 15)	NC score	0.017049 (rank : 172)
Query Neighborhood Hits	114	Target Neighborhood Hits	967	Shared Neighborhood Hits	19
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

MAGE1_HUMAN
θ value	0.00390308 (rank : 16)	NC score	0.058064 (rank : 94)
Query Neighborhood Hits	114	Target Neighborhood Hits	1389	Shared Neighborhood Hits	57
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

KI67_HUMAN
θ value	0.00665767 (rank : 17)	NC score	0.092589 (rank : 25)
Query Neighborhood Hits	114	Target Neighborhood Hits	581	Shared Neighborhood Hits	28
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

MAST4_HUMAN
θ value	0.0113563 (rank : 18)	NC score	0.027981 (rank : 157)
Query Neighborhood Hits	114	Target Neighborhood Hits	1804	Shared Neighborhood Hits	62
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

IASPP_MOUSE
θ value	0.0148317 (rank : 19)	NC score	0.067071 (rank : 70)
Query Neighborhood Hits	114	Target Neighborhood Hits	1024	Shared Neighborhood Hits	40
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ANK2_HUMAN
θ value	0.0330416 (rank : 20)	NC score	0.050800 (rank : 120)
Query Neighborhood Hits	114	Target Neighborhood Hits	1615	Shared Neighborhood Hits	62
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

SRRM2_MOUSE
θ value	0.0330416 (rank : 21)	NC score	0.118830 (rank : 14)
Query Neighborhood Hits	114	Target Neighborhood Hits	1470	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

BAT2_MOUSE
θ value	0.0563607 (rank : 22)	NC score	0.099824 (rank : 21)
Query Neighborhood Hits	114	Target Neighborhood Hits	947	Shared Neighborhood Hits	49
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CO5A2_HUMAN
θ value	0.0563607 (rank : 23)	NC score	0.036045 (rank : 140)
Query Neighborhood Hits	114	Target Neighborhood Hits	760	Shared Neighborhood Hits	34
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

TARA_MOUSE
θ value	0.0563607 (rank : 24)	NC score	0.103633 (rank : 18)
Query Neighborhood Hits	114	Target Neighborhood Hits	1133	Shared Neighborhood Hits	52
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

MDC1_MOUSE
θ value	0.0736092 (rank : 25)	NC score	0.090377 (rank : 27)
Query Neighborhood Hits	114	Target Neighborhood Hits	998	Shared Neighborhood Hits	51
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

PRGR_HUMAN
θ value	0.0961366 (rank : 26)	NC score	0.020715 (rank : 169)
Query Neighborhood Hits	114	Target Neighborhood Hits	163	Shared Neighborhood Hits	8
SwissProt Accessions	P06401, Q9UPF7	Gene names	PGR, NR3C3
Domain Architecture
Description	Progesterone receptor (PR).

SREC_HUMAN
θ value	0.0961366 (rank : 27)	NC score	0.015134 (rank : 176)
Query Neighborhood Hits	114	Target Neighborhood Hits	645	Shared Neighborhood Hits	15
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

MDC1_HUMAN
θ value	0.125558 (rank : 28)	NC score	0.093185 (rank : 24)
Query Neighborhood Hits	114	Target Neighborhood Hits	1446	Shared Neighborhood Hits	61
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

NIPBL_HUMAN
θ value	0.125558 (rank : 29)	NC score	0.061797 (rank : 83)
Query Neighborhood Hits	114	Target Neighborhood Hits	1311	Shared Neighborhood Hits	39
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

CAC1H_HUMAN
θ value	0.21417 (rank : 30)	NC score	0.030559 (rank : 151)
Query Neighborhood Hits	114	Target Neighborhood Hits	307	Shared Neighborhood Hits	19
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

TGON1_MOUSE
θ value	0.21417 (rank : 31)	NC score	0.078850 (rank : 40)
Query Neighborhood Hits	114	Target Neighborhood Hits	243	Shared Neighborhood Hits	20
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

IQGA1_HUMAN
θ value	0.279714 (rank : 32)	NC score	0.073768 (rank : 54)
Query Neighborhood Hits	114	Target Neighborhood Hits	250	Shared Neighborhood Hits	13
SwissProt Accessions	P46940	Gene names	IQGAP1, KIAA0051
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1 (p195).

IQGA1_MOUSE
θ value	0.279714 (rank : 33)	NC score	0.076436 (rank : 45)
Query Neighborhood Hits	114	Target Neighborhood Hits	219	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JKF1	Gene names	Iqgap1
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1.

RGS3_MOUSE
θ value	0.279714 (rank : 34)	NC score	0.043561 (rank : 131)
Query Neighborhood Hits	114	Target Neighborhood Hits	1621	Shared Neighborhood Hits	60
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

OGFR_HUMAN
θ value	0.365318 (rank : 35)	NC score	0.052621 (rank : 111)
Query Neighborhood Hits	114	Target Neighborhood Hits	1582	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

SPEG_MOUSE
θ value	0.365318 (rank : 36)	NC score	0.025735 (rank : 160)
Query Neighborhood Hits	114	Target Neighborhood Hits	1959	Shared Neighborhood Hits	54
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

BAT2_HUMAN
θ value	0.47712 (rank : 37)	NC score	0.104982 (rank : 16)
Query Neighborhood Hits	114	Target Neighborhood Hits	931	Shared Neighborhood Hits	58
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BCOR_MOUSE
θ value	0.47712 (rank : 38)	NC score	0.034524 (rank : 144)
Query Neighborhood Hits	114	Target Neighborhood Hits	521	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

GRIN1_HUMAN
θ value	0.47712 (rank : 39)	NC score	0.080053 (rank : 36)
Query Neighborhood Hits	114	Target Neighborhood Hits	681	Shared Neighborhood Hits	48
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

NPBL_MOUSE
θ value	0.47712 (rank : 40)	NC score	0.064798 (rank : 76)
Query Neighborhood Hits	114	Target Neighborhood Hits	1041	Shared Neighborhood Hits	39
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

CECR2_HUMAN
θ value	0.62314 (rank : 41)	NC score	0.033844 (rank : 146)
Query Neighborhood Hits	114	Target Neighborhood Hits	543	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

PRRT3_HUMAN
θ value	0.813845 (rank : 42)	NC score	0.053364 (rank : 106)
Query Neighborhood Hits	114	Target Neighborhood Hits	998	Shared Neighborhood Hits	46
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SPEG_HUMAN
θ value	0.813845 (rank : 43)	NC score	0.023765 (rank : 162)
Query Neighborhood Hits	114	Target Neighborhood Hits	1762	Shared Neighborhood Hits	56
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TTC16_HUMAN
θ value	0.813845 (rank : 44)	NC score	0.058031 (rank : 95)
Query Neighborhood Hits	114	Target Neighborhood Hits	417	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

AMOT_HUMAN
θ value	1.06291 (rank : 45)	NC score	0.039971 (rank : 135)
Query Neighborhood Hits	114	Target Neighborhood Hits	712	Shared Neighborhood Hits	26
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

CT2NL_MOUSE
θ value	1.06291 (rank : 46)	NC score	0.028314 (rank : 155)
Query Neighborhood Hits	114	Target Neighborhood Hits	902	Shared Neighborhood Hits	20
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

HRX_HUMAN
θ value	1.06291 (rank : 47)	NC score	0.038786 (rank : 136)
Query Neighborhood Hits	114	Target Neighborhood Hits	825	Shared Neighborhood Hits	39
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

RUSC1_HUMAN
θ value	1.06291 (rank : 48)	NC score	0.028182 (rank : 156)
Query Neighborhood Hits	114	Target Neighborhood Hits	226	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

CAMKV_HUMAN
θ value	1.38821 (rank : 49)	NC score	0.016210 (rank : 173)
Query Neighborhood Hits	114	Target Neighborhood Hits	1084	Shared Neighborhood Hits	35
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

MARK2_MOUSE
θ value	1.38821 (rank : 50)	NC score	0.010173 (rank : 187)
Query Neighborhood Hits	114	Target Neighborhood Hits	1018	Shared Neighborhood Hits	22
SwissProt Accessions	Q05512, Q6PDR4, Q8BR95	Gene names	Mark2, Emk
Domain Architecture
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1).

NU214_HUMAN
θ value	1.38821 (rank : 51)	NC score	0.057790 (rank : 96)
Query Neighborhood Hits	114	Target Neighborhood Hits	657	Shared Neighborhood Hits	39
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

CSKI1_MOUSE
θ value	1.81305 (rank : 52)	NC score	0.032830 (rank : 149)
Query Neighborhood Hits	114	Target Neighborhood Hits	1031	Shared Neighborhood Hits	44
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

PAK4_MOUSE
θ value	1.81305 (rank : 53)	NC score	0.010892 (rank : 184)
Query Neighborhood Hits	114	Target Neighborhood Hits	1098	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

BCOR_HUMAN
θ value	2.36792 (rank : 54)	NC score	0.035469 (rank : 142)
Query Neighborhood Hits	114	Target Neighborhood Hits	609	Shared Neighborhood Hits	20
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CAC1A_HUMAN
θ value	2.36792 (rank : 55)	NC score	0.035081 (rank : 143)
Query Neighborhood Hits	114	Target Neighborhood Hits	387	Shared Neighborhood Hits	36
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CASP8_HUMAN
θ value	2.36792 (rank : 56)	NC score	0.016129 (rank : 174)
Query Neighborhood Hits	114	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q14790, O14676, Q14791, Q14792, Q14793, Q14794, Q14795, Q14796, Q15780, Q15806, Q53TT5, Q8TDI1, Q8TDI2, Q8TDI3, Q8TDI4, Q8TDI5, Q96T22, Q9C0K4, Q9UQ81	Gene names	CASP8, MCH5
Domain Architecture
Description	Caspase-8 precursor (EC 3.4.22.-) (CASP-8) (ICE-like apoptotic protease 5) (MORT1-associated CED-3 homolog) (MACH) (FADD-homologous ICE/CED-3-like protease) (FADD-like ICE) (FLICE) (Apoptotic cysteine protease) (Apoptotic protease Mch-5) (CAP4) [Contains: Caspase-8 subunit p18; Caspase-8 subunit p10].

CO9A2_HUMAN
θ value	2.36792 (rank : 57)	NC score	0.030512 (rank : 152)
Query Neighborhood Hits	114	Target Neighborhood Hits	261	Shared Neighborhood Hits	22
SwissProt Accessions	Q14055	Gene names	COL9A2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

HAIR_MOUSE
θ value	2.36792 (rank : 58)	NC score	0.018303 (rank : 171)
Query Neighborhood Hits	114	Target Neighborhood Hits	97	Shared Neighborhood Hits	5
SwissProt Accessions	Q61645, Q80Y47	Gene names	Hr
Domain Architecture
Description	Protein hairless.

TAU_MOUSE
θ value	2.36792 (rank : 59)	NC score	0.050525 (rank : 122)
Query Neighborhood Hits	114	Target Neighborhood Hits	502	Shared Neighborhood Hits	38
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TGON2_MOUSE
θ value	2.36792 (rank : 60)	NC score	0.073267 (rank : 59)
Query Neighborhood Hits	114	Target Neighborhood Hits	277	Shared Neighborhood Hits	24
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

CO5A1_MOUSE
θ value	3.0926 (rank : 61)	NC score	0.036618 (rank : 138)
Query Neighborhood Hits	114	Target Neighborhood Hits	419	Shared Neighborhood Hits	36
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

CRTC1_MOUSE
θ value	3.0926 (rank : 62)	NC score	0.052350 (rank : 113)
Query Neighborhood Hits	114	Target Neighborhood Hits	230	Shared Neighborhood Hits	18
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

DLX5_MOUSE
θ value	3.0926 (rank : 63)	NC score	0.004420 (rank : 196)
Query Neighborhood Hits	114	Target Neighborhood Hits	434	Shared Neighborhood Hits	8
SwissProt Accessions	P70396, O54876, O54877, O54878, Q9JJ45	Gene names	Dlx5
Domain Architecture
Description	Homeobox protein DLX-5.

SHAN1_HUMAN
θ value	3.0926 (rank : 64)	NC score	0.033932 (rank : 145)
Query Neighborhood Hits	114	Target Neighborhood Hits	1041	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SMAL1_MOUSE
θ value	3.0926 (rank : 65)	NC score	0.014873 (rank : 177)
Query Neighborhood Hits	114	Target Neighborhood Hits	157	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

APXL_HUMAN
θ value	4.03905 (rank : 66)	NC score	0.044389 (rank : 130)
Query Neighborhood Hits	114	Target Neighborhood Hits	553	Shared Neighborhood Hits	37
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

CA147_HUMAN
θ value	4.03905 (rank : 67)	NC score	0.047400 (rank : 128)
Query Neighborhood Hits	114	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q96MC9, Q5JTS5	Gene names	C1orf147
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf147.

CAC1A_MOUSE
θ value	4.03905 (rank : 68)	NC score	0.026935 (rank : 158)
Query Neighborhood Hits	114	Target Neighborhood Hits	267	Shared Neighborhood Hits	26
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1H_MOUSE
θ value	4.03905 (rank : 69)	NC score	0.026788 (rank : 159)
Query Neighborhood Hits	114	Target Neighborhood Hits	230	Shared Neighborhood Hits	18
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CSF1_HUMAN
θ value	4.03905 (rank : 70)	NC score	0.041361 (rank : 133)
Query Neighborhood Hits	114	Target Neighborhood Hits	258	Shared Neighborhood Hits	27
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

CT128_HUMAN
θ value	4.03905 (rank : 71)	NC score	0.021197 (rank : 168)
Query Neighborhood Hits	114	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BQN1, Q5JWN6, Q8N276	Gene names	C20orf128
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf128.

CTG1B_HUMAN
θ value	4.03905 (rank : 72)	NC score	0.036083 (rank : 139)
Query Neighborhood Hits	114	Target Neighborhood Hits	61	Shared Neighborhood Hits	7
SwissProt Accessions	P78358, Q7LBY4	Gene names	CTAG1B, CTAG, CTAG1, ESO1, LAGE2
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen 1B (L antigen family member 2) (LAGE-2 protein) (Autoimmunogenic cancer/testis antigen NY-ESO-1).

DEN2A_HUMAN
θ value	4.03905 (rank : 73)	NC score	0.010712 (rank : 185)
Query Neighborhood Hits	114	Target Neighborhood Hits	83	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ULE3, Q1RMD5, Q86XY0	Gene names	DENND2A, KIAA1277
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

ICB1_MOUSE
θ value	4.03905 (rank : 74)	NC score	0.024504 (rank : 161)
Query Neighborhood Hits	114	Target Neighborhood Hits	69	Shared Neighborhood Hits	5
SwissProt Accessions	Q91YX0	Gene names	Icb1
Domain Architecture	No domain graphic available
Description	Induced by contact to basement membrane 1 protein homolog (ICB-1 protein).

IF4G3_MOUSE
θ value	4.03905 (rank : 75)	NC score	0.022311 (rank : 167)
Query Neighborhood Hits	114	Target Neighborhood Hits	279	Shared Neighborhood Hits	14
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

IL3B2_MOUSE
θ value	4.03905 (rank : 76)	NC score	0.022699 (rank : 165)
Query Neighborhood Hits	114	Target Neighborhood Hits	372	Shared Neighborhood Hits	18
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

NALP1_HUMAN
θ value	4.03905 (rank : 77)	NC score	0.010104 (rank : 188)
Query Neighborhood Hits	114	Target Neighborhood Hits	138	Shared Neighborhood Hits	9
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

RARA_HUMAN
θ value	4.03905 (rank : 78)	NC score	0.008809 (rank : 191)
Query Neighborhood Hits	114	Target Neighborhood Hits	118	Shared Neighborhood Hits	5
SwissProt Accessions	P10276, P78456, Q13440, Q13441, Q9NQS0	Gene names	RARA, NR1B1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

CRTC1_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.059601 (rank : 90)
Query Neighborhood Hits	114	Target Neighborhood Hits	319	Shared Neighborhood Hits	26
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

MILK1_MOUSE
θ value	5.27518 (rank : 80)	NC score	0.084143 (rank : 31)
Query Neighborhood Hits	114	Target Neighborhood Hits	788	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

TENS1_HUMAN
θ value	5.27518 (rank : 81)	NC score	0.033455 (rank : 148)
Query Neighborhood Hits	114	Target Neighborhood Hits	400	Shared Neighborhood Hits	26
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

TERF2_MOUSE
θ value	5.27518 (rank : 82)	NC score	0.020062 (rank : 170)
Query Neighborhood Hits	114	Target Neighborhood Hits	128	Shared Neighborhood Hits	11
SwissProt Accessions	O35144	Gene names	Terf2, Trf2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

TXLNB_HUMAN
θ value	5.27518 (rank : 83)	NC score	0.040590 (rank : 134)
Query Neighborhood Hits	114	Target Neighborhood Hits	912	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

ABL2_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.003871 (rank : 197)
Query Neighborhood Hits	114	Target Neighborhood Hits	1045	Shared Neighborhood Hits	21
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

ARRD1_HUMAN
θ value	6.88961 (rank : 85)	NC score	0.013193 (rank : 179)
Query Neighborhood Hits	114	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N5I2	Gene names	ARRDC1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

CAC1B_MOUSE
θ value	6.88961 (rank : 86)	NC score	0.023689 (rank : 163)
Query Neighborhood Hits	114	Target Neighborhood Hits	351	Shared Neighborhood Hits	28
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CNN3_MOUSE
θ value	6.88961 (rank : 87)	NC score	0.042435 (rank : 132)
Query Neighborhood Hits	114	Target Neighborhood Hits	45	Shared Neighborhood Hits	8
SwissProt Accessions	Q9DAW9, Q3TW23	Gene names	Cnn3
Domain Architecture	No domain graphic available
Description	Calponin-3 (Calponin, acidic isoform).

CSKI1_HUMAN
θ value	6.88961 (rank : 88)	NC score	0.035975 (rank : 141)
Query Neighborhood Hits	114	Target Neighborhood Hits	997	Shared Neighborhood Hits	52
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

DLG7_MOUSE
θ value	6.88961 (rank : 89)	NC score	0.016079 (rank : 175)
Query Neighborhood Hits	114	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K4R9, Q6ZQL3, Q80VS7, Q8BUC8, Q8BZ79	Gene names	Dlg7, Kiaa0008
Domain Architecture	No domain graphic available
Description	Discs large homolog 7 (Hepatoma up-regulated protein homolog) (HURP).

ES8L3_HUMAN
θ value	6.88961 (rank : 90)	NC score	0.013770 (rank : 178)
Query Neighborhood Hits	114	Target Neighborhood Hits	206	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

FBX41_HUMAN
θ value	6.88961 (rank : 91)	NC score	0.022725 (rank : 164)
Query Neighborhood Hits	114	Target Neighborhood Hits	475	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TF61	Gene names	FBXO41, FBX41, KIAA1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

PANK1_MOUSE
θ value	6.88961 (rank : 92)	NC score	0.008707 (rank : 192)
Query Neighborhood Hits	114	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K4K6, Q9D3K1, Q9QXM8	Gene names	Pank1, Pank
Domain Architecture
Description	Pantothenate kinase 1 (EC 2.7.1.33) (Pantothenic acid kinase 1) (mPank1) (mPank).

PDZD2_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.032583 (rank : 150)
Query Neighborhood Hits	114	Target Neighborhood Hits	772	Shared Neighborhood Hits	38
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

RPGF6_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.013107 (rank : 180)
Query Neighborhood Hits	114	Target Neighborhood Hits	266	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

S45A3_MOUSE
θ value	6.88961 (rank : 95)	NC score	0.012014 (rank : 182)
Query Neighborhood Hits	114	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K0H7, Q8K252, Q8R1I0	Gene names	Slc45a3, Pcanap6, Prst
Domain Architecture	No domain graphic available
Description	Solute carrier family 45 member 3 (Prostate cancer-associated protein 6) (Prostein).

SFRIP_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.056952 (rank : 97)
Query Neighborhood Hits	114	Target Neighborhood Hits	530	Shared Neighborhood Hits	29
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

TCF8_MOUSE
θ value	6.88961 (rank : 97)	NC score	-0.000751 (rank : 198)
Query Neighborhood Hits	114	Target Neighborhood Hits	1067	Shared Neighborhood Hits	13
SwissProt Accessions	Q64318, Q62519	Gene names	Tcf8, Zfhx1a, Zfx1a, Zfx1ha
Domain Architecture
Description	Transcription factor 8 (Zinc finger homeobox protein 1a) (MEB1) (Delta EF1).

ULK1_MOUSE
θ value	6.88961 (rank : 98)	NC score	0.008252 (rank : 193)
Query Neighborhood Hits	114	Target Neighborhood Hits	1214	Shared Neighborhood Hits	27
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

BAG3_HUMAN
θ value	8.99809 (rank : 99)	NC score	0.055673 (rank : 101)
Query Neighborhood Hits	114	Target Neighborhood Hits	314	Shared Neighborhood Hits	33
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

C2TA_MOUSE
θ value	8.99809 (rank : 100)	NC score	0.009886 (rank : 189)
Query Neighborhood Hits	114	Target Neighborhood Hits	131	Shared Neighborhood Hits	5
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).

CBL_HUMAN
θ value	8.99809 (rank : 101)	NC score	0.012795 (rank : 181)
Query Neighborhood Hits	114	Target Neighborhood Hits	353	Shared Neighborhood Hits	17
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CO5A1_HUMAN
θ value	8.99809 (rank : 102)	NC score	0.033774 (rank : 147)
Query Neighborhood Hits	114	Target Neighborhood Hits	434	Shared Neighborhood Hits	36
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

CTAG2_HUMAN
θ value	8.99809 (rank : 103)	NC score	0.028769 (rank : 154)
Query Neighborhood Hits	114	Target Neighborhood Hits	65	Shared Neighborhood Hits	8
SwissProt Accessions	O75638, O75637, Q9BU80, Q9UJ89, Q9Y479	Gene names	CTAG2, ESO2, LAGE1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen 2 (L antigen family member 1) (LAGE-1 protein) (ESO-2 protein).

CUTL2_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.029092 (rank : 153)
Query Neighborhood Hits	114	Target Neighborhood Hits	906	Shared Neighborhood Hits	34
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

DCBD1_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.005370 (rank : 195)
Query Neighborhood Hits	114	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DOT1L_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.075909 (rank : 47)
Query Neighborhood Hits	114	Target Neighborhood Hits	660	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

FBX41_MOUSE
θ value	8.99809 (rank : 107)	NC score	0.022539 (rank : 166)
Query Neighborhood Hits	114	Target Neighborhood Hits	430	Shared Neighborhood Hits	15
SwissProt Accessions	Q6NS60, Q6P7W4, Q6ZPG1	Gene names	Fbxo41, D6Ertd538e, Kiaa1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

GOGA3_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.044957 (rank : 129)
Query Neighborhood Hits	114	Target Neighborhood Hits	1317	Shared Neighborhood Hits	29
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

JIP3_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.011885 (rank : 183)
Query Neighborhood Hits	114	Target Neighborhood Hits	1039	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

K1802_MOUSE
θ value	8.99809 (rank : 110)	NC score	0.038521 (rank : 137)
Query Neighborhood Hits	114	Target Neighborhood Hits	1596	Shared Neighborhood Hits	51
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

M3K9_HUMAN
θ value	8.99809 (rank : 111)	NC score	0.005561 (rank : 194)
Query Neighborhood Hits	114	Target Neighborhood Hits	1123	Shared Neighborhood Hits	23
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

NACAM_MOUSE
θ value	8.99809 (rank : 112)	NC score	0.073710 (rank : 55)
Query Neighborhood Hits	114	Target Neighborhood Hits	1866	Shared Neighborhood Hits	70
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PP4R1_MOUSE
θ value	8.99809 (rank : 113)	NC score	0.009783 (rank : 190)
Query Neighborhood Hits	114	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K2V1, Q8R0R8	Gene names	Ppp4r1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

ULK1_HUMAN
θ value	8.99809 (rank : 114)	NC score	0.010245 (rank : 186)
Query Neighborhood Hits	114	Target Neighborhood Hits	1121	Shared Neighborhood Hits	30
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

ACTN1_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.062179 (rank : 80)
Query Neighborhood Hits	114	Target Neighborhood Hits	221	Shared Neighborhood Hits	7
SwissProt Accessions	P12814, Q9BTN1	Gene names	ACTN1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

ACTN1_MOUSE
θ value	θ > 10 (rank : 116)	NC score	0.062638 (rank : 79)
Query Neighborhood Hits	114	Target Neighborhood Hits	216	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TPR4	Gene names	Actn1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

ACTN2_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.060320 (rank : 89)
Query Neighborhood Hits	114	Target Neighborhood Hits	295	Shared Neighborhood Hits	7
SwissProt Accessions	P35609, Q86TF4, Q86TI8	Gene names	ACTN2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

ACTN2_MOUSE
θ value	θ > 10 (rank : 118)	NC score	0.061941 (rank : 82)
Query Neighborhood Hits	114	Target Neighborhood Hits	287	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JI91	Gene names	Actn2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

ACTN3_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.060672 (rank : 87)
Query Neighborhood Hits	114	Target Neighborhood Hits	272	Shared Neighborhood Hits	7
SwissProt Accessions	Q08043	Gene names	ACTN3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

ACTN3_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.063438 (rank : 78)
Query Neighborhood Hits	114	Target Neighborhood Hits	265	Shared Neighborhood Hits	9
SwissProt Accessions	O88990	Gene names	Actn3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

ACTN4_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.061523 (rank : 84)
Query Neighborhood Hits	114	Target Neighborhood Hits	279	Shared Neighborhood Hits	8
SwissProt Accessions	O43707, O76048	Gene names	ACTN4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

ACTN4_MOUSE
θ value	θ > 10 (rank : 122)	NC score	0.062065 (rank : 81)
Query Neighborhood Hits	114	Target Neighborhood Hits	276	Shared Neighborhood Hits	7
SwissProt Accessions	P57780	Gene names	Actn4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

AKAP6_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.065973 (rank : 73)
Query Neighborhood Hits	114	Target Neighborhood Hits	263	Shared Neighborhood Hits	12
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

ALEX_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.050090 (rank : 127)
Query Neighborhood Hits	114	Target Neighborhood Hits	361	Shared Neighborhood Hits	29
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ATN1_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.051342 (rank : 118)
Query Neighborhood Hits	114	Target Neighborhood Hits	676	Shared Neighborhood Hits	37
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BAG3_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.073561 (rank : 57)
Query Neighborhood Hits	114	Target Neighborhood Hits	513	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

BASP_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.055621 (rank : 102)
Query Neighborhood Hits	114	Target Neighborhood Hits	321	Shared Neighborhood Hits	28
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BASP_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.060880 (rank : 86)
Query Neighborhood Hits	114	Target Neighborhood Hits	260	Shared Neighborhood Hits	28
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BPAEA_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.104658 (rank : 17)
Query Neighborhood Hits	114	Target Neighborhood Hits	1480	Shared Neighborhood Hits	24
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BSN_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.056547 (rank : 98)
Query Neighborhood Hits	114	Target Neighborhood Hits	2057	Shared Neighborhood Hits	74
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CAYP1_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.052176 (rank : 114)
Query Neighborhood Hits	114	Target Neighborhood Hits	94	Shared Neighborhood Hits	5
SwissProt Accessions	Q13938, Q3MJA7, Q8WUZ3	Gene names	CAPS
Domain Architecture
Description	Calcyphosin (Calcyphosine).

CJ078_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.050461 (rank : 123)
Query Neighborhood Hits	114	Target Neighborhood Hits	559	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CK024_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.052838 (rank : 110)
Query Neighborhood Hits	114	Target Neighborhood Hits	408	Shared Neighborhood Hits	31
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CLMN_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.065034 (rank : 74)
Query Neighborhood Hits	114	Target Neighborhood Hits	205	Shared Neighborhood Hits	5
SwissProt Accessions	Q96JQ2, Q9H713, Q9HA23, Q9HA57, Q9UFP4, Q9ULN2	Gene names	CLMN, KIAA1188
Domain Architecture
Description	Calmin.

CLMN_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.068147 (rank : 68)
Query Neighborhood Hits	114	Target Neighborhood Hits	180	Shared Neighborhood Hits	10
SwissProt Accessions	Q8C5W0, Q91V71, Q91XT7, Q91XT8, Q91XU9	Gene names	Clmn
Domain Architecture
Description	Calmin.

CNOT3_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.060663 (rank : 88)
Query Neighborhood Hits	114	Target Neighborhood Hits	425	Shared Neighborhood Hits	41
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CNOT3_MOUSE
θ value	θ > 10 (rank : 137)	NC score	0.058099 (rank : 93)
Query Neighborhood Hits	114	Target Neighborhood Hits	504	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

DESP_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.079046 (rank : 38)
Query Neighborhood Hits	114	Target Neighborhood Hits	1470	Shared Neighborhood Hits	23
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

DMD_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.077875 (rank : 42)
Query Neighborhood Hits	114	Target Neighborhood Hits	1135	Shared Neighborhood Hits	13
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

DMD_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.079404 (rank : 37)
Query Neighborhood Hits	114	Target Neighborhood Hits	1111	Shared Neighborhood Hits	16
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

DRP2_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.066074 (rank : 72)
Query Neighborhood Hits	114	Target Neighborhood Hits	186	Shared Neighborhood Hits	7
SwissProt Accessions	Q13474	Gene names	DRP2
Domain Architecture
Description	Dystrophin-related protein 2.

EVPL_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.067504 (rank : 69)
Query Neighborhood Hits	114	Target Neighborhood Hits	895	Shared Neighborhood Hits	17
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

EVPL_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.071405 (rank : 61)
Query Neighborhood Hits	114	Target Neighborhood Hits	952	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

GOGB1_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.053068 (rank : 108)
Query Neighborhood Hits	114	Target Neighborhood Hits	2297	Shared Neighborhood Hits	31
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

GRIN1_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.055683 (rank : 100)
Query Neighborhood Hits	114	Target Neighborhood Hits	337	Shared Neighborhood Hits	31
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

GSCR1_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.061084 (rank : 85)
Query Neighborhood Hits	114	Target Neighborhood Hits	674	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

HMGA1_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.052008 (rank : 115)
Query Neighborhood Hits	114	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	P17096, P10910, Q9UKB0	Gene names	HMGA1, HMGIY
Domain Architecture	No domain graphic available
Description	High mobility group protein HMG-I/HMG-Y (HMG-I(Y)) (High mobility group AT-hook protein 1) (High mobility group protein A1) (High mobility group protein-R).

IQGA2_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.053285 (rank : 107)
Query Neighborhood Hits	114	Target Neighborhood Hits	200	Shared Neighborhood Hits	8
SwissProt Accessions	Q13576	Gene names	IQGAP2
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP2.

MBD6_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.075321 (rank : 49)
Query Neighborhood Hits	114	Target Neighborhood Hits	349	Shared Neighborhood Hits	34
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MILK1_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.076245 (rank : 46)
Query Neighborhood Hits	114	Target Neighborhood Hits	427	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MILK2_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.068432 (rank : 67)
Query Neighborhood Hits	114	Target Neighborhood Hits	457	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

MRIP_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.056092 (rank : 99)
Query Neighborhood Hits	114	Target Neighborhood Hits	578	Shared Neighborhood Hits	20
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

MRIP_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.050460 (rank : 124)
Query Neighborhood Hits	114	Target Neighborhood Hits	569	Shared Neighborhood Hits	16
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

MUC1_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.050290 (rank : 126)
Query Neighborhood Hits	114	Target Neighborhood Hits	975	Shared Neighborhood Hits	45
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MUC7_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.064876 (rank : 75)
Query Neighborhood Hits	114	Target Neighborhood Hits	538	Shared Neighborhood Hits	36
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NCOR2_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.054746 (rank : 103)
Query Neighborhood Hits	114	Target Neighborhood Hits	870	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NOLC1_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.066888 (rank : 71)
Query Neighborhood Hits	114	Target Neighborhood Hits	452	Shared Neighborhood Hits	31
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

PEPL_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.070563 (rank : 65)
Query Neighborhood Hits	114	Target Neighborhood Hits	1141	Shared Neighborhood Hits	17
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

PEPL_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.074559 (rank : 50)
Query Neighborhood Hits	114	Target Neighborhood Hits	1105	Shared Neighborhood Hits	19
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

PLEC1_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.094629 (rank : 23)
Query Neighborhood Hits	114	Target Neighborhood Hits	1326	Shared Neighborhood Hits	24
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

PPRB_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.052453 (rank : 112)
Query Neighborhood Hits	114	Target Neighborhood Hits	311	Shared Neighborhood Hits	28
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

PRB3_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.089962 (rank : 28)
Query Neighborhood Hits	114	Target Neighborhood Hits	318	Shared Neighborhood Hits	35
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.094798 (rank : 22)
Query Neighborhood Hits	114	Target Neighborhood Hits	330	Shared Neighborhood Hits	37
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRG4_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.073648 (rank : 56)
Query Neighborhood Hits	114	Target Neighborhood Hits	764	Shared Neighborhood Hits	48
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRG4_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.075446 (rank : 48)
Query Neighborhood Hits	114	Target Neighborhood Hits	624	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRP1_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.085210 (rank : 30)
Query Neighborhood Hits	114	Target Neighborhood Hits	385	Shared Neighborhood Hits	41
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.078919 (rank : 39)
Query Neighborhood Hits	114	Target Neighborhood Hits	347	Shared Neighborhood Hits	36
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRPC_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.059254 (rank : 92)
Query Neighborhood Hits	114	Target Neighborhood Hits	165	Shared Neighborhood Hits	19
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

PRR12_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.074470 (rank : 51)
Query Neighborhood Hits	114	Target Neighborhood Hits	460	Shared Neighborhood Hits	40
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

SFR17_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.053873 (rank : 104)
Query Neighborhood Hits	114	Target Neighborhood Hits	325	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

SMOO_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.087625 (rank : 29)
Query Neighborhood Hits	114	Target Neighborhood Hits	391	Shared Neighborhood Hits	36
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

SPTA1_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.074393 (rank : 52)
Query Neighborhood Hits	114	Target Neighborhood Hits	748	Shared Neighborhood Hits	15
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SPTA1_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.080623 (rank : 34)
Query Neighborhood Hits	114	Target Neighborhood Hits	675	Shared Neighborhood Hits	16
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SPTA2_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.080603 (rank : 35)
Query Neighborhood Hits	114	Target Neighborhood Hits	888	Shared Neighborhood Hits	17
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

SPTB1_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.073078 (rank : 60)
Query Neighborhood Hits	114	Target Neighborhood Hits	541	Shared Neighborhood Hits	11
SwissProt Accessions	P11277, Q15510, Q15519	Gene names	SPTB, SPTB1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

SPTB1_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.074344 (rank : 53)
Query Neighborhood Hits	114	Target Neighborhood Hits	543	Shared Neighborhood Hits	15
SwissProt Accessions	P15508	Gene names	Sptb, Spnb-1, Spnb1, Sptb1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

SPTB2_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.071234 (rank : 62)
Query Neighborhood Hits	114	Target Neighborhood Hits	748	Shared Neighborhood Hits	17
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTB2_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.069922 (rank : 66)
Query Neighborhood Hits	114	Target Neighborhood Hits	770	Shared Neighborhood Hits	15
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTN2_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.078149 (rank : 41)
Query Neighborhood Hits	114	Target Neighborhood Hits	535	Shared Neighborhood Hits	18
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

SPTN4_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.077057 (rank : 44)
Query Neighborhood Hits	114	Target Neighborhood Hits	570	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

SPTN5_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.077201 (rank : 43)
Query Neighborhood Hits	114	Target Neighborhood Hits	674	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

SRRM1_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.100941 (rank : 20)
Query Neighborhood Hits	114	Target Neighborhood Hits	690	Shared Neighborhood Hits	51
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.107577 (rank : 15)
Query Neighborhood Hits	114	Target Neighborhood Hits	966	Shared Neighborhood Hits	58
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM2_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.103499 (rank : 19)
Query Neighborhood Hits	114	Target Neighborhood Hits	1296	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SYN1_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.059333 (rank : 91)
Query Neighborhood Hits	114	Target Neighborhood Hits	419	Shared Neighborhood Hits	49
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

SYN1_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.052860 (rank : 109)
Query Neighborhood Hits	114	Target Neighborhood Hits	363	Shared Neighborhood Hits	41
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

SYNE1_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.080900 (rank : 33)
Query Neighborhood Hits	114	Target Neighborhood Hits	1484	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

SYNE2_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.070605 (rank : 64)
Query Neighborhood Hits	114	Target Neighborhood Hits	1323	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

TCOF_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.051919 (rank : 116)
Query Neighborhood Hits	114	Target Neighborhood Hits	543	Shared Neighborhood Hits	35
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TCOF_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.064456 (rank : 77)
Query Neighborhood Hits	114	Target Neighborhood Hits	471	Shared Neighborhood Hits	43
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TGON2_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.051415 (rank : 117)
Query Neighborhood Hits	114	Target Neighborhood Hits	1037	Shared Neighborhood Hits	47
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TRDN_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.050639 (rank : 121)
Query Neighborhood Hits	114	Target Neighborhood Hits	542	Shared Neighborhood Hits	23
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

UTRO_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.082207 (rank : 32)
Query Neighborhood Hits	114	Target Neighborhood Hits	960	Shared Neighborhood Hits	21
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

WASIP_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.073472 (rank : 58)
Query Neighborhood Hits	114	Target Neighborhood Hits	458	Shared Neighborhood Hits	42
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WASIP_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.070934 (rank : 63)
Query Neighborhood Hits	114	Target Neighborhood Hits	392	Shared Neighborhood Hits	39
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

WIRE_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.050990 (rank : 119)
Query Neighborhood Hits	114	Target Neighborhood Hits	329	Shared Neighborhood Hits	30
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

WIRE_MOUSE
θ value	θ > 10 (rank : 197)	NC score	0.053769 (rank : 105)
Query Neighborhood Hits	114	Target Neighborhood Hits	310	Shared Neighborhood Hits	32
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

YLPM1_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.050345 (rank : 125)
Query Neighborhood Hits	114	Target Neighborhood Hits	670	Shared Neighborhood Hits	42
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

Hits sorted by NC score

GA2L1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	114	Target Neighborhood Hits	114	Shared Neighborhood Hits	114
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

GA2L1_HUMAN
NC score	0.953169 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	114	Target Neighborhood Hits	177	Shared Neighborhood Hits	55
SwissProt Accessions	Q99501, Q53EN7, Q92640, Q9BUY9	Gene names	GAS2L1, GAR22
Domain Architecture
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1) (GAS2-related protein on chromosome 22) (GAR22 protein).

GA2L2_HUMAN
NC score	0.876083 (rank : 3)	θ value	5.17823e-64 (rank : 4)
Query Neighborhood Hits	114	Target Neighborhood Hits	175	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NHY3, Q8NHY4	Gene names	GAS2L2, GAR17
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2) (GAS2-related protein on chromosome 17) (GAR17 protein).

GAS2_MOUSE
NC score	0.832377 (rank : 4)	θ value	6.82597e-32 (rank : 6)
Query Neighborhood Hits	114	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	P11862	Gene names	Gas2, Gas-2
Domain Architecture
Description	Growth-arrest-specific protein 2 (GAS-2).

GAS2_HUMAN
NC score	0.832105 (rank : 5)	θ value	8.06329e-33 (rank : 5)
Query Neighborhood Hits	114	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	O43903, Q6ICV8	Gene names	GAS2
Domain Architecture
Description	Growth-arrest-specific protein 2 (GAS-2).

GA2L2_MOUSE
NC score	0.817501 (rank : 6)	θ value	1.66191e-70 (rank : 3)
Query Neighborhood Hits	114	Target Neighborhood Hits	395	Shared Neighborhood Hits	43
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

GA2L3_HUMAN
NC score	0.772752 (rank : 7)	θ value	1.28732e-30 (rank : 7)
Query Neighborhood Hits	114	Target Neighborhood Hits	189	Shared Neighborhood Hits	29
SwissProt Accessions	Q86XJ1	Gene names	GAS2L3
Domain Architecture	No domain graphic available
Description	GAS2-like protein 3 (Growth arrest-specific 2-like 3).

MACF4_HUMAN
NC score	0.267491 (rank : 8)	θ value	4.59992e-12 (rank : 10)
Query Neighborhood Hits	114	Target Neighborhood Hits	1321	Shared Neighborhood Hits	32
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

BPAEA_HUMAN
NC score	0.256536 (rank : 9)	θ value	6.00763e-12 (rank : 11)
Query Neighborhood Hits	114	Target Neighborhood Hits	1369	Shared Neighborhood Hits	30
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

MACF1_HUMAN
NC score	0.248424 (rank : 10)	θ value	4.91457e-14 (rank : 8)
Query Neighborhood Hits	114	Target Neighborhood Hits	1341	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF1_MOUSE
NC score	0.243034 (rank : 11)	θ value	4.59992e-12 (rank : 9)
Query Neighborhood Hits	114	Target Neighborhood Hits	1313	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

BPA1_MOUSE
NC score	0.224243 (rank : 12)	θ value	2.28291e-11 (rank : 12)
Query Neighborhood Hits	114	Target Neighborhood Hits	1477	Shared Neighborhood Hits	35
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

TARA_HUMAN
NC score	0.126456 (rank : 13)	θ value	3.19293e-05 (rank : 13)
Query Neighborhood Hits	114	Target Neighborhood Hits	1626	Shared Neighborhood Hits	55
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SRRM2_MOUSE
NC score	0.118830 (rank : 14)	θ value	0.0330416 (rank : 21)
Query Neighborhood Hits	114	Target Neighborhood Hits	1470	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SRRM1_MOUSE
NC score	0.107577 (rank : 15)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	114	Target Neighborhood Hits	966	Shared Neighborhood Hits	58
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

BAT2_HUMAN
NC score	0.104982 (rank : 16)	θ value	0.47712 (rank : 37)
Query Neighborhood Hits	114	Target Neighborhood Hits	931	Shared Neighborhood Hits	58
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BPAEA_MOUSE
NC score	0.104658 (rank : 17)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	114	Target Neighborhood Hits	1480	Shared Neighborhood Hits	24
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

TARA_MOUSE
NC score	0.103633 (rank : 18)	θ value	0.0563607 (rank : 24)
Query Neighborhood Hits	114	Target Neighborhood Hits	1133	Shared Neighborhood Hits	52
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SRRM2_HUMAN
NC score	0.103499 (rank : 19)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	114	Target Neighborhood Hits	1296	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM1_HUMAN
NC score	0.100941 (rank : 20)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	114	Target Neighborhood Hits	690	Shared Neighborhood Hits	51
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

BAT2_MOUSE
NC score	0.099824 (rank : 21)	θ value	0.0563607 (rank : 22)
Query Neighborhood Hits	114	Target Neighborhood Hits	947	Shared Neighborhood Hits	49
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

PRB4S_HUMAN
NC score	0.094798 (rank : 22)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	114	Target Neighborhood Hits	330	Shared Neighborhood Hits	37
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PLEC1_HUMAN
NC score	0.094629 (rank : 23)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	114	Target Neighborhood Hits	1326	Shared Neighborhood Hits	24
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

MDC1_HUMAN
NC score	0.093185 (rank : 24)	θ value	0.125558 (rank : 28)
Query Neighborhood Hits	114	Target Neighborhood Hits	1446	Shared Neighborhood Hits	61
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

KI67_HUMAN
NC score	0.092589 (rank : 25)	θ value	0.00665767 (rank : 17)
Query Neighborhood Hits	114	Target Neighborhood Hits	581	Shared Neighborhood Hits	28
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

TSNA1_HUMAN
NC score	0.091984 (rank : 26)	θ value	0.00175202 (rank : 14)
Query Neighborhood Hits	114	Target Neighborhood Hits	178	Shared Neighborhood Hits	11
SwissProt Accessions	Q96NA8	Gene names	TSNARE1
Domain Architecture	No domain graphic available
Description	t-SNARE domain-containing protein 1.

MDC1_MOUSE
NC score	0.090377 (rank : 27)	θ value	0.0736092 (rank : 25)
Query Neighborhood Hits	114	Target Neighborhood Hits	998	Shared Neighborhood Hits	51
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

PRB3_HUMAN
NC score	0.089962 (rank : 28)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	114	Target Neighborhood Hits	318	Shared Neighborhood Hits	35
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

SMOO_HUMAN
NC score	0.087625 (rank : 29)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	114	Target Neighborhood Hits	391	Shared Neighborhood Hits	36
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

PRP1_HUMAN
NC score	0.085210 (rank : 30)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	114	Target Neighborhood Hits	385	Shared Neighborhood Hits	41
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

MILK1_MOUSE
NC score	0.084143 (rank : 31)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	114	Target Neighborhood Hits	788	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

UTRO_HUMAN
NC score	0.082207 (rank : 32)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	114	Target Neighborhood Hits	960	Shared Neighborhood Hits	21
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

SYNE1_HUMAN
NC score	0.080900 (rank : 33)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	114	Target Neighborhood Hits	1484	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

SPTA1_MOUSE
NC score	0.080623 (rank : 34)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	114	Target Neighborhood Hits	675	Shared Neighborhood Hits	16
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SPTA2_HUMAN
NC score	0.080603 (rank : 35)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	114	Target Neighborhood Hits	888	Shared Neighborhood Hits	17
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

GRIN1_HUMAN
NC score	0.080053 (rank : 36)	θ value	0.47712 (rank : 39)
Query Neighborhood Hits	114	Target Neighborhood Hits	681	Shared Neighborhood Hits	48
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

DMD_MOUSE
NC score	0.079404 (rank : 37)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	114	Target Neighborhood Hits	1111	Shared Neighborhood Hits	16
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

DESP_HUMAN
NC score	0.079046 (rank : 38)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	114	Target Neighborhood Hits	1470	Shared Neighborhood Hits	23
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

PRP2_MOUSE
NC score	0.078919 (rank : 39)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	114	Target Neighborhood Hits	347	Shared Neighborhood Hits	36
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

TGON1_MOUSE
NC score	0.078850 (rank : 40)	θ value	0.21417 (rank : 31)
Query Neighborhood Hits	114	Target Neighborhood Hits	243	Shared Neighborhood Hits	20
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

SPTN2_HUMAN
NC score	0.078149 (rank : 41)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	114	Target Neighborhood Hits	535	Shared Neighborhood Hits	18
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

DMD_HUMAN
NC score	0.077875 (rank : 42)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	114	Target Neighborhood Hits	1135	Shared Neighborhood Hits	13
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

SPTN5_HUMAN
NC score	0.077201 (rank : 43)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	114	Target Neighborhood Hits	674	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

SPTN4_HUMAN
NC score	0.077057 (rank : 44)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	114	Target Neighborhood Hits	570	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

IQGA1_MOUSE
NC score	0.076436 (rank : 45)	θ value	0.279714 (rank : 33)
Query Neighborhood Hits	114	Target Neighborhood Hits	219	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JKF1	Gene names	Iqgap1
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1.

MILK1_HUMAN
NC score	0.076245 (rank : 46)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	114	Target Neighborhood Hits	427	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

DOT1L_HUMAN
NC score	0.075909 (rank : 47)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	114	Target Neighborhood Hits	660	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

PRG4_MOUSE
NC score	0.075446 (rank : 48)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	114	Target Neighborhood Hits	624	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

MBD6_HUMAN
NC score	0.075321 (rank : 49)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	114	Target Neighborhood Hits	349	Shared Neighborhood Hits	34
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

PEPL_MOUSE
NC score	0.074559 (rank : 50)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	114	Target Neighborhood Hits	1105	Shared Neighborhood Hits	19
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

PRR12_HUMAN
NC score	0.074470 (rank : 51)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	114	Target Neighborhood Hits	460	Shared Neighborhood Hits	40
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

SPTA1_HUMAN
NC score	0.074393 (rank : 52)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	114	Target Neighborhood Hits	748	Shared Neighborhood Hits	15
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SPTB1_MOUSE
NC score	0.074344 (rank : 53)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	114	Target Neighborhood Hits	543	Shared Neighborhood Hits	15
SwissProt Accessions	P15508	Gene names	Sptb, Spnb-1, Spnb1, Sptb1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

IQGA1_HUMAN
NC score	0.073768 (rank : 54)	θ value	0.279714 (rank : 32)
Query Neighborhood Hits	114	Target Neighborhood Hits	250	Shared Neighborhood Hits	13
SwissProt Accessions	P46940	Gene names	IQGAP1, KIAA0051
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1 (p195).

NACAM_MOUSE
NC score	0.073710 (rank : 55)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	114	Target Neighborhood Hits	1866	Shared Neighborhood Hits	70
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PRG4_HUMAN
NC score	0.073648 (rank : 56)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	114	Target Neighborhood Hits	764	Shared Neighborhood Hits	48
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

BAG3_MOUSE
NC score	0.073561 (rank : 57)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	114	Target Neighborhood Hits	513	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

WASIP_HUMAN
NC score	0.073472 (rank : 58)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	114	Target Neighborhood Hits	458	Shared Neighborhood Hits	42
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

TGON2_MOUSE
NC score	0.073267 (rank : 59)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	114	Target Neighborhood Hits	277	Shared Neighborhood Hits	24
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

SPTB1_HUMAN
NC score	0.073078 (rank : 60)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	114	Target Neighborhood Hits	541	Shared Neighborhood Hits	11
SwissProt Accessions	P11277, Q15510, Q15519	Gene names	SPTB, SPTB1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

EVPL_MOUSE
NC score	0.071405 (rank : 61)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	114	Target Neighborhood Hits	952	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

SPTB2_HUMAN
NC score	0.071234 (rank : 62)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	114	Target Neighborhood Hits	748	Shared Neighborhood Hits	17
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

WASIP_MOUSE
NC score	0.070934 (rank : 63)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	114	Target Neighborhood Hits	392	Shared Neighborhood Hits	39
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

SYNE2_HUMAN
NC score	0.070605 (rank : 64)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	114	Target Neighborhood Hits	1323	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

PEPL_HUMAN
NC score	0.070563 (rank : 65)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	114	Target Neighborhood Hits	1141	Shared Neighborhood Hits	17
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

SPTB2_MOUSE
NC score	0.069922 (rank : 66)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	114	Target Neighborhood Hits	770	Shared Neighborhood Hits	15
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

MILK2_HUMAN
NC score	0.068432 (rank : 67)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	114	Target Neighborhood Hits	457	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

CLMN_MOUSE
NC score	0.068147 (rank : 68)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	114	Target Neighborhood Hits	180	Shared Neighborhood Hits	10
SwissProt Accessions	Q8C5W0, Q91V71, Q91XT7, Q91XT8, Q91XU9	Gene names	Clmn
Domain Architecture
Description	Calmin.

EVPL_HUMAN
NC score	0.067504 (rank : 69)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	114	Target Neighborhood Hits	895	Shared Neighborhood Hits	17
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

IASPP_MOUSE
NC score	0.067071 (rank : 70)	θ value	0.0148317 (rank : 19)
Query Neighborhood Hits	114	Target Neighborhood Hits	1024	Shared Neighborhood Hits	40
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

NOLC1_HUMAN
NC score	0.066888 (rank : 71)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	114	Target Neighborhood Hits	452	Shared Neighborhood Hits	31
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

DRP2_HUMAN
NC score	0.066074 (rank : 72)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	114	Target Neighborhood Hits	186	Shared Neighborhood Hits	7
SwissProt Accessions	Q13474	Gene names	DRP2
Domain Architecture
Description	Dystrophin-related protein 2.

AKAP6_HUMAN
NC score	0.065973 (rank : 73)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	114	Target Neighborhood Hits	263	Shared Neighborhood Hits	12
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

CLMN_HUMAN
NC score	0.065034 (rank : 74)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	114	Target Neighborhood Hits	205	Shared Neighborhood Hits	5
SwissProt Accessions	Q96JQ2, Q9H713, Q9HA23, Q9HA57, Q9UFP4, Q9ULN2	Gene names	CLMN, KIAA1188
Domain Architecture
Description	Calmin.

MUC7_HUMAN
NC score	0.064876 (rank : 75)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	114	Target Neighborhood Hits	538	Shared Neighborhood Hits	36
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NPBL_MOUSE
NC score	0.064798 (rank : 76)	θ value	0.47712 (rank : 40)
Query Neighborhood Hits	114	Target Neighborhood Hits	1041	Shared Neighborhood Hits	39
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

TCOF_MOUSE
NC score	0.064456 (rank : 77)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	114	Target Neighborhood Hits	471	Shared Neighborhood Hits	43
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

ACTN3_MOUSE
NC score	0.063438 (rank : 78)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	114	Target Neighborhood Hits	265	Shared Neighborhood Hits	9
SwissProt Accessions	O88990	Gene names	Actn3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

ACTN1_MOUSE
NC score	0.062638 (rank : 79)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	114	Target Neighborhood Hits	216	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TPR4	Gene names	Actn1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

ACTN1_HUMAN
NC score	0.062179 (rank : 80)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	114	Target Neighborhood Hits	221	Shared Neighborhood Hits	7
SwissProt Accessions	P12814, Q9BTN1	Gene names	ACTN1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

ACTN4_MOUSE
NC score	0.062065 (rank : 81)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	114	Target Neighborhood Hits	276	Shared Neighborhood Hits	7
SwissProt Accessions	P57780	Gene names	Actn4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

ACTN2_MOUSE
NC score	0.061941 (rank : 82)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	114	Target Neighborhood Hits	287	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JI91	Gene names	Actn2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

NIPBL_HUMAN
NC score	0.061797 (rank : 83)	θ value	0.125558 (rank : 29)
Query Neighborhood Hits	114	Target Neighborhood Hits	1311	Shared Neighborhood Hits	39
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

ACTN4_HUMAN
NC score	0.061523 (rank : 84)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	114	Target Neighborhood Hits	279	Shared Neighborhood Hits	8
SwissProt Accessions	O43707, O76048	Gene names	ACTN4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

GSCR1_HUMAN
NC score	0.061084 (rank : 85)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	114	Target Neighborhood Hits	674	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

BASP_MOUSE
NC score	0.060880 (rank : 86)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	114	Target Neighborhood Hits	260	Shared Neighborhood Hits	28
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

ACTN3_HUMAN
NC score	0.060672 (rank : 87)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	114	Target Neighborhood Hits	272	Shared Neighborhood Hits	7
SwissProt Accessions	Q08043	Gene names	ACTN3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

CNOT3_HUMAN
NC score	0.060663 (rank : 88)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	114	Target Neighborhood Hits	425	Shared Neighborhood Hits	41
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

ACTN2_HUMAN
NC score	0.060320 (rank : 89)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	114	Target Neighborhood Hits	295	Shared Neighborhood Hits	7
SwissProt Accessions	P35609, Q86TF4, Q86TI8	Gene names	ACTN2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

CRTC1_HUMAN
NC score	0.059601 (rank : 90)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	114	Target Neighborhood Hits	319	Shared Neighborhood Hits	26
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

SYN1_HUMAN
NC score	0.059333 (rank : 91)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	114	Target Neighborhood Hits	419	Shared Neighborhood Hits	49
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

PRPC_HUMAN
NC score	0.059254 (rank : 92)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	114	Target Neighborhood Hits	165	Shared Neighborhood Hits	19
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

CNOT3_MOUSE
NC score	0.058099 (rank : 93)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	114	Target Neighborhood Hits	504	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

MAGE1_HUMAN
NC score	0.058064 (rank : 94)	θ value	0.00390308 (rank : 16)
Query Neighborhood Hits	114	Target Neighborhood Hits	1389	Shared Neighborhood Hits	57
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

TTC16_HUMAN
NC score	0.058031 (rank : 95)	θ value	0.813845 (rank : 44)
Query Neighborhood Hits	114	Target Neighborhood Hits	417	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

NU214_HUMAN
NC score	0.057790 (rank : 96)	θ value	1.38821 (rank : 51)
Query Neighborhood Hits	114	Target Neighborhood Hits	657	Shared Neighborhood Hits	39
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

SFRIP_HUMAN
NC score	0.056952 (rank : 97)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	114	Target Neighborhood Hits	530	Shared Neighborhood Hits	29
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

BSN_MOUSE
NC score	0.056547 (rank : 98)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	114	Target Neighborhood Hits	2057	Shared Neighborhood Hits	74
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

MRIP_HUMAN
NC score	0.056092 (rank : 99)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	114	Target Neighborhood Hits	578	Shared Neighborhood Hits	20
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

GRIN1_MOUSE
NC score	0.055683 (rank : 100)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	114	Target Neighborhood Hits	337	Shared Neighborhood Hits	31
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

BAG3_HUMAN
NC score	0.055673 (rank : 101)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	114	Target Neighborhood Hits	314	Shared Neighborhood Hits	33
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

BASP_HUMAN
NC score	0.055621 (rank : 102)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	114	Target Neighborhood Hits	321	Shared Neighborhood Hits	28
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

NCOR2_HUMAN
NC score	0.054746 (rank : 103)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	114	Target Neighborhood Hits	870	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

SFR17_HUMAN
NC score	0.053873 (rank : 104)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	114	Target Neighborhood Hits	325	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

WIRE_MOUSE
NC score	0.053769 (rank : 105)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	114	Target Neighborhood Hits	310	Shared Neighborhood Hits	32
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

PRRT3_HUMAN
NC score	0.053364 (rank : 106)	θ value	0.813845 (rank : 42)
Query Neighborhood Hits	114	Target Neighborhood Hits	998	Shared Neighborhood Hits	46
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

IQGA2_HUMAN
NC score	0.053285 (rank : 107)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	114	Target Neighborhood Hits	200	Shared Neighborhood Hits	8
SwissProt Accessions	Q13576	Gene names	IQGAP2
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP2.

GOGB1_HUMAN
NC score	0.053068 (rank : 108)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	114	Target Neighborhood Hits	2297	Shared Neighborhood Hits	31
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

SYN1_MOUSE
NC score	0.052860 (rank : 109)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	114	Target Neighborhood Hits	363	Shared Neighborhood Hits	41
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

CK024_HUMAN
NC score	0.052838 (rank : 110)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	114	Target Neighborhood Hits	408	Shared Neighborhood Hits	31
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

OGFR_HUMAN
NC score	0.052621 (rank : 111)	θ value	0.365318 (rank : 35)
Query Neighborhood Hits	114	Target Neighborhood Hits	1582	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PPRB_HUMAN
NC score	0.052453 (rank : 112)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	114	Target Neighborhood Hits	311	Shared Neighborhood Hits	28
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

CRTC1_MOUSE
NC score	0.052350 (rank : 113)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	114	Target Neighborhood Hits	230	Shared Neighborhood Hits	18
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

CAYP1_HUMAN
NC score	0.052176 (rank : 114)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	114	Target Neighborhood Hits	94	Shared Neighborhood Hits	5
SwissProt Accessions	Q13938, Q3MJA7, Q8WUZ3	Gene names	CAPS
Domain Architecture
Description	Calcyphosin (Calcyphosine).

HMGA1_HUMAN
NC score	0.052008 (rank : 115)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	114	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	P17096, P10910, Q9UKB0	Gene names	HMGA1, HMGIY
Domain Architecture	No domain graphic available
Description	High mobility group protein HMG-I/HMG-Y (HMG-I(Y)) (High mobility group AT-hook protein 1) (High mobility group protein A1) (High mobility group protein-R).

TCOF_HUMAN
NC score	0.051919 (rank : 116)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	114	Target Neighborhood Hits	543	Shared Neighborhood Hits	35
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TGON2_HUMAN
NC score	0.051415 (rank : 117)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	114	Target Neighborhood Hits	1037	Shared Neighborhood Hits	47
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

ATN1_HUMAN
NC score	0.051342 (rank : 118)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	114	Target Neighborhood Hits	676	Shared Neighborhood Hits	37
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

WIRE_HUMAN
NC score	0.050990 (rank : 119)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	114	Target Neighborhood Hits	329	Shared Neighborhood Hits	30
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

ANK2_HUMAN
NC score	0.050800 (rank : 120)	θ value	0.0330416 (rank : 20)
Query Neighborhood Hits	114	Target Neighborhood Hits	1615	Shared Neighborhood Hits	62
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

TRDN_HUMAN
NC score	0.050639 (rank : 121)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	114	Target Neighborhood Hits	542	Shared Neighborhood Hits	23
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TAU_MOUSE
NC score	0.050525 (rank : 122)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	114	Target Neighborhood Hits	502	Shared Neighborhood Hits	38
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

CJ078_MOUSE
NC score	0.050461 (rank : 123)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	114	Target Neighborhood Hits	559	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

MRIP_MOUSE
NC score	0.050460 (rank : 124)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	114	Target Neighborhood Hits	569	Shared Neighborhood Hits	16
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

YLPM1_HUMAN
NC score	0.050345 (rank : 125)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	114	Target Neighborhood Hits	670	Shared Neighborhood Hits	42
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

MUC1_HUMAN
NC score	0.050290 (rank : 126)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	114	Target Neighborhood Hits	975	Shared Neighborhood Hits	45
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

ALEX_HUMAN
NC score	0.050090 (rank : 127)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	114	Target Neighborhood Hits	361	Shared Neighborhood Hits	29
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

CA147_HUMAN
NC score	0.047400 (rank : 128)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	114	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q96MC9, Q5JTS5	Gene names	C1orf147
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf147.

GOGA3_HUMAN
NC score	0.044957 (rank : 129)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	114	Target Neighborhood Hits	1317	Shared Neighborhood Hits	29
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

APXL_HUMAN
NC score	0.044389 (rank : 130)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	114	Target Neighborhood Hits	553	Shared Neighborhood Hits	37
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

RGS3_MOUSE
NC score	0.043561 (rank : 131)	θ value	0.279714 (rank : 34)
Query Neighborhood Hits	114	Target Neighborhood Hits	1621	Shared Neighborhood Hits	60
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

CNN3_MOUSE
NC score	0.042435 (rank : 132)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	114	Target Neighborhood Hits	45	Shared Neighborhood Hits	8
SwissProt Accessions	Q9DAW9, Q3TW23	Gene names	Cnn3
Domain Architecture	No domain graphic available
Description	Calponin-3 (Calponin, acidic isoform).

CSF1_HUMAN
NC score	0.041361 (rank : 133)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	114	Target Neighborhood Hits	258	Shared Neighborhood Hits	27
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

TXLNB_HUMAN
NC score	0.040590 (rank : 134)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	114	Target Neighborhood Hits	912	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

AMOT_HUMAN
NC score	0.039971 (rank : 135)	θ value	1.06291 (rank : 45)
Query Neighborhood Hits	114	Target Neighborhood Hits	712	Shared Neighborhood Hits	26
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

HRX_HUMAN
NC score	0.038786 (rank : 136)	θ value	1.06291 (rank : 47)
Query Neighborhood Hits	114	Target Neighborhood Hits	825	Shared Neighborhood Hits	39
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

K1802_MOUSE
NC score	0.038521 (rank : 137)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	114	Target Neighborhood Hits	1596	Shared Neighborhood Hits	51
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

CO5A1_MOUSE
NC score	0.036618 (rank : 138)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	114	Target Neighborhood Hits	419	Shared Neighborhood Hits	36
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

CTG1B_HUMAN
NC score	0.036083 (rank : 139)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	114	Target Neighborhood Hits	61	Shared Neighborhood Hits	7
SwissProt Accessions	P78358, Q7LBY4	Gene names	CTAG1B, CTAG, CTAG1, ESO1, LAGE2
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen 1B (L antigen family member 2) (LAGE-2 protein) (Autoimmunogenic cancer/testis antigen NY-ESO-1).

CO5A2_HUMAN
NC score	0.036045 (rank : 140)	θ value	0.0563607 (rank : 23)
Query Neighborhood Hits	114	Target Neighborhood Hits	760	Shared Neighborhood Hits	34
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

CSKI1_HUMAN
NC score	0.035975 (rank : 141)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	114	Target Neighborhood Hits	997	Shared Neighborhood Hits	52
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

BCOR_HUMAN
NC score	0.035469 (rank : 142)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	114	Target Neighborhood Hits	609	Shared Neighborhood Hits	20
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CAC1A_HUMAN
NC score	0.035081 (rank : 143)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	114	Target Neighborhood Hits	387	Shared Neighborhood Hits	36
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

BCOR_MOUSE
NC score	0.034524 (rank : 144)	θ value	0.47712 (rank : 38)
Query Neighborhood Hits	114	Target Neighborhood Hits	521	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

SHAN1_HUMAN
NC score	0.033932 (rank : 145)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	114	Target Neighborhood Hits	1041	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

CECR2_HUMAN
NC score	0.033844 (rank : 146)	θ value	0.62314 (rank : 41)
Query Neighborhood Hits	114	Target Neighborhood Hits	543	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

CO5A1_HUMAN
NC score	0.033774 (rank : 147)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	114	Target Neighborhood Hits	434	Shared Neighborhood Hits	36
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

TENS1_HUMAN
NC score	0.033455 (rank : 148)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	114	Target Neighborhood Hits	400	Shared Neighborhood Hits	26
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

CSKI1_MOUSE
NC score	0.032830 (rank : 149)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	114	Target Neighborhood Hits	1031	Shared Neighborhood Hits	44
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

PDZD2_HUMAN
NC score	0.032583 (rank : 150)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	114	Target Neighborhood Hits	772	Shared Neighborhood Hits	38
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

CAC1H_HUMAN
NC score	0.030559 (rank : 151)	θ value	0.21417 (rank : 30)
Query Neighborhood Hits	114	Target Neighborhood Hits	307	Shared Neighborhood Hits	19
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CO9A2_HUMAN
NC score	0.030512 (rank : 152)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	114	Target Neighborhood Hits	261	Shared Neighborhood Hits	22
SwissProt Accessions	Q14055	Gene names	COL9A2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

CUTL2_HUMAN
NC score	0.029092 (rank : 153)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	114	Target Neighborhood Hits	906	Shared Neighborhood Hits	34
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

CTAG2_HUMAN
NC score	0.028769 (rank : 154)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	114	Target Neighborhood Hits	65	Shared Neighborhood Hits	8
SwissProt Accessions	O75638, O75637, Q9BU80, Q9UJ89, Q9Y479	Gene names	CTAG2, ESO2, LAGE1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen 2 (L antigen family member 1) (LAGE-1 protein) (ESO-2 protein).

CT2NL_MOUSE
NC score	0.028314 (rank : 155)	θ value	1.06291 (rank : 46)
Query Neighborhood Hits	114	Target Neighborhood Hits	902	Shared Neighborhood Hits	20
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

RUSC1_HUMAN
NC score	0.028182 (rank : 156)	θ value	1.06291 (rank : 48)
Query Neighborhood Hits	114	Target Neighborhood Hits	226	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

MAST4_HUMAN
NC score	0.027981 (rank : 157)	θ value	0.0113563 (rank : 18)
Query Neighborhood Hits	114	Target Neighborhood Hits	1804	Shared Neighborhood Hits	62
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

CAC1A_MOUSE
NC score	0.026935 (rank : 158)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	114	Target Neighborhood Hits	267	Shared Neighborhood Hits	26
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1H_MOUSE
NC score	0.026788 (rank : 159)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	114	Target Neighborhood Hits	230	Shared Neighborhood Hits	18
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

SPEG_MOUSE
NC score	0.025735 (rank : 160)	θ value	0.365318 (rank : 36)
Query Neighborhood Hits	114	Target Neighborhood Hits	1959	Shared Neighborhood Hits	54
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ICB1_MOUSE
NC score	0.024504 (rank : 161)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	114	Target Neighborhood Hits	69	Shared Neighborhood Hits	5
SwissProt Accessions	Q91YX0	Gene names	Icb1
Domain Architecture	No domain graphic available
Description	Induced by contact to basement membrane 1 protein homolog (ICB-1 protein).

SPEG_HUMAN
NC score	0.023765 (rank : 162)	θ value	0.813845 (rank : 43)
Query Neighborhood Hits	114	Target Neighborhood Hits	1762	Shared Neighborhood Hits	56
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

CAC1B_MOUSE
NC score	0.023689 (rank : 163)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	114	Target Neighborhood Hits	351	Shared Neighborhood Hits	28
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

FBX41_HUMAN
NC score	0.022725 (rank : 164)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	114	Target Neighborhood Hits	475	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TF61	Gene names	FBXO41, FBX41, KIAA1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

IL3B2_MOUSE
NC score	0.022699 (rank : 165)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	114	Target Neighborhood Hits	372	Shared Neighborhood Hits	18
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

FBX41_MOUSE
NC score	0.022539 (rank : 166)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	114	Target Neighborhood Hits	430	Shared Neighborhood Hits	15
SwissProt Accessions	Q6NS60, Q6P7W4, Q6ZPG1	Gene names	Fbxo41, D6Ertd538e, Kiaa1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

IF4G3_MOUSE
NC score	0.022311 (rank : 167)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	114	Target Neighborhood Hits	279	Shared Neighborhood Hits	14
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

CT128_HUMAN
NC score	0.021197 (rank : 168)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	114	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BQN1, Q5JWN6, Q8N276	Gene names	C20orf128
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf128.

PRGR_HUMAN
NC score	0.020715 (rank : 169)	θ value	0.0961366 (rank : 26)
Query Neighborhood Hits	114	Target Neighborhood Hits	163	Shared Neighborhood Hits	8
SwissProt Accessions	P06401, Q9UPF7	Gene names	PGR, NR3C3
Domain Architecture
Description	Progesterone receptor (PR).

TERF2_MOUSE
NC score	0.020062 (rank : 170)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	114	Target Neighborhood Hits	128	Shared Neighborhood Hits	11
SwissProt Accessions	O35144	Gene names	Terf2, Trf2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

HAIR_MOUSE
NC score	0.018303 (rank : 171)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	114	Target Neighborhood Hits	97	Shared Neighborhood Hits	5
SwissProt Accessions	Q61645, Q80Y47	Gene names	Hr
Domain Architecture
Description	Protein hairless.

CDKL5_HUMAN
NC score	0.017049 (rank : 172)	θ value	0.00298849 (rank : 15)
Query Neighborhood Hits	114	Target Neighborhood Hits	967	Shared Neighborhood Hits	19
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

CAMKV_HUMAN
NC score	0.016210 (rank : 173)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	114	Target Neighborhood Hits	1084	Shared Neighborhood Hits	35
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

CASP8_HUMAN
NC score	0.016129 (rank : 174)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	114	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q14790, O14676, Q14791, Q14792, Q14793, Q14794, Q14795, Q14796, Q15780, Q15806, Q53TT5, Q8TDI1, Q8TDI2, Q8TDI3, Q8TDI4, Q8TDI5, Q96T22, Q9C0K4, Q9UQ81	Gene names	CASP8, MCH5
Domain Architecture
Description	Caspase-8 precursor (EC 3.4.22.-) (CASP-8) (ICE-like apoptotic protease 5) (MORT1-associated CED-3 homolog) (MACH) (FADD-homologous ICE/CED-3-like protease) (FADD-like ICE) (FLICE) (Apoptotic cysteine protease) (Apoptotic protease Mch-5) (CAP4) [Contains: Caspase-8 subunit p18; Caspase-8 subunit p10].

DLG7_MOUSE
NC score	0.016079 (rank : 175)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	114	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K4R9, Q6ZQL3, Q80VS7, Q8BUC8, Q8BZ79	Gene names	Dlg7, Kiaa0008
Domain Architecture	No domain graphic available
Description	Discs large homolog 7 (Hepatoma up-regulated protein homolog) (HURP).

SREC_HUMAN
NC score	0.015134 (rank : 176)	θ value	0.0961366 (rank : 27)
Query Neighborhood Hits	114	Target Neighborhood Hits	645	Shared Neighborhood Hits	15
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

SMAL1_MOUSE
NC score	0.014873 (rank : 177)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	114	Target Neighborhood Hits	157	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

ES8L3_HUMAN
NC score	0.013770 (rank : 178)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	114	Target Neighborhood Hits	206	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

ARRD1_HUMAN
NC score	0.013193 (rank : 179)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	114	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N5I2	Gene names	ARRDC1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

RPGF6_HUMAN
NC score	0.013107 (rank : 180)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	114	Target Neighborhood Hits	266	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

CBL_HUMAN
NC score	0.012795 (rank : 181)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	114	Target Neighborhood Hits	353	Shared Neighborhood Hits	17
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

S45A3_MOUSE
NC score	0.012014 (rank : 182)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	114	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K0H7, Q8K252, Q8R1I0	Gene names	Slc45a3, Pcanap6, Prst
Domain Architecture	No domain graphic available
Description	Solute carrier family 45 member 3 (Prostate cancer-associated protein 6) (Prostein).

JIP3_HUMAN
NC score	0.011885 (rank : 183)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	114	Target Neighborhood Hits	1039	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

PAK4_MOUSE
NC score	0.010892 (rank : 184)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	114	Target Neighborhood Hits	1098	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

DEN2A_HUMAN
NC score	0.010712 (rank : 185)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	114	Target Neighborhood Hits	83	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ULE3, Q1RMD5, Q86XY0	Gene names	DENND2A, KIAA1277
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

ULK1_HUMAN
NC score	0.010245 (rank : 186)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	114	Target Neighborhood Hits	1121	Shared Neighborhood Hits	30
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

MARK2_MOUSE
NC score	0.010173 (rank : 187)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	114	Target Neighborhood Hits	1018	Shared Neighborhood Hits	22
SwissProt Accessions	Q05512, Q6PDR4, Q8BR95	Gene names	Mark2, Emk
Domain Architecture
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1).

NALP1_HUMAN
NC score	0.010104 (rank : 188)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	114	Target Neighborhood Hits	138	Shared Neighborhood Hits	9
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

C2TA_MOUSE
NC score	0.009886 (rank : 189)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	114	Target Neighborhood Hits	131	Shared Neighborhood Hits	5
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).

PP4R1_MOUSE
NC score	0.009783 (rank : 190)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	114	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K2V1, Q8R0R8	Gene names	Ppp4r1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

RARA_HUMAN
NC score	0.008809 (rank : 191)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	114	Target Neighborhood Hits	118	Shared Neighborhood Hits	5
SwissProt Accessions	P10276, P78456, Q13440, Q13441, Q9NQS0	Gene names	RARA, NR1B1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

PANK1_MOUSE
NC score	0.008707 (rank : 192)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	114	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K4K6, Q9D3K1, Q9QXM8	Gene names	Pank1, Pank
Domain Architecture
Description	Pantothenate kinase 1 (EC 2.7.1.33) (Pantothenic acid kinase 1) (mPank1) (mPank).

ULK1_MOUSE
NC score	0.008252 (rank : 193)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	114	Target Neighborhood Hits	1214	Shared Neighborhood Hits	27
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

M3K9_HUMAN
NC score	0.005561 (rank : 194)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	114	Target Neighborhood Hits	1123	Shared Neighborhood Hits	23
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

DCBD1_HUMAN
NC score	0.005370 (rank : 195)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	114	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DLX5_MOUSE
NC score	0.004420 (rank : 196)	θ value	3.0926 (rank : 63)
Query Neighborhood Hits	114	Target Neighborhood Hits	434	Shared Neighborhood Hits	8
SwissProt Accessions	P70396, O54876, O54877, O54878, Q9JJ45	Gene names	Dlx5
Domain Architecture
Description	Homeobox protein DLX-5.

ABL2_HUMAN
NC score	0.003871 (rank : 197)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	114	Target Neighborhood Hits	1045	Shared Neighborhood Hits	21
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

TCF8_MOUSE
NC score	-0.000751 (rank : 198)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	114	Target Neighborhood Hits	1067	Shared Neighborhood Hits	13
SwissProt Accessions	Q64318, Q62519	Gene names	Tcf8, Zfhx1a, Zfx1a, Zfx1ha
Domain Architecture
Description	Transcription factor 8 (Zinc finger homeobox protein 1a) (MEB1) (Delta EF1).