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Network neighborhood for query Sequence : CAC1G_HUMAN

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CAC1G_HUMAN
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CAC1G_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	587	Target Neighborhood Hits	587	Shared Neighborhood Hits	587
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CAC1H_HUMAN
θ value	0 (rank : 2)	NC score	0.951156 (rank : 4)
Query Neighborhood Hits	587	Target Neighborhood Hits	307	Shared Neighborhood Hits	127
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CAC1H_MOUSE
θ value	0 (rank : 3)	NC score	0.955236 (rank : 2)
Query Neighborhood Hits	587	Target Neighborhood Hits	230	Shared Neighborhood Hits	105
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CAC1I_HUMAN
θ value	0 (rank : 4)	NC score	0.951967 (rank : 3)
Query Neighborhood Hits	587	Target Neighborhood Hits	138	Shared Neighborhood Hits	78
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

SC11A_HUMAN
θ value	7.19216e-82 (rank : 5)	NC score	0.866908 (rank : 5)
Query Neighborhood Hits	587	Target Neighborhood Hits	111	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

SC11A_MOUSE
θ value	2.92676e-75 (rank : 6)	NC score	0.866486 (rank : 6)
Query Neighborhood Hits	587	Target Neighborhood Hits	116	Shared Neighborhood Hits	67
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

SCN4A_HUMAN
θ value	2.09745e-73 (rank : 7)	NC score	0.859332 (rank : 10)
Query Neighborhood Hits	587	Target Neighborhood Hits	133	Shared Neighborhood Hits	66
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

SCN2A_HUMAN
θ value	9.74306e-71 (rank : 8)	NC score	0.850154 (rank : 23)
Query Neighborhood Hits	587	Target Neighborhood Hits	157	Shared Neighborhood Hits	62
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SCN3A_HUMAN
θ value	1.27248e-70 (rank : 9)	NC score	0.853204 (rank : 18)
Query Neighborhood Hits	587	Target Neighborhood Hits	115	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

CAC1S_MOUSE
θ value	2.17053e-70 (rank : 10)	NC score	0.858005 (rank : 14)
Query Neighborhood Hits	587	Target Neighborhood Hits	98	Shared Neighborhood Hits	66
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

SCN1A_HUMAN
θ value	3.70236e-70 (rank : 11)	NC score	0.849262 (rank : 24)
Query Neighborhood Hits	587	Target Neighborhood Hits	148	Shared Neighborhood Hits	59
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

CAC1D_HUMAN
θ value	4.83544e-70 (rank : 12)	NC score	0.856943 (rank : 15)
Query Neighborhood Hits	587	Target Neighborhood Hits	118	Shared Neighborhood Hits	65
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CAC1E_HUMAN
θ value	6.98233e-69 (rank : 13)	NC score	0.863269 (rank : 8)
Query Neighborhood Hits	587	Target Neighborhood Hits	148	Shared Neighborhood Hits	66
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_MOUSE
θ value	9.11921e-69 (rank : 14)	NC score	0.863495 (rank : 7)
Query Neighborhood Hits	587	Target Neighborhood Hits	167	Shared Neighborhood Hits	68
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

SCN9A_HUMAN
θ value	1.00825e-67 (rank : 15)	NC score	0.848899 (rank : 25)
Query Neighborhood Hits	587	Target Neighborhood Hits	157	Shared Neighborhood Hits	61
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

CAC1S_HUMAN
θ value	1.31681e-67 (rank : 16)	NC score	0.856547 (rank : 16)
Query Neighborhood Hits	587	Target Neighborhood Hits	92	Shared Neighborhood Hits	61
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1B_MOUSE
θ value	2.93355e-67 (rank : 17)	NC score	0.858435 (rank : 12)
Query Neighborhood Hits	587	Target Neighborhood Hits	351	Shared Neighborhood Hits	139
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1A_HUMAN
θ value	9.43692e-66 (rank : 18)	NC score	0.859398 (rank : 9)
Query Neighborhood Hits	587	Target Neighborhood Hits	387	Shared Neighborhood Hits	150
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1A_MOUSE
θ value	2.74572e-65 (rank : 19)	NC score	0.858457 (rank : 11)
Query Neighborhood Hits	587	Target Neighborhood Hits	267	Shared Neighborhood Hits	102
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1C_MOUSE
θ value	2.32439e-64 (rank : 20)	NC score	0.850315 (rank : 22)
Query Neighborhood Hits	587	Target Neighborhood Hits	130	Shared Neighborhood Hits	60
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CAC1F_HUMAN
θ value	1.15359e-63 (rank : 21)	NC score	0.852978 (rank : 19)
Query Neighborhood Hits	587	Target Neighborhood Hits	141	Shared Neighborhood Hits	70
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

SCN5A_HUMAN
θ value	1.96772e-63 (rank : 22)	NC score	0.858302 (rank : 13)
Query Neighborhood Hits	587	Target Neighborhood Hits	145	Shared Neighborhood Hits	69
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

CAC1F_MOUSE
θ value	9.76566e-63 (rank : 23)	NC score	0.852116 (rank : 21)
Query Neighborhood Hits	587	Target Neighborhood Hits	142	Shared Neighborhood Hits	68
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1B_HUMAN
θ value	3.71096e-62 (rank : 24)	NC score	0.856329 (rank : 17)
Query Neighborhood Hits	587	Target Neighborhood Hits	257	Shared Neighborhood Hits	90
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

SC10A_MOUSE
θ value	6.32992e-62 (rank : 25)	NC score	0.848264 (rank : 26)
Query Neighborhood Hits	587	Target Neighborhood Hits	107	Shared Neighborhood Hits	61
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

SC10A_HUMAN
θ value	4.10295e-61 (rank : 26)	NC score	0.847021 (rank : 28)
Query Neighborhood Hits	587	Target Neighborhood Hits	116	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

SCN8A_MOUSE
θ value	4.53632e-60 (rank : 27)	NC score	0.845347 (rank : 29)
Query Neighborhood Hits	587	Target Neighborhood Hits	136	Shared Neighborhood Hits	63
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN8A_HUMAN
θ value	5.92465e-60 (rank : 28)	NC score	0.847406 (rank : 27)
Query Neighborhood Hits	587	Target Neighborhood Hits	135	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

CAC1C_HUMAN
θ value	4.24587e-58 (rank : 29)	NC score	0.844169 (rank : 30)
Query Neighborhood Hits	587	Target Neighborhood Hits	158	Shared Neighborhood Hits	59
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

SCN7A_HUMAN
θ value	8.00737e-57 (rank : 30)	NC score	0.852488 (rank : 20)
Query Neighborhood Hits	587	Target Neighborhood Hits	135	Shared Neighborhood Hits	55
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

KCNV2_HUMAN
θ value	2.88788e-06 (rank : 31)	NC score	0.239519 (rank : 36)
Query Neighborhood Hits	587	Target Neighborhood Hits	137	Shared Neighborhood Hits	55
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

ATN1_HUMAN
θ value	5.44631e-05 (rank : 32)	NC score	0.090155 (rank : 83)
Query Neighborhood Hits	587	Target Neighborhood Hits	676	Shared Neighborhood Hits	116
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

MLL4_HUMAN
θ value	5.44631e-05 (rank : 33)	NC score	0.065834 (rank : 148)
Query Neighborhood Hits	587	Target Neighborhood Hits	722	Shared Neighborhood Hits	132
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

BSN_MOUSE
θ value	7.1131e-05 (rank : 34)	NC score	0.127345 (rank : 57)
Query Neighborhood Hits	587	Target Neighborhood Hits	2057	Shared Neighborhood Hits	341
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

KCNS2_MOUSE
θ value	9.29e-05 (rank : 35)	NC score	0.220624 (rank : 39)
Query Neighborhood Hits	587	Target Neighborhood Hits	130	Shared Neighborhood Hits	57
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

SFPQ_HUMAN
θ value	0.000121331 (rank : 36)	NC score	0.063221 (rank : 158)
Query Neighborhood Hits	587	Target Neighborhood Hits	986	Shared Neighborhood Hits	126
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

KCNS2_HUMAN
θ value	0.000158464 (rank : 37)	NC score	0.216212 (rank : 40)
Query Neighborhood Hits	587	Target Neighborhood Hits	129	Shared Neighborhood Hits	56
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

BSN_HUMAN
θ value	0.00020696 (rank : 38)	NC score	0.100746 (rank : 70)
Query Neighborhood Hits	587	Target Neighborhood Hits	1537	Shared Neighborhood Hits	238
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

GGN_HUMAN
θ value	0.00020696 (rank : 39)	NC score	0.085457 (rank : 93)
Query Neighborhood Hits	587	Target Neighborhood Hits	269	Shared Neighborhood Hits	67
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

RAPH1_HUMAN
θ value	0.000270298 (rank : 40)	NC score	0.066736 (rank : 144)
Query Neighborhood Hits	587	Target Neighborhood Hits	593	Shared Neighborhood Hits	116
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

ZN219_HUMAN
θ value	0.000270298 (rank : 41)	NC score	0.013038 (rank : 483)
Query Neighborhood Hits	587	Target Neighborhood Hits	876	Shared Neighborhood Hits	68
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

MILK1_MOUSE
θ value	0.00035302 (rank : 42)	NC score	0.077048 (rank : 117)
Query Neighborhood Hits	587	Target Neighborhood Hits	788	Shared Neighborhood Hits	201
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

HCN4_HUMAN
θ value	0.000461057 (rank : 43)	NC score	0.042849 (rank : 242)
Query Neighborhood Hits	587	Target Neighborhood Hits	303	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

IQEC3_MOUSE
θ value	0.000461057 (rank : 44)	NC score	0.054853 (rank : 200)
Query Neighborhood Hits	587	Target Neighborhood Hits	274	Shared Neighborhood Hits	71
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

SRRM1_MOUSE
θ value	0.000461057 (rank : 45)	NC score	0.115433 (rank : 64)
Query Neighborhood Hits	587	Target Neighborhood Hits	966	Shared Neighborhood Hits	208
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

KCNF1_HUMAN
θ value	0.000602161 (rank : 46)	NC score	0.235979 (rank : 37)
Query Neighborhood Hits	587	Target Neighborhood Hits	109	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

BRD4_MOUSE
θ value	0.000786445 (rank : 47)	NC score	0.048533 (rank : 226)
Query Neighborhood Hits	587	Target Neighborhood Hits	845	Shared Neighborhood Hits	109
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

RERE_MOUSE
θ value	0.000786445 (rank : 48)	NC score	0.077897 (rank : 113)
Query Neighborhood Hits	587	Target Neighborhood Hits	785	Shared Neighborhood Hits	126
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

KCNB1_HUMAN
θ value	0.00102713 (rank : 49)	NC score	0.211826 (rank : 41)
Query Neighborhood Hits	587	Target Neighborhood Hits	169	Shared Neighborhood Hits	62
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNB1_MOUSE
θ value	0.00102713 (rank : 50)	NC score	0.211356 (rank : 42)
Query Neighborhood Hits	587	Target Neighborhood Hits	154	Shared Neighborhood Hits	59
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

M3K11_HUMAN
θ value	0.00102713 (rank : 51)	NC score	0.011336 (rank : 511)
Query Neighborhood Hits	587	Target Neighborhood Hits	1136	Shared Neighborhood Hits	75
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

KCNB2_HUMAN
θ value	0.00134147 (rank : 52)	NC score	0.224058 (rank : 38)
Query Neighborhood Hits	587	Target Neighborhood Hits	212	Shared Neighborhood Hits	76
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

K1802_HUMAN
θ value	0.00175202 (rank : 53)	NC score	0.061438 (rank : 165)
Query Neighborhood Hits	587	Target Neighborhood Hits	1378	Shared Neighborhood Hits	212
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MINT_MOUSE
θ value	0.00175202 (rank : 54)	NC score	0.078072 (rank : 112)
Query Neighborhood Hits	587	Target Neighborhood Hits	1514	Shared Neighborhood Hits	242
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SRRM1_HUMAN
θ value	0.00175202 (rank : 55)	NC score	0.084309 (rank : 95)
Query Neighborhood Hits	587	Target Neighborhood Hits	690	Shared Neighborhood Hits	114
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

MILK1_HUMAN
θ value	0.00298849 (rank : 56)	NC score	0.050330 (rank : 219)
Query Neighborhood Hits	587	Target Neighborhood Hits	427	Shared Neighborhood Hits	78
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

KCNS3_HUMAN
θ value	0.00390308 (rank : 57)	NC score	0.188135 (rank : 43)
Query Neighborhood Hits	587	Target Neighborhood Hits	125	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

PCLO_HUMAN
θ value	0.00390308 (rank : 58)	NC score	0.094716 (rank : 77)
Query Neighborhood Hits	587	Target Neighborhood Hits	2046	Shared Neighborhood Hits	285
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

YLPM1_MOUSE
θ value	0.00390308 (rank : 59)	NC score	0.075509 (rank : 120)
Query Neighborhood Hits	587	Target Neighborhood Hits	505	Shared Neighborhood Hits	93
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

SAPS1_HUMAN
θ value	0.00509761 (rank : 60)	NC score	0.090255 (rank : 82)
Query Neighborhood Hits	587	Target Neighborhood Hits	704	Shared Neighborhood Hits	237
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

IRS2_MOUSE
θ value	0.00665767 (rank : 61)	NC score	0.055229 (rank : 196)
Query Neighborhood Hits	587	Target Neighborhood Hits	248	Shared Neighborhood Hits	61
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

SRRM2_MOUSE
θ value	0.00665767 (rank : 62)	NC score	0.096376 (rank : 76)
Query Neighborhood Hits	587	Target Neighborhood Hits	1470	Shared Neighborhood Hits	240
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

MBD6_HUMAN
θ value	0.00869519 (rank : 63)	NC score	0.075016 (rank : 121)
Query Neighborhood Hits	587	Target Neighborhood Hits	349	Shared Neighborhood Hits	88
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

PTN23_HUMAN
θ value	0.00869519 (rank : 64)	NC score	0.030444 (rank : 313)
Query Neighborhood Hits	587	Target Neighborhood Hits	646	Shared Neighborhood Hits	90
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

SRRM2_HUMAN
θ value	0.00869519 (rank : 65)	NC score	0.087412 (rank : 88)
Query Neighborhood Hits	587	Target Neighborhood Hits	1296	Shared Neighborhood Hits	199
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TNC6B_HUMAN
θ value	0.0113563 (rank : 66)	NC score	0.045434 (rank : 234)
Query Neighborhood Hits	587	Target Neighborhood Hits	256	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

BAT2_HUMAN
θ value	0.0148317 (rank : 67)	NC score	0.101272 (rank : 69)
Query Neighborhood Hits	587	Target Neighborhood Hits	931	Shared Neighborhood Hits	214
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

ENAH_MOUSE
θ value	0.0148317 (rank : 68)	NC score	0.059946 (rank : 175)
Query Neighborhood Hits	587	Target Neighborhood Hits	919	Shared Neighborhood Hits	121
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

PRP2_MOUSE
θ value	0.0148317 (rank : 69)	NC score	0.071273 (rank : 131)
Query Neighborhood Hits	587	Target Neighborhood Hits	347	Shared Neighborhood Hits	74
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

SGIP1_MOUSE
θ value	0.0148317 (rank : 70)	NC score	0.067520 (rank : 143)
Query Neighborhood Hits	587	Target Neighborhood Hits	180	Shared Neighborhood Hits	49
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

KCNS1_HUMAN
θ value	0.0193708 (rank : 71)	NC score	0.164256 (rank : 49)
Query Neighborhood Hits	587	Target Neighborhood Hits	116	Shared Neighborhood Hits	55
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

SREC2_HUMAN
θ value	0.0193708 (rank : 72)	NC score	0.020443 (rank : 405)
Query Neighborhood Hits	587	Target Neighborhood Hits	645	Shared Neighborhood Hits	52
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

ZDHC8_MOUSE
θ value	0.0193708 (rank : 73)	NC score	0.035762 (rank : 283)
Query Neighborhood Hits	587	Target Neighborhood Hits	243	Shared Neighborhood Hits	71
SwissProt Accessions	Q5Y5T5, Q7TNF7	Gene names	Zdhhc8
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8).

ACK1_HUMAN
θ value	0.0252991 (rank : 74)	NC score	0.014084 (rank : 467)
Query Neighborhood Hits	587	Target Neighborhood Hits	1140	Shared Neighborhood Hits	125
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

CT151_HUMAN
θ value	0.0252991 (rank : 75)	NC score	0.055397 (rank : 193)
Query Neighborhood Hits	587	Target Neighborhood Hits	382	Shared Neighborhood Hits	68
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

PRP1_HUMAN
θ value	0.0252991 (rank : 76)	NC score	0.083908 (rank : 99)
Query Neighborhood Hits	587	Target Neighborhood Hits	385	Shared Neighborhood Hits	94
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

RP1L1_HUMAN
θ value	0.0252991 (rank : 77)	NC score	0.043784 (rank : 238)
Query Neighborhood Hits	587	Target Neighborhood Hits	1072	Shared Neighborhood Hits	155
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

ACK1_MOUSE
θ value	0.0330416 (rank : 78)	NC score	0.014650 (rank : 459)
Query Neighborhood Hits	587	Target Neighborhood Hits	1080	Shared Neighborhood Hits	107
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

BAT2_MOUSE
θ value	0.0330416 (rank : 79)	NC score	0.099439 (rank : 73)
Query Neighborhood Hits	587	Target Neighborhood Hits	947	Shared Neighborhood Hits	233
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

GSCR1_HUMAN
θ value	0.0330416 (rank : 80)	NC score	0.074391 (rank : 123)
Query Neighborhood Hits	587	Target Neighborhood Hits	674	Shared Neighborhood Hits	140
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

K1949_MOUSE
θ value	0.0330416 (rank : 81)	NC score	0.038437 (rank : 264)
Query Neighborhood Hits	587	Target Neighborhood Hits	134	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BQ30, Q3UDS6, Q8CEY9, Q8R3D8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1949 homolog.

KCND3_HUMAN
θ value	0.0330416 (rank : 82)	NC score	0.176758 (rank : 45)
Query Neighborhood Hits	587	Target Neighborhood Hits	162	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_MOUSE
θ value	0.0330416 (rank : 83)	NC score	0.176913 (rank : 44)
Query Neighborhood Hits	587	Target Neighborhood Hits	162	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCNS1_MOUSE
θ value	0.0330416 (rank : 84)	NC score	0.153028 (rank : 52)
Query Neighborhood Hits	587	Target Neighborhood Hits	114	Shared Neighborhood Hits	49
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

PAK6_HUMAN
θ value	0.0330416 (rank : 85)	NC score	0.003110 (rank : 613)
Query Neighborhood Hits	587	Target Neighborhood Hits	915	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NQU5	Gene names	PAK6, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (p21-activated kinase 6) (PAK-6) (PAK-5).

PLXB1_MOUSE
θ value	0.0330416 (rank : 86)	NC score	0.018588 (rank : 421)
Query Neighborhood Hits	587	Target Neighborhood Hits	259	Shared Neighborhood Hits	66
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

RERE_HUMAN
θ value	0.0330416 (rank : 87)	NC score	0.066379 (rank : 146)
Query Neighborhood Hits	587	Target Neighborhood Hits	779	Shared Neighborhood Hits	129
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

SGIP1_HUMAN
θ value	0.0330416 (rank : 88)	NC score	0.064216 (rank : 153)
Query Neighborhood Hits	587	Target Neighborhood Hits	198	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

HXA3_MOUSE
θ value	0.0431538 (rank : 89)	NC score	0.020466 (rank : 403)
Query Neighborhood Hits	587	Target Neighborhood Hits	558	Shared Neighborhood Hits	72
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

HXC9_HUMAN
θ value	0.0431538 (rank : 90)	NC score	0.015981 (rank : 445)
Query Neighborhood Hits	587	Target Neighborhood Hits	339	Shared Neighborhood Hits	24
SwissProt Accessions	P31274, Q9H1I0	Gene names	HOXC9, HOX3B
Domain Architecture
Description	Homeobox protein Hox-C9 (Hox-3B).

HXC9_MOUSE
θ value	0.0431538 (rank : 91)	NC score	0.015951 (rank : 446)
Query Neighborhood Hits	587	Target Neighborhood Hits	338	Shared Neighborhood Hits	24
SwissProt Accessions	P09633	Gene names	Hoxc9, Hox-3.2, Hoxc-9
Domain Architecture
Description	Homeobox protein Hox-C9 (Hox-3.2).

PHC2_HUMAN
θ value	0.0431538 (rank : 92)	NC score	0.063140 (rank : 159)
Query Neighborhood Hits	587	Target Neighborhood Hits	388	Shared Neighborhood Hits	126
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

PK2L1_HUMAN
θ value	0.0431538 (rank : 93)	NC score	0.283570 (rank : 32)
Query Neighborhood Hits	587	Target Neighborhood Hits	132	Shared Neighborhood Hits	43
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

PK2L2_MOUSE
θ value	0.0431538 (rank : 94)	NC score	0.268766 (rank : 33)
Query Neighborhood Hits	587	Target Neighborhood Hits	84	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

TPTE2_HUMAN
θ value	0.0431538 (rank : 95)	NC score	0.170256 (rank : 48)
Query Neighborhood Hits	587	Target Neighborhood Hits	68	Shared Neighborhood Hits	27
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

WASIP_HUMAN
θ value	0.0431538 (rank : 96)	NC score	0.084084 (rank : 97)
Query Neighborhood Hits	587	Target Neighborhood Hits	458	Shared Neighborhood Hits	104
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

MLL2_HUMAN
θ value	0.0563607 (rank : 97)	NC score	0.064420 (rank : 152)
Query Neighborhood Hits	587	Target Neighborhood Hits	1788	Shared Neighborhood Hits	245
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MN1_HUMAN
θ value	0.0563607 (rank : 98)	NC score	0.049877 (rank : 223)
Query Neighborhood Hits	587	Target Neighborhood Hits	196	Shared Neighborhood Hits	45
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

SMCA4_HUMAN
θ value	0.0563607 (rank : 99)	NC score	0.023973 (rank : 366)
Query Neighborhood Hits	587	Target Neighborhood Hits	597	Shared Neighborhood Hits	85
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

TAB3_MOUSE
θ value	0.0563607 (rank : 100)	NC score	0.058694 (rank : 180)
Query Neighborhood Hits	587	Target Neighborhood Hits	273	Shared Neighborhood Hits	75
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

AFF1_MOUSE
θ value	0.0736092 (rank : 101)	NC score	0.041797 (rank : 247)
Query Neighborhood Hits	587	Target Neighborhood Hits	351	Shared Neighborhood Hits	54
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

ATX2L_HUMAN
θ value	0.0736092 (rank : 102)	NC score	0.053470 (rank : 208)
Query Neighborhood Hits	587	Target Neighborhood Hits	443	Shared Neighborhood Hits	104
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

ELL_HUMAN
θ value	0.0736092 (rank : 103)	NC score	0.033927 (rank : 294)
Query Neighborhood Hits	587	Target Neighborhood Hits	183	Shared Neighborhood Hits	54
SwissProt Accessions	P55199	Gene names	ELL, C19orf17
Domain Architecture
Description	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein).

GGN_MOUSE
θ value	0.0736092 (rank : 104)	NC score	0.078619 (rank : 110)
Query Neighborhood Hits	587	Target Neighborhood Hits	311	Shared Neighborhood Hits	73
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

PK2L2_HUMAN
θ value	0.0736092 (rank : 105)	NC score	0.299840 (rank : 31)
Query Neighborhood Hits	587	Target Neighborhood Hits	90	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PRP5_HUMAN
θ value	0.0736092 (rank : 106)	NC score	0.097643 (rank : 74)
Query Neighborhood Hits	587	Target Neighborhood Hits	108	Shared Neighborhood Hits	38
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

PRR12_HUMAN
θ value	0.0736092 (rank : 107)	NC score	0.061710 (rank : 162)
Query Neighborhood Hits	587	Target Neighborhood Hits	460	Shared Neighborhood Hits	88
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

TARA_HUMAN
θ value	0.0736092 (rank : 108)	NC score	0.084059 (rank : 98)
Query Neighborhood Hits	587	Target Neighborhood Hits	1626	Shared Neighborhood Hits	257
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

WNK4_HUMAN
θ value	0.0736092 (rank : 109)	NC score	0.013035 (rank : 484)
Query Neighborhood Hits	587	Target Neighborhood Hits	1043	Shared Neighborhood Hits	91
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

YLPM1_HUMAN
θ value	0.0736092 (rank : 110)	NC score	0.084245 (rank : 96)
Query Neighborhood Hits	587	Target Neighborhood Hits	670	Shared Neighborhood Hits	146
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

3BP1_HUMAN
θ value	0.0961366 (rank : 111)	NC score	0.034762 (rank : 287)
Query Neighborhood Hits	587	Target Neighborhood Hits	376	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

ABI2_HUMAN
θ value	0.0961366 (rank : 112)	NC score	0.024909 (rank : 361)
Query Neighborhood Hits	587	Target Neighborhood Hits	350	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

BAT3_MOUSE
θ value	0.0961366 (rank : 113)	NC score	0.076939 (rank : 118)
Query Neighborhood Hits	587	Target Neighborhood Hits	518	Shared Neighborhood Hits	150
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

IQEC2_HUMAN
θ value	0.0961366 (rank : 114)	NC score	0.044272 (rank : 236)
Query Neighborhood Hits	587	Target Neighborhood Hits	403	Shared Neighborhood Hits	69
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_MOUSE
θ value	0.0961366 (rank : 115)	NC score	0.044859 (rank : 235)
Query Neighborhood Hits	587	Target Neighborhood Hits	417	Shared Neighborhood Hits	69
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC3_HUMAN
θ value	0.0961366 (rank : 116)	NC score	0.037014 (rank : 271)
Query Neighborhood Hits	587	Target Neighborhood Hits	125	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

IRS2_HUMAN
θ value	0.0961366 (rank : 117)	NC score	0.050184 (rank : 222)
Query Neighborhood Hits	587	Target Neighborhood Hits	262	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

MAST4_HUMAN
θ value	0.0961366 (rank : 118)	NC score	0.025040 (rank : 360)
Query Neighborhood Hits	587	Target Neighborhood Hits	1804	Shared Neighborhood Hits	242
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

PKD2_MOUSE
θ value	0.0961366 (rank : 119)	NC score	0.263361 (rank : 34)
Query Neighborhood Hits	587	Target Neighborhood Hits	99	Shared Neighborhood Hits	44
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

RIN3_MOUSE
θ value	0.0961366 (rank : 120)	NC score	0.034247 (rank : 291)
Query Neighborhood Hits	587	Target Neighborhood Hits	239	Shared Neighborhood Hits	51
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

STRC_MOUSE
θ value	0.0961366 (rank : 121)	NC score	0.028156 (rank : 331)
Query Neighborhood Hits	587	Target Neighborhood Hits	89	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VIM6	Gene names	Strc
Domain Architecture	No domain graphic available
Description	Stereocilin precursor.

TENX_HUMAN
θ value	0.0961366 (rank : 122)	NC score	0.008085 (rank : 562)
Query Neighborhood Hits	587	Target Neighborhood Hits	789	Shared Neighborhood Hits	50
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

WASIP_MOUSE
θ value	0.0961366 (rank : 123)	NC score	0.080927 (rank : 105)
Query Neighborhood Hits	587	Target Neighborhood Hits	392	Shared Neighborhood Hits	100
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

CS016_HUMAN
θ value	0.125558 (rank : 124)	NC score	0.061318 (rank : 167)
Query Neighborhood Hits	587	Target Neighborhood Hits	310	Shared Neighborhood Hits	76
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

CSKI2_HUMAN
θ value	0.125558 (rank : 125)	NC score	0.027654 (rank : 333)
Query Neighborhood Hits	587	Target Neighborhood Hits	747	Shared Neighborhood Hits	100
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

IRX1_HUMAN
θ value	0.125558 (rank : 126)	NC score	0.020447 (rank : 404)
Query Neighborhood Hits	587	Target Neighborhood Hits	285	Shared Neighborhood Hits	25
SwissProt Accessions	P78414, Q7Z2F8, Q8N312	Gene names	IRX1, IRXA1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-1 (Iroquois homeobox protein 1) (Homeodomain protein IRXA1).

MUC7_HUMAN
θ value	0.125558 (rank : 127)	NC score	0.068064 (rank : 142)
Query Neighborhood Hits	587	Target Neighborhood Hits	538	Shared Neighborhood Hits	101
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NIBL_HUMAN
θ value	0.125558 (rank : 128)	NC score	0.031556 (rank : 307)
Query Neighborhood Hits	587	Target Neighborhood Hits	61	Shared Neighborhood Hits	17
SwissProt Accessions	Q96TA1, Q9BUS2, Q9NT35	Gene names	C9orf88
Domain Architecture	No domain graphic available
Description	Niban-like protein (Meg-3).

SYN1_HUMAN
θ value	0.125558 (rank : 129)	NC score	0.060240 (rank : 171)
Query Neighborhood Hits	587	Target Neighborhood Hits	419	Shared Neighborhood Hits	98
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

CSKI1_MOUSE
θ value	0.163984 (rank : 130)	NC score	0.036967 (rank : 272)
Query Neighborhood Hits	587	Target Neighborhood Hits	1031	Shared Neighborhood Hits	203
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

K1802_MOUSE
θ value	0.163984 (rank : 131)	NC score	0.089008 (rank : 85)
Query Neighborhood Hits	587	Target Neighborhood Hits	1596	Shared Neighborhood Hits	266
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

KCNC1_HUMAN
θ value	0.163984 (rank : 132)	NC score	0.148994 (rank : 53)
Query Neighborhood Hits	587	Target Neighborhood Hits	133	Shared Neighborhood Hits	52
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC1_MOUSE
θ value	0.163984 (rank : 133)	NC score	0.147611 (rank : 54)
Query Neighborhood Hits	587	Target Neighborhood Hits	133	Shared Neighborhood Hits	52
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCND1_HUMAN
θ value	0.163984 (rank : 134)	NC score	0.154723 (rank : 51)
Query Neighborhood Hits	587	Target Neighborhood Hits	160	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

TAB3_HUMAN
θ value	0.163984 (rank : 135)	NC score	0.039132 (rank : 257)
Query Neighborhood Hits	587	Target Neighborhood Hits	168	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

TCGAP_MOUSE
θ value	0.163984 (rank : 136)	NC score	0.027700 (rank : 332)
Query Neighborhood Hits	587	Target Neighborhood Hits	409	Shared Neighborhood Hits	70
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

AATK_HUMAN
θ value	0.21417 (rank : 137)	NC score	0.021136 (rank : 393)
Query Neighborhood Hits	587	Target Neighborhood Hits	1243	Shared Neighborhood Hits	185
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

FMN2_HUMAN
θ value	0.21417 (rank : 138)	NC score	0.035564 (rank : 284)
Query Neighborhood Hits	587	Target Neighborhood Hits	484	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

IRX5_MOUSE
θ value	0.21417 (rank : 139)	NC score	0.023721 (rank : 367)
Query Neighborhood Hits	587	Target Neighborhood Hits	324	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JKQ4, Q80WV4, Q9JLL5	Gene names	Irx5, Irxb2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2).

LSR_HUMAN
θ value	0.21417 (rank : 140)	NC score	0.033549 (rank : 296)
Query Neighborhood Hits	587	Target Neighborhood Hits	45	Shared Neighborhood Hits	8
SwissProt Accessions	Q86X29, O00112, O00426, Q6ZT80, Q9UQL3	Gene names	LSR, LISCH
Domain Architecture	No domain graphic available
Description	Lipolysis-stimulated lipoprotein receptor.

LSR_MOUSE
θ value	0.21417 (rank : 141)	NC score	0.034003 (rank : 293)
Query Neighborhood Hits	587	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q99KG5, Q3TJE7, Q3UIQ9, Q61148, Q61149, Q6U816	Gene names	Lsr, Lisch7
Domain Architecture	No domain graphic available
Description	Lipolysis-stimulated lipoprotein receptor precursor (Liver-specific bHLH-Zip transcription factor) (Lipolysis-stimulated receptor) (Liver- specific gene on mouse chromosome 7 protein).

RUSC2_MOUSE
θ value	0.21417 (rank : 142)	NC score	0.058030 (rank : 184)
Query Neighborhood Hits	587	Target Neighborhood Hits	305	Shared Neighborhood Hits	88
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SFPQ_MOUSE
θ value	0.21417 (rank : 143)	NC score	0.054548 (rank : 202)
Query Neighborhood Hits	587	Target Neighborhood Hits	958	Shared Neighborhood Hits	111
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SMR1_MOUSE
θ value	0.21417 (rank : 144)	NC score	0.053535 (rank : 207)
Query Neighborhood Hits	587	Target Neighborhood Hits	103	Shared Neighborhood Hits	26
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

WBP11_HUMAN
θ value	0.21417 (rank : 145)	NC score	0.055173 (rank : 197)
Query Neighborhood Hits	587	Target Neighborhood Hits	354	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
θ value	0.21417 (rank : 146)	NC score	0.055885 (rank : 192)
Query Neighborhood Hits	587	Target Neighborhood Hits	362	Shared Neighborhood Hits	74
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

WIRE_MOUSE
θ value	0.21417 (rank : 147)	NC score	0.057530 (rank : 186)
Query Neighborhood Hits	587	Target Neighborhood Hits	310	Shared Neighborhood Hits	76
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

EP300_HUMAN
θ value	0.279714 (rank : 148)	NC score	0.059622 (rank : 177)
Query Neighborhood Hits	587	Target Neighborhood Hits	821	Shared Neighborhood Hits	169
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

IL3RB_HUMAN
θ value	0.279714 (rank : 149)	NC score	0.027497 (rank : 335)
Query Neighborhood Hits	587	Target Neighborhood Hits	163	Shared Neighborhood Hits	36
SwissProt Accessions	P32927	Gene names	CSF2RB, IL3RB, IL5RB
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen) (CDw131).

KCND2_HUMAN
θ value	0.279714 (rank : 150)	NC score	0.173093 (rank : 47)
Query Neighborhood Hits	587	Target Neighborhood Hits	154	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_MOUSE
θ value	0.279714 (rank : 151)	NC score	0.173494 (rank : 46)
Query Neighborhood Hits	587	Target Neighborhood Hits	156	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

SHAN1_HUMAN
θ value	0.279714 (rank : 152)	NC score	0.029709 (rank : 320)
Query Neighborhood Hits	587	Target Neighborhood Hits	1041	Shared Neighborhood Hits	131
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

TARSH_HUMAN
θ value	0.279714 (rank : 153)	NC score	0.087041 (rank : 89)
Query Neighborhood Hits	587	Target Neighborhood Hits	768	Shared Neighborhood Hits	204
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TM131_MOUSE
θ value	0.279714 (rank : 154)	NC score	0.039063 (rank : 260)
Query Neighborhood Hits	587	Target Neighborhood Hits	156	Shared Neighborhood Hits	29
SwissProt Accessions	O70472	Gene names	Tmem131, D1Bwg0491e, Rw1
Domain Architecture	No domain graphic available
Description	Transmembrane protein 131 (Protein RW1).

YTHD2_HUMAN
θ value	0.279714 (rank : 155)	NC score	0.022429 (rank : 381)
Query Neighborhood Hits	587	Target Neighborhood Hits	89	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y5A9, Q5VSZ9, Q8TDH0, Q9BUJ5	Gene names	YTHDF2, HGRG8
Domain Architecture
Description	YTH domain family protein 2 (High-glucose-regulated protein 8) (NY- REN-2 antigen) (CLL-associated antigen KW-14).

ZYX_HUMAN
θ value	0.279714 (rank : 156)	NC score	0.023230 (rank : 371)
Query Neighborhood Hits	587	Target Neighborhood Hits	387	Shared Neighborhood Hits	56
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

AFF1_HUMAN
θ value	0.365318 (rank : 157)	NC score	0.054573 (rank : 201)
Query Neighborhood Hits	587	Target Neighborhood Hits	506	Shared Neighborhood Hits	88
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

DLGP3_HUMAN
θ value	0.365318 (rank : 158)	NC score	0.021582 (rank : 389)
Query Neighborhood Hits	587	Target Neighborhood Hits	55	Shared Neighborhood Hits	13
SwissProt Accessions	O95886, Q5TDD5, Q9H3X7	Gene names	DLGAP3, DAP3
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 3 (DAP-3) (SAP90/PSD-95-associated protein 3) (SAPAP3) (PSD-95/SAP90-binding protein 3).

DUS8_HUMAN
θ value	0.365318 (rank : 159)	NC score	0.012961 (rank : 486)
Query Neighborhood Hits	587	Target Neighborhood Hits	161	Shared Neighborhood Hits	26
SwissProt Accessions	Q13202	Gene names	DUSP8, VH5
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH-5).

HCN4_MOUSE
θ value	0.365318 (rank : 160)	NC score	0.038139 (rank : 266)
Query Neighborhood Hits	587	Target Neighborhood Hits	284	Shared Neighborhood Hits	61
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HXD3_HUMAN
θ value	0.365318 (rank : 161)	NC score	0.016204 (rank : 442)
Query Neighborhood Hits	587	Target Neighborhood Hits	433	Shared Neighborhood Hits	57
SwissProt Accessions	P31249, Q99955, Q9BSC5	Gene names	HOXD3, HOX4A
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4A).

MUCDL_MOUSE
θ value	0.365318 (rank : 162)	NC score	0.026632 (rank : 343)
Query Neighborhood Hits	587	Target Neighborhood Hits	461	Shared Neighborhood Hits	79
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

PCLO_MOUSE
θ value	0.365318 (rank : 163)	NC score	0.091236 (rank : 80)
Query Neighborhood Hits	587	Target Neighborhood Hits	2275	Shared Neighborhood Hits	345
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PCQAP_MOUSE
θ value	0.365318 (rank : 164)	NC score	0.041131 (rank : 249)
Query Neighborhood Hits	587	Target Neighborhood Hits	506	Shared Neighborhood Hits	79
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

PKDRE_HUMAN
θ value	0.365318 (rank : 165)	NC score	0.101955 (rank : 68)
Query Neighborhood Hits	587	Target Neighborhood Hits	64	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

PRB4S_HUMAN
θ value	0.365318 (rank : 166)	NC score	0.068174 (rank : 141)
Query Neighborhood Hits	587	Target Neighborhood Hits	330	Shared Neighborhood Hits	79
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

RGP2_HUMAN
θ value	0.365318 (rank : 167)	NC score	0.018434 (rank : 425)
Query Neighborhood Hits	587	Target Neighborhood Hits	60	Shared Neighborhood Hits	10
SwissProt Accessions	P47736	Gene names	RAP1GAP, RAP1GA1
Domain Architecture
Description	Rap1 GTPase-activating protein 1 (Rap1GAP).

SHAN2_MOUSE
θ value	0.365318 (rank : 168)	NC score	0.033074 (rank : 300)
Query Neighborhood Hits	587	Target Neighborhood Hits	446	Shared Neighborhood Hits	61
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SNIP_MOUSE
θ value	0.365318 (rank : 169)	NC score	0.036910 (rank : 273)
Query Neighborhood Hits	587	Target Neighborhood Hits	319	Shared Neighborhood Hits	58
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

ZDHC8_HUMAN
θ value	0.365318 (rank : 170)	NC score	0.029930 (rank : 318)
Query Neighborhood Hits	587	Target Neighborhood Hits	234	Shared Neighborhood Hits	74
SwissProt Accessions	Q9ULC8, Q6ICL1, Q6ZNF5, Q7Z6L9	Gene names	ZDHHC8, KIAA1292, ZDHHCL1, ZNF378
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8) (Zinc finger protein 378).

ZN628_HUMAN
θ value	0.365318 (rank : 171)	NC score	-0.003060 (rank : 645)
Query Neighborhood Hits	587	Target Neighborhood Hits	814	Shared Neighborhood Hits	38
SwissProt Accessions	Q5EBL2, Q86X34	Gene names	ZNF628
Domain Architecture	No domain graphic available
Description	Zinc finger protein 628.

ZO1_MOUSE
θ value	0.365318 (rank : 172)	NC score	0.018911 (rank : 419)
Query Neighborhood Hits	587	Target Neighborhood Hits	453	Shared Neighborhood Hits	65
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

CCNT1_MOUSE
θ value	0.47712 (rank : 173)	NC score	0.014789 (rank : 457)
Query Neighborhood Hits	587	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QWV9, Q9Z0U7	Gene names	Ccnt1
Domain Architecture
Description	Cyclin-T1 (CycT1) (Cyclin-T).

CENG1_HUMAN
θ value	0.47712 (rank : 174)	NC score	0.015755 (rank : 448)
Query Neighborhood Hits	587	Target Neighborhood Hits	544	Shared Neighborhood Hits	52
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

DIDO1_HUMAN
θ value	0.47712 (rank : 175)	NC score	0.086666 (rank : 91)
Query Neighborhood Hits	587	Target Neighborhood Hits	960	Shared Neighborhood Hits	205
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

EP15R_HUMAN
θ value	0.47712 (rank : 176)	NC score	0.009536 (rank : 535)
Query Neighborhood Hits	587	Target Neighborhood Hits	1083	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

FBLN2_MOUSE
θ value	0.47712 (rank : 177)	NC score	0.007597 (rank : 571)
Query Neighborhood Hits	587	Target Neighborhood Hits	505	Shared Neighborhood Hits	65
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

HXA3_HUMAN
θ value	0.47712 (rank : 178)	NC score	0.018918 (rank : 418)
Query Neighborhood Hits	587	Target Neighborhood Hits	535	Shared Neighborhood Hits	65
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

KSR1_MOUSE
θ value	0.47712 (rank : 179)	NC score	0.005281 (rank : 593)
Query Neighborhood Hits	587	Target Neighborhood Hits	870	Shared Neighborhood Hits	36
SwissProt Accessions	Q61097, Q61648, Q78DX8	Gene names	Ksr1, Ksr
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein).

NEB2_MOUSE
θ value	0.47712 (rank : 180)	NC score	0.016261 (rank : 441)
Query Neighborhood Hits	587	Target Neighborhood Hits	889	Shared Neighborhood Hits	47
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NFH_MOUSE
θ value	0.47712 (rank : 181)	NC score	0.077125 (rank : 116)
Query Neighborhood Hits	587	Target Neighborhood Hits	2247	Shared Neighborhood Hits	320
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PPRB_HUMAN
θ value	0.47712 (rank : 182)	NC score	0.039907 (rank : 253)
Query Neighborhood Hits	587	Target Neighborhood Hits	311	Shared Neighborhood Hits	62
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

RUSC2_HUMAN
θ value	0.47712 (rank : 183)	NC score	0.037166 (rank : 269)
Query Neighborhood Hits	587	Target Neighborhood Hits	205	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SMOO_HUMAN
θ value	0.47712 (rank : 184)	NC score	0.044077 (rank : 237)
Query Neighborhood Hits	587	Target Neighborhood Hits	391	Shared Neighborhood Hits	87
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

UBP21_HUMAN
θ value	0.47712 (rank : 185)	NC score	0.008398 (rank : 554)
Query Neighborhood Hits	587	Target Neighborhood Hits	95	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

ADA15_HUMAN
θ value	0.62314 (rank : 186)	NC score	0.005178 (rank : 594)
Query Neighborhood Hits	587	Target Neighborhood Hits	288	Shared Neighborhood Hits	14
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

AKAP2_MOUSE
θ value	0.62314 (rank : 187)	NC score	0.035854 (rank : 282)
Query Neighborhood Hits	587	Target Neighborhood Hits	385	Shared Neighborhood Hits	63
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

ASTN_MOUSE
θ value	0.62314 (rank : 188)	NC score	0.018835 (rank : 420)
Query Neighborhood Hits	587	Target Neighborhood Hits	98	Shared Neighborhood Hits	4
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

AUTS2_HUMAN
θ value	0.62314 (rank : 189)	NC score	0.042069 (rank : 244)
Query Neighborhood Hits	587	Target Neighborhood Hits	342	Shared Neighborhood Hits	66
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

BRDT_MOUSE
θ value	0.62314 (rank : 190)	NC score	0.026336 (rank : 347)
Query Neighborhood Hits	587	Target Neighborhood Hits	243	Shared Neighborhood Hits	26
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

FBLI1_HUMAN
θ value	0.62314 (rank : 191)	NC score	0.012890 (rank : 488)
Query Neighborhood Hits	587	Target Neighborhood Hits	200	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WUP2, Q5VVE0, Q5VVE1, Q8IX23, Q96T00, Q9UFD6	Gene names	FBLIM1, FBLP1
Domain Architecture
Description	Filamin-binding LIM protein 1 (Filamin-binding LIM protein 1) (FBLP-1) (Mitogen-inducible 2-interacting protein) (MIG2-interacting protein) (Migfilin).

K0141_MOUSE
θ value	0.62314 (rank : 192)	NC score	0.020975 (rank : 395)
Query Neighborhood Hits	587	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DCV6, Q6A0B8	Gene names	Kiaa0141
Domain Architecture
Description	Protein KIAA0141.

KCND1_MOUSE
θ value	0.62314 (rank : 193)	NC score	0.154782 (rank : 50)
Query Neighborhood Hits	587	Target Neighborhood Hits	165	Shared Neighborhood Hits	59
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCNG3_MOUSE
θ value	0.62314 (rank : 194)	NC score	0.111613 (rank : 66)
Query Neighborhood Hits	587	Target Neighborhood Hits	91	Shared Neighborhood Hits	43
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNQ3_HUMAN
θ value	0.62314 (rank : 195)	NC score	0.062308 (rank : 160)
Query Neighborhood Hits	587	Target Neighborhood Hits	114	Shared Neighborhood Hits	37
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_MOUSE
θ value	0.62314 (rank : 196)	NC score	0.061321 (rank : 166)
Query Neighborhood Hits	587	Target Neighborhood Hits	105	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

M3K9_HUMAN
θ value	0.62314 (rank : 197)	NC score	0.005671 (rank : 589)
Query Neighborhood Hits	587	Target Neighborhood Hits	1123	Shared Neighborhood Hits	59
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

MYPN_MOUSE
θ value	0.62314 (rank : 198)	NC score	0.008278 (rank : 555)
Query Neighborhood Hits	587	Target Neighborhood Hits	421	Shared Neighborhood Hits	29
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

NACAM_MOUSE
θ value	0.62314 (rank : 199)	NC score	0.109324 (rank : 67)
Query Neighborhood Hits	587	Target Neighborhood Hits	1866	Shared Neighborhood Hits	336
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PCD12_HUMAN
θ value	0.62314 (rank : 200)	NC score	0.000537 (rank : 632)
Query Neighborhood Hits	587	Target Neighborhood Hits	203	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NPG4, Q6UXB6, Q96KB8, Q9H7Y6, Q9H8E0	Gene names	PCDH12
Domain Architecture
Description	Protocadherin-12 precursor (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cadherin-2) (VE-cad-2).

PDZD2_HUMAN
θ value	0.62314 (rank : 201)	NC score	0.054530 (rank : 203)
Query Neighborhood Hits	587	Target Neighborhood Hits	772	Shared Neighborhood Hits	160
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PK1L1_HUMAN
θ value	0.62314 (rank : 202)	NC score	0.051110 (rank : 216)
Query Neighborhood Hits	587	Target Neighborhood Hits	140	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

PRR11_HUMAN
θ value	0.62314 (rank : 203)	NC score	0.027045 (rank : 340)
Query Neighborhood Hits	587	Target Neighborhood Hits	27	Shared Neighborhood Hits	13
SwissProt Accessions	Q96HE9, Q9NUZ7, Q9NXE9	Gene names	PRR11
Domain Architecture	No domain graphic available
Description	Proline-rich protein 11.

SF01_HUMAN
θ value	0.62314 (rank : 204)	NC score	0.031228 (rank : 308)
Query Neighborhood Hits	587	Target Neighborhood Hits	287	Shared Neighborhood Hits	58
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SON_MOUSE
θ value	0.62314 (rank : 205)	NC score	0.064046 (rank : 155)
Query Neighborhood Hits	587	Target Neighborhood Hits	957	Shared Neighborhood Hits	191
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

ZIMP7_MOUSE
θ value	0.62314 (rank : 206)	NC score	0.059699 (rank : 176)
Query Neighborhood Hits	587	Target Neighborhood Hits	566	Shared Neighborhood Hits	171
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ARI1A_HUMAN
θ value	0.813845 (rank : 207)	NC score	0.066000 (rank : 147)
Query Neighborhood Hits	587	Target Neighborhood Hits	787	Shared Neighborhood Hits	165
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

BAT3_HUMAN
θ value	0.813845 (rank : 208)	NC score	0.073399 (rank : 127)
Query Neighborhood Hits	587	Target Neighborhood Hits	490	Shared Neighborhood Hits	154
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BRD4_HUMAN
θ value	0.813845 (rank : 209)	NC score	0.039826 (rank : 255)
Query Neighborhood Hits	587	Target Neighborhood Hits	851	Shared Neighborhood Hits	113
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

C8AP2_MOUSE
θ value	0.813845 (rank : 210)	NC score	0.019166 (rank : 415)
Query Neighborhood Hits	587	Target Neighborhood Hits	405	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

CHSS3_HUMAN
θ value	0.813845 (rank : 211)	NC score	0.018503 (rank : 423)
Query Neighborhood Hits	587	Target Neighborhood Hits	97	Shared Neighborhood Hits	12
SwissProt Accessions	Q70JA7, Q76L22, Q86Y52	Gene names	CSS3, CHSY2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 3 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase II) (Chondroitin synthase 2) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II) (Carbohydrate synthase 2).

COHA1_MOUSE
θ value	0.813845 (rank : 212)	NC score	0.033273 (rank : 297)
Query Neighborhood Hits	587	Target Neighborhood Hits	414	Shared Neighborhood Hits	85
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

CT055_HUMAN
θ value	0.813845 (rank : 213)	NC score	0.025589 (rank : 355)
Query Neighborhood Hits	587	Target Neighborhood Hits	42	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BQ89	Gene names	C20orf55
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf55.

CTGE2_HUMAN
θ value	0.813845 (rank : 214)	NC score	0.009060 (rank : 539)
Query Neighborhood Hits	587	Target Neighborhood Hits	594	Shared Neighborhood Hits	21
SwissProt Accessions	Q96RT6	Gene names	CTAGE1, CTAGE2
Domain Architecture	No domain graphic available
Description	Protein cTAGE-2.

DLGP3_MOUSE
θ value	0.813845 (rank : 215)	NC score	0.019770 (rank : 410)
Query Neighborhood Hits	587	Target Neighborhood Hits	56	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PFD5, Q6PDX0, Q6XBF2	Gene names	Dlgap3, Dap3
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 3 (DAP-3) (SAP90/PSD-95-associated protein 3) (SAPAP3) (PSD-95/SAP90-binding protein 3).

EP400_MOUSE
θ value	0.813845 (rank : 216)	NC score	0.028582 (rank : 330)
Query Neighborhood Hits	587	Target Neighborhood Hits	592	Shared Neighborhood Hits	116
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

F8I2_HUMAN
θ value	0.813845 (rank : 217)	NC score	0.022452 (rank : 380)
Query Neighborhood Hits	587	Target Neighborhood Hits	17	Shared Neighborhood Hits	5
SwissProt Accessions	P23610, Q8IXP3	Gene names	F8A1, F8A
Domain Architecture	No domain graphic available
Description	Factor VIII intron 22 protein (CpG island protein).

FMN1A_MOUSE
θ value	0.813845 (rank : 218)	NC score	0.038879 (rank : 262)
Query Neighborhood Hits	587	Target Neighborhood Hits	423	Shared Neighborhood Hits	73
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

GAK_HUMAN
θ value	0.813845 (rank : 219)	NC score	0.009547 (rank : 534)
Query Neighborhood Hits	587	Target Neighborhood Hits	1028	Shared Neighborhood Hits	95
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

HCN2_MOUSE
θ value	0.813845 (rank : 220)	NC score	0.029464 (rank : 327)
Query Neighborhood Hits	587	Target Neighborhood Hits	278	Shared Neighborhood Hits	67
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

LEUK_MOUSE
θ value	0.813845 (rank : 221)	NC score	0.035455 (rank : 286)
Query Neighborhood Hits	587	Target Neighborhood Hits	147	Shared Neighborhood Hits	34
SwissProt Accessions	P15702	Gene names	Spn
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Ly- 48) (B cell differentiation antigen LP-3) (CD43 antigen).

MKL1_HUMAN
θ value	0.813845 (rank : 222)	NC score	0.025232 (rank : 358)
Query Neighborhood Hits	587	Target Neighborhood Hits	232	Shared Neighborhood Hits	37
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

MLL3_MOUSE
θ value	0.813845 (rank : 223)	NC score	0.083851 (rank : 100)
Query Neighborhood Hits	587	Target Neighborhood Hits	1399	Shared Neighborhood Hits	243
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NCOR2_HUMAN
θ value	0.813845 (rank : 224)	NC score	0.047273 (rank : 228)
Query Neighborhood Hits	587	Target Neighborhood Hits	870	Shared Neighborhood Hits	130
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

PDC6I_HUMAN
θ value	0.813845 (rank : 225)	NC score	0.042467 (rank : 243)
Query Neighborhood Hits	587	Target Neighborhood Hits	278	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

PI5PA_HUMAN
θ value	0.813845 (rank : 226)	NC score	0.069885 (rank : 137)
Query Neighborhood Hits	587	Target Neighborhood Hits	749	Shared Neighborhood Hits	215
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PKD2_HUMAN
θ value	0.813845 (rank : 227)	NC score	0.248595 (rank : 35)
Query Neighborhood Hits	587	Target Neighborhood Hits	105	Shared Neighborhood Hits	44
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

REXO1_HUMAN
θ value	0.813845 (rank : 228)	NC score	0.034613 (rank : 288)
Query Neighborhood Hits	587	Target Neighborhood Hits	242	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

RXRB_HUMAN
θ value	0.813845 (rank : 229)	NC score	0.005626 (rank : 590)
Query Neighborhood Hits	587	Target Neighborhood Hits	280	Shared Neighborhood Hits	45
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

SRR35_HUMAN
θ value	0.813845 (rank : 230)	NC score	0.013371 (rank : 476)
Query Neighborhood Hits	587	Target Neighborhood Hits	215	Shared Neighborhood Hits	16
SwissProt Accessions	Q8WXF0, Q8WW25	Gene names	SRRP35
Domain Architecture
Description	35 kDa SR repressor protein (SRrp35).

SYNJ1_MOUSE
θ value	0.813845 (rank : 231)	NC score	0.045884 (rank : 232)
Query Neighborhood Hits	587	Target Neighborhood Hits	516	Shared Neighborhood Hits	127
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TCGAP_HUMAN
θ value	0.813845 (rank : 232)	NC score	0.074779 (rank : 122)
Query Neighborhood Hits	587	Target Neighborhood Hits	872	Shared Neighborhood Hits	225
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TRPM2_MOUSE
θ value	0.813845 (rank : 233)	NC score	0.021783 (rank : 385)
Query Neighborhood Hits	587	Target Neighborhood Hits	61	Shared Neighborhood Hits	11
SwissProt Accessions	Q91YD4	Gene names	Trpm2, Ltrpc2, Trpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7).

BCOR_HUMAN
θ value	1.06291 (rank : 234)	NC score	0.027113 (rank : 339)
Query Neighborhood Hits	587	Target Neighborhood Hits	609	Shared Neighborhood Hits	87
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CMTA2_MOUSE
θ value	1.06291 (rank : 235)	NC score	0.020570 (rank : 402)
Query Neighborhood Hits	587	Target Neighborhood Hits	216	Shared Neighborhood Hits	31
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CO2A1_HUMAN
θ value	1.06291 (rank : 236)	NC score	0.030629 (rank : 312)
Query Neighborhood Hits	587	Target Neighborhood Hits	486	Shared Neighborhood Hits	113
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CPSF7_MOUSE
θ value	1.06291 (rank : 237)	NC score	0.031049 (rank : 310)
Query Neighborhood Hits	587	Target Neighborhood Hits	123	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BTV2, Q3TNF1, Q8BKE7, Q8CFS8	Gene names	Cpsf7
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 7.

DEN1A_HUMAN
θ value	1.06291 (rank : 238)	NC score	0.020691 (rank : 398)
Query Neighborhood Hits	587	Target Neighborhood Hits	176	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

FILA_HUMAN
θ value	1.06291 (rank : 239)	NC score	0.036502 (rank : 278)
Query Neighborhood Hits	587	Target Neighborhood Hits	685	Shared Neighborhood Hits	68
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

FOG1_HUMAN
θ value	1.06291 (rank : 240)	NC score	0.014091 (rank : 466)
Query Neighborhood Hits	587	Target Neighborhood Hits	981	Shared Neighborhood Hits	94
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

FOXGA_HUMAN
θ value	1.06291 (rank : 241)	NC score	0.008642 (rank : 548)
Query Neighborhood Hits	587	Target Neighborhood Hits	132	Shared Neighborhood Hits	17
SwissProt Accessions	P55316	Gene names	FOXG1A, FKHL2
Domain Architecture
Description	Forkhead box protein G1A (Forkhead-related protein FKHL2) (Transcription factor BF-2) (Brain factor 2) (BF2) (HFK2).

HRX_HUMAN
θ value	1.06291 (rank : 242)	NC score	0.043081 (rank : 241)
Query Neighborhood Hits	587	Target Neighborhood Hits	825	Shared Neighborhood Hits	108
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

M3K1_MOUSE
θ value	1.06291 (rank : 243)	NC score	0.002980 (rank : 616)
Query Neighborhood Hits	587	Target Neighborhood Hits	952	Shared Neighborhood Hits	48
SwissProt Accessions	P53349, Q60831, Q9R0U3, Q9R256	Gene names	Map3k1, Mekk, Mekk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1).

MAST1_MOUSE
θ value	1.06291 (rank : 244)	NC score	0.004599 (rank : 602)
Query Neighborhood Hits	587	Target Neighborhood Hits	1123	Shared Neighborhood Hits	76
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MK07_MOUSE
θ value	1.06291 (rank : 245)	NC score	0.002945 (rank : 617)
Query Neighborhood Hits	587	Target Neighborhood Hits	1054	Shared Neighborhood Hits	75
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

NOLC1_HUMAN
θ value	1.06291 (rank : 246)	NC score	0.036634 (rank : 277)
Query Neighborhood Hits	587	Target Neighborhood Hits	452	Shared Neighborhood Hits	63
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

OTX1_HUMAN
θ value	1.06291 (rank : 247)	NC score	0.008213 (rank : 557)
Query Neighborhood Hits	587	Target Neighborhood Hits	379	Shared Neighborhood Hits	26
SwissProt Accessions	P32242, Q53TG6	Gene names	OTX1
Domain Architecture
Description	Homeobox protein OTX1.

PHLPP_MOUSE
θ value	1.06291 (rank : 248)	NC score	0.004757 (rank : 599)
Query Neighborhood Hits	587	Target Neighborhood Hits	394	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

PRGC2_HUMAN
θ value	1.06291 (rank : 249)	NC score	0.039443 (rank : 256)
Query Neighborhood Hits	587	Target Neighborhood Hits	272	Shared Neighborhood Hits	65
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

SHC1_MOUSE
θ value	1.06291 (rank : 250)	NC score	0.011990 (rank : 498)
Query Neighborhood Hits	587	Target Neighborhood Hits	180	Shared Neighborhood Hits	18
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SMRC1_HUMAN
θ value	1.06291 (rank : 251)	NC score	0.020577 (rank : 401)
Query Neighborhood Hits	587	Target Neighborhood Hits	375	Shared Neighborhood Hits	50
SwissProt Accessions	Q92922, Q6P172, Q8IWH2	Gene names	SMARCC1, BAF155
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155).

WASP_HUMAN
θ value	1.06291 (rank : 252)	NC score	0.033201 (rank : 298)
Query Neighborhood Hits	587	Target Neighborhood Hits	195	Shared Neighborhood Hits	55
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

WDR33_HUMAN
θ value	1.06291 (rank : 253)	NC score	0.014448 (rank : 464)
Query Neighborhood Hits	587	Target Neighborhood Hits	638	Shared Neighborhood Hits	81
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

BAI1_HUMAN
θ value	1.38821 (rank : 254)	NC score	0.006753 (rank : 579)
Query Neighborhood Hits	587	Target Neighborhood Hits	375	Shared Neighborhood Hits	48
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BCL9_HUMAN
θ value	1.38821 (rank : 255)	NC score	0.097473 (rank : 75)
Query Neighborhood Hits	587	Target Neighborhood Hits	1008	Shared Neighborhood Hits	249
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CNOT3_MOUSE
θ value	1.38821 (rank : 256)	NC score	0.037155 (rank : 270)
Query Neighborhood Hits	587	Target Neighborhood Hits	504	Shared Neighborhood Hits	72
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

COIA1_HUMAN
θ value	1.38821 (rank : 257)	NC score	0.029680 (rank : 321)
Query Neighborhood Hits	587	Target Neighborhood Hits	447	Shared Neighborhood Hits	105
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CPSF7_HUMAN
θ value	1.38821 (rank : 258)	NC score	0.030429 (rank : 314)
Query Neighborhood Hits	587	Target Neighborhood Hits	125	Shared Neighborhood Hits	27
SwissProt Accessions	Q8N684, Q7Z3H9, Q9H025, Q9H9V1	Gene names	CPSF7
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 7 (Cleavage and polyadenylation specificity factor 59 kDa subunit) (CPSF 59 kDa subunit) (Pre-mRNA cleavage factor Im 59 kDa subunit).

DDEF1_MOUSE
θ value	1.38821 (rank : 259)	NC score	0.013419 (rank : 475)
Query Neighborhood Hits	587	Target Neighborhood Hits	592	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DOT1L_HUMAN
θ value	1.38821 (rank : 260)	NC score	0.056570 (rank : 191)
Query Neighborhood Hits	587	Target Neighborhood Hits	660	Shared Neighborhood Hits	129
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

FBX46_MOUSE
θ value	1.38821 (rank : 261)	NC score	0.030974 (rank : 311)
Query Neighborhood Hits	587	Target Neighborhood Hits	139	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BG80	Gene names	Fbxo46, Fbx46, Fbxo34l
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

GCX1_HUMAN
θ value	1.38821 (rank : 262)	NC score	0.021556 (rank : 390)
Query Neighborhood Hits	587	Target Neighborhood Hits	132	Shared Neighborhood Hits	22
SwissProt Accessions	Q96NM4, Q5TE33, Q5TE34, Q5TE35, Q96IC9, Q9BQN5	Gene names	GCX1, C20orf100
Domain Architecture
Description	Granulosa cell HMG box protein 1 (GCX-1).

JADE2_HUMAN
θ value	1.38821 (rank : 263)	NC score	0.013187 (rank : 482)
Query Neighborhood Hits	587	Target Neighborhood Hits	199	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

JHD2C_MOUSE
θ value	1.38821 (rank : 264)	NC score	0.011939 (rank : 499)
Query Neighborhood Hits	587	Target Neighborhood Hits	297	Shared Neighborhood Hits	33
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

KCNG3_HUMAN
θ value	1.38821 (rank : 265)	NC score	0.112360 (rank : 65)
Query Neighborhood Hits	587	Target Neighborhood Hits	91	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KLF2_HUMAN
θ value	1.38821 (rank : 266)	NC score	-0.000578 (rank : 636)
Query Neighborhood Hits	587	Target Neighborhood Hits	755	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y5W3, Q9UJS5, Q9UKR6	Gene names	KLF2, LKLF
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 2 (Lung krueppel-like factor).

MCLN2_MOUSE
θ value	1.38821 (rank : 267)	NC score	0.060051 (rank : 174)
Query Neighborhood Hits	587	Target Neighborhood Hits	31	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K595, Q3UCG4, Q8K2T6, Q9CQD3	Gene names	Mcoln2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

MINT_HUMAN
θ value	1.38821 (rank : 268)	NC score	0.046943 (rank : 229)
Query Neighborhood Hits	587	Target Neighborhood Hits	1291	Shared Neighborhood Hits	153
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NFAT5_MOUSE
θ value	1.38821 (rank : 269)	NC score	0.011503 (rank : 506)
Query Neighborhood Hits	587	Target Neighborhood Hits	162	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

PDC6I_MOUSE
θ value	1.38821 (rank : 270)	NC score	0.035547 (rank : 285)
Query Neighborhood Hits	587	Target Neighborhood Hits	275	Shared Neighborhood Hits	48
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

PER1_HUMAN
θ value	1.38821 (rank : 271)	NC score	0.016832 (rank : 437)
Query Neighborhood Hits	587	Target Neighborhood Hits	215	Shared Neighborhood Hits	45
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

SP2_HUMAN
θ value	1.38821 (rank : 272)	NC score	-0.001602 (rank : 641)
Query Neighborhood Hits	587	Target Neighborhood Hits	747	Shared Neighborhood Hits	32
SwissProt Accessions	Q02086	Gene names	SP2, KIAA0048
Domain Architecture
Description	Transcription factor Sp2.

SYN1_MOUSE
θ value	1.38821 (rank : 273)	NC score	0.050301 (rank : 220)
Query Neighborhood Hits	587	Target Neighborhood Hits	363	Shared Neighborhood Hits	80
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

SYNJ1_HUMAN
θ value	1.38821 (rank : 274)	NC score	0.038183 (rank : 265)
Query Neighborhood Hits	587	Target Neighborhood Hits	498	Shared Neighborhood Hits	121
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SYT3_MOUSE
θ value	1.38821 (rank : 275)	NC score	0.006694 (rank : 580)
Query Neighborhood Hits	587	Target Neighborhood Hits	147	Shared Neighborhood Hits	11
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

UBP42_HUMAN
θ value	1.38821 (rank : 276)	NC score	0.023076 (rank : 373)
Query Neighborhood Hits	587	Target Neighborhood Hits	445	Shared Neighborhood Hits	90
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

ZN516_MOUSE
θ value	1.38821 (rank : 277)	NC score	0.018312 (rank : 426)
Query Neighborhood Hits	587	Target Neighborhood Hits	1197	Shared Neighborhood Hits	185
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

ZN628_MOUSE
θ value	1.38821 (rank : 278)	NC score	-0.003140 (rank : 646)
Query Neighborhood Hits	587	Target Neighborhood Hits	815	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CJ78, Q3U2L5, Q6P5B3	Gene names	Znf628, Zec, Zfp628
Domain Architecture	No domain graphic available
Description	Zinc finger protein 628 (Zinc finger protein expressed in embryonal cells and certain adult organs).

ADA15_MOUSE
θ value	1.81305 (rank : 279)	NC score	0.005573 (rank : 591)
Query Neighborhood Hits	587	Target Neighborhood Hits	324	Shared Neighborhood Hits	22
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ALEX_HUMAN
θ value	1.81305 (rank : 280)	NC score	0.058300 (rank : 182)
Query Neighborhood Hits	587	Target Neighborhood Hits	361	Shared Neighborhood Hits	98
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ALEX_MOUSE
θ value	1.81305 (rank : 281)	NC score	0.041664 (rank : 248)
Query Neighborhood Hits	587	Target Neighborhood Hits	197	Shared Neighborhood Hits	54
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

APBA3_MOUSE
θ value	1.81305 (rank : 282)	NC score	0.012296 (rank : 493)
Query Neighborhood Hits	587	Target Neighborhood Hits	174	Shared Neighborhood Hits	21
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

BCOR_MOUSE
θ value	1.81305 (rank : 283)	NC score	0.022272 (rank : 383)
Query Neighborhood Hits	587	Target Neighborhood Hits	521	Shared Neighborhood Hits	71
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CPSF6_HUMAN
θ value	1.81305 (rank : 284)	NC score	0.046909 (rank : 230)
Query Neighborhood Hits	587	Target Neighborhood Hits	359	Shared Neighborhood Hits	83
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	1.81305 (rank : 285)	NC score	0.049756 (rank : 224)
Query Neighborhood Hits	587	Target Neighborhood Hits	356	Shared Neighborhood Hits	83
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CSKI2_MOUSE
θ value	1.81305 (rank : 286)	NC score	0.027018 (rank : 341)
Query Neighborhood Hits	587	Target Neighborhood Hits	812	Shared Neighborhood Hits	148
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CTGE5_HUMAN
θ value	1.81305 (rank : 287)	NC score	0.008124 (rank : 559)
Query Neighborhood Hits	587	Target Neighborhood Hits	800	Shared Neighborhood Hits	36
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

DEN4C_HUMAN
θ value	1.81305 (rank : 288)	NC score	0.012991 (rank : 485)
Query Neighborhood Hits	587	Target Neighborhood Hits	63	Shared Neighborhood Hits	8
SwissProt Accessions	Q5VZ89, Q6AI48, Q6ZUB3, Q8NCY7, Q9H6N4, Q9NUT1, Q9NWA5	Gene names	DENND4C, C9orf55
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 4C.

EP15R_MOUSE
θ value	1.81305 (rank : 289)	NC score	0.010068 (rank : 524)
Query Neighborhood Hits	587	Target Neighborhood Hits	1135	Shared Neighborhood Hits	56
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

FIGN_HUMAN
θ value	1.81305 (rank : 290)	NC score	0.010320 (rank : 522)
Query Neighborhood Hits	587	Target Neighborhood Hits	176	Shared Neighborhood Hits	23
SwissProt Accessions	Q5HY92, Q9H6M5, Q9NVZ9	Gene names	FIGN
Domain Architecture	No domain graphic available
Description	Fidgetin.

GRIN1_HUMAN
θ value	1.81305 (rank : 291)	NC score	0.069973 (rank : 136)
Query Neighborhood Hits	587	Target Neighborhood Hits	681	Shared Neighborhood Hits	174
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

HGS_MOUSE
θ value	1.81305 (rank : 292)	NC score	0.026329 (rank : 348)
Query Neighborhood Hits	587	Target Neighborhood Hits	589	Shared Neighborhood Hits	95
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

INSM1_MOUSE
θ value	1.81305 (rank : 293)	NC score	0.001717 (rank : 622)
Query Neighborhood Hits	587	Target Neighborhood Hits	678	Shared Neighborhood Hits	25
SwissProt Accessions	Q63ZV0, Q9Z113	Gene names	Insm1, Ia1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

MEGF8_MOUSE
θ value	1.81305 (rank : 294)	NC score	0.007978 (rank : 564)
Query Neighborhood Hits	587	Target Neighborhood Hits	520	Shared Neighborhood Hits	15
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MYH4_MOUSE
θ value	1.81305 (rank : 295)	NC score	-0.002563 (rank : 644)
Query Neighborhood Hits	587	Target Neighborhood Hits	1476	Shared Neighborhood Hits	56
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYRIP_MOUSE
θ value	1.81305 (rank : 296)	NC score	0.014532 (rank : 463)
Query Neighborhood Hits	587	Target Neighborhood Hits	207	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

NAT6_HUMAN
θ value	1.81305 (rank : 297)	NC score	0.017902 (rank : 431)
Query Neighborhood Hits	587	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q93015, Q93014	Gene names	NAT6, FUS2
Domain Architecture
Description	N-acetyltransferase 6 (EC 2.3.1.-) (Fus-2 protein) (Fusion 2 protein).

NEB2_HUMAN
θ value	1.81305 (rank : 298)	NC score	0.013713 (rank : 473)
Query Neighborhood Hits	587	Target Neighborhood Hits	883	Shared Neighborhood Hits	45
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NFH_HUMAN
θ value	1.81305 (rank : 299)	NC score	0.013433 (rank : 474)
Query Neighborhood Hits	587	Target Neighborhood Hits	1242	Shared Neighborhood Hits	105
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

OSTP_MOUSE
θ value	1.81305 (rank : 300)	NC score	0.016295 (rank : 440)
Query Neighborhood Hits	587	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	P10923, P19008	Gene names	Spp1, Eta-1, Op, Spp-1
Domain Architecture
Description	Osteopontin precursor (Bone sialoprotein-1) (Secreted phosphoprotein 1) (SPP-1) (Minopontin) (Early T-lymphocyte activation 1 protein) (2AR) (Calcium oxalate crystal growth inhibitor protein).

PDCD7_MOUSE
θ value	1.81305 (rank : 301)	NC score	0.027263 (rank : 338)
Query Neighborhood Hits	587	Target Neighborhood Hits	214	Shared Neighborhood Hits	28
SwissProt Accessions	Q9WTY1, Q8R5D9	Gene names	Pdcd7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18).

PPRB_MOUSE
θ value	1.81305 (rank : 302)	NC score	0.040895 (rank : 250)
Query Neighborhood Hits	587	Target Neighborhood Hits	354	Shared Neighborhood Hits	77
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

PRDM2_HUMAN
θ value	1.81305 (rank : 303)	NC score	0.011185 (rank : 512)
Query Neighborhood Hits	587	Target Neighborhood Hits	1135	Shared Neighborhood Hits	95
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

RBM12_HUMAN
θ value	1.81305 (rank : 304)	NC score	0.020197 (rank : 408)
Query Neighborhood Hits	587	Target Neighborhood Hits	298	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

RX_HUMAN
θ value	1.81305 (rank : 305)	NC score	0.006974 (rank : 577)
Query Neighborhood Hits	587	Target Neighborhood Hits	423	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y2V3	Gene names	RAX, RX
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

SALL3_HUMAN
θ value	1.81305 (rank : 306)	NC score	0.006384 (rank : 582)
Query Neighborhood Hits	587	Target Neighborhood Hits	1066	Shared Neighborhood Hits	93
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

SNIP_HUMAN
θ value	1.81305 (rank : 307)	NC score	0.032414 (rank : 305)
Query Neighborhood Hits	587	Target Neighborhood Hits	313	Shared Neighborhood Hits	55
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

SYP2L_MOUSE
θ value	1.81305 (rank : 308)	NC score	0.025757 (rank : 353)
Query Neighborhood Hits	587	Target Neighborhood Hits	289	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

TEX14_MOUSE
θ value	1.81305 (rank : 309)	NC score	0.009730 (rank : 531)
Query Neighborhood Hits	587	Target Neighborhood Hits	1333	Shared Neighborhood Hits	72
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TPTE_HUMAN
θ value	1.81305 (rank : 310)	NC score	0.120682 (rank : 60)
Query Neighborhood Hits	587	Target Neighborhood Hits	53	Shared Neighborhood Hits	25
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

TREF1_HUMAN
θ value	1.81305 (rank : 311)	NC score	0.024036 (rank : 365)
Query Neighborhood Hits	587	Target Neighborhood Hits	651	Shared Neighborhood Hits	57
SwissProt Accessions	Q96PN7, Q7Z6T2, Q7Z6T3, Q9NQ72, Q9NQ73, Q9NUN9	Gene names	TRERF1, RAPA, TREP132
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132) (Zinc finger protein rapa).

TRPM2_HUMAN
θ value	1.81305 (rank : 312)	NC score	0.015725 (rank : 449)
Query Neighborhood Hits	587	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	O94759, Q5KTC2, Q6J3P5, Q96KN6, Q96Q93	Gene names	TRPM2, EREG1, KNP3, LTRPC2, TRPC7
Domain Architecture
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7) (Estrogen- responsive element-associated gene 1 protein).

TTLL5_HUMAN
θ value	1.81305 (rank : 313)	NC score	0.012048 (rank : 497)
Query Neighborhood Hits	587	Target Neighborhood Hits	141	Shared Neighborhood Hits	23
SwissProt Accessions	Q6EMB2, Q9P1V5, Q9UPZ4	Gene names	TTLL5, KIAA0998, STAMP
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5 (SRC1 and TIF2-associated modulatory protein).

WASF2_MOUSE
θ value	1.81305 (rank : 314)	NC score	0.034608 (rank : 289)
Query Neighborhood Hits	587	Target Neighborhood Hits	315	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

ABL1_MOUSE
θ value	2.36792 (rank : 315)	NC score	0.004402 (rank : 604)
Query Neighborhood Hits	587	Target Neighborhood Hits	1178	Shared Neighborhood Hits	83
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

BCAS1_MOUSE
θ value	2.36792 (rank : 316)	NC score	0.026400 (rank : 346)
Query Neighborhood Hits	587	Target Neighborhood Hits	215	Shared Neighborhood Hits	42
SwissProt Accessions	Q80YN3, Q9CVA1	Gene names	Bcas1, Nabc1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 homolog (Novel amplified in breast cancer 1 homolog).

BCL9_MOUSE
θ value	2.36792 (rank : 317)	NC score	0.077842 (rank : 114)
Query Neighborhood Hits	587	Target Neighborhood Hits	770	Shared Neighborhood Hits	213
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CBX6_HUMAN
θ value	2.36792 (rank : 318)	NC score	0.013272 (rank : 479)
Query Neighborhood Hits	587	Target Neighborhood Hits	104	Shared Neighborhood Hits	23
SwissProt Accessions	O95503, Q96EM5	Gene names	CBX6
Domain Architecture
Description	Chromobox protein homolog 6.

CEP72_HUMAN
θ value	2.36792 (rank : 319)	NC score	0.020746 (rank : 397)
Query Neighborhood Hits	587	Target Neighborhood Hits	374	Shared Neighborhood Hits	27
SwissProt Accessions	Q9P209, Q9BV03, Q9BWM3, Q9NVR4	Gene names	CEP72, KIAA1519
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

CF047_MOUSE
θ value	2.36792 (rank : 320)	NC score	0.016093 (rank : 444)
Query Neighborhood Hits	587	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z1R4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf47 homolog.

CIC_HUMAN
θ value	2.36792 (rank : 321)	NC score	0.060994 (rank : 168)
Query Neighborhood Hits	587	Target Neighborhood Hits	992	Shared Neighborhood Hits	230
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CK021_HUMAN
θ value	2.36792 (rank : 322)	NC score	0.026178 (rank : 349)
Query Neighborhood Hits	587	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P2W6	Gene names	C11orf21
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf21.

CNOT3_HUMAN
θ value	2.36792 (rank : 323)	NC score	0.033613 (rank : 295)
Query Neighborhood Hits	587	Target Neighborhood Hits	425	Shared Neighborhood Hits	58
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CS007_HUMAN
θ value	2.36792 (rank : 324)	NC score	0.036760 (rank : 276)
Query Neighborhood Hits	587	Target Neighborhood Hits	401	Shared Neighborhood Hits	91
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

DAB2P_HUMAN
θ value	2.36792 (rank : 325)	NC score	0.010392 (rank : 521)
Query Neighborhood Hits	587	Target Neighborhood Hits	303	Shared Neighborhood Hits	29
SwissProt Accessions	Q5VWQ8, Q8TDL2, Q96SE1, Q9C0C0	Gene names	DAB2IP, AF9Q34, AIP1, KIAA1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein) (DAB2 interaction protein) (ASK-interacting protein 1).

FBX46_HUMAN
θ value	2.36792 (rank : 326)	NC score	0.019069 (rank : 416)
Query Neighborhood Hits	587	Target Neighborhood Hits	68	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PJ61	Gene names	FBXO46, FBX46, FBXO34L
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

FGD1_HUMAN
θ value	2.36792 (rank : 327)	NC score	0.012703 (rank : 490)
Query Neighborhood Hits	587	Target Neighborhood Hits	367	Shared Neighborhood Hits	60
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FIGN_MOUSE
θ value	2.36792 (rank : 328)	NC score	0.009019 (rank : 540)
Query Neighborhood Hits	587	Target Neighborhood Hits	165	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ERZ6, Q3TPB0, Q3UP57, Q6PCM0	Gene names	Fign
Domain Architecture	No domain graphic available
Description	Fidgetin.

HNRPL_MOUSE
θ value	2.36792 (rank : 329)	NC score	0.010538 (rank : 519)
Query Neighborhood Hits	587	Target Neighborhood Hits	34	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R081, O54789, Q8K0S7	Gene names	Hnrpl
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein L (hnRNP L).

HXA13_HUMAN
θ value	2.36792 (rank : 330)	NC score	0.008989 (rank : 541)
Query Neighborhood Hits	587	Target Neighborhood Hits	353	Shared Neighborhood Hits	25
SwissProt Accessions	P31271, O43371	Gene names	HOXA13, HOX1J
Domain Architecture
Description	Homeobox protein Hox-A13 (Hox-1J).

INP5E_HUMAN
θ value	2.36792 (rank : 331)	NC score	0.034242 (rank : 292)
Query Neighborhood Hits	587	Target Neighborhood Hits	201	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

JARD2_HUMAN
θ value	2.36792 (rank : 332)	NC score	0.019448 (rank : 413)
Query Neighborhood Hits	587	Target Neighborhood Hits	119	Shared Neighborhood Hits	25
SwissProt Accessions	Q92833, Q5U5L5	Gene names	JARID2, JMJ
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

JARD2_MOUSE
θ value	2.36792 (rank : 333)	NC score	0.019682 (rank : 411)
Query Neighborhood Hits	587	Target Neighborhood Hits	169	Shared Neighborhood Hits	33
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

JHD3B_MOUSE
θ value	2.36792 (rank : 334)	NC score	0.011799 (rank : 500)
Query Neighborhood Hits	587	Target Neighborhood Hits	152	Shared Neighborhood Hits	29
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

JIP2_HUMAN
θ value	2.36792 (rank : 335)	NC score	0.029208 (rank : 329)
Query Neighborhood Hits	587	Target Neighborhood Hits	288	Shared Neighborhood Hits	82
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

KIRR2_MOUSE
θ value	2.36792 (rank : 336)	NC score	0.001455 (rank : 623)
Query Neighborhood Hits	587	Target Neighborhood Hits	326	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

LAP4_HUMAN
θ value	2.36792 (rank : 337)	NC score	0.008100 (rank : 561)
Query Neighborhood Hits	587	Target Neighborhood Hits	608	Shared Neighborhood Hits	48
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

MAP4_MOUSE
θ value	2.36792 (rank : 338)	NC score	0.040111 (rank : 252)
Query Neighborhood Hits	587	Target Neighborhood Hits	409	Shared Neighborhood Hits	83
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

NOP56_HUMAN
θ value	2.36792 (rank : 339)	NC score	0.010483 (rank : 520)
Query Neighborhood Hits	587	Target Neighborhood Hits	95	Shared Neighborhood Hits	5
SwissProt Accessions	O00567, Q9NQ05	Gene names	NOL5A, NOP56
Domain Architecture
Description	Nucleolar protein Nop56 (Nucleolar protein 5A).

PHLB1_MOUSE
θ value	2.36792 (rank : 340)	NC score	0.029633 (rank : 324)
Query Neighborhood Hits	587	Target Neighborhood Hits	678	Shared Neighborhood Hits	84
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PO6F2_HUMAN
θ value	2.36792 (rank : 341)	NC score	0.021699 (rank : 388)
Query Neighborhood Hits	587	Target Neighborhood Hits	618	Shared Neighborhood Hits	81
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

RIN2_HUMAN
θ value	2.36792 (rank : 342)	NC score	0.014621 (rank : 461)
Query Neighborhood Hits	587	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WYP3, Q00425, Q5TFT8, Q9BQL3, Q9H071	Gene names	RIN2, RASSF4
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2) (Ras inhibitor JC265) (Ras association domain family 4).

SPN90_HUMAN
θ value	2.36792 (rank : 343)	NC score	0.011791 (rank : 501)
Query Neighborhood Hits	587	Target Neighborhood Hits	157	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

SYN3_HUMAN
θ value	2.36792 (rank : 344)	NC score	0.039890 (rank : 254)
Query Neighborhood Hits	587	Target Neighborhood Hits	203	Shared Neighborhood Hits	55
SwissProt Accessions	O14994	Gene names	SYN3
Domain Architecture
Description	Synapsin-3 (Synapsin III).

TBX19_MOUSE
θ value	2.36792 (rank : 345)	NC score	0.005146 (rank : 595)
Query Neighborhood Hits	587	Target Neighborhood Hits	65	Shared Neighborhood Hits	10
SwissProt Accessions	Q99ME7	Gene names	Tbx19, Tpit
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX19 (T-box protein 19) (T-box factor, pituitary).

TFE2_MOUSE
θ value	2.36792 (rank : 346)	NC score	0.009988 (rank : 526)
Query Neighborhood Hits	587	Target Neighborhood Hits	118	Shared Neighborhood Hits	16
SwissProt Accessions	P15806, Q3U153, Q8CAH9, Q8VCY4, Q922S2, Q99MB8, Q9CYJ4	Gene names	Tcf3, Alf2, Me2, Tcfe2a
Domain Architecture	No domain graphic available
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Transcription factor A1).

TRIPC_HUMAN
θ value	2.36792 (rank : 347)	NC score	0.014656 (rank : 458)
Query Neighborhood Hits	587	Target Neighborhood Hits	319	Shared Neighborhood Hits	40
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

WNK2_HUMAN
θ value	2.36792 (rank : 348)	NC score	0.013919 (rank : 468)
Query Neighborhood Hits	587	Target Neighborhood Hits	1407	Shared Neighborhood Hits	164
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ZBT45_HUMAN
θ value	2.36792 (rank : 349)	NC score	-0.001070 (rank : 640)
Query Neighborhood Hits	587	Target Neighborhood Hits	901	Shared Neighborhood Hits	56
SwissProt Accessions	Q96K62	Gene names	ZBTB45, ZNF499
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 45 (Zinc finger protein 499).

ZC3H3_MOUSE
θ value	2.36792 (rank : 350)	NC score	0.026166 (rank : 350)
Query Neighborhood Hits	587	Target Neighborhood Hits	188	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

ZEP1_MOUSE
θ value	2.36792 (rank : 351)	NC score	0.009807 (rank : 529)
Query Neighborhood Hits	587	Target Neighborhood Hits	1063	Shared Neighborhood Hits	107
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

ACE2_MOUSE
θ value	3.0926 (rank : 352)	NC score	0.011697 (rank : 503)
Query Neighborhood Hits	587	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R0I0, Q99N70, Q99N71	Gene names	Ace2
Domain Architecture	No domain graphic available
Description	Angiotensin-converting enzyme 2 precursor (EC 3.4.17.-) (ACE-related carboxypeptidase).

ANKS6_HUMAN
θ value	3.0926 (rank : 353)	NC score	0.007664 (rank : 570)
Query Neighborhood Hits	587	Target Neighborhood Hits	411	Shared Neighborhood Hits	39
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ARI1B_HUMAN
θ value	3.0926 (rank : 354)	NC score	0.057846 (rank : 185)
Query Neighborhood Hits	587	Target Neighborhood Hits	567	Shared Neighborhood Hits	147
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

BAZ2A_MOUSE
θ value	3.0926 (rank : 355)	NC score	0.041869 (rank : 245)
Query Neighborhood Hits	587	Target Neighborhood Hits	744	Shared Neighborhood Hits	151
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

CIC_MOUSE
θ value	3.0926 (rank : 356)	NC score	0.045525 (rank : 233)
Query Neighborhood Hits	587	Target Neighborhood Hits	742	Shared Neighborhood Hits	157
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CO1A1_MOUSE
θ value	3.0926 (rank : 357)	NC score	0.029526 (rank : 326)
Query Neighborhood Hits	587	Target Neighborhood Hits	457	Shared Neighborhood Hits	88
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO2A1_MOUSE
θ value	3.0926 (rank : 358)	NC score	0.025587 (rank : 356)
Query Neighborhood Hits	587	Target Neighborhood Hits	483	Shared Neighborhood Hits	95
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO4A4_HUMAN
θ value	3.0926 (rank : 359)	NC score	0.029658 (rank : 323)
Query Neighborhood Hits	587	Target Neighborhood Hits	440	Shared Neighborhood Hits	98
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

COFA1_MOUSE
θ value	3.0926 (rank : 360)	NC score	0.019609 (rank : 412)
Query Neighborhood Hits	587	Target Neighborhood Hits	305	Shared Neighborhood Hits	67
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

CREB1_HUMAN
θ value	3.0926 (rank : 361)	NC score	0.011355 (rank : 510)
Query Neighborhood Hits	587	Target Neighborhood Hits	57	Shared Neighborhood Hits	6
SwissProt Accessions	P16220, P21934, Q9UMA7	Gene names	CREB1
Domain Architecture
Description	cAMP response element-binding protein (CREB).

CREB1_MOUSE
θ value	3.0926 (rank : 362)	NC score	0.011581 (rank : 505)
Query Neighborhood Hits	587	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	Q01147	Gene names	Creb1, Creb-1
Domain Architecture
Description	cAMP response element-binding protein (CREB).

DGKK_HUMAN
θ value	3.0926 (rank : 363)	NC score	0.026608 (rank : 344)
Query Neighborhood Hits	587	Target Neighborhood Hits	378	Shared Neighborhood Hits	63
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

FA54A_HUMAN
θ value	3.0926 (rank : 364)	NC score	0.012107 (rank : 495)
Query Neighborhood Hits	587	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P444, Q5JWR7, Q6ZUE8, Q7L3U6, Q9BZ39	Gene names	FAM54A, DUFD1
Domain Architecture	No domain graphic available
Description	Protein FAM54A (DUF729 domain-containing protein 1).

FOG1_MOUSE
θ value	3.0926 (rank : 365)	NC score	0.022840 (rank : 376)
Query Neighborhood Hits	587	Target Neighborhood Hits	1237	Shared Neighborhood Hits	179
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

GCM1_MOUSE
θ value	3.0926 (rank : 366)	NC score	0.012892 (rank : 487)
Query Neighborhood Hits	587	Target Neighborhood Hits	28	Shared Neighborhood Hits	9
SwissProt Accessions	P70348, O09103	Gene names	Gcm1, Gcma
Domain Architecture
Description	Chorion-specific transcription factor GCMa (Glial cells missing homolog 1) (GCM motif protein 1) (mGCMa) (mGCM1).

GNAS1_HUMAN
θ value	3.0926 (rank : 367)	NC score	0.014863 (rank : 455)
Query Neighborhood Hits	587	Target Neighborhood Hits	278	Shared Neighborhood Hits	68
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

HSF1_HUMAN
θ value	3.0926 (rank : 368)	NC score	0.023002 (rank : 374)
Query Neighborhood Hits	587	Target Neighborhood Hits	163	Shared Neighborhood Hits	46
SwissProt Accessions	Q00613	Gene names	HSF1, HSTF1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

HXB2_MOUSE
θ value	3.0926 (rank : 369)	NC score	0.008415 (rank : 553)
Query Neighborhood Hits	587	Target Neighborhood Hits	350	Shared Neighborhood Hits	28
SwissProt Accessions	P0C1T1	Gene names	Hoxb2, Hox-2.8
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-B2 (Hox-2.8).

K0355_HUMAN
θ value	3.0926 (rank : 370)	NC score	0.021023 (rank : 394)
Query Neighborhood Hits	587	Target Neighborhood Hits	55	Shared Neighborhood Hits	11
SwissProt Accessions	O15063	Gene names	KIAA0355
Domain Architecture	No domain graphic available
Description	Protein KIAA0355.

KLF2_MOUSE
θ value	3.0926 (rank : 371)	NC score	-0.002511 (rank : 643)
Query Neighborhood Hits	587	Target Neighborhood Hits	738	Shared Neighborhood Hits	30
SwissProt Accessions	Q60843	Gene names	Klf2, Lklf
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 2 (Lung krueppel-like factor).

LIRB4_HUMAN
θ value	3.0926 (rank : 372)	NC score	0.004427 (rank : 603)
Query Neighborhood Hits	587	Target Neighborhood Hits	111	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NHJ6, O15468, O75021, Q8N1C7, Q8NHL5	Gene names	LILRB4, ILT3, LIR5
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 4 precursor (Leukocyte immunoglobulin-like receptor 5) (LIR-5) (Immunoglobulin- like transcript 3) (ILT-3) (Monocyte inhibitory receptor HM18) (CD85k antigen).

LNP_MOUSE
θ value	3.0926 (rank : 373)	NC score	0.020404 (rank : 406)
Query Neighborhood Hits	587	Target Neighborhood Hits	83	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TQ95, Q69ZC5, Q6PAQ1, Q6PEN8	Gene names	Lnp, Kiaa1715, Uln
Domain Architecture	No domain graphic available
Description	Protein lunapark (Protein ulnaless).

LRCH4_MOUSE
θ value	3.0926 (rank : 374)	NC score	0.003413 (rank : 609)
Query Neighborhood Hits	587	Target Neighborhood Hits	302	Shared Neighborhood Hits	20
SwissProt Accessions	Q921G6	Gene names	Lrch4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4.

LSD1_HUMAN
θ value	3.0926 (rank : 375)	NC score	0.023715 (rank : 369)
Query Neighborhood Hits	587	Target Neighborhood Hits	455	Shared Neighborhood Hits	93
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

NCOA1_MOUSE
θ value	3.0926 (rank : 376)	NC score	0.010655 (rank : 516)
Query Neighborhood Hits	587	Target Neighborhood Hits	196	Shared Neighborhood Hits	44
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

NIBL_MOUSE
θ value	3.0926 (rank : 377)	NC score	0.021757 (rank : 387)
Query Neighborhood Hits	587	Target Neighborhood Hits	54	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R1F1	Gene names
Domain Architecture	No domain graphic available
Description	Niban-like protein.

OTX1_MOUSE
θ value	3.0926 (rank : 378)	NC score	0.006982 (rank : 576)
Query Neighborhood Hits	587	Target Neighborhood Hits	372	Shared Neighborhood Hits	25
SwissProt Accessions	P80205	Gene names	Otx1, Otx-1
Domain Architecture
Description	Homeobox protein OTX1.

PKNX2_MOUSE
θ value	3.0926 (rank : 379)	NC score	0.014541 (rank : 462)
Query Neighborhood Hits	587	Target Neighborhood Hits	197	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BG99, Q8R4B0	Gene names	Pknox2, Prep2
Domain Architecture	No domain graphic available
Description	Homeobox protein PKNOX2 (PBX/knotted homeobox 2) (Homeobox protein PREP-2).

PTN23_MOUSE
θ value	3.0926 (rank : 380)	NC score	0.029603 (rank : 325)
Query Neighborhood Hits	587	Target Neighborhood Hits	726	Shared Neighborhood Hits	114
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

ROBO4_MOUSE
θ value	3.0926 (rank : 381)	NC score	0.003626 (rank : 608)
Query Neighborhood Hits	587	Target Neighborhood Hits	358	Shared Neighborhood Hits	18
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

SHC1_HUMAN
θ value	3.0926 (rank : 382)	NC score	0.013336 (rank : 477)
Query Neighborhood Hits	587	Target Neighborhood Hits	170	Shared Neighborhood Hits	17
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SMRC1_MOUSE
θ value	3.0926 (rank : 383)	NC score	0.020665 (rank : 400)
Query Neighborhood Hits	587	Target Neighborhood Hits	459	Shared Neighborhood Hits	55
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

SRCA_HUMAN
θ value	3.0926 (rank : 384)	NC score	0.021427 (rank : 391)
Query Neighborhood Hits	587	Target Neighborhood Hits	380	Shared Neighborhood Hits	56
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

SREC2_MOUSE
θ value	3.0926 (rank : 385)	NC score	0.016845 (rank : 436)
Query Neighborhood Hits	587	Target Neighborhood Hits	605	Shared Neighborhood Hits	51
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

STAG3_MOUSE
θ value	3.0926 (rank : 386)	NC score	0.006228 (rank : 585)
Query Neighborhood Hits	587	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	O70576	Gene names	Stag3
Domain Architecture
Description	Cohesin subunit SA-3 (Stromal antigen 3) (Stromalin 3) (SCC3 homolog 3).

ZDHC5_HUMAN
θ value	3.0926 (rank : 387)	NC score	0.016780 (rank : 438)
Query Neighborhood Hits	587	Target Neighborhood Hits	106	Shared Neighborhood Hits	16
SwissProt Accessions	Q9C0B5, Q6ZMF0, Q8TAK8, Q9H923, Q9UFI7	Gene names	ZDHHC5, KIAA1748, ZNF375
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC5 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 5) (DHHC-5) (Zinc finger protein 375).

3BP1_MOUSE
θ value	4.03905 (rank : 388)	NC score	0.023720 (rank : 368)
Query Neighborhood Hits	587	Target Neighborhood Hits	238	Shared Neighborhood Hits	42
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

ASPP1_MOUSE
θ value	4.03905 (rank : 389)	NC score	0.034505 (rank : 290)
Query Neighborhood Hits	587	Target Neighborhood Hits	1244	Shared Neighborhood Hits	181
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ATX7_MOUSE
θ value	4.03905 (rank : 390)	NC score	0.050557 (rank : 218)
Query Neighborhood Hits	587	Target Neighborhood Hits	328	Shared Neighborhood Hits	117
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

BAI1_MOUSE
θ value	4.03905 (rank : 391)	NC score	0.003783 (rank : 607)
Query Neighborhood Hits	587	Target Neighborhood Hits	340	Shared Neighborhood Hits	30
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

CO002_HUMAN
θ value	4.03905 (rank : 392)	NC score	0.048316 (rank : 227)
Query Neighborhood Hits	587	Target Neighborhood Hits	387	Shared Neighborhood Hits	101
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

CO039_HUMAN
θ value	4.03905 (rank : 393)	NC score	0.039074 (rank : 259)
Query Neighborhood Hits	587	Target Neighborhood Hits	264	Shared Neighborhood Hits	86
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

CY24A_HUMAN
θ value	4.03905 (rank : 394)	NC score	0.013765 (rank : 472)
Query Neighborhood Hits	587	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	P13498, Q14090, Q9BR72	Gene names	CYBA
Domain Architecture
Description	Cytochrome b-245 light chain (p22 phagocyte B-cytochrome) (Neutrophil cytochrome b 22 kDa polypeptide) (p22-phox) (p22phox) (Cytochrome b(558) alpha chain) (Cytochrome b558 subunit alpha) (Superoxide- generating NADPH oxidase light chain subunit).

DDFL1_MOUSE
θ value	4.03905 (rank : 395)	NC score	0.009159 (rank : 537)
Query Neighborhood Hits	587	Target Neighborhood Hits	324	Shared Neighborhood Hits	21
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

DTNB_MOUSE
θ value	4.03905 (rank : 396)	NC score	0.006612 (rank : 581)
Query Neighborhood Hits	587	Target Neighborhood Hits	263	Shared Neighborhood Hits	21
SwissProt Accessions	O70585, O70563, Q9CTZ1	Gene names	Dtnb
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B) (MDTN-B).

EFS_HUMAN
θ value	4.03905 (rank : 397)	NC score	0.026576 (rank : 345)
Query Neighborhood Hits	587	Target Neighborhood Hits	348	Shared Neighborhood Hits	74
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

F120C_MOUSE
θ value	4.03905 (rank : 398)	NC score	0.018275 (rank : 427)
Query Neighborhood Hits	587	Target Neighborhood Hits	98	Shared Neighborhood Hits	35
SwissProt Accessions	Q8C3F2	Gene names	Fam120c, ORF34
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120C.

FGD1_MOUSE
θ value	4.03905 (rank : 399)	NC score	0.013793 (rank : 471)
Query Neighborhood Hits	587	Target Neighborhood Hits	387	Shared Neighborhood Hits	79
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FMNL_HUMAN
θ value	4.03905 (rank : 400)	NC score	0.027462 (rank : 337)
Query Neighborhood Hits	587	Target Neighborhood Hits	529	Shared Neighborhood Hits	83
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

FXR2_HUMAN
θ value	4.03905 (rank : 401)	NC score	0.006111 (rank : 587)
Query Neighborhood Hits	587	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	P51116, Q8WUM2	Gene names	FXR2
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

GFC1_HUMAN
θ value	4.03905 (rank : 402)	NC score	0.017385 (rank : 432)
Query Neighborhood Hits	587	Target Neighborhood Hits	95	Shared Neighborhood Hits	20
SwissProt Accessions	P63117	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)1_Xq21.33 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein].

GGA3_MOUSE
θ value	4.03905 (rank : 403)	NC score	0.011755 (rank : 502)
Query Neighborhood Hits	587	Target Neighborhood Hits	148	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

HCN2_HUMAN
θ value	4.03905 (rank : 404)	NC score	0.033117 (rank : 299)
Query Neighborhood Hits	587	Target Neighborhood Hits	369	Shared Neighborhood Hits	95
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

K0174_MOUSE
θ value	4.03905 (rank : 405)	NC score	0.013190 (rank : 481)
Query Neighborhood Hits	587	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	Q9CX00, Q80U68	Gene names	Kiaa0174
Domain Architecture	No domain graphic available
Description	Protein KIAA0174.

KCNA2_HUMAN
θ value	4.03905 (rank : 406)	NC score	0.087689 (rank : 87)
Query Neighborhood Hits	587	Target Neighborhood Hits	101	Shared Neighborhood Hits	36
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNA2_MOUSE
θ value	4.03905 (rank : 407)	NC score	0.088951 (rank : 86)
Query Neighborhood Hits	587	Target Neighborhood Hits	102	Shared Neighborhood Hits	37
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KIFC2_HUMAN
θ value	4.03905 (rank : 408)	NC score	0.002242 (rank : 621)
Query Neighborhood Hits	587	Target Neighborhood Hits	237	Shared Neighborhood Hits	19
SwissProt Accessions	Q96AC6	Gene names	KIFC2
Domain Architecture
Description	Kinesin-like protein KIFC2.

KS6A3_HUMAN
θ value	4.03905 (rank : 409)	NC score	-0.000853 (rank : 639)
Query Neighborhood Hits	587	Target Neighborhood Hits	859	Shared Neighborhood Hits	28
SwissProt Accessions	P51812, Q4VAP3, Q59H26, Q5JPK8, Q7Z3Z7	Gene names	RPS6KA3, ISPK1, RSK2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1) (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B).

KS6A3_MOUSE
θ value	4.03905 (rank : 410)	NC score	-0.000845 (rank : 638)
Query Neighborhood Hits	587	Target Neighborhood Hits	860	Shared Neighborhood Hits	28
SwissProt Accessions	P18654, Q03140, Q8K3J8	Gene names	Rps6ka3, Rps6ka-rs1, Rsk2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1) (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B).

LNP_HUMAN
θ value	4.03905 (rank : 411)	NC score	0.017998 (rank : 430)
Query Neighborhood Hits	587	Target Neighborhood Hits	62	Shared Neighborhood Hits	11
SwissProt Accessions	Q9C0E8, Q2M2V8, Q2YD99, Q658W8, Q8N5V9, Q96MS5	Gene names	LNP, KIAA1715
Domain Architecture	No domain graphic available
Description	Protein lunapark.

M4K4_MOUSE
θ value	4.03905 (rank : 412)	NC score	0.000203 (rank : 634)
Query Neighborhood Hits	587	Target Neighborhood Hits	1560	Shared Neighborhood Hits	68
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MAGE1_HUMAN
θ value	4.03905 (rank : 413)	NC score	0.090566 (rank : 81)
Query Neighborhood Hits	587	Target Neighborhood Hits	1389	Shared Neighborhood Hits	318
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MAK_MOUSE
θ value	4.03905 (rank : 414)	NC score	-0.000130 (rank : 635)
Query Neighborhood Hits	587	Target Neighborhood Hits	873	Shared Neighborhood Hits	36
SwissProt Accessions	Q04859	Gene names	Mak, Rck
Domain Architecture
Description	Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male germ cell- associated kinase) (Protein kinase RCK).

MLL3_HUMAN
θ value	4.03905 (rank : 415)	NC score	0.086123 (rank : 92)
Query Neighborhood Hits	587	Target Neighborhood Hits	1644	Shared Neighborhood Hits	280
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PACS1_HUMAN
θ value	4.03905 (rank : 416)	NC score	0.018956 (rank : 417)
Query Neighborhood Hits	587	Target Neighborhood Hits	82	Shared Neighborhood Hits	18
SwissProt Accessions	Q6VY07, Q6PJY6, Q6PKB6, Q7Z590, Q7Z5W4, Q8N8K6, Q96MW0, Q9NW92, Q9ULP5	Gene names	PACS1, KIAA1175
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

PACS1_MOUSE
θ value	4.03905 (rank : 417)	NC score	0.015949 (rank : 447)
Query Neighborhood Hits	587	Target Neighborhood Hits	87	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K212, Q6P5H8	Gene names	Pacs1
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

PDCD7_HUMAN
θ value	4.03905 (rank : 418)	NC score	0.025756 (rank : 354)
Query Neighborhood Hits	587	Target Neighborhood Hits	255	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

PI5PA_MOUSE
θ value	4.03905 (rank : 419)	NC score	0.035935 (rank : 281)
Query Neighborhood Hits	587	Target Neighborhood Hits	331	Shared Neighborhood Hits	84
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PKHA4_HUMAN
θ value	4.03905 (rank : 420)	NC score	0.020147 (rank : 409)
Query Neighborhood Hits	587	Target Neighborhood Hits	283	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKNX2_HUMAN
θ value	4.03905 (rank : 421)	NC score	0.009870 (rank : 528)
Query Neighborhood Hits	587	Target Neighborhood Hits	133	Shared Neighborhood Hits	17
SwissProt Accessions	Q96KN3, Q63HL6, Q86XD1	Gene names	PKNOX2, PREP2
Domain Architecture
Description	Homeobox protein PKNOX2 (PBX/knotted homeobox 2) (Homeobox protein PREP-2).

POMT1_MOUSE
θ value	4.03905 (rank : 422)	NC score	0.007778 (rank : 567)
Query Neighborhood Hits	587	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R2R1, Q3UYD8, Q64J18, Q8BPJ6, Q8BPU1, Q8R474	Gene names	Pomt1
Domain Architecture
Description	Protein O-mannosyl-transferase 1 (EC 2.4.1.109) (Dolichyl-phosphate- mannose--protein mannosyltransferase 1).

PRB3_HUMAN
θ value	4.03905 (rank : 423)	NC score	0.055147 (rank : 198)
Query Neighborhood Hits	587	Target Neighborhood Hits	318	Shared Neighborhood Hits	77
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PSD4_HUMAN
θ value	4.03905 (rank : 424)	NC score	0.025429 (rank : 357)
Query Neighborhood Hits	587	Target Neighborhood Hits	178	Shared Neighborhood Hits	44
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

R3HD1_HUMAN
θ value	4.03905 (rank : 425)	NC score	0.022674 (rank : 379)
Query Neighborhood Hits	587	Target Neighborhood Hits	203	Shared Neighborhood Hits	39
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

RP3A_HUMAN
θ value	4.03905 (rank : 426)	NC score	0.016446 (rank : 439)
Query Neighborhood Hits	587	Target Neighborhood Hits	305	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SF3B4_HUMAN
θ value	4.03905 (rank : 427)	NC score	0.029840 (rank : 319)
Query Neighborhood Hits	587	Target Neighborhood Hits	445	Shared Neighborhood Hits	66
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

SOS2_HUMAN
θ value	4.03905 (rank : 428)	NC score	0.009712 (rank : 533)
Query Neighborhood Hits	587	Target Neighborhood Hits	193	Shared Neighborhood Hits	27
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

SOX9_HUMAN
θ value	4.03905 (rank : 429)	NC score	0.006309 (rank : 583)
Query Neighborhood Hits	587	Target Neighborhood Hits	210	Shared Neighborhood Hits	33
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.

TMEM8_MOUSE
θ value	4.03905 (rank : 430)	NC score	0.009789 (rank : 530)
Query Neighborhood Hits	587	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ESN3, Q99JS5	Gene names	Tmem8
Domain Architecture	No domain graphic available
Description	Transmembrane protein 8 precursor (M83 protein).

TTP_HUMAN
θ value	4.03905 (rank : 431)	NC score	0.013835 (rank : 470)
Query Neighborhood Hits	587	Target Neighborhood Hits	86	Shared Neighborhood Hits	13
SwissProt Accessions	P26651	Gene names	ZFP36, G0S24, TIS11A, TTP
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (G0/G1 switch regulatory protein 24).

WASL_HUMAN
θ value	4.03905 (rank : 432)	NC score	0.037390 (rank : 268)
Query Neighborhood Hits	587	Target Neighborhood Hits	312	Shared Neighborhood Hits	74
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

ZCPW1_MOUSE
θ value	4.03905 (rank : 433)	NC score	0.023319 (rank : 370)
Query Neighborhood Hits	587	Target Neighborhood Hits	307	Shared Neighborhood Hits	48
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

ABI2_MOUSE
θ value	5.27518 (rank : 434)	NC score	0.012208 (rank : 494)
Query Neighborhood Hits	587	Target Neighborhood Hits	266	Shared Neighborhood Hits	22
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

ACD_HUMAN
θ value	5.27518 (rank : 435)	NC score	0.022860 (rank : 375)
Query Neighborhood Hits	587	Target Neighborhood Hits	143	Shared Neighborhood Hits	35
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

ASTN_HUMAN
θ value	5.27518 (rank : 436)	NC score	0.014094 (rank : 465)
Query Neighborhood Hits	587	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

BACH_HUMAN
θ value	5.27518 (rank : 437)	NC score	0.011466 (rank : 509)
Query Neighborhood Hits	587	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	O00154, O43703, Q5JYL4, Q9UJM9, Q9Y539, Q9Y540	Gene names	ACOT7, BACH
Domain Architecture
Description	Cytosolic acyl coenzyme A thioester hydrolase (EC 3.1.2.2) (Long chain acyl-CoA thioester hydrolase) (CTE-II) (CTE-IIa) (Brain acyl-CoA hydrolase) (Acyl-CoA thioesterase 7).

BACH_MOUSE
θ value	5.27518 (rank : 438)	NC score	0.011499 (rank : 507)
Query Neighborhood Hits	587	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q91V12, Q59HQ2	Gene names	Acot7, Bach
Domain Architecture
Description	Cytosolic acyl coenzyme A thioester hydrolase (EC 3.1.2.2) (Long chain acyl-CoA thioester hydrolase) (CTE-II) (CTE-IIa) (Brain acyl-CoA hydrolase) (Acyl-CoA thioesterase 7).

BARD1_MOUSE
θ value	5.27518 (rank : 439)	NC score	0.005081 (rank : 596)
Query Neighborhood Hits	587	Target Neighborhood Hits	411	Shared Neighborhood Hits	23
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

CBP_HUMAN
θ value	5.27518 (rank : 440)	NC score	0.060607 (rank : 169)
Query Neighborhood Hits	587	Target Neighborhood Hits	941	Shared Neighborhood Hits	195
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CCD95_HUMAN
θ value	5.27518 (rank : 441)	NC score	0.018181 (rank : 428)
Query Neighborhood Hits	587	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NBZ0	Gene names	CCDC95
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 95.

CHSTC_HUMAN
θ value	5.27518 (rank : 442)	NC score	0.004628 (rank : 600)
Query Neighborhood Hits	587	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NRB3, Q9NXY7	Gene names	CHST12
Domain Architecture	No domain graphic available
Description	Carbohydrate sulfotransferase 12 (EC 2.8.2.5) (Chondroitin 4-O- sulfotransferase 2) (Chondroitin 4-sulfotransferase 2) (C4ST2) (C4ST- 2) (Sulfotransferase Hlo).

CO7A1_HUMAN
θ value	5.27518 (rank : 443)	NC score	0.022784 (rank : 377)
Query Neighborhood Hits	587	Target Neighborhood Hits	807	Shared Neighborhood Hits	121
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CSTFT_MOUSE
θ value	5.27518 (rank : 444)	NC score	0.018081 (rank : 429)
Query Neighborhood Hits	587	Target Neighborhood Hits	356	Shared Neighborhood Hits	56
SwissProt Accessions	Q8C7E9, Q6A016, Q8BHH7, Q8C3W7, Q8R2Y1, Q9EPU3	Gene names	Cstf2t, Kiaa0689
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit, tau variant (CSTF 64 kDa subunit, tau variant) (CF-1 64 kDa subunit, tau variant) (TauCstF-64).

DYR1B_HUMAN
θ value	5.27518 (rank : 445)	NC score	0.000565 (rank : 631)
Query Neighborhood Hits	587	Target Neighborhood Hits	831	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y463, O75258, O75788, O75789	Gene names	DYRK1B, MIRK
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Mirk protein kinase) (Minibrain-related kinase).

EMID2_HUMAN
θ value	5.27518 (rank : 446)	NC score	0.018568 (rank : 422)
Query Neighborhood Hits	587	Target Neighborhood Hits	226	Shared Neighborhood Hits	51
SwissProt Accessions	Q96A83	Gene names	EMID2, COL26A1, EMU2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

F120C_HUMAN
θ value	5.27518 (rank : 447)	NC score	0.014831 (rank : 456)
Query Neighborhood Hits	587	Target Neighborhood Hits	91	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NX05	Gene names	FAM120C, CXorf17
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120C (Tumor antigen BJ-HCC-21).

FMN1B_MOUSE
θ value	5.27518 (rank : 448)	NC score	0.029399 (rank : 328)
Query Neighborhood Hits	587	Target Neighborhood Hits	447	Shared Neighborhood Hits	78
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

FOXC2_HUMAN
θ value	5.27518 (rank : 449)	NC score	0.007535 (rank : 573)
Query Neighborhood Hits	587	Target Neighborhood Hits	236	Shared Neighborhood Hits	49
SwissProt Accessions	Q99958	Gene names	FOXC2, FKHL14, MFH1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

GLI1_HUMAN
θ value	5.27518 (rank : 450)	NC score	-0.001713 (rank : 642)
Query Neighborhood Hits	587	Target Neighborhood Hits	828	Shared Neighborhood Hits	54
SwissProt Accessions	P08151, Q8TDN9	Gene names	GLI1, GLI
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI).

GNAS1_MOUSE
θ value	5.27518 (rank : 451)	NC score	0.036826 (rank : 275)
Query Neighborhood Hits	587	Target Neighborhood Hits	651	Shared Neighborhood Hits	176
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

GRIN1_MOUSE
θ value	5.27518 (rank : 452)	NC score	0.043361 (rank : 240)
Query Neighborhood Hits	587	Target Neighborhood Hits	337	Shared Neighborhood Hits	92
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

HD_HUMAN
θ value	5.27518 (rank : 453)	NC score	0.010653 (rank : 517)
Query Neighborhood Hits	587	Target Neighborhood Hits	165	Shared Neighborhood Hits	22
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

HXA13_MOUSE
θ value	5.27518 (rank : 454)	NC score	0.007794 (rank : 566)
Query Neighborhood Hits	587	Target Neighborhood Hits	351	Shared Neighborhood Hits	24
SwissProt Accessions	Q62424	Gene names	Hoxa13, Hox-1.10
Domain Architecture
Description	Homeobox protein Hox-A13 (Hox-1.10).

I17RD_HUMAN
θ value	5.27518 (rank : 455)	NC score	0.007766 (rank : 568)
Query Neighborhood Hits	587	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NFM7, Q58EZ7, Q6RVF4, Q6UWI5, Q8N113, Q8NFS0, Q9UFA0	Gene names	IL17RD, IL17RLM, SEF
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor D precursor (IL-17 receptor D) (IL-17RD) (Interleukin-17D receptor) (IL-17D receptor) (IL17Rhom) (Interleukin- 17 receptor-like protein) (Sef homolog) (hSef).

IL29_HUMAN
θ value	5.27518 (rank : 456)	NC score	0.008665 (rank : 547)
Query Neighborhood Hits	587	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IU54	Gene names	IL29, IFNL1, ZCYTO21
Domain Architecture	No domain graphic available
Description	Interleukin-29 precursor (IL-29) (Interferon lambda-1) (IFN-lambda-1) (Cytokine ZCYTO21).

ITPR1_HUMAN
θ value	5.27518 (rank : 457)	NC score	0.008949 (rank : 542)
Query Neighborhood Hits	587	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q14643, Q14660, Q99897	Gene names	ITPR1, INSP3R1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (IP3R).

ITPR1_MOUSE
θ value	5.27518 (rank : 458)	NC score	0.008903 (rank : 543)
Query Neighborhood Hits	587	Target Neighborhood Hits	99	Shared Neighborhood Hits	10
SwissProt Accessions	P11881, P20943, Q99LG5	Gene names	Itpr1, Insp3r, Pcd6, Pcp1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (Inositol 1,4,5-trisphosphate-binding protein P400) (Purkinje cell protein 1) (Protein PCD-6).

KCC2B_HUMAN
θ value	5.27518 (rank : 459)	NC score	0.000526 (rank : 633)
Query Neighborhood Hits	587	Target Neighborhood Hits	866	Shared Neighborhood Hits	37
SwissProt Accessions	Q13554, O95437, O95438, O95599, Q9UGH7, Q9UGH8, Q9UGH9, Q9UNX0, Q9UNX7, Q9UP00, Q9Y5N4, Q9Y6F4	Gene names	CAMK2B, CAM2, CAMKB
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II beta chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II subunit beta) (CaMK-II subunit beta).

KCNQ1_MOUSE
θ value	5.27518 (rank : 460)	NC score	0.085180 (rank : 94)
Query Neighborhood Hits	587	Target Neighborhood Hits	175	Shared Neighborhood Hits	65
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

LEUK_HUMAN
θ value	5.27518 (rank : 461)	NC score	0.039083 (rank : 258)
Query Neighborhood Hits	587	Target Neighborhood Hits	213	Shared Neighborhood Hits	50
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

M3K6_HUMAN
θ value	5.27518 (rank : 462)	NC score	0.001284 (rank : 627)
Query Neighborhood Hits	587	Target Neighborhood Hits	889	Shared Neighborhood Hits	38
SwissProt Accessions	O95382	Gene names	MAP3K6, MAPKKK6
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25).

MARK4_MOUSE
θ value	5.27518 (rank : 463)	NC score	0.000633 (rank : 630)
Query Neighborhood Hits	587	Target Neighborhood Hits	898	Shared Neighborhood Hits	41
SwissProt Accessions	Q8CIP4, Q80T81	Gene names	Mark4, Kiaa1860
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1).

MEGF8_HUMAN
θ value	5.27518 (rank : 464)	NC score	0.006167 (rank : 586)
Query Neighborhood Hits	587	Target Neighborhood Hits	528	Shared Neighborhood Hits	20
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MTF1_MOUSE
θ value	5.27518 (rank : 465)	NC score	-0.003326 (rank : 648)
Query Neighborhood Hits	587	Target Neighborhood Hits	785	Shared Neighborhood Hits	38
SwissProt Accessions	Q07243	Gene names	Mtf1, Mtf-1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

MUC13_MOUSE
θ value	5.27518 (rank : 466)	NC score	0.026082 (rank : 351)
Query Neighborhood Hits	587	Target Neighborhood Hits	447	Shared Neighborhood Hits	54
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

MUC2_HUMAN
θ value	5.27518 (rank : 467)	NC score	0.025171 (rank : 359)
Query Neighborhood Hits	587	Target Neighborhood Hits	906	Shared Neighborhood Hits	97
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MYCB2_HUMAN
θ value	5.27518 (rank : 468)	NC score	0.015344 (rank : 452)
Query Neighborhood Hits	587	Target Neighborhood Hits	390	Shared Neighborhood Hits	42
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

MYCL1_MOUSE
θ value	5.27518 (rank : 469)	NC score	0.006250 (rank : 584)
Query Neighborhood Hits	587	Target Neighborhood Hits	123	Shared Neighborhood Hits	9
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

P85B_HUMAN
θ value	5.27518 (rank : 470)	NC score	0.003047 (rank : 614)
Query Neighborhood Hits	587	Target Neighborhood Hits	543	Shared Neighborhood Hits	34
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PRGC2_MOUSE
θ value	5.27518 (rank : 471)	NC score	0.024861 (rank : 362)
Query Neighborhood Hits	587	Target Neighborhood Hits	225	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

PRRT3_HUMAN
θ value	5.27518 (rank : 472)	NC score	0.129503 (rank : 56)
Query Neighborhood Hits	587	Target Neighborhood Hits	998	Shared Neighborhood Hits	296
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RAVR2_MOUSE
θ value	5.27518 (rank : 473)	NC score	0.008713 (rank : 546)
Query Neighborhood Hits	587	Target Neighborhood Hits	137	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TPD6	Gene names	Raver2, Kiaa1579
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 2 (Protein raver-2).

SNPC4_MOUSE
θ value	5.27518 (rank : 474)	NC score	0.020675 (rank : 399)
Query Neighborhood Hits	587	Target Neighborhood Hits	237	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

SOS1_MOUSE
θ value	5.27518 (rank : 475)	NC score	0.016186 (rank : 443)
Query Neighborhood Hits	587	Target Neighborhood Hits	281	Shared Neighborhood Hits	43
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

SP8_HUMAN
θ value	5.27518 (rank : 476)	NC score	-0.003316 (rank : 647)
Query Neighborhood Hits	587	Target Neighborhood Hits	714	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IXZ3, Q7Z616, Q96MJ1	Gene names	SP8
Domain Architecture	No domain graphic available
Description	Transcription factor Sp8 (Specificity protein 8).

SPEG_HUMAN
θ value	5.27518 (rank : 477)	NC score	0.011489 (rank : 508)
Query Neighborhood Hits	587	Target Neighborhood Hits	1762	Shared Neighborhood Hits	184
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SYN3_MOUSE
θ value	5.27518 (rank : 478)	NC score	0.032978 (rank : 301)
Query Neighborhood Hits	587	Target Neighborhood Hits	200	Shared Neighborhood Hits	50
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

SYP2L_HUMAN
θ value	5.27518 (rank : 479)	NC score	0.032618 (rank : 303)
Query Neighborhood Hits	587	Target Neighborhood Hits	400	Shared Neighborhood Hits	93
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

TAF3_MOUSE
θ value	5.27518 (rank : 480)	NC score	0.018487 (rank : 424)
Query Neighborhood Hits	587	Target Neighborhood Hits	463	Shared Neighborhood Hits	42
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TB182_HUMAN
θ value	5.27518 (rank : 481)	NC score	0.036037 (rank : 280)
Query Neighborhood Hits	587	Target Neighborhood Hits	414	Shared Neighborhood Hits	80
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

VASP_HUMAN
θ value	5.27518 (rank : 482)	NC score	0.029671 (rank : 322)
Query Neighborhood Hits	587	Target Neighborhood Hits	201	Shared Neighborhood Hits	50
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

VASP_MOUSE
θ value	5.27518 (rank : 483)	NC score	0.027559 (rank : 334)
Query Neighborhood Hits	587	Target Neighborhood Hits	195	Shared Neighborhood Hits	42
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

WASF4_HUMAN
θ value	5.27518 (rank : 484)	NC score	0.030048 (rank : 317)
Query Neighborhood Hits	587	Target Neighborhood Hits	282	Shared Neighborhood Hits	71
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

WASL_MOUSE
θ value	5.27518 (rank : 485)	NC score	0.036904 (rank : 274)
Query Neighborhood Hits	587	Target Neighborhood Hits	339	Shared Neighborhood Hits	72
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASP_MOUSE
θ value	5.27518 (rank : 486)	NC score	0.030069 (rank : 316)
Query Neighborhood Hits	587	Target Neighborhood Hits	223	Shared Neighborhood Hits	60
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

WBS14_HUMAN
θ value	5.27518 (rank : 487)	NC score	0.024782 (rank : 363)
Query Neighborhood Hits	587	Target Neighborhood Hits	273	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

ZIM10_HUMAN
θ value	5.27518 (rank : 488)	NC score	0.054045 (rank : 205)
Query Neighborhood Hits	587	Target Neighborhood Hits	577	Shared Neighborhood Hits	171
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ACINU_HUMAN
θ value	6.88961 (rank : 489)	NC score	0.031050 (rank : 309)
Query Neighborhood Hits	587	Target Neighborhood Hits	828	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ANK2_HUMAN
θ value	6.88961 (rank : 490)	NC score	0.038572 (rank : 263)
Query Neighborhood Hits	587	Target Neighborhood Hits	1615	Shared Neighborhood Hits	252
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANR40_MOUSE
θ value	6.88961 (rank : 491)	NC score	0.005792 (rank : 588)
Query Neighborhood Hits	587	Target Neighborhood Hits	228	Shared Neighborhood Hits	19
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

APS_HUMAN
θ value	6.88961 (rank : 492)	NC score	0.007149 (rank : 574)
Query Neighborhood Hits	587	Target Neighborhood Hits	162	Shared Neighborhood Hits	15
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

ATX2_MOUSE
θ value	6.88961 (rank : 493)	NC score	0.046262 (rank : 231)
Query Neighborhood Hits	587	Target Neighborhood Hits	445	Shared Neighborhood Hits	113
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

CI079_HUMAN
θ value	6.88961 (rank : 494)	NC score	0.041846 (rank : 246)
Query Neighborhood Hits	587	Target Neighborhood Hits	288	Shared Neighborhood Hits	84
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

CJ078_MOUSE
θ value	6.88961 (rank : 495)	NC score	0.049291 (rank : 225)
Query Neighborhood Hits	587	Target Neighborhood Hits	559	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CO4A5_HUMAN
θ value	6.88961 (rank : 496)	NC score	0.022760 (rank : 378)
Query Neighborhood Hits	587	Target Neighborhood Hits	383	Shared Neighborhood Hits	81
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

COFA1_HUMAN
θ value	6.88961 (rank : 497)	NC score	0.020852 (rank : 396)
Query Neighborhood Hits	587	Target Neighborhood Hits	292	Shared Neighborhood Hits	64
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

DREB_MOUSE
θ value	6.88961 (rank : 498)	NC score	0.009141 (rank : 538)
Query Neighborhood Hits	587	Target Neighborhood Hits	446	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

EP400_HUMAN
θ value	6.88961 (rank : 499)	NC score	0.022352 (rank : 382)
Query Neighborhood Hits	587	Target Neighborhood Hits	556	Shared Neighborhood Hits	93
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

F100A_HUMAN
θ value	6.88961 (rank : 500)	NC score	0.010018 (rank : 525)
Query Neighborhood Hits	587	Target Neighborhood Hits	39	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TB05, Q71MF6	Gene names	FAM100A
Domain Architecture	No domain graphic available
Description	Protein FAM100A.

FAK2_HUMAN
θ value	6.88961 (rank : 501)	NC score	0.001381 (rank : 626)
Query Neighborhood Hits	587	Target Neighborhood Hits	847	Shared Neighborhood Hits	28
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

FAK2_MOUSE
θ value	6.88961 (rank : 502)	NC score	0.001397 (rank : 625)
Query Neighborhood Hits	587	Target Neighborhood Hits	851	Shared Neighborhood Hits	29
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

GA2L3_HUMAN
θ value	6.88961 (rank : 503)	NC score	0.017271 (rank : 434)
Query Neighborhood Hits	587	Target Neighborhood Hits	189	Shared Neighborhood Hits	42
SwissProt Accessions	Q86XJ1	Gene names	GAS2L3
Domain Architecture	No domain graphic available
Description	GAS2-like protein 3 (Growth arrest-specific 2-like 3).

HES7_MOUSE
θ value	6.88961 (rank : 504)	NC score	0.010776 (rank : 515)
Query Neighborhood Hits	587	Target Neighborhood Hits	72	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BKT2, Q99JA6	Gene names	Hes7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

IF4G1_HUMAN
θ value	6.88961 (rank : 505)	NC score	0.017354 (rank : 433)
Query Neighborhood Hits	587	Target Neighborhood Hits	347	Shared Neighborhood Hits	69
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

INVS_MOUSE
θ value	6.88961 (rank : 506)	NC score	0.021295 (rank : 392)
Query Neighborhood Hits	587	Target Neighborhood Hits	609	Shared Neighborhood Hits	121
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

JPH2_MOUSE
θ value	6.88961 (rank : 507)	NC score	0.015491 (rank : 450)
Query Neighborhood Hits	587	Target Neighborhood Hits	279	Shared Neighborhood Hits	62
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

LAP4_MOUSE
θ value	6.88961 (rank : 508)	NC score	0.004604 (rank : 601)
Query Neighborhood Hits	587	Target Neighborhood Hits	590	Shared Neighborhood Hits	47
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

LHX3_MOUSE
θ value	6.88961 (rank : 509)	NC score	0.002581 (rank : 619)
Query Neighborhood Hits	587	Target Neighborhood Hits	451	Shared Neighborhood Hits	26
SwissProt Accessions	P50481, Q61800, Q61801	Gene names	Lhx3, Lim-3, Lim3, Plim
Domain Architecture
Description	LIM/homeobox protein Lhx3 (Homeobox protein LIM-3) (Homeobox protein P-LIM) (LIM homeobox protein 3).

LPP_MOUSE
θ value	6.88961 (rank : 510)	NC score	0.012367 (rank : 492)
Query Neighborhood Hits	587	Target Neighborhood Hits	247	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BFW7, Q5U407, Q8BHI1, Q8BKI0, Q8BKN2, Q8BLF4, Q8BLG3, Q8C101	Gene names	Lpp
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner homolog.

MAP1A_HUMAN
θ value	6.88961 (rank : 511)	NC score	0.043686 (rank : 239)
Query Neighborhood Hits	587	Target Neighborhood Hits	1626	Shared Neighborhood Hits	215
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

PAR4_HUMAN
θ value	6.88961 (rank : 512)	NC score	-0.007744 (rank : 652)
Query Neighborhood Hits	587	Target Neighborhood Hits	821	Shared Neighborhood Hits	3
SwissProt Accessions	Q96RI0, O76067, Q6DK42	Gene names	F2RL3, PAR4
Domain Architecture
Description	Proteinase-activated receptor 4 precursor (PAR-4) (Thrombin receptor- like 3) (Coagulation factor II receptor-like 3).

PHAR3_HUMAN
θ value	6.88961 (rank : 513)	NC score	0.010315 (rank : 523)
Query Neighborhood Hits	587	Target Neighborhood Hits	169	Shared Neighborhood Hits	20
SwissProt Accessions	Q96KR7, Q707P6, Q9H4T4	Gene names	PHACTR3, C20orf101, SCAPIN1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

PHC3_HUMAN
θ value	6.88961 (rank : 514)	NC score	0.019201 (rank : 414)
Query Neighborhood Hits	587	Target Neighborhood Hits	218	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NDX5, Q5HYF0, Q6NSG2, Q8NFT7, Q8NFZ1, Q8TBM2, Q9H971, Q9H9I4	Gene names	PHC3, EDR3, PH3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3 (hPH3) (Homolog of polyhomeotic 3) (Early development regulatory protein 3).

PP1RA_MOUSE
θ value	6.88961 (rank : 515)	NC score	0.020293 (rank : 407)
Query Neighborhood Hits	587	Target Neighborhood Hits	175	Shared Neighborhood Hits	35
SwissProt Accessions	Q80W00, Q811B6, Q8C6T7, Q8K2U8	Gene names	Ppp1r10, Cat53
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 1 regulatory subunit 10 (MHC class I region proline-rich protein CAT53).

PRAX_HUMAN
θ value	6.88961 (rank : 516)	NC score	0.027014 (rank : 342)
Query Neighborhood Hits	587	Target Neighborhood Hits	215	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

PRPC_HUMAN
θ value	6.88961 (rank : 517)	NC score	0.036257 (rank : 279)
Query Neighborhood Hits	587	Target Neighborhood Hits	165	Shared Neighborhood Hits	42
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

RN169_HUMAN
θ value	6.88961 (rank : 518)	NC score	0.008502 (rank : 551)
Query Neighborhood Hits	587	Target Neighborhood Hits	203	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

RP3A_MOUSE
θ value	6.88961 (rank : 519)	NC score	0.032277 (rank : 306)
Query Neighborhood Hits	587	Target Neighborhood Hits	510	Shared Neighborhood Hits	139
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

RPTN_MOUSE
θ value	6.88961 (rank : 520)	NC score	0.032667 (rank : 302)
Query Neighborhood Hits	587	Target Neighborhood Hits	650	Shared Neighborhood Hits	84
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

SFRIP_HUMAN
θ value	6.88961 (rank : 521)	NC score	0.040741 (rank : 251)
Query Neighborhood Hits	587	Target Neighborhood Hits	530	Shared Neighborhood Hits	76
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

SPHK2_MOUSE
θ value	6.88961 (rank : 522)	NC score	0.012581 (rank : 491)
Query Neighborhood Hits	587	Target Neighborhood Hits	78	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JIA7, Q91VA9, Q9DBH6	Gene names	Sphk2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

SSX4_HUMAN
θ value	6.88961 (rank : 523)	NC score	0.003178 (rank : 612)
Query Neighborhood Hits	587	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	O60224, Q5JQZ0, Q9UJU9	Gene names	SSX4
Domain Architecture
Description	Protein SSX4.

SYN2_HUMAN
θ value	6.88961 (rank : 524)	NC score	0.032432 (rank : 304)
Query Neighborhood Hits	587	Target Neighborhood Hits	213	Shared Neighborhood Hits	53
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

SYNPO_HUMAN
θ value	6.88961 (rank : 525)	NC score	0.037547 (rank : 267)
Query Neighborhood Hits	587	Target Neighborhood Hits	281	Shared Neighborhood Hits	81
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

TMM46_MOUSE
θ value	6.88961 (rank : 526)	NC score	0.008590 (rank : 550)
Query Neighborhood Hits	587	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q8QZV2, Q8BN61	Gene names	Tmem46
Domain Architecture	No domain graphic available
Description	Transmembrane protein 46 homolog precursor.

TR150_MOUSE
θ value	6.88961 (rank : 527)	NC score	0.012860 (rank : 489)
Query Neighborhood Hits	587	Target Neighborhood Hits	468	Shared Neighborhood Hits	41
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

TREX1_HUMAN
θ value	6.88961 (rank : 528)	NC score	0.007017 (rank : 575)
Query Neighborhood Hits	587	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NSU2, Q8TEU2, Q9BPW1, Q9Y4X2	Gene names	TREX1
Domain Architecture
Description	Three prime repair exonuclease 1 (EC 3.1.11.2) (3'-5' exonuclease TREX1) (DNase III).

WASF3_HUMAN
θ value	6.88961 (rank : 529)	NC score	0.025990 (rank : 352)
Query Neighborhood Hits	587	Target Neighborhood Hits	204	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

WBP2_HUMAN
θ value	6.88961 (rank : 530)	NC score	0.009909 (rank : 527)
Query Neighborhood Hits	587	Target Neighborhood Hits	55	Shared Neighborhood Hits	8
SwissProt Accessions	Q969T9, O95638	Gene names	WBP2
Domain Architecture
Description	WW domain-binding protein 2 (WBP-2).

ZN236_HUMAN
θ value	6.88961 (rank : 531)	NC score	-0.003997 (rank : 650)
Query Neighborhood Hits	587	Target Neighborhood Hits	844	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UL36, Q9UL37	Gene names	ZNF236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 236.

ACM4_MOUSE
θ value	8.99809 (rank : 532)	NC score	-0.007539 (rank : 651)
Query Neighborhood Hits	587	Target Neighborhood Hits	894	Shared Neighborhood Hits	13
SwissProt Accessions	P32211, Q64056	Gene names	Chrm4, Chrm-4
Domain Architecture
Description	Muscarinic acetylcholine receptor M4 (Mm4 mAChR).

ARI5B_MOUSE
θ value	8.99809 (rank : 533)	NC score	0.009716 (rank : 532)
Query Neighborhood Hits	587	Target Neighborhood Hits	158	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BM75, Q8C0E0, Q8K4G8, Q8K4L9, Q9CU78, Q9JIX4	Gene names	Arid5b, Desrt, Mrf2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (MRF1-like) (Modulator recognition factor protein 2) (MRF-2) (Developmentally and sexually retarded with transient immune abnormalities protein).

BAG3_MOUSE
θ value	8.99809 (rank : 534)	NC score	0.063751 (rank : 157)
Query Neighborhood Hits	587	Target Neighborhood Hits	513	Shared Neighborhood Hits	160
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

CAD16_HUMAN
θ value	8.99809 (rank : 535)	NC score	0.000643 (rank : 629)
Query Neighborhood Hits	587	Target Neighborhood Hits	159	Shared Neighborhood Hits	9
SwissProt Accessions	O75309, Q6UW93	Gene names	CDH16
Domain Architecture
Description	Cadherin-16 precursor (Kidney-specific cadherin) (Ksp-cadherin).

CD008_HUMAN
θ value	8.99809 (rank : 536)	NC score	0.022030 (rank : 384)
Query Neighborhood Hits	587	Target Neighborhood Hits	330	Shared Neighborhood Hits	49
SwissProt Accessions	P78312, O43607, P78311, P78313, Q9UEG8	Gene names	C4orf8
Domain Architecture	No domain graphic available
Description	Protein C4orf8 (Protein IT14).

CENG3_HUMAN
θ value	8.99809 (rank : 537)	NC score	0.004134 (rank : 605)
Query Neighborhood Hits	587	Target Neighborhood Hits	455	Shared Neighborhood Hits	20
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CN004_HUMAN
θ value	8.99809 (rank : 538)	NC score	0.015469 (rank : 451)
Query Neighborhood Hits	587	Target Neighborhood Hits	108	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H1B7, Q8NDQ2, Q96JG2, Q9H3I7	Gene names	C14orf4, KIAA1865
Domain Architecture	No domain graphic available
Description	Protein C14orf4.

CO3A1_HUMAN
θ value	8.99809 (rank : 539)	NC score	0.027478 (rank : 336)
Query Neighborhood Hits	587	Target Neighborhood Hits	452	Shared Neighborhood Hits	91
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO5A1_HUMAN
θ value	8.99809 (rank : 540)	NC score	0.030425 (rank : 315)
Query Neighborhood Hits	587	Target Neighborhood Hits	434	Shared Neighborhood Hits	91
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

COCA1_MOUSE
θ value	8.99809 (rank : 541)	NC score	0.011074 (rank : 513)
Query Neighborhood Hits	587	Target Neighborhood Hits	467	Shared Neighborhood Hits	58
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COEA1_HUMAN
θ value	8.99809 (rank : 542)	NC score	0.011053 (rank : 514)
Query Neighborhood Hits	587	Target Neighborhood Hits	427	Shared Neighborhood Hits	58
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

COEA1_MOUSE
θ value	8.99809 (rank : 543)	NC score	0.010577 (rank : 518)
Query Neighborhood Hits	587	Target Neighborhood Hits	402	Shared Neighborhood Hits	57
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

CTGE6_HUMAN
θ value	8.99809 (rank : 544)	NC score	0.007942 (rank : 565)
Query Neighborhood Hits	587	Target Neighborhood Hits	650	Shared Neighborhood Hits	43
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

DAB2P_MOUSE
θ value	8.99809 (rank : 545)	NC score	0.006862 (rank : 578)
Query Neighborhood Hits	587	Target Neighborhood Hits	284	Shared Neighborhood Hits	21
SwissProt Accessions	Q3UHC7, Q3TPD5, Q3UH44, Q6JTV1, Q80T97	Gene names	Dab2ip, Kiaa1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein).

DCX_MOUSE
θ value	8.99809 (rank : 546)	NC score	0.013316 (rank : 478)
Query Neighborhood Hits	587	Target Neighborhood Hits	124	Shared Neighborhood Hits	40
SwissProt Accessions	O88809	Gene names	Dcx, Dcn
Domain Architecture
Description	Neuronal migration protein doublecortin (Lissencephalin-X) (Lis-X) (Doublin).

ELK1_HUMAN
θ value	8.99809 (rank : 547)	NC score	0.002590 (rank : 618)
Query Neighborhood Hits	587	Target Neighborhood Hits	112	Shared Neighborhood Hits	17
SwissProt Accessions	P19419, O75606, O95058, Q969X8, Q9UJM4	Gene names	ELK1
Domain Architecture
Description	ETS domain-containing protein Elk-1.

EMID1_HUMAN
θ value	8.99809 (rank : 548)	NC score	0.017114 (rank : 435)
Query Neighborhood Hits	587	Target Neighborhood Hits	215	Shared Neighborhood Hits	51
SwissProt Accessions	Q96A84, Q6ICG1, Q86SS7	Gene names	EMID1, EMU1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

EMIL2_HUMAN
θ value	8.99809 (rank : 549)	NC score	0.008217 (rank : 556)
Query Neighborhood Hits	587	Target Neighborhood Hits	573	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BXX0, Q8NBH3, Q96JQ4	Gene names	EMILIN2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Protein FOAP-10).

EPN1_MOUSE
θ value	8.99809 (rank : 550)	NC score	0.015048 (rank : 454)
Query Neighborhood Hits	587	Target Neighborhood Hits	240	Shared Neighborhood Hits	66
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

FOXC2_MOUSE
θ value	8.99809 (rank : 551)	NC score	0.001429 (rank : 624)
Query Neighborhood Hits	587	Target Neighborhood Hits	124	Shared Neighborhood Hits	10
SwissProt Accessions	Q61850, P97948, Q63869, Q8C694	Gene names	Foxc2, Fkh14, Fkhl14, Mfh1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

FYB_MOUSE
θ value	8.99809 (rank : 552)	NC score	0.014639 (rank : 460)
Query Neighborhood Hits	587	Target Neighborhood Hits	194	Shared Neighborhood Hits	34
SwissProt Accessions	O35601, Q9Z2H3	Gene names	Fyb
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

HES7_HUMAN
θ value	8.99809 (rank : 553)	NC score	0.008890 (rank : 545)
Query Neighborhood Hits	587	Target Neighborhood Hits	72	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BYE0	Gene names	HES7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

HNRPL_HUMAN
θ value	8.99809 (rank : 554)	NC score	0.007759 (rank : 569)
Query Neighborhood Hits	587	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	P14866, Q9H3P3	Gene names	HNRPL
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein L (hnRNP L).

HXB2_HUMAN
θ value	8.99809 (rank : 555)	NC score	0.007580 (rank : 572)
Query Neighborhood Hits	587	Target Neighborhood Hits	367	Shared Neighborhood Hits	31
SwissProt Accessions	P14652, P10913, P17485	Gene names	HOXB2, HOX2H
Domain Architecture
Description	Homeobox protein Hox-B2 (Hox-2H) (Hox-2.8) (K8).

ITIH1_MOUSE
θ value	8.99809 (rank : 556)	NC score	0.002457 (rank : 620)
Query Neighborhood Hits	587	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q61702	Gene names	Itih1
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H1 precursor (ITI heavy chain H1) (Inter-alpha-inhibitor heavy chain 1).

JUNB_MOUSE
θ value	8.99809 (rank : 557)	NC score	0.004911 (rank : 598)
Query Neighborhood Hits	587	Target Neighborhood Hits	116	Shared Neighborhood Hits	12
SwissProt Accessions	P09450, Q8C2G9	Gene names	Junb, Jun-b
Domain Architecture
Description	Transcription factor jun-B.

KCNG4_HUMAN
θ value	8.99809 (rank : 558)	NC score	0.077628 (rank : 115)
Query Neighborhood Hits	587	Target Neighborhood Hits	99	Shared Neighborhood Hits	28
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNH2_MOUSE
θ value	8.99809 (rank : 559)	NC score	0.015255 (rank : 453)
Query Neighborhood Hits	587	Target Neighborhood Hits	165	Shared Neighborhood Hits	34
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

LCP2_HUMAN
θ value	8.99809 (rank : 560)	NC score	0.073437 (rank : 126)
Query Neighborhood Hits	587	Target Neighborhood Hits	531	Shared Neighborhood Hits	157
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LUZP1_MOUSE
θ value	8.99809 (rank : 561)	NC score	0.004935 (rank : 597)
Query Neighborhood Hits	587	Target Neighborhood Hits	940	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

MCLN3_HUMAN
θ value	8.99809 (rank : 562)	NC score	0.024313 (rank : 364)
Query Neighborhood Hits	587	Target Neighborhood Hits	26	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TDD5, Q5T4H5, Q5T4H6, Q9NV09	Gene names	MCOLN3
Domain Architecture	No domain graphic available
Description	Mucolipin-3.

MMP9_HUMAN
θ value	8.99809 (rank : 563)	NC score	0.000740 (rank : 628)
Query Neighborhood Hits	587	Target Neighborhood Hits	125	Shared Neighborhood Hits	15
SwissProt Accessions	P14780, Q3LR70, Q8N725, Q9H4Z1	Gene names	MMP9, CLG4B
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB) [Contains: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9].

MS3L1_HUMAN
θ value	8.99809 (rank : 564)	NC score	0.008037 (rank : 563)
Query Neighborhood Hits	587	Target Neighborhood Hits	60	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N5Y2, Q9UG70, Q9Y5Z8	Gene names	MSL3L1
Domain Architecture
Description	Male-specific lethal 3-like 1 (MSL3-like 1) (Male-specific lethal-3 homolog 1).

MTSS1_MOUSE
θ value	8.99809 (rank : 565)	NC score	0.058325 (rank : 181)
Query Neighborhood Hits	587	Target Neighborhood Hits	592	Shared Neighborhood Hits	168
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

PANK1_MOUSE
θ value	8.99809 (rank : 566)	NC score	0.003353 (rank : 610)
Query Neighborhood Hits	587	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K4K6, Q9D3K1, Q9QXM8	Gene names	Pank1, Pank
Domain Architecture
Description	Pantothenate kinase 1 (EC 2.7.1.33) (Pantothenic acid kinase 1) (mPank1) (mPank).

PCGF2_MOUSE
θ value	8.99809 (rank : 567)	NC score	0.003350 (rank : 611)
Query Neighborhood Hits	587	Target Neighborhood Hits	213	Shared Neighborhood Hits	15
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PDXL2_HUMAN
θ value	8.99809 (rank : 568)	NC score	0.008120 (rank : 560)
Query Neighborhood Hits	587	Target Neighborhood Hits	75	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NZ53, Q6UVY4, Q8WUV6	Gene names	PODXL2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

PHLB1_HUMAN
θ value	8.99809 (rank : 569)	NC score	0.039023 (rank : 261)
Query Neighborhood Hits	587	Target Neighborhood Hits	1038	Shared Neighborhood Hits	154
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PKDRE_MOUSE
θ value	8.99809 (rank : 570)	NC score	0.072104 (rank : 130)
Query Neighborhood Hits	587	Target Neighborhood Hits	76	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

PMS2_HUMAN
θ value	8.99809 (rank : 571)	NC score	0.008469 (rank : 552)
Query Neighborhood Hits	587	Target Neighborhood Hits	131	Shared Neighborhood Hits	26
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

POLS2_MOUSE
θ value	8.99809 (rank : 572)	NC score	-0.003820 (rank : 649)
Query Neighborhood Hits	587	Target Neighborhood Hits	188	Shared Neighborhood Hits	2
SwissProt Accessions	Q5K2P8	Gene names	Prss36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

RHG06_HUMAN
θ value	8.99809 (rank : 573)	NC score	0.008163 (rank : 558)
Query Neighborhood Hits	587	Target Neighborhood Hits	114	Shared Neighborhood Hits	18
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RXRB_MOUSE
θ value	8.99809 (rank : 574)	NC score	0.003024 (rank : 615)
Query Neighborhood Hits	587	Target Neighborhood Hits	230	Shared Neighborhood Hits	37
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

SAM14_MOUSE
θ value	8.99809 (rank : 575)	NC score	0.013233 (rank : 480)
Query Neighborhood Hits	587	Target Neighborhood Hits	91	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K070, Q5SWB7, Q8BHE2, Q8C8N5	Gene names	Samd14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

SATB1_MOUSE
θ value	8.99809 (rank : 576)	NC score	0.005517 (rank : 592)
Query Neighborhood Hits	587	Target Neighborhood Hits	130	Shared Neighborhood Hits	20
SwissProt Accessions	Q60611	Gene names	Satb1
Domain Architecture
Description	DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1).

SC24D_HUMAN
θ value	8.99809 (rank : 577)	NC score	0.013901 (rank : 469)
Query Neighborhood Hits	587	Target Neighborhood Hits	173	Shared Neighborhood Hits	40
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

SDK1_HUMAN
θ value	8.99809 (rank : 578)	NC score	-0.000615 (rank : 637)
Query Neighborhood Hits	587	Target Neighborhood Hits	511	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SIX5_HUMAN
θ value	8.99809 (rank : 579)	NC score	0.008599 (rank : 549)
Query Neighborhood Hits	587	Target Neighborhood Hits	386	Shared Neighborhood Hits	47
SwissProt Accessions	Q8N196	Gene names	SIX5, DMAHP
Domain Architecture	No domain graphic available
Description	Homeobox protein SIX5 (DM locus-associated homeodomain protein).

SMAL1_MOUSE
θ value	8.99809 (rank : 580)	NC score	0.008894 (rank : 544)
Query Neighborhood Hits	587	Target Neighborhood Hits	157	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

SPRE3_HUMAN
θ value	8.99809 (rank : 581)	NC score	0.012076 (rank : 496)
Query Neighborhood Hits	587	Target Neighborhood Hits	65	Shared Neighborhood Hits	23
SwissProt Accessions	Q2MJR0	Gene names	SPRED3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).

TRPV3_HUMAN
θ value	8.99809 (rank : 582)	NC score	0.059553 (rank : 179)
Query Neighborhood Hits	587	Target Neighborhood Hits	198	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

UBP31_HUMAN
θ value	8.99809 (rank : 583)	NC score	0.011611 (rank : 504)
Query Neighborhood Hits	587	Target Neighborhood Hits	293	Shared Neighborhood Hits	47
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

WASF3_MOUSE
θ value	8.99809 (rank : 584)	NC score	0.023148 (rank : 372)
Query Neighborhood Hits	587	Target Neighborhood Hits	188	Shared Neighborhood Hits	51
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

YAP1_MOUSE
θ value	8.99809 (rank : 585)	NC score	0.004020 (rank : 606)
Query Neighborhood Hits	587	Target Neighborhood Hits	96	Shared Neighborhood Hits	14
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

ZC3H3_HUMAN
θ value	8.99809 (rank : 586)	NC score	0.021780 (rank : 386)
Query Neighborhood Hits	587	Target Neighborhood Hits	159	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IXZ2, Q14163, Q8N4E2, Q9BUS4	Gene names	ZC3H3, KIAA0150, ZC3HDC3
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

ZMYM3_HUMAN
θ value	8.99809 (rank : 587)	NC score	0.009524 (rank : 536)
Query Neighborhood Hits	587	Target Neighborhood Hits	223	Shared Neighborhood Hits	45
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

CABIN_HUMAN
θ value	θ > 10 (rank : 588)	NC score	0.050959 (rank : 217)
Query Neighborhood Hits	587	Target Neighborhood Hits	490	Shared Neighborhood Hits	134
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CBP_MOUSE
θ value	θ > 10 (rank : 589)	NC score	0.061686 (rank : 163)
Query Neighborhood Hits	587	Target Neighborhood Hits	1051	Shared Neighborhood Hits	209
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CD2_HUMAN
θ value	θ > 10 (rank : 590)	NC score	0.071054 (rank : 132)
Query Neighborhood Hits	587	Target Neighborhood Hits	504	Shared Neighborhood Hits	156
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CECR2_HUMAN
θ value	θ > 10 (rank : 591)	NC score	0.053073 (rank : 209)
Query Neighborhood Hits	587	Target Neighborhood Hits	543	Shared Neighborhood Hits	169
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

CEL_HUMAN
θ value	θ > 10 (rank : 592)	NC score	0.063844 (rank : 156)
Query Neighborhood Hits	587	Target Neighborhood Hits	896	Shared Neighborhood Hits	231
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CK024_HUMAN
θ value	θ > 10 (rank : 593)	NC score	0.055032 (rank : 199)
Query Neighborhood Hits	587	Target Neighborhood Hits	408	Shared Neighborhood Hits	127
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CO039_MOUSE
θ value	θ > 10 (rank : 594)	NC score	0.064133 (rank : 154)
Query Neighborhood Hits	587	Target Neighborhood Hits	445	Shared Neighborhood Hits	145
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

CSF1_HUMAN
θ value	θ > 10 (rank : 595)	NC score	0.057422 (rank : 188)
Query Neighborhood Hits	587	Target Neighborhood Hits	258	Shared Neighborhood Hits	108
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

FA47A_HUMAN
θ value	θ > 10 (rank : 596)	NC score	0.069623 (rank : 138)
Query Neighborhood Hits	587	Target Neighborhood Hits	451	Shared Neighborhood Hits	136
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

FA47B_HUMAN
θ value	θ > 10 (rank : 597)	NC score	0.066671 (rank : 145)
Query Neighborhood Hits	587	Target Neighborhood Hits	431	Shared Neighborhood Hits	139
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

GA2L2_MOUSE
θ value	θ > 10 (rank : 598)	NC score	0.052587 (rank : 210)
Query Neighborhood Hits	587	Target Neighborhood Hits	395	Shared Neighborhood Hits	139
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

IASPP_MOUSE
θ value	θ > 10 (rank : 599)	NC score	0.050299 (rank : 221)
Query Neighborhood Hits	587	Target Neighborhood Hits	1024	Shared Neighborhood Hits	216
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IWS1_MOUSE
θ value	θ > 10 (rank : 600)	NC score	0.065543 (rank : 150)
Query Neighborhood Hits	587	Target Neighborhood Hits	1258	Shared Neighborhood Hits	175
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

KCNA1_HUMAN
θ value	θ > 10 (rank : 601)	NC score	0.090039 (rank : 84)
Query Neighborhood Hits	587	Target Neighborhood Hits	104	Shared Neighborhood Hits	39
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNA1_MOUSE
θ value	θ > 10 (rank : 602)	NC score	0.092230 (rank : 79)
Query Neighborhood Hits	587	Target Neighborhood Hits	103	Shared Neighborhood Hits	40
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNA3_HUMAN
θ value	θ > 10 (rank : 603)	NC score	0.078137 (rank : 111)
Query Neighborhood Hits	587	Target Neighborhood Hits	101	Shared Neighborhood Hits	35
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNA3_MOUSE
θ value	θ > 10 (rank : 604)	NC score	0.076194 (rank : 119)
Query Neighborhood Hits	587	Target Neighborhood Hits	103	Shared Neighborhood Hits	33
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCNA4_HUMAN
θ value	θ > 10 (rank : 605)	NC score	0.065310 (rank : 151)
Query Neighborhood Hits	587	Target Neighborhood Hits	108	Shared Neighborhood Hits	29
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNA4_MOUSE
θ value	θ > 10 (rank : 606)	NC score	0.065699 (rank : 149)
Query Neighborhood Hits	587	Target Neighborhood Hits	98	Shared Neighborhood Hits	29
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNA5_HUMAN
θ value	θ > 10 (rank : 607)	NC score	0.074281 (rank : 125)
Query Neighborhood Hits	587	Target Neighborhood Hits	124	Shared Neighborhood Hits	35
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNA5_MOUSE
θ value	θ > 10 (rank : 608)	NC score	0.078769 (rank : 109)
Query Neighborhood Hits	587	Target Neighborhood Hits	119	Shared Neighborhood Hits	37
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCNA6_HUMAN
θ value	θ > 10 (rank : 609)	NC score	0.080724 (rank : 106)
Query Neighborhood Hits	587	Target Neighborhood Hits	100	Shared Neighborhood Hits	36
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNA6_MOUSE
θ value	θ > 10 (rank : 610)	NC score	0.083384 (rank : 101)
Query Neighborhood Hits	587	Target Neighborhood Hits	106	Shared Neighborhood Hits	40
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNC3_HUMAN
θ value	θ > 10 (rank : 611)	NC score	0.124659 (rank : 58)
Query Neighborhood Hits	587	Target Neighborhood Hits	256	Shared Neighborhood Hits	94
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC3_MOUSE
θ value	θ > 10 (rank : 612)	NC score	0.119982 (rank : 61)
Query Neighborhood Hits	587	Target Neighborhood Hits	173	Shared Neighborhood Hits	62
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC4_HUMAN
θ value	θ > 10 (rank : 613)	NC score	0.132980 (rank : 55)
Query Neighborhood Hits	587	Target Neighborhood Hits	141	Shared Neighborhood Hits	54
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KCNC4_MOUSE
θ value	θ > 10 (rank : 614)	NC score	0.122137 (rank : 59)
Query Neighborhood Hits	587	Target Neighborhood Hits	130	Shared Neighborhood Hits	52
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCNG1_HUMAN
θ value	θ > 10 (rank : 615)	NC score	0.082425 (rank : 102)
Query Neighborhood Hits	587	Target Neighborhood Hits	103	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNG2_HUMAN
θ value	θ > 10 (rank : 616)	NC score	0.080089 (rank : 107)
Query Neighborhood Hits	587	Target Neighborhood Hits	83	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNQ1_HUMAN
θ value	θ > 10 (rank : 617)	NC score	0.070960 (rank : 133)
Query Neighborhood Hits	587	Target Neighborhood Hits	99	Shared Neighborhood Hits	37
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ2_HUMAN
θ value	θ > 10 (rank : 618)	NC score	0.057448 (rank : 187)
Query Neighborhood Hits	587	Target Neighborhood Hits	114	Shared Neighborhood Hits	41
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ2_MOUSE
θ value	θ > 10 (rank : 619)	NC score	0.057023 (rank : 190)
Query Neighborhood Hits	587	Target Neighborhood Hits	163	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ4_HUMAN
θ value	θ > 10 (rank : 620)	NC score	0.081552 (rank : 104)
Query Neighborhood Hits	587	Target Neighborhood Hits	136	Shared Neighborhood Hits	43
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCNQ5_HUMAN
θ value	θ > 10 (rank : 621)	NC score	0.070823 (rank : 135)
Query Neighborhood Hits	587	Target Neighborhood Hits	163	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

LPP_HUMAN
θ value	θ > 10 (rank : 622)	NC score	0.059585 (rank : 178)
Query Neighborhood Hits	587	Target Neighborhood Hits	775	Shared Neighborhood Hits	219
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

MARCS_HUMAN
θ value	θ > 10 (rank : 623)	NC score	0.051973 (rank : 213)
Query Neighborhood Hits	587	Target Neighborhood Hits	204	Shared Neighborhood Hits	37
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MBB1A_HUMAN
θ value	θ > 10 (rank : 624)	NC score	0.055281 (rank : 195)
Query Neighborhood Hits	587	Target Neighborhood Hits	665	Shared Neighborhood Hits	164
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MDC1_HUMAN
θ value	θ > 10 (rank : 625)	NC score	0.079979 (rank : 108)
Query Neighborhood Hits	587	Target Neighborhood Hits	1446	Shared Neighborhood Hits	242
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MDC1_MOUSE
θ value	θ > 10 (rank : 626)	NC score	0.086700 (rank : 90)
Query Neighborhood Hits	587	Target Neighborhood Hits	998	Shared Neighborhood Hits	215
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MISS_MOUSE
θ value	θ > 10 (rank : 627)	NC score	0.061529 (rank : 164)
Query Neighborhood Hits	587	Target Neighborhood Hits	444	Shared Neighborhood Hits	143
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

MKL1_MOUSE
θ value	θ > 10 (rank : 628)	NC score	0.060052 (rank : 173)
Query Neighborhood Hits	587	Target Neighborhood Hits	667	Shared Neighborhood Hits	193
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

MUC1_HUMAN
θ value	θ > 10 (rank : 629)	NC score	0.115667 (rank : 63)
Query Neighborhood Hits	587	Target Neighborhood Hits	975	Shared Neighborhood Hits	270
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MUCDL_HUMAN
θ value	θ > 10 (rank : 630)	NC score	0.053724 (rank : 206)
Query Neighborhood Hits	587	Target Neighborhood Hits	777	Shared Neighborhood Hits	194
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NCOA6_HUMAN
θ value	θ > 10 (rank : 631)	NC score	0.100129 (rank : 72)
Query Neighborhood Hits	587	Target Neighborhood Hits	1202	Shared Neighborhood Hits	294
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NCOA6_MOUSE
θ value	θ > 10 (rank : 632)	NC score	0.081782 (rank : 103)
Query Neighborhood Hits	587	Target Neighborhood Hits	1076	Shared Neighborhood Hits	251
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NIPBL_HUMAN
θ value	θ > 10 (rank : 633)	NC score	0.055389 (rank : 194)
Query Neighborhood Hits	587	Target Neighborhood Hits	1311	Shared Neighborhood Hits	170
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NPBL_MOUSE
θ value	θ > 10 (rank : 634)	NC score	0.060418 (rank : 170)
Query Neighborhood Hits	587	Target Neighborhood Hits	1041	Shared Neighborhood Hits	157
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

OGFR_HUMAN
θ value	θ > 10 (rank : 635)	NC score	0.117296 (rank : 62)
Query Neighborhood Hits	587	Target Neighborhood Hits	1582	Shared Neighborhood Hits	343
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PSL1_HUMAN
θ value	θ > 10 (rank : 636)	NC score	0.060144 (rank : 172)
Query Neighborhood Hits	587	Target Neighborhood Hits	650	Shared Neighborhood Hits	202
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RGS3_HUMAN
θ value	θ > 10 (rank : 637)	NC score	0.073323 (rank : 128)
Query Neighborhood Hits	587	Target Neighborhood Hits	1375	Shared Neighborhood Hits	300
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RGS3_MOUSE
θ value	θ > 10 (rank : 638)	NC score	0.100594 (rank : 71)
Query Neighborhood Hits	587	Target Neighborhood Hits	1621	Shared Neighborhood Hits	342
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SC24C_HUMAN
θ value	θ > 10 (rank : 639)	NC score	0.069009 (rank : 140)
Query Neighborhood Hits	587	Target Neighborhood Hits	662	Shared Neighborhood Hits	211
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SELPL_MOUSE
θ value	θ > 10 (rank : 640)	NC score	0.069303 (rank : 139)
Query Neighborhood Hits	587	Target Neighborhood Hits	588	Shared Neighborhood Hits	156
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SNPC4_HUMAN
θ value	θ > 10 (rank : 641)	NC score	0.074336 (rank : 124)
Query Neighborhood Hits	587	Target Neighborhood Hits	589	Shared Neighborhood Hits	188
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

SON_HUMAN
θ value	θ > 10 (rank : 642)	NC score	0.093324 (rank : 78)
Query Neighborhood Hits	587	Target Neighborhood Hits	1568	Shared Neighborhood Hits	318
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SPR1B_MOUSE
θ value	θ > 10 (rank : 643)	NC score	0.054314 (rank : 204)
Query Neighborhood Hits	587	Target Neighborhood Hits	395	Shared Neighborhood Hits	137
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

SSBP4_HUMAN
θ value	θ > 10 (rank : 644)	NC score	0.070943 (rank : 134)
Query Neighborhood Hits	587	Target Neighborhood Hits	753	Shared Neighborhood Hits	238
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

T22D4_HUMAN
θ value	θ > 10 (rank : 645)	NC score	0.052562 (rank : 211)
Query Neighborhood Hits	587	Target Neighborhood Hits	403	Shared Neighborhood Hits	144
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

TAF4_HUMAN
θ value	θ > 10 (rank : 646)	NC score	0.062161 (rank : 161)
Query Neighborhood Hits	587	Target Neighborhood Hits	687	Shared Neighborhood Hits	125
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TARA_MOUSE
θ value	θ > 10 (rank : 647)	NC score	0.051725 (rank : 214)
Query Neighborhood Hits	587	Target Neighborhood Hits	1133	Shared Neighborhood Hits	144
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TAU_MOUSE
θ value	θ > 10 (rank : 648)	NC score	0.051442 (rank : 215)
Query Neighborhood Hits	587	Target Neighborhood Hits	502	Shared Neighborhood Hits	129
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TGON2_HUMAN
θ value	θ > 10 (rank : 649)	NC score	0.073057 (rank : 129)
Query Neighborhood Hits	587	Target Neighborhood Hits	1037	Shared Neighborhood Hits	178
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TP53B_MOUSE
θ value	θ > 10 (rank : 650)	NC score	0.052020 (rank : 212)
Query Neighborhood Hits	587	Target Neighborhood Hits	644	Shared Neighborhood Hits	122
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TXND2_HUMAN
θ value	θ > 10 (rank : 651)	NC score	0.057229 (rank : 189)
Query Neighborhood Hits	587	Target Neighborhood Hits	793	Shared Neighborhood Hits	138
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

ZN385_HUMAN
θ value	θ > 10 (rank : 652)	NC score	0.058051 (rank : 183)
Query Neighborhood Hits	587	Target Neighborhood Hits	614	Shared Neighborhood Hits	181
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

Hits sorted by NC score

CAC1G_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	587	Target Neighborhood Hits	587	Shared Neighborhood Hits	587
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CAC1H_MOUSE
NC score	0.955236 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	587	Target Neighborhood Hits	230	Shared Neighborhood Hits	105
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CAC1I_HUMAN
NC score	0.951967 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	587	Target Neighborhood Hits	138	Shared Neighborhood Hits	78
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

CAC1H_HUMAN
NC score	0.951156 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	587	Target Neighborhood Hits	307	Shared Neighborhood Hits	127
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

SC11A_HUMAN
NC score	0.866908 (rank : 5)	θ value	7.19216e-82 (rank : 5)
Query Neighborhood Hits	587	Target Neighborhood Hits	111	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

SC11A_MOUSE
NC score	0.866486 (rank : 6)	θ value	2.92676e-75 (rank : 6)
Query Neighborhood Hits	587	Target Neighborhood Hits	116	Shared Neighborhood Hits	67
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

CAC1E_MOUSE
NC score	0.863495 (rank : 7)	θ value	9.11921e-69 (rank : 14)
Query Neighborhood Hits	587	Target Neighborhood Hits	167	Shared Neighborhood Hits	68
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_HUMAN
NC score	0.863269 (rank : 8)	θ value	6.98233e-69 (rank : 13)
Query Neighborhood Hits	587	Target Neighborhood Hits	148	Shared Neighborhood Hits	66
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1A_HUMAN
NC score	0.859398 (rank : 9)	θ value	9.43692e-66 (rank : 18)
Query Neighborhood Hits	587	Target Neighborhood Hits	387	Shared Neighborhood Hits	150
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

SCN4A_HUMAN
NC score	0.859332 (rank : 10)	θ value	2.09745e-73 (rank : 7)
Query Neighborhood Hits	587	Target Neighborhood Hits	133	Shared Neighborhood Hits	66
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

CAC1A_MOUSE
NC score	0.858457 (rank : 11)	θ value	2.74572e-65 (rank : 19)
Query Neighborhood Hits	587	Target Neighborhood Hits	267	Shared Neighborhood Hits	102
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1B_MOUSE
NC score	0.858435 (rank : 12)	θ value	2.93355e-67 (rank : 17)
Query Neighborhood Hits	587	Target Neighborhood Hits	351	Shared Neighborhood Hits	139
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

SCN5A_HUMAN
NC score	0.858302 (rank : 13)	θ value	1.96772e-63 (rank : 22)
Query Neighborhood Hits	587	Target Neighborhood Hits	145	Shared Neighborhood Hits	69
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

CAC1S_MOUSE
NC score	0.858005 (rank : 14)	θ value	2.17053e-70 (rank : 10)
Query Neighborhood Hits	587	Target Neighborhood Hits	98	Shared Neighborhood Hits	66
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1D_HUMAN
NC score	0.856943 (rank : 15)	θ value	4.83544e-70 (rank : 12)
Query Neighborhood Hits	587	Target Neighborhood Hits	118	Shared Neighborhood Hits	65
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CAC1S_HUMAN
NC score	0.856547 (rank : 16)	θ value	1.31681e-67 (rank : 16)
Query Neighborhood Hits	587	Target Neighborhood Hits	92	Shared Neighborhood Hits	61
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1B_HUMAN
NC score	0.856329 (rank : 17)	θ value	3.71096e-62 (rank : 24)
Query Neighborhood Hits	587	Target Neighborhood Hits	257	Shared Neighborhood Hits	90
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

SCN3A_HUMAN
NC score	0.853204 (rank : 18)	θ value	1.27248e-70 (rank : 9)
Query Neighborhood Hits	587	Target Neighborhood Hits	115	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

CAC1F_HUMAN
NC score	0.852978 (rank : 19)	θ value	1.15359e-63 (rank : 21)
Query Neighborhood Hits	587	Target Neighborhood Hits	141	Shared Neighborhood Hits	70
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

SCN7A_HUMAN
NC score	0.852488 (rank : 20)	θ value	8.00737e-57 (rank : 30)
Query Neighborhood Hits	587	Target Neighborhood Hits	135	Shared Neighborhood Hits	55
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

CAC1F_MOUSE
NC score	0.852116 (rank : 21)	θ value	9.76566e-63 (rank : 23)
Query Neighborhood Hits	587	Target Neighborhood Hits	142	Shared Neighborhood Hits	68
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1C_MOUSE
NC score	0.850315 (rank : 22)	θ value	2.32439e-64 (rank : 20)
Query Neighborhood Hits	587	Target Neighborhood Hits	130	Shared Neighborhood Hits	60
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

SCN2A_HUMAN
NC score	0.850154 (rank : 23)	θ value	9.74306e-71 (rank : 8)
Query Neighborhood Hits	587	Target Neighborhood Hits	157	Shared Neighborhood Hits	62
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SCN1A_HUMAN
NC score	0.849262 (rank : 24)	θ value	3.70236e-70 (rank : 11)
Query Neighborhood Hits	587	Target Neighborhood Hits	148	Shared Neighborhood Hits	59
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

SCN9A_HUMAN
NC score	0.848899 (rank : 25)	θ value	1.00825e-67 (rank : 15)
Query Neighborhood Hits	587	Target Neighborhood Hits	157	Shared Neighborhood Hits	61
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

SC10A_MOUSE
NC score	0.848264 (rank : 26)	θ value	6.32992e-62 (rank : 25)
Query Neighborhood Hits	587	Target Neighborhood Hits	107	Shared Neighborhood Hits	61
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

SCN8A_HUMAN
NC score	0.847406 (rank : 27)	θ value	5.92465e-60 (rank : 28)
Query Neighborhood Hits	587	Target Neighborhood Hits	135	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SC10A_HUMAN
NC score	0.847021 (rank : 28)	θ value	4.10295e-61 (rank : 26)
Query Neighborhood Hits	587	Target Neighborhood Hits	116	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

SCN8A_MOUSE
NC score	0.845347 (rank : 29)	θ value	4.53632e-60 (rank : 27)
Query Neighborhood Hits	587	Target Neighborhood Hits	136	Shared Neighborhood Hits	63
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

CAC1C_HUMAN
NC score	0.844169 (rank : 30)	θ value	4.24587e-58 (rank : 29)
Query Neighborhood Hits	587	Target Neighborhood Hits	158	Shared Neighborhood Hits	59
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

PK2L2_HUMAN
NC score	0.299840 (rank : 31)	θ value	0.0736092 (rank : 105)
Query Neighborhood Hits	587	Target Neighborhood Hits	90	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PK2L1_HUMAN
NC score	0.283570 (rank : 32)	θ value	0.0431538 (rank : 93)
Query Neighborhood Hits	587	Target Neighborhood Hits	132	Shared Neighborhood Hits	43
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

PK2L2_MOUSE
NC score	0.268766 (rank : 33)	θ value	0.0431538 (rank : 94)
Query Neighborhood Hits	587	Target Neighborhood Hits	84	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PKD2_MOUSE
NC score	0.263361 (rank : 34)	θ value	0.0961366 (rank : 119)
Query Neighborhood Hits	587	Target Neighborhood Hits	99	Shared Neighborhood Hits	44
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

PKD2_HUMAN
NC score	0.248595 (rank : 35)	θ value	0.813845 (rank : 227)
Query Neighborhood Hits	587	Target Neighborhood Hits	105	Shared Neighborhood Hits	44
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

KCNV2_HUMAN
NC score	0.239519 (rank : 36)	θ value	2.88788e-06 (rank : 31)
Query Neighborhood Hits	587	Target Neighborhood Hits	137	Shared Neighborhood Hits	55
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCNF1_HUMAN
NC score	0.235979 (rank : 37)	θ value	0.000602161 (rank : 46)
Query Neighborhood Hits	587	Target Neighborhood Hits	109	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCNB2_HUMAN
NC score	0.224058 (rank : 38)	θ value	0.00134147 (rank : 52)
Query Neighborhood Hits	587	Target Neighborhood Hits	212	Shared Neighborhood Hits	76
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNS2_MOUSE
NC score	0.220624 (rank : 39)	θ value	9.29e-05 (rank : 35)
Query Neighborhood Hits	587	Target Neighborhood Hits	130	Shared Neighborhood Hits	57
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_HUMAN
NC score	0.216212 (rank : 40)	θ value	0.000158464 (rank : 37)
Query Neighborhood Hits	587	Target Neighborhood Hits	129	Shared Neighborhood Hits	56
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNB1_HUMAN
NC score	0.211826 (rank : 41)	θ value	0.00102713 (rank : 49)
Query Neighborhood Hits	587	Target Neighborhood Hits	169	Shared Neighborhood Hits	62
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNB1_MOUSE
NC score	0.211356 (rank : 42)	θ value	0.00102713 (rank : 50)
Query Neighborhood Hits	587	Target Neighborhood Hits	154	Shared Neighborhood Hits	59
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNS3_HUMAN
NC score	0.188135 (rank : 43)	θ value	0.00390308 (rank : 57)
Query Neighborhood Hits	587	Target Neighborhood Hits	125	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

KCND3_MOUSE
NC score	0.176913 (rank : 44)	θ value	0.0330416 (rank : 83)
Query Neighborhood Hits	587	Target Neighborhood Hits	162	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_HUMAN
NC score	0.176758 (rank : 45)	θ value	0.0330416 (rank : 82)
Query Neighborhood Hits	587	Target Neighborhood Hits	162	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND2_MOUSE
NC score	0.173494 (rank : 46)	θ value	0.279714 (rank : 151)
Query Neighborhood Hits	587	Target Neighborhood Hits	156	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_HUMAN
NC score	0.173093 (rank : 47)	θ value	0.279714 (rank : 150)
Query Neighborhood Hits	587	Target Neighborhood Hits	154	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

TPTE2_HUMAN
NC score	0.170256 (rank : 48)	θ value	0.0431538 (rank : 95)
Query Neighborhood Hits	587	Target Neighborhood Hits	68	Shared Neighborhood Hits	27
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

KCNS1_HUMAN
NC score	0.164256 (rank : 49)	θ value	0.0193708 (rank : 71)
Query Neighborhood Hits	587	Target Neighborhood Hits	116	Shared Neighborhood Hits	55
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCND1_MOUSE
NC score	0.154782 (rank : 50)	θ value	0.62314 (rank : 193)
Query Neighborhood Hits	587	Target Neighborhood Hits	165	Shared Neighborhood Hits	59
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCND1_HUMAN
NC score	0.154723 (rank : 51)	θ value	0.163984 (rank : 134)
Query Neighborhood Hits	587	Target Neighborhood Hits	160	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCNS1_MOUSE
NC score	0.153028 (rank : 52)	θ value	0.0330416 (rank : 84)
Query Neighborhood Hits	587	Target Neighborhood Hits	114	Shared Neighborhood Hits	49
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNC1_HUMAN
NC score	0.148994 (rank : 53)	θ value	0.163984 (rank : 132)
Query Neighborhood Hits	587	Target Neighborhood Hits	133	Shared Neighborhood Hits	52
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC1_MOUSE
NC score	0.147611 (rank : 54)	θ value	0.163984 (rank : 133)
Query Neighborhood Hits	587	Target Neighborhood Hits	133	Shared Neighborhood Hits	52
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC4_HUMAN
NC score	0.132980 (rank : 55)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	587	Target Neighborhood Hits	141	Shared Neighborhood Hits	54
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

PRRT3_HUMAN
NC score	0.129503 (rank : 56)	θ value	5.27518 (rank : 472)
Query Neighborhood Hits	587	Target Neighborhood Hits	998	Shared Neighborhood Hits	296
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

BSN_MOUSE
NC score	0.127345 (rank : 57)	θ value	7.1131e-05 (rank : 34)
Query Neighborhood Hits	587	Target Neighborhood Hits	2057	Shared Neighborhood Hits	341
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

KCNC3_HUMAN
NC score	0.124659 (rank : 58)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	587	Target Neighborhood Hits	256	Shared Neighborhood Hits	94
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC4_MOUSE
NC score	0.122137 (rank : 59)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	587	Target Neighborhood Hits	130	Shared Neighborhood Hits	52
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

TPTE_HUMAN
NC score	0.120682 (rank : 60)	θ value	1.81305 (rank : 310)
Query Neighborhood Hits	587	Target Neighborhood Hits	53	Shared Neighborhood Hits	25
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

KCNC3_MOUSE
NC score	0.119982 (rank : 61)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	587	Target Neighborhood Hits	173	Shared Neighborhood Hits	62
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

OGFR_HUMAN
NC score	0.117296 (rank : 62)	θ value	θ > 10 (rank : 635)
Query Neighborhood Hits	587	Target Neighborhood Hits	1582	Shared Neighborhood Hits	343
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

MUC1_HUMAN
NC score	0.115667 (rank : 63)	θ value	θ > 10 (rank : 629)
Query Neighborhood Hits	587	Target Neighborhood Hits	975	Shared Neighborhood Hits	270
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

SRRM1_MOUSE
NC score	0.115433 (rank : 64)	θ value	0.000461057 (rank : 45)
Query Neighborhood Hits	587	Target Neighborhood Hits	966	Shared Neighborhood Hits	208
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

KCNG3_HUMAN
NC score	0.112360 (rank : 65)	θ value	1.38821 (rank : 265)
Query Neighborhood Hits	587	Target Neighborhood Hits	91	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNG3_MOUSE
NC score	0.111613 (rank : 66)	θ value	0.62314 (rank : 194)
Query Neighborhood Hits	587	Target Neighborhood Hits	91	Shared Neighborhood Hits	43
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

NACAM_MOUSE
NC score	0.109324 (rank : 67)	θ value	0.62314 (rank : 199)
Query Neighborhood Hits	587	Target Neighborhood Hits	1866	Shared Neighborhood Hits	336
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PKDRE_HUMAN
NC score	0.101955 (rank : 68)	θ value	0.365318 (rank : 165)
Query Neighborhood Hits	587	Target Neighborhood Hits	64	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

BAT2_HUMAN
NC score	0.101272 (rank : 69)	θ value	0.0148317 (rank : 67)
Query Neighborhood Hits	587	Target Neighborhood Hits	931	Shared Neighborhood Hits	214
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BSN_HUMAN
NC score	0.100746 (rank : 70)	θ value	0.00020696 (rank : 38)
Query Neighborhood Hits	587	Target Neighborhood Hits	1537	Shared Neighborhood Hits	238
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

RGS3_MOUSE
NC score	0.100594 (rank : 71)	θ value	θ > 10 (rank : 638)
Query Neighborhood Hits	587	Target Neighborhood Hits	1621	Shared Neighborhood Hits	342
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

NCOA6_HUMAN
NC score	0.100129 (rank : 72)	θ value	θ > 10 (rank : 631)
Query Neighborhood Hits	587	Target Neighborhood Hits	1202	Shared Neighborhood Hits	294
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

BAT2_MOUSE
NC score	0.099439 (rank : 73)	θ value	0.0330416 (rank : 79)
Query Neighborhood Hits	587	Target Neighborhood Hits	947	Shared Neighborhood Hits	233
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

PRP5_HUMAN
NC score	0.097643 (rank : 74)	θ value	0.0736092 (rank : 106)
Query Neighborhood Hits	587	Target Neighborhood Hits	108	Shared Neighborhood Hits	38
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

BCL9_HUMAN
NC score	0.097473 (rank : 75)	θ value	1.38821 (rank : 255)
Query Neighborhood Hits	587	Target Neighborhood Hits	1008	Shared Neighborhood Hits	249
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

SRRM2_MOUSE
NC score	0.096376 (rank : 76)	θ value	0.00665767 (rank : 62)
Query Neighborhood Hits	587	Target Neighborhood Hits	1470	Shared Neighborhood Hits	240
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

PCLO_HUMAN
NC score	0.094716 (rank : 77)	θ value	0.00390308 (rank : 58)
Query Neighborhood Hits	587	Target Neighborhood Hits	2046	Shared Neighborhood Hits	285
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SON_HUMAN
NC score	0.093324 (rank : 78)	θ value	θ > 10 (rank : 642)
Query Neighborhood Hits	587	Target Neighborhood Hits	1568	Shared Neighborhood Hits	318
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

KCNA1_MOUSE
NC score	0.092230 (rank : 79)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	587	Target Neighborhood Hits	103	Shared Neighborhood Hits	40
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

PCLO_MOUSE
NC score	0.091236 (rank : 80)	θ value	0.365318 (rank : 163)
Query Neighborhood Hits	587	Target Neighborhood Hits	2275	Shared Neighborhood Hits	345
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

MAGE1_HUMAN
NC score	0.090566 (rank : 81)	θ value	4.03905 (rank : 413)
Query Neighborhood Hits	587	Target Neighborhood Hits	1389	Shared Neighborhood Hits	318
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

SAPS1_HUMAN
NC score	0.090255 (rank : 82)	θ value	0.00509761 (rank : 60)
Query Neighborhood Hits	587	Target Neighborhood Hits	704	Shared Neighborhood Hits	237
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

ATN1_HUMAN
NC score	0.090155 (rank : 83)	θ value	5.44631e-05 (rank : 32)
Query Neighborhood Hits	587	Target Neighborhood Hits	676	Shared Neighborhood Hits	116
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

KCNA1_HUMAN
NC score	0.090039 (rank : 84)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	587	Target Neighborhood Hits	104	Shared Neighborhood Hits	39
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

K1802_MOUSE
NC score	0.089008 (rank : 85)	θ value	0.163984 (rank : 131)
Query Neighborhood Hits	587	Target Neighborhood Hits	1596	Shared Neighborhood Hits	266
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

KCNA2_MOUSE
NC score	0.088951 (rank : 86)	θ value	4.03905 (rank : 407)
Query Neighborhood Hits	587	Target Neighborhood Hits	102	Shared Neighborhood Hits	37
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNA2_HUMAN
NC score	0.087689 (rank : 87)	θ value	4.03905 (rank : 406)
Query Neighborhood Hits	587	Target Neighborhood Hits	101	Shared Neighborhood Hits	36
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

SRRM2_HUMAN
NC score	0.087412 (rank : 88)	θ value	0.00869519 (rank : 65)
Query Neighborhood Hits	587	Target Neighborhood Hits	1296	Shared Neighborhood Hits	199
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TARSH_HUMAN
NC score	0.087041 (rank : 89)	θ value	0.279714 (rank : 153)
Query Neighborhood Hits	587	Target Neighborhood Hits	768	Shared Neighborhood Hits	204
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

MDC1_MOUSE
NC score	0.086700 (rank : 90)	θ value	θ > 10 (rank : 626)
Query Neighborhood Hits	587	Target Neighborhood Hits	998	Shared Neighborhood Hits	215
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

DIDO1_HUMAN
NC score	0.086666 (rank : 91)	θ value	0.47712 (rank : 175)
Query Neighborhood Hits	587	Target Neighborhood Hits	960	Shared Neighborhood Hits	205
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

MLL3_HUMAN
NC score	0.086123 (rank : 92)	θ value	4.03905 (rank : 415)
Query Neighborhood Hits	587	Target Neighborhood Hits	1644	Shared Neighborhood Hits	280
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

GGN_HUMAN
NC score	0.085457 (rank : 93)	θ value	0.00020696 (rank : 39)
Query Neighborhood Hits	587	Target Neighborhood Hits	269	Shared Neighborhood Hits	67
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

KCNQ1_MOUSE
NC score	0.085180 (rank : 94)	θ value	5.27518 (rank : 460)
Query Neighborhood Hits	587	Target Neighborhood Hits	175	Shared Neighborhood Hits	65
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

SRRM1_HUMAN
NC score	0.084309 (rank : 95)	θ value	0.00175202 (rank : 55)
Query Neighborhood Hits	587	Target Neighborhood Hits	690	Shared Neighborhood Hits	114
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

YLPM1_HUMAN
NC score	0.084245 (rank : 96)	θ value	0.0736092 (rank : 110)
Query Neighborhood Hits	587	Target Neighborhood Hits	670	Shared Neighborhood Hits	146
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

WASIP_HUMAN
NC score	0.084084 (rank : 97)	θ value	0.0431538 (rank : 96)
Query Neighborhood Hits	587	Target Neighborhood Hits	458	Shared Neighborhood Hits	104
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

TARA_HUMAN
NC score	0.084059 (rank : 98)	θ value	0.0736092 (rank : 108)
Query Neighborhood Hits	587	Target Neighborhood Hits	1626	Shared Neighborhood Hits	257
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

PRP1_HUMAN
NC score	0.083908 (rank : 99)	θ value	0.0252991 (rank : 76)
Query Neighborhood Hits	587	Target Neighborhood Hits	385	Shared Neighborhood Hits	94
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

MLL3_MOUSE
NC score	0.083851 (rank : 100)	θ value	0.813845 (rank : 223)
Query Neighborhood Hits	587	Target Neighborhood Hits	1399	Shared Neighborhood Hits	243
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

KCNA6_MOUSE
NC score	0.083384 (rank : 101)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	587	Target Neighborhood Hits	106	Shared Neighborhood Hits	40
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNG1_HUMAN
NC score	0.082425 (rank : 102)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	587	Target Neighborhood Hits	103	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

NCOA6_MOUSE
NC score	0.081782 (rank : 103)	θ value	θ > 10 (rank : 632)
Query Neighborhood Hits	587	Target Neighborhood Hits	1076	Shared Neighborhood Hits	251
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

KCNQ4_HUMAN
NC score	0.081552 (rank : 104)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	587	Target Neighborhood Hits	136	Shared Neighborhood Hits	43
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

WASIP_MOUSE
NC score	0.080927 (rank : 105)	θ value	0.0961366 (rank : 123)
Query Neighborhood Hits	587	Target Neighborhood Hits	392	Shared Neighborhood Hits	100
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

KCNA6_HUMAN
NC score	0.080724 (rank : 106)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	587	Target Neighborhood Hits	100	Shared Neighborhood Hits	36
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNG2_HUMAN
NC score	0.080089 (rank : 107)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	587	Target Neighborhood Hits	83	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

MDC1_HUMAN
NC score	0.079979 (rank : 108)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	587	Target Neighborhood Hits	1446	Shared Neighborhood Hits	242
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

KCNA5_MOUSE
NC score	0.078769 (rank : 109)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	587	Target Neighborhood Hits	119	Shared Neighborhood Hits	37
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

GGN_MOUSE
NC score	0.078619 (rank : 110)	θ value	0.0736092 (rank : 104)
Query Neighborhood Hits	587	Target Neighborhood Hits	311	Shared Neighborhood Hits	73
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

KCNA3_HUMAN
NC score	0.078137 (rank : 111)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	587	Target Neighborhood Hits	101	Shared Neighborhood Hits	35
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

MINT_MOUSE
NC score	0.078072 (rank : 112)	θ value	0.00175202 (rank : 54)
Query Neighborhood Hits	587	Target Neighborhood Hits	1514	Shared Neighborhood Hits	242
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

RERE_MOUSE
NC score	0.077897 (rank : 113)	θ value	0.000786445 (rank : 48)
Query Neighborhood Hits	587	Target Neighborhood Hits	785	Shared Neighborhood Hits	126
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

BCL9_MOUSE
NC score	0.077842 (rank : 114)	θ value	2.36792 (rank : 317)
Query Neighborhood Hits	587	Target Neighborhood Hits	770	Shared Neighborhood Hits	213
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

KCNG4_HUMAN
NC score	0.077628 (rank : 115)	θ value	8.99809 (rank : 558)
Query Neighborhood Hits	587	Target Neighborhood Hits	99	Shared Neighborhood Hits	28
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

NFH_MOUSE
NC score	0.077125 (rank : 116)	θ value	0.47712 (rank : 181)
Query Neighborhood Hits	587	Target Neighborhood Hits	2247	Shared Neighborhood Hits	320
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

MILK1_MOUSE
NC score	0.077048 (rank : 117)	θ value	0.00035302 (rank : 42)
Query Neighborhood Hits	587	Target Neighborhood Hits	788	Shared Neighborhood Hits	201
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

BAT3_MOUSE
NC score	0.076939 (rank : 118)	θ value	0.0961366 (rank : 113)
Query Neighborhood Hits	587	Target Neighborhood Hits	518	Shared Neighborhood Hits	150
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

KCNA3_MOUSE
NC score	0.076194 (rank : 119)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	587	Target Neighborhood Hits	103	Shared Neighborhood Hits	33
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

YLPM1_MOUSE
NC score	0.075509 (rank : 120)	θ value	0.00390308 (rank : 59)
Query Neighborhood Hits	587	Target Neighborhood Hits	505	Shared Neighborhood Hits	93
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

MBD6_HUMAN
NC score	0.075016 (rank : 121)	θ value	0.00869519 (rank : 63)
Query Neighborhood Hits	587	Target Neighborhood Hits	349	Shared Neighborhood Hits	88
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

TCGAP_HUMAN
NC score	0.074779 (rank : 122)	θ value	0.813845 (rank : 232)
Query Neighborhood Hits	587	Target Neighborhood Hits	872	Shared Neighborhood Hits	225
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

GSCR1_HUMAN
NC score	0.074391 (rank : 123)	θ value	0.0330416 (rank : 80)
Query Neighborhood Hits	587	Target Neighborhood Hits	674	Shared Neighborhood Hits	140
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

SNPC4_HUMAN
NC score	0.074336 (rank : 124)	θ value	θ > 10 (rank : 641)
Query Neighborhood Hits	587	Target Neighborhood Hits	589	Shared Neighborhood Hits	188
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

KCNA5_HUMAN
NC score	0.074281 (rank : 125)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	587	Target Neighborhood Hits	124	Shared Neighborhood Hits	35
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

LCP2_HUMAN
NC score	0.073437 (rank : 126)	θ value	8.99809 (rank : 560)
Query Neighborhood Hits	587	Target Neighborhood Hits	531	Shared Neighborhood Hits	157
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

BAT3_HUMAN
NC score	0.073399 (rank : 127)	θ value	0.813845 (rank : 208)
Query Neighborhood Hits	587	Target Neighborhood Hits	490	Shared Neighborhood Hits	154
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

RGS3_HUMAN
NC score	0.073323 (rank : 128)	θ value	θ > 10 (rank : 637)
Query Neighborhood Hits	587	Target Neighborhood Hits	1375	Shared Neighborhood Hits	300
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

TGON2_HUMAN
NC score	0.073057 (rank : 129)	θ value	θ > 10 (rank : 649)
Query Neighborhood Hits	587	Target Neighborhood Hits	1037	Shared Neighborhood Hits	178
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

PKDRE_MOUSE
NC score	0.072104 (rank : 130)	θ value	8.99809 (rank : 570)
Query Neighborhood Hits	587	Target Neighborhood Hits	76	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

PRP2_MOUSE
NC score	0.071273 (rank : 131)	θ value	0.0148317 (rank : 69)
Query Neighborhood Hits	587	Target Neighborhood Hits	347	Shared Neighborhood Hits	74
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

CD2_HUMAN
NC score	0.071054 (rank : 132)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	587	Target Neighborhood Hits	504	Shared Neighborhood Hits	156
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

KCNQ1_HUMAN
NC score	0.070960 (rank : 133)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	587	Target Neighborhood Hits	99	Shared Neighborhood Hits	37
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

SSBP4_HUMAN
NC score	0.070943 (rank : 134)	θ value	θ > 10 (rank : 644)
Query Neighborhood Hits	587	Target Neighborhood Hits	753	Shared Neighborhood Hits	238
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

KCNQ5_HUMAN
NC score	0.070823 (rank : 135)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	587	Target Neighborhood Hits	163	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

GRIN1_HUMAN
NC score	0.069973 (rank : 136)	θ value	1.81305 (rank : 291)
Query Neighborhood Hits	587	Target Neighborhood Hits	681	Shared Neighborhood Hits	174
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

PI5PA_HUMAN
NC score	0.069885 (rank : 137)	θ value	0.813845 (rank : 226)
Query Neighborhood Hits	587	Target Neighborhood Hits	749	Shared Neighborhood Hits	215
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

FA47A_HUMAN
NC score	0.069623 (rank : 138)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	587	Target Neighborhood Hits	451	Shared Neighborhood Hits	136
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

SELPL_MOUSE
NC score	0.069303 (rank : 139)	θ value	θ > 10 (rank : 640)
Query Neighborhood Hits	587	Target Neighborhood Hits	588	Shared Neighborhood Hits	156
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SC24C_HUMAN
NC score	0.069009 (rank : 140)	θ value	θ > 10 (rank : 639)
Query Neighborhood Hits	587	Target Neighborhood Hits	662	Shared Neighborhood Hits	211
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

PRB4S_HUMAN
NC score	0.068174 (rank : 141)	θ value	0.365318 (rank : 166)
Query Neighborhood Hits	587	Target Neighborhood Hits	330	Shared Neighborhood Hits	79
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

MUC7_HUMAN
NC score	0.068064 (rank : 142)	θ value	0.125558 (rank : 127)
Query Neighborhood Hits	587	Target Neighborhood Hits	538	Shared Neighborhood Hits	101
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

SGIP1_MOUSE
NC score	0.067520 (rank : 143)	θ value	0.0148317 (rank : 70)
Query Neighborhood Hits	587	Target Neighborhood Hits	180	Shared Neighborhood Hits	49
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

RAPH1_HUMAN
NC score	0.066736 (rank : 144)	θ value	0.000270298 (rank : 40)
Query Neighborhood Hits	587	Target Neighborhood Hits	593	Shared Neighborhood Hits	116
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

FA47B_HUMAN
NC score	0.066671 (rank : 145)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	587	Target Neighborhood Hits	431	Shared Neighborhood Hits	139
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

RERE_HUMAN
NC score	0.066379 (rank : 146)	θ value	0.0330416 (rank : 87)
Query Neighborhood Hits	587	Target Neighborhood Hits	779	Shared Neighborhood Hits	129
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

ARI1A_HUMAN
NC score	0.066000 (rank : 147)	θ value	0.813845 (rank : 207)
Query Neighborhood Hits	587	Target Neighborhood Hits	787	Shared Neighborhood Hits	165
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

MLL4_HUMAN
NC score	0.065834 (rank : 148)	θ value	5.44631e-05 (rank : 33)
Query Neighborhood Hits	587	Target Neighborhood Hits	722	Shared Neighborhood Hits	132
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

KCNA4_MOUSE
NC score	0.065699 (rank : 149)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	587	Target Neighborhood Hits	98	Shared Neighborhood Hits	29
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

IWS1_MOUSE
NC score	0.065543 (rank : 150)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	587	Target Neighborhood Hits	1258	Shared Neighborhood Hits	175
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

KCNA4_HUMAN
NC score	0.065310 (rank : 151)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	587	Target Neighborhood Hits	108	Shared Neighborhood Hits	29
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

MLL2_HUMAN
NC score	0.064420 (rank : 152)	θ value	0.0563607 (rank : 97)
Query Neighborhood Hits	587	Target Neighborhood Hits	1788	Shared Neighborhood Hits	245
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

SGIP1_HUMAN
NC score	0.064216 (rank : 153)	θ value	0.0330416 (rank : 88)
Query Neighborhood Hits	587	Target Neighborhood Hits	198	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

CO039_MOUSE
NC score	0.064133 (rank : 154)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	587	Target Neighborhood Hits	445	Shared Neighborhood Hits	145
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

SON_MOUSE
NC score	0.064046 (rank : 155)	θ value	0.62314 (rank : 205)
Query Neighborhood Hits	587	Target Neighborhood Hits	957	Shared Neighborhood Hits	191
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

CEL_HUMAN
NC score	0.063844 (rank : 156)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	587	Target Neighborhood Hits	896	Shared Neighborhood Hits	231
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

BAG3_MOUSE
NC score	0.063751 (rank : 157)	θ value	8.99809 (rank : 534)
Query Neighborhood Hits	587	Target Neighborhood Hits	513	Shared Neighborhood Hits	160
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

SFPQ_HUMAN
NC score	0.063221 (rank : 158)	θ value	0.000121331 (rank : 36)
Query Neighborhood Hits	587	Target Neighborhood Hits	986	Shared Neighborhood Hits	126
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

PHC2_HUMAN
NC score	0.063140 (rank : 159)	θ value	0.0431538 (rank : 92)
Query Neighborhood Hits	587	Target Neighborhood Hits	388	Shared Neighborhood Hits	126
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

KCNQ3_HUMAN
NC score	0.062308 (rank : 160)	θ value	0.62314 (rank : 195)
Query Neighborhood Hits	587	Target Neighborhood Hits	114	Shared Neighborhood Hits	37
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

TAF4_HUMAN
NC score	0.062161 (rank : 161)	θ value	θ > 10 (rank : 646)
Query Neighborhood Hits	587	Target Neighborhood Hits	687	Shared Neighborhood Hits	125
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

PRR12_HUMAN
NC score	0.061710 (rank : 162)	θ value	0.0736092 (rank : 107)
Query Neighborhood Hits	587	Target Neighborhood Hits	460	Shared Neighborhood Hits	88
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

CBP_MOUSE
NC score	0.061686 (rank : 163)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	587	Target Neighborhood Hits	1051	Shared Neighborhood Hits	209
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

MISS_MOUSE
NC score	0.061529 (rank : 164)	θ value	θ > 10 (rank : 627)
Query Neighborhood Hits	587	Target Neighborhood Hits	444	Shared Neighborhood Hits	143
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

K1802_HUMAN
NC score	0.061438 (rank : 165)	θ value	0.00175202 (rank : 53)
Query Neighborhood Hits	587	Target Neighborhood Hits	1378	Shared Neighborhood Hits	212
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

KCNQ3_MOUSE
NC score	0.061321 (rank : 166)	θ value	0.62314 (rank : 196)
Query Neighborhood Hits	587	Target Neighborhood Hits	105	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

CS016_HUMAN
NC score	0.061318 (rank : 167)	θ value	0.125558 (rank : 124)
Query Neighborhood Hits	587	Target Neighborhood Hits	310	Shared Neighborhood Hits	76
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

CIC_HUMAN
NC score	0.060994 (rank : 168)	θ value	2.36792 (rank : 321)
Query Neighborhood Hits	587	Target Neighborhood Hits	992	Shared Neighborhood Hits	230
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CBP_HUMAN
NC score	0.060607 (rank : 169)	θ value	5.27518 (rank : 440)
Query Neighborhood Hits	587	Target Neighborhood Hits	941	Shared Neighborhood Hits	195
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

NPBL_MOUSE
NC score	0.060418 (rank : 170)	θ value	θ > 10 (rank : 634)
Query Neighborhood Hits	587	Target Neighborhood Hits	1041	Shared Neighborhood Hits	157
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

SYN1_HUMAN
NC score	0.060240 (rank : 171)	θ value	0.125558 (rank : 129)
Query Neighborhood Hits	587	Target Neighborhood Hits	419	Shared Neighborhood Hits	98
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

PSL1_HUMAN
NC score	0.060144 (rank : 172)	θ value	θ > 10 (rank : 636)
Query Neighborhood Hits	587	Target Neighborhood Hits	650	Shared Neighborhood Hits	202
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

MKL1_MOUSE
NC score	0.060052 (rank : 173)	θ value	θ > 10 (rank : 628)
Query Neighborhood Hits	587	Target Neighborhood Hits	667	Shared Neighborhood Hits	193
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

MCLN2_MOUSE
NC score	0.060051 (rank : 174)	θ value	1.38821 (rank : 267)
Query Neighborhood Hits	587	Target Neighborhood Hits	31	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K595, Q3UCG4, Q8K2T6, Q9CQD3	Gene names	Mcoln2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

ENAH_MOUSE
NC score	0.059946 (rank : 175)	θ value	0.0148317 (rank : 68)
Query Neighborhood Hits	587	Target Neighborhood Hits	919	Shared Neighborhood Hits	121
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

ZIMP7_MOUSE
NC score	0.059699 (rank : 176)	θ value	0.62314 (rank : 206)
Query Neighborhood Hits	587	Target Neighborhood Hits	566	Shared Neighborhood Hits	171
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

EP300_HUMAN
NC score	0.059622 (rank : 177)	θ value	0.279714 (rank : 148)
Query Neighborhood Hits	587	Target Neighborhood Hits	821	Shared Neighborhood Hits	169
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

LPP_HUMAN
NC score	0.059585 (rank : 178)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	587	Target Neighborhood Hits	775	Shared Neighborhood Hits	219
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

TRPV3_HUMAN
NC score	0.059553 (rank : 179)	θ value	8.99809 (rank : 582)
Query Neighborhood Hits	587	Target Neighborhood Hits	198	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TAB3_MOUSE
NC score	0.058694 (rank : 180)	θ value	0.0563607 (rank : 100)
Query Neighborhood Hits	587	Target Neighborhood Hits	273	Shared Neighborhood Hits	75
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

MTSS1_MOUSE
NC score	0.058325 (rank : 181)	θ value	8.99809 (rank : 565)
Query Neighborhood Hits	587	Target Neighborhood Hits	592	Shared Neighborhood Hits	168
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

ALEX_HUMAN
NC score	0.058300 (rank : 182)	θ value	1.81305 (rank : 280)
Query Neighborhood Hits	587	Target Neighborhood Hits	361	Shared Neighborhood Hits	98
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ZN385_HUMAN
NC score	0.058051 (rank : 183)	θ value	θ > 10 (rank : 652)
Query Neighborhood Hits	587	Target Neighborhood Hits	614	Shared Neighborhood Hits	181
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

RUSC2_MOUSE
NC score	0.058030 (rank : 184)	θ value	0.21417 (rank : 142)
Query Neighborhood Hits	587	Target Neighborhood Hits	305	Shared Neighborhood Hits	88
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

ARI1B_HUMAN
NC score	0.057846 (rank : 185)	θ value	3.0926 (rank : 354)
Query Neighborhood Hits	587	Target Neighborhood Hits	567	Shared Neighborhood Hits	147
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

WIRE_MOUSE
NC score	0.057530 (rank : 186)	θ value	0.21417 (rank : 147)
Query Neighborhood Hits	587	Target Neighborhood Hits	310	Shared Neighborhood Hits	76
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

KCNQ2_HUMAN
NC score	0.057448 (rank : 187)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	587	Target Neighborhood Hits	114	Shared Neighborhood Hits	41
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

CSF1_HUMAN
NC score	0.057422 (rank : 188)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	587	Target Neighborhood Hits	258	Shared Neighborhood Hits	108
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

TXND2_HUMAN
NC score	0.057229 (rank : 189)	θ value	θ > 10 (rank : 651)
Query Neighborhood Hits	587	Target Neighborhood Hits	793	Shared Neighborhood Hits	138
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

KCNQ2_MOUSE
NC score	0.057023 (rank : 190)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	587	Target Neighborhood Hits	163	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

DOT1L_HUMAN
NC score	0.056570 (rank : 191)	θ value	1.38821 (rank : 260)
Query Neighborhood Hits	587	Target Neighborhood Hits	660	Shared Neighborhood Hits	129
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

WBP11_MOUSE
NC score	0.055885 (rank : 192)	θ value	0.21417 (rank : 146)
Query Neighborhood Hits	587	Target Neighborhood Hits	362	Shared Neighborhood Hits	74
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

CT151_HUMAN
NC score	0.055397 (rank : 193)	θ value	0.0252991 (rank : 75)
Query Neighborhood Hits	587	Target Neighborhood Hits	382	Shared Neighborhood Hits	68
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

NIPBL_HUMAN
NC score	0.055389 (rank : 194)	θ value	θ > 10 (rank : 633)
Query Neighborhood Hits	587	Target Neighborhood Hits	1311	Shared Neighborhood Hits	170
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

MBB1A_HUMAN
NC score	0.055281 (rank : 195)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	587	Target Neighborhood Hits	665	Shared Neighborhood Hits	164
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

IRS2_MOUSE
NC score	0.055229 (rank : 196)	θ value	0.00665767 (rank : 61)
Query Neighborhood Hits	587	Target Neighborhood Hits	248	Shared Neighborhood Hits	61
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

WBP11_HUMAN
NC score	0.055173 (rank : 197)	θ value	0.21417 (rank : 145)
Query Neighborhood Hits	587	Target Neighborhood Hits	354	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

PRB3_HUMAN
NC score	0.055147 (rank : 198)	θ value	4.03905 (rank : 423)
Query Neighborhood Hits	587	Target Neighborhood Hits	318	Shared Neighborhood Hits	77
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

CK024_HUMAN
NC score	0.055032 (rank : 199)	θ value	θ > 10 (rank : 593)
Query Neighborhood Hits	587	Target Neighborhood Hits	408	Shared Neighborhood Hits	127
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

IQEC3_MOUSE
NC score	0.054853 (rank : 200)	θ value	0.000461057 (rank : 44)
Query Neighborhood Hits	587	Target Neighborhood Hits	274	Shared Neighborhood Hits	71
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

AFF1_HUMAN
NC score	0.054573 (rank : 201)	θ value	0.365318 (rank : 157)
Query Neighborhood Hits	587	Target Neighborhood Hits	506	Shared Neighborhood Hits	88
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

SFPQ_MOUSE
NC score	0.054548 (rank : 202)	θ value	0.21417 (rank : 143)
Query Neighborhood Hits	587	Target Neighborhood Hits	958	Shared Neighborhood Hits	111
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

PDZD2_HUMAN
NC score	0.054530 (rank : 203)	θ value	0.62314 (rank : 201)
Query Neighborhood Hits	587	Target Neighborhood Hits	772	Shared Neighborhood Hits	160
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

SPR1B_MOUSE
NC score	0.054314 (rank : 204)	θ value	θ > 10 (rank : 643)
Query Neighborhood Hits	587	Target Neighborhood Hits	395	Shared Neighborhood Hits	137
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

ZIM10_HUMAN
NC score	0.054045 (rank : 205)	θ value	5.27518 (rank : 488)
Query Neighborhood Hits	587	Target Neighborhood Hits	577	Shared Neighborhood Hits	171
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

MUCDL_HUMAN
NC score	0.053724 (rank : 206)	θ value	θ > 10 (rank : 630)
Query Neighborhood Hits	587	Target Neighborhood Hits	777	Shared Neighborhood Hits	194
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

SMR1_MOUSE
NC score	0.053535 (rank : 207)	θ value	0.21417 (rank : 144)
Query Neighborhood Hits	587	Target Neighborhood Hits	103	Shared Neighborhood Hits	26
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

ATX2L_HUMAN
NC score	0.053470 (rank : 208)	θ value	0.0736092 (rank : 102)
Query Neighborhood Hits	587	Target Neighborhood Hits	443	Shared Neighborhood Hits	104
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

CECR2_HUMAN
NC score	0.053073 (rank : 209)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	587	Target Neighborhood Hits	543	Shared Neighborhood Hits	169
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

GA2L2_MOUSE
NC score	0.052587 (rank : 210)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	587	Target Neighborhood Hits	395	Shared Neighborhood Hits	139
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

T22D4_HUMAN
NC score	0.052562 (rank : 211)	θ value	θ > 10 (rank : 645)
Query Neighborhood Hits	587	Target Neighborhood Hits	403	Shared Neighborhood Hits	144
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

TP53B_MOUSE
NC score	0.052020 (rank : 212)	θ value	θ > 10 (rank : 650)
Query Neighborhood Hits	587	Target Neighborhood Hits	644	Shared Neighborhood Hits	122
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

MARCS_HUMAN
NC score	0.051973 (rank : 213)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	587	Target Neighborhood Hits	204	Shared Neighborhood Hits	37
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

TARA_MOUSE
NC score	0.051725 (rank : 214)	θ value	θ > 10 (rank : 647)
Query Neighborhood Hits	587	Target Neighborhood Hits	1133	Shared Neighborhood Hits	144
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TAU_MOUSE
NC score	0.051442 (rank : 215)	θ value	θ > 10 (rank : 648)
Query Neighborhood Hits	587	Target Neighborhood Hits	502	Shared Neighborhood Hits	129
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

PK1L1_HUMAN
NC score	0.051110 (rank : 216)	θ value	0.62314 (rank : 202)
Query Neighborhood Hits	587	Target Neighborhood Hits	140	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

CABIN_HUMAN
NC score	0.050959 (rank : 217)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	587	Target Neighborhood Hits	490	Shared Neighborhood Hits	134
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

ATX7_MOUSE
NC score	0.050557 (rank : 218)	θ value	4.03905 (rank : 390)
Query Neighborhood Hits	587	Target Neighborhood Hits	328	Shared Neighborhood Hits	117
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

MILK1_HUMAN
NC score	0.050330 (rank : 219)	θ value	0.00298849 (rank : 56)
Query Neighborhood Hits	587	Target Neighborhood Hits	427	Shared Neighborhood Hits	78
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

SYN1_MOUSE
NC score	0.050301 (rank : 220)	θ value	1.38821 (rank : 273)
Query Neighborhood Hits	587	Target Neighborhood Hits	363	Shared Neighborhood Hits	80
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

IASPP_MOUSE
NC score	0.050299 (rank : 221)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	587	Target Neighborhood Hits	1024	Shared Neighborhood Hits	216
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IRS2_HUMAN
NC score	0.050184 (rank : 222)	θ value	0.0961366 (rank : 117)
Query Neighborhood Hits	587	Target Neighborhood Hits	262	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

MN1_HUMAN
NC score	0.049877 (rank : 223)	θ value	0.0563607 (rank : 98)
Query Neighborhood Hits	587	Target Neighborhood Hits	196	Shared Neighborhood Hits	45
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

CPSF6_MOUSE
NC score	0.049756 (rank : 224)	θ value	1.81305 (rank : 285)
Query Neighborhood Hits	587	Target Neighborhood Hits	356	Shared Neighborhood Hits	83
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CJ078_MOUSE
NC score	0.049291 (rank : 225)	θ value	6.88961 (rank : 495)
Query Neighborhood Hits	587	Target Neighborhood Hits	559	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

BRD4_MOUSE
NC score	0.048533 (rank : 226)	θ value	0.000786445 (rank : 47)
Query Neighborhood Hits	587	Target Neighborhood Hits	845	Shared Neighborhood Hits	109
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CO002_HUMAN
NC score	0.048316 (rank : 227)	θ value	4.03905 (rank : 392)
Query Neighborhood Hits	587	Target Neighborhood Hits	387	Shared Neighborhood Hits	101
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

NCOR2_HUMAN
NC score	0.047273 (rank : 228)	θ value	0.813845 (rank : 224)
Query Neighborhood Hits	587	Target Neighborhood Hits	870	Shared Neighborhood Hits	130
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

MINT_HUMAN
NC score	0.046943 (rank : 229)	θ value	1.38821 (rank : 268)
Query Neighborhood Hits	587	Target Neighborhood Hits	1291	Shared Neighborhood Hits	153
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

CPSF6_HUMAN
NC score	0.046909 (rank : 230)	θ value	1.81305 (rank : 284)
Query Neighborhood Hits	587	Target Neighborhood Hits	359	Shared Neighborhood Hits	83
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

ATX2_MOUSE
NC score	0.046262 (rank : 231)	θ value	6.88961 (rank : 493)
Query Neighborhood Hits	587	Target Neighborhood Hits	445	Shared Neighborhood Hits	113
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

SYNJ1_MOUSE
NC score	0.045884 (rank : 232)	θ value	0.813845 (rank : 231)
Query Neighborhood Hits	587	Target Neighborhood Hits	516	Shared Neighborhood Hits	127
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

CIC_MOUSE
NC score	0.045525 (rank : 233)	θ value	3.0926 (rank : 356)
Query Neighborhood Hits	587	Target Neighborhood Hits	742	Shared Neighborhood Hits	157
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

TNC6B_HUMAN
NC score	0.045434 (rank : 234)	θ value	0.0113563 (rank : 66)
Query Neighborhood Hits	587	Target Neighborhood Hits	256	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

IQEC2_MOUSE
NC score	0.044859 (rank : 235)	θ value	0.0961366 (rank : 115)
Query Neighborhood Hits	587	Target Neighborhood Hits	417	Shared Neighborhood Hits	69
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_HUMAN
NC score	0.044272 (rank : 236)	θ value	0.0961366 (rank : 114)
Query Neighborhood Hits	587	Target Neighborhood Hits	403	Shared Neighborhood Hits	69
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

SMOO_HUMAN
NC score	0.044077 (rank : 237)	θ value	0.47712 (rank : 184)
Query Neighborhood Hits	587	Target Neighborhood Hits	391	Shared Neighborhood Hits	87
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

RP1L1_HUMAN
NC score	0.043784 (rank : 238)	θ value	0.0252991 (rank : 77)
Query Neighborhood Hits	587	Target Neighborhood Hits	1072	Shared Neighborhood Hits	155
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

MAP1A_HUMAN
NC score	0.043686 (rank : 239)	θ value	6.88961 (rank : 511)
Query Neighborhood Hits	587	Target Neighborhood Hits	1626	Shared Neighborhood Hits	215
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

GRIN1_MOUSE
NC score	0.043361 (rank : 240)	θ value	5.27518 (rank : 452)
Query Neighborhood Hits	587	Target Neighborhood Hits	337	Shared Neighborhood Hits	92
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

HRX_HUMAN
NC score	0.043081 (rank : 241)	θ value	1.06291 (rank : 242)
Query Neighborhood Hits	587	Target Neighborhood Hits	825	Shared Neighborhood Hits	108
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

HCN4_HUMAN
NC score	0.042849 (rank : 242)	θ value	0.000461057 (rank : 43)
Query Neighborhood Hits	587	Target Neighborhood Hits	303	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

PDC6I_HUMAN
NC score	0.042467 (rank : 243)	θ value	0.813845 (rank : 225)
Query Neighborhood Hits	587	Target Neighborhood Hits	278	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

AUTS2_HUMAN
NC score	0.042069 (rank : 244)	θ value	0.62314 (rank : 189)
Query Neighborhood Hits	587	Target Neighborhood Hits	342	Shared Neighborhood Hits	66
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

BAZ2A_MOUSE
NC score	0.041869 (rank : 245)	θ value	3.0926 (rank : 355)
Query Neighborhood Hits	587	Target Neighborhood Hits	744	Shared Neighborhood Hits	151
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

CI079_HUMAN
NC score	0.041846 (rank : 246)	θ value	6.88961 (rank : 494)
Query Neighborhood Hits	587	Target Neighborhood Hits	288	Shared Neighborhood Hits	84
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

AFF1_MOUSE
NC score	0.041797 (rank : 247)	θ value	0.0736092 (rank : 101)
Query Neighborhood Hits	587	Target Neighborhood Hits	351	Shared Neighborhood Hits	54
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

ALEX_MOUSE
NC score	0.041664 (rank : 248)	θ value	1.81305 (rank : 281)
Query Neighborhood Hits	587	Target Neighborhood Hits	197	Shared Neighborhood Hits	54
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

PCQAP_MOUSE
NC score	0.041131 (rank : 249)	θ value	0.365318 (rank : 164)
Query Neighborhood Hits	587	Target Neighborhood Hits	506	Shared Neighborhood Hits	79
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

PPRB_MOUSE
NC score	0.040895 (rank : 250)	θ value	1.81305 (rank : 302)
Query Neighborhood Hits	587	Target Neighborhood Hits	354	Shared Neighborhood Hits	77
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

SFRIP_HUMAN
NC score	0.040741 (rank : 251)	θ value	6.88961 (rank : 521)
Query Neighborhood Hits	587	Target Neighborhood Hits	530	Shared Neighborhood Hits	76
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

MAP4_MOUSE
NC score	0.040111 (rank : 252)	θ value	2.36792 (rank : 338)
Query Neighborhood Hits	587	Target Neighborhood Hits	409	Shared Neighborhood Hits	83
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

PPRB_HUMAN
NC score	0.039907 (rank : 253)	θ value	0.47712 (rank : 182)
Query Neighborhood Hits	587	Target Neighborhood Hits	311	Shared Neighborhood Hits	62
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

SYN3_HUMAN
NC score	0.039890 (rank : 254)	θ value	2.36792 (rank : 344)
Query Neighborhood Hits	587	Target Neighborhood Hits	203	Shared Neighborhood Hits	55
SwissProt Accessions	O14994	Gene names	SYN3
Domain Architecture
Description	Synapsin-3 (Synapsin III).

BRD4_HUMAN
NC score	0.039826 (rank : 255)	θ value	0.813845 (rank : 209)
Query Neighborhood Hits	587	Target Neighborhood Hits	851	Shared Neighborhood Hits	113
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

PRGC2_HUMAN
NC score	0.039443 (rank : 256)	θ value	1.06291 (rank : 249)
Query Neighborhood Hits	587	Target Neighborhood Hits	272	Shared Neighborhood Hits	65
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

TAB3_HUMAN
NC score	0.039132 (rank : 257)	θ value	0.163984 (rank : 135)
Query Neighborhood Hits	587	Target Neighborhood Hits	168	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

LEUK_HUMAN
NC score	0.039083 (rank : 258)	θ value	5.27518 (rank : 461)
Query Neighborhood Hits	587	Target Neighborhood Hits	213	Shared Neighborhood Hits	50
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

CO039_HUMAN
NC score	0.039074 (rank : 259)	θ value	4.03905 (rank : 393)
Query Neighborhood Hits	587	Target Neighborhood Hits	264	Shared Neighborhood Hits	86
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

TM131_MOUSE
NC score	0.039063 (rank : 260)	θ value	0.279714 (rank : 154)
Query Neighborhood Hits	587	Target Neighborhood Hits	156	Shared Neighborhood Hits	29
SwissProt Accessions	O70472	Gene names	Tmem131, D1Bwg0491e, Rw1
Domain Architecture	No domain graphic available
Description	Transmembrane protein 131 (Protein RW1).

PHLB1_HUMAN
NC score	0.039023 (rank : 261)	θ value	8.99809 (rank : 569)
Query Neighborhood Hits	587	Target Neighborhood Hits	1038	Shared Neighborhood Hits	154
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

FMN1A_MOUSE
NC score	0.038879 (rank : 262)	θ value	0.813845 (rank : 218)
Query Neighborhood Hits	587	Target Neighborhood Hits	423	Shared Neighborhood Hits	73
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

ANK2_HUMAN
NC score	0.038572 (rank : 263)	θ value	6.88961 (rank : 490)
Query Neighborhood Hits	587	Target Neighborhood Hits	1615	Shared Neighborhood Hits	252
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

K1949_MOUSE
NC score	0.038437 (rank : 264)	θ value	0.0330416 (rank : 81)
Query Neighborhood Hits	587	Target Neighborhood Hits	134	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BQ30, Q3UDS6, Q8CEY9, Q8R3D8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1949 homolog.

SYNJ1_HUMAN
NC score	0.038183 (rank : 265)	θ value	1.38821 (rank : 274)
Query Neighborhood Hits	587	Target Neighborhood Hits	498	Shared Neighborhood Hits	121
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

HCN4_MOUSE
NC score	0.038139 (rank : 266)	θ value	0.365318 (rank : 160)
Query Neighborhood Hits	587	Target Neighborhood Hits	284	Shared Neighborhood Hits	61
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

SYNPO_HUMAN
NC score	0.037547 (rank : 267)	θ value	6.88961 (rank : 525)
Query Neighborhood Hits	587	Target Neighborhood Hits	281	Shared Neighborhood Hits	81
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

WASL_HUMAN
NC score	0.037390 (rank : 268)	θ value	4.03905 (rank : 432)
Query Neighborhood Hits	587	Target Neighborhood Hits	312	Shared Neighborhood Hits	74
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

RUSC2_HUMAN
NC score	0.037166 (rank : 269)	θ value	0.47712 (rank : 183)
Query Neighborhood Hits	587	Target Neighborhood Hits	205	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

CNOT3_MOUSE
NC score	0.037155 (rank : 270)	θ value	1.38821 (rank : 256)
Query Neighborhood Hits	587	Target Neighborhood Hits	504	Shared Neighborhood Hits	72
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

IQEC3_HUMAN
NC score	0.037014 (rank : 271)	θ value	0.0961366 (rank : 116)
Query Neighborhood Hits	587	Target Neighborhood Hits	125	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

CSKI1_MOUSE
NC score	0.036967 (rank : 272)	θ value	0.163984 (rank : 130)
Query Neighborhood Hits	587	Target Neighborhood Hits	1031	Shared Neighborhood Hits	203
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

SNIP_MOUSE
NC score	0.036910 (rank : 273)	θ value	0.365318 (rank : 169)
Query Neighborhood Hits	587	Target Neighborhood Hits	319	Shared Neighborhood Hits	58
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

WASL_MOUSE
NC score	0.036904 (rank : 274)	θ value	5.27518 (rank : 485)
Query Neighborhood Hits	587	Target Neighborhood Hits	339	Shared Neighborhood Hits	72
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

GNAS1_MOUSE
NC score	0.036826 (rank : 275)	θ value	5.27518 (rank : 451)
Query Neighborhood Hits	587	Target Neighborhood Hits	651	Shared Neighborhood Hits	176
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

CS007_HUMAN
NC score	0.036760 (rank : 276)	θ value	2.36792 (rank : 324)
Query Neighborhood Hits	587	Target Neighborhood Hits	401	Shared Neighborhood Hits	91
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

NOLC1_HUMAN
NC score	0.036634 (rank : 277)	θ value	1.06291 (rank : 246)
Query Neighborhood Hits	587	Target Neighborhood Hits	452	Shared Neighborhood Hits	63
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

FILA_HUMAN
NC score	0.036502 (rank : 278)	θ value	1.06291 (rank : 239)
Query Neighborhood Hits	587	Target Neighborhood Hits	685	Shared Neighborhood Hits	68
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

PRPC_HUMAN
NC score	0.036257 (rank : 279)	θ value	6.88961 (rank : 517)
Query Neighborhood Hits	587	Target Neighborhood Hits	165	Shared Neighborhood Hits	42
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

TB182_HUMAN
NC score	0.036037 (rank : 280)	θ value	5.27518 (rank : 481)
Query Neighborhood Hits	587	Target Neighborhood Hits	414	Shared Neighborhood Hits	80
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

PI5PA_MOUSE
NC score	0.035935 (rank : 281)	θ value	4.03905 (rank : 419)
Query Neighborhood Hits	587	Target Neighborhood Hits	331	Shared Neighborhood Hits	84
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

AKAP2_MOUSE
NC score	0.035854 (rank : 282)	θ value	0.62314 (rank : 187)
Query Neighborhood Hits	587	Target Neighborhood Hits	385	Shared Neighborhood Hits	63
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

ZDHC8_MOUSE
NC score	0.035762 (rank : 283)	θ value	0.0193708 (rank : 73)
Query Neighborhood Hits	587	Target Neighborhood Hits	243	Shared Neighborhood Hits	71
SwissProt Accessions	Q5Y5T5, Q7TNF7	Gene names	Zdhhc8
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8).

FMN2_HUMAN
NC score	0.035564 (rank : 284)	θ value	0.21417 (rank : 138)
Query Neighborhood Hits	587	Target Neighborhood Hits	484	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

PDC6I_MOUSE
NC score	0.035547 (rank : 285)	θ value	1.38821 (rank : 270)
Query Neighborhood Hits	587	Target Neighborhood Hits	275	Shared Neighborhood Hits	48
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

LEUK_MOUSE
NC score	0.035455 (rank : 286)	θ value	0.813845 (rank : 221)
Query Neighborhood Hits	587	Target Neighborhood Hits	147	Shared Neighborhood Hits	34
SwissProt Accessions	P15702	Gene names	Spn
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Ly- 48) (B cell differentiation antigen LP-3) (CD43 antigen).

3BP1_HUMAN
NC score	0.034762 (rank : 287)	θ value	0.0961366 (rank : 111)
Query Neighborhood Hits	587	Target Neighborhood Hits	376	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

REXO1_HUMAN
NC score	0.034613 (rank : 288)	θ value	0.813845 (rank : 228)
Query Neighborhood Hits	587	Target Neighborhood Hits	242	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

WASF2_MOUSE
NC score	0.034608 (rank : 289)	θ value	1.81305 (rank : 314)
Query Neighborhood Hits	587	Target Neighborhood Hits	315	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

ASPP1_MOUSE
NC score	0.034505 (rank : 290)	θ value	4.03905 (rank : 389)
Query Neighborhood Hits	587	Target Neighborhood Hits	1244	Shared Neighborhood Hits	181
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

RIN3_MOUSE
NC score	0.034247 (rank : 291)	θ value	0.0961366 (rank : 120)
Query Neighborhood Hits	587	Target Neighborhood Hits	239	Shared Neighborhood Hits	51
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

INP5E_HUMAN
NC score	0.034242 (rank : 292)	θ value	2.36792 (rank : 331)
Query Neighborhood Hits	587	Target Neighborhood Hits	201	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

LSR_MOUSE
NC score	0.034003 (rank : 293)	θ value	0.21417 (rank : 141)
Query Neighborhood Hits	587	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q99KG5, Q3TJE7, Q3UIQ9, Q61148, Q61149, Q6U816	Gene names	Lsr, Lisch7
Domain Architecture	No domain graphic available
Description	Lipolysis-stimulated lipoprotein receptor precursor (Liver-specific bHLH-Zip transcription factor) (Lipolysis-stimulated receptor) (Liver- specific gene on mouse chromosome 7 protein).

ELL_HUMAN
NC score	0.033927 (rank : 294)	θ value	0.0736092 (rank : 103)
Query Neighborhood Hits	587	Target Neighborhood Hits	183	Shared Neighborhood Hits	54
SwissProt Accessions	P55199	Gene names	ELL, C19orf17
Domain Architecture
Description	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein).

CNOT3_HUMAN
NC score	0.033613 (rank : 295)	θ value	2.36792 (rank : 323)
Query Neighborhood Hits	587	Target Neighborhood Hits	425	Shared Neighborhood Hits	58
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

LSR_HUMAN
NC score	0.033549 (rank : 296)	θ value	0.21417 (rank : 140)
Query Neighborhood Hits	587	Target Neighborhood Hits	45	Shared Neighborhood Hits	8
SwissProt Accessions	Q86X29, O00112, O00426, Q6ZT80, Q9UQL3	Gene names	LSR, LISCH
Domain Architecture	No domain graphic available
Description	Lipolysis-stimulated lipoprotein receptor.

COHA1_MOUSE
NC score	0.033273 (rank : 297)	θ value	0.813845 (rank : 212)
Query Neighborhood Hits	587	Target Neighborhood Hits	414	Shared Neighborhood Hits	85
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

WASP_HUMAN
NC score	0.033201 (rank : 298)	θ value	1.06291 (rank : 252)
Query Neighborhood Hits	587	Target Neighborhood Hits	195	Shared Neighborhood Hits	55
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

HCN2_HUMAN
NC score	0.033117 (rank : 299)	θ value	4.03905 (rank : 404)
Query Neighborhood Hits	587	Target Neighborhood Hits	369	Shared Neighborhood Hits	95
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

SHAN2_MOUSE
NC score	0.033074 (rank : 300)	θ value	0.365318 (rank : 168)
Query Neighborhood Hits	587	Target Neighborhood Hits	446	Shared Neighborhood Hits	61
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SYN3_MOUSE
NC score	0.032978 (rank : 301)	θ value	5.27518 (rank : 478)
Query Neighborhood Hits	587	Target Neighborhood Hits	200	Shared Neighborhood Hits	50
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

RPTN_MOUSE
NC score	0.032667 (rank : 302)	θ value	6.88961 (rank : 520)
Query Neighborhood Hits	587	Target Neighborhood Hits	650	Shared Neighborhood Hits	84
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

SYP2L_HUMAN
NC score	0.032618 (rank : 303)	θ value	5.27518 (rank : 479)
Query Neighborhood Hits	587	Target Neighborhood Hits	400	Shared Neighborhood Hits	93
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

SYN2_HUMAN
NC score	0.032432 (rank : 304)	θ value	6.88961 (rank : 524)
Query Neighborhood Hits	587	Target Neighborhood Hits	213	Shared Neighborhood Hits	53
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

SNIP_HUMAN
NC score	0.032414 (rank : 305)	θ value	1.81305 (rank : 307)
Query Neighborhood Hits	587	Target Neighborhood Hits	313	Shared Neighborhood Hits	55
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

RP3A_MOUSE
NC score	0.032277 (rank : 306)	θ value	6.88961 (rank : 519)
Query Neighborhood Hits	587	Target Neighborhood Hits	510	Shared Neighborhood Hits	139
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

NIBL_HUMAN
NC score	0.031556 (rank : 307)	θ value	0.125558 (rank : 128)
Query Neighborhood Hits	587	Target Neighborhood Hits	61	Shared Neighborhood Hits	17
SwissProt Accessions	Q96TA1, Q9BUS2, Q9NT35	Gene names	C9orf88
Domain Architecture	No domain graphic available
Description	Niban-like protein (Meg-3).

SF01_HUMAN
NC score	0.031228 (rank : 308)	θ value	0.62314 (rank : 204)
Query Neighborhood Hits	587	Target Neighborhood Hits	287	Shared Neighborhood Hits	58
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

ACINU_HUMAN
NC score	0.031050 (rank : 309)	θ value	6.88961 (rank : 489)
Query Neighborhood Hits	587	Target Neighborhood Hits	828	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

CPSF7_MOUSE
NC score	0.031049 (rank : 310)	θ value	1.06291 (rank : 237)
Query Neighborhood Hits	587	Target Neighborhood Hits	123	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BTV2, Q3TNF1, Q8BKE7, Q8CFS8	Gene names	Cpsf7
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 7.

FBX46_MOUSE
NC score	0.030974 (rank : 311)	θ value	1.38821 (rank : 261)
Query Neighborhood Hits	587	Target Neighborhood Hits	139	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BG80	Gene names	Fbxo46, Fbx46, Fbxo34l
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

CO2A1_HUMAN
NC score	0.030629 (rank : 312)	θ value	1.06291 (rank : 236)
Query Neighborhood Hits	587	Target Neighborhood Hits	486	Shared Neighborhood Hits	113
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

PTN23_HUMAN
NC score	0.030444 (rank : 313)	θ value	0.00869519 (rank : 64)
Query Neighborhood Hits	587	Target Neighborhood Hits	646	Shared Neighborhood Hits	90
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

CPSF7_HUMAN
NC score	0.030429 (rank : 314)	θ value	1.38821 (rank : 258)
Query Neighborhood Hits	587	Target Neighborhood Hits	125	Shared Neighborhood Hits	27
SwissProt Accessions	Q8N684, Q7Z3H9, Q9H025, Q9H9V1	Gene names	CPSF7
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 7 (Cleavage and polyadenylation specificity factor 59 kDa subunit) (CPSF 59 kDa subunit) (Pre-mRNA cleavage factor Im 59 kDa subunit).

CO5A1_HUMAN
NC score	0.030425 (rank : 315)	θ value	8.99809 (rank : 540)
Query Neighborhood Hits	587	Target Neighborhood Hits	434	Shared Neighborhood Hits	91
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

WASP_MOUSE
NC score	0.030069 (rank : 316)	θ value	5.27518 (rank : 486)
Query Neighborhood Hits	587	Target Neighborhood Hits	223	Shared Neighborhood Hits	60
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

WASF4_HUMAN
NC score	0.030048 (rank : 317)	θ value	5.27518 (rank : 484)
Query Neighborhood Hits	587	Target Neighborhood Hits	282	Shared Neighborhood Hits	71
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

ZDHC8_HUMAN
NC score	0.029930 (rank : 318)	θ value	0.365318 (rank : 170)
Query Neighborhood Hits	587	Target Neighborhood Hits	234	Shared Neighborhood Hits	74
SwissProt Accessions	Q9ULC8, Q6ICL1, Q6ZNF5, Q7Z6L9	Gene names	ZDHHC8, KIAA1292, ZDHHCL1, ZNF378
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8) (Zinc finger protein 378).

SF3B4_HUMAN
NC score	0.029840 (rank : 319)	θ value	4.03905 (rank : 427)
Query Neighborhood Hits	587	Target Neighborhood Hits	445	Shared Neighborhood Hits	66
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

SHAN1_HUMAN
NC score	0.029709 (rank : 320)	θ value	0.279714 (rank : 152)
Query Neighborhood Hits	587	Target Neighborhood Hits	1041	Shared Neighborhood Hits	131
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

COIA1_HUMAN
NC score	0.029680 (rank : 321)	θ value	1.38821 (rank : 257)
Query Neighborhood Hits	587	Target Neighborhood Hits	447	Shared Neighborhood Hits	105
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

VASP_HUMAN
NC score	0.029671 (rank : 322)	θ value	5.27518 (rank : 482)
Query Neighborhood Hits	587	Target Neighborhood Hits	201	Shared Neighborhood Hits	50
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

CO4A4_HUMAN
NC score	0.029658 (rank : 323)	θ value	3.0926 (rank : 359)
Query Neighborhood Hits	587	Target Neighborhood Hits	440	Shared Neighborhood Hits	98
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

PHLB1_MOUSE
NC score	0.029633 (rank : 324)	θ value	2.36792 (rank : 340)
Query Neighborhood Hits	587	Target Neighborhood Hits	678	Shared Neighborhood Hits	84
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PTN23_MOUSE
NC score	0.029603 (rank : 325)	θ value	3.0926 (rank : 380)
Query Neighborhood Hits	587	Target Neighborhood Hits	726	Shared Neighborhood Hits	114
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

CO1A1_MOUSE
NC score	0.029526 (rank : 326)	θ value	3.0926 (rank : 357)
Query Neighborhood Hits	587	Target Neighborhood Hits	457	Shared Neighborhood Hits	88
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

HCN2_MOUSE
NC score	0.029464 (rank : 327)	θ value	0.813845 (rank : 220)
Query Neighborhood Hits	587	Target Neighborhood Hits	278	Shared Neighborhood Hits	67
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

FMN1B_MOUSE
NC score	0.029399 (rank : 328)	θ value	5.27518 (rank : 448)
Query Neighborhood Hits	587	Target Neighborhood Hits	447	Shared Neighborhood Hits	78
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

JIP2_HUMAN
NC score	0.029208 (rank : 329)	θ value	2.36792 (rank : 335)
Query Neighborhood Hits	587	Target Neighborhood Hits	288	Shared Neighborhood Hits	82
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

EP400_MOUSE
NC score	0.028582 (rank : 330)	θ value	0.813845 (rank : 216)
Query Neighborhood Hits	587	Target Neighborhood Hits	592	Shared Neighborhood Hits	116
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

STRC_MOUSE
NC score	0.028156 (rank : 331)	θ value	0.0961366 (rank : 121)
Query Neighborhood Hits	587	Target Neighborhood Hits	89	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VIM6	Gene names	Strc
Domain Architecture	No domain graphic available
Description	Stereocilin precursor.

TCGAP_MOUSE
NC score	0.027700 (rank : 332)	θ value	0.163984 (rank : 136)
Query Neighborhood Hits	587	Target Neighborhood Hits	409	Shared Neighborhood Hits	70
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

CSKI2_HUMAN
NC score	0.027654 (rank : 333)	θ value	0.125558 (rank : 125)
Query Neighborhood Hits	587	Target Neighborhood Hits	747	Shared Neighborhood Hits	100
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

VASP_MOUSE
NC score	0.027559 (rank : 334)	θ value	5.27518 (rank : 483)
Query Neighborhood Hits	587	Target Neighborhood Hits	195	Shared Neighborhood Hits	42
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

IL3RB_HUMAN
NC score	0.027497 (rank : 335)	θ value	0.279714 (rank : 149)
Query Neighborhood Hits	587	Target Neighborhood Hits	163	Shared Neighborhood Hits	36
SwissProt Accessions	P32927	Gene names	CSF2RB, IL3RB, IL5RB
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen) (CDw131).

CO3A1_HUMAN
NC score	0.027478 (rank : 336)	θ value	8.99809 (rank : 539)
Query Neighborhood Hits	587	Target Neighborhood Hits	452	Shared Neighborhood Hits	91
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

FMNL_HUMAN
NC score	0.027462 (rank : 337)	θ value	4.03905 (rank : 400)
Query Neighborhood Hits	587	Target Neighborhood Hits	529	Shared Neighborhood Hits	83
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

PDCD7_MOUSE
NC score	0.027263 (rank : 338)	θ value	1.81305 (rank : 301)
Query Neighborhood Hits	587	Target Neighborhood Hits	214	Shared Neighborhood Hits	28
SwissProt Accessions	Q9WTY1, Q8R5D9	Gene names	Pdcd7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18).

BCOR_HUMAN
NC score	0.027113 (rank : 339)	θ value	1.06291 (rank : 234)
Query Neighborhood Hits	587	Target Neighborhood Hits	609	Shared Neighborhood Hits	87
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

PRR11_HUMAN
NC score	0.027045 (rank : 340)	θ value	0.62314 (rank : 203)
Query Neighborhood Hits	587	Target Neighborhood Hits	27	Shared Neighborhood Hits	13
SwissProt Accessions	Q96HE9, Q9NUZ7, Q9NXE9	Gene names	PRR11
Domain Architecture	No domain graphic available
Description	Proline-rich protein 11.

CSKI2_MOUSE
NC score	0.027018 (rank : 341)	θ value	1.81305 (rank : 286)
Query Neighborhood Hits	587	Target Neighborhood Hits	812	Shared Neighborhood Hits	148
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

PRAX_HUMAN
NC score	0.027014 (rank : 342)	θ value	6.88961 (rank : 516)
Query Neighborhood Hits	587	Target Neighborhood Hits	215	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

MUCDL_MOUSE
NC score	0.026632 (rank : 343)	θ value	0.365318 (rank : 162)
Query Neighborhood Hits	587	Target Neighborhood Hits	461	Shared Neighborhood Hits	79
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

DGKK_HUMAN
NC score	0.026608 (rank : 344)	θ value	3.0926 (rank : 363)
Query Neighborhood Hits	587	Target Neighborhood Hits	378	Shared Neighborhood Hits	63
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

EFS_HUMAN
NC score	0.026576 (rank : 345)	θ value	4.03905 (rank : 397)
Query Neighborhood Hits	587	Target Neighborhood Hits	348	Shared Neighborhood Hits	74
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

BCAS1_MOUSE
NC score	0.026400 (rank : 346)	θ value	2.36792 (rank : 316)
Query Neighborhood Hits	587	Target Neighborhood Hits	215	Shared Neighborhood Hits	42
SwissProt Accessions	Q80YN3, Q9CVA1	Gene names	Bcas1, Nabc1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 homolog (Novel amplified in breast cancer 1 homolog).

BRDT_MOUSE
NC score	0.026336 (rank : 347)	θ value	0.62314 (rank : 190)
Query Neighborhood Hits	587	Target Neighborhood Hits	243	Shared Neighborhood Hits	26
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

HGS_MOUSE
NC score	0.026329 (rank : 348)	θ value	1.81305 (rank : 292)
Query Neighborhood Hits	587	Target Neighborhood Hits	589	Shared Neighborhood Hits	95
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

CK021_HUMAN
NC score	0.026178 (rank : 349)	θ value	2.36792 (rank : 322)
Query Neighborhood Hits	587	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P2W6	Gene names	C11orf21
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf21.

ZC3H3_MOUSE
NC score	0.026166 (rank : 350)	θ value	2.36792 (rank : 350)
Query Neighborhood Hits	587	Target Neighborhood Hits	188	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

MUC13_MOUSE
NC score	0.026082 (rank : 351)	θ value	5.27518 (rank : 466)
Query Neighborhood Hits	587	Target Neighborhood Hits	447	Shared Neighborhood Hits	54
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

WASF3_HUMAN
NC score	0.025990 (rank : 352)	θ value	6.88961 (rank : 529)
Query Neighborhood Hits	587	Target Neighborhood Hits	204	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

SYP2L_MOUSE
NC score	0.025757 (rank : 353)	θ value	1.81305 (rank : 308)
Query Neighborhood Hits	587	Target Neighborhood Hits	289	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

PDCD7_HUMAN
NC score	0.025756 (rank : 354)	θ value	4.03905 (rank : 418)
Query Neighborhood Hits	587	Target Neighborhood Hits	255	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

CT055_HUMAN
NC score	0.025589 (rank : 355)	θ value	0.813845 (rank : 213)
Query Neighborhood Hits	587	Target Neighborhood Hits	42	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BQ89	Gene names	C20orf55
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf55.

CO2A1_MOUSE
NC score	0.025587 (rank : 356)	θ value	3.0926 (rank : 358)
Query Neighborhood Hits	587	Target Neighborhood Hits	483	Shared Neighborhood Hits	95
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

PSD4_HUMAN
NC score	0.025429 (rank : 357)	θ value	4.03905 (rank : 424)
Query Neighborhood Hits	587	Target Neighborhood Hits	178	Shared Neighborhood Hits	44
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

MKL1_HUMAN
NC score	0.025232 (rank : 358)	θ value	0.813845 (rank : 222)
Query Neighborhood Hits	587	Target Neighborhood Hits	232	Shared Neighborhood Hits	37
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

MUC2_HUMAN
NC score	0.025171 (rank : 359)	θ value	5.27518 (rank : 467)
Query Neighborhood Hits	587	Target Neighborhood Hits	906	Shared Neighborhood Hits	97
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MAST4_HUMAN
NC score	0.025040 (rank : 360)	θ value	0.0961366 (rank : 118)
Query Neighborhood Hits	587	Target Neighborhood Hits	1804	Shared Neighborhood Hits	242
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

ABI2_HUMAN
NC score	0.024909 (rank : 361)	θ value	0.0961366 (rank : 112)
Query Neighborhood Hits	587	Target Neighborhood Hits	350	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

PRGC2_MOUSE
NC score	0.024861 (rank : 362)	θ value	5.27518 (rank : 471)
Query Neighborhood Hits	587	Target Neighborhood Hits	225	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

WBS14_HUMAN
NC score	0.024782 (rank : 363)	θ value	5.27518 (rank : 487)
Query Neighborhood Hits	587	Target Neighborhood Hits	273	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

MCLN3_HUMAN
NC score	0.024313 (rank : 364)	θ value	8.99809 (rank : 562)
Query Neighborhood Hits	587	Target Neighborhood Hits	26	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TDD5, Q5T4H5, Q5T4H6, Q9NV09	Gene names	MCOLN3
Domain Architecture	No domain graphic available
Description	Mucolipin-3.

TREF1_HUMAN
NC score	0.024036 (rank : 365)	θ value	1.81305 (rank : 311)
Query Neighborhood Hits	587	Target Neighborhood Hits	651	Shared Neighborhood Hits	57
SwissProt Accessions	Q96PN7, Q7Z6T2, Q7Z6T3, Q9NQ72, Q9NQ73, Q9NUN9	Gene names	TRERF1, RAPA, TREP132
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132) (Zinc finger protein rapa).

SMCA4_HUMAN
NC score	0.023973 (rank : 366)	θ value	0.0563607 (rank : 99)
Query Neighborhood Hits	587	Target Neighborhood Hits	597	Shared Neighborhood Hits	85
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

IRX5_MOUSE
NC score	0.023721 (rank : 367)	θ value	0.21417 (rank : 139)
Query Neighborhood Hits	587	Target Neighborhood Hits	324	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JKQ4, Q80WV4, Q9JLL5	Gene names	Irx5, Irxb2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2).

3BP1_MOUSE
NC score	0.023720 (rank : 368)	θ value	4.03905 (rank : 388)
Query Neighborhood Hits	587	Target Neighborhood Hits	238	Shared Neighborhood Hits	42
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

LSD1_HUMAN
NC score	0.023715 (rank : 369)	θ value	3.0926 (rank : 375)
Query Neighborhood Hits	587	Target Neighborhood Hits	455	Shared Neighborhood Hits	93
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

ZCPW1_MOUSE
NC score	0.023319 (rank : 370)	θ value	4.03905 (rank : 433)
Query Neighborhood Hits	587	Target Neighborhood Hits	307	Shared Neighborhood Hits	48
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

ZYX_HUMAN
NC score	0.023230 (rank : 371)	θ value	0.279714 (rank : 156)
Query Neighborhood Hits	587	Target Neighborhood Hits	387	Shared Neighborhood Hits	56
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

WASF3_MOUSE
NC score	0.023148 (rank : 372)	θ value	8.99809 (rank : 584)
Query Neighborhood Hits	587	Target Neighborhood Hits	188	Shared Neighborhood Hits	51
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

UBP42_HUMAN
NC score	0.023076 (rank : 373)	θ value	1.38821 (rank : 276)
Query Neighborhood Hits	587	Target Neighborhood Hits	445	Shared Neighborhood Hits	90
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

HSF1_HUMAN
NC score	0.023002 (rank : 374)	θ value	3.0926 (rank : 368)
Query Neighborhood Hits	587	Target Neighborhood Hits	163	Shared Neighborhood Hits	46
SwissProt Accessions	Q00613	Gene names	HSF1, HSTF1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

ACD_HUMAN
NC score	0.022860 (rank : 375)	θ value	5.27518 (rank : 435)
Query Neighborhood Hits	587	Target Neighborhood Hits	143	Shared Neighborhood Hits	35
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

FOG1_MOUSE
NC score	0.022840 (rank : 376)	θ value	3.0926 (rank : 365)
Query Neighborhood Hits	587	Target Neighborhood Hits	1237	Shared Neighborhood Hits	179
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

CO7A1_HUMAN
NC score	0.022784 (rank : 377)	θ value	5.27518 (rank : 443)
Query Neighborhood Hits	587	Target Neighborhood Hits	807	Shared Neighborhood Hits	121
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CO4A5_HUMAN
NC score	0.022760 (rank : 378)	θ value	6.88961 (rank : 496)
Query Neighborhood Hits	587	Target Neighborhood Hits	383	Shared Neighborhood Hits	81
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

R3HD1_HUMAN
NC score	0.022674 (rank : 379)	θ value	4.03905 (rank : 425)
Query Neighborhood Hits	587	Target Neighborhood Hits	203	Shared Neighborhood Hits	39
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

F8I2_HUMAN
NC score	0.022452 (rank : 380)	θ value	0.813845 (rank : 217)
Query Neighborhood Hits	587	Target Neighborhood Hits	17	Shared Neighborhood Hits	5
SwissProt Accessions	P23610, Q8IXP3	Gene names	F8A1, F8A
Domain Architecture	No domain graphic available
Description	Factor VIII intron 22 protein (CpG island protein).

YTHD2_HUMAN
NC score	0.022429 (rank : 381)	θ value	0.279714 (rank : 155)
Query Neighborhood Hits	587	Target Neighborhood Hits	89	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y5A9, Q5VSZ9, Q8TDH0, Q9BUJ5	Gene names	YTHDF2, HGRG8
Domain Architecture
Description	YTH domain family protein 2 (High-glucose-regulated protein 8) (NY- REN-2 antigen) (CLL-associated antigen KW-14).

EP400_HUMAN
NC score	0.022352 (rank : 382)	θ value	6.88961 (rank : 499)
Query Neighborhood Hits	587	Target Neighborhood Hits	556	Shared Neighborhood Hits	93
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

BCOR_MOUSE
NC score	0.022272 (rank : 383)	θ value	1.81305 (rank : 283)
Query Neighborhood Hits	587	Target Neighborhood Hits	521	Shared Neighborhood Hits	71
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CD008_HUMAN
NC score	0.022030 (rank : 384)	θ value	8.99809 (rank : 536)
Query Neighborhood Hits	587	Target Neighborhood Hits	330	Shared Neighborhood Hits	49
SwissProt Accessions	P78312, O43607, P78311, P78313, Q9UEG8	Gene names	C4orf8
Domain Architecture	No domain graphic available
Description	Protein C4orf8 (Protein IT14).

TRPM2_MOUSE
NC score	0.021783 (rank : 385)	θ value	0.813845 (rank : 233)
Query Neighborhood Hits	587	Target Neighborhood Hits	61	Shared Neighborhood Hits	11
SwissProt Accessions	Q91YD4	Gene names	Trpm2, Ltrpc2, Trpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7).

ZC3H3_HUMAN
NC score	0.021780 (rank : 386)	θ value	8.99809 (rank : 586)
Query Neighborhood Hits	587	Target Neighborhood Hits	159	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IXZ2, Q14163, Q8N4E2, Q9BUS4	Gene names	ZC3H3, KIAA0150, ZC3HDC3
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

NIBL_MOUSE
NC score	0.021757 (rank : 387)	θ value	3.0926 (rank : 377)
Query Neighborhood Hits	587	Target Neighborhood Hits	54	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R1F1	Gene names
Domain Architecture	No domain graphic available
Description	Niban-like protein.

PO6F2_HUMAN
NC score	0.021699 (rank : 388)	θ value	2.36792 (rank : 341)
Query Neighborhood Hits	587	Target Neighborhood Hits	618	Shared Neighborhood Hits	81
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

DLGP3_HUMAN
NC score	0.021582 (rank : 389)	θ value	0.365318 (rank : 158)
Query Neighborhood Hits	587	Target Neighborhood Hits	55	Shared Neighborhood Hits	13
SwissProt Accessions	O95886, Q5TDD5, Q9H3X7	Gene names	DLGAP3, DAP3
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 3 (DAP-3) (SAP90/PSD-95-associated protein 3) (SAPAP3) (PSD-95/SAP90-binding protein 3).

GCX1_HUMAN
NC score	0.021556 (rank : 390)	θ value	1.38821 (rank : 262)
Query Neighborhood Hits	587	Target Neighborhood Hits	132	Shared Neighborhood Hits	22
SwissProt Accessions	Q96NM4, Q5TE33, Q5TE34, Q5TE35, Q96IC9, Q9BQN5	Gene names	GCX1, C20orf100
Domain Architecture
Description	Granulosa cell HMG box protein 1 (GCX-1).

SRCA_HUMAN
NC score	0.021427 (rank : 391)	θ value	3.0926 (rank : 384)
Query Neighborhood Hits	587	Target Neighborhood Hits	380	Shared Neighborhood Hits	56
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

INVS_MOUSE
NC score	0.021295 (rank : 392)	θ value	6.88961 (rank : 506)
Query Neighborhood Hits	587	Target Neighborhood Hits	609	Shared Neighborhood Hits	121
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

AATK_HUMAN
NC score	0.021136 (rank : 393)	θ value	0.21417 (rank : 137)
Query Neighborhood Hits	587	Target Neighborhood Hits	1243	Shared Neighborhood Hits	185
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

K0355_HUMAN
NC score	0.021023 (rank : 394)	θ value	3.0926 (rank : 370)
Query Neighborhood Hits	587	Target Neighborhood Hits	55	Shared Neighborhood Hits	11
SwissProt Accessions	O15063	Gene names	KIAA0355
Domain Architecture	No domain graphic available
Description	Protein KIAA0355.

K0141_MOUSE
NC score	0.020975 (rank : 395)	θ value	0.62314 (rank : 192)
Query Neighborhood Hits	587	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DCV6, Q6A0B8	Gene names	Kiaa0141
Domain Architecture
Description	Protein KIAA0141.

COFA1_HUMAN
NC score	0.020852 (rank : 396)	θ value	6.88961 (rank : 497)
Query Neighborhood Hits	587	Target Neighborhood Hits	292	Shared Neighborhood Hits	64
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

CEP72_HUMAN
NC score	0.020746 (rank : 397)	θ value	2.36792 (rank : 319)
Query Neighborhood Hits	587	Target Neighborhood Hits	374	Shared Neighborhood Hits	27
SwissProt Accessions	Q9P209, Q9BV03, Q9BWM3, Q9NVR4	Gene names	CEP72, KIAA1519
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

DEN1A_HUMAN
NC score	0.020691 (rank : 398)	θ value	1.06291 (rank : 238)
Query Neighborhood Hits	587	Target Neighborhood Hits	176	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

SNPC4_MOUSE
NC score	0.020675 (rank : 399)	θ value	5.27518 (rank : 474)
Query Neighborhood Hits	587	Target Neighborhood Hits	237	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

SMRC1_MOUSE
NC score	0.020665 (rank : 400)	θ value	3.0926 (rank : 383)
Query Neighborhood Hits	587	Target Neighborhood Hits	459	Shared Neighborhood Hits	55
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

SMRC1_HUMAN
NC score	0.020577 (rank : 401)	θ value	1.06291 (rank : 251)
Query Neighborhood Hits	587	Target Neighborhood Hits	375	Shared Neighborhood Hits	50
SwissProt Accessions	Q92922, Q6P172, Q8IWH2	Gene names	SMARCC1, BAF155
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155).

CMTA2_MOUSE
NC score	0.020570 (rank : 402)	θ value	1.06291 (rank : 235)
Query Neighborhood Hits	587	Target Neighborhood Hits	216	Shared Neighborhood Hits	31
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

HXA3_MOUSE
NC score	0.020466 (rank : 403)	θ value	0.0431538 (rank : 89)
Query Neighborhood Hits	587	Target Neighborhood Hits	558	Shared Neighborhood Hits	72
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

IRX1_HUMAN
NC score	0.020447 (rank : 404)	θ value	0.125558 (rank : 126)
Query Neighborhood Hits	587	Target Neighborhood Hits	285	Shared Neighborhood Hits	25
SwissProt Accessions	P78414, Q7Z2F8, Q8N312	Gene names	IRX1, IRXA1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-1 (Iroquois homeobox protein 1) (Homeodomain protein IRXA1).

SREC2_HUMAN
NC score	0.020443 (rank : 405)	θ value	0.0193708 (rank : 72)
Query Neighborhood Hits	587	Target Neighborhood Hits	645	Shared Neighborhood Hits	52
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

LNP_MOUSE
NC score	0.020404 (rank : 406)	θ value	3.0926 (rank : 373)
Query Neighborhood Hits	587	Target Neighborhood Hits	83	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TQ95, Q69ZC5, Q6PAQ1, Q6PEN8	Gene names	Lnp, Kiaa1715, Uln
Domain Architecture	No domain graphic available
Description	Protein lunapark (Protein ulnaless).

PP1RA_MOUSE
NC score	0.020293 (rank : 407)	θ value	6.88961 (rank : 515)
Query Neighborhood Hits	587	Target Neighborhood Hits	175	Shared Neighborhood Hits	35
SwissProt Accessions	Q80W00, Q811B6, Q8C6T7, Q8K2U8	Gene names	Ppp1r10, Cat53
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 1 regulatory subunit 10 (MHC class I region proline-rich protein CAT53).

RBM12_HUMAN
NC score	0.020197 (rank : 408)	θ value	1.81305 (rank : 304)
Query Neighborhood Hits	587	Target Neighborhood Hits	298	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

PKHA4_HUMAN
NC score	0.020147 (rank : 409)	θ value	4.03905 (rank : 420)
Query Neighborhood Hits	587	Target Neighborhood Hits	283	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

DLGP3_MOUSE
NC score	0.019770 (rank : 410)	θ value	0.813845 (rank : 215)
Query Neighborhood Hits	587	Target Neighborhood Hits	56	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PFD5, Q6PDX0, Q6XBF2	Gene names	Dlgap3, Dap3
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 3 (DAP-3) (SAP90/PSD-95-associated protein 3) (SAPAP3) (PSD-95/SAP90-binding protein 3).

JARD2_MOUSE
NC score	0.019682 (rank : 411)	θ value	2.36792 (rank : 333)
Query Neighborhood Hits	587	Target Neighborhood Hits	169	Shared Neighborhood Hits	33
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

COFA1_MOUSE
NC score	0.019609 (rank : 412)	θ value	3.0926 (rank : 360)
Query Neighborhood Hits	587	Target Neighborhood Hits	305	Shared Neighborhood Hits	67
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

JARD2_HUMAN
NC score	0.019448 (rank : 413)	θ value	2.36792 (rank : 332)
Query Neighborhood Hits	587	Target Neighborhood Hits	119	Shared Neighborhood Hits	25
SwissProt Accessions	Q92833, Q5U5L5	Gene names	JARID2, JMJ
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

PHC3_HUMAN
NC score	0.019201 (rank : 414)	θ value	6.88961 (rank : 514)
Query Neighborhood Hits	587	Target Neighborhood Hits	218	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NDX5, Q5HYF0, Q6NSG2, Q8NFT7, Q8NFZ1, Q8TBM2, Q9H971, Q9H9I4	Gene names	PHC3, EDR3, PH3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3 (hPH3) (Homolog of polyhomeotic 3) (Early development regulatory protein 3).

C8AP2_MOUSE
NC score	0.019166 (rank : 415)	θ value	0.813845 (rank : 210)
Query Neighborhood Hits	587	Target Neighborhood Hits	405	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

FBX46_HUMAN
NC score	0.019069 (rank : 416)	θ value	2.36792 (rank : 326)
Query Neighborhood Hits	587	Target Neighborhood Hits	68	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PJ61	Gene names	FBXO46, FBX46, FBXO34L
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

PACS1_HUMAN
NC score	0.018956 (rank : 417)	θ value	4.03905 (rank : 416)
Query Neighborhood Hits	587	Target Neighborhood Hits	82	Shared Neighborhood Hits	18
SwissProt Accessions	Q6VY07, Q6PJY6, Q6PKB6, Q7Z590, Q7Z5W4, Q8N8K6, Q96MW0, Q9NW92, Q9ULP5	Gene names	PACS1, KIAA1175
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

HXA3_HUMAN
NC score	0.018918 (rank : 418)	θ value	0.47712 (rank : 178)
Query Neighborhood Hits	587	Target Neighborhood Hits	535	Shared Neighborhood Hits	65
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

ZO1_MOUSE
NC score	0.018911 (rank : 419)	θ value	0.365318 (rank : 172)
Query Neighborhood Hits	587	Target Neighborhood Hits	453	Shared Neighborhood Hits	65
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ASTN_MOUSE
NC score	0.018835 (rank : 420)	θ value	0.62314 (rank : 188)
Query Neighborhood Hits	587	Target Neighborhood Hits	98	Shared Neighborhood Hits	4
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

PLXB1_MOUSE
NC score	0.018588 (rank : 421)	θ value	0.0330416 (rank : 86)
Query Neighborhood Hits	587	Target Neighborhood Hits	259	Shared Neighborhood Hits	66
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

EMID2_HUMAN
NC score	0.018568 (rank : 422)	θ value	5.27518 (rank : 446)
Query Neighborhood Hits	587	Target Neighborhood Hits	226	Shared Neighborhood Hits	51
SwissProt Accessions	Q96A83	Gene names	EMID2, COL26A1, EMU2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

CHSS3_HUMAN
NC score	0.018503 (rank : 423)	θ value	0.813845 (rank : 211)
Query Neighborhood Hits	587	Target Neighborhood Hits	97	Shared Neighborhood Hits	12
SwissProt Accessions	Q70JA7, Q76L22, Q86Y52	Gene names	CSS3, CHSY2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 3 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase II) (Chondroitin synthase 2) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II) (Carbohydrate synthase 2).

TAF3_MOUSE
NC score	0.018487 (rank : 424)	θ value	5.27518 (rank : 480)
Query Neighborhood Hits	587	Target Neighborhood Hits	463	Shared Neighborhood Hits	42
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

RGP2_HUMAN
NC score	0.018434 (rank : 425)	θ value	0.365318 (rank : 167)
Query Neighborhood Hits	587	Target Neighborhood Hits	60	Shared Neighborhood Hits	10
SwissProt Accessions	P47736	Gene names	RAP1GAP, RAP1GA1
Domain Architecture
Description	Rap1 GTPase-activating protein 1 (Rap1GAP).

ZN516_MOUSE
NC score	0.018312 (rank : 426)	θ value	1.38821 (rank : 277)
Query Neighborhood Hits	587	Target Neighborhood Hits	1197	Shared Neighborhood Hits	185
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

F120C_MOUSE
NC score	0.018275 (rank : 427)	θ value	4.03905 (rank : 398)
Query Neighborhood Hits	587	Target Neighborhood Hits	98	Shared Neighborhood Hits	35
SwissProt Accessions	Q8C3F2	Gene names	Fam120c, ORF34
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120C.

CCD95_HUMAN
NC score	0.018181 (rank : 428)	θ value	5.27518 (rank : 441)
Query Neighborhood Hits	587	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NBZ0	Gene names	CCDC95
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 95.

CSTFT_MOUSE
NC score	0.018081 (rank : 429)	θ value	5.27518 (rank : 444)
Query Neighborhood Hits	587	Target Neighborhood Hits	356	Shared Neighborhood Hits	56
SwissProt Accessions	Q8C7E9, Q6A016, Q8BHH7, Q8C3W7, Q8R2Y1, Q9EPU3	Gene names	Cstf2t, Kiaa0689
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit, tau variant (CSTF 64 kDa subunit, tau variant) (CF-1 64 kDa subunit, tau variant) (TauCstF-64).

LNP_HUMAN
NC score	0.017998 (rank : 430)	θ value	4.03905 (rank : 411)
Query Neighborhood Hits	587	Target Neighborhood Hits	62	Shared Neighborhood Hits	11
SwissProt Accessions	Q9C0E8, Q2M2V8, Q2YD99, Q658W8, Q8N5V9, Q96MS5	Gene names	LNP, KIAA1715
Domain Architecture	No domain graphic available
Description	Protein lunapark.

NAT6_HUMAN
NC score	0.017902 (rank : 431)	θ value	1.81305 (rank : 297)
Query Neighborhood Hits	587	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q93015, Q93014	Gene names	NAT6, FUS2
Domain Architecture
Description	N-acetyltransferase 6 (EC 2.3.1.-) (Fus-2 protein) (Fusion 2 protein).

GFC1_HUMAN
NC score	0.017385 (rank : 432)	θ value	4.03905 (rank : 402)
Query Neighborhood Hits	587	Target Neighborhood Hits	95	Shared Neighborhood Hits	20
SwissProt Accessions	P63117	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)1_Xq21.33 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein].

IF4G1_HUMAN
NC score	0.017354 (rank : 433)	θ value	6.88961 (rank : 505)
Query Neighborhood Hits	587	Target Neighborhood Hits	347	Shared Neighborhood Hits	69
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

GA2L3_HUMAN
NC score	0.017271 (rank : 434)	θ value	6.88961 (rank : 503)
Query Neighborhood Hits	587	Target Neighborhood Hits	189	Shared Neighborhood Hits	42
SwissProt Accessions	Q86XJ1	Gene names	GAS2L3
Domain Architecture	No domain graphic available
Description	GAS2-like protein 3 (Growth arrest-specific 2-like 3).

EMID1_HUMAN
NC score	0.017114 (rank : 435)	θ value	8.99809 (rank : 548)
Query Neighborhood Hits	587	Target Neighborhood Hits	215	Shared Neighborhood Hits	51
SwissProt Accessions	Q96A84, Q6ICG1, Q86SS7	Gene names	EMID1, EMU1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

SREC2_MOUSE
NC score	0.016845 (rank : 436)	θ value	3.0926 (rank : 385)
Query Neighborhood Hits	587	Target Neighborhood Hits	605	Shared Neighborhood Hits	51
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

PER1_HUMAN
NC score	0.016832 (rank : 437)	θ value	1.38821 (rank : 271)
Query Neighborhood Hits	587	Target Neighborhood Hits	215	Shared Neighborhood Hits	45
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

ZDHC5_HUMAN
NC score	0.016780 (rank : 438)	θ value	3.0926 (rank : 387)
Query Neighborhood Hits	587	Target Neighborhood Hits	106	Shared Neighborhood Hits	16
SwissProt Accessions	Q9C0B5, Q6ZMF0, Q8TAK8, Q9H923, Q9UFI7	Gene names	ZDHHC5, KIAA1748, ZNF375
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC5 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 5) (DHHC-5) (Zinc finger protein 375).

RP3A_HUMAN
NC score	0.016446 (rank : 439)	θ value	4.03905 (rank : 426)
Query Neighborhood Hits	587	Target Neighborhood Hits	305	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

OSTP_MOUSE
NC score	0.016295 (rank : 440)	θ value	1.81305 (rank : 300)
Query Neighborhood Hits	587	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	P10923, P19008	Gene names	Spp1, Eta-1, Op, Spp-1
Domain Architecture
Description	Osteopontin precursor (Bone sialoprotein-1) (Secreted phosphoprotein 1) (SPP-1) (Minopontin) (Early T-lymphocyte activation 1 protein) (2AR) (Calcium oxalate crystal growth inhibitor protein).

NEB2_MOUSE
NC score	0.016261 (rank : 441)	θ value	0.47712 (rank : 180)
Query Neighborhood Hits	587	Target Neighborhood Hits	889	Shared Neighborhood Hits	47
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

HXD3_HUMAN
NC score	0.016204 (rank : 442)	θ value	0.365318 (rank : 161)
Query Neighborhood Hits	587	Target Neighborhood Hits	433	Shared Neighborhood Hits	57
SwissProt Accessions	P31249, Q99955, Q9BSC5	Gene names	HOXD3, HOX4A
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4A).

SOS1_MOUSE
NC score	0.016186 (rank : 443)	θ value	5.27518 (rank : 475)
Query Neighborhood Hits	587	Target Neighborhood Hits	281	Shared Neighborhood Hits	43
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

CF047_MOUSE
NC score	0.016093 (rank : 444)	θ value	2.36792 (rank : 320)
Query Neighborhood Hits	587	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z1R4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf47 homolog.

HXC9_HUMAN
NC score	0.015981 (rank : 445)	θ value	0.0431538 (rank : 90)
Query Neighborhood Hits	587	Target Neighborhood Hits	339	Shared Neighborhood Hits	24
SwissProt Accessions	P31274, Q9H1I0	Gene names	HOXC9, HOX3B
Domain Architecture
Description	Homeobox protein Hox-C9 (Hox-3B).

HXC9_MOUSE
NC score	0.015951 (rank : 446)	θ value	0.0431538 (rank : 91)
Query Neighborhood Hits	587	Target Neighborhood Hits	338	Shared Neighborhood Hits	24
SwissProt Accessions	P09633	Gene names	Hoxc9, Hox-3.2, Hoxc-9
Domain Architecture
Description	Homeobox protein Hox-C9 (Hox-3.2).

PACS1_MOUSE
NC score	0.015949 (rank : 447)	θ value	4.03905 (rank : 417)
Query Neighborhood Hits	587	Target Neighborhood Hits	87	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K212, Q6P5H8	Gene names	Pacs1
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

CENG1_HUMAN
NC score	0.015755 (rank : 448)	θ value	0.47712 (rank : 174)
Query Neighborhood Hits	587	Target Neighborhood Hits	544	Shared Neighborhood Hits	52
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

TRPM2_HUMAN
NC score	0.015725 (rank : 449)	θ value	1.81305 (rank : 312)
Query Neighborhood Hits	587	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	O94759, Q5KTC2, Q6J3P5, Q96KN6, Q96Q93	Gene names	TRPM2, EREG1, KNP3, LTRPC2, TRPC7
Domain Architecture
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7) (Estrogen- responsive element-associated gene 1 protein).

JPH2_MOUSE
NC score	0.015491 (rank : 450)	θ value	6.88961 (rank : 507)
Query Neighborhood Hits	587	Target Neighborhood Hits	279	Shared Neighborhood Hits	62
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

CN004_HUMAN
NC score	0.015469 (rank : 451)	θ value	8.99809 (rank : 538)
Query Neighborhood Hits	587	Target Neighborhood Hits	108	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H1B7, Q8NDQ2, Q96JG2, Q9H3I7	Gene names	C14orf4, KIAA1865
Domain Architecture	No domain graphic available
Description	Protein C14orf4.

MYCB2_HUMAN
NC score	0.015344 (rank : 452)	θ value	5.27518 (rank : 468)
Query Neighborhood Hits	587	Target Neighborhood Hits	390	Shared Neighborhood Hits	42
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

KCNH2_MOUSE
NC score	0.015255 (rank : 453)	θ value	8.99809 (rank : 559)
Query Neighborhood Hits	587	Target Neighborhood Hits	165	Shared Neighborhood Hits	34
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

EPN1_MOUSE
NC score	0.015048 (rank : 454)	θ value	8.99809 (rank : 550)
Query Neighborhood Hits	587	Target Neighborhood Hits	240	Shared Neighborhood Hits	66
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

GNAS1_HUMAN
NC score	0.014863 (rank : 455)	θ value	3.0926 (rank : 367)
Query Neighborhood Hits	587	Target Neighborhood Hits	278	Shared Neighborhood Hits	68
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

F120C_HUMAN
NC score	0.014831 (rank : 456)	θ value	5.27518 (rank : 447)
Query Neighborhood Hits	587	Target Neighborhood Hits	91	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NX05	Gene names	FAM120C, CXorf17
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120C (Tumor antigen BJ-HCC-21).

CCNT1_MOUSE
NC score	0.014789 (rank : 457)	θ value	0.47712 (rank : 173)
Query Neighborhood Hits	587	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QWV9, Q9Z0U7	Gene names	Ccnt1
Domain Architecture
Description	Cyclin-T1 (CycT1) (Cyclin-T).

TRIPC_HUMAN
NC score	0.014656 (rank : 458)	θ value	2.36792 (rank : 347)
Query Neighborhood Hits	587	Target Neighborhood Hits	319	Shared Neighborhood Hits	40
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

ACK1_MOUSE
NC score	0.014650 (rank : 459)	θ value	0.0330416 (rank : 78)
Query Neighborhood Hits	587	Target Neighborhood Hits	1080	Shared Neighborhood Hits	107
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

FYB_MOUSE
NC score	0.014639 (rank : 460)	θ value	8.99809 (rank : 552)
Query Neighborhood Hits	587	Target Neighborhood Hits	194	Shared Neighborhood Hits	34
SwissProt Accessions	O35601, Q9Z2H3	Gene names	Fyb
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

RIN2_HUMAN
NC score	0.014621 (rank : 461)	θ value	2.36792 (rank : 342)
Query Neighborhood Hits	587	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WYP3, Q00425, Q5TFT8, Q9BQL3, Q9H071	Gene names	RIN2, RASSF4
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2) (Ras inhibitor JC265) (Ras association domain family 4).

PKNX2_MOUSE
NC score	0.014541 (rank : 462)	θ value	3.0926 (rank : 379)
Query Neighborhood Hits	587	Target Neighborhood Hits	197	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BG99, Q8R4B0	Gene names	Pknox2, Prep2
Domain Architecture	No domain graphic available
Description	Homeobox protein PKNOX2 (PBX/knotted homeobox 2) (Homeobox protein PREP-2).

MYRIP_MOUSE
NC score	0.014532 (rank : 463)	θ value	1.81305 (rank : 296)
Query Neighborhood Hits	587	Target Neighborhood Hits	207	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

WDR33_HUMAN
NC score	0.014448 (rank : 464)	θ value	1.06291 (rank : 253)
Query Neighborhood Hits	587	Target Neighborhood Hits	638	Shared Neighborhood Hits	81
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

ASTN_HUMAN
NC score	0.014094 (rank : 465)	θ value	5.27518 (rank : 436)
Query Neighborhood Hits	587	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

FOG1_HUMAN
NC score	0.014091 (rank : 466)	θ value	1.06291 (rank : 240)
Query Neighborhood Hits	587	Target Neighborhood Hits	981	Shared Neighborhood Hits	94
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

ACK1_HUMAN
NC score	0.014084 (rank : 467)	θ value	0.0252991 (rank : 74)
Query Neighborhood Hits	587	Target Neighborhood Hits	1140	Shared Neighborhood Hits	125
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

WNK2_HUMAN
NC score	0.013919 (rank : 468)	θ value	2.36792 (rank : 348)
Query Neighborhood Hits	587	Target Neighborhood Hits	1407	Shared Neighborhood Hits	164
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

SC24D_HUMAN
NC score	0.013901 (rank : 469)	θ value	8.99809 (rank : 577)
Query Neighborhood Hits	587	Target Neighborhood Hits	173	Shared Neighborhood Hits	40
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

TTP_HUMAN
NC score	0.013835 (rank : 470)	θ value	4.03905 (rank : 431)
Query Neighborhood Hits	587	Target Neighborhood Hits	86	Shared Neighborhood Hits	13
SwissProt Accessions	P26651	Gene names	ZFP36, G0S24, TIS11A, TTP
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (G0/G1 switch regulatory protein 24).

FGD1_MOUSE
NC score	0.013793 (rank : 471)	θ value	4.03905 (rank : 399)
Query Neighborhood Hits	587	Target Neighborhood Hits	387	Shared Neighborhood Hits	79
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

CY24A_HUMAN
NC score	0.013765 (rank : 472)	θ value	4.03905 (rank : 394)
Query Neighborhood Hits	587	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	P13498, Q14090, Q9BR72	Gene names	CYBA
Domain Architecture
Description	Cytochrome b-245 light chain (p22 phagocyte B-cytochrome) (Neutrophil cytochrome b 22 kDa polypeptide) (p22-phox) (p22phox) (Cytochrome b(558) alpha chain) (Cytochrome b558 subunit alpha) (Superoxide- generating NADPH oxidase light chain subunit).

NEB2_HUMAN
NC score	0.013713 (rank : 473)	θ value	1.81305 (rank : 298)
Query Neighborhood Hits	587	Target Neighborhood Hits	883	Shared Neighborhood Hits	45
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NFH_HUMAN
NC score	0.013433 (rank : 474)	θ value	1.81305 (rank : 299)
Query Neighborhood Hits	587	Target Neighborhood Hits	1242	Shared Neighborhood Hits	105
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

DDEF1_MOUSE
NC score	0.013419 (rank : 475)	θ value	1.38821 (rank : 259)
Query Neighborhood Hits	587	Target Neighborhood Hits	592	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

SRR35_HUMAN
NC score	0.013371 (rank : 476)	θ value	0.813845 (rank : 230)
Query Neighborhood Hits	587	Target Neighborhood Hits	215	Shared Neighborhood Hits	16
SwissProt Accessions	Q8WXF0, Q8WW25	Gene names	SRRP35
Domain Architecture
Description	35 kDa SR repressor protein (SRrp35).

SHC1_HUMAN
NC score	0.013336 (rank : 477)	θ value	3.0926 (rank : 382)
Query Neighborhood Hits	587	Target Neighborhood Hits	170	Shared Neighborhood Hits	17
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

DCX_MOUSE
NC score	0.013316 (rank : 478)	θ value	8.99809 (rank : 546)
Query Neighborhood Hits	587	Target Neighborhood Hits	124	Shared Neighborhood Hits	40
SwissProt Accessions	O88809	Gene names	Dcx, Dcn
Domain Architecture
Description	Neuronal migration protein doublecortin (Lissencephalin-X) (Lis-X) (Doublin).

CBX6_HUMAN
NC score	0.013272 (rank : 479)	θ value	2.36792 (rank : 318)
Query Neighborhood Hits	587	Target Neighborhood Hits	104	Shared Neighborhood Hits	23
SwissProt Accessions	O95503, Q96EM5	Gene names	CBX6
Domain Architecture
Description	Chromobox protein homolog 6.

SAM14_MOUSE
NC score	0.013233 (rank : 480)	θ value	8.99809 (rank : 575)
Query Neighborhood Hits	587	Target Neighborhood Hits	91	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K070, Q5SWB7, Q8BHE2, Q8C8N5	Gene names	Samd14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

K0174_MOUSE
NC score	0.013190 (rank : 481)	θ value	4.03905 (rank : 405)
Query Neighborhood Hits	587	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	Q9CX00, Q80U68	Gene names	Kiaa0174
Domain Architecture	No domain graphic available
Description	Protein KIAA0174.

JADE2_HUMAN
NC score	0.013187 (rank : 482)	θ value	1.38821 (rank : 263)
Query Neighborhood Hits	587	Target Neighborhood Hits	199	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

ZN219_HUMAN
NC score	0.013038 (rank : 483)	θ value	0.000270298 (rank : 41)
Query Neighborhood Hits	587	Target Neighborhood Hits	876	Shared Neighborhood Hits	68
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

WNK4_HUMAN
NC score	0.013035 (rank : 484)	θ value	0.0736092 (rank : 109)
Query Neighborhood Hits	587	Target Neighborhood Hits	1043	Shared Neighborhood Hits	91
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

DEN4C_HUMAN
NC score	0.012991 (rank : 485)	θ value	1.81305 (rank : 288)
Query Neighborhood Hits	587	Target Neighborhood Hits	63	Shared Neighborhood Hits	8
SwissProt Accessions	Q5VZ89, Q6AI48, Q6ZUB3, Q8NCY7, Q9H6N4, Q9NUT1, Q9NWA5	Gene names	DENND4C, C9orf55
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 4C.

DUS8_HUMAN
NC score	0.012961 (rank : 486)	θ value	0.365318 (rank : 159)
Query Neighborhood Hits	587	Target Neighborhood Hits	161	Shared Neighborhood Hits	26
SwissProt Accessions	Q13202	Gene names	DUSP8, VH5
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH-5).

GCM1_MOUSE
NC score	0.012892 (rank : 487)	θ value	3.0926 (rank : 366)
Query Neighborhood Hits	587	Target Neighborhood Hits	28	Shared Neighborhood Hits	9
SwissProt Accessions	P70348, O09103	Gene names	Gcm1, Gcma
Domain Architecture
Description	Chorion-specific transcription factor GCMa (Glial cells missing homolog 1) (GCM motif protein 1) (mGCMa) (mGCM1).

FBLI1_HUMAN
NC score	0.012890 (rank : 488)	θ value	0.62314 (rank : 191)
Query Neighborhood Hits	587	Target Neighborhood Hits	200	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WUP2, Q5VVE0, Q5VVE1, Q8IX23, Q96T00, Q9UFD6	Gene names	FBLIM1, FBLP1
Domain Architecture
Description	Filamin-binding LIM protein 1 (Filamin-binding LIM protein 1) (FBLP-1) (Mitogen-inducible 2-interacting protein) (MIG2-interacting protein) (Migfilin).

TR150_MOUSE
NC score	0.012860 (rank : 489)	θ value	6.88961 (rank : 527)
Query Neighborhood Hits	587	Target Neighborhood Hits	468	Shared Neighborhood Hits	41
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

FGD1_HUMAN
NC score	0.012703 (rank : 490)	θ value	2.36792 (rank : 327)
Query Neighborhood Hits	587	Target Neighborhood Hits	367	Shared Neighborhood Hits	60
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

SPHK2_MOUSE
NC score	0.012581 (rank : 491)	θ value	6.88961 (rank : 522)
Query Neighborhood Hits	587	Target Neighborhood Hits	78	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JIA7, Q91VA9, Q9DBH6	Gene names	Sphk2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

LPP_MOUSE
NC score	0.012367 (rank : 492)	θ value	6.88961 (rank : 510)
Query Neighborhood Hits	587	Target Neighborhood Hits	247	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BFW7, Q5U407, Q8BHI1, Q8BKI0, Q8BKN2, Q8BLF4, Q8BLG3, Q8C101	Gene names	Lpp
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner homolog.

APBA3_MOUSE
NC score	0.012296 (rank : 493)	θ value	1.81305 (rank : 282)
Query Neighborhood Hits	587	Target Neighborhood Hits	174	Shared Neighborhood Hits	21
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

ABI2_MOUSE
NC score	0.012208 (rank : 494)	θ value	5.27518 (rank : 434)
Query Neighborhood Hits	587	Target Neighborhood Hits	266	Shared Neighborhood Hits	22
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

FA54A_HUMAN
NC score	0.012107 (rank : 495)	θ value	3.0926 (rank : 364)
Query Neighborhood Hits	587	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P444, Q5JWR7, Q6ZUE8, Q7L3U6, Q9BZ39	Gene names	FAM54A, DUFD1
Domain Architecture	No domain graphic available
Description	Protein FAM54A (DUF729 domain-containing protein 1).

SPRE3_HUMAN
NC score	0.012076 (rank : 496)	θ value	8.99809 (rank : 581)
Query Neighborhood Hits	587	Target Neighborhood Hits	65	Shared Neighborhood Hits	23
SwissProt Accessions	Q2MJR0	Gene names	SPRED3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).

TTLL5_HUMAN
NC score	0.012048 (rank : 497)	θ value	1.81305 (rank : 313)
Query Neighborhood Hits	587	Target Neighborhood Hits	141	Shared Neighborhood Hits	23
SwissProt Accessions	Q6EMB2, Q9P1V5, Q9UPZ4	Gene names	TTLL5, KIAA0998, STAMP
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5 (SRC1 and TIF2-associated modulatory protein).

SHC1_MOUSE
NC score	0.011990 (rank : 498)	θ value	1.06291 (rank : 250)
Query Neighborhood Hits	587	Target Neighborhood Hits	180	Shared Neighborhood Hits	18
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

JHD2C_MOUSE
NC score	0.011939 (rank : 499)	θ value	1.38821 (rank : 264)
Query Neighborhood Hits	587	Target Neighborhood Hits	297	Shared Neighborhood Hits	33
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

JHD3B_MOUSE
NC score	0.011799 (rank : 500)	θ value	2.36792 (rank : 334)
Query Neighborhood Hits	587	Target Neighborhood Hits	152	Shared Neighborhood Hits	29
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

SPN90_HUMAN
NC score	0.011791 (rank : 501)	θ value	2.36792 (rank : 343)
Query Neighborhood Hits	587	Target Neighborhood Hits	157	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

GGA3_MOUSE
NC score	0.011755 (rank : 502)	θ value	4.03905 (rank : 403)
Query Neighborhood Hits	587	Target Neighborhood Hits	148	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

ACE2_MOUSE
NC score	0.011697 (rank : 503)	θ value	3.0926 (rank : 352)
Query Neighborhood Hits	587	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R0I0, Q99N70, Q99N71	Gene names	Ace2
Domain Architecture	No domain graphic available
Description	Angiotensin-converting enzyme 2 precursor (EC 3.4.17.-) (ACE-related carboxypeptidase).

UBP31_HUMAN
NC score	0.011611 (rank : 504)	θ value	8.99809 (rank : 583)
Query Neighborhood Hits	587	Target Neighborhood Hits	293	Shared Neighborhood Hits	47
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

CREB1_MOUSE
NC score	0.011581 (rank : 505)	θ value	3.0926 (rank : 362)
Query Neighborhood Hits	587	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	Q01147	Gene names	Creb1, Creb-1
Domain Architecture
Description	cAMP response element-binding protein (CREB).

NFAT5_MOUSE
NC score	0.011503 (rank : 506)	θ value	1.38821 (rank : 269)
Query Neighborhood Hits	587	Target Neighborhood Hits	162	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

BACH_MOUSE
NC score	0.011499 (rank : 507)	θ value	5.27518 (rank : 438)
Query Neighborhood Hits	587	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q91V12, Q59HQ2	Gene names	Acot7, Bach
Domain Architecture
Description	Cytosolic acyl coenzyme A thioester hydrolase (EC 3.1.2.2) (Long chain acyl-CoA thioester hydrolase) (CTE-II) (CTE-IIa) (Brain acyl-CoA hydrolase) (Acyl-CoA thioesterase 7).

SPEG_HUMAN
NC score	0.011489 (rank : 508)	θ value	5.27518 (rank : 477)
Query Neighborhood Hits	587	Target Neighborhood Hits	1762	Shared Neighborhood Hits	184
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

BACH_HUMAN
NC score	0.011466 (rank : 509)	θ value	5.27518 (rank : 437)
Query Neighborhood Hits	587	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	O00154, O43703, Q5JYL4, Q9UJM9, Q9Y539, Q9Y540	Gene names	ACOT7, BACH
Domain Architecture
Description	Cytosolic acyl coenzyme A thioester hydrolase (EC 3.1.2.2) (Long chain acyl-CoA thioester hydrolase) (CTE-II) (CTE-IIa) (Brain acyl-CoA hydrolase) (Acyl-CoA thioesterase 7).

CREB1_HUMAN
NC score	0.011355 (rank : 510)	θ value	3.0926 (rank : 361)
Query Neighborhood Hits	587	Target Neighborhood Hits	57	Shared Neighborhood Hits	6
SwissProt Accessions	P16220, P21934, Q9UMA7	Gene names	CREB1
Domain Architecture
Description	cAMP response element-binding protein (CREB).

M3K11_HUMAN
NC score	0.011336 (rank : 511)	θ value	0.00102713 (rank : 51)
Query Neighborhood Hits	587	Target Neighborhood Hits	1136	Shared Neighborhood Hits	75
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

PRDM2_HUMAN
NC score	0.011185 (rank : 512)	θ value	1.81305 (rank : 303)
Query Neighborhood Hits	587	Target Neighborhood Hits	1135	Shared Neighborhood Hits	95
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

COCA1_MOUSE
NC score	0.011074 (rank : 513)	θ value	8.99809 (rank : 541)
Query Neighborhood Hits	587	Target Neighborhood Hits	467	Shared Neighborhood Hits	58
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COEA1_HUMAN
NC score	0.011053 (rank : 514)	θ value	8.99809 (rank : 542)
Query Neighborhood Hits	587	Target Neighborhood Hits	427	Shared Neighborhood Hits	58
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

HES7_MOUSE
NC score	0.010776 (rank : 515)	θ value	6.88961 (rank : 504)
Query Neighborhood Hits	587	Target Neighborhood Hits	72	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BKT2, Q99JA6	Gene names	Hes7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

NCOA1_MOUSE
NC score	0.010655 (rank : 516)	θ value	3.0926 (rank : 376)
Query Neighborhood Hits	587	Target Neighborhood Hits	196	Shared Neighborhood Hits	44
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

HD_HUMAN
NC score	0.010653 (rank : 517)	θ value	5.27518 (rank : 453)
Query Neighborhood Hits	587	Target Neighborhood Hits	165	Shared Neighborhood Hits	22
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

COEA1_MOUSE
NC score	0.010577 (rank : 518)	θ value	8.99809 (rank : 543)
Query Neighborhood Hits	587	Target Neighborhood Hits	402	Shared Neighborhood Hits	57
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

HNRPL_MOUSE
NC score	0.010538 (rank : 519)	θ value	2.36792 (rank : 329)
Query Neighborhood Hits	587	Target Neighborhood Hits	34	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R081, O54789, Q8K0S7	Gene names	Hnrpl
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein L (hnRNP L).

NOP56_HUMAN
NC score	0.010483 (rank : 520)	θ value	2.36792 (rank : 339)
Query Neighborhood Hits	587	Target Neighborhood Hits	95	Shared Neighborhood Hits	5
SwissProt Accessions	O00567, Q9NQ05	Gene names	NOL5A, NOP56
Domain Architecture
Description	Nucleolar protein Nop56 (Nucleolar protein 5A).

DAB2P_HUMAN
NC score	0.010392 (rank : 521)	θ value	2.36792 (rank : 325)
Query Neighborhood Hits	587	Target Neighborhood Hits	303	Shared Neighborhood Hits	29
SwissProt Accessions	Q5VWQ8, Q8TDL2, Q96SE1, Q9C0C0	Gene names	DAB2IP, AF9Q34, AIP1, KIAA1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein) (DAB2 interaction protein) (ASK-interacting protein 1).

FIGN_HUMAN
NC score	0.010320 (rank : 522)	θ value	1.81305 (rank : 290)
Query Neighborhood Hits	587	Target Neighborhood Hits	176	Shared Neighborhood Hits	23
SwissProt Accessions	Q5HY92, Q9H6M5, Q9NVZ9	Gene names	FIGN
Domain Architecture	No domain graphic available
Description	Fidgetin.

PHAR3_HUMAN
NC score	0.010315 (rank : 523)	θ value	6.88961 (rank : 513)
Query Neighborhood Hits	587	Target Neighborhood Hits	169	Shared Neighborhood Hits	20
SwissProt Accessions	Q96KR7, Q707P6, Q9H4T4	Gene names	PHACTR3, C20orf101, SCAPIN1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

EP15R_MOUSE
NC score	0.010068 (rank : 524)	θ value	1.81305 (rank : 289)
Query Neighborhood Hits	587	Target Neighborhood Hits	1135	Shared Neighborhood Hits	56
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

F100A_HUMAN
NC score	0.010018 (rank : 525)	θ value	6.88961 (rank : 500)
Query Neighborhood Hits	587	Target Neighborhood Hits	39	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TB05, Q71MF6	Gene names	FAM100A
Domain Architecture	No domain graphic available
Description	Protein FAM100A.

TFE2_MOUSE
NC score	0.009988 (rank : 526)	θ value	2.36792 (rank : 346)
Query Neighborhood Hits	587	Target Neighborhood Hits	118	Shared Neighborhood Hits	16
SwissProt Accessions	P15806, Q3U153, Q8CAH9, Q8VCY4, Q922S2, Q99MB8, Q9CYJ4	Gene names	Tcf3, Alf2, Me2, Tcfe2a
Domain Architecture	No domain graphic available
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Transcription factor A1).

WBP2_HUMAN
NC score	0.009909 (rank : 527)	θ value	6.88961 (rank : 530)
Query Neighborhood Hits	587	Target Neighborhood Hits	55	Shared Neighborhood Hits	8
SwissProt Accessions	Q969T9, O95638	Gene names	WBP2
Domain Architecture
Description	WW domain-binding protein 2 (WBP-2).

PKNX2_HUMAN
NC score	0.009870 (rank : 528)	θ value	4.03905 (rank : 421)
Query Neighborhood Hits	587	Target Neighborhood Hits	133	Shared Neighborhood Hits	17
SwissProt Accessions	Q96KN3, Q63HL6, Q86XD1	Gene names	PKNOX2, PREP2
Domain Architecture
Description	Homeobox protein PKNOX2 (PBX/knotted homeobox 2) (Homeobox protein PREP-2).

ZEP1_MOUSE
NC score	0.009807 (rank : 529)	θ value	2.36792 (rank : 351)
Query Neighborhood Hits	587	Target Neighborhood Hits	1063	Shared Neighborhood Hits	107
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

TMEM8_MOUSE
NC score	0.009789 (rank : 530)	θ value	4.03905 (rank : 430)
Query Neighborhood Hits	587	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ESN3, Q99JS5	Gene names	Tmem8
Domain Architecture	No domain graphic available
Description	Transmembrane protein 8 precursor (M83 protein).

TEX14_MOUSE
NC score	0.009730 (rank : 531)	θ value	1.81305 (rank : 309)
Query Neighborhood Hits	587	Target Neighborhood Hits	1333	Shared Neighborhood Hits	72
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

ARI5B_MOUSE
NC score	0.009716 (rank : 532)	θ value	8.99809 (rank : 533)
Query Neighborhood Hits	587	Target Neighborhood Hits	158	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BM75, Q8C0E0, Q8K4G8, Q8K4L9, Q9CU78, Q9JIX4	Gene names	Arid5b, Desrt, Mrf2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (MRF1-like) (Modulator recognition factor protein 2) (MRF-2) (Developmentally and sexually retarded with transient immune abnormalities protein).

SOS2_HUMAN
NC score	0.009712 (rank : 533)	θ value	4.03905 (rank : 428)
Query Neighborhood Hits	587	Target Neighborhood Hits	193	Shared Neighborhood Hits	27
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

GAK_HUMAN
NC score	0.009547 (rank : 534)	θ value	0.813845 (rank : 219)
Query Neighborhood Hits	587	Target Neighborhood Hits	1028	Shared Neighborhood Hits	95
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

EP15R_HUMAN
NC score	0.009536 (rank : 535)	θ value	0.47712 (rank : 176)
Query Neighborhood Hits	587	Target Neighborhood Hits	1083	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

ZMYM3_HUMAN
NC score	0.009524 (rank : 536)	θ value	8.99809 (rank : 587)
Query Neighborhood Hits	587	Target Neighborhood Hits	223	Shared Neighborhood Hits	45
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

DDFL1_MOUSE
NC score	0.009159 (rank : 537)	θ value	4.03905 (rank : 395)
Query Neighborhood Hits	587	Target Neighborhood Hits	324	Shared Neighborhood Hits	21
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

DREB_MOUSE
NC score	0.009141 (rank : 538)	θ value	6.88961 (rank : 498)
Query Neighborhood Hits	587	Target Neighborhood Hits	446	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

CTGE2_HUMAN
NC score	0.009060 (rank : 539)	θ value	0.813845 (rank : 214)
Query Neighborhood Hits	587	Target Neighborhood Hits	594	Shared Neighborhood Hits	21
SwissProt Accessions	Q96RT6	Gene names	CTAGE1, CTAGE2
Domain Architecture	No domain graphic available
Description	Protein cTAGE-2.

FIGN_MOUSE
NC score	0.009019 (rank : 540)	θ value	2.36792 (rank : 328)
Query Neighborhood Hits	587	Target Neighborhood Hits	165	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ERZ6, Q3TPB0, Q3UP57, Q6PCM0	Gene names	Fign
Domain Architecture	No domain graphic available
Description	Fidgetin.

HXA13_HUMAN
NC score	0.008989 (rank : 541)	θ value	2.36792 (rank : 330)
Query Neighborhood Hits	587	Target Neighborhood Hits	353	Shared Neighborhood Hits	25
SwissProt Accessions	P31271, O43371	Gene names	HOXA13, HOX1J
Domain Architecture
Description	Homeobox protein Hox-A13 (Hox-1J).

ITPR1_HUMAN
NC score	0.008949 (rank : 542)	θ value	5.27518 (rank : 457)
Query Neighborhood Hits	587	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q14643, Q14660, Q99897	Gene names	ITPR1, INSP3R1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (IP3R).

ITPR1_MOUSE
NC score	0.008903 (rank : 543)	θ value	5.27518 (rank : 458)
Query Neighborhood Hits	587	Target Neighborhood Hits	99	Shared Neighborhood Hits	10
SwissProt Accessions	P11881, P20943, Q99LG5	Gene names	Itpr1, Insp3r, Pcd6, Pcp1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (Inositol 1,4,5-trisphosphate-binding protein P400) (Purkinje cell protein 1) (Protein PCD-6).

SMAL1_MOUSE
NC score	0.008894 (rank : 544)	θ value	8.99809 (rank : 580)
Query Neighborhood Hits	587	Target Neighborhood Hits	157	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

HES7_HUMAN
NC score	0.008890 (rank : 545)	θ value	8.99809 (rank : 553)
Query Neighborhood Hits	587	Target Neighborhood Hits	72	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BYE0	Gene names	HES7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

RAVR2_MOUSE
NC score	0.008713 (rank : 546)	θ value	5.27518 (rank : 473)
Query Neighborhood Hits	587	Target Neighborhood Hits	137	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TPD6	Gene names	Raver2, Kiaa1579
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 2 (Protein raver-2).

IL29_HUMAN
NC score	0.008665 (rank : 547)	θ value	5.27518 (rank : 456)
Query Neighborhood Hits	587	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IU54	Gene names	IL29, IFNL1, ZCYTO21
Domain Architecture	No domain graphic available
Description	Interleukin-29 precursor (IL-29) (Interferon lambda-1) (IFN-lambda-1) (Cytokine ZCYTO21).

FOXGA_HUMAN
NC score	0.008642 (rank : 548)	θ value	1.06291 (rank : 241)
Query Neighborhood Hits	587	Target Neighborhood Hits	132	Shared Neighborhood Hits	17
SwissProt Accessions	P55316	Gene names	FOXG1A, FKHL2
Domain Architecture
Description	Forkhead box protein G1A (Forkhead-related protein FKHL2) (Transcription factor BF-2) (Brain factor 2) (BF2) (HFK2).

SIX5_HUMAN
NC score	0.008599 (rank : 549)	θ value	8.99809 (rank : 579)
Query Neighborhood Hits	587	Target Neighborhood Hits	386	Shared Neighborhood Hits	47
SwissProt Accessions	Q8N196	Gene names	SIX5, DMAHP
Domain Architecture	No domain graphic available
Description	Homeobox protein SIX5 (DM locus-associated homeodomain protein).

TMM46_MOUSE
NC score	0.008590 (rank : 550)	θ value	6.88961 (rank : 526)
Query Neighborhood Hits	587	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q8QZV2, Q8BN61	Gene names	Tmem46
Domain Architecture	No domain graphic available
Description	Transmembrane protein 46 homolog precursor.

RN169_HUMAN
NC score	0.008502 (rank : 551)	θ value	6.88961 (rank : 518)
Query Neighborhood Hits	587	Target Neighborhood Hits	203	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

PMS2_HUMAN
NC score	0.008469 (rank : 552)	θ value	8.99809 (rank : 571)
Query Neighborhood Hits	587	Target Neighborhood Hits	131	Shared Neighborhood Hits	26
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

HXB2_MOUSE
NC score	0.008415 (rank : 553)	θ value	3.0926 (rank : 369)
Query Neighborhood Hits	587	Target Neighborhood Hits	350	Shared Neighborhood Hits	28
SwissProt Accessions	P0C1T1	Gene names	Hoxb2, Hox-2.8
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-B2 (Hox-2.8).

UBP21_HUMAN
NC score	0.008398 (rank : 554)	θ value	0.47712 (rank : 185)
Query Neighborhood Hits	587	Target Neighborhood Hits	95	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

MYPN_MOUSE
NC score	0.008278 (rank : 555)	θ value	0.62314 (rank : 198)
Query Neighborhood Hits	587	Target Neighborhood Hits	421	Shared Neighborhood Hits	29
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

EMIL2_HUMAN
NC score	0.008217 (rank : 556)	θ value	8.99809 (rank : 549)
Query Neighborhood Hits	587	Target Neighborhood Hits	573	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BXX0, Q8NBH3, Q96JQ4	Gene names	EMILIN2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Protein FOAP-10).

OTX1_HUMAN
NC score	0.008213 (rank : 557)	θ value	1.06291 (rank : 247)
Query Neighborhood Hits	587	Target Neighborhood Hits	379	Shared Neighborhood Hits	26
SwissProt Accessions	P32242, Q53TG6	Gene names	OTX1
Domain Architecture
Description	Homeobox protein OTX1.

RHG06_HUMAN
NC score	0.008163 (rank : 558)	θ value	8.99809 (rank : 573)
Query Neighborhood Hits	587	Target Neighborhood Hits	114	Shared Neighborhood Hits	18
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

CTGE5_HUMAN
NC score	0.008124 (rank : 559)	θ value	1.81305 (rank : 287)
Query Neighborhood Hits	587	Target Neighborhood Hits	800	Shared Neighborhood Hits	36
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

PDXL2_HUMAN
NC score	0.008120 (rank : 560)	θ value	8.99809 (rank : 568)
Query Neighborhood Hits	587	Target Neighborhood Hits	75	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NZ53, Q6UVY4, Q8WUV6	Gene names	PODXL2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

LAP4_HUMAN
NC score	0.008100 (rank : 561)	θ value	2.36792 (rank : 337)
Query Neighborhood Hits	587	Target Neighborhood Hits	608	Shared Neighborhood Hits	48
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

TENX_HUMAN
NC score	0.008085 (rank : 562)	θ value	0.0961366 (rank : 122)
Query Neighborhood Hits	587	Target Neighborhood Hits	789	Shared Neighborhood Hits	50
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

MS3L1_HUMAN
NC score	0.008037 (rank : 563)	θ value	8.99809 (rank : 564)
Query Neighborhood Hits	587	Target Neighborhood Hits	60	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N5Y2, Q9UG70, Q9Y5Z8	Gene names	MSL3L1
Domain Architecture
Description	Male-specific lethal 3-like 1 (MSL3-like 1) (Male-specific lethal-3 homolog 1).

MEGF8_MOUSE
NC score	0.007978 (rank : 564)	θ value	1.81305 (rank : 294)
Query Neighborhood Hits	587	Target Neighborhood Hits	520	Shared Neighborhood Hits	15
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

CTGE6_HUMAN
NC score	0.007942 (rank : 565)	θ value	8.99809 (rank : 544)
Query Neighborhood Hits	587	Target Neighborhood Hits	650	Shared Neighborhood Hits	43
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

HXA13_MOUSE
NC score	0.007794 (rank : 566)	θ value	5.27518 (rank : 454)
Query Neighborhood Hits	587	Target Neighborhood Hits	351	Shared Neighborhood Hits	24
SwissProt Accessions	Q62424	Gene names	Hoxa13, Hox-1.10
Domain Architecture
Description	Homeobox protein Hox-A13 (Hox-1.10).

POMT1_MOUSE
NC score	0.007778 (rank : 567)	θ value	4.03905 (rank : 422)
Query Neighborhood Hits	587	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R2R1, Q3UYD8, Q64J18, Q8BPJ6, Q8BPU1, Q8R474	Gene names	Pomt1
Domain Architecture
Description	Protein O-mannosyl-transferase 1 (EC 2.4.1.109) (Dolichyl-phosphate- mannose--protein mannosyltransferase 1).

I17RD_HUMAN
NC score	0.007766 (rank : 568)	θ value	5.27518 (rank : 455)
Query Neighborhood Hits	587	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NFM7, Q58EZ7, Q6RVF4, Q6UWI5, Q8N113, Q8NFS0, Q9UFA0	Gene names	IL17RD, IL17RLM, SEF
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor D precursor (IL-17 receptor D) (IL-17RD) (Interleukin-17D receptor) (IL-17D receptor) (IL17Rhom) (Interleukin- 17 receptor-like protein) (Sef homolog) (hSef).

HNRPL_HUMAN
NC score	0.007759 (rank : 569)	θ value	8.99809 (rank : 554)
Query Neighborhood Hits	587	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	P14866, Q9H3P3	Gene names	HNRPL
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein L (hnRNP L).

ANKS6_HUMAN
NC score	0.007664 (rank : 570)	θ value	3.0926 (rank : 353)
Query Neighborhood Hits	587	Target Neighborhood Hits	411	Shared Neighborhood Hits	39
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

FBLN2_MOUSE
NC score	0.007597 (rank : 571)	θ value	0.47712 (rank : 177)
Query Neighborhood Hits	587	Target Neighborhood Hits	505	Shared Neighborhood Hits	65
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

HXB2_HUMAN
NC score	0.007580 (rank : 572)	θ value	8.99809 (rank : 555)
Query Neighborhood Hits	587	Target Neighborhood Hits	367	Shared Neighborhood Hits	31
SwissProt Accessions	P14652, P10913, P17485	Gene names	HOXB2, HOX2H
Domain Architecture
Description	Homeobox protein Hox-B2 (Hox-2H) (Hox-2.8) (K8).

FOXC2_HUMAN
NC score	0.007535 (rank : 573)	θ value	5.27518 (rank : 449)
Query Neighborhood Hits	587	Target Neighborhood Hits	236	Shared Neighborhood Hits	49
SwissProt Accessions	Q99958	Gene names	FOXC2, FKHL14, MFH1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

APS_HUMAN
NC score	0.007149 (rank : 574)	θ value	6.88961 (rank : 492)
Query Neighborhood Hits	587	Target Neighborhood Hits	162	Shared Neighborhood Hits	15
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

TREX1_HUMAN
NC score	0.007017 (rank : 575)	θ value	6.88961 (rank : 528)
Query Neighborhood Hits	587	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NSU2, Q8TEU2, Q9BPW1, Q9Y4X2	Gene names	TREX1
Domain Architecture
Description	Three prime repair exonuclease 1 (EC 3.1.11.2) (3'-5' exonuclease TREX1) (DNase III).

OTX1_MOUSE
NC score	0.006982 (rank : 576)	θ value	3.0926 (rank : 378)
Query Neighborhood Hits	587	Target Neighborhood Hits	372	Shared Neighborhood Hits	25
SwissProt Accessions	P80205	Gene names	Otx1, Otx-1
Domain Architecture
Description	Homeobox protein OTX1.

RX_HUMAN
NC score	0.006974 (rank : 577)	θ value	1.81305 (rank : 305)
Query Neighborhood Hits	587	Target Neighborhood Hits	423	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y2V3	Gene names	RAX, RX
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

DAB2P_MOUSE
NC score	0.006862 (rank : 578)	θ value	8.99809 (rank : 545)
Query Neighborhood Hits	587	Target Neighborhood Hits	284	Shared Neighborhood Hits	21
SwissProt Accessions	Q3UHC7, Q3TPD5, Q3UH44, Q6JTV1, Q80T97	Gene names	Dab2ip, Kiaa1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein).

BAI1_HUMAN
NC score	0.006753 (rank : 579)	θ value	1.38821 (rank : 254)
Query Neighborhood Hits	587	Target Neighborhood Hits	375	Shared Neighborhood Hits	48
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

SYT3_MOUSE
NC score	0.006694 (rank : 580)	θ value	1.38821 (rank : 275)
Query Neighborhood Hits	587	Target Neighborhood Hits	147	Shared Neighborhood Hits	11
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

DTNB_MOUSE
NC score	0.006612 (rank : 581)	θ value	4.03905 (rank : 396)
Query Neighborhood Hits	587	Target Neighborhood Hits	263	Shared Neighborhood Hits	21
SwissProt Accessions	O70585, O70563, Q9CTZ1	Gene names	Dtnb
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B) (MDTN-B).

SALL3_HUMAN
NC score	0.006384 (rank : 582)	θ value	1.81305 (rank : 306)
Query Neighborhood Hits	587	Target Neighborhood Hits	1066	Shared Neighborhood Hits	93
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

SOX9_HUMAN
NC score	0.006309 (rank : 583)	θ value	4.03905 (rank : 429)
Query Neighborhood Hits	587	Target Neighborhood Hits	210	Shared Neighborhood Hits	33
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.

MYCL1_MOUSE
NC score	0.006250 (rank : 584)	θ value	5.27518 (rank : 469)
Query Neighborhood Hits	587	Target Neighborhood Hits	123	Shared Neighborhood Hits	9
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

STAG3_MOUSE
NC score	0.006228 (rank : 585)	θ value	3.0926 (rank : 386)
Query Neighborhood Hits	587	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	O70576	Gene names	Stag3
Domain Architecture
Description	Cohesin subunit SA-3 (Stromal antigen 3) (Stromalin 3) (SCC3 homolog 3).

MEGF8_HUMAN
NC score	0.006167 (rank : 586)	θ value	5.27518 (rank : 464)
Query Neighborhood Hits	587	Target Neighborhood Hits	528	Shared Neighborhood Hits	20
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

FXR2_HUMAN
NC score	0.006111 (rank : 587)	θ value	4.03905 (rank : 401)
Query Neighborhood Hits	587	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	P51116, Q8WUM2	Gene names	FXR2
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

ANR40_MOUSE
NC score	0.005792 (rank : 588)	θ value	6.88961 (rank : 491)
Query Neighborhood Hits	587	Target Neighborhood Hits	228	Shared Neighborhood Hits	19
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

M3K9_HUMAN
NC score	0.005671 (rank : 589)	θ value	0.62314 (rank : 197)
Query Neighborhood Hits	587	Target Neighborhood Hits	1123	Shared Neighborhood Hits	59
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

RXRB_HUMAN
NC score	0.005626 (rank : 590)	θ value	0.813845 (rank : 229)
Query Neighborhood Hits	587	Target Neighborhood Hits	280	Shared Neighborhood Hits	45
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

ADA15_MOUSE
NC score	0.005573 (rank : 591)	θ value	1.81305 (rank : 279)
Query Neighborhood Hits	587	Target Neighborhood Hits	324	Shared Neighborhood Hits	22
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

SATB1_MOUSE
NC score	0.005517 (rank : 592)	θ value	8.99809 (rank : 576)
Query Neighborhood Hits	587	Target Neighborhood Hits	130	Shared Neighborhood Hits	20
SwissProt Accessions	Q60611	Gene names	Satb1
Domain Architecture
Description	DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1).

KSR1_MOUSE
NC score	0.005281 (rank : 593)	θ value	0.47712 (rank : 179)
Query Neighborhood Hits	587	Target Neighborhood Hits	870	Shared Neighborhood Hits	36
SwissProt Accessions	Q61097, Q61648, Q78DX8	Gene names	Ksr1, Ksr
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein).

ADA15_HUMAN
NC score	0.005178 (rank : 594)	θ value	0.62314 (rank : 186)
Query Neighborhood Hits	587	Target Neighborhood Hits	288	Shared Neighborhood Hits	14
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

TBX19_MOUSE
NC score	0.005146 (rank : 595)	θ value	2.36792 (rank : 345)
Query Neighborhood Hits	587	Target Neighborhood Hits	65	Shared Neighborhood Hits	10
SwissProt Accessions	Q99ME7	Gene names	Tbx19, Tpit
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX19 (T-box protein 19) (T-box factor, pituitary).

BARD1_MOUSE
NC score	0.005081 (rank : 596)	θ value	5.27518 (rank : 439)
Query Neighborhood Hits	587	Target Neighborhood Hits	411	Shared Neighborhood Hits	23
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

LUZP1_MOUSE
NC score	0.004935 (rank : 597)	θ value	8.99809 (rank : 561)
Query Neighborhood Hits	587	Target Neighborhood Hits	940	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

JUNB_MOUSE
NC score	0.004911 (rank : 598)	θ value	8.99809 (rank : 557)
Query Neighborhood Hits	587	Target Neighborhood Hits	116	Shared Neighborhood Hits	12
SwissProt Accessions	P09450, Q8C2G9	Gene names	Junb, Jun-b
Domain Architecture
Description	Transcription factor jun-B.

PHLPP_MOUSE
NC score	0.004757 (rank : 599)	θ value	1.06291 (rank : 248)
Query Neighborhood Hits	587	Target Neighborhood Hits	394	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

CHSTC_HUMAN
NC score	0.004628 (rank : 600)	θ value	5.27518 (rank : 442)
Query Neighborhood Hits	587	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NRB3, Q9NXY7	Gene names	CHST12
Domain Architecture	No domain graphic available
Description	Carbohydrate sulfotransferase 12 (EC 2.8.2.5) (Chondroitin 4-O- sulfotransferase 2) (Chondroitin 4-sulfotransferase 2) (C4ST2) (C4ST- 2) (Sulfotransferase Hlo).

LAP4_MOUSE
NC score	0.004604 (rank : 601)	θ value	6.88961 (rank : 508)
Query Neighborhood Hits	587	Target Neighborhood Hits	590	Shared Neighborhood Hits	47
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

MAST1_MOUSE
NC score	0.004599 (rank : 602)	θ value	1.06291 (rank : 244)
Query Neighborhood Hits	587	Target Neighborhood Hits	1123	Shared Neighborhood Hits	76
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

LIRB4_HUMAN
NC score	0.004427 (rank : 603)	θ value	3.0926 (rank : 372)
Query Neighborhood Hits	587	Target Neighborhood Hits	111	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NHJ6, O15468, O75021, Q8N1C7, Q8NHL5	Gene names	LILRB4, ILT3, LIR5
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 4 precursor (Leukocyte immunoglobulin-like receptor 5) (LIR-5) (Immunoglobulin- like transcript 3) (ILT-3) (Monocyte inhibitory receptor HM18) (CD85k antigen).

ABL1_MOUSE
NC score	0.004402 (rank : 604)	θ value	2.36792 (rank : 315)
Query Neighborhood Hits	587	Target Neighborhood Hits	1178	Shared Neighborhood Hits	83
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

CENG3_HUMAN
NC score	0.004134 (rank : 605)	θ value	8.99809 (rank : 537)
Query Neighborhood Hits	587	Target Neighborhood Hits	455	Shared Neighborhood Hits	20
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

YAP1_MOUSE
NC score	0.004020 (rank : 606)	θ value	8.99809 (rank : 585)
Query Neighborhood Hits	587	Target Neighborhood Hits	96	Shared Neighborhood Hits	14
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

BAI1_MOUSE
NC score	0.003783 (rank : 607)	θ value	4.03905 (rank : 391)
Query Neighborhood Hits	587	Target Neighborhood Hits	340	Shared Neighborhood Hits	30
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

ROBO4_MOUSE
NC score	0.003626 (rank : 608)	θ value	3.0926 (rank : 381)
Query Neighborhood Hits	587	Target Neighborhood Hits	358	Shared Neighborhood Hits	18
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

LRCH4_MOUSE
NC score	0.003413 (rank : 609)	θ value	3.0926 (rank : 374)
Query Neighborhood Hits	587	Target Neighborhood Hits	302	Shared Neighborhood Hits	20
SwissProt Accessions	Q921G6	Gene names	Lrch4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4.

PANK1_MOUSE
NC score	0.003353 (rank : 610)	θ value	8.99809 (rank : 566)
Query Neighborhood Hits	587	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K4K6, Q9D3K1, Q9QXM8	Gene names	Pank1, Pank
Domain Architecture
Description	Pantothenate kinase 1 (EC 2.7.1.33) (Pantothenic acid kinase 1) (mPank1) (mPank).

PCGF2_MOUSE
NC score	0.003350 (rank : 611)	θ value	8.99809 (rank : 567)
Query Neighborhood Hits	587	Target Neighborhood Hits	213	Shared Neighborhood Hits	15
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

SSX4_HUMAN
NC score	0.003178 (rank : 612)	θ value	6.88961 (rank : 523)
Query Neighborhood Hits	587	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	O60224, Q5JQZ0, Q9UJU9	Gene names	SSX4
Domain Architecture
Description	Protein SSX4.

PAK6_HUMAN
NC score	0.003110 (rank : 613)	θ value	0.0330416 (rank : 85)
Query Neighborhood Hits	587	Target Neighborhood Hits	915	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NQU5	Gene names	PAK6, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (p21-activated kinase 6) (PAK-6) (PAK-5).

P85B_HUMAN
NC score	0.003047 (rank : 614)	θ value	5.27518 (rank : 470)
Query Neighborhood Hits	587	Target Neighborhood Hits	543	Shared Neighborhood Hits	34
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

RXRB_MOUSE
NC score	0.003024 (rank : 615)	θ value	8.99809 (rank : 574)
Query Neighborhood Hits	587	Target Neighborhood Hits	230	Shared Neighborhood Hits	37
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

M3K1_MOUSE
NC score	0.002980 (rank : 616)	θ value	1.06291 (rank : 243)
Query Neighborhood Hits	587	Target Neighborhood Hits	952	Shared Neighborhood Hits	48
SwissProt Accessions	P53349, Q60831, Q9R0U3, Q9R256	Gene names	Map3k1, Mekk, Mekk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1).

MK07_MOUSE
NC score	0.002945 (rank : 617)	θ value	1.06291 (rank : 245)
Query Neighborhood Hits	587	Target Neighborhood Hits	1054	Shared Neighborhood Hits	75
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

ELK1_HUMAN
NC score	0.002590 (rank : 618)	θ value	8.99809 (rank : 547)
Query Neighborhood Hits	587	Target Neighborhood Hits	112	Shared Neighborhood Hits	17
SwissProt Accessions	P19419, O75606, O95058, Q969X8, Q9UJM4	Gene names	ELK1
Domain Architecture
Description	ETS domain-containing protein Elk-1.

LHX3_MOUSE
NC score	0.002581 (rank : 619)	θ value	6.88961 (rank : 509)
Query Neighborhood Hits	587	Target Neighborhood Hits	451	Shared Neighborhood Hits	26
SwissProt Accessions	P50481, Q61800, Q61801	Gene names	Lhx3, Lim-3, Lim3, Plim
Domain Architecture
Description	LIM/homeobox protein Lhx3 (Homeobox protein LIM-3) (Homeobox protein P-LIM) (LIM homeobox protein 3).

ITIH1_MOUSE
NC score	0.002457 (rank : 620)	θ value	8.99809 (rank : 556)
Query Neighborhood Hits	587	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q61702	Gene names	Itih1
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H1 precursor (ITI heavy chain H1) (Inter-alpha-inhibitor heavy chain 1).

KIFC2_HUMAN
NC score	0.002242 (rank : 621)	θ value	4.03905 (rank : 408)
Query Neighborhood Hits	587	Target Neighborhood Hits	237	Shared Neighborhood Hits	19
SwissProt Accessions	Q96AC6	Gene names	KIFC2
Domain Architecture
Description	Kinesin-like protein KIFC2.

INSM1_MOUSE
NC score	0.001717 (rank : 622)	θ value	1.81305 (rank : 293)
Query Neighborhood Hits	587	Target Neighborhood Hits	678	Shared Neighborhood Hits	25
SwissProt Accessions	Q63ZV0, Q9Z113	Gene names	Insm1, Ia1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

KIRR2_MOUSE
NC score	0.001455 (rank : 623)	θ value	2.36792 (rank : 336)
Query Neighborhood Hits	587	Target Neighborhood Hits	326	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

FOXC2_MOUSE
NC score	0.001429 (rank : 624)	θ value	8.99809 (rank : 551)
Query Neighborhood Hits	587	Target Neighborhood Hits	124	Shared Neighborhood Hits	10
SwissProt Accessions	Q61850, P97948, Q63869, Q8C694	Gene names	Foxc2, Fkh14, Fkhl14, Mfh1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

FAK2_MOUSE
NC score	0.001397 (rank : 625)	θ value	6.88961 (rank : 502)
Query Neighborhood Hits	587	Target Neighborhood Hits	851	Shared Neighborhood Hits	29
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

FAK2_HUMAN
NC score	0.001381 (rank : 626)	θ value	6.88961 (rank : 501)
Query Neighborhood Hits	587	Target Neighborhood Hits	847	Shared Neighborhood Hits	28
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

M3K6_HUMAN
NC score	0.001284 (rank : 627)	θ value	5.27518 (rank : 462)
Query Neighborhood Hits	587	Target Neighborhood Hits	889	Shared Neighborhood Hits	38
SwissProt Accessions	O95382	Gene names	MAP3K6, MAPKKK6
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25).

MMP9_HUMAN
NC score	0.000740 (rank : 628)	θ value	8.99809 (rank : 563)
Query Neighborhood Hits	587	Target Neighborhood Hits	125	Shared Neighborhood Hits	15
SwissProt Accessions	P14780, Q3LR70, Q8N725, Q9H4Z1	Gene names	MMP9, CLG4B
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB) [Contains: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9].

CAD16_HUMAN
NC score	0.000643 (rank : 629)	θ value	8.99809 (rank : 535)
Query Neighborhood Hits	587	Target Neighborhood Hits	159	Shared Neighborhood Hits	9
SwissProt Accessions	O75309, Q6UW93	Gene names	CDH16
Domain Architecture
Description	Cadherin-16 precursor (Kidney-specific cadherin) (Ksp-cadherin).

MARK4_MOUSE
NC score	0.000633 (rank : 630)	θ value	5.27518 (rank : 463)
Query Neighborhood Hits	587	Target Neighborhood Hits	898	Shared Neighborhood Hits	41
SwissProt Accessions	Q8CIP4, Q80T81	Gene names	Mark4, Kiaa1860
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1).

DYR1B_HUMAN
NC score	0.000565 (rank : 631)	θ value	5.27518 (rank : 445)
Query Neighborhood Hits	587	Target Neighborhood Hits	831	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y463, O75258, O75788, O75789	Gene names	DYRK1B, MIRK
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Mirk protein kinase) (Minibrain-related kinase).

PCD12_HUMAN
NC score	0.000537 (rank : 632)	θ value	0.62314 (rank : 200)
Query Neighborhood Hits	587	Target Neighborhood Hits	203	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NPG4, Q6UXB6, Q96KB8, Q9H7Y6, Q9H8E0	Gene names	PCDH12
Domain Architecture
Description	Protocadherin-12 precursor (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cadherin-2) (VE-cad-2).

KCC2B_HUMAN
NC score	0.000526 (rank : 633)	θ value	5.27518 (rank : 459)
Query Neighborhood Hits	587	Target Neighborhood Hits	866	Shared Neighborhood Hits	37
SwissProt Accessions	Q13554, O95437, O95438, O95599, Q9UGH7, Q9UGH8, Q9UGH9, Q9UNX0, Q9UNX7, Q9UP00, Q9Y5N4, Q9Y6F4	Gene names	CAMK2B, CAM2, CAMKB
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II beta chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II subunit beta) (CaMK-II subunit beta).

M4K4_MOUSE
NC score	0.000203 (rank : 634)	θ value	4.03905 (rank : 412)
Query Neighborhood Hits	587	Target Neighborhood Hits	1560	Shared Neighborhood Hits	68
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MAK_MOUSE
NC score	-0.000130 (rank : 635)	θ value	4.03905 (rank : 414)
Query Neighborhood Hits	587	Target Neighborhood Hits	873	Shared Neighborhood Hits	36
SwissProt Accessions	Q04859	Gene names	Mak, Rck
Domain Architecture
Description	Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male germ cell- associated kinase) (Protein kinase RCK).

KLF2_HUMAN
NC score	-0.000578 (rank : 636)	θ value	1.38821 (rank : 266)
Query Neighborhood Hits	587	Target Neighborhood Hits	755	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y5W3, Q9UJS5, Q9UKR6	Gene names	KLF2, LKLF
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 2 (Lung krueppel-like factor).

SDK1_HUMAN
NC score	-0.000615 (rank : 637)	θ value	8.99809 (rank : 578)
Query Neighborhood Hits	587	Target Neighborhood Hits	511	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

KS6A3_MOUSE
NC score	-0.000845 (rank : 638)	θ value	4.03905 (rank : 410)
Query Neighborhood Hits	587	Target Neighborhood Hits	860	Shared Neighborhood Hits	28
SwissProt Accessions	P18654, Q03140, Q8K3J8	Gene names	Rps6ka3, Rps6ka-rs1, Rsk2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1) (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B).

KS6A3_HUMAN
NC score	-0.000853 (rank : 639)	θ value	4.03905 (rank : 409)
Query Neighborhood Hits	587	Target Neighborhood Hits	859	Shared Neighborhood Hits	28
SwissProt Accessions	P51812, Q4VAP3, Q59H26, Q5JPK8, Q7Z3Z7	Gene names	RPS6KA3, ISPK1, RSK2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1) (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B).

ZBT45_HUMAN
NC score	-0.001070 (rank : 640)	θ value	2.36792 (rank : 349)
Query Neighborhood Hits	587	Target Neighborhood Hits	901	Shared Neighborhood Hits	56
SwissProt Accessions	Q96K62	Gene names	ZBTB45, ZNF499
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 45 (Zinc finger protein 499).

SP2_HUMAN
NC score	-0.001602 (rank : 641)	θ value	1.38821 (rank : 272)
Query Neighborhood Hits	587	Target Neighborhood Hits	747	Shared Neighborhood Hits	32
SwissProt Accessions	Q02086	Gene names	SP2, KIAA0048
Domain Architecture
Description	Transcription factor Sp2.

GLI1_HUMAN
NC score	-0.001713 (rank : 642)	θ value	5.27518 (rank : 450)
Query Neighborhood Hits	587	Target Neighborhood Hits	828	Shared Neighborhood Hits	54
SwissProt Accessions	P08151, Q8TDN9	Gene names	GLI1, GLI
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI).

KLF2_MOUSE
NC score	-0.002511 (rank : 643)	θ value	3.0926 (rank : 371)
Query Neighborhood Hits	587	Target Neighborhood Hits	738	Shared Neighborhood Hits	30
SwissProt Accessions	Q60843	Gene names	Klf2, Lklf
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 2 (Lung krueppel-like factor).

MYH4_MOUSE
NC score	-0.002563 (rank : 644)	θ value	1.81305 (rank : 295)
Query Neighborhood Hits	587	Target Neighborhood Hits	1476	Shared Neighborhood Hits	56
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

ZN628_HUMAN
NC score	-0.003060 (rank : 645)	θ value	0.365318 (rank : 171)
Query Neighborhood Hits	587	Target Neighborhood Hits	814	Shared Neighborhood Hits	38
SwissProt Accessions	Q5EBL2, Q86X34	Gene names	ZNF628
Domain Architecture	No domain graphic available
Description	Zinc finger protein 628.

ZN628_MOUSE
NC score	-0.003140 (rank : 646)	θ value	1.38821 (rank : 278)
Query Neighborhood Hits	587	Target Neighborhood Hits	815	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CJ78, Q3U2L5, Q6P5B3	Gene names	Znf628, Zec, Zfp628
Domain Architecture	No domain graphic available
Description	Zinc finger protein 628 (Zinc finger protein expressed in embryonal cells and certain adult organs).

SP8_HUMAN
NC score	-0.003316 (rank : 647)	θ value	5.27518 (rank : 476)
Query Neighborhood Hits	587	Target Neighborhood Hits	714	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IXZ3, Q7Z616, Q96MJ1	Gene names	SP8
Domain Architecture	No domain graphic available
Description	Transcription factor Sp8 (Specificity protein 8).

MTF1_MOUSE
NC score	-0.003326 (rank : 648)	θ value	5.27518 (rank : 465)
Query Neighborhood Hits	587	Target Neighborhood Hits	785	Shared Neighborhood Hits	38
SwissProt Accessions	Q07243	Gene names	Mtf1, Mtf-1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

POLS2_MOUSE
NC score	-0.003820 (rank : 649)	θ value	8.99809 (rank : 572)
Query Neighborhood Hits	587	Target Neighborhood Hits	188	Shared Neighborhood Hits	2
SwissProt Accessions	Q5K2P8	Gene names	Prss36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

ZN236_HUMAN
NC score	-0.003997 (rank : 650)	θ value	6.88961 (rank : 531)
Query Neighborhood Hits	587	Target Neighborhood Hits	844	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UL36, Q9UL37	Gene names	ZNF236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 236.

ACM4_MOUSE
NC score	-0.007539 (rank : 651)	θ value	8.99809 (rank : 532)
Query Neighborhood Hits	587	Target Neighborhood Hits	894	Shared Neighborhood Hits	13
SwissProt Accessions	P32211, Q64056	Gene names	Chrm4, Chrm-4
Domain Architecture
Description	Muscarinic acetylcholine receptor M4 (Mm4 mAChR).

PAR4_HUMAN
NC score	-0.007744 (rank : 652)	θ value	6.88961 (rank : 512)
Query Neighborhood Hits	587	Target Neighborhood Hits	821	Shared Neighborhood Hits	3
SwissProt Accessions	Q96RI0, O76067, Q6DK42	Gene names	F2RL3, PAR4
Domain Architecture
Description	Proteinase-activated receptor 4 precursor (PAR-4) (Thrombin receptor- like 3) (Coagulation factor II receptor-like 3).