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Network neighborhood for query Sequence : RIMS2_MOUSE

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RIMS2_MOUSE
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RIMS1_HUMAN
θ value	0 (rank : 1)	NC score	0.940040 (rank : 3)
Query Neighborhood Hits	376	Target Neighborhood Hits	437	Shared Neighborhood Hits	230
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

RIMS2_HUMAN
θ value	0 (rank : 2)	NC score	0.987681 (rank : 2)
Query Neighborhood Hits	376	Target Neighborhood Hits	342	Shared Neighborhood Hits	290
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	376	Target Neighborhood Hits	376	Shared Neighborhood Hits	376
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

RIMS3_HUMAN
θ value	2.5344e-111 (rank : 4)	NC score	0.876783 (rank : 6)
Query Neighborhood Hits	376	Target Neighborhood Hits	66	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UJD0, Q92511	Gene names	RIMS3, KIAA0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RIMS3_MOUSE
θ value	5.64607e-111 (rank : 5)	NC score	0.871114 (rank : 7)
Query Neighborhood Hits	376	Target Neighborhood Hits	67	Shared Neighborhood Hits	66
SwissProt Accessions	Q80U57	Gene names	Rims3, Kiaa0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RIMS4_HUMAN
θ value	6.07444e-89 (rank : 6)	NC score	0.883045 (rank : 5)
Query Neighborhood Hits	376	Target Neighborhood Hits	76	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H426, Q5JWT7	Gene names	RIMS4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

RIMS4_MOUSE
θ value	1.76739e-88 (rank : 7)	NC score	0.883349 (rank : 4)
Query Neighborhood Hits	376	Target Neighborhood Hits	76	Shared Neighborhood Hits	71
SwissProt Accessions	P60191	Gene names	Rims4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

PCLO_MOUSE
θ value	2.27234e-27 (rank : 8)	NC score	0.520817 (rank : 42)
Query Neighborhood Hits	376	Target Neighborhood Hits	2275	Shared Neighborhood Hits	264
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PCLO_HUMAN
θ value	3.17815e-21 (rank : 9)	NC score	0.493378 (rank : 49)
Query Neighborhood Hits	376	Target Neighborhood Hits	2046	Shared Neighborhood Hits	186
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

DOC2B_HUMAN
θ value	1.2105e-12 (rank : 10)	NC score	0.582756 (rank : 13)
Query Neighborhood Hits	376	Target Neighborhood Hits	150	Shared Neighborhood Hits	107
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

DOC2B_MOUSE
θ value	1.2105e-12 (rank : 11)	NC score	0.580655 (rank : 16)
Query Neighborhood Hits	376	Target Neighborhood Hits	169	Shared Neighborhood Hits	107
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

P3C2B_HUMAN
θ value	1.2105e-12 (rank : 12)	NC score	0.436756 (rank : 53)
Query Neighborhood Hits	376	Target Neighborhood Hits	148	Shared Neighborhood Hits	82
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

SYTL4_MOUSE
θ value	3.52202e-12 (rank : 13)	NC score	0.581987 (rank : 14)
Query Neighborhood Hits	376	Target Neighborhood Hits	137	Shared Neighborhood Hits	97
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

FA62A_HUMAN
θ value	4.59992e-12 (rank : 14)	NC score	0.549000 (rank : 26)
Query Neighborhood Hits	376	Target Neighborhood Hits	168	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

RP3A_HUMAN
θ value	4.59992e-12 (rank : 15)	NC score	0.581840 (rank : 15)
Query Neighborhood Hits	376	Target Neighborhood Hits	305	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SYTL4_HUMAN
θ value	6.00763e-12 (rank : 16)	NC score	0.584804 (rank : 11)
Query Neighborhood Hits	376	Target Neighborhood Hits	138	Shared Neighborhood Hits	93
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

KPCB_HUMAN
θ value	1.02475e-11 (rank : 17)	NC score	0.165415 (rank : 171)
Query Neighborhood Hits	376	Target Neighborhood Hits	1121	Shared Neighborhood Hits	114
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

RP3A_MOUSE
θ value	1.02475e-11 (rank : 18)	NC score	0.571694 (rank : 19)
Query Neighborhood Hits	376	Target Neighborhood Hits	510	Shared Neighborhood Hits	125
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SYT3_HUMAN
θ value	1.02475e-11 (rank : 19)	NC score	0.563827 (rank : 21)
Query Neighborhood Hits	376	Target Neighborhood Hits	145	Shared Neighborhood Hits	103
SwissProt Accessions	Q9BQG1, Q8N5Z1, Q8N640	Gene names	SYT3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

DOC2A_HUMAN
θ value	2.28291e-11 (rank : 20)	NC score	0.590733 (rank : 9)
Query Neighborhood Hits	376	Target Neighborhood Hits	144	Shared Neighborhood Hits	106
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

DOC2A_MOUSE
θ value	2.98157e-11 (rank : 21)	NC score	0.593071 (rank : 8)
Query Neighborhood Hits	376	Target Neighborhood Hits	140	Shared Neighborhood Hits	105
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

KPCA_HUMAN
θ value	2.98157e-11 (rank : 22)	NC score	0.169077 (rank : 163)
Query Neighborhood Hits	376	Target Neighborhood Hits	1070	Shared Neighborhood Hits	114
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

SYT9_MOUSE
θ value	2.98157e-11 (rank : 23)	NC score	0.547728 (rank : 31)
Query Neighborhood Hits	376	Target Neighborhood Hits	148	Shared Neighborhood Hits	106
SwissProt Accessions	Q9R0N9, Q8C280	Gene names	Syt9, Syt5
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V).

SYTL5_HUMAN
θ value	3.89403e-11 (rank : 24)	NC score	0.579545 (rank : 17)
Query Neighborhood Hits	376	Target Neighborhood Hits	237	Shared Neighborhood Hits	120
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

KPCB_MOUSE
θ value	6.64225e-11 (rank : 25)	NC score	0.166346 (rank : 168)
Query Neighborhood Hits	376	Target Neighborhood Hits	1117	Shared Neighborhood Hits	113
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

SYT6_MOUSE
θ value	8.67504e-11 (rank : 26)	NC score	0.549016 (rank : 25)
Query Neighborhood Hits	376	Target Neighborhood Hits	132	Shared Neighborhood Hits	105
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT6_HUMAN
θ value	1.47974e-10 (rank : 27)	NC score	0.548010 (rank : 30)
Query Neighborhood Hits	376	Target Neighborhood Hits	138	Shared Neighborhood Hits	108
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

KPCA_MOUSE
θ value	2.52405e-10 (rank : 28)	NC score	0.164700 (rank : 172)
Query Neighborhood Hits	376	Target Neighborhood Hits	1067	Shared Neighborhood Hits	114
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

SYT10_HUMAN
θ value	2.52405e-10 (rank : 29)	NC score	0.543164 (rank : 34)
Query Neighborhood Hits	376	Target Neighborhood Hits	134	Shared Neighborhood Hits	105
SwissProt Accessions	Q6XYQ8	Gene names	SYT10
Domain Architecture	No domain graphic available
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT3_MOUSE
θ value	2.52405e-10 (rank : 30)	NC score	0.559361 (rank : 23)
Query Neighborhood Hits	376	Target Neighborhood Hits	147	Shared Neighborhood Hits	102
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

KPCG_MOUSE
θ value	4.30538e-10 (rank : 31)	NC score	0.179682 (rank : 149)
Query Neighborhood Hits	376	Target Neighborhood Hits	1123	Shared Neighborhood Hits	112
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

SYT9_HUMAN
θ value	4.30538e-10 (rank : 32)	NC score	0.544775 (rank : 33)
Query Neighborhood Hits	376	Target Neighborhood Hits	144	Shared Neighborhood Hits	105
SwissProt Accessions	Q86SS6	Gene names	SYT9
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX).

SYT2_MOUSE
θ value	5.62301e-10 (rank : 33)	NC score	0.548400 (rank : 28)
Query Neighborhood Hits	376	Target Neighborhood Hits	143	Shared Neighborhood Hits	106
SwissProt Accessions	P46097, Q8R0E1	Gene names	Syt2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

KPCG_HUMAN
θ value	7.34386e-10 (rank : 34)	NC score	0.178712 (rank : 151)
Query Neighborhood Hits	376	Target Neighborhood Hits	1126	Shared Neighborhood Hits	112
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

SYT10_MOUSE
θ value	7.34386e-10 (rank : 35)	NC score	0.541167 (rank : 35)
Query Neighborhood Hits	376	Target Neighborhood Hits	133	Shared Neighborhood Hits	106
SwissProt Accessions	Q9R0N4	Gene names	Syt10
Domain Architecture
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT2_HUMAN
θ value	7.34386e-10 (rank : 36)	NC score	0.548052 (rank : 29)
Query Neighborhood Hits	376	Target Neighborhood Hits	142	Shared Neighborhood Hits	106
SwissProt Accessions	Q8N9I0, Q496K5, Q8NBE5	Gene names	SYT2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT7_MOUSE
θ value	1.25267e-09 (rank : 37)	NC score	0.572672 (rank : 18)
Query Neighborhood Hits	376	Target Neighborhood Hits	137	Shared Neighborhood Hits	105
SwissProt Accessions	Q9R0N7	Gene names	Syt7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

SYTL1_HUMAN
θ value	1.25267e-09 (rank : 38)	NC score	0.583807 (rank : 12)
Query Neighborhood Hits	376	Target Neighborhood Hits	227	Shared Neighborhood Hits	105
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

SYTL3_MOUSE
θ value	2.79066e-09 (rank : 39)	NC score	0.587927 (rank : 10)
Query Neighborhood Hits	376	Target Neighborhood Hits	110	Shared Neighborhood Hits	83
SwissProt Accessions	Q99N48, Q8C506, Q99N47, Q99N49, Q99N54, Q99N79	Gene names	Sytl3, Slp3
Domain Architecture
Description	Synaptotagmin-like protein 3 (Exophilin-6).

SYT1_HUMAN
θ value	6.21693e-09 (rank : 40)	NC score	0.538454 (rank : 37)
Query Neighborhood Hits	376	Target Neighborhood Hits	150	Shared Neighborhood Hits	105
SwissProt Accessions	P21579	Gene names	SYT1, SYT
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT1_MOUSE
θ value	6.21693e-09 (rank : 41)	NC score	0.538442 (rank : 38)
Query Neighborhood Hits	376	Target Neighborhood Hits	150	Shared Neighborhood Hits	105
SwissProt Accessions	P46096	Gene names	Syt1
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

FA62A_MOUSE
θ value	1.06045e-08 (rank : 42)	NC score	0.548769 (rank : 27)
Query Neighborhood Hits	376	Target Neighborhood Hits	155	Shared Neighborhood Hits	107
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

SYTL1_MOUSE
θ value	1.06045e-08 (rank : 43)	NC score	0.553780 (rank : 24)
Query Neighborhood Hits	376	Target Neighborhood Hits	314	Shared Neighborhood Hits	99
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

P3C2A_HUMAN
θ value	3.08544e-08 (rank : 44)	NC score	0.381292 (rank : 55)
Query Neighborhood Hits	376	Target Neighborhood Hits	188	Shared Neighborhood Hits	75
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

SYT7_HUMAN
θ value	5.26297e-08 (rank : 45)	NC score	0.559821 (rank : 22)
Query Neighborhood Hits	376	Target Neighborhood Hits	137	Shared Neighborhood Hits	105
SwissProt Accessions	O43581	Gene names	SYT7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

P3C2A_MOUSE
θ value	6.87365e-08 (rank : 46)	NC score	0.376674 (rank : 56)
Query Neighborhood Hits	376	Target Neighborhood Hits	181	Shared Neighborhood Hits	75
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

PTN13_HUMAN
θ value	2.61198e-07 (rank : 47)	NC score	0.156842 (rank : 176)
Query Neighborhood Hits	376	Target Neighborhood Hits	471	Shared Neighborhood Hits	127
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

SYTL2_MOUSE
θ value	4.45536e-07 (rank : 48)	NC score	0.540532 (rank : 36)
Query Neighborhood Hits	376	Target Neighborhood Hits	253	Shared Neighborhood Hits	111
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYT5_HUMAN
θ value	5.81887e-07 (rank : 49)	NC score	0.530103 (rank : 40)
Query Neighborhood Hits	376	Target Neighborhood Hits	138	Shared Neighborhood Hits	107
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

SYTL2_HUMAN
θ value	5.81887e-07 (rank : 50)	NC score	0.544893 (rank : 32)
Query Neighborhood Hits	376	Target Neighborhood Hits	248	Shared Neighborhood Hits	110
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

RASL2_HUMAN
θ value	7.59969e-07 (rank : 51)	NC score	0.432253 (rank : 54)
Query Neighborhood Hits	376	Target Neighborhood Hits	161	Shared Neighborhood Hits	97
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

SYTL5_MOUSE
θ value	9.92553e-07 (rank : 52)	NC score	0.568276 (rank : 20)
Query Neighborhood Hits	376	Target Neighborhood Hits	154	Shared Neighborhood Hits	101
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SYT4_HUMAN
θ value	1.69304e-06 (rank : 53)	NC score	0.518831 (rank : 43)
Query Neighborhood Hits	376	Target Neighborhood Hits	121	Shared Neighborhood Hits	100
SwissProt Accessions	Q9H2B2, Q9P2K4	Gene names	SYT4, KIAA1342
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

PTN13_MOUSE
θ value	2.21117e-06 (rank : 54)	NC score	0.149683 (rank : 180)
Query Neighborhood Hits	376	Target Neighborhood Hits	426	Shared Neighborhood Hits	114
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

RGS3_HUMAN
θ value	2.88788e-06 (rank : 55)	NC score	0.211980 (rank : 104)
Query Neighborhood Hits	376	Target Neighborhood Hits	1375	Shared Neighborhood Hits	145
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SYT11_MOUSE
θ value	2.88788e-06 (rank : 56)	NC score	0.512379 (rank : 45)
Query Neighborhood Hits	376	Target Neighborhood Hits	116	Shared Neighborhood Hits	98
SwissProt Accessions	Q9R0N3	Gene names	Syt11
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

UN13B_HUMAN
θ value	2.88788e-06 (rank : 57)	NC score	0.318675 (rank : 65)
Query Neighborhood Hits	376	Target Neighborhood Hits	217	Shared Neighborhood Hits	96
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

SYT11_HUMAN
θ value	3.77169e-06 (rank : 58)	NC score	0.511162 (rank : 46)
Query Neighborhood Hits	376	Target Neighborhood Hits	113	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BT88, Q14998, Q68CT5, Q8IXU3, Q96SU2	Gene names	SYT11, KIAA0080
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

UN13B_MOUSE
θ value	3.77169e-06 (rank : 59)	NC score	0.320046 (rank : 64)
Query Neighborhood Hits	376	Target Neighborhood Hits	210	Shared Neighborhood Hits	90
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

SYT4_MOUSE
θ value	4.92598e-06 (rank : 60)	NC score	0.512523 (rank : 44)
Query Neighborhood Hits	376	Target Neighborhood Hits	123	Shared Neighborhood Hits	98
SwissProt Accessions	P40749, Q3UFC1, Q8BGH3, Q8BRL6	Gene names	Syt4, Syt3
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

DOC2G_MOUSE
θ value	8.40245e-06 (rank : 61)	NC score	0.537926 (rank : 39)
Query Neighborhood Hits	376	Target Neighborhood Hits	125	Shared Neighborhood Hits	94
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

UN13A_HUMAN
θ value	8.40245e-06 (rank : 62)	NC score	0.317916 (rank : 66)
Query Neighborhood Hits	376	Target Neighborhood Hits	285	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

MPDZ_HUMAN
θ value	1.43324e-05 (rank : 63)	NC score	0.243629 (rank : 78)
Query Neighborhood Hits	376	Target Neighborhood Hits	261	Shared Neighborhood Hits	105
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

PDZD2_HUMAN
θ value	1.43324e-05 (rank : 64)	NC score	0.255926 (rank : 75)
Query Neighborhood Hits	376	Target Neighborhood Hits	772	Shared Neighborhood Hits	135
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

SYT15_HUMAN
θ value	1.87187e-05 (rank : 65)	NC score	0.487316 (rank : 50)
Query Neighborhood Hits	376	Target Neighborhood Hits	112	Shared Neighborhood Hits	91
SwissProt Accessions	Q9BQS2, Q7Z439, Q7Z440	Gene names	SYT15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV) (Chr10Syt).

SYT5_MOUSE
θ value	4.1701e-05 (rank : 66)	NC score	0.523122 (rank : 41)
Query Neighborhood Hits	376	Target Neighborhood Hits	140	Shared Neighborhood Hits	107
SwissProt Accessions	Q9R0N5	Gene names	Syt5, Syt9
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin IX).

MPDZ_MOUSE
θ value	5.44631e-05 (rank : 67)	NC score	0.241684 (rank : 81)
Query Neighborhood Hits	376	Target Neighborhood Hits	298	Shared Neighborhood Hits	108
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

IL16_HUMAN
θ value	7.1131e-05 (rank : 68)	NC score	0.248176 (rank : 76)
Query Neighborhood Hits	376	Target Neighborhood Hits	207	Shared Neighborhood Hits	93
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

NIPBL_HUMAN
θ value	7.1131e-05 (rank : 69)	NC score	0.123666 (rank : 210)
Query Neighborhood Hits	376	Target Neighborhood Hits	1311	Shared Neighborhood Hits	129
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

MYRIP_MOUSE
θ value	9.29e-05 (rank : 70)	NC score	0.179902 (rank : 148)
Query Neighborhood Hits	376	Target Neighborhood Hits	207	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

ZO3_MOUSE
θ value	9.29e-05 (rank : 71)	NC score	0.203792 (rank : 110)
Query Neighborhood Hits	376	Target Neighborhood Hits	224	Shared Neighborhood Hits	101
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

P3C2G_HUMAN
θ value	0.000158464 (rank : 72)	NC score	0.204938 (rank : 108)
Query Neighborhood Hits	376	Target Neighborhood Hits	92	Shared Neighborhood Hits	48
SwissProt Accessions	O75747	Gene names	PIK3C2G
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

SYT12_HUMAN
θ value	0.000158464 (rank : 73)	NC score	0.506828 (rank : 47)
Query Neighborhood Hits	376	Target Neighborhood Hits	100	Shared Neighborhood Hits	80
SwissProt Accessions	Q8IV01	Gene names	SYT12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

NED4L_HUMAN
θ value	0.00020696 (rank : 74)	NC score	0.283437 (rank : 69)
Query Neighborhood Hits	376	Target Neighborhood Hits	238	Shared Neighborhood Hits	114
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_MOUSE
θ value	0.00020696 (rank : 75)	NC score	0.278722 (rank : 70)
Query Neighborhood Hits	376	Target Neighborhood Hits	231	Shared Neighborhood Hits	113
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

SRRM2_MOUSE
θ value	0.00020696 (rank : 76)	NC score	0.136014 (rank : 192)
Query Neighborhood Hits	376	Target Neighborhood Hits	1470	Shared Neighborhood Hits	110
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

USH1C_HUMAN
θ value	0.000270298 (rank : 77)	NC score	0.236171 (rank : 83)
Query Neighborhood Hits	376	Target Neighborhood Hits	327	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

USH1C_MOUSE
θ value	0.000270298 (rank : 78)	NC score	0.227272 (rank : 93)
Query Neighborhood Hits	376	Target Neighborhood Hits	557	Shared Neighborhood Hits	126
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

INADL_HUMAN
θ value	0.00035302 (rank : 79)	NC score	0.235114 (rank : 84)
Query Neighborhood Hits	376	Target Neighborhood Hits	260	Shared Neighborhood Hits	103
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

INADL_MOUSE
θ value	0.00035302 (rank : 80)	NC score	0.234865 (rank : 85)
Query Neighborhood Hits	376	Target Neighborhood Hits	290	Shared Neighborhood Hits	106
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

P3C2G_MOUSE
θ value	0.000461057 (rank : 81)	NC score	0.228661 (rank : 90)
Query Neighborhood Hits	376	Target Neighborhood Hits	113	Shared Neighborhood Hits	65
SwissProt Accessions	O70167, O70168	Gene names	Pik3c2g
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

SRRM2_HUMAN
θ value	0.000461057 (rank : 82)	NC score	0.121331 (rank : 212)
Query Neighborhood Hits	376	Target Neighborhood Hits	1296	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SYT12_MOUSE
θ value	0.000461057 (rank : 83)	NC score	0.506307 (rank : 48)
Query Neighborhood Hits	376	Target Neighborhood Hits	102	Shared Neighborhood Hits	83
SwissProt Accessions	Q920N7	Gene names	Syt12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

TRHY_HUMAN
θ value	0.000461057 (rank : 84)	NC score	0.044103 (rank : 382)
Query Neighborhood Hits	376	Target Neighborhood Hits	1385	Shared Neighborhood Hits	85
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

RASL1_HUMAN
θ value	0.00102713 (rank : 85)	NC score	0.336792 (rank : 62)
Query Neighborhood Hits	376	Target Neighborhood Hits	142	Shared Neighborhood Hits	86
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

WHRN_MOUSE
θ value	0.00134147 (rank : 86)	NC score	0.219333 (rank : 97)
Query Neighborhood Hits	376	Target Neighborhood Hits	412	Shared Neighborhood Hits	116
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

IL16_MOUSE
θ value	0.00175202 (rank : 87)	NC score	0.237412 (rank : 82)
Query Neighborhood Hits	376	Target Neighborhood Hits	189	Shared Neighborhood Hits	94
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

STXB4_HUMAN
θ value	0.00175202 (rank : 88)	NC score	0.171008 (rank : 157)
Query Neighborhood Hits	376	Target Neighborhood Hits	616	Shared Neighborhood Hits	112
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

SFR12_HUMAN
θ value	0.00228821 (rank : 89)	NC score	0.088233 (rank : 268)
Query Neighborhood Hits	376	Target Neighborhood Hits	553	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

STXB4_MOUSE
θ value	0.00228821 (rank : 90)	NC score	0.170744 (rank : 159)
Query Neighborhood Hits	376	Target Neighborhood Hits	629	Shared Neighborhood Hits	112
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

LIN7B_HUMAN
θ value	0.00298849 (rank : 91)	NC score	0.217505 (rank : 98)
Query Neighborhood Hits	376	Target Neighborhood Hits	200	Shared Neighborhood Hits	100
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

LNX2_HUMAN
θ value	0.00298849 (rank : 92)	NC score	0.205865 (rank : 107)
Query Neighborhood Hits	376	Target Neighborhood Hits	389	Shared Neighborhood Hits	102
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

NEDD4_HUMAN
θ value	0.00298849 (rank : 93)	NC score	0.259694 (rank : 74)
Query Neighborhood Hits	376	Target Neighborhood Hits	214	Shared Neighborhood Hits	114
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

RASL1_MOUSE
θ value	0.00298849 (rank : 94)	NC score	0.323008 (rank : 63)
Query Neighborhood Hits	376	Target Neighborhood Hits	148	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

SFR11_HUMAN
θ value	0.00298849 (rank : 95)	NC score	0.110836 (rank : 235)
Query Neighborhood Hits	376	Target Neighborhood Hits	246	Shared Neighborhood Hits	40
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

DLG2_HUMAN
θ value	0.00390308 (rank : 96)	NC score	0.194567 (rank : 119)
Query Neighborhood Hits	376	Target Neighborhood Hits	279	Shared Neighborhood Hits	104
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG5_HUMAN
θ value	0.00390308 (rank : 97)	NC score	0.148229 (rank : 183)
Query Neighborhood Hits	376	Target Neighborhood Hits	1088	Shared Neighborhood Hits	145
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

LIN7B_MOUSE
θ value	0.00390308 (rank : 98)	NC score	0.216671 (rank : 99)
Query Neighborhood Hits	376	Target Neighborhood Hits	200	Shared Neighborhood Hits	100
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

PA24B_HUMAN
θ value	0.00390308 (rank : 99)	NC score	0.209546 (rank : 105)
Query Neighborhood Hits	376	Target Neighborhood Hits	89	Shared Neighborhood Hits	68
SwissProt Accessions	O95712, Q59GF9, Q8TB10, Q9UKV7	Gene names	PLA2G4B
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

PAR6G_MOUSE
θ value	0.00509761 (rank : 100)	NC score	0.184266 (rank : 138)
Query Neighborhood Hits	376	Target Neighborhood Hits	121	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

SFR12_MOUSE
θ value	0.00509761 (rank : 101)	NC score	0.099776 (rank : 248)
Query Neighborhood Hits	376	Target Neighborhood Hits	486	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

UN13D_HUMAN
θ value	0.00509761 (rank : 102)	NC score	0.361029 (rank : 57)
Query Neighborhood Hits	376	Target Neighborhood Hits	117	Shared Neighborhood Hits	86
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

DLG2_MOUSE
θ value	0.00665767 (rank : 103)	NC score	0.195465 (rank : 116)
Query Neighborhood Hits	376	Target Neighborhood Hits	271	Shared Neighborhood Hits	104
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

PAR3L_HUMAN
θ value	0.00869519 (rank : 104)	NC score	0.226313 (rank : 94)
Query Neighborhood Hits	376	Target Neighborhood Hits	297	Shared Neighborhood Hits	105
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

PARD3_MOUSE
θ value	0.00869519 (rank : 105)	NC score	0.227800 (rank : 92)
Query Neighborhood Hits	376	Target Neighborhood Hits	290	Shared Neighborhood Hits	126
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

ZC313_HUMAN
θ value	0.00869519 (rank : 106)	NC score	0.081136 (rank : 284)
Query Neighborhood Hits	376	Target Neighborhood Hits	772	Shared Neighborhood Hits	91
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

ZO3_HUMAN
θ value	0.00869519 (rank : 107)	NC score	0.183413 (rank : 141)
Query Neighborhood Hits	376	Target Neighborhood Hits	219	Shared Neighborhood Hits	96
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

LNX1_MOUSE
θ value	0.0113563 (rank : 108)	NC score	0.202231 (rank : 111)
Query Neighborhood Hits	376	Target Neighborhood Hits	377	Shared Neighborhood Hits	106
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

PAR6A_HUMAN
θ value	0.0113563 (rank : 109)	NC score	0.180456 (rank : 144)
Query Neighborhood Hits	376	Target Neighborhood Hits	119	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

PARD3_HUMAN
θ value	0.0113563 (rank : 110)	NC score	0.229245 (rank : 89)
Query Neighborhood Hits	376	Target Neighborhood Hits	312	Shared Neighborhood Hits	127
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

SNTA1_HUMAN
θ value	0.0113563 (rank : 111)	NC score	0.200558 (rank : 113)
Query Neighborhood Hits	376	Target Neighborhood Hits	186	Shared Neighborhood Hits	94
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

WHRN_HUMAN
θ value	0.0113563 (rank : 112)	NC score	0.214324 (rank : 100)
Query Neighborhood Hits	376	Target Neighborhood Hits	325	Shared Neighborhood Hits	107
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

LIN7C_HUMAN
θ value	0.0148317 (rank : 113)	NC score	0.212437 (rank : 102)
Query Neighborhood Hits	376	Target Neighborhood Hits	198	Shared Neighborhood Hits	100
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
θ value	0.0148317 (rank : 114)	NC score	0.212437 (rank : 103)
Query Neighborhood Hits	376	Target Neighborhood Hits	198	Shared Neighborhood Hits	100
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LNX2_MOUSE
θ value	0.0148317 (rank : 115)	NC score	0.204557 (rank : 109)
Query Neighborhood Hits	376	Target Neighborhood Hits	407	Shared Neighborhood Hits	103
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

PA24D_MOUSE
θ value	0.0148317 (rank : 116)	NC score	0.275855 (rank : 71)
Query Neighborhood Hits	376	Target Neighborhood Hits	100	Shared Neighborhood Hits	82
SwissProt Accessions	Q50L43, Q3TJC5	Gene names	Pla2g4d
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

PAR6A_MOUSE
θ value	0.0148317 (rank : 117)	NC score	0.179991 (rank : 146)
Query Neighborhood Hits	376	Target Neighborhood Hits	115	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

RSRC1_HUMAN
θ value	0.0148317 (rank : 118)	NC score	0.113745 (rank : 226)
Query Neighborhood Hits	376	Target Neighborhood Hits	108	Shared Neighborhood Hits	20
SwissProt Accessions	Q96IZ7, Q96QK2, Q9NZE5	Gene names	RSRC1
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich coiled coil protein 1.

SYT8_MOUSE
θ value	0.0148317 (rank : 119)	NC score	0.472101 (rank : 51)
Query Neighborhood Hits	376	Target Neighborhood Hits	94	Shared Neighborhood Hits	78
SwissProt Accessions	Q9R0N6, Q64366, Q8C6E7	Gene names	Syt8
Domain Architecture
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

GP143_HUMAN
θ value	0.0193708 (rank : 120)	NC score	0.087273 (rank : 270)
Query Neighborhood Hits	376	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	P51810	Gene names	GPR143, OA1
Domain Architecture
Description	G-protein coupled receptor 143 (Ocular albinism type 1 protein).

NEDD4_MOUSE
θ value	0.0193708 (rank : 121)	NC score	0.244804 (rank : 77)
Query Neighborhood Hits	376	Target Neighborhood Hits	212	Shared Neighborhood Hits	113
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

DLG4_HUMAN
θ value	0.0252991 (rank : 122)	NC score	0.191600 (rank : 123)
Query Neighborhood Hits	376	Target Neighborhood Hits	286	Shared Neighborhood Hits	99
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_MOUSE
θ value	0.0252991 (rank : 123)	NC score	0.191968 (rank : 121)
Query Neighborhood Hits	376	Target Neighborhood Hits	282	Shared Neighborhood Hits	100
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

HGS_MOUSE
θ value	0.0252991 (rank : 124)	NC score	0.043528 (rank : 384)
Query Neighborhood Hits	376	Target Neighborhood Hits	589	Shared Neighborhood Hits	42
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

PRP4B_HUMAN
θ value	0.0252991 (rank : 125)	NC score	0.029763 (rank : 414)
Query Neighborhood Hits	376	Target Neighborhood Hits	1030	Shared Neighborhood Hits	54
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

RN168_HUMAN
θ value	0.0252991 (rank : 126)	NC score	0.056177 (rank : 347)
Query Neighborhood Hits	376	Target Neighborhood Hits	370	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

SMUF1_HUMAN
θ value	0.0252991 (rank : 127)	NC score	0.138309 (rank : 188)
Query Neighborhood Hits	376	Target Neighborhood Hits	135	Shared Neighborhood Hits	67
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

SMUF1_MOUSE
θ value	0.0252991 (rank : 128)	NC score	0.137417 (rank : 191)
Query Neighborhood Hits	376	Target Neighborhood Hits	142	Shared Neighborhood Hits	67
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

SMUF2_HUMAN
θ value	0.0252991 (rank : 129)	NC score	0.137905 (rank : 190)
Query Neighborhood Hits	376	Target Neighborhood Hits	142	Shared Neighborhood Hits	70
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

CK5P2_HUMAN
θ value	0.0330416 (rank : 130)	NC score	0.044513 (rank : 381)
Query Neighborhood Hits	376	Target Neighborhood Hits	1433	Shared Neighborhood Hits	96
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

GPTC8_HUMAN
θ value	0.0330416 (rank : 131)	NC score	0.105207 (rank : 241)
Query Neighborhood Hits	376	Target Neighborhood Hits	366	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

PAR6G_HUMAN
θ value	0.0330416 (rank : 132)	NC score	0.178908 (rank : 150)
Query Neighborhood Hits	376	Target Neighborhood Hits	159	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

SRRM1_HUMAN
θ value	0.0330416 (rank : 133)	NC score	0.095169 (rank : 253)
Query Neighborhood Hits	376	Target Neighborhood Hits	690	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

LAP4_HUMAN
θ value	0.0431538 (rank : 134)	NC score	0.128566 (rank : 201)
Query Neighborhood Hits	376	Target Neighborhood Hits	608	Shared Neighborhood Hits	116
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

MPP5_HUMAN
θ value	0.0431538 (rank : 135)	NC score	0.140439 (rank : 185)
Query Neighborhood Hits	376	Target Neighborhood Hits	231	Shared Neighborhood Hits	99
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
θ value	0.0431538 (rank : 136)	NC score	0.139977 (rank : 186)
Query Neighborhood Hits	376	Target Neighborhood Hits	226	Shared Neighborhood Hits	97
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

SNTB1_HUMAN
θ value	0.0431538 (rank : 137)	NC score	0.178674 (rank : 152)
Query Neighborhood Hits	376	Target Neighborhood Hits	157	Shared Neighborhood Hits	87
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
θ value	0.0431538 (rank : 138)	NC score	0.183606 (rank : 140)
Query Neighborhood Hits	376	Target Neighborhood Hits	160	Shared Neighborhood Hits	87
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

SNTG2_HUMAN
θ value	0.0431538 (rank : 139)	NC score	0.195275 (rank : 117)
Query Neighborhood Hits	376	Target Neighborhood Hits	191	Shared Neighborhood Hits	99
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

K1849_MOUSE
θ value	0.0563607 (rank : 140)	NC score	0.170983 (rank : 158)
Query Neighborhood Hits	376	Target Neighborhood Hits	335	Shared Neighborhood Hits	99
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

PA24B_MOUSE
θ value	0.0563607 (rank : 141)	NC score	0.230393 (rank : 88)
Query Neighborhood Hits	376	Target Neighborhood Hits	102	Shared Neighborhood Hits	77
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

SNTA1_MOUSE
θ value	0.0563607 (rank : 142)	NC score	0.186583 (rank : 132)
Query Neighborhood Hits	376	Target Neighborhood Hits	170	Shared Neighborhood Hits	91
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

BCLF1_HUMAN
θ value	0.0736092 (rank : 143)	NC score	0.066521 (rank : 311)
Query Neighborhood Hits	376	Target Neighborhood Hits	298	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NYF8, Q14673, Q86WU6, Q86WY0	Gene names	BCLAF1, BTF, KIAA0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

BCLF1_MOUSE
θ value	0.0736092 (rank : 144)	NC score	0.062068 (rank : 327)
Query Neighborhood Hits	376	Target Neighborhood Hits	303	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K019, Q8BNZ0, Q8C2E9, Q9CSW5	Gene names	Bclaf1, Btf, Kiaa0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

CCD41_MOUSE
θ value	0.0736092 (rank : 145)	NC score	0.035522 (rank : 399)
Query Neighborhood Hits	376	Target Neighborhood Hits	1399	Shared Neighborhood Hits	79
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

ITSN1_HUMAN
θ value	0.0736092 (rank : 146)	NC score	0.115295 (rank : 222)
Query Neighborhood Hits	376	Target Neighborhood Hits	1757	Shared Neighborhood Hits	170
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

MAGI1_HUMAN
θ value	0.0736092 (rank : 147)	NC score	0.196476 (rank : 115)
Query Neighborhood Hits	376	Target Neighborhood Hits	388	Shared Neighborhood Hits	141
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

ATRX_MOUSE
θ value	0.0961366 (rank : 148)	NC score	0.049966 (rank : 372)
Query Neighborhood Hits	376	Target Neighborhood Hits	682	Shared Neighborhood Hits	62
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

CROP_HUMAN
θ value	0.0961366 (rank : 149)	NC score	0.062280 (rank : 326)
Query Neighborhood Hits	376	Target Neighborhood Hits	402	Shared Neighborhood Hits	49
SwissProt Accessions	O95232, Q6PHR9, Q9NUY0, Q9P2S7	Gene names	CROP, CREAP1, O48
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18).

GIPC1_MOUSE
θ value	0.0961366 (rank : 150)	NC score	0.122450 (rank : 211)
Query Neighborhood Hits	376	Target Neighborhood Hits	92	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

LAP4_MOUSE
θ value	0.0961366 (rank : 151)	NC score	0.127291 (rank : 204)
Query Neighborhood Hits	376	Target Neighborhood Hits	590	Shared Neighborhood Hits	112
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

MYRIP_HUMAN
θ value	0.0961366 (rank : 152)	NC score	0.153161 (rank : 178)
Query Neighborhood Hits	376	Target Neighborhood Hits	269	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

SYT15_MOUSE
θ value	0.0961366 (rank : 153)	NC score	0.448014 (rank : 52)
Query Neighborhood Hits	376	Target Neighborhood Hits	100	Shared Neighborhood Hits	87
SwissProt Accessions	Q8C6N3, Q7TN81, Q7TN82, Q8C999	Gene names	Syt15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV).

GIPC1_HUMAN
θ value	0.125558 (rank : 154)	NC score	0.118938 (rank : 214)
Query Neighborhood Hits	376	Target Neighborhood Hits	91	Shared Neighborhood Hits	62
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

NPBL_MOUSE
θ value	0.125558 (rank : 155)	NC score	0.116673 (rank : 218)
Query Neighborhood Hits	376	Target Neighborhood Hits	1041	Shared Neighborhood Hits	111
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PA24F_MOUSE
θ value	0.125558 (rank : 156)	NC score	0.170338 (rank : 160)
Query Neighborhood Hits	376	Target Neighborhood Hits	93	Shared Neighborhood Hits	69
SwissProt Accessions	Q50L41, Q80VQ8, Q80VV9	Gene names	Pla2g4f
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

PICK1_HUMAN
θ value	0.125558 (rank : 157)	NC score	0.172792 (rank : 156)
Query Neighborhood Hits	376	Target Neighborhood Hits	132	Shared Neighborhood Hits	94
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

RSRC1_MOUSE
θ value	0.125558 (rank : 158)	NC score	0.088758 (rank : 267)
Query Neighborhood Hits	376	Target Neighborhood Hits	93	Shared Neighborhood Hits	21
SwissProt Accessions	Q9DBU6, Q3TF06	Gene names	Rsrc1
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich coiled coil protein 1.

SFRS4_HUMAN
θ value	0.125558 (rank : 159)	NC score	0.056541 (rank : 344)
Query Neighborhood Hits	376	Target Neighborhood Hits	384	Shared Neighborhood Hits	37
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

SNTB2_HUMAN
θ value	0.125558 (rank : 160)	NC score	0.186837 (rank : 131)
Query Neighborhood Hits	376	Target Neighborhood Hits	180	Shared Neighborhood Hits	92
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTB2_MOUSE
θ value	0.125558 (rank : 161)	NC score	0.186163 (rank : 133)
Query Neighborhood Hits	376	Target Neighborhood Hits	181	Shared Neighborhood Hits	92
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

AFAD_HUMAN
θ value	0.163984 (rank : 162)	NC score	0.160674 (rank : 174)
Query Neighborhood Hits	376	Target Neighborhood Hits	689	Shared Neighborhood Hits	134
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

FA47A_HUMAN
θ value	0.163984 (rank : 163)	NC score	0.086299 (rank : 272)
Query Neighborhood Hits	376	Target Neighborhood Hits	451	Shared Neighborhood Hits	34
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

HIP1_HUMAN
θ value	0.163984 (rank : 164)	NC score	0.035077 (rank : 401)
Query Neighborhood Hits	376	Target Neighborhood Hits	1016	Shared Neighborhood Hits	63
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

IBRD1_HUMAN
θ value	0.163984 (rank : 165)	NC score	0.063113 (rank : 322)
Query Neighborhood Hits	376	Target Neighborhood Hits	62	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TC41, Q9BX48	Gene names	IBRDC1
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 1.

ITSN2_HUMAN
θ value	0.163984 (rank : 166)	NC score	0.138267 (rank : 189)
Query Neighborhood Hits	376	Target Neighborhood Hits	1173	Shared Neighborhood Hits	135
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

LC7L2_HUMAN
θ value	0.163984 (rank : 167)	NC score	0.063176 (rank : 321)
Query Neighborhood Hits	376	Target Neighborhood Hits	235	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y383, Q8IUP9, Q9NVL3, Q9NVN7, Q9UQN1	Gene names	LUC7L2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2.

PA24E_MOUSE
θ value	0.163984 (rank : 168)	NC score	0.207166 (rank : 106)
Query Neighborhood Hits	376	Target Neighborhood Hits	95	Shared Neighborhood Hits	77
SwissProt Accessions	Q50L42, Q8BX44	Gene names	Pla2g4e
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

SAFB2_HUMAN
θ value	0.163984 (rank : 169)	NC score	0.029195 (rank : 418)
Query Neighborhood Hits	376	Target Neighborhood Hits	720	Shared Neighborhood Hits	46
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

SDCG1_MOUSE
θ value	0.163984 (rank : 170)	NC score	0.037241 (rank : 397)
Query Neighborhood Hits	376	Target Neighborhood Hits	168	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CCP0, Q66JX6, Q8C9R6, Q8CA65, Q8JZT9, Q8R072, Q9CW30, Q9CYB8, Q9D4A9	Gene names	Sdccag1
Domain Architecture
Description	Serologically defined colon cancer antigen 1.

SNTG2_MOUSE
θ value	0.163984 (rank : 171)	NC score	0.181501 (rank : 142)
Query Neighborhood Hits	376	Target Neighborhood Hits	176	Shared Neighborhood Hits	94
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

SON_HUMAN
θ value	0.163984 (rank : 172)	NC score	0.049313 (rank : 374)
Query Neighborhood Hits	376	Target Neighborhood Hits	1568	Shared Neighborhood Hits	73
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

ZO1_HUMAN
θ value	0.163984 (rank : 173)	NC score	0.166854 (rank : 166)
Query Neighborhood Hits	376	Target Neighborhood Hits	474	Shared Neighborhood Hits	107
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO2_HUMAN
θ value	0.163984 (rank : 174)	NC score	0.167641 (rank : 165)
Query Neighborhood Hits	376	Target Neighborhood Hits	289	Shared Neighborhood Hits	108
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

DLG1_MOUSE
θ value	0.21417 (rank : 175)	NC score	0.184368 (rank : 137)
Query Neighborhood Hits	376	Target Neighborhood Hits	285	Shared Neighborhood Hits	102
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

GRIP1_HUMAN
θ value	0.21417 (rank : 176)	NC score	0.191807 (rank : 122)
Query Neighborhood Hits	376	Target Neighborhood Hits	231	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

ITCH_HUMAN
θ value	0.21417 (rank : 177)	NC score	0.076534 (rank : 291)
Query Neighborhood Hits	376	Target Neighborhood Hits	162	Shared Neighborhood Hits	37
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

K0408_HUMAN
θ value	0.21417 (rank : 178)	NC score	0.050368 (rank : 370)
Query Neighborhood Hits	376	Target Neighborhood Hits	101	Shared Neighborhood Hits	14
SwissProt Accessions	Q6ZU52, O43158, Q5TF20, Q7L2M2	Gene names	KIAA0408
Domain Architecture	No domain graphic available
Description	Protein KIAA0408.

LC7L2_MOUSE
θ value	0.21417 (rank : 179)	NC score	0.063552 (rank : 319)
Query Neighborhood Hits	376	Target Neighborhood Hits	244	Shared Neighborhood Hits	33
SwissProt Accessions	Q7TNC4, Q99LM5, Q99PC3	Gene names	Luc7l2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2 (CGI-74 homolog).

MYST3_HUMAN
θ value	0.21417 (rank : 180)	NC score	0.049210 (rank : 375)
Query Neighborhood Hits	376	Target Neighborhood Hits	772	Shared Neighborhood Hits	58
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MYST3_MOUSE
θ value	0.21417 (rank : 181)	NC score	0.048642 (rank : 377)
Query Neighborhood Hits	376	Target Neighborhood Hits	688	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

PRP40_MOUSE
θ value	0.21417 (rank : 182)	NC score	0.068509 (rank : 308)
Query Neighborhood Hits	376	Target Neighborhood Hits	447	Shared Neighborhood Hits	57
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

RPTN_MOUSE
θ value	0.21417 (rank : 183)	NC score	0.054438 (rank : 353)
Query Neighborhood Hits	376	Target Neighborhood Hits	650	Shared Neighborhood Hits	81
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

SRRM1_MOUSE
θ value	0.21417 (rank : 184)	NC score	0.104551 (rank : 243)
Query Neighborhood Hits	376	Target Neighborhood Hits	966	Shared Neighborhood Hits	85
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

DLG1_HUMAN
θ value	0.279714 (rank : 185)	NC score	0.184095 (rank : 139)
Query Neighborhood Hits	376	Target Neighborhood Hits	290	Shared Neighborhood Hits	103
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

HAP1_MOUSE
θ value	0.279714 (rank : 186)	NC score	0.030422 (rank : 412)
Query Neighborhood Hits	376	Target Neighborhood Hits	388	Shared Neighborhood Hits	28
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

ITSN1_MOUSE
θ value	0.279714 (rank : 187)	NC score	0.115695 (rank : 221)
Query Neighborhood Hits	376	Target Neighborhood Hits	1669	Shared Neighborhood Hits	177
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

PICK1_MOUSE
θ value	0.279714 (rank : 188)	NC score	0.169444 (rank : 162)
Query Neighborhood Hits	376	Target Neighborhood Hits	131	Shared Neighborhood Hits	94
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

RASA3_HUMAN
θ value	0.279714 (rank : 189)	NC score	0.233808 (rank : 86)
Query Neighborhood Hits	376	Target Neighborhood Hits	166	Shared Neighborhood Hits	78
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

RNPS1_HUMAN
θ value	0.279714 (rank : 190)	NC score	0.041292 (rank : 388)
Query Neighborhood Hits	376	Target Neighborhood Hits	285	Shared Neighborhood Hits	22
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
θ value	0.279714 (rank : 191)	NC score	0.041292 (rank : 389)
Query Neighborhood Hits	376	Target Neighborhood Hits	285	Shared Neighborhood Hits	22
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

SON_MOUSE
θ value	0.279714 (rank : 192)	NC score	0.061880 (rank : 328)
Query Neighborhood Hits	376	Target Neighborhood Hits	957	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

WWP1_HUMAN
θ value	0.279714 (rank : 193)	NC score	0.080637 (rank : 285)
Query Neighborhood Hits	376	Target Neighborhood Hits	262	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

ZO1_MOUSE
θ value	0.279714 (rank : 194)	NC score	0.166738 (rank : 167)
Query Neighborhood Hits	376	Target Neighborhood Hits	453	Shared Neighborhood Hits	110
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

CXCC1_MOUSE
θ value	0.365318 (rank : 195)	NC score	0.049744 (rank : 373)
Query Neighborhood Hits	376	Target Neighborhood Hits	124	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

MAGI2_HUMAN
θ value	0.365318 (rank : 196)	NC score	0.185734 (rank : 135)
Query Neighborhood Hits	376	Target Neighborhood Hits	373	Shared Neighborhood Hits	118
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MAGI2_MOUSE
θ value	0.365318 (rank : 197)	NC score	0.189343 (rank : 125)
Query Neighborhood Hits	376	Target Neighborhood Hits	370	Shared Neighborhood Hits	122
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

PA24A_HUMAN
θ value	0.365318 (rank : 198)	NC score	0.187094 (rank : 130)
Query Neighborhood Hits	376	Target Neighborhood Hits	88	Shared Neighborhood Hits	77
SwissProt Accessions	P47712	Gene names	PLA2G4A, CPLA2, PLA2G4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

PA24A_MOUSE
θ value	0.365318 (rank : 199)	NC score	0.194755 (rank : 118)
Query Neighborhood Hits	376	Target Neighborhood Hits	100	Shared Neighborhood Hits	78
SwissProt Accessions	P47713	Gene names	Pla2g4a, Cpla2, Pla2g4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

PA24D_HUMAN
θ value	0.365318 (rank : 200)	NC score	0.242258 (rank : 80)
Query Neighborhood Hits	376	Target Neighborhood Hits	97	Shared Neighborhood Hits	81
SwissProt Accessions	Q86XP0, Q8N176	Gene names	PLA2G4D
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

PAR6B_MOUSE
θ value	0.365318 (rank : 201)	NC score	0.164416 (rank : 173)
Query Neighborhood Hits	376	Target Neighborhood Hits	128	Shared Neighborhood Hits	83
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

RPTN_HUMAN
θ value	0.365318 (rank : 202)	NC score	0.053363 (rank : 357)
Query Neighborhood Hits	376	Target Neighborhood Hits	406	Shared Neighborhood Hits	63
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

EEA1_HUMAN
θ value	0.47712 (rank : 203)	NC score	0.028332 (rank : 422)
Query Neighborhood Hits	376	Target Neighborhood Hits	1796	Shared Neighborhood Hits	81
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

FMR1_MOUSE
θ value	0.47712 (rank : 204)	NC score	0.020718 (rank : 444)
Query Neighborhood Hits	376	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	P35922	Gene names	Fmr1, Fmr-1
Domain Architecture
Description	Fragile X mental retardation protein 1 homolog (Protein FMR-1) (FMRP) (mFmr1p).

HRX_HUMAN
θ value	0.47712 (rank : 205)	NC score	0.043880 (rank : 383)
Query Neighborhood Hits	376	Target Neighborhood Hits	825	Shared Neighborhood Hits	68
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

IWS1_HUMAN
θ value	0.47712 (rank : 206)	NC score	0.084827 (rank : 275)
Query Neighborhood Hits	376	Target Neighborhood Hits	1241	Shared Neighborhood Hits	101
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

JHD1B_MOUSE
θ value	0.47712 (rank : 207)	NC score	0.019668 (rank : 446)
Query Neighborhood Hits	376	Target Neighborhood Hits	214	Shared Neighborhood Hits	25
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

MPP4_HUMAN
θ value	0.47712 (rank : 208)	NC score	0.126718 (rank : 205)
Query Neighborhood Hits	376	Target Neighborhood Hits	205	Shared Neighborhood Hits	92
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

PAR6B_HUMAN
θ value	0.47712 (rank : 209)	NC score	0.165890 (rank : 170)
Query Neighborhood Hits	376	Target Neighborhood Hits	126	Shared Neighborhood Hits	82
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PEPL_MOUSE
θ value	0.47712 (rank : 210)	NC score	0.025914 (rank : 427)
Query Neighborhood Hits	376	Target Neighborhood Hits	1105	Shared Neighborhood Hits	66
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

PRP4B_MOUSE
θ value	0.47712 (rank : 211)	NC score	0.025743 (rank : 428)
Query Neighborhood Hits	376	Target Neighborhood Hits	1040	Shared Neighborhood Hits	58
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

FBXW7_HUMAN
θ value	0.62314 (rank : 212)	NC score	0.006811 (rank : 481)
Query Neighborhood Hits	376	Target Neighborhood Hits	433	Shared Neighborhood Hits	14
SwissProt Accessions	Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6	Gene names	FBXW7, FBW7, FBX30, SEL10
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10).

GRIP1_MOUSE
θ value	0.62314 (rank : 213)	NC score	0.188529 (rank : 128)
Query Neighborhood Hits	376	Target Neighborhood Hits	241	Shared Neighborhood Hits	109
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

HGS_HUMAN
θ value	0.62314 (rank : 214)	NC score	0.034621 (rank : 403)
Query Neighborhood Hits	376	Target Neighborhood Hits	517	Shared Neighborhood Hits	36
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

MAGI1_MOUSE
θ value	0.62314 (rank : 215)	NC score	0.198530 (rank : 114)
Query Neighborhood Hits	376	Target Neighborhood Hits	403	Shared Neighborhood Hits	143
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

RGS12_HUMAN
θ value	0.62314 (rank : 216)	NC score	0.090565 (rank : 263)
Query Neighborhood Hits	376	Target Neighborhood Hits	333	Shared Neighborhood Hits	85
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

SFRIP_HUMAN
θ value	0.62314 (rank : 217)	NC score	0.091219 (rank : 261)
Query Neighborhood Hits	376	Target Neighborhood Hits	530	Shared Neighborhood Hits	70
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

SFRS4_MOUSE
θ value	0.62314 (rank : 218)	NC score	0.049170 (rank : 376)
Query Neighborhood Hits	376	Target Neighborhood Hits	406	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

TARA_HUMAN
θ value	0.62314 (rank : 219)	NC score	0.084755 (rank : 276)
Query Neighborhood Hits	376	Target Neighborhood Hits	1626	Shared Neighborhood Hits	123
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ZO2_MOUSE
θ value	0.62314 (rank : 220)	NC score	0.167869 (rank : 164)
Query Neighborhood Hits	376	Target Neighborhood Hits	296	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

APBA1_HUMAN
θ value	0.813845 (rank : 221)	NC score	0.119461 (rank : 213)
Query Neighborhood Hits	376	Target Neighborhood Hits	325	Shared Neighborhood Hits	99
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

CD008_HUMAN
θ value	0.813845 (rank : 222)	NC score	0.041278 (rank : 390)
Query Neighborhood Hits	376	Target Neighborhood Hits	330	Shared Neighborhood Hits	34
SwissProt Accessions	P78312, O43607, P78311, P78313, Q9UEG8	Gene names	C4orf8
Domain Architecture	No domain graphic available
Description	Protein C4orf8 (Protein IT14).

DYSF_HUMAN
θ value	0.813845 (rank : 223)	NC score	0.242389 (rank : 79)
Query Neighborhood Hits	376	Target Neighborhood Hits	170	Shared Neighborhood Hits	106
SwissProt Accessions	O75923, O75696, Q9UEN7	Gene names	DYSF, FER1L1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

DYSF_MOUSE
θ value	0.813845 (rank : 224)	NC score	0.230453 (rank : 87)
Query Neighborhood Hits	376	Target Neighborhood Hits	162	Shared Neighborhood Hits	101
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

ITSN2_MOUSE
θ value	0.813845 (rank : 225)	NC score	0.128799 (rank : 200)
Query Neighborhood Hits	376	Target Neighborhood Hits	1371	Shared Neighborhood Hits	149
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

LRC49_HUMAN
θ value	0.813845 (rank : 226)	NC score	0.020890 (rank : 443)
Query Neighborhood Hits	376	Target Neighborhood Hits	210	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IUZ0, Q9NXM6	Gene names	LRRC49
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 49 (Tubulin polyglutamylase complex subunit 4) (PGs4).

MERL_MOUSE
θ value	0.813845 (rank : 227)	NC score	0.034487 (rank : 405)
Query Neighborhood Hits	376	Target Neighborhood Hits	524	Shared Neighborhood Hits	46
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

MINT_HUMAN
θ value	0.813845 (rank : 228)	NC score	0.053001 (rank : 360)
Query Neighborhood Hits	376	Target Neighborhood Hits	1291	Shared Neighborhood Hits	91
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SDCB1_MOUSE
θ value	0.813845 (rank : 229)	NC score	0.116018 (rank : 220)
Query Neighborhood Hits	376	Target Neighborhood Hits	144	Shared Neighborhood Hits	77
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

SETD2_HUMAN
θ value	0.813845 (rank : 230)	NC score	0.046025 (rank : 380)
Query Neighborhood Hits	376	Target Neighborhood Hits	412	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

EEA1_MOUSE
θ value	1.06291 (rank : 231)	NC score	0.025710 (rank : 429)
Query Neighborhood Hits	376	Target Neighborhood Hits	1637	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

GIPC2_MOUSE
θ value	1.06291 (rank : 232)	NC score	0.079417 (rank : 287)
Query Neighborhood Hits	376	Target Neighborhood Hits	71	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Z2H7, Q9CVG2	Gene names	Gipc2, Semcap2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain- associated protein 2) (SEMCAP-2).

GRIP2_HUMAN
θ value	1.06291 (rank : 233)	NC score	0.192009 (rank : 120)
Query Neighborhood Hits	376	Target Neighborhood Hits	256	Shared Neighborhood Hits	106
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

HMMR_MOUSE
θ value	1.06291 (rank : 234)	NC score	0.021277 (rank : 442)
Query Neighborhood Hits	376	Target Neighborhood Hits	1178	Shared Neighborhood Hits	62
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

K1849_HUMAN
θ value	1.06291 (rank : 235)	NC score	0.160397 (rank : 175)
Query Neighborhood Hits	376	Target Neighborhood Hits	220	Shared Neighborhood Hits	98
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

LRP2_HUMAN
θ value	1.06291 (rank : 236)	NC score	0.002287 (rank : 491)
Query Neighborhood Hits	376	Target Neighborhood Hits	573	Shared Neighborhood Hits	6
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

PA24E_HUMAN
θ value	1.06291 (rank : 237)	NC score	0.189157 (rank : 126)
Query Neighborhood Hits	376	Target Neighborhood Hits	89	Shared Neighborhood Hits	72
SwissProt Accessions	Q3MJ16, Q6ZSC0	Gene names	PLA2G4E
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

RAD50_HUMAN
θ value	1.06291 (rank : 238)	NC score	0.025547 (rank : 431)
Query Neighborhood Hits	376	Target Neighborhood Hits	1317	Shared Neighborhood Hits	70
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

RUFY2_MOUSE
θ value	1.06291 (rank : 239)	NC score	0.029242 (rank : 417)
Query Neighborhood Hits	376	Target Neighborhood Hits	820	Shared Neighborhood Hits	43
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

CXCC1_HUMAN
θ value	1.38821 (rank : 240)	NC score	0.039905 (rank : 392)
Query Neighborhood Hits	376	Target Neighborhood Hits	143	Shared Neighborhood Hits	15
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

GOGA4_MOUSE
θ value	1.38821 (rank : 241)	NC score	0.025208 (rank : 433)
Query Neighborhood Hits	376	Target Neighborhood Hits	1939	Shared Neighborhood Hits	96
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

INCE_HUMAN
θ value	1.38821 (rank : 242)	NC score	0.030838 (rank : 411)
Query Neighborhood Hits	376	Target Neighborhood Hits	978	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

INCE_MOUSE
θ value	1.38821 (rank : 243)	NC score	0.032226 (rank : 407)
Query Neighborhood Hits	376	Target Neighborhood Hits	903	Shared Neighborhood Hits	64
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

IWS1_MOUSE
θ value	1.38821 (rank : 244)	NC score	0.079026 (rank : 288)
Query Neighborhood Hits	376	Target Neighborhood Hits	1258	Shared Neighborhood Hits	103
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MERL_HUMAN
θ value	1.38821 (rank : 245)	NC score	0.032027 (rank : 409)
Query Neighborhood Hits	376	Target Neighborhood Hits	532	Shared Neighborhood Hits	47
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

MYOF_HUMAN
θ value	1.38821 (rank : 246)	NC score	0.228369 (rank : 91)
Query Neighborhood Hits	376	Target Neighborhood Hits	147	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NZM1, Q9HBU3, Q9NZM0, Q9ULL3, Q9Y4U4	Gene names	FER1L3, KIAA1207, MYOF
Domain Architecture
Description	Myoferlin (Fer-1-like protein 3).

SDCB1_HUMAN
θ value	1.38821 (rank : 247)	NC score	0.113063 (rank : 229)
Query Neighborhood Hits	376	Target Neighborhood Hits	150	Shared Neighborhood Hits	84
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

SYT14_HUMAN
θ value	1.38821 (rank : 248)	NC score	0.353923 (rank : 60)
Query Neighborhood Hits	376	Target Neighborhood Hits	81	Shared Neighborhood Hits	60
SwissProt Accessions	Q8NB59, Q5THX7, Q707N3, Q707N4, Q707N5, Q707N6, Q707N7	Gene names	SYT14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

AHTF1_MOUSE
θ value	1.81305 (rank : 249)	NC score	0.035226 (rank : 400)
Query Neighborhood Hits	376	Target Neighborhood Hits	176	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CJF7, Q8BVJ5, Q8VD55	Gene names	Ahctf1, Elys
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

BAIP3_HUMAN
θ value	1.81305 (rank : 250)	NC score	0.316694 (rank : 67)
Query Neighborhood Hits	376	Target Neighborhood Hits	108	Shared Neighborhood Hits	80
SwissProt Accessions	O94812, O94839, Q2M226, Q658J2, Q76N05, Q96RZ3, Q9UJK1	Gene names	BAIAP3, KIAA0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

CIR_HUMAN
θ value	1.81305 (rank : 251)	NC score	0.041058 (rank : 391)
Query Neighborhood Hits	376	Target Neighborhood Hits	249	Shared Neighborhood Hits	32
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

CROP_MOUSE
θ value	1.81305 (rank : 252)	NC score	0.057058 (rank : 340)
Query Neighborhood Hits	376	Target Neighborhood Hits	403	Shared Neighborhood Hits	47
SwissProt Accessions	Q5SUF2, Q3U9D5, Q8BUJ5, Q921Z3, Q9CRS7, Q9CTY4	Gene names	Crop
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein.

EVI1_HUMAN
θ value	1.81305 (rank : 253)	NC score	-0.005292 (rank : 494)
Query Neighborhood Hits	376	Target Neighborhood Hits	924	Shared Neighborhood Hits	18
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.

GIPC2_HUMAN
θ value	1.81305 (rank : 254)	NC score	0.093739 (rank : 256)
Query Neighborhood Hits	376	Target Neighborhood Hits	93	Shared Neighborhood Hits	67
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

ITCH_MOUSE
θ value	1.81305 (rank : 255)	NC score	0.071022 (rank : 305)
Query Neighborhood Hits	376	Target Neighborhood Hits	127	Shared Neighborhood Hits	33
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

LNX1_HUMAN
θ value	1.81305 (rank : 256)	NC score	0.185654 (rank : 136)
Query Neighborhood Hits	376	Target Neighborhood Hits	379	Shared Neighborhood Hits	104
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

NKTR_HUMAN
θ value	1.81305 (rank : 257)	NC score	0.052609 (rank : 363)
Query Neighborhood Hits	376	Target Neighborhood Hits	658	Shared Neighborhood Hits	95
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

NOS1_HUMAN
θ value	1.81305 (rank : 258)	NC score	0.097212 (rank : 252)
Query Neighborhood Hits	376	Target Neighborhood Hits	218	Shared Neighborhood Hits	92
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

SNIP1_HUMAN
θ value	1.81305 (rank : 259)	NC score	0.038908 (rank : 393)
Query Neighborhood Hits	376	Target Neighborhood Hits	80	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TAD8, Q96SP9, Q9H9T7	Gene names	SNIP1
Domain Architecture
Description	Smad nuclear-interacting protein 1.

ATRX_HUMAN
θ value	2.36792 (rank : 260)	NC score	0.034597 (rank : 404)
Query Neighborhood Hits	376	Target Neighborhood Hits	842	Shared Neighborhood Hits	67
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

CCD55_MOUSE
θ value	2.36792 (rank : 261)	NC score	0.093061 (rank : 257)
Query Neighborhood Hits	376	Target Neighborhood Hits	519	Shared Neighborhood Hits	96
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CLC4F_MOUSE
θ value	2.36792 (rank : 262)	NC score	0.009385 (rank : 473)
Query Neighborhood Hits	376	Target Neighborhood Hits	572	Shared Neighborhood Hits	27
SwissProt Accessions	P70194, Q8BLZ8	Gene names	Clec4f, Clecsf13, Kclr
Domain Architecture
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13) (Kupffer cell receptor).

DLG3_HUMAN
θ value	2.36792 (rank : 263)	NC score	0.180280 (rank : 145)
Query Neighborhood Hits	376	Target Neighborhood Hits	269	Shared Neighborhood Hits	103
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG3_MOUSE
θ value	2.36792 (rank : 264)	NC score	0.180993 (rank : 143)
Query Neighborhood Hits	376	Target Neighborhood Hits	274	Shared Neighborhood Hits	104
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

DVL2_MOUSE
θ value	2.36792 (rank : 265)	NC score	0.112138 (rank : 233)
Query Neighborhood Hits	376	Target Neighborhood Hits	233	Shared Neighborhood Hits	86
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL3_HUMAN
θ value	2.36792 (rank : 266)	NC score	0.116518 (rank : 219)
Query Neighborhood Hits	376	Target Neighborhood Hits	194	Shared Neighborhood Hits	85
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_MOUSE
θ value	2.36792 (rank : 267)	NC score	0.117718 (rank : 215)
Query Neighborhood Hits	376	Target Neighborhood Hits	198	Shared Neighborhood Hits	89
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

LIRB2_HUMAN
θ value	2.36792 (rank : 268)	NC score	0.009024 (rank : 475)
Query Neighborhood Hits	376	Target Neighborhood Hits	103	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N423, O75017, Q8NHJ7, Q8NHJ8	Gene names	LILRB2, ILT4, LIR2, MIR10
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 2 precursor (Leukocyte immunoglobulin-like receptor 2) (LIR-2) (Immunoglobulin- like transcript 4) (ILT-4) (Monocyte/macrophage immunoglobulin-like receptor 10) (MIR-10) (CD85d antigen).

M4K4_HUMAN
θ value	2.36792 (rank : 269)	NC score	0.014567 (rank : 459)
Query Neighborhood Hits	376	Target Neighborhood Hits	1589	Shared Neighborhood Hits	75
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MGRN1_HUMAN
θ value	2.36792 (rank : 270)	NC score	0.018999 (rank : 451)
Query Neighborhood Hits	376	Target Neighborhood Hits	192	Shared Neighborhood Hits	12
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

MYST4_MOUSE
θ value	2.36792 (rank : 271)	NC score	0.027689 (rank : 425)
Query Neighborhood Hits	376	Target Neighborhood Hits	416	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

PDZK4_MOUSE
θ value	2.36792 (rank : 272)	NC score	0.114385 (rank : 225)
Query Neighborhood Hits	376	Target Neighborhood Hits	165	Shared Neighborhood Hits	92
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

RFIP2_HUMAN
θ value	2.36792 (rank : 273)	NC score	0.213126 (rank : 101)
Query Neighborhood Hits	376	Target Neighborhood Hits	97	Shared Neighborhood Hits	70
SwissProt Accessions	Q7L804, Q9Y2F0	Gene names	RAB11FIP2, KIAA0941
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11).

SNUT3_HUMAN
θ value	2.36792 (rank : 274)	NC score	0.081674 (rank : 283)
Query Neighborhood Hits	376	Target Neighborhood Hits	52	Shared Neighborhood Hits	17
SwissProt Accessions	Q8WVK2, Q15410	Gene names
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 3 (U4/U6.U5 tri-snRNP-associated 27 kDa protein) (27K) (Nucleic acid-binding protein RY-1).

SYNP2_MOUSE
θ value	2.36792 (rank : 275)	NC score	0.082872 (rank : 278)
Query Neighborhood Hits	376	Target Neighborhood Hits	252	Shared Neighborhood Hits	74
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

SYT14_MOUSE
θ value	2.36792 (rank : 276)	NC score	0.355148 (rank : 59)
Query Neighborhood Hits	376	Target Neighborhood Hits	82	Shared Neighborhood Hits	62
SwissProt Accessions	Q7TN84	Gene names	Syt14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

VDR_HUMAN
θ value	2.36792 (rank : 277)	NC score	0.004916 (rank : 486)
Query Neighborhood Hits	376	Target Neighborhood Hits	112	Shared Neighborhood Hits	4
SwissProt Accessions	P11473	Gene names	VDR, NR1I1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

ZN366_HUMAN
θ value	2.36792 (rank : 278)	NC score	-0.007757 (rank : 498)
Query Neighborhood Hits	376	Target Neighborhood Hits	732	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N895, Q7RTV4	Gene names	ZNF366
Domain Architecture	No domain graphic available
Description	Zinc finger protein 366.

APXL_HUMAN
θ value	3.0926 (rank : 279)	NC score	0.098125 (rank : 250)
Query Neighborhood Hits	376	Target Neighborhood Hits	553	Shared Neighborhood Hits	82
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

CCD55_HUMAN
θ value	3.0926 (rank : 280)	NC score	0.089212 (rank : 266)
Query Neighborhood Hits	376	Target Neighborhood Hits	513	Shared Neighborhood Hits	91
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CN037_MOUSE
θ value	3.0926 (rank : 281)	NC score	0.021883 (rank : 439)
Query Neighborhood Hits	376	Target Neighborhood Hits	179	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

DDX23_HUMAN
θ value	3.0926 (rank : 282)	NC score	0.006962 (rank : 480)
Query Neighborhood Hits	376	Target Neighborhood Hits	486	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

EP400_MOUSE
θ value	3.0926 (rank : 283)	NC score	0.019217 (rank : 449)
Query Neighborhood Hits	376	Target Neighborhood Hits	592	Shared Neighborhood Hits	37
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

FIP1_HUMAN
θ value	3.0926 (rank : 284)	NC score	0.031325 (rank : 410)
Query Neighborhood Hits	376	Target Neighborhood Hits	118	Shared Neighborhood Hits	25
SwissProt Accessions	Q6UN15, Q499Y4, Q49AU3, Q7Z608, Q8WVN3, Q96F80, Q9H077	Gene names	FIP1L1, FIP1, RHE
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1) (Factor interacting with PAP) (hFip1) (Rearranged in hypereosinophilia).

FIP1_MOUSE
θ value	3.0926 (rank : 285)	NC score	0.029427 (rank : 416)
Query Neighborhood Hits	376	Target Neighborhood Hits	120	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D824, Q8BWX7, Q99LH0, Q9DBB2	Gene names	Fip1l1
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1).

MINK1_MOUSE
θ value	3.0926 (rank : 286)	NC score	0.013718 (rank : 460)
Query Neighborhood Hits	376	Target Neighborhood Hits	1451	Shared Neighborhood Hits	66
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MKRN3_HUMAN
θ value	3.0926 (rank : 287)	NC score	0.016617 (rank : 455)
Query Neighborhood Hits	376	Target Neighborhood Hits	165	Shared Neighborhood Hits	9
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

MY18A_HUMAN
θ value	3.0926 (rank : 288)	NC score	0.037532 (rank : 395)
Query Neighborhood Hits	376	Target Neighborhood Hits	1929	Shared Neighborhood Hits	167
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PA24F_HUMAN
θ value	3.0926 (rank : 289)	NC score	0.141627 (rank : 184)
Query Neighborhood Hits	376	Target Neighborhood Hits	78	Shared Neighborhood Hits	62
SwissProt Accessions	Q68DD2, Q6ZMC8	Gene names	PLA2G4F
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

PININ_HUMAN
θ value	3.0926 (rank : 290)	NC score	0.047141 (rank : 379)
Query Neighborhood Hits	376	Target Neighborhood Hits	753	Shared Neighborhood Hits	82
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

RUFY2_HUMAN
θ value	3.0926 (rank : 291)	NC score	0.025460 (rank : 432)
Query Neighborhood Hits	376	Target Neighborhood Hits	1208	Shared Neighborhood Hits	64
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

SRCH_HUMAN
θ value	3.0926 (rank : 292)	NC score	0.047868 (rank : 378)
Query Neighborhood Hits	376	Target Neighborhood Hits	225	Shared Neighborhood Hits	28
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

TCRG1_HUMAN
θ value	3.0926 (rank : 293)	NC score	0.060880 (rank : 335)
Query Neighborhood Hits	376	Target Neighborhood Hits	929	Shared Neighborhood Hits	93
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	3.0926 (rank : 294)	NC score	0.060880 (rank : 334)
Query Neighborhood Hits	376	Target Neighborhood Hits	947	Shared Neighborhood Hits	95
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TRI40_HUMAN
θ value	3.0926 (rank : 295)	NC score	0.015522 (rank : 457)
Query Neighborhood Hits	376	Target Neighborhood Hits	279	Shared Neighborhood Hits	15
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

ANR38_MOUSE
θ value	4.03905 (rank : 296)	NC score	0.010179 (rank : 471)
Query Neighborhood Hits	376	Target Neighborhood Hits	512	Shared Neighborhood Hits	32
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ARFG3_MOUSE
θ value	4.03905 (rank : 297)	NC score	0.013376 (rank : 464)
Query Neighborhood Hits	376	Target Neighborhood Hits	80	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

CCNL1_MOUSE
θ value	4.03905 (rank : 298)	NC score	0.028955 (rank : 419)
Query Neighborhood Hits	376	Target Neighborhood Hits	71	Shared Neighborhood Hits	19
SwissProt Accessions	Q52KE7, Q8BQ75, Q8R5H9, Q922K0, Q9CSZ3, Q9WV44	Gene names	Ccnl1, Ania6a, Ccn1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L) (Cyclin Ania-6a).

CD2L1_MOUSE
θ value	4.03905 (rank : 299)	NC score	0.016213 (rank : 456)
Query Neighborhood Hits	376	Target Neighborhood Hits	1463	Shared Neighborhood Hits	77
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

CDSN_MOUSE
θ value	4.03905 (rank : 300)	NC score	0.026789 (rank : 426)
Query Neighborhood Hits	376	Target Neighborhood Hits	131	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TPC1	Gene names	Cdsn
Domain Architecture	No domain graphic available
Description	Corneodesmosin precursor.

GON4L_HUMAN
θ value	4.03905 (rank : 301)	NC score	0.032193 (rank : 408)
Query Neighborhood Hits	376	Target Neighborhood Hits	555	Shared Neighborhood Hits	44
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

LRC49_MOUSE
θ value	4.03905 (rank : 302)	NC score	0.017800 (rank : 453)
Query Neighborhood Hits	376	Target Neighborhood Hits	230	Shared Neighborhood Hits	7
SwissProt Accessions	Q91YK0, Q8C3S4, Q8C7T7	Gene names	Lrrc49
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 49 (Tubulin polyglutamylase complex subunit 4) (PGs4) (p79).

PAX1_MOUSE
θ value	4.03905 (rank : 303)	NC score	0.005139 (rank : 484)
Query Neighborhood Hits	376	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	P09084, Q9R2B1	Gene names	Pax1, Pax-1
Domain Architecture
Description	Paired box protein Pax-1.

RAI1_MOUSE
θ value	4.03905 (rank : 304)	NC score	0.034713 (rank : 402)
Query Neighborhood Hits	376	Target Neighborhood Hits	344	Shared Neighborhood Hits	23
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

SYJ2B_HUMAN
θ value	4.03905 (rank : 305)	NC score	0.201640 (rank : 112)
Query Neighborhood Hits	376	Target Neighborhood Hits	162	Shared Neighborhood Hits	97
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

T22D2_HUMAN
θ value	4.03905 (rank : 306)	NC score	0.028562 (rank : 420)
Query Neighborhood Hits	376	Target Neighborhood Hits	250	Shared Neighborhood Hits	14
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

ZBT37_HUMAN
θ value	4.03905 (rank : 307)	NC score	-0.007522 (rank : 496)
Query Neighborhood Hits	376	Target Neighborhood Hits	815	Shared Neighborhood Hits	8
SwissProt Accessions	Q5TC79, Q5TC80, Q96M87, Q9BQ88	Gene names	ZBTB37
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 37.

BAIP3_MOUSE
θ value	5.27518 (rank : 308)	NC score	0.308185 (rank : 68)
Query Neighborhood Hits	376	Target Neighborhood Hits	112	Shared Neighborhood Hits	83
SwissProt Accessions	Q80TT2, Q6RUT4	Gene names	Baiap3, Gm937, Kiaa0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

CCD93_HUMAN
θ value	5.27518 (rank : 309)	NC score	0.019261 (rank : 447)
Query Neighborhood Hits	376	Target Neighborhood Hits	600	Shared Neighborhood Hits	40
SwissProt Accessions	Q567U6, Q4LE78, Q53TJ2, Q8TBX5, Q9H6R5, Q9NV15	Gene names	CCDC93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

CDC37_HUMAN
θ value	5.27518 (rank : 310)	NC score	0.030023 (rank : 413)
Query Neighborhood Hits	376	Target Neighborhood Hits	506	Shared Neighborhood Hits	50
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

CSPG2_MOUSE
θ value	5.27518 (rank : 311)	NC score	0.003361 (rank : 490)
Query Neighborhood Hits	376	Target Neighborhood Hits	711	Shared Neighborhood Hits	22
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

DJBP_MOUSE
θ value	5.27518 (rank : 312)	NC score	0.012137 (rank : 465)
Query Neighborhood Hits	376	Target Neighborhood Hits	152	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P1E8, Q5DTV8, Q6PGK8, Q9D2D8	Gene names	Djbp, Kiaa1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein.

DNMT1_HUMAN
θ value	5.27518 (rank : 313)	NC score	0.037515 (rank : 396)
Query Neighborhood Hits	376	Target Neighborhood Hits	401	Shared Neighborhood Hits	55
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

JPH2_MOUSE
θ value	5.27518 (rank : 314)	NC score	0.013451 (rank : 463)
Query Neighborhood Hits	376	Target Neighborhood Hits	279	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

MYST4_HUMAN
θ value	5.27518 (rank : 315)	NC score	0.027972 (rank : 424)
Query Neighborhood Hits	376	Target Neighborhood Hits	671	Shared Neighborhood Hits	52
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

NCOA1_HUMAN
θ value	5.27518 (rank : 316)	NC score	0.011135 (rank : 467)
Query Neighborhood Hits	376	Target Neighborhood Hits	198	Shared Neighborhood Hits	17
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

PRDM8_MOUSE
θ value	5.27518 (rank : 317)	NC score	0.009193 (rank : 474)
Query Neighborhood Hits	376	Target Neighborhood Hits	176	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BZ97	Gene names	Prdm8
Domain Architecture	No domain graphic available
Description	PR domain zinc finger protein 8 (PR domain-containing protein 8).

RAI1_HUMAN
θ value	5.27518 (rank : 318)	NC score	0.033623 (rank : 406)
Query Neighborhood Hits	376	Target Neighborhood Hits	360	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

TIAM1_MOUSE
θ value	5.27518 (rank : 319)	NC score	0.024581 (rank : 434)
Query Neighborhood Hits	376	Target Neighborhood Hits	205	Shared Neighborhood Hits	32
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

ZN212_HUMAN
θ value	5.27518 (rank : 320)	NC score	-0.007551 (rank : 497)
Query Neighborhood Hits	376	Target Neighborhood Hits	699	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UDV6, Q13396, Q8N664	Gene names	ZNF212, ZNFC150
Domain Architecture	No domain graphic available
Description	Zinc finger protein 212 (Zinc finger protein C2H2-150).

BRAF1_HUMAN
θ value	6.88961 (rank : 321)	NC score	0.010619 (rank : 469)
Query Neighborhood Hits	376	Target Neighborhood Hits	883	Shared Neighborhood Hits	21
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

BRE1A_HUMAN
θ value	6.88961 (rank : 322)	NC score	0.018002 (rank : 452)
Query Neighborhood Hits	376	Target Neighborhood Hits	1071	Shared Neighborhood Hits	65
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

CAC1A_MOUSE
θ value	6.88961 (rank : 323)	NC score	0.005100 (rank : 485)
Query Neighborhood Hits	376	Target Neighborhood Hits	267	Shared Neighborhood Hits	26
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CCNL1_HUMAN
θ value	6.88961 (rank : 324)	NC score	0.028255 (rank : 423)
Query Neighborhood Hits	376	Target Neighborhood Hits	79	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UK58, Q6NVY9, Q6UWS7, Q8NI48, Q96QT0, Q9NZF3	Gene names	CCNL1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L).

CD2L1_HUMAN
θ value	6.88961 (rank : 325)	NC score	0.015112 (rank : 458)
Query Neighborhood Hits	376	Target Neighborhood Hits	1467	Shared Neighborhood Hits	74
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CDS1_HUMAN
θ value	6.88961 (rank : 326)	NC score	0.006389 (rank : 482)
Query Neighborhood Hits	376	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q92903, O00163	Gene names	CDS1, CDS
Domain Architecture
Description	Phosphatidate cytidylyltransferase 1 (EC 2.7.7.41) (CDP-diglyceride synthetase 1) (CDP-diglyceride pyrophosphorylase 1) (CDP- diacylglycerol synthase 1) (CDS 1) (CTP:phosphatidate cytidylyltransferase 1) (CDP-DAG synthase 1) (CDP-DG synthetase 1).

CPNE6_HUMAN
θ value	6.88961 (rank : 327)	NC score	0.082577 (rank : 280)
Query Neighborhood Hits	376	Target Neighborhood Hits	85	Shared Neighborhood Hits	56
SwissProt Accessions	O95741, Q53HA6, Q8WVG1	Gene names	CPNE6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

CROCC_HUMAN
θ value	6.88961 (rank : 328)	NC score	0.019239 (rank : 448)
Query Neighborhood Hits	376	Target Neighborhood Hits	1409	Shared Neighborhood Hits	81
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

DVL2_HUMAN
θ value	6.88961 (rank : 329)	NC score	0.109485 (rank : 237)
Query Neighborhood Hits	376	Target Neighborhood Hits	223	Shared Neighborhood Hits	89
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

FMN2_HUMAN
θ value	6.88961 (rank : 330)	NC score	0.017206 (rank : 454)
Query Neighborhood Hits	376	Target Neighborhood Hits	484	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

G45IP_MOUSE
θ value	6.88961 (rank : 331)	NC score	0.021459 (rank : 440)
Query Neighborhood Hits	376	Target Neighborhood Hits	68	Shared Neighborhood Hits	12
SwissProt Accessions	Q9CR59, Q8BT05	Gene names	Gadd45gip1
Domain Architecture	No domain graphic available
Description	Growth arrest and DNA-damage-inducible proteins-interacting protein 1.

GCM2_HUMAN
θ value	6.88961 (rank : 332)	NC score	0.010065 (rank : 472)
Query Neighborhood Hits	376	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	O75603	Gene names	GCM2, GCMB
Domain Architecture
Description	Chorion-specific transcription factor GCMb (Glial cells missing homolog 2) (GCM motif protein 2) (hGCMb).

GIPC3_HUMAN
θ value	6.88961 (rank : 333)	NC score	0.071271 (rank : 304)
Query Neighborhood Hits	376	Target Neighborhood Hits	52	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TF64, O75227	Gene names	GIPC3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3.

GIPC3_MOUSE
θ value	6.88961 (rank : 334)	NC score	0.072136 (rank : 302)
Query Neighborhood Hits	376	Target Neighborhood Hits	53	Shared Neighborhood Hits	39
SwissProt Accessions	Q8R5M0	Gene names	Gipc3, Rgs19ip3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3).

HIRP3_HUMAN
θ value	6.88961 (rank : 335)	NC score	0.041417 (rank : 387)
Query Neighborhood Hits	376	Target Neighborhood Hits	323	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

HMMR_HUMAN
θ value	6.88961 (rank : 336)	NC score	0.019148 (rank : 450)
Query Neighborhood Hits	376	Target Neighborhood Hits	1082	Shared Neighborhood Hits	54
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

ILDR1_HUMAN
θ value	6.88961 (rank : 337)	NC score	0.010653 (rank : 468)
Query Neighborhood Hits	376	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q86SU0, Q6ZP61, Q7Z578	Gene names	ILDR1
Domain Architecture	No domain graphic available
Description	Immunoglobulin-like domain-containing receptor 1 precursor.

LAD1_HUMAN
θ value	6.88961 (rank : 338)	NC score	0.041527 (rank : 386)
Query Neighborhood Hits	376	Target Neighborhood Hits	441	Shared Neighborhood Hits	46
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

LIRB1_HUMAN
θ value	6.88961 (rank : 339)	NC score	0.005908 (rank : 483)
Query Neighborhood Hits	376	Target Neighborhood Hits	116	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NHL6, O75024, O75025, Q8NHJ9, Q8NHK0	Gene names	LILRB1, ILT2, LIR1, MIR7
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 1 precursor (Leukocyte immunoglobulin-like receptor 1) (LIR-1) (Immunoglobulin- like transcript 2) (ILT-2) (Monocyte/macrophage immunoglobulin-like receptor 7) (MIR-7) (CD85j antigen).

PCNT_HUMAN
θ value	6.88961 (rank : 340)	NC score	0.028375 (rank : 421)
Query Neighborhood Hits	376	Target Neighborhood Hits	1551	Shared Neighborhood Hits	84
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

SC24D_HUMAN
θ value	6.88961 (rank : 341)	NC score	0.010384 (rank : 470)
Query Neighborhood Hits	376	Target Neighborhood Hits	173	Shared Neighborhood Hits	8
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

SFRS7_HUMAN
θ value	6.88961 (rank : 342)	NC score	0.023438 (rank : 436)
Query Neighborhood Hits	376	Target Neighborhood Hits	191	Shared Neighborhood Hits	18
SwissProt Accessions	Q16629	Gene names	SFRS7
Domain Architecture
Description	Splicing factor, arginine/serine-rich 7 (Splicing factor 9G8).

SNTG1_MOUSE
θ value	6.88961 (rank : 343)	NC score	0.154247 (rank : 177)
Query Neighborhood Hits	376	Target Neighborhood Hits	179	Shared Neighborhood Hits	100
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SNUT3_MOUSE
θ value	6.88961 (rank : 344)	NC score	0.074187 (rank : 295)
Query Neighborhood Hits	376	Target Neighborhood Hits	50	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K194, Q8BRA8, Q9CSV0	Gene names
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 3.

SYT13_MOUSE
θ value	6.88961 (rank : 345)	NC score	0.355736 (rank : 58)
Query Neighborhood Hits	376	Target Neighborhood Hits	69	Shared Neighborhood Hits	65
SwissProt Accessions	Q9EQT6, Q6ZPR2, Q8BRK6	Gene names	Syt13, Kiaa1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

WDR20_HUMAN
θ value	6.88961 (rank : 346)	NC score	0.004811 (rank : 487)
Query Neighborhood Hits	376	Target Neighborhood Hits	249	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TBZ3, Q8WXX2, Q9UF86	Gene names	WDR20
Domain Architecture
Description	WD repeat protein 20 (DMR protein).

ACHA4_HUMAN
θ value	8.99809 (rank : 347)	NC score	-0.000091 (rank : 492)
Query Neighborhood Hits	376	Target Neighborhood Hits	131	Shared Neighborhood Hits	5
SwissProt Accessions	P43681, Q4JGR7	Gene names	CHRNA4, NACRA4
Domain Architecture
Description	Neuronal acetylcholine receptor protein subunit alpha-4 precursor.

APBA2_HUMAN
θ value	8.99809 (rank : 348)	NC score	0.101920 (rank : 246)
Query Neighborhood Hits	376	Target Neighborhood Hits	220	Shared Neighborhood Hits	92
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_MOUSE
θ value	8.99809 (rank : 349)	NC score	0.112183 (rank : 232)
Query Neighborhood Hits	376	Target Neighborhood Hits	219	Shared Neighborhood Hits	92
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

CBX8_HUMAN
θ value	8.99809 (rank : 350)	NC score	0.007763 (rank : 477)
Query Neighborhood Hits	376	Target Neighborhood Hits	67	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HC52, Q96H39, Q9NR07	Gene names	CBX8, PC3, RC1
Domain Architecture
Description	Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (hPc3) (Rectachrome 1).

CHD9_MOUSE
θ value	8.99809 (rank : 351)	NC score	0.022815 (rank : 438)
Query Neighborhood Hits	376	Target Neighborhood Hits	427	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

CMGA_MOUSE
θ value	8.99809 (rank : 352)	NC score	0.022882 (rank : 437)
Query Neighborhood Hits	376	Target Neighborhood Hits	172	Shared Neighborhood Hits	28
SwissProt Accessions	P26339	Gene names	Chga
Domain Architecture
Description	Chromogranin A precursor (CgA) [Contains: Pancreastatin; Beta-granin; WE-14].

CPNE6_MOUSE
θ value	8.99809 (rank : 353)	NC score	0.081814 (rank : 282)
Query Neighborhood Hits	376	Target Neighborhood Hits	87	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z140	Gene names	Cpne6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

HDA10_HUMAN
θ value	8.99809 (rank : 354)	NC score	0.007534 (rank : 478)
Query Neighborhood Hits	376	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	Q969S8, Q6STF9, Q96P77, Q96P78, Q9H028, Q9UGX1, Q9UGX2	Gene names	HDAC10
Domain Architecture
Description	Histone deacetylase 10 (HD10).

HME1_MOUSE
θ value	8.99809 (rank : 355)	NC score	-0.003013 (rank : 493)
Query Neighborhood Hits	376	Target Neighborhood Hits	397	Shared Neighborhood Hits	7
SwissProt Accessions	P09065	Gene names	En1, En-1
Domain Architecture
Description	Homeobox protein engrailed-1 (Mo-En-1).

K0528_HUMAN
θ value	8.99809 (rank : 356)	NC score	0.269648 (rank : 73)
Query Neighborhood Hits	376	Target Neighborhood Hits	96	Shared Neighborhood Hits	76
SwissProt Accessions	Q86YS7, O60280, Q7Z619, Q86SU3	Gene names	KIAA0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

K0528_MOUSE
θ value	8.99809 (rank : 357)	NC score	0.270947 (rank : 72)
Query Neighborhood Hits	376	Target Neighborhood Hits	102	Shared Neighborhood Hits	78
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

LPP_HUMAN
θ value	8.99809 (rank : 358)	NC score	0.013683 (rank : 461)
Query Neighborhood Hits	376	Target Neighborhood Hits	775	Shared Neighborhood Hits	37
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

MAML3_HUMAN
θ value	8.99809 (rank : 359)	NC score	0.011743 (rank : 466)
Query Neighborhood Hits	376	Target Neighborhood Hits	323	Shared Neighborhood Hits	15
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

MAST3_HUMAN
θ value	8.99809 (rank : 360)	NC score	0.029672 (rank : 415)
Query Neighborhood Hits	376	Target Neighborhood Hits	1128	Shared Neighborhood Hits	88
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

NEB1_HUMAN
θ value	8.99809 (rank : 361)	NC score	0.135332 (rank : 193)
Query Neighborhood Hits	376	Target Neighborhood Hits	829	Shared Neighborhood Hits	143
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

NIN_HUMAN
θ value	8.99809 (rank : 362)	NC score	0.020468 (rank : 445)
Query Neighborhood Hits	376	Target Neighborhood Hits	1416	Shared Neighborhood Hits	73
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

PPIG_HUMAN
θ value	8.99809 (rank : 363)	NC score	0.043185 (rank : 385)
Query Neighborhood Hits	376	Target Neighborhood Hits	670	Shared Neighborhood Hits	87
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

PZRN4_HUMAN
θ value	8.99809 (rank : 364)	NC score	0.138648 (rank : 187)
Query Neighborhood Hits	376	Target Neighborhood Hits	438	Shared Neighborhood Hits	102
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

RNF19_MOUSE
θ value	8.99809 (rank : 365)	NC score	0.004688 (rank : 488)
Query Neighborhood Hits	376	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

RPGR1_HUMAN
θ value	8.99809 (rank : 366)	NC score	0.021418 (rank : 441)
Query Neighborhood Hits	376	Target Neighborhood Hits	578	Shared Neighborhood Hits	42
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

SCG1_MOUSE
θ value	8.99809 (rank : 367)	NC score	0.023820 (rank : 435)
Query Neighborhood Hits	376	Target Neighborhood Hits	163	Shared Neighborhood Hits	21
SwissProt Accessions	P16014	Gene names	Chgb, Scg-1, Scg1
Domain Architecture
Description	Secretogranin-1 precursor (Secretogranin I) (SgI) (Chromogranin B) (CgB).

SNTG1_HUMAN
θ value	8.99809 (rank : 368)	NC score	0.151952 (rank : 179)
Query Neighborhood Hits	376	Target Neighborhood Hits	181	Shared Neighborhood Hits	100
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SNX17_HUMAN
θ value	8.99809 (rank : 369)	NC score	0.007835 (rank : 476)
Query Neighborhood Hits	376	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q15036, Q53HN7, Q6IAS3	Gene names	SNX17, KIAA0064
Domain Architecture
Description	Sorting nexin-17.

STMN1_HUMAN
θ value	8.99809 (rank : 370)	NC score	0.037972 (rank : 394)
Query Neighborhood Hits	376	Target Neighborhood Hits	554	Shared Neighborhood Hits	59
SwissProt Accessions	P16949	Gene names	STMN1, LAP18, OP18
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22).

STMN1_MOUSE
θ value	8.99809 (rank : 371)	NC score	0.037127 (rank : 398)
Query Neighborhood Hits	376	Target Neighborhood Hits	560	Shared Neighborhood Hits	59
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

STX7_MOUSE
θ value	8.99809 (rank : 372)	NC score	0.007491 (rank : 479)
Query Neighborhood Hits	376	Target Neighborhood Hits	131	Shared Neighborhood Hits	14
SwissProt Accessions	O70439	Gene names	Stx7, Syn7
Domain Architecture
Description	Syntaxin-7.

TPR_HUMAN
θ value	8.99809 (rank : 373)	NC score	0.025698 (rank : 430)
Query Neighborhood Hits	376	Target Neighborhood Hits	1921	Shared Neighborhood Hits	97
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

ZFP37_MOUSE
θ value	8.99809 (rank : 374)	NC score	-0.006068 (rank : 495)
Query Neighborhood Hits	376	Target Neighborhood Hits	906	Shared Neighborhood Hits	37
SwissProt Accessions	P17141, Q62514	Gene names	Zfp37, Zfp-37
Domain Architecture
Description	Zinc finger protein 37 (Zfp-37) (Male germ cell-specific zinc finger protein).

ZFYV9_HUMAN
θ value	8.99809 (rank : 375)	NC score	0.013641 (rank : 462)
Query Neighborhood Hits	376	Target Neighborhood Hits	134	Shared Neighborhood Hits	11
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

ZN452_HUMAN
θ value	8.99809 (rank : 376)	NC score	0.003606 (rank : 489)
Query Neighborhood Hits	376	Target Neighborhood Hits	139	Shared Neighborhood Hits	7
SwissProt Accessions	Q6R2W3, Q2NKL9, Q5SRJ3, Q8TCN2, Q96PW3	Gene names	ZNF452, KIAA1925
Domain Architecture	No domain graphic available
Description	Protein ZNF452.

ACINU_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.052655 (rank : 362)
Query Neighborhood Hits	376	Target Neighborhood Hits	828	Shared Neighborhood Hits	91
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

APBA3_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.092911 (rank : 259)
Query Neighborhood Hits	376	Target Neighborhood Hits	201	Shared Neighborhood Hits	87
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

APBA3_MOUSE
θ value	θ > 10 (rank : 379)	NC score	0.085579 (rank : 273)
Query Neighborhood Hits	376	Target Neighborhood Hits	174	Shared Neighborhood Hits	82
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

ARHGB_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.072500 (rank : 300)
Query Neighborhood Hits	376	Target Neighborhood Hits	375	Shared Neighborhood Hits	95
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

ARHGC_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.065636 (rank : 314)
Query Neighborhood Hits	376	Target Neighborhood Hits	351	Shared Neighborhood Hits	91
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.065809 (rank : 312)
Query Neighborhood Hits	376	Target Neighborhood Hits	344	Shared Neighborhood Hits	93
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

BSN_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.085300 (rank : 274)
Query Neighborhood Hits	376	Target Neighborhood Hits	1537	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

BSN_MOUSE
θ value	θ > 10 (rank : 384)	NC score	0.089681 (rank : 265)
Query Neighborhood Hits	376	Target Neighborhood Hits	2057	Shared Neighborhood Hits	95
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

C8AP2_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.050691 (rank : 368)
Query Neighborhood Hits	376	Target Neighborhood Hits	548	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

CPNE1_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.090866 (rank : 262)
Query Neighborhood Hits	376	Target Neighborhood Hits	70	Shared Neighborhood Hits	54
SwissProt Accessions	Q99829, Q6IBL3, Q9H243, Q9NTZ7	Gene names	CPNE1, CPN1
Domain Architecture
Description	Copine-1 (Copine I).

CPNE1_MOUSE
θ value	θ > 10 (rank : 387)	NC score	0.109065 (rank : 238)
Query Neighborhood Hits	376	Target Neighborhood Hits	83	Shared Neighborhood Hits	61
SwissProt Accessions	Q8C166, Q925K4, Q925K5	Gene names	Cpne1
Domain Architecture
Description	Copine-1 (Copine I).

CPNE2_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.112363 (rank : 231)
Query Neighborhood Hits	376	Target Neighborhood Hits	75	Shared Neighborhood Hits	55
SwissProt Accessions	Q96FN4, Q68D19, Q86XP9	Gene names	CPNE2
Domain Architecture
Description	Copine-2 (Copine II).

CPNE2_MOUSE
θ value	θ > 10 (rank : 389)	NC score	0.112729 (rank : 230)
Query Neighborhood Hits	376	Target Neighborhood Hits	82	Shared Neighborhood Hits	58
SwissProt Accessions	P59108, Q8K1D7	Gene names	Cpne2
Domain Architecture
Description	Copine-2 (Copine II).

CPNE3_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.126512 (rank : 206)
Query Neighborhood Hits	376	Target Neighborhood Hits	90	Shared Neighborhood Hits	65
SwissProt Accessions	O75131, Q8IYA1	Gene names	CPNE3, CPN3, KIAA0636
Domain Architecture
Description	Copine-3 (Copine III).

CPNE3_MOUSE
θ value	θ > 10 (rank : 391)	NC score	0.125882 (rank : 207)
Query Neighborhood Hits	376	Target Neighborhood Hits	90	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BT60, Q5CZX9, Q5DU22	Gene names	Cpne3, Kiaa0636
Domain Architecture
Description	Copine-3 (Copine III).

CPNE4_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.073414 (rank : 297)
Query Neighborhood Hits	376	Target Neighborhood Hits	70	Shared Neighborhood Hits	50
SwissProt Accessions	Q96A23, Q8TEX1	Gene names	CPNE4
Domain Architecture
Description	Copine-4 (Copine IV) (Copine-8).

CPNE4_MOUSE
θ value	θ > 10 (rank : 393)	NC score	0.071940 (rank : 303)
Query Neighborhood Hits	376	Target Neighborhood Hits	67	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BLR2	Gene names	Cpne4
Domain Architecture	No domain graphic available
Description	Copine-4 (Copine IV).

CPNE5_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.117090 (rank : 217)
Query Neighborhood Hits	376	Target Neighborhood Hits	88	Shared Neighborhood Hits	62
SwissProt Accessions	Q9HCH3	Gene names	CPNE5, KIAA1599
Domain Architecture
Description	Copine-5 (Copine V).

CPNE5_MOUSE
θ value	θ > 10 (rank : 395)	NC score	0.117337 (rank : 216)
Query Neighborhood Hits	376	Target Neighborhood Hits	86	Shared Neighborhood Hits	62
SwissProt Accessions	Q8JZW4	Gene names	Cpne5
Domain Architecture
Description	Copine-5 (Copine V).

CPNE7_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.098284 (rank : 249)
Query Neighborhood Hits	376	Target Neighborhood Hits	92	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UBL6	Gene names	CPNE7
Domain Architecture
Description	Copine-7 (Copine VII).

CPNE8_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.113132 (rank : 228)
Query Neighborhood Hits	376	Target Neighborhood Hits	86	Shared Neighborhood Hits	62
SwissProt Accessions	Q86YQ8, Q2TB41	Gene names	CPNE8
Domain Architecture
Description	Copine-8 (Copine VIII).

CPNE8_MOUSE
θ value	θ > 10 (rank : 398)	NC score	0.110118 (rank : 236)
Query Neighborhood Hits	376	Target Neighborhood Hits	85	Shared Neighborhood Hits	62
SwissProt Accessions	Q9DC53, Q9CUZ8	Gene names	Cpne8
Domain Architecture
Description	Copine-8 (Copine VIII).

DVL1L_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.099951 (rank : 247)
Query Neighborhood Hits	376	Target Neighborhood Hits	146	Shared Neighborhood Hits	80
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

DVL1_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.108408 (rank : 239)
Query Neighborhood Hits	376	Target Neighborhood Hits	158	Shared Neighborhood Hits	85
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL1_MOUSE
θ value	θ > 10 (rank : 401)	NC score	0.106795 (rank : 240)
Query Neighborhood Hits	376	Target Neighborhood Hits	146	Shared Neighborhood Hits	83
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

ELOA1_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.056175 (rank : 348)
Query Neighborhood Hits	376	Target Neighborhood Hits	388	Shared Neighborhood Hits	71
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

EM55_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.087223 (rank : 271)
Query Neighborhood Hits	376	Target Neighborhood Hits	228	Shared Neighborhood Hits	89
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

EM55_MOUSE
θ value	θ > 10 (rank : 404)	NC score	0.087851 (rank : 269)
Query Neighborhood Hits	376	Target Neighborhood Hits	221	Shared Neighborhood Hits	89
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

FILA_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.050973 (rank : 367)
Query Neighborhood Hits	376	Target Neighborhood Hits	685	Shared Neighborhood Hits	82
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

GOPC_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.166005 (rank : 169)
Query Neighborhood Hits	376	Target Neighborhood Hits	377	Shared Neighborhood Hits	105
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

GOPC_MOUSE
θ value	θ > 10 (rank : 407)	NC score	0.169987 (rank : 161)
Query Neighborhood Hits	376	Target Neighborhood Hits	323	Shared Neighborhood Hits	102
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

GRASP_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.069404 (rank : 307)
Query Neighborhood Hits	376	Target Neighborhood Hits	147	Shared Neighborhood Hits	61
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

GRASP_MOUSE
θ value	θ > 10 (rank : 409)	NC score	0.065531 (rank : 315)
Query Neighborhood Hits	376	Target Neighborhood Hits	131	Shared Neighborhood Hits	57
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

GRP3_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.056529 (rank : 345)
Query Neighborhood Hits	376	Target Neighborhood Hits	131	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

HUWE1_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.052129 (rank : 365)
Query Neighborhood Hits	376	Target Neighborhood Hits	443	Shared Neighborhood Hits	34
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HUWE1_MOUSE
θ value	θ > 10 (rank : 412)	NC score	0.052050 (rank : 366)
Query Neighborhood Hits	376	Target Neighborhood Hits	406	Shared Neighborhood Hits	37
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

LEO1_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.053336 (rank : 358)
Query Neighborhood Hits	376	Target Neighborhood Hits	958	Shared Neighborhood Hits	86
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LIN7A_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.178443 (rank : 153)
Query Neighborhood Hits	376	Target Neighborhood Hits	193	Shared Neighborhood Hits	98
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
θ value	θ > 10 (rank : 415)	NC score	0.178408 (rank : 154)
Query Neighborhood Hits	376	Target Neighborhood Hits	193	Shared Neighborhood Hits	98
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

MDC1_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.056826 (rank : 343)
Query Neighborhood Hits	376	Target Neighborhood Hits	1446	Shared Neighborhood Hits	98
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MELPH_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.091582 (rank : 260)
Query Neighborhood Hits	376	Target Neighborhood Hits	145	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BV36, Q9HA71	Gene names	MLPH, SLAC2A
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Synaptotagmin-like protein 2a) (Slp homolog lacking C2 domains a).

MELPH_MOUSE
θ value	θ > 10 (rank : 418)	NC score	0.093040 (rank : 258)
Query Neighborhood Hits	376	Target Neighborhood Hits	112	Shared Neighborhood Hits	18
SwissProt Accessions	Q91V27, Q99N53	Gene names	Mlph, Ln, Slac2a
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Leaden protein) (Synaptotagmin-like protein 2a) (Slac2-a) (Slp homolog lacking C2 domains a).

MPP2_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.072887 (rank : 299)
Query Neighborhood Hits	376	Target Neighborhood Hits	173	Shared Neighborhood Hits	71
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

MPP2_MOUSE
θ value	θ > 10 (rank : 420)	NC score	0.073037 (rank : 298)
Query Neighborhood Hits	376	Target Neighborhood Hits	189	Shared Neighborhood Hits	74
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

MPP3_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.104702 (rank : 242)
Query Neighborhood Hits	376	Target Neighborhood Hits	171	Shared Neighborhood Hits	90
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

MPP3_MOUSE
θ value	θ > 10 (rank : 422)	NC score	0.104531 (rank : 244)
Query Neighborhood Hits	376	Target Neighborhood Hits	165	Shared Neighborhood Hits	90
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

MPP4_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.097851 (rank : 251)
Query Neighborhood Hits	376	Target Neighborhood Hits	188	Shared Neighborhood Hits	83
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

MPP6_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.075595 (rank : 294)
Query Neighborhood Hits	376	Target Neighborhood Hits	180	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

MPP6_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.075883 (rank : 293)
Query Neighborhood Hits	376	Target Neighborhood Hits	187	Shared Neighborhood Hits	76
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

NEB2_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.113644 (rank : 227)
Query Neighborhood Hits	376	Target Neighborhood Hits	883	Shared Neighborhood Hits	127
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	θ > 10 (rank : 427)	NC score	0.115019 (rank : 223)
Query Neighborhood Hits	376	Target Neighborhood Hits	889	Shared Neighborhood Hits	130
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NHERF_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.125871 (rank : 208)
Query Neighborhood Hits	376	Target Neighborhood Hits	190	Shared Neighborhood Hits	83
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NHERF_MOUSE
θ value	θ > 10 (rank : 429)	NC score	0.125510 (rank : 209)
Query Neighborhood Hits	376	Target Neighborhood Hits	195	Shared Neighborhood Hits	87
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NHRF2_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.130470 (rank : 198)
Query Neighborhood Hits	376	Target Neighborhood Hits	197	Shared Neighborhood Hits	88
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

NHRF2_MOUSE
θ value	θ > 10 (rank : 431)	NC score	0.131079 (rank : 196)
Query Neighborhood Hits	376	Target Neighborhood Hits	194	Shared Neighborhood Hits	89
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

NOLC1_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.050318 (rank : 371)
Query Neighborhood Hits	376	Target Neighborhood Hits	452	Shared Neighborhood Hits	31
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

NOS1_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.078350 (rank : 289)
Query Neighborhood Hits	376	Target Neighborhood Hits	155	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

OTOF_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.189574 (rank : 124)
Query Neighborhood Hits	376	Target Neighborhood Hits	168	Shared Neighborhood Hits	88
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

OTOF_MOUSE
θ value	θ > 10 (rank : 435)	NC score	0.189053 (rank : 127)
Query Neighborhood Hits	376	Target Neighborhood Hits	196	Shared Neighborhood Hits	94
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

PA24C_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.054336 (rank : 354)
Query Neighborhood Hits	376	Target Neighborhood Hits	13	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UP65, O75457, Q9UG68	Gene names	PLA2G4C
Domain Architecture
Description	Cytosolic phospholipase A2 gamma precursor (EC 3.1.1.4) (cPLA2-gamma) (Phospholipase A2 group IVC).

PDLI2_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.076263 (rank : 292)
Query Neighborhood Hits	376	Target Neighborhood Hits	245	Shared Neighborhood Hits	69
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

PDLI2_MOUSE
θ value	θ > 10 (rank : 438)	NC score	0.066810 (rank : 310)
Query Neighborhood Hits	376	Target Neighborhood Hits	220	Shared Neighborhood Hits	64
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

PDZ11_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.148289 (rank : 182)
Query Neighborhood Hits	376	Target Neighborhood Hits	160	Shared Neighborhood Hits	82
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZ11_MOUSE
θ value	θ > 10 (rank : 440)	NC score	0.149028 (rank : 181)
Query Neighborhood Hits	376	Target Neighborhood Hits	154	Shared Neighborhood Hits	78
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZD1_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.128270 (rank : 202)
Query Neighborhood Hits	376	Target Neighborhood Hits	190	Shared Neighborhood Hits	85
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

PDZD1_MOUSE
θ value	θ > 10 (rank : 442)	NC score	0.130845 (rank : 197)
Query Neighborhood Hits	376	Target Neighborhood Hits	191	Shared Neighborhood Hits	84
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

PDZD3_HUMAN
θ value	θ > 10 (rank : 443)	NC score	0.114485 (rank : 224)
Query Neighborhood Hits	376	Target Neighborhood Hits	180	Shared Neighborhood Hits	83
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

PDZD3_MOUSE
θ value	θ > 10 (rank : 444)	NC score	0.111122 (rank : 234)
Query Neighborhood Hits	376	Target Neighborhood Hits	171	Shared Neighborhood Hits	82
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

PDZD7_HUMAN
θ value	θ > 10 (rank : 445)	NC score	0.176668 (rank : 155)
Query Neighborhood Hits	376	Target Neighborhood Hits	181	Shared Neighborhood Hits	92
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

PDZD8_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.062924 (rank : 323)
Query Neighborhood Hits	376	Target Neighborhood Hits	185	Shared Neighborhood Hits	38
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PDZK4_HUMAN
θ value	θ > 10 (rank : 447)	NC score	0.094007 (rank : 255)
Query Neighborhood Hits	376	Target Neighborhood Hits	165	Shared Neighborhood Hits	83
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PI4KA_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.052537 (rank : 364)
Query Neighborhood Hits	376	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	P42356, Q7Z625, Q9UPG2	Gene names	PIK4CA, PIK4
Domain Architecture
Description	Phosphatidylinositol 4-kinase alpha (EC 2.7.1.67) (PI4-kinase alpha) (PtdIns-4-kinase alpha) (PI4K-alpha).

PK3C3_HUMAN
θ value	θ > 10 (rank : 449)	NC score	0.053064 (rank : 359)
Query Neighborhood Hits	376	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NEB9, Q15134	Gene names	PIK3C3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3) (Phosphatidylinositol 3-kinase p100 subunit).

PK3C3_MOUSE
θ value	θ > 10 (rank : 450)	NC score	0.052846 (rank : 361)
Query Neighborhood Hits	376	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PF93, Q8R3S8	Gene names	Pik3c3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3).

PK3CA_HUMAN
θ value	θ > 10 (rank : 451)	NC score	0.059616 (rank : 337)
Query Neighborhood Hits	376	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	P42336, Q99762	Gene names	PIK3CA
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

PK3CA_MOUSE
θ value	θ > 10 (rank : 452)	NC score	0.059668 (rank : 336)
Query Neighborhood Hits	376	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	P42337	Gene names	Pik3ca
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

PK3CB_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.056174 (rank : 349)
Query Neighborhood Hits	376	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	P42338	Gene names	PIK3CB
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

PK3CB_MOUSE
θ value	θ > 10 (rank : 454)	NC score	0.056219 (rank : 346)
Query Neighborhood Hits	376	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BTI9	Gene names	Pik3cb
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

PK3CD_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.056847 (rank : 342)
Query Neighborhood Hits	376	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	O00329, O15445	Gene names	PIK3CD
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

PK3CD_MOUSE
θ value	θ > 10 (rank : 456)	NC score	0.056955 (rank : 341)
Query Neighborhood Hits	376	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	O35904	Gene names	Pik3cd
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

PK3CG_HUMAN
θ value	θ > 10 (rank : 457)	NC score	0.061391 (rank : 332)
Query Neighborhood Hits	376	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	P48736, Q8IV23, Q9BZC8	Gene names	PIK3CG
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PK3CG_MOUSE
θ value	θ > 10 (rank : 458)	NC score	0.061267 (rank : 333)
Query Neighborhood Hits	376	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JHG7	Gene names	Pik3cg, Pi3kg1
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PLCD1_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.082578 (rank : 279)
Query Neighborhood Hits	376	Target Neighborhood Hits	93	Shared Neighborhood Hits	50
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

PLCD1_MOUSE
θ value	θ > 10 (rank : 460)	NC score	0.055584 (rank : 351)
Query Neighborhood Hits	376	Target Neighborhood Hits	106	Shared Neighborhood Hits	50
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

PSCBP_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.053520 (rank : 356)
Query Neighborhood Hits	376	Target Neighborhood Hits	123	Shared Neighborhood Hits	59
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

PSCBP_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.061748 (rank : 329)
Query Neighborhood Hits	376	Target Neighborhood Hits	118	Shared Neighborhood Hits	61
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

PZRN3_HUMAN
θ value	θ > 10 (rank : 463)	NC score	0.133310 (rank : 195)
Query Neighborhood Hits	376	Target Neighborhood Hits	461	Shared Neighborhood Hits	102
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	θ > 10 (rank : 464)	NC score	0.135043 (rank : 194)
Query Neighborhood Hits	376	Target Neighborhood Hits	447	Shared Neighborhood Hits	100
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

RASA2_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.224395 (rank : 96)
Query Neighborhood Hits	376	Target Neighborhood Hits	157	Shared Neighborhood Hits	75
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RASA2_MOUSE
θ value	θ > 10 (rank : 466)	NC score	0.224714 (rank : 95)
Query Neighborhood Hits	376	Target Neighborhood Hits	159	Shared Neighborhood Hits	75
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RASA3_MOUSE
θ value	θ > 10 (rank : 467)	NC score	0.179967 (rank : 147)
Query Neighborhood Hits	376	Target Neighborhood Hits	144	Shared Neighborhood Hits	70
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

RBBP6_HUMAN
θ value	θ > 10 (rank : 468)	NC score	0.072302 (rank : 301)
Query Neighborhood Hits	376	Target Neighborhood Hits	1135	Shared Neighborhood Hits	110
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	θ > 10 (rank : 469)	NC score	0.063671 (rank : 318)
Query Neighborhood Hits	376	Target Neighborhood Hits	1014	Shared Neighborhood Hits	100
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RFIP1_HUMAN
θ value	θ > 10 (rank : 470)	NC score	0.089805 (rank : 264)
Query Neighborhood Hits	376	Target Neighborhood Hits	236	Shared Neighborhood Hits	51
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

RFIP1_MOUSE
θ value	θ > 10 (rank : 471)	NC score	0.094208 (rank : 254)
Query Neighborhood Hits	376	Target Neighborhood Hits	152	Shared Neighborhood Hits	43
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

RHPN1_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.063365 (rank : 320)
Query Neighborhood Hits	376	Target Neighborhood Hits	158	Shared Neighborhood Hits	65
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

RHPN1_MOUSE
θ value	θ > 10 (rank : 473)	NC score	0.070989 (rank : 306)
Query Neighborhood Hits	376	Target Neighborhood Hits	154	Shared Neighborhood Hits	68
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

RPGF2_HUMAN
θ value	θ > 10 (rank : 474)	NC score	0.065675 (rank : 313)
Query Neighborhood Hits	376	Target Neighborhood Hits	242	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

RPGF6_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.079864 (rank : 286)
Query Neighborhood Hits	376	Target Neighborhood Hits	266	Shared Neighborhood Hits	89
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

SDCB2_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.077486 (rank : 290)
Query Neighborhood Hits	376	Target Neighborhood Hits	121	Shared Neighborhood Hits	61
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SDCB2_MOUSE
θ value	θ > 10 (rank : 477)	NC score	0.082510 (rank : 281)
Query Neighborhood Hits	376	Target Neighborhood Hits	118	Shared Neighborhood Hits	68
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SLC2B_HUMAN
θ value	θ > 10 (rank : 478)	NC score	0.064492 (rank : 317)
Query Neighborhood Hits	376	Target Neighborhood Hits	214	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

SYNP2_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.053941 (rank : 355)
Query Neighborhood Hits	376	Target Neighborhood Hits	323	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

SYP2L_HUMAN
θ value	θ > 10 (rank : 480)	NC score	0.073552 (rank : 296)
Query Neighborhood Hits	376	Target Neighborhood Hits	400	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

SYT13_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.352189 (rank : 61)
Query Neighborhood Hits	376	Target Neighborhood Hits	76	Shared Neighborhood Hits	66
SwissProt Accessions	Q7L8C5, Q9BQS3, Q9H041, Q9P2C0	Gene names	SYT13, KIAA1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

TAC2N_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.187871 (rank : 129)
Query Neighborhood Hits	376	Target Neighborhood Hits	47	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N9U0	Gene names	MTAC2D1, C14orf47
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

TAC2N_MOUSE
θ value	θ > 10 (rank : 483)	NC score	0.186162 (rank : 134)
Query Neighborhood Hits	376	Target Neighborhood Hits	43	Shared Neighborhood Hits	36
SwissProt Accessions	Q91XT6, Q9D4A0	Gene names	Mtac2d1
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

TARA_MOUSE
θ value	θ > 10 (rank : 484)	NC score	0.062466 (rank : 325)
Query Neighborhood Hits	376	Target Neighborhood Hits	1133	Shared Neighborhood Hits	91
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TGON2_HUMAN
θ value	θ > 10 (rank : 485)	NC score	0.064634 (rank : 316)
Query Neighborhood Hits	376	Target Neighborhood Hits	1037	Shared Neighborhood Hits	81
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TR150_MOUSE
θ value	θ > 10 (rank : 486)	NC score	0.050465 (rank : 369)
Query Neighborhood Hits	376	Target Neighborhood Hits	468	Shared Neighborhood Hits	69
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

TRIPC_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.057293 (rank : 339)
Query Neighborhood Hits	376	Target Neighborhood Hits	319	Shared Neighborhood Hits	53
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

TX1B3_HUMAN
θ value	θ > 10 (rank : 488)	NC score	0.130239 (rank : 199)
Query Neighborhood Hits	376	Target Neighborhood Hits	161	Shared Neighborhood Hits	84
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

TX1B3_MOUSE
θ value	θ > 10 (rank : 489)	NC score	0.127649 (rank : 203)
Query Neighborhood Hits	376	Target Neighborhood Hits	158	Shared Neighborhood Hits	83
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

TXND2_HUMAN
θ value	θ > 10 (rank : 490)	NC score	0.055487 (rank : 352)
Query Neighborhood Hits	376	Target Neighborhood Hits	793	Shared Neighborhood Hits	58
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

TXND2_MOUSE
θ value	θ > 10 (rank : 491)	NC score	0.061449 (rank : 331)
Query Neighborhood Hits	376	Target Neighborhood Hits	828	Shared Neighborhood Hits	86
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

WWC1_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.083460 (rank : 277)
Query Neighborhood Hits	376	Target Neighborhood Hits	290	Shared Neighborhood Hits	58
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

WWC1_MOUSE
θ value	θ > 10 (rank : 493)	NC score	0.104449 (rank : 245)
Query Neighborhood Hits	376	Target Neighborhood Hits	290	Shared Neighborhood Hits	61
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

WWP1_MOUSE
θ value	θ > 10 (rank : 494)	NC score	0.067671 (rank : 309)
Query Neighborhood Hits	376	Target Neighborhood Hits	138	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

WWP2_HUMAN
θ value	θ > 10 (rank : 495)	NC score	0.062710 (rank : 324)
Query Neighborhood Hits	376	Target Neighborhood Hits	177	Shared Neighborhood Hits	32
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

WWP2_MOUSE
θ value	θ > 10 (rank : 496)	NC score	0.061736 (rank : 330)
Query Neighborhood Hits	376	Target Neighborhood Hits	118	Shared Neighborhood Hits	25
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

YAP1_MOUSE
θ value	θ > 10 (rank : 497)	NC score	0.055814 (rank : 350)
Query Neighborhood Hits	376	Target Neighborhood Hits	96	Shared Neighborhood Hits	25
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

YTDC1_HUMAN
θ value	θ > 10 (rank : 498)	NC score	0.058577 (rank : 338)
Query Neighborhood Hits	376	Target Neighborhood Hits	458	Shared Neighborhood Hits	68
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

Hits sorted by NC score

RIMS2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	376	Target Neighborhood Hits	376	Shared Neighborhood Hits	376
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

RIMS2_HUMAN
NC score	0.987681 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	376	Target Neighborhood Hits	342	Shared Neighborhood Hits	290
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS1_HUMAN
NC score	0.940040 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	376	Target Neighborhood Hits	437	Shared Neighborhood Hits	230
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

RIMS4_MOUSE
NC score	0.883349 (rank : 4)	θ value	1.76739e-88 (rank : 7)
Query Neighborhood Hits	376	Target Neighborhood Hits	76	Shared Neighborhood Hits	71
SwissProt Accessions	P60191	Gene names	Rims4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

RIMS4_HUMAN
NC score	0.883045 (rank : 5)	θ value	6.07444e-89 (rank : 6)
Query Neighborhood Hits	376	Target Neighborhood Hits	76	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H426, Q5JWT7	Gene names	RIMS4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

RIMS3_HUMAN
NC score	0.876783 (rank : 6)	θ value	2.5344e-111 (rank : 4)
Query Neighborhood Hits	376	Target Neighborhood Hits	66	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UJD0, Q92511	Gene names	RIMS3, KIAA0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RIMS3_MOUSE
NC score	0.871114 (rank : 7)	θ value	5.64607e-111 (rank : 5)
Query Neighborhood Hits	376	Target Neighborhood Hits	67	Shared Neighborhood Hits	66
SwissProt Accessions	Q80U57	Gene names	Rims3, Kiaa0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

DOC2A_MOUSE
NC score	0.593071 (rank : 8)	θ value	2.98157e-11 (rank : 21)
Query Neighborhood Hits	376	Target Neighborhood Hits	140	Shared Neighborhood Hits	105
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

DOC2A_HUMAN
NC score	0.590733 (rank : 9)	θ value	2.28291e-11 (rank : 20)
Query Neighborhood Hits	376	Target Neighborhood Hits	144	Shared Neighborhood Hits	106
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

SYTL3_MOUSE
NC score	0.587927 (rank : 10)	θ value	2.79066e-09 (rank : 39)
Query Neighborhood Hits	376	Target Neighborhood Hits	110	Shared Neighborhood Hits	83
SwissProt Accessions	Q99N48, Q8C506, Q99N47, Q99N49, Q99N54, Q99N79	Gene names	Sytl3, Slp3
Domain Architecture
Description	Synaptotagmin-like protein 3 (Exophilin-6).

SYTL4_HUMAN
NC score	0.584804 (rank : 11)	θ value	6.00763e-12 (rank : 16)
Query Neighborhood Hits	376	Target Neighborhood Hits	138	Shared Neighborhood Hits	93
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL1_HUMAN
NC score	0.583807 (rank : 12)	θ value	1.25267e-09 (rank : 38)
Query Neighborhood Hits	376	Target Neighborhood Hits	227	Shared Neighborhood Hits	105
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

DOC2B_HUMAN
NC score	0.582756 (rank : 13)	θ value	1.2105e-12 (rank : 10)
Query Neighborhood Hits	376	Target Neighborhood Hits	150	Shared Neighborhood Hits	107
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

SYTL4_MOUSE
NC score	0.581987 (rank : 14)	θ value	3.52202e-12 (rank : 13)
Query Neighborhood Hits	376	Target Neighborhood Hits	137	Shared Neighborhood Hits	97
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

RP3A_HUMAN
NC score	0.581840 (rank : 15)	θ value	4.59992e-12 (rank : 15)
Query Neighborhood Hits	376	Target Neighborhood Hits	305	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

DOC2B_MOUSE
NC score	0.580655 (rank : 16)	θ value	1.2105e-12 (rank : 11)
Query Neighborhood Hits	376	Target Neighborhood Hits	169	Shared Neighborhood Hits	107
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

SYTL5_HUMAN
NC score	0.579545 (rank : 17)	θ value	3.89403e-11 (rank : 24)
Query Neighborhood Hits	376	Target Neighborhood Hits	237	Shared Neighborhood Hits	120
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SYT7_MOUSE
NC score	0.572672 (rank : 18)	θ value	1.25267e-09 (rank : 37)
Query Neighborhood Hits	376	Target Neighborhood Hits	137	Shared Neighborhood Hits	105
SwissProt Accessions	Q9R0N7	Gene names	Syt7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

RP3A_MOUSE
NC score	0.571694 (rank : 19)	θ value	1.02475e-11 (rank : 18)
Query Neighborhood Hits	376	Target Neighborhood Hits	510	Shared Neighborhood Hits	125
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SYTL5_MOUSE
NC score	0.568276 (rank : 20)	θ value	9.92553e-07 (rank : 52)
Query Neighborhood Hits	376	Target Neighborhood Hits	154	Shared Neighborhood Hits	101
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SYT3_HUMAN
NC score	0.563827 (rank : 21)	θ value	1.02475e-11 (rank : 19)
Query Neighborhood Hits	376	Target Neighborhood Hits	145	Shared Neighborhood Hits	103
SwissProt Accessions	Q9BQG1, Q8N5Z1, Q8N640	Gene names	SYT3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT7_HUMAN
NC score	0.559821 (rank : 22)	θ value	5.26297e-08 (rank : 45)
Query Neighborhood Hits	376	Target Neighborhood Hits	137	Shared Neighborhood Hits	105
SwissProt Accessions	O43581	Gene names	SYT7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

SYT3_MOUSE
NC score	0.559361 (rank : 23)	θ value	2.52405e-10 (rank : 30)
Query Neighborhood Hits	376	Target Neighborhood Hits	147	Shared Neighborhood Hits	102
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYTL1_MOUSE
NC score	0.553780 (rank : 24)	θ value	1.06045e-08 (rank : 43)
Query Neighborhood Hits	376	Target Neighborhood Hits	314	Shared Neighborhood Hits	99
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

SYT6_MOUSE
NC score	0.549016 (rank : 25)	θ value	8.67504e-11 (rank : 26)
Query Neighborhood Hits	376	Target Neighborhood Hits	132	Shared Neighborhood Hits	105
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

FA62A_HUMAN
NC score	0.549000 (rank : 26)	θ value	4.59992e-12 (rank : 14)
Query Neighborhood Hits	376	Target Neighborhood Hits	168	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

FA62A_MOUSE
NC score	0.548769 (rank : 27)	θ value	1.06045e-08 (rank : 42)
Query Neighborhood Hits	376	Target Neighborhood Hits	155	Shared Neighborhood Hits	107
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

SYT2_MOUSE
NC score	0.548400 (rank : 28)	θ value	5.62301e-10 (rank : 33)
Query Neighborhood Hits	376	Target Neighborhood Hits	143	Shared Neighborhood Hits	106
SwissProt Accessions	P46097, Q8R0E1	Gene names	Syt2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT2_HUMAN
NC score	0.548052 (rank : 29)	θ value	7.34386e-10 (rank : 36)
Query Neighborhood Hits	376	Target Neighborhood Hits	142	Shared Neighborhood Hits	106
SwissProt Accessions	Q8N9I0, Q496K5, Q8NBE5	Gene names	SYT2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT6_HUMAN
NC score	0.548010 (rank : 30)	θ value	1.47974e-10 (rank : 27)
Query Neighborhood Hits	376	Target Neighborhood Hits	138	Shared Neighborhood Hits	108
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT9_MOUSE
NC score	0.547728 (rank : 31)	θ value	2.98157e-11 (rank : 23)
Query Neighborhood Hits	376	Target Neighborhood Hits	148	Shared Neighborhood Hits	106
SwissProt Accessions	Q9R0N9, Q8C280	Gene names	Syt9, Syt5
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V).

SYTL2_HUMAN
NC score	0.544893 (rank : 32)	θ value	5.81887e-07 (rank : 50)
Query Neighborhood Hits	376	Target Neighborhood Hits	248	Shared Neighborhood Hits	110
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYT9_HUMAN
NC score	0.544775 (rank : 33)	θ value	4.30538e-10 (rank : 32)
Query Neighborhood Hits	376	Target Neighborhood Hits	144	Shared Neighborhood Hits	105
SwissProt Accessions	Q86SS6	Gene names	SYT9
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX).

SYT10_HUMAN
NC score	0.543164 (rank : 34)	θ value	2.52405e-10 (rank : 29)
Query Neighborhood Hits	376	Target Neighborhood Hits	134	Shared Neighborhood Hits	105
SwissProt Accessions	Q6XYQ8	Gene names	SYT10
Domain Architecture	No domain graphic available
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT10_MOUSE
NC score	0.541167 (rank : 35)	θ value	7.34386e-10 (rank : 35)
Query Neighborhood Hits	376	Target Neighborhood Hits	133	Shared Neighborhood Hits	106
SwissProt Accessions	Q9R0N4	Gene names	Syt10
Domain Architecture
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYTL2_MOUSE
NC score	0.540532 (rank : 36)	θ value	4.45536e-07 (rank : 48)
Query Neighborhood Hits	376	Target Neighborhood Hits	253	Shared Neighborhood Hits	111
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYT1_HUMAN
NC score	0.538454 (rank : 37)	θ value	6.21693e-09 (rank : 40)
Query Neighborhood Hits	376	Target Neighborhood Hits	150	Shared Neighborhood Hits	105
SwissProt Accessions	P21579	Gene names	SYT1, SYT
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT1_MOUSE
NC score	0.538442 (rank : 38)	θ value	6.21693e-09 (rank : 41)
Query Neighborhood Hits	376	Target Neighborhood Hits	150	Shared Neighborhood Hits	105
SwissProt Accessions	P46096	Gene names	Syt1
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

DOC2G_MOUSE
NC score	0.537926 (rank : 39)	θ value	8.40245e-06 (rank : 61)
Query Neighborhood Hits	376	Target Neighborhood Hits	125	Shared Neighborhood Hits	94
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

SYT5_HUMAN
NC score	0.530103 (rank : 40)	θ value	5.81887e-07 (rank : 49)
Query Neighborhood Hits	376	Target Neighborhood Hits	138	Shared Neighborhood Hits	107
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

SYT5_MOUSE
NC score	0.523122 (rank : 41)	θ value	4.1701e-05 (rank : 66)
Query Neighborhood Hits	376	Target Neighborhood Hits	140	Shared Neighborhood Hits	107
SwissProt Accessions	Q9R0N5	Gene names	Syt5, Syt9
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin IX).

PCLO_MOUSE
NC score	0.520817 (rank : 42)	θ value	2.27234e-27 (rank : 8)
Query Neighborhood Hits	376	Target Neighborhood Hits	2275	Shared Neighborhood Hits	264
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SYT4_HUMAN
NC score	0.518831 (rank : 43)	θ value	1.69304e-06 (rank : 53)
Query Neighborhood Hits	376	Target Neighborhood Hits	121	Shared Neighborhood Hits	100
SwissProt Accessions	Q9H2B2, Q9P2K4	Gene names	SYT4, KIAA1342
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

SYT4_MOUSE
NC score	0.512523 (rank : 44)	θ value	4.92598e-06 (rank : 60)
Query Neighborhood Hits	376	Target Neighborhood Hits	123	Shared Neighborhood Hits	98
SwissProt Accessions	P40749, Q3UFC1, Q8BGH3, Q8BRL6	Gene names	Syt4, Syt3
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

SYT11_MOUSE
NC score	0.512379 (rank : 45)	θ value	2.88788e-06 (rank : 56)
Query Neighborhood Hits	376	Target Neighborhood Hits	116	Shared Neighborhood Hits	98
SwissProt Accessions	Q9R0N3	Gene names	Syt11
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT11_HUMAN
NC score	0.511162 (rank : 46)	θ value	3.77169e-06 (rank : 58)
Query Neighborhood Hits	376	Target Neighborhood Hits	113	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BT88, Q14998, Q68CT5, Q8IXU3, Q96SU2	Gene names	SYT11, KIAA0080
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT12_HUMAN
NC score	0.506828 (rank : 47)	θ value	0.000158464 (rank : 73)
Query Neighborhood Hits	376	Target Neighborhood Hits	100	Shared Neighborhood Hits	80
SwissProt Accessions	Q8IV01	Gene names	SYT12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT12_MOUSE
NC score	0.506307 (rank : 48)	θ value	0.000461057 (rank : 83)
Query Neighborhood Hits	376	Target Neighborhood Hits	102	Shared Neighborhood Hits	83
SwissProt Accessions	Q920N7	Gene names	Syt12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

PCLO_HUMAN
NC score	0.493378 (rank : 49)	θ value	3.17815e-21 (rank : 9)
Query Neighborhood Hits	376	Target Neighborhood Hits	2046	Shared Neighborhood Hits	186
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SYT15_HUMAN
NC score	0.487316 (rank : 50)	θ value	1.87187e-05 (rank : 65)
Query Neighborhood Hits	376	Target Neighborhood Hits	112	Shared Neighborhood Hits	91
SwissProt Accessions	Q9BQS2, Q7Z439, Q7Z440	Gene names	SYT15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV) (Chr10Syt).

SYT8_MOUSE
NC score	0.472101 (rank : 51)	θ value	0.0148317 (rank : 119)
Query Neighborhood Hits	376	Target Neighborhood Hits	94	Shared Neighborhood Hits	78
SwissProt Accessions	Q9R0N6, Q64366, Q8C6E7	Gene names	Syt8
Domain Architecture
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

SYT15_MOUSE
NC score	0.448014 (rank : 52)	θ value	0.0961366 (rank : 153)
Query Neighborhood Hits	376	Target Neighborhood Hits	100	Shared Neighborhood Hits	87
SwissProt Accessions	Q8C6N3, Q7TN81, Q7TN82, Q8C999	Gene names	Syt15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV).

P3C2B_HUMAN
NC score	0.436756 (rank : 53)	θ value	1.2105e-12 (rank : 12)
Query Neighborhood Hits	376	Target Neighborhood Hits	148	Shared Neighborhood Hits	82
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

RASL2_HUMAN
NC score	0.432253 (rank : 54)	θ value	7.59969e-07 (rank : 51)
Query Neighborhood Hits	376	Target Neighborhood Hits	161	Shared Neighborhood Hits	97
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

P3C2A_HUMAN
NC score	0.381292 (rank : 55)	θ value	3.08544e-08 (rank : 44)
Query Neighborhood Hits	376	Target Neighborhood Hits	188	Shared Neighborhood Hits	75
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

P3C2A_MOUSE
NC score	0.376674 (rank : 56)	θ value	6.87365e-08 (rank : 46)
Query Neighborhood Hits	376	Target Neighborhood Hits	181	Shared Neighborhood Hits	75
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

UN13D_HUMAN
NC score	0.361029 (rank : 57)	θ value	0.00509761 (rank : 102)
Query Neighborhood Hits	376	Target Neighborhood Hits	117	Shared Neighborhood Hits	86
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

SYT13_MOUSE
NC score	0.355736 (rank : 58)	θ value	6.88961 (rank : 345)
Query Neighborhood Hits	376	Target Neighborhood Hits	69	Shared Neighborhood Hits	65
SwissProt Accessions	Q9EQT6, Q6ZPR2, Q8BRK6	Gene names	Syt13, Kiaa1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

SYT14_MOUSE
NC score	0.355148 (rank : 59)	θ value	2.36792 (rank : 276)
Query Neighborhood Hits	376	Target Neighborhood Hits	82	Shared Neighborhood Hits	62
SwissProt Accessions	Q7TN84	Gene names	Syt14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

SYT14_HUMAN
NC score	0.353923 (rank : 60)	θ value	1.38821 (rank : 248)
Query Neighborhood Hits	376	Target Neighborhood Hits	81	Shared Neighborhood Hits	60
SwissProt Accessions	Q8NB59, Q5THX7, Q707N3, Q707N4, Q707N5, Q707N6, Q707N7	Gene names	SYT14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

SYT13_HUMAN
NC score	0.352189 (rank : 61)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	376	Target Neighborhood Hits	76	Shared Neighborhood Hits	66
SwissProt Accessions	Q7L8C5, Q9BQS3, Q9H041, Q9P2C0	Gene names	SYT13, KIAA1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

RASL1_HUMAN
NC score	0.336792 (rank : 62)	θ value	0.00102713 (rank : 85)
Query Neighborhood Hits	376	Target Neighborhood Hits	142	Shared Neighborhood Hits	86
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

RASL1_MOUSE
NC score	0.323008 (rank : 63)	θ value	0.00298849 (rank : 94)
Query Neighborhood Hits	376	Target Neighborhood Hits	148	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

UN13B_MOUSE
NC score	0.320046 (rank : 64)	θ value	3.77169e-06 (rank : 59)
Query Neighborhood Hits	376	Target Neighborhood Hits	210	Shared Neighborhood Hits	90
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13B_HUMAN
NC score	0.318675 (rank : 65)	θ value	2.88788e-06 (rank : 57)
Query Neighborhood Hits	376	Target Neighborhood Hits	217	Shared Neighborhood Hits	96
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13A_HUMAN
NC score	0.317916 (rank : 66)	θ value	8.40245e-06 (rank : 62)
Query Neighborhood Hits	376	Target Neighborhood Hits	285	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

BAIP3_HUMAN
NC score	0.316694 (rank : 67)	θ value	1.81305 (rank : 250)
Query Neighborhood Hits	376	Target Neighborhood Hits	108	Shared Neighborhood Hits	80
SwissProt Accessions	O94812, O94839, Q2M226, Q658J2, Q76N05, Q96RZ3, Q9UJK1	Gene names	BAIAP3, KIAA0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

BAIP3_MOUSE
NC score	0.308185 (rank : 68)	θ value	5.27518 (rank : 308)
Query Neighborhood Hits	376	Target Neighborhood Hits	112	Shared Neighborhood Hits	83
SwissProt Accessions	Q80TT2, Q6RUT4	Gene names	Baiap3, Gm937, Kiaa0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

NED4L_HUMAN
NC score	0.283437 (rank : 69)	θ value	0.00020696 (rank : 74)
Query Neighborhood Hits	376	Target Neighborhood Hits	238	Shared Neighborhood Hits	114
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_MOUSE
NC score	0.278722 (rank : 70)	θ value	0.00020696 (rank : 75)
Query Neighborhood Hits	376	Target Neighborhood Hits	231	Shared Neighborhood Hits	113
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

PA24D_MOUSE
NC score	0.275855 (rank : 71)	θ value	0.0148317 (rank : 116)
Query Neighborhood Hits	376	Target Neighborhood Hits	100	Shared Neighborhood Hits	82
SwissProt Accessions	Q50L43, Q3TJC5	Gene names	Pla2g4d
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

K0528_MOUSE
NC score	0.270947 (rank : 72)	θ value	8.99809 (rank : 357)
Query Neighborhood Hits	376	Target Neighborhood Hits	102	Shared Neighborhood Hits	78
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

K0528_HUMAN
NC score	0.269648 (rank : 73)	θ value	8.99809 (rank : 356)
Query Neighborhood Hits	376	Target Neighborhood Hits	96	Shared Neighborhood Hits	76
SwissProt Accessions	Q86YS7, O60280, Q7Z619, Q86SU3	Gene names	KIAA0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

NEDD4_HUMAN
NC score	0.259694 (rank : 74)	θ value	0.00298849 (rank : 93)
Query Neighborhood Hits	376	Target Neighborhood Hits	214	Shared Neighborhood Hits	114
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

PDZD2_HUMAN
NC score	0.255926 (rank : 75)	θ value	1.43324e-05 (rank : 64)
Query Neighborhood Hits	376	Target Neighborhood Hits	772	Shared Neighborhood Hits	135
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

IL16_HUMAN
NC score	0.248176 (rank : 76)	θ value	7.1131e-05 (rank : 68)
Query Neighborhood Hits	376	Target Neighborhood Hits	207	Shared Neighborhood Hits	93
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

NEDD4_MOUSE
NC score	0.244804 (rank : 77)	θ value	0.0193708 (rank : 121)
Query Neighborhood Hits	376	Target Neighborhood Hits	212	Shared Neighborhood Hits	113
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

MPDZ_HUMAN
NC score	0.243629 (rank : 78)	θ value	1.43324e-05 (rank : 63)
Query Neighborhood Hits	376	Target Neighborhood Hits	261	Shared Neighborhood Hits	105
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

DYSF_HUMAN
NC score	0.242389 (rank : 79)	θ value	0.813845 (rank : 223)
Query Neighborhood Hits	376	Target Neighborhood Hits	170	Shared Neighborhood Hits	106
SwissProt Accessions	O75923, O75696, Q9UEN7	Gene names	DYSF, FER1L1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

PA24D_HUMAN
NC score	0.242258 (rank : 80)	θ value	0.365318 (rank : 200)
Query Neighborhood Hits	376	Target Neighborhood Hits	97	Shared Neighborhood Hits	81
SwissProt Accessions	Q86XP0, Q8N176	Gene names	PLA2G4D
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

MPDZ_MOUSE
NC score	0.241684 (rank : 81)	θ value	5.44631e-05 (rank : 67)
Query Neighborhood Hits	376	Target Neighborhood Hits	298	Shared Neighborhood Hits	108
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

IL16_MOUSE
NC score	0.237412 (rank : 82)	θ value	0.00175202 (rank : 87)
Query Neighborhood Hits	376	Target Neighborhood Hits	189	Shared Neighborhood Hits	94
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

USH1C_HUMAN
NC score	0.236171 (rank : 83)	θ value	0.000270298 (rank : 77)
Query Neighborhood Hits	376	Target Neighborhood Hits	327	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

INADL_HUMAN
NC score	0.235114 (rank : 84)	θ value	0.00035302 (rank : 79)
Query Neighborhood Hits	376	Target Neighborhood Hits	260	Shared Neighborhood Hits	103
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

INADL_MOUSE
NC score	0.234865 (rank : 85)	θ value	0.00035302 (rank : 80)
Query Neighborhood Hits	376	Target Neighborhood Hits	290	Shared Neighborhood Hits	106
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

RASA3_HUMAN
NC score	0.233808 (rank : 86)	θ value	0.279714 (rank : 189)
Query Neighborhood Hits	376	Target Neighborhood Hits	166	Shared Neighborhood Hits	78
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

DYSF_MOUSE
NC score	0.230453 (rank : 87)	θ value	0.813845 (rank : 224)
Query Neighborhood Hits	376	Target Neighborhood Hits	162	Shared Neighborhood Hits	101
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

PA24B_MOUSE
NC score	0.230393 (rank : 88)	θ value	0.0563607 (rank : 141)
Query Neighborhood Hits	376	Target Neighborhood Hits	102	Shared Neighborhood Hits	77
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

PARD3_HUMAN
NC score	0.229245 (rank : 89)	θ value	0.0113563 (rank : 110)
Query Neighborhood Hits	376	Target Neighborhood Hits	312	Shared Neighborhood Hits	127
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

P3C2G_MOUSE
NC score	0.228661 (rank : 90)	θ value	0.000461057 (rank : 81)
Query Neighborhood Hits	376	Target Neighborhood Hits	113	Shared Neighborhood Hits	65
SwissProt Accessions	O70167, O70168	Gene names	Pik3c2g
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

MYOF_HUMAN
NC score	0.228369 (rank : 91)	θ value	1.38821 (rank : 246)
Query Neighborhood Hits	376	Target Neighborhood Hits	147	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NZM1, Q9HBU3, Q9NZM0, Q9ULL3, Q9Y4U4	Gene names	FER1L3, KIAA1207, MYOF
Domain Architecture
Description	Myoferlin (Fer-1-like protein 3).

PARD3_MOUSE
NC score	0.227800 (rank : 92)	θ value	0.00869519 (rank : 105)
Query Neighborhood Hits	376	Target Neighborhood Hits	290	Shared Neighborhood Hits	126
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

USH1C_MOUSE
NC score	0.227272 (rank : 93)	θ value	0.000270298 (rank : 78)
Query Neighborhood Hits	376	Target Neighborhood Hits	557	Shared Neighborhood Hits	126
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

PAR3L_HUMAN
NC score	0.226313 (rank : 94)	θ value	0.00869519 (rank : 104)
Query Neighborhood Hits	376	Target Neighborhood Hits	297	Shared Neighborhood Hits	105
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

RASA2_MOUSE
NC score	0.224714 (rank : 95)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	376	Target Neighborhood Hits	159	Shared Neighborhood Hits	75
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RASA2_HUMAN
NC score	0.224395 (rank : 96)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	376	Target Neighborhood Hits	157	Shared Neighborhood Hits	75
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

WHRN_MOUSE
NC score	0.219333 (rank : 97)	θ value	0.00134147 (rank : 86)
Query Neighborhood Hits	376	Target Neighborhood Hits	412	Shared Neighborhood Hits	116
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

LIN7B_HUMAN
NC score	0.217505 (rank : 98)	θ value	0.00298849 (rank : 91)
Query Neighborhood Hits	376	Target Neighborhood Hits	200	Shared Neighborhood Hits	100
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

LIN7B_MOUSE
NC score	0.216671 (rank : 99)	θ value	0.00390308 (rank : 98)
Query Neighborhood Hits	376	Target Neighborhood Hits	200	Shared Neighborhood Hits	100
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

WHRN_HUMAN
NC score	0.214324 (rank : 100)	θ value	0.0113563 (rank : 112)
Query Neighborhood Hits	376	Target Neighborhood Hits	325	Shared Neighborhood Hits	107
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

RFIP2_HUMAN
NC score	0.213126 (rank : 101)	θ value	2.36792 (rank : 273)
Query Neighborhood Hits	376	Target Neighborhood Hits	97	Shared Neighborhood Hits	70
SwissProt Accessions	Q7L804, Q9Y2F0	Gene names	RAB11FIP2, KIAA0941
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11).

LIN7C_HUMAN
NC score	0.212437 (rank : 102)	θ value	0.0148317 (rank : 113)
Query Neighborhood Hits	376	Target Neighborhood Hits	198	Shared Neighborhood Hits	100
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
NC score	0.212437 (rank : 103)	θ value	0.0148317 (rank : 114)
Query Neighborhood Hits	376	Target Neighborhood Hits	198	Shared Neighborhood Hits	100
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

RGS3_HUMAN
NC score	0.211980 (rank : 104)	θ value	2.88788e-06 (rank : 55)
Query Neighborhood Hits	376	Target Neighborhood Hits	1375	Shared Neighborhood Hits	145
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

PA24B_HUMAN
NC score	0.209546 (rank : 105)	θ value	0.00390308 (rank : 99)
Query Neighborhood Hits	376	Target Neighborhood Hits	89	Shared Neighborhood Hits	68
SwissProt Accessions	O95712, Q59GF9, Q8TB10, Q9UKV7	Gene names	PLA2G4B
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

PA24E_MOUSE
NC score	0.207166 (rank : 106)	θ value	0.163984 (rank : 168)
Query Neighborhood Hits	376	Target Neighborhood Hits	95	Shared Neighborhood Hits	77
SwissProt Accessions	Q50L42, Q8BX44	Gene names	Pla2g4e
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

LNX2_HUMAN
NC score	0.205865 (rank : 107)	θ value	0.00298849 (rank : 92)
Query Neighborhood Hits	376	Target Neighborhood Hits	389	Shared Neighborhood Hits	102
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

P3C2G_HUMAN
NC score	0.204938 (rank : 108)	θ value	0.000158464 (rank : 72)
Query Neighborhood Hits	376	Target Neighborhood Hits	92	Shared Neighborhood Hits	48
SwissProt Accessions	O75747	Gene names	PIK3C2G
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

LNX2_MOUSE
NC score	0.204557 (rank : 109)	θ value	0.0148317 (rank : 115)
Query Neighborhood Hits	376	Target Neighborhood Hits	407	Shared Neighborhood Hits	103
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

ZO3_MOUSE
NC score	0.203792 (rank : 110)	θ value	9.29e-05 (rank : 71)
Query Neighborhood Hits	376	Target Neighborhood Hits	224	Shared Neighborhood Hits	101
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

LNX1_MOUSE
NC score	0.202231 (rank : 111)	θ value	0.0113563 (rank : 108)
Query Neighborhood Hits	376	Target Neighborhood Hits	377	Shared Neighborhood Hits	106
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

SYJ2B_HUMAN
NC score	0.201640 (rank : 112)	θ value	4.03905 (rank : 305)
Query Neighborhood Hits	376	Target Neighborhood Hits	162	Shared Neighborhood Hits	97
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

SNTA1_HUMAN
NC score	0.200558 (rank : 113)	θ value	0.0113563 (rank : 111)
Query Neighborhood Hits	376	Target Neighborhood Hits	186	Shared Neighborhood Hits	94
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

MAGI1_MOUSE
NC score	0.198530 (rank : 114)	θ value	0.62314 (rank : 215)
Query Neighborhood Hits	376	Target Neighborhood Hits	403	Shared Neighborhood Hits	143
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

MAGI1_HUMAN
NC score	0.196476 (rank : 115)	θ value	0.0736092 (rank : 147)
Query Neighborhood Hits	376	Target Neighborhood Hits	388	Shared Neighborhood Hits	141
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

DLG2_MOUSE
NC score	0.195465 (rank : 116)	θ value	0.00665767 (rank : 103)
Query Neighborhood Hits	376	Target Neighborhood Hits	271	Shared Neighborhood Hits	104
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

SNTG2_HUMAN
NC score	0.195275 (rank : 117)	θ value	0.0431538 (rank : 139)
Query Neighborhood Hits	376	Target Neighborhood Hits	191	Shared Neighborhood Hits	99
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

PA24A_MOUSE
NC score	0.194755 (rank : 118)	θ value	0.365318 (rank : 199)
Query Neighborhood Hits	376	Target Neighborhood Hits	100	Shared Neighborhood Hits	78
SwissProt Accessions	P47713	Gene names	Pla2g4a, Cpla2, Pla2g4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

DLG2_HUMAN
NC score	0.194567 (rank : 119)	θ value	0.00390308 (rank : 96)
Query Neighborhood Hits	376	Target Neighborhood Hits	279	Shared Neighborhood Hits	104
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

GRIP2_HUMAN
NC score	0.192009 (rank : 120)	θ value	1.06291 (rank : 233)
Query Neighborhood Hits	376	Target Neighborhood Hits	256	Shared Neighborhood Hits	106
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

DLG4_MOUSE
NC score	0.191968 (rank : 121)	θ value	0.0252991 (rank : 123)
Query Neighborhood Hits	376	Target Neighborhood Hits	282	Shared Neighborhood Hits	100
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

GRIP1_HUMAN
NC score	0.191807 (rank : 122)	θ value	0.21417 (rank : 176)
Query Neighborhood Hits	376	Target Neighborhood Hits	231	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

DLG4_HUMAN
NC score	0.191600 (rank : 123)	θ value	0.0252991 (rank : 122)
Query Neighborhood Hits	376	Target Neighborhood Hits	286	Shared Neighborhood Hits	99
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

OTOF_HUMAN
NC score	0.189574 (rank : 124)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	376	Target Neighborhood Hits	168	Shared Neighborhood Hits	88
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

MAGI2_MOUSE
NC score	0.189343 (rank : 125)	θ value	0.365318 (rank : 197)
Query Neighborhood Hits	376	Target Neighborhood Hits	370	Shared Neighborhood Hits	122
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

PA24E_HUMAN
NC score	0.189157 (rank : 126)	θ value	1.06291 (rank : 237)
Query Neighborhood Hits	376	Target Neighborhood Hits	89	Shared Neighborhood Hits	72
SwissProt Accessions	Q3MJ16, Q6ZSC0	Gene names	PLA2G4E
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

OTOF_MOUSE
NC score	0.189053 (rank : 127)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	376	Target Neighborhood Hits	196	Shared Neighborhood Hits	94
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

GRIP1_MOUSE
NC score	0.188529 (rank : 128)	θ value	0.62314 (rank : 213)
Query Neighborhood Hits	376	Target Neighborhood Hits	241	Shared Neighborhood Hits	109
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

TAC2N_HUMAN
NC score	0.187871 (rank : 129)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	376	Target Neighborhood Hits	47	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N9U0	Gene names	MTAC2D1, C14orf47
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

PA24A_HUMAN
NC score	0.187094 (rank : 130)	θ value	0.365318 (rank : 198)
Query Neighborhood Hits	376	Target Neighborhood Hits	88	Shared Neighborhood Hits	77
SwissProt Accessions	P47712	Gene names	PLA2G4A, CPLA2, PLA2G4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

SNTB2_HUMAN
NC score	0.186837 (rank : 131)	θ value	0.125558 (rank : 160)
Query Neighborhood Hits	376	Target Neighborhood Hits	180	Shared Neighborhood Hits	92
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTA1_MOUSE
NC score	0.186583 (rank : 132)	θ value	0.0563607 (rank : 142)
Query Neighborhood Hits	376	Target Neighborhood Hits	170	Shared Neighborhood Hits	91
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

SNTB2_MOUSE
NC score	0.186163 (rank : 133)	θ value	0.125558 (rank : 161)
Query Neighborhood Hits	376	Target Neighborhood Hits	181	Shared Neighborhood Hits	92
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

TAC2N_MOUSE
NC score	0.186162 (rank : 134)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	376	Target Neighborhood Hits	43	Shared Neighborhood Hits	36
SwissProt Accessions	Q91XT6, Q9D4A0	Gene names	Mtac2d1
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

MAGI2_HUMAN
NC score	0.185734 (rank : 135)	θ value	0.365318 (rank : 196)
Query Neighborhood Hits	376	Target Neighborhood Hits	373	Shared Neighborhood Hits	118
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

LNX1_HUMAN
NC score	0.185654 (rank : 136)	θ value	1.81305 (rank : 256)
Query Neighborhood Hits	376	Target Neighborhood Hits	379	Shared Neighborhood Hits	104
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

DLG1_MOUSE
NC score	0.184368 (rank : 137)	θ value	0.21417 (rank : 175)
Query Neighborhood Hits	376	Target Neighborhood Hits	285	Shared Neighborhood Hits	102
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

PAR6G_MOUSE
NC score	0.184266 (rank : 138)	θ value	0.00509761 (rank : 100)
Query Neighborhood Hits	376	Target Neighborhood Hits	121	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

DLG1_HUMAN
NC score	0.184095 (rank : 139)	θ value	0.279714 (rank : 185)
Query Neighborhood Hits	376	Target Neighborhood Hits	290	Shared Neighborhood Hits	103
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

SNTB1_MOUSE
NC score	0.183606 (rank : 140)	θ value	0.0431538 (rank : 138)
Query Neighborhood Hits	376	Target Neighborhood Hits	160	Shared Neighborhood Hits	87
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

ZO3_HUMAN
NC score	0.183413 (rank : 141)	θ value	0.00869519 (rank : 107)
Query Neighborhood Hits	376	Target Neighborhood Hits	219	Shared Neighborhood Hits	96
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

SNTG2_MOUSE
NC score	0.181501 (rank : 142)	θ value	0.163984 (rank : 171)
Query Neighborhood Hits	376	Target Neighborhood Hits	176	Shared Neighborhood Hits	94
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

DLG3_MOUSE
NC score	0.180993 (rank : 143)	θ value	2.36792 (rank : 264)
Query Neighborhood Hits	376	Target Neighborhood Hits	274	Shared Neighborhood Hits	104
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

PAR6A_HUMAN
NC score	0.180456 (rank : 144)	θ value	0.0113563 (rank : 109)
Query Neighborhood Hits	376	Target Neighborhood Hits	119	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

DLG3_HUMAN
NC score	0.180280 (rank : 145)	θ value	2.36792 (rank : 263)
Query Neighborhood Hits	376	Target Neighborhood Hits	269	Shared Neighborhood Hits	103
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

PAR6A_MOUSE
NC score	0.179991 (rank : 146)	θ value	0.0148317 (rank : 117)
Query Neighborhood Hits	376	Target Neighborhood Hits	115	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

RASA3_MOUSE
NC score	0.179967 (rank : 147)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	376	Target Neighborhood Hits	144	Shared Neighborhood Hits	70
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

MYRIP_MOUSE
NC score	0.179902 (rank : 148)	θ value	9.29e-05 (rank : 70)
Query Neighborhood Hits	376	Target Neighborhood Hits	207	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

KPCG_MOUSE
NC score	0.179682 (rank : 149)	θ value	4.30538e-10 (rank : 31)
Query Neighborhood Hits	376	Target Neighborhood Hits	1123	Shared Neighborhood Hits	112
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

PAR6G_HUMAN
NC score	0.178908 (rank : 150)	θ value	0.0330416 (rank : 132)
Query Neighborhood Hits	376	Target Neighborhood Hits	159	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

KPCG_HUMAN
NC score	0.178712 (rank : 151)	θ value	7.34386e-10 (rank : 34)
Query Neighborhood Hits	376	Target Neighborhood Hits	1126	Shared Neighborhood Hits	112
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

SNTB1_HUMAN
NC score	0.178674 (rank : 152)	θ value	0.0431538 (rank : 137)
Query Neighborhood Hits	376	Target Neighborhood Hits	157	Shared Neighborhood Hits	87
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

LIN7A_HUMAN
NC score	0.178443 (rank : 153)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	376	Target Neighborhood Hits	193	Shared Neighborhood Hits	98
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
NC score	0.178408 (rank : 154)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	376	Target Neighborhood Hits	193	Shared Neighborhood Hits	98
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

PDZD7_HUMAN
NC score	0.176668 (rank : 155)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	376	Target Neighborhood Hits	181	Shared Neighborhood Hits	92
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

PICK1_HUMAN
NC score	0.172792 (rank : 156)	θ value	0.125558 (rank : 157)
Query Neighborhood Hits	376	Target Neighborhood Hits	132	Shared Neighborhood Hits	94
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

STXB4_HUMAN
NC score	0.171008 (rank : 157)	θ value	0.00175202 (rank : 88)
Query Neighborhood Hits	376	Target Neighborhood Hits	616	Shared Neighborhood Hits	112
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

K1849_MOUSE
NC score	0.170983 (rank : 158)	θ value	0.0563607 (rank : 140)
Query Neighborhood Hits	376	Target Neighborhood Hits	335	Shared Neighborhood Hits	99
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

STXB4_MOUSE
NC score	0.170744 (rank : 159)	θ value	0.00228821 (rank : 90)
Query Neighborhood Hits	376	Target Neighborhood Hits	629	Shared Neighborhood Hits	112
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

PA24F_MOUSE
NC score	0.170338 (rank : 160)	θ value	0.125558 (rank : 156)
Query Neighborhood Hits	376	Target Neighborhood Hits	93	Shared Neighborhood Hits	69
SwissProt Accessions	Q50L41, Q80VQ8, Q80VV9	Gene names	Pla2g4f
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

GOPC_MOUSE
NC score	0.169987 (rank : 161)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	376	Target Neighborhood Hits	323	Shared Neighborhood Hits	102
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

PICK1_MOUSE
NC score	0.169444 (rank : 162)	θ value	0.279714 (rank : 188)
Query Neighborhood Hits	376	Target Neighborhood Hits	131	Shared Neighborhood Hits	94
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

KPCA_HUMAN
NC score	0.169077 (rank : 163)	θ value	2.98157e-11 (rank : 22)
Query Neighborhood Hits	376	Target Neighborhood Hits	1070	Shared Neighborhood Hits	114
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

ZO2_MOUSE
NC score	0.167869 (rank : 164)	θ value	0.62314 (rank : 220)
Query Neighborhood Hits	376	Target Neighborhood Hits	296	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO2_HUMAN
NC score	0.167641 (rank : 165)	θ value	0.163984 (rank : 174)
Query Neighborhood Hits	376	Target Neighborhood Hits	289	Shared Neighborhood Hits	108
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO1_HUMAN
NC score	0.166854 (rank : 166)	θ value	0.163984 (rank : 173)
Query Neighborhood Hits	376	Target Neighborhood Hits	474	Shared Neighborhood Hits	107
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO1_MOUSE
NC score	0.166738 (rank : 167)	θ value	0.279714 (rank : 194)
Query Neighborhood Hits	376	Target Neighborhood Hits	453	Shared Neighborhood Hits	110
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

KPCB_MOUSE
NC score	0.166346 (rank : 168)	θ value	6.64225e-11 (rank : 25)
Query Neighborhood Hits	376	Target Neighborhood Hits	1117	Shared Neighborhood Hits	113
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

GOPC_HUMAN
NC score	0.166005 (rank : 169)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	376	Target Neighborhood Hits	377	Shared Neighborhood Hits	105
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

PAR6B_HUMAN
NC score	0.165890 (rank : 170)	θ value	0.47712 (rank : 209)
Query Neighborhood Hits	376	Target Neighborhood Hits	126	Shared Neighborhood Hits	82
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

KPCB_HUMAN
NC score	0.165415 (rank : 171)	θ value	1.02475e-11 (rank : 17)
Query Neighborhood Hits	376	Target Neighborhood Hits	1121	Shared Neighborhood Hits	114
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCA_MOUSE
NC score	0.164700 (rank : 172)	θ value	2.52405e-10 (rank : 28)
Query Neighborhood Hits	376	Target Neighborhood Hits	1067	Shared Neighborhood Hits	114
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

PAR6B_MOUSE
NC score	0.164416 (rank : 173)	θ value	0.365318 (rank : 201)
Query Neighborhood Hits	376	Target Neighborhood Hits	128	Shared Neighborhood Hits	83
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

AFAD_HUMAN
NC score	0.160674 (rank : 174)	θ value	0.163984 (rank : 162)
Query Neighborhood Hits	376	Target Neighborhood Hits	689	Shared Neighborhood Hits	134
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

K1849_HUMAN
NC score	0.160397 (rank : 175)	θ value	1.06291 (rank : 235)
Query Neighborhood Hits	376	Target Neighborhood Hits	220	Shared Neighborhood Hits	98
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

PTN13_HUMAN
NC score	0.156842 (rank : 176)	θ value	2.61198e-07 (rank : 47)
Query Neighborhood Hits	376	Target Neighborhood Hits	471	Shared Neighborhood Hits	127
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

SNTG1_MOUSE
NC score	0.154247 (rank : 177)	θ value	6.88961 (rank : 343)
Query Neighborhood Hits	376	Target Neighborhood Hits	179	Shared Neighborhood Hits	100
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

MYRIP_HUMAN
NC score	0.153161 (rank : 178)	θ value	0.0961366 (rank : 152)
Query Neighborhood Hits	376	Target Neighborhood Hits	269	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

SNTG1_HUMAN
NC score	0.151952 (rank : 179)	θ value	8.99809 (rank : 368)
Query Neighborhood Hits	376	Target Neighborhood Hits	181	Shared Neighborhood Hits	100
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

PTN13_MOUSE
NC score	0.149683 (rank : 180)	θ value	2.21117e-06 (rank : 54)
Query Neighborhood Hits	376	Target Neighborhood Hits	426	Shared Neighborhood Hits	114
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PDZ11_MOUSE
NC score	0.149028 (rank : 181)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	376	Target Neighborhood Hits	154	Shared Neighborhood Hits	78
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZ11_HUMAN
NC score	0.148289 (rank : 182)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	376	Target Neighborhood Hits	160	Shared Neighborhood Hits	82
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

DLG5_HUMAN
NC score	0.148229 (rank : 183)	θ value	0.00390308 (rank : 97)
Query Neighborhood Hits	376	Target Neighborhood Hits	1088	Shared Neighborhood Hits	145
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

PA24F_HUMAN
NC score	0.141627 (rank : 184)	θ value	3.0926 (rank : 289)
Query Neighborhood Hits	376	Target Neighborhood Hits	78	Shared Neighborhood Hits	62
SwissProt Accessions	Q68DD2, Q6ZMC8	Gene names	PLA2G4F
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

MPP5_HUMAN
NC score	0.140439 (rank : 185)	θ value	0.0431538 (rank : 135)
Query Neighborhood Hits	376	Target Neighborhood Hits	231	Shared Neighborhood Hits	99
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
NC score	0.139977 (rank : 186)	θ value	0.0431538 (rank : 136)
Query Neighborhood Hits	376	Target Neighborhood Hits	226	Shared Neighborhood Hits	97
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

PZRN4_HUMAN
NC score	0.138648 (rank : 187)	θ value	8.99809 (rank : 364)
Query Neighborhood Hits	376	Target Neighborhood Hits	438	Shared Neighborhood Hits	102
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

SMUF1_HUMAN
NC score	0.138309 (rank : 188)	θ value	0.0252991 (rank : 127)
Query Neighborhood Hits	376	Target Neighborhood Hits	135	Shared Neighborhood Hits	67
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

ITSN2_HUMAN
NC score	0.138267 (rank : 189)	θ value	0.163984 (rank : 166)
Query Neighborhood Hits	376	Target Neighborhood Hits	1173	Shared Neighborhood Hits	135
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

SMUF2_HUMAN
NC score	0.137905 (rank : 190)	θ value	0.0252991 (rank : 129)
Query Neighborhood Hits	376	Target Neighborhood Hits	142	Shared Neighborhood Hits	70
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

SMUF1_MOUSE
NC score	0.137417 (rank : 191)	θ value	0.0252991 (rank : 128)
Query Neighborhood Hits	376	Target Neighborhood Hits	142	Shared Neighborhood Hits	67
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

SRRM2_MOUSE
NC score	0.136014 (rank : 192)	θ value	0.00020696 (rank : 76)
Query Neighborhood Hits	376	Target Neighborhood Hits	1470	Shared Neighborhood Hits	110
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

NEB1_HUMAN
NC score	0.135332 (rank : 193)	θ value	8.99809 (rank : 361)
Query Neighborhood Hits	376	Target Neighborhood Hits	829	Shared Neighborhood Hits	143
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

PZRN3_MOUSE
NC score	0.135043 (rank : 194)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	376	Target Neighborhood Hits	447	Shared Neighborhood Hits	100
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_HUMAN
NC score	0.133310 (rank : 195)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	376	Target Neighborhood Hits	461	Shared Neighborhood Hits	102
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

NHRF2_MOUSE
NC score	0.131079 (rank : 196)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	376	Target Neighborhood Hits	194	Shared Neighborhood Hits	89
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

PDZD1_MOUSE
NC score	0.130845 (rank : 197)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	376	Target Neighborhood Hits	191	Shared Neighborhood Hits	84
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

NHRF2_HUMAN
NC score	0.130470 (rank : 198)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	376	Target Neighborhood Hits	197	Shared Neighborhood Hits	88
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

TX1B3_HUMAN
NC score	0.130239 (rank : 199)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	376	Target Neighborhood Hits	161	Shared Neighborhood Hits	84
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

ITSN2_MOUSE
NC score	0.128799 (rank : 200)	θ value	0.813845 (rank : 225)
Query Neighborhood Hits	376	Target Neighborhood Hits	1371	Shared Neighborhood Hits	149
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

LAP4_HUMAN
NC score	0.128566 (rank : 201)	θ value	0.0431538 (rank : 134)
Query Neighborhood Hits	376	Target Neighborhood Hits	608	Shared Neighborhood Hits	116
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

PDZD1_HUMAN
NC score	0.128270 (rank : 202)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	376	Target Neighborhood Hits	190	Shared Neighborhood Hits	85
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

TX1B3_MOUSE
NC score	0.127649 (rank : 203)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	376	Target Neighborhood Hits	158	Shared Neighborhood Hits	83
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

LAP4_MOUSE
NC score	0.127291 (rank : 204)	θ value	0.0961366 (rank : 151)
Query Neighborhood Hits	376	Target Neighborhood Hits	590	Shared Neighborhood Hits	112
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

MPP4_HUMAN
NC score	0.126718 (rank : 205)	θ value	0.47712 (rank : 208)
Query Neighborhood Hits	376	Target Neighborhood Hits	205	Shared Neighborhood Hits	92
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

CPNE3_HUMAN
NC score	0.126512 (rank : 206)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	376	Target Neighborhood Hits	90	Shared Neighborhood Hits	65
SwissProt Accessions	O75131, Q8IYA1	Gene names	CPNE3, CPN3, KIAA0636
Domain Architecture
Description	Copine-3 (Copine III).

CPNE3_MOUSE
NC score	0.125882 (rank : 207)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	376	Target Neighborhood Hits	90	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BT60, Q5CZX9, Q5DU22	Gene names	Cpne3, Kiaa0636
Domain Architecture
Description	Copine-3 (Copine III).

NHERF_HUMAN
NC score	0.125871 (rank : 208)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	376	Target Neighborhood Hits	190	Shared Neighborhood Hits	83
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NHERF_MOUSE
NC score	0.125510 (rank : 209)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	376	Target Neighborhood Hits	195	Shared Neighborhood Hits	87
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NIPBL_HUMAN
NC score	0.123666 (rank : 210)	θ value	7.1131e-05 (rank : 69)
Query Neighborhood Hits	376	Target Neighborhood Hits	1311	Shared Neighborhood Hits	129
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

GIPC1_MOUSE
NC score	0.122450 (rank : 211)	θ value	0.0961366 (rank : 150)
Query Neighborhood Hits	376	Target Neighborhood Hits	92	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

SRRM2_HUMAN
NC score	0.121331 (rank : 212)	θ value	0.000461057 (rank : 82)
Query Neighborhood Hits	376	Target Neighborhood Hits	1296	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

APBA1_HUMAN
NC score	0.119461 (rank : 213)	θ value	0.813845 (rank : 221)
Query Neighborhood Hits	376	Target Neighborhood Hits	325	Shared Neighborhood Hits	99
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

GIPC1_HUMAN
NC score	0.118938 (rank : 214)	θ value	0.125558 (rank : 154)
Query Neighborhood Hits	376	Target Neighborhood Hits	91	Shared Neighborhood Hits	62
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

DVL3_MOUSE
NC score	0.117718 (rank : 215)	θ value	2.36792 (rank : 267)
Query Neighborhood Hits	376	Target Neighborhood Hits	198	Shared Neighborhood Hits	89
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

CPNE5_MOUSE
NC score	0.117337 (rank : 216)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	376	Target Neighborhood Hits	86	Shared Neighborhood Hits	62
SwissProt Accessions	Q8JZW4	Gene names	Cpne5
Domain Architecture
Description	Copine-5 (Copine V).

CPNE5_HUMAN
NC score	0.117090 (rank : 217)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	376	Target Neighborhood Hits	88	Shared Neighborhood Hits	62
SwissProt Accessions	Q9HCH3	Gene names	CPNE5, KIAA1599
Domain Architecture
Description	Copine-5 (Copine V).

NPBL_MOUSE
NC score	0.116673 (rank : 218)	θ value	0.125558 (rank : 155)
Query Neighborhood Hits	376	Target Neighborhood Hits	1041	Shared Neighborhood Hits	111
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

DVL3_HUMAN
NC score	0.116518 (rank : 219)	θ value	2.36792 (rank : 266)
Query Neighborhood Hits	376	Target Neighborhood Hits	194	Shared Neighborhood Hits	85
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

SDCB1_MOUSE
NC score	0.116018 (rank : 220)	θ value	0.813845 (rank : 229)
Query Neighborhood Hits	376	Target Neighborhood Hits	144	Shared Neighborhood Hits	77
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

ITSN1_MOUSE
NC score	0.115695 (rank : 221)	θ value	0.279714 (rank : 187)
Query Neighborhood Hits	376	Target Neighborhood Hits	1669	Shared Neighborhood Hits	177
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ITSN1_HUMAN
NC score	0.115295 (rank : 222)	θ value	0.0736092 (rank : 146)
Query Neighborhood Hits	376	Target Neighborhood Hits	1757	Shared Neighborhood Hits	170
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

NEB2_MOUSE
NC score	0.115019 (rank : 223)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	376	Target Neighborhood Hits	889	Shared Neighborhood Hits	130
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

PDZD3_HUMAN
NC score	0.114485 (rank : 224)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	376	Target Neighborhood Hits	180	Shared Neighborhood Hits	83
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

PDZK4_MOUSE
NC score	0.114385 (rank : 225)	θ value	2.36792 (rank : 272)
Query Neighborhood Hits	376	Target Neighborhood Hits	165	Shared Neighborhood Hits	92
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

RSRC1_HUMAN
NC score	0.113745 (rank : 226)	θ value	0.0148317 (rank : 118)
Query Neighborhood Hits	376	Target Neighborhood Hits	108	Shared Neighborhood Hits	20
SwissProt Accessions	Q96IZ7, Q96QK2, Q9NZE5	Gene names	RSRC1
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich coiled coil protein 1.

NEB2_HUMAN
NC score	0.113644 (rank : 227)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	376	Target Neighborhood Hits	883	Shared Neighborhood Hits	127
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

CPNE8_HUMAN
NC score	0.113132 (rank : 228)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	376	Target Neighborhood Hits	86	Shared Neighborhood Hits	62
SwissProt Accessions	Q86YQ8, Q2TB41	Gene names	CPNE8
Domain Architecture
Description	Copine-8 (Copine VIII).

SDCB1_HUMAN
NC score	0.113063 (rank : 229)	θ value	1.38821 (rank : 247)
Query Neighborhood Hits	376	Target Neighborhood Hits	150	Shared Neighborhood Hits	84
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

CPNE2_MOUSE
NC score	0.112729 (rank : 230)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	376	Target Neighborhood Hits	82	Shared Neighborhood Hits	58
SwissProt Accessions	P59108, Q8K1D7	Gene names	Cpne2
Domain Architecture
Description	Copine-2 (Copine II).

CPNE2_HUMAN
NC score	0.112363 (rank : 231)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	376	Target Neighborhood Hits	75	Shared Neighborhood Hits	55
SwissProt Accessions	Q96FN4, Q68D19, Q86XP9	Gene names	CPNE2
Domain Architecture
Description	Copine-2 (Copine II).

APBA2_MOUSE
NC score	0.112183 (rank : 232)	θ value	8.99809 (rank : 349)
Query Neighborhood Hits	376	Target Neighborhood Hits	219	Shared Neighborhood Hits	92
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

DVL2_MOUSE
NC score	0.112138 (rank : 233)	θ value	2.36792 (rank : 265)
Query Neighborhood Hits	376	Target Neighborhood Hits	233	Shared Neighborhood Hits	86
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

PDZD3_MOUSE
NC score	0.111122 (rank : 234)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	376	Target Neighborhood Hits	171	Shared Neighborhood Hits	82
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

SFR11_HUMAN
NC score	0.110836 (rank : 235)	θ value	0.00298849 (rank : 95)
Query Neighborhood Hits	376	Target Neighborhood Hits	246	Shared Neighborhood Hits	40
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

CPNE8_MOUSE
NC score	0.110118 (rank : 236)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	376	Target Neighborhood Hits	85	Shared Neighborhood Hits	62
SwissProt Accessions	Q9DC53, Q9CUZ8	Gene names	Cpne8
Domain Architecture
Description	Copine-8 (Copine VIII).

DVL2_HUMAN
NC score	0.109485 (rank : 237)	θ value	6.88961 (rank : 329)
Query Neighborhood Hits	376	Target Neighborhood Hits	223	Shared Neighborhood Hits	89
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

CPNE1_MOUSE
NC score	0.109065 (rank : 238)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	376	Target Neighborhood Hits	83	Shared Neighborhood Hits	61
SwissProt Accessions	Q8C166, Q925K4, Q925K5	Gene names	Cpne1
Domain Architecture
Description	Copine-1 (Copine I).

DVL1_HUMAN
NC score	0.108408 (rank : 239)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	376	Target Neighborhood Hits	158	Shared Neighborhood Hits	85
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL1_MOUSE
NC score	0.106795 (rank : 240)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	376	Target Neighborhood Hits	146	Shared Neighborhood Hits	83
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

GPTC8_HUMAN
NC score	0.105207 (rank : 241)	θ value	0.0330416 (rank : 131)
Query Neighborhood Hits	376	Target Neighborhood Hits	366	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

MPP3_HUMAN
NC score	0.104702 (rank : 242)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	376	Target Neighborhood Hits	171	Shared Neighborhood Hits	90
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

SRRM1_MOUSE
NC score	0.104551 (rank : 243)	θ value	0.21417 (rank : 184)
Query Neighborhood Hits	376	Target Neighborhood Hits	966	Shared Neighborhood Hits	85
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

MPP3_MOUSE
NC score	0.104531 (rank : 244)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	376	Target Neighborhood Hits	165	Shared Neighborhood Hits	90
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

WWC1_MOUSE
NC score	0.104449 (rank : 245)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	376	Target Neighborhood Hits	290	Shared Neighborhood Hits	61
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

APBA2_HUMAN
NC score	0.101920 (rank : 246)	θ value	8.99809 (rank : 348)
Query Neighborhood Hits	376	Target Neighborhood Hits	220	Shared Neighborhood Hits	92
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

DVL1L_HUMAN
NC score	0.099951 (rank : 247)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	376	Target Neighborhood Hits	146	Shared Neighborhood Hits	80
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

SFR12_MOUSE
NC score	0.099776 (rank : 248)	θ value	0.00509761 (rank : 101)
Query Neighborhood Hits	376	Target Neighborhood Hits	486	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

CPNE7_HUMAN
NC score	0.098284 (rank : 249)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	376	Target Neighborhood Hits	92	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UBL6	Gene names	CPNE7
Domain Architecture
Description	Copine-7 (Copine VII).

APXL_HUMAN
NC score	0.098125 (rank : 250)	θ value	3.0926 (rank : 279)
Query Neighborhood Hits	376	Target Neighborhood Hits	553	Shared Neighborhood Hits	82
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

MPP4_MOUSE
NC score	0.097851 (rank : 251)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	376	Target Neighborhood Hits	188	Shared Neighborhood Hits	83
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

NOS1_HUMAN
NC score	0.097212 (rank : 252)	θ value	1.81305 (rank : 258)
Query Neighborhood Hits	376	Target Neighborhood Hits	218	Shared Neighborhood Hits	92
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

SRRM1_HUMAN
NC score	0.095169 (rank : 253)	θ value	0.0330416 (rank : 133)
Query Neighborhood Hits	376	Target Neighborhood Hits	690	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

RFIP1_MOUSE
NC score	0.094208 (rank : 254)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	376	Target Neighborhood Hits	152	Shared Neighborhood Hits	43
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

PDZK4_HUMAN
NC score	0.094007 (rank : 255)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	376	Target Neighborhood Hits	165	Shared Neighborhood Hits	83
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

GIPC2_HUMAN
NC score	0.093739 (rank : 256)	θ value	1.81305 (rank : 254)
Query Neighborhood Hits	376	Target Neighborhood Hits	93	Shared Neighborhood Hits	67
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

CCD55_MOUSE
NC score	0.093061 (rank : 257)	θ value	2.36792 (rank : 261)
Query Neighborhood Hits	376	Target Neighborhood Hits	519	Shared Neighborhood Hits	96
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

MELPH_MOUSE
NC score	0.093040 (rank : 258)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	376	Target Neighborhood Hits	112	Shared Neighborhood Hits	18
SwissProt Accessions	Q91V27, Q99N53	Gene names	Mlph, Ln, Slac2a
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Leaden protein) (Synaptotagmin-like protein 2a) (Slac2-a) (Slp homolog lacking C2 domains a).

APBA3_HUMAN
NC score	0.092911 (rank : 259)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	376	Target Neighborhood Hits	201	Shared Neighborhood Hits	87
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

MELPH_HUMAN
NC score	0.091582 (rank : 260)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	376	Target Neighborhood Hits	145	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BV36, Q9HA71	Gene names	MLPH, SLAC2A
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Synaptotagmin-like protein 2a) (Slp homolog lacking C2 domains a).

SFRIP_HUMAN
NC score	0.091219 (rank : 261)	θ value	0.62314 (rank : 217)
Query Neighborhood Hits	376	Target Neighborhood Hits	530	Shared Neighborhood Hits	70
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

CPNE1_HUMAN
NC score	0.090866 (rank : 262)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	376	Target Neighborhood Hits	70	Shared Neighborhood Hits	54
SwissProt Accessions	Q99829, Q6IBL3, Q9H243, Q9NTZ7	Gene names	CPNE1, CPN1
Domain Architecture
Description	Copine-1 (Copine I).

RGS12_HUMAN
NC score	0.090565 (rank : 263)	θ value	0.62314 (rank : 216)
Query Neighborhood Hits	376	Target Neighborhood Hits	333	Shared Neighborhood Hits	85
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

RFIP1_HUMAN
NC score	0.089805 (rank : 264)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	376	Target Neighborhood Hits	236	Shared Neighborhood Hits	51
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

BSN_MOUSE
NC score	0.089681 (rank : 265)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	376	Target Neighborhood Hits	2057	Shared Neighborhood Hits	95
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CCD55_HUMAN
NC score	0.089212 (rank : 266)	θ value	3.0926 (rank : 280)
Query Neighborhood Hits	376	Target Neighborhood Hits	513	Shared Neighborhood Hits	91
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

RSRC1_MOUSE
NC score	0.088758 (rank : 267)	θ value	0.125558 (rank : 158)
Query Neighborhood Hits	376	Target Neighborhood Hits	93	Shared Neighborhood Hits	21
SwissProt Accessions	Q9DBU6, Q3TF06	Gene names	Rsrc1
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich coiled coil protein 1.

SFR12_HUMAN
NC score	0.088233 (rank : 268)	θ value	0.00228821 (rank : 89)
Query Neighborhood Hits	376	Target Neighborhood Hits	553	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

EM55_MOUSE
NC score	0.087851 (rank : 269)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	376	Target Neighborhood Hits	221	Shared Neighborhood Hits	89
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

GP143_HUMAN
NC score	0.087273 (rank : 270)	θ value	0.0193708 (rank : 120)
Query Neighborhood Hits	376	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	P51810	Gene names	GPR143, OA1
Domain Architecture
Description	G-protein coupled receptor 143 (Ocular albinism type 1 protein).

EM55_HUMAN
NC score	0.087223 (rank : 271)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	376	Target Neighborhood Hits	228	Shared Neighborhood Hits	89
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

FA47A_HUMAN
NC score	0.086299 (rank : 272)	θ value	0.163984 (rank : 163)
Query Neighborhood Hits	376	Target Neighborhood Hits	451	Shared Neighborhood Hits	34
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

APBA3_MOUSE
NC score	0.085579 (rank : 273)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	376	Target Neighborhood Hits	174	Shared Neighborhood Hits	82
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

BSN_HUMAN
NC score	0.085300 (rank : 274)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	376	Target Neighborhood Hits	1537	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

IWS1_HUMAN
NC score	0.084827 (rank : 275)	θ value	0.47712 (rank : 206)
Query Neighborhood Hits	376	Target Neighborhood Hits	1241	Shared Neighborhood Hits	101
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

TARA_HUMAN
NC score	0.084755 (rank : 276)	θ value	0.62314 (rank : 219)
Query Neighborhood Hits	376	Target Neighborhood Hits	1626	Shared Neighborhood Hits	123
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

WWC1_HUMAN
NC score	0.083460 (rank : 277)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	376	Target Neighborhood Hits	290	Shared Neighborhood Hits	58
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

SYNP2_MOUSE
NC score	0.082872 (rank : 278)	θ value	2.36792 (rank : 275)
Query Neighborhood Hits	376	Target Neighborhood Hits	252	Shared Neighborhood Hits	74
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

PLCD1_HUMAN
NC score	0.082578 (rank : 279)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	376	Target Neighborhood Hits	93	Shared Neighborhood Hits	50
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

CPNE6_HUMAN
NC score	0.082577 (rank : 280)	θ value	6.88961 (rank : 327)
Query Neighborhood Hits	376	Target Neighborhood Hits	85	Shared Neighborhood Hits	56
SwissProt Accessions	O95741, Q53HA6, Q8WVG1	Gene names	CPNE6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

SDCB2_MOUSE
NC score	0.082510 (rank : 281)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	376	Target Neighborhood Hits	118	Shared Neighborhood Hits	68
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

CPNE6_MOUSE
NC score	0.081814 (rank : 282)	θ value	8.99809 (rank : 353)
Query Neighborhood Hits	376	Target Neighborhood Hits	87	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z140	Gene names	Cpne6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

SNUT3_HUMAN
NC score	0.081674 (rank : 283)	θ value	2.36792 (rank : 274)
Query Neighborhood Hits	376	Target Neighborhood Hits	52	Shared Neighborhood Hits	17
SwissProt Accessions	Q8WVK2, Q15410	Gene names
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 3 (U4/U6.U5 tri-snRNP-associated 27 kDa protein) (27K) (Nucleic acid-binding protein RY-1).

ZC313_HUMAN
NC score	0.081136 (rank : 284)	θ value	0.00869519 (rank : 106)
Query Neighborhood Hits	376	Target Neighborhood Hits	772	Shared Neighborhood Hits	91
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

WWP1_HUMAN
NC score	0.080637 (rank : 285)	θ value	0.279714 (rank : 193)
Query Neighborhood Hits	376	Target Neighborhood Hits	262	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

RPGF6_HUMAN
NC score	0.079864 (rank : 286)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	376	Target Neighborhood Hits	266	Shared Neighborhood Hits	89
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

GIPC2_MOUSE
NC score	0.079417 (rank : 287)	θ value	1.06291 (rank : 232)
Query Neighborhood Hits	376	Target Neighborhood Hits	71	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Z2H7, Q9CVG2	Gene names	Gipc2, Semcap2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain- associated protein 2) (SEMCAP-2).

IWS1_MOUSE
NC score	0.079026 (rank : 288)	θ value	1.38821 (rank : 244)
Query Neighborhood Hits	376	Target Neighborhood Hits	1258	Shared Neighborhood Hits	103
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NOS1_MOUSE
NC score	0.078350 (rank : 289)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	376	Target Neighborhood Hits	155	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

SDCB2_HUMAN
NC score	0.077486 (rank : 290)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	376	Target Neighborhood Hits	121	Shared Neighborhood Hits	61
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

ITCH_HUMAN
NC score	0.076534 (rank : 291)	θ value	0.21417 (rank : 177)
Query Neighborhood Hits	376	Target Neighborhood Hits	162	Shared Neighborhood Hits	37
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

PDLI2_HUMAN
NC score	0.076263 (rank : 292)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	376	Target Neighborhood Hits	245	Shared Neighborhood Hits	69
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

MPP6_MOUSE
NC score	0.075883 (rank : 293)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	376	Target Neighborhood Hits	187	Shared Neighborhood Hits	76
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

MPP6_HUMAN
NC score	0.075595 (rank : 294)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	376	Target Neighborhood Hits	180	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

SNUT3_MOUSE
NC score	0.074187 (rank : 295)	θ value	6.88961 (rank : 344)
Query Neighborhood Hits	376	Target Neighborhood Hits	50	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K194, Q8BRA8, Q9CSV0	Gene names
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 3.

SYP2L_HUMAN
NC score	0.073552 (rank : 296)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	376	Target Neighborhood Hits	400	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

CPNE4_HUMAN
NC score	0.073414 (rank : 297)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	376	Target Neighborhood Hits	70	Shared Neighborhood Hits	50
SwissProt Accessions	Q96A23, Q8TEX1	Gene names	CPNE4
Domain Architecture
Description	Copine-4 (Copine IV) (Copine-8).

MPP2_MOUSE
NC score	0.073037 (rank : 298)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	376	Target Neighborhood Hits	189	Shared Neighborhood Hits	74
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

MPP2_HUMAN
NC score	0.072887 (rank : 299)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	376	Target Neighborhood Hits	173	Shared Neighborhood Hits	71
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

ARHGB_HUMAN
NC score	0.072500 (rank : 300)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	376	Target Neighborhood Hits	375	Shared Neighborhood Hits	95
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

RBBP6_HUMAN
NC score	0.072302 (rank : 301)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	376	Target Neighborhood Hits	1135	Shared Neighborhood Hits	110
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

GIPC3_MOUSE
NC score	0.072136 (rank : 302)	θ value	6.88961 (rank : 334)
Query Neighborhood Hits	376	Target Neighborhood Hits	53	Shared Neighborhood Hits	39
SwissProt Accessions	Q8R5M0	Gene names	Gipc3, Rgs19ip3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3).

CPNE4_MOUSE
NC score	0.071940 (rank : 303)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	376	Target Neighborhood Hits	67	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BLR2	Gene names	Cpne4
Domain Architecture	No domain graphic available
Description	Copine-4 (Copine IV).

GIPC3_HUMAN
NC score	0.071271 (rank : 304)	θ value	6.88961 (rank : 333)
Query Neighborhood Hits	376	Target Neighborhood Hits	52	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TF64, O75227	Gene names	GIPC3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3.

ITCH_MOUSE
NC score	0.071022 (rank : 305)	θ value	1.81305 (rank : 255)
Query Neighborhood Hits	376	Target Neighborhood Hits	127	Shared Neighborhood Hits	33
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

RHPN1_MOUSE
NC score	0.070989 (rank : 306)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	376	Target Neighborhood Hits	154	Shared Neighborhood Hits	68
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

GRASP_HUMAN
NC score	0.069404 (rank : 307)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	376	Target Neighborhood Hits	147	Shared Neighborhood Hits	61
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

PRP40_MOUSE
NC score	0.068509 (rank : 308)	θ value	0.21417 (rank : 182)
Query Neighborhood Hits	376	Target Neighborhood Hits	447	Shared Neighborhood Hits	57
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

WWP1_MOUSE
NC score	0.067671 (rank : 309)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	376	Target Neighborhood Hits	138	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

PDLI2_MOUSE
NC score	0.066810 (rank : 310)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	376	Target Neighborhood Hits	220	Shared Neighborhood Hits	64
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

BCLF1_HUMAN
NC score	0.066521 (rank : 311)	θ value	0.0736092 (rank : 143)
Query Neighborhood Hits	376	Target Neighborhood Hits	298	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NYF8, Q14673, Q86WU6, Q86WY0	Gene names	BCLAF1, BTF, KIAA0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

ARHGC_MOUSE
NC score	0.065809 (rank : 312)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	376	Target Neighborhood Hits	344	Shared Neighborhood Hits	93
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

RPGF2_HUMAN
NC score	0.065675 (rank : 313)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	376	Target Neighborhood Hits	242	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

ARHGC_HUMAN
NC score	0.065636 (rank : 314)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	376	Target Neighborhood Hits	351	Shared Neighborhood Hits	91
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

GRASP_MOUSE
NC score	0.065531 (rank : 315)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	376	Target Neighborhood Hits	131	Shared Neighborhood Hits	57
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

TGON2_HUMAN
NC score	0.064634 (rank : 316)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	376	Target Neighborhood Hits	1037	Shared Neighborhood Hits	81
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

SLC2B_HUMAN
NC score	0.064492 (rank : 317)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	376	Target Neighborhood Hits	214	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

RBBP6_MOUSE
NC score	0.063671 (rank : 318)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	376	Target Neighborhood Hits	1014	Shared Neighborhood Hits	100
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

LC7L2_MOUSE
NC score	0.063552 (rank : 319)	θ value	0.21417 (rank : 179)
Query Neighborhood Hits	376	Target Neighborhood Hits	244	Shared Neighborhood Hits	33
SwissProt Accessions	Q7TNC4, Q99LM5, Q99PC3	Gene names	Luc7l2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2 (CGI-74 homolog).

RHPN1_HUMAN
NC score	0.063365 (rank : 320)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	376	Target Neighborhood Hits	158	Shared Neighborhood Hits	65
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

LC7L2_HUMAN
NC score	0.063176 (rank : 321)	θ value	0.163984 (rank : 167)
Query Neighborhood Hits	376	Target Neighborhood Hits	235	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y383, Q8IUP9, Q9NVL3, Q9NVN7, Q9UQN1	Gene names	LUC7L2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2.

IBRD1_HUMAN
NC score	0.063113 (rank : 322)	θ value	0.163984 (rank : 165)
Query Neighborhood Hits	376	Target Neighborhood Hits	62	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TC41, Q9BX48	Gene names	IBRDC1
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 1.

PDZD8_HUMAN
NC score	0.062924 (rank : 323)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	376	Target Neighborhood Hits	185	Shared Neighborhood Hits	38
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

WWP2_HUMAN
NC score	0.062710 (rank : 324)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	376	Target Neighborhood Hits	177	Shared Neighborhood Hits	32
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

TARA_MOUSE
NC score	0.062466 (rank : 325)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	376	Target Neighborhood Hits	1133	Shared Neighborhood Hits	91
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CROP_HUMAN
NC score	0.062280 (rank : 326)	θ value	0.0961366 (rank : 149)
Query Neighborhood Hits	376	Target Neighborhood Hits	402	Shared Neighborhood Hits	49
SwissProt Accessions	O95232, Q6PHR9, Q9NUY0, Q9P2S7	Gene names	CROP, CREAP1, O48
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18).

BCLF1_MOUSE
NC score	0.062068 (rank : 327)	θ value	0.0736092 (rank : 144)
Query Neighborhood Hits	376	Target Neighborhood Hits	303	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K019, Q8BNZ0, Q8C2E9, Q9CSW5	Gene names	Bclaf1, Btf, Kiaa0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

SON_MOUSE
NC score	0.061880 (rank : 328)	θ value	0.279714 (rank : 192)
Query Neighborhood Hits	376	Target Neighborhood Hits	957	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

PSCBP_MOUSE
NC score	0.061748 (rank : 329)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	376	Target Neighborhood Hits	118	Shared Neighborhood Hits	61
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

WWP2_MOUSE
NC score	0.061736 (rank : 330)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	376	Target Neighborhood Hits	118	Shared Neighborhood Hits	25
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

TXND2_MOUSE
NC score	0.061449 (rank : 331)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	376	Target Neighborhood Hits	828	Shared Neighborhood Hits	86
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

PK3CG_HUMAN
NC score	0.061391 (rank : 332)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	376	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	P48736, Q8IV23, Q9BZC8	Gene names	PIK3CG
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PK3CG_MOUSE
NC score	0.061267 (rank : 333)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	376	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JHG7	Gene names	Pik3cg, Pi3kg1
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

TCRG1_MOUSE
NC score	0.060880 (rank : 334)	θ value	3.0926 (rank : 294)
Query Neighborhood Hits	376	Target Neighborhood Hits	947	Shared Neighborhood Hits	95
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TCRG1_HUMAN
NC score	0.060880 (rank : 335)	θ value	3.0926 (rank : 293)
Query Neighborhood Hits	376	Target Neighborhood Hits	929	Shared Neighborhood Hits	93
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

PK3CA_MOUSE
NC score	0.059668 (rank : 336)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	376	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	P42337	Gene names	Pik3ca
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

PK3CA_HUMAN
NC score	0.059616 (rank : 337)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	376	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	P42336, Q99762	Gene names	PIK3CA
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

YTDC1_HUMAN
NC score	0.058577 (rank : 338)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	376	Target Neighborhood Hits	458	Shared Neighborhood Hits	68
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

TRIPC_HUMAN
NC score	0.057293 (rank : 339)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	376	Target Neighborhood Hits	319	Shared Neighborhood Hits	53
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

CROP_MOUSE
NC score	0.057058 (rank : 340)	θ value	1.81305 (rank : 252)
Query Neighborhood Hits	376	Target Neighborhood Hits	403	Shared Neighborhood Hits	47
SwissProt Accessions	Q5SUF2, Q3U9D5, Q8BUJ5, Q921Z3, Q9CRS7, Q9CTY4	Gene names	Crop
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein.

PK3CD_MOUSE
NC score	0.056955 (rank : 341)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	376	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	O35904	Gene names	Pik3cd
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

PK3CD_HUMAN
NC score	0.056847 (rank : 342)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	376	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	O00329, O15445	Gene names	PIK3CD
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

MDC1_HUMAN
NC score	0.056826 (rank : 343)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	376	Target Neighborhood Hits	1446	Shared Neighborhood Hits	98
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

SFRS4_HUMAN
NC score	0.056541 (rank : 344)	θ value	0.125558 (rank : 159)
Query Neighborhood Hits	376	Target Neighborhood Hits	384	Shared Neighborhood Hits	37
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

GRP3_HUMAN
NC score	0.056529 (rank : 345)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	376	Target Neighborhood Hits	131	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

PK3CB_MOUSE
NC score	0.056219 (rank : 346)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	376	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BTI9	Gene names	Pik3cb
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

RN168_HUMAN
NC score	0.056177 (rank : 347)	θ value	0.0252991 (rank : 126)
Query Neighborhood Hits	376	Target Neighborhood Hits	370	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

ELOA1_HUMAN
NC score	0.056175 (rank : 348)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	376	Target Neighborhood Hits	388	Shared Neighborhood Hits	71
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

PK3CB_HUMAN
NC score	0.056174 (rank : 349)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	376	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	P42338	Gene names	PIK3CB
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

YAP1_MOUSE
NC score	0.055814 (rank : 350)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	376	Target Neighborhood Hits	96	Shared Neighborhood Hits	25
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

PLCD1_MOUSE
NC score	0.055584 (rank : 351)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	376	Target Neighborhood Hits	106	Shared Neighborhood Hits	50
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

TXND2_HUMAN
NC score	0.055487 (rank : 352)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	376	Target Neighborhood Hits	793	Shared Neighborhood Hits	58
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

RPTN_MOUSE
NC score	0.054438 (rank : 353)	θ value	0.21417 (rank : 183)
Query Neighborhood Hits	376	Target Neighborhood Hits	650	Shared Neighborhood Hits	81
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

PA24C_HUMAN
NC score	0.054336 (rank : 354)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	376	Target Neighborhood Hits	13	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UP65, O75457, Q9UG68	Gene names	PLA2G4C
Domain Architecture
Description	Cytosolic phospholipase A2 gamma precursor (EC 3.1.1.4) (cPLA2-gamma) (Phospholipase A2 group IVC).

SYNP2_HUMAN
NC score	0.053941 (rank : 355)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	376	Target Neighborhood Hits	323	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

PSCBP_HUMAN
NC score	0.053520 (rank : 356)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	376	Target Neighborhood Hits	123	Shared Neighborhood Hits	59
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

RPTN_HUMAN
NC score	0.053363 (rank : 357)	θ value	0.365318 (rank : 202)
Query Neighborhood Hits	376	Target Neighborhood Hits	406	Shared Neighborhood Hits	63
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

LEO1_HUMAN
NC score	0.053336 (rank : 358)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	376	Target Neighborhood Hits	958	Shared Neighborhood Hits	86
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

PK3C3_HUMAN
NC score	0.053064 (rank : 359)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	376	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NEB9, Q15134	Gene names	PIK3C3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3) (Phosphatidylinositol 3-kinase p100 subunit).

MINT_HUMAN
NC score	0.053001 (rank : 360)	θ value	0.813845 (rank : 228)
Query Neighborhood Hits	376	Target Neighborhood Hits	1291	Shared Neighborhood Hits	91
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PK3C3_MOUSE
NC score	0.052846 (rank : 361)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	376	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PF93, Q8R3S8	Gene names	Pik3c3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3).

ACINU_HUMAN
NC score	0.052655 (rank : 362)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	376	Target Neighborhood Hits	828	Shared Neighborhood Hits	91
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

NKTR_HUMAN
NC score	0.052609 (rank : 363)	θ value	1.81305 (rank : 257)
Query Neighborhood Hits	376	Target Neighborhood Hits	658	Shared Neighborhood Hits	95
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

PI4KA_HUMAN
NC score	0.052537 (rank : 364)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	376	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	P42356, Q7Z625, Q9UPG2	Gene names	PIK4CA, PIK4
Domain Architecture
Description	Phosphatidylinositol 4-kinase alpha (EC 2.7.1.67) (PI4-kinase alpha) (PtdIns-4-kinase alpha) (PI4K-alpha).

HUWE1_HUMAN
NC score	0.052129 (rank : 365)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	376	Target Neighborhood Hits	443	Shared Neighborhood Hits	34
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HUWE1_MOUSE
NC score	0.052050 (rank : 366)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	376	Target Neighborhood Hits	406	Shared Neighborhood Hits	37
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

FILA_HUMAN
NC score	0.050973 (rank : 367)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	376	Target Neighborhood Hits	685	Shared Neighborhood Hits	82
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

C8AP2_HUMAN
NC score	0.050691 (rank : 368)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	376	Target Neighborhood Hits	548	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

TR150_MOUSE
NC score	0.050465 (rank : 369)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	376	Target Neighborhood Hits	468	Shared Neighborhood Hits	69
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

K0408_HUMAN
NC score	0.050368 (rank : 370)	θ value	0.21417 (rank : 178)
Query Neighborhood Hits	376	Target Neighborhood Hits	101	Shared Neighborhood Hits	14
SwissProt Accessions	Q6ZU52, O43158, Q5TF20, Q7L2M2	Gene names	KIAA0408
Domain Architecture	No domain graphic available
Description	Protein KIAA0408.

NOLC1_HUMAN
NC score	0.050318 (rank : 371)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	376	Target Neighborhood Hits	452	Shared Neighborhood Hits	31
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

ATRX_MOUSE
NC score	0.049966 (rank : 372)	θ value	0.0961366 (rank : 148)
Query Neighborhood Hits	376	Target Neighborhood Hits	682	Shared Neighborhood Hits	62
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

CXCC1_MOUSE
NC score	0.049744 (rank : 373)	θ value	0.365318 (rank : 195)
Query Neighborhood Hits	376	Target Neighborhood Hits	124	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

SON_HUMAN
NC score	0.049313 (rank : 374)	θ value	0.163984 (rank : 172)
Query Neighborhood Hits	376	Target Neighborhood Hits	1568	Shared Neighborhood Hits	73
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

MYST3_HUMAN
NC score	0.049210 (rank : 375)	θ value	0.21417 (rank : 180)
Query Neighborhood Hits	376	Target Neighborhood Hits	772	Shared Neighborhood Hits	58
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

SFRS4_MOUSE
NC score	0.049170 (rank : 376)	θ value	0.62314 (rank : 218)
Query Neighborhood Hits	376	Target Neighborhood Hits	406	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

MYST3_MOUSE
NC score	0.048642 (rank : 377)	θ value	0.21417 (rank : 181)
Query Neighborhood Hits	376	Target Neighborhood Hits	688	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

SRCH_HUMAN
NC score	0.047868 (rank : 378)	θ value	3.0926 (rank : 292)
Query Neighborhood Hits	376	Target Neighborhood Hits	225	Shared Neighborhood Hits	28
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

PININ_HUMAN
NC score	0.047141 (rank : 379)	θ value	3.0926 (rank : 290)
Query Neighborhood Hits	376	Target Neighborhood Hits	753	Shared Neighborhood Hits	82
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

SETD2_HUMAN
NC score	0.046025 (rank : 380)	θ value	0.813845 (rank : 230)
Query Neighborhood Hits	376	Target Neighborhood Hits	412	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

CK5P2_HUMAN
NC score	0.044513 (rank : 381)	θ value	0.0330416 (rank : 130)
Query Neighborhood Hits	376	Target Neighborhood Hits	1433	Shared Neighborhood Hits	96
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

TRHY_HUMAN
NC score	0.044103 (rank : 382)	θ value	0.000461057 (rank : 84)
Query Neighborhood Hits	376	Target Neighborhood Hits	1385	Shared Neighborhood Hits	85
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

HRX_HUMAN
NC score	0.043880 (rank : 383)	θ value	0.47712 (rank : 205)
Query Neighborhood Hits	376	Target Neighborhood Hits	825	Shared Neighborhood Hits	68
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

HGS_MOUSE
NC score	0.043528 (rank : 384)	θ value	0.0252991 (rank : 124)
Query Neighborhood Hits	376	Target Neighborhood Hits	589	Shared Neighborhood Hits	42
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

PPIG_HUMAN
NC score	0.043185 (rank : 385)	θ value	8.99809 (rank : 363)
Query Neighborhood Hits	376	Target Neighborhood Hits	670	Shared Neighborhood Hits	87
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

LAD1_HUMAN
NC score	0.041527 (rank : 386)	θ value	6.88961 (rank : 338)
Query Neighborhood Hits	376	Target Neighborhood Hits	441	Shared Neighborhood Hits	46
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

HIRP3_HUMAN
NC score	0.041417 (rank : 387)	θ value	6.88961 (rank : 335)
Query Neighborhood Hits	376	Target Neighborhood Hits	323	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

RNPS1_HUMAN
NC score	0.041292 (rank : 388)	θ value	0.279714 (rank : 190)
Query Neighborhood Hits	376	Target Neighborhood Hits	285	Shared Neighborhood Hits	22
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
NC score	0.041292 (rank : 389)	θ value	0.279714 (rank : 191)
Query Neighborhood Hits	376	Target Neighborhood Hits	285	Shared Neighborhood Hits	22
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

CD008_HUMAN
NC score	0.041278 (rank : 390)	θ value	0.813845 (rank : 222)
Query Neighborhood Hits	376	Target Neighborhood Hits	330	Shared Neighborhood Hits	34
SwissProt Accessions	P78312, O43607, P78311, P78313, Q9UEG8	Gene names	C4orf8
Domain Architecture	No domain graphic available
Description	Protein C4orf8 (Protein IT14).

CIR_HUMAN
NC score	0.041058 (rank : 391)	θ value	1.81305 (rank : 251)
Query Neighborhood Hits	376	Target Neighborhood Hits	249	Shared Neighborhood Hits	32
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

CXCC1_HUMAN
NC score	0.039905 (rank : 392)	θ value	1.38821 (rank : 240)
Query Neighborhood Hits	376	Target Neighborhood Hits	143	Shared Neighborhood Hits	15
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

SNIP1_HUMAN
NC score	0.038908 (rank : 393)	θ value	1.81305 (rank : 259)
Query Neighborhood Hits	376	Target Neighborhood Hits	80	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TAD8, Q96SP9, Q9H9T7	Gene names	SNIP1
Domain Architecture
Description	Smad nuclear-interacting protein 1.

STMN1_HUMAN
NC score	0.037972 (rank : 394)	θ value	8.99809 (rank : 370)
Query Neighborhood Hits	376	Target Neighborhood Hits	554	Shared Neighborhood Hits	59
SwissProt Accessions	P16949	Gene names	STMN1, LAP18, OP18
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22).

MY18A_HUMAN
NC score	0.037532 (rank : 395)	θ value	3.0926 (rank : 288)
Query Neighborhood Hits	376	Target Neighborhood Hits	1929	Shared Neighborhood Hits	167
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

DNMT1_HUMAN
NC score	0.037515 (rank : 396)	θ value	5.27518 (rank : 313)
Query Neighborhood Hits	376	Target Neighborhood Hits	401	Shared Neighborhood Hits	55
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

SDCG1_MOUSE
NC score	0.037241 (rank : 397)	θ value	0.163984 (rank : 170)
Query Neighborhood Hits	376	Target Neighborhood Hits	168	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CCP0, Q66JX6, Q8C9R6, Q8CA65, Q8JZT9, Q8R072, Q9CW30, Q9CYB8, Q9D4A9	Gene names	Sdccag1
Domain Architecture
Description	Serologically defined colon cancer antigen 1.

STMN1_MOUSE
NC score	0.037127 (rank : 398)	θ value	8.99809 (rank : 371)
Query Neighborhood Hits	376	Target Neighborhood Hits	560	Shared Neighborhood Hits	59
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

CCD41_MOUSE
NC score	0.035522 (rank : 399)	θ value	0.0736092 (rank : 145)
Query Neighborhood Hits	376	Target Neighborhood Hits	1399	Shared Neighborhood Hits	79
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

AHTF1_MOUSE
NC score	0.035226 (rank : 400)	θ value	1.81305 (rank : 249)
Query Neighborhood Hits	376	Target Neighborhood Hits	176	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CJF7, Q8BVJ5, Q8VD55	Gene names	Ahctf1, Elys
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

HIP1_HUMAN
NC score	0.035077 (rank : 401)	θ value	0.163984 (rank : 164)
Query Neighborhood Hits	376	Target Neighborhood Hits	1016	Shared Neighborhood Hits	63
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

RAI1_MOUSE
NC score	0.034713 (rank : 402)	θ value	4.03905 (rank : 304)
Query Neighborhood Hits	376	Target Neighborhood Hits	344	Shared Neighborhood Hits	23
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

HGS_HUMAN
NC score	0.034621 (rank : 403)	θ value	0.62314 (rank : 214)
Query Neighborhood Hits	376	Target Neighborhood Hits	517	Shared Neighborhood Hits	36
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

ATRX_HUMAN
NC score	0.034597 (rank : 404)	θ value	2.36792 (rank : 260)
Query Neighborhood Hits	376	Target Neighborhood Hits	842	Shared Neighborhood Hits	67
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

MERL_MOUSE
NC score	0.034487 (rank : 405)	θ value	0.813845 (rank : 227)
Query Neighborhood Hits	376	Target Neighborhood Hits	524	Shared Neighborhood Hits	46
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

RAI1_HUMAN
NC score	0.033623 (rank : 406)	θ value	5.27518 (rank : 318)
Query Neighborhood Hits	376	Target Neighborhood Hits	360	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

INCE_MOUSE
NC score	0.032226 (rank : 407)	θ value	1.38821 (rank : 243)
Query Neighborhood Hits	376	Target Neighborhood Hits	903	Shared Neighborhood Hits	64
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

GON4L_HUMAN
NC score	0.032193 (rank : 408)	θ value	4.03905 (rank : 301)
Query Neighborhood Hits	376	Target Neighborhood Hits	555	Shared Neighborhood Hits	44
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

MERL_HUMAN
NC score	0.032027 (rank : 409)	θ value	1.38821 (rank : 245)
Query Neighborhood Hits	376	Target Neighborhood Hits	532	Shared Neighborhood Hits	47
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

FIP1_HUMAN
NC score	0.031325 (rank : 410)	θ value	3.0926 (rank : 284)
Query Neighborhood Hits	376	Target Neighborhood Hits	118	Shared Neighborhood Hits	25
SwissProt Accessions	Q6UN15, Q499Y4, Q49AU3, Q7Z608, Q8WVN3, Q96F80, Q9H077	Gene names	FIP1L1, FIP1, RHE
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1) (Factor interacting with PAP) (hFip1) (Rearranged in hypereosinophilia).

INCE_HUMAN
NC score	0.030838 (rank : 411)	θ value	1.38821 (rank : 242)
Query Neighborhood Hits	376	Target Neighborhood Hits	978	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

HAP1_MOUSE
NC score	0.030422 (rank : 412)	θ value	0.279714 (rank : 186)
Query Neighborhood Hits	376	Target Neighborhood Hits	388	Shared Neighborhood Hits	28
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

CDC37_HUMAN
NC score	0.030023 (rank : 413)	θ value	5.27518 (rank : 310)
Query Neighborhood Hits	376	Target Neighborhood Hits	506	Shared Neighborhood Hits	50
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

PRP4B_HUMAN
NC score	0.029763 (rank : 414)	θ value	0.0252991 (rank : 125)
Query Neighborhood Hits	376	Target Neighborhood Hits	1030	Shared Neighborhood Hits	54
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

MAST3_HUMAN
NC score	0.029672 (rank : 415)	θ value	8.99809 (rank : 360)
Query Neighborhood Hits	376	Target Neighborhood Hits	1128	Shared Neighborhood Hits	88
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

FIP1_MOUSE
NC score	0.029427 (rank : 416)	θ value	3.0926 (rank : 285)
Query Neighborhood Hits	376	Target Neighborhood Hits	120	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D824, Q8BWX7, Q99LH0, Q9DBB2	Gene names	Fip1l1
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1).

RUFY2_MOUSE
NC score	0.029242 (rank : 417)	θ value	1.06291 (rank : 239)
Query Neighborhood Hits	376	Target Neighborhood Hits	820	Shared Neighborhood Hits	43
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

SAFB2_HUMAN
NC score	0.029195 (rank : 418)	θ value	0.163984 (rank : 169)
Query Neighborhood Hits	376	Target Neighborhood Hits	720	Shared Neighborhood Hits	46
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

CCNL1_MOUSE
NC score	0.028955 (rank : 419)	θ value	4.03905 (rank : 298)
Query Neighborhood Hits	376	Target Neighborhood Hits	71	Shared Neighborhood Hits	19
SwissProt Accessions	Q52KE7, Q8BQ75, Q8R5H9, Q922K0, Q9CSZ3, Q9WV44	Gene names	Ccnl1, Ania6a, Ccn1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L) (Cyclin Ania-6a).

T22D2_HUMAN
NC score	0.028562 (rank : 420)	θ value	4.03905 (rank : 306)
Query Neighborhood Hits	376	Target Neighborhood Hits	250	Shared Neighborhood Hits	14
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

PCNT_HUMAN
NC score	0.028375 (rank : 421)	θ value	6.88961 (rank : 340)
Query Neighborhood Hits	376	Target Neighborhood Hits	1551	Shared Neighborhood Hits	84
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

EEA1_HUMAN
NC score	0.028332 (rank : 422)	θ value	0.47712 (rank : 203)
Query Neighborhood Hits	376	Target Neighborhood Hits	1796	Shared Neighborhood Hits	81
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

CCNL1_HUMAN
NC score	0.028255 (rank : 423)	θ value	6.88961 (rank : 324)
Query Neighborhood Hits	376	Target Neighborhood Hits	79	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UK58, Q6NVY9, Q6UWS7, Q8NI48, Q96QT0, Q9NZF3	Gene names	CCNL1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L).

MYST4_HUMAN
NC score	0.027972 (rank : 424)	θ value	5.27518 (rank : 315)
Query Neighborhood Hits	376	Target Neighborhood Hits	671	Shared Neighborhood Hits	52
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

MYST4_MOUSE
NC score	0.027689 (rank : 425)	θ value	2.36792 (rank : 271)
Query Neighborhood Hits	376	Target Neighborhood Hits	416	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

CDSN_MOUSE
NC score	0.026789 (rank : 426)	θ value	4.03905 (rank : 300)
Query Neighborhood Hits	376	Target Neighborhood Hits	131	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TPC1	Gene names	Cdsn
Domain Architecture	No domain graphic available
Description	Corneodesmosin precursor.

PEPL_MOUSE
NC score	0.025914 (rank : 427)	θ value	0.47712 (rank : 210)
Query Neighborhood Hits	376	Target Neighborhood Hits	1105	Shared Neighborhood Hits	66
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

PRP4B_MOUSE
NC score	0.025743 (rank : 428)	θ value	0.47712 (rank : 211)
Query Neighborhood Hits	376	Target Neighborhood Hits	1040	Shared Neighborhood Hits	58
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

EEA1_MOUSE
NC score	0.025710 (rank : 429)	θ value	1.06291 (rank : 231)
Query Neighborhood Hits	376	Target Neighborhood Hits	1637	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

TPR_HUMAN
NC score	0.025698 (rank : 430)	θ value	8.99809 (rank : 373)
Query Neighborhood Hits	376	Target Neighborhood Hits	1921	Shared Neighborhood Hits	97
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

RAD50_HUMAN
NC score	0.025547 (rank : 431)	θ value	1.06291 (rank : 238)
Query Neighborhood Hits	376	Target Neighborhood Hits	1317	Shared Neighborhood Hits	70
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

RUFY2_HUMAN
NC score	0.025460 (rank : 432)	θ value	3.0926 (rank : 291)
Query Neighborhood Hits	376	Target Neighborhood Hits	1208	Shared Neighborhood Hits	64
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

GOGA4_MOUSE
NC score	0.025208 (rank : 433)	θ value	1.38821 (rank : 241)
Query Neighborhood Hits	376	Target Neighborhood Hits	1939	Shared Neighborhood Hits	96
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

TIAM1_MOUSE
NC score	0.024581 (rank : 434)	θ value	5.27518 (rank : 319)
Query Neighborhood Hits	376	Target Neighborhood Hits	205	Shared Neighborhood Hits	32
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

SCG1_MOUSE
NC score	0.023820 (rank : 435)	θ value	8.99809 (rank : 367)
Query Neighborhood Hits	376	Target Neighborhood Hits	163	Shared Neighborhood Hits	21
SwissProt Accessions	P16014	Gene names	Chgb, Scg-1, Scg1
Domain Architecture
Description	Secretogranin-1 precursor (Secretogranin I) (SgI) (Chromogranin B) (CgB).

SFRS7_HUMAN
NC score	0.023438 (rank : 436)	θ value	6.88961 (rank : 342)
Query Neighborhood Hits	376	Target Neighborhood Hits	191	Shared Neighborhood Hits	18
SwissProt Accessions	Q16629	Gene names	SFRS7
Domain Architecture
Description	Splicing factor, arginine/serine-rich 7 (Splicing factor 9G8).

CMGA_MOUSE
NC score	0.022882 (rank : 437)	θ value	8.99809 (rank : 352)
Query Neighborhood Hits	376	Target Neighborhood Hits	172	Shared Neighborhood Hits	28
SwissProt Accessions	P26339	Gene names	Chga
Domain Architecture
Description	Chromogranin A precursor (CgA) [Contains: Pancreastatin; Beta-granin; WE-14].

CHD9_MOUSE
NC score	0.022815 (rank : 438)	θ value	8.99809 (rank : 351)
Query Neighborhood Hits	376	Target Neighborhood Hits	427	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

CN037_MOUSE
NC score	0.021883 (rank : 439)	θ value	3.0926 (rank : 281)
Query Neighborhood Hits	376	Target Neighborhood Hits	179	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

G45IP_MOUSE
NC score	0.021459 (rank : 440)	θ value	6.88961 (rank : 331)
Query Neighborhood Hits	376	Target Neighborhood Hits	68	Shared Neighborhood Hits	12
SwissProt Accessions	Q9CR59, Q8BT05	Gene names	Gadd45gip1
Domain Architecture	No domain graphic available
Description	Growth arrest and DNA-damage-inducible proteins-interacting protein 1.

RPGR1_HUMAN
NC score	0.021418 (rank : 441)	θ value	8.99809 (rank : 366)
Query Neighborhood Hits	376	Target Neighborhood Hits	578	Shared Neighborhood Hits	42
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

HMMR_MOUSE
NC score	0.021277 (rank : 442)	θ value	1.06291 (rank : 234)
Query Neighborhood Hits	376	Target Neighborhood Hits	1178	Shared Neighborhood Hits	62
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

LRC49_HUMAN
NC score	0.020890 (rank : 443)	θ value	0.813845 (rank : 226)
Query Neighborhood Hits	376	Target Neighborhood Hits	210	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IUZ0, Q9NXM6	Gene names	LRRC49
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 49 (Tubulin polyglutamylase complex subunit 4) (PGs4).

FMR1_MOUSE
NC score	0.020718 (rank : 444)	θ value	0.47712 (rank : 204)
Query Neighborhood Hits	376	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	P35922	Gene names	Fmr1, Fmr-1
Domain Architecture
Description	Fragile X mental retardation protein 1 homolog (Protein FMR-1) (FMRP) (mFmr1p).

NIN_HUMAN
NC score	0.020468 (rank : 445)	θ value	8.99809 (rank : 362)
Query Neighborhood Hits	376	Target Neighborhood Hits	1416	Shared Neighborhood Hits	73
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

JHD1B_MOUSE
NC score	0.019668 (rank : 446)	θ value	0.47712 (rank : 207)
Query Neighborhood Hits	376	Target Neighborhood Hits	214	Shared Neighborhood Hits	25
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

CCD93_HUMAN
NC score	0.019261 (rank : 447)	θ value	5.27518 (rank : 309)
Query Neighborhood Hits	376	Target Neighborhood Hits	600	Shared Neighborhood Hits	40
SwissProt Accessions	Q567U6, Q4LE78, Q53TJ2, Q8TBX5, Q9H6R5, Q9NV15	Gene names	CCDC93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

CROCC_HUMAN
NC score	0.019239 (rank : 448)	θ value	6.88961 (rank : 328)
Query Neighborhood Hits	376	Target Neighborhood Hits	1409	Shared Neighborhood Hits	81
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

EP400_MOUSE
NC score	0.019217 (rank : 449)	θ value	3.0926 (rank : 283)
Query Neighborhood Hits	376	Target Neighborhood Hits	592	Shared Neighborhood Hits	37
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

HMMR_HUMAN
NC score	0.019148 (rank : 450)	θ value	6.88961 (rank : 336)
Query Neighborhood Hits	376	Target Neighborhood Hits	1082	Shared Neighborhood Hits	54
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

MGRN1_HUMAN
NC score	0.018999 (rank : 451)	θ value	2.36792 (rank : 270)
Query Neighborhood Hits	376	Target Neighborhood Hits	192	Shared Neighborhood Hits	12
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

BRE1A_HUMAN
NC score	0.018002 (rank : 452)	θ value	6.88961 (rank : 322)
Query Neighborhood Hits	376	Target Neighborhood Hits	1071	Shared Neighborhood Hits	65
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

LRC49_MOUSE
NC score	0.017800 (rank : 453)	θ value	4.03905 (rank : 302)
Query Neighborhood Hits	376	Target Neighborhood Hits	230	Shared Neighborhood Hits	7
SwissProt Accessions	Q91YK0, Q8C3S4, Q8C7T7	Gene names	Lrrc49
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 49 (Tubulin polyglutamylase complex subunit 4) (PGs4) (p79).

FMN2_HUMAN
NC score	0.017206 (rank : 454)	θ value	6.88961 (rank : 330)
Query Neighborhood Hits	376	Target Neighborhood Hits	484	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

MKRN3_HUMAN
NC score	0.016617 (rank : 455)	θ value	3.0926 (rank : 287)
Query Neighborhood Hits	376	Target Neighborhood Hits	165	Shared Neighborhood Hits	9
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

CD2L1_MOUSE
NC score	0.016213 (rank : 456)	θ value	4.03905 (rank : 299)
Query Neighborhood Hits	376	Target Neighborhood Hits	1463	Shared Neighborhood Hits	77
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

TRI40_HUMAN
NC score	0.015522 (rank : 457)	θ value	3.0926 (rank : 295)
Query Neighborhood Hits	376	Target Neighborhood Hits	279	Shared Neighborhood Hits	15
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

CD2L1_HUMAN
NC score	0.015112 (rank : 458)	θ value	6.88961 (rank : 325)
Query Neighborhood Hits	376	Target Neighborhood Hits	1467	Shared Neighborhood Hits	74
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

M4K4_HUMAN
NC score	0.014567 (rank : 459)	θ value	2.36792 (rank : 269)
Query Neighborhood Hits	376	Target Neighborhood Hits	1589	Shared Neighborhood Hits	75
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MINK1_MOUSE
NC score	0.013718 (rank : 460)	θ value	3.0926 (rank : 286)
Query Neighborhood Hits	376	Target Neighborhood Hits	1451	Shared Neighborhood Hits	66
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

LPP_HUMAN
NC score	0.013683 (rank : 461)	θ value	8.99809 (rank : 358)
Query Neighborhood Hits	376	Target Neighborhood Hits	775	Shared Neighborhood Hits	37
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

ZFYV9_HUMAN
NC score	0.013641 (rank : 462)	θ value	8.99809 (rank : 375)
Query Neighborhood Hits	376	Target Neighborhood Hits	134	Shared Neighborhood Hits	11
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

JPH2_MOUSE
NC score	0.013451 (rank : 463)	θ value	5.27518 (rank : 314)
Query Neighborhood Hits	376	Target Neighborhood Hits	279	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

ARFG3_MOUSE
NC score	0.013376 (rank : 464)	θ value	4.03905 (rank : 297)
Query Neighborhood Hits	376	Target Neighborhood Hits	80	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

DJBP_MOUSE
NC score	0.012137 (rank : 465)	θ value	5.27518 (rank : 312)
Query Neighborhood Hits	376	Target Neighborhood Hits	152	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P1E8, Q5DTV8, Q6PGK8, Q9D2D8	Gene names	Djbp, Kiaa1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein.

MAML3_HUMAN
NC score	0.011743 (rank : 466)	θ value	8.99809 (rank : 359)
Query Neighborhood Hits	376	Target Neighborhood Hits	323	Shared Neighborhood Hits	15
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

NCOA1_HUMAN
NC score	0.011135 (rank : 467)	θ value	5.27518 (rank : 316)
Query Neighborhood Hits	376	Target Neighborhood Hits	198	Shared Neighborhood Hits	17
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

ILDR1_HUMAN
NC score	0.010653 (rank : 468)	θ value	6.88961 (rank : 337)
Query Neighborhood Hits	376	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q86SU0, Q6ZP61, Q7Z578	Gene names	ILDR1
Domain Architecture	No domain graphic available
Description	Immunoglobulin-like domain-containing receptor 1 precursor.

BRAF1_HUMAN
NC score	0.010619 (rank : 469)	θ value	6.88961 (rank : 321)
Query Neighborhood Hits	376	Target Neighborhood Hits	883	Shared Neighborhood Hits	21
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

SC24D_HUMAN
NC score	0.010384 (rank : 470)	θ value	6.88961 (rank : 341)
Query Neighborhood Hits	376	Target Neighborhood Hits	173	Shared Neighborhood Hits	8
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

ANR38_MOUSE
NC score	0.010179 (rank : 471)	θ value	4.03905 (rank : 296)
Query Neighborhood Hits	376	Target Neighborhood Hits	512	Shared Neighborhood Hits	32
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

GCM2_HUMAN
NC score	0.010065 (rank : 472)	θ value	6.88961 (rank : 332)
Query Neighborhood Hits	376	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	O75603	Gene names	GCM2, GCMB
Domain Architecture
Description	Chorion-specific transcription factor GCMb (Glial cells missing homolog 2) (GCM motif protein 2) (hGCMb).

CLC4F_MOUSE
NC score	0.009385 (rank : 473)	θ value	2.36792 (rank : 262)
Query Neighborhood Hits	376	Target Neighborhood Hits	572	Shared Neighborhood Hits	27
SwissProt Accessions	P70194, Q8BLZ8	Gene names	Clec4f, Clecsf13, Kclr
Domain Architecture
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13) (Kupffer cell receptor).

PRDM8_MOUSE
NC score	0.009193 (rank : 474)	θ value	5.27518 (rank : 317)
Query Neighborhood Hits	376	Target Neighborhood Hits	176	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BZ97	Gene names	Prdm8
Domain Architecture	No domain graphic available
Description	PR domain zinc finger protein 8 (PR domain-containing protein 8).

LIRB2_HUMAN
NC score	0.009024 (rank : 475)	θ value	2.36792 (rank : 268)
Query Neighborhood Hits	376	Target Neighborhood Hits	103	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N423, O75017, Q8NHJ7, Q8NHJ8	Gene names	LILRB2, ILT4, LIR2, MIR10
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 2 precursor (Leukocyte immunoglobulin-like receptor 2) (LIR-2) (Immunoglobulin- like transcript 4) (ILT-4) (Monocyte/macrophage immunoglobulin-like receptor 10) (MIR-10) (CD85d antigen).

SNX17_HUMAN
NC score	0.007835 (rank : 476)	θ value	8.99809 (rank : 369)
Query Neighborhood Hits	376	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q15036, Q53HN7, Q6IAS3	Gene names	SNX17, KIAA0064
Domain Architecture
Description	Sorting nexin-17.

CBX8_HUMAN
NC score	0.007763 (rank : 477)	θ value	8.99809 (rank : 350)
Query Neighborhood Hits	376	Target Neighborhood Hits	67	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HC52, Q96H39, Q9NR07	Gene names	CBX8, PC3, RC1
Domain Architecture
Description	Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (hPc3) (Rectachrome 1).

HDA10_HUMAN
NC score	0.007534 (rank : 478)	θ value	8.99809 (rank : 354)
Query Neighborhood Hits	376	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	Q969S8, Q6STF9, Q96P77, Q96P78, Q9H028, Q9UGX1, Q9UGX2	Gene names	HDAC10
Domain Architecture
Description	Histone deacetylase 10 (HD10).

STX7_MOUSE
NC score	0.007491 (rank : 479)	θ value	8.99809 (rank : 372)
Query Neighborhood Hits	376	Target Neighborhood Hits	131	Shared Neighborhood Hits	14
SwissProt Accessions	O70439	Gene names	Stx7, Syn7
Domain Architecture
Description	Syntaxin-7.

DDX23_HUMAN
NC score	0.006962 (rank : 480)	θ value	3.0926 (rank : 282)
Query Neighborhood Hits	376	Target Neighborhood Hits	486	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

FBXW7_HUMAN
NC score	0.006811 (rank : 481)	θ value	0.62314 (rank : 212)
Query Neighborhood Hits	376	Target Neighborhood Hits	433	Shared Neighborhood Hits	14
SwissProt Accessions	Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6	Gene names	FBXW7, FBW7, FBX30, SEL10
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10).

CDS1_HUMAN
NC score	0.006389 (rank : 482)	θ value	6.88961 (rank : 326)
Query Neighborhood Hits	376	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q92903, O00163	Gene names	CDS1, CDS
Domain Architecture
Description	Phosphatidate cytidylyltransferase 1 (EC 2.7.7.41) (CDP-diglyceride synthetase 1) (CDP-diglyceride pyrophosphorylase 1) (CDP- diacylglycerol synthase 1) (CDS 1) (CTP:phosphatidate cytidylyltransferase 1) (CDP-DAG synthase 1) (CDP-DG synthetase 1).

LIRB1_HUMAN
NC score	0.005908 (rank : 483)	θ value	6.88961 (rank : 339)
Query Neighborhood Hits	376	Target Neighborhood Hits	116	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NHL6, O75024, O75025, Q8NHJ9, Q8NHK0	Gene names	LILRB1, ILT2, LIR1, MIR7
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 1 precursor (Leukocyte immunoglobulin-like receptor 1) (LIR-1) (Immunoglobulin- like transcript 2) (ILT-2) (Monocyte/macrophage immunoglobulin-like receptor 7) (MIR-7) (CD85j antigen).

PAX1_MOUSE
NC score	0.005139 (rank : 484)	θ value	4.03905 (rank : 303)
Query Neighborhood Hits	376	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	P09084, Q9R2B1	Gene names	Pax1, Pax-1
Domain Architecture
Description	Paired box protein Pax-1.

CAC1A_MOUSE
NC score	0.005100 (rank : 485)	θ value	6.88961 (rank : 323)
Query Neighborhood Hits	376	Target Neighborhood Hits	267	Shared Neighborhood Hits	26
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

VDR_HUMAN
NC score	0.004916 (rank : 486)	θ value	2.36792 (rank : 277)
Query Neighborhood Hits	376	Target Neighborhood Hits	112	Shared Neighborhood Hits	4
SwissProt Accessions	P11473	Gene names	VDR, NR1I1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

WDR20_HUMAN
NC score	0.004811 (rank : 487)	θ value	6.88961 (rank : 346)
Query Neighborhood Hits	376	Target Neighborhood Hits	249	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TBZ3, Q8WXX2, Q9UF86	Gene names	WDR20
Domain Architecture
Description	WD repeat protein 20 (DMR protein).

RNF19_MOUSE
NC score	0.004688 (rank : 488)	θ value	8.99809 (rank : 365)
Query Neighborhood Hits	376	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

ZN452_HUMAN
NC score	0.003606 (rank : 489)	θ value	8.99809 (rank : 376)
Query Neighborhood Hits	376	Target Neighborhood Hits	139	Shared Neighborhood Hits	7
SwissProt Accessions	Q6R2W3, Q2NKL9, Q5SRJ3, Q8TCN2, Q96PW3	Gene names	ZNF452, KIAA1925
Domain Architecture	No domain graphic available
Description	Protein ZNF452.

CSPG2_MOUSE
NC score	0.003361 (rank : 490)	θ value	5.27518 (rank : 311)
Query Neighborhood Hits	376	Target Neighborhood Hits	711	Shared Neighborhood Hits	22
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

LRP2_HUMAN
NC score	0.002287 (rank : 491)	θ value	1.06291 (rank : 236)
Query Neighborhood Hits	376	Target Neighborhood Hits	573	Shared Neighborhood Hits	6
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

ACHA4_HUMAN
NC score	-0.000091 (rank : 492)	θ value	8.99809 (rank : 347)
Query Neighborhood Hits	376	Target Neighborhood Hits	131	Shared Neighborhood Hits	5
SwissProt Accessions	P43681, Q4JGR7	Gene names	CHRNA4, NACRA4
Domain Architecture
Description	Neuronal acetylcholine receptor protein subunit alpha-4 precursor.

HME1_MOUSE
NC score	-0.003013 (rank : 493)	θ value	8.99809 (rank : 355)
Query Neighborhood Hits	376	Target Neighborhood Hits	397	Shared Neighborhood Hits	7
SwissProt Accessions	P09065	Gene names	En1, En-1
Domain Architecture
Description	Homeobox protein engrailed-1 (Mo-En-1).

EVI1_HUMAN
NC score	-0.005292 (rank : 494)	θ value	1.81305 (rank : 253)
Query Neighborhood Hits	376	Target Neighborhood Hits	924	Shared Neighborhood Hits	18
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.

ZFP37_MOUSE
NC score	-0.006068 (rank : 495)	θ value	8.99809 (rank : 374)
Query Neighborhood Hits	376	Target Neighborhood Hits	906	Shared Neighborhood Hits	37
SwissProt Accessions	P17141, Q62514	Gene names	Zfp37, Zfp-37
Domain Architecture
Description	Zinc finger protein 37 (Zfp-37) (Male germ cell-specific zinc finger protein).

ZBT37_HUMAN
NC score	-0.007522 (rank : 496)	θ value	4.03905 (rank : 307)
Query Neighborhood Hits	376	Target Neighborhood Hits	815	Shared Neighborhood Hits	8
SwissProt Accessions	Q5TC79, Q5TC80, Q96M87, Q9BQ88	Gene names	ZBTB37
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 37.

ZN212_HUMAN
NC score	-0.007551 (rank : 497)	θ value	5.27518 (rank : 320)
Query Neighborhood Hits	376	Target Neighborhood Hits	699	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UDV6, Q13396, Q8N664	Gene names	ZNF212, ZNFC150
Domain Architecture	No domain graphic available
Description	Zinc finger protein 212 (Zinc finger protein C2H2-150).

ZN366_HUMAN
NC score	-0.007757 (rank : 498)	θ value	2.36792 (rank : 278)
Query Neighborhood Hits	376	Target Neighborhood Hits	732	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N895, Q7RTV4	Gene names	ZNF366
Domain Architecture	No domain graphic available
Description	Zinc finger protein 366.