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Network neighborhood for query Sequence : P3C2A_MOUSE

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P3C2A_MOUSE
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

P3C2A_HUMAN
θ value	0 (rank : 1)	NC score	0.995555 (rank : 2)
Query Neighborhood Hits	181	Target Neighborhood Hits	188	Shared Neighborhood Hits	138
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

P3C2A_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	181	Target Neighborhood Hits	181	Shared Neighborhood Hits	181
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

P3C2B_HUMAN
θ value	0 (rank : 3)	NC score	0.980410 (rank : 3)
Query Neighborhood Hits	181	Target Neighborhood Hits	148	Shared Neighborhood Hits	111
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

P3C2G_HUMAN
θ value	0 (rank : 4)	NC score	0.906437 (rank : 5)
Query Neighborhood Hits	181	Target Neighborhood Hits	92	Shared Neighborhood Hits	70
SwissProt Accessions	O75747	Gene names	PIK3C2G
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

P3C2G_MOUSE
θ value	0 (rank : 5)	NC score	0.916833 (rank : 4)
Query Neighborhood Hits	181	Target Neighborhood Hits	113	Shared Neighborhood Hits	87
SwissProt Accessions	O70167, O70168	Gene names	Pik3c2g
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

PK3CG_MOUSE
θ value	6.90186e-109 (rank : 6)	NC score	0.837133 (rank : 7)
Query Neighborhood Hits	181	Target Neighborhood Hits	43	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JHG7	Gene names	Pik3cg, Pi3kg1
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PK3CG_HUMAN
θ value	3.42535e-108 (rank : 7)	NC score	0.837909 (rank : 6)
Query Neighborhood Hits	181	Target Neighborhood Hits	41	Shared Neighborhood Hits	28
SwissProt Accessions	P48736, Q8IV23, Q9BZC8	Gene names	PIK3CG
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PK3CA_HUMAN
θ value	3.78717e-107 (rank : 8)	NC score	0.835068 (rank : 9)
Query Neighborhood Hits	181	Target Neighborhood Hits	45	Shared Neighborhood Hits	28
SwissProt Accessions	P42336, Q99762	Gene names	PIK3CA
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

PK3CA_MOUSE
θ value	6.45994e-107 (rank : 9)	NC score	0.835124 (rank : 8)
Query Neighborhood Hits	181	Target Neighborhood Hits	48	Shared Neighborhood Hits	28
SwissProt Accessions	P42337	Gene names	Pik3ca
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

PK3CB_MOUSE
θ value	1.26366e-94 (rank : 10)	NC score	0.822820 (rank : 12)
Query Neighborhood Hits	181	Target Neighborhood Hits	49	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BTI9	Gene names	Pik3cb
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

PK3CB_HUMAN
θ value	2.15548e-94 (rank : 11)	NC score	0.822657 (rank : 13)
Query Neighborhood Hits	181	Target Neighborhood Hits	43	Shared Neighborhood Hits	28
SwissProt Accessions	P42338	Gene names	PIK3CB
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

PK3CD_HUMAN
θ value	2.15548e-94 (rank : 12)	NC score	0.825653 (rank : 10)
Query Neighborhood Hits	181	Target Neighborhood Hits	40	Shared Neighborhood Hits	28
SwissProt Accessions	O00329, O15445	Gene names	PIK3CD
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

PK3CD_MOUSE
θ value	2.38316e-93 (rank : 13)	NC score	0.825167 (rank : 11)
Query Neighborhood Hits	181	Target Neighborhood Hits	42	Shared Neighborhood Hits	28
SwissProt Accessions	O35904	Gene names	Pik3cd
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

PK3C3_HUMAN
θ value	1.73182e-43 (rank : 14)	NC score	0.763152 (rank : 14)
Query Neighborhood Hits	181	Target Neighborhood Hits	49	Shared Neighborhood Hits	28
SwissProt Accessions	Q8NEB9, Q15134	Gene names	PIK3C3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3) (Phosphatidylinositol 3-kinase p100 subunit).

PK3C3_MOUSE
θ value	2.95404e-43 (rank : 15)	NC score	0.762026 (rank : 15)
Query Neighborhood Hits	181	Target Neighborhood Hits	49	Shared Neighborhood Hits	28
SwissProt Accessions	Q6PF93, Q8R3S8	Gene names	Pik3c3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3).

PI4KA_HUMAN
θ value	3.06405e-32 (rank : 16)	NC score	0.732404 (rank : 16)
Query Neighborhood Hits	181	Target Neighborhood Hits	53	Shared Neighborhood Hits	28
SwissProt Accessions	P42356, Q7Z625, Q9UPG2	Gene names	PIK4CA, PIK4
Domain Architecture
Description	Phosphatidylinositol 4-kinase alpha (EC 2.7.1.67) (PI4-kinase alpha) (PtdIns-4-kinase alpha) (PI4K-alpha).

PI4KB_HUMAN
θ value	4.43474e-23 (rank : 17)	NC score	0.685129 (rank : 18)
Query Neighborhood Hits	181	Target Neighborhood Hits	79	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UBF8, O15096, P78405, Q9BWR6	Gene names	PIK4CB, PI4KB
Domain Architecture
Description	Phosphatidylinositol 4-kinase beta (EC 2.7.1.67) (PtdIns 4-kinase beta) (PI4Kbeta) (PI4K-beta) (NPIK) (PI4K92).

PI4KB_MOUSE
θ value	7.56453e-23 (rank : 18)	NC score	0.686058 (rank : 17)
Query Neighborhood Hits	181	Target Neighborhood Hits	67	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BKC8, Q8C146	Gene names	Pik4cb
Domain Architecture
Description	Phosphatidylinositol 4-kinase beta (EC 2.7.1.67) (PtdIns 4-kinase beta) (PI4Kbeta) (PI4K-beta).

SYTL5_HUMAN
θ value	2.20605e-14 (rank : 19)	NC score	0.469191 (rank : 24)
Query Neighborhood Hits	181	Target Neighborhood Hits	237	Shared Neighborhood Hits	78
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

PCLO_HUMAN
θ value	2.88119e-14 (rank : 20)	NC score	0.319409 (rank : 69)
Query Neighborhood Hits	181	Target Neighborhood Hits	2046	Shared Neighborhood Hits	111
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SYTL4_HUMAN
θ value	3.76295e-14 (rank : 21)	NC score	0.472449 (rank : 21)
Query Neighborhood Hits	181	Target Neighborhood Hits	138	Shared Neighborhood Hits	74
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL1_MOUSE
θ value	4.91457e-14 (rank : 22)	NC score	0.457092 (rank : 25)
Query Neighborhood Hits	181	Target Neighborhood Hits	314	Shared Neighborhood Hits	76
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

SYTL4_MOUSE
θ value	1.42992e-13 (rank : 23)	NC score	0.470263 (rank : 22)
Query Neighborhood Hits	181	Target Neighborhood Hits	137	Shared Neighborhood Hits	75
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

FA62A_MOUSE
θ value	2.43908e-13 (rank : 24)	NC score	0.426297 (rank : 34)
Query Neighborhood Hits	181	Target Neighborhood Hits	155	Shared Neighborhood Hits	76
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

SYTL1_HUMAN
θ value	3.18553e-13 (rank : 25)	NC score	0.472706 (rank : 20)
Query Neighborhood Hits	181	Target Neighborhood Hits	227	Shared Neighborhood Hits	82
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

SYTL5_MOUSE
θ value	5.43371e-13 (rank : 26)	NC score	0.469542 (rank : 23)
Query Neighborhood Hits	181	Target Neighborhood Hits	154	Shared Neighborhood Hits	76
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SYT7_MOUSE
θ value	9.26847e-13 (rank : 27)	NC score	0.428274 (rank : 33)
Query Neighborhood Hits	181	Target Neighborhood Hits	137	Shared Neighborhood Hits	75
SwissProt Accessions	Q9R0N7	Gene names	Syt7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

SYTL3_MOUSE
θ value	1.58096e-12 (rank : 28)	NC score	0.484267 (rank : 19)
Query Neighborhood Hits	181	Target Neighborhood Hits	110	Shared Neighborhood Hits	73
SwissProt Accessions	Q99N48, Q8C506, Q99N47, Q99N49, Q99N54, Q99N79	Gene names	Sytl3, Slp3
Domain Architecture
Description	Synaptotagmin-like protein 3 (Exophilin-6).

PCLO_MOUSE
θ value	2.0648e-12 (rank : 29)	NC score	0.299274 (rank : 74)
Query Neighborhood Hits	181	Target Neighborhood Hits	2275	Shared Neighborhood Hits	117
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RP3A_HUMAN
θ value	1.74796e-11 (rank : 30)	NC score	0.432198 (rank : 32)
Query Neighborhood Hits	181	Target Neighborhood Hits	305	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

RIMS1_HUMAN
θ value	2.28291e-11 (rank : 31)	NC score	0.395278 (rank : 58)
Query Neighborhood Hits	181	Target Neighborhood Hits	437	Shared Neighborhood Hits	77
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

DOC2B_HUMAN
θ value	2.98157e-11 (rank : 32)	NC score	0.442054 (rank : 28)
Query Neighborhood Hits	181	Target Neighborhood Hits	150	Shared Neighborhood Hits	76
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

DOC2A_MOUSE
θ value	3.89403e-11 (rank : 33)	NC score	0.440270 (rank : 30)
Query Neighborhood Hits	181	Target Neighborhood Hits	140	Shared Neighborhood Hits	74
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

RP3A_MOUSE
θ value	3.89403e-11 (rank : 34)	NC score	0.426125 (rank : 35)
Query Neighborhood Hits	181	Target Neighborhood Hits	510	Shared Neighborhood Hits	88
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

DOC2A_HUMAN
θ value	6.64225e-11 (rank : 35)	NC score	0.440654 (rank : 29)
Query Neighborhood Hits	181	Target Neighborhood Hits	144	Shared Neighborhood Hits	75
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

DOC2B_MOUSE
θ value	8.67504e-11 (rank : 36)	NC score	0.439950 (rank : 31)
Query Neighborhood Hits	181	Target Neighborhood Hits	169	Shared Neighborhood Hits	76
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

SYT6_MOUSE
θ value	4.30538e-10 (rank : 37)	NC score	0.407839 (rank : 47)
Query Neighborhood Hits	181	Target Neighborhood Hits	132	Shared Neighborhood Hits	75
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

FA62A_HUMAN
θ value	5.62301e-10 (rank : 38)	NC score	0.413912 (rank : 37)
Query Neighborhood Hits	181	Target Neighborhood Hits	168	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

SYT6_HUMAN
θ value	1.63604e-09 (rank : 39)	NC score	0.405992 (rank : 48)
Query Neighborhood Hits	181	Target Neighborhood Hits	138	Shared Neighborhood Hits	75
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYTL2_MOUSE
θ value	1.63604e-09 (rank : 40)	NC score	0.450524 (rank : 27)
Query Neighborhood Hits	181	Target Neighborhood Hits	253	Shared Neighborhood Hits	79
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYTL2_HUMAN
θ value	2.13673e-09 (rank : 41)	NC score	0.453863 (rank : 26)
Query Neighborhood Hits	181	Target Neighborhood Hits	248	Shared Neighborhood Hits	76
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

FRAP_HUMAN
θ value	6.21693e-09 (rank : 42)	NC score	0.355569 (rank : 68)
Query Neighborhood Hits	181	Target Neighborhood Hits	83	Shared Neighborhood Hits	29
SwissProt Accessions	P42345, Q6LE87, Q96QG3, Q9Y4I3	Gene names	FRAP1, FRAP, FRAP2
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

FRAP_MOUSE
θ value	6.21693e-09 (rank : 43)	NC score	0.356567 (rank : 67)
Query Neighborhood Hits	181	Target Neighborhood Hits	77	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JLN9, Q811J5, Q9CST1	Gene names	Frap1, Frap
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

SYT1_HUMAN
θ value	1.80886e-08 (rank : 44)	NC score	0.407891 (rank : 45)
Query Neighborhood Hits	181	Target Neighborhood Hits	150	Shared Neighborhood Hits	76
SwissProt Accessions	P21579	Gene names	SYT1, SYT
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT1_MOUSE
θ value	1.80886e-08 (rank : 45)	NC score	0.407886 (rank : 46)
Query Neighborhood Hits	181	Target Neighborhood Hits	150	Shared Neighborhood Hits	76
SwissProt Accessions	P46096	Gene names	Syt1
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT5_HUMAN
θ value	2.36244e-08 (rank : 46)	NC score	0.411885 (rank : 42)
Query Neighborhood Hits	181	Target Neighborhood Hits	138	Shared Neighborhood Hits	76
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

DOC2G_MOUSE
θ value	3.08544e-08 (rank : 47)	NC score	0.424130 (rank : 36)
Query Neighborhood Hits	181	Target Neighborhood Hits	125	Shared Neighborhood Hits	71
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

RIMS4_HUMAN
θ value	5.26297e-08 (rank : 48)	NC score	0.392363 (rank : 62)
Query Neighborhood Hits	181	Target Neighborhood Hits	76	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H426, Q5JWT7	Gene names	RIMS4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

RIMS4_MOUSE
θ value	5.26297e-08 (rank : 49)	NC score	0.393731 (rank : 60)
Query Neighborhood Hits	181	Target Neighborhood Hits	76	Shared Neighborhood Hits	71
SwissProt Accessions	P60191	Gene names	Rims4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

RIMS2_MOUSE
θ value	6.87365e-08 (rank : 50)	NC score	0.376674 (rank : 65)
Query Neighborhood Hits	181	Target Neighborhood Hits	376	Shared Neighborhood Hits	75
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

SYT10_HUMAN
θ value	6.87365e-08 (rank : 51)	NC score	0.398379 (rank : 53)
Query Neighborhood Hits	181	Target Neighborhood Hits	134	Shared Neighborhood Hits	75
SwissProt Accessions	Q6XYQ8	Gene names	SYT10
Domain Architecture	No domain graphic available
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT10_MOUSE
θ value	6.87365e-08 (rank : 52)	NC score	0.398307 (rank : 54)
Query Neighborhood Hits	181	Target Neighborhood Hits	133	Shared Neighborhood Hits	76
SwissProt Accessions	Q9R0N4	Gene names	Syt10
Domain Architecture
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT12_HUMAN
θ value	6.87365e-08 (rank : 53)	NC score	0.413723 (rank : 38)
Query Neighborhood Hits	181	Target Neighborhood Hits	100	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IV01	Gene names	SYT12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT15_HUMAN
θ value	8.97725e-08 (rank : 54)	NC score	0.412225 (rank : 40)
Query Neighborhood Hits	181	Target Neighborhood Hits	112	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BQS2, Q7Z439, Q7Z440	Gene names	SYT15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV) (Chr10Syt).

SYT2_MOUSE
θ value	1.17247e-07 (rank : 55)	NC score	0.410418 (rank : 43)
Query Neighborhood Hits	181	Target Neighborhood Hits	143	Shared Neighborhood Hits	76
SwissProt Accessions	P46097, Q8R0E1	Gene names	Syt2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT3_HUMAN
θ value	1.17247e-07 (rank : 56)	NC score	0.404797 (rank : 49)
Query Neighborhood Hits	181	Target Neighborhood Hits	145	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BQG1, Q8N5Z1, Q8N640	Gene names	SYT3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

RIMS2_HUMAN
θ value	1.53129e-07 (rank : 57)	NC score	0.380288 (rank : 64)
Query Neighborhood Hits	181	Target Neighborhood Hits	342	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

SYT12_MOUSE
θ value	1.53129e-07 (rank : 58)	NC score	0.411955 (rank : 41)
Query Neighborhood Hits	181	Target Neighborhood Hits	102	Shared Neighborhood Hits	69
SwissProt Accessions	Q920N7	Gene names	Syt12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT2_HUMAN
θ value	1.53129e-07 (rank : 59)	NC score	0.410294 (rank : 44)
Query Neighborhood Hits	181	Target Neighborhood Hits	142	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N9I0, Q496K5, Q8NBE5	Gene names	SYT2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT7_HUMAN
θ value	1.53129e-07 (rank : 60)	NC score	0.413489 (rank : 39)
Query Neighborhood Hits	181	Target Neighborhood Hits	137	Shared Neighborhood Hits	75
SwissProt Accessions	O43581	Gene names	SYT7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

SYT3_MOUSE
θ value	3.41135e-07 (rank : 61)	NC score	0.403354 (rank : 50)
Query Neighborhood Hits	181	Target Neighborhood Hits	147	Shared Neighborhood Hits	75
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

KPCA_HUMAN
θ value	4.45536e-07 (rank : 62)	NC score	0.110445 (rank : 117)
Query Neighborhood Hits	181	Target Neighborhood Hits	1070	Shared Neighborhood Hits	78
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCB_HUMAN
θ value	2.21117e-06 (rank : 63)	NC score	0.106207 (rank : 120)
Query Neighborhood Hits	181	Target Neighborhood Hits	1121	Shared Neighborhood Hits	78
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

SYT5_MOUSE
θ value	2.88788e-06 (rank : 64)	NC score	0.403132 (rank : 51)
Query Neighborhood Hits	181	Target Neighborhood Hits	140	Shared Neighborhood Hits	76
SwissProt Accessions	Q9R0N5	Gene names	Syt5, Syt9
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin IX).

KPCA_MOUSE
θ value	4.92598e-06 (rank : 65)	NC score	0.107232 (rank : 119)
Query Neighborhood Hits	181	Target Neighborhood Hits	1067	Shared Neighborhood Hits	78
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

ATR_MOUSE
θ value	6.43352e-06 (rank : 66)	NC score	0.288746 (rank : 75)
Query Neighborhood Hits	181	Target Neighborhood Hits	63	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JKK8	Gene names	Atr
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein).

SYT4_HUMAN
θ value	6.43352e-06 (rank : 67)	NC score	0.398726 (rank : 52)
Query Neighborhood Hits	181	Target Neighborhood Hits	121	Shared Neighborhood Hits	74
SwissProt Accessions	Q9H2B2, Q9P2K4	Gene names	SYT4, KIAA1342
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

SYT4_MOUSE
θ value	6.43352e-06 (rank : 68)	NC score	0.396537 (rank : 55)
Query Neighborhood Hits	181	Target Neighborhood Hits	123	Shared Neighborhood Hits	74
SwissProt Accessions	P40749, Q3UFC1, Q8BGH3, Q8BRL6	Gene names	Syt4, Syt3
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

SYT9_MOUSE
θ value	6.43352e-06 (rank : 69)	NC score	0.392998 (rank : 61)
Query Neighborhood Hits	181	Target Neighborhood Hits	148	Shared Neighborhood Hits	76
SwissProt Accessions	Q9R0N9, Q8C280	Gene names	Syt9, Syt5
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V).

KPCB_MOUSE
θ value	8.40245e-06 (rank : 70)	NC score	0.105910 (rank : 121)
Query Neighborhood Hits	181	Target Neighborhood Hits	1117	Shared Neighborhood Hits	77
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

SYT9_HUMAN
θ value	8.40245e-06 (rank : 71)	NC score	0.394496 (rank : 59)
Query Neighborhood Hits	181	Target Neighborhood Hits	144	Shared Neighborhood Hits	76
SwissProt Accessions	Q86SS6	Gene names	SYT9
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX).

ATR_HUMAN
θ value	1.87187e-05 (rank : 72)	NC score	0.288660 (rank : 76)
Query Neighborhood Hits	181	Target Neighborhood Hits	71	Shared Neighborhood Hits	28
SwissProt Accessions	Q13535, Q7KYL3, Q93051, Q9BXK4	Gene names	ATR, FRP1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) (FRAP-related protein 1).

KPCG_MOUSE
θ value	1.87187e-05 (rank : 73)	NC score	0.115203 (rank : 114)
Query Neighborhood Hits	181	Target Neighborhood Hits	1123	Shared Neighborhood Hits	78
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCG_HUMAN
θ value	4.1701e-05 (rank : 74)	NC score	0.114024 (rank : 115)
Query Neighborhood Hits	181	Target Neighborhood Hits	1126	Shared Neighborhood Hits	78
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

NCF1_HUMAN
θ value	7.1131e-05 (rank : 75)	NC score	0.108895 (rank : 118)
Query Neighborhood Hits	181	Target Neighborhood Hits	198	Shared Neighborhood Hits	10
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

RGS3_HUMAN
θ value	0.000121331 (rank : 76)	NC score	0.151266 (rank : 98)
Query Neighborhood Hits	181	Target Neighborhood Hits	1375	Shared Neighborhood Hits	96
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SYT11_HUMAN
θ value	0.000121331 (rank : 77)	NC score	0.395769 (rank : 57)
Query Neighborhood Hits	181	Target Neighborhood Hits	113	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BT88, Q14998, Q68CT5, Q8IXU3, Q96SU2	Gene names	SYT11, KIAA0080
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT11_MOUSE
θ value	0.000121331 (rank : 78)	NC score	0.396382 (rank : 56)
Query Neighborhood Hits	181	Target Neighborhood Hits	116	Shared Neighborhood Hits	75
SwissProt Accessions	Q9R0N3	Gene names	Syt11
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT15_MOUSE
θ value	0.000158464 (rank : 79)	NC score	0.382326 (rank : 63)
Query Neighborhood Hits	181	Target Neighborhood Hits	100	Shared Neighborhood Hits	74
SwissProt Accessions	Q8C6N3, Q7TN81, Q7TN82, Q8C999	Gene names	Syt15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV).

RASA3_HUMAN
θ value	0.00035302 (rank : 80)	NC score	0.193773 (rank : 87)
Query Neighborhood Hits	181	Target Neighborhood Hits	166	Shared Neighborhood Hits	69
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

PRKDC_HUMAN
θ value	0.000786445 (rank : 81)	NC score	0.299951 (rank : 73)
Query Neighborhood Hits	181	Target Neighborhood Hits	93	Shared Neighborhood Hits	28
SwissProt Accessions	P78527, P78528, Q13327, Q13337, Q14175, Q59H99, Q7Z611, Q96SE6, Q9UME3	Gene names	PRKDC
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (DNPK1) (p460).

NCF1_MOUSE
θ value	0.00134147 (rank : 82)	NC score	0.099993 (rank : 122)
Query Neighborhood Hits	181	Target Neighborhood Hits	198	Shared Neighborhood Hits	9
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

PRKDC_MOUSE
θ value	0.00134147 (rank : 83)	NC score	0.308168 (rank : 72)
Query Neighborhood Hits	181	Target Neighborhood Hits	92	Shared Neighborhood Hits	29
SwissProt Accessions	P97313, O88187, P97928, Q307W9, Q3V2W8, Q8C2A7, Q9Z341	Gene names	Prkdc, Xrcc7
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (P460).

SMG1_HUMAN
θ value	0.00509761 (rank : 84)	NC score	0.228376 (rank : 85)
Query Neighborhood Hits	181	Target Neighborhood Hits	231	Shared Neighborhood Hits	31
SwissProt Accessions	Q96Q15, O43305, Q13284, Q8NFX2, Q96QV0, Q96RW3	Gene names	SMG1, ATX, KIAA0421, LIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1) (hSMG-1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (61E3.4).

SMG1_MOUSE
θ value	0.00509761 (rank : 85)	NC score	0.230069 (rank : 84)
Query Neighborhood Hits	181	Target Neighborhood Hits	212	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BKX6, Q5DU42, Q6ZQC0, Q8BLU4, Q8BWJ5, Q8BXD3	Gene names	Smg1, Kiaa0421
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1).

SYT8_MOUSE
θ value	0.0148317 (rank : 86)	NC score	0.369752 (rank : 66)
Query Neighborhood Hits	181	Target Neighborhood Hits	94	Shared Neighborhood Hits	68
SwissProt Accessions	Q9R0N6, Q64366, Q8C6E7	Gene names	Syt8
Domain Architecture
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

SPT5H_HUMAN
θ value	0.0252991 (rank : 87)	NC score	0.052415 (rank : 153)
Query Neighborhood Hits	181	Target Neighborhood Hits	436	Shared Neighborhood Hits	26
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	0.0252991 (rank : 88)	NC score	0.051780 (rank : 156)
Query Neighborhood Hits	181	Target Neighborhood Hits	437	Shared Neighborhood Hits	25
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

SGK3_MOUSE
θ value	0.0330416 (rank : 89)	NC score	0.023300 (rank : 178)
Query Neighborhood Hits	181	Target Neighborhood Hits	882	Shared Neighborhood Hits	23
SwissProt Accessions	Q9ERE3, Q3UAY2	Gene names	Sgk3, Cisk, Sgkl
Domain Architecture
Description	Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid- regulated kinase-like) (Cytokine-independent survival kinase).

SNX16_HUMAN
θ value	0.0330416 (rank : 90)	NC score	0.089263 (rank : 125)
Query Neighborhood Hits	181	Target Neighborhood Hits	110	Shared Neighborhood Hits	20
SwissProt Accessions	P57768, Q8N4U3	Gene names	SNX16
Domain Architecture
Description	Sorting nexin-16.

ACY2_MOUSE
θ value	0.0431538 (rank : 91)	NC score	0.030391 (rank : 169)
Query Neighborhood Hits	181	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R3P0, Q9D876, Q9DCE2, Q9JIN8	Gene names	Aspa
Domain Architecture
Description	Aspartoacylase (EC 3.5.1.15) (Aminoacylase-2) (ACY-2).

SGK3_HUMAN
θ value	0.0431538 (rank : 92)	NC score	0.023176 (rank : 179)
Query Neighborhood Hits	181	Target Neighborhood Hits	877	Shared Neighborhood Hits	24
SwissProt Accessions	Q96BR1, Q9P1Q7, Q9UKG5	Gene names	SGK3, SGKL
Domain Architecture
Description	Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid- regulated kinase-like).

SNX16_MOUSE
θ value	0.125558 (rank : 93)	NC score	0.089877 (rank : 124)
Query Neighborhood Hits	181	Target Neighborhood Hits	82	Shared Neighborhood Hits	19
SwissProt Accessions	Q8C080	Gene names	Snx16
Domain Architecture	No domain graphic available
Description	Sorting nexin-16.

NCF4_HUMAN
θ value	0.163984 (rank : 94)	NC score	0.047560 (rank : 159)
Query Neighborhood Hits	181	Target Neighborhood Hits	161	Shared Neighborhood Hits	17
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

RASA2_MOUSE
θ value	0.365318 (rank : 95)	NC score	0.186492 (rank : 93)
Query Neighborhood Hits	181	Target Neighborhood Hits	159	Shared Neighborhood Hits	66
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

CCNK_MOUSE
θ value	0.47712 (rank : 96)	NC score	0.026666 (rank : 175)
Query Neighborhood Hits	181	Target Neighborhood Hits	350	Shared Neighborhood Hits	19
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

RIMS3_HUMAN
θ value	0.47712 (rank : 97)	NC score	0.313270 (rank : 70)
Query Neighborhood Hits	181	Target Neighborhood Hits	66	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UJD0, Q92511	Gene names	RIMS3, KIAA0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RIMS3_MOUSE
θ value	0.47712 (rank : 98)	NC score	0.308750 (rank : 71)
Query Neighborhood Hits	181	Target Neighborhood Hits	67	Shared Neighborhood Hits	65
SwissProt Accessions	Q80U57	Gene names	Rims3, Kiaa0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

MAP2_HUMAN
θ value	0.62314 (rank : 99)	NC score	0.020257 (rank : 182)
Query Neighborhood Hits	181	Target Neighborhood Hits	348	Shared Neighborhood Hits	14
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

NED4L_HUMAN
θ value	0.62314 (rank : 100)	NC score	0.145008 (rank : 99)
Query Neighborhood Hits	181	Target Neighborhood Hits	238	Shared Neighborhood Hits	72
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_MOUSE
θ value	0.62314 (rank : 101)	NC score	0.142542 (rank : 102)
Query Neighborhood Hits	181	Target Neighborhood Hits	231	Shared Neighborhood Hits	71
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

AKAP9_HUMAN
θ value	0.813845 (rank : 102)	NC score	0.003200 (rank : 217)
Query Neighborhood Hits	181	Target Neighborhood Hits	1710	Shared Neighborhood Hits	20
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

RERE_MOUSE
θ value	0.813845 (rank : 103)	NC score	0.022534 (rank : 180)
Query Neighborhood Hits	181	Target Neighborhood Hits	785	Shared Neighborhood Hits	25
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RPB1_HUMAN
θ value	0.813845 (rank : 104)	NC score	0.032512 (rank : 168)
Query Neighborhood Hits	181	Target Neighborhood Hits	362	Shared Neighborhood Hits	16
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	0.813845 (rank : 105)	NC score	0.032731 (rank : 167)
Query Neighborhood Hits	181	Target Neighborhood Hits	363	Shared Neighborhood Hits	16
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

TENS1_HUMAN
θ value	0.813845 (rank : 106)	NC score	0.020729 (rank : 181)
Query Neighborhood Hits	181	Target Neighborhood Hits	400	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

TULP4_MOUSE
θ value	0.813845 (rank : 107)	NC score	0.017193 (rank : 184)
Query Neighborhood Hits	181	Target Neighborhood Hits	247	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

UN13B_HUMAN
θ value	0.813845 (rank : 108)	NC score	0.143872 (rank : 101)
Query Neighborhood Hits	181	Target Neighborhood Hits	217	Shared Neighborhood Hits	61
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

ATM_HUMAN
θ value	1.06291 (rank : 109)	NC score	0.250589 (rank : 81)
Query Neighborhood Hits	181	Target Neighborhood Hits	78	Shared Neighborhood Hits	29
SwissProt Accessions	Q13315, O15429, Q12758, Q16551, Q93007, Q9NP02, Q9UCX7	Gene names	ATM
Domain Architecture
Description	Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T, mutated).

PO121_HUMAN
θ value	1.06291 (rank : 110)	NC score	0.039912 (rank : 164)
Query Neighborhood Hits	181	Target Neighborhood Hits	344	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PO121_MOUSE
θ value	1.06291 (rank : 111)	NC score	0.037634 (rank : 165)
Query Neighborhood Hits	181	Target Neighborhood Hits	345	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

BPAEA_HUMAN
θ value	1.38821 (rank : 112)	NC score	0.002453 (rank : 220)
Query Neighborhood Hits	181	Target Neighborhood Hits	1369	Shared Neighborhood Hits	14
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CI093_HUMAN
θ value	1.38821 (rank : 113)	NC score	0.002941 (rank : 218)
Query Neighborhood Hits	181	Target Neighborhood Hits	1088	Shared Neighborhood Hits	15
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

NEDD4_HUMAN
θ value	1.38821 (rank : 114)	NC score	0.133541 (rank : 107)
Query Neighborhood Hits	181	Target Neighborhood Hits	214	Shared Neighborhood Hits	69
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

RERE_HUMAN
θ value	1.38821 (rank : 115)	NC score	0.019650 (rank : 183)
Query Neighborhood Hits	181	Target Neighborhood Hits	779	Shared Neighborhood Hits	27
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

UN13B_MOUSE
θ value	1.38821 (rank : 116)	NC score	0.144691 (rank : 100)
Query Neighborhood Hits	181	Target Neighborhood Hits	210	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

K0562_HUMAN
θ value	1.81305 (rank : 117)	NC score	0.026947 (rank : 174)
Query Neighborhood Hits	181	Target Neighborhood Hits	146	Shared Neighborhood Hits	7
SwissProt Accessions	O60308, Q5JSQ3, Q5SR24, Q5SR25, Q6PKF5, Q86W32, Q86X14	Gene names	KIAA0562
Domain Architecture	No domain graphic available
Description	Protein KIAA0562.

NOXO1_MOUSE
θ value	1.81305 (rank : 118)	NC score	0.052140 (rank : 154)
Query Neighborhood Hits	181	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

RASA2_HUMAN
θ value	1.81305 (rank : 119)	NC score	0.182493 (rank : 95)
Query Neighborhood Hits	181	Target Neighborhood Hits	157	Shared Neighborhood Hits	68
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

SNX18_HUMAN
θ value	1.81305 (rank : 120)	NC score	0.045491 (rank : 160)
Query Neighborhood Hits	181	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SNX18_MOUSE
θ value	1.81305 (rank : 121)	NC score	0.042412 (rank : 161)
Query Neighborhood Hits	181	Target Neighborhood Hits	198	Shared Neighborhood Hits	14
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SNX24_HUMAN
θ value	1.81305 (rank : 122)	NC score	0.041775 (rank : 162)
Query Neighborhood Hits	181	Target Neighborhood Hits	42	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y343, Q6UY33	Gene names	SNX24
Domain Architecture
Description	Sorting nexin-24.

SNX25_HUMAN
θ value	1.81305 (rank : 123)	NC score	0.034073 (rank : 166)
Query Neighborhood Hits	181	Target Neighborhood Hits	77	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H3E2	Gene names	SNX25
Domain Architecture
Description	Sorting nexin-25.

DYSF_HUMAN
θ value	2.36792 (rank : 124)	NC score	0.159354 (rank : 96)
Query Neighborhood Hits	181	Target Neighborhood Hits	170	Shared Neighborhood Hits	74
SwissProt Accessions	O75923, O75696, Q9UEN7	Gene names	DYSF, FER1L1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

DYSF_MOUSE
θ value	2.36792 (rank : 125)	NC score	0.154165 (rank : 97)
Query Neighborhood Hits	181	Target Neighborhood Hits	162	Shared Neighborhood Hits	73
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

MAML2_HUMAN
θ value	2.36792 (rank : 126)	NC score	0.012415 (rank : 196)
Query Neighborhood Hits	181	Target Neighborhood Hits	360	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

MEF2B_HUMAN
θ value	2.36792 (rank : 127)	NC score	0.014742 (rank : 189)
Query Neighborhood Hits	181	Target Neighborhood Hits	150	Shared Neighborhood Hits	10
SwissProt Accessions	Q02080	Gene names	MEF2B, XMEF2
Domain Architecture
Description	Myocyte-specific enhancer factor 2B (Serum response factor-like protein 2) (XMEF2) (RSRFR2).

MUC2_HUMAN
θ value	2.36792 (rank : 128)	NC score	0.014103 (rank : 190)
Query Neighborhood Hits	181	Target Neighborhood Hits	906	Shared Neighborhood Hits	25
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

SMRC2_HUMAN
θ value	2.36792 (rank : 129)	NC score	0.015122 (rank : 186)
Query Neighborhood Hits	181	Target Neighborhood Hits	499	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SNX13_MOUSE
θ value	2.36792 (rank : 130)	NC score	0.025275 (rank : 176)
Query Neighborhood Hits	181	Target Neighborhood Hits	86	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PHS6	Gene names	Snx13
Domain Architecture	No domain graphic available
Description	Sorting nexin-13.

SNX24_MOUSE
θ value	2.36792 (rank : 131)	NC score	0.040872 (rank : 163)
Query Neighborhood Hits	181	Target Neighborhood Hits	40	Shared Neighborhood Hits	11
SwissProt Accessions	Q9CRB0	Gene names	Snx24
Domain Architecture	No domain graphic available
Description	Sorting nexin-24.

TFG_HUMAN
θ value	2.36792 (rank : 132)	NC score	0.054220 (rank : 150)
Query Neighborhood Hits	181	Target Neighborhood Hits	122	Shared Neighborhood Hits	13
SwissProt Accessions	Q92734, Q15656	Gene names	TFG
Domain Architecture
Description	Protein TFG (TRK-fused gene protein).

ATM_MOUSE
θ value	3.0926 (rank : 133)	NC score	0.241132 (rank : 83)
Query Neighborhood Hits	181	Target Neighborhood Hits	93	Shared Neighborhood Hits	28
SwissProt Accessions	Q62388	Gene names	Atm
Domain Architecture
Description	Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated homolog) (A-T, mutated homolog).

CPNE6_HUMAN
θ value	3.0926 (rank : 134)	NC score	0.056257 (rank : 149)
Query Neighborhood Hits	181	Target Neighborhood Hits	85	Shared Neighborhood Hits	47
SwissProt Accessions	O95741, Q53HA6, Q8WVG1	Gene names	CPNE6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

GPTC2_MOUSE
θ value	3.0926 (rank : 135)	NC score	0.012707 (rank : 193)
Query Neighborhood Hits	181	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TQC7, Q8BNJ9, Q8BPM1, Q8CDH9	Gene names	Gpatc2
Domain Architecture
Description	G patch domain-containing protein 2.

AUTS2_HUMAN
θ value	4.03905 (rank : 136)	NC score	0.029820 (rank : 170)
Query Neighborhood Hits	181	Target Neighborhood Hits	342	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

DDX58_MOUSE
θ value	4.03905 (rank : 137)	NC score	0.006215 (rank : 213)
Query Neighborhood Hits	181	Target Neighborhood Hits	99	Shared Neighborhood Hits	2
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

GLIS1_MOUSE
θ value	4.03905 (rank : 138)	NC score	-0.003922 (rank : 230)
Query Neighborhood Hits	181	Target Neighborhood Hits	751	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K1M4, Q6NZF6, Q8R4Z3	Gene names	Glis1, Gli5
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS1 (GLI-similar 1) (Gli homologous protein 1) (GliH1).

MYH11_HUMAN
θ value	4.03905 (rank : 139)	NC score	-0.002390 (rank : 229)
Query Neighborhood Hits	181	Target Neighborhood Hits	1806	Shared Neighborhood Hits	19
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

POGZ_HUMAN
θ value	4.03905 (rank : 140)	NC score	-0.001536 (rank : 228)
Query Neighborhood Hits	181	Target Neighborhood Hits	745	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z3K3, O75049, Q8TDZ7, Q9Y4X7	Gene names	POGZ, KIAA0461
Domain Architecture
Description	Pogo transposable element with ZNF domain.

PP2CD_HUMAN
θ value	4.03905 (rank : 141)	NC score	0.008372 (rank : 204)
Query Neighborhood Hits	181	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	O15297	Gene names	PPM1D, WIP1
Domain Architecture
Description	Protein phosphatase 2C isoform delta (EC 3.1.3.16) (PP2C-delta) (p53- induced protein phosphatase 1) (Protein phosphatase magnesium- dependent 1 delta).

SNX23_HUMAN
θ value	4.03905 (rank : 142)	NC score	0.002884 (rank : 219)
Query Neighborhood Hits	181	Target Neighborhood Hits	944	Shared Neighborhood Hits	26
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

TINF2_HUMAN
θ value	4.03905 (rank : 143)	NC score	0.012532 (rank : 194)
Query Neighborhood Hits	181	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BSI4, Q9H904, Q9UHC2	Gene names	TINF2, TIN2
Domain Architecture	No domain graphic available
Description	TERF1-interacting nuclear factor 2 (TRF1-interacting nuclear protein 2).

ZYX_HUMAN
θ value	4.03905 (rank : 144)	NC score	0.006681 (rank : 210)
Query Neighborhood Hits	181	Target Neighborhood Hits	387	Shared Neighborhood Hits	9
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

BPA1_MOUSE
θ value	5.27518 (rank : 145)	NC score	0.000602 (rank : 223)
Query Neighborhood Hits	181	Target Neighborhood Hits	1477	Shared Neighborhood Hits	15
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BRCA2_MOUSE
θ value	5.27518 (rank : 146)	NC score	0.010973 (rank : 197)
Query Neighborhood Hits	181	Target Neighborhood Hits	222	Shared Neighborhood Hits	14
SwissProt Accessions	P97929, O35922, P97383	Gene names	Brca2, Fancd1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein homolog (Fanconi anemia group D1 protein homolog).

EXOS7_HUMAN
θ value	5.27518 (rank : 147)	NC score	0.008697 (rank : 202)
Query Neighborhood Hits	181	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q15024, Q96E72	Gene names	EXOSC7, KIAA0116, RRP42
Domain Architecture
Description	Exosome complex exonuclease RRP42 (EC 3.1.13.-) (Ribosomal RNA- processing protein 42) (Exosome component 7) (p8).

K1802_HUMAN
θ value	5.27518 (rank : 148)	NC score	0.007682 (rank : 205)
Query Neighborhood Hits	181	Target Neighborhood Hits	1378	Shared Neighborhood Hits	32
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MYO15_MOUSE
θ value	5.27518 (rank : 149)	NC score	0.007671 (rank : 206)
Query Neighborhood Hits	181	Target Neighborhood Hits	467	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PRRT3_HUMAN
θ value	5.27518 (rank : 150)	NC score	0.023503 (rank : 177)
Query Neighborhood Hits	181	Target Neighborhood Hits	998	Shared Neighborhood Hits	33
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

STIM2_MOUSE
θ value	5.27518 (rank : 151)	NC score	0.009417 (rank : 200)
Query Neighborhood Hits	181	Target Neighborhood Hits	403	Shared Neighborhood Hits	8
SwissProt Accessions	P83093, Q69ZI3, Q80VF4	Gene names	Stim2, Kiaa1482
Domain Architecture	No domain graphic available
Description	Stromal interaction molecule 2 precursor.

SYNJ1_HUMAN
θ value	5.27518 (rank : 152)	NC score	0.010311 (rank : 199)
Query Neighborhood Hits	181	Target Neighborhood Hits	498	Shared Neighborhood Hits	16
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TIMD4_MOUSE
θ value	5.27518 (rank : 153)	NC score	0.008414 (rank : 203)
Query Neighborhood Hits	181	Target Neighborhood Hits	65	Shared Neighborhood Hits	2
SwissProt Accessions	Q6U7R4, Q6U7R3, Q8CIC7	Gene names	Timd4, Tim4
Domain Architecture	No domain graphic available
Description	T-cell immunoglobulin and mucin domain-containing protein 4 precursor (TIMD-4) (T-cell membrane protein 4) (TIM-4) (Spleen, mucin- containing, knockout of lymphotoxin protein) (SMUCKLER).

TP53B_HUMAN
θ value	5.27518 (rank : 154)	NC score	0.029455 (rank : 172)
Query Neighborhood Hits	181	Target Neighborhood Hits	413	Shared Neighborhood Hits	16
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

ATBF1_MOUSE
θ value	6.88961 (rank : 155)	NC score	-0.001261 (rank : 226)
Query Neighborhood Hits	181	Target Neighborhood Hits	1841	Shared Neighborhood Hits	33
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

BSN_MOUSE
θ value	6.88961 (rank : 156)	NC score	0.049889 (rank : 158)
Query Neighborhood Hits	181	Target Neighborhood Hits	2057	Shared Neighborhood Hits	47
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CCD95_HUMAN
θ value	6.88961 (rank : 157)	NC score	0.014975 (rank : 188)
Query Neighborhood Hits	181	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NBZ0	Gene names	CCDC95
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 95.

DPYD_HUMAN
θ value	6.88961 (rank : 158)	NC score	0.016965 (rank : 185)
Query Neighborhood Hits	181	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q12882, Q16694, Q16761, Q96TH1	Gene names	DPYD
Domain Architecture
Description	Dihydropyrimidine dehydrogenase [NADP+] precursor (EC 1.3.1.2) (DPD) (DHPDHase) (Dihydrouracil dehydrogenase) (Dihydrothymine dehydrogenase).

HS105_HUMAN
θ value	6.88961 (rank : 159)	NC score	0.005470 (rank : 215)
Query Neighborhood Hits	181	Target Neighborhood Hits	209	Shared Neighborhood Hits	12
SwissProt Accessions	Q92598, O95739, Q5TBM6, Q5TBM8, Q9UPC4	Gene names	HSPH1, HSP105, HSP110, KIAA0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock 110 kDa protein) (Antigen NY- CO-25).

HXA11_HUMAN
θ value	6.88961 (rank : 160)	NC score	0.001245 (rank : 222)
Query Neighborhood Hits	181	Target Neighborhood Hits	334	Shared Neighborhood Hits	7
SwissProt Accessions	P31270	Gene names	HOXA11, HOX1I
Domain Architecture
Description	Homeobox protein Hox-A11 (Hox-1I).

HXA11_MOUSE
θ value	6.88961 (rank : 161)	NC score	0.001270 (rank : 221)
Query Neighborhood Hits	181	Target Neighborhood Hits	327	Shared Neighborhood Hits	7
SwissProt Accessions	P31311, Q3V026	Gene names	Hoxa11, Hox-1.9, Hoxa-11
Domain Architecture
Description	Homeobox protein Hox-A11 (Hox-1.9).

INP4B_HUMAN
θ value	6.88961 (rank : 162)	NC score	0.006600 (rank : 212)
Query Neighborhood Hits	181	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	O15327, Q6IN59, Q6PJB4	Gene names	INPP4B
Domain Architecture	No domain graphic available
Description	Type II inositol-3,4-bisphosphate 4-phosphatase (EC 3.1.3.66) (Inositol polyphosphate 4-phosphatase type II).

MELPH_MOUSE
θ value	6.88961 (rank : 163)	NC score	0.078271 (rank : 133)
Query Neighborhood Hits	181	Target Neighborhood Hits	112	Shared Neighborhood Hits	14
SwissProt Accessions	Q91V27, Q99N53	Gene names	Mlph, Ln, Slac2a
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Leaden protein) (Synaptotagmin-like protein 2a) (Slac2-a) (Slp homolog lacking C2 domains a).

MUC5B_HUMAN
θ value	6.88961 (rank : 164)	NC score	0.005438 (rank : 216)
Query Neighborhood Hits	181	Target Neighborhood Hits	1020	Shared Neighborhood Hits	15
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NEDD4_MOUSE
θ value	6.88961 (rank : 165)	NC score	0.122855 (rank : 111)
Query Neighborhood Hits	181	Target Neighborhood Hits	212	Shared Neighborhood Hits	68
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

NFIA_HUMAN
θ value	6.88961 (rank : 166)	NC score	0.007299 (rank : 207)
Query Neighborhood Hits	181	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	Q12857, Q9H3X9, Q9P2A9	Gene names	NFIA, KIAA1439
Domain Architecture
Description	Nuclear factor 1 A-type (Nuclear factor 1/A) (NF1-A) (NFI-A) (NF-I/A) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

NFIA_MOUSE
θ value	6.88961 (rank : 167)	NC score	0.007269 (rank : 208)
Query Neighborhood Hits	181	Target Neighborhood Hits	69	Shared Neighborhood Hits	5
SwissProt Accessions	Q02780, P70250, P70251, Q3UUZ2, Q61960, Q8VBT5, Q9R1G5	Gene names	Nfia
Domain Architecture
Description	Nuclear factor 1 A-type (Nuclear factor 1/A) (NF1-A) (NFI-A) (NF-I/A) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

SMRC2_MOUSE
θ value	6.88961 (rank : 168)	NC score	0.013674 (rank : 191)
Query Neighborhood Hits	181	Target Neighborhood Hits	487	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SNX14_HUMAN
θ value	6.88961 (rank : 169)	NC score	0.029594 (rank : 171)
Query Neighborhood Hits	181	Target Neighborhood Hits	77	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y5W7, Q9BSD1	Gene names	SNX14
Domain Architecture
Description	Sorting nexin-14.

ADA30_HUMAN
θ value	8.99809 (rank : 170)	NC score	-0.000392 (rank : 225)
Query Neighborhood Hits	181	Target Neighborhood Hits	391	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

AP3B1_HUMAN
θ value	8.99809 (rank : 171)	NC score	0.012427 (rank : 195)
Query Neighborhood Hits	181	Target Neighborhood Hits	283	Shared Neighborhood Hits	7
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

EEA1_HUMAN
θ value	8.99809 (rank : 172)	NC score	-0.001272 (rank : 227)
Query Neighborhood Hits	181	Target Neighborhood Hits	1796	Shared Neighborhood Hits	23
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

ENH2_HUMAN
θ value	8.99809 (rank : 173)	NC score	0.005762 (rank : 214)
Query Neighborhood Hits	181	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	Q9N2J9	Gene names
Domain Architecture
Description	HERV-H_3q26 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p60) (HERV-H/env60) [Contains: Surface protein (SU); Transmembrane protein (TM)].

GPTC2_HUMAN
θ value	8.99809 (rank : 174)	NC score	0.008942 (rank : 201)
Query Neighborhood Hits	181	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NW75, Q86YE7	Gene names	GPATC2
Domain Architecture
Description	G patch domain-containing protein 2.

GUAD_MOUSE
θ value	8.99809 (rank : 175)	NC score	0.010793 (rank : 198)
Query Neighborhood Hits	181	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R111	Gene names	Gda
Domain Architecture
Description	Guanine deaminase (EC 3.5.4.3) (Guanase) (Guanine aminase) (Guanine aminohydrolase) (GAH).

MYCB2_MOUSE
θ value	8.99809 (rank : 176)	NC score	0.007229 (rank : 209)
Query Neighborhood Hits	181	Target Neighborhood Hits	307	Shared Neighborhood Hits	14
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

PRDM2_HUMAN
θ value	8.99809 (rank : 177)	NC score	-0.000078 (rank : 224)
Query Neighborhood Hits	181	Target Neighborhood Hits	1135	Shared Neighborhood Hits	21
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

SNX14_MOUSE
θ value	8.99809 (rank : 178)	NC score	0.028975 (rank : 173)
Query Neighborhood Hits	181	Target Neighborhood Hits	75	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BHY8	Gene names	Snx14
Domain Architecture	No domain graphic available
Description	Sorting nexin-14.

TBP_HUMAN
θ value	8.99809 (rank : 179)	NC score	0.012873 (rank : 192)
Query Neighborhood Hits	181	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	P20226, Q16845, Q9UC02	Gene names	TBP, TF2D, TFIID
Domain Architecture
Description	TATA-box-binding protein (TATA-box factor) (TATA-binding factor) (TATA sequence-binding protein) (Transcription initiation factor TFIID TBP subunit).

TULP4_HUMAN
θ value	8.99809 (rank : 180)	NC score	0.015044 (rank : 187)
Query Neighborhood Hits	181	Target Neighborhood Hits	426	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

ZC3H6_HUMAN
θ value	8.99809 (rank : 181)	NC score	0.006669 (rank : 211)
Query Neighborhood Hits	181	Target Neighborhood Hits	228	Shared Neighborhood Hits	8
SwissProt Accessions	P61129	Gene names	ZC3H6, KIAA2035, ZC3HDC6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

BAIP3_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.191584 (rank : 90)
Query Neighborhood Hits	181	Target Neighborhood Hits	108	Shared Neighborhood Hits	63
SwissProt Accessions	O94812, O94839, Q2M226, Q658J2, Q76N05, Q96RZ3, Q9UJK1	Gene names	BAIAP3, KIAA0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

BAIP3_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.189491 (rank : 92)
Query Neighborhood Hits	181	Target Neighborhood Hits	112	Shared Neighborhood Hits	61
SwissProt Accessions	Q80TT2, Q6RUT4	Gene names	Baiap3, Gm937, Kiaa0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

CPNE1_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.059674 (rank : 147)
Query Neighborhood Hits	181	Target Neighborhood Hits	70	Shared Neighborhood Hits	45
SwissProt Accessions	Q99829, Q6IBL3, Q9H243, Q9NTZ7	Gene names	CPNE1, CPN1
Domain Architecture
Description	Copine-1 (Copine I).

CPNE1_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.071782 (rank : 139)
Query Neighborhood Hits	181	Target Neighborhood Hits	83	Shared Neighborhood Hits	48
SwissProt Accessions	Q8C166, Q925K4, Q925K5	Gene names	Cpne1
Domain Architecture
Description	Copine-1 (Copine I).

CPNE2_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.071255 (rank : 141)
Query Neighborhood Hits	181	Target Neighborhood Hits	75	Shared Neighborhood Hits	44
SwissProt Accessions	Q96FN4, Q68D19, Q86XP9	Gene names	CPNE2
Domain Architecture
Description	Copine-2 (Copine II).

CPNE2_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.071389 (rank : 140)
Query Neighborhood Hits	181	Target Neighborhood Hits	82	Shared Neighborhood Hits	47
SwissProt Accessions	P59108, Q8K1D7	Gene names	Cpne2
Domain Architecture
Description	Copine-2 (Copine II).

CPNE3_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.082230 (rank : 128)
Query Neighborhood Hits	181	Target Neighborhood Hits	90	Shared Neighborhood Hits	45
SwissProt Accessions	O75131, Q8IYA1	Gene names	CPNE3, CPN3, KIAA0636
Domain Architecture
Description	Copine-3 (Copine III).

CPNE3_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.081623 (rank : 129)
Query Neighborhood Hits	181	Target Neighborhood Hits	90	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BT60, Q5CZX9, Q5DU22	Gene names	Cpne3, Kiaa0636
Domain Architecture
Description	Copine-3 (Copine III).

CPNE5_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.074732 (rank : 137)
Query Neighborhood Hits	181	Target Neighborhood Hits	88	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HCH3	Gene names	CPNE5, KIAA1599
Domain Architecture
Description	Copine-5 (Copine V).

CPNE5_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.074845 (rank : 136)
Query Neighborhood Hits	181	Target Neighborhood Hits	86	Shared Neighborhood Hits	47
SwissProt Accessions	Q8JZW4	Gene names	Cpne5
Domain Architecture
Description	Copine-5 (Copine V).

CPNE6_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.051992 (rank : 155)
Query Neighborhood Hits	181	Target Neighborhood Hits	87	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Z140	Gene names	Cpne6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

CPNE7_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.066872 (rank : 145)
Query Neighborhood Hits	181	Target Neighborhood Hits	92	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UBL6	Gene names	CPNE7
Domain Architecture
Description	Copine-7 (Copine VII).

CPNE8_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.070296 (rank : 142)
Query Neighborhood Hits	181	Target Neighborhood Hits	86	Shared Neighborhood Hits	48
SwissProt Accessions	Q86YQ8, Q2TB41	Gene names	CPNE8
Domain Architecture
Description	Copine-8 (Copine VIII).

CPNE8_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.068707 (rank : 143)
Query Neighborhood Hits	181	Target Neighborhood Hits	85	Shared Neighborhood Hits	48
SwissProt Accessions	Q9DC53, Q9CUZ8	Gene names	Cpne8
Domain Architecture
Description	Copine-8 (Copine VIII).

ITSN2_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.067425 (rank : 144)
Query Neighborhood Hits	181	Target Neighborhood Hits	1173	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ITSN2_MOUSE
θ value	θ > 10 (rank : 197)	NC score	0.060442 (rank : 146)
Query Neighborhood Hits	181	Target Neighborhood Hits	1371	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

K0528_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.192350 (rank : 88)
Query Neighborhood Hits	181	Target Neighborhood Hits	96	Shared Neighborhood Hits	59
SwissProt Accessions	Q86YS7, O60280, Q7Z619, Q86SU3	Gene names	KIAA0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

K0528_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.192255 (rank : 89)
Query Neighborhood Hits	181	Target Neighborhood Hits	102	Shared Neighborhood Hits	59
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

MELPH_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.075291 (rank : 135)
Query Neighborhood Hits	181	Target Neighborhood Hits	145	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BV36, Q9HA71	Gene names	MLPH, SLAC2A
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Synaptotagmin-like protein 2a) (Slp homolog lacking C2 domains a).

MYOF_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.138684 (rank : 103)
Query Neighborhood Hits	181	Target Neighborhood Hits	147	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NZM1, Q9HBU3, Q9NZM0, Q9ULL3, Q9Y4U4	Gene names	FER1L3, KIAA1207, MYOF
Domain Architecture
Description	Myoferlin (Fer-1-like protein 3).

MYRIP_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.079493 (rank : 131)
Query Neighborhood Hits	181	Target Neighborhood Hits	269	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

MYRIP_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.082403 (rank : 127)
Query Neighborhood Hits	181	Target Neighborhood Hits	207	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

OTOF_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.117026 (rank : 112)
Query Neighborhood Hits	181	Target Neighborhood Hits	168	Shared Neighborhood Hits	57
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

OTOF_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.115365 (rank : 113)
Query Neighborhood Hits	181	Target Neighborhood Hits	196	Shared Neighborhood Hits	58
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

PA24A_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.076292 (rank : 134)
Query Neighborhood Hits	181	Target Neighborhood Hits	88	Shared Neighborhood Hits	57
SwissProt Accessions	P47712	Gene names	PLA2G4A, CPLA2, PLA2G4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

PA24A_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.080411 (rank : 130)
Query Neighborhood Hits	181	Target Neighborhood Hits	100	Shared Neighborhood Hits	56
SwissProt Accessions	P47713	Gene names	Pla2g4a, Cpla2, Pla2g4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

PA24B_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.073482 (rank : 138)
Query Neighborhood Hits	181	Target Neighborhood Hits	89	Shared Neighborhood Hits	47
SwissProt Accessions	O95712, Q59GF9, Q8TB10, Q9UKV7	Gene names	PLA2G4B
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

PA24B_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.093936 (rank : 123)
Query Neighborhood Hits	181	Target Neighborhood Hits	102	Shared Neighborhood Hits	52
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

PA24D_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.111659 (rank : 116)
Query Neighborhood Hits	181	Target Neighborhood Hits	97	Shared Neighborhood Hits	57
SwissProt Accessions	Q86XP0, Q8N176	Gene names	PLA2G4D
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

PA24D_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.130200 (rank : 108)
Query Neighborhood Hits	181	Target Neighborhood Hits	100	Shared Neighborhood Hits	60
SwissProt Accessions	Q50L43, Q3TJC5	Gene names	Pla2g4d
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

PA24E_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.079315 (rank : 132)
Query Neighborhood Hits	181	Target Neighborhood Hits	89	Shared Neighborhood Hits	53
SwissProt Accessions	Q3MJ16, Q6ZSC0	Gene names	PLA2G4E
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

PA24E_MOUSE
θ value	θ > 10 (rank : 213)	NC score	0.088863 (rank : 126)
Query Neighborhood Hits	181	Target Neighborhood Hits	95	Shared Neighborhood Hits	55
SwissProt Accessions	Q50L42, Q8BX44	Gene names	Pla2g4e
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

PA24F_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.058477 (rank : 148)
Query Neighborhood Hits	181	Target Neighborhood Hits	93	Shared Neighborhood Hits	48
SwissProt Accessions	Q50L41, Q80VQ8, Q80VV9	Gene names	Pla2g4f
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

PLCD1_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.054199 (rank : 151)
Query Neighborhood Hits	181	Target Neighborhood Hits	93	Shared Neighborhood Hits	40
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

RASA3_MOUSE
θ value	θ > 10 (rank : 216)	NC score	0.129704 (rank : 109)
Query Neighborhood Hits	181	Target Neighborhood Hits	144	Shared Neighborhood Hits	63
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

RASL1_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.190052 (rank : 91)
Query Neighborhood Hits	181	Target Neighborhood Hits	142	Shared Neighborhood Hits	62
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

RASL1_MOUSE
θ value	θ > 10 (rank : 218)	NC score	0.183488 (rank : 94)
Query Neighborhood Hits	181	Target Neighborhood Hits	148	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

RASL2_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.248073 (rank : 82)
Query Neighborhood Hits	181	Target Neighborhood Hits	161	Shared Neighborhood Hits	70
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

RFIP1_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.053725 (rank : 152)
Query Neighborhood Hits	181	Target Neighborhood Hits	152	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

RFIP2_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.125657 (rank : 110)
Query Neighborhood Hits	181	Target Neighborhood Hits	97	Shared Neighborhood Hits	53
SwissProt Accessions	Q7L804, Q9Y2F0	Gene names	RAB11FIP2, KIAA0941
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11).

SYT13_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.277556 (rank : 78)
Query Neighborhood Hits	181	Target Neighborhood Hits	76	Shared Neighborhood Hits	57
SwissProt Accessions	Q7L8C5, Q9BQS3, Q9H041, Q9P2C0	Gene names	SYT13, KIAA1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

SYT13_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.282195 (rank : 77)
Query Neighborhood Hits	181	Target Neighborhood Hits	69	Shared Neighborhood Hits	59
SwissProt Accessions	Q9EQT6, Q6ZPR2, Q8BRK6	Gene names	Syt13, Kiaa1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

SYT14_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.271263 (rank : 79)
Query Neighborhood Hits	181	Target Neighborhood Hits	81	Shared Neighborhood Hits	53
SwissProt Accessions	Q8NB59, Q5THX7, Q707N3, Q707N4, Q707N5, Q707N6, Q707N7	Gene names	SYT14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

SYT14_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.270836 (rank : 80)
Query Neighborhood Hits	181	Target Neighborhood Hits	82	Shared Neighborhood Hits	55
SwissProt Accessions	Q7TN84	Gene names	Syt14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

TAC2N_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.137262 (rank : 104)
Query Neighborhood Hits	181	Target Neighborhood Hits	47	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N9U0	Gene names	MTAC2D1, C14orf47
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

TAC2N_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.136994 (rank : 105)
Query Neighborhood Hits	181	Target Neighborhood Hits	43	Shared Neighborhood Hits	34
SwissProt Accessions	Q91XT6, Q9D4A0	Gene names	Mtac2d1
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

UN13A_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.134477 (rank : 106)
Query Neighborhood Hits	181	Target Neighborhood Hits	285	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

UN13D_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.201809 (rank : 86)
Query Neighborhood Hits	181	Target Neighborhood Hits	117	Shared Neighborhood Hits	63
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

WWC1_MOUSE
θ value	θ > 10 (rank : 230)	NC score	0.050512 (rank : 157)
Query Neighborhood Hits	181	Target Neighborhood Hits	290	Shared Neighborhood Hits	31
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

Hits sorted by NC score

P3C2A_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	181	Target Neighborhood Hits	181	Shared Neighborhood Hits	181
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

P3C2A_HUMAN
NC score	0.995555 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	181	Target Neighborhood Hits	188	Shared Neighborhood Hits	138
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

P3C2B_HUMAN
NC score	0.980410 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	181	Target Neighborhood Hits	148	Shared Neighborhood Hits	111
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

P3C2G_MOUSE
NC score	0.916833 (rank : 4)	θ value	0 (rank : 5)
Query Neighborhood Hits	181	Target Neighborhood Hits	113	Shared Neighborhood Hits	87
SwissProt Accessions	O70167, O70168	Gene names	Pik3c2g
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

P3C2G_HUMAN
NC score	0.906437 (rank : 5)	θ value	0 (rank : 4)
Query Neighborhood Hits	181	Target Neighborhood Hits	92	Shared Neighborhood Hits	70
SwissProt Accessions	O75747	Gene names	PIK3C2G
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

PK3CG_HUMAN
NC score	0.837909 (rank : 6)	θ value	3.42535e-108 (rank : 7)
Query Neighborhood Hits	181	Target Neighborhood Hits	41	Shared Neighborhood Hits	28
SwissProt Accessions	P48736, Q8IV23, Q9BZC8	Gene names	PIK3CG
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PK3CG_MOUSE
NC score	0.837133 (rank : 7)	θ value	6.90186e-109 (rank : 6)
Query Neighborhood Hits	181	Target Neighborhood Hits	43	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JHG7	Gene names	Pik3cg, Pi3kg1
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PK3CA_MOUSE
NC score	0.835124 (rank : 8)	θ value	6.45994e-107 (rank : 9)
Query Neighborhood Hits	181	Target Neighborhood Hits	48	Shared Neighborhood Hits	28
SwissProt Accessions	P42337	Gene names	Pik3ca
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

PK3CA_HUMAN
NC score	0.835068 (rank : 9)	θ value	3.78717e-107 (rank : 8)
Query Neighborhood Hits	181	Target Neighborhood Hits	45	Shared Neighborhood Hits	28
SwissProt Accessions	P42336, Q99762	Gene names	PIK3CA
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

PK3CD_HUMAN
NC score	0.825653 (rank : 10)	θ value	2.15548e-94 (rank : 12)
Query Neighborhood Hits	181	Target Neighborhood Hits	40	Shared Neighborhood Hits	28
SwissProt Accessions	O00329, O15445	Gene names	PIK3CD
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

PK3CD_MOUSE
NC score	0.825167 (rank : 11)	θ value	2.38316e-93 (rank : 13)
Query Neighborhood Hits	181	Target Neighborhood Hits	42	Shared Neighborhood Hits	28
SwissProt Accessions	O35904	Gene names	Pik3cd
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

PK3CB_MOUSE
NC score	0.822820 (rank : 12)	θ value	1.26366e-94 (rank : 10)
Query Neighborhood Hits	181	Target Neighborhood Hits	49	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BTI9	Gene names	Pik3cb
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

PK3CB_HUMAN
NC score	0.822657 (rank : 13)	θ value	2.15548e-94 (rank : 11)
Query Neighborhood Hits	181	Target Neighborhood Hits	43	Shared Neighborhood Hits	28
SwissProt Accessions	P42338	Gene names	PIK3CB
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

PK3C3_HUMAN
NC score	0.763152 (rank : 14)	θ value	1.73182e-43 (rank : 14)
Query Neighborhood Hits	181	Target Neighborhood Hits	49	Shared Neighborhood Hits	28
SwissProt Accessions	Q8NEB9, Q15134	Gene names	PIK3C3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3) (Phosphatidylinositol 3-kinase p100 subunit).

PK3C3_MOUSE
NC score	0.762026 (rank : 15)	θ value	2.95404e-43 (rank : 15)
Query Neighborhood Hits	181	Target Neighborhood Hits	49	Shared Neighborhood Hits	28
SwissProt Accessions	Q6PF93, Q8R3S8	Gene names	Pik3c3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3).

PI4KA_HUMAN
NC score	0.732404 (rank : 16)	θ value	3.06405e-32 (rank : 16)
Query Neighborhood Hits	181	Target Neighborhood Hits	53	Shared Neighborhood Hits	28
SwissProt Accessions	P42356, Q7Z625, Q9UPG2	Gene names	PIK4CA, PIK4
Domain Architecture
Description	Phosphatidylinositol 4-kinase alpha (EC 2.7.1.67) (PI4-kinase alpha) (PtdIns-4-kinase alpha) (PI4K-alpha).

PI4KB_MOUSE
NC score	0.686058 (rank : 17)	θ value	7.56453e-23 (rank : 18)
Query Neighborhood Hits	181	Target Neighborhood Hits	67	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BKC8, Q8C146	Gene names	Pik4cb
Domain Architecture
Description	Phosphatidylinositol 4-kinase beta (EC 2.7.1.67) (PtdIns 4-kinase beta) (PI4Kbeta) (PI4K-beta).

PI4KB_HUMAN
NC score	0.685129 (rank : 18)	θ value	4.43474e-23 (rank : 17)
Query Neighborhood Hits	181	Target Neighborhood Hits	79	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UBF8, O15096, P78405, Q9BWR6	Gene names	PIK4CB, PI4KB
Domain Architecture
Description	Phosphatidylinositol 4-kinase beta (EC 2.7.1.67) (PtdIns 4-kinase beta) (PI4Kbeta) (PI4K-beta) (NPIK) (PI4K92).

SYTL3_MOUSE
NC score	0.484267 (rank : 19)	θ value	1.58096e-12 (rank : 28)
Query Neighborhood Hits	181	Target Neighborhood Hits	110	Shared Neighborhood Hits	73
SwissProt Accessions	Q99N48, Q8C506, Q99N47, Q99N49, Q99N54, Q99N79	Gene names	Sytl3, Slp3
Domain Architecture
Description	Synaptotagmin-like protein 3 (Exophilin-6).

SYTL1_HUMAN
NC score	0.472706 (rank : 20)	θ value	3.18553e-13 (rank : 25)
Query Neighborhood Hits	181	Target Neighborhood Hits	227	Shared Neighborhood Hits	82
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

SYTL4_HUMAN
NC score	0.472449 (rank : 21)	θ value	3.76295e-14 (rank : 21)
Query Neighborhood Hits	181	Target Neighborhood Hits	138	Shared Neighborhood Hits	74
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL4_MOUSE
NC score	0.470263 (rank : 22)	θ value	1.42992e-13 (rank : 23)
Query Neighborhood Hits	181	Target Neighborhood Hits	137	Shared Neighborhood Hits	75
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL5_MOUSE
NC score	0.469542 (rank : 23)	θ value	5.43371e-13 (rank : 26)
Query Neighborhood Hits	181	Target Neighborhood Hits	154	Shared Neighborhood Hits	76
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SYTL5_HUMAN
NC score	0.469191 (rank : 24)	θ value	2.20605e-14 (rank : 19)
Query Neighborhood Hits	181	Target Neighborhood Hits	237	Shared Neighborhood Hits	78
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SYTL1_MOUSE
NC score	0.457092 (rank : 25)	θ value	4.91457e-14 (rank : 22)
Query Neighborhood Hits	181	Target Neighborhood Hits	314	Shared Neighborhood Hits	76
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

SYTL2_HUMAN
NC score	0.453863 (rank : 26)	θ value	2.13673e-09 (rank : 41)
Query Neighborhood Hits	181	Target Neighborhood Hits	248	Shared Neighborhood Hits	76
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYTL2_MOUSE
NC score	0.450524 (rank : 27)	θ value	1.63604e-09 (rank : 40)
Query Neighborhood Hits	181	Target Neighborhood Hits	253	Shared Neighborhood Hits	79
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

DOC2B_HUMAN
NC score	0.442054 (rank : 28)	θ value	2.98157e-11 (rank : 32)
Query Neighborhood Hits	181	Target Neighborhood Hits	150	Shared Neighborhood Hits	76
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

DOC2A_HUMAN
NC score	0.440654 (rank : 29)	θ value	6.64225e-11 (rank : 35)
Query Neighborhood Hits	181	Target Neighborhood Hits	144	Shared Neighborhood Hits	75
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

DOC2A_MOUSE
NC score	0.440270 (rank : 30)	θ value	3.89403e-11 (rank : 33)
Query Neighborhood Hits	181	Target Neighborhood Hits	140	Shared Neighborhood Hits	74
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

DOC2B_MOUSE
NC score	0.439950 (rank : 31)	θ value	8.67504e-11 (rank : 36)
Query Neighborhood Hits	181	Target Neighborhood Hits	169	Shared Neighborhood Hits	76
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

RP3A_HUMAN
NC score	0.432198 (rank : 32)	θ value	1.74796e-11 (rank : 30)
Query Neighborhood Hits	181	Target Neighborhood Hits	305	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SYT7_MOUSE
NC score	0.428274 (rank : 33)	θ value	9.26847e-13 (rank : 27)
Query Neighborhood Hits	181	Target Neighborhood Hits	137	Shared Neighborhood Hits	75
SwissProt Accessions	Q9R0N7	Gene names	Syt7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

FA62A_MOUSE
NC score	0.426297 (rank : 34)	θ value	2.43908e-13 (rank : 24)
Query Neighborhood Hits	181	Target Neighborhood Hits	155	Shared Neighborhood Hits	76
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

RP3A_MOUSE
NC score	0.426125 (rank : 35)	θ value	3.89403e-11 (rank : 34)
Query Neighborhood Hits	181	Target Neighborhood Hits	510	Shared Neighborhood Hits	88
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

DOC2G_MOUSE
NC score	0.424130 (rank : 36)	θ value	3.08544e-08 (rank : 47)
Query Neighborhood Hits	181	Target Neighborhood Hits	125	Shared Neighborhood Hits	71
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

FA62A_HUMAN
NC score	0.413912 (rank : 37)	θ value	5.62301e-10 (rank : 38)
Query Neighborhood Hits	181	Target Neighborhood Hits	168	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

SYT12_HUMAN
NC score	0.413723 (rank : 38)	θ value	6.87365e-08 (rank : 53)
Query Neighborhood Hits	181	Target Neighborhood Hits	100	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IV01	Gene names	SYT12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT7_HUMAN
NC score	0.413489 (rank : 39)	θ value	1.53129e-07 (rank : 60)
Query Neighborhood Hits	181	Target Neighborhood Hits	137	Shared Neighborhood Hits	75
SwissProt Accessions	O43581	Gene names	SYT7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

SYT15_HUMAN
NC score	0.412225 (rank : 40)	θ value	8.97725e-08 (rank : 54)
Query Neighborhood Hits	181	Target Neighborhood Hits	112	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BQS2, Q7Z439, Q7Z440	Gene names	SYT15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV) (Chr10Syt).

SYT12_MOUSE
NC score	0.411955 (rank : 41)	θ value	1.53129e-07 (rank : 58)
Query Neighborhood Hits	181	Target Neighborhood Hits	102	Shared Neighborhood Hits	69
SwissProt Accessions	Q920N7	Gene names	Syt12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT5_HUMAN
NC score	0.411885 (rank : 42)	θ value	2.36244e-08 (rank : 46)
Query Neighborhood Hits	181	Target Neighborhood Hits	138	Shared Neighborhood Hits	76
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

SYT2_MOUSE
NC score	0.410418 (rank : 43)	θ value	1.17247e-07 (rank : 55)
Query Neighborhood Hits	181	Target Neighborhood Hits	143	Shared Neighborhood Hits	76
SwissProt Accessions	P46097, Q8R0E1	Gene names	Syt2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT2_HUMAN
NC score	0.410294 (rank : 44)	θ value	1.53129e-07 (rank : 59)
Query Neighborhood Hits	181	Target Neighborhood Hits	142	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N9I0, Q496K5, Q8NBE5	Gene names	SYT2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT1_HUMAN
NC score	0.407891 (rank : 45)	θ value	1.80886e-08 (rank : 44)
Query Neighborhood Hits	181	Target Neighborhood Hits	150	Shared Neighborhood Hits	76
SwissProt Accessions	P21579	Gene names	SYT1, SYT
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT1_MOUSE
NC score	0.407886 (rank : 46)	θ value	1.80886e-08 (rank : 45)
Query Neighborhood Hits	181	Target Neighborhood Hits	150	Shared Neighborhood Hits	76
SwissProt Accessions	P46096	Gene names	Syt1
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT6_MOUSE
NC score	0.407839 (rank : 47)	θ value	4.30538e-10 (rank : 37)
Query Neighborhood Hits	181	Target Neighborhood Hits	132	Shared Neighborhood Hits	75
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT6_HUMAN
NC score	0.405992 (rank : 48)	θ value	1.63604e-09 (rank : 39)
Query Neighborhood Hits	181	Target Neighborhood Hits	138	Shared Neighborhood Hits	75
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT3_HUMAN
NC score	0.404797 (rank : 49)	θ value	1.17247e-07 (rank : 56)
Query Neighborhood Hits	181	Target Neighborhood Hits	145	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BQG1, Q8N5Z1, Q8N640	Gene names	SYT3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT3_MOUSE
NC score	0.403354 (rank : 50)	θ value	3.41135e-07 (rank : 61)
Query Neighborhood Hits	181	Target Neighborhood Hits	147	Shared Neighborhood Hits	75
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT5_MOUSE
NC score	0.403132 (rank : 51)	θ value	2.88788e-06 (rank : 64)
Query Neighborhood Hits	181	Target Neighborhood Hits	140	Shared Neighborhood Hits	76
SwissProt Accessions	Q9R0N5	Gene names	Syt5, Syt9
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin IX).

SYT4_HUMAN
NC score	0.398726 (rank : 52)	θ value	6.43352e-06 (rank : 67)
Query Neighborhood Hits	181	Target Neighborhood Hits	121	Shared Neighborhood Hits	74
SwissProt Accessions	Q9H2B2, Q9P2K4	Gene names	SYT4, KIAA1342
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

SYT10_HUMAN
NC score	0.398379 (rank : 53)	θ value	6.87365e-08 (rank : 51)
Query Neighborhood Hits	181	Target Neighborhood Hits	134	Shared Neighborhood Hits	75
SwissProt Accessions	Q6XYQ8	Gene names	SYT10
Domain Architecture	No domain graphic available
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT10_MOUSE
NC score	0.398307 (rank : 54)	θ value	6.87365e-08 (rank : 52)
Query Neighborhood Hits	181	Target Neighborhood Hits	133	Shared Neighborhood Hits	76
SwissProt Accessions	Q9R0N4	Gene names	Syt10
Domain Architecture
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT4_MOUSE
NC score	0.396537 (rank : 55)	θ value	6.43352e-06 (rank : 68)
Query Neighborhood Hits	181	Target Neighborhood Hits	123	Shared Neighborhood Hits	74
SwissProt Accessions	P40749, Q3UFC1, Q8BGH3, Q8BRL6	Gene names	Syt4, Syt3
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

SYT11_MOUSE
NC score	0.396382 (rank : 56)	θ value	0.000121331 (rank : 78)
Query Neighborhood Hits	181	Target Neighborhood Hits	116	Shared Neighborhood Hits	75
SwissProt Accessions	Q9R0N3	Gene names	Syt11
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT11_HUMAN
NC score	0.395769 (rank : 57)	θ value	0.000121331 (rank : 77)
Query Neighborhood Hits	181	Target Neighborhood Hits	113	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BT88, Q14998, Q68CT5, Q8IXU3, Q96SU2	Gene names	SYT11, KIAA0080
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

RIMS1_HUMAN
NC score	0.395278 (rank : 58)	θ value	2.28291e-11 (rank : 31)
Query Neighborhood Hits	181	Target Neighborhood Hits	437	Shared Neighborhood Hits	77
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

SYT9_HUMAN
NC score	0.394496 (rank : 59)	θ value	8.40245e-06 (rank : 71)
Query Neighborhood Hits	181	Target Neighborhood Hits	144	Shared Neighborhood Hits	76
SwissProt Accessions	Q86SS6	Gene names	SYT9
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX).

RIMS4_MOUSE
NC score	0.393731 (rank : 60)	θ value	5.26297e-08 (rank : 49)
Query Neighborhood Hits	181	Target Neighborhood Hits	76	Shared Neighborhood Hits	71
SwissProt Accessions	P60191	Gene names	Rims4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

SYT9_MOUSE
NC score	0.392998 (rank : 61)	θ value	6.43352e-06 (rank : 69)
Query Neighborhood Hits	181	Target Neighborhood Hits	148	Shared Neighborhood Hits	76
SwissProt Accessions	Q9R0N9, Q8C280	Gene names	Syt9, Syt5
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V).

RIMS4_HUMAN
NC score	0.392363 (rank : 62)	θ value	5.26297e-08 (rank : 48)
Query Neighborhood Hits	181	Target Neighborhood Hits	76	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H426, Q5JWT7	Gene names	RIMS4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

SYT15_MOUSE
NC score	0.382326 (rank : 63)	θ value	0.000158464 (rank : 79)
Query Neighborhood Hits	181	Target Neighborhood Hits	100	Shared Neighborhood Hits	74
SwissProt Accessions	Q8C6N3, Q7TN81, Q7TN82, Q8C999	Gene names	Syt15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV).

RIMS2_HUMAN
NC score	0.380288 (rank : 64)	θ value	1.53129e-07 (rank : 57)
Query Neighborhood Hits	181	Target Neighborhood Hits	342	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
NC score	0.376674 (rank : 65)	θ value	6.87365e-08 (rank : 50)
Query Neighborhood Hits	181	Target Neighborhood Hits	376	Shared Neighborhood Hits	75
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

SYT8_MOUSE
NC score	0.369752 (rank : 66)	θ value	0.0148317 (rank : 86)
Query Neighborhood Hits	181	Target Neighborhood Hits	94	Shared Neighborhood Hits	68
SwissProt Accessions	Q9R0N6, Q64366, Q8C6E7	Gene names	Syt8
Domain Architecture
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

FRAP_MOUSE
NC score	0.356567 (rank : 67)	θ value	6.21693e-09 (rank : 43)
Query Neighborhood Hits	181	Target Neighborhood Hits	77	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JLN9, Q811J5, Q9CST1	Gene names	Frap1, Frap
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

FRAP_HUMAN
NC score	0.355569 (rank : 68)	θ value	6.21693e-09 (rank : 42)
Query Neighborhood Hits	181	Target Neighborhood Hits	83	Shared Neighborhood Hits	29
SwissProt Accessions	P42345, Q6LE87, Q96QG3, Q9Y4I3	Gene names	FRAP1, FRAP, FRAP2
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

PCLO_HUMAN
NC score	0.319409 (rank : 69)	θ value	2.88119e-14 (rank : 20)
Query Neighborhood Hits	181	Target Neighborhood Hits	2046	Shared Neighborhood Hits	111
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RIMS3_HUMAN
NC score	0.313270 (rank : 70)	θ value	0.47712 (rank : 97)
Query Neighborhood Hits	181	Target Neighborhood Hits	66	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UJD0, Q92511	Gene names	RIMS3, KIAA0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RIMS3_MOUSE
NC score	0.308750 (rank : 71)	θ value	0.47712 (rank : 98)
Query Neighborhood Hits	181	Target Neighborhood Hits	67	Shared Neighborhood Hits	65
SwissProt Accessions	Q80U57	Gene names	Rims3, Kiaa0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

PRKDC_MOUSE
NC score	0.308168 (rank : 72)	θ value	0.00134147 (rank : 83)
Query Neighborhood Hits	181	Target Neighborhood Hits	92	Shared Neighborhood Hits	29
SwissProt Accessions	P97313, O88187, P97928, Q307W9, Q3V2W8, Q8C2A7, Q9Z341	Gene names	Prkdc, Xrcc7
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (P460).

PRKDC_HUMAN
NC score	0.299951 (rank : 73)	θ value	0.000786445 (rank : 81)
Query Neighborhood Hits	181	Target Neighborhood Hits	93	Shared Neighborhood Hits	28
SwissProt Accessions	P78527, P78528, Q13327, Q13337, Q14175, Q59H99, Q7Z611, Q96SE6, Q9UME3	Gene names	PRKDC
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (DNPK1) (p460).

PCLO_MOUSE
NC score	0.299274 (rank : 74)	θ value	2.0648e-12 (rank : 29)
Query Neighborhood Hits	181	Target Neighborhood Hits	2275	Shared Neighborhood Hits	117
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

ATR_MOUSE
NC score	0.288746 (rank : 75)	θ value	6.43352e-06 (rank : 66)
Query Neighborhood Hits	181	Target Neighborhood Hits	63	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JKK8	Gene names	Atr
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein).

ATR_HUMAN
NC score	0.288660 (rank : 76)	θ value	1.87187e-05 (rank : 72)
Query Neighborhood Hits	181	Target Neighborhood Hits	71	Shared Neighborhood Hits	28
SwissProt Accessions	Q13535, Q7KYL3, Q93051, Q9BXK4	Gene names	ATR, FRP1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) (FRAP-related protein 1).

SYT13_MOUSE
NC score	0.282195 (rank : 77)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	181	Target Neighborhood Hits	69	Shared Neighborhood Hits	59
SwissProt Accessions	Q9EQT6, Q6ZPR2, Q8BRK6	Gene names	Syt13, Kiaa1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

SYT13_HUMAN
NC score	0.277556 (rank : 78)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	181	Target Neighborhood Hits	76	Shared Neighborhood Hits	57
SwissProt Accessions	Q7L8C5, Q9BQS3, Q9H041, Q9P2C0	Gene names	SYT13, KIAA1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

SYT14_HUMAN
NC score	0.271263 (rank : 79)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	181	Target Neighborhood Hits	81	Shared Neighborhood Hits	53
SwissProt Accessions	Q8NB59, Q5THX7, Q707N3, Q707N4, Q707N5, Q707N6, Q707N7	Gene names	SYT14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

SYT14_MOUSE
NC score	0.270836 (rank : 80)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	181	Target Neighborhood Hits	82	Shared Neighborhood Hits	55
SwissProt Accessions	Q7TN84	Gene names	Syt14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

ATM_HUMAN
NC score	0.250589 (rank : 81)	θ value	1.06291 (rank : 109)
Query Neighborhood Hits	181	Target Neighborhood Hits	78	Shared Neighborhood Hits	29
SwissProt Accessions	Q13315, O15429, Q12758, Q16551, Q93007, Q9NP02, Q9UCX7	Gene names	ATM
Domain Architecture
Description	Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T, mutated).

RASL2_HUMAN
NC score	0.248073 (rank : 82)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	181	Target Neighborhood Hits	161	Shared Neighborhood Hits	70
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

ATM_MOUSE
NC score	0.241132 (rank : 83)	θ value	3.0926 (rank : 133)
Query Neighborhood Hits	181	Target Neighborhood Hits	93	Shared Neighborhood Hits	28
SwissProt Accessions	Q62388	Gene names	Atm
Domain Architecture
Description	Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated homolog) (A-T, mutated homolog).

SMG1_MOUSE
NC score	0.230069 (rank : 84)	θ value	0.00509761 (rank : 85)
Query Neighborhood Hits	181	Target Neighborhood Hits	212	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BKX6, Q5DU42, Q6ZQC0, Q8BLU4, Q8BWJ5, Q8BXD3	Gene names	Smg1, Kiaa0421
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1).

SMG1_HUMAN
NC score	0.228376 (rank : 85)	θ value	0.00509761 (rank : 84)
Query Neighborhood Hits	181	Target Neighborhood Hits	231	Shared Neighborhood Hits	31
SwissProt Accessions	Q96Q15, O43305, Q13284, Q8NFX2, Q96QV0, Q96RW3	Gene names	SMG1, ATX, KIAA0421, LIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1) (hSMG-1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (61E3.4).

UN13D_HUMAN
NC score	0.201809 (rank : 86)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	181	Target Neighborhood Hits	117	Shared Neighborhood Hits	63
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

RASA3_HUMAN
NC score	0.193773 (rank : 87)	θ value	0.00035302 (rank : 80)
Query Neighborhood Hits	181	Target Neighborhood Hits	166	Shared Neighborhood Hits	69
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

K0528_HUMAN
NC score	0.192350 (rank : 88)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	181	Target Neighborhood Hits	96	Shared Neighborhood Hits	59
SwissProt Accessions	Q86YS7, O60280, Q7Z619, Q86SU3	Gene names	KIAA0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

K0528_MOUSE
NC score	0.192255 (rank : 89)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	181	Target Neighborhood Hits	102	Shared Neighborhood Hits	59
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

BAIP3_HUMAN
NC score	0.191584 (rank : 90)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	181	Target Neighborhood Hits	108	Shared Neighborhood Hits	63
SwissProt Accessions	O94812, O94839, Q2M226, Q658J2, Q76N05, Q96RZ3, Q9UJK1	Gene names	BAIAP3, KIAA0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

RASL1_HUMAN
NC score	0.190052 (rank : 91)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	181	Target Neighborhood Hits	142	Shared Neighborhood Hits	62
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

BAIP3_MOUSE
NC score	0.189491 (rank : 92)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	181	Target Neighborhood Hits	112	Shared Neighborhood Hits	61
SwissProt Accessions	Q80TT2, Q6RUT4	Gene names	Baiap3, Gm937, Kiaa0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

RASA2_MOUSE
NC score	0.186492 (rank : 93)	θ value	0.365318 (rank : 95)
Query Neighborhood Hits	181	Target Neighborhood Hits	159	Shared Neighborhood Hits	66
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RASL1_MOUSE
NC score	0.183488 (rank : 94)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	181	Target Neighborhood Hits	148	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

RASA2_HUMAN
NC score	0.182493 (rank : 95)	θ value	1.81305 (rank : 119)
Query Neighborhood Hits	181	Target Neighborhood Hits	157	Shared Neighborhood Hits	68
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

DYSF_HUMAN
NC score	0.159354 (rank : 96)	θ value	2.36792 (rank : 124)
Query Neighborhood Hits	181	Target Neighborhood Hits	170	Shared Neighborhood Hits	74
SwissProt Accessions	O75923, O75696, Q9UEN7	Gene names	DYSF, FER1L1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

DYSF_MOUSE
NC score	0.154165 (rank : 97)	θ value	2.36792 (rank : 125)
Query Neighborhood Hits	181	Target Neighborhood Hits	162	Shared Neighborhood Hits	73
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

RGS3_HUMAN
NC score	0.151266 (rank : 98)	θ value	0.000121331 (rank : 76)
Query Neighborhood Hits	181	Target Neighborhood Hits	1375	Shared Neighborhood Hits	96
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

NED4L_HUMAN
NC score	0.145008 (rank : 99)	θ value	0.62314 (rank : 100)
Query Neighborhood Hits	181	Target Neighborhood Hits	238	Shared Neighborhood Hits	72
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

UN13B_MOUSE
NC score	0.144691 (rank : 100)	θ value	1.38821 (rank : 116)
Query Neighborhood Hits	181	Target Neighborhood Hits	210	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13B_HUMAN
NC score	0.143872 (rank : 101)	θ value	0.813845 (rank : 108)
Query Neighborhood Hits	181	Target Neighborhood Hits	217	Shared Neighborhood Hits	61
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

NED4L_MOUSE
NC score	0.142542 (rank : 102)	θ value	0.62314 (rank : 101)
Query Neighborhood Hits	181	Target Neighborhood Hits	231	Shared Neighborhood Hits	71
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

MYOF_HUMAN
NC score	0.138684 (rank : 103)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	181	Target Neighborhood Hits	147	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NZM1, Q9HBU3, Q9NZM0, Q9ULL3, Q9Y4U4	Gene names	FER1L3, KIAA1207, MYOF
Domain Architecture
Description	Myoferlin (Fer-1-like protein 3).

TAC2N_HUMAN
NC score	0.137262 (rank : 104)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	181	Target Neighborhood Hits	47	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N9U0	Gene names	MTAC2D1, C14orf47
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

TAC2N_MOUSE
NC score	0.136994 (rank : 105)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	181	Target Neighborhood Hits	43	Shared Neighborhood Hits	34
SwissProt Accessions	Q91XT6, Q9D4A0	Gene names	Mtac2d1
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

UN13A_HUMAN
NC score	0.134477 (rank : 106)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	181	Target Neighborhood Hits	285	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

NEDD4_HUMAN
NC score	0.133541 (rank : 107)	θ value	1.38821 (rank : 114)
Query Neighborhood Hits	181	Target Neighborhood Hits	214	Shared Neighborhood Hits	69
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

PA24D_MOUSE
NC score	0.130200 (rank : 108)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	181	Target Neighborhood Hits	100	Shared Neighborhood Hits	60
SwissProt Accessions	Q50L43, Q3TJC5	Gene names	Pla2g4d
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

RASA3_MOUSE
NC score	0.129704 (rank : 109)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	181	Target Neighborhood Hits	144	Shared Neighborhood Hits	63
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

RFIP2_HUMAN
NC score	0.125657 (rank : 110)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	181	Target Neighborhood Hits	97	Shared Neighborhood Hits	53
SwissProt Accessions	Q7L804, Q9Y2F0	Gene names	RAB11FIP2, KIAA0941
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11).

NEDD4_MOUSE
NC score	0.122855 (rank : 111)	θ value	6.88961 (rank : 165)
Query Neighborhood Hits	181	Target Neighborhood Hits	212	Shared Neighborhood Hits	68
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

OTOF_HUMAN
NC score	0.117026 (rank : 112)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	181	Target Neighborhood Hits	168	Shared Neighborhood Hits	57
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

OTOF_MOUSE
NC score	0.115365 (rank : 113)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	181	Target Neighborhood Hits	196	Shared Neighborhood Hits	58
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

KPCG_MOUSE
NC score	0.115203 (rank : 114)	θ value	1.87187e-05 (rank : 73)
Query Neighborhood Hits	181	Target Neighborhood Hits	1123	Shared Neighborhood Hits	78
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCG_HUMAN
NC score	0.114024 (rank : 115)	θ value	4.1701e-05 (rank : 74)
Query Neighborhood Hits	181	Target Neighborhood Hits	1126	Shared Neighborhood Hits	78
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

PA24D_HUMAN
NC score	0.111659 (rank : 116)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	181	Target Neighborhood Hits	97	Shared Neighborhood Hits	57
SwissProt Accessions	Q86XP0, Q8N176	Gene names	PLA2G4D
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

KPCA_HUMAN
NC score	0.110445 (rank : 117)	θ value	4.45536e-07 (rank : 62)
Query Neighborhood Hits	181	Target Neighborhood Hits	1070	Shared Neighborhood Hits	78
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

NCF1_HUMAN
NC score	0.108895 (rank : 118)	θ value	7.1131e-05 (rank : 75)
Query Neighborhood Hits	181	Target Neighborhood Hits	198	Shared Neighborhood Hits	10
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

KPCA_MOUSE
NC score	0.107232 (rank : 119)	θ value	4.92598e-06 (rank : 65)
Query Neighborhood Hits	181	Target Neighborhood Hits	1067	Shared Neighborhood Hits	78
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCB_HUMAN
NC score	0.106207 (rank : 120)	θ value	2.21117e-06 (rank : 63)
Query Neighborhood Hits	181	Target Neighborhood Hits	1121	Shared Neighborhood Hits	78
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCB_MOUSE
NC score	0.105910 (rank : 121)	θ value	8.40245e-06 (rank : 70)
Query Neighborhood Hits	181	Target Neighborhood Hits	1117	Shared Neighborhood Hits	77
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

NCF1_MOUSE
NC score	0.099993 (rank : 122)	θ value	0.00134147 (rank : 82)
Query Neighborhood Hits	181	Target Neighborhood Hits	198	Shared Neighborhood Hits	9
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

PA24B_MOUSE
NC score	0.093936 (rank : 123)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	181	Target Neighborhood Hits	102	Shared Neighborhood Hits	52
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

SNX16_MOUSE
NC score	0.089877 (rank : 124)	θ value	0.125558 (rank : 93)
Query Neighborhood Hits	181	Target Neighborhood Hits	82	Shared Neighborhood Hits	19
SwissProt Accessions	Q8C080	Gene names	Snx16
Domain Architecture	No domain graphic available
Description	Sorting nexin-16.

SNX16_HUMAN
NC score	0.089263 (rank : 125)	θ value	0.0330416 (rank : 90)
Query Neighborhood Hits	181	Target Neighborhood Hits	110	Shared Neighborhood Hits	20
SwissProt Accessions	P57768, Q8N4U3	Gene names	SNX16
Domain Architecture
Description	Sorting nexin-16.

PA24E_MOUSE
NC score	0.088863 (rank : 126)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	181	Target Neighborhood Hits	95	Shared Neighborhood Hits	55
SwissProt Accessions	Q50L42, Q8BX44	Gene names	Pla2g4e
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

MYRIP_MOUSE
NC score	0.082403 (rank : 127)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	181	Target Neighborhood Hits	207	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

CPNE3_HUMAN
NC score	0.082230 (rank : 128)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	181	Target Neighborhood Hits	90	Shared Neighborhood Hits	45
SwissProt Accessions	O75131, Q8IYA1	Gene names	CPNE3, CPN3, KIAA0636
Domain Architecture
Description	Copine-3 (Copine III).

CPNE3_MOUSE
NC score	0.081623 (rank : 129)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	181	Target Neighborhood Hits	90	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BT60, Q5CZX9, Q5DU22	Gene names	Cpne3, Kiaa0636
Domain Architecture
Description	Copine-3 (Copine III).

PA24A_MOUSE
NC score	0.080411 (rank : 130)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	181	Target Neighborhood Hits	100	Shared Neighborhood Hits	56
SwissProt Accessions	P47713	Gene names	Pla2g4a, Cpla2, Pla2g4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

MYRIP_HUMAN
NC score	0.079493 (rank : 131)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	181	Target Neighborhood Hits	269	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

PA24E_HUMAN
NC score	0.079315 (rank : 132)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	181	Target Neighborhood Hits	89	Shared Neighborhood Hits	53
SwissProt Accessions	Q3MJ16, Q6ZSC0	Gene names	PLA2G4E
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

MELPH_MOUSE
NC score	0.078271 (rank : 133)	θ value	6.88961 (rank : 163)
Query Neighborhood Hits	181	Target Neighborhood Hits	112	Shared Neighborhood Hits	14
SwissProt Accessions	Q91V27, Q99N53	Gene names	Mlph, Ln, Slac2a
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Leaden protein) (Synaptotagmin-like protein 2a) (Slac2-a) (Slp homolog lacking C2 domains a).

PA24A_HUMAN
NC score	0.076292 (rank : 134)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	181	Target Neighborhood Hits	88	Shared Neighborhood Hits	57
SwissProt Accessions	P47712	Gene names	PLA2G4A, CPLA2, PLA2G4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

MELPH_HUMAN
NC score	0.075291 (rank : 135)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	181	Target Neighborhood Hits	145	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BV36, Q9HA71	Gene names	MLPH, SLAC2A
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Synaptotagmin-like protein 2a) (Slp homolog lacking C2 domains a).

CPNE5_MOUSE
NC score	0.074845 (rank : 136)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	181	Target Neighborhood Hits	86	Shared Neighborhood Hits	47
SwissProt Accessions	Q8JZW4	Gene names	Cpne5
Domain Architecture
Description	Copine-5 (Copine V).

CPNE5_HUMAN
NC score	0.074732 (rank : 137)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	181	Target Neighborhood Hits	88	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HCH3	Gene names	CPNE5, KIAA1599
Domain Architecture
Description	Copine-5 (Copine V).

PA24B_HUMAN
NC score	0.073482 (rank : 138)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	181	Target Neighborhood Hits	89	Shared Neighborhood Hits	47
SwissProt Accessions	O95712, Q59GF9, Q8TB10, Q9UKV7	Gene names	PLA2G4B
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

CPNE1_MOUSE
NC score	0.071782 (rank : 139)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	181	Target Neighborhood Hits	83	Shared Neighborhood Hits	48
SwissProt Accessions	Q8C166, Q925K4, Q925K5	Gene names	Cpne1
Domain Architecture
Description	Copine-1 (Copine I).

CPNE2_MOUSE
NC score	0.071389 (rank : 140)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	181	Target Neighborhood Hits	82	Shared Neighborhood Hits	47
SwissProt Accessions	P59108, Q8K1D7	Gene names	Cpne2
Domain Architecture
Description	Copine-2 (Copine II).

CPNE2_HUMAN
NC score	0.071255 (rank : 141)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	181	Target Neighborhood Hits	75	Shared Neighborhood Hits	44
SwissProt Accessions	Q96FN4, Q68D19, Q86XP9	Gene names	CPNE2
Domain Architecture
Description	Copine-2 (Copine II).

CPNE8_HUMAN
NC score	0.070296 (rank : 142)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	181	Target Neighborhood Hits	86	Shared Neighborhood Hits	48
SwissProt Accessions	Q86YQ8, Q2TB41	Gene names	CPNE8
Domain Architecture
Description	Copine-8 (Copine VIII).

CPNE8_MOUSE
NC score	0.068707 (rank : 143)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	181	Target Neighborhood Hits	85	Shared Neighborhood Hits	48
SwissProt Accessions	Q9DC53, Q9CUZ8	Gene names	Cpne8
Domain Architecture
Description	Copine-8 (Copine VIII).

ITSN2_HUMAN
NC score	0.067425 (rank : 144)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	181	Target Neighborhood Hits	1173	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

CPNE7_HUMAN
NC score	0.066872 (rank : 145)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	181	Target Neighborhood Hits	92	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UBL6	Gene names	CPNE7
Domain Architecture
Description	Copine-7 (Copine VII).

ITSN2_MOUSE
NC score	0.060442 (rank : 146)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	181	Target Neighborhood Hits	1371	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

CPNE1_HUMAN
NC score	0.059674 (rank : 147)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	181	Target Neighborhood Hits	70	Shared Neighborhood Hits	45
SwissProt Accessions	Q99829, Q6IBL3, Q9H243, Q9NTZ7	Gene names	CPNE1, CPN1
Domain Architecture
Description	Copine-1 (Copine I).

PA24F_MOUSE
NC score	0.058477 (rank : 148)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	181	Target Neighborhood Hits	93	Shared Neighborhood Hits	48
SwissProt Accessions	Q50L41, Q80VQ8, Q80VV9	Gene names	Pla2g4f
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

CPNE6_HUMAN
NC score	0.056257 (rank : 149)	θ value	3.0926 (rank : 134)
Query Neighborhood Hits	181	Target Neighborhood Hits	85	Shared Neighborhood Hits	47
SwissProt Accessions	O95741, Q53HA6, Q8WVG1	Gene names	CPNE6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

TFG_HUMAN
NC score	0.054220 (rank : 150)	θ value	2.36792 (rank : 132)
Query Neighborhood Hits	181	Target Neighborhood Hits	122	Shared Neighborhood Hits	13
SwissProt Accessions	Q92734, Q15656	Gene names	TFG
Domain Architecture
Description	Protein TFG (TRK-fused gene protein).

PLCD1_HUMAN
NC score	0.054199 (rank : 151)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	181	Target Neighborhood Hits	93	Shared Neighborhood Hits	40
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

RFIP1_MOUSE
NC score	0.053725 (rank : 152)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	181	Target Neighborhood Hits	152	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

SPT5H_HUMAN
NC score	0.052415 (rank : 153)	θ value	0.0252991 (rank : 87)
Query Neighborhood Hits	181	Target Neighborhood Hits	436	Shared Neighborhood Hits	26
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

NOXO1_MOUSE
NC score	0.052140 (rank : 154)	θ value	1.81305 (rank : 118)
Query Neighborhood Hits	181	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

CPNE6_MOUSE
NC score	0.051992 (rank : 155)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	181	Target Neighborhood Hits	87	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Z140	Gene names	Cpne6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

SPT5H_MOUSE
NC score	0.051780 (rank : 156)	θ value	0.0252991 (rank : 88)
Query Neighborhood Hits	181	Target Neighborhood Hits	437	Shared Neighborhood Hits	25
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

WWC1_MOUSE
NC score	0.050512 (rank : 157)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	181	Target Neighborhood Hits	290	Shared Neighborhood Hits	31
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

BSN_MOUSE
NC score	0.049889 (rank : 158)	θ value	6.88961 (rank : 156)
Query Neighborhood Hits	181	Target Neighborhood Hits	2057	Shared Neighborhood Hits	47
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

NCF4_HUMAN
NC score	0.047560 (rank : 159)	θ value	0.163984 (rank : 94)
Query Neighborhood Hits	181	Target Neighborhood Hits	161	Shared Neighborhood Hits	17
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

SNX18_HUMAN
NC score	0.045491 (rank : 160)	θ value	1.81305 (rank : 120)
Query Neighborhood Hits	181	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SNX18_MOUSE
NC score	0.042412 (rank : 161)	θ value	1.81305 (rank : 121)
Query Neighborhood Hits	181	Target Neighborhood Hits	198	Shared Neighborhood Hits	14
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SNX24_HUMAN
NC score	0.041775 (rank : 162)	θ value	1.81305 (rank : 122)
Query Neighborhood Hits	181	Target Neighborhood Hits	42	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y343, Q6UY33	Gene names	SNX24
Domain Architecture
Description	Sorting nexin-24.

SNX24_MOUSE
NC score	0.040872 (rank : 163)	θ value	2.36792 (rank : 131)
Query Neighborhood Hits	181	Target Neighborhood Hits	40	Shared Neighborhood Hits	11
SwissProt Accessions	Q9CRB0	Gene names	Snx24
Domain Architecture	No domain graphic available
Description	Sorting nexin-24.

PO121_HUMAN
NC score	0.039912 (rank : 164)	θ value	1.06291 (rank : 110)
Query Neighborhood Hits	181	Target Neighborhood Hits	344	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PO121_MOUSE
NC score	0.037634 (rank : 165)	θ value	1.06291 (rank : 111)
Query Neighborhood Hits	181	Target Neighborhood Hits	345	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

SNX25_HUMAN
NC score	0.034073 (rank : 166)	θ value	1.81305 (rank : 123)
Query Neighborhood Hits	181	Target Neighborhood Hits	77	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H3E2	Gene names	SNX25
Domain Architecture
Description	Sorting nexin-25.

RPB1_MOUSE
NC score	0.032731 (rank : 167)	θ value	0.813845 (rank : 105)
Query Neighborhood Hits	181	Target Neighborhood Hits	363	Shared Neighborhood Hits	16
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_HUMAN
NC score	0.032512 (rank : 168)	θ value	0.813845 (rank : 104)
Query Neighborhood Hits	181	Target Neighborhood Hits	362	Shared Neighborhood Hits	16
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

ACY2_MOUSE
NC score	0.030391 (rank : 169)	θ value	0.0431538 (rank : 91)
Query Neighborhood Hits	181	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R3P0, Q9D876, Q9DCE2, Q9JIN8	Gene names	Aspa
Domain Architecture
Description	Aspartoacylase (EC 3.5.1.15) (Aminoacylase-2) (ACY-2).

AUTS2_HUMAN
NC score	0.029820 (rank : 170)	θ value	4.03905 (rank : 136)
Query Neighborhood Hits	181	Target Neighborhood Hits	342	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

SNX14_HUMAN
NC score	0.029594 (rank : 171)	θ value	6.88961 (rank : 169)
Query Neighborhood Hits	181	Target Neighborhood Hits	77	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y5W7, Q9BSD1	Gene names	SNX14
Domain Architecture
Description	Sorting nexin-14.

TP53B_HUMAN
NC score	0.029455 (rank : 172)	θ value	5.27518 (rank : 154)
Query Neighborhood Hits	181	Target Neighborhood Hits	413	Shared Neighborhood Hits	16
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

SNX14_MOUSE
NC score	0.028975 (rank : 173)	θ value	8.99809 (rank : 178)
Query Neighborhood Hits	181	Target Neighborhood Hits	75	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BHY8	Gene names	Snx14
Domain Architecture	No domain graphic available
Description	Sorting nexin-14.

K0562_HUMAN
NC score	0.026947 (rank : 174)	θ value	1.81305 (rank : 117)
Query Neighborhood Hits	181	Target Neighborhood Hits	146	Shared Neighborhood Hits	7
SwissProt Accessions	O60308, Q5JSQ3, Q5SR24, Q5SR25, Q6PKF5, Q86W32, Q86X14	Gene names	KIAA0562
Domain Architecture	No domain graphic available
Description	Protein KIAA0562.

CCNK_MOUSE
NC score	0.026666 (rank : 175)	θ value	0.47712 (rank : 96)
Query Neighborhood Hits	181	Target Neighborhood Hits	350	Shared Neighborhood Hits	19
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

SNX13_MOUSE
NC score	0.025275 (rank : 176)	θ value	2.36792 (rank : 130)
Query Neighborhood Hits	181	Target Neighborhood Hits	86	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PHS6	Gene names	Snx13
Domain Architecture	No domain graphic available
Description	Sorting nexin-13.

PRRT3_HUMAN
NC score	0.023503 (rank : 177)	θ value	5.27518 (rank : 150)
Query Neighborhood Hits	181	Target Neighborhood Hits	998	Shared Neighborhood Hits	33
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SGK3_MOUSE
NC score	0.023300 (rank : 178)	θ value	0.0330416 (rank : 89)
Query Neighborhood Hits	181	Target Neighborhood Hits	882	Shared Neighborhood Hits	23
SwissProt Accessions	Q9ERE3, Q3UAY2	Gene names	Sgk3, Cisk, Sgkl
Domain Architecture
Description	Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid- regulated kinase-like) (Cytokine-independent survival kinase).

SGK3_HUMAN
NC score	0.023176 (rank : 179)	θ value	0.0431538 (rank : 92)
Query Neighborhood Hits	181	Target Neighborhood Hits	877	Shared Neighborhood Hits	24
SwissProt Accessions	Q96BR1, Q9P1Q7, Q9UKG5	Gene names	SGK3, SGKL
Domain Architecture
Description	Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid- regulated kinase-like).

RERE_MOUSE
NC score	0.022534 (rank : 180)	θ value	0.813845 (rank : 103)
Query Neighborhood Hits	181	Target Neighborhood Hits	785	Shared Neighborhood Hits	25
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

TENS1_HUMAN
NC score	0.020729 (rank : 181)	θ value	0.813845 (rank : 106)
Query Neighborhood Hits	181	Target Neighborhood Hits	400	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

MAP2_HUMAN
NC score	0.020257 (rank : 182)	θ value	0.62314 (rank : 99)
Query Neighborhood Hits	181	Target Neighborhood Hits	348	Shared Neighborhood Hits	14
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

RERE_HUMAN
NC score	0.019650 (rank : 183)	θ value	1.38821 (rank : 115)
Query Neighborhood Hits	181	Target Neighborhood Hits	779	Shared Neighborhood Hits	27
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

TULP4_MOUSE
NC score	0.017193 (rank : 184)	θ value	0.813845 (rank : 107)
Query Neighborhood Hits	181	Target Neighborhood Hits	247	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

DPYD_HUMAN
NC score	0.016965 (rank : 185)	θ value	6.88961 (rank : 158)
Query Neighborhood Hits	181	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q12882, Q16694, Q16761, Q96TH1	Gene names	DPYD
Domain Architecture
Description	Dihydropyrimidine dehydrogenase [NADP+] precursor (EC 1.3.1.2) (DPD) (DHPDHase) (Dihydrouracil dehydrogenase) (Dihydrothymine dehydrogenase).

SMRC2_HUMAN
NC score	0.015122 (rank : 186)	θ value	2.36792 (rank : 129)
Query Neighborhood Hits	181	Target Neighborhood Hits	499	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

TULP4_HUMAN
NC score	0.015044 (rank : 187)	θ value	8.99809 (rank : 180)
Query Neighborhood Hits	181	Target Neighborhood Hits	426	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

CCD95_HUMAN
NC score	0.014975 (rank : 188)	θ value	6.88961 (rank : 157)
Query Neighborhood Hits	181	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NBZ0	Gene names	CCDC95
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 95.

MEF2B_HUMAN
NC score	0.014742 (rank : 189)	θ value	2.36792 (rank : 127)
Query Neighborhood Hits	181	Target Neighborhood Hits	150	Shared Neighborhood Hits	10
SwissProt Accessions	Q02080	Gene names	MEF2B, XMEF2
Domain Architecture
Description	Myocyte-specific enhancer factor 2B (Serum response factor-like protein 2) (XMEF2) (RSRFR2).

MUC2_HUMAN
NC score	0.014103 (rank : 190)	θ value	2.36792 (rank : 128)
Query Neighborhood Hits	181	Target Neighborhood Hits	906	Shared Neighborhood Hits	25
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

SMRC2_MOUSE
NC score	0.013674 (rank : 191)	θ value	6.88961 (rank : 168)
Query Neighborhood Hits	181	Target Neighborhood Hits	487	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

TBP_HUMAN
NC score	0.012873 (rank : 192)	θ value	8.99809 (rank : 179)
Query Neighborhood Hits	181	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	P20226, Q16845, Q9UC02	Gene names	TBP, TF2D, TFIID
Domain Architecture
Description	TATA-box-binding protein (TATA-box factor) (TATA-binding factor) (TATA sequence-binding protein) (Transcription initiation factor TFIID TBP subunit).

GPTC2_MOUSE
NC score	0.012707 (rank : 193)	θ value	3.0926 (rank : 135)
Query Neighborhood Hits	181	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TQC7, Q8BNJ9, Q8BPM1, Q8CDH9	Gene names	Gpatc2
Domain Architecture
Description	G patch domain-containing protein 2.

TINF2_HUMAN
NC score	0.012532 (rank : 194)	θ value	4.03905 (rank : 143)
Query Neighborhood Hits	181	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BSI4, Q9H904, Q9UHC2	Gene names	TINF2, TIN2
Domain Architecture	No domain graphic available
Description	TERF1-interacting nuclear factor 2 (TRF1-interacting nuclear protein 2).

AP3B1_HUMAN
NC score	0.012427 (rank : 195)	θ value	8.99809 (rank : 171)
Query Neighborhood Hits	181	Target Neighborhood Hits	283	Shared Neighborhood Hits	7
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

MAML2_HUMAN
NC score	0.012415 (rank : 196)	θ value	2.36792 (rank : 126)
Query Neighborhood Hits	181	Target Neighborhood Hits	360	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

BRCA2_MOUSE
NC score	0.010973 (rank : 197)	θ value	5.27518 (rank : 146)
Query Neighborhood Hits	181	Target Neighborhood Hits	222	Shared Neighborhood Hits	14
SwissProt Accessions	P97929, O35922, P97383	Gene names	Brca2, Fancd1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein homolog (Fanconi anemia group D1 protein homolog).

GUAD_MOUSE
NC score	0.010793 (rank : 198)	θ value	8.99809 (rank : 175)
Query Neighborhood Hits	181	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R111	Gene names	Gda
Domain Architecture
Description	Guanine deaminase (EC 3.5.4.3) (Guanase) (Guanine aminase) (Guanine aminohydrolase) (GAH).

SYNJ1_HUMAN
NC score	0.010311 (rank : 199)	θ value	5.27518 (rank : 152)
Query Neighborhood Hits	181	Target Neighborhood Hits	498	Shared Neighborhood Hits	16
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

STIM2_MOUSE
NC score	0.009417 (rank : 200)	θ value	5.27518 (rank : 151)
Query Neighborhood Hits	181	Target Neighborhood Hits	403	Shared Neighborhood Hits	8
SwissProt Accessions	P83093, Q69ZI3, Q80VF4	Gene names	Stim2, Kiaa1482
Domain Architecture	No domain graphic available
Description	Stromal interaction molecule 2 precursor.

GPTC2_HUMAN
NC score	0.008942 (rank : 201)	θ value	8.99809 (rank : 174)
Query Neighborhood Hits	181	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NW75, Q86YE7	Gene names	GPATC2
Domain Architecture
Description	G patch domain-containing protein 2.

EXOS7_HUMAN
NC score	0.008697 (rank : 202)	θ value	5.27518 (rank : 147)
Query Neighborhood Hits	181	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q15024, Q96E72	Gene names	EXOSC7, KIAA0116, RRP42
Domain Architecture
Description	Exosome complex exonuclease RRP42 (EC 3.1.13.-) (Ribosomal RNA- processing protein 42) (Exosome component 7) (p8).

TIMD4_MOUSE
NC score	0.008414 (rank : 203)	θ value	5.27518 (rank : 153)
Query Neighborhood Hits	181	Target Neighborhood Hits	65	Shared Neighborhood Hits	2
SwissProt Accessions	Q6U7R4, Q6U7R3, Q8CIC7	Gene names	Timd4, Tim4
Domain Architecture	No domain graphic available
Description	T-cell immunoglobulin and mucin domain-containing protein 4 precursor (TIMD-4) (T-cell membrane protein 4) (TIM-4) (Spleen, mucin- containing, knockout of lymphotoxin protein) (SMUCKLER).

PP2CD_HUMAN
NC score	0.008372 (rank : 204)	θ value	4.03905 (rank : 141)
Query Neighborhood Hits	181	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	O15297	Gene names	PPM1D, WIP1
Domain Architecture
Description	Protein phosphatase 2C isoform delta (EC 3.1.3.16) (PP2C-delta) (p53- induced protein phosphatase 1) (Protein phosphatase magnesium- dependent 1 delta).

K1802_HUMAN
NC score	0.007682 (rank : 205)	θ value	5.27518 (rank : 148)
Query Neighborhood Hits	181	Target Neighborhood Hits	1378	Shared Neighborhood Hits	32
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MYO15_MOUSE
NC score	0.007671 (rank : 206)	θ value	5.27518 (rank : 149)
Query Neighborhood Hits	181	Target Neighborhood Hits	467	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NFIA_HUMAN
NC score	0.007299 (rank : 207)	θ value	6.88961 (rank : 166)
Query Neighborhood Hits	181	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	Q12857, Q9H3X9, Q9P2A9	Gene names	NFIA, KIAA1439
Domain Architecture
Description	Nuclear factor 1 A-type (Nuclear factor 1/A) (NF1-A) (NFI-A) (NF-I/A) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

NFIA_MOUSE
NC score	0.007269 (rank : 208)	θ value	6.88961 (rank : 167)
Query Neighborhood Hits	181	Target Neighborhood Hits	69	Shared Neighborhood Hits	5
SwissProt Accessions	Q02780, P70250, P70251, Q3UUZ2, Q61960, Q8VBT5, Q9R1G5	Gene names	Nfia
Domain Architecture
Description	Nuclear factor 1 A-type (Nuclear factor 1/A) (NF1-A) (NFI-A) (NF-I/A) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

MYCB2_MOUSE
NC score	0.007229 (rank : 209)	θ value	8.99809 (rank : 176)
Query Neighborhood Hits	181	Target Neighborhood Hits	307	Shared Neighborhood Hits	14
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

ZYX_HUMAN
NC score	0.006681 (rank : 210)	θ value	4.03905 (rank : 144)
Query Neighborhood Hits	181	Target Neighborhood Hits	387	Shared Neighborhood Hits	9
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

ZC3H6_HUMAN
NC score	0.006669 (rank : 211)	θ value	8.99809 (rank : 181)
Query Neighborhood Hits	181	Target Neighborhood Hits	228	Shared Neighborhood Hits	8
SwissProt Accessions	P61129	Gene names	ZC3H6, KIAA2035, ZC3HDC6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

INP4B_HUMAN
NC score	0.006600 (rank : 212)	θ value	6.88961 (rank : 162)
Query Neighborhood Hits	181	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	O15327, Q6IN59, Q6PJB4	Gene names	INPP4B
Domain Architecture	No domain graphic available
Description	Type II inositol-3,4-bisphosphate 4-phosphatase (EC 3.1.3.66) (Inositol polyphosphate 4-phosphatase type II).

DDX58_MOUSE
NC score	0.006215 (rank : 213)	θ value	4.03905 (rank : 137)
Query Neighborhood Hits	181	Target Neighborhood Hits	99	Shared Neighborhood Hits	2
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

ENH2_HUMAN
NC score	0.005762 (rank : 214)	θ value	8.99809 (rank : 173)
Query Neighborhood Hits	181	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	Q9N2J9	Gene names
Domain Architecture
Description	HERV-H_3q26 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p60) (HERV-H/env60) [Contains: Surface protein (SU); Transmembrane protein (TM)].

HS105_HUMAN
NC score	0.005470 (rank : 215)	θ value	6.88961 (rank : 159)
Query Neighborhood Hits	181	Target Neighborhood Hits	209	Shared Neighborhood Hits	12
SwissProt Accessions	Q92598, O95739, Q5TBM6, Q5TBM8, Q9UPC4	Gene names	HSPH1, HSP105, HSP110, KIAA0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock 110 kDa protein) (Antigen NY- CO-25).

MUC5B_HUMAN
NC score	0.005438 (rank : 216)	θ value	6.88961 (rank : 164)
Query Neighborhood Hits	181	Target Neighborhood Hits	1020	Shared Neighborhood Hits	15
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

AKAP9_HUMAN
NC score	0.003200 (rank : 217)	θ value	0.813845 (rank : 102)
Query Neighborhood Hits	181	Target Neighborhood Hits	1710	Shared Neighborhood Hits	20
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

CI093_HUMAN
NC score	0.002941 (rank : 218)	θ value	1.38821 (rank : 113)
Query Neighborhood Hits	181	Target Neighborhood Hits	1088	Shared Neighborhood Hits	15
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

SNX23_HUMAN
NC score	0.002884 (rank : 219)	θ value	4.03905 (rank : 142)
Query Neighborhood Hits	181	Target Neighborhood Hits	944	Shared Neighborhood Hits	26
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

BPAEA_HUMAN
NC score	0.002453 (rank : 220)	θ value	1.38821 (rank : 112)
Query Neighborhood Hits	181	Target Neighborhood Hits	1369	Shared Neighborhood Hits	14
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

HXA11_MOUSE
NC score	0.001270 (rank : 221)	θ value	6.88961 (rank : 161)
Query Neighborhood Hits	181	Target Neighborhood Hits	327	Shared Neighborhood Hits	7
SwissProt Accessions	P31311, Q3V026	Gene names	Hoxa11, Hox-1.9, Hoxa-11
Domain Architecture
Description	Homeobox protein Hox-A11 (Hox-1.9).

HXA11_HUMAN
NC score	0.001245 (rank : 222)	θ value	6.88961 (rank : 160)
Query Neighborhood Hits	181	Target Neighborhood Hits	334	Shared Neighborhood Hits	7
SwissProt Accessions	P31270	Gene names	HOXA11, HOX1I
Domain Architecture
Description	Homeobox protein Hox-A11 (Hox-1I).

BPA1_MOUSE
NC score	0.000602 (rank : 223)	θ value	5.27518 (rank : 145)
Query Neighborhood Hits	181	Target Neighborhood Hits	1477	Shared Neighborhood Hits	15
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

PRDM2_HUMAN
NC score	-0.000078 (rank : 224)	θ value	8.99809 (rank : 177)
Query Neighborhood Hits	181	Target Neighborhood Hits	1135	Shared Neighborhood Hits	21
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

ADA30_HUMAN
NC score	-0.000392 (rank : 225)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	181	Target Neighborhood Hits	391	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ATBF1_MOUSE
NC score	-0.001261 (rank : 226)	θ value	6.88961 (rank : 155)
Query Neighborhood Hits	181	Target Neighborhood Hits	1841	Shared Neighborhood Hits	33
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

EEA1_HUMAN
NC score	-0.001272 (rank : 227)	θ value	8.99809 (rank : 172)
Query Neighborhood Hits	181	Target Neighborhood Hits	1796	Shared Neighborhood Hits	23
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

POGZ_HUMAN
NC score	-0.001536 (rank : 228)	θ value	4.03905 (rank : 140)
Query Neighborhood Hits	181	Target Neighborhood Hits	745	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z3K3, O75049, Q8TDZ7, Q9Y4X7	Gene names	POGZ, KIAA0461
Domain Architecture
Description	Pogo transposable element with ZNF domain.

MYH11_HUMAN
NC score	-0.002390 (rank : 229)	θ value	4.03905 (rank : 139)
Query Neighborhood Hits	181	Target Neighborhood Hits	1806	Shared Neighborhood Hits	19
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

GLIS1_MOUSE
NC score	-0.003922 (rank : 230)	θ value	4.03905 (rank : 138)
Query Neighborhood Hits	181	Target Neighborhood Hits	751	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K1M4, Q6NZF6, Q8R4Z3	Gene names	Glis1, Gli5
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS1 (GLI-similar 1) (Gli homologous protein 1) (GliH1).