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Network neighborhood for query Sequence : TENS1_HUMAN

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TENS1_HUMAN
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TENS1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	400	Target Neighborhood Hits	400	Shared Neighborhood Hits	400
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

TENS4_HUMAN
θ value	4.21644e-82 (rank : 2)	NC score	0.625696 (rank : 3)
Query Neighborhood Hits	400	Target Neighborhood Hits	214	Shared Neighborhood Hits	76
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

TENS4_MOUSE
θ value	5.50685e-82 (rank : 3)	NC score	0.627888 (rank : 2)
Query Neighborhood Hits	400	Target Neighborhood Hits	225	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

GAK_MOUSE
θ value	1.73584e-35 (rank : 4)	NC score	0.236287 (rank : 10)
Query Neighborhood Hits	400	Target Neighborhood Hits	964	Shared Neighborhood Hits	69
SwissProt Accessions	Q99KY4, Q6P1I8, Q6P9S5, Q8BM74, Q8K0Q4	Gene names	Gak
Domain Architecture	No domain graphic available
Description	Cyclin G-associated kinase (EC 2.7.11.1).

GAK_HUMAN
θ value	1.9192e-34 (rank : 5)	NC score	0.233248 (rank : 11)
Query Neighborhood Hits	400	Target Neighborhood Hits	1028	Shared Neighborhood Hits	86
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

PTEN_HUMAN
θ value	9.52487e-34 (rank : 6)	NC score	0.622601 (rank : 4)
Query Neighborhood Hits	400	Target Neighborhood Hits	72	Shared Neighborhood Hits	11
SwissProt Accessions	P60484, O00633, O02679, Q6ICT7	Gene names	PTEN, MMAC1, TEP1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual- specificity protein phosphatase PTEN (EC 3.1.3.67) (EC 3.1.3.16) (EC 3.1.3.48) (Phosphatase and tensin homolog) (Mutated in multiple advanced cancers 1).

PTEN_MOUSE
θ value	9.52487e-34 (rank : 7)	NC score	0.622598 (rank : 5)
Query Neighborhood Hits	400	Target Neighborhood Hits	73	Shared Neighborhood Hits	11
SwissProt Accessions	O08586, Q542G1	Gene names	Pten, Mmac1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN (EC 3.1.3.67) (Mutated in multiple advanced cancers 1).

TPTE_HUMAN
θ value	2.96777e-27 (rank : 8)	NC score	0.604970 (rank : 6)
Query Neighborhood Hits	400	Target Neighborhood Hits	53	Shared Neighborhood Hits	9
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

AUXI_HUMAN
θ value	6.61148e-27 (rank : 9)	NC score	0.582311 (rank : 9)
Query Neighborhood Hits	400	Target Neighborhood Hits	99	Shared Neighborhood Hits	16
SwissProt Accessions	O75061, Q32M66, Q4G0K1, Q5T614, Q5T615	Gene names	DNAJC6, KIAA0473
Domain Architecture	No domain graphic available
Description	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6).

AUXI_MOUSE
θ value	8.63488e-27 (rank : 10)	NC score	0.583020 (rank : 8)
Query Neighborhood Hits	400	Target Neighborhood Hits	114	Shared Neighborhood Hits	19
SwissProt Accessions	Q80TZ3, Q6P2K9, Q8C7L9	Gene names	Dnajc6, Kiaa0473
Domain Architecture	No domain graphic available
Description	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6).

TPTE2_HUMAN
θ value	2.77775e-25 (rank : 11)	NC score	0.596186 (rank : 7)
Query Neighborhood Hits	400	Target Neighborhood Hits	68	Shared Neighborhood Hits	9
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

NFH_MOUSE
θ value	2.44474e-05 (rank : 12)	NC score	0.079660 (rank : 113)
Query Neighborhood Hits	400	Target Neighborhood Hits	2247	Shared Neighborhood Hits	174
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

HORN_HUMAN
θ value	4.1701e-05 (rank : 13)	NC score	0.087242 (rank : 84)
Query Neighborhood Hits	400	Target Neighborhood Hits	206	Shared Neighborhood Hits	21
SwissProt Accessions	Q86YZ3	Gene names	HRNR, S100A18
Domain Architecture	No domain graphic available
Description	Hornerin.

MDC1_MOUSE
θ value	0.000121331 (rank : 14)	NC score	0.117911 (rank : 28)
Query Neighborhood Hits	400	Target Neighborhood Hits	998	Shared Neighborhood Hits	121
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

RGS3_MOUSE
θ value	0.000270298 (rank : 15)	NC score	0.096096 (rank : 68)
Query Neighborhood Hits	400	Target Neighborhood Hits	1621	Shared Neighborhood Hits	164
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

MGRN1_HUMAN
θ value	0.000602161 (rank : 16)	NC score	0.081173 (rank : 105)
Query Neighborhood Hits	400	Target Neighborhood Hits	192	Shared Neighborhood Hits	12
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

CRK_HUMAN
θ value	0.00228821 (rank : 17)	NC score	0.156954 (rank : 14)
Query Neighborhood Hits	400	Target Neighborhood Hits	308	Shared Neighborhood Hits	85
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
θ value	0.00228821 (rank : 18)	NC score	0.155193 (rank : 15)
Query Neighborhood Hits	400	Target Neighborhood Hits	314	Shared Neighborhood Hits	86
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

SLAP2_MOUSE
θ value	0.00298849 (rank : 19)	NC score	0.160164 (rank : 13)
Query Neighborhood Hits	400	Target Neighborhood Hits	136	Shared Neighborhood Hits	70
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

TCGAP_HUMAN
θ value	0.00298849 (rank : 20)	NC score	0.076372 (rank : 129)
Query Neighborhood Hits	400	Target Neighborhood Hits	872	Shared Neighborhood Hits	119
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

PIAS3_MOUSE
θ value	0.00665767 (rank : 21)	NC score	0.053006 (rank : 309)
Query Neighborhood Hits	400	Target Neighborhood Hits	65	Shared Neighborhood Hits	10
SwissProt Accessions	O54714, Q80WF8, Q8R598	Gene names	Pias3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

LCP2_HUMAN
θ value	0.00869519 (rank : 22)	NC score	0.119834 (rank : 25)
Query Neighborhood Hits	400	Target Neighborhood Hits	531	Shared Neighborhood Hits	118
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

ANR38_MOUSE
θ value	0.0148317 (rank : 23)	NC score	0.034322 (rank : 383)
Query Neighborhood Hits	400	Target Neighborhood Hits	512	Shared Neighborhood Hits	25
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ATX2L_MOUSE
θ value	0.0148317 (rank : 24)	NC score	0.092535 (rank : 79)
Query Neighborhood Hits	400	Target Neighborhood Hits	401	Shared Neighborhood Hits	72
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

BSN_MOUSE
θ value	0.0148317 (rank : 25)	NC score	0.115370 (rank : 32)
Query Neighborhood Hits	400	Target Neighborhood Hits	2057	Shared Neighborhood Hits	193
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CBP_MOUSE
θ value	0.0148317 (rank : 26)	NC score	0.106643 (rank : 48)
Query Neighborhood Hits	400	Target Neighborhood Hits	1051	Shared Neighborhood Hits	126
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

PCDH7_HUMAN
θ value	0.0148317 (rank : 27)	NC score	0.030677 (rank : 402)
Query Neighborhood Hits	400	Target Neighborhood Hits	175	Shared Neighborhood Hits	15
SwissProt Accessions	O60245, O60246, O60247	Gene names	PCDH7, BHPCDH
Domain Architecture
Description	Protocadherin-7 precursor (Brain-heart protocadherin) (BH-Pcdh).

SLAP2_HUMAN
θ value	0.0148317 (rank : 28)	NC score	0.161171 (rank : 12)
Query Neighborhood Hits	400	Target Neighborhood Hits	139	Shared Neighborhood Hits	70
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

PCDA1_HUMAN
θ value	0.0193708 (rank : 29)	NC score	0.029291 (rank : 412)
Query Neighborhood Hits	400	Target Neighborhood Hits	199	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y5I3, O75288, Q9NRT7	Gene names	PCDHA1
Domain Architecture
Description	Protocadherin alpha 1 precursor (PCDH-alpha1).

SH2D5_HUMAN
θ value	0.0193708 (rank : 30)	NC score	0.099101 (rank : 63)
Query Neighborhood Hits	400	Target Neighborhood Hits	28	Shared Neighborhood Hits	16
SwissProt Accessions	Q6ZV89, Q5SSJ2	Gene names	SH2D5
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 5.

TAU_HUMAN
θ value	0.0193708 (rank : 31)	NC score	0.092271 (rank : 80)
Query Neighborhood Hits	400	Target Neighborhood Hits	448	Shared Neighborhood Hits	69
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

HSH2D_HUMAN
θ value	0.0252991 (rank : 32)	NC score	0.154258 (rank : 16)
Query Neighborhood Hits	400	Target Neighborhood Hits	159	Shared Neighborhood Hits	75
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

K1802_MOUSE
θ value	0.0252991 (rank : 33)	NC score	0.082362 (rank : 100)
Query Neighborhood Hits	400	Target Neighborhood Hits	1596	Shared Neighborhood Hits	142
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LATS2_MOUSE
θ value	0.0252991 (rank : 34)	NC score	0.021663 (rank : 449)
Query Neighborhood Hits	400	Target Neighborhood Hits	879	Shared Neighborhood Hits	49
SwissProt Accessions	Q7TSJ6, Q8CDJ4, Q9JMI3	Gene names	Lats2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein).

ZN750_HUMAN
θ value	0.0252991 (rank : 35)	NC score	0.073303 (rank : 147)
Query Neighborhood Hits	400	Target Neighborhood Hits	183	Shared Neighborhood Hits	32
SwissProt Accessions	Q32MQ0, Q9H899	Gene names	ZNF750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

BAG3_MOUSE
θ value	0.0330416 (rank : 36)	NC score	0.101601 (rank : 59)
Query Neighborhood Hits	400	Target Neighborhood Hits	513	Shared Neighborhood Hits	84
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

KCNH6_HUMAN
θ value	0.0330416 (rank : 37)	NC score	0.026718 (rank : 424)
Query Neighborhood Hits	400	Target Neighborhood Hits	222	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

SOX13_MOUSE
θ value	0.0330416 (rank : 38)	NC score	0.045895 (rank : 350)
Query Neighborhood Hits	400	Target Neighborhood Hits	495	Shared Neighborhood Hits	58
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

DOK1_HUMAN
θ value	0.0431538 (rank : 39)	NC score	0.045524 (rank : 351)
Query Neighborhood Hits	400	Target Neighborhood Hits	85	Shared Neighborhood Hits	10
SwissProt Accessions	Q99704, O43204, Q9UHG6	Gene names	DOK1
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)) (pp62).

SRMS_HUMAN
θ value	0.0431538 (rank : 40)	NC score	0.065430 (rank : 191)
Query Neighborhood Hits	400	Target Neighborhood Hits	946	Shared Neighborhood Hits	90
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

GPR37_HUMAN
θ value	0.0563607 (rank : 41)	NC score	0.015453 (rank : 481)
Query Neighborhood Hits	400	Target Neighborhood Hits	584	Shared Neighborhood Hits	9
SwissProt Accessions	O15354, O00348, O14768, Q8TD39	Gene names	GPR37
Domain Architecture
Description	Probable G-protein coupled receptor 37 precursor (Endothelin B receptor-like protein 1) (ETBR-LP-1) (Parkin-associated endothelin receptor-like receptor) (PAELR).

PRRT3_HUMAN
θ value	0.0563607 (rank : 42)	NC score	0.106271 (rank : 49)
Query Neighborhood Hits	400	Target Neighborhood Hits	998	Shared Neighborhood Hits	126
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SC24C_HUMAN
θ value	0.0563607 (rank : 43)	NC score	0.094031 (rank : 73)
Query Neighborhood Hits	400	Target Neighborhood Hits	662	Shared Neighborhood Hits	96
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SPT5H_MOUSE
θ value	0.0563607 (rank : 44)	NC score	0.101802 (rank : 58)
Query Neighborhood Hits	400	Target Neighborhood Hits	437	Shared Neighborhood Hits	84
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

SRRM2_MOUSE
θ value	0.0563607 (rank : 45)	NC score	0.122449 (rank : 24)
Query Neighborhood Hits	400	Target Neighborhood Hits	1470	Shared Neighborhood Hits	170
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

B3A3_HUMAN
θ value	0.0736092 (rank : 46)	NC score	0.029486 (rank : 410)
Query Neighborhood Hits	400	Target Neighborhood Hits	119	Shared Neighborhood Hits	25
SwissProt Accessions	P48751	Gene names	SLC4A3, AE3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3) (Cardiac/brain band 3-like protein) (CAE3/BAE3).

MUC2_HUMAN
θ value	0.0736092 (rank : 47)	NC score	0.078674 (rank : 115)
Query Neighborhood Hits	400	Target Neighborhood Hits	906	Shared Neighborhood Hits	94
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

CRKL_HUMAN
θ value	0.0961366 (rank : 48)	NC score	0.135869 (rank : 18)
Query Neighborhood Hits	400	Target Neighborhood Hits	313	Shared Neighborhood Hits	83
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

CSK_HUMAN
θ value	0.0961366 (rank : 49)	NC score	0.068246 (rank : 174)
Query Neighborhood Hits	400	Target Neighborhood Hits	1009	Shared Neighborhood Hits	93
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

CSK_MOUSE
θ value	0.0961366 (rank : 50)	NC score	0.068061 (rank : 175)
Query Neighborhood Hits	400	Target Neighborhood Hits	1009	Shared Neighborhood Hits	93
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

FYN_HUMAN
θ value	0.0961366 (rank : 51)	NC score	0.064848 (rank : 195)
Query Neighborhood Hits	400	Target Neighborhood Hits	1078	Shared Neighborhood Hits	95
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

SPT5H_HUMAN
θ value	0.0961366 (rank : 52)	NC score	0.099167 (rank : 62)
Query Neighborhood Hits	400	Target Neighborhood Hits	436	Shared Neighborhood Hits	82
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SRRM2_HUMAN
θ value	0.0961366 (rank : 53)	NC score	0.115848 (rank : 31)
Query Neighborhood Hits	400	Target Neighborhood Hits	1296	Shared Neighborhood Hits	148
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TRIM8_MOUSE
θ value	0.0961366 (rank : 54)	NC score	0.029432 (rank : 411)
Query Neighborhood Hits	400	Target Neighborhood Hits	674	Shared Neighborhood Hits	30
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

URFB1_HUMAN
θ value	0.0961366 (rank : 55)	NC score	0.064490 (rank : 200)
Query Neighborhood Hits	400	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	Q6BDS2, Q9NXE0	Gene names	UHRF1BP1, C6orf107
Domain Architecture	No domain graphic available
Description	UHRF1-binding protein 1 (Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1) (ICBP90-binding protein 1).

ARI1A_HUMAN
θ value	0.125558 (rank : 56)	NC score	0.108002 (rank : 44)
Query Neighborhood Hits	400	Target Neighborhood Hits	787	Shared Neighborhood Hits	123
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

HXA3_MOUSE
θ value	0.125558 (rank : 57)	NC score	0.036342 (rank : 374)
Query Neighborhood Hits	400	Target Neighborhood Hits	558	Shared Neighborhood Hits	64
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

PCDA4_HUMAN
θ value	0.125558 (rank : 58)	NC score	0.027428 (rank : 419)
Query Neighborhood Hits	400	Target Neighborhood Hits	193	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UN74, O75285	Gene names	PCDHA4
Domain Architecture
Description	Protocadherin alpha 4 precursor (PCDH-alpha4).

SP7_HUMAN
θ value	0.125558 (rank : 59)	NC score	0.009902 (rank : 518)
Query Neighborhood Hits	400	Target Neighborhood Hits	734	Shared Neighborhood Hits	28
SwissProt Accessions	Q8TDD2	Gene names	SP7, OSX
Domain Architecture	No domain graphic available
Description	Transcription factor Sp7 (Zinc finger protein osterix).

SRC_MOUSE
θ value	0.125558 (rank : 60)	NC score	0.064524 (rank : 198)
Query Neighborhood Hits	400	Target Neighborhood Hits	1033	Shared Neighborhood Hits	94
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

ABL1_HUMAN
θ value	0.163984 (rank : 61)	NC score	0.067463 (rank : 180)
Query Neighborhood Hits	400	Target Neighborhood Hits	1220	Shared Neighborhood Hits	124
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL1_MOUSE
θ value	0.163984 (rank : 62)	NC score	0.070288 (rank : 164)
Query Neighborhood Hits	400	Target Neighborhood Hits	1178	Shared Neighborhood Hits	136
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

MAST4_HUMAN
θ value	0.163984 (rank : 63)	NC score	0.044801 (rank : 354)
Query Neighborhood Hits	400	Target Neighborhood Hits	1804	Shared Neighborhood Hits	155
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

PCLO_MOUSE
θ value	0.163984 (rank : 64)	NC score	0.093214 (rank : 77)
Query Neighborhood Hits	400	Target Neighborhood Hits	2275	Shared Neighborhood Hits	190
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PDZD2_HUMAN
θ value	0.163984 (rank : 65)	NC score	0.062049 (rank : 217)
Query Neighborhood Hits	400	Target Neighborhood Hits	772	Shared Neighborhood Hits	81
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

CBP_HUMAN
θ value	0.21417 (rank : 66)	NC score	0.108010 (rank : 43)
Query Neighborhood Hits	400	Target Neighborhood Hits	941	Shared Neighborhood Hits	129
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CRKL_MOUSE
θ value	0.21417 (rank : 67)	NC score	0.137265 (rank : 17)
Query Neighborhood Hits	400	Target Neighborhood Hits	307	Shared Neighborhood Hits	83
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

FOXK1_MOUSE
θ value	0.21417 (rank : 68)	NC score	0.021405 (rank : 451)
Query Neighborhood Hits	400	Target Neighborhood Hits	215	Shared Neighborhood Hits	26
SwissProt Accessions	P42128, O35939	Gene names	Foxk1, Mnf
Domain Architecture
Description	Forkhead box protein K1 (Myocyte nuclear factor) (MNF).

PTN11_HUMAN
θ value	0.21417 (rank : 69)	NC score	0.075936 (rank : 133)
Query Neighborhood Hits	400	Target Neighborhood Hits	227	Shared Neighborhood Hits	78
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	0.21417 (rank : 70)	NC score	0.075946 (rank : 132)
Query Neighborhood Hits	400	Target Neighborhood Hits	227	Shared Neighborhood Hits	78
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

SRMS_MOUSE
θ value	0.21417 (rank : 71)	NC score	0.064193 (rank : 203)
Query Neighborhood Hits	400	Target Neighborhood Hits	964	Shared Neighborhood Hits	91
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

ALEX_HUMAN
θ value	0.279714 (rank : 72)	NC score	0.109862 (rank : 39)
Query Neighborhood Hits	400	Target Neighborhood Hits	361	Shared Neighborhood Hits	72
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

CO4A1_HUMAN
θ value	0.279714 (rank : 73)	NC score	0.036587 (rank : 372)
Query Neighborhood Hits	400	Target Neighborhood Hits	425	Shared Neighborhood Hits	75
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

JPH2_HUMAN
θ value	0.279714 (rank : 74)	NC score	0.053173 (rank : 306)
Query Neighborhood Hits	400	Target Neighborhood Hits	639	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

MLL3_HUMAN
θ value	0.279714 (rank : 75)	NC score	0.070544 (rank : 161)
Query Neighborhood Hits	400	Target Neighborhood Hits	1644	Shared Neighborhood Hits	137
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PCD12_HUMAN
θ value	0.279714 (rank : 76)	NC score	0.026332 (rank : 428)
Query Neighborhood Hits	400	Target Neighborhood Hits	203	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NPG4, Q6UXB6, Q96KB8, Q9H7Y6, Q9H8E0	Gene names	PCDH12
Domain Architecture
Description	Protocadherin-12 precursor (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cadherin-2) (VE-cad-2).

SP7_MOUSE
θ value	0.279714 (rank : 77)	NC score	0.009648 (rank : 520)
Query Neighborhood Hits	400	Target Neighborhood Hits	756	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VI67, Q8C5R3, Q8C6A7	Gene names	Sp7, Osx
Domain Architecture	No domain graphic available
Description	Transcription factor Sp7 (Zinc finger protein osterix) (C22).

SRGP1_HUMAN
θ value	0.279714 (rank : 78)	NC score	0.042804 (rank : 361)
Query Neighborhood Hits	400	Target Neighborhood Hits	390	Shared Neighborhood Hits	48
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

STAT1_HUMAN
θ value	0.279714 (rank : 79)	NC score	0.030341 (rank : 406)
Query Neighborhood Hits	400	Target Neighborhood Hits	128	Shared Neighborhood Hits	11
SwissProt Accessions	P42224	Gene names	STAT1
Domain Architecture
Description	Signal transducer and activator of transcription 1-alpha/beta (Transcription factor ISGF-3 components p91/p84).

STAT1_MOUSE
θ value	0.279714 (rank : 80)	NC score	0.030507 (rank : 405)
Query Neighborhood Hits	400	Target Neighborhood Hits	151	Shared Neighborhood Hits	10
SwissProt Accessions	P42225	Gene names	Stat1
Domain Architecture
Description	Signal transducer and activator of transcription 1.

SYNG_MOUSE
θ value	0.279714 (rank : 81)	NC score	0.049160 (rank : 331)
Query Neighborhood Hits	400	Target Neighborhood Hits	206	Shared Neighborhood Hits	28
SwissProt Accessions	Q5SV85, Q5SV84, Q6PHT6	Gene names	Ap1gbp1, Syng
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

ASXL1_HUMAN
θ value	0.365318 (rank : 82)	NC score	0.046773 (rank : 345)
Query Neighborhood Hits	400	Target Neighborhood Hits	260	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

BFSP2_MOUSE
θ value	0.365318 (rank : 83)	NC score	0.014871 (rank : 486)
Query Neighborhood Hits	400	Target Neighborhood Hits	423	Shared Neighborhood Hits	12
SwissProt Accessions	Q6NVD9, Q63832, Q6P5N4, Q8VDD6	Gene names	Bfsp2
Domain Architecture	No domain graphic available
Description	Phakinin (Beaded filament structural protein 2) (Lens fiber cell beaded filament protein CP 49) (CP49) (49 kDa cytoskeletal protein).

EWS_MOUSE
θ value	0.365318 (rank : 84)	NC score	0.052530 (rank : 311)
Query Neighborhood Hits	400	Target Neighborhood Hits	271	Shared Neighborhood Hits	36
SwissProt Accessions	Q61545	Gene names	Ewsr1, Ews, Ewsh
Domain Architecture
Description	RNA-binding protein EWS.

GOGA1_HUMAN
θ value	0.365318 (rank : 85)	NC score	0.011850 (rank : 503)
Query Neighborhood Hits	400	Target Neighborhood Hits	1222	Shared Neighborhood Hits	30
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

HXA3_HUMAN
θ value	0.365318 (rank : 86)	NC score	0.031252 (rank : 400)
Query Neighborhood Hits	400	Target Neighborhood Hits	535	Shared Neighborhood Hits	56
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

MUC13_MOUSE
θ value	0.365318 (rank : 87)	NC score	0.077348 (rank : 121)
Query Neighborhood Hits	400	Target Neighborhood Hits	447	Shared Neighborhood Hits	55
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

NCOA6_HUMAN
θ value	0.365318 (rank : 88)	NC score	0.105286 (rank : 51)
Query Neighborhood Hits	400	Target Neighborhood Hits	1202	Shared Neighborhood Hits	142
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

P55G_MOUSE
θ value	0.365318 (rank : 89)	NC score	0.124483 (rank : 22)
Query Neighborhood Hits	400	Target Neighborhood Hits	401	Shared Neighborhood Hits	74
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P85B_HUMAN
θ value	0.365318 (rank : 90)	NC score	0.123823 (rank : 23)
Query Neighborhood Hits	400	Target Neighborhood Hits	543	Shared Neighborhood Hits	87
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

P85B_MOUSE
θ value	0.365318 (rank : 91)	NC score	0.114133 (rank : 33)
Query Neighborhood Hits	400	Target Neighborhood Hits	519	Shared Neighborhood Hits	85
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PCDAD_HUMAN
θ value	0.365318 (rank : 92)	NC score	0.026043 (rank : 430)
Query Neighborhood Hits	400	Target Neighborhood Hits	197	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y5I0, O75277	Gene names	PCDHA13
Domain Architecture
Description	Protocadherin alpha 13 precursor (PCDH-alpha13).

PHLB1_HUMAN
θ value	0.365318 (rank : 93)	NC score	0.053387 (rank : 302)
Query Neighborhood Hits	400	Target Neighborhood Hits	1038	Shared Neighborhood Hits	85
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PHLB1_MOUSE
θ value	0.365318 (rank : 94)	NC score	0.054029 (rank : 296)
Query Neighborhood Hits	400	Target Neighborhood Hits	678	Shared Neighborhood Hits	61
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

SOCS3_MOUSE
θ value	0.365318 (rank : 95)	NC score	0.111204 (rank : 38)
Query Neighborhood Hits	400	Target Neighborhood Hits	72	Shared Neighborhood Hits	48
SwissProt Accessions	O35718, P97803, Q3U7X5	Gene names	Socs3, Cis3, Cish3
Domain Architecture
Description	Suppressor of cytokine signaling 3 (SOCS-3) (Cytokine-inducible SH2 protein 3) (CIS-3) (Protein EF-10).

ABL2_HUMAN
θ value	0.47712 (rank : 96)	NC score	0.065610 (rank : 189)
Query Neighborhood Hits	400	Target Neighborhood Hits	1045	Shared Neighborhood Hits	108
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

CD2L7_HUMAN
θ value	0.47712 (rank : 97)	NC score	0.038516 (rank : 366)
Query Neighborhood Hits	400	Target Neighborhood Hits	1275	Shared Neighborhood Hits	99
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

FGR_MOUSE
θ value	0.47712 (rank : 98)	NC score	0.067658 (rank : 179)
Query Neighborhood Hits	400	Target Neighborhood Hits	1069	Shared Neighborhood Hits	97
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

HRX_HUMAN
θ value	0.47712 (rank : 99)	NC score	0.059868 (rank : 239)
Query Neighborhood Hits	400	Target Neighborhood Hits	825	Shared Neighborhood Hits	89
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

HSH2D_MOUSE
θ value	0.47712 (rank : 100)	NC score	0.127524 (rank : 20)
Query Neighborhood Hits	400	Target Neighborhood Hits	124	Shared Neighborhood Hits	57
SwissProt Accessions	Q6VYH9, Q52KL3	Gene names	Hsh2d, Alx
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

MAML1_MOUSE
θ value	0.47712 (rank : 101)	NC score	0.067836 (rank : 178)
Query Neighborhood Hits	400	Target Neighborhood Hits	279	Shared Neighborhood Hits	57
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

OBSCN_HUMAN
θ value	0.47712 (rank : 102)	NC score	0.034426 (rank : 381)
Query Neighborhood Hits	400	Target Neighborhood Hits	1931	Shared Neighborhood Hits	131
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

OGFR_HUMAN
θ value	0.47712 (rank : 103)	NC score	0.093175 (rank : 78)
Query Neighborhood Hits	400	Target Neighborhood Hits	1582	Shared Neighborhood Hits	160
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PCDH1_HUMAN
θ value	0.47712 (rank : 104)	NC score	0.025977 (rank : 432)
Query Neighborhood Hits	400	Target Neighborhood Hits	174	Shared Neighborhood Hits	14
SwissProt Accessions	Q08174	Gene names	PCDH1
Domain Architecture
Description	Protocadherin-1 precursor (Protocadherin-42) (PC42) (Cadherin-like protein 1).

PCIF1_HUMAN
θ value	0.47712 (rank : 105)	NC score	0.037262 (rank : 370)
Query Neighborhood Hits	400	Target Neighborhood Hits	92	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H4Z3, Q9NT85	Gene names	PCIF1, C20orf67
Domain Architecture
Description	Phosphorylated CTD-interacting factor 1.

SH2D5_MOUSE
θ value	0.47712 (rank : 106)	NC score	0.076977 (rank : 123)
Query Neighborhood Hits	400	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	Q8JZW5	Gene names	Sh2d5
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 5.

SHE_MOUSE
θ value	0.47712 (rank : 107)	NC score	0.108799 (rank : 41)
Query Neighborhood Hits	400	Target Neighborhood Hits	169	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BSD5, Q3TZT0	Gene names	She
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

WASP_MOUSE
θ value	0.47712 (rank : 108)	NC score	0.068642 (rank : 170)
Query Neighborhood Hits	400	Target Neighborhood Hits	223	Shared Neighborhood Hits	53
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

ZCH14_HUMAN
θ value	0.47712 (rank : 109)	NC score	0.048220 (rank : 336)
Query Neighborhood Hits	400	Target Neighborhood Hits	117	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WYQ9, O60324, Q9UFP0	Gene names	ZCCHC14, KIAA0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

APXL_HUMAN
θ value	0.62314 (rank : 110)	NC score	0.064674 (rank : 196)
Query Neighborhood Hits	400	Target Neighborhood Hits	553	Shared Neighborhood Hits	53
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

DEN1A_HUMAN
θ value	0.62314 (rank : 111)	NC score	0.031753 (rank : 397)
Query Neighborhood Hits	400	Target Neighborhood Hits	176	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

DGKK_HUMAN
θ value	0.62314 (rank : 112)	NC score	0.060982 (rank : 230)
Query Neighborhood Hits	400	Target Neighborhood Hits	378	Shared Neighborhood Hits	66
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

LR37A_HUMAN
θ value	0.62314 (rank : 113)	NC score	0.049966 (rank : 329)
Query Neighborhood Hits	400	Target Neighborhood Hits	720	Shared Neighborhood Hits	70
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

MTSS1_HUMAN
θ value	0.62314 (rank : 114)	NC score	0.058292 (rank : 260)
Query Neighborhood Hits	400	Target Neighborhood Hits	504	Shared Neighborhood Hits	57
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

NCOA3_MOUSE
θ value	0.62314 (rank : 115)	NC score	0.034728 (rank : 380)
Query Neighborhood Hits	400	Target Neighborhood Hits	203	Shared Neighborhood Hits	43
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

NFIB_HUMAN
θ value	0.62314 (rank : 116)	NC score	0.031462 (rank : 398)
Query Neighborhood Hits	400	Target Neighborhood Hits	66	Shared Neighborhood Hits	18
SwissProt Accessions	O00712, O00166, Q12858, Q96J45	Gene names	NFIB
Domain Architecture
Description	Nuclear factor 1 B-type (Nuclear factor 1/B) (NF1-B) (NFI-B) (NF-I/B) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

STAB1_HUMAN
θ value	0.62314 (rank : 117)	NC score	0.012002 (rank : 502)
Query Neighborhood Hits	400	Target Neighborhood Hits	546	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

YETS2_MOUSE
θ value	0.62314 (rank : 118)	NC score	0.047156 (rank : 342)
Query Neighborhood Hits	400	Target Neighborhood Hits	278	Shared Neighborhood Hits	39
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

BAT2_MOUSE
θ value	0.813845 (rank : 119)	NC score	0.097143 (rank : 66)
Query Neighborhood Hits	400	Target Neighborhood Hits	947	Shared Neighborhood Hits	139
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

GPTC8_HUMAN
θ value	0.813845 (rank : 120)	NC score	0.054986 (rank : 287)
Query Neighborhood Hits	400	Target Neighborhood Hits	366	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

GRAP2_HUMAN
θ value	0.813845 (rank : 121)	NC score	0.129923 (rank : 19)
Query Neighborhood Hits	400	Target Neighborhood Hits	304	Shared Neighborhood Hits	85
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

GRB14_MOUSE
θ value	0.813845 (rank : 122)	NC score	0.107963 (rank : 45)
Query Neighborhood Hits	400	Target Neighborhood Hits	149	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JLM9, Q3UI77, Q8VDI2, Q9CR03	Gene names	Grb14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

HORN_MOUSE
θ value	0.813845 (rank : 123)	NC score	0.049126 (rank : 332)
Query Neighborhood Hits	400	Target Neighborhood Hits	218	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

MAP1B_MOUSE
θ value	0.813845 (rank : 124)	NC score	0.038432 (rank : 368)
Query Neighborhood Hits	400	Target Neighborhood Hits	977	Shared Neighborhood Hits	62
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MEFV_HUMAN
θ value	0.813845 (rank : 125)	NC score	0.014587 (rank : 487)
Query Neighborhood Hits	400	Target Neighborhood Hits	431	Shared Neighborhood Hits	36
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

NCOA6_MOUSE
θ value	0.813845 (rank : 126)	NC score	0.098194 (rank : 65)
Query Neighborhood Hits	400	Target Neighborhood Hits	1076	Shared Neighborhood Hits	123
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NF1_HUMAN
θ value	0.813845 (rank : 127)	NC score	0.022825 (rank : 444)
Query Neighborhood Hits	400	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	P21359, O00662, Q14284, Q14930, Q9UMK3	Gene names	NF1
Domain Architecture
Description	Neurofibromin (Neurofibromatosis-related protein NF-1) [Contains: Neurofibromin truncated].

P3C2A_MOUSE
θ value	0.813845 (rank : 128)	NC score	0.020729 (rank : 456)
Query Neighborhood Hits	400	Target Neighborhood Hits	181	Shared Neighborhood Hits	20
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

P55G_HUMAN
θ value	0.813845 (rank : 129)	NC score	0.119608 (rank : 26)
Query Neighborhood Hits	400	Target Neighborhood Hits	451	Shared Neighborhood Hits	76
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

PCDA9_HUMAN
θ value	0.813845 (rank : 130)	NC score	0.026042 (rank : 431)
Query Neighborhood Hits	400	Target Neighborhood Hits	203	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y5H5, O15053	Gene names	PCDHA9, KIAA0345
Domain Architecture
Description	Protocadherin alpha 9 precursor (PCDH-alpha9).

PGCA_MOUSE
θ value	0.813845 (rank : 131)	NC score	0.035303 (rank : 377)
Query Neighborhood Hits	400	Target Neighborhood Hits	643	Shared Neighborhood Hits	61
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

RIN1_HUMAN
θ value	0.813845 (rank : 132)	NC score	0.069663 (rank : 165)
Query Neighborhood Hits	400	Target Neighborhood Hits	52	Shared Neighborhood Hits	11
SwissProt Accessions	Q13671, O15010, Q00427, Q96CC8	Gene names	RIN1
Domain Architecture
Description	Ras and Rab interactor 1 (Ras interaction/interference protein 1) (Ras inhibitor JC99).

SHC3_MOUSE
θ value	0.813845 (rank : 133)	NC score	0.084232 (rank : 95)
Query Neighborhood Hits	400	Target Neighborhood Hits	151	Shared Neighborhood Hits	68
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

SYN1_MOUSE
θ value	0.813845 (rank : 134)	NC score	0.094644 (rank : 71)
Query Neighborhood Hits	400	Target Neighborhood Hits	363	Shared Neighborhood Hits	82
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

TBCD2_HUMAN
θ value	0.813845 (rank : 135)	NC score	0.029892 (rank : 407)
Query Neighborhood Hits	400	Target Neighborhood Hits	419	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

WASF3_HUMAN
θ value	0.813845 (rank : 136)	NC score	0.061594 (rank : 222)
Query Neighborhood Hits	400	Target Neighborhood Hits	204	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

CSPG3_MOUSE
θ value	1.06291 (rank : 137)	NC score	0.021049 (rank : 454)
Query Neighborhood Hits	400	Target Neighborhood Hits	657	Shared Neighborhood Hits	52
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

DOCK4_HUMAN
θ value	1.06291 (rank : 138)	NC score	0.030865 (rank : 401)
Query Neighborhood Hits	400	Target Neighborhood Hits	237	Shared Neighborhood Hits	42
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

LN28B_HUMAN
θ value	1.06291 (rank : 139)	NC score	0.034959 (rank : 378)
Query Neighborhood Hits	400	Target Neighborhood Hits	66	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZN17	Gene names	LIN28B, CSDD2
Domain Architecture	No domain graphic available
Description	Lin-28 homolog B.

MPDZ_MOUSE
θ value	1.06291 (rank : 140)	NC score	0.016061 (rank : 477)
Query Neighborhood Hits	400	Target Neighborhood Hits	298	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

NACAM_MOUSE
θ value	1.06291 (rank : 141)	NC score	0.094413 (rank : 72)
Query Neighborhood Hits	400	Target Neighborhood Hits	1866	Shared Neighborhood Hits	186
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NP1L3_MOUSE
θ value	1.06291 (rank : 142)	NC score	0.026098 (rank : 429)
Query Neighborhood Hits	400	Target Neighborhood Hits	233	Shared Neighborhood Hits	15
SwissProt Accessions	Q794H2, O54802	Gene names	Nap1l3, Mb20
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 3 (Brain-specific protein MB20).

P85A_HUMAN
θ value	1.06291 (rank : 143)	NC score	0.105188 (rank : 52)
Query Neighborhood Hits	400	Target Neighborhood Hits	479	Shared Neighborhood Hits	78
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85A_MOUSE
θ value	1.06291 (rank : 144)	NC score	0.109842 (rank : 40)
Query Neighborhood Hits	400	Target Neighborhood Hits	435	Shared Neighborhood Hits	80
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

PIAS3_HUMAN
θ value	1.06291 (rank : 145)	NC score	0.039111 (rank : 365)
Query Neighborhood Hits	400	Target Neighborhood Hits	58	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y6X2, Q9UFI3	Gene names	PIAS3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

REXO1_MOUSE
θ value	1.06291 (rank : 146)	NC score	0.038498 (rank : 367)
Query Neighborhood Hits	400	Target Neighborhood Hits	166	Shared Neighborhood Hits	24
SwissProt Accessions	Q7TT28, Q3UMP1, Q69ZR0, Q6NSQ6, Q6PI95, Q9DA29	Gene names	Rexo1, Kiaa1138, Tceb3bp1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1).

SOCS2_MOUSE
θ value	1.06291 (rank : 147)	NC score	0.083669 (rank : 98)
Query Neighborhood Hits	400	Target Neighborhood Hits	94	Shared Neighborhood Hits	51
SwissProt Accessions	O35717	Gene names	Socs2, Cis2, Cish2
Domain Architecture
Description	Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2) (CIS-2).

SOCS3_HUMAN
θ value	1.06291 (rank : 148)	NC score	0.107899 (rank : 46)
Query Neighborhood Hits	400	Target Neighborhood Hits	77	Shared Neighborhood Hits	49
SwissProt Accessions	O14543, O14509	Gene names	SOCS3, CIS3, SSI3
Domain Architecture
Description	Suppressor of cytokine signaling 3 (SOCS-3) (Cytokine-inducible SH2 protein 3) (CIS-3) (STAT-induced STAT inhibitor 3) (SSI-3).

SPAG5_MOUSE
θ value	1.06291 (rank : 149)	NC score	0.019842 (rank : 460)
Query Neighborhood Hits	400	Target Neighborhood Hits	612	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

SRC_HUMAN
θ value	1.06291 (rank : 150)	NC score	0.062928 (rank : 209)
Query Neighborhood Hits	400	Target Neighborhood Hits	1058	Shared Neighborhood Hits	95
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

SRRM1_HUMAN
θ value	1.06291 (rank : 151)	NC score	0.111302 (rank : 37)
Query Neighborhood Hits	400	Target Neighborhood Hits	690	Shared Neighborhood Hits	104
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

TRIM8_HUMAN
θ value	1.06291 (rank : 152)	NC score	0.024046 (rank : 439)
Query Neighborhood Hits	400	Target Neighborhood Hits	650	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

UBE4B_HUMAN
θ value	1.06291 (rank : 153)	NC score	0.046239 (rank : 349)
Query Neighborhood Hits	400	Target Neighborhood Hits	158	Shared Neighborhood Hits	37
SwissProt Accessions	O95155, O75169, O95338, Q5SZ12, Q5SZ16, Q96QD4, Q9BYI7	Gene names	UBE4B, HDNB1, KIAA0684, UFD2
Domain Architecture
Description	Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Homozygously deleted in neuroblastoma 1).

ATX1_MOUSE
θ value	1.38821 (rank : 154)	NC score	0.044989 (rank : 352)
Query Neighborhood Hits	400	Target Neighborhood Hits	264	Shared Neighborhood Hits	40
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

CO4A5_HUMAN
θ value	1.38821 (rank : 155)	NC score	0.040528 (rank : 363)
Query Neighborhood Hits	400	Target Neighborhood Hits	383	Shared Neighborhood Hits	63
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

EWS_HUMAN
θ value	1.38821 (rank : 156)	NC score	0.047961 (rank : 337)
Query Neighborhood Hits	400	Target Neighborhood Hits	249	Shared Neighborhood Hits	35
SwissProt Accessions	Q01844, Q92635	Gene names	EWSR1, EWS
Domain Architecture
Description	RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein).

GAB2_HUMAN
θ value	1.38821 (rank : 157)	NC score	0.044955 (rank : 353)
Query Neighborhood Hits	400	Target Neighborhood Hits	188	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

HGS_HUMAN
θ value	1.38821 (rank : 158)	NC score	0.033878 (rank : 387)
Query Neighborhood Hits	400	Target Neighborhood Hits	517	Shared Neighborhood Hits	52
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

MAML3_HUMAN
θ value	1.38821 (rank : 159)	NC score	0.083782 (rank : 97)
Query Neighborhood Hits	400	Target Neighborhood Hits	323	Shared Neighborhood Hits	71
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

MK15_HUMAN
θ value	1.38821 (rank : 160)	NC score	0.032466 (rank : 394)
Query Neighborhood Hits	400	Target Neighborhood Hits	1038	Shared Neighborhood Hits	82
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

NFIB_MOUSE
θ value	1.38821 (rank : 161)	NC score	0.030634 (rank : 403)
Query Neighborhood Hits	400	Target Neighborhood Hits	72	Shared Neighborhood Hits	19
SwissProt Accessions	P97863, P70252, P70253, P70254, Q9R1G4	Gene names	Nfib
Domain Architecture
Description	Nuclear factor 1 B-type (Nuclear factor 1/B) (NF1-B) (NFI-B) (NF-I/B) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

PROX1_MOUSE
θ value	1.38821 (rank : 162)	NC score	0.035855 (rank : 375)
Query Neighborhood Hits	400	Target Neighborhood Hits	184	Shared Neighborhood Hits	7
SwissProt Accessions	P48437, O88478, Q3UPV1, Q543D8	Gene names	Prox1
Domain Architecture
Description	Homeobox prospero-like protein PROX1 (PROX 1).

SEPT9_HUMAN
θ value	1.38821 (rank : 163)	NC score	0.047840 (rank : 338)
Query Neighborhood Hits	400	Target Neighborhood Hits	706	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

SRRM1_MOUSE
θ value	1.38821 (rank : 164)	NC score	0.118839 (rank : 27)
Query Neighborhood Hits	400	Target Neighborhood Hits	966	Shared Neighborhood Hits	138
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TAU_MOUSE
θ value	1.38821 (rank : 165)	NC score	0.074917 (rank : 139)
Query Neighborhood Hits	400	Target Neighborhood Hits	502	Shared Neighborhood Hits	83
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TBL1R_HUMAN
θ value	1.38821 (rank : 166)	NC score	0.008974 (rank : 524)
Query Neighborhood Hits	400	Target Neighborhood Hits	327	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BZK7, Q9H2I1, Q9H9A1	Gene names	TBL1XR1, IRA1, TBLR1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1).

TBL1R_MOUSE
θ value	1.38821 (rank : 167)	NC score	0.008989 (rank : 523)
Query Neighborhood Hits	400	Target Neighborhood Hits	329	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BHJ5, Q3UWL6, Q8CBG4, Q8VEG3, Q9EQD4	Gene names	Tbl1xr1, Ira1, Tblr1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1).

ZIC5_HUMAN
θ value	1.38821 (rank : 168)	NC score	0.005320 (rank : 537)
Query Neighborhood Hits	400	Target Neighborhood Hits	774	Shared Neighborhood Hits	37
SwissProt Accessions	Q96T25	Gene names	ZIC5
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZIC 5 (Zinc finger protein of the cerebellum 5).

ZIM10_HUMAN
θ value	1.38821 (rank : 169)	NC score	0.064408 (rank : 202)
Query Neighborhood Hits	400	Target Neighborhood Hits	577	Shared Neighborhood Hits	89
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ARI1B_HUMAN
θ value	1.81305 (rank : 170)	NC score	0.095666 (rank : 69)
Query Neighborhood Hits	400	Target Neighborhood Hits	567	Shared Neighborhood Hits	103
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

BCL6_HUMAN
θ value	1.81305 (rank : 171)	NC score	0.000883 (rank : 543)
Query Neighborhood Hits	400	Target Neighborhood Hits	922	Shared Neighborhood Hits	39
SwissProt Accessions	P41182	Gene names	BCL6, BCL5, LAZ3, ZBTB27, ZNF51
Domain Architecture
Description	B-cell lymphoma 6 protein (BCL-6) (Zinc finger protein 51) (LAZ-3 protein) (BCL-5) (Zinc finger and BTB domain-containing protein 27).

CDSN_HUMAN
θ value	1.81305 (rank : 172)	NC score	0.046439 (rank : 347)
Query Neighborhood Hits	400	Target Neighborhood Hits	84	Shared Neighborhood Hits	19
SwissProt Accessions	Q15517, O43509, Q5SQ85, Q5STD2, Q7LA70, Q7LA71, Q86Z04, Q8IZU4, Q8IZU5, Q8IZU6, Q8N5P3, Q95IF9, Q9NP52, Q9NPE0, Q9NPG5, Q9NRH4, Q9NRH5, Q9NRH6, Q9NRH7, Q9NRH8, Q9UBH8, Q9UIN6, Q9UIN7, Q9UIN8, Q9UIN9, Q9UIP0	Gene names	CDSN
Domain Architecture	No domain graphic available
Description	Corneodesmosin precursor (S protein).

CIC_MOUSE
θ value	1.81305 (rank : 173)	NC score	0.080096 (rank : 111)
Query Neighborhood Hits	400	Target Neighborhood Hits	742	Shared Neighborhood Hits	119
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CO2A1_MOUSE
θ value	1.81305 (rank : 174)	NC score	0.035758 (rank : 376)
Query Neighborhood Hits	400	Target Neighborhood Hits	483	Shared Neighborhood Hits	68
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

FGR_HUMAN
θ value	1.81305 (rank : 175)	NC score	0.062933 (rank : 207)
Query Neighborhood Hits	400	Target Neighborhood Hits	1067	Shared Neighborhood Hits	94
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

GAB2_MOUSE
θ value	1.81305 (rank : 176)	NC score	0.047286 (rank : 340)
Query Neighborhood Hits	400	Target Neighborhood Hits	220	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

HTF4_HUMAN
θ value	1.81305 (rank : 177)	NC score	0.022856 (rank : 443)
Query Neighborhood Hits	400	Target Neighborhood Hits	152	Shared Neighborhood Hits	15
SwissProt Accessions	Q99081	Gene names	TCF12, HEB, HTF4
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4).

HXA4_HUMAN
θ value	1.81305 (rank : 178)	NC score	0.016138 (rank : 475)
Query Neighborhood Hits	400	Target Neighborhood Hits	370	Shared Neighborhood Hits	33
SwissProt Accessions	Q00056, O43366	Gene names	HOXA4, HOX1D
Domain Architecture
Description	Homeobox protein Hox-A4 (Hox-1D) (Hox-1.4).

LY75_MOUSE
θ value	1.81305 (rank : 179)	NC score	0.014400 (rank : 488)
Query Neighborhood Hits	400	Target Neighborhood Hits	155	Shared Neighborhood Hits	6
SwissProt Accessions	Q60767, Q8C7T3, Q91XL8, Q9QUZ6	Gene names	Ly75, Cd205
Domain Architecture
Description	Lymphocyte antigen 75 precursor (DEC-205) (CD205 antigen).

MTSS1_MOUSE
θ value	1.81305 (rank : 180)	NC score	0.057241 (rank : 268)
Query Neighborhood Hits	400	Target Neighborhood Hits	592	Shared Neighborhood Hits	70
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

PHAR3_MOUSE
θ value	1.81305 (rank : 181)	NC score	0.033200 (rank : 389)
Query Neighborhood Hits	400	Target Neighborhood Hits	206	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BYK5, Q8BYS8, Q8C058, Q9DB87	Gene names	Phactr3, Scapin1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

PTPRG_MOUSE
θ value	1.81305 (rank : 182)	NC score	0.017185 (rank : 469)
Query Neighborhood Hits	400	Target Neighborhood Hits	260	Shared Neighborhood Hits	22
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

REPS1_HUMAN
θ value	1.81305 (rank : 183)	NC score	0.028253 (rank : 417)
Query Neighborhood Hits	400	Target Neighborhood Hits	205	Shared Neighborhood Hits	22
SwissProt Accessions	Q96D71, Q8NDR7, Q8WU62, Q9BXY9	Gene names	REPS1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

SEPT9_MOUSE
θ value	1.81305 (rank : 184)	NC score	0.024912 (rank : 436)
Query Neighborhood Hits	400	Target Neighborhood Hits	238	Shared Neighborhood Hits	27
SwissProt Accessions	Q80UG5, Q3URP2, Q80TM7, Q9QYX9	Gene names	Sept9, Kiaa0991, Sint1
Domain Architecture	No domain graphic available
Description	Septin-9 (SL3-3 integration site 1 protein).

SHE_HUMAN
θ value	1.81305 (rank : 185)	NC score	0.095004 (rank : 70)
Query Neighborhood Hits	400	Target Neighborhood Hits	164	Shared Neighborhood Hits	71
SwissProt Accessions	Q5VZ18, Q8TEQ5	Gene names	SHE
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

SREC_HUMAN
θ value	1.81305 (rank : 186)	NC score	0.011568 (rank : 507)
Query Neighborhood Hits	400	Target Neighborhood Hits	645	Shared Neighborhood Hits	32
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

ZC3H6_MOUSE
θ value	1.81305 (rank : 187)	NC score	0.023910 (rank : 440)
Query Neighborhood Hits	400	Target Neighborhood Hits	239	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

ABCA7_HUMAN
θ value	2.36792 (rank : 188)	NC score	0.006541 (rank : 533)
Query Neighborhood Hits	400	Target Neighborhood Hits	144	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IZY2, Q96S58, Q9BZC4, Q9NR73, Q9UKP8	Gene names	ABCA7
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 7 (Macrophage ABC transporter) (Autoantigen SS-N) (ABCA-SSN).

ALMS1_MOUSE
θ value	2.36792 (rank : 189)	NC score	0.033912 (rank : 386)
Query Neighborhood Hits	400	Target Neighborhood Hits	181	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K4E0, Q6A084, Q8C9N9	Gene names	Alms1, Kiaa0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1 homolog.

ANXA7_HUMAN
θ value	2.36792 (rank : 190)	NC score	0.018420 (rank : 464)
Query Neighborhood Hits	400	Target Neighborhood Hits	168	Shared Neighborhood Hits	32
SwissProt Accessions	P20073	Gene names	ANXA7, ANX7, SNX
Domain Architecture
Description	Annexin A7 (Annexin VII) (Synexin).

AUTS2_HUMAN
θ value	2.36792 (rank : 191)	NC score	0.065494 (rank : 190)
Query Neighborhood Hits	400	Target Neighborhood Hits	342	Shared Neighborhood Hits	62
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

BAG3_HUMAN
θ value	2.36792 (rank : 192)	NC score	0.075960 (rank : 131)
Query Neighborhood Hits	400	Target Neighborhood Hits	314	Shared Neighborhood Hits	57
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

BC11A_HUMAN
θ value	2.36792 (rank : 193)	NC score	0.005805 (rank : 534)
Query Neighborhood Hits	400	Target Neighborhood Hits	745	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H165, Q86W14, Q8WU92, Q96JL6, Q9H163, Q9H164, Q9H3G9, Q9NWA7	Gene names	BCL11A, CTIP1, EVI9, KIAA1809
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11A (B-cell CLL/lymphoma 11A) (COUP-TF- interacting protein 1) (Ecotropic viral integration site 9 protein) (EVI-9).

BC11A_MOUSE
θ value	2.36792 (rank : 194)	NC score	0.007498 (rank : 530)
Query Neighborhood Hits	400	Target Neighborhood Hits	732	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QYE3, Q80T89, Q8BLC7, Q8BLR4, Q8BWX3, Q921V4, Q9D0V2, Q9JIT4, Q9JLK8, Q9JLK9	Gene names	Bcl11a, Ctip1, Evi9, Kiaa1809
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11A (B-cell CLL/lymphoma 11A) (COUP-TF- interacting protein 1) (Ecotropic viral integration site 9 protein) (EVI-9).

BLK_MOUSE
θ value	2.36792 (rank : 195)	NC score	0.062491 (rank : 213)
Query Neighborhood Hits	400	Target Neighborhood Hits	992	Shared Neighborhood Hits	85
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BTK_HUMAN
θ value	2.36792 (rank : 196)	NC score	0.063037 (rank : 206)
Query Neighborhood Hits	400	Target Neighborhood Hits	1026	Shared Neighborhood Hits	86
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

CHIO_HUMAN
θ value	2.36792 (rank : 197)	NC score	0.049364 (rank : 330)
Query Neighborhood Hits	400	Target Neighborhood Hits	220	Shared Neighborhood Hits	55
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

DOCK4_MOUSE
θ value	2.36792 (rank : 198)	NC score	0.028738 (rank : 413)
Query Neighborhood Hits	400	Target Neighborhood Hits	210	Shared Neighborhood Hits	33
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

FOXO1_MOUSE
θ value	2.36792 (rank : 199)	NC score	0.013873 (rank : 491)
Query Neighborhood Hits	400	Target Neighborhood Hits	118	Shared Neighborhood Hits	12
SwissProt Accessions	Q9R1E0	Gene names	Foxo1a, Fkhr, Foxo1
Domain Architecture
Description	Forkhead box protein O1A (Forkhead in rhabdomyosarcoma).

GA2L2_MOUSE
θ value	2.36792 (rank : 200)	NC score	0.050954 (rank : 323)
Query Neighborhood Hits	400	Target Neighborhood Hits	395	Shared Neighborhood Hits	68
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

GRAP2_MOUSE
θ value	2.36792 (rank : 201)	NC score	0.124893 (rank : 21)
Query Neighborhood Hits	400	Target Neighborhood Hits	297	Shared Neighborhood Hits	83
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

GRAP_MOUSE
θ value	2.36792 (rank : 202)	NC score	0.117684 (rank : 29)
Query Neighborhood Hits	400	Target Neighborhood Hits	309	Shared Neighborhood Hits	82
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

GRB10_MOUSE
θ value	2.36792 (rank : 203)	NC score	0.086953 (rank : 86)
Query Neighborhood Hits	400	Target Neighborhood Hits	156	Shared Neighborhood Hits	65
SwissProt Accessions	Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5	Gene names	Grb10
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein).

JIP1_HUMAN
θ value	2.36792 (rank : 204)	NC score	0.044342 (rank : 356)
Query Neighborhood Hits	400	Target Neighborhood Hits	271	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

K1543_MOUSE
θ value	2.36792 (rank : 205)	NC score	0.059563 (rank : 244)
Query Neighborhood Hits	400	Target Neighborhood Hits	497	Shared Neighborhood Hits	73
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

K2002_MOUSE
θ value	2.36792 (rank : 206)	NC score	0.048231 (rank : 335)
Query Neighborhood Hits	400	Target Neighborhood Hits	267	Shared Neighborhood Hits	12
SwissProt Accessions	Q69Z38, Q8R365	Gene names	Kiaa2002
Domain Architecture	No domain graphic available
Description	Uncharacterized tyrosine-protein kinase KIAA2002 (EC 2.7.10.2).

LRIG1_MOUSE
θ value	2.36792 (rank : 207)	NC score	0.002787 (rank : 540)
Query Neighborhood Hits	400	Target Neighborhood Hits	627	Shared Neighborhood Hits	14
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

M4K4_MOUSE
θ value	2.36792 (rank : 208)	NC score	0.027165 (rank : 422)
Query Neighborhood Hits	400	Target Neighborhood Hits	1560	Shared Neighborhood Hits	73
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MAST3_HUMAN
θ value	2.36792 (rank : 209)	NC score	0.030555 (rank : 404)
Query Neighborhood Hits	400	Target Neighborhood Hits	1128	Shared Neighborhood Hits	89
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

MEGF9_MOUSE
θ value	2.36792 (rank : 210)	NC score	0.028722 (rank : 414)
Query Neighborhood Hits	400	Target Neighborhood Hits	896	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MILK1_HUMAN
θ value	2.36792 (rank : 211)	NC score	0.054845 (rank : 289)
Query Neighborhood Hits	400	Target Neighborhood Hits	427	Shared Neighborhood Hits	72
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MILK1_MOUSE
θ value	2.36792 (rank : 212)	NC score	0.061801 (rank : 221)
Query Neighborhood Hits	400	Target Neighborhood Hits	788	Shared Neighborhood Hits	101
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MYCB2_MOUSE
θ value	2.36792 (rank : 213)	NC score	0.026691 (rank : 425)
Query Neighborhood Hits	400	Target Neighborhood Hits	307	Shared Neighborhood Hits	32
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

OTX1_HUMAN
θ value	2.36792 (rank : 214)	NC score	0.015890 (rank : 478)
Query Neighborhood Hits	400	Target Neighborhood Hits	379	Shared Neighborhood Hits	23
SwissProt Accessions	P32242, Q53TG6	Gene names	OTX1
Domain Architecture
Description	Homeobox protein OTX1.

OTX1_MOUSE
θ value	2.36792 (rank : 215)	NC score	0.015611 (rank : 479)
Query Neighborhood Hits	400	Target Neighborhood Hits	372	Shared Neighborhood Hits	20
SwissProt Accessions	P80205	Gene names	Otx1, Otx-1
Domain Architecture
Description	Homeobox protein OTX1.

PABP1_HUMAN
θ value	2.36792 (rank : 216)	NC score	0.013862 (rank : 492)
Query Neighborhood Hits	400	Target Neighborhood Hits	269	Shared Neighborhood Hits	17
SwissProt Accessions	P11940, Q15097, Q93004	Gene names	PABPC1, PAB1, PABP1, PABPC2
Domain Architecture
Description	Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1).

PABP1_MOUSE
θ value	2.36792 (rank : 217)	NC score	0.013648 (rank : 494)
Query Neighborhood Hits	400	Target Neighborhood Hits	278	Shared Neighborhood Hits	17
SwissProt Accessions	P29341	Gene names	Pabpc1, Pabp1
Domain Architecture
Description	Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1).

PPRB_MOUSE
θ value	2.36792 (rank : 218)	NC score	0.058866 (rank : 253)
Query Neighborhood Hits	400	Target Neighborhood Hits	354	Shared Neighborhood Hits	65
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

PROX1_HUMAN
θ value	2.36792 (rank : 219)	NC score	0.032923 (rank : 391)
Query Neighborhood Hits	400	Target Neighborhood Hits	171	Shared Neighborhood Hits	6
SwissProt Accessions	Q92786, Q5SW76, Q8TB91	Gene names	PROX1
Domain Architecture
Description	Homeobox prospero-like protein PROX1 (PROX 1).

R3HD2_MOUSE
θ value	2.36792 (rank : 220)	NC score	0.061409 (rank : 225)
Query Neighborhood Hits	400	Target Neighborhood Hits	397	Shared Neighborhood Hits	68
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

RPB1_HUMAN
θ value	2.36792 (rank : 221)	NC score	0.072381 (rank : 153)
Query Neighborhood Hits	400	Target Neighborhood Hits	362	Shared Neighborhood Hits	72
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	2.36792 (rank : 222)	NC score	0.072446 (rank : 152)
Query Neighborhood Hits	400	Target Neighborhood Hits	363	Shared Neighborhood Hits	71
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

SHAN1_HUMAN
θ value	2.36792 (rank : 223)	NC score	0.051827 (rank : 316)
Query Neighborhood Hits	400	Target Neighborhood Hits	1041	Shared Neighborhood Hits	123
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SNPC4_HUMAN
θ value	2.36792 (rank : 224)	NC score	0.055240 (rank : 284)
Query Neighborhood Hits	400	Target Neighborhood Hits	589	Shared Neighborhood Hits	85
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

SYN1_HUMAN
θ value	2.36792 (rank : 225)	NC score	0.093741 (rank : 75)
Query Neighborhood Hits	400	Target Neighborhood Hits	419	Shared Neighborhood Hits	92
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

TLE1_MOUSE
θ value	2.36792 (rank : 226)	NC score	0.014235 (rank : 490)
Query Neighborhood Hits	400	Target Neighborhood Hits	491	Shared Neighborhood Hits	46
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

TM16H_HUMAN
θ value	2.36792 (rank : 227)	NC score	0.034245 (rank : 384)
Query Neighborhood Hits	400	Target Neighborhood Hits	139	Shared Neighborhood Hits	23
SwissProt Accessions	Q9HCE9	Gene names	TMEM16H, KIAA1623
Domain Architecture	No domain graphic available
Description	Transmembrane protein 16H.

TXK_HUMAN
θ value	2.36792 (rank : 228)	NC score	0.062204 (rank : 214)
Query Neighborhood Hits	400	Target Neighborhood Hits	971	Shared Neighborhood Hits	87
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

ZIM10_MOUSE
θ value	2.36792 (rank : 229)	NC score	0.060692 (rank : 231)
Query Neighborhood Hits	400	Target Neighborhood Hits	430	Shared Neighborhood Hits	77
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

BAT4_MOUSE
θ value	3.0926 (rank : 230)	NC score	0.022251 (rank : 447)
Query Neighborhood Hits	400	Target Neighborhood Hits	171	Shared Neighborhood Hits	13
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

CLCN1_HUMAN
θ value	3.0926 (rank : 231)	NC score	0.012876 (rank : 500)
Query Neighborhood Hits	400	Target Neighborhood Hits	89	Shared Neighborhood Hits	11
SwissProt Accessions	P35523	Gene names	CLCN1, CLC1
Domain Architecture
Description	Chloride channel protein, skeletal muscle (Chloride channel protein 1) (ClC-1).

CO3A1_MOUSE
θ value	3.0926 (rank : 232)	NC score	0.040495 (rank : 364)
Query Neighborhood Hits	400	Target Neighborhood Hits	466	Shared Neighborhood Hits	70
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

EFS_HUMAN
θ value	3.0926 (rank : 233)	NC score	0.057597 (rank : 264)
Query Neighborhood Hits	400	Target Neighborhood Hits	348	Shared Neighborhood Hits	76
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

EP300_HUMAN
θ value	3.0926 (rank : 234)	NC score	0.100311 (rank : 61)
Query Neighborhood Hits	400	Target Neighborhood Hits	821	Shared Neighborhood Hits	127
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

FA47B_HUMAN
θ value	3.0926 (rank : 235)	NC score	0.053209 (rank : 305)
Query Neighborhood Hits	400	Target Neighborhood Hits	431	Shared Neighborhood Hits	62
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

FER_HUMAN
θ value	3.0926 (rank : 236)	NC score	0.048425 (rank : 334)
Query Neighborhood Hits	400	Target Neighborhood Hits	1278	Shared Neighborhood Hits	93
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

FOG1_MOUSE
θ value	3.0926 (rank : 237)	NC score	0.021410 (rank : 450)
Query Neighborhood Hits	400	Target Neighborhood Hits	1237	Shared Neighborhood Hits	106
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

GRB10_HUMAN
θ value	3.0926 (rank : 238)	NC score	0.086067 (rank : 88)
Query Neighborhood Hits	400	Target Neighborhood Hits	147	Shared Neighborhood Hits	67
SwissProt Accessions	Q13322, O00427, O00701, O75222, Q92606, Q92907, Q92948	Gene names	GRB10, GRBIR, KIAA0207
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein) (Insulin receptor-binding protein GRB-IR).

HXB3_HUMAN
θ value	3.0926 (rank : 239)	NC score	0.020582 (rank : 457)
Query Neighborhood Hits	400	Target Neighborhood Hits	559	Shared Neighborhood Hits	51
SwissProt Accessions	P14651, O95615, P17484	Gene names	HOXB3, HOX2G
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2G) (Hox-2.7).

IL2RB_MOUSE
θ value	3.0926 (rank : 240)	NC score	0.020937 (rank : 455)
Query Neighborhood Hits	400	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	P16297, Q3TZT2	Gene names	Il2rb
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).

ITK_HUMAN
θ value	3.0926 (rank : 241)	NC score	0.054915 (rank : 288)
Query Neighborhood Hits	400	Target Neighborhood Hits	1016	Shared Neighborhood Hits	85
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

NCK1_HUMAN
θ value	3.0926 (rank : 242)	NC score	0.105911 (rank : 50)
Query Neighborhood Hits	400	Target Neighborhood Hits	312	Shared Neighborhood Hits	79
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

NELF_MOUSE
θ value	3.0926 (rank : 243)	NC score	0.022918 (rank : 442)
Query Neighborhood Hits	400	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q99NF2, Q8BPT0, Q8C9R5, Q9DBF4, Q9ERZ1	Gene names	Nelf, Jac
Domain Architecture	No domain graphic available
Description	Nasal embryonic luteinizing hormone-releasing hormone factor (Nasal embryonic LHRH factor) (Juxtasynaptic attractor of caldendrin on dendritic boutons protein) (Jacob protein).

NKX26_MOUSE
θ value	3.0926 (rank : 244)	NC score	0.011135 (rank : 508)
Query Neighborhood Hits	400	Target Neighborhood Hits	343	Shared Neighborhood Hits	17
SwissProt Accessions	P43688	Gene names	Nkx2-6, Nkx-2.6, Nkx2f
Domain Architecture
Description	Homeobox protein Nkx-2.6 (Homeobox protein NK-2 homolog F).

NPAS4_HUMAN
θ value	3.0926 (rank : 245)	NC score	0.029591 (rank : 408)
Query Neighborhood Hits	400	Target Neighborhood Hits	214	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

NSD1_MOUSE
θ value	3.0926 (rank : 246)	NC score	0.036847 (rank : 371)
Query Neighborhood Hits	400	Target Neighborhood Hits	472	Shared Neighborhood Hits	49
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

NUMA1_HUMAN
θ value	3.0926 (rank : 247)	NC score	0.009383 (rank : 521)
Query Neighborhood Hits	400	Target Neighborhood Hits	1523	Shared Neighborhood Hits	45
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

NUP62_HUMAN
θ value	3.0926 (rank : 248)	NC score	0.036473 (rank : 373)
Query Neighborhood Hits	400	Target Neighborhood Hits	195	Shared Neighborhood Hits	17
SwissProt Accessions	P37198, Q503A4, Q96C43, Q9NSL1	Gene names	NUP62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

PCD12_MOUSE
θ value	3.0926 (rank : 249)	NC score	0.024293 (rank : 437)
Query Neighborhood Hits	400	Target Neighborhood Hits	199	Shared Neighborhood Hits	15
SwissProt Accessions	O55134	Gene names	Pcdh12
Domain Architecture
Description	Protocadherin-12 precursor (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cadherin-2) (VE-cad-2).

PML_HUMAN
θ value	3.0926 (rank : 250)	NC score	0.025496 (rank : 435)
Query Neighborhood Hits	400	Target Neighborhood Hits	248	Shared Neighborhood Hits	19
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

PSMF1_MOUSE
θ value	3.0926 (rank : 251)	NC score	0.025566 (rank : 433)
Query Neighborhood Hits	400	Target Neighborhood Hits	85	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BHL8, Q8C0G9	Gene names	Psmf1
Domain Architecture	No domain graphic available
Description	Proteasome inhibitor PI31 subunit.

PVRL2_HUMAN
θ value	3.0926 (rank : 252)	NC score	0.013013 (rank : 499)
Query Neighborhood Hits	400	Target Neighborhood Hits	185	Shared Neighborhood Hits	5
SwissProt Accessions	Q92692, O75455, Q96J29	Gene names	PVRL2, HVEB, PRR2
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Herpes virus entry mediator B) (HveB) (Nectin-2) (CD112 antigen).

QSCN6_HUMAN
θ value	3.0926 (rank : 253)	NC score	0.016164 (rank : 474)
Query Neighborhood Hits	400	Target Neighborhood Hits	98	Shared Neighborhood Hits	12
SwissProt Accessions	O00391, Q59G29, Q5T2X0, Q8TDL6, Q8WVP4	Gene names	QSCN6, QSOX1
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 1 precursor (EC 1.8.3.2) (Quiescin Q6) (hQSOX).

RBM15_HUMAN
θ value	3.0926 (rank : 254)	NC score	0.026998 (rank : 423)
Query Neighborhood Hits	400	Target Neighborhood Hits	309	Shared Neighborhood Hits	24
SwissProt Accessions	Q96T37, Q5D058, Q96PE4, Q96SC5, Q96SC6, Q96SC9, Q96SD0, Q96T38, Q9BRA5, Q9H6R8, Q9H9Y0	Gene names	RBM15, OTT
Domain Architecture
Description	Putative RNA-binding protein 15 (RNA-binding motif protein 15) (One- twenty two protein).

SSBP4_HUMAN
θ value	3.0926 (rank : 255)	NC score	0.051288 (rank : 319)
Query Neighborhood Hits	400	Target Neighborhood Hits	753	Shared Neighborhood Hits	101
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

TFG_HUMAN
θ value	3.0926 (rank : 256)	NC score	0.076668 (rank : 127)
Query Neighborhood Hits	400	Target Neighborhood Hits	122	Shared Neighborhood Hits	37
SwissProt Accessions	Q92734, Q15656	Gene names	TFG
Domain Architecture
Description	Protein TFG (TRK-fused gene protein).

TSH3_MOUSE
θ value	3.0926 (rank : 257)	NC score	0.014267 (rank : 489)
Query Neighborhood Hits	400	Target Neighborhood Hits	590	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CGV9, Q5DTX4	Gene names	Tshz3, Kiaa1474, Tsh3, Zfp537, Znf537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

TTBK2_HUMAN
θ value	3.0926 (rank : 258)	NC score	0.047088 (rank : 343)
Query Neighborhood Hits	400	Target Neighborhood Hits	822	Shared Neighborhood Hits	54
SwissProt Accessions	Q6IQ55, O94932, Q6ZN52, Q8IVV1	Gene names	TTBK2, KIAA0847
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2 (EC 2.7.11.1).

TTBK2_MOUSE
θ value	3.0926 (rank : 259)	NC score	0.047161 (rank : 341)
Query Neighborhood Hits	400	Target Neighborhood Hits	811	Shared Neighborhood Hits	50
SwissProt Accessions	Q3UVR3, Q3TSR6, Q3UFW0, Q571D1, Q8BKA4, Q924U8	Gene names	Ttbk2, Kiaa0847, Ttbk1
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2.

AFF3_HUMAN
θ value	4.03905 (rank : 260)	NC score	0.022527 (rank : 446)
Query Neighborhood Hits	400	Target Neighborhood Hits	190	Shared Neighborhood Hits	23
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

BCL9_HUMAN
θ value	4.03905 (rank : 261)	NC score	0.077385 (rank : 120)
Query Neighborhood Hits	400	Target Neighborhood Hits	1008	Shared Neighborhood Hits	135
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BTK_MOUSE
θ value	4.03905 (rank : 262)	NC score	0.061939 (rank : 219)
Query Neighborhood Hits	400	Target Neighborhood Hits	1017	Shared Neighborhood Hits	85
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

CD248_HUMAN
θ value	4.03905 (rank : 263)	NC score	0.025550 (rank : 434)
Query Neighborhood Hits	400	Target Neighborhood Hits	679	Shared Neighborhood Hits	62
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CDX4_HUMAN
θ value	4.03905 (rank : 264)	NC score	0.010575 (rank : 512)
Query Neighborhood Hits	400	Target Neighborhood Hits	366	Shared Neighborhood Hits	19
SwissProt Accessions	O14627, Q5JS20	Gene names	CDX4
Domain Architecture
Description	Homeobox protein CDX-4 (Caudal-type homeobox protein 4).

CSKI1_HUMAN
θ value	4.03905 (rank : 265)	NC score	0.034786 (rank : 379)
Query Neighborhood Hits	400	Target Neighborhood Hits	997	Shared Neighborhood Hits	110
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

DBNL_MOUSE
θ value	4.03905 (rank : 266)	NC score	0.033948 (rank : 385)
Query Neighborhood Hits	400	Target Neighborhood Hits	306	Shared Neighborhood Hits	44
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

DSG1C_MOUSE
θ value	4.03905 (rank : 267)	NC score	0.014873 (rank : 485)
Query Neighborhood Hits	400	Target Neighborhood Hits	156	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TSF0, Q7TQ61	Gene names	Dsg1c, Dsg6
Domain Architecture	No domain graphic available
Description	Desmoglein-1 gamma precursor (Dsg1-gamma) (Desmoglein-6).

GGA1_HUMAN
θ value	4.03905 (rank : 268)	NC score	0.016937 (rank : 471)
Query Neighborhood Hits	400	Target Neighborhood Hits	169	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

GP124_MOUSE
θ value	4.03905 (rank : 269)	NC score	0.009887 (rank : 519)
Query Neighborhood Hits	400	Target Neighborhood Hits	423	Shared Neighborhood Hits	24
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GRB2_HUMAN
θ value	4.03905 (rank : 270)	NC score	0.113858 (rank : 34)
Query Neighborhood Hits	400	Target Neighborhood Hits	310	Shared Neighborhood Hits	82
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	4.03905 (rank : 271)	NC score	0.113799 (rank : 35)
Query Neighborhood Hits	400	Target Neighborhood Hits	312	Shared Neighborhood Hits	82
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

HCK_HUMAN
θ value	4.03905 (rank : 272)	NC score	0.059836 (rank : 240)
Query Neighborhood Hits	400	Target Neighborhood Hits	1035	Shared Neighborhood Hits	88
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

ITK_MOUSE
θ value	4.03905 (rank : 273)	NC score	0.054808 (rank : 290)
Query Neighborhood Hits	400	Target Neighborhood Hits	985	Shared Neighborhood Hits	82
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

LNK_MOUSE
θ value	4.03905 (rank : 274)	NC score	0.093988 (rank : 74)
Query Neighborhood Hits	400	Target Neighborhood Hits	132	Shared Neighborhood Hits	63
SwissProt Accessions	O09039	Gene names	Lnk
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

LYN_MOUSE
θ value	4.03905 (rank : 275)	NC score	0.061427 (rank : 224)
Query Neighborhood Hits	400	Target Neighborhood Hits	1023	Shared Neighborhood Hits	90
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

MATK_MOUSE
θ value	4.03905 (rank : 276)	NC score	0.058612 (rank : 256)
Query Neighborhood Hits	400	Target Neighborhood Hits	952	Shared Neighborhood Hits	88
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

MCR_MOUSE
θ value	4.03905 (rank : 277)	NC score	0.010202 (rank : 515)
Query Neighborhood Hits	400	Target Neighborhood Hits	162	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

PLXB1_HUMAN
θ value	4.03905 (rank : 278)	NC score	0.019551 (rank : 461)
Query Neighborhood Hits	400	Target Neighborhood Hits	360	Shared Neighborhood Hits	46
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

PUM1_MOUSE
θ value	4.03905 (rank : 279)	NC score	0.015313 (rank : 482)
Query Neighborhood Hits	400	Target Neighborhood Hits	47	Shared Neighborhood Hits	9
SwissProt Accessions	Q80U78, Q80X96, Q80YU8, Q8BPV7, Q9EPU6	Gene names	Pum1, Kiaa0099
Domain Architecture
Description	Pumilio homolog 1.

RAI1_MOUSE
θ value	4.03905 (rank : 280)	NC score	0.040586 (rank : 362)
Query Neighborhood Hits	400	Target Neighborhood Hits	344	Shared Neighborhood Hits	54
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RBM14_HUMAN
θ value	4.03905 (rank : 281)	NC score	0.016709 (rank : 472)
Query Neighborhood Hits	400	Target Neighborhood Hits	213	Shared Neighborhood Hits	17
SwissProt Accessions	Q96PK6, O75932, Q53GV1, Q68DQ9, Q96PK5	Gene names	RBM14, SIP
Domain Architecture	No domain graphic available
Description	RNA-binding protein 14 (RNA-binding motif protein 14) (RRM-containing coactivator activator/modulator) (Synaptotagmin-interacting protein) (SYT-interacting protein).

RNPS1_HUMAN
θ value	4.03905 (rank : 282)	NC score	0.028634 (rank : 415)
Query Neighborhood Hits	400	Target Neighborhood Hits	285	Shared Neighborhood Hits	20
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
θ value	4.03905 (rank : 283)	NC score	0.028634 (rank : 416)
Query Neighborhood Hits	400	Target Neighborhood Hits	285	Shared Neighborhood Hits	20
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

RXRB_HUMAN
θ value	4.03905 (rank : 284)	NC score	0.019477 (rank : 462)
Query Neighborhood Hits	400	Target Neighborhood Hits	280	Shared Neighborhood Hits	52
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

RXRB_MOUSE
θ value	4.03905 (rank : 285)	NC score	0.016271 (rank : 473)
Query Neighborhood Hits	400	Target Neighborhood Hits	230	Shared Neighborhood Hits	44
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

SC24A_MOUSE
θ value	4.03905 (rank : 286)	NC score	0.057219 (rank : 270)
Query Neighborhood Hits	400	Target Neighborhood Hits	394	Shared Neighborhood Hits	59
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

SELPL_MOUSE
θ value	4.03905 (rank : 287)	NC score	0.071178 (rank : 159)
Query Neighborhood Hits	400	Target Neighborhood Hits	588	Shared Neighborhood Hits	78
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SH24A_MOUSE
θ value	4.03905 (rank : 288)	NC score	0.096381 (rank : 67)
Query Neighborhood Hits	400	Target Neighborhood Hits	326	Shared Neighborhood Hits	57
SwissProt Accessions	Q9D7V1	Gene names	Sh2d4a
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A.

SHC1_HUMAN
θ value	4.03905 (rank : 289)	NC score	0.079268 (rank : 114)
Query Neighborhood Hits	400	Target Neighborhood Hits	170	Shared Neighborhood Hits	71
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHC1_MOUSE
θ value	4.03905 (rank : 290)	NC score	0.080195 (rank : 110)
Query Neighborhood Hits	400	Target Neighborhood Hits	180	Shared Neighborhood Hits	72
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SIG10_HUMAN
θ value	4.03905 (rank : 291)	NC score	0.013038 (rank : 498)
Query Neighborhood Hits	400	Target Neighborhood Hits	363	Shared Neighborhood Hits	27
SwissProt Accessions	Q96LC7, Q6UXI8, Q96G54, Q96LC8	Gene names	SIGLEC10, SLG2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 10 precursor (Siglec-10) (Siglec- like protein 2).

SMOO_HUMAN
θ value	4.03905 (rank : 292)	NC score	0.047439 (rank : 339)
Query Neighborhood Hits	400	Target Neighborhood Hits	391	Shared Neighborhood Hits	57
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

TB182_HUMAN
θ value	4.03905 (rank : 293)	NC score	0.077412 (rank : 119)
Query Neighborhood Hits	400	Target Neighborhood Hits	414	Shared Neighborhood Hits	71
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

TCPZ_HUMAN
θ value	4.03905 (rank : 294)	NC score	0.007407 (rank : 531)
Query Neighborhood Hits	400	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	P40227, Q75LP4, Q96S46	Gene names	CCT6A, CCT6, CCTZ
Domain Architecture
Description	T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) (CCT-zeta-1) (Tcp20) (HTR3) (Acute morphine dependence-related protein 2).

TP53B_MOUSE
θ value	4.03905 (rank : 295)	NC score	0.054082 (rank : 295)
Query Neighborhood Hits	400	Target Neighborhood Hits	644	Shared Neighborhood Hits	67
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TXK_MOUSE
θ value	4.03905 (rank : 296)	NC score	0.062149 (rank : 215)
Query Neighborhood Hits	400	Target Neighborhood Hits	980	Shared Neighborhood Hits	85
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

WDR33_HUMAN
θ value	4.03905 (rank : 297)	NC score	0.031911 (rank : 396)
Query Neighborhood Hits	400	Target Neighborhood Hits	638	Shared Neighborhood Hits	61
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

X3CL1_HUMAN
θ value	4.03905 (rank : 298)	NC score	0.027624 (rank : 418)
Query Neighborhood Hits	400	Target Neighborhood Hits	152	Shared Neighborhood Hits	22
SwissProt Accessions	P78423, O00672	Gene names	CX3CL1, A-152E5.2, FKN, NTT, SCYD1
Domain Architecture
Description	Fractalkine precursor (CX3CL1) (Neurotactin) (CX3C membrane-anchored chemokine) (Small inducible cytokine D1).

YES_HUMAN
θ value	4.03905 (rank : 299)	NC score	0.060259 (rank : 234)
Query Neighborhood Hits	400	Target Neighborhood Hits	1059	Shared Neighborhood Hits	87
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

YES_MOUSE
θ value	4.03905 (rank : 300)	NC score	0.060141 (rank : 237)
Query Neighborhood Hits	400	Target Neighborhood Hits	1052	Shared Neighborhood Hits	87
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

ZEP1_MOUSE
θ value	4.03905 (rank : 301)	NC score	0.013813 (rank : 493)
Query Neighborhood Hits	400	Target Neighborhood Hits	1063	Shared Neighborhood Hits	73
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

ACHA4_HUMAN
θ value	5.27518 (rank : 302)	NC score	0.007599 (rank : 529)
Query Neighborhood Hits	400	Target Neighborhood Hits	131	Shared Neighborhood Hits	15
SwissProt Accessions	P43681, Q4JGR7	Gene names	CHRNA4, NACRA4
Domain Architecture
Description	Neuronal acetylcholine receptor protein subunit alpha-4 precursor.

ANKS6_MOUSE
θ value	5.27518 (rank : 303)	NC score	0.011734 (rank : 505)
Query Neighborhood Hits	400	Target Neighborhood Hits	435	Shared Neighborhood Hits	29
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ASTL_HUMAN
θ value	5.27518 (rank : 304)	NC score	0.026595 (rank : 426)
Query Neighborhood Hits	400	Target Neighborhood Hits	252	Shared Neighborhood Hits	42
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

ATX7_HUMAN
θ value	5.27518 (rank : 305)	NC score	0.032890 (rank : 392)
Query Neighborhood Hits	400	Target Neighborhood Hits	351	Shared Neighborhood Hits	52
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

CEP35_HUMAN
θ value	5.27518 (rank : 306)	NC score	0.018323 (rank : 465)
Query Neighborhood Hits	400	Target Neighborhood Hits	811	Shared Neighborhood Hits	27
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

CHIN_MOUSE
θ value	5.27518 (rank : 307)	NC score	0.048593 (rank : 333)
Query Neighborhood Hits	400	Target Neighborhood Hits	229	Shared Neighborhood Hits	65
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIT1_HUMAN
θ value	5.27518 (rank : 308)	NC score	0.007702 (rank : 527)
Query Neighborhood Hits	400	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q13231, Q3ZAR1, Q6ISC2, Q9H3V8	Gene names	CHIT1
Domain Architecture
Description	Chitotriosidase-1 precursor (EC 3.2.1.14) (Chitinase-1).

CING_HUMAN
θ value	5.27518 (rank : 309)	NC score	0.007088 (rank : 532)
Query Neighborhood Hits	400	Target Neighborhood Hits	1275	Shared Neighborhood Hits	37
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CO039_HUMAN
θ value	5.27518 (rank : 310)	NC score	0.046584 (rank : 346)
Query Neighborhood Hits	400	Target Neighborhood Hits	264	Shared Neighborhood Hits	49
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

CRTC1_HUMAN
θ value	5.27518 (rank : 311)	NC score	0.061547 (rank : 223)
Query Neighborhood Hits	400	Target Neighborhood Hits	319	Shared Neighborhood Hits	76
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

DAPP1_MOUSE
θ value	5.27518 (rank : 312)	NC score	0.104468 (rank : 55)
Query Neighborhood Hits	400	Target Neighborhood Hits	225	Shared Neighborhood Hits	82
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

EVI1_HUMAN
θ value	5.27518 (rank : 313)	NC score	0.000355 (rank : 545)
Query Neighborhood Hits	400	Target Neighborhood Hits	924	Shared Neighborhood Hits	34
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.

GA2L1_MOUSE
θ value	5.27518 (rank : 314)	NC score	0.033455 (rank : 388)
Query Neighborhood Hits	400	Target Neighborhood Hits	114	Shared Neighborhood Hits	26
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

GRAP_HUMAN
θ value	5.27518 (rank : 315)	NC score	0.117007 (rank : 30)
Query Neighborhood Hits	400	Target Neighborhood Hits	307	Shared Neighborhood Hits	82
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

HCK_MOUSE
θ value	5.27518 (rank : 316)	NC score	0.059422 (rank : 247)
Query Neighborhood Hits	400	Target Neighborhood Hits	1029	Shared Neighborhood Hits	86
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

KS6C1_HUMAN
θ value	5.27518 (rank : 317)	NC score	0.017038 (rank : 470)
Query Neighborhood Hits	400	Target Neighborhood Hits	682	Shared Neighborhood Hits	31
SwissProt Accessions	Q96S38, Q8TDD3, Q9NSF4, Q9UL66	Gene names	RPS6KC1, RPK118
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein).

MAGE1_HUMAN
θ value	5.27518 (rank : 318)	NC score	0.080316 (rank : 109)
Query Neighborhood Hits	400	Target Neighborhood Hits	1389	Shared Neighborhood Hits	167
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MATK_HUMAN
θ value	5.27518 (rank : 319)	NC score	0.057384 (rank : 267)
Query Neighborhood Hits	400	Target Neighborhood Hits	954	Shared Neighborhood Hits	88
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

MTR1L_HUMAN
θ value	5.27518 (rank : 320)	NC score	0.002070 (rank : 542)
Query Neighborhood Hits	400	Target Neighborhood Hits	1180	Shared Neighborhood Hits	51
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

MUCDL_HUMAN
θ value	5.27518 (rank : 321)	NC score	0.068890 (rank : 169)
Query Neighborhood Hits	400	Target Neighborhood Hits	777	Shared Neighborhood Hits	109
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NFAC4_HUMAN
θ value	5.27518 (rank : 322)	NC score	0.018751 (rank : 463)
Query Neighborhood Hits	400	Target Neighborhood Hits	165	Shared Neighborhood Hits	24
SwissProt Accessions	Q14934	Gene names	NFATC4, NFAT3
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T cell transcription factor NFAT3) (NF-AT3).

PLAL1_HUMAN
θ value	5.27518 (rank : 323)	NC score	0.000340 (rank : 546)
Query Neighborhood Hits	400	Target Neighborhood Hits	728	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UM63	Gene names	PLAGL1
Domain Architecture	No domain graphic available
Description	Zinc finger protein PLAGL1 (Pleiomorphic adenoma-like protein 1).

PTN6_HUMAN
θ value	5.27518 (rank : 324)	NC score	0.055007 (rank : 286)
Query Neighborhood Hits	400	Target Neighborhood Hits	234	Shared Neighborhood Hits	74
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN6_MOUSE
θ value	5.27518 (rank : 325)	NC score	0.062882 (rank : 211)
Query Neighborhood Hits	400	Target Neighborhood Hits	225	Shared Neighborhood Hits	79
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

RAPH1_HUMAN
θ value	5.27518 (rank : 326)	NC score	0.083176 (rank : 99)
Query Neighborhood Hits	400	Target Neighborhood Hits	593	Shared Neighborhood Hits	90
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RBM14_MOUSE
θ value	5.27518 (rank : 327)	NC score	0.015152 (rank : 483)
Query Neighborhood Hits	400	Target Neighborhood Hits	217	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C2Q3, Q3TJB6, Q91Z21, Q9DBI6	Gene names	Rbm14
Domain Architecture	No domain graphic available
Description	RNA-binding protein 14 (RNA-binding motif protein 14).

RGS3_HUMAN
θ value	5.27518 (rank : 328)	NC score	0.064902 (rank : 194)
Query Neighborhood Hits	400	Target Neighborhood Hits	1375	Shared Neighborhood Hits	129
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SYNPO_MOUSE
θ value	5.27518 (rank : 329)	NC score	0.046242 (rank : 348)
Query Neighborhood Hits	400	Target Neighborhood Hits	242	Shared Neighborhood Hits	48
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

WASL_HUMAN
θ value	5.27518 (rank : 330)	NC score	0.070321 (rank : 163)
Query Neighborhood Hits	400	Target Neighborhood Hits	312	Shared Neighborhood Hits	66
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

ZCH14_MOUSE
θ value	5.27518 (rank : 331)	NC score	0.043728 (rank : 358)
Query Neighborhood Hits	400	Target Neighborhood Hits	109	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VIG0, Q80TX3, Q91VU4	Gene names	Zcchc14, Kiaa0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

ZIC1_HUMAN
θ value	5.27518 (rank : 332)	NC score	0.000672 (rank : 544)
Query Neighborhood Hits	400	Target Neighborhood Hits	710	Shared Neighborhood Hits	18
SwissProt Accessions	Q15915	Gene names	ZIC1, ZIC
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZIC 1 (Zinc finger protein of the cerebellum 1).

ADAM9_MOUSE
θ value	6.88961 (rank : 333)	NC score	0.004992 (rank : 538)
Query Neighborhood Hits	400	Target Neighborhood Hits	325	Shared Neighborhood Hits	27
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ANR50_HUMAN
θ value	6.88961 (rank : 334)	NC score	0.003999 (rank : 539)
Query Neighborhood Hits	400	Target Neighborhood Hits	361	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

BSN_HUMAN
θ value	6.88961 (rank : 335)	NC score	0.098915 (rank : 64)
Query Neighborhood Hits	400	Target Neighborhood Hits	1537	Shared Neighborhood Hits	160
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

BTBD7_HUMAN
θ value	6.88961 (rank : 336)	NC score	0.013377 (rank : 495)
Query Neighborhood Hits	400	Target Neighborhood Hits	176	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P203, Q69Z05, Q7Z308, Q86TS0, Q9HAA4, Q9NVM0	Gene names	BTBD7, KIAA1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

CECR6_MOUSE
θ value	6.88961 (rank : 337)	NC score	0.016083 (rank : 476)
Query Neighborhood Hits	400	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q99MX7	Gene names	Cecr6
Domain Architecture	No domain graphic available
Description	Cat eye syndrome critical region protein 6 homolog.

CO2_HUMAN
θ value	6.88961 (rank : 338)	NC score	0.002085 (rank : 541)
Query Neighborhood Hits	400	Target Neighborhood Hits	258	Shared Neighborhood Hits	6
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO8A2_MOUSE
θ value	6.88961 (rank : 339)	NC score	0.026367 (rank : 427)
Query Neighborhood Hits	400	Target Neighborhood Hits	273	Shared Neighborhood Hits	50
SwissProt Accessions	P25318, Q68ED0, Q6KAQ4, Q6P1C4	Gene names	Col8a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

COHA1_HUMAN
θ value	6.88961 (rank : 340)	NC score	0.044073 (rank : 357)
Query Neighborhood Hits	400	Target Neighborhood Hits	400	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

ETV5_MOUSE
θ value	6.88961 (rank : 341)	NC score	0.013136 (rank : 496)
Query Neighborhood Hits	400	Target Neighborhood Hits	328	Shared Neighborhood Hits	39
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

GA2L1_HUMAN
θ value	6.88961 (rank : 342)	NC score	0.034380 (rank : 382)
Query Neighborhood Hits	400	Target Neighborhood Hits	177	Shared Neighborhood Hits	42
SwissProt Accessions	Q99501, Q53EN7, Q92640, Q9BUY9	Gene names	GAS2L1, GAR22
Domain Architecture
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1) (GAS2-related protein on chromosome 22) (GAR22 protein).

GP132_MOUSE
θ value	6.88961 (rank : 343)	NC score	-0.001721 (rank : 550)
Query Neighborhood Hits	400	Target Neighborhood Hits	488	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z282, Q3U5A4	Gene names	Gpr132, G2a
Domain Architecture
Description	Probable G-protein coupled receptor 132 (G2 accumulation protein).

K1802_HUMAN
θ value	6.88961 (rank : 344)	NC score	0.060319 (rank : 232)
Query Neighborhood Hits	400	Target Neighborhood Hits	1378	Shared Neighborhood Hits	122
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LYN_HUMAN
θ value	6.88961 (rank : 345)	NC score	0.059796 (rank : 241)
Query Neighborhood Hits	400	Target Neighborhood Hits	1022	Shared Neighborhood Hits	90
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

MAML1_HUMAN
θ value	6.88961 (rank : 346)	NC score	0.054445 (rank : 291)
Query Neighborhood Hits	400	Target Neighborhood Hits	228	Shared Neighborhood Hits	41
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

MARCS_MOUSE
θ value	6.88961 (rank : 347)	NC score	0.066913 (rank : 184)
Query Neighborhood Hits	400	Target Neighborhood Hits	227	Shared Neighborhood Hits	38
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MUC5B_HUMAN
θ value	6.88961 (rank : 348)	NC score	0.043053 (rank : 359)
Query Neighborhood Hits	400	Target Neighborhood Hits	1020	Shared Neighborhood Hits	91
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NRDC_MOUSE
θ value	6.88961 (rank : 349)	NC score	0.009280 (rank : 522)
Query Neighborhood Hits	400	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHG1	Gene names	Nrd1
Domain Architecture
Description	Nardilysin precursor (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C).

NRG2_HUMAN
θ value	6.88961 (rank : 350)	NC score	0.013091 (rank : 497)
Query Neighborhood Hits	400	Target Neighborhood Hits	419	Shared Neighborhood Hits	20
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

P3C2A_HUMAN
θ value	6.88961 (rank : 351)	NC score	0.015491 (rank : 480)
Query Neighborhood Hits	400	Target Neighborhood Hits	188	Shared Neighborhood Hits	17
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

RARA_HUMAN
θ value	6.88961 (rank : 352)	NC score	0.005447 (rank : 535)
Query Neighborhood Hits	400	Target Neighborhood Hits	118	Shared Neighborhood Hits	8
SwissProt Accessions	P10276, P78456, Q13440, Q13441, Q9NQS0	Gene names	RARA, NR1B1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARA_MOUSE
θ value	6.88961 (rank : 353)	NC score	0.005370 (rank : 536)
Query Neighborhood Hits	400	Target Neighborhood Hits	113	Shared Neighborhood Hits	6
SwissProt Accessions	P11416, P22603	Gene names	Rara, Nr1b1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

REPS1_MOUSE
θ value	6.88961 (rank : 354)	NC score	0.023720 (rank : 441)
Query Neighborhood Hits	400	Target Neighborhood Hits	204	Shared Neighborhood Hits	24
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

SENP1_MOUSE
θ value	6.88961 (rank : 355)	NC score	0.010016 (rank : 517)
Query Neighborhood Hits	400	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	P59110	Gene names	Senp1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

SFTPD_MOUSE
θ value	6.88961 (rank : 356)	NC score	0.020291 (rank : 458)
Query Neighborhood Hits	400	Target Neighborhood Hits	217	Shared Neighborhood Hits	29
SwissProt Accessions	P50404	Gene names	Sftpd, Sftp4
Domain Architecture
Description	Pulmonary surfactant-associated protein D precursor (SP-D) (PSP-D).

SOCS2_HUMAN
θ value	6.88961 (rank : 357)	NC score	0.072930 (rank : 150)
Query Neighborhood Hits	400	Target Neighborhood Hits	104	Shared Neighborhood Hits	51
SwissProt Accessions	O14508, O14542, O95102, Q9UKS5	Gene names	SOCS2, CIS2, SSI2, STATI2
Domain Architecture
Description	Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2) (CIS-2) (STAT-induced STAT inhibitor 2) (SSI-2).

SYN3_MOUSE
θ value	6.88961 (rank : 358)	NC score	0.053096 (rank : 308)
Query Neighborhood Hits	400	Target Neighborhood Hits	200	Shared Neighborhood Hits	46
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

TFE2_HUMAN
θ value	6.88961 (rank : 359)	NC score	0.018232 (rank : 467)
Query Neighborhood Hits	400	Target Neighborhood Hits	161	Shared Neighborhood Hits	20
SwissProt Accessions	P15923, P15883, Q14208, Q14635, Q14636, Q9UPI9	Gene names	TCF3, E2A, ITF1
Domain Architecture
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Immunoglobulin transcription factor 1) (Transcription factor ITF-1) (Kappa-E2-binding factor).

TNFC_MOUSE
θ value	6.88961 (rank : 360)	NC score	0.014938 (rank : 484)
Query Neighborhood Hits	400	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	P41155	Gene names	Ltb, Tnfc, Tnfsf3
Domain Architecture
Description	Lymphotoxin-beta (LT-beta) (Tumor necrosis factor C) (TNF-C) (Tumor necrosis factor ligand superfamily member 3).

YAP1_HUMAN
θ value	6.88961 (rank : 361)	NC score	0.027168 (rank : 421)
Query Neighborhood Hits	400	Target Neighborhood Hits	173	Shared Neighborhood Hits	35
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

ZN167_HUMAN
θ value	6.88961 (rank : 362)	NC score	-0.003202 (rank : 551)
Query Neighborhood Hits	400	Target Neighborhood Hits	784	Shared Neighborhood Hits	22
SwissProt Accessions	Q9P0L1, Q6WL09, Q96FQ2	Gene names	ZNF167, ZNF448, ZNF64
Domain Architecture	No domain graphic available
Description	Zinc finger protein 167 (Zinc finger protein 64) (Zinc finger protein 448) (ZFP).

ZNF24_MOUSE
θ value	6.88961 (rank : 363)	NC score	-0.001552 (rank : 549)
Query Neighborhood Hits	400	Target Neighborhood Hits	717	Shared Neighborhood Hits	18
SwissProt Accessions	Q91VN1, Q9WUQ0	Gene names	Znf24, Zfp191
Domain Architecture
Description	Zinc finger protein 24 (Zinc finger protein 191) (Zfp-191) (Zinc finger protein ZF-12).

AATK_HUMAN
θ value	8.99809 (rank : 364)	NC score	0.044355 (rank : 355)
Query Neighborhood Hits	400	Target Neighborhood Hits	1243	Shared Neighborhood Hits	112
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

ADA12_MOUSE
θ value	8.99809 (rank : 365)	NC score	0.008279 (rank : 526)
Query Neighborhood Hits	400	Target Neighborhood Hits	474	Shared Neighborhood Hits	46
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADDB_MOUSE
θ value	8.99809 (rank : 366)	NC score	0.022664 (rank : 445)
Query Neighborhood Hits	400	Target Neighborhood Hits	574	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

ATBF1_MOUSE
θ value	8.99809 (rank : 367)	NC score	0.021066 (rank : 453)
Query Neighborhood Hits	400	Target Neighborhood Hits	1841	Shared Neighborhood Hits	125
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

BCAR3_HUMAN
θ value	8.99809 (rank : 368)	NC score	0.056241 (rank : 276)
Query Neighborhood Hits	400	Target Neighborhood Hits	129	Shared Neighborhood Hits	55
SwissProt Accessions	O75815, Q6UW40, Q9BR50	Gene names	BCAR3, NSP2, SH2D3B
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (SH2 domain- containing protein 3B) (Novel SH2-containing protein 2).

BRSK1_HUMAN
θ value	8.99809 (rank : 369)	NC score	0.029522 (rank : 409)
Query Neighborhood Hits	400	Target Neighborhood Hits	942	Shared Neighborhood Hits	67
SwissProt Accessions	Q8TDC3, Q5J5B5, Q8NDD0, Q8NDR4, Q8TDC2, Q96AV4, Q96JL4	Gene names	BRSK1, KIAA1811, SAD1
Domain Architecture
Description	BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1 kinase) (SAD1A).

CGRE1_HUMAN
θ value	8.99809 (rank : 370)	NC score	0.027288 (rank : 420)
Query Neighborhood Hits	400	Target Neighborhood Hits	354	Shared Neighborhood Hits	31
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

CJ006_MOUSE
θ value	8.99809 (rank : 371)	NC score	0.011569 (rank : 506)
Query Neighborhood Hits	400	Target Neighborhood Hits	141	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P9P0, Q8C041, Q8C0J5	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf6 homolog.

CMGA_MOUSE
θ value	8.99809 (rank : 372)	NC score	0.021289 (rank : 452)
Query Neighborhood Hits	400	Target Neighborhood Hits	172	Shared Neighborhood Hits	16
SwissProt Accessions	P26339	Gene names	Chga
Domain Architecture
Description	Chromogranin A precursor (CgA) [Contains: Pancreastatin; Beta-granin; WE-14].

CO002_HUMAN
θ value	8.99809 (rank : 373)	NC score	0.046857 (rank : 344)
Query Neighborhood Hits	400	Target Neighborhood Hits	387	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

CO4A1_MOUSE
θ value	8.99809 (rank : 374)	NC score	0.032644 (rank : 393)
Query Neighborhood Hits	400	Target Neighborhood Hits	450	Shared Neighborhood Hits	72
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

CTTB2_HUMAN
θ value	8.99809 (rank : 375)	NC score	0.010731 (rank : 511)
Query Neighborhood Hits	400	Target Neighborhood Hits	1061	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

DAPP1_HUMAN
θ value	8.99809 (rank : 376)	NC score	0.102432 (rank : 56)
Query Neighborhood Hits	400	Target Neighborhood Hits	227	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

ELN_HUMAN
θ value	8.99809 (rank : 377)	NC score	0.037307 (rank : 369)
Query Neighborhood Hits	400	Target Neighborhood Hits	85	Shared Neighborhood Hits	20
SwissProt Accessions	P15502, O15336, O15337, Q14233, Q14234, Q14235, Q14238, Q6P0L4, Q6ZWJ6, Q75MU5, Q7Z316, Q7Z3F5, Q9UMF5	Gene names	ELN
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

ES8L2_MOUSE
θ value	8.99809 (rank : 378)	NC score	0.032137 (rank : 395)
Query Neighborhood Hits	400	Target Neighborhood Hits	169	Shared Neighborhood Hits	42
SwissProt Accessions	Q99K30, Q91VT7	Gene names	Eps8l2, Eps8r2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

GLE1_MOUSE
θ value	8.99809 (rank : 379)	NC score	0.011750 (rank : 504)
Query Neighborhood Hits	400	Target Neighborhood Hits	504	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

HLXB9_MOUSE
θ value	8.99809 (rank : 380)	NC score	0.008546 (rank : 525)
Query Neighborhood Hits	400	Target Neighborhood Hits	354	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QZW9	Gene names	Hlxb9
Domain Architecture
Description	Homeobox protein HB9.

HMCN1_HUMAN
θ value	8.99809 (rank : 381)	NC score	-0.000069 (rank : 548)
Query Neighborhood Hits	400	Target Neighborhood Hits	983	Shared Neighborhood Hits	20
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

IMMT_MOUSE
θ value	8.99809 (rank : 382)	NC score	0.010408 (rank : 513)
Query Neighborhood Hits	400	Target Neighborhood Hits	326	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CAQ8, Q66JS4, Q7TNE2, Q8C7V1, Q8CCI0, Q8CDA8, Q9D9F6	Gene names	Immt
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin).

NCK2_HUMAN
θ value	8.99809 (rank : 383)	NC score	0.107680 (rank : 47)
Query Neighborhood Hits	400	Target Neighborhood Hits	310	Shared Neighborhood Hits	87
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

OGFR_MOUSE
θ value	8.99809 (rank : 384)	NC score	0.055824 (rank : 277)
Query Neighborhood Hits	400	Target Neighborhood Hits	584	Shared Neighborhood Hits	63
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

OTX2_HUMAN
θ value	8.99809 (rank : 385)	NC score	0.010368 (rank : 514)
Query Neighborhood Hits	400	Target Neighborhood Hits	341	Shared Neighborhood Hits	18
SwissProt Accessions	P32243, Q6GTV3, Q9HAW3, Q9P2R1	Gene names	OTX2
Domain Architecture
Description	Homeobox protein OTX2.

PI5PA_HUMAN
θ value	8.99809 (rank : 386)	NC score	0.059476 (rank : 245)
Query Neighborhood Hits	400	Target Neighborhood Hits	749	Shared Neighborhood Hits	111
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PKP4_MOUSE
θ value	8.99809 (rank : 387)	NC score	0.007691 (rank : 528)
Query Neighborhood Hits	400	Target Neighborhood Hits	129	Shared Neighborhood Hits	15
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

PO6F2_HUMAN
θ value	8.99809 (rank : 388)	NC score	0.032977 (rank : 390)
Query Neighborhood Hits	400	Target Neighborhood Hits	618	Shared Neighborhood Hits	77
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

PODXL_MOUSE
θ value	8.99809 (rank : 389)	NC score	0.031437 (rank : 399)
Query Neighborhood Hits	400	Target Neighborhood Hits	130	Shared Neighborhood Hits	26
SwissProt Accessions	Q9R0M4, Q9ESZ1	Gene names	Podxl, Pclp1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

PSD4_HUMAN
θ value	8.99809 (rank : 390)	NC score	0.017670 (rank : 468)
Query Neighborhood Hits	400	Target Neighborhood Hits	178	Shared Neighborhood Hits	27
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

REV1_HUMAN
θ value	8.99809 (rank : 391)	NC score	0.010940 (rank : 510)
Query Neighborhood Hits	400	Target Neighborhood Hits	56	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UBZ9, O95941, Q9C0J4, Q9NUP2	Gene names	REV1L, REV1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase) (Alpha integrin-binding protein 80) (AIBP80).

RHG25_MOUSE
θ value	8.99809 (rank : 392)	NC score	0.020237 (rank : 459)
Query Neighborhood Hits	400	Target Neighborhood Hits	492	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RIMB2_MOUSE
θ value	8.99809 (rank : 393)	NC score	0.018309 (rank : 466)
Query Neighborhood Hits	400	Target Neighborhood Hits	246	Shared Neighborhood Hits	28
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

SOX30_MOUSE
θ value	8.99809 (rank : 394)	NC score	0.022160 (rank : 448)
Query Neighborhood Hits	400	Target Neighborhood Hits	374	Shared Neighborhood Hits	48
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

SYTL5_HUMAN
θ value	8.99809 (rank : 395)	NC score	0.012388 (rank : 501)
Query Neighborhood Hits	400	Target Neighborhood Hits	237	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

TNR6A_HUMAN
θ value	8.99809 (rank : 396)	NC score	0.042961 (rank : 360)
Query Neighborhood Hits	400	Target Neighborhood Hits	343	Shared Neighborhood Hits	45
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

TULP4_HUMAN
θ value	8.99809 (rank : 397)	NC score	0.024126 (rank : 438)
Query Neighborhood Hits	400	Target Neighborhood Hits	426	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

UBAP1_HUMAN
θ value	8.99809 (rank : 398)	NC score	0.010977 (rank : 509)
Query Neighborhood Hits	400	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZ09, Q4V759, Q5T7B3, Q6FI75, Q8NC52, Q8NCG6, Q8NCH9	Gene names	UBAP1
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 1 (UBAP).

UBP10_MOUSE
θ value	8.99809 (rank : 399)	NC score	0.010044 (rank : 516)
Query Neighborhood Hits	400	Target Neighborhood Hits	150	Shared Neighborhood Hits	13
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

ZIC1_MOUSE
θ value	8.99809 (rank : 400)	NC score	0.000238 (rank : 547)
Query Neighborhood Hits	400	Target Neighborhood Hits	716	Shared Neighborhood Hits	20
SwissProt Accessions	P46684	Gene names	Zic1, Zic
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZIC 1 (Zinc finger protein of the cerebellum 1).

3BP1_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.051970 (rank : 314)
Query Neighborhood Hits	400	Target Neighborhood Hits	376	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

AAK1_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.063820 (rank : 205)
Query Neighborhood Hits	400	Target Neighborhood Hits	1077	Shared Neighborhood Hits	105
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

AAK1_MOUSE
θ value	θ > 10 (rank : 403)	NC score	0.062605 (rank : 212)
Query Neighborhood Hits	400	Target Neighborhood Hits	1051	Shared Neighborhood Hits	100
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

AFF1_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.051451 (rank : 318)
Query Neighborhood Hits	400	Target Neighborhood Hits	506	Shared Neighborhood Hits	72
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

ALEX_MOUSE
θ value	θ > 10 (rank : 405)	NC score	0.068631 (rank : 171)
Query Neighborhood Hits	400	Target Neighborhood Hits	197	Shared Neighborhood Hits	50
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

APS_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.074477 (rank : 143)
Query Neighborhood Hits	400	Target Neighborhood Hits	162	Shared Neighborhood Hits	68
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

APS_MOUSE
θ value	θ > 10 (rank : 407)	NC score	0.058750 (rank : 254)
Query Neighborhood Hits	400	Target Neighborhood Hits	134	Shared Neighborhood Hits	56
SwissProt Accessions	Q9JID9, O88936	Gene names	Aps
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

ATN1_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.084045 (rank : 96)
Query Neighborhood Hits	400	Target Neighborhood Hits	676	Shared Neighborhood Hits	103
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

ATX2L_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.074815 (rank : 140)
Query Neighborhood Hits	400	Target Neighborhood Hits	443	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

ATX2_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.072162 (rank : 154)
Query Neighborhood Hits	400	Target Neighborhood Hits	375	Shared Neighborhood Hits	68
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

ATX2_MOUSE
θ value	θ > 10 (rank : 411)	NC score	0.068257 (rank : 173)
Query Neighborhood Hits	400	Target Neighborhood Hits	445	Shared Neighborhood Hits	87
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

BASP_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.064052 (rank : 204)
Query Neighborhood Hits	400	Target Neighborhood Hits	321	Shared Neighborhood Hits	41
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BASP_MOUSE
θ value	θ > 10 (rank : 413)	NC score	0.074306 (rank : 144)
Query Neighborhood Hits	400	Target Neighborhood Hits	260	Shared Neighborhood Hits	44
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BAT2_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.085749 (rank : 89)
Query Neighborhood Hits	400	Target Neighborhood Hits	931	Shared Neighborhood Hits	131
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BCAR1_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.052741 (rank : 310)
Query Neighborhood Hits	400	Target Neighborhood Hits	554	Shared Neighborhood Hits	107
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BCAR3_MOUSE
θ value	θ > 10 (rank : 416)	NC score	0.053140 (rank : 307)
Query Neighborhood Hits	400	Target Neighborhood Hits	127	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QZK2, Q3TNC9, Q3UP10	Gene names	Bcar3, And34
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (p130Cas-binding protein AND-34).

BCL9_MOUSE
θ value	θ > 10 (rank : 417)	NC score	0.069494 (rank : 166)
Query Neighborhood Hits	400	Target Neighborhood Hits	770	Shared Neighborhood Hits	110
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

BLK_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.057233 (rank : 269)
Query Neighborhood Hits	400	Target Neighborhood Hits	994	Shared Neighborhood Hits	81
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BLNK_MOUSE
θ value	θ > 10 (rank : 419)	NC score	0.059283 (rank : 248)
Query Neighborhood Hits	400	Target Neighborhood Hits	296	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

BMP2K_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.052345 (rank : 313)
Query Neighborhood Hits	400	Target Neighborhood Hits	867	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NSY1, O94791, Q8IYF2, Q8N2G7, Q8NHG9, Q9NTG8	Gene names	BMP2K, BIKE
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

BMP2K_MOUSE
θ value	θ > 10 (rank : 421)	NC score	0.050197 (rank : 327)
Query Neighborhood Hits	400	Target Neighborhood Hits	874	Shared Neighborhood Hits	48
SwissProt Accessions	Q91Z96, Q8C8L7	Gene names	Bmp2k, Bike
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

CCNK_MOUSE
θ value	θ > 10 (rank : 422)	NC score	0.059762 (rank : 243)
Query Neighborhood Hits	400	Target Neighborhood Hits	350	Shared Neighborhood Hits	70
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CDN1C_HUMAN
θ value	θ > 10 (rank : 423)	NC score	0.058080 (rank : 261)
Query Neighborhood Hits	400	Target Neighborhood Hits	168	Shared Neighborhood Hits	34
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CIC_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.062929 (rank : 208)
Query Neighborhood Hits	400	Target Neighborhood Hits	992	Shared Neighborhood Hits	127
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CISH_HUMAN
θ value	θ > 10 (rank : 425)	NC score	0.071613 (rank : 157)
Query Neighborhood Hits	400	Target Neighborhood Hits	94	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NSE2, Q9NS38, Q9Y5R1	Gene names	CISH, G18
Domain Architecture
Description	Cytokine-inducible SH2-containing protein (CIS) (CIS-1) (Suppressor of cytokine signaling) (SOCS) (Protein G18).

CISH_MOUSE
θ value	θ > 10 (rank : 426)	NC score	0.078265 (rank : 116)
Query Neighborhood Hits	400	Target Neighborhood Hits	94	Shared Neighborhood Hits	46
SwissProt Accessions	Q62225, Q3TC70	Gene names	Cish, Cis
Domain Architecture
Description	Cytokine-inducible SH2-containing protein (CIS) (CIS-1) (Suppressor of cytokine signaling) (SOCS).

CIZ1_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.050027 (rank : 328)
Query Neighborhood Hits	400	Target Neighborhood Hits	359	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

CJ078_MOUSE
θ value	θ > 10 (rank : 428)	NC score	0.077991 (rank : 117)
Query Neighborhood Hits	400	Target Neighborhood Hits	559	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CK024_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.060163 (rank : 236)
Query Neighborhood Hits	400	Target Neighborhood Hits	408	Shared Neighborhood Hits	65
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CN032_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.074983 (rank : 136)
Query Neighborhood Hits	400	Target Neighborhood Hits	267	Shared Neighborhood Hits	56
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CN032_MOUSE
θ value	θ > 10 (rank : 431)	NC score	0.066876 (rank : 186)
Query Neighborhood Hits	400	Target Neighborhood Hits	233	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CN155_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.072592 (rank : 151)
Query Neighborhood Hits	400	Target Neighborhood Hits	385	Shared Neighborhood Hits	56
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CNOT3_HUMAN
θ value	θ > 10 (rank : 433)	NC score	0.060182 (rank : 235)
Query Neighborhood Hits	400	Target Neighborhood Hits	425	Shared Neighborhood Hits	63
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CO039_MOUSE
θ value	θ > 10 (rank : 434)	NC score	0.053423 (rank : 301)
Query Neighborhood Hits	400	Target Neighborhood Hits	445	Shared Neighborhood Hits	81
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

CPSF6_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.064671 (rank : 197)
Query Neighborhood Hits	400	Target Neighborhood Hits	359	Shared Neighborhood Hits	73
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	θ > 10 (rank : 436)	NC score	0.061907 (rank : 220)
Query Neighborhood Hits	400	Target Neighborhood Hits	356	Shared Neighborhood Hits	72
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CS016_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.089455 (rank : 82)
Query Neighborhood Hits	400	Target Neighborhood Hits	310	Shared Neighborhood Hits	60
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

DIDO1_HUMAN
θ value	θ > 10 (rank : 438)	NC score	0.054185 (rank : 293)
Query Neighborhood Hits	400	Target Neighborhood Hits	960	Shared Neighborhood Hits	102
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

DOT1L_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.076379 (rank : 128)
Query Neighborhood Hits	400	Target Neighborhood Hits	660	Shared Neighborhood Hits	84
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

ENAH_MOUSE
θ value	θ > 10 (rank : 440)	NC score	0.076775 (rank : 125)
Query Neighborhood Hits	400	Target Neighborhood Hits	919	Shared Neighborhood Hits	103
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

FRK_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.054143 (rank : 294)
Query Neighborhood Hits	400	Target Neighborhood Hits	1058	Shared Neighborhood Hits	91
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

FYN_MOUSE
θ value	θ > 10 (rank : 442)	NC score	0.059775 (rank : 242)
Query Neighborhood Hits	400	Target Neighborhood Hits	1073	Shared Neighborhood Hits	91
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

GGN_HUMAN
θ value	θ > 10 (rank : 443)	NC score	0.055315 (rank : 283)
Query Neighborhood Hits	400	Target Neighborhood Hits	269	Shared Neighborhood Hits	53
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GGN_MOUSE
θ value	θ > 10 (rank : 444)	NC score	0.061168 (rank : 226)
Query Neighborhood Hits	400	Target Neighborhood Hits	311	Shared Neighborhood Hits	69
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GRB14_HUMAN
θ value	θ > 10 (rank : 445)	NC score	0.080696 (rank : 107)
Query Neighborhood Hits	400	Target Neighborhood Hits	137	Shared Neighborhood Hits	65
SwissProt Accessions	Q14449, Q7Z6I1	Gene names	GRB14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

GRB7_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.075414 (rank : 135)
Query Neighborhood Hits	400	Target Neighborhood Hits	156	Shared Neighborhood Hits	69
SwissProt Accessions	Q14451, Q92568, Q96DF9	Gene names	GRB7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).

GRB7_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.074933 (rank : 138)
Query Neighborhood Hits	400	Target Neighborhood Hits	157	Shared Neighborhood Hits	74
SwissProt Accessions	Q03160	Gene names	Grb7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7).

GRIN1_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.061148 (rank : 227)
Query Neighborhood Hits	400	Target Neighborhood Hits	681	Shared Neighborhood Hits	101
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

GSCR1_HUMAN
θ value	θ > 10 (rank : 449)	NC score	0.093316 (rank : 76)
Query Neighborhood Hits	400	Target Neighborhood Hits	674	Shared Neighborhood Hits	110
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

LCK_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.056523 (rank : 275)
Query Neighborhood Hits	400	Target Neighborhood Hits	987	Shared Neighborhood Hits	86
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

LCK_MOUSE
θ value	θ > 10 (rank : 451)	NC score	0.057080 (rank : 272)
Query Neighborhood Hits	400	Target Neighborhood Hits	981	Shared Neighborhood Hits	86
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

LCP2_MOUSE
θ value	θ > 10 (rank : 452)	NC score	0.075814 (rank : 134)
Query Neighborhood Hits	400	Target Neighborhood Hits	177	Shared Neighborhood Hits	73
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LNK_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.081474 (rank : 104)
Query Neighborhood Hits	400	Target Neighborhood Hits	151	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

MAP4_MOUSE
θ value	θ > 10 (rank : 454)	NC score	0.055823 (rank : 278)
Query Neighborhood Hits	400	Target Neighborhood Hits	409	Shared Neighborhood Hits	56
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MARCS_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.073500 (rank : 146)
Query Neighborhood Hits	400	Target Neighborhood Hits	204	Shared Neighborhood Hits	37
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MBD6_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.077915 (rank : 118)
Query Neighborhood Hits	400	Target Neighborhood Hits	349	Shared Neighborhood Hits	76
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MDC1_HUMAN
θ value	θ > 10 (rank : 457)	NC score	0.084417 (rank : 94)
Query Neighborhood Hits	400	Target Neighborhood Hits	1446	Shared Neighborhood Hits	130
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MINT_MOUSE
θ value	θ > 10 (rank : 458)	NC score	0.058964 (rank : 251)
Query Neighborhood Hits	400	Target Neighborhood Hits	1514	Shared Neighborhood Hits	136
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MLL2_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.065194 (rank : 192)
Query Neighborhood Hits	400	Target Neighborhood Hits	1788	Shared Neighborhood Hits	155
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL3_MOUSE
θ value	θ > 10 (rank : 460)	NC score	0.059896 (rank : 238)
Query Neighborhood Hits	400	Target Neighborhood Hits	1399	Shared Neighborhood Hits	129
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MLL4_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.058306 (rank : 259)
Query Neighborhood Hits	400	Target Neighborhood Hits	722	Shared Neighborhood Hits	93
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MUC1_HUMAN
θ value	θ > 10 (rank : 462)	NC score	0.080517 (rank : 108)
Query Neighborhood Hits	400	Target Neighborhood Hits	975	Shared Neighborhood Hits	118
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MUC1_MOUSE
θ value	θ > 10 (rank : 463)	NC score	0.058979 (rank : 250)
Query Neighborhood Hits	400	Target Neighborhood Hits	388	Shared Neighborhood Hits	52
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

MUC7_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.104477 (rank : 54)
Query Neighborhood Hits	400	Target Neighborhood Hits	538	Shared Neighborhood Hits	88
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NU214_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.074795 (rank : 141)
Query Neighborhood Hits	400	Target Neighborhood Hits	657	Shared Neighborhood Hits	88
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

PCLO_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.082093 (rank : 102)
Query Neighborhood Hits	400	Target Neighborhood Hits	2046	Shared Neighborhood Hits	177
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PCQAP_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.056698 (rank : 274)
Query Neighborhood Hits	400	Target Neighborhood Hits	549	Shared Neighborhood Hits	65
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PCQAP_MOUSE
θ value	θ > 10 (rank : 468)	NC score	0.051156 (rank : 320)
Query Neighborhood Hits	400	Target Neighborhood Hits	506	Shared Neighborhood Hits	62
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

PELP1_MOUSE
θ value	θ > 10 (rank : 469)	NC score	0.055652 (rank : 280)
Query Neighborhood Hits	400	Target Neighborhood Hits	709	Shared Neighborhood Hits	99
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PLCG1_HUMAN
θ value	θ > 10 (rank : 470)	NC score	0.076964 (rank : 124)
Query Neighborhood Hits	400	Target Neighborhood Hits	293	Shared Neighborhood Hits	80
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG1_MOUSE
θ value	θ > 10 (rank : 471)	NC score	0.076746 (rank : 126)
Query Neighborhood Hits	400	Target Neighborhood Hits	314	Shared Neighborhood Hits	82
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG2_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.068615 (rank : 172)
Query Neighborhood Hits	400	Target Neighborhood Hits	280	Shared Neighborhood Hits	76
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

PO121_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.055211 (rank : 285)
Query Neighborhood Hits	400	Target Neighborhood Hits	344	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PRB3_HUMAN
θ value	θ > 10 (rank : 474)	NC score	0.084664 (rank : 92)
Query Neighborhood Hits	400	Target Neighborhood Hits	318	Shared Neighborhood Hits	65
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.088424 (rank : 83)
Query Neighborhood Hits	400	Target Neighborhood Hits	330	Shared Neighborhood Hits	69
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRG4_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.084651 (rank : 93)
Query Neighborhood Hits	400	Target Neighborhood Hits	764	Shared Neighborhood Hits	97
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRG4_MOUSE
θ value	θ > 10 (rank : 477)	NC score	0.060302 (rank : 233)
Query Neighborhood Hits	400	Target Neighborhood Hits	624	Shared Neighborhood Hits	75
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRP1_HUMAN
θ value	θ > 10 (rank : 478)	NC score	0.108400 (rank : 42)
Query Neighborhood Hits	400	Target Neighborhood Hits	385	Shared Neighborhood Hits	76
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 479)	NC score	0.111306 (rank : 36)
Query Neighborhood Hits	400	Target Neighborhood Hits	347	Shared Neighborhood Hits	76
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRP5_HUMAN
θ value	θ > 10 (rank : 480)	NC score	0.082290 (rank : 101)
Query Neighborhood Hits	400	Target Neighborhood Hits	108	Shared Neighborhood Hits	33
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

PRPC_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.057407 (rank : 266)
Query Neighborhood Hits	400	Target Neighborhood Hits	165	Shared Neighborhood Hits	37
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

PRR12_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.081992 (rank : 103)
Query Neighborhood Hits	400	Target Neighborhood Hits	460	Shared Neighborhood Hits	87
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PRR13_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.050970 (rank : 322)
Query Neighborhood Hits	400	Target Neighborhood Hits	105	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PTK6_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.052466 (rank : 312)
Query Neighborhood Hits	400	Target Neighborhood Hits	1020	Shared Neighborhood Hits	85
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

PTK6_MOUSE
θ value	θ > 10 (rank : 485)	NC score	0.051876 (rank : 315)
Query Neighborhood Hits	400	Target Neighborhood Hits	1026	Shared Neighborhood Hits	87
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

RASA1_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.086113 (rank : 87)
Query Neighborhood Hits	400	Target Neighborhood Hits	258	Shared Neighborhood Hits	80
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

RERE_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.071913 (rank : 155)
Query Neighborhood Hits	400	Target Neighborhood Hits	779	Shared Neighborhood Hits	108
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RERE_MOUSE
θ value	θ > 10 (rank : 488)	NC score	0.070655 (rank : 160)
Query Neighborhood Hits	400	Target Neighborhood Hits	785	Shared Neighborhood Hits	108
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SELV_HUMAN
θ value	θ > 10 (rank : 489)	NC score	0.051135 (rank : 321)
Query Neighborhood Hits	400	Target Neighborhood Hits	118	Shared Neighborhood Hits	33
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

SET1A_HUMAN
θ value	θ > 10 (rank : 490)	NC score	0.061958 (rank : 218)
Query Neighborhood Hits	400	Target Neighborhood Hits	690	Shared Neighborhood Hits	81
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SF3A2_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.062057 (rank : 216)
Query Neighborhood Hits	400	Target Neighborhood Hits	263	Shared Neighborhood Hits	56
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SF3A2_MOUSE
θ value	θ > 10 (rank : 492)	NC score	0.055567 (rank : 281)
Query Neighborhood Hits	400	Target Neighborhood Hits	247	Shared Neighborhood Hits	57
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SFPQ_HUMAN
θ value	θ > 10 (rank : 493)	NC score	0.064459 (rank : 201)
Query Neighborhood Hits	400	Target Neighborhood Hits	986	Shared Neighborhood Hits	116
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SFPQ_MOUSE
θ value	θ > 10 (rank : 494)	NC score	0.061108 (rank : 228)
Query Neighborhood Hits	400	Target Neighborhood Hits	958	Shared Neighborhood Hits	108
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SFR15_HUMAN
θ value	θ > 10 (rank : 495)	NC score	0.053643 (rank : 300)
Query Neighborhood Hits	400	Target Neighborhood Hits	368	Shared Neighborhood Hits	60
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SH21A_HUMAN
θ value	θ > 10 (rank : 496)	NC score	0.066523 (rank : 188)
Query Neighborhood Hits	400	Target Neighborhood Hits	89	Shared Neighborhood Hits	53
SwissProt Accessions	O60880, O95383, O95384, O95385, O95386, Q9UNR0	Gene names	SH2D1A, DSHP, SAP
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP) (Duncan disease SH2-protein).

SH21A_MOUSE
θ value	θ > 10 (rank : 497)	NC score	0.068044 (rank : 176)
Query Neighborhood Hits	400	Target Neighborhood Hits	89	Shared Neighborhood Hits	54
SwissProt Accessions	O88890, Q9QWV6	Gene names	Sh2d1a, Xlp
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP).

SH21B_HUMAN
θ value	θ > 10 (rank : 498)	NC score	0.079881 (rank : 112)
Query Neighborhood Hits	400	Target Neighborhood Hits	101	Shared Neighborhood Hits	63
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

SH21B_MOUSE
θ value	θ > 10 (rank : 499)	NC score	0.086981 (rank : 85)
Query Neighborhood Hits	400	Target Neighborhood Hits	101	Shared Neighborhood Hits	62
SwissProt Accessions	O35324, Q8C268	Gene names	Sh2d1b, Eat2, Sh2d1b1
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

SH22A_HUMAN
θ value	θ > 10 (rank : 500)	NC score	0.070348 (rank : 162)
Query Neighborhood Hits	400	Target Neighborhood Hits	144	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

SH22A_MOUSE
θ value	θ > 10 (rank : 501)	NC score	0.074719 (rank : 142)
Query Neighborhood Hits	400	Target Neighborhood Hits	179	Shared Neighborhood Hits	65
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

SH23A_HUMAN
θ value	θ > 10 (rank : 502)	NC score	0.055698 (rank : 279)
Query Neighborhood Hits	400	Target Neighborhood Hits	149	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BRG2, Q9Y2X4	Gene names	SH2D3A, NSP1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3A (Novel SH2-containing protein 1).

SH24A_HUMAN
θ value	θ > 10 (rank : 503)	NC score	0.074955 (rank : 137)
Query Neighborhood Hits	400	Target Neighborhood Hits	455	Shared Neighborhood Hits	64
SwissProt Accessions	Q9H788, Q5XKC1, Q6NXE9, Q86YM2, Q96C88, Q9H7F7	Gene names	SH2D4A, SH2A
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A (Protein SH(2)A).

SH2D3_HUMAN
θ value	θ > 10 (rank : 504)	NC score	0.056762 (rank : 273)
Query Neighborhood Hits	400	Target Neighborhood Hits	188	Shared Neighborhood Hits	66
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

SH2D3_MOUSE
θ value	θ > 10 (rank : 505)	NC score	0.054372 (rank : 292)
Query Neighborhood Hits	400	Target Neighborhood Hits	174	Shared Neighborhood Hits	62
SwissProt Accessions	Q9QZS8, Q9JME1	Gene names	Sh2d3c, Chat, Shep1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (SH2 domain-containing Eph receptor- binding protein 1) (Cas/HEF1-associated signal transducer).

SHB_HUMAN
θ value	θ > 10 (rank : 506)	NC score	0.084962 (rank : 91)
Query Neighborhood Hits	400	Target Neighborhood Hits	141	Shared Neighborhood Hits	74
SwissProt Accessions	Q15464, Q504U5, Q5VUM8	Gene names	SHB
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

SHB_MOUSE
θ value	θ > 10 (rank : 507)	NC score	0.085645 (rank : 90)
Query Neighborhood Hits	400	Target Neighborhood Hits	137	Shared Neighborhood Hits	74
SwissProt Accessions	Q6PD21, Q3ULM3	Gene names	Shb
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

SHC2_HUMAN
θ value	θ > 10 (rank : 508)	NC score	0.066903 (rank : 185)
Query Neighborhood Hits	400	Target Neighborhood Hits	170	Shared Neighborhood Hits	70
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

SHC2_MOUSE
θ value	θ > 10 (rank : 509)	NC score	0.067282 (rank : 181)
Query Neighborhood Hits	400	Target Neighborhood Hits	144	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

SHC3_HUMAN
θ value	θ > 10 (rank : 510)	NC score	0.073286 (rank : 149)
Query Neighborhood Hits	400	Target Neighborhood Hits	155	Shared Neighborhood Hits	65
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

SHD_HUMAN
θ value	θ > 10 (rank : 511)	NC score	0.080859 (rank : 106)
Query Neighborhood Hits	400	Target Neighborhood Hits	204	Shared Neighborhood Hits	75
SwissProt Accessions	Q96IW2, Q96NC2	Gene names	SHD
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

SHD_MOUSE
θ value	θ > 10 (rank : 512)	NC score	0.076143 (rank : 130)
Query Neighborhood Hits	400	Target Neighborhood Hits	137	Shared Neighborhood Hits	72
SwissProt Accessions	O88834, Q3SYI7	Gene names	Shd
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

SLAP1_HUMAN
θ value	θ > 10 (rank : 513)	NC score	0.105007 (rank : 53)
Query Neighborhood Hits	400	Target Neighborhood Hits	113	Shared Neighborhood Hits	66
SwissProt Accessions	Q13239, Q9UMQ8	Gene names	SLA, SLAP, SLAP1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (hSLAP).

SLAP1_MOUSE
θ value	θ > 10 (rank : 514)	NC score	0.102335 (rank : 57)
Query Neighborhood Hits	400	Target Neighborhood Hits	117	Shared Neighborhood Hits	67
SwissProt Accessions	Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8	Gene names	Sla, Slap, Slap1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (mSLAP).

SMR3A_HUMAN
θ value	θ > 10 (rank : 515)	NC score	0.057422 (rank : 265)
Query Neighborhood Hits	400	Target Neighborhood Hits	93	Shared Neighborhood Hits	26
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

SOCS1_HUMAN
θ value	θ > 10 (rank : 516)	NC score	0.066913 (rank : 183)
Query Neighborhood Hits	400	Target Neighborhood Hits	79	Shared Neighborhood Hits	40
SwissProt Accessions	O15524, O15097, Q9NSA7	Gene names	SOCS1, SSI1, TIP3
Domain Architecture
Description	Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1) (Tec-interacting protein 3) (TIP-3).

SOCS1_MOUSE
θ value	θ > 10 (rank : 517)	NC score	0.065121 (rank : 193)
Query Neighborhood Hits	400	Target Neighborhood Hits	82	Shared Neighborhood Hits	40
SwissProt Accessions	O35716, O35960, Q3U3L0	Gene names	Socs1, Cish1, Ssi1
Domain Architecture
Description	Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1).

SOCS6_HUMAN
θ value	θ > 10 (rank : 518)	NC score	0.058009 (rank : 262)
Query Neighborhood Hits	400	Target Neighborhood Hits	126	Shared Neighborhood Hits	53
SwissProt Accessions	O14544	Gene names	SOCS6, CIS4, SOCS4
Domain Architecture
Description	Suppressor of cytokine signaling 6 (SOCS-6) (Suppressor of cytokine signaling 4) (SOCS-4) (Cytokine-inducible SH2 protein 4) (CIS-4).

SOCS6_MOUSE
θ value	θ > 10 (rank : 519)	NC score	0.059426 (rank : 246)
Query Neighborhood Hits	400	Target Neighborhood Hits	146	Shared Neighborhood Hits	57
SwissProt Accessions	Q9JLY0, Q9D2A0	Gene names	Socs6, Cis4, Cish4, Socs4
Domain Architecture
Description	Suppressor of cytokine signaling 6 (SOCS-6) (Suppressor of cytokine signaling 4) (SOCS-4) (Cytokine-inducible SH2 protein 4) (CIS-4).

SOCS7_MOUSE
θ value	θ > 10 (rank : 520)	NC score	0.073296 (rank : 148)
Query Neighborhood Hits	400	Target Neighborhood Hits	154	Shared Neighborhood Hits	69
SwissProt Accessions	Q8VHQ2	Gene names	Socs7, Cish7, Nap4
Domain Architecture
Description	Suppressor of cytokine signaling 7 (SOCS-7).

SON_HUMAN
θ value	θ > 10 (rank : 521)	NC score	0.061026 (rank : 229)
Query Neighborhood Hits	400	Target Neighborhood Hits	1568	Shared Neighborhood Hits	150
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

T22D2_HUMAN
θ value	θ > 10 (rank : 522)	NC score	0.058905 (rank : 252)
Query Neighborhood Hits	400	Target Neighborhood Hits	250	Shared Neighborhood Hits	62
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

TAF4_HUMAN
θ value	θ > 10 (rank : 523)	NC score	0.077171 (rank : 122)
Query Neighborhood Hits	400	Target Neighborhood Hits	687	Shared Neighborhood Hits	90
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TARA_HUMAN
θ value	θ > 10 (rank : 524)	NC score	0.066991 (rank : 182)
Query Neighborhood Hits	400	Target Neighborhood Hits	1626	Shared Neighborhood Hits	159
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TARSH_HUMAN
θ value	θ > 10 (rank : 525)	NC score	0.062903 (rank : 210)
Query Neighborhood Hits	400	Target Neighborhood Hits	768	Shared Neighborhood Hits	95
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TCOF_MOUSE
θ value	θ > 10 (rank : 526)	NC score	0.053871 (rank : 299)
Query Neighborhood Hits	400	Target Neighborhood Hits	471	Shared Neighborhood Hits	62
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TEC_HUMAN
θ value	θ > 10 (rank : 527)	NC score	0.058362 (rank : 258)
Query Neighborhood Hits	400	Target Neighborhood Hits	1006	Shared Neighborhood Hits	82
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TEC_MOUSE
θ value	θ > 10 (rank : 528)	NC score	0.058594 (rank : 257)
Query Neighborhood Hits	400	Target Neighborhood Hits	1006	Shared Neighborhood Hits	81
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TGON2_HUMAN
θ value	θ > 10 (rank : 529)	NC score	0.069060 (rank : 168)
Query Neighborhood Hits	400	Target Neighborhood Hits	1037	Shared Neighborhood Hits	106
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TTBK1_HUMAN
θ value	θ > 10 (rank : 530)	NC score	0.053345 (rank : 303)
Query Neighborhood Hits	400	Target Neighborhood Hits	1058	Shared Neighborhood Hits	89
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

VAV2_HUMAN
θ value	θ > 10 (rank : 531)	NC score	0.069194 (rank : 167)
Query Neighborhood Hits	400	Target Neighborhood Hits	453	Shared Neighborhood Hits	86
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
θ value	θ > 10 (rank : 532)	NC score	0.067897 (rank : 177)
Query Neighborhood Hits	400	Target Neighborhood Hits	456	Shared Neighborhood Hits	88
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

VAV3_HUMAN
θ value	θ > 10 (rank : 533)	NC score	0.057994 (rank : 263)
Query Neighborhood Hits	400	Target Neighborhood Hits	398	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV3_MOUSE
θ value	θ > 10 (rank : 534)	NC score	0.058641 (rank : 255)
Query Neighborhood Hits	400	Target Neighborhood Hits	404	Shared Neighborhood Hits	78
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

VAV_HUMAN
θ value	θ > 10 (rank : 535)	NC score	0.055444 (rank : 282)
Query Neighborhood Hits	400	Target Neighborhood Hits	452	Shared Neighborhood Hits	75
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

VAV_MOUSE
θ value	θ > 10 (rank : 536)	NC score	0.050698 (rank : 325)
Query Neighborhood Hits	400	Target Neighborhood Hits	430	Shared Neighborhood Hits	72
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

WASF1_HUMAN
θ value	θ > 10 (rank : 537)	NC score	0.050891 (rank : 324)
Query Neighborhood Hits	400	Target Neighborhood Hits	260	Shared Neighborhood Hits	56
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

WASF1_MOUSE
θ value	θ > 10 (rank : 538)	NC score	0.050267 (rank : 326)
Query Neighborhood Hits	400	Target Neighborhood Hits	261	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

WASF2_MOUSE
θ value	θ > 10 (rank : 539)	NC score	0.057196 (rank : 271)
Query Neighborhood Hits	400	Target Neighborhood Hits	315	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

WASIP_HUMAN
θ value	θ > 10 (rank : 540)	NC score	0.101095 (rank : 60)
Query Neighborhood Hits	400	Target Neighborhood Hits	458	Shared Neighborhood Hits	93
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WASIP_MOUSE
θ value	θ > 10 (rank : 541)	NC score	0.091634 (rank : 81)
Query Neighborhood Hits	400	Target Neighborhood Hits	392	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

WASL_MOUSE
θ value	θ > 10 (rank : 542)	NC score	0.071427 (rank : 158)
Query Neighborhood Hits	400	Target Neighborhood Hits	339	Shared Neighborhood Hits	77
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASP_HUMAN
θ value	θ > 10 (rank : 543)	NC score	0.051485 (rank : 317)
Query Neighborhood Hits	400	Target Neighborhood Hits	195	Shared Neighborhood Hits	49
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

WBP11_HUMAN
θ value	θ > 10 (rank : 544)	NC score	0.053960 (rank : 298)
Query Neighborhood Hits	400	Target Neighborhood Hits	354	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WIRE_HUMAN
θ value	θ > 10 (rank : 545)	NC score	0.071790 (rank : 156)
Query Neighborhood Hits	400	Target Neighborhood Hits	329	Shared Neighborhood Hits	73
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

WIRE_MOUSE
θ value	θ > 10 (rank : 546)	NC score	0.066852 (rank : 187)
Query Neighborhood Hits	400	Target Neighborhood Hits	310	Shared Neighborhood Hits	64
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

YLPM1_HUMAN
θ value	θ > 10 (rank : 547)	NC score	0.064515 (rank : 199)
Query Neighborhood Hits	400	Target Neighborhood Hits	670	Shared Neighborhood Hits	96
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

YLPM1_MOUSE
θ value	θ > 10 (rank : 548)	NC score	0.073759 (rank : 145)
Query Neighborhood Hits	400	Target Neighborhood Hits	505	Shared Neighborhood Hits	81
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ZIMP7_MOUSE
θ value	θ > 10 (rank : 549)	NC score	0.053317 (rank : 304)
Query Neighborhood Hits	400	Target Neighborhood Hits	566	Shared Neighborhood Hits	89
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ZN207_HUMAN
θ value	θ > 10 (rank : 550)	NC score	0.053993 (rank : 297)
Query Neighborhood Hits	400	Target Neighborhood Hits	326	Shared Neighborhood Hits	51
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

ZN750_MOUSE
θ value	θ > 10 (rank : 551)	NC score	0.059069 (rank : 249)
Query Neighborhood Hits	400	Target Neighborhood Hits	346	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

Hits sorted by NC score

TENS1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	400	Target Neighborhood Hits	400	Shared Neighborhood Hits	400
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

TENS4_MOUSE
NC score	0.627888 (rank : 2)	θ value	5.50685e-82 (rank : 3)
Query Neighborhood Hits	400	Target Neighborhood Hits	225	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

TENS4_HUMAN
NC score	0.625696 (rank : 3)	θ value	4.21644e-82 (rank : 2)
Query Neighborhood Hits	400	Target Neighborhood Hits	214	Shared Neighborhood Hits	76
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

PTEN_HUMAN
NC score	0.622601 (rank : 4)	θ value	9.52487e-34 (rank : 6)
Query Neighborhood Hits	400	Target Neighborhood Hits	72	Shared Neighborhood Hits	11
SwissProt Accessions	P60484, O00633, O02679, Q6ICT7	Gene names	PTEN, MMAC1, TEP1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual- specificity protein phosphatase PTEN (EC 3.1.3.67) (EC 3.1.3.16) (EC 3.1.3.48) (Phosphatase and tensin homolog) (Mutated in multiple advanced cancers 1).

PTEN_MOUSE
NC score	0.622598 (rank : 5)	θ value	9.52487e-34 (rank : 7)
Query Neighborhood Hits	400	Target Neighborhood Hits	73	Shared Neighborhood Hits	11
SwissProt Accessions	O08586, Q542G1	Gene names	Pten, Mmac1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN (EC 3.1.3.67) (Mutated in multiple advanced cancers 1).

TPTE_HUMAN
NC score	0.604970 (rank : 6)	θ value	2.96777e-27 (rank : 8)
Query Neighborhood Hits	400	Target Neighborhood Hits	53	Shared Neighborhood Hits	9
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

TPTE2_HUMAN
NC score	0.596186 (rank : 7)	θ value	2.77775e-25 (rank : 11)
Query Neighborhood Hits	400	Target Neighborhood Hits	68	Shared Neighborhood Hits	9
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

AUXI_MOUSE
NC score	0.583020 (rank : 8)	θ value	8.63488e-27 (rank : 10)
Query Neighborhood Hits	400	Target Neighborhood Hits	114	Shared Neighborhood Hits	19
SwissProt Accessions	Q80TZ3, Q6P2K9, Q8C7L9	Gene names	Dnajc6, Kiaa0473
Domain Architecture	No domain graphic available
Description	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6).

AUXI_HUMAN
NC score	0.582311 (rank : 9)	θ value	6.61148e-27 (rank : 9)
Query Neighborhood Hits	400	Target Neighborhood Hits	99	Shared Neighborhood Hits	16
SwissProt Accessions	O75061, Q32M66, Q4G0K1, Q5T614, Q5T615	Gene names	DNAJC6, KIAA0473
Domain Architecture	No domain graphic available
Description	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6).

GAK_MOUSE
NC score	0.236287 (rank : 10)	θ value	1.73584e-35 (rank : 4)
Query Neighborhood Hits	400	Target Neighborhood Hits	964	Shared Neighborhood Hits	69
SwissProt Accessions	Q99KY4, Q6P1I8, Q6P9S5, Q8BM74, Q8K0Q4	Gene names	Gak
Domain Architecture	No domain graphic available
Description	Cyclin G-associated kinase (EC 2.7.11.1).

GAK_HUMAN
NC score	0.233248 (rank : 11)	θ value	1.9192e-34 (rank : 5)
Query Neighborhood Hits	400	Target Neighborhood Hits	1028	Shared Neighborhood Hits	86
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

SLAP2_HUMAN
NC score	0.161171 (rank : 12)	θ value	0.0148317 (rank : 28)
Query Neighborhood Hits	400	Target Neighborhood Hits	139	Shared Neighborhood Hits	70
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

SLAP2_MOUSE
NC score	0.160164 (rank : 13)	θ value	0.00298849 (rank : 19)
Query Neighborhood Hits	400	Target Neighborhood Hits	136	Shared Neighborhood Hits	70
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

CRK_HUMAN
NC score	0.156954 (rank : 14)	θ value	0.00228821 (rank : 17)
Query Neighborhood Hits	400	Target Neighborhood Hits	308	Shared Neighborhood Hits	85
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
NC score	0.155193 (rank : 15)	θ value	0.00228821 (rank : 18)
Query Neighborhood Hits	400	Target Neighborhood Hits	314	Shared Neighborhood Hits	86
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

HSH2D_HUMAN
NC score	0.154258 (rank : 16)	θ value	0.0252991 (rank : 32)
Query Neighborhood Hits	400	Target Neighborhood Hits	159	Shared Neighborhood Hits	75
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

CRKL_MOUSE
NC score	0.137265 (rank : 17)	θ value	0.21417 (rank : 67)
Query Neighborhood Hits	400	Target Neighborhood Hits	307	Shared Neighborhood Hits	83
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

CRKL_HUMAN
NC score	0.135869 (rank : 18)	θ value	0.0961366 (rank : 48)
Query Neighborhood Hits	400	Target Neighborhood Hits	313	Shared Neighborhood Hits	83
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

GRAP2_HUMAN
NC score	0.129923 (rank : 19)	θ value	0.813845 (rank : 121)
Query Neighborhood Hits	400	Target Neighborhood Hits	304	Shared Neighborhood Hits	85
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

HSH2D_MOUSE
NC score	0.127524 (rank : 20)	θ value	0.47712 (rank : 100)
Query Neighborhood Hits	400	Target Neighborhood Hits	124	Shared Neighborhood Hits	57
SwissProt Accessions	Q6VYH9, Q52KL3	Gene names	Hsh2d, Alx
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

GRAP2_MOUSE
NC score	0.124893 (rank : 21)	θ value	2.36792 (rank : 201)
Query Neighborhood Hits	400	Target Neighborhood Hits	297	Shared Neighborhood Hits	83
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

P55G_MOUSE
NC score	0.124483 (rank : 22)	θ value	0.365318 (rank : 89)
Query Neighborhood Hits	400	Target Neighborhood Hits	401	Shared Neighborhood Hits	74
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P85B_HUMAN
NC score	0.123823 (rank : 23)	θ value	0.365318 (rank : 90)
Query Neighborhood Hits	400	Target Neighborhood Hits	543	Shared Neighborhood Hits	87
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

SRRM2_MOUSE
NC score	0.122449 (rank : 24)	θ value	0.0563607 (rank : 45)
Query Neighborhood Hits	400	Target Neighborhood Hits	1470	Shared Neighborhood Hits	170
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

LCP2_HUMAN
NC score	0.119834 (rank : 25)	θ value	0.00869519 (rank : 22)
Query Neighborhood Hits	400	Target Neighborhood Hits	531	Shared Neighborhood Hits	118
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

P55G_HUMAN
NC score	0.119608 (rank : 26)	θ value	0.813845 (rank : 129)
Query Neighborhood Hits	400	Target Neighborhood Hits	451	Shared Neighborhood Hits	76
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

SRRM1_MOUSE
NC score	0.118839 (rank : 27)	θ value	1.38821 (rank : 164)
Query Neighborhood Hits	400	Target Neighborhood Hits	966	Shared Neighborhood Hits	138
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

MDC1_MOUSE
NC score	0.117911 (rank : 28)	θ value	0.000121331 (rank : 14)
Query Neighborhood Hits	400	Target Neighborhood Hits	998	Shared Neighborhood Hits	121
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

GRAP_MOUSE
NC score	0.117684 (rank : 29)	θ value	2.36792 (rank : 202)
Query Neighborhood Hits	400	Target Neighborhood Hits	309	Shared Neighborhood Hits	82
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

GRAP_HUMAN
NC score	0.117007 (rank : 30)	θ value	5.27518 (rank : 315)
Query Neighborhood Hits	400	Target Neighborhood Hits	307	Shared Neighborhood Hits	82
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

SRRM2_HUMAN
NC score	0.115848 (rank : 31)	θ value	0.0961366 (rank : 53)
Query Neighborhood Hits	400	Target Neighborhood Hits	1296	Shared Neighborhood Hits	148
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

BSN_MOUSE
NC score	0.115370 (rank : 32)	θ value	0.0148317 (rank : 25)
Query Neighborhood Hits	400	Target Neighborhood Hits	2057	Shared Neighborhood Hits	193
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

P85B_MOUSE
NC score	0.114133 (rank : 33)	θ value	0.365318 (rank : 91)
Query Neighborhood Hits	400	Target Neighborhood Hits	519	Shared Neighborhood Hits	85
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

GRB2_HUMAN
NC score	0.113858 (rank : 34)	θ value	4.03905 (rank : 270)
Query Neighborhood Hits	400	Target Neighborhood Hits	310	Shared Neighborhood Hits	82
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
NC score	0.113799 (rank : 35)	θ value	4.03905 (rank : 271)
Query Neighborhood Hits	400	Target Neighborhood Hits	312	Shared Neighborhood Hits	82
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

PRP2_MOUSE
NC score	0.111306 (rank : 36)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	400	Target Neighborhood Hits	347	Shared Neighborhood Hits	76
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

SRRM1_HUMAN
NC score	0.111302 (rank : 37)	θ value	1.06291 (rank : 151)
Query Neighborhood Hits	400	Target Neighborhood Hits	690	Shared Neighborhood Hits	104
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SOCS3_MOUSE
NC score	0.111204 (rank : 38)	θ value	0.365318 (rank : 95)
Query Neighborhood Hits	400	Target Neighborhood Hits	72	Shared Neighborhood Hits	48
SwissProt Accessions	O35718, P97803, Q3U7X5	Gene names	Socs3, Cis3, Cish3
Domain Architecture
Description	Suppressor of cytokine signaling 3 (SOCS-3) (Cytokine-inducible SH2 protein 3) (CIS-3) (Protein EF-10).

ALEX_HUMAN
NC score	0.109862 (rank : 39)	θ value	0.279714 (rank : 72)
Query Neighborhood Hits	400	Target Neighborhood Hits	361	Shared Neighborhood Hits	72
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

P85A_MOUSE
NC score	0.109842 (rank : 40)	θ value	1.06291 (rank : 144)
Query Neighborhood Hits	400	Target Neighborhood Hits	435	Shared Neighborhood Hits	80
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

SHE_MOUSE
NC score	0.108799 (rank : 41)	θ value	0.47712 (rank : 107)
Query Neighborhood Hits	400	Target Neighborhood Hits	169	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BSD5, Q3TZT0	Gene names	She
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

PRP1_HUMAN
NC score	0.108400 (rank : 42)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	400	Target Neighborhood Hits	385	Shared Neighborhood Hits	76
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

CBP_HUMAN
NC score	0.108010 (rank : 43)	θ value	0.21417 (rank : 66)
Query Neighborhood Hits	400	Target Neighborhood Hits	941	Shared Neighborhood Hits	129
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

ARI1A_HUMAN
NC score	0.108002 (rank : 44)	θ value	0.125558 (rank : 56)
Query Neighborhood Hits	400	Target Neighborhood Hits	787	Shared Neighborhood Hits	123
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

GRB14_MOUSE
NC score	0.107963 (rank : 45)	θ value	0.813845 (rank : 122)
Query Neighborhood Hits	400	Target Neighborhood Hits	149	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JLM9, Q3UI77, Q8VDI2, Q9CR03	Gene names	Grb14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

SOCS3_HUMAN
NC score	0.107899 (rank : 46)	θ value	1.06291 (rank : 148)
Query Neighborhood Hits	400	Target Neighborhood Hits	77	Shared Neighborhood Hits	49
SwissProt Accessions	O14543, O14509	Gene names	SOCS3, CIS3, SSI3
Domain Architecture
Description	Suppressor of cytokine signaling 3 (SOCS-3) (Cytokine-inducible SH2 protein 3) (CIS-3) (STAT-induced STAT inhibitor 3) (SSI-3).

NCK2_HUMAN
NC score	0.107680 (rank : 47)	θ value	8.99809 (rank : 383)
Query Neighborhood Hits	400	Target Neighborhood Hits	310	Shared Neighborhood Hits	87
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

CBP_MOUSE
NC score	0.106643 (rank : 48)	θ value	0.0148317 (rank : 26)
Query Neighborhood Hits	400	Target Neighborhood Hits	1051	Shared Neighborhood Hits	126
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

PRRT3_HUMAN
NC score	0.106271 (rank : 49)	θ value	0.0563607 (rank : 42)
Query Neighborhood Hits	400	Target Neighborhood Hits	998	Shared Neighborhood Hits	126
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

NCK1_HUMAN
NC score	0.105911 (rank : 50)	θ value	3.0926 (rank : 242)
Query Neighborhood Hits	400	Target Neighborhood Hits	312	Shared Neighborhood Hits	79
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

NCOA6_HUMAN
NC score	0.105286 (rank : 51)	θ value	0.365318 (rank : 88)
Query Neighborhood Hits	400	Target Neighborhood Hits	1202	Shared Neighborhood Hits	142
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

P85A_HUMAN
NC score	0.105188 (rank : 52)	θ value	1.06291 (rank : 143)
Query Neighborhood Hits	400	Target Neighborhood Hits	479	Shared Neighborhood Hits	78
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

SLAP1_HUMAN
NC score	0.105007 (rank : 53)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	400	Target Neighborhood Hits	113	Shared Neighborhood Hits	66
SwissProt Accessions	Q13239, Q9UMQ8	Gene names	SLA, SLAP, SLAP1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (hSLAP).

MUC7_HUMAN
NC score	0.104477 (rank : 54)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	400	Target Neighborhood Hits	538	Shared Neighborhood Hits	88
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

DAPP1_MOUSE
NC score	0.104468 (rank : 55)	θ value	5.27518 (rank : 312)
Query Neighborhood Hits	400	Target Neighborhood Hits	225	Shared Neighborhood Hits	82
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_HUMAN
NC score	0.102432 (rank : 56)	θ value	8.99809 (rank : 376)
Query Neighborhood Hits	400	Target Neighborhood Hits	227	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

SLAP1_MOUSE
NC score	0.102335 (rank : 57)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	400	Target Neighborhood Hits	117	Shared Neighborhood Hits	67
SwissProt Accessions	Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8	Gene names	Sla, Slap, Slap1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (mSLAP).

SPT5H_MOUSE
NC score	0.101802 (rank : 58)	θ value	0.0563607 (rank : 44)
Query Neighborhood Hits	400	Target Neighborhood Hits	437	Shared Neighborhood Hits	84
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

BAG3_MOUSE
NC score	0.101601 (rank : 59)	θ value	0.0330416 (rank : 36)
Query Neighborhood Hits	400	Target Neighborhood Hits	513	Shared Neighborhood Hits	84
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

WASIP_HUMAN
NC score	0.101095 (rank : 60)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	400	Target Neighborhood Hits	458	Shared Neighborhood Hits	93
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

EP300_HUMAN
NC score	0.100311 (rank : 61)	θ value	3.0926 (rank : 234)
Query Neighborhood Hits	400	Target Neighborhood Hits	821	Shared Neighborhood Hits	127
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

SPT5H_HUMAN
NC score	0.099167 (rank : 62)	θ value	0.0961366 (rank : 52)
Query Neighborhood Hits	400	Target Neighborhood Hits	436	Shared Neighborhood Hits	82
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SH2D5_HUMAN
NC score	0.099101 (rank : 63)	θ value	0.0193708 (rank : 30)
Query Neighborhood Hits	400	Target Neighborhood Hits	28	Shared Neighborhood Hits	16
SwissProt Accessions	Q6ZV89, Q5SSJ2	Gene names	SH2D5
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 5.

BSN_HUMAN
NC score	0.098915 (rank : 64)	θ value	6.88961 (rank : 335)
Query Neighborhood Hits	400	Target Neighborhood Hits	1537	Shared Neighborhood Hits	160
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

NCOA6_MOUSE
NC score	0.098194 (rank : 65)	θ value	0.813845 (rank : 126)
Query Neighborhood Hits	400	Target Neighborhood Hits	1076	Shared Neighborhood Hits	123
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

BAT2_MOUSE
NC score	0.097143 (rank : 66)	θ value	0.813845 (rank : 119)
Query Neighborhood Hits	400	Target Neighborhood Hits	947	Shared Neighborhood Hits	139
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

SH24A_MOUSE
NC score	0.096381 (rank : 67)	θ value	4.03905 (rank : 288)
Query Neighborhood Hits	400	Target Neighborhood Hits	326	Shared Neighborhood Hits	57
SwissProt Accessions	Q9D7V1	Gene names	Sh2d4a
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A.

RGS3_MOUSE
NC score	0.096096 (rank : 68)	θ value	0.000270298 (rank : 15)
Query Neighborhood Hits	400	Target Neighborhood Hits	1621	Shared Neighborhood Hits	164
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

ARI1B_HUMAN
NC score	0.095666 (rank : 69)	θ value	1.81305 (rank : 170)
Query Neighborhood Hits	400	Target Neighborhood Hits	567	Shared Neighborhood Hits	103
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

SHE_HUMAN
NC score	0.095004 (rank : 70)	θ value	1.81305 (rank : 185)
Query Neighborhood Hits	400	Target Neighborhood Hits	164	Shared Neighborhood Hits	71
SwissProt Accessions	Q5VZ18, Q8TEQ5	Gene names	SHE
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

SYN1_MOUSE
NC score	0.094644 (rank : 71)	θ value	0.813845 (rank : 134)
Query Neighborhood Hits	400	Target Neighborhood Hits	363	Shared Neighborhood Hits	82
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

NACAM_MOUSE
NC score	0.094413 (rank : 72)	θ value	1.06291 (rank : 141)
Query Neighborhood Hits	400	Target Neighborhood Hits	1866	Shared Neighborhood Hits	186
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

SC24C_HUMAN
NC score	0.094031 (rank : 73)	θ value	0.0563607 (rank : 43)
Query Neighborhood Hits	400	Target Neighborhood Hits	662	Shared Neighborhood Hits	96
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

LNK_MOUSE
NC score	0.093988 (rank : 74)	θ value	4.03905 (rank : 274)
Query Neighborhood Hits	400	Target Neighborhood Hits	132	Shared Neighborhood Hits	63
SwissProt Accessions	O09039	Gene names	Lnk
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

SYN1_HUMAN
NC score	0.093741 (rank : 75)	θ value	2.36792 (rank : 225)
Query Neighborhood Hits	400	Target Neighborhood Hits	419	Shared Neighborhood Hits	92
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

GSCR1_HUMAN
NC score	0.093316 (rank : 76)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	400	Target Neighborhood Hits	674	Shared Neighborhood Hits	110
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

PCLO_MOUSE
NC score	0.093214 (rank : 77)	θ value	0.163984 (rank : 64)
Query Neighborhood Hits	400	Target Neighborhood Hits	2275	Shared Neighborhood Hits	190
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

OGFR_HUMAN
NC score	0.093175 (rank : 78)	θ value	0.47712 (rank : 103)
Query Neighborhood Hits	400	Target Neighborhood Hits	1582	Shared Neighborhood Hits	160
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

ATX2L_MOUSE
NC score	0.092535 (rank : 79)	θ value	0.0148317 (rank : 24)
Query Neighborhood Hits	400	Target Neighborhood Hits	401	Shared Neighborhood Hits	72
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

TAU_HUMAN
NC score	0.092271 (rank : 80)	θ value	0.0193708 (rank : 31)
Query Neighborhood Hits	400	Target Neighborhood Hits	448	Shared Neighborhood Hits	69
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

WASIP_MOUSE
NC score	0.091634 (rank : 81)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	400	Target Neighborhood Hits	392	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

CS016_HUMAN
NC score	0.089455 (rank : 82)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	400	Target Neighborhood Hits	310	Shared Neighborhood Hits	60
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

PRB4S_HUMAN
NC score	0.088424 (rank : 83)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	400	Target Neighborhood Hits	330	Shared Neighborhood Hits	69
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

HORN_HUMAN
NC score	0.087242 (rank : 84)	θ value	4.1701e-05 (rank : 13)
Query Neighborhood Hits	400	Target Neighborhood Hits	206	Shared Neighborhood Hits	21
SwissProt Accessions	Q86YZ3	Gene names	HRNR, S100A18
Domain Architecture	No domain graphic available
Description	Hornerin.

SH21B_MOUSE
NC score	0.086981 (rank : 85)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	400	Target Neighborhood Hits	101	Shared Neighborhood Hits	62
SwissProt Accessions	O35324, Q8C268	Gene names	Sh2d1b, Eat2, Sh2d1b1
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

GRB10_MOUSE
NC score	0.086953 (rank : 86)	θ value	2.36792 (rank : 203)
Query Neighborhood Hits	400	Target Neighborhood Hits	156	Shared Neighborhood Hits	65
SwissProt Accessions	Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5	Gene names	Grb10
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein).

RASA1_HUMAN
NC score	0.086113 (rank : 87)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	400	Target Neighborhood Hits	258	Shared Neighborhood Hits	80
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

GRB10_HUMAN
NC score	0.086067 (rank : 88)	θ value	3.0926 (rank : 238)
Query Neighborhood Hits	400	Target Neighborhood Hits	147	Shared Neighborhood Hits	67
SwissProt Accessions	Q13322, O00427, O00701, O75222, Q92606, Q92907, Q92948	Gene names	GRB10, GRBIR, KIAA0207
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein) (Insulin receptor-binding protein GRB-IR).

BAT2_HUMAN
NC score	0.085749 (rank : 89)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	400	Target Neighborhood Hits	931	Shared Neighborhood Hits	131
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

SHB_MOUSE
NC score	0.085645 (rank : 90)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	400	Target Neighborhood Hits	137	Shared Neighborhood Hits	74
SwissProt Accessions	Q6PD21, Q3ULM3	Gene names	Shb
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

SHB_HUMAN
NC score	0.084962 (rank : 91)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	400	Target Neighborhood Hits	141	Shared Neighborhood Hits	74
SwissProt Accessions	Q15464, Q504U5, Q5VUM8	Gene names	SHB
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

PRB3_HUMAN
NC score	0.084664 (rank : 92)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	400	Target Neighborhood Hits	318	Shared Neighborhood Hits	65
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRG4_HUMAN
NC score	0.084651 (rank : 93)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	400	Target Neighborhood Hits	764	Shared Neighborhood Hits	97
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

MDC1_HUMAN
NC score	0.084417 (rank : 94)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	400	Target Neighborhood Hits	1446	Shared Neighborhood Hits	130
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

SHC3_MOUSE
NC score	0.084232 (rank : 95)	θ value	0.813845 (rank : 133)
Query Neighborhood Hits	400	Target Neighborhood Hits	151	Shared Neighborhood Hits	68
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

ATN1_HUMAN
NC score	0.084045 (rank : 96)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	400	Target Neighborhood Hits	676	Shared Neighborhood Hits	103
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

MAML3_HUMAN
NC score	0.083782 (rank : 97)	θ value	1.38821 (rank : 159)
Query Neighborhood Hits	400	Target Neighborhood Hits	323	Shared Neighborhood Hits	71
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

SOCS2_MOUSE
NC score	0.083669 (rank : 98)	θ value	1.06291 (rank : 147)
Query Neighborhood Hits	400	Target Neighborhood Hits	94	Shared Neighborhood Hits	51
SwissProt Accessions	O35717	Gene names	Socs2, Cis2, Cish2
Domain Architecture
Description	Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2) (CIS-2).

RAPH1_HUMAN
NC score	0.083176 (rank : 99)	θ value	5.27518 (rank : 326)
Query Neighborhood Hits	400	Target Neighborhood Hits	593	Shared Neighborhood Hits	90
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

K1802_MOUSE
NC score	0.082362 (rank : 100)	θ value	0.0252991 (rank : 33)
Query Neighborhood Hits	400	Target Neighborhood Hits	1596	Shared Neighborhood Hits	142
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

PRP5_HUMAN
NC score	0.082290 (rank : 101)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	400	Target Neighborhood Hits	108	Shared Neighborhood Hits	33
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

PCLO_HUMAN
NC score	0.082093 (rank : 102)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	400	Target Neighborhood Hits	2046	Shared Neighborhood Hits	177
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PRR12_HUMAN
NC score	0.081992 (rank : 103)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	400	Target Neighborhood Hits	460	Shared Neighborhood Hits	87
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

LNK_HUMAN
NC score	0.081474 (rank : 104)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	400	Target Neighborhood Hits	151	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

MGRN1_HUMAN
NC score	0.081173 (rank : 105)	θ value	0.000602161 (rank : 16)
Query Neighborhood Hits	400	Target Neighborhood Hits	192	Shared Neighborhood Hits	12
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

SHD_HUMAN
NC score	0.080859 (rank : 106)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	400	Target Neighborhood Hits	204	Shared Neighborhood Hits	75
SwissProt Accessions	Q96IW2, Q96NC2	Gene names	SHD
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

GRB14_HUMAN
NC score	0.080696 (rank : 107)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	400	Target Neighborhood Hits	137	Shared Neighborhood Hits	65
SwissProt Accessions	Q14449, Q7Z6I1	Gene names	GRB14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

MUC1_HUMAN
NC score	0.080517 (rank : 108)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	400	Target Neighborhood Hits	975	Shared Neighborhood Hits	118
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MAGE1_HUMAN
NC score	0.080316 (rank : 109)	θ value	5.27518 (rank : 318)
Query Neighborhood Hits	400	Target Neighborhood Hits	1389	Shared Neighborhood Hits	167
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

SHC1_MOUSE
NC score	0.080195 (rank : 110)	θ value	4.03905 (rank : 290)
Query Neighborhood Hits	400	Target Neighborhood Hits	180	Shared Neighborhood Hits	72
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

CIC_MOUSE
NC score	0.080096 (rank : 111)	θ value	1.81305 (rank : 173)
Query Neighborhood Hits	400	Target Neighborhood Hits	742	Shared Neighborhood Hits	119
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SH21B_HUMAN
NC score	0.079881 (rank : 112)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	400	Target Neighborhood Hits	101	Shared Neighborhood Hits	63
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

NFH_MOUSE
NC score	0.079660 (rank : 113)	θ value	2.44474e-05 (rank : 12)
Query Neighborhood Hits	400	Target Neighborhood Hits	2247	Shared Neighborhood Hits	174
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SHC1_HUMAN
NC score	0.079268 (rank : 114)	θ value	4.03905 (rank : 289)
Query Neighborhood Hits	400	Target Neighborhood Hits	170	Shared Neighborhood Hits	71
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

MUC2_HUMAN
NC score	0.078674 (rank : 115)	θ value	0.0736092 (rank : 47)
Query Neighborhood Hits	400	Target Neighborhood Hits	906	Shared Neighborhood Hits	94
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

CISH_MOUSE
NC score	0.078265 (rank : 116)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	400	Target Neighborhood Hits	94	Shared Neighborhood Hits	46
SwissProt Accessions	Q62225, Q3TC70	Gene names	Cish, Cis
Domain Architecture
Description	Cytokine-inducible SH2-containing protein (CIS) (CIS-1) (Suppressor of cytokine signaling) (SOCS).

CJ078_MOUSE
NC score	0.077991 (rank : 117)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	400	Target Neighborhood Hits	559	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

MBD6_HUMAN
NC score	0.077915 (rank : 118)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	400	Target Neighborhood Hits	349	Shared Neighborhood Hits	76
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

TB182_HUMAN
NC score	0.077412 (rank : 119)	θ value	4.03905 (rank : 293)
Query Neighborhood Hits	400	Target Neighborhood Hits	414	Shared Neighborhood Hits	71
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

BCL9_HUMAN
NC score	0.077385 (rank : 120)	θ value	4.03905 (rank : 261)
Query Neighborhood Hits	400	Target Neighborhood Hits	1008	Shared Neighborhood Hits	135
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

MUC13_MOUSE
NC score	0.077348 (rank : 121)	θ value	0.365318 (rank : 87)
Query Neighborhood Hits	400	Target Neighborhood Hits	447	Shared Neighborhood Hits	55
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

TAF4_HUMAN
NC score	0.077171 (rank : 122)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	400	Target Neighborhood Hits	687	Shared Neighborhood Hits	90
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

SH2D5_MOUSE
NC score	0.076977 (rank : 123)	θ value	0.47712 (rank : 106)
Query Neighborhood Hits	400	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	Q8JZW5	Gene names	Sh2d5
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 5.

PLCG1_HUMAN
NC score	0.076964 (rank : 124)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	400	Target Neighborhood Hits	293	Shared Neighborhood Hits	80
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

ENAH_MOUSE
NC score	0.076775 (rank : 125)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	400	Target Neighborhood Hits	919	Shared Neighborhood Hits	103
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

PLCG1_MOUSE
NC score	0.076746 (rank : 126)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	400	Target Neighborhood Hits	314	Shared Neighborhood Hits	82
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

TFG_HUMAN
NC score	0.076668 (rank : 127)	θ value	3.0926 (rank : 256)
Query Neighborhood Hits	400	Target Neighborhood Hits	122	Shared Neighborhood Hits	37
SwissProt Accessions	Q92734, Q15656	Gene names	TFG
Domain Architecture
Description	Protein TFG (TRK-fused gene protein).

DOT1L_HUMAN
NC score	0.076379 (rank : 128)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	400	Target Neighborhood Hits	660	Shared Neighborhood Hits	84
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

TCGAP_HUMAN
NC score	0.076372 (rank : 129)	θ value	0.00298849 (rank : 20)
Query Neighborhood Hits	400	Target Neighborhood Hits	872	Shared Neighborhood Hits	119
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

SHD_MOUSE
NC score	0.076143 (rank : 130)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	400	Target Neighborhood Hits	137	Shared Neighborhood Hits	72
SwissProt Accessions	O88834, Q3SYI7	Gene names	Shd
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

BAG3_HUMAN
NC score	0.075960 (rank : 131)	θ value	2.36792 (rank : 192)
Query Neighborhood Hits	400	Target Neighborhood Hits	314	Shared Neighborhood Hits	57
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

PTN11_MOUSE
NC score	0.075946 (rank : 132)	θ value	0.21417 (rank : 70)
Query Neighborhood Hits	400	Target Neighborhood Hits	227	Shared Neighborhood Hits	78
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN11_HUMAN
NC score	0.075936 (rank : 133)	θ value	0.21417 (rank : 69)
Query Neighborhood Hits	400	Target Neighborhood Hits	227	Shared Neighborhood Hits	78
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

LCP2_MOUSE
NC score	0.075814 (rank : 134)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	400	Target Neighborhood Hits	177	Shared Neighborhood Hits	73
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

GRB7_HUMAN
NC score	0.075414 (rank : 135)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	400	Target Neighborhood Hits	156	Shared Neighborhood Hits	69
SwissProt Accessions	Q14451, Q92568, Q96DF9	Gene names	GRB7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).

CN032_HUMAN
NC score	0.074983 (rank : 136)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	400	Target Neighborhood Hits	267	Shared Neighborhood Hits	56
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

SH24A_HUMAN
NC score	0.074955 (rank : 137)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	400	Target Neighborhood Hits	455	Shared Neighborhood Hits	64
SwissProt Accessions	Q9H788, Q5XKC1, Q6NXE9, Q86YM2, Q96C88, Q9H7F7	Gene names	SH2D4A, SH2A
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A (Protein SH(2)A).

GRB7_MOUSE
NC score	0.074933 (rank : 138)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	400	Target Neighborhood Hits	157	Shared Neighborhood Hits	74
SwissProt Accessions	Q03160	Gene names	Grb7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7).

TAU_MOUSE
NC score	0.074917 (rank : 139)	θ value	1.38821 (rank : 165)
Query Neighborhood Hits	400	Target Neighborhood Hits	502	Shared Neighborhood Hits	83
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

ATX2L_HUMAN
NC score	0.074815 (rank : 140)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	400	Target Neighborhood Hits	443	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

NU214_HUMAN
NC score	0.074795 (rank : 141)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	400	Target Neighborhood Hits	657	Shared Neighborhood Hits	88
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

SH22A_MOUSE
NC score	0.074719 (rank : 142)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	400	Target Neighborhood Hits	179	Shared Neighborhood Hits	65
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

APS_HUMAN
NC score	0.074477 (rank : 143)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	400	Target Neighborhood Hits	162	Shared Neighborhood Hits	68
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

BASP_MOUSE
NC score	0.074306 (rank : 144)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	400	Target Neighborhood Hits	260	Shared Neighborhood Hits	44
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

YLPM1_MOUSE
NC score	0.073759 (rank : 145)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	400	Target Neighborhood Hits	505	Shared Neighborhood Hits	81
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

MARCS_HUMAN
NC score	0.073500 (rank : 146)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	400	Target Neighborhood Hits	204	Shared Neighborhood Hits	37
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

ZN750_HUMAN
NC score	0.073303 (rank : 147)	θ value	0.0252991 (rank : 35)
Query Neighborhood Hits	400	Target Neighborhood Hits	183	Shared Neighborhood Hits	32
SwissProt Accessions	Q32MQ0, Q9H899	Gene names	ZNF750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

SOCS7_MOUSE
NC score	0.073296 (rank : 148)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	400	Target Neighborhood Hits	154	Shared Neighborhood Hits	69
SwissProt Accessions	Q8VHQ2	Gene names	Socs7, Cish7, Nap4
Domain Architecture
Description	Suppressor of cytokine signaling 7 (SOCS-7).

SHC3_HUMAN
NC score	0.073286 (rank : 149)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	400	Target Neighborhood Hits	155	Shared Neighborhood Hits	65
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

SOCS2_HUMAN
NC score	0.072930 (rank : 150)	θ value	6.88961 (rank : 357)
Query Neighborhood Hits	400	Target Neighborhood Hits	104	Shared Neighborhood Hits	51
SwissProt Accessions	O14508, O14542, O95102, Q9UKS5	Gene names	SOCS2, CIS2, SSI2, STATI2
Domain Architecture
Description	Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2) (CIS-2) (STAT-induced STAT inhibitor 2) (SSI-2).

CN155_HUMAN
NC score	0.072592 (rank : 151)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	400	Target Neighborhood Hits	385	Shared Neighborhood Hits	56
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

RPB1_MOUSE
NC score	0.072446 (rank : 152)	θ value	2.36792 (rank : 222)
Query Neighborhood Hits	400	Target Neighborhood Hits	363	Shared Neighborhood Hits	71
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_HUMAN
NC score	0.072381 (rank : 153)	θ value	2.36792 (rank : 221)
Query Neighborhood Hits	400	Target Neighborhood Hits	362	Shared Neighborhood Hits	72
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

ATX2_HUMAN
NC score	0.072162 (rank : 154)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	400	Target Neighborhood Hits	375	Shared Neighborhood Hits	68
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

RERE_HUMAN
NC score	0.071913 (rank : 155)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	400	Target Neighborhood Hits	779	Shared Neighborhood Hits	108
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

WIRE_HUMAN
NC score	0.071790 (rank : 156)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	400	Target Neighborhood Hits	329	Shared Neighborhood Hits	73
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

CISH_HUMAN
NC score	0.071613 (rank : 157)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	400	Target Neighborhood Hits	94	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NSE2, Q9NS38, Q9Y5R1	Gene names	CISH, G18
Domain Architecture
Description	Cytokine-inducible SH2-containing protein (CIS) (CIS-1) (Suppressor of cytokine signaling) (SOCS) (Protein G18).

WASL_MOUSE
NC score	0.071427 (rank : 158)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	400	Target Neighborhood Hits	339	Shared Neighborhood Hits	77
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

SELPL_MOUSE
NC score	0.071178 (rank : 159)	θ value	4.03905 (rank : 287)
Query Neighborhood Hits	400	Target Neighborhood Hits	588	Shared Neighborhood Hits	78
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

RERE_MOUSE
NC score	0.070655 (rank : 160)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	400	Target Neighborhood Hits	785	Shared Neighborhood Hits	108
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

MLL3_HUMAN
NC score	0.070544 (rank : 161)	θ value	0.279714 (rank : 75)
Query Neighborhood Hits	400	Target Neighborhood Hits	1644	Shared Neighborhood Hits	137
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

SH22A_HUMAN
NC score	0.070348 (rank : 162)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	400	Target Neighborhood Hits	144	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

WASL_HUMAN
NC score	0.070321 (rank : 163)	θ value	5.27518 (rank : 330)
Query Neighborhood Hits	400	Target Neighborhood Hits	312	Shared Neighborhood Hits	66
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

ABL1_MOUSE
NC score	0.070288 (rank : 164)	θ value	0.163984 (rank : 62)
Query Neighborhood Hits	400	Target Neighborhood Hits	1178	Shared Neighborhood Hits	136
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

RIN1_HUMAN
NC score	0.069663 (rank : 165)	θ value	0.813845 (rank : 132)
Query Neighborhood Hits	400	Target Neighborhood Hits	52	Shared Neighborhood Hits	11
SwissProt Accessions	Q13671, O15010, Q00427, Q96CC8	Gene names	RIN1
Domain Architecture
Description	Ras and Rab interactor 1 (Ras interaction/interference protein 1) (Ras inhibitor JC99).

BCL9_MOUSE
NC score	0.069494 (rank : 166)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	400	Target Neighborhood Hits	770	Shared Neighborhood Hits	110
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

VAV2_HUMAN
NC score	0.069194 (rank : 167)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	400	Target Neighborhood Hits	453	Shared Neighborhood Hits	86
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

TGON2_HUMAN
NC score	0.069060 (rank : 168)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	400	Target Neighborhood Hits	1037	Shared Neighborhood Hits	106
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

MUCDL_HUMAN
NC score	0.068890 (rank : 169)	θ value	5.27518 (rank : 321)
Query Neighborhood Hits	400	Target Neighborhood Hits	777	Shared Neighborhood Hits	109
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

WASP_MOUSE
NC score	0.068642 (rank : 170)	θ value	0.47712 (rank : 108)
Query Neighborhood Hits	400	Target Neighborhood Hits	223	Shared Neighborhood Hits	53
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

ALEX_MOUSE
NC score	0.068631 (rank : 171)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	400	Target Neighborhood Hits	197	Shared Neighborhood Hits	50
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

PLCG2_HUMAN
NC score	0.068615 (rank : 172)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	400	Target Neighborhood Hits	280	Shared Neighborhood Hits	76
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

ATX2_MOUSE
NC score	0.068257 (rank : 173)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	400	Target Neighborhood Hits	445	Shared Neighborhood Hits	87
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

CSK_HUMAN
NC score	0.068246 (rank : 174)	θ value	0.0961366 (rank : 49)
Query Neighborhood Hits	400	Target Neighborhood Hits	1009	Shared Neighborhood Hits	93
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

CSK_MOUSE
NC score	0.068061 (rank : 175)	θ value	0.0961366 (rank : 50)
Query Neighborhood Hits	400	Target Neighborhood Hits	1009	Shared Neighborhood Hits	93
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

SH21A_MOUSE
NC score	0.068044 (rank : 176)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	400	Target Neighborhood Hits	89	Shared Neighborhood Hits	54
SwissProt Accessions	O88890, Q9QWV6	Gene names	Sh2d1a, Xlp
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP).

VAV2_MOUSE
NC score	0.067897 (rank : 177)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	400	Target Neighborhood Hits	456	Shared Neighborhood Hits	88
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

MAML1_MOUSE
NC score	0.067836 (rank : 178)	θ value	0.47712 (rank : 101)
Query Neighborhood Hits	400	Target Neighborhood Hits	279	Shared Neighborhood Hits	57
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

FGR_MOUSE
NC score	0.067658 (rank : 179)	θ value	0.47712 (rank : 98)
Query Neighborhood Hits	400	Target Neighborhood Hits	1069	Shared Neighborhood Hits	97
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

ABL1_HUMAN
NC score	0.067463 (rank : 180)	θ value	0.163984 (rank : 61)
Query Neighborhood Hits	400	Target Neighborhood Hits	1220	Shared Neighborhood Hits	124
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

SHC2_MOUSE
NC score	0.067282 (rank : 181)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	400	Target Neighborhood Hits	144	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

TARA_HUMAN
NC score	0.066991 (rank : 182)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	400	Target Neighborhood Hits	1626	Shared Neighborhood Hits	159
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SOCS1_HUMAN
NC score	0.066913 (rank : 183)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	400	Target Neighborhood Hits	79	Shared Neighborhood Hits	40
SwissProt Accessions	O15524, O15097, Q9NSA7	Gene names	SOCS1, SSI1, TIP3
Domain Architecture
Description	Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1) (Tec-interacting protein 3) (TIP-3).

MARCS_MOUSE
NC score	0.066913 (rank : 184)	θ value	6.88961 (rank : 347)
Query Neighborhood Hits	400	Target Neighborhood Hits	227	Shared Neighborhood Hits	38
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

SHC2_HUMAN
NC score	0.066903 (rank : 185)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	400	Target Neighborhood Hits	170	Shared Neighborhood Hits	70
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

CN032_MOUSE
NC score	0.066876 (rank : 186)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	400	Target Neighborhood Hits	233	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

WIRE_MOUSE
NC score	0.066852 (rank : 187)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	400	Target Neighborhood Hits	310	Shared Neighborhood Hits	64
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

SH21A_HUMAN
NC score	0.066523 (rank : 188)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	400	Target Neighborhood Hits	89	Shared Neighborhood Hits	53
SwissProt Accessions	O60880, O95383, O95384, O95385, O95386, Q9UNR0	Gene names	SH2D1A, DSHP, SAP
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP) (Duncan disease SH2-protein).

ABL2_HUMAN
NC score	0.065610 (rank : 189)	θ value	0.47712 (rank : 96)
Query Neighborhood Hits	400	Target Neighborhood Hits	1045	Shared Neighborhood Hits	108
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

AUTS2_HUMAN
NC score	0.065494 (rank : 190)	θ value	2.36792 (rank : 191)
Query Neighborhood Hits	400	Target Neighborhood Hits	342	Shared Neighborhood Hits	62
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

SRMS_HUMAN
NC score	0.065430 (rank : 191)	θ value	0.0431538 (rank : 40)
Query Neighborhood Hits	400	Target Neighborhood Hits	946	Shared Neighborhood Hits	90
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

MLL2_HUMAN
NC score	0.065194 (rank : 192)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	400	Target Neighborhood Hits	1788	Shared Neighborhood Hits	155
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

SOCS1_MOUSE
NC score	0.065121 (rank : 193)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	400	Target Neighborhood Hits	82	Shared Neighborhood Hits	40
SwissProt Accessions	O35716, O35960, Q3U3L0	Gene names	Socs1, Cish1, Ssi1
Domain Architecture
Description	Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1).

RGS3_HUMAN
NC score	0.064902 (rank : 194)	θ value	5.27518 (rank : 328)
Query Neighborhood Hits	400	Target Neighborhood Hits	1375	Shared Neighborhood Hits	129
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

FYN_HUMAN
NC score	0.064848 (rank : 195)	θ value	0.0961366 (rank : 51)
Query Neighborhood Hits	400	Target Neighborhood Hits	1078	Shared Neighborhood Hits	95
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

APXL_HUMAN
NC score	0.064674 (rank : 196)	θ value	0.62314 (rank : 110)
Query Neighborhood Hits	400	Target Neighborhood Hits	553	Shared Neighborhood Hits	53
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

CPSF6_HUMAN
NC score	0.064671 (rank : 197)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	400	Target Neighborhood Hits	359	Shared Neighborhood Hits	73
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

SRC_MOUSE
NC score	0.064524 (rank : 198)	θ value	0.125558 (rank : 60)
Query Neighborhood Hits	400	Target Neighborhood Hits	1033	Shared Neighborhood Hits	94
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

YLPM1_HUMAN
NC score	0.064515 (rank : 199)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	400	Target Neighborhood Hits	670	Shared Neighborhood Hits	96
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

URFB1_HUMAN
NC score	0.064490 (rank : 200)	θ value	0.0961366 (rank : 55)
Query Neighborhood Hits	400	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	Q6BDS2, Q9NXE0	Gene names	UHRF1BP1, C6orf107
Domain Architecture	No domain graphic available
Description	UHRF1-binding protein 1 (Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1) (ICBP90-binding protein 1).

SFPQ_HUMAN
NC score	0.064459 (rank : 201)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	400	Target Neighborhood Hits	986	Shared Neighborhood Hits	116
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

ZIM10_HUMAN
NC score	0.064408 (rank : 202)	θ value	1.38821 (rank : 169)
Query Neighborhood Hits	400	Target Neighborhood Hits	577	Shared Neighborhood Hits	89
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

SRMS_MOUSE
NC score	0.064193 (rank : 203)	θ value	0.21417 (rank : 71)
Query Neighborhood Hits	400	Target Neighborhood Hits	964	Shared Neighborhood Hits	91
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

BASP_HUMAN
NC score	0.064052 (rank : 204)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	400	Target Neighborhood Hits	321	Shared Neighborhood Hits	41
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

AAK1_HUMAN
NC score	0.063820 (rank : 205)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	400	Target Neighborhood Hits	1077	Shared Neighborhood Hits	105
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

BTK_HUMAN
NC score	0.063037 (rank : 206)	θ value	2.36792 (rank : 196)
Query Neighborhood Hits	400	Target Neighborhood Hits	1026	Shared Neighborhood Hits	86
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

FGR_HUMAN
NC score	0.062933 (rank : 207)	θ value	1.81305 (rank : 175)
Query Neighborhood Hits	400	Target Neighborhood Hits	1067	Shared Neighborhood Hits	94
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

CIC_HUMAN
NC score	0.062929 (rank : 208)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	400	Target Neighborhood Hits	992	Shared Neighborhood Hits	127
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SRC_HUMAN
NC score	0.062928 (rank : 209)	θ value	1.06291 (rank : 150)
Query Neighborhood Hits	400	Target Neighborhood Hits	1058	Shared Neighborhood Hits	95
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

TARSH_HUMAN
NC score	0.062903 (rank : 210)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	400	Target Neighborhood Hits	768	Shared Neighborhood Hits	95
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

PTN6_MOUSE
NC score	0.062882 (rank : 211)	θ value	5.27518 (rank : 325)
Query Neighborhood Hits	400	Target Neighborhood Hits	225	Shared Neighborhood Hits	79
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

AAK1_MOUSE
NC score	0.062605 (rank : 212)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	400	Target Neighborhood Hits	1051	Shared Neighborhood Hits	100
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

BLK_MOUSE
NC score	0.062491 (rank : 213)	θ value	2.36792 (rank : 195)
Query Neighborhood Hits	400	Target Neighborhood Hits	992	Shared Neighborhood Hits	85
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

TXK_HUMAN
NC score	0.062204 (rank : 214)	θ value	2.36792 (rank : 228)
Query Neighborhood Hits	400	Target Neighborhood Hits	971	Shared Neighborhood Hits	87
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

TXK_MOUSE
NC score	0.062149 (rank : 215)	θ value	4.03905 (rank : 296)
Query Neighborhood Hits	400	Target Neighborhood Hits	980	Shared Neighborhood Hits	85
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

SF3A2_HUMAN
NC score	0.062057 (rank : 216)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	400	Target Neighborhood Hits	263	Shared Neighborhood Hits	56
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

PDZD2_HUMAN
NC score	0.062049 (rank : 217)	θ value	0.163984 (rank : 65)
Query Neighborhood Hits	400	Target Neighborhood Hits	772	Shared Neighborhood Hits	81
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

SET1A_HUMAN
NC score	0.061958 (rank : 218)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	400	Target Neighborhood Hits	690	Shared Neighborhood Hits	81
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

BTK_MOUSE
NC score	0.061939 (rank : 219)	θ value	4.03905 (rank : 262)
Query Neighborhood Hits	400	Target Neighborhood Hits	1017	Shared Neighborhood Hits	85
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

CPSF6_MOUSE
NC score	0.061907 (rank : 220)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	400	Target Neighborhood Hits	356	Shared Neighborhood Hits	72
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

MILK1_MOUSE
NC score	0.061801 (rank : 221)	θ value	2.36792 (rank : 212)
Query Neighborhood Hits	400	Target Neighborhood Hits	788	Shared Neighborhood Hits	101
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

WASF3_HUMAN
NC score	0.061594 (rank : 222)	θ value	0.813845 (rank : 136)
Query Neighborhood Hits	400	Target Neighborhood Hits	204	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

CRTC1_HUMAN
NC score	0.061547 (rank : 223)	θ value	5.27518 (rank : 311)
Query Neighborhood Hits	400	Target Neighborhood Hits	319	Shared Neighborhood Hits	76
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

LYN_MOUSE
NC score	0.061427 (rank : 224)	θ value	4.03905 (rank : 275)
Query Neighborhood Hits	400	Target Neighborhood Hits	1023	Shared Neighborhood Hits	90
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

R3HD2_MOUSE
NC score	0.061409 (rank : 225)	θ value	2.36792 (rank : 220)
Query Neighborhood Hits	400	Target Neighborhood Hits	397	Shared Neighborhood Hits	68
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

GGN_MOUSE
NC score	0.061168 (rank : 226)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	400	Target Neighborhood Hits	311	Shared Neighborhood Hits	69
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GRIN1_HUMAN
NC score	0.061148 (rank : 227)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	400	Target Neighborhood Hits	681	Shared Neighborhood Hits	101
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

SFPQ_MOUSE
NC score	0.061108 (rank : 228)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	400	Target Neighborhood Hits	958	Shared Neighborhood Hits	108
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SON_HUMAN
NC score	0.061026 (rank : 229)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	400	Target Neighborhood Hits	1568	Shared Neighborhood Hits	150
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

DGKK_HUMAN
NC score	0.060982 (rank : 230)	θ value	0.62314 (rank : 112)
Query Neighborhood Hits	400	Target Neighborhood Hits	378	Shared Neighborhood Hits	66
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

ZIM10_MOUSE
NC score	0.060692 (rank : 231)	θ value	2.36792 (rank : 229)
Query Neighborhood Hits	400	Target Neighborhood Hits	430	Shared Neighborhood Hits	77
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

K1802_HUMAN
NC score	0.060319 (rank : 232)	θ value	6.88961 (rank : 344)
Query Neighborhood Hits	400	Target Neighborhood Hits	1378	Shared Neighborhood Hits	122
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

PRG4_MOUSE
NC score	0.060302 (rank : 233)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	400	Target Neighborhood Hits	624	Shared Neighborhood Hits	75
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

YES_HUMAN
NC score	0.060259 (rank : 234)	θ value	4.03905 (rank : 299)
Query Neighborhood Hits	400	Target Neighborhood Hits	1059	Shared Neighborhood Hits	87
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

CNOT3_HUMAN
NC score	0.060182 (rank : 235)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	400	Target Neighborhood Hits	425	Shared Neighborhood Hits	63
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CK024_HUMAN
NC score	0.060163 (rank : 236)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	400	Target Neighborhood Hits	408	Shared Neighborhood Hits	65
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

YES_MOUSE
NC score	0.060141 (rank : 237)	θ value	4.03905 (rank : 300)
Query Neighborhood Hits	400	Target Neighborhood Hits	1052	Shared Neighborhood Hits	87
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

MLL3_MOUSE
NC score	0.059896 (rank : 238)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	400	Target Neighborhood Hits	1399	Shared Neighborhood Hits	129
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

HRX_HUMAN
NC score	0.059868 (rank : 239)	θ value	0.47712 (rank : 99)
Query Neighborhood Hits	400	Target Neighborhood Hits	825	Shared Neighborhood Hits	89
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

HCK_HUMAN
NC score	0.059836 (rank : 240)	θ value	4.03905 (rank : 272)
Query Neighborhood Hits	400	Target Neighborhood Hits	1035	Shared Neighborhood Hits	88
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

LYN_HUMAN
NC score	0.059796 (rank : 241)	θ value	6.88961 (rank : 345)
Query Neighborhood Hits	400	Target Neighborhood Hits	1022	Shared Neighborhood Hits	90
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

FYN_MOUSE
NC score	0.059775 (rank : 242)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	400	Target Neighborhood Hits	1073	Shared Neighborhood Hits	91
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

CCNK_MOUSE
NC score	0.059762 (rank : 243)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	400	Target Neighborhood Hits	350	Shared Neighborhood Hits	70
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

K1543_MOUSE
NC score	0.059563 (rank : 244)	θ value	2.36792 (rank : 205)
Query Neighborhood Hits	400	Target Neighborhood Hits	497	Shared Neighborhood Hits	73
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

PI5PA_HUMAN
NC score	0.059476 (rank : 245)	θ value	8.99809 (rank : 386)
Query Neighborhood Hits	400	Target Neighborhood Hits	749	Shared Neighborhood Hits	111
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

SOCS6_MOUSE
NC score	0.059426 (rank : 246)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	400	Target Neighborhood Hits	146	Shared Neighborhood Hits	57
SwissProt Accessions	Q9JLY0, Q9D2A0	Gene names	Socs6, Cis4, Cish4, Socs4
Domain Architecture
Description	Suppressor of cytokine signaling 6 (SOCS-6) (Suppressor of cytokine signaling 4) (SOCS-4) (Cytokine-inducible SH2 protein 4) (CIS-4).

HCK_MOUSE
NC score	0.059422 (rank : 247)	θ value	5.27518 (rank : 316)
Query Neighborhood Hits	400	Target Neighborhood Hits	1029	Shared Neighborhood Hits	86
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

BLNK_MOUSE
NC score	0.059283 (rank : 248)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	400	Target Neighborhood Hits	296	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

ZN750_MOUSE
NC score	0.059069 (rank : 249)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	400	Target Neighborhood Hits	346	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

MUC1_MOUSE
NC score	0.058979 (rank : 250)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	400	Target Neighborhood Hits	388	Shared Neighborhood Hits	52
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

MINT_MOUSE
NC score	0.058964 (rank : 251)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	400	Target Neighborhood Hits	1514	Shared Neighborhood Hits	136
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

T22D2_HUMAN
NC score	0.058905 (rank : 252)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	400	Target Neighborhood Hits	250	Shared Neighborhood Hits	62
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

PPRB_MOUSE
NC score	0.058866 (rank : 253)	θ value	2.36792 (rank : 218)
Query Neighborhood Hits	400	Target Neighborhood Hits	354	Shared Neighborhood Hits	65
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

APS_MOUSE
NC score	0.058750 (rank : 254)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	400	Target Neighborhood Hits	134	Shared Neighborhood Hits	56
SwissProt Accessions	Q9JID9, O88936	Gene names	Aps
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

VAV3_MOUSE
NC score	0.058641 (rank : 255)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	400	Target Neighborhood Hits	404	Shared Neighborhood Hits	78
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

MATK_MOUSE
NC score	0.058612 (rank : 256)	θ value	4.03905 (rank : 276)
Query Neighborhood Hits	400	Target Neighborhood Hits	952	Shared Neighborhood Hits	88
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

TEC_MOUSE
NC score	0.058594 (rank : 257)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	400	Target Neighborhood Hits	1006	Shared Neighborhood Hits	81
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TEC_HUMAN
NC score	0.058362 (rank : 258)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	400	Target Neighborhood Hits	1006	Shared Neighborhood Hits	82
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

MLL4_HUMAN
NC score	0.058306 (rank : 259)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	400	Target Neighborhood Hits	722	Shared Neighborhood Hits	93
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MTSS1_HUMAN
NC score	0.058292 (rank : 260)	θ value	0.62314 (rank : 114)
Query Neighborhood Hits	400	Target Neighborhood Hits	504	Shared Neighborhood Hits	57
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

CDN1C_HUMAN
NC score	0.058080 (rank : 261)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	400	Target Neighborhood Hits	168	Shared Neighborhood Hits	34
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

SOCS6_HUMAN
NC score	0.058009 (rank : 262)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	400	Target Neighborhood Hits	126	Shared Neighborhood Hits	53
SwissProt Accessions	O14544	Gene names	SOCS6, CIS4, SOCS4
Domain Architecture
Description	Suppressor of cytokine signaling 6 (SOCS-6) (Suppressor of cytokine signaling 4) (SOCS-4) (Cytokine-inducible SH2 protein 4) (CIS-4).

VAV3_HUMAN
NC score	0.057994 (rank : 263)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	400	Target Neighborhood Hits	398	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

EFS_HUMAN
NC score	0.057597 (rank : 264)	θ value	3.0926 (rank : 233)
Query Neighborhood Hits	400	Target Neighborhood Hits	348	Shared Neighborhood Hits	76
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

SMR3A_HUMAN
NC score	0.057422 (rank : 265)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	400	Target Neighborhood Hits	93	Shared Neighborhood Hits	26
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

PRPC_HUMAN
NC score	0.057407 (rank : 266)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	400	Target Neighborhood Hits	165	Shared Neighborhood Hits	37
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

MATK_HUMAN
NC score	0.057384 (rank : 267)	θ value	5.27518 (rank : 319)
Query Neighborhood Hits	400	Target Neighborhood Hits	954	Shared Neighborhood Hits	88
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

MTSS1_MOUSE
NC score	0.057241 (rank : 268)	θ value	1.81305 (rank : 180)
Query Neighborhood Hits	400	Target Neighborhood Hits	592	Shared Neighborhood Hits	70
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

BLK_HUMAN
NC score	0.057233 (rank : 269)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	400	Target Neighborhood Hits	994	Shared Neighborhood Hits	81
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

SC24A_MOUSE
NC score	0.057219 (rank : 270)	θ value	4.03905 (rank : 286)
Query Neighborhood Hits	400	Target Neighborhood Hits	394	Shared Neighborhood Hits	59
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

WASF2_MOUSE
NC score	0.057196 (rank : 271)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	400	Target Neighborhood Hits	315	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

LCK_MOUSE
NC score	0.057080 (rank : 272)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	400	Target Neighborhood Hits	981	Shared Neighborhood Hits	86
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

SH2D3_HUMAN
NC score	0.056762 (rank : 273)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	400	Target Neighborhood Hits	188	Shared Neighborhood Hits	66
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

PCQAP_HUMAN
NC score	0.056698 (rank : 274)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	400	Target Neighborhood Hits	549	Shared Neighborhood Hits	65
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

LCK_HUMAN
NC score	0.056523 (rank : 275)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	400	Target Neighborhood Hits	987	Shared Neighborhood Hits	86
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

BCAR3_HUMAN
NC score	0.056241 (rank : 276)	θ value	8.99809 (rank : 368)
Query Neighborhood Hits	400	Target Neighborhood Hits	129	Shared Neighborhood Hits	55
SwissProt Accessions	O75815, Q6UW40, Q9BR50	Gene names	BCAR3, NSP2, SH2D3B
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (SH2 domain- containing protein 3B) (Novel SH2-containing protein 2).

OGFR_MOUSE
NC score	0.055824 (rank : 277)	θ value	8.99809 (rank : 384)
Query Neighborhood Hits	400	Target Neighborhood Hits	584	Shared Neighborhood Hits	63
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

MAP4_MOUSE
NC score	0.055823 (rank : 278)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	400	Target Neighborhood Hits	409	Shared Neighborhood Hits	56
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

SH23A_HUMAN
NC score	0.055698 (rank : 279)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	400	Target Neighborhood Hits	149	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BRG2, Q9Y2X4	Gene names	SH2D3A, NSP1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3A (Novel SH2-containing protein 1).

PELP1_MOUSE
NC score	0.055652 (rank : 280)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	400	Target Neighborhood Hits	709	Shared Neighborhood Hits	99
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

SF3A2_MOUSE
NC score	0.055567 (rank : 281)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	400	Target Neighborhood Hits	247	Shared Neighborhood Hits	57
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

VAV_HUMAN
NC score	0.055444 (rank : 282)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	400	Target Neighborhood Hits	452	Shared Neighborhood Hits	75
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

GGN_HUMAN
NC score	0.055315 (rank : 283)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	400	Target Neighborhood Hits	269	Shared Neighborhood Hits	53
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

SNPC4_HUMAN
NC score	0.055240 (rank : 284)	θ value	2.36792 (rank : 224)
Query Neighborhood Hits	400	Target Neighborhood Hits	589	Shared Neighborhood Hits	85
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

PO121_HUMAN
NC score	0.055211 (rank : 285)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	400	Target Neighborhood Hits	344	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PTN6_HUMAN
NC score	0.055007 (rank : 286)	θ value	5.27518 (rank : 324)
Query Neighborhood Hits	400	Target Neighborhood Hits	234	Shared Neighborhood Hits	74
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

GPTC8_HUMAN
NC score	0.054986 (rank : 287)	θ value	0.813845 (rank : 120)
Query Neighborhood Hits	400	Target Neighborhood Hits	366	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

ITK_HUMAN
NC score	0.054915 (rank : 288)	θ value	3.0926 (rank : 241)
Query Neighborhood Hits	400	Target Neighborhood Hits	1016	Shared Neighborhood Hits	85
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

MILK1_HUMAN
NC score	0.054845 (rank : 289)	θ value	2.36792 (rank : 211)
Query Neighborhood Hits	400	Target Neighborhood Hits	427	Shared Neighborhood Hits	72
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

ITK_MOUSE
NC score	0.054808 (rank : 290)	θ value	4.03905 (rank : 273)
Query Neighborhood Hits	400	Target Neighborhood Hits	985	Shared Neighborhood Hits	82
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

MAML1_HUMAN
NC score	0.054445 (rank : 291)	θ value	6.88961 (rank : 346)
Query Neighborhood Hits	400	Target Neighborhood Hits	228	Shared Neighborhood Hits	41
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

SH2D3_MOUSE
NC score	0.054372 (rank : 292)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	400	Target Neighborhood Hits	174	Shared Neighborhood Hits	62
SwissProt Accessions	Q9QZS8, Q9JME1	Gene names	Sh2d3c, Chat, Shep1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (SH2 domain-containing Eph receptor- binding protein 1) (Cas/HEF1-associated signal transducer).

DIDO1_HUMAN
NC score	0.054185 (rank : 293)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	400	Target Neighborhood Hits	960	Shared Neighborhood Hits	102
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

FRK_HUMAN
NC score	0.054143 (rank : 294)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	400	Target Neighborhood Hits	1058	Shared Neighborhood Hits	91
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

TP53B_MOUSE
NC score	0.054082 (rank : 295)	θ value	4.03905 (rank : 295)
Query Neighborhood Hits	400	Target Neighborhood Hits	644	Shared Neighborhood Hits	67
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

PHLB1_MOUSE
NC score	0.054029 (rank : 296)	θ value	0.365318 (rank : 94)
Query Neighborhood Hits	400	Target Neighborhood Hits	678	Shared Neighborhood Hits	61
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

ZN207_HUMAN
NC score	0.053993 (rank : 297)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	400	Target Neighborhood Hits	326	Shared Neighborhood Hits	51
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

WBP11_HUMAN
NC score	0.053960 (rank : 298)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	400	Target Neighborhood Hits	354	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

TCOF_MOUSE
NC score	0.053871 (rank : 299)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	400	Target Neighborhood Hits	471	Shared Neighborhood Hits	62
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

SFR15_HUMAN
NC score	0.053643 (rank : 300)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	400	Target Neighborhood Hits	368	Shared Neighborhood Hits	60
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

CO039_MOUSE
NC score	0.053423 (rank : 301)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	400	Target Neighborhood Hits	445	Shared Neighborhood Hits	81
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

PHLB1_HUMAN
NC score	0.053387 (rank : 302)	θ value	0.365318 (rank : 93)
Query Neighborhood Hits	400	Target Neighborhood Hits	1038	Shared Neighborhood Hits	85
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

TTBK1_HUMAN
NC score	0.053345 (rank : 303)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	400	Target Neighborhood Hits	1058	Shared Neighborhood Hits	89
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

ZIMP7_MOUSE
NC score	0.053317 (rank : 304)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	400	Target Neighborhood Hits	566	Shared Neighborhood Hits	89
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

FA47B_HUMAN
NC score	0.053209 (rank : 305)	θ value	3.0926 (rank : 235)
Query Neighborhood Hits	400	Target Neighborhood Hits	431	Shared Neighborhood Hits	62
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

JPH2_HUMAN
NC score	0.053173 (rank : 306)	θ value	0.279714 (rank : 74)
Query Neighborhood Hits	400	Target Neighborhood Hits	639	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

BCAR3_MOUSE
NC score	0.053140 (rank : 307)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	400	Target Neighborhood Hits	127	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QZK2, Q3TNC9, Q3UP10	Gene names	Bcar3, And34
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (p130Cas-binding protein AND-34).

SYN3_MOUSE
NC score	0.053096 (rank : 308)	θ value	6.88961 (rank : 358)
Query Neighborhood Hits	400	Target Neighborhood Hits	200	Shared Neighborhood Hits	46
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

PIAS3_MOUSE
NC score	0.053006 (rank : 309)	θ value	0.00665767 (rank : 21)
Query Neighborhood Hits	400	Target Neighborhood Hits	65	Shared Neighborhood Hits	10
SwissProt Accessions	O54714, Q80WF8, Q8R598	Gene names	Pias3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

BCAR1_HUMAN
NC score	0.052741 (rank : 310)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	400	Target Neighborhood Hits	554	Shared Neighborhood Hits	107
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

EWS_MOUSE
NC score	0.052530 (rank : 311)	θ value	0.365318 (rank : 84)
Query Neighborhood Hits	400	Target Neighborhood Hits	271	Shared Neighborhood Hits	36
SwissProt Accessions	Q61545	Gene names	Ewsr1, Ews, Ewsh
Domain Architecture
Description	RNA-binding protein EWS.

PTK6_HUMAN
NC score	0.052466 (rank : 312)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	400	Target Neighborhood Hits	1020	Shared Neighborhood Hits	85
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

BMP2K_HUMAN
NC score	0.052345 (rank : 313)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	400	Target Neighborhood Hits	867	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NSY1, O94791, Q8IYF2, Q8N2G7, Q8NHG9, Q9NTG8	Gene names	BMP2K, BIKE
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

3BP1_HUMAN
NC score	0.051970 (rank : 314)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	400	Target Neighborhood Hits	376	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

PTK6_MOUSE
NC score	0.051876 (rank : 315)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	400	Target Neighborhood Hits	1026	Shared Neighborhood Hits	87
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

SHAN1_HUMAN
NC score	0.051827 (rank : 316)	θ value	2.36792 (rank : 223)
Query Neighborhood Hits	400	Target Neighborhood Hits	1041	Shared Neighborhood Hits	123
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

WASP_HUMAN
NC score	0.051485 (rank : 317)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	400	Target Neighborhood Hits	195	Shared Neighborhood Hits	49
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

AFF1_HUMAN
NC score	0.051451 (rank : 318)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	400	Target Neighborhood Hits	506	Shared Neighborhood Hits	72
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

SSBP4_HUMAN
NC score	0.051288 (rank : 319)	θ value	3.0926 (rank : 255)
Query Neighborhood Hits	400	Target Neighborhood Hits	753	Shared Neighborhood Hits	101
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

PCQAP_MOUSE
NC score	0.051156 (rank : 320)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	400	Target Neighborhood Hits	506	Shared Neighborhood Hits	62
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

SELV_HUMAN
NC score	0.051135 (rank : 321)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	400	Target Neighborhood Hits	118	Shared Neighborhood Hits	33
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

PRR13_HUMAN
NC score	0.050970 (rank : 322)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	400	Target Neighborhood Hits	105	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

GA2L2_MOUSE
NC score	0.050954 (rank : 323)	θ value	2.36792 (rank : 200)
Query Neighborhood Hits	400	Target Neighborhood Hits	395	Shared Neighborhood Hits	68
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

WASF1_HUMAN
NC score	0.050891 (rank : 324)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	400	Target Neighborhood Hits	260	Shared Neighborhood Hits	56
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

VAV_MOUSE
NC score	0.050698 (rank : 325)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	400	Target Neighborhood Hits	430	Shared Neighborhood Hits	72
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

WASF1_MOUSE
NC score	0.050267 (rank : 326)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	400	Target Neighborhood Hits	261	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

BMP2K_MOUSE
NC score	0.050197 (rank : 327)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	400	Target Neighborhood Hits	874	Shared Neighborhood Hits	48
SwissProt Accessions	Q91Z96, Q8C8L7	Gene names	Bmp2k, Bike
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

CIZ1_HUMAN
NC score	0.050027 (rank : 328)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	400	Target Neighborhood Hits	359	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

LR37A_HUMAN
NC score	0.049966 (rank : 329)	θ value	0.62314 (rank : 113)
Query Neighborhood Hits	400	Target Neighborhood Hits	720	Shared Neighborhood Hits	70
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

CHIO_HUMAN
NC score	0.049364 (rank : 330)	θ value	2.36792 (rank : 197)
Query Neighborhood Hits	400	Target Neighborhood Hits	220	Shared Neighborhood Hits	55
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

SYNG_MOUSE
NC score	0.049160 (rank : 331)	θ value	0.279714 (rank : 81)
Query Neighborhood Hits	400	Target Neighborhood Hits	206	Shared Neighborhood Hits	28
SwissProt Accessions	Q5SV85, Q5SV84, Q6PHT6	Gene names	Ap1gbp1, Syng
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

HORN_MOUSE
NC score	0.049126 (rank : 332)	θ value	0.813845 (rank : 123)
Query Neighborhood Hits	400	Target Neighborhood Hits	218	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

CHIN_MOUSE
NC score	0.048593 (rank : 333)	θ value	5.27518 (rank : 307)
Query Neighborhood Hits	400	Target Neighborhood Hits	229	Shared Neighborhood Hits	65
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

FER_HUMAN
NC score	0.048425 (rank : 334)	θ value	3.0926 (rank : 236)
Query Neighborhood Hits	400	Target Neighborhood Hits	1278	Shared Neighborhood Hits	93
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

K2002_MOUSE
NC score	0.048231 (rank : 335)	θ value	2.36792 (rank : 206)
Query Neighborhood Hits	400	Target Neighborhood Hits	267	Shared Neighborhood Hits	12
SwissProt Accessions	Q69Z38, Q8R365	Gene names	Kiaa2002
Domain Architecture	No domain graphic available
Description	Uncharacterized tyrosine-protein kinase KIAA2002 (EC 2.7.10.2).

ZCH14_HUMAN
NC score	0.048220 (rank : 336)	θ value	0.47712 (rank : 109)
Query Neighborhood Hits	400	Target Neighborhood Hits	117	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WYQ9, O60324, Q9UFP0	Gene names	ZCCHC14, KIAA0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

EWS_HUMAN
NC score	0.047961 (rank : 337)	θ value	1.38821 (rank : 156)
Query Neighborhood Hits	400	Target Neighborhood Hits	249	Shared Neighborhood Hits	35
SwissProt Accessions	Q01844, Q92635	Gene names	EWSR1, EWS
Domain Architecture
Description	RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein).

SEPT9_HUMAN
NC score	0.047840 (rank : 338)	θ value	1.38821 (rank : 163)
Query Neighborhood Hits	400	Target Neighborhood Hits	706	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

SMOO_HUMAN
NC score	0.047439 (rank : 339)	θ value	4.03905 (rank : 292)
Query Neighborhood Hits	400	Target Neighborhood Hits	391	Shared Neighborhood Hits	57
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

GAB2_MOUSE
NC score	0.047286 (rank : 340)	θ value	1.81305 (rank : 176)
Query Neighborhood Hits	400	Target Neighborhood Hits	220	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

TTBK2_MOUSE
NC score	0.047161 (rank : 341)	θ value	3.0926 (rank : 259)
Query Neighborhood Hits	400	Target Neighborhood Hits	811	Shared Neighborhood Hits	50
SwissProt Accessions	Q3UVR3, Q3TSR6, Q3UFW0, Q571D1, Q8BKA4, Q924U8	Gene names	Ttbk2, Kiaa0847, Ttbk1
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2.

YETS2_MOUSE
NC score	0.047156 (rank : 342)	θ value	0.62314 (rank : 118)
Query Neighborhood Hits	400	Target Neighborhood Hits	278	Shared Neighborhood Hits	39
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

TTBK2_HUMAN
NC score	0.047088 (rank : 343)	θ value	3.0926 (rank : 258)
Query Neighborhood Hits	400	Target Neighborhood Hits	822	Shared Neighborhood Hits	54
SwissProt Accessions	Q6IQ55, O94932, Q6ZN52, Q8IVV1	Gene names	TTBK2, KIAA0847
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2 (EC 2.7.11.1).

CO002_HUMAN
NC score	0.046857 (rank : 344)	θ value	8.99809 (rank : 373)
Query Neighborhood Hits	400	Target Neighborhood Hits	387	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

ASXL1_HUMAN
NC score	0.046773 (rank : 345)	θ value	0.365318 (rank : 82)
Query Neighborhood Hits	400	Target Neighborhood Hits	260	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

CO039_HUMAN
NC score	0.046584 (rank : 346)	θ value	5.27518 (rank : 310)
Query Neighborhood Hits	400	Target Neighborhood Hits	264	Shared Neighborhood Hits	49
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

CDSN_HUMAN
NC score	0.046439 (rank : 347)	θ value	1.81305 (rank : 172)
Query Neighborhood Hits	400	Target Neighborhood Hits	84	Shared Neighborhood Hits	19
SwissProt Accessions	Q15517, O43509, Q5SQ85, Q5STD2, Q7LA70, Q7LA71, Q86Z04, Q8IZU4, Q8IZU5, Q8IZU6, Q8N5P3, Q95IF9, Q9NP52, Q9NPE0, Q9NPG5, Q9NRH4, Q9NRH5, Q9NRH6, Q9NRH7, Q9NRH8, Q9UBH8, Q9UIN6, Q9UIN7, Q9UIN8, Q9UIN9, Q9UIP0	Gene names	CDSN
Domain Architecture	No domain graphic available
Description	Corneodesmosin precursor (S protein).

SYNPO_MOUSE
NC score	0.046242 (rank : 348)	θ value	5.27518 (rank : 329)
Query Neighborhood Hits	400	Target Neighborhood Hits	242	Shared Neighborhood Hits	48
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

UBE4B_HUMAN
NC score	0.046239 (rank : 349)	θ value	1.06291 (rank : 153)
Query Neighborhood Hits	400	Target Neighborhood Hits	158	Shared Neighborhood Hits	37
SwissProt Accessions	O95155, O75169, O95338, Q5SZ12, Q5SZ16, Q96QD4, Q9BYI7	Gene names	UBE4B, HDNB1, KIAA0684, UFD2
Domain Architecture
Description	Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Homozygously deleted in neuroblastoma 1).

SOX13_MOUSE
NC score	0.045895 (rank : 350)	θ value	0.0330416 (rank : 38)
Query Neighborhood Hits	400	Target Neighborhood Hits	495	Shared Neighborhood Hits	58
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

DOK1_HUMAN
NC score	0.045524 (rank : 351)	θ value	0.0431538 (rank : 39)
Query Neighborhood Hits	400	Target Neighborhood Hits	85	Shared Neighborhood Hits	10
SwissProt Accessions	Q99704, O43204, Q9UHG6	Gene names	DOK1
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)) (pp62).

ATX1_MOUSE
NC score	0.044989 (rank : 352)	θ value	1.38821 (rank : 154)
Query Neighborhood Hits	400	Target Neighborhood Hits	264	Shared Neighborhood Hits	40
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

GAB2_HUMAN
NC score	0.044955 (rank : 353)	θ value	1.38821 (rank : 157)
Query Neighborhood Hits	400	Target Neighborhood Hits	188	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

MAST4_HUMAN
NC score	0.044801 (rank : 354)	θ value	0.163984 (rank : 63)
Query Neighborhood Hits	400	Target Neighborhood Hits	1804	Shared Neighborhood Hits	155
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

AATK_HUMAN
NC score	0.044355 (rank : 355)	θ value	8.99809 (rank : 364)
Query Neighborhood Hits	400	Target Neighborhood Hits	1243	Shared Neighborhood Hits	112
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

JIP1_HUMAN
NC score	0.044342 (rank : 356)	θ value	2.36792 (rank : 204)
Query Neighborhood Hits	400	Target Neighborhood Hits	271	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

COHA1_HUMAN
NC score	0.044073 (rank : 357)	θ value	6.88961 (rank : 340)
Query Neighborhood Hits	400	Target Neighborhood Hits	400	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

ZCH14_MOUSE
NC score	0.043728 (rank : 358)	θ value	5.27518 (rank : 331)
Query Neighborhood Hits	400	Target Neighborhood Hits	109	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VIG0, Q80TX3, Q91VU4	Gene names	Zcchc14, Kiaa0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

MUC5B_HUMAN
NC score	0.043053 (rank : 359)	θ value	6.88961 (rank : 348)
Query Neighborhood Hits	400	Target Neighborhood Hits	1020	Shared Neighborhood Hits	91
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

TNR6A_HUMAN
NC score	0.042961 (rank : 360)	θ value	8.99809 (rank : 396)
Query Neighborhood Hits	400	Target Neighborhood Hits	343	Shared Neighborhood Hits	45
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

SRGP1_HUMAN
NC score	0.042804 (rank : 361)	θ value	0.279714 (rank : 78)
Query Neighborhood Hits	400	Target Neighborhood Hits	390	Shared Neighborhood Hits	48
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

RAI1_MOUSE
NC score	0.040586 (rank : 362)	θ value	4.03905 (rank : 280)
Query Neighborhood Hits	400	Target Neighborhood Hits	344	Shared Neighborhood Hits	54
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

CO4A5_HUMAN
NC score	0.040528 (rank : 363)	θ value	1.38821 (rank : 155)
Query Neighborhood Hits	400	Target Neighborhood Hits	383	Shared Neighborhood Hits	63
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

CO3A1_MOUSE
NC score	0.040495 (rank : 364)	θ value	3.0926 (rank : 232)
Query Neighborhood Hits	400	Target Neighborhood Hits	466	Shared Neighborhood Hits	70
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

PIAS3_HUMAN
NC score	0.039111 (rank : 365)	θ value	1.06291 (rank : 145)
Query Neighborhood Hits	400	Target Neighborhood Hits	58	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y6X2, Q9UFI3	Gene names	PIAS3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

CD2L7_HUMAN
NC score	0.038516 (rank : 366)	θ value	0.47712 (rank : 97)
Query Neighborhood Hits	400	Target Neighborhood Hits	1275	Shared Neighborhood Hits	99
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

REXO1_MOUSE
NC score	0.038498 (rank : 367)	θ value	1.06291 (rank : 146)
Query Neighborhood Hits	400	Target Neighborhood Hits	166	Shared Neighborhood Hits	24
SwissProt Accessions	Q7TT28, Q3UMP1, Q69ZR0, Q6NSQ6, Q6PI95, Q9DA29	Gene names	Rexo1, Kiaa1138, Tceb3bp1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1).

MAP1B_MOUSE
NC score	0.038432 (rank : 368)	θ value	0.813845 (rank : 124)
Query Neighborhood Hits	400	Target Neighborhood Hits	977	Shared Neighborhood Hits	62
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

ELN_HUMAN
NC score	0.037307 (rank : 369)	θ value	8.99809 (rank : 377)
Query Neighborhood Hits	400	Target Neighborhood Hits	85	Shared Neighborhood Hits	20
SwissProt Accessions	P15502, O15336, O15337, Q14233, Q14234, Q14235, Q14238, Q6P0L4, Q6ZWJ6, Q75MU5, Q7Z316, Q7Z3F5, Q9UMF5	Gene names	ELN
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

PCIF1_HUMAN
NC score	0.037262 (rank : 370)	θ value	0.47712 (rank : 105)
Query Neighborhood Hits	400	Target Neighborhood Hits	92	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H4Z3, Q9NT85	Gene names	PCIF1, C20orf67
Domain Architecture
Description	Phosphorylated CTD-interacting factor 1.

NSD1_MOUSE
NC score	0.036847 (rank : 371)	θ value	3.0926 (rank : 246)
Query Neighborhood Hits	400	Target Neighborhood Hits	472	Shared Neighborhood Hits	49
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

CO4A1_HUMAN
NC score	0.036587 (rank : 372)	θ value	0.279714 (rank : 73)
Query Neighborhood Hits	400	Target Neighborhood Hits	425	Shared Neighborhood Hits	75
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

NUP62_HUMAN
NC score	0.036473 (rank : 373)	θ value	3.0926 (rank : 248)
Query Neighborhood Hits	400	Target Neighborhood Hits	195	Shared Neighborhood Hits	17
SwissProt Accessions	P37198, Q503A4, Q96C43, Q9NSL1	Gene names	NUP62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

HXA3_MOUSE
NC score	0.036342 (rank : 374)	θ value	0.125558 (rank : 57)
Query Neighborhood Hits	400	Target Neighborhood Hits	558	Shared Neighborhood Hits	64
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

PROX1_MOUSE
NC score	0.035855 (rank : 375)	θ value	1.38821 (rank : 162)
Query Neighborhood Hits	400	Target Neighborhood Hits	184	Shared Neighborhood Hits	7
SwissProt Accessions	P48437, O88478, Q3UPV1, Q543D8	Gene names	Prox1
Domain Architecture
Description	Homeobox prospero-like protein PROX1 (PROX 1).

CO2A1_MOUSE
NC score	0.035758 (rank : 376)	θ value	1.81305 (rank : 174)
Query Neighborhood Hits	400	Target Neighborhood Hits	483	Shared Neighborhood Hits	68
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

PGCA_MOUSE
NC score	0.035303 (rank : 377)	θ value	0.813845 (rank : 131)
Query Neighborhood Hits	400	Target Neighborhood Hits	643	Shared Neighborhood Hits	61
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

LN28B_HUMAN
NC score	0.034959 (rank : 378)	θ value	1.06291 (rank : 139)
Query Neighborhood Hits	400	Target Neighborhood Hits	66	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZN17	Gene names	LIN28B, CSDD2
Domain Architecture	No domain graphic available
Description	Lin-28 homolog B.

CSKI1_HUMAN
NC score	0.034786 (rank : 379)	θ value	4.03905 (rank : 265)
Query Neighborhood Hits	400	Target Neighborhood Hits	997	Shared Neighborhood Hits	110
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

NCOA3_MOUSE
NC score	0.034728 (rank : 380)	θ value	0.62314 (rank : 115)
Query Neighborhood Hits	400	Target Neighborhood Hits	203	Shared Neighborhood Hits	43
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

OBSCN_HUMAN
NC score	0.034426 (rank : 381)	θ value	0.47712 (rank : 102)
Query Neighborhood Hits	400	Target Neighborhood Hits	1931	Shared Neighborhood Hits	131
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

GA2L1_HUMAN
NC score	0.034380 (rank : 382)	θ value	6.88961 (rank : 342)
Query Neighborhood Hits	400	Target Neighborhood Hits	177	Shared Neighborhood Hits	42
SwissProt Accessions	Q99501, Q53EN7, Q92640, Q9BUY9	Gene names	GAS2L1, GAR22
Domain Architecture
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1) (GAS2-related protein on chromosome 22) (GAR22 protein).

ANR38_MOUSE
NC score	0.034322 (rank : 383)	θ value	0.0148317 (rank : 23)
Query Neighborhood Hits	400	Target Neighborhood Hits	512	Shared Neighborhood Hits	25
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

TM16H_HUMAN
NC score	0.034245 (rank : 384)	θ value	2.36792 (rank : 227)
Query Neighborhood Hits	400	Target Neighborhood Hits	139	Shared Neighborhood Hits	23
SwissProt Accessions	Q9HCE9	Gene names	TMEM16H, KIAA1623
Domain Architecture	No domain graphic available
Description	Transmembrane protein 16H.

DBNL_MOUSE
NC score	0.033948 (rank : 385)	θ value	4.03905 (rank : 266)
Query Neighborhood Hits	400	Target Neighborhood Hits	306	Shared Neighborhood Hits	44
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

ALMS1_MOUSE
NC score	0.033912 (rank : 386)	θ value	2.36792 (rank : 189)
Query Neighborhood Hits	400	Target Neighborhood Hits	181	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K4E0, Q6A084, Q8C9N9	Gene names	Alms1, Kiaa0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1 homolog.

HGS_HUMAN
NC score	0.033878 (rank : 387)	θ value	1.38821 (rank : 158)
Query Neighborhood Hits	400	Target Neighborhood Hits	517	Shared Neighborhood Hits	52
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

GA2L1_MOUSE
NC score	0.033455 (rank : 388)	θ value	5.27518 (rank : 314)
Query Neighborhood Hits	400	Target Neighborhood Hits	114	Shared Neighborhood Hits	26
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

PHAR3_MOUSE
NC score	0.033200 (rank : 389)	θ value	1.81305 (rank : 181)
Query Neighborhood Hits	400	Target Neighborhood Hits	206	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BYK5, Q8BYS8, Q8C058, Q9DB87	Gene names	Phactr3, Scapin1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

PO6F2_HUMAN
NC score	0.032977 (rank : 390)	θ value	8.99809 (rank : 388)
Query Neighborhood Hits	400	Target Neighborhood Hits	618	Shared Neighborhood Hits	77
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

PROX1_HUMAN
NC score	0.032923 (rank : 391)	θ value	2.36792 (rank : 219)
Query Neighborhood Hits	400	Target Neighborhood Hits	171	Shared Neighborhood Hits	6
SwissProt Accessions	Q92786, Q5SW76, Q8TB91	Gene names	PROX1
Domain Architecture
Description	Homeobox prospero-like protein PROX1 (PROX 1).

ATX7_HUMAN
NC score	0.032890 (rank : 392)	θ value	5.27518 (rank : 305)
Query Neighborhood Hits	400	Target Neighborhood Hits	351	Shared Neighborhood Hits	52
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

CO4A1_MOUSE
NC score	0.032644 (rank : 393)	θ value	8.99809 (rank : 374)
Query Neighborhood Hits	400	Target Neighborhood Hits	450	Shared Neighborhood Hits	72
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

MK15_HUMAN
NC score	0.032466 (rank : 394)	θ value	1.38821 (rank : 160)
Query Neighborhood Hits	400	Target Neighborhood Hits	1038	Shared Neighborhood Hits	82
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

ES8L2_MOUSE
NC score	0.032137 (rank : 395)	θ value	8.99809 (rank : 378)
Query Neighborhood Hits	400	Target Neighborhood Hits	169	Shared Neighborhood Hits	42
SwissProt Accessions	Q99K30, Q91VT7	Gene names	Eps8l2, Eps8r2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

WDR33_HUMAN
NC score	0.031911 (rank : 396)	θ value	4.03905 (rank : 297)
Query Neighborhood Hits	400	Target Neighborhood Hits	638	Shared Neighborhood Hits	61
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

DEN1A_HUMAN
NC score	0.031753 (rank : 397)	θ value	0.62314 (rank : 111)
Query Neighborhood Hits	400	Target Neighborhood Hits	176	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

NFIB_HUMAN
NC score	0.031462 (rank : 398)	θ value	0.62314 (rank : 116)
Query Neighborhood Hits	400	Target Neighborhood Hits	66	Shared Neighborhood Hits	18
SwissProt Accessions	O00712, O00166, Q12858, Q96J45	Gene names	NFIB
Domain Architecture
Description	Nuclear factor 1 B-type (Nuclear factor 1/B) (NF1-B) (NFI-B) (NF-I/B) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

PODXL_MOUSE
NC score	0.031437 (rank : 399)	θ value	8.99809 (rank : 389)
Query Neighborhood Hits	400	Target Neighborhood Hits	130	Shared Neighborhood Hits	26
SwissProt Accessions	Q9R0M4, Q9ESZ1	Gene names	Podxl, Pclp1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

HXA3_HUMAN
NC score	0.031252 (rank : 400)	θ value	0.365318 (rank : 86)
Query Neighborhood Hits	400	Target Neighborhood Hits	535	Shared Neighborhood Hits	56
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

DOCK4_HUMAN
NC score	0.030865 (rank : 401)	θ value	1.06291 (rank : 138)
Query Neighborhood Hits	400	Target Neighborhood Hits	237	Shared Neighborhood Hits	42
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

PCDH7_HUMAN
NC score	0.030677 (rank : 402)	θ value	0.0148317 (rank : 27)
Query Neighborhood Hits	400	Target Neighborhood Hits	175	Shared Neighborhood Hits	15
SwissProt Accessions	O60245, O60246, O60247	Gene names	PCDH7, BHPCDH
Domain Architecture
Description	Protocadherin-7 precursor (Brain-heart protocadherin) (BH-Pcdh).

NFIB_MOUSE
NC score	0.030634 (rank : 403)	θ value	1.38821 (rank : 161)
Query Neighborhood Hits	400	Target Neighborhood Hits	72	Shared Neighborhood Hits	19
SwissProt Accessions	P97863, P70252, P70253, P70254, Q9R1G4	Gene names	Nfib
Domain Architecture
Description	Nuclear factor 1 B-type (Nuclear factor 1/B) (NF1-B) (NFI-B) (NF-I/B) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

MAST3_HUMAN
NC score	0.030555 (rank : 404)	θ value	2.36792 (rank : 209)
Query Neighborhood Hits	400	Target Neighborhood Hits	1128	Shared Neighborhood Hits	89
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

STAT1_MOUSE
NC score	0.030507 (rank : 405)	θ value	0.279714 (rank : 80)
Query Neighborhood Hits	400	Target Neighborhood Hits	151	Shared Neighborhood Hits	10
SwissProt Accessions	P42225	Gene names	Stat1
Domain Architecture
Description	Signal transducer and activator of transcription 1.

STAT1_HUMAN
NC score	0.030341 (rank : 406)	θ value	0.279714 (rank : 79)
Query Neighborhood Hits	400	Target Neighborhood Hits	128	Shared Neighborhood Hits	11
SwissProt Accessions	P42224	Gene names	STAT1
Domain Architecture
Description	Signal transducer and activator of transcription 1-alpha/beta (Transcription factor ISGF-3 components p91/p84).

TBCD2_HUMAN
NC score	0.029892 (rank : 407)	θ value	0.813845 (rank : 135)
Query Neighborhood Hits	400	Target Neighborhood Hits	419	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

NPAS4_HUMAN
NC score	0.029591 (rank : 408)	θ value	3.0926 (rank : 245)
Query Neighborhood Hits	400	Target Neighborhood Hits	214	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

BRSK1_HUMAN
NC score	0.029522 (rank : 409)	θ value	8.99809 (rank : 369)
Query Neighborhood Hits	400	Target Neighborhood Hits	942	Shared Neighborhood Hits	67
SwissProt Accessions	Q8TDC3, Q5J5B5, Q8NDD0, Q8NDR4, Q8TDC2, Q96AV4, Q96JL4	Gene names	BRSK1, KIAA1811, SAD1
Domain Architecture
Description	BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1 kinase) (SAD1A).

B3A3_HUMAN
NC score	0.029486 (rank : 410)	θ value	0.0736092 (rank : 46)
Query Neighborhood Hits	400	Target Neighborhood Hits	119	Shared Neighborhood Hits	25
SwissProt Accessions	P48751	Gene names	SLC4A3, AE3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3) (Cardiac/brain band 3-like protein) (CAE3/BAE3).

TRIM8_MOUSE
NC score	0.029432 (rank : 411)	θ value	0.0961366 (rank : 54)
Query Neighborhood Hits	400	Target Neighborhood Hits	674	Shared Neighborhood Hits	30
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

PCDA1_HUMAN
NC score	0.029291 (rank : 412)	θ value	0.0193708 (rank : 29)
Query Neighborhood Hits	400	Target Neighborhood Hits	199	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y5I3, O75288, Q9NRT7	Gene names	PCDHA1
Domain Architecture
Description	Protocadherin alpha 1 precursor (PCDH-alpha1).

DOCK4_MOUSE
NC score	0.028738 (rank : 413)	θ value	2.36792 (rank : 198)
Query Neighborhood Hits	400	Target Neighborhood Hits	210	Shared Neighborhood Hits	33
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

MEGF9_MOUSE
NC score	0.028722 (rank : 414)	θ value	2.36792 (rank : 210)
Query Neighborhood Hits	400	Target Neighborhood Hits	896	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

RNPS1_HUMAN
NC score	0.028634 (rank : 415)	θ value	4.03905 (rank : 282)
Query Neighborhood Hits	400	Target Neighborhood Hits	285	Shared Neighborhood Hits	20
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
NC score	0.028634 (rank : 416)	θ value	4.03905 (rank : 283)
Query Neighborhood Hits	400	Target Neighborhood Hits	285	Shared Neighborhood Hits	20
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

REPS1_HUMAN
NC score	0.028253 (rank : 417)	θ value	1.81305 (rank : 183)
Query Neighborhood Hits	400	Target Neighborhood Hits	205	Shared Neighborhood Hits	22
SwissProt Accessions	Q96D71, Q8NDR7, Q8WU62, Q9BXY9	Gene names	REPS1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

X3CL1_HUMAN
NC score	0.027624 (rank : 418)	θ value	4.03905 (rank : 298)
Query Neighborhood Hits	400	Target Neighborhood Hits	152	Shared Neighborhood Hits	22
SwissProt Accessions	P78423, O00672	Gene names	CX3CL1, A-152E5.2, FKN, NTT, SCYD1
Domain Architecture
Description	Fractalkine precursor (CX3CL1) (Neurotactin) (CX3C membrane-anchored chemokine) (Small inducible cytokine D1).

PCDA4_HUMAN
NC score	0.027428 (rank : 419)	θ value	0.125558 (rank : 58)
Query Neighborhood Hits	400	Target Neighborhood Hits	193	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UN74, O75285	Gene names	PCDHA4
Domain Architecture
Description	Protocadherin alpha 4 precursor (PCDH-alpha4).

CGRE1_HUMAN
NC score	0.027288 (rank : 420)	θ value	8.99809 (rank : 370)
Query Neighborhood Hits	400	Target Neighborhood Hits	354	Shared Neighborhood Hits	31
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

YAP1_HUMAN
NC score	0.027168 (rank : 421)	θ value	6.88961 (rank : 361)
Query Neighborhood Hits	400	Target Neighborhood Hits	173	Shared Neighborhood Hits	35
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

M4K4_MOUSE
NC score	0.027165 (rank : 422)	θ value	2.36792 (rank : 208)
Query Neighborhood Hits	400	Target Neighborhood Hits	1560	Shared Neighborhood Hits	73
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

RBM15_HUMAN
NC score	0.026998 (rank : 423)	θ value	3.0926 (rank : 254)
Query Neighborhood Hits	400	Target Neighborhood Hits	309	Shared Neighborhood Hits	24
SwissProt Accessions	Q96T37, Q5D058, Q96PE4, Q96SC5, Q96SC6, Q96SC9, Q96SD0, Q96T38, Q9BRA5, Q9H6R8, Q9H9Y0	Gene names	RBM15, OTT
Domain Architecture
Description	Putative RNA-binding protein 15 (RNA-binding motif protein 15) (One- twenty two protein).

KCNH6_HUMAN
NC score	0.026718 (rank : 424)	θ value	0.0330416 (rank : 37)
Query Neighborhood Hits	400	Target Neighborhood Hits	222	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

MYCB2_MOUSE
NC score	0.026691 (rank : 425)	θ value	2.36792 (rank : 213)
Query Neighborhood Hits	400	Target Neighborhood Hits	307	Shared Neighborhood Hits	32
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

ASTL_HUMAN
NC score	0.026595 (rank : 426)	θ value	5.27518 (rank : 304)
Query Neighborhood Hits	400	Target Neighborhood Hits	252	Shared Neighborhood Hits	42
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

CO8A2_MOUSE
NC score	0.026367 (rank : 427)	θ value	6.88961 (rank : 339)
Query Neighborhood Hits	400	Target Neighborhood Hits	273	Shared Neighborhood Hits	50
SwissProt Accessions	P25318, Q68ED0, Q6KAQ4, Q6P1C4	Gene names	Col8a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

PCD12_HUMAN
NC score	0.026332 (rank : 428)	θ value	0.279714 (rank : 76)
Query Neighborhood Hits	400	Target Neighborhood Hits	203	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NPG4, Q6UXB6, Q96KB8, Q9H7Y6, Q9H8E0	Gene names	PCDH12
Domain Architecture
Description	Protocadherin-12 precursor (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cadherin-2) (VE-cad-2).

NP1L3_MOUSE
NC score	0.026098 (rank : 429)	θ value	1.06291 (rank : 142)
Query Neighborhood Hits	400	Target Neighborhood Hits	233	Shared Neighborhood Hits	15
SwissProt Accessions	Q794H2, O54802	Gene names	Nap1l3, Mb20
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 3 (Brain-specific protein MB20).

PCDAD_HUMAN
NC score	0.026043 (rank : 430)	θ value	0.365318 (rank : 92)
Query Neighborhood Hits	400	Target Neighborhood Hits	197	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y5I0, O75277	Gene names	PCDHA13
Domain Architecture
Description	Protocadherin alpha 13 precursor (PCDH-alpha13).

PCDA9_HUMAN
NC score	0.026042 (rank : 431)	θ value	0.813845 (rank : 130)
Query Neighborhood Hits	400	Target Neighborhood Hits	203	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y5H5, O15053	Gene names	PCDHA9, KIAA0345
Domain Architecture
Description	Protocadherin alpha 9 precursor (PCDH-alpha9).

PCDH1_HUMAN
NC score	0.025977 (rank : 432)	θ value	0.47712 (rank : 104)
Query Neighborhood Hits	400	Target Neighborhood Hits	174	Shared Neighborhood Hits	14
SwissProt Accessions	Q08174	Gene names	PCDH1
Domain Architecture
Description	Protocadherin-1 precursor (Protocadherin-42) (PC42) (Cadherin-like protein 1).

PSMF1_MOUSE
NC score	0.025566 (rank : 433)	θ value	3.0926 (rank : 251)
Query Neighborhood Hits	400	Target Neighborhood Hits	85	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BHL8, Q8C0G9	Gene names	Psmf1
Domain Architecture	No domain graphic available
Description	Proteasome inhibitor PI31 subunit.

CD248_HUMAN
NC score	0.025550 (rank : 434)	θ value	4.03905 (rank : 263)
Query Neighborhood Hits	400	Target Neighborhood Hits	679	Shared Neighborhood Hits	62
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

PML_HUMAN
NC score	0.025496 (rank : 435)	θ value	3.0926 (rank : 250)
Query Neighborhood Hits	400	Target Neighborhood Hits	248	Shared Neighborhood Hits	19
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

SEPT9_MOUSE
NC score	0.024912 (rank : 436)	θ value	1.81305 (rank : 184)
Query Neighborhood Hits	400	Target Neighborhood Hits	238	Shared Neighborhood Hits	27
SwissProt Accessions	Q80UG5, Q3URP2, Q80TM7, Q9QYX9	Gene names	Sept9, Kiaa0991, Sint1
Domain Architecture	No domain graphic available
Description	Septin-9 (SL3-3 integration site 1 protein).

PCD12_MOUSE
NC score	0.024293 (rank : 437)	θ value	3.0926 (rank : 249)
Query Neighborhood Hits	400	Target Neighborhood Hits	199	Shared Neighborhood Hits	15
SwissProt Accessions	O55134	Gene names	Pcdh12
Domain Architecture
Description	Protocadherin-12 precursor (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cadherin-2) (VE-cad-2).

TULP4_HUMAN
NC score	0.024126 (rank : 438)	θ value	8.99809 (rank : 397)
Query Neighborhood Hits	400	Target Neighborhood Hits	426	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

TRIM8_HUMAN
NC score	0.024046 (rank : 439)	θ value	1.06291 (rank : 152)
Query Neighborhood Hits	400	Target Neighborhood Hits	650	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

ZC3H6_MOUSE
NC score	0.023910 (rank : 440)	θ value	1.81305 (rank : 187)
Query Neighborhood Hits	400	Target Neighborhood Hits	239	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

REPS1_MOUSE
NC score	0.023720 (rank : 441)	θ value	6.88961 (rank : 354)
Query Neighborhood Hits	400	Target Neighborhood Hits	204	Shared Neighborhood Hits	24
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

NELF_MOUSE
NC score	0.022918 (rank : 442)	θ value	3.0926 (rank : 243)
Query Neighborhood Hits	400	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q99NF2, Q8BPT0, Q8C9R5, Q9DBF4, Q9ERZ1	Gene names	Nelf, Jac
Domain Architecture	No domain graphic available
Description	Nasal embryonic luteinizing hormone-releasing hormone factor (Nasal embryonic LHRH factor) (Juxtasynaptic attractor of caldendrin on dendritic boutons protein) (Jacob protein).

HTF4_HUMAN
NC score	0.022856 (rank : 443)	θ value	1.81305 (rank : 177)
Query Neighborhood Hits	400	Target Neighborhood Hits	152	Shared Neighborhood Hits	15
SwissProt Accessions	Q99081	Gene names	TCF12, HEB, HTF4
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4).

NF1_HUMAN
NC score	0.022825 (rank : 444)	θ value	0.813845 (rank : 127)
Query Neighborhood Hits	400	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	P21359, O00662, Q14284, Q14930, Q9UMK3	Gene names	NF1
Domain Architecture
Description	Neurofibromin (Neurofibromatosis-related protein NF-1) [Contains: Neurofibromin truncated].

ADDB_MOUSE
NC score	0.022664 (rank : 445)	θ value	8.99809 (rank : 366)
Query Neighborhood Hits	400	Target Neighborhood Hits	574	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

AFF3_HUMAN
NC score	0.022527 (rank : 446)	θ value	4.03905 (rank : 260)
Query Neighborhood Hits	400	Target Neighborhood Hits	190	Shared Neighborhood Hits	23
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

BAT4_MOUSE
NC score	0.022251 (rank : 447)	θ value	3.0926 (rank : 230)
Query Neighborhood Hits	400	Target Neighborhood Hits	171	Shared Neighborhood Hits	13
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

SOX30_MOUSE
NC score	0.022160 (rank : 448)	θ value	8.99809 (rank : 394)
Query Neighborhood Hits	400	Target Neighborhood Hits	374	Shared Neighborhood Hits	48
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

LATS2_MOUSE
NC score	0.021663 (rank : 449)	θ value	0.0252991 (rank : 34)
Query Neighborhood Hits	400	Target Neighborhood Hits	879	Shared Neighborhood Hits	49
SwissProt Accessions	Q7TSJ6, Q8CDJ4, Q9JMI3	Gene names	Lats2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein).

FOG1_MOUSE
NC score	0.021410 (rank : 450)	θ value	3.0926 (rank : 237)
Query Neighborhood Hits	400	Target Neighborhood Hits	1237	Shared Neighborhood Hits	106
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

FOXK1_MOUSE
NC score	0.021405 (rank : 451)	θ value	0.21417 (rank : 68)
Query Neighborhood Hits	400	Target Neighborhood Hits	215	Shared Neighborhood Hits	26
SwissProt Accessions	P42128, O35939	Gene names	Foxk1, Mnf
Domain Architecture
Description	Forkhead box protein K1 (Myocyte nuclear factor) (MNF).

CMGA_MOUSE
NC score	0.021289 (rank : 452)	θ value	8.99809 (rank : 372)
Query Neighborhood Hits	400	Target Neighborhood Hits	172	Shared Neighborhood Hits	16
SwissProt Accessions	P26339	Gene names	Chga
Domain Architecture
Description	Chromogranin A precursor (CgA) [Contains: Pancreastatin; Beta-granin; WE-14].

ATBF1_MOUSE
NC score	0.021066 (rank : 453)	θ value	8.99809 (rank : 367)
Query Neighborhood Hits	400	Target Neighborhood Hits	1841	Shared Neighborhood Hits	125
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CSPG3_MOUSE
NC score	0.021049 (rank : 454)	θ value	1.06291 (rank : 137)
Query Neighborhood Hits	400	Target Neighborhood Hits	657	Shared Neighborhood Hits	52
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

IL2RB_MOUSE
NC score	0.020937 (rank : 455)	θ value	3.0926 (rank : 240)
Query Neighborhood Hits	400	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	P16297, Q3TZT2	Gene names	Il2rb
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).

P3C2A_MOUSE
NC score	0.020729 (rank : 456)	θ value	0.813845 (rank : 128)
Query Neighborhood Hits	400	Target Neighborhood Hits	181	Shared Neighborhood Hits	20
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

HXB3_HUMAN
NC score	0.020582 (rank : 457)	θ value	3.0926 (rank : 239)
Query Neighborhood Hits	400	Target Neighborhood Hits	559	Shared Neighborhood Hits	51
SwissProt Accessions	P14651, O95615, P17484	Gene names	HOXB3, HOX2G
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2G) (Hox-2.7).

SFTPD_MOUSE
NC score	0.020291 (rank : 458)	θ value	6.88961 (rank : 356)
Query Neighborhood Hits	400	Target Neighborhood Hits	217	Shared Neighborhood Hits	29
SwissProt Accessions	P50404	Gene names	Sftpd, Sftp4
Domain Architecture
Description	Pulmonary surfactant-associated protein D precursor (SP-D) (PSP-D).

RHG25_MOUSE
NC score	0.020237 (rank : 459)	θ value	8.99809 (rank : 392)
Query Neighborhood Hits	400	Target Neighborhood Hits	492	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

SPAG5_MOUSE
NC score	0.019842 (rank : 460)	θ value	1.06291 (rank : 149)
Query Neighborhood Hits	400	Target Neighborhood Hits	612	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

PLXB1_HUMAN
NC score	0.019551 (rank : 461)	θ value	4.03905 (rank : 278)
Query Neighborhood Hits	400	Target Neighborhood Hits	360	Shared Neighborhood Hits	46
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

RXRB_HUMAN
NC score	0.019477 (rank : 462)	θ value	4.03905 (rank : 284)
Query Neighborhood Hits	400	Target Neighborhood Hits	280	Shared Neighborhood Hits	52
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

NFAC4_HUMAN
NC score	0.018751 (rank : 463)	θ value	5.27518 (rank : 322)
Query Neighborhood Hits	400	Target Neighborhood Hits	165	Shared Neighborhood Hits	24
SwissProt Accessions	Q14934	Gene names	NFATC4, NFAT3
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T cell transcription factor NFAT3) (NF-AT3).

ANXA7_HUMAN
NC score	0.018420 (rank : 464)	θ value	2.36792 (rank : 190)
Query Neighborhood Hits	400	Target Neighborhood Hits	168	Shared Neighborhood Hits	32
SwissProt Accessions	P20073	Gene names	ANXA7, ANX7, SNX
Domain Architecture
Description	Annexin A7 (Annexin VII) (Synexin).

CEP35_HUMAN
NC score	0.018323 (rank : 465)	θ value	5.27518 (rank : 306)
Query Neighborhood Hits	400	Target Neighborhood Hits	811	Shared Neighborhood Hits	27
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

RIMB2_MOUSE
NC score	0.018309 (rank : 466)	θ value	8.99809 (rank : 393)
Query Neighborhood Hits	400	Target Neighborhood Hits	246	Shared Neighborhood Hits	28
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

TFE2_HUMAN
NC score	0.018232 (rank : 467)	θ value	6.88961 (rank : 359)
Query Neighborhood Hits	400	Target Neighborhood Hits	161	Shared Neighborhood Hits	20
SwissProt Accessions	P15923, P15883, Q14208, Q14635, Q14636, Q9UPI9	Gene names	TCF3, E2A, ITF1
Domain Architecture
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Immunoglobulin transcription factor 1) (Transcription factor ITF-1) (Kappa-E2-binding factor).

PSD4_HUMAN
NC score	0.017670 (rank : 468)	θ value	8.99809 (rank : 390)
Query Neighborhood Hits	400	Target Neighborhood Hits	178	Shared Neighborhood Hits	27
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

PTPRG_MOUSE
NC score	0.017185 (rank : 469)	θ value	1.81305 (rank : 182)
Query Neighborhood Hits	400	Target Neighborhood Hits	260	Shared Neighborhood Hits	22
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

KS6C1_HUMAN
NC score	0.017038 (rank : 470)	θ value	5.27518 (rank : 317)
Query Neighborhood Hits	400	Target Neighborhood Hits	682	Shared Neighborhood Hits	31
SwissProt Accessions	Q96S38, Q8TDD3, Q9NSF4, Q9UL66	Gene names	RPS6KC1, RPK118
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein).

GGA1_HUMAN
NC score	0.016937 (rank : 471)	θ value	4.03905 (rank : 268)
Query Neighborhood Hits	400	Target Neighborhood Hits	169	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

RBM14_HUMAN
NC score	0.016709 (rank : 472)	θ value	4.03905 (rank : 281)
Query Neighborhood Hits	400	Target Neighborhood Hits	213	Shared Neighborhood Hits	17
SwissProt Accessions	Q96PK6, O75932, Q53GV1, Q68DQ9, Q96PK5	Gene names	RBM14, SIP
Domain Architecture	No domain graphic available
Description	RNA-binding protein 14 (RNA-binding motif protein 14) (RRM-containing coactivator activator/modulator) (Synaptotagmin-interacting protein) (SYT-interacting protein).

RXRB_MOUSE
NC score	0.016271 (rank : 473)	θ value	4.03905 (rank : 285)
Query Neighborhood Hits	400	Target Neighborhood Hits	230	Shared Neighborhood Hits	44
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

QSCN6_HUMAN
NC score	0.016164 (rank : 474)	θ value	3.0926 (rank : 253)
Query Neighborhood Hits	400	Target Neighborhood Hits	98	Shared Neighborhood Hits	12
SwissProt Accessions	O00391, Q59G29, Q5T2X0, Q8TDL6, Q8WVP4	Gene names	QSCN6, QSOX1
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 1 precursor (EC 1.8.3.2) (Quiescin Q6) (hQSOX).

HXA4_HUMAN
NC score	0.016138 (rank : 475)	θ value	1.81305 (rank : 178)
Query Neighborhood Hits	400	Target Neighborhood Hits	370	Shared Neighborhood Hits	33
SwissProt Accessions	Q00056, O43366	Gene names	HOXA4, HOX1D
Domain Architecture
Description	Homeobox protein Hox-A4 (Hox-1D) (Hox-1.4).

CECR6_MOUSE
NC score	0.016083 (rank : 476)	θ value	6.88961 (rank : 337)
Query Neighborhood Hits	400	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q99MX7	Gene names	Cecr6
Domain Architecture	No domain graphic available
Description	Cat eye syndrome critical region protein 6 homolog.

MPDZ_MOUSE
NC score	0.016061 (rank : 477)	θ value	1.06291 (rank : 140)
Query Neighborhood Hits	400	Target Neighborhood Hits	298	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

OTX1_HUMAN
NC score	0.015890 (rank : 478)	θ value	2.36792 (rank : 214)
Query Neighborhood Hits	400	Target Neighborhood Hits	379	Shared Neighborhood Hits	23
SwissProt Accessions	P32242, Q53TG6	Gene names	OTX1
Domain Architecture
Description	Homeobox protein OTX1.

OTX1_MOUSE
NC score	0.015611 (rank : 479)	θ value	2.36792 (rank : 215)
Query Neighborhood Hits	400	Target Neighborhood Hits	372	Shared Neighborhood Hits	20
SwissProt Accessions	P80205	Gene names	Otx1, Otx-1
Domain Architecture
Description	Homeobox protein OTX1.

P3C2A_HUMAN
NC score	0.015491 (rank : 480)	θ value	6.88961 (rank : 351)
Query Neighborhood Hits	400	Target Neighborhood Hits	188	Shared Neighborhood Hits	17
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

GPR37_HUMAN
NC score	0.015453 (rank : 481)	θ value	0.0563607 (rank : 41)
Query Neighborhood Hits	400	Target Neighborhood Hits	584	Shared Neighborhood Hits	9
SwissProt Accessions	O15354, O00348, O14768, Q8TD39	Gene names	GPR37
Domain Architecture
Description	Probable G-protein coupled receptor 37 precursor (Endothelin B receptor-like protein 1) (ETBR-LP-1) (Parkin-associated endothelin receptor-like receptor) (PAELR).

PUM1_MOUSE
NC score	0.015313 (rank : 482)	θ value	4.03905 (rank : 279)
Query Neighborhood Hits	400	Target Neighborhood Hits	47	Shared Neighborhood Hits	9
SwissProt Accessions	Q80U78, Q80X96, Q80YU8, Q8BPV7, Q9EPU6	Gene names	Pum1, Kiaa0099
Domain Architecture
Description	Pumilio homolog 1.

RBM14_MOUSE
NC score	0.015152 (rank : 483)	θ value	5.27518 (rank : 327)
Query Neighborhood Hits	400	Target Neighborhood Hits	217	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C2Q3, Q3TJB6, Q91Z21, Q9DBI6	Gene names	Rbm14
Domain Architecture	No domain graphic available
Description	RNA-binding protein 14 (RNA-binding motif protein 14).

TNFC_MOUSE
NC score	0.014938 (rank : 484)	θ value	6.88961 (rank : 360)
Query Neighborhood Hits	400	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	P41155	Gene names	Ltb, Tnfc, Tnfsf3
Domain Architecture
Description	Lymphotoxin-beta (LT-beta) (Tumor necrosis factor C) (TNF-C) (Tumor necrosis factor ligand superfamily member 3).

DSG1C_MOUSE
NC score	0.014873 (rank : 485)	θ value	4.03905 (rank : 267)
Query Neighborhood Hits	400	Target Neighborhood Hits	156	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TSF0, Q7TQ61	Gene names	Dsg1c, Dsg6
Domain Architecture	No domain graphic available
Description	Desmoglein-1 gamma precursor (Dsg1-gamma) (Desmoglein-6).

BFSP2_MOUSE
NC score	0.014871 (rank : 486)	θ value	0.365318 (rank : 83)
Query Neighborhood Hits	400	Target Neighborhood Hits	423	Shared Neighborhood Hits	12
SwissProt Accessions	Q6NVD9, Q63832, Q6P5N4, Q8VDD6	Gene names	Bfsp2
Domain Architecture	No domain graphic available
Description	Phakinin (Beaded filament structural protein 2) (Lens fiber cell beaded filament protein CP 49) (CP49) (49 kDa cytoskeletal protein).

MEFV_HUMAN
NC score	0.014587 (rank : 487)	θ value	0.813845 (rank : 125)
Query Neighborhood Hits	400	Target Neighborhood Hits	431	Shared Neighborhood Hits	36
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

LY75_MOUSE
NC score	0.014400 (rank : 488)	θ value	1.81305 (rank : 179)
Query Neighborhood Hits	400	Target Neighborhood Hits	155	Shared Neighborhood Hits	6
SwissProt Accessions	Q60767, Q8C7T3, Q91XL8, Q9QUZ6	Gene names	Ly75, Cd205
Domain Architecture
Description	Lymphocyte antigen 75 precursor (DEC-205) (CD205 antigen).

TSH3_MOUSE
NC score	0.014267 (rank : 489)	θ value	3.0926 (rank : 257)
Query Neighborhood Hits	400	Target Neighborhood Hits	590	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CGV9, Q5DTX4	Gene names	Tshz3, Kiaa1474, Tsh3, Zfp537, Znf537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

TLE1_MOUSE
NC score	0.014235 (rank : 490)	θ value	2.36792 (rank : 226)
Query Neighborhood Hits	400	Target Neighborhood Hits	491	Shared Neighborhood Hits	46
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

FOXO1_MOUSE
NC score	0.013873 (rank : 491)	θ value	2.36792 (rank : 199)
Query Neighborhood Hits	400	Target Neighborhood Hits	118	Shared Neighborhood Hits	12
SwissProt Accessions	Q9R1E0	Gene names	Foxo1a, Fkhr, Foxo1
Domain Architecture
Description	Forkhead box protein O1A (Forkhead in rhabdomyosarcoma).

PABP1_HUMAN
NC score	0.013862 (rank : 492)	θ value	2.36792 (rank : 216)
Query Neighborhood Hits	400	Target Neighborhood Hits	269	Shared Neighborhood Hits	17
SwissProt Accessions	P11940, Q15097, Q93004	Gene names	PABPC1, PAB1, PABP1, PABPC2
Domain Architecture
Description	Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1).

ZEP1_MOUSE
NC score	0.013813 (rank : 493)	θ value	4.03905 (rank : 301)
Query Neighborhood Hits	400	Target Neighborhood Hits	1063	Shared Neighborhood Hits	73
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

PABP1_MOUSE
NC score	0.013648 (rank : 494)	θ value	2.36792 (rank : 217)
Query Neighborhood Hits	400	Target Neighborhood Hits	278	Shared Neighborhood Hits	17
SwissProt Accessions	P29341	Gene names	Pabpc1, Pabp1
Domain Architecture
Description	Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1).

BTBD7_HUMAN
NC score	0.013377 (rank : 495)	θ value	6.88961 (rank : 336)
Query Neighborhood Hits	400	Target Neighborhood Hits	176	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P203, Q69Z05, Q7Z308, Q86TS0, Q9HAA4, Q9NVM0	Gene names	BTBD7, KIAA1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

ETV5_MOUSE
NC score	0.013136 (rank : 496)	θ value	6.88961 (rank : 341)
Query Neighborhood Hits	400	Target Neighborhood Hits	328	Shared Neighborhood Hits	39
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

NRG2_HUMAN
NC score	0.013091 (rank : 497)	θ value	6.88961 (rank : 350)
Query Neighborhood Hits	400	Target Neighborhood Hits	419	Shared Neighborhood Hits	20
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

SIG10_HUMAN
NC score	0.013038 (rank : 498)	θ value	4.03905 (rank : 291)
Query Neighborhood Hits	400	Target Neighborhood Hits	363	Shared Neighborhood Hits	27
SwissProt Accessions	Q96LC7, Q6UXI8, Q96G54, Q96LC8	Gene names	SIGLEC10, SLG2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 10 precursor (Siglec-10) (Siglec- like protein 2).

PVRL2_HUMAN
NC score	0.013013 (rank : 499)	θ value	3.0926 (rank : 252)
Query Neighborhood Hits	400	Target Neighborhood Hits	185	Shared Neighborhood Hits	5
SwissProt Accessions	Q92692, O75455, Q96J29	Gene names	PVRL2, HVEB, PRR2
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Herpes virus entry mediator B) (HveB) (Nectin-2) (CD112 antigen).

CLCN1_HUMAN
NC score	0.012876 (rank : 500)	θ value	3.0926 (rank : 231)
Query Neighborhood Hits	400	Target Neighborhood Hits	89	Shared Neighborhood Hits	11
SwissProt Accessions	P35523	Gene names	CLCN1, CLC1
Domain Architecture
Description	Chloride channel protein, skeletal muscle (Chloride channel protein 1) (ClC-1).

SYTL5_HUMAN
NC score	0.012388 (rank : 501)	θ value	8.99809 (rank : 395)
Query Neighborhood Hits	400	Target Neighborhood Hits	237	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

STAB1_HUMAN
NC score	0.012002 (rank : 502)	θ value	0.62314 (rank : 117)
Query Neighborhood Hits	400	Target Neighborhood Hits	546	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

GOGA1_HUMAN
NC score	0.011850 (rank : 503)	θ value	0.365318 (rank : 85)
Query Neighborhood Hits	400	Target Neighborhood Hits	1222	Shared Neighborhood Hits	30
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GLE1_MOUSE
NC score	0.011750 (rank : 504)	θ value	8.99809 (rank : 379)
Query Neighborhood Hits	400	Target Neighborhood Hits	504	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

ANKS6_MOUSE
NC score	0.011734 (rank : 505)	θ value	5.27518 (rank : 303)
Query Neighborhood Hits	400	Target Neighborhood Hits	435	Shared Neighborhood Hits	29
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

CJ006_MOUSE
NC score	0.011569 (rank : 506)	θ value	8.99809 (rank : 371)
Query Neighborhood Hits	400	Target Neighborhood Hits	141	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P9P0, Q8C041, Q8C0J5	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf6 homolog.

SREC_HUMAN
NC score	0.011568 (rank : 507)	θ value	1.81305 (rank : 186)
Query Neighborhood Hits	400	Target Neighborhood Hits	645	Shared Neighborhood Hits	32
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

NKX26_MOUSE
NC score	0.011135 (rank : 508)	θ value	3.0926 (rank : 244)
Query Neighborhood Hits	400	Target Neighborhood Hits	343	Shared Neighborhood Hits	17
SwissProt Accessions	P43688	Gene names	Nkx2-6, Nkx-2.6, Nkx2f
Domain Architecture
Description	Homeobox protein Nkx-2.6 (Homeobox protein NK-2 homolog F).

UBAP1_HUMAN
NC score	0.010977 (rank : 509)	θ value	8.99809 (rank : 398)
Query Neighborhood Hits	400	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZ09, Q4V759, Q5T7B3, Q6FI75, Q8NC52, Q8NCG6, Q8NCH9	Gene names	UBAP1
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 1 (UBAP).

REV1_HUMAN
NC score	0.010940 (rank : 510)	θ value	8.99809 (rank : 391)
Query Neighborhood Hits	400	Target Neighborhood Hits	56	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UBZ9, O95941, Q9C0J4, Q9NUP2	Gene names	REV1L, REV1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase) (Alpha integrin-binding protein 80) (AIBP80).

CTTB2_HUMAN
NC score	0.010731 (rank : 511)	θ value	8.99809 (rank : 375)
Query Neighborhood Hits	400	Target Neighborhood Hits	1061	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

CDX4_HUMAN
NC score	0.010575 (rank : 512)	θ value	4.03905 (rank : 264)
Query Neighborhood Hits	400	Target Neighborhood Hits	366	Shared Neighborhood Hits	19
SwissProt Accessions	O14627, Q5JS20	Gene names	CDX4
Domain Architecture
Description	Homeobox protein CDX-4 (Caudal-type homeobox protein 4).

IMMT_MOUSE
NC score	0.010408 (rank : 513)	θ value	8.99809 (rank : 382)
Query Neighborhood Hits	400	Target Neighborhood Hits	326	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CAQ8, Q66JS4, Q7TNE2, Q8C7V1, Q8CCI0, Q8CDA8, Q9D9F6	Gene names	Immt
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin).

OTX2_HUMAN
NC score	0.010368 (rank : 514)	θ value	8.99809 (rank : 385)
Query Neighborhood Hits	400	Target Neighborhood Hits	341	Shared Neighborhood Hits	18
SwissProt Accessions	P32243, Q6GTV3, Q9HAW3, Q9P2R1	Gene names	OTX2
Domain Architecture
Description	Homeobox protein OTX2.

MCR_MOUSE
NC score	0.010202 (rank : 515)	θ value	4.03905 (rank : 277)
Query Neighborhood Hits	400	Target Neighborhood Hits	162	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

UBP10_MOUSE
NC score	0.010044 (rank : 516)	θ value	8.99809 (rank : 399)
Query Neighborhood Hits	400	Target Neighborhood Hits	150	Shared Neighborhood Hits	13
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

SENP1_MOUSE
NC score	0.010016 (rank : 517)	θ value	6.88961 (rank : 355)
Query Neighborhood Hits	400	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	P59110	Gene names	Senp1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

SP7_HUMAN
NC score	0.009902 (rank : 518)	θ value	0.125558 (rank : 59)
Query Neighborhood Hits	400	Target Neighborhood Hits	734	Shared Neighborhood Hits	28
SwissProt Accessions	Q8TDD2	Gene names	SP7, OSX
Domain Architecture	No domain graphic available
Description	Transcription factor Sp7 (Zinc finger protein osterix).

GP124_MOUSE
NC score	0.009887 (rank : 519)	θ value	4.03905 (rank : 269)
Query Neighborhood Hits	400	Target Neighborhood Hits	423	Shared Neighborhood Hits	24
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

SP7_MOUSE
NC score	0.009648 (rank : 520)	θ value	0.279714 (rank : 77)
Query Neighborhood Hits	400	Target Neighborhood Hits	756	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VI67, Q8C5R3, Q8C6A7	Gene names	Sp7, Osx
Domain Architecture	No domain graphic available
Description	Transcription factor Sp7 (Zinc finger protein osterix) (C22).

NUMA1_HUMAN
NC score	0.009383 (rank : 521)	θ value	3.0926 (rank : 247)
Query Neighborhood Hits	400	Target Neighborhood Hits	1523	Shared Neighborhood Hits	45
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

NRDC_MOUSE
NC score	0.009280 (rank : 522)	θ value	6.88961 (rank : 349)
Query Neighborhood Hits	400	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHG1	Gene names	Nrd1
Domain Architecture
Description	Nardilysin precursor (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C).

TBL1R_MOUSE
NC score	0.008989 (rank : 523)	θ value	1.38821 (rank : 167)
Query Neighborhood Hits	400	Target Neighborhood Hits	329	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BHJ5, Q3UWL6, Q8CBG4, Q8VEG3, Q9EQD4	Gene names	Tbl1xr1, Ira1, Tblr1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1).

TBL1R_HUMAN
NC score	0.008974 (rank : 524)	θ value	1.38821 (rank : 166)
Query Neighborhood Hits	400	Target Neighborhood Hits	327	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BZK7, Q9H2I1, Q9H9A1	Gene names	TBL1XR1, IRA1, TBLR1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1).

HLXB9_MOUSE
NC score	0.008546 (rank : 525)	θ value	8.99809 (rank : 380)
Query Neighborhood Hits	400	Target Neighborhood Hits	354	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QZW9	Gene names	Hlxb9
Domain Architecture
Description	Homeobox protein HB9.

ADA12_MOUSE
NC score	0.008279 (rank : 526)	θ value	8.99809 (rank : 365)
Query Neighborhood Hits	400	Target Neighborhood Hits	474	Shared Neighborhood Hits	46
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

CHIT1_HUMAN
NC score	0.007702 (rank : 527)	θ value	5.27518 (rank : 308)
Query Neighborhood Hits	400	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q13231, Q3ZAR1, Q6ISC2, Q9H3V8	Gene names	CHIT1
Domain Architecture
Description	Chitotriosidase-1 precursor (EC 3.2.1.14) (Chitinase-1).

PKP4_MOUSE
NC score	0.007691 (rank : 528)	θ value	8.99809 (rank : 387)
Query Neighborhood Hits	400	Target Neighborhood Hits	129	Shared Neighborhood Hits	15
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

ACHA4_HUMAN
NC score	0.007599 (rank : 529)	θ value	5.27518 (rank : 302)
Query Neighborhood Hits	400	Target Neighborhood Hits	131	Shared Neighborhood Hits	15
SwissProt Accessions	P43681, Q4JGR7	Gene names	CHRNA4, NACRA4
Domain Architecture
Description	Neuronal acetylcholine receptor protein subunit alpha-4 precursor.

BC11A_MOUSE
NC score	0.007498 (rank : 530)	θ value	2.36792 (rank : 194)
Query Neighborhood Hits	400	Target Neighborhood Hits	732	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QYE3, Q80T89, Q8BLC7, Q8BLR4, Q8BWX3, Q921V4, Q9D0V2, Q9JIT4, Q9JLK8, Q9JLK9	Gene names	Bcl11a, Ctip1, Evi9, Kiaa1809
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11A (B-cell CLL/lymphoma 11A) (COUP-TF- interacting protein 1) (Ecotropic viral integration site 9 protein) (EVI-9).

TCPZ_HUMAN
NC score	0.007407 (rank : 531)	θ value	4.03905 (rank : 294)
Query Neighborhood Hits	400	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	P40227, Q75LP4, Q96S46	Gene names	CCT6A, CCT6, CCTZ
Domain Architecture
Description	T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) (CCT-zeta-1) (Tcp20) (HTR3) (Acute morphine dependence-related protein 2).

CING_HUMAN
NC score	0.007088 (rank : 532)	θ value	5.27518 (rank : 309)
Query Neighborhood Hits	400	Target Neighborhood Hits	1275	Shared Neighborhood Hits	37
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

ABCA7_HUMAN
NC score	0.006541 (rank : 533)	θ value	2.36792 (rank : 188)
Query Neighborhood Hits	400	Target Neighborhood Hits	144	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IZY2, Q96S58, Q9BZC4, Q9NR73, Q9UKP8	Gene names	ABCA7
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 7 (Macrophage ABC transporter) (Autoantigen SS-N) (ABCA-SSN).

BC11A_HUMAN
NC score	0.005805 (rank : 534)	θ value	2.36792 (rank : 193)
Query Neighborhood Hits	400	Target Neighborhood Hits	745	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H165, Q86W14, Q8WU92, Q96JL6, Q9H163, Q9H164, Q9H3G9, Q9NWA7	Gene names	BCL11A, CTIP1, EVI9, KIAA1809
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11A (B-cell CLL/lymphoma 11A) (COUP-TF- interacting protein 1) (Ecotropic viral integration site 9 protein) (EVI-9).

RARA_HUMAN
NC score	0.005447 (rank : 535)	θ value	6.88961 (rank : 352)
Query Neighborhood Hits	400	Target Neighborhood Hits	118	Shared Neighborhood Hits	8
SwissProt Accessions	P10276, P78456, Q13440, Q13441, Q9NQS0	Gene names	RARA, NR1B1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARA_MOUSE
NC score	0.005370 (rank : 536)	θ value	6.88961 (rank : 353)
Query Neighborhood Hits	400	Target Neighborhood Hits	113	Shared Neighborhood Hits	6
SwissProt Accessions	P11416, P22603	Gene names	Rara, Nr1b1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

ZIC5_HUMAN
NC score	0.005320 (rank : 537)	θ value	1.38821 (rank : 168)
Query Neighborhood Hits	400	Target Neighborhood Hits	774	Shared Neighborhood Hits	37
SwissProt Accessions	Q96T25	Gene names	ZIC5
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZIC 5 (Zinc finger protein of the cerebellum 5).

ADAM9_MOUSE
NC score	0.004992 (rank : 538)	θ value	6.88961 (rank : 333)
Query Neighborhood Hits	400	Target Neighborhood Hits	325	Shared Neighborhood Hits	27
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ANR50_HUMAN
NC score	0.003999 (rank : 539)	θ value	6.88961 (rank : 334)
Query Neighborhood Hits	400	Target Neighborhood Hits	361	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

LRIG1_MOUSE
NC score	0.002787 (rank : 540)	θ value	2.36792 (rank : 207)
Query Neighborhood Hits	400	Target Neighborhood Hits	627	Shared Neighborhood Hits	14
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

CO2_HUMAN
NC score	0.002085 (rank : 541)	θ value	6.88961 (rank : 338)
Query Neighborhood Hits	400	Target Neighborhood Hits	258	Shared Neighborhood Hits	6
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

MTR1L_HUMAN
NC score	0.002070 (rank : 542)	θ value	5.27518 (rank : 320)
Query Neighborhood Hits	400	Target Neighborhood Hits	1180	Shared Neighborhood Hits	51
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

BCL6_HUMAN
NC score	0.000883 (rank : 543)	θ value	1.81305 (rank : 171)
Query Neighborhood Hits	400	Target Neighborhood Hits	922	Shared Neighborhood Hits	39
SwissProt Accessions	P41182	Gene names	BCL6, BCL5, LAZ3, ZBTB27, ZNF51
Domain Architecture
Description	B-cell lymphoma 6 protein (BCL-6) (Zinc finger protein 51) (LAZ-3 protein) (BCL-5) (Zinc finger and BTB domain-containing protein 27).

ZIC1_HUMAN
NC score	0.000672 (rank : 544)	θ value	5.27518 (rank : 332)
Query Neighborhood Hits	400	Target Neighborhood Hits	710	Shared Neighborhood Hits	18
SwissProt Accessions	Q15915	Gene names	ZIC1, ZIC
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZIC 1 (Zinc finger protein of the cerebellum 1).

EVI1_HUMAN
NC score	0.000355 (rank : 545)	θ value	5.27518 (rank : 313)
Query Neighborhood Hits	400	Target Neighborhood Hits	924	Shared Neighborhood Hits	34
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.

PLAL1_HUMAN
NC score	0.000340 (rank : 546)	θ value	5.27518 (rank : 323)
Query Neighborhood Hits	400	Target Neighborhood Hits	728	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UM63	Gene names	PLAGL1
Domain Architecture	No domain graphic available
Description	Zinc finger protein PLAGL1 (Pleiomorphic adenoma-like protein 1).

ZIC1_MOUSE
NC score	0.000238 (rank : 547)	θ value	8.99809 (rank : 400)
Query Neighborhood Hits	400	Target Neighborhood Hits	716	Shared Neighborhood Hits	20
SwissProt Accessions	P46684	Gene names	Zic1, Zic
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZIC 1 (Zinc finger protein of the cerebellum 1).

HMCN1_HUMAN
NC score	-0.000069 (rank : 548)	θ value	8.99809 (rank : 381)
Query Neighborhood Hits	400	Target Neighborhood Hits	983	Shared Neighborhood Hits	20
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

ZNF24_MOUSE
NC score	-0.001552 (rank : 549)	θ value	6.88961 (rank : 363)
Query Neighborhood Hits	400	Target Neighborhood Hits	717	Shared Neighborhood Hits	18
SwissProt Accessions	Q91VN1, Q9WUQ0	Gene names	Znf24, Zfp191
Domain Architecture
Description	Zinc finger protein 24 (Zinc finger protein 191) (Zfp-191) (Zinc finger protein ZF-12).

GP132_MOUSE
NC score	-0.001721 (rank : 550)	θ value	6.88961 (rank : 343)
Query Neighborhood Hits	400	Target Neighborhood Hits	488	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z282, Q3U5A4	Gene names	Gpr132, G2a
Domain Architecture
Description	Probable G-protein coupled receptor 132 (G2 accumulation protein).

ZN167_HUMAN
NC score	-0.003202 (rank : 551)	θ value	6.88961 (rank : 362)
Query Neighborhood Hits	400	Target Neighborhood Hits	784	Shared Neighborhood Hits	22
SwissProt Accessions	Q9P0L1, Q6WL09, Q96FQ2	Gene names	ZNF167, ZNF448, ZNF64
Domain Architecture	No domain graphic available
Description	Zinc finger protein 167 (Zinc finger protein 64) (Zinc finger protein 448) (ZFP).