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Network neighborhood for query Sequence : KCNB2_HUMAN

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KCNB2_HUMAN
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

KCNB1_HUMAN
θ value	0 (rank : 1)	NC score	0.992590 (rank : 3)
Query Neighborhood Hits	212	Target Neighborhood Hits	169	Shared Neighborhood Hits	130
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNB1_MOUSE
θ value	0 (rank : 2)	NC score	0.992897 (rank : 2)
Query Neighborhood Hits	212	Target Neighborhood Hits	154	Shared Neighborhood Hits	131
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNB2_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	212	Target Neighborhood Hits	212	Shared Neighborhood Hits	212
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNS2_HUMAN
θ value	4.6295e-105 (rank : 4)	NC score	0.979376 (rank : 7)
Query Neighborhood Hits	212	Target Neighborhood Hits	129	Shared Neighborhood Hits	123
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_MOUSE
θ value	1.94503e-103 (rank : 5)	NC score	0.979406 (rank : 6)
Query Neighborhood Hits	212	Target Neighborhood Hits	130	Shared Neighborhood Hits	123
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS3_HUMAN
θ value	1.3939e-101 (rank : 6)	NC score	0.977532 (rank : 8)
Query Neighborhood Hits	212	Target Neighborhood Hits	125	Shared Neighborhood Hits	111
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

KCNS1_HUMAN
θ value	7.91507e-97 (rank : 7)	NC score	0.975929 (rank : 9)
Query Neighborhood Hits	212	Target Neighborhood Hits	116	Shared Neighborhood Hits	109
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNF1_HUMAN
θ value	4.06505e-93 (rank : 8)	NC score	0.979702 (rank : 4)
Query Neighborhood Hits	212	Target Neighborhood Hits	109	Shared Neighborhood Hits	103
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCNV2_HUMAN
θ value	1.70789e-91 (rank : 9)	NC score	0.979574 (rank : 5)
Query Neighborhood Hits	212	Target Neighborhood Hits	137	Shared Neighborhood Hits	118
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCNG1_HUMAN
θ value	1.88829e-90 (rank : 10)	NC score	0.968667 (rank : 11)
Query Neighborhood Hits	212	Target Neighborhood Hits	103	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNG4_HUMAN
θ value	2.30828e-88 (rank : 11)	NC score	0.964436 (rank : 14)
Query Neighborhood Hits	212	Target Neighborhood Hits	99	Shared Neighborhood Hits	90
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNS1_MOUSE
θ value	2.5521e-87 (rank : 12)	NC score	0.972482 (rank : 10)
Query Neighborhood Hits	212	Target Neighborhood Hits	114	Shared Neighborhood Hits	104
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNG2_HUMAN
θ value	2.47191e-82 (rank : 13)	NC score	0.963261 (rank : 15)
Query Neighborhood Hits	212	Target Neighborhood Hits	83	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNG3_MOUSE
θ value	3.12697e-77 (rank : 14)	NC score	0.966239 (rank : 12)
Query Neighborhood Hits	212	Target Neighborhood Hits	91	Shared Neighborhood Hits	90
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNG3_HUMAN
θ value	5.33382e-77 (rank : 15)	NC score	0.965805 (rank : 13)
Query Neighborhood Hits	212	Target Neighborhood Hits	91	Shared Neighborhood Hits	88
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNC1_HUMAN
θ value	5.51964e-74 (rank : 16)	NC score	0.953494 (rank : 16)
Query Neighborhood Hits	212	Target Neighborhood Hits	133	Shared Neighborhood Hits	119
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC1_MOUSE
θ value	7.20884e-74 (rank : 17)	NC score	0.953313 (rank : 17)
Query Neighborhood Hits	212	Target Neighborhood Hits	133	Shared Neighborhood Hits	119
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC4_HUMAN
θ value	1.7756e-72 (rank : 18)	NC score	0.949214 (rank : 18)
Query Neighborhood Hits	212	Target Neighborhood Hits	141	Shared Neighborhood Hits	116
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KCNC4_MOUSE
θ value	2.56397e-71 (rank : 19)	NC score	0.948678 (rank : 19)
Query Neighborhood Hits	212	Target Neighborhood Hits	130	Shared Neighborhood Hits	115
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCND2_MOUSE
θ value	5.91091e-68 (rank : 20)	NC score	0.943077 (rank : 21)
Query Neighborhood Hits	212	Target Neighborhood Hits	156	Shared Neighborhood Hits	130
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_HUMAN
θ value	7.71989e-68 (rank : 21)	NC score	0.943083 (rank : 20)
Query Neighborhood Hits	212	Target Neighborhood Hits	154	Shared Neighborhood Hits	130
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCNA1_MOUSE
θ value	6.53529e-67 (rank : 22)	NC score	0.937655 (rank : 26)
Query Neighborhood Hits	212	Target Neighborhood Hits	103	Shared Neighborhood Hits	95
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNA1_HUMAN
θ value	8.53533e-67 (rank : 23)	NC score	0.937309 (rank : 27)
Query Neighborhood Hits	212	Target Neighborhood Hits	104	Shared Neighborhood Hits	94
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCND3_HUMAN
θ value	1.2325e-65 (rank : 24)	NC score	0.941515 (rank : 23)
Query Neighborhood Hits	212	Target Neighborhood Hits	162	Shared Neighborhood Hits	130
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_MOUSE
θ value	1.2325e-65 (rank : 25)	NC score	0.941964 (rank : 22)
Query Neighborhood Hits	212	Target Neighborhood Hits	162	Shared Neighborhood Hits	130
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND1_MOUSE
θ value	1.04338e-64 (rank : 26)	NC score	0.940390 (rank : 25)
Query Neighborhood Hits	212	Target Neighborhood Hits	165	Shared Neighborhood Hits	129
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCNA2_HUMAN
θ value	1.77973e-64 (rank : 27)	NC score	0.934078 (rank : 30)
Query Neighborhood Hits	212	Target Neighborhood Hits	101	Shared Neighborhood Hits	92
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNA2_MOUSE
θ value	2.32439e-64 (rank : 28)	NC score	0.934298 (rank : 29)
Query Neighborhood Hits	212	Target Neighborhood Hits	102	Shared Neighborhood Hits	93
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCND1_HUMAN
θ value	2.32439e-64 (rank : 29)	NC score	0.940931 (rank : 24)
Query Neighborhood Hits	212	Target Neighborhood Hits	160	Shared Neighborhood Hits	128
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCNA4_HUMAN
θ value	1.15359e-63 (rank : 30)	NC score	0.932792 (rank : 35)
Query Neighborhood Hits	212	Target Neighborhood Hits	108	Shared Neighborhood Hits	89
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNA3_HUMAN
θ value	4.38363e-63 (rank : 31)	NC score	0.934477 (rank : 28)
Query Neighborhood Hits	212	Target Neighborhood Hits	101	Shared Neighborhood Hits	90
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNA3_MOUSE
θ value	7.47731e-63 (rank : 32)	NC score	0.933903 (rank : 32)
Query Neighborhood Hits	212	Target Neighborhood Hits	103	Shared Neighborhood Hits	90
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCNA4_MOUSE
θ value	2.84138e-62 (rank : 33)	NC score	0.932878 (rank : 34)
Query Neighborhood Hits	212	Target Neighborhood Hits	98	Shared Neighborhood Hits	85
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNA5_HUMAN
θ value	4.24587e-58 (rank : 34)	NC score	0.931258 (rank : 38)
Query Neighborhood Hits	212	Target Neighborhood Hits	124	Shared Neighborhood Hits	89
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNA6_HUMAN
θ value	2.7521e-57 (rank : 35)	NC score	0.933568 (rank : 33)
Query Neighborhood Hits	212	Target Neighborhood Hits	100	Shared Neighborhood Hits	92
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNA5_MOUSE
θ value	4.69435e-57 (rank : 36)	NC score	0.931696 (rank : 37)
Query Neighborhood Hits	212	Target Neighborhood Hits	119	Shared Neighborhood Hits	93
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCNA6_MOUSE
θ value	1.15626e-55 (rank : 37)	NC score	0.933977 (rank : 31)
Query Neighborhood Hits	212	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNC3_MOUSE
θ value	9.48078e-50 (rank : 38)	NC score	0.932190 (rank : 36)
Query Neighborhood Hits	212	Target Neighborhood Hits	173	Shared Neighborhood Hits	113
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC3_HUMAN
θ value	3.60269e-49 (rank : 39)	NC score	0.930194 (rank : 39)
Query Neighborhood Hits	212	Target Neighborhood Hits	256	Shared Neighborhood Hits	121
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNQ5_HUMAN
θ value	4.29542e-18 (rank : 40)	NC score	0.713352 (rank : 44)
Query Neighborhood Hits	212	Target Neighborhood Hits	163	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

KCNQ4_HUMAN
θ value	1.24977e-17 (rank : 41)	NC score	0.712824 (rank : 45)
Query Neighborhood Hits	212	Target Neighborhood Hits	136	Shared Neighborhood Hits	87
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCNQ1_HUMAN
θ value	2.13179e-17 (rank : 42)	NC score	0.751155 (rank : 40)
Query Neighborhood Hits	212	Target Neighborhood Hits	99	Shared Neighborhood Hits	77
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ1_MOUSE
θ value	8.10077e-17 (rank : 43)	NC score	0.744456 (rank : 41)
Query Neighborhood Hits	212	Target Neighborhood Hits	175	Shared Neighborhood Hits	81
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ2_HUMAN
θ value	1.058e-16 (rank : 44)	NC score	0.721634 (rank : 42)
Query Neighborhood Hits	212	Target Neighborhood Hits	114	Shared Neighborhood Hits	77
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ2_MOUSE
θ value	5.25075e-16 (rank : 45)	NC score	0.719692 (rank : 43)
Query Neighborhood Hits	212	Target Neighborhood Hits	163	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ3_HUMAN
θ value	6.41864e-14 (rank : 46)	NC score	0.680859 (rank : 47)
Query Neighborhood Hits	212	Target Neighborhood Hits	114	Shared Neighborhood Hits	79
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_MOUSE
θ value	6.41864e-14 (rank : 47)	NC score	0.681673 (rank : 46)
Query Neighborhood Hits	212	Target Neighborhood Hits	105	Shared Neighborhood Hits	78
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCMA1_HUMAN
θ value	1.63604e-09 (rank : 48)	NC score	0.492745 (rank : 49)
Query Neighborhood Hits	212	Target Neighborhood Hits	96	Shared Neighborhood Hits	73
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

KCMA1_MOUSE
θ value	1.63604e-09 (rank : 49)	NC score	0.493651 (rank : 48)
Query Neighborhood Hits	212	Target Neighborhood Hits	94	Shared Neighborhood Hits	73
SwissProt Accessions	Q08460, Q64703, Q8VHF1, Q9R196	Gene names	Kcnma1, Kcnma
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (mSlo) (mSlo1).

SCN3A_HUMAN
θ value	3.41135e-07 (rank : 50)	NC score	0.217044 (rank : 86)
Query Neighborhood Hits	212	Target Neighborhood Hits	115	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

CAC1C_MOUSE
θ value	4.45536e-07 (rank : 51)	NC score	0.216935 (rank : 87)
Query Neighborhood Hits	212	Target Neighborhood Hits	130	Shared Neighborhood Hits	59
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

SCN2A_HUMAN
θ value	1.69304e-06 (rank : 52)	NC score	0.208000 (rank : 100)
Query Neighborhood Hits	212	Target Neighborhood Hits	157	Shared Neighborhood Hits	54
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

CAC1D_HUMAN
θ value	4.92598e-06 (rank : 53)	NC score	0.225777 (rank : 77)
Query Neighborhood Hits	212	Target Neighborhood Hits	118	Shared Neighborhood Hits	61
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CAC1I_HUMAN
θ value	4.92598e-06 (rank : 54)	NC score	0.255048 (rank : 68)
Query Neighborhood Hits	212	Target Neighborhood Hits	138	Shared Neighborhood Hits	64
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

CAC1H_HUMAN
θ value	1.09739e-05 (rank : 55)	NC score	0.252145 (rank : 70)
Query Neighborhood Hits	212	Target Neighborhood Hits	307	Shared Neighborhood Hits	67
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

SCN1A_HUMAN
θ value	1.09739e-05 (rank : 56)	NC score	0.209533 (rank : 98)
Query Neighborhood Hits	212	Target Neighborhood Hits	148	Shared Neighborhood Hits	54
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

CAC1H_MOUSE
θ value	1.43324e-05 (rank : 57)	NC score	0.256258 (rank : 67)
Query Neighborhood Hits	212	Target Neighborhood Hits	230	Shared Neighborhood Hits	69
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CAC1S_HUMAN
θ value	4.1701e-05 (rank : 58)	NC score	0.214094 (rank : 92)
Query Neighborhood Hits	212	Target Neighborhood Hits	92	Shared Neighborhood Hits	55
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

SC11A_HUMAN
θ value	4.1701e-05 (rank : 59)	NC score	0.265451 (rank : 64)
Query Neighborhood Hits	212	Target Neighborhood Hits	111	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

SCN4A_HUMAN
θ value	5.44631e-05 (rank : 60)	NC score	0.248805 (rank : 71)
Query Neighborhood Hits	212	Target Neighborhood Hits	133	Shared Neighborhood Hits	71
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

SCN9A_HUMAN
θ value	9.29e-05 (rank : 61)	NC score	0.216165 (rank : 90)
Query Neighborhood Hits	212	Target Neighborhood Hits	157	Shared Neighborhood Hits	57
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

SC10A_MOUSE
θ value	0.000158464 (rank : 62)	NC score	0.222576 (rank : 79)
Query Neighborhood Hits	212	Target Neighborhood Hits	107	Shared Neighborhood Hits	58
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

KCNN4_HUMAN
θ value	0.00020696 (rank : 63)	NC score	0.353230 (rank : 51)
Query Neighborhood Hits	212	Target Neighborhood Hits	90	Shared Neighborhood Hits	68
SwissProt Accessions	O15554	Gene names	KCNN4, IK1, IKCA1, KCA4, SK4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1) (IKCa1) (Putative Gardos channel).

KCNN4_MOUSE
θ value	0.00020696 (rank : 64)	NC score	0.354904 (rank : 50)
Query Neighborhood Hits	212	Target Neighborhood Hits	85	Shared Neighborhood Hits	68
SwissProt Accessions	O89109, Q3U1J8, Q9CY39	Gene names	Kcnn4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1).

SCN8A_HUMAN
θ value	0.000270298 (rank : 65)	NC score	0.213500 (rank : 95)
Query Neighborhood Hits	212	Target Neighborhood Hits	135	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN8A_MOUSE
θ value	0.000270298 (rank : 66)	NC score	0.213705 (rank : 93)
Query Neighborhood Hits	212	Target Neighborhood Hits	136	Shared Neighborhood Hits	57
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SC10A_HUMAN
θ value	0.000461057 (rank : 67)	NC score	0.210427 (rank : 97)
Query Neighborhood Hits	212	Target Neighborhood Hits	116	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

KCTD2_HUMAN
θ value	0.000786445 (rank : 68)	NC score	0.285910 (rank : 56)
Query Neighborhood Hits	212	Target Neighborhood Hits	69	Shared Neighborhood Hits	50
SwissProt Accessions	Q14681	Gene names	KCTD2, KIAA0176
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD2.

CAC1C_HUMAN
θ value	0.00102713 (rank : 69)	NC score	0.206996 (rank : 101)
Query Neighborhood Hits	212	Target Neighborhood Hits	158	Shared Neighborhood Hits	59
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

SCN5A_HUMAN
θ value	0.00102713 (rank : 70)	NC score	0.215547 (rank : 91)
Query Neighborhood Hits	212	Target Neighborhood Hits	145	Shared Neighborhood Hits	56
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

CAC1G_HUMAN
θ value	0.00134147 (rank : 71)	NC score	0.224058 (rank : 78)
Query Neighborhood Hits	212	Target Neighborhood Hits	587	Shared Neighborhood Hits	76
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

KCTD1_HUMAN
θ value	0.00228821 (rank : 72)	NC score	0.296232 (rank : 52)
Query Neighborhood Hits	212	Target Neighborhood Hits	74	Shared Neighborhood Hits	61
SwissProt Accessions	Q719H9	Gene names	KCTD1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD1.

KCTD1_MOUSE
θ value	0.00228821 (rank : 73)	NC score	0.296232 (rank : 53)
Query Neighborhood Hits	212	Target Neighborhood Hits	74	Shared Neighborhood Hits	61
SwissProt Accessions	Q5M956, Q5EER9	Gene names	Kctd1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD1.

SC11A_MOUSE
θ value	0.00228821 (rank : 74)	NC score	0.248746 (rank : 72)
Query Neighborhood Hits	212	Target Neighborhood Hits	116	Shared Neighborhood Hits	67
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

CAC1S_MOUSE
θ value	0.00298849 (rank : 75)	NC score	0.209465 (rank : 99)
Query Neighborhood Hits	212	Target Neighborhood Hits	98	Shared Neighborhood Hits	58
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

KCNN1_HUMAN
θ value	0.00390308 (rank : 76)	NC score	0.279277 (rank : 60)
Query Neighborhood Hits	212	Target Neighborhood Hits	125	Shared Neighborhood Hits	67
SwissProt Accessions	Q92952	Gene names	KCNN1, SK
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 1 (SK1).

KCNN1_MOUSE
θ value	0.00390308 (rank : 77)	NC score	0.280444 (rank : 59)
Query Neighborhood Hits	212	Target Neighborhood Hits	117	Shared Neighborhood Hits	69
SwissProt Accessions	Q9EQR3, Q99JA9	Gene names	Kcnn1, Sk1
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 1 (SK1).

KCTD5_HUMAN
θ value	0.00390308 (rank : 78)	NC score	0.264366 (rank : 65)
Query Neighborhood Hits	212	Target Neighborhood Hits	66	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NXV2	Gene names	KCTD5
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD5.

KCTD5_MOUSE
θ value	0.00509761 (rank : 79)	NC score	0.265661 (rank : 62)
Query Neighborhood Hits	212	Target Neighborhood Hits	64	Shared Neighborhood Hits	50
SwissProt Accessions	Q8VC57	Gene names	Kctd5
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD5.

KCNN2_HUMAN
θ value	0.00665767 (rank : 80)	NC score	0.288071 (rank : 54)
Query Neighborhood Hits	212	Target Neighborhood Hits	117	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H2S1	Gene names	KCNN2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KCNN2_MOUSE
θ value	0.00665767 (rank : 81)	NC score	0.288058 (rank : 55)
Query Neighborhood Hits	212	Target Neighborhood Hits	120	Shared Neighborhood Hits	67
SwissProt Accessions	P58390	Gene names	Kcnn2, Sk2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KCNN3_HUMAN
θ value	0.00869519 (rank : 82)	NC score	0.282993 (rank : 57)
Query Neighborhood Hits	212	Target Neighborhood Hits	216	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UGI6, O43517	Gene names	KCNN3, K3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3) (SKCa3).

KCNN3_MOUSE
θ value	0.00869519 (rank : 83)	NC score	0.281574 (rank : 58)
Query Neighborhood Hits	212	Target Neighborhood Hits	171	Shared Neighborhood Hits	71
SwissProt Accessions	P58391	Gene names	Kcnn3, Sk3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3).

PRG4_HUMAN
θ value	0.00869519 (rank : 84)	NC score	0.019915 (rank : 151)
Query Neighborhood Hits	212	Target Neighborhood Hits	764	Shared Neighborhood Hits	33
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

ACINU_MOUSE
θ value	0.0148317 (rank : 85)	NC score	0.020049 (rank : 149)
Query Neighborhood Hits	212	Target Neighborhood Hits	712	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

CAC1B_MOUSE
θ value	0.0148317 (rank : 86)	NC score	0.218013 (rank : 85)
Query Neighborhood Hits	212	Target Neighborhood Hits	351	Shared Neighborhood Hits	71
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1F_HUMAN
θ value	0.0148317 (rank : 87)	NC score	0.220106 (rank : 84)
Query Neighborhood Hits	212	Target Neighborhood Hits	141	Shared Neighborhood Hits	61
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1F_MOUSE
θ value	0.0148317 (rank : 88)	NC score	0.220991 (rank : 82)
Query Neighborhood Hits	212	Target Neighborhood Hits	142	Shared Neighborhood Hits	61
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1A_HUMAN
θ value	0.0193708 (rank : 89)	NC score	0.216692 (rank : 89)
Query Neighborhood Hits	212	Target Neighborhood Hits	387	Shared Neighborhood Hits	75
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1A_MOUSE
θ value	0.0193708 (rank : 90)	NC score	0.216754 (rank : 88)
Query Neighborhood Hits	212	Target Neighborhood Hits	267	Shared Neighborhood Hits	73
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CMTA2_MOUSE
θ value	0.0252991 (rank : 91)	NC score	0.023120 (rank : 145)
Query Neighborhood Hits	212	Target Neighborhood Hits	216	Shared Neighborhood Hits	9
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

KCNT1_HUMAN
θ value	0.0252991 (rank : 92)	NC score	0.229336 (rank : 76)
Query Neighborhood Hits	212	Target Neighborhood Hits	87	Shared Neighborhood Hits	66
SwissProt Accessions	Q5JUK3, Q9P2C5	Gene names	KCNT1, KIAA1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1 (KCa4.1).

SI1L1_MOUSE
θ value	0.0330416 (rank : 93)	NC score	0.020748 (rank : 147)
Query Neighborhood Hits	212	Target Neighborhood Hits	189	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

CAC1B_HUMAN
θ value	0.0431538 (rank : 94)	NC score	0.210969 (rank : 96)
Query Neighborhood Hits	212	Target Neighborhood Hits	257	Shared Neighborhood Hits	60
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

E2F4_HUMAN
θ value	0.0431538 (rank : 95)	NC score	0.021779 (rank : 146)
Query Neighborhood Hits	212	Target Neighborhood Hits	188	Shared Neighborhood Hits	8
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

SCN7A_HUMAN
θ value	0.0563607 (rank : 96)	NC score	0.197786 (rank : 106)
Query Neighborhood Hits	212	Target Neighborhood Hits	135	Shared Neighborhood Hits	62
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

CAC1E_HUMAN
θ value	0.0736092 (rank : 97)	NC score	0.203431 (rank : 105)
Query Neighborhood Hits	212	Target Neighborhood Hits	148	Shared Neighborhood Hits	58
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_MOUSE
θ value	0.0736092 (rank : 98)	NC score	0.203732 (rank : 104)
Query Neighborhood Hits	212	Target Neighborhood Hits	167	Shared Neighborhood Hits	56
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

KCD17_HUMAN
θ value	0.0736092 (rank : 99)	NC score	0.213570 (rank : 94)
Query Neighborhood Hits	212	Target Neighborhood Hits	85	Shared Neighborhood Hits	47
SwissProt Accessions	Q8N5Z5, O95517	Gene names	KCTD17
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD17.

PDZD2_HUMAN
θ value	0.0736092 (rank : 100)	NC score	0.016396 (rank : 157)
Query Neighborhood Hits	212	Target Neighborhood Hits	772	Shared Neighborhood Hits	33
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

SI1L1_HUMAN
θ value	0.0961366 (rank : 101)	NC score	0.019915 (rank : 150)
Query Neighborhood Hits	212	Target Neighborhood Hits	162	Shared Neighborhood Hits	5
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

FES_HUMAN
θ value	0.125558 (rank : 102)	NC score	-0.003348 (rank : 216)
Query Neighborhood Hits	212	Target Neighborhood Hits	978	Shared Neighborhood Hits	9
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

TCOF_HUMAN
θ value	0.125558 (rank : 103)	NC score	0.020657 (rank : 148)
Query Neighborhood Hits	212	Target Neighborhood Hits	543	Shared Neighborhood Hits	25
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

KCD14_HUMAN
θ value	0.21417 (rank : 104)	NC score	0.179949 (rank : 108)
Query Neighborhood Hits	212	Target Neighborhood Hits	59	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BQ13	Gene names	KCTD14
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD14.

KCD15_HUMAN
θ value	0.21417 (rank : 105)	NC score	0.277791 (rank : 61)
Query Neighborhood Hits	212	Target Neighborhood Hits	76	Shared Neighborhood Hits	61
SwissProt Accessions	Q96SI1, Q9BVI6	Gene names	KCTD15
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD15.

SRRM2_MOUSE
θ value	0.21417 (rank : 106)	NC score	0.018799 (rank : 152)
Query Neighborhood Hits	212	Target Neighborhood Hits	1470	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

BTBDC_HUMAN
θ value	0.279714 (rank : 107)	NC score	0.025913 (rank : 143)
Query Neighborhood Hits	212	Target Neighborhood Hits	248	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

CENPC_HUMAN
θ value	0.279714 (rank : 108)	NC score	0.018587 (rank : 153)
Query Neighborhood Hits	212	Target Neighborhood Hits	147	Shared Neighborhood Hits	4
SwissProt Accessions	Q03188, Q9P0M5	Gene names	CENPC1, CENPC, ICEN7
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C) (Interphase centromere complex protein 7).

KCNKA_HUMAN
θ value	0.279714 (rank : 109)	NC score	0.204138 (rank : 103)
Query Neighborhood Hits	212	Target Neighborhood Hits	111	Shared Neighborhood Hits	77
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

KCNKH_HUMAN
θ value	0.365318 (rank : 110)	NC score	0.177716 (rank : 109)
Query Neighborhood Hits	212	Target Neighborhood Hits	89	Shared Neighborhood Hits	70
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

SFRS4_MOUSE
θ value	0.365318 (rank : 111)	NC score	0.008382 (rank : 172)
Query Neighborhood Hits	212	Target Neighborhood Hits	406	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

KCNRG_HUMAN
θ value	0.47712 (rank : 112)	NC score	0.222349 (rank : 80)
Query Neighborhood Hits	212	Target Neighborhood Hits	68	Shared Neighborhood Hits	54
SwissProt Accessions	Q8N5I3, Q8IU75, Q8N3Q9	Gene names	KCNRG, CLLD4
Domain Architecture	No domain graphic available
Description	Putative potassium channel regulatory protein (Potassium channel regulator) (Protein CLLD4).

LAP4_MOUSE
θ value	0.47712 (rank : 113)	NC score	0.001022 (rank : 208)
Query Neighborhood Hits	212	Target Neighborhood Hits	590	Shared Neighborhood Hits	11
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

RECQ4_MOUSE
θ value	0.47712 (rank : 114)	NC score	0.009895 (rank : 169)
Query Neighborhood Hits	212	Target Neighborhood Hits	206	Shared Neighborhood Hits	7
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

M3K14_MOUSE
θ value	0.62314 (rank : 115)	NC score	-0.003574 (rank : 217)
Query Neighborhood Hits	212	Target Neighborhood Hits	889	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WUL6	Gene names	Map3k14, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK).

VGF_HUMAN
θ value	0.62314 (rank : 116)	NC score	0.025036 (rank : 144)
Query Neighborhood Hits	212	Target Neighborhood Hits	167	Shared Neighborhood Hits	12
SwissProt Accessions	O15240	Gene names	VGF
Domain Architecture	No domain graphic available
Description	Neurosecretory protein VGF precursor.

FES_MOUSE
θ value	0.813845 (rank : 117)	NC score	-0.003954 (rank : 218)
Query Neighborhood Hits	212	Target Neighborhood Hits	980	Shared Neighborhood Hits	6
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

KCNH6_HUMAN
θ value	0.813845 (rank : 118)	NC score	0.031826 (rank : 142)
Query Neighborhood Hits	212	Target Neighborhood Hits	222	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNK4_MOUSE
θ value	0.813845 (rank : 119)	NC score	0.087966 (rank : 128)
Query Neighborhood Hits	212	Target Neighborhood Hits	118	Shared Neighborhood Hits	55
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

KI67_HUMAN
θ value	0.813845 (rank : 120)	NC score	0.018232 (rank : 154)
Query Neighborhood Hits	212	Target Neighborhood Hits	581	Shared Neighborhood Hits	24
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

SON_MOUSE
θ value	0.813845 (rank : 121)	NC score	0.013788 (rank : 162)
Query Neighborhood Hits	212	Target Neighborhood Hits	957	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

CBL_HUMAN
θ value	1.06291 (rank : 122)	NC score	0.007772 (rank : 178)
Query Neighborhood Hits	212	Target Neighborhood Hits	353	Shared Neighborhood Hits	11
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

DNL3_HUMAN
θ value	1.06291 (rank : 123)	NC score	0.013315 (rank : 163)
Query Neighborhood Hits	212	Target Neighborhood Hits	49	Shared Neighborhood Hits	7
SwissProt Accessions	P49916, Q16714	Gene names	LIG3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

FA21C_HUMAN
θ value	1.06291 (rank : 124)	NC score	0.016022 (rank : 158)
Query Neighborhood Hits	212	Target Neighborhood Hits	194	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

FETUB_HUMAN
θ value	1.06291 (rank : 125)	NC score	0.013896 (rank : 161)
Query Neighborhood Hits	212	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UGM5, Q1RMZ0, Q6DK58, Q6GRB6, Q9Y6Z0	Gene names	FETUB
Domain Architecture
Description	Fetuin-B precursor (Gugu) (IRL685) (16G2).

KCD15_MOUSE
θ value	1.06291 (rank : 126)	NC score	0.265542 (rank : 63)
Query Neighborhood Hits	212	Target Neighborhood Hits	78	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K0E1	Gene names	Kctd15
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD15.

KCNK2_HUMAN
θ value	1.06291 (rank : 127)	NC score	0.130662 (rank : 120)
Query Neighborhood Hits	212	Target Neighborhood Hits	86	Shared Neighborhood Hits	66
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNK2_MOUSE
θ value	1.06291 (rank : 128)	NC score	0.133867 (rank : 119)
Query Neighborhood Hits	212	Target Neighborhood Hits	88	Shared Neighborhood Hits	67
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCTD3_HUMAN
θ value	1.06291 (rank : 129)	NC score	0.233280 (rank : 75)
Query Neighborhood Hits	212	Target Neighborhood Hits	90	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y597, Q49AG7, Q504Q9, Q6PJN6, Q8ND58, Q8NDJ0, Q8WX16	Gene names	KCTD3
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD3 (NY-REN-45 antigen).

KCTD3_MOUSE
θ value	1.06291 (rank : 130)	NC score	0.220332 (rank : 83)
Query Neighborhood Hits	212	Target Neighborhood Hits	85	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BFX3, Q6P7X4	Gene names	Kctd3
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD3.

MDC1_HUMAN
θ value	1.06291 (rank : 131)	NC score	0.014612 (rank : 159)
Query Neighborhood Hits	212	Target Neighborhood Hits	1446	Shared Neighborhood Hits	45
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

RGS3_MOUSE
θ value	1.06291 (rank : 132)	NC score	0.007837 (rank : 177)
Query Neighborhood Hits	212	Target Neighborhood Hits	1621	Shared Neighborhood Hits	53
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

AHTF1_HUMAN
θ value	1.38821 (rank : 133)	NC score	0.011250 (rank : 166)
Query Neighborhood Hits	212	Target Neighborhood Hits	286	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WYP5, Q7Z4E3, Q8IZA4, Q96EH9, Q9Y4Q6	Gene names	AHCTF1, ELYS, TMBS62
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

KCTD2_MOUSE
θ value	1.38821 (rank : 134)	NC score	0.139729 (rank : 116)
Query Neighborhood Hits	212	Target Neighborhood Hits	55	Shared Neighborhood Hits	42
SwissProt Accessions	Q8CEZ0	Gene names	Kctd2
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD2.

KCTD7_MOUSE
θ value	1.38821 (rank : 135)	NC score	0.222028 (rank : 81)
Query Neighborhood Hits	212	Target Neighborhood Hits	69	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BJK1, Q3USA6, Q8C0S7	Gene names	Kctd7
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD7.

SRRM2_HUMAN
θ value	1.38821 (rank : 136)	NC score	0.017778 (rank : 155)
Query Neighborhood Hits	212	Target Neighborhood Hits	1296	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

ZBT45_HUMAN
θ value	1.38821 (rank : 137)	NC score	-0.005950 (rank : 221)
Query Neighborhood Hits	212	Target Neighborhood Hits	901	Shared Neighborhood Hits	10
SwissProt Accessions	Q96K62	Gene names	ZBTB45, ZNF499
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 45 (Zinc finger protein 499).

AATK_MOUSE
θ value	1.81305 (rank : 138)	NC score	-0.002457 (rank : 214)
Query Neighborhood Hits	212	Target Neighborhood Hits	942	Shared Neighborhood Hits	17
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

ESX1L_HUMAN
θ value	1.81305 (rank : 139)	NC score	-0.001316 (rank : 213)
Query Neighborhood Hits	212	Target Neighborhood Hits	498	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N693, Q7Z6K7	Gene names	ESX1L, ESX1R
Domain Architecture
Description	Extraembryonic, spermatogenesis, homeobox 1-like protein.

GP179_HUMAN
θ value	1.81305 (rank : 140)	NC score	0.013939 (rank : 160)
Query Neighborhood Hits	212	Target Neighborhood Hits	372	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

GSCR1_HUMAN
θ value	1.81305 (rank : 141)	NC score	0.012609 (rank : 165)
Query Neighborhood Hits	212	Target Neighborhood Hits	674	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

KCNKF_HUMAN
θ value	1.81305 (rank : 142)	NC score	0.167410 (rank : 110)
Query Neighborhood Hits	212	Target Neighborhood Hits	87	Shared Neighborhood Hits	69
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

PTPRF_HUMAN
θ value	1.81305 (rank : 143)	NC score	-0.002644 (rank : 215)
Query Neighborhood Hits	212	Target Neighborhood Hits	489	Shared Neighborhood Hits	2
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

T2R41_HUMAN
θ value	1.81305 (rank : 144)	NC score	0.002548 (rank : 204)
Query Neighborhood Hits	212	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	P59536, P59550	Gene names	TAS2R41
Domain Architecture
Description	Taste receptor type 2 member 41 (T2R41) (T2R59).

ANLN_HUMAN
θ value	2.36792 (rank : 145)	NC score	0.009256 (rank : 170)
Query Neighborhood Hits	212	Target Neighborhood Hits	222	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

KCNT1_MOUSE
θ value	2.36792 (rank : 146)	NC score	0.140791 (rank : 115)
Query Neighborhood Hits	212	Target Neighborhood Hits	69	Shared Neighborhood Hits	52
SwissProt Accessions	Q6ZPR4, Q8C3E7	Gene names	Kcnt1, Kiaa1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1.

SFPQ_HUMAN
θ value	2.36792 (rank : 147)	NC score	0.003577 (rank : 197)
Query Neighborhood Hits	212	Target Neighborhood Hits	986	Shared Neighborhood Hits	26
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

ABCC8_HUMAN
θ value	3.0926 (rank : 148)	NC score	0.004943 (rank : 192)
Query Neighborhood Hits	212	Target Neighborhood Hits	118	Shared Neighborhood Hits	6
SwissProt Accessions	Q09428, O75948, Q16583	Gene names	ABCC8, SUR, SUR1
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 8 (Sulfonylurea receptor 1).

ECM1_HUMAN
θ value	3.0926 (rank : 149)	NC score	0.010263 (rank : 168)
Query Neighborhood Hits	212	Target Neighborhood Hits	182	Shared Neighborhood Hits	11
SwissProt Accessions	Q16610	Gene names	ECM1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

KCNH1_HUMAN
θ value	3.0926 (rank : 150)	NC score	0.043072 (rank : 140)
Query Neighborhood Hits	212	Target Neighborhood Hits	98	Shared Neighborhood Hits	37
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH1_MOUSE
θ value	3.0926 (rank : 151)	NC score	0.043103 (rank : 139)
Query Neighborhood Hits	212	Target Neighborhood Hits	94	Shared Neighborhood Hits	37
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNKG_HUMAN
θ value	3.0926 (rank : 152)	NC score	0.151484 (rank : 113)
Query Neighborhood Hits	212	Target Neighborhood Hits	90	Shared Neighborhood Hits	73
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

LRRF1_MOUSE
θ value	3.0926 (rank : 153)	NC score	0.006044 (rank : 184)
Query Neighborhood Hits	212	Target Neighborhood Hits	440	Shared Neighborhood Hits	14
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

MEGF9_HUMAN
θ value	3.0926 (rank : 154)	NC score	-0.000474 (rank : 212)
Query Neighborhood Hits	212	Target Neighborhood Hits	557	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MIER1_HUMAN
θ value	3.0926 (rank : 155)	NC score	0.008213 (rank : 174)
Query Neighborhood Hits	212	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N108, Q5T104, Q6AHY8, Q86TB4, Q8N156, Q8N161, Q8NC37, Q8NES4, Q8NES5, Q8NES6, Q8WWG2, Q9HCG2	Gene names	MIER1, KIAA1610
Domain Architecture	No domain graphic available
Description	Mesoderm induction early response protein 1 (Mi-er1) (hmi-er1) (Early response 1) (Er1).

MLL4_HUMAN
θ value	3.0926 (rank : 156)	NC score	0.005926 (rank : 185)
Query Neighborhood Hits	212	Target Neighborhood Hits	722	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

P3H3_MOUSE
θ value	3.0926 (rank : 157)	NC score	0.005644 (rank : 189)
Query Neighborhood Hits	212	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CG70, O88836	Gene names	Leprel2, P3h3
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 3 precursor (EC 1.14.11.7) (Leprecan-like protein 2) (Protein B).

PCLO_MOUSE
θ value	3.0926 (rank : 158)	NC score	0.005128 (rank : 191)
Query Neighborhood Hits	212	Target Neighborhood Hits	2275	Shared Neighborhood Hits	55
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

ELOA1_MOUSE
θ value	4.03905 (rank : 159)	NC score	0.006584 (rank : 183)
Query Neighborhood Hits	212	Target Neighborhood Hits	152	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CB77, Q80VB2, Q9R0Q5	Gene names	Tceb3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

HTSF1_MOUSE
θ value	4.03905 (rank : 160)	NC score	0.005306 (rank : 190)
Query Neighborhood Hits	212	Target Neighborhood Hits	425	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

KCNH5_HUMAN
θ value	4.03905 (rank : 161)	NC score	0.043655 (rank : 138)
Query Neighborhood Hits	212	Target Neighborhood Hits	99	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH5_MOUSE
θ value	4.03905 (rank : 162)	NC score	0.043672 (rank : 137)
Query Neighborhood Hits	212	Target Neighborhood Hits	102	Shared Neighborhood Hits	39
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCTD4_HUMAN
θ value	4.03905 (rank : 163)	NC score	0.241592 (rank : 74)
Query Neighborhood Hits	212	Target Neighborhood Hits	72	Shared Neighborhood Hits	57
SwissProt Accessions	Q8WVF5	Gene names	KCTD4
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD4.

KCTD4_MOUSE
θ value	4.03905 (rank : 164)	NC score	0.242596 (rank : 73)
Query Neighborhood Hits	212	Target Neighborhood Hits	72	Shared Neighborhood Hits	57
SwissProt Accessions	Q9D7X1, Q8CCQ3, Q9CYK4	Gene names	Kctd4
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD4.

KCTD6_HUMAN
θ value	4.03905 (rank : 165)	NC score	0.254778 (rank : 69)
Query Neighborhood Hits	212	Target Neighborhood Hits	70	Shared Neighborhood Hits	56
SwissProt Accessions	Q8NC69, Q8NBS6, Q8TCA6	Gene names	KCTD6
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD6.

KCTD6_MOUSE
θ value	4.03905 (rank : 166)	NC score	0.257073 (rank : 66)
Query Neighborhood Hits	212	Target Neighborhood Hits	70	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BNL5, Q3TXX1	Gene names	Kctd6
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD6.

KCTD9_HUMAN
θ value	4.03905 (rank : 167)	NC score	0.162968 (rank : 112)
Query Neighborhood Hits	212	Target Neighborhood Hits	70	Shared Neighborhood Hits	48
SwissProt Accessions	Q7L273, Q6NUM8, Q9NXV4	Gene names	KCTD9
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD9.

KCTD9_MOUSE
θ value	4.03905 (rank : 168)	NC score	0.167121 (rank : 111)
Query Neighborhood Hits	212	Target Neighborhood Hits	63	Shared Neighborhood Hits	48
SwissProt Accessions	Q80UN1	Gene names	Kctd9
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD9.

MAP4_MOUSE
θ value	4.03905 (rank : 169)	NC score	0.016707 (rank : 156)
Query Neighborhood Hits	212	Target Neighborhood Hits	409	Shared Neighborhood Hits	26
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

SMOO_HUMAN
θ value	4.03905 (rank : 170)	NC score	0.007917 (rank : 175)
Query Neighborhood Hits	212	Target Neighborhood Hits	391	Shared Neighborhood Hits	21
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

ZC3H3_HUMAN
θ value	4.03905 (rank : 171)	NC score	0.007478 (rank : 180)
Query Neighborhood Hits	212	Target Neighborhood Hits	159	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IXZ2, Q14163, Q8N4E2, Q9BUS4	Gene names	ZC3H3, KIAA0150, ZC3HDC3
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

AP3B1_MOUSE
θ value	5.27518 (rank : 172)	NC score	0.002876 (rank : 200)
Query Neighborhood Hits	212	Target Neighborhood Hits	302	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

CC062_HUMAN
θ value	5.27518 (rank : 173)	NC score	0.008780 (rank : 171)
Query Neighborhood Hits	212	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZUJ4, Q6P7E9, Q7Z3X6	Gene names	C3orf62
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf62.

ESCO1_HUMAN
θ value	5.27518 (rank : 174)	NC score	0.006840 (rank : 182)
Query Neighborhood Hits	212	Target Neighborhood Hits	361	Shared Neighborhood Hits	17
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

KCD11_MOUSE
θ value	5.27518 (rank : 175)	NC score	0.109685 (rank : 122)
Query Neighborhood Hits	212	Target Neighborhood Hits	47	Shared Neighborhood Hits	35
SwissProt Accessions	Q8K485	Gene names	Kctd11, Ren
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD11.

KCNK5_HUMAN
θ value	5.27518 (rank : 176)	NC score	0.139156 (rank : 117)
Query Neighborhood Hits	212	Target Neighborhood Hits	102	Shared Neighborhood Hits	73
SwissProt Accessions	O95279	Gene names	KCNK5, TASK2
Domain Architecture
Description	Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2).

LARP4_HUMAN
θ value	5.27518 (rank : 177)	NC score	0.007630 (rank : 179)
Query Neighborhood Hits	212	Target Neighborhood Hits	69	Shared Neighborhood Hits	8
SwissProt Accessions	Q71RC2, Q5CZ97, Q96NF9	Gene names	LARP4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

MINT_HUMAN
θ value	5.27518 (rank : 178)	NC score	0.003519 (rank : 198)
Query Neighborhood Hits	212	Target Neighborhood Hits	1291	Shared Neighborhood Hits	39
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

REXO1_MOUSE
θ value	5.27518 (rank : 179)	NC score	0.005741 (rank : 186)
Query Neighborhood Hits	212	Target Neighborhood Hits	166	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TT28, Q3UMP1, Q69ZR0, Q6NSQ6, Q6PI95, Q9DA29	Gene names	Rexo1, Kiaa1138, Tceb3bp1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1).

SPRL1_MOUSE
θ value	5.27518 (rank : 180)	NC score	0.003919 (rank : 196)
Query Neighborhood Hits	212	Target Neighborhood Hits	403	Shared Neighborhood Hits	14
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

YLPM1_HUMAN
θ value	5.27518 (rank : 181)	NC score	0.010524 (rank : 167)
Query Neighborhood Hits	212	Target Neighborhood Hits	670	Shared Neighborhood Hits	26
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

ABCC9_HUMAN
θ value	6.88961 (rank : 182)	NC score	0.002798 (rank : 201)
Query Neighborhood Hits	212	Target Neighborhood Hits	108	Shared Neighborhood Hits	4
SwissProt Accessions	O60706, O60707	Gene names	ABCC9, SUR2
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 9 (Sulfonylurea receptor 2).

ABCC9_MOUSE
θ value	6.88961 (rank : 183)	NC score	0.002739 (rank : 202)
Query Neighborhood Hits	212	Target Neighborhood Hits	110	Shared Neighborhood Hits	4
SwissProt Accessions	P70170, O08902, O08920, P70171	Gene names	Abcc9, Sur2
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 9 (Sulfonylurea receptor 2).

AN30A_HUMAN
θ value	6.88961 (rank : 184)	NC score	-0.004181 (rank : 219)
Query Neighborhood Hits	212	Target Neighborhood Hits	1119	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

KCNH8_HUMAN
θ value	6.88961 (rank : 185)	NC score	0.038897 (rank : 141)
Query Neighborhood Hits	212	Target Neighborhood Hits	104	Shared Neighborhood Hits	34
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNK3_MOUSE
θ value	6.88961 (rank : 186)	NC score	0.141296 (rank : 114)
Query Neighborhood Hits	212	Target Neighborhood Hits	93	Shared Neighborhood Hits	72
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCTD7_HUMAN
θ value	6.88961 (rank : 187)	NC score	0.197622 (rank : 107)
Query Neighborhood Hits	212	Target Neighborhood Hits	74	Shared Neighborhood Hits	52
SwissProt Accessions	Q96MP8, Q8IVR0	Gene names	KCTD7
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD7.

MDC1_MOUSE
θ value	6.88961 (rank : 188)	NC score	0.012621 (rank : 164)
Query Neighborhood Hits	212	Target Neighborhood Hits	998	Shared Neighborhood Hits	45
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

NOP14_HUMAN
θ value	6.88961 (rank : 189)	NC score	0.001578 (rank : 207)
Query Neighborhood Hits	212	Target Neighborhood Hits	573	Shared Neighborhood Hits	11
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

PLCB3_HUMAN
θ value	6.88961 (rank : 190)	NC score	0.002451 (rank : 205)
Query Neighborhood Hits	212	Target Neighborhood Hits	445	Shared Neighborhood Hits	9
SwissProt Accessions	Q01970	Gene names	PLCB3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

PLCB3_MOUSE
θ value	6.88961 (rank : 191)	NC score	0.002685 (rank : 203)
Query Neighborhood Hits	212	Target Neighborhood Hits	344	Shared Neighborhood Hits	7
SwissProt Accessions	P51432	Gene names	Plcb3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

RBBP6_HUMAN
θ value	6.88961 (rank : 192)	NC score	0.005712 (rank : 187)
Query Neighborhood Hits	212	Target Neighborhood Hits	1135	Shared Neighborhood Hits	41
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RERE_HUMAN
θ value	6.88961 (rank : 193)	NC score	0.004668 (rank : 193)
Query Neighborhood Hits	212	Target Neighborhood Hits	779	Shared Neighborhood Hits	28
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

SGIP1_HUMAN
θ value	6.88961 (rank : 194)	NC score	0.008328 (rank : 173)
Query Neighborhood Hits	212	Target Neighborhood Hits	198	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

ZN628_HUMAN
θ value	6.88961 (rank : 195)	NC score	-0.007145 (rank : 223)
Query Neighborhood Hits	212	Target Neighborhood Hits	814	Shared Neighborhood Hits	7
SwissProt Accessions	Q5EBL2, Q86X34	Gene names	ZNF628
Domain Architecture	No domain graphic available
Description	Zinc finger protein 628.

ZN687_HUMAN
θ value	6.88961 (rank : 196)	NC score	-0.004576 (rank : 220)
Query Neighborhood Hits	212	Target Neighborhood Hits	1244	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

CEND3_MOUSE
θ value	8.99809 (rank : 197)	NC score	-0.000171 (rank : 211)
Query Neighborhood Hits	212	Target Neighborhood Hits	228	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CN092_HUMAN
θ value	8.99809 (rank : 198)	NC score	0.004497 (rank : 195)
Query Neighborhood Hits	212	Target Neighborhood Hits	143	Shared Neighborhood Hits	8
SwissProt Accessions	O94842	Gene names	C14orf92, KIAA0737
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

CN092_MOUSE
θ value	8.99809 (rank : 199)	NC score	0.004651 (rank : 194)
Query Neighborhood Hits	212	Target Neighborhood Hits	206	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

KCD11_HUMAN
θ value	8.99809 (rank : 200)	NC score	0.103796 (rank : 124)
Query Neighborhood Hits	212	Target Neighborhood Hits	50	Shared Neighborhood Hits	37
SwissProt Accessions	Q693B1	Gene names	KCTD11, REN
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD11.

KCNK1_MOUSE
θ value	8.99809 (rank : 201)	NC score	0.049903 (rank : 136)
Query Neighborhood Hits	212	Target Neighborhood Hits	70	Shared Neighborhood Hits	47
SwissProt Accessions	O08581	Gene names	Kcnk1
Domain Architecture
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1).

KCNK9_HUMAN
θ value	8.99809 (rank : 202)	NC score	0.104637 (rank : 123)
Query Neighborhood Hits	212	Target Neighborhood Hits	86	Shared Neighborhood Hits	68
SwissProt Accessions	Q9NPC2, Q2M290, Q540F2	Gene names	KCNK9, TASK3
Domain Architecture
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2).

KCNK9_MOUSE
θ value	8.99809 (rank : 203)	NC score	0.102535 (rank : 125)
Query Neighborhood Hits	212	Target Neighborhood Hits	86	Shared Neighborhood Hits	66
SwissProt Accessions	Q3LS21	Gene names	Kcnk9, Task3
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3).

KCNRG_MOUSE
θ value	8.99809 (rank : 204)	NC score	0.205123 (rank : 102)
Query Neighborhood Hits	212	Target Neighborhood Hits	68	Shared Neighborhood Hits	54
SwissProt Accessions	Q2TUM3, Q6P8J6, Q8C6V1	Gene names	Kcnrg, Clld4
Domain Architecture	No domain graphic available
Description	Putative potassium channel regulatory protein (Potassium channel regulator) (Protein CLLD4).

NARGL_MOUSE
θ value	8.99809 (rank : 205)	NC score	0.002111 (rank : 206)
Query Neighborhood Hits	212	Target Neighborhood Hits	175	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBB4, Q3U7V2	Gene names	Narg1l, Nat2
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated 1-like protein (NARG1-like protein).

PININ_HUMAN
θ value	8.99809 (rank : 206)	NC score	0.007063 (rank : 181)
Query Neighborhood Hits	212	Target Neighborhood Hits	753	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

SAPS1_HUMAN
θ value	8.99809 (rank : 207)	NC score	0.005653 (rank : 188)
Query Neighborhood Hits	212	Target Neighborhood Hits	704	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SENP3_MOUSE
θ value	8.99809 (rank : 208)	NC score	0.003066 (rank : 199)
Query Neighborhood Hits	212	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EP97	Gene names	Senp3, Smt3ip, Smt3ip1
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3) (Smt3-specific isopeptidase 1) (Smt3ip1).

SN1L1_MOUSE
θ value	8.99809 (rank : 209)	NC score	-0.007026 (rank : 222)
Query Neighborhood Hits	212	Target Neighborhood Hits	895	Shared Neighborhood Hits	10
SwissProt Accessions	Q60670	Gene names	Snf1lk, Msk
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1- like kinase).

SYTL2_MOUSE
θ value	8.99809 (rank : 210)	NC score	0.000479 (rank : 209)
Query Neighborhood Hits	212	Target Neighborhood Hits	253	Shared Neighborhood Hits	7
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

TACC2_MOUSE
θ value	8.99809 (rank : 211)	NC score	0.000274 (rank : 210)
Query Neighborhood Hits	212	Target Neighborhood Hits	774	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TGON2_HUMAN
θ value	8.99809 (rank : 212)	NC score	0.007874 (rank : 176)
Query Neighborhood Hits	212	Target Neighborhood Hits	1037	Shared Neighborhood Hits	44
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

KCD12_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.077534 (rank : 131)
Query Neighborhood Hits	212	Target Neighborhood Hits	64	Shared Neighborhood Hits	36
SwissProt Accessions	Q96CX2	Gene names	KCTD12, C13orf2, KIAA1778, PFET1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD12 (Pfetin) (Predominantly fetal expressed T1 domain).

KCD12_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.072887 (rank : 132)
Query Neighborhood Hits	212	Target Neighborhood Hits	66	Shared Neighborhood Hits	38
SwissProt Accessions	Q6WVG3	Gene names	Kctd12, Pfet1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD12 (Pfetin) (Predominantly fetal expressed T1 domain).

KCD16_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.078909 (rank : 130)
Query Neighborhood Hits	212	Target Neighborhood Hits	60	Shared Neighborhood Hits	39
SwissProt Accessions	Q68DU8, Q9P2M9	Gene names	KCTD16, KIAA1317
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD16.

KCD16_MOUSE
θ value	θ > 10 (rank : 216)	NC score	0.083160 (rank : 129)
Query Neighborhood Hits	212	Target Neighborhood Hits	58	Shared Neighborhood Hits	40
SwissProt Accessions	Q5DTY9, Q78Y50	Gene names	Kctd16, Kiaa1317
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD16.

KCNK3_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.138464 (rank : 118)
Query Neighborhood Hits	212	Target Neighborhood Hits	88	Shared Neighborhood Hits	69
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK4_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.065685 (rank : 135)
Query Neighborhood Hits	212	Target Neighborhood Hits	109	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCNK6_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.122470 (rank : 121)
Query Neighborhood Hits	212	Target Neighborhood Hits	79	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KCNK7_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.067317 (rank : 134)
Query Neighborhood Hits	212	Target Neighborhood Hits	42	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y2U2, Q9Y2U3, Q9Y2U4	Gene names	KCNK7
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7.

KCNK7_MOUSE
θ value	θ > 10 (rank : 221)	NC score	0.071615 (rank : 133)
Query Neighborhood Hits	212	Target Neighborhood Hits	53	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z2T1, Q9QXY0, Q9QYE8, Q9R1V1, Q9R242	Gene names	Kcnk7, Dpkch3, Kcnk6, Kcnk8, Knot1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7 (Putative potassium channel DP3) (Double-pore K(+) channel 3) (Neuromuscular two p domain potassium channel).

KCTD8_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.088770 (rank : 127)
Query Neighborhood Hits	212	Target Neighborhood Hits	91	Shared Neighborhood Hits	38
SwissProt Accessions	Q6ZWB6	Gene names	KCTD8
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD8.

KCTD8_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.098483 (rank : 126)
Query Neighborhood Hits	212	Target Neighborhood Hits	97	Shared Neighborhood Hits	42
SwissProt Accessions	Q50H33, Q8BR74, Q8C4C2, Q8C906, Q8C9B0, Q8CAA9	Gene names	Kctd8
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD8.

Hits sorted by NC score

KCNB2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	212	Target Neighborhood Hits	212	Shared Neighborhood Hits	212
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNB1_MOUSE
NC score	0.992897 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	212	Target Neighborhood Hits	154	Shared Neighborhood Hits	131
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNB1_HUMAN
NC score	0.992590 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	212	Target Neighborhood Hits	169	Shared Neighborhood Hits	130
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNF1_HUMAN
NC score	0.979702 (rank : 4)	θ value	4.06505e-93 (rank : 8)
Query Neighborhood Hits	212	Target Neighborhood Hits	109	Shared Neighborhood Hits	103
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCNV2_HUMAN
NC score	0.979574 (rank : 5)	θ value	1.70789e-91 (rank : 9)
Query Neighborhood Hits	212	Target Neighborhood Hits	137	Shared Neighborhood Hits	118
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCNS2_MOUSE
NC score	0.979406 (rank : 6)	θ value	1.94503e-103 (rank : 5)
Query Neighborhood Hits	212	Target Neighborhood Hits	130	Shared Neighborhood Hits	123
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_HUMAN
NC score	0.979376 (rank : 7)	θ value	4.6295e-105 (rank : 4)
Query Neighborhood Hits	212	Target Neighborhood Hits	129	Shared Neighborhood Hits	123
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS3_HUMAN
NC score	0.977532 (rank : 8)	θ value	1.3939e-101 (rank : 6)
Query Neighborhood Hits	212	Target Neighborhood Hits	125	Shared Neighborhood Hits	111
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

KCNS1_HUMAN
NC score	0.975929 (rank : 9)	θ value	7.91507e-97 (rank : 7)
Query Neighborhood Hits	212	Target Neighborhood Hits	116	Shared Neighborhood Hits	109
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNS1_MOUSE
NC score	0.972482 (rank : 10)	θ value	2.5521e-87 (rank : 12)
Query Neighborhood Hits	212	Target Neighborhood Hits	114	Shared Neighborhood Hits	104
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNG1_HUMAN
NC score	0.968667 (rank : 11)	θ value	1.88829e-90 (rank : 10)
Query Neighborhood Hits	212	Target Neighborhood Hits	103	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNG3_MOUSE
NC score	0.966239 (rank : 12)	θ value	3.12697e-77 (rank : 14)
Query Neighborhood Hits	212	Target Neighborhood Hits	91	Shared Neighborhood Hits	90
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNG3_HUMAN
NC score	0.965805 (rank : 13)	θ value	5.33382e-77 (rank : 15)
Query Neighborhood Hits	212	Target Neighborhood Hits	91	Shared Neighborhood Hits	88
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNG4_HUMAN
NC score	0.964436 (rank : 14)	θ value	2.30828e-88 (rank : 11)
Query Neighborhood Hits	212	Target Neighborhood Hits	99	Shared Neighborhood Hits	90
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNG2_HUMAN
NC score	0.963261 (rank : 15)	θ value	2.47191e-82 (rank : 13)
Query Neighborhood Hits	212	Target Neighborhood Hits	83	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNC1_HUMAN
NC score	0.953494 (rank : 16)	θ value	5.51964e-74 (rank : 16)
Query Neighborhood Hits	212	Target Neighborhood Hits	133	Shared Neighborhood Hits	119
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC1_MOUSE
NC score	0.953313 (rank : 17)	θ value	7.20884e-74 (rank : 17)
Query Neighborhood Hits	212	Target Neighborhood Hits	133	Shared Neighborhood Hits	119
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC4_HUMAN
NC score	0.949214 (rank : 18)	θ value	1.7756e-72 (rank : 18)
Query Neighborhood Hits	212	Target Neighborhood Hits	141	Shared Neighborhood Hits	116
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KCNC4_MOUSE
NC score	0.948678 (rank : 19)	θ value	2.56397e-71 (rank : 19)
Query Neighborhood Hits	212	Target Neighborhood Hits	130	Shared Neighborhood Hits	115
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCND2_HUMAN
NC score	0.943083 (rank : 20)	θ value	7.71989e-68 (rank : 21)
Query Neighborhood Hits	212	Target Neighborhood Hits	154	Shared Neighborhood Hits	130
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_MOUSE
NC score	0.943077 (rank : 21)	θ value	5.91091e-68 (rank : 20)
Query Neighborhood Hits	212	Target Neighborhood Hits	156	Shared Neighborhood Hits	130
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND3_MOUSE
NC score	0.941964 (rank : 22)	θ value	1.2325e-65 (rank : 25)
Query Neighborhood Hits	212	Target Neighborhood Hits	162	Shared Neighborhood Hits	130
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_HUMAN
NC score	0.941515 (rank : 23)	θ value	1.2325e-65 (rank : 24)
Query Neighborhood Hits	212	Target Neighborhood Hits	162	Shared Neighborhood Hits	130
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND1_HUMAN
NC score	0.940931 (rank : 24)	θ value	2.32439e-64 (rank : 29)
Query Neighborhood Hits	212	Target Neighborhood Hits	160	Shared Neighborhood Hits	128
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCND1_MOUSE
NC score	0.940390 (rank : 25)	θ value	1.04338e-64 (rank : 26)
Query Neighborhood Hits	212	Target Neighborhood Hits	165	Shared Neighborhood Hits	129
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCNA1_MOUSE
NC score	0.937655 (rank : 26)	θ value	6.53529e-67 (rank : 22)
Query Neighborhood Hits	212	Target Neighborhood Hits	103	Shared Neighborhood Hits	95
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNA1_HUMAN
NC score	0.937309 (rank : 27)	θ value	8.53533e-67 (rank : 23)
Query Neighborhood Hits	212	Target Neighborhood Hits	104	Shared Neighborhood Hits	94
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNA3_HUMAN
NC score	0.934477 (rank : 28)	θ value	4.38363e-63 (rank : 31)
Query Neighborhood Hits	212	Target Neighborhood Hits	101	Shared Neighborhood Hits	90
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNA2_MOUSE
NC score	0.934298 (rank : 29)	θ value	2.32439e-64 (rank : 28)
Query Neighborhood Hits	212	Target Neighborhood Hits	102	Shared Neighborhood Hits	93
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNA2_HUMAN
NC score	0.934078 (rank : 30)	θ value	1.77973e-64 (rank : 27)
Query Neighborhood Hits	212	Target Neighborhood Hits	101	Shared Neighborhood Hits	92
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNA6_MOUSE
NC score	0.933977 (rank : 31)	θ value	1.15626e-55 (rank : 37)
Query Neighborhood Hits	212	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNA3_MOUSE
NC score	0.933903 (rank : 32)	θ value	7.47731e-63 (rank : 32)
Query Neighborhood Hits	212	Target Neighborhood Hits	103	Shared Neighborhood Hits	90
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCNA6_HUMAN
NC score	0.933568 (rank : 33)	θ value	2.7521e-57 (rank : 35)
Query Neighborhood Hits	212	Target Neighborhood Hits	100	Shared Neighborhood Hits	92
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNA4_MOUSE
NC score	0.932878 (rank : 34)	θ value	2.84138e-62 (rank : 33)
Query Neighborhood Hits	212	Target Neighborhood Hits	98	Shared Neighborhood Hits	85
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNA4_HUMAN
NC score	0.932792 (rank : 35)	θ value	1.15359e-63 (rank : 30)
Query Neighborhood Hits	212	Target Neighborhood Hits	108	Shared Neighborhood Hits	89
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNC3_MOUSE
NC score	0.932190 (rank : 36)	θ value	9.48078e-50 (rank : 38)
Query Neighborhood Hits	212	Target Neighborhood Hits	173	Shared Neighborhood Hits	113
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNA5_MOUSE
NC score	0.931696 (rank : 37)	θ value	4.69435e-57 (rank : 36)
Query Neighborhood Hits	212	Target Neighborhood Hits	119	Shared Neighborhood Hits	93
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCNA5_HUMAN
NC score	0.931258 (rank : 38)	θ value	4.24587e-58 (rank : 34)
Query Neighborhood Hits	212	Target Neighborhood Hits	124	Shared Neighborhood Hits	89
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNC3_HUMAN
NC score	0.930194 (rank : 39)	θ value	3.60269e-49 (rank : 39)
Query Neighborhood Hits	212	Target Neighborhood Hits	256	Shared Neighborhood Hits	121
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNQ1_HUMAN
NC score	0.751155 (rank : 40)	θ value	2.13179e-17 (rank : 42)
Query Neighborhood Hits	212	Target Neighborhood Hits	99	Shared Neighborhood Hits	77
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ1_MOUSE
NC score	0.744456 (rank : 41)	θ value	8.10077e-17 (rank : 43)
Query Neighborhood Hits	212	Target Neighborhood Hits	175	Shared Neighborhood Hits	81
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ2_HUMAN
NC score	0.721634 (rank : 42)	θ value	1.058e-16 (rank : 44)
Query Neighborhood Hits	212	Target Neighborhood Hits	114	Shared Neighborhood Hits	77
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ2_MOUSE
NC score	0.719692 (rank : 43)	θ value	5.25075e-16 (rank : 45)
Query Neighborhood Hits	212	Target Neighborhood Hits	163	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ5_HUMAN
NC score	0.713352 (rank : 44)	θ value	4.29542e-18 (rank : 40)
Query Neighborhood Hits	212	Target Neighborhood Hits	163	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

KCNQ4_HUMAN
NC score	0.712824 (rank : 45)	θ value	1.24977e-17 (rank : 41)
Query Neighborhood Hits	212	Target Neighborhood Hits	136	Shared Neighborhood Hits	87
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCNQ3_MOUSE
NC score	0.681673 (rank : 46)	θ value	6.41864e-14 (rank : 47)
Query Neighborhood Hits	212	Target Neighborhood Hits	105	Shared Neighborhood Hits	78
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_HUMAN
NC score	0.680859 (rank : 47)	θ value	6.41864e-14 (rank : 46)
Query Neighborhood Hits	212	Target Neighborhood Hits	114	Shared Neighborhood Hits	79
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCMA1_MOUSE
NC score	0.493651 (rank : 48)	θ value	1.63604e-09 (rank : 49)
Query Neighborhood Hits	212	Target Neighborhood Hits	94	Shared Neighborhood Hits	73
SwissProt Accessions	Q08460, Q64703, Q8VHF1, Q9R196	Gene names	Kcnma1, Kcnma
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (mSlo) (mSlo1).

KCMA1_HUMAN
NC score	0.492745 (rank : 49)	θ value	1.63604e-09 (rank : 48)
Query Neighborhood Hits	212	Target Neighborhood Hits	96	Shared Neighborhood Hits	73
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

KCNN4_MOUSE
NC score	0.354904 (rank : 50)	θ value	0.00020696 (rank : 64)
Query Neighborhood Hits	212	Target Neighborhood Hits	85	Shared Neighborhood Hits	68
SwissProt Accessions	O89109, Q3U1J8, Q9CY39	Gene names	Kcnn4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1).

KCNN4_HUMAN
NC score	0.353230 (rank : 51)	θ value	0.00020696 (rank : 63)
Query Neighborhood Hits	212	Target Neighborhood Hits	90	Shared Neighborhood Hits	68
SwissProt Accessions	O15554	Gene names	KCNN4, IK1, IKCA1, KCA4, SK4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1) (IKCa1) (Putative Gardos channel).

KCTD1_HUMAN
NC score	0.296232 (rank : 52)	θ value	0.00228821 (rank : 72)
Query Neighborhood Hits	212	Target Neighborhood Hits	74	Shared Neighborhood Hits	61
SwissProt Accessions	Q719H9	Gene names	KCTD1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD1.

KCTD1_MOUSE
NC score	0.296232 (rank : 53)	θ value	0.00228821 (rank : 73)
Query Neighborhood Hits	212	Target Neighborhood Hits	74	Shared Neighborhood Hits	61
SwissProt Accessions	Q5M956, Q5EER9	Gene names	Kctd1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD1.

KCNN2_HUMAN
NC score	0.288071 (rank : 54)	θ value	0.00665767 (rank : 80)
Query Neighborhood Hits	212	Target Neighborhood Hits	117	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H2S1	Gene names	KCNN2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KCNN2_MOUSE
NC score	0.288058 (rank : 55)	θ value	0.00665767 (rank : 81)
Query Neighborhood Hits	212	Target Neighborhood Hits	120	Shared Neighborhood Hits	67
SwissProt Accessions	P58390	Gene names	Kcnn2, Sk2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KCTD2_HUMAN
NC score	0.285910 (rank : 56)	θ value	0.000786445 (rank : 68)
Query Neighborhood Hits	212	Target Neighborhood Hits	69	Shared Neighborhood Hits	50
SwissProt Accessions	Q14681	Gene names	KCTD2, KIAA0176
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD2.

KCNN3_HUMAN
NC score	0.282993 (rank : 57)	θ value	0.00869519 (rank : 82)
Query Neighborhood Hits	212	Target Neighborhood Hits	216	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UGI6, O43517	Gene names	KCNN3, K3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3) (SKCa3).

KCNN3_MOUSE
NC score	0.281574 (rank : 58)	θ value	0.00869519 (rank : 83)
Query Neighborhood Hits	212	Target Neighborhood Hits	171	Shared Neighborhood Hits	71
SwissProt Accessions	P58391	Gene names	Kcnn3, Sk3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3).

KCNN1_MOUSE
NC score	0.280444 (rank : 59)	θ value	0.00390308 (rank : 77)
Query Neighborhood Hits	212	Target Neighborhood Hits	117	Shared Neighborhood Hits	69
SwissProt Accessions	Q9EQR3, Q99JA9	Gene names	Kcnn1, Sk1
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 1 (SK1).

KCNN1_HUMAN
NC score	0.279277 (rank : 60)	θ value	0.00390308 (rank : 76)
Query Neighborhood Hits	212	Target Neighborhood Hits	125	Shared Neighborhood Hits	67
SwissProt Accessions	Q92952	Gene names	KCNN1, SK
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 1 (SK1).

KCD15_HUMAN
NC score	0.277791 (rank : 61)	θ value	0.21417 (rank : 105)
Query Neighborhood Hits	212	Target Neighborhood Hits	76	Shared Neighborhood Hits	61
SwissProt Accessions	Q96SI1, Q9BVI6	Gene names	KCTD15
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD15.

KCTD5_MOUSE
NC score	0.265661 (rank : 62)	θ value	0.00509761 (rank : 79)
Query Neighborhood Hits	212	Target Neighborhood Hits	64	Shared Neighborhood Hits	50
SwissProt Accessions	Q8VC57	Gene names	Kctd5
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD5.

KCD15_MOUSE
NC score	0.265542 (rank : 63)	θ value	1.06291 (rank : 126)
Query Neighborhood Hits	212	Target Neighborhood Hits	78	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K0E1	Gene names	Kctd15
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD15.

SC11A_HUMAN
NC score	0.265451 (rank : 64)	θ value	4.1701e-05 (rank : 59)
Query Neighborhood Hits	212	Target Neighborhood Hits	111	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

KCTD5_HUMAN
NC score	0.264366 (rank : 65)	θ value	0.00390308 (rank : 78)
Query Neighborhood Hits	212	Target Neighborhood Hits	66	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NXV2	Gene names	KCTD5
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD5.

KCTD6_MOUSE
NC score	0.257073 (rank : 66)	θ value	4.03905 (rank : 166)
Query Neighborhood Hits	212	Target Neighborhood Hits	70	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BNL5, Q3TXX1	Gene names	Kctd6
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD6.

CAC1H_MOUSE
NC score	0.256258 (rank : 67)	θ value	1.43324e-05 (rank : 57)
Query Neighborhood Hits	212	Target Neighborhood Hits	230	Shared Neighborhood Hits	69
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CAC1I_HUMAN
NC score	0.255048 (rank : 68)	θ value	4.92598e-06 (rank : 54)
Query Neighborhood Hits	212	Target Neighborhood Hits	138	Shared Neighborhood Hits	64
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

KCTD6_HUMAN
NC score	0.254778 (rank : 69)	θ value	4.03905 (rank : 165)
Query Neighborhood Hits	212	Target Neighborhood Hits	70	Shared Neighborhood Hits	56
SwissProt Accessions	Q8NC69, Q8NBS6, Q8TCA6	Gene names	KCTD6
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD6.

CAC1H_HUMAN
NC score	0.252145 (rank : 70)	θ value	1.09739e-05 (rank : 55)
Query Neighborhood Hits	212	Target Neighborhood Hits	307	Shared Neighborhood Hits	67
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

SCN4A_HUMAN
NC score	0.248805 (rank : 71)	θ value	5.44631e-05 (rank : 60)
Query Neighborhood Hits	212	Target Neighborhood Hits	133	Shared Neighborhood Hits	71
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

SC11A_MOUSE
NC score	0.248746 (rank : 72)	θ value	0.00228821 (rank : 74)
Query Neighborhood Hits	212	Target Neighborhood Hits	116	Shared Neighborhood Hits	67
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

KCTD4_MOUSE
NC score	0.242596 (rank : 73)	θ value	4.03905 (rank : 164)
Query Neighborhood Hits	212	Target Neighborhood Hits	72	Shared Neighborhood Hits	57
SwissProt Accessions	Q9D7X1, Q8CCQ3, Q9CYK4	Gene names	Kctd4
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD4.

KCTD4_HUMAN
NC score	0.241592 (rank : 74)	θ value	4.03905 (rank : 163)
Query Neighborhood Hits	212	Target Neighborhood Hits	72	Shared Neighborhood Hits	57
SwissProt Accessions	Q8WVF5	Gene names	KCTD4
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD4.

KCTD3_HUMAN
NC score	0.233280 (rank : 75)	θ value	1.06291 (rank : 129)
Query Neighborhood Hits	212	Target Neighborhood Hits	90	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y597, Q49AG7, Q504Q9, Q6PJN6, Q8ND58, Q8NDJ0, Q8WX16	Gene names	KCTD3
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD3 (NY-REN-45 antigen).

KCNT1_HUMAN
NC score	0.229336 (rank : 76)	θ value	0.0252991 (rank : 92)
Query Neighborhood Hits	212	Target Neighborhood Hits	87	Shared Neighborhood Hits	66
SwissProt Accessions	Q5JUK3, Q9P2C5	Gene names	KCNT1, KIAA1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1 (KCa4.1).

CAC1D_HUMAN
NC score	0.225777 (rank : 77)	θ value	4.92598e-06 (rank : 53)
Query Neighborhood Hits	212	Target Neighborhood Hits	118	Shared Neighborhood Hits	61
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CAC1G_HUMAN
NC score	0.224058 (rank : 78)	θ value	0.00134147 (rank : 71)
Query Neighborhood Hits	212	Target Neighborhood Hits	587	Shared Neighborhood Hits	76
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

SC10A_MOUSE
NC score	0.222576 (rank : 79)	θ value	0.000158464 (rank : 62)
Query Neighborhood Hits	212	Target Neighborhood Hits	107	Shared Neighborhood Hits	58
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

KCNRG_HUMAN
NC score	0.222349 (rank : 80)	θ value	0.47712 (rank : 112)
Query Neighborhood Hits	212	Target Neighborhood Hits	68	Shared Neighborhood Hits	54
SwissProt Accessions	Q8N5I3, Q8IU75, Q8N3Q9	Gene names	KCNRG, CLLD4
Domain Architecture	No domain graphic available
Description	Putative potassium channel regulatory protein (Potassium channel regulator) (Protein CLLD4).

KCTD7_MOUSE
NC score	0.222028 (rank : 81)	θ value	1.38821 (rank : 135)
Query Neighborhood Hits	212	Target Neighborhood Hits	69	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BJK1, Q3USA6, Q8C0S7	Gene names	Kctd7
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD7.

CAC1F_MOUSE
NC score	0.220991 (rank : 82)	θ value	0.0148317 (rank : 88)
Query Neighborhood Hits	212	Target Neighborhood Hits	142	Shared Neighborhood Hits	61
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

KCTD3_MOUSE
NC score	0.220332 (rank : 83)	θ value	1.06291 (rank : 130)
Query Neighborhood Hits	212	Target Neighborhood Hits	85	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BFX3, Q6P7X4	Gene names	Kctd3
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD3.

CAC1F_HUMAN
NC score	0.220106 (rank : 84)	θ value	0.0148317 (rank : 87)
Query Neighborhood Hits	212	Target Neighborhood Hits	141	Shared Neighborhood Hits	61
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1B_MOUSE
NC score	0.218013 (rank : 85)	θ value	0.0148317 (rank : 86)
Query Neighborhood Hits	212	Target Neighborhood Hits	351	Shared Neighborhood Hits	71
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

SCN3A_HUMAN
NC score	0.217044 (rank : 86)	θ value	3.41135e-07 (rank : 50)
Query Neighborhood Hits	212	Target Neighborhood Hits	115	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

CAC1C_MOUSE
NC score	0.216935 (rank : 87)	θ value	4.45536e-07 (rank : 51)
Query Neighborhood Hits	212	Target Neighborhood Hits	130	Shared Neighborhood Hits	59
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CAC1A_MOUSE
NC score	0.216754 (rank : 88)	θ value	0.0193708 (rank : 90)
Query Neighborhood Hits	212	Target Neighborhood Hits	267	Shared Neighborhood Hits	73
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1A_HUMAN
NC score	0.216692 (rank : 89)	θ value	0.0193708 (rank : 89)
Query Neighborhood Hits	212	Target Neighborhood Hits	387	Shared Neighborhood Hits	75
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

SCN9A_HUMAN
NC score	0.216165 (rank : 90)	θ value	9.29e-05 (rank : 61)
Query Neighborhood Hits	212	Target Neighborhood Hits	157	Shared Neighborhood Hits	57
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

SCN5A_HUMAN
NC score	0.215547 (rank : 91)	θ value	0.00102713 (rank : 70)
Query Neighborhood Hits	212	Target Neighborhood Hits	145	Shared Neighborhood Hits	56
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

CAC1S_HUMAN
NC score	0.214094 (rank : 92)	θ value	4.1701e-05 (rank : 58)
Query Neighborhood Hits	212	Target Neighborhood Hits	92	Shared Neighborhood Hits	55
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

SCN8A_MOUSE
NC score	0.213705 (rank : 93)	θ value	0.000270298 (rank : 66)
Query Neighborhood Hits	212	Target Neighborhood Hits	136	Shared Neighborhood Hits	57
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

KCD17_HUMAN
NC score	0.213570 (rank : 94)	θ value	0.0736092 (rank : 99)
Query Neighborhood Hits	212	Target Neighborhood Hits	85	Shared Neighborhood Hits	47
SwissProt Accessions	Q8N5Z5, O95517	Gene names	KCTD17
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD17.

SCN8A_HUMAN
NC score	0.213500 (rank : 95)	θ value	0.000270298 (rank : 65)
Query Neighborhood Hits	212	Target Neighborhood Hits	135	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

CAC1B_HUMAN
NC score	0.210969 (rank : 96)	θ value	0.0431538 (rank : 94)
Query Neighborhood Hits	212	Target Neighborhood Hits	257	Shared Neighborhood Hits	60
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

SC10A_HUMAN
NC score	0.210427 (rank : 97)	θ value	0.000461057 (rank : 67)
Query Neighborhood Hits	212	Target Neighborhood Hits	116	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

SCN1A_HUMAN
NC score	0.209533 (rank : 98)	θ value	1.09739e-05 (rank : 56)
Query Neighborhood Hits	212	Target Neighborhood Hits	148	Shared Neighborhood Hits	54
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

CAC1S_MOUSE
NC score	0.209465 (rank : 99)	θ value	0.00298849 (rank : 75)
Query Neighborhood Hits	212	Target Neighborhood Hits	98	Shared Neighborhood Hits	58
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

SCN2A_HUMAN
NC score	0.208000 (rank : 100)	θ value	1.69304e-06 (rank : 52)
Query Neighborhood Hits	212	Target Neighborhood Hits	157	Shared Neighborhood Hits	54
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

CAC1C_HUMAN
NC score	0.206996 (rank : 101)	θ value	0.00102713 (rank : 69)
Query Neighborhood Hits	212	Target Neighborhood Hits	158	Shared Neighborhood Hits	59
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

KCNRG_MOUSE
NC score	0.205123 (rank : 102)	θ value	8.99809 (rank : 204)
Query Neighborhood Hits	212	Target Neighborhood Hits	68	Shared Neighborhood Hits	54
SwissProt Accessions	Q2TUM3, Q6P8J6, Q8C6V1	Gene names	Kcnrg, Clld4
Domain Architecture	No domain graphic available
Description	Putative potassium channel regulatory protein (Potassium channel regulator) (Protein CLLD4).

KCNKA_HUMAN
NC score	0.204138 (rank : 103)	θ value	0.279714 (rank : 109)
Query Neighborhood Hits	212	Target Neighborhood Hits	111	Shared Neighborhood Hits	77
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

CAC1E_MOUSE
NC score	0.203732 (rank : 104)	θ value	0.0736092 (rank : 98)
Query Neighborhood Hits	212	Target Neighborhood Hits	167	Shared Neighborhood Hits	56
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_HUMAN
NC score	0.203431 (rank : 105)	θ value	0.0736092 (rank : 97)
Query Neighborhood Hits	212	Target Neighborhood Hits	148	Shared Neighborhood Hits	58
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

SCN7A_HUMAN
NC score	0.197786 (rank : 106)	θ value	0.0563607 (rank : 96)
Query Neighborhood Hits	212	Target Neighborhood Hits	135	Shared Neighborhood Hits	62
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

KCTD7_HUMAN
NC score	0.197622 (rank : 107)	θ value	6.88961 (rank : 187)
Query Neighborhood Hits	212	Target Neighborhood Hits	74	Shared Neighborhood Hits	52
SwissProt Accessions	Q96MP8, Q8IVR0	Gene names	KCTD7
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD7.

KCD14_HUMAN
NC score	0.179949 (rank : 108)	θ value	0.21417 (rank : 104)
Query Neighborhood Hits	212	Target Neighborhood Hits	59	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BQ13	Gene names	KCTD14
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD14.

KCNKH_HUMAN
NC score	0.177716 (rank : 109)	θ value	0.365318 (rank : 110)
Query Neighborhood Hits	212	Target Neighborhood Hits	89	Shared Neighborhood Hits	70
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

KCNKF_HUMAN
NC score	0.167410 (rank : 110)	θ value	1.81305 (rank : 142)
Query Neighborhood Hits	212	Target Neighborhood Hits	87	Shared Neighborhood Hits	69
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

KCTD9_MOUSE
NC score	0.167121 (rank : 111)	θ value	4.03905 (rank : 168)
Query Neighborhood Hits	212	Target Neighborhood Hits	63	Shared Neighborhood Hits	48
SwissProt Accessions	Q80UN1	Gene names	Kctd9
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD9.

KCTD9_HUMAN
NC score	0.162968 (rank : 112)	θ value	4.03905 (rank : 167)
Query Neighborhood Hits	212	Target Neighborhood Hits	70	Shared Neighborhood Hits	48
SwissProt Accessions	Q7L273, Q6NUM8, Q9NXV4	Gene names	KCTD9
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD9.

KCNKG_HUMAN
NC score	0.151484 (rank : 113)	θ value	3.0926 (rank : 152)
Query Neighborhood Hits	212	Target Neighborhood Hits	90	Shared Neighborhood Hits	73
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

KCNK3_MOUSE
NC score	0.141296 (rank : 114)	θ value	6.88961 (rank : 186)
Query Neighborhood Hits	212	Target Neighborhood Hits	93	Shared Neighborhood Hits	72
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNT1_MOUSE
NC score	0.140791 (rank : 115)	θ value	2.36792 (rank : 146)
Query Neighborhood Hits	212	Target Neighborhood Hits	69	Shared Neighborhood Hits	52
SwissProt Accessions	Q6ZPR4, Q8C3E7	Gene names	Kcnt1, Kiaa1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1.

KCTD2_MOUSE
NC score	0.139729 (rank : 116)	θ value	1.38821 (rank : 134)
Query Neighborhood Hits	212	Target Neighborhood Hits	55	Shared Neighborhood Hits	42
SwissProt Accessions	Q8CEZ0	Gene names	Kctd2
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD2.

KCNK5_HUMAN
NC score	0.139156 (rank : 117)	θ value	5.27518 (rank : 176)
Query Neighborhood Hits	212	Target Neighborhood Hits	102	Shared Neighborhood Hits	73
SwissProt Accessions	O95279	Gene names	KCNK5, TASK2
Domain Architecture
Description	Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2).

KCNK3_HUMAN
NC score	0.138464 (rank : 118)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	212	Target Neighborhood Hits	88	Shared Neighborhood Hits	69
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK2_MOUSE
NC score	0.133867 (rank : 119)	θ value	1.06291 (rank : 128)
Query Neighborhood Hits	212	Target Neighborhood Hits	88	Shared Neighborhood Hits	67
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNK2_HUMAN
NC score	0.130662 (rank : 120)	θ value	1.06291 (rank : 127)
Query Neighborhood Hits	212	Target Neighborhood Hits	86	Shared Neighborhood Hits	66
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNK6_HUMAN
NC score	0.122470 (rank : 121)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	212	Target Neighborhood Hits	79	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KCD11_MOUSE
NC score	0.109685 (rank : 122)	θ value	5.27518 (rank : 175)
Query Neighborhood Hits	212	Target Neighborhood Hits	47	Shared Neighborhood Hits	35
SwissProt Accessions	Q8K485	Gene names	Kctd11, Ren
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD11.

KCNK9_HUMAN
NC score	0.104637 (rank : 123)	θ value	8.99809 (rank : 202)
Query Neighborhood Hits	212	Target Neighborhood Hits	86	Shared Neighborhood Hits	68
SwissProt Accessions	Q9NPC2, Q2M290, Q540F2	Gene names	KCNK9, TASK3
Domain Architecture
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2).

KCD11_HUMAN
NC score	0.103796 (rank : 124)	θ value	8.99809 (rank : 200)
Query Neighborhood Hits	212	Target Neighborhood Hits	50	Shared Neighborhood Hits	37
SwissProt Accessions	Q693B1	Gene names	KCTD11, REN
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD11.

KCNK9_MOUSE
NC score	0.102535 (rank : 125)	θ value	8.99809 (rank : 203)
Query Neighborhood Hits	212	Target Neighborhood Hits	86	Shared Neighborhood Hits	66
SwissProt Accessions	Q3LS21	Gene names	Kcnk9, Task3
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3).

KCTD8_MOUSE
NC score	0.098483 (rank : 126)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	212	Target Neighborhood Hits	97	Shared Neighborhood Hits	42
SwissProt Accessions	Q50H33, Q8BR74, Q8C4C2, Q8C906, Q8C9B0, Q8CAA9	Gene names	Kctd8
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD8.

KCTD8_HUMAN
NC score	0.088770 (rank : 127)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	212	Target Neighborhood Hits	91	Shared Neighborhood Hits	38
SwissProt Accessions	Q6ZWB6	Gene names	KCTD8
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD8.

KCNK4_MOUSE
NC score	0.087966 (rank : 128)	θ value	0.813845 (rank : 119)
Query Neighborhood Hits	212	Target Neighborhood Hits	118	Shared Neighborhood Hits	55
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

KCD16_MOUSE
NC score	0.083160 (rank : 129)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	212	Target Neighborhood Hits	58	Shared Neighborhood Hits	40
SwissProt Accessions	Q5DTY9, Q78Y50	Gene names	Kctd16, Kiaa1317
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD16.

KCD16_HUMAN
NC score	0.078909 (rank : 130)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	212	Target Neighborhood Hits	60	Shared Neighborhood Hits	39
SwissProt Accessions	Q68DU8, Q9P2M9	Gene names	KCTD16, KIAA1317
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD16.

KCD12_HUMAN
NC score	0.077534 (rank : 131)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	212	Target Neighborhood Hits	64	Shared Neighborhood Hits	36
SwissProt Accessions	Q96CX2	Gene names	KCTD12, C13orf2, KIAA1778, PFET1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD12 (Pfetin) (Predominantly fetal expressed T1 domain).

KCD12_MOUSE
NC score	0.072887 (rank : 132)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	212	Target Neighborhood Hits	66	Shared Neighborhood Hits	38
SwissProt Accessions	Q6WVG3	Gene names	Kctd12, Pfet1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD12 (Pfetin) (Predominantly fetal expressed T1 domain).

KCNK7_MOUSE
NC score	0.071615 (rank : 133)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	212	Target Neighborhood Hits	53	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z2T1, Q9QXY0, Q9QYE8, Q9R1V1, Q9R242	Gene names	Kcnk7, Dpkch3, Kcnk6, Kcnk8, Knot1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7 (Putative potassium channel DP3) (Double-pore K(+) channel 3) (Neuromuscular two p domain potassium channel).

KCNK7_HUMAN
NC score	0.067317 (rank : 134)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	212	Target Neighborhood Hits	42	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y2U2, Q9Y2U3, Q9Y2U4	Gene names	KCNK7
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7.

KCNK4_HUMAN
NC score	0.065685 (rank : 135)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	212	Target Neighborhood Hits	109	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCNK1_MOUSE
NC score	0.049903 (rank : 136)	θ value	8.99809 (rank : 201)
Query Neighborhood Hits	212	Target Neighborhood Hits	70	Shared Neighborhood Hits	47
SwissProt Accessions	O08581	Gene names	Kcnk1
Domain Architecture
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1).

KCNH5_MOUSE
NC score	0.043672 (rank : 137)	θ value	4.03905 (rank : 162)
Query Neighborhood Hits	212	Target Neighborhood Hits	102	Shared Neighborhood Hits	39
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH5_HUMAN
NC score	0.043655 (rank : 138)	θ value	4.03905 (rank : 161)
Query Neighborhood Hits	212	Target Neighborhood Hits	99	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH1_MOUSE
NC score	0.043103 (rank : 139)	θ value	3.0926 (rank : 151)
Query Neighborhood Hits	212	Target Neighborhood Hits	94	Shared Neighborhood Hits	37
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNH1_HUMAN
NC score	0.043072 (rank : 140)	θ value	3.0926 (rank : 150)
Query Neighborhood Hits	212	Target Neighborhood Hits	98	Shared Neighborhood Hits	37
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH8_HUMAN
NC score	0.038897 (rank : 141)	θ value	6.88961 (rank : 185)
Query Neighborhood Hits	212	Target Neighborhood Hits	104	Shared Neighborhood Hits	34
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH6_HUMAN
NC score	0.031826 (rank : 142)	θ value	0.813845 (rank : 118)
Query Neighborhood Hits	212	Target Neighborhood Hits	222	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

BTBDC_HUMAN
NC score	0.025913 (rank : 143)	θ value	0.279714 (rank : 107)
Query Neighborhood Hits	212	Target Neighborhood Hits	248	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

VGF_HUMAN
NC score	0.025036 (rank : 144)	θ value	0.62314 (rank : 116)
Query Neighborhood Hits	212	Target Neighborhood Hits	167	Shared Neighborhood Hits	12
SwissProt Accessions	O15240	Gene names	VGF
Domain Architecture	No domain graphic available
Description	Neurosecretory protein VGF precursor.

CMTA2_MOUSE
NC score	0.023120 (rank : 145)	θ value	0.0252991 (rank : 91)
Query Neighborhood Hits	212	Target Neighborhood Hits	216	Shared Neighborhood Hits	9
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

E2F4_HUMAN
NC score	0.021779 (rank : 146)	θ value	0.0431538 (rank : 95)
Query Neighborhood Hits	212	Target Neighborhood Hits	188	Shared Neighborhood Hits	8
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

SI1L1_MOUSE
NC score	0.020748 (rank : 147)	θ value	0.0330416 (rank : 93)
Query Neighborhood Hits	212	Target Neighborhood Hits	189	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

TCOF_HUMAN
NC score	0.020657 (rank : 148)	θ value	0.125558 (rank : 103)
Query Neighborhood Hits	212	Target Neighborhood Hits	543	Shared Neighborhood Hits	25
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

ACINU_MOUSE
NC score	0.020049 (rank : 149)	θ value	0.0148317 (rank : 85)
Query Neighborhood Hits	212	Target Neighborhood Hits	712	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

SI1L1_HUMAN
NC score	0.019915 (rank : 150)	θ value	0.0961366 (rank : 101)
Query Neighborhood Hits	212	Target Neighborhood Hits	162	Shared Neighborhood Hits	5
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

PRG4_HUMAN
NC score	0.019915 (rank : 151)	θ value	0.00869519 (rank : 84)
Query Neighborhood Hits	212	Target Neighborhood Hits	764	Shared Neighborhood Hits	33
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SRRM2_MOUSE
NC score	0.018799 (rank : 152)	θ value	0.21417 (rank : 106)
Query Neighborhood Hits	212	Target Neighborhood Hits	1470	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

CENPC_HUMAN
NC score	0.018587 (rank : 153)	θ value	0.279714 (rank : 108)
Query Neighborhood Hits	212	Target Neighborhood Hits	147	Shared Neighborhood Hits	4
SwissProt Accessions	Q03188, Q9P0M5	Gene names	CENPC1, CENPC, ICEN7
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C) (Interphase centromere complex protein 7).

KI67_HUMAN
NC score	0.018232 (rank : 154)	θ value	0.813845 (rank : 120)
Query Neighborhood Hits	212	Target Neighborhood Hits	581	Shared Neighborhood Hits	24
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

SRRM2_HUMAN
NC score	0.017778 (rank : 155)	θ value	1.38821 (rank : 136)
Query Neighborhood Hits	212	Target Neighborhood Hits	1296	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

MAP4_MOUSE
NC score	0.016707 (rank : 156)	θ value	4.03905 (rank : 169)
Query Neighborhood Hits	212	Target Neighborhood Hits	409	Shared Neighborhood Hits	26
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

PDZD2_HUMAN
NC score	0.016396 (rank : 157)	θ value	0.0736092 (rank : 100)
Query Neighborhood Hits	212	Target Neighborhood Hits	772	Shared Neighborhood Hits	33
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

FA21C_HUMAN
NC score	0.016022 (rank : 158)	θ value	1.06291 (rank : 124)
Query Neighborhood Hits	212	Target Neighborhood Hits	194	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

MDC1_HUMAN
NC score	0.014612 (rank : 159)	θ value	1.06291 (rank : 131)
Query Neighborhood Hits	212	Target Neighborhood Hits	1446	Shared Neighborhood Hits	45
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

GP179_HUMAN
NC score	0.013939 (rank : 160)	θ value	1.81305 (rank : 140)
Query Neighborhood Hits	212	Target Neighborhood Hits	372	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

FETUB_HUMAN
NC score	0.013896 (rank : 161)	θ value	1.06291 (rank : 125)
Query Neighborhood Hits	212	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UGM5, Q1RMZ0, Q6DK58, Q6GRB6, Q9Y6Z0	Gene names	FETUB
Domain Architecture
Description	Fetuin-B precursor (Gugu) (IRL685) (16G2).

SON_MOUSE
NC score	0.013788 (rank : 162)	θ value	0.813845 (rank : 121)
Query Neighborhood Hits	212	Target Neighborhood Hits	957	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

DNL3_HUMAN
NC score	0.013315 (rank : 163)	θ value	1.06291 (rank : 123)
Query Neighborhood Hits	212	Target Neighborhood Hits	49	Shared Neighborhood Hits	7
SwissProt Accessions	P49916, Q16714	Gene names	LIG3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

MDC1_MOUSE
NC score	0.012621 (rank : 164)	θ value	6.88961 (rank : 188)
Query Neighborhood Hits	212	Target Neighborhood Hits	998	Shared Neighborhood Hits	45
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

GSCR1_HUMAN
NC score	0.012609 (rank : 165)	θ value	1.81305 (rank : 141)
Query Neighborhood Hits	212	Target Neighborhood Hits	674	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

AHTF1_HUMAN
NC score	0.011250 (rank : 166)	θ value	1.38821 (rank : 133)
Query Neighborhood Hits	212	Target Neighborhood Hits	286	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WYP5, Q7Z4E3, Q8IZA4, Q96EH9, Q9Y4Q6	Gene names	AHCTF1, ELYS, TMBS62
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

YLPM1_HUMAN
NC score	0.010524 (rank : 167)	θ value	5.27518 (rank : 181)
Query Neighborhood Hits	212	Target Neighborhood Hits	670	Shared Neighborhood Hits	26
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

ECM1_HUMAN
NC score	0.010263 (rank : 168)	θ value	3.0926 (rank : 149)
Query Neighborhood Hits	212	Target Neighborhood Hits	182	Shared Neighborhood Hits	11
SwissProt Accessions	Q16610	Gene names	ECM1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

RECQ4_MOUSE
NC score	0.009895 (rank : 169)	θ value	0.47712 (rank : 114)
Query Neighborhood Hits	212	Target Neighborhood Hits	206	Shared Neighborhood Hits	7
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

ANLN_HUMAN
NC score	0.009256 (rank : 170)	θ value	2.36792 (rank : 145)
Query Neighborhood Hits	212	Target Neighborhood Hits	222	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

CC062_HUMAN
NC score	0.008780 (rank : 171)	θ value	5.27518 (rank : 173)
Query Neighborhood Hits	212	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZUJ4, Q6P7E9, Q7Z3X6	Gene names	C3orf62
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf62.

SFRS4_MOUSE
NC score	0.008382 (rank : 172)	θ value	0.365318 (rank : 111)
Query Neighborhood Hits	212	Target Neighborhood Hits	406	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

SGIP1_HUMAN
NC score	0.008328 (rank : 173)	θ value	6.88961 (rank : 194)
Query Neighborhood Hits	212	Target Neighborhood Hits	198	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

MIER1_HUMAN
NC score	0.008213 (rank : 174)	θ value	3.0926 (rank : 155)
Query Neighborhood Hits	212	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N108, Q5T104, Q6AHY8, Q86TB4, Q8N156, Q8N161, Q8NC37, Q8NES4, Q8NES5, Q8NES6, Q8WWG2, Q9HCG2	Gene names	MIER1, KIAA1610
Domain Architecture	No domain graphic available
Description	Mesoderm induction early response protein 1 (Mi-er1) (hmi-er1) (Early response 1) (Er1).

SMOO_HUMAN
NC score	0.007917 (rank : 175)	θ value	4.03905 (rank : 170)
Query Neighborhood Hits	212	Target Neighborhood Hits	391	Shared Neighborhood Hits	21
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

TGON2_HUMAN
NC score	0.007874 (rank : 176)	θ value	8.99809 (rank : 212)
Query Neighborhood Hits	212	Target Neighborhood Hits	1037	Shared Neighborhood Hits	44
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

RGS3_MOUSE
NC score	0.007837 (rank : 177)	θ value	1.06291 (rank : 132)
Query Neighborhood Hits	212	Target Neighborhood Hits	1621	Shared Neighborhood Hits	53
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

CBL_HUMAN
NC score	0.007772 (rank : 178)	θ value	1.06291 (rank : 122)
Query Neighborhood Hits	212	Target Neighborhood Hits	353	Shared Neighborhood Hits	11
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

LARP4_HUMAN
NC score	0.007630 (rank : 179)	θ value	5.27518 (rank : 177)
Query Neighborhood Hits	212	Target Neighborhood Hits	69	Shared Neighborhood Hits	8
SwissProt Accessions	Q71RC2, Q5CZ97, Q96NF9	Gene names	LARP4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

ZC3H3_HUMAN
NC score	0.007478 (rank : 180)	θ value	4.03905 (rank : 171)
Query Neighborhood Hits	212	Target Neighborhood Hits	159	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IXZ2, Q14163, Q8N4E2, Q9BUS4	Gene names	ZC3H3, KIAA0150, ZC3HDC3
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

PININ_HUMAN
NC score	0.007063 (rank : 181)	θ value	8.99809 (rank : 206)
Query Neighborhood Hits	212	Target Neighborhood Hits	753	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

ESCO1_HUMAN
NC score	0.006840 (rank : 182)	θ value	5.27518 (rank : 174)
Query Neighborhood Hits	212	Target Neighborhood Hits	361	Shared Neighborhood Hits	17
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

ELOA1_MOUSE
NC score	0.006584 (rank : 183)	θ value	4.03905 (rank : 159)
Query Neighborhood Hits	212	Target Neighborhood Hits	152	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CB77, Q80VB2, Q9R0Q5	Gene names	Tceb3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

LRRF1_MOUSE
NC score	0.006044 (rank : 184)	θ value	3.0926 (rank : 153)
Query Neighborhood Hits	212	Target Neighborhood Hits	440	Shared Neighborhood Hits	14
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

MLL4_HUMAN
NC score	0.005926 (rank : 185)	θ value	3.0926 (rank : 156)
Query Neighborhood Hits	212	Target Neighborhood Hits	722	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

REXO1_MOUSE
NC score	0.005741 (rank : 186)	θ value	5.27518 (rank : 179)
Query Neighborhood Hits	212	Target Neighborhood Hits	166	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TT28, Q3UMP1, Q69ZR0, Q6NSQ6, Q6PI95, Q9DA29	Gene names	Rexo1, Kiaa1138, Tceb3bp1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1).

RBBP6_HUMAN
NC score	0.005712 (rank : 187)	θ value	6.88961 (rank : 192)
Query Neighborhood Hits	212	Target Neighborhood Hits	1135	Shared Neighborhood Hits	41
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

SAPS1_HUMAN
NC score	0.005653 (rank : 188)	θ value	8.99809 (rank : 207)
Query Neighborhood Hits	212	Target Neighborhood Hits	704	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

P3H3_MOUSE
NC score	0.005644 (rank : 189)	θ value	3.0926 (rank : 157)
Query Neighborhood Hits	212	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CG70, O88836	Gene names	Leprel2, P3h3
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 3 precursor (EC 1.14.11.7) (Leprecan-like protein 2) (Protein B).

HTSF1_MOUSE
NC score	0.005306 (rank : 190)	θ value	4.03905 (rank : 160)
Query Neighborhood Hits	212	Target Neighborhood Hits	425	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

PCLO_MOUSE
NC score	0.005128 (rank : 191)	θ value	3.0926 (rank : 158)
Query Neighborhood Hits	212	Target Neighborhood Hits	2275	Shared Neighborhood Hits	55
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

ABCC8_HUMAN
NC score	0.004943 (rank : 192)	θ value	3.0926 (rank : 148)
Query Neighborhood Hits	212	Target Neighborhood Hits	118	Shared Neighborhood Hits	6
SwissProt Accessions	Q09428, O75948, Q16583	Gene names	ABCC8, SUR, SUR1
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 8 (Sulfonylurea receptor 1).

RERE_HUMAN
NC score	0.004668 (rank : 193)	θ value	6.88961 (rank : 193)
Query Neighborhood Hits	212	Target Neighborhood Hits	779	Shared Neighborhood Hits	28
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

CN092_MOUSE
NC score	0.004651 (rank : 194)	θ value	8.99809 (rank : 199)
Query Neighborhood Hits	212	Target Neighborhood Hits	206	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

CN092_HUMAN
NC score	0.004497 (rank : 195)	θ value	8.99809 (rank : 198)
Query Neighborhood Hits	212	Target Neighborhood Hits	143	Shared Neighborhood Hits	8
SwissProt Accessions	O94842	Gene names	C14orf92, KIAA0737
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

SPRL1_MOUSE
NC score	0.003919 (rank : 196)	θ value	5.27518 (rank : 180)
Query Neighborhood Hits	212	Target Neighborhood Hits	403	Shared Neighborhood Hits	14
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

SFPQ_HUMAN
NC score	0.003577 (rank : 197)	θ value	2.36792 (rank : 147)
Query Neighborhood Hits	212	Target Neighborhood Hits	986	Shared Neighborhood Hits	26
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

MINT_HUMAN
NC score	0.003519 (rank : 198)	θ value	5.27518 (rank : 178)
Query Neighborhood Hits	212	Target Neighborhood Hits	1291	Shared Neighborhood Hits	39
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SENP3_MOUSE
NC score	0.003066 (rank : 199)	θ value	8.99809 (rank : 208)
Query Neighborhood Hits	212	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EP97	Gene names	Senp3, Smt3ip, Smt3ip1
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3) (Smt3-specific isopeptidase 1) (Smt3ip1).

AP3B1_MOUSE
NC score	0.002876 (rank : 200)	θ value	5.27518 (rank : 172)
Query Neighborhood Hits	212	Target Neighborhood Hits	302	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

ABCC9_HUMAN
NC score	0.002798 (rank : 201)	θ value	6.88961 (rank : 182)
Query Neighborhood Hits	212	Target Neighborhood Hits	108	Shared Neighborhood Hits	4
SwissProt Accessions	O60706, O60707	Gene names	ABCC9, SUR2
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 9 (Sulfonylurea receptor 2).

ABCC9_MOUSE
NC score	0.002739 (rank : 202)	θ value	6.88961 (rank : 183)
Query Neighborhood Hits	212	Target Neighborhood Hits	110	Shared Neighborhood Hits	4
SwissProt Accessions	P70170, O08902, O08920, P70171	Gene names	Abcc9, Sur2
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 9 (Sulfonylurea receptor 2).

PLCB3_MOUSE
NC score	0.002685 (rank : 203)	θ value	6.88961 (rank : 191)
Query Neighborhood Hits	212	Target Neighborhood Hits	344	Shared Neighborhood Hits	7
SwissProt Accessions	P51432	Gene names	Plcb3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

T2R41_HUMAN
NC score	0.002548 (rank : 204)	θ value	1.81305 (rank : 144)
Query Neighborhood Hits	212	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	P59536, P59550	Gene names	TAS2R41
Domain Architecture
Description	Taste receptor type 2 member 41 (T2R41) (T2R59).

PLCB3_HUMAN
NC score	0.002451 (rank : 205)	θ value	6.88961 (rank : 190)
Query Neighborhood Hits	212	Target Neighborhood Hits	445	Shared Neighborhood Hits	9
SwissProt Accessions	Q01970	Gene names	PLCB3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

NARGL_MOUSE
NC score	0.002111 (rank : 206)	θ value	8.99809 (rank : 205)
Query Neighborhood Hits	212	Target Neighborhood Hits	175	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBB4, Q3U7V2	Gene names	Narg1l, Nat2
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated 1-like protein (NARG1-like protein).

NOP14_HUMAN
NC score	0.001578 (rank : 207)	θ value	6.88961 (rank : 189)
Query Neighborhood Hits	212	Target Neighborhood Hits	573	Shared Neighborhood Hits	11
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

LAP4_MOUSE
NC score	0.001022 (rank : 208)	θ value	0.47712 (rank : 113)
Query Neighborhood Hits	212	Target Neighborhood Hits	590	Shared Neighborhood Hits	11
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

SYTL2_MOUSE
NC score	0.000479 (rank : 209)	θ value	8.99809 (rank : 210)
Query Neighborhood Hits	212	Target Neighborhood Hits	253	Shared Neighborhood Hits	7
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

TACC2_MOUSE
NC score	0.000274 (rank : 210)	θ value	8.99809 (rank : 211)
Query Neighborhood Hits	212	Target Neighborhood Hits	774	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

CEND3_MOUSE
NC score	-0.000171 (rank : 211)	θ value	8.99809 (rank : 197)
Query Neighborhood Hits	212	Target Neighborhood Hits	228	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

MEGF9_HUMAN
NC score	-0.000474 (rank : 212)	θ value	3.0926 (rank : 154)
Query Neighborhood Hits	212	Target Neighborhood Hits	557	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

ESX1L_HUMAN
NC score	-0.001316 (rank : 213)	θ value	1.81305 (rank : 139)
Query Neighborhood Hits	212	Target Neighborhood Hits	498	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N693, Q7Z6K7	Gene names	ESX1L, ESX1R
Domain Architecture
Description	Extraembryonic, spermatogenesis, homeobox 1-like protein.

AATK_MOUSE
NC score	-0.002457 (rank : 214)	θ value	1.81305 (rank : 138)
Query Neighborhood Hits	212	Target Neighborhood Hits	942	Shared Neighborhood Hits	17
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

PTPRF_HUMAN
NC score	-0.002644 (rank : 215)	θ value	1.81305 (rank : 143)
Query Neighborhood Hits	212	Target Neighborhood Hits	489	Shared Neighborhood Hits	2
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

FES_HUMAN
NC score	-0.003348 (rank : 216)	θ value	0.125558 (rank : 102)
Query Neighborhood Hits	212	Target Neighborhood Hits	978	Shared Neighborhood Hits	9
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

M3K14_MOUSE
NC score	-0.003574 (rank : 217)	θ value	0.62314 (rank : 115)
Query Neighborhood Hits	212	Target Neighborhood Hits	889	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WUL6	Gene names	Map3k14, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK).

FES_MOUSE
NC score	-0.003954 (rank : 218)	θ value	0.813845 (rank : 117)
Query Neighborhood Hits	212	Target Neighborhood Hits	980	Shared Neighborhood Hits	6
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

AN30A_HUMAN
NC score	-0.004181 (rank : 219)	θ value	6.88961 (rank : 184)
Query Neighborhood Hits	212	Target Neighborhood Hits	1119	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ZN687_HUMAN
NC score	-0.004576 (rank : 220)	θ value	6.88961 (rank : 196)
Query Neighborhood Hits	212	Target Neighborhood Hits	1244	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

ZBT45_HUMAN
NC score	-0.005950 (rank : 221)	θ value	1.38821 (rank : 137)
Query Neighborhood Hits	212	Target Neighborhood Hits	901	Shared Neighborhood Hits	10
SwissProt Accessions	Q96K62	Gene names	ZBTB45, ZNF499
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 45 (Zinc finger protein 499).

SN1L1_MOUSE
NC score	-0.007026 (rank : 222)	θ value	8.99809 (rank : 209)
Query Neighborhood Hits	212	Target Neighborhood Hits	895	Shared Neighborhood Hits	10
SwissProt Accessions	Q60670	Gene names	Snf1lk, Msk
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1- like kinase).

ZN628_HUMAN
NC score	-0.007145 (rank : 223)	θ value	6.88961 (rank : 195)
Query Neighborhood Hits	212	Target Neighborhood Hits	814	Shared Neighborhood Hits	7
SwissProt Accessions	Q5EBL2, Q86X34	Gene names	ZNF628
Domain Architecture	No domain graphic available
Description	Zinc finger protein 628.