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Network neighborhood for query Sequence : YAP1_MOUSE

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YAP1_MOUSE
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

YAP1_HUMAN
θ value	0 (rank : 1)	NC score	0.936833 (rank : 2)
Query Neighborhood Hits	96	Target Neighborhood Hits	173	Shared Neighborhood Hits	72
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

YAP1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	96	Target Neighborhood Hits	96	Shared Neighborhood Hits	96
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

WWTR1_HUMAN
θ value	2.24094e-75 (rank : 3)	NC score	0.903264 (rank : 4)
Query Neighborhood Hits	96	Target Neighborhood Hits	76	Shared Neighborhood Hits	45
SwissProt Accessions	Q9GZV5, Q8N3P2, Q9Y3W6	Gene names	WWTR1, TAZ
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

WWTR1_MOUSE
θ value	4.68348e-65 (rank : 4)	NC score	0.904695 (rank : 3)
Query Neighborhood Hits	96	Target Neighborhood Hits	54	Shared Neighborhood Hits	41
SwissProt Accessions	Q9EPK5, Q99KI4	Gene names	Wwtr1, Taz
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

NEDD4_HUMAN
θ value	8.10077e-17 (rank : 5)	NC score	0.520319 (rank : 17)
Query Neighborhood Hits	96	Target Neighborhood Hits	214	Shared Neighborhood Hits	51
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

NED4L_MOUSE
θ value	1.80466e-16 (rank : 6)	NC score	0.516571 (rank : 18)
Query Neighborhood Hits	96	Target Neighborhood Hits	231	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_HUMAN
θ value	4.02038e-16 (rank : 7)	NC score	0.515067 (rank : 20)
Query Neighborhood Hits	96	Target Neighborhood Hits	238	Shared Neighborhood Hits	55
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

WWP1_MOUSE
θ value	2.60593e-15 (rank : 8)	NC score	0.563416 (rank : 7)
Query Neighborhood Hits	96	Target Neighborhood Hits	138	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

NEDD4_MOUSE
θ value	1.68911e-14 (rank : 9)	NC score	0.516083 (rank : 19)
Query Neighborhood Hits	96	Target Neighborhood Hits	212	Shared Neighborhood Hits	55
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

ITCH_HUMAN
θ value	2.20605e-14 (rank : 10)	NC score	0.548078 (rank : 12)
Query Neighborhood Hits	96	Target Neighborhood Hits	162	Shared Neighborhood Hits	50
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

ITCH_MOUSE
θ value	8.38298e-14 (rank : 11)	NC score	0.550944 (rank : 11)
Query Neighborhood Hits	96	Target Neighborhood Hits	127	Shared Neighborhood Hits	49
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

WWP1_HUMAN
θ value	8.38298e-14 (rank : 12)	NC score	0.553415 (rank : 10)
Query Neighborhood Hits	96	Target Neighborhood Hits	262	Shared Neighborhood Hits	55
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

WWP2_HUMAN
θ value	1.86753e-13 (rank : 13)	NC score	0.556640 (rank : 9)
Query Neighborhood Hits	96	Target Neighborhood Hits	177	Shared Neighborhood Hits	56
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

WWP2_MOUSE
θ value	1.86753e-13 (rank : 14)	NC score	0.557338 (rank : 8)
Query Neighborhood Hits	96	Target Neighborhood Hits	118	Shared Neighborhood Hits	54
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

SMUF1_HUMAN
θ value	9.26847e-13 (rank : 15)	NC score	0.514704 (rank : 21)
Query Neighborhood Hits	96	Target Neighborhood Hits	135	Shared Neighborhood Hits	39
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

MAGI1_MOUSE
θ value	2.0648e-12 (rank : 16)	NC score	0.401988 (rank : 28)
Query Neighborhood Hits	96	Target Neighborhood Hits	403	Shared Neighborhood Hits	52
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

SMUF2_HUMAN
θ value	2.0648e-12 (rank : 17)	NC score	0.529131 (rank : 15)
Query Neighborhood Hits	96	Target Neighborhood Hits	142	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

SMUF1_MOUSE
θ value	3.52202e-12 (rank : 18)	NC score	0.521582 (rank : 16)
Query Neighborhood Hits	96	Target Neighborhood Hits	142	Shared Neighborhood Hits	40
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

MAGI1_HUMAN
θ value	4.59992e-12 (rank : 19)	NC score	0.402540 (rank : 27)
Query Neighborhood Hits	96	Target Neighborhood Hits	388	Shared Neighborhood Hits	52
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

WWC1_HUMAN
θ value	6.00763e-12 (rank : 20)	NC score	0.538692 (rank : 13)
Query Neighborhood Hits	96	Target Neighborhood Hits	290	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

WWC1_MOUSE
θ value	6.00763e-12 (rank : 21)	NC score	0.534592 (rank : 14)
Query Neighborhood Hits	96	Target Neighborhood Hits	290	Shared Neighborhood Hits	39
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

WWOX_HUMAN
θ value	1.74796e-11 (rank : 22)	NC score	0.458815 (rank : 22)
Query Neighborhood Hits	96	Target Neighborhood Hits	115	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NZC7, Q5MYT5, Q96KM3, Q96RF2, Q9BTT8, Q9NPC9, Q9NRF4, Q9NRF5, Q9NRF6, Q9NRK1, Q9NZC5	Gene names	WWOX, FOR, WOX1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase).

WWOX_MOUSE
θ value	1.74796e-11 (rank : 23)	NC score	0.454873 (rank : 23)
Query Neighborhood Hits	96	Target Neighborhood Hits	118	Shared Neighborhood Hits	48
SwissProt Accessions	Q91WL8, Q8C8J6, Q920Y2, Q9D2B3, Q9D339, Q9JLF5	Gene names	Wwox, Wox1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-).

MAGI2_MOUSE
θ value	8.67504e-11 (rank : 24)	NC score	0.425078 (rank : 25)
Query Neighborhood Hits	96	Target Neighborhood Hits	370	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

MAGI2_HUMAN
θ value	1.47974e-10 (rank : 25)	NC score	0.415240 (rank : 26)
Query Neighborhood Hits	96	Target Neighborhood Hits	373	Shared Neighborhood Hits	50
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

SAV1_HUMAN
θ value	8.97725e-08 (rank : 26)	NC score	0.605154 (rank : 5)
Query Neighborhood Hits	96	Target Neighborhood Hits	51	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H4B6, Q6IA58, Q9H949, Q9HAK9	Gene names	SAV1, WW45
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (hWW45).

SAV1_MOUSE
θ value	1.53129e-07 (rank : 27)	NC score	0.603615 (rank : 6)
Query Neighborhood Hits	96	Target Neighborhood Hits	48	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VEB2, Q9D9N9, Q9ER46	Gene names	Sav1, Ww45, Wwp3
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (mWW45).

BAG3_MOUSE
θ value	1.43324e-05 (rank : 28)	NC score	0.388871 (rank : 30)
Query Neighborhood Hits	96	Target Neighborhood Hits	513	Shared Neighborhood Hits	56
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

PKHA5_HUMAN
θ value	1.43324e-05 (rank : 29)	NC score	0.315430 (rank : 35)
Query Neighborhood Hits	96	Target Neighborhood Hits	455	Shared Neighborhood Hits	40
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

BAG3_HUMAN
θ value	3.19293e-05 (rank : 30)	NC score	0.433871 (rank : 24)
Query Neighborhood Hits	96	Target Neighborhood Hits	314	Shared Neighborhood Hits	47
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

STXB4_MOUSE
θ value	5.44631e-05 (rank : 31)	NC score	0.272693 (rank : 45)
Query Neighborhood Hits	96	Target Neighborhood Hits	629	Shared Neighborhood Hits	50
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

STXB4_HUMAN
θ value	0.000158464 (rank : 32)	NC score	0.268794 (rank : 47)
Query Neighborhood Hits	96	Target Neighborhood Hits	616	Shared Neighborhood Hits	50
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

DRP2_HUMAN
θ value	0.00869519 (rank : 33)	NC score	0.149703 (rank : 60)
Query Neighborhood Hits	96	Target Neighborhood Hits	186	Shared Neighborhood Hits	24
SwissProt Accessions	Q13474	Gene names	DRP2
Domain Architecture
Description	Dystrophin-related protein 2.

RHG12_MOUSE
θ value	0.00869519 (rank : 34)	NC score	0.131030 (rank : 62)
Query Neighborhood Hits	96	Target Neighborhood Hits	204	Shared Neighborhood Hits	34
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_HUMAN
θ value	0.0148317 (rank : 35)	NC score	0.115527 (rank : 63)
Query Neighborhood Hits	96	Target Neighborhood Hits	190	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

DMD_HUMAN
θ value	0.0193708 (rank : 36)	NC score	0.077393 (rank : 76)
Query Neighborhood Hits	96	Target Neighborhood Hits	1135	Shared Neighborhood Hits	39
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

DMD_MOUSE
θ value	0.0193708 (rank : 37)	NC score	0.073611 (rank : 78)
Query Neighborhood Hits	96	Target Neighborhood Hits	1111	Shared Neighborhood Hits	39
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

GAS7_MOUSE
θ value	0.0563607 (rank : 38)	NC score	0.270360 (rank : 46)
Query Neighborhood Hits	96	Target Neighborhood Hits	259	Shared Neighborhood Hits	44
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

TCRG1_HUMAN
θ value	0.0563607 (rank : 39)	NC score	0.103637 (rank : 66)
Query Neighborhood Hits	96	Target Neighborhood Hits	929	Shared Neighborhood Hits	49
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

ZEP2_HUMAN
θ value	0.0563607 (rank : 40)	NC score	0.019384 (rank : 131)
Query Neighborhood Hits	96	Target Neighborhood Hits	937	Shared Neighborhood Hits	11
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

OGFR_HUMAN
θ value	0.0736092 (rank : 41)	NC score	0.039371 (rank : 114)
Query Neighborhood Hits	96	Target Neighborhood Hits	1582	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PRP40_HUMAN
θ value	0.0736092 (rank : 42)	NC score	0.200862 (rank : 56)
Query Neighborhood Hits	96	Target Neighborhood Hits	442	Shared Neighborhood Hits	43
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

PRP40_MOUSE
θ value	0.0736092 (rank : 43)	NC score	0.194877 (rank : 58)
Query Neighborhood Hits	96	Target Neighborhood Hits	447	Shared Neighborhood Hits	41
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

UTRO_HUMAN
θ value	0.0736092 (rank : 44)	NC score	0.069585 (rank : 79)
Query Neighborhood Hits	96	Target Neighborhood Hits	960	Shared Neighborhood Hits	39
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

PIN1_MOUSE
θ value	0.0961366 (rank : 45)	NC score	0.372003 (rank : 31)
Query Neighborhood Hits	96	Target Neighborhood Hits	60	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QUR7, Q543B3	Gene names	Pin1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

TCRG1_MOUSE
θ value	0.125558 (rank : 46)	NC score	0.102268 (rank : 67)
Query Neighborhood Hits	96	Target Neighborhood Hits	947	Shared Neighborhood Hits	50
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

GAS7_HUMAN
θ value	0.163984 (rank : 47)	NC score	0.263430 (rank : 48)
Query Neighborhood Hits	96	Target Neighborhood Hits	258	Shared Neighborhood Hits	44
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

PCLO_MOUSE
θ value	0.21417 (rank : 48)	NC score	0.075826 (rank : 77)
Query Neighborhood Hits	96	Target Neighborhood Hits	2275	Shared Neighborhood Hits	59
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

APBB1_HUMAN
θ value	0.365318 (rank : 49)	NC score	0.084609 (rank : 73)
Query Neighborhood Hits	96	Target Neighborhood Hits	62	Shared Neighborhood Hits	19
SwissProt Accessions	O00213, Q96A93	Gene names	APBB1, FE65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

APBB1_MOUSE
θ value	0.365318 (rank : 50)	NC score	0.085122 (rank : 72)
Query Neighborhood Hits	96	Target Neighborhood Hits	75	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QXJ1, O08642, Q3TPU0, Q8BNF4, Q8BSR9	Gene names	Apbb1, Fe65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

PIN1_HUMAN
θ value	0.365318 (rank : 51)	NC score	0.361263 (rank : 32)
Query Neighborhood Hits	96	Target Neighborhood Hits	59	Shared Neighborhood Hits	39
SwissProt Accessions	Q13526	Gene names	PIN1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

SETD2_HUMAN
θ value	0.62314 (rank : 52)	NC score	0.132298 (rank : 61)
Query Neighborhood Hits	96	Target Neighborhood Hits	412	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

TRAIP_HUMAN
θ value	0.62314 (rank : 53)	NC score	0.021771 (rank : 128)
Query Neighborhood Hits	96	Target Neighborhood Hits	780	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

BAZ2A_MOUSE
θ value	0.813845 (rank : 54)	NC score	0.025623 (rank : 125)
Query Neighborhood Hits	96	Target Neighborhood Hits	744	Shared Neighborhood Hits	23
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

TTBK1_HUMAN
θ value	0.813845 (rank : 55)	NC score	0.010200 (rank : 142)
Query Neighborhood Hits	96	Target Neighborhood Hits	1058	Shared Neighborhood Hits	16
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

ZEP1_MOUSE
θ value	0.813845 (rank : 56)	NC score	0.013306 (rank : 138)
Query Neighborhood Hits	96	Target Neighborhood Hits	1063	Shared Neighborhood Hits	20
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

MUC1_HUMAN
θ value	1.06291 (rank : 57)	NC score	0.023266 (rank : 126)
Query Neighborhood Hits	96	Target Neighborhood Hits	975	Shared Neighborhood Hits	27
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

CEL_HUMAN
θ value	1.38821 (rank : 58)	NC score	0.018661 (rank : 132)
Query Neighborhood Hits	96	Target Neighborhood Hits	896	Shared Neighborhood Hits	21
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

ANK2_HUMAN
θ value	1.81305 (rank : 59)	NC score	0.018210 (rank : 134)
Query Neighborhood Hits	96	Target Neighborhood Hits	1615	Shared Neighborhood Hits	42
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

WBP4_MOUSE
θ value	1.81305 (rank : 60)	NC score	0.112659 (rank : 64)
Query Neighborhood Hits	96	Target Neighborhood Hits	100	Shared Neighborhood Hits	30
SwissProt Accessions	Q61048, Q8K1Z9, Q9CS45	Gene names	Wbp4, Fbp21, Fnbp21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

CN152_HUMAN
θ value	2.36792 (rank : 61)	NC score	0.049322 (rank : 112)
Query Neighborhood Hits	96	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N9Y4, Q96GY1	Gene names	C14orf152
Domain Architecture	No domain graphic available
Description	Protein C14orf152.

GRIN1_MOUSE
θ value	2.36792 (rank : 62)	NC score	0.036598 (rank : 117)
Query Neighborhood Hits	96	Target Neighborhood Hits	337	Shared Neighborhood Hits	18
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

NOTC2_HUMAN
θ value	2.36792 (rank : 63)	NC score	0.002985 (rank : 150)
Query Neighborhood Hits	96	Target Neighborhood Hits	1113	Shared Neighborhood Hits	13
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

OGFR_MOUSE
θ value	2.36792 (rank : 64)	NC score	0.030354 (rank : 121)
Query Neighborhood Hits	96	Target Neighborhood Hits	584	Shared Neighborhood Hits	15
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

PI5PA_HUMAN
θ value	2.36792 (rank : 65)	NC score	0.031466 (rank : 120)
Query Neighborhood Hits	96	Target Neighborhood Hits	749	Shared Neighborhood Hits	24
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PIAS4_MOUSE
θ value	2.36792 (rank : 66)	NC score	0.012047 (rank : 139)
Query Neighborhood Hits	96	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JM05, Q8R165	Gene names	Pias4, Piasg
Domain Architecture
Description	Protein inhibitor of activated STAT protein 4 (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma) (PIASy).

ANC1_HUMAN
θ value	3.0926 (rank : 67)	NC score	0.033980 (rank : 118)
Query Neighborhood Hits	96	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H1A4, Q9BSE6, Q9H8D0	Gene names	ANAPC1, TSG24
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Protein Tsg24) (Mitotic checkpoint regulator).

ANC1_MOUSE
θ value	3.0926 (rank : 68)	NC score	0.037165 (rank : 116)
Query Neighborhood Hits	96	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	P53995, Q8BP33, Q8C772	Gene names	Anapc1, Mcpr, Tsg24
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Protein Tsg24) (Mitotic checkpoint regulator).

DGCR8_HUMAN
θ value	3.0926 (rank : 69)	NC score	0.093202 (rank : 70)
Query Neighborhood Hits	96	Target Neighborhood Hits	72	Shared Neighborhood Hits	16
SwissProt Accessions	Q8WYQ5, Q6DCB2, Q6MZE9, Q6Y2L0, Q96G39, Q96GP8, Q9H6L8, Q9H6T7, Q9NRW2	Gene names	DGCR8, C22orf12, DGCRK6
Domain Architecture
Description	DGCR8 protein (DiGeorge syndrome critical region 8).

DGCR8_MOUSE
θ value	3.0926 (rank : 70)	NC score	0.090064 (rank : 71)
Query Neighborhood Hits	96	Target Neighborhood Hits	70	Shared Neighborhood Hits	14
SwissProt Accessions	Q9EQM6	Gene names	Dgcr8
Domain Architecture	No domain graphic available
Description	DGCR8 protein (DiGeorge syndrome critical region 8 homolog) (Gy1).

KIF5C_HUMAN
θ value	3.0926 (rank : 71)	NC score	0.009946 (rank : 143)
Query Neighborhood Hits	96	Target Neighborhood Hits	974	Shared Neighborhood Hits	18
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

KIF5C_MOUSE
θ value	3.0926 (rank : 72)	NC score	0.009231 (rank : 145)
Query Neighborhood Hits	96	Target Neighborhood Hits	1040	Shared Neighborhood Hits	18
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

RGS3_MOUSE
θ value	3.0926 (rank : 73)	NC score	0.032836 (rank : 119)
Query Neighborhood Hits	96	Target Neighborhood Hits	1621	Shared Neighborhood Hits	39
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

DYDC1_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.018533 (rank : 133)
Query Neighborhood Hits	96	Target Neighborhood Hits	142	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WWB3, Q5QP03, Q5QP04, Q6WNP4, Q6ZU87	Gene names	DYDC1, DPY30D1
Domain Architecture	No domain graphic available
Description	DPY30 domain-containing protein 1 (RSD-9).

MDC1_HUMAN
θ value	4.03905 (rank : 75)	NC score	0.040234 (rank : 113)
Query Neighborhood Hits	96	Target Neighborhood Hits	1446	Shared Neighborhood Hits	35
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PAX1_MOUSE
θ value	4.03905 (rank : 76)	NC score	0.015217 (rank : 136)
Query Neighborhood Hits	96	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	P09084, Q9R2B1	Gene names	Pax1, Pax-1
Domain Architecture
Description	Paired box protein Pax-1.

PINL_HUMAN
θ value	4.03905 (rank : 77)	NC score	0.393602 (rank : 29)
Query Neighborhood Hits	96	Target Neighborhood Hits	47	Shared Neighborhood Hits	40
SwissProt Accessions	O15428	Gene names	PIN1L
Domain Architecture
Description	PIN1-like protein.

BSN_HUMAN
θ value	5.27518 (rank : 78)	NC score	0.030240 (rank : 122)
Query Neighborhood Hits	96	Target Neighborhood Hits	1537	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CDC37_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.013976 (rank : 137)
Query Neighborhood Hits	96	Target Neighborhood Hits	506	Shared Neighborhood Hits	11
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

FILA_HUMAN
θ value	5.27518 (rank : 80)	NC score	0.022967 (rank : 127)
Query Neighborhood Hits	96	Target Neighborhood Hits	685	Shared Neighborhood Hits	19
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

MAD3_HUMAN
θ value	5.27518 (rank : 81)	NC score	0.011746 (rank : 141)
Query Neighborhood Hits	96	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3	Gene names	MXD3, MAD3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).

NCOA6_MOUSE
θ value	5.27518 (rank : 82)	NC score	0.027937 (rank : 124)
Query Neighborhood Hits	96	Target Neighborhood Hits	1076	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

SMAD4_MOUSE
θ value	5.27518 (rank : 83)	NC score	0.009919 (rank : 144)
Query Neighborhood Hits	96	Target Neighborhood Hits	101	Shared Neighborhood Hits	4
SwissProt Accessions	P97471, Q9CW56	Gene names	Smad4, Dpc4, Madh4
Domain Architecture
Description	Mothers against decapentaplegic homolog 4 (SMAD 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4 homolog) (Smad4).

WHRN_MOUSE
θ value	5.27518 (rank : 84)	NC score	0.060280 (rank : 82)
Query Neighborhood Hits	96	Target Neighborhood Hits	412	Shared Neighborhood Hits	22
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

K1543_HUMAN
θ value	6.88961 (rank : 85)	NC score	0.021366 (rank : 129)
Query Neighborhood Hits	96	Target Neighborhood Hits	435	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

NEB2_MOUSE
θ value	6.88961 (rank : 86)	NC score	0.039278 (rank : 115)
Query Neighborhood Hits	96	Target Neighborhood Hits	889	Shared Neighborhood Hits	24
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NFH_MOUSE
θ value	6.88961 (rank : 87)	NC score	0.021149 (rank : 130)
Query Neighborhood Hits	96	Target Neighborhood Hits	2247	Shared Neighborhood Hits	43
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

T240L_MOUSE
θ value	6.88961 (rank : 88)	NC score	0.011753 (rank : 140)
Query Neighborhood Hits	96	Target Neighborhood Hits	143	Shared Neighborhood Hits	10
SwissProt Accessions	Q6JPI3, Q3TRF4, Q3UQI8, Q80TM3, Q80WQ0	Gene names	Thrap2, Kiaa1025, Trap240l
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

BAT2_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.028617 (rank : 123)
Query Neighborhood Hits	96	Target Neighborhood Hits	931	Shared Neighborhood Hits	30
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CAC1G_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.004020 (rank : 149)
Query Neighborhood Hits	96	Target Neighborhood Hits	587	Shared Neighborhood Hits	14
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CD2L7_HUMAN
θ value	8.99809 (rank : 91)	NC score	-0.000337 (rank : 151)
Query Neighborhood Hits	96	Target Neighborhood Hits	1275	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

CP135_HUMAN
θ value	8.99809 (rank : 92)	NC score	0.009213 (rank : 146)
Query Neighborhood Hits	96	Target Neighborhood Hits	1290	Shared Neighborhood Hits	26
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

GPTC8_HUMAN
θ value	8.99809 (rank : 93)	NC score	0.016657 (rank : 135)
Query Neighborhood Hits	96	Target Neighborhood Hits	366	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

PER2_MOUSE
θ value	8.99809 (rank : 94)	NC score	0.006641 (rank : 147)
Query Neighborhood Hits	96	Target Neighborhood Hits	325	Shared Neighborhood Hits	8
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

RBM11_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.005762 (rank : 148)
Query Neighborhood Hits	96	Target Neighborhood Hits	149	Shared Neighborhood Hits	2
SwissProt Accessions	P57052	Gene names	RBM11
Domain Architecture
Description	Putative RNA-binding protein 11 (RNA-binding motif protein 11).

ZN232_HUMAN
θ value	8.99809 (rank : 96)	NC score	-0.003568 (rank : 152)
Query Neighborhood Hits	96	Target Neighborhood Hits	754	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UNY5	Gene names	ZNF232, ZSCAN11
Domain Architecture
Description	Zinc finger protein 232 (Zinc finger and SCAN domain-containing protein 11).

APBB2_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.108200 (rank : 65)
Query Neighborhood Hits	96	Target Neighborhood Hits	96	Shared Neighborhood Hits	27
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

APBB2_MOUSE
θ value	θ > 10 (rank : 98)	NC score	0.095418 (rank : 69)
Query Neighborhood Hits	96	Target Neighborhood Hits	88	Shared Neighborhood Hits	24
SwissProt Accessions	Q9DBR4, Q6DFX8	Gene names	Apbb2
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2.

APBB3_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.082548 (rank : 74)
Query Neighborhood Hits	96	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	O95704, Q9NYX6, Q9NYX7, Q9NYX8	Gene names	APBB3, FE65L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 3 (Fe65-like protein 2) (Fe65L2).

APBB3_MOUSE
θ value	θ > 10 (rank : 100)	NC score	0.080661 (rank : 75)
Query Neighborhood Hits	96	Target Neighborhood Hits	32	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R1C9	Gene names	Apbb3
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 3.

DHRSX_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.054792 (rank : 90)
Query Neighborhood Hits	96	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N5I4, Q6UWC7, Q8WUS4, Q96GR8, Q9NTF6	Gene names	DHRSX, CXorf11, DHRS5X
Domain Architecture
Description	Dehydrogenase/reductase SDR family member on chromosome X precursor (EC 1.1.-.-) (DHRSXY).

DOC2A_MOUSE
θ value	θ > 10 (rank : 102)	NC score	0.051477 (rank : 105)
Query Neighborhood Hits	96	Target Neighborhood Hits	140	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

DOC2B_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.052335 (rank : 100)
Query Neighborhood Hits	96	Target Neighborhood Hits	150	Shared Neighborhood Hits	12
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

DOC2B_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.051534 (rank : 104)
Query Neighborhood Hits	96	Target Neighborhood Hits	169	Shared Neighborhood Hits	13
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

EDD1_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.213132 (rank : 53)
Query Neighborhood Hits	96	Target Neighborhood Hits	170	Shared Neighborhood Hits	15
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

EDD1_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.213360 (rank : 52)
Query Neighborhood Hits	96	Target Neighborhood Hits	167	Shared Neighborhood Hits	15
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

FA62A_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.054421 (rank : 92)
Query Neighborhood Hits	96	Target Neighborhood Hits	168	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

FA62A_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.063919 (rank : 80)
Query Neighborhood Hits	96	Target Neighborhood Hits	155	Shared Neighborhood Hits	12
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

HECD1_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.191257 (rank : 59)
Query Neighborhood Hits	96	Target Neighborhood Hits	371	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

HECD2_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.303897 (rank : 39)
Query Neighborhood Hits	96	Target Neighborhood Hits	41	Shared Neighborhood Hits	13
SwissProt Accessions	Q5U5R9, Q5VZ97, Q5VZ99, Q8TCP5	Gene names	HECTD2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

HECD2_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.305534 (rank : 38)
Query Neighborhood Hits	96	Target Neighborhood Hits	38	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CDU6, Q8CBQ9	Gene names	Hectd2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

HECD3_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.210317 (rank : 54)
Query Neighborhood Hits	96	Target Neighborhood Hits	49	Shared Neighborhood Hits	13
SwissProt Accessions	Q5T447, Q5T448, Q9H783	Gene names	HECTD3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HECD3_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.214062 (rank : 51)
Query Neighborhood Hits	96	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q3U487, Q3TN76, Q641P3, Q8BQ74, Q8R1L6	Gene names	Hectd3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HERC2_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.199636 (rank : 57)
Query Neighborhood Hits	96	Target Neighborhood Hits	163	Shared Neighborhood Hits	17
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HERC2_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.201905 (rank : 55)
Query Neighborhood Hits	96	Target Neighborhood Hits	167	Shared Neighborhood Hits	17
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HERC3_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.247833 (rank : 50)
Query Neighborhood Hits	96	Target Neighborhood Hits	62	Shared Neighborhood Hits	13
SwissProt Accessions	Q15034	Gene names	HERC3, KIAA0032
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain protein 3.

HERC5_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.255335 (rank : 49)
Query Neighborhood Hits	96	Target Neighborhood Hits	66	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UII4	Gene names	HERC5, CEB1, CEBP1
Domain Architecture
Description	HECT domain and RCC1-like domain-containing protein 5 (Cyclin-E- binding protein 1).

HUWE1_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.313070 (rank : 37)
Query Neighborhood Hits	96	Target Neighborhood Hits	443	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HUWE1_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.313470 (rank : 36)
Query Neighborhood Hits	96	Target Neighborhood Hits	406	Shared Neighborhood Hits	25
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

INADL_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.050912 (rank : 109)
Query Neighborhood Hits	96	Target Neighborhood Hits	290	Shared Neighborhood Hits	12
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

K0317_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.321087 (rank : 33)
Query Neighborhood Hits	96	Target Neighborhood Hits	46	Shared Neighborhood Hits	13
SwissProt Accessions	O15033, Q7LDY1, Q8IYY9	Gene names	KIAA0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

K0317_MOUSE
θ value	θ > 10 (rank : 122)	NC score	0.320982 (rank : 34)
Query Neighborhood Hits	96	Target Neighborhood Hits	43	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CHG5, Q6P9Q1, Q80YC4, Q8C5W5	Gene names	Kiaa0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

K1849_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.061092 (rank : 81)
Query Neighborhood Hits	96	Target Neighborhood Hits	220	Shared Neighborhood Hits	14
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

K1849_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.054384 (rank : 93)
Query Neighborhood Hits	96	Target Neighborhood Hits	335	Shared Neighborhood Hits	12
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

LIN7B_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.050677 (rank : 110)
Query Neighborhood Hits	96	Target Neighborhood Hits	200	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

LIN7B_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.051467 (rank : 106)
Query Neighborhood Hits	96	Target Neighborhood Hits	200	Shared Neighborhood Hits	9
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

LIN7C_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.052043 (rank : 102)
Query Neighborhood Hits	96	Target Neighborhood Hits	198	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.052043 (rank : 103)
Query Neighborhood Hits	96	Target Neighborhood Hits	198	Shared Neighborhood Hits	9
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

MPDZ_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.054373 (rank : 94)
Query Neighborhood Hits	96	Target Neighborhood Hits	261	Shared Neighborhood Hits	10
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

MPDZ_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.051199 (rank : 107)
Query Neighborhood Hits	96	Target Neighborhood Hits	298	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

PAR3L_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.050204 (rank : 111)
Query Neighborhood Hits	96	Target Neighborhood Hits	297	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

PARD3_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.054497 (rank : 91)
Query Neighborhood Hits	96	Target Neighborhood Hits	312	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

PARD3_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.057142 (rank : 85)
Query Neighborhood Hits	96	Target Neighborhood Hits	290	Shared Neighborhood Hits	12
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

PCLO_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.055992 (rank : 87)
Query Neighborhood Hits	96	Target Neighborhood Hits	2046	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RASL1_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.052508 (rank : 99)
Query Neighborhood Hits	96	Target Neighborhood Hits	142	Shared Neighborhood Hits	8
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

RDH12_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.051039 (rank : 108)
Query Neighborhood Hits	96	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q96NR8, Q8TAW6	Gene names	RDH12
Domain Architecture
Description	Retinol dehydrogenase 12 (EC 1.1.1.-) (All-trans and 9-cis retinol dehydrogenase).

RDH12_MOUSE
θ value	θ > 10 (rank : 137)	NC score	0.052684 (rank : 98)
Query Neighborhood Hits	96	Target Neighborhood Hits	74	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BYK4, Q91WA5, Q9D1Y4	Gene names	Rdh12
Domain Architecture
Description	Retinol dehydrogenase 12 (EC 1.1.1.-).

RDH14_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.052814 (rank : 97)
Query Neighborhood Hits	96	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HBH5	Gene names	RDH14, PAN2
Domain Architecture
Description	Retinol dehydrogenase 14 (EC 1.1.1.-) (Alcohol dehydrogenase PAN2).

RDH14_MOUSE
θ value	θ > 10 (rank : 139)	NC score	0.052212 (rank : 101)
Query Neighborhood Hits	96	Target Neighborhood Hits	74	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ERI6	Gene names	Rdh14
Domain Architecture
Description	Retinol dehydrogenase 14 (EC 1.1.1.-) (Alcohol dehydrogenase PAN2).

RIMS2_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.055267 (rank : 89)
Query Neighborhood Hits	96	Target Neighborhood Hits	342	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
θ value	θ > 10 (rank : 141)	NC score	0.055814 (rank : 88)
Query Neighborhood Hits	96	Target Neighborhood Hits	376	Shared Neighborhood Hits	25
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

SYJ2B_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.054223 (rank : 95)
Query Neighborhood Hits	96	Target Neighborhood Hits	162	Shared Neighborhood Hits	9
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

TRIPC_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.276194 (rank : 44)
Query Neighborhood Hits	96	Target Neighborhood Hits	319	Shared Neighborhood Hits	25
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

UBE3A_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.296582 (rank : 40)
Query Neighborhood Hits	96	Target Neighborhood Hits	49	Shared Neighborhood Hits	13
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

UBE3A_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.292702 (rank : 42)
Query Neighborhood Hits	96	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	O08759, P97482	Gene names	Ube3a
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic protein- associated protein E6-AP).

UBE3C_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.293542 (rank : 41)
Query Neighborhood Hits	96	Target Neighborhood Hits	51	Shared Neighborhood Hits	13
SwissProt Accessions	Q15386, Q8TC15, Q96CR4, Q9UDU3	Gene names	UBE3C, KIAA0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

UBE3C_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.292528 (rank : 43)
Query Neighborhood Hits	96	Target Neighborhood Hits	48	Shared Neighborhood Hits	13
SwissProt Accessions	Q80U95, Q8BQZ6, Q8C7W6, Q8CDJ1, Q8VDL5	Gene names	Ube3c, Kiaa0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

UN13A_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.056995 (rank : 86)
Query Neighborhood Hits	96	Target Neighborhood Hits	285	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

UN13B_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.059345 (rank : 84)
Query Neighborhood Hits	96	Target Neighborhood Hits	217	Shared Neighborhood Hits	10
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13B_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.059510 (rank : 83)
Query Neighborhood Hits	96	Target Neighborhood Hits	210	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

WBP4_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.053303 (rank : 96)
Query Neighborhood Hits	96	Target Neighborhood Hits	86	Shared Neighborhood Hits	20
SwissProt Accessions	O75554	Gene names	WBP4, FBP21, FNBP21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

WWC3_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.101402 (rank : 68)
Query Neighborhood Hits	96	Target Neighborhood Hits	193	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ULE0, Q659C1, Q9BTQ1	Gene names	WWC3, KIAA1280
Domain Architecture	No domain graphic available
Description	WWC family member 3.

Hits sorted by NC score

YAP1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	96	Target Neighborhood Hits	96	Shared Neighborhood Hits	96
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

YAP1_HUMAN
NC score	0.936833 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	96	Target Neighborhood Hits	173	Shared Neighborhood Hits	72
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

WWTR1_MOUSE
NC score	0.904695 (rank : 3)	θ value	4.68348e-65 (rank : 4)
Query Neighborhood Hits	96	Target Neighborhood Hits	54	Shared Neighborhood Hits	41
SwissProt Accessions	Q9EPK5, Q99KI4	Gene names	Wwtr1, Taz
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

WWTR1_HUMAN
NC score	0.903264 (rank : 4)	θ value	2.24094e-75 (rank : 3)
Query Neighborhood Hits	96	Target Neighborhood Hits	76	Shared Neighborhood Hits	45
SwissProt Accessions	Q9GZV5, Q8N3P2, Q9Y3W6	Gene names	WWTR1, TAZ
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

SAV1_HUMAN
NC score	0.605154 (rank : 5)	θ value	8.97725e-08 (rank : 26)
Query Neighborhood Hits	96	Target Neighborhood Hits	51	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H4B6, Q6IA58, Q9H949, Q9HAK9	Gene names	SAV1, WW45
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (hWW45).

SAV1_MOUSE
NC score	0.603615 (rank : 6)	θ value	1.53129e-07 (rank : 27)
Query Neighborhood Hits	96	Target Neighborhood Hits	48	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VEB2, Q9D9N9, Q9ER46	Gene names	Sav1, Ww45, Wwp3
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (mWW45).

WWP1_MOUSE
NC score	0.563416 (rank : 7)	θ value	2.60593e-15 (rank : 8)
Query Neighborhood Hits	96	Target Neighborhood Hits	138	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

WWP2_MOUSE
NC score	0.557338 (rank : 8)	θ value	1.86753e-13 (rank : 14)
Query Neighborhood Hits	96	Target Neighborhood Hits	118	Shared Neighborhood Hits	54
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

WWP2_HUMAN
NC score	0.556640 (rank : 9)	θ value	1.86753e-13 (rank : 13)
Query Neighborhood Hits	96	Target Neighborhood Hits	177	Shared Neighborhood Hits	56
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

WWP1_HUMAN
NC score	0.553415 (rank : 10)	θ value	8.38298e-14 (rank : 12)
Query Neighborhood Hits	96	Target Neighborhood Hits	262	Shared Neighborhood Hits	55
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

ITCH_MOUSE
NC score	0.550944 (rank : 11)	θ value	8.38298e-14 (rank : 11)
Query Neighborhood Hits	96	Target Neighborhood Hits	127	Shared Neighborhood Hits	49
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

ITCH_HUMAN
NC score	0.548078 (rank : 12)	θ value	2.20605e-14 (rank : 10)
Query Neighborhood Hits	96	Target Neighborhood Hits	162	Shared Neighborhood Hits	50
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

WWC1_HUMAN
NC score	0.538692 (rank : 13)	θ value	6.00763e-12 (rank : 20)
Query Neighborhood Hits	96	Target Neighborhood Hits	290	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

WWC1_MOUSE
NC score	0.534592 (rank : 14)	θ value	6.00763e-12 (rank : 21)
Query Neighborhood Hits	96	Target Neighborhood Hits	290	Shared Neighborhood Hits	39
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

SMUF2_HUMAN
NC score	0.529131 (rank : 15)	θ value	2.0648e-12 (rank : 17)
Query Neighborhood Hits	96	Target Neighborhood Hits	142	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

SMUF1_MOUSE
NC score	0.521582 (rank : 16)	θ value	3.52202e-12 (rank : 18)
Query Neighborhood Hits	96	Target Neighborhood Hits	142	Shared Neighborhood Hits	40
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

NEDD4_HUMAN
NC score	0.520319 (rank : 17)	θ value	8.10077e-17 (rank : 5)
Query Neighborhood Hits	96	Target Neighborhood Hits	214	Shared Neighborhood Hits	51
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

NED4L_MOUSE
NC score	0.516571 (rank : 18)	θ value	1.80466e-16 (rank : 6)
Query Neighborhood Hits	96	Target Neighborhood Hits	231	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NEDD4_MOUSE
NC score	0.516083 (rank : 19)	θ value	1.68911e-14 (rank : 9)
Query Neighborhood Hits	96	Target Neighborhood Hits	212	Shared Neighborhood Hits	55
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

NED4L_HUMAN
NC score	0.515067 (rank : 20)	θ value	4.02038e-16 (rank : 7)
Query Neighborhood Hits	96	Target Neighborhood Hits	238	Shared Neighborhood Hits	55
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

SMUF1_HUMAN
NC score	0.514704 (rank : 21)	θ value	9.26847e-13 (rank : 15)
Query Neighborhood Hits	96	Target Neighborhood Hits	135	Shared Neighborhood Hits	39
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

WWOX_HUMAN
NC score	0.458815 (rank : 22)	θ value	1.74796e-11 (rank : 22)
Query Neighborhood Hits	96	Target Neighborhood Hits	115	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NZC7, Q5MYT5, Q96KM3, Q96RF2, Q9BTT8, Q9NPC9, Q9NRF4, Q9NRF5, Q9NRF6, Q9NRK1, Q9NZC5	Gene names	WWOX, FOR, WOX1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase).

WWOX_MOUSE
NC score	0.454873 (rank : 23)	θ value	1.74796e-11 (rank : 23)
Query Neighborhood Hits	96	Target Neighborhood Hits	118	Shared Neighborhood Hits	48
SwissProt Accessions	Q91WL8, Q8C8J6, Q920Y2, Q9D2B3, Q9D339, Q9JLF5	Gene names	Wwox, Wox1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-).

BAG3_HUMAN
NC score	0.433871 (rank : 24)	θ value	3.19293e-05 (rank : 30)
Query Neighborhood Hits	96	Target Neighborhood Hits	314	Shared Neighborhood Hits	47
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

MAGI2_MOUSE
NC score	0.425078 (rank : 25)	θ value	8.67504e-11 (rank : 24)
Query Neighborhood Hits	96	Target Neighborhood Hits	370	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

MAGI2_HUMAN
NC score	0.415240 (rank : 26)	θ value	1.47974e-10 (rank : 25)
Query Neighborhood Hits	96	Target Neighborhood Hits	373	Shared Neighborhood Hits	50
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MAGI1_HUMAN
NC score	0.402540 (rank : 27)	θ value	4.59992e-12 (rank : 19)
Query Neighborhood Hits	96	Target Neighborhood Hits	388	Shared Neighborhood Hits	52
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

MAGI1_MOUSE
NC score	0.401988 (rank : 28)	θ value	2.0648e-12 (rank : 16)
Query Neighborhood Hits	96	Target Neighborhood Hits	403	Shared Neighborhood Hits	52
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

PINL_HUMAN
NC score	0.393602 (rank : 29)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	96	Target Neighborhood Hits	47	Shared Neighborhood Hits	40
SwissProt Accessions	O15428	Gene names	PIN1L
Domain Architecture
Description	PIN1-like protein.

BAG3_MOUSE
NC score	0.388871 (rank : 30)	θ value	1.43324e-05 (rank : 28)
Query Neighborhood Hits	96	Target Neighborhood Hits	513	Shared Neighborhood Hits	56
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

PIN1_MOUSE
NC score	0.372003 (rank : 31)	θ value	0.0961366 (rank : 45)
Query Neighborhood Hits	96	Target Neighborhood Hits	60	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QUR7, Q543B3	Gene names	Pin1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

PIN1_HUMAN
NC score	0.361263 (rank : 32)	θ value	0.365318 (rank : 51)
Query Neighborhood Hits	96	Target Neighborhood Hits	59	Shared Neighborhood Hits	39
SwissProt Accessions	Q13526	Gene names	PIN1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

K0317_HUMAN
NC score	0.321087 (rank : 33)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	96	Target Neighborhood Hits	46	Shared Neighborhood Hits	13
SwissProt Accessions	O15033, Q7LDY1, Q8IYY9	Gene names	KIAA0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

K0317_MOUSE
NC score	0.320982 (rank : 34)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	96	Target Neighborhood Hits	43	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CHG5, Q6P9Q1, Q80YC4, Q8C5W5	Gene names	Kiaa0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

PKHA5_HUMAN
NC score	0.315430 (rank : 35)	θ value	1.43324e-05 (rank : 29)
Query Neighborhood Hits	96	Target Neighborhood Hits	455	Shared Neighborhood Hits	40
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

HUWE1_MOUSE
NC score	0.313470 (rank : 36)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	96	Target Neighborhood Hits	406	Shared Neighborhood Hits	25
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

HUWE1_HUMAN
NC score	0.313070 (rank : 37)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	96	Target Neighborhood Hits	443	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HECD2_MOUSE
NC score	0.305534 (rank : 38)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	96	Target Neighborhood Hits	38	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CDU6, Q8CBQ9	Gene names	Hectd2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

HECD2_HUMAN
NC score	0.303897 (rank : 39)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	96	Target Neighborhood Hits	41	Shared Neighborhood Hits	13
SwissProt Accessions	Q5U5R9, Q5VZ97, Q5VZ99, Q8TCP5	Gene names	HECTD2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

UBE3A_HUMAN
NC score	0.296582 (rank : 40)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	96	Target Neighborhood Hits	49	Shared Neighborhood Hits	13
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

UBE3C_HUMAN
NC score	0.293542 (rank : 41)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	96	Target Neighborhood Hits	51	Shared Neighborhood Hits	13
SwissProt Accessions	Q15386, Q8TC15, Q96CR4, Q9UDU3	Gene names	UBE3C, KIAA0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

UBE3A_MOUSE
NC score	0.292702 (rank : 42)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	96	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	O08759, P97482	Gene names	Ube3a
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic protein- associated protein E6-AP).

UBE3C_MOUSE
NC score	0.292528 (rank : 43)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	96	Target Neighborhood Hits	48	Shared Neighborhood Hits	13
SwissProt Accessions	Q80U95, Q8BQZ6, Q8C7W6, Q8CDJ1, Q8VDL5	Gene names	Ube3c, Kiaa0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

TRIPC_HUMAN
NC score	0.276194 (rank : 44)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	96	Target Neighborhood Hits	319	Shared Neighborhood Hits	25
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

STXB4_MOUSE
NC score	0.272693 (rank : 45)	θ value	5.44631e-05 (rank : 31)
Query Neighborhood Hits	96	Target Neighborhood Hits	629	Shared Neighborhood Hits	50
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

GAS7_MOUSE
NC score	0.270360 (rank : 46)	θ value	0.0563607 (rank : 38)
Query Neighborhood Hits	96	Target Neighborhood Hits	259	Shared Neighborhood Hits	44
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

STXB4_HUMAN
NC score	0.268794 (rank : 47)	θ value	0.000158464 (rank : 32)
Query Neighborhood Hits	96	Target Neighborhood Hits	616	Shared Neighborhood Hits	50
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

GAS7_HUMAN
NC score	0.263430 (rank : 48)	θ value	0.163984 (rank : 47)
Query Neighborhood Hits	96	Target Neighborhood Hits	258	Shared Neighborhood Hits	44
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

HERC5_HUMAN
NC score	0.255335 (rank : 49)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	96	Target Neighborhood Hits	66	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UII4	Gene names	HERC5, CEB1, CEBP1
Domain Architecture
Description	HECT domain and RCC1-like domain-containing protein 5 (Cyclin-E- binding protein 1).

HERC3_HUMAN
NC score	0.247833 (rank : 50)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	96	Target Neighborhood Hits	62	Shared Neighborhood Hits	13
SwissProt Accessions	Q15034	Gene names	HERC3, KIAA0032
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain protein 3.

HECD3_MOUSE
NC score	0.214062 (rank : 51)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	96	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q3U487, Q3TN76, Q641P3, Q8BQ74, Q8R1L6	Gene names	Hectd3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

EDD1_MOUSE
NC score	0.213360 (rank : 52)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	96	Target Neighborhood Hits	167	Shared Neighborhood Hits	15
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

EDD1_HUMAN
NC score	0.213132 (rank : 53)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	96	Target Neighborhood Hits	170	Shared Neighborhood Hits	15
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

HECD3_HUMAN
NC score	0.210317 (rank : 54)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	96	Target Neighborhood Hits	49	Shared Neighborhood Hits	13
SwissProt Accessions	Q5T447, Q5T448, Q9H783	Gene names	HECTD3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HERC2_MOUSE
NC score	0.201905 (rank : 55)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	96	Target Neighborhood Hits	167	Shared Neighborhood Hits	17
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

PRP40_HUMAN
NC score	0.200862 (rank : 56)	θ value	0.0736092 (rank : 42)
Query Neighborhood Hits	96	Target Neighborhood Hits	442	Shared Neighborhood Hits	43
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

HERC2_HUMAN
NC score	0.199636 (rank : 57)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	96	Target Neighborhood Hits	163	Shared Neighborhood Hits	17
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

PRP40_MOUSE
NC score	0.194877 (rank : 58)	θ value	0.0736092 (rank : 43)
Query Neighborhood Hits	96	Target Neighborhood Hits	447	Shared Neighborhood Hits	41
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

HECD1_HUMAN
NC score	0.191257 (rank : 59)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	96	Target Neighborhood Hits	371	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

DRP2_HUMAN
NC score	0.149703 (rank : 60)	θ value	0.00869519 (rank : 33)
Query Neighborhood Hits	96	Target Neighborhood Hits	186	Shared Neighborhood Hits	24
SwissProt Accessions	Q13474	Gene names	DRP2
Domain Architecture
Description	Dystrophin-related protein 2.

SETD2_HUMAN
NC score	0.132298 (rank : 61)	θ value	0.62314 (rank : 52)
Query Neighborhood Hits	96	Target Neighborhood Hits	412	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

RHG12_MOUSE
NC score	0.131030 (rank : 62)	θ value	0.00869519 (rank : 34)
Query Neighborhood Hits	96	Target Neighborhood Hits	204	Shared Neighborhood Hits	34
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_HUMAN
NC score	0.115527 (rank : 63)	θ value	0.0148317 (rank : 35)
Query Neighborhood Hits	96	Target Neighborhood Hits	190	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

WBP4_MOUSE
NC score	0.112659 (rank : 64)	θ value	1.81305 (rank : 60)
Query Neighborhood Hits	96	Target Neighborhood Hits	100	Shared Neighborhood Hits	30
SwissProt Accessions	Q61048, Q8K1Z9, Q9CS45	Gene names	Wbp4, Fbp21, Fnbp21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

APBB2_HUMAN
NC score	0.108200 (rank : 65)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	96	Target Neighborhood Hits	96	Shared Neighborhood Hits	27
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

TCRG1_HUMAN
NC score	0.103637 (rank : 66)	θ value	0.0563607 (rank : 39)
Query Neighborhood Hits	96	Target Neighborhood Hits	929	Shared Neighborhood Hits	49
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
NC score	0.102268 (rank : 67)	θ value	0.125558 (rank : 46)
Query Neighborhood Hits	96	Target Neighborhood Hits	947	Shared Neighborhood Hits	50
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

WWC3_HUMAN
NC score	0.101402 (rank : 68)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	96	Target Neighborhood Hits	193	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ULE0, Q659C1, Q9BTQ1	Gene names	WWC3, KIAA1280
Domain Architecture	No domain graphic available
Description	WWC family member 3.

APBB2_MOUSE
NC score	0.095418 (rank : 69)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	96	Target Neighborhood Hits	88	Shared Neighborhood Hits	24
SwissProt Accessions	Q9DBR4, Q6DFX8	Gene names	Apbb2
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2.

DGCR8_HUMAN
NC score	0.093202 (rank : 70)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	96	Target Neighborhood Hits	72	Shared Neighborhood Hits	16
SwissProt Accessions	Q8WYQ5, Q6DCB2, Q6MZE9, Q6Y2L0, Q96G39, Q96GP8, Q9H6L8, Q9H6T7, Q9NRW2	Gene names	DGCR8, C22orf12, DGCRK6
Domain Architecture
Description	DGCR8 protein (DiGeorge syndrome critical region 8).

DGCR8_MOUSE
NC score	0.090064 (rank : 71)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	96	Target Neighborhood Hits	70	Shared Neighborhood Hits	14
SwissProt Accessions	Q9EQM6	Gene names	Dgcr8
Domain Architecture	No domain graphic available
Description	DGCR8 protein (DiGeorge syndrome critical region 8 homolog) (Gy1).

APBB1_MOUSE
NC score	0.085122 (rank : 72)	θ value	0.365318 (rank : 50)
Query Neighborhood Hits	96	Target Neighborhood Hits	75	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QXJ1, O08642, Q3TPU0, Q8BNF4, Q8BSR9	Gene names	Apbb1, Fe65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

APBB1_HUMAN
NC score	0.084609 (rank : 73)	θ value	0.365318 (rank : 49)
Query Neighborhood Hits	96	Target Neighborhood Hits	62	Shared Neighborhood Hits	19
SwissProt Accessions	O00213, Q96A93	Gene names	APBB1, FE65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

APBB3_HUMAN
NC score	0.082548 (rank : 74)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	96	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	O95704, Q9NYX6, Q9NYX7, Q9NYX8	Gene names	APBB3, FE65L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 3 (Fe65-like protein 2) (Fe65L2).

APBB3_MOUSE
NC score	0.080661 (rank : 75)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	96	Target Neighborhood Hits	32	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R1C9	Gene names	Apbb3
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 3.

DMD_HUMAN
NC score	0.077393 (rank : 76)	θ value	0.0193708 (rank : 36)
Query Neighborhood Hits	96	Target Neighborhood Hits	1135	Shared Neighborhood Hits	39
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

PCLO_MOUSE
NC score	0.075826 (rank : 77)	θ value	0.21417 (rank : 48)
Query Neighborhood Hits	96	Target Neighborhood Hits	2275	Shared Neighborhood Hits	59
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

DMD_MOUSE
NC score	0.073611 (rank : 78)	θ value	0.0193708 (rank : 37)
Query Neighborhood Hits	96	Target Neighborhood Hits	1111	Shared Neighborhood Hits	39
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

UTRO_HUMAN
NC score	0.069585 (rank : 79)	θ value	0.0736092 (rank : 44)
Query Neighborhood Hits	96	Target Neighborhood Hits	960	Shared Neighborhood Hits	39
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

FA62A_MOUSE
NC score	0.063919 (rank : 80)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	96	Target Neighborhood Hits	155	Shared Neighborhood Hits	12
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

K1849_HUMAN
NC score	0.061092 (rank : 81)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	96	Target Neighborhood Hits	220	Shared Neighborhood Hits	14
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

WHRN_MOUSE
NC score	0.060280 (rank : 82)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	96	Target Neighborhood Hits	412	Shared Neighborhood Hits	22
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

UN13B_MOUSE
NC score	0.059510 (rank : 83)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	96	Target Neighborhood Hits	210	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13B_HUMAN
NC score	0.059345 (rank : 84)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	96	Target Neighborhood Hits	217	Shared Neighborhood Hits	10
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

PARD3_MOUSE
NC score	0.057142 (rank : 85)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	96	Target Neighborhood Hits	290	Shared Neighborhood Hits	12
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

UN13A_HUMAN
NC score	0.056995 (rank : 86)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	96	Target Neighborhood Hits	285	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

PCLO_HUMAN
NC score	0.055992 (rank : 87)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	96	Target Neighborhood Hits	2046	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RIMS2_MOUSE
NC score	0.055814 (rank : 88)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	96	Target Neighborhood Hits	376	Shared Neighborhood Hits	25
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

RIMS2_HUMAN
NC score	0.055267 (rank : 89)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	96	Target Neighborhood Hits	342	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

DHRSX_HUMAN
NC score	0.054792 (rank : 90)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	96	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N5I4, Q6UWC7, Q8WUS4, Q96GR8, Q9NTF6	Gene names	DHRSX, CXorf11, DHRS5X
Domain Architecture
Description	Dehydrogenase/reductase SDR family member on chromosome X precursor (EC 1.1.-.-) (DHRSXY).

PARD3_HUMAN
NC score	0.054497 (rank : 91)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	96	Target Neighborhood Hits	312	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

FA62A_HUMAN
NC score	0.054421 (rank : 92)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	96	Target Neighborhood Hits	168	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

K1849_MOUSE
NC score	0.054384 (rank : 93)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	96	Target Neighborhood Hits	335	Shared Neighborhood Hits	12
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

MPDZ_HUMAN
NC score	0.054373 (rank : 94)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	96	Target Neighborhood Hits	261	Shared Neighborhood Hits	10
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

SYJ2B_HUMAN
NC score	0.054223 (rank : 95)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	96	Target Neighborhood Hits	162	Shared Neighborhood Hits	9
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

WBP4_HUMAN
NC score	0.053303 (rank : 96)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	96	Target Neighborhood Hits	86	Shared Neighborhood Hits	20
SwissProt Accessions	O75554	Gene names	WBP4, FBP21, FNBP21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

RDH14_HUMAN
NC score	0.052814 (rank : 97)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	96	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HBH5	Gene names	RDH14, PAN2
Domain Architecture
Description	Retinol dehydrogenase 14 (EC 1.1.1.-) (Alcohol dehydrogenase PAN2).

RDH12_MOUSE
NC score	0.052684 (rank : 98)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	96	Target Neighborhood Hits	74	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BYK4, Q91WA5, Q9D1Y4	Gene names	Rdh12
Domain Architecture
Description	Retinol dehydrogenase 12 (EC 1.1.1.-).

RASL1_HUMAN
NC score	0.052508 (rank : 99)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	96	Target Neighborhood Hits	142	Shared Neighborhood Hits	8
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

DOC2B_HUMAN
NC score	0.052335 (rank : 100)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	96	Target Neighborhood Hits	150	Shared Neighborhood Hits	12
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

RDH14_MOUSE
NC score	0.052212 (rank : 101)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	96	Target Neighborhood Hits	74	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ERI6	Gene names	Rdh14
Domain Architecture
Description	Retinol dehydrogenase 14 (EC 1.1.1.-) (Alcohol dehydrogenase PAN2).

LIN7C_HUMAN
NC score	0.052043 (rank : 102)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	96	Target Neighborhood Hits	198	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
NC score	0.052043 (rank : 103)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	96	Target Neighborhood Hits	198	Shared Neighborhood Hits	9
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

DOC2B_MOUSE
NC score	0.051534 (rank : 104)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	96	Target Neighborhood Hits	169	Shared Neighborhood Hits	13
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

DOC2A_MOUSE
NC score	0.051477 (rank : 105)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	96	Target Neighborhood Hits	140	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

LIN7B_MOUSE
NC score	0.051467 (rank : 106)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	96	Target Neighborhood Hits	200	Shared Neighborhood Hits	9
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

MPDZ_MOUSE
NC score	0.051199 (rank : 107)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	96	Target Neighborhood Hits	298	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

RDH12_HUMAN
NC score	0.051039 (rank : 108)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	96	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q96NR8, Q8TAW6	Gene names	RDH12
Domain Architecture
Description	Retinol dehydrogenase 12 (EC 1.1.1.-) (All-trans and 9-cis retinol dehydrogenase).

INADL_MOUSE
NC score	0.050912 (rank : 109)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	96	Target Neighborhood Hits	290	Shared Neighborhood Hits	12
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

LIN7B_HUMAN
NC score	0.050677 (rank : 110)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	96	Target Neighborhood Hits	200	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

PAR3L_HUMAN
NC score	0.050204 (rank : 111)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	96	Target Neighborhood Hits	297	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

CN152_HUMAN
NC score	0.049322 (rank : 112)	θ value	2.36792 (rank : 61)
Query Neighborhood Hits	96	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N9Y4, Q96GY1	Gene names	C14orf152
Domain Architecture	No domain graphic available
Description	Protein C14orf152.

MDC1_HUMAN
NC score	0.040234 (rank : 113)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	96	Target Neighborhood Hits	1446	Shared Neighborhood Hits	35
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

OGFR_HUMAN
NC score	0.039371 (rank : 114)	θ value	0.0736092 (rank : 41)
Query Neighborhood Hits	96	Target Neighborhood Hits	1582	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

NEB2_MOUSE
NC score	0.039278 (rank : 115)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	96	Target Neighborhood Hits	889	Shared Neighborhood Hits	24
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

ANC1_MOUSE
NC score	0.037165 (rank : 116)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	96	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	P53995, Q8BP33, Q8C772	Gene names	Anapc1, Mcpr, Tsg24
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Protein Tsg24) (Mitotic checkpoint regulator).

GRIN1_MOUSE
NC score	0.036598 (rank : 117)	θ value	2.36792 (rank : 62)
Query Neighborhood Hits	96	Target Neighborhood Hits	337	Shared Neighborhood Hits	18
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

ANC1_HUMAN
NC score	0.033980 (rank : 118)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	96	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H1A4, Q9BSE6, Q9H8D0	Gene names	ANAPC1, TSG24
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Protein Tsg24) (Mitotic checkpoint regulator).

RGS3_MOUSE
NC score	0.032836 (rank : 119)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	96	Target Neighborhood Hits	1621	Shared Neighborhood Hits	39
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

PI5PA_HUMAN
NC score	0.031466 (rank : 120)	θ value	2.36792 (rank : 65)
Query Neighborhood Hits	96	Target Neighborhood Hits	749	Shared Neighborhood Hits	24
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

OGFR_MOUSE
NC score	0.030354 (rank : 121)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	96	Target Neighborhood Hits	584	Shared Neighborhood Hits	15
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

BSN_HUMAN
NC score	0.030240 (rank : 122)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	96	Target Neighborhood Hits	1537	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

BAT2_HUMAN
NC score	0.028617 (rank : 123)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	96	Target Neighborhood Hits	931	Shared Neighborhood Hits	30
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

NCOA6_MOUSE
NC score	0.027937 (rank : 124)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	96	Target Neighborhood Hits	1076	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

BAZ2A_MOUSE
NC score	0.025623 (rank : 125)	θ value	0.813845 (rank : 54)
Query Neighborhood Hits	96	Target Neighborhood Hits	744	Shared Neighborhood Hits	23
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

MUC1_HUMAN
NC score	0.023266 (rank : 126)	θ value	1.06291 (rank : 57)
Query Neighborhood Hits	96	Target Neighborhood Hits	975	Shared Neighborhood Hits	27
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

FILA_HUMAN
NC score	0.022967 (rank : 127)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	96	Target Neighborhood Hits	685	Shared Neighborhood Hits	19
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

TRAIP_HUMAN
NC score	0.021771 (rank : 128)	θ value	0.62314 (rank : 53)
Query Neighborhood Hits	96	Target Neighborhood Hits	780	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

K1543_HUMAN
NC score	0.021366 (rank : 129)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	96	Target Neighborhood Hits	435	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

NFH_MOUSE
NC score	0.021149 (rank : 130)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	96	Target Neighborhood Hits	2247	Shared Neighborhood Hits	43
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

ZEP2_HUMAN
NC score	0.019384 (rank : 131)	θ value	0.0563607 (rank : 40)
Query Neighborhood Hits	96	Target Neighborhood Hits	937	Shared Neighborhood Hits	11
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

CEL_HUMAN
NC score	0.018661 (rank : 132)	θ value	1.38821 (rank : 58)
Query Neighborhood Hits	96	Target Neighborhood Hits	896	Shared Neighborhood Hits	21
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

DYDC1_HUMAN
NC score	0.018533 (rank : 133)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	96	Target Neighborhood Hits	142	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WWB3, Q5QP03, Q5QP04, Q6WNP4, Q6ZU87	Gene names	DYDC1, DPY30D1
Domain Architecture	No domain graphic available
Description	DPY30 domain-containing protein 1 (RSD-9).

ANK2_HUMAN
NC score	0.018210 (rank : 134)	θ value	1.81305 (rank : 59)
Query Neighborhood Hits	96	Target Neighborhood Hits	1615	Shared Neighborhood Hits	42
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

GPTC8_HUMAN
NC score	0.016657 (rank : 135)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	96	Target Neighborhood Hits	366	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

PAX1_MOUSE
NC score	0.015217 (rank : 136)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	96	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	P09084, Q9R2B1	Gene names	Pax1, Pax-1
Domain Architecture
Description	Paired box protein Pax-1.

CDC37_HUMAN
NC score	0.013976 (rank : 137)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	96	Target Neighborhood Hits	506	Shared Neighborhood Hits	11
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

ZEP1_MOUSE
NC score	0.013306 (rank : 138)	θ value	0.813845 (rank : 56)
Query Neighborhood Hits	96	Target Neighborhood Hits	1063	Shared Neighborhood Hits	20
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

PIAS4_MOUSE
NC score	0.012047 (rank : 139)	θ value	2.36792 (rank : 66)
Query Neighborhood Hits	96	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JM05, Q8R165	Gene names	Pias4, Piasg
Domain Architecture
Description	Protein inhibitor of activated STAT protein 4 (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma) (PIASy).

T240L_MOUSE
NC score	0.011753 (rank : 140)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	96	Target Neighborhood Hits	143	Shared Neighborhood Hits	10
SwissProt Accessions	Q6JPI3, Q3TRF4, Q3UQI8, Q80TM3, Q80WQ0	Gene names	Thrap2, Kiaa1025, Trap240l
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

MAD3_HUMAN
NC score	0.011746 (rank : 141)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	96	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3	Gene names	MXD3, MAD3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).

TTBK1_HUMAN
NC score	0.010200 (rank : 142)	θ value	0.813845 (rank : 55)
Query Neighborhood Hits	96	Target Neighborhood Hits	1058	Shared Neighborhood Hits	16
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

KIF5C_HUMAN
NC score	0.009946 (rank : 143)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	96	Target Neighborhood Hits	974	Shared Neighborhood Hits	18
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

SMAD4_MOUSE
NC score	0.009919 (rank : 144)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	96	Target Neighborhood Hits	101	Shared Neighborhood Hits	4
SwissProt Accessions	P97471, Q9CW56	Gene names	Smad4, Dpc4, Madh4
Domain Architecture
Description	Mothers against decapentaplegic homolog 4 (SMAD 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4 homolog) (Smad4).

KIF5C_MOUSE
NC score	0.009231 (rank : 145)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	96	Target Neighborhood Hits	1040	Shared Neighborhood Hits	18
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

CP135_HUMAN
NC score	0.009213 (rank : 146)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	96	Target Neighborhood Hits	1290	Shared Neighborhood Hits	26
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

PER2_MOUSE
NC score	0.006641 (rank : 147)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	96	Target Neighborhood Hits	325	Shared Neighborhood Hits	8
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

RBM11_HUMAN
NC score	0.005762 (rank : 148)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	96	Target Neighborhood Hits	149	Shared Neighborhood Hits	2
SwissProt Accessions	P57052	Gene names	RBM11
Domain Architecture
Description	Putative RNA-binding protein 11 (RNA-binding motif protein 11).

CAC1G_HUMAN
NC score	0.004020 (rank : 149)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	96	Target Neighborhood Hits	587	Shared Neighborhood Hits	14
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

NOTC2_HUMAN
NC score	0.002985 (rank : 150)	θ value	2.36792 (rank : 63)
Query Neighborhood Hits	96	Target Neighborhood Hits	1113	Shared Neighborhood Hits	13
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

CD2L7_HUMAN
NC score	-0.000337 (rank : 151)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	96	Target Neighborhood Hits	1275	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

ZN232_HUMAN
NC score	-0.003568 (rank : 152)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	96	Target Neighborhood Hits	754	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UNY5	Gene names	ZNF232, ZSCAN11
Domain Architecture
Description	Zinc finger protein 232 (Zinc finger and SCAN domain-containing protein 11).