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Network neighborhood for query Sequence : MEGF9_HUMAN

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MEGF9_HUMAN
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MEGF9_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	557	Target Neighborhood Hits	557	Shared Neighborhood Hits	557
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEGF9_MOUSE
θ value	0 (rank : 2)	NC score	0.923296 (rank : 2)
Query Neighborhood Hits	557	Target Neighborhood Hits	896	Shared Neighborhood Hits	364
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

LAMB1_HUMAN
θ value	3.60269e-49 (rank : 3)	NC score	0.792852 (rank : 21)
Query Neighborhood Hits	557	Target Neighborhood Hits	1018	Shared Neighborhood Hits	283
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB2_MOUSE
θ value	3.60269e-49 (rank : 4)	NC score	0.867212 (rank : 4)
Query Neighborhood Hits	557	Target Neighborhood Hits	722	Shared Neighborhood Hits	287
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMB2_HUMAN
θ value	4.70527e-49 (rank : 5)	NC score	0.867529 (rank : 3)
Query Neighborhood Hits	557	Target Neighborhood Hits	692	Shared Neighborhood Hits	282
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB1_MOUSE
θ value	6.14528e-49 (rank : 6)	NC score	0.821651 (rank : 13)
Query Neighborhood Hits	557	Target Neighborhood Hits	919	Shared Neighborhood Hits	273
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMA2_MOUSE
θ value	1.62093e-41 (rank : 7)	NC score	0.759333 (rank : 32)
Query Neighborhood Hits	557	Target Neighborhood Hits	1198	Shared Neighborhood Hits	302
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA1_MOUSE
θ value	3.61106e-41 (rank : 8)	NC score	0.832799 (rank : 11)
Query Neighborhood Hits	557	Target Neighborhood Hits	838	Shared Neighborhood Hits	314
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

USH2A_HUMAN
θ value	6.81017e-40 (rank : 9)	NC score	0.738328 (rank : 37)
Query Neighborhood Hits	557	Target Neighborhood Hits	600	Shared Neighborhood Hits	272
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

LAMA2_HUMAN
θ value	7.52953e-39 (rank : 10)	NC score	0.786998 (rank : 25)
Query Neighborhood Hits	557	Target Neighborhood Hits	1092	Shared Neighborhood Hits	305
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA1_HUMAN
θ value	4.88048e-38 (rank : 11)	NC score	0.835900 (rank : 10)
Query Neighborhood Hits	557	Target Neighborhood Hits	804	Shared Neighborhood Hits	305
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

USH2A_MOUSE
θ value	4.88048e-38 (rank : 12)	NC score	0.754809 (rank : 33)
Query Neighborhood Hits	557	Target Neighborhood Hits	626	Shared Neighborhood Hits	283
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

LAMC1_MOUSE
θ value	5.96599e-36 (rank : 13)	NC score	0.807976 (rank : 15)
Query Neighborhood Hits	557	Target Neighborhood Hits	856	Shared Neighborhood Hits	288
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMA5_HUMAN
θ value	2.50655e-34 (rank : 14)	NC score	0.851616 (rank : 8)
Query Neighborhood Hits	557	Target Neighborhood Hits	976	Shared Neighborhood Hits	323
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMA5_MOUSE
θ value	6.17384e-33 (rank : 15)	NC score	0.860843 (rank : 7)
Query Neighborhood Hits	557	Target Neighborhood Hits	828	Shared Neighborhood Hits	322
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMC1_HUMAN
θ value	6.17384e-33 (rank : 16)	NC score	0.783854 (rank : 29)
Query Neighborhood Hits	557	Target Neighborhood Hits	922	Shared Neighborhood Hits	286
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC3_MOUSE
θ value	1.37539e-32 (rank : 17)	NC score	0.863816 (rank : 5)
Query Neighborhood Hits	557	Target Neighborhood Hits	624	Shared Neighborhood Hits	299
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMA4_MOUSE
θ value	1.52067e-31 (rank : 18)	NC score	0.734721 (rank : 39)
Query Neighborhood Hits	557	Target Neighborhood Hits	584	Shared Neighborhood Hits	205
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA4_HUMAN
θ value	1.28732e-30 (rank : 19)	NC score	0.694624 (rank : 43)
Query Neighborhood Hits	557	Target Neighborhood Hits	708	Shared Neighborhood Hits	202
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMC3_HUMAN
θ value	1.6813e-30 (rank : 20)	NC score	0.863346 (rank : 6)
Query Neighborhood Hits	557	Target Neighborhood Hits	588	Shared Neighborhood Hits	297
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMA3_MOUSE
θ value	2.68423e-28 (rank : 21)	NC score	0.787977 (rank : 24)
Query Neighborhood Hits	557	Target Neighborhood Hits	859	Shared Neighborhood Hits	295
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LAMC2_HUMAN
θ value	2.96777e-27 (rank : 22)	NC score	0.789359 (rank : 23)
Query Neighborhood Hits	557	Target Neighborhood Hits	715	Shared Neighborhood Hits	277
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LAMC2_MOUSE
θ value	1.92365e-26 (rank : 23)	NC score	0.818895 (rank : 14)
Query Neighborhood Hits	557	Target Neighborhood Hits	614	Shared Neighborhood Hits	283
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LAMB3_MOUSE
θ value	4.28545e-26 (rank : 24)	NC score	0.845123 (rank : 9)
Query Neighborhood Hits	557	Target Neighborhood Hits	444	Shared Neighborhood Hits	229
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LAMB3_HUMAN
θ value	2.77775e-25 (rank : 25)	NC score	0.830362 (rank : 12)
Query Neighborhood Hits	557	Target Neighborhood Hits	461	Shared Neighborhood Hits	204
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

PGBM_MOUSE
θ value	7.56453e-23 (rank : 26)	NC score	0.555934 (rank : 91)
Query Neighborhood Hits	557	Target Neighborhood Hits	1073	Shared Neighborhood Hits	310
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGBM_HUMAN
θ value	9.87957e-23 (rank : 27)	NC score	0.541667 (rank : 99)
Query Neighborhood Hits	557	Target Neighborhood Hits	1113	Shared Neighborhood Hits	316
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

LAMA3_HUMAN
θ value	1.09232e-21 (rank : 28)	NC score	0.714236 (rank : 41)
Query Neighborhood Hits	557	Target Neighborhood Hits	760	Shared Neighborhood Hits	240
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

NET4_MOUSE
θ value	9.24701e-21 (rank : 29)	NC score	0.786765 (rank : 27)
Query Neighborhood Hits	557	Target Neighborhood Hits	180	Shared Neighborhood Hits	157
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

NET4_HUMAN
θ value	4.58923e-20 (rank : 30)	NC score	0.786997 (rank : 26)
Query Neighborhood Hits	557	Target Neighborhood Hits	191	Shared Neighborhood Hits	160
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

MEGF8_HUMAN
θ value	1.02238e-19 (rank : 31)	NC score	0.744235 (rank : 36)
Query Neighborhood Hits	557	Target Neighborhood Hits	528	Shared Neighborhood Hits	283
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_MOUSE
θ value	1.74391e-19 (rank : 32)	NC score	0.733072 (rank : 40)
Query Neighborhood Hits	557	Target Neighborhood Hits	520	Shared Neighborhood Hits	277
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF6_HUMAN
θ value	1.13037e-18 (rank : 33)	NC score	0.713180 (rank : 42)
Query Neighborhood Hits	557	Target Neighborhood Hits	671	Shared Neighborhood Hits	318
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

SREC2_HUMAN
θ value	9.56915e-18 (rank : 34)	NC score	0.801257 (rank : 16)
Query Neighborhood Hits	557	Target Neighborhood Hits	645	Shared Neighborhood Hits	337
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

NET1_MOUSE
θ value	1.63225e-17 (rank : 35)	NC score	0.747750 (rank : 35)
Query Neighborhood Hits	557	Target Neighborhood Hits	151	Shared Neighborhood Hits	127
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

SREC2_MOUSE
θ value	1.63225e-17 (rank : 36)	NC score	0.799871 (rank : 17)
Query Neighborhood Hits	557	Target Neighborhood Hits	605	Shared Neighborhood Hits	326
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SREC_HUMAN
θ value	3.63628e-17 (rank : 37)	NC score	0.784296 (rank : 28)
Query Neighborhood Hits	557	Target Neighborhood Hits	645	Shared Neighborhood Hits	319
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

AGRIN_HUMAN
θ value	4.74913e-17 (rank : 38)	NC score	0.735318 (rank : 38)
Query Neighborhood Hits	557	Target Neighborhood Hits	582	Shared Neighborhood Hits	300
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

NET1_HUMAN
θ value	4.74913e-17 (rank : 39)	NC score	0.750037 (rank : 34)
Query Neighborhood Hits	557	Target Neighborhood Hits	149	Shared Neighborhood Hits	127
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

NET2_MOUSE
θ value	6.20254e-17 (rank : 40)	NC score	0.774288 (rank : 30)
Query Neighborhood Hits	557	Target Neighborhood Hits	193	Shared Neighborhood Hits	161
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

NET2_HUMAN
θ value	1.058e-16 (rank : 41)	NC score	0.772764 (rank : 31)
Query Neighborhood Hits	557	Target Neighborhood Hits	194	Shared Neighborhood Hits	156
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

NTNG1_MOUSE
θ value	1.38178e-16 (rank : 42)	NC score	0.793145 (rank : 20)
Query Neighborhood Hits	557	Target Neighborhood Hits	246	Shared Neighborhood Hits	197
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG1_HUMAN
θ value	3.07829e-16 (rank : 43)	NC score	0.794052 (rank : 19)
Query Neighborhood Hits	557	Target Neighborhood Hits	247	Shared Neighborhood Hits	197
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

CELR1_MOUSE
θ value	1.09485e-13 (rank : 44)	NC score	0.367183 (rank : 200)
Query Neighborhood Hits	557	Target Neighborhood Hits	617	Shared Neighborhood Hits	246
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

NTNG2_MOUSE
θ value	1.86753e-13 (rank : 45)	NC score	0.790709 (rank : 22)
Query Neighborhood Hits	557	Target Neighborhood Hits	276	Shared Neighborhood Hits	217
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

NTNG2_HUMAN
θ value	3.18553e-13 (rank : 46)	NC score	0.796103 (rank : 18)
Query Neighborhood Hits	557	Target Neighborhood Hits	276	Shared Neighborhood Hits	208
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

CELR1_HUMAN
θ value	4.16044e-13 (rank : 47)	NC score	0.368231 (rank : 198)
Query Neighborhood Hits	557	Target Neighborhood Hits	613	Shared Neighborhood Hits	242
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CELR3_MOUSE
θ value	5.43371e-13 (rank : 48)	NC score	0.379489 (rank : 193)
Query Neighborhood Hits	557	Target Neighborhood Hits	687	Shared Neighborhood Hits	265
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

CELR2_HUMAN
θ value	2.0648e-12 (rank : 49)	NC score	0.381571 (rank : 191)
Query Neighborhood Hits	557	Target Neighborhood Hits	657	Shared Neighborhood Hits	259
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CELR3_HUMAN
θ value	2.69671e-12 (rank : 50)	NC score	0.381380 (rank : 192)
Query Neighborhood Hits	557	Target Neighborhood Hits	680	Shared Neighborhood Hits	262
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CELR2_MOUSE
θ value	3.52202e-12 (rank : 51)	NC score	0.362349 (rank : 202)
Query Neighborhood Hits	557	Target Neighborhood Hits	584	Shared Neighborhood Hits	242
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

PCSK5_MOUSE
θ value	6.00763e-12 (rank : 52)	NC score	0.495187 (rank : 119)
Query Neighborhood Hits	557	Target Neighborhood Hits	613	Shared Neighborhood Hits	298
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

CREL1_MOUSE
θ value	7.84624e-12 (rank : 53)	NC score	0.587928 (rank : 82)
Query Neighborhood Hits	557	Target Neighborhood Hits	524	Shared Neighborhood Hits	245
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_HUMAN
θ value	1.33837e-11 (rank : 54)	NC score	0.612406 (rank : 73)
Query Neighborhood Hits	557	Target Neighborhood Hits	441	Shared Neighborhood Hits	243
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

NOTC1_HUMAN
θ value	1.74796e-11 (rank : 55)	NC score	0.589118 (rank : 81)
Query Neighborhood Hits	557	Target Neighborhood Hits	906	Shared Neighborhood Hits	304
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

STAB2_MOUSE
θ value	1.74796e-11 (rank : 56)	NC score	0.639790 (rank : 57)
Query Neighborhood Hits	557	Target Neighborhood Hits	528	Shared Neighborhood Hits	308
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

NOTC4_MOUSE
θ value	5.08577e-11 (rank : 57)	NC score	0.572819 (rank : 87)
Query Neighborhood Hits	557	Target Neighborhood Hits	872	Shared Neighborhood Hits	293
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

JAG1_MOUSE
θ value	6.64225e-11 (rank : 58)	NC score	0.649243 (rank : 50)
Query Neighborhood Hits	557	Target Neighborhood Hits	518	Shared Neighborhood Hits	283
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG1_HUMAN
θ value	8.67504e-11 (rank : 59)	NC score	0.648593 (rank : 51)
Query Neighborhood Hits	557	Target Neighborhood Hits	514	Shared Neighborhood Hits	286
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

NOTC1_MOUSE
θ value	1.133e-10 (rank : 60)	NC score	0.605234 (rank : 77)
Query Neighborhood Hits	557	Target Neighborhood Hits	916	Shared Neighborhood Hits	308
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

ATRN_HUMAN
θ value	1.9326e-10 (rank : 61)	NC score	0.608603 (rank : 74)
Query Neighborhood Hits	557	Target Neighborhood Hits	525	Shared Neighborhood Hits	240
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

FRAS1_MOUSE
θ value	1.9326e-10 (rank : 62)	NC score	0.455308 (rank : 144)
Query Neighborhood Hits	557	Target Neighborhood Hits	747	Shared Neighborhood Hits	280
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

LTBP2_MOUSE
θ value	1.9326e-10 (rank : 63)	NC score	0.532364 (rank : 102)
Query Neighborhood Hits	557	Target Neighborhood Hits	617	Shared Neighborhood Hits	301
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

STAB2_HUMAN
θ value	1.9326e-10 (rank : 64)	NC score	0.640800 (rank : 56)
Query Neighborhood Hits	557	Target Neighborhood Hits	534	Shared Neighborhood Hits	297
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

STAB1_MOUSE
θ value	2.52405e-10 (rank : 65)	NC score	0.637824 (rank : 60)
Query Neighborhood Hits	557	Target Neighborhood Hits	566	Shared Neighborhood Hits	305
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

DLL1_HUMAN
θ value	7.34386e-10 (rank : 66)	NC score	0.650223 (rank : 49)
Query Neighborhood Hits	557	Target Neighborhood Hits	455	Shared Neighborhood Hits	281
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

NOTC3_MOUSE
θ value	9.59137e-10 (rank : 67)	NC score	0.586680 (rank : 84)
Query Neighborhood Hits	557	Target Neighborhood Hits	975	Shared Neighborhood Hits	316
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

FRAS1_HUMAN
θ value	1.63604e-09 (rank : 68)	NC score	0.470225 (rank : 130)
Query Neighborhood Hits	557	Target Neighborhood Hits	759	Shared Neighborhood Hits	290
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

SLIT2_MOUSE
θ value	1.63604e-09 (rank : 69)	NC score	0.445674 (rank : 151)
Query Neighborhood Hits	557	Target Neighborhood Hits	684	Shared Neighborhood Hits	257
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

STAB1_HUMAN
θ value	1.63604e-09 (rank : 70)	NC score	0.642591 (rank : 54)
Query Neighborhood Hits	557	Target Neighborhood Hits	546	Shared Neighborhood Hits	300
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

ATRN_MOUSE
θ value	3.64472e-09 (rank : 71)	NC score	0.607993 (rank : 75)
Query Neighborhood Hits	557	Target Neighborhood Hits	519	Shared Neighborhood Hits	237
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

DLL4_HUMAN
θ value	6.21693e-09 (rank : 72)	NC score	0.653683 (rank : 48)
Query Neighborhood Hits	557	Target Neighborhood Hits	435	Shared Neighborhood Hits	278
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

ITB5_HUMAN
θ value	6.21693e-09 (rank : 73)	NC score	0.500217 (rank : 113)
Query Neighborhood Hits	557	Target Neighborhood Hits	310	Shared Neighborhood Hits	225
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

DLL1_MOUSE
θ value	8.11959e-09 (rank : 74)	NC score	0.647440 (rank : 52)
Query Neighborhood Hits	557	Target Neighborhood Hits	456	Shared Neighborhood Hits	287
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

ITB3_HUMAN
θ value	8.11959e-09 (rank : 75)	NC score	0.481908 (rank : 123)
Query Neighborhood Hits	557	Target Neighborhood Hits	325	Shared Neighborhood Hits	226
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

SLIT2_HUMAN
θ value	8.11959e-09 (rank : 76)	NC score	0.451308 (rank : 147)
Query Neighborhood Hits	557	Target Neighborhood Hits	708	Shared Neighborhood Hits	262
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

NOTC2_HUMAN
θ value	1.06045e-08 (rank : 77)	NC score	0.569790 (rank : 88)
Query Neighborhood Hits	557	Target Neighborhood Hits	1113	Shared Neighborhood Hits	330
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PCSK5_HUMAN
θ value	1.06045e-08 (rank : 78)	NC score	0.322226 (rank : 227)
Query Neighborhood Hits	557	Target Neighborhood Hits	291	Shared Neighborhood Hits	184
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

SLIT3_HUMAN
θ value	1.06045e-08 (rank : 79)	NC score	0.435786 (rank : 160)
Query Neighborhood Hits	557	Target Neighborhood Hits	682	Shared Neighborhood Hits	257
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

ITB5_MOUSE
θ value	1.38499e-08 (rank : 80)	NC score	0.510702 (rank : 111)
Query Neighborhood Hits	557	Target Neighborhood Hits	329	Shared Neighborhood Hits	232
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

DNER_HUMAN
θ value	2.36244e-08 (rank : 81)	NC score	0.638581 (rank : 59)
Query Neighborhood Hits	557	Target Neighborhood Hits	460	Shared Neighborhood Hits	269
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

JAG2_HUMAN
θ value	3.08544e-08 (rank : 82)	NC score	0.638895 (rank : 58)
Query Neighborhood Hits	557	Target Neighborhood Hits	491	Shared Neighborhood Hits	277
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

LTBP2_HUMAN
θ value	3.08544e-08 (rank : 83)	NC score	0.528640 (rank : 105)
Query Neighborhood Hits	557	Target Neighborhood Hits	552	Shared Neighborhood Hits	301
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

CRUM1_MOUSE
θ value	4.0297e-08 (rank : 84)	NC score	0.629271 (rank : 66)
Query Neighborhood Hits	557	Target Neighborhood Hits	444	Shared Neighborhood Hits	261
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

DNER_MOUSE
θ value	5.26297e-08 (rank : 85)	NC score	0.636591 (rank : 62)
Query Neighborhood Hits	557	Target Neighborhood Hits	413	Shared Neighborhood Hits	260
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

FBN2_HUMAN
θ value	5.26297e-08 (rank : 86)	NC score	0.528353 (rank : 106)
Query Neighborhood Hits	557	Target Neighborhood Hits	560	Shared Neighborhood Hits	295
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

MUC1_HUMAN
θ value	5.26297e-08 (rank : 87)	NC score	0.076093 (rank : 580)
Query Neighborhood Hits	557	Target Neighborhood Hits	975	Shared Neighborhood Hits	106
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

FBN1_HUMAN
θ value	6.87365e-08 (rank : 88)	NC score	0.529068 (rank : 104)
Query Neighborhood Hits	557	Target Neighborhood Hits	557	Shared Neighborhood Hits	302
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

NOTC2_MOUSE
θ value	6.87365e-08 (rank : 89)	NC score	0.575009 (rank : 86)
Query Neighborhood Hits	557	Target Neighborhood Hits	1069	Shared Neighborhood Hits	313
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

TENA_MOUSE
θ value	6.87365e-08 (rank : 90)	NC score	0.543225 (rank : 97)
Query Neighborhood Hits	557	Target Neighborhood Hits	596	Shared Neighborhood Hits	282
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TIE1_HUMAN
θ value	6.87365e-08 (rank : 91)	NC score	0.237346 (rank : 290)
Query Neighborhood Hits	557	Target Neighborhood Hits	1241	Shared Neighborhood Hits	258
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

NOTC3_HUMAN
θ value	8.97725e-08 (rank : 92)	NC score	0.587342 (rank : 83)
Query Neighborhood Hits	557	Target Neighborhood Hits	1062	Shared Neighborhood Hits	323
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

DLL4_MOUSE
θ value	1.53129e-07 (rank : 93)	NC score	0.656618 (rank : 47)
Query Neighborhood Hits	557	Target Neighborhood Hits	440	Shared Neighborhood Hits	280
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

SLIT1_MOUSE
θ value	1.53129e-07 (rank : 94)	NC score	0.464676 (rank : 136)
Query Neighborhood Hits	557	Target Neighborhood Hits	715	Shared Neighborhood Hits	267
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

DLK_HUMAN
θ value	1.99992e-07 (rank : 95)	NC score	0.657108 (rank : 46)
Query Neighborhood Hits	557	Target Neighborhood Hits	401	Shared Neighborhood Hits	267
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

FBN2_MOUSE
θ value	2.61198e-07 (rank : 96)	NC score	0.526462 (rank : 107)
Query Neighborhood Hits	557	Target Neighborhood Hits	549	Shared Neighborhood Hits	292
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

KRA53_HUMAN
θ value	3.41135e-07 (rank : 97)	NC score	0.659338 (rank : 45)
Query Neighborhood Hits	557	Target Neighborhood Hits	331	Shared Neighborhood Hits	207
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

TENA_HUMAN
θ value	3.41135e-07 (rank : 98)	NC score	0.543241 (rank : 96)
Query Neighborhood Hits	557	Target Neighborhood Hits	631	Shared Neighborhood Hits	284
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

NOTC4_HUMAN
θ value	4.45536e-07 (rank : 99)	NC score	0.569424 (rank : 89)
Query Neighborhood Hits	557	Target Neighborhood Hits	905	Shared Neighborhood Hits	299
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

TIE2_MOUSE
θ value	4.45536e-07 (rank : 100)	NC score	0.213122 (rank : 310)
Query Neighborhood Hits	557	Target Neighborhood Hits	1204	Shared Neighborhood Hits	252
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

ITB6_HUMAN
θ value	5.81887e-07 (rank : 101)	NC score	0.503185 (rank : 112)
Query Neighborhood Hits	557	Target Neighborhood Hits	318	Shared Neighborhood Hits	230
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

JAG2_MOUSE
θ value	7.59969e-07 (rank : 102)	NC score	0.637744 (rank : 61)
Query Neighborhood Hits	557	Target Neighborhood Hits	504	Shared Neighborhood Hits	280
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

TIE1_MOUSE
θ value	7.59969e-07 (rank : 103)	NC score	0.230307 (rank : 298)
Query Neighborhood Hits	557	Target Neighborhood Hits	1266	Shared Neighborhood Hits	252
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE2_HUMAN
θ value	7.59969e-07 (rank : 104)	NC score	0.210779 (rank : 312)
Query Neighborhood Hits	557	Target Neighborhood Hits	1192	Shared Neighborhood Hits	243
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

FBN3_HUMAN
θ value	9.92553e-07 (rank : 105)	NC score	0.533784 (rank : 101)
Query Neighborhood Hits	557	Target Neighborhood Hits	543	Shared Neighborhood Hits	286
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

ITB3_MOUSE
θ value	9.92553e-07 (rank : 106)	NC score	0.469135 (rank : 132)
Query Neighborhood Hits	557	Target Neighborhood Hits	319	Shared Neighborhood Hits	218
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB6_MOUSE
θ value	9.92553e-07 (rank : 107)	NC score	0.510811 (rank : 110)
Query Neighborhood Hits	557	Target Neighborhood Hits	341	Shared Neighborhood Hits	235
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

SLIT3_MOUSE
θ value	1.29631e-06 (rank : 108)	NC score	0.440512 (rank : 156)
Query Neighborhood Hits	557	Target Neighborhood Hits	700	Shared Neighborhood Hits	268
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

EGFL9_MOUSE
θ value	1.69304e-06 (rank : 109)	NC score	0.620022 (rank : 72)
Query Neighborhood Hits	557	Target Neighborhood Hits	379	Shared Neighborhood Hits	259
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

MATN2_HUMAN
θ value	1.69304e-06 (rank : 110)	NC score	0.395824 (rank : 181)
Query Neighborhood Hits	557	Target Neighborhood Hits	365	Shared Neighborhood Hits	202
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

EGFL9_HUMAN
θ value	2.21117e-06 (rank : 111)	NC score	0.628968 (rank : 67)
Query Neighborhood Hits	557	Target Neighborhood Hits	365	Shared Neighborhood Hits	257
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

SLIT1_HUMAN
θ value	2.21117e-06 (rank : 112)	NC score	0.461674 (rank : 139)
Query Neighborhood Hits	557	Target Neighborhood Hits	700	Shared Neighborhood Hits	260
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

WIF1_MOUSE
θ value	2.88788e-06 (rank : 113)	NC score	0.646294 (rank : 53)
Query Neighborhood Hits	557	Target Neighborhood Hits	393	Shared Neighborhood Hits	264
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

LRP1_HUMAN
θ value	3.77169e-06 (rank : 114)	NC score	0.453008 (rank : 146)
Query Neighborhood Hits	557	Target Neighborhood Hits	617	Shared Neighborhood Hits	291
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

TENX_HUMAN
θ value	3.77169e-06 (rank : 115)	NC score	0.546653 (rank : 94)
Query Neighborhood Hits	557	Target Neighborhood Hits	789	Shared Neighborhood Hits	309
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

CRUM1_HUMAN
θ value	6.43352e-06 (rank : 116)	NC score	0.625999 (rank : 69)
Query Neighborhood Hits	557	Target Neighborhood Hits	457	Shared Neighborhood Hits	261
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

SCUB3_MOUSE
θ value	6.43352e-06 (rank : 117)	NC score	0.484327 (rank : 121)
Query Neighborhood Hits	557	Target Neighborhood Hits	442	Shared Neighborhood Hits	261
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

WIF1_HUMAN
θ value	8.40245e-06 (rank : 118)	NC score	0.635536 (rank : 63)
Query Neighborhood Hits	557	Target Neighborhood Hits	392	Shared Neighborhood Hits	265
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

FBN1_MOUSE
θ value	1.09739e-05 (rank : 119)	NC score	0.530271 (rank : 103)
Query Neighborhood Hits	557	Target Neighborhood Hits	563	Shared Neighborhood Hits	303
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

LTBP3_HUMAN
θ value	1.43324e-05 (rank : 120)	NC score	0.497362 (rank : 118)
Query Neighborhood Hits	557	Target Neighborhood Hits	502	Shared Neighborhood Hits	273
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

KR511_HUMAN
θ value	1.87187e-05 (rank : 121)	NC score	0.542011 (rank : 98)
Query Neighborhood Hits	557	Target Neighborhood Hits	231	Shared Neighborhood Hits	140
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

DLL3_MOUSE
θ value	2.44474e-05 (rank : 122)	NC score	0.628434 (rank : 68)
Query Neighborhood Hits	557	Target Neighborhood Hits	399	Shared Neighborhood Hits	255
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

FATH_HUMAN
θ value	2.44474e-05 (rank : 123)	NC score	0.324500 (rank : 221)
Query Neighborhood Hits	557	Target Neighborhood Hits	570	Shared Neighborhood Hits	239
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

NELL2_HUMAN
θ value	2.44474e-05 (rank : 124)	NC score	0.515007 (rank : 108)
Query Neighborhood Hits	557	Target Neighborhood Hits	449	Shared Neighborhood Hits	264
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

SCUB3_HUMAN
θ value	2.44474e-05 (rank : 125)	NC score	0.483985 (rank : 122)
Query Neighborhood Hits	557	Target Neighborhood Hits	428	Shared Neighborhood Hits	255
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

KRA59_HUMAN
θ value	3.19293e-05 (rank : 126)	NC score	0.631650 (rank : 65)
Query Neighborhood Hits	557	Target Neighborhood Hits	310	Shared Neighborhood Hits	182
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

LRP1B_HUMAN
θ value	3.19293e-05 (rank : 127)	NC score	0.438922 (rank : 158)
Query Neighborhood Hits	557	Target Neighborhood Hits	602	Shared Neighborhood Hits	286
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1B_MOUSE
θ value	3.19293e-05 (rank : 128)	NC score	0.435792 (rank : 159)
Query Neighborhood Hits	557	Target Neighborhood Hits	606	Shared Neighborhood Hits	284
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

NAGPA_MOUSE
θ value	4.1701e-05 (rank : 129)	NC score	0.600817 (rank : 80)
Query Neighborhood Hits	557	Target Neighborhood Hits	308	Shared Neighborhood Hits	216
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NACAM_MOUSE
θ value	5.44631e-05 (rank : 130)	NC score	0.098448 (rank : 489)
Query Neighborhood Hits	557	Target Neighborhood Hits	1866	Shared Neighborhood Hits	181
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

KRA55_HUMAN
θ value	9.29e-05 (rank : 131)	NC score	0.623810 (rank : 70)
Query Neighborhood Hits	557	Target Neighborhood Hits	257	Shared Neighborhood Hits	166
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA58_HUMAN
θ value	9.29e-05 (rank : 132)	NC score	0.607799 (rank : 76)
Query Neighborhood Hits	557	Target Neighborhood Hits	324	Shared Neighborhood Hits	195
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

MATN2_MOUSE
θ value	9.29e-05 (rank : 133)	NC score	0.382806 (rank : 190)
Query Neighborhood Hits	557	Target Neighborhood Hits	356	Shared Neighborhood Hits	198
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

PCSK6_HUMAN
θ value	9.29e-05 (rank : 134)	NC score	0.284976 (rank : 251)
Query Neighborhood Hits	557	Target Neighborhood Hits	298	Shared Neighborhood Hits	168
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

TNR3_HUMAN
θ value	9.29e-05 (rank : 135)	NC score	0.156432 (rank : 356)
Query Neighborhood Hits	557	Target Neighborhood Hits	145	Shared Neighborhood Hits	76
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

DLL3_HUMAN
θ value	0.000121331 (rank : 136)	NC score	0.634828 (rank : 64)
Query Neighborhood Hits	557	Target Neighborhood Hits	419	Shared Neighborhood Hits	259
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

LTBP3_MOUSE
θ value	0.000121331 (rank : 137)	NC score	0.498098 (rank : 115)
Query Neighborhood Hits	557	Target Neighborhood Hits	475	Shared Neighborhood Hits	286
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP4_MOUSE
θ value	0.000121331 (rank : 138)	NC score	0.548509 (rank : 93)
Query Neighborhood Hits	557	Target Neighborhood Hits	607	Shared Neighborhood Hits	314
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

OGFR_HUMAN
θ value	0.000121331 (rank : 139)	NC score	0.058539 (rank : 707)
Query Neighborhood Hits	557	Target Neighborhood Hits	1582	Shared Neighborhood Hits	123
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PRRT3_HUMAN
θ value	0.000121331 (rank : 140)	NC score	0.062533 (rank : 672)
Query Neighborhood Hits	557	Target Neighborhood Hits	998	Shared Neighborhood Hits	88
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

CSPG3_MOUSE
θ value	0.000158464 (rank : 141)	NC score	0.357332 (rank : 205)
Query Neighborhood Hits	557	Target Neighborhood Hits	657	Shared Neighborhood Hits	251
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

DLK_MOUSE
θ value	0.000158464 (rank : 142)	NC score	0.642534 (rank : 55)
Query Neighborhood Hits	557	Target Neighborhood Hits	374	Shared Neighborhood Hits	259
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

FBLN1_MOUSE
θ value	0.000158464 (rank : 143)	NC score	0.432343 (rank : 165)
Query Neighborhood Hits	557	Target Neighborhood Hits	329	Shared Neighborhood Hits	214
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

MAGE1_HUMAN
θ value	0.000158464 (rank : 144)	NC score	0.072176 (rank : 600)
Query Neighborhood Hits	557	Target Neighborhood Hits	1389	Shared Neighborhood Hits	141
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

CEL_HUMAN
θ value	0.00020696 (rank : 145)	NC score	0.050237 (rank : 821)
Query Neighborhood Hits	557	Target Neighborhood Hits	896	Shared Neighborhood Hits	96
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CRUM2_HUMAN
θ value	0.00020696 (rank : 146)	NC score	0.623267 (rank : 71)
Query Neighborhood Hits	557	Target Neighborhood Hits	453	Shared Neighborhood Hits	267
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

KRA54_HUMAN
θ value	0.00020696 (rank : 147)	NC score	0.601232 (rank : 79)
Query Neighborhood Hits	557	Target Neighborhood Hits	270	Shared Neighborhood Hits	170
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

LYAM2_MOUSE
θ value	0.00020696 (rank : 148)	NC score	0.287237 (rank : 248)
Query Neighborhood Hits	557	Target Neighborhood Hits	420	Shared Neighborhood Hits	203
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

MDC1_HUMAN
θ value	0.00020696 (rank : 149)	NC score	0.095427 (rank : 498)
Query Neighborhood Hits	557	Target Neighborhood Hits	1446	Shared Neighborhood Hits	138
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

TENR_HUMAN
θ value	0.00020696 (rank : 150)	NC score	0.386940 (rank : 186)
Query Neighborhood Hits	557	Target Neighborhood Hits	526	Shared Neighborhood Hits	257
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

ITB2_MOUSE
θ value	0.000270298 (rank : 151)	NC score	0.498774 (rank : 114)
Query Neighborhood Hits	557	Target Neighborhood Hits	326	Shared Neighborhood Hits	236
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

TENR_MOUSE
θ value	0.000270298 (rank : 152)	NC score	0.392855 (rank : 182)
Query Neighborhood Hits	557	Target Neighborhood Hits	531	Shared Neighborhood Hits	260
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

ADA22_MOUSE
θ value	0.00035302 (rank : 153)	NC score	0.120694 (rank : 413)
Query Neighborhood Hits	557	Target Neighborhood Hits	225	Shared Neighborhood Hits	117
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

KRA57_HUMAN
θ value	0.00035302 (rank : 154)	NC score	0.602857 (rank : 78)
Query Neighborhood Hits	557	Target Neighborhood Hits	269	Shared Neighborhood Hits	172
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

ITB7_MOUSE
θ value	0.000461057 (rank : 155)	NC score	0.498074 (rank : 116)
Query Neighborhood Hits	557	Target Neighborhood Hits	277	Shared Neighborhood Hits	202
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

CSPG2_HUMAN
θ value	0.000602161 (rank : 156)	NC score	0.336090 (rank : 218)
Query Neighborhood Hits	557	Target Neighborhood Hits	681	Shared Neighborhood Hits	235
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

SON_HUMAN
θ value	0.000602161 (rank : 157)	NC score	0.069258 (rank : 620)
Query Neighborhood Hits	557	Target Neighborhood Hits	1568	Shared Neighborhood Hits	137
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

COMP_HUMAN
θ value	0.000786445 (rank : 158)	NC score	0.434417 (rank : 163)
Query Neighborhood Hits	557	Target Neighborhood Hits	258	Shared Neighborhood Hits	190
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

ITB7_HUMAN
θ value	0.000786445 (rank : 159)	NC score	0.498008 (rank : 117)
Query Neighborhood Hits	557	Target Neighborhood Hits	290	Shared Neighborhood Hits	212
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

PROS_MOUSE
θ value	0.000786445 (rank : 160)	NC score	0.445631 (rank : 152)
Query Neighborhood Hits	557	Target Neighborhood Hits	330	Shared Neighborhood Hits	215
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

FHL5_MOUSE
θ value	0.00102713 (rank : 161)	NC score	0.063235 (rank : 660)
Query Neighborhood Hits	557	Target Neighborhood Hits	463	Shared Neighborhood Hits	40
SwissProt Accessions	Q9WTX7	Gene names	Fhl5, Act
Domain Architecture	No domain graphic available
Description	Four and a half LIM domains protein 5 (FHL-5) (Activator of cAMP- responsive element modulator in testis) (Activator of CREM in testis).

KRA51_HUMAN
θ value	0.00102713 (rank : 162)	NC score	0.683152 (rank : 44)
Query Neighborhood Hits	557	Target Neighborhood Hits	288	Shared Neighborhood Hits	183
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

LRP2_HUMAN
θ value	0.00102713 (rank : 163)	NC score	0.368169 (rank : 199)
Query Neighborhood Hits	557	Target Neighborhood Hits	573	Shared Neighborhood Hits	284
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

PROS_HUMAN
θ value	0.00102713 (rank : 164)	NC score	0.453423 (rank : 145)
Query Neighborhood Hits	557	Target Neighborhood Hits	340	Shared Neighborhood Hits	224
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

TARSH_HUMAN
θ value	0.00102713 (rank : 165)	NC score	0.114326 (rank : 430)
Query Neighborhood Hits	557	Target Neighborhood Hits	768	Shared Neighborhood Hits	126
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

CUBN_HUMAN
θ value	0.00134147 (rank : 166)	NC score	0.473431 (rank : 126)
Query Neighborhood Hits	557	Target Neighborhood Hits	482	Shared Neighborhood Hits	252
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

FBLN1_HUMAN
θ value	0.00134147 (rank : 167)	NC score	0.416889 (rank : 171)
Query Neighborhood Hits	557	Target Neighborhood Hits	324	Shared Neighborhood Hits	218
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

LTB1L_MOUSE
θ value	0.00134147 (rank : 168)	NC score	0.470510 (rank : 129)
Query Neighborhood Hits	557	Target Neighborhood Hits	514	Shared Neighborhood Hits	272
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	0.00134147 (rank : 169)	NC score	0.469997 (rank : 131)
Query Neighborhood Hits	557	Target Neighborhood Hits	479	Shared Neighborhood Hits	260
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

ATF6B_HUMAN
θ value	0.00175202 (rank : 170)	NC score	0.039584 (rank : 846)
Query Neighborhood Hits	557	Target Neighborhood Hits	122	Shared Neighborhood Hits	18
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).

ITB2_HUMAN
θ value	0.00175202 (rank : 171)	NC score	0.472131 (rank : 127)
Query Neighborhood Hits	557	Target Neighborhood Hits	282	Shared Neighborhood Hits	214
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB4_HUMAN
θ value	0.00175202 (rank : 172)	NC score	0.450448 (rank : 148)
Query Neighborhood Hits	557	Target Neighborhood Hits	458	Shared Neighborhood Hits	238
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

ADA22_HUMAN
θ value	0.00228821 (rank : 173)	NC score	0.107553 (rank : 449)
Query Neighborhood Hits	557	Target Neighborhood Hits	211	Shared Neighborhood Hits	111
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

FHL5_HUMAN
θ value	0.00228821 (rank : 174)	NC score	0.061756 (rank : 676)
Query Neighborhood Hits	557	Target Neighborhood Hits	523	Shared Neighborhood Hits	51
SwissProt Accessions	Q5TD97, Q5TD98, Q8WW21, Q9NQU2	Gene names	FHL5, ACT
Domain Architecture	No domain graphic available
Description	Four and a half LIM domains protein 5 (FHL-5) (Activator of cAMP- responsive element modulator in testis) (Activator of CREM in testis).

LYAM3_MOUSE
θ value	0.00228821 (rank : 175)	NC score	0.265737 (rank : 274)
Query Neighborhood Hits	557	Target Neighborhood Hits	390	Shared Neighborhood Hits	185
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MKS3_HUMAN
θ value	0.00228821 (rank : 176)	NC score	0.197545 (rank : 319)
Query Neighborhood Hits	557	Target Neighborhood Hits	79	Shared Neighborhood Hits	68
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

NAGPA_HUMAN
θ value	0.00228821 (rank : 177)	NC score	0.581791 (rank : 85)
Query Neighborhood Hits	557	Target Neighborhood Hits	282	Shared Neighborhood Hits	200
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

SELPL_MOUSE
θ value	0.00228821 (rank : 178)	NC score	0.085335 (rank : 526)
Query Neighborhood Hits	557	Target Neighborhood Hits	588	Shared Neighborhood Hits	87
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

ADAM7_MOUSE
θ value	0.00298849 (rank : 179)	NC score	0.096790 (rank : 495)
Query Neighborhood Hits	557	Target Neighborhood Hits	200	Shared Neighborhood Hits	118
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

CRIM1_HUMAN
θ value	0.00298849 (rank : 180)	NC score	0.456942 (rank : 142)
Query Neighborhood Hits	557	Target Neighborhood Hits	362	Shared Neighborhood Hits	194
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

FBLN3_HUMAN
θ value	0.00298849 (rank : 181)	NC score	0.373034 (rank : 195)
Query Neighborhood Hits	557	Target Neighborhood Hits	293	Shared Neighborhood Hits	195
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

TSP3_HUMAN
θ value	0.00298849 (rank : 182)	NC score	0.405672 (rank : 177)
Query Neighborhood Hits	557	Target Neighborhood Hits	250	Shared Neighborhood Hits	172
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

FBLN2_MOUSE
θ value	0.00390308 (rank : 183)	NC score	0.442359 (rank : 155)
Query Neighborhood Hits	557	Target Neighborhood Hits	505	Shared Neighborhood Hits	254
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

ITB1_MOUSE
θ value	0.00390308 (rank : 184)	NC score	0.465411 (rank : 134)
Query Neighborhood Hits	557	Target Neighborhood Hits	283	Shared Neighborhood Hits	198
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

SORL_HUMAN
θ value	0.00390308 (rank : 185)	NC score	0.251502 (rank : 283)
Query Neighborhood Hits	557	Target Neighborhood Hits	440	Shared Neighborhood Hits	202
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

CU030_HUMAN
θ value	0.00509761 (rank : 186)	NC score	0.058423 (rank : 709)
Query Neighborhood Hits	557	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UFM2	Gene names	C21orf30
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C21orf30.

HHIP_HUMAN
θ value	0.00509761 (rank : 187)	NC score	0.486280 (rank : 120)
Query Neighborhood Hits	557	Target Neighborhood Hits	249	Shared Neighborhood Hits	199
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

KRA52_HUMAN
θ value	0.00509761 (rank : 188)	NC score	0.545020 (rank : 95)
Query Neighborhood Hits	557	Target Neighborhood Hits	236	Shared Neighborhood Hits	153
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

LYAM2_HUMAN
θ value	0.00509761 (rank : 189)	NC score	0.262735 (rank : 276)
Query Neighborhood Hits	557	Target Neighborhood Hits	394	Shared Neighborhood Hits	188
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

MUC13_HUMAN
θ value	0.00509761 (rank : 190)	NC score	0.194001 (rank : 323)
Query Neighborhood Hits	557	Target Neighborhood Hits	164	Shared Neighborhood Hits	102
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

NELL2_MOUSE
θ value	0.00509761 (rank : 191)	NC score	0.513400 (rank : 109)
Query Neighborhood Hits	557	Target Neighborhood Hits	436	Shared Neighborhood Hits	263
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

BSN_HUMAN
θ value	0.00665767 (rank : 192)	NC score	0.077056 (rank : 572)
Query Neighborhood Hits	557	Target Neighborhood Hits	1537	Shared Neighborhood Hits	152
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

KR510_HUMAN
θ value	0.00665767 (rank : 193)	NC score	0.563022 (rank : 90)
Query Neighborhood Hits	557	Target Neighborhood Hits	217	Shared Neighborhood Hits	135
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

MKS3_MOUSE
θ value	0.00665767 (rank : 194)	NC score	0.244556 (rank : 288)
Query Neighborhood Hits	557	Target Neighborhood Hits	89	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

NCOA6_MOUSE
θ value	0.00665767 (rank : 195)	NC score	0.074537 (rank : 590)
Query Neighborhood Hits	557	Target Neighborhood Hits	1076	Shared Neighborhood Hits	130
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

COMP_MOUSE
θ value	0.00869519 (rank : 196)	NC score	0.457770 (rank : 141)
Query Neighborhood Hits	557	Target Neighborhood Hits	290	Shared Neighborhood Hits	210
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

FAT2_HUMAN
θ value	0.00869519 (rank : 197)	NC score	0.218936 (rank : 306)
Query Neighborhood Hits	557	Target Neighborhood Hits	507	Shared Neighborhood Hits	187
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

ITB1_HUMAN
θ value	0.00869519 (rank : 198)	NC score	0.464291 (rank : 137)
Query Neighborhood Hits	557	Target Neighborhood Hits	298	Shared Neighborhood Hits	203
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

NELL1_HUMAN
θ value	0.00869519 (rank : 199)	NC score	0.536576 (rank : 100)
Query Neighborhood Hits	557	Target Neighborhood Hits	451	Shared Neighborhood Hits	267
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

PROC_MOUSE
θ value	0.00869519 (rank : 200)	NC score	0.161213 (rank : 351)
Query Neighborhood Hits	557	Target Neighborhood Hits	426	Shared Neighborhood Hits	181
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

TSP1_MOUSE
θ value	0.00869519 (rank : 201)	NC score	0.310210 (rank : 234)
Query Neighborhood Hits	557	Target Neighborhood Hits	396	Shared Neighborhood Hits	213
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP3_MOUSE
θ value	0.00869519 (rank : 202)	NC score	0.416649 (rank : 172)
Query Neighborhood Hits	557	Target Neighborhood Hits	247	Shared Neighborhood Hits	178
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

EPHA7_HUMAN
θ value	0.0113563 (rank : 203)	NC score	0.071060 (rank : 608)
Query Neighborhood Hits	557	Target Neighborhood Hits	1053	Shared Neighborhood Hits	135
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

HCFC1_MOUSE
θ value	0.0113563 (rank : 204)	NC score	0.092668 (rank : 508)
Query Neighborhood Hits	557	Target Neighborhood Hits	348	Shared Neighborhood Hits	78
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

KRA56_HUMAN
θ value	0.0113563 (rank : 205)	NC score	0.552771 (rank : 92)
Query Neighborhood Hits	557	Target Neighborhood Hits	207	Shared Neighborhood Hits	138
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

TSP1_HUMAN
θ value	0.0113563 (rank : 206)	NC score	0.305638 (rank : 236)
Query Neighborhood Hits	557	Target Neighborhood Hits	389	Shared Neighborhood Hits	211
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

ZNF45_HUMAN
θ value	0.0113563 (rank : 207)	NC score	0.009409 (rank : 942)
Query Neighborhood Hits	557	Target Neighborhood Hits	773	Shared Neighborhood Hits	52
SwissProt Accessions	Q02386, P78472, Q9P1U9	Gene names	ZNF45
Domain Architecture
Description	Zinc finger protein 45 (BRC1744).

CK024_MOUSE
θ value	0.0148317 (rank : 208)	NC score	0.081278 (rank : 547)
Query Neighborhood Hits	557	Target Neighborhood Hits	307	Shared Neighborhood Hits	63
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

HHIP_MOUSE
θ value	0.0148317 (rank : 209)	NC score	0.466424 (rank : 133)
Query Neighborhood Hits	557	Target Neighborhood Hits	219	Shared Neighborhood Hits	178
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

KR106_HUMAN
θ value	0.0148317 (rank : 210)	NC score	0.447358 (rank : 150)
Query Neighborhood Hits	557	Target Neighborhood Hits	347	Shared Neighborhood Hits	203
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

NID2_HUMAN
θ value	0.0148317 (rank : 211)	NC score	0.428309 (rank : 166)
Query Neighborhood Hits	557	Target Neighborhood Hits	456	Shared Neighborhood Hits	224
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

PGCA_HUMAN
θ value	0.0148317 (rank : 212)	NC score	0.168066 (rank : 343)
Query Neighborhood Hits	557	Target Neighborhood Hits	821	Shared Neighborhood Hits	205
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

THYG_HUMAN
θ value	0.0148317 (rank : 213)	NC score	0.086224 (rank : 523)
Query Neighborhood Hits	557	Target Neighborhood Hits	154	Shared Neighborhood Hits	70
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

TRBM_HUMAN
θ value	0.0148317 (rank : 214)	NC score	0.424139 (rank : 168)
Query Neighborhood Hits	557	Target Neighborhood Hits	339	Shared Neighborhood Hits	203
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

WNK2_HUMAN
θ value	0.0148317 (rank : 215)	NC score	0.025191 (rank : 880)
Query Neighborhood Hits	557	Target Neighborhood Hits	1407	Shared Neighborhood Hits	149
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

CSPG2_MOUSE
θ value	0.0193708 (rank : 216)	NC score	0.339388 (rank : 216)
Query Neighborhood Hits	557	Target Neighborhood Hits	711	Shared Neighborhood Hits	242
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

EPHA2_HUMAN
θ value	0.0193708 (rank : 217)	NC score	0.061575 (rank : 678)
Query Neighborhood Hits	557	Target Neighborhood Hits	1021	Shared Neighborhood Hits	103
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

EPHA3_MOUSE
θ value	0.0193708 (rank : 218)	NC score	0.065070 (rank : 647)
Query Neighborhood Hits	557	Target Neighborhood Hits	1009	Shared Neighborhood Hits	104
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

FHL2_HUMAN
θ value	0.0193708 (rank : 219)	NC score	0.057116 (rank : 727)
Query Neighborhood Hits	557	Target Neighborhood Hits	533	Shared Neighborhood Hits	51
SwissProt Accessions	Q14192, Q13229, Q13644, Q9P294	Gene names	FHL2, DRAL, SLIM3
Domain Architecture
Description	Four and a half LIM domains protein 2 (FHL-2) (Skeletal muscle LIM- protein 3) (SLIM 3) (LIM-domain protein DRAL).

HCFC1_HUMAN
θ value	0.0193708 (rank : 220)	NC score	0.094815 (rank : 502)
Query Neighborhood Hits	557	Target Neighborhood Hits	331	Shared Neighborhood Hits	77
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

MATN3_MOUSE
θ value	0.0193708 (rank : 221)	NC score	0.299346 (rank : 240)
Query Neighborhood Hits	557	Target Neighborhood Hits	261	Shared Neighborhood Hits	157
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

PF21B_MOUSE
θ value	0.0193708 (rank : 222)	NC score	0.042830 (rank : 836)
Query Neighborhood Hits	557	Target Neighborhood Hits	278	Shared Neighborhood Hits	51
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

THYG_MOUSE
θ value	0.0193708 (rank : 223)	NC score	0.076525 (rank : 578)
Query Neighborhood Hits	557	Target Neighborhood Hits	161	Shared Neighborhood Hits	72
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

TNR1B_HUMAN
θ value	0.0193708 (rank : 224)	NC score	0.119073 (rank : 416)
Query Neighborhood Hits	557	Target Neighborhood Hits	127	Shared Neighborhood Hits	77
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TSP4_MOUSE
θ value	0.0193708 (rank : 225)	NC score	0.439316 (rank : 157)
Query Neighborhood Hits	557	Target Neighborhood Hits	276	Shared Neighborhood Hits	207
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

ZAN_MOUSE
θ value	0.0193708 (rank : 226)	NC score	0.472080 (rank : 128)
Query Neighborhood Hits	557	Target Neighborhood Hits	808	Shared Neighborhood Hits	342
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

ANK2_HUMAN
θ value	0.0252991 (rank : 227)	NC score	0.039579 (rank : 847)
Query Neighborhood Hits	557	Target Neighborhood Hits	1615	Shared Neighborhood Hits	114
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

C1QR1_MOUSE
θ value	0.0252991 (rank : 228)	NC score	0.427743 (rank : 167)
Query Neighborhood Hits	557	Target Neighborhood Hits	342	Shared Neighborhood Hits	213
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

EPHA3_HUMAN
θ value	0.0252991 (rank : 229)	NC score	0.062810 (rank : 666)
Query Neighborhood Hits	557	Target Neighborhood Hits	1005	Shared Neighborhood Hits	106
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

EPHAA_HUMAN
θ value	0.0252991 (rank : 230)	NC score	0.068267 (rank : 623)
Query Neighborhood Hits	557	Target Neighborhood Hits	960	Shared Neighborhood Hits	93
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

EPHB4_HUMAN
θ value	0.0252991 (rank : 231)	NC score	0.084179 (rank : 531)
Query Neighborhood Hits	557	Target Neighborhood Hits	1056	Shared Neighborhood Hits	156
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

KR10B_HUMAN
θ value	0.0252991 (rank : 232)	NC score	0.342692 (rank : 213)
Query Neighborhood Hits	557	Target Neighborhood Hits	269	Shared Neighborhood Hits	149
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

LTB1L_HUMAN
θ value	0.0252991 (rank : 233)	NC score	0.480406 (rank : 124)
Query Neighborhood Hits	557	Target Neighborhood Hits	553	Shared Neighborhood Hits	283
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	0.0252991 (rank : 234)	NC score	0.479146 (rank : 125)
Query Neighborhood Hits	557	Target Neighborhood Hits	502	Shared Neighborhood Hits	267
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LYAM3_HUMAN
θ value	0.0252991 (rank : 235)	NC score	0.252075 (rank : 282)
Query Neighborhood Hits	557	Target Neighborhood Hits	378	Shared Neighborhood Hits	182
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

SH23A_HUMAN
θ value	0.0252991 (rank : 236)	NC score	0.022439 (rank : 892)
Query Neighborhood Hits	557	Target Neighborhood Hits	149	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BRG2, Q9Y2X4	Gene names	SH2D3A, NSP1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3A (Novel SH2-containing protein 1).

SSPO_MOUSE
θ value	0.0252991 (rank : 237)	NC score	0.314510 (rank : 230)
Query Neighborhood Hits	557	Target Neighborhood Hits	800	Shared Neighborhood Hits	314
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

TNR14_HUMAN
θ value	0.0252991 (rank : 238)	NC score	0.216019 (rank : 308)
Query Neighborhood Hits	557	Target Neighborhood Hits	149	Shared Neighborhood Hits	95
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

BSN_MOUSE
θ value	0.0330416 (rank : 239)	NC score	0.076995 (rank : 573)
Query Neighborhood Hits	557	Target Neighborhood Hits	2057	Shared Neighborhood Hits	162
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

KR109_HUMAN
θ value	0.0330416 (rank : 240)	NC score	0.350229 (rank : 209)
Query Neighborhood Hits	557	Target Neighborhood Hits	226	Shared Neighborhood Hits	136
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

LPP_HUMAN
θ value	0.0330416 (rank : 241)	NC score	0.041828 (rank : 840)
Query Neighborhood Hits	557	Target Neighborhood Hits	775	Shared Neighborhood Hits	89
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

NPAS4_MOUSE
θ value	0.0330416 (rank : 242)	NC score	0.044228 (rank : 834)
Query Neighborhood Hits	557	Target Neighborhood Hits	245	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

ELTD1_HUMAN
θ value	0.0431538 (rank : 243)	NC score	0.224498 (rank : 301)
Query Neighborhood Hits	557	Target Neighborhood Hits	269	Shared Neighborhood Hits	143
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

EPHB6_MOUSE
θ value	0.0431538 (rank : 244)	NC score	0.064258 (rank : 651)
Query Neighborhood Hits	557	Target Neighborhood Hits	906	Shared Neighborhood Hits	99
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

FHL3_MOUSE
θ value	0.0431538 (rank : 245)	NC score	0.091263 (rank : 511)
Query Neighborhood Hits	557	Target Neighborhood Hits	424	Shared Neighborhood Hits	56
SwissProt Accessions	Q9R059, Q9JLP5, Q9WUH3	Gene names	Fhl3
Domain Architecture
Description	Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM- protein 2) (SLIM 2).

MATN3_HUMAN
θ value	0.0431538 (rank : 246)	NC score	0.300516 (rank : 239)
Query Neighborhood Hits	557	Target Neighborhood Hits	268	Shared Neighborhood Hits	157
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

PARM1_MOUSE
θ value	0.0431538 (rank : 247)	NC score	0.078363 (rank : 564)
Query Neighborhood Hits	557	Target Neighborhood Hits	140	Shared Neighborhood Hits	39
SwissProt Accessions	Q923D3, Q3TTV0, Q3UFU4	Gene names
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

TM108_MOUSE
θ value	0.0431538 (rank : 248)	NC score	0.078553 (rank : 563)
Query Neighborhood Hits	557	Target Neighborhood Hits	336	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TNR23_MOUSE
θ value	0.0431538 (rank : 249)	NC score	0.236386 (rank : 291)
Query Neighborhood Hits	557	Target Neighborhood Hits	114	Shared Neighborhood Hits	78
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

C1QR1_HUMAN
θ value	0.0563607 (rank : 250)	NC score	0.435084 (rank : 162)
Query Neighborhood Hits	557	Target Neighborhood Hits	493	Shared Neighborhood Hits	252
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

MDC1_MOUSE
θ value	0.0563607 (rank : 251)	NC score	0.080870 (rank : 551)
Query Neighborhood Hits	557	Target Neighborhood Hits	998	Shared Neighborhood Hits	122
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

NFRKB_MOUSE
θ value	0.0563607 (rank : 252)	NC score	0.067443 (rank : 628)
Query Neighborhood Hits	557	Target Neighborhood Hits	393	Shared Neighborhood Hits	73
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

NID2_MOUSE
θ value	0.0563607 (rank : 253)	NC score	0.401930 (rank : 179)
Query Neighborhood Hits	557	Target Neighborhood Hits	338	Shared Neighborhood Hits	204
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NPAS4_HUMAN
θ value	0.0563607 (rank : 254)	NC score	0.044310 (rank : 833)
Query Neighborhood Hits	557	Target Neighborhood Hits	214	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

PER3_HUMAN
θ value	0.0563607 (rank : 255)	NC score	0.047188 (rank : 829)
Query Neighborhood Hits	557	Target Neighborhood Hits	479	Shared Neighborhood Hits	71
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PI5PA_HUMAN
θ value	0.0563607 (rank : 256)	NC score	0.060289 (rank : 686)
Query Neighborhood Hits	557	Target Neighborhood Hits	749	Shared Neighborhood Hits	108
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

SORL_MOUSE
θ value	0.0563607 (rank : 257)	NC score	0.267165 (rank : 270)
Query Neighborhood Hits	557	Target Neighborhood Hits	439	Shared Neighborhood Hits	206
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

TNR16_HUMAN
θ value	0.0563607 (rank : 258)	NC score	0.281823 (rank : 257)
Query Neighborhood Hits	557	Target Neighborhood Hits	183	Shared Neighborhood Hits	117
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

ADA25_MOUSE
θ value	0.0736092 (rank : 259)	NC score	0.094694 (rank : 503)
Query Neighborhood Hits	557	Target Neighborhood Hits	213	Shared Neighborhood Hits	128
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

ADA28_MOUSE
θ value	0.0736092 (rank : 260)	NC score	0.101261 (rank : 476)
Query Neighborhood Hits	557	Target Neighborhood Hits	241	Shared Neighborhood Hits	132
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

CSPG3_HUMAN
θ value	0.0736092 (rank : 261)	NC score	0.346192 (rank : 210)
Query Neighborhood Hits	557	Target Neighborhood Hits	676	Shared Neighborhood Hits	240
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

EPHA2_MOUSE
θ value	0.0736092 (rank : 262)	NC score	0.062754 (rank : 668)
Query Neighborhood Hits	557	Target Neighborhood Hits	1020	Shared Neighborhood Hits	115
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

ERBB3_HUMAN
θ value	0.0736092 (rank : 263)	NC score	0.064104 (rank : 652)
Query Neighborhood Hits	557	Target Neighborhood Hits	918	Shared Neighborhood Hits	109
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

FBLN2_HUMAN
θ value	0.0736092 (rank : 264)	NC score	0.448840 (rank : 149)
Query Neighborhood Hits	557	Target Neighborhood Hits	392	Shared Neighborhood Hits	229
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

KR107_HUMAN
θ value	0.0736092 (rank : 265)	NC score	0.455885 (rank : 143)
Query Neighborhood Hits	557	Target Neighborhood Hits	330	Shared Neighborhood Hits	196
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

MYO15_HUMAN
θ value	0.0736092 (rank : 266)	NC score	0.017554 (rank : 913)
Query Neighborhood Hits	557	Target Neighborhood Hits	671	Shared Neighborhood Hits	92
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NFRKB_HUMAN
θ value	0.0736092 (rank : 267)	NC score	0.072053 (rank : 601)
Query Neighborhood Hits	557	Target Neighborhood Hits	211	Shared Neighborhood Hits	52
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

NRX2A_HUMAN
θ value	0.0736092 (rank : 268)	NC score	0.274111 (rank : 262)
Query Neighborhood Hits	557	Target Neighborhood Hits	614	Shared Neighborhood Hits	142
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	0.0736092 (rank : 269)	NC score	0.058179 (rank : 710)
Query Neighborhood Hits	557	Target Neighborhood Hits	481	Shared Neighborhood Hits	48
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

SPRR3_MOUSE
θ value	0.0736092 (rank : 270)	NC score	0.063531 (rank : 656)
Query Neighborhood Hits	557	Target Neighborhood Hits	106	Shared Neighborhood Hits	35
SwissProt Accessions	O09116	Gene names	Sprr3
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta).

TSP4_HUMAN
θ value	0.0736092 (rank : 271)	NC score	0.435232 (rank : 161)
Query Neighborhood Hits	557	Target Neighborhood Hits	277	Shared Neighborhood Hits	198
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

ZN155_HUMAN
θ value	0.0736092 (rank : 272)	NC score	0.006011 (rank : 959)
Query Neighborhood Hits	557	Target Neighborhood Hits	786	Shared Neighborhood Hits	54
SwissProt Accessions	Q12901, Q9UIE1, Q9UK14	Gene names	ZNF155
Domain Architecture
Description	Zinc finger protein 155.

ADA28_HUMAN
θ value	0.0961366 (rank : 273)	NC score	0.101771 (rank : 472)
Query Neighborhood Hits	557	Target Neighborhood Hits	244	Shared Neighborhood Hits	142
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

BCAR1_HUMAN
θ value	0.0961366 (rank : 274)	NC score	0.025194 (rank : 879)
Query Neighborhood Hits	557	Target Neighborhood Hits	554	Shared Neighborhood Hits	57
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CD248_HUMAN
θ value	0.0961366 (rank : 275)	NC score	0.337042 (rank : 217)
Query Neighborhood Hits	557	Target Neighborhood Hits	679	Shared Neighborhood Hits	239
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

FHL3_HUMAN
θ value	0.0961366 (rank : 276)	NC score	0.083428 (rank : 534)
Query Neighborhood Hits	557	Target Neighborhood Hits	354	Shared Neighborhood Hits	47
SwissProt Accessions	Q13643	Gene names	FHL3, SLIM2
Domain Architecture
Description	Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM- protein 2) (SLIM 2).

KR104_HUMAN
θ value	0.0961366 (rank : 277)	NC score	0.465236 (rank : 135)
Query Neighborhood Hits	557	Target Neighborhood Hits	313	Shared Neighborhood Hits	185
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR10C_HUMAN
θ value	0.0961366 (rank : 278)	NC score	0.342156 (rank : 214)
Query Neighborhood Hits	557	Target Neighborhood Hits	219	Shared Neighborhood Hits	134
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

LRP8_MOUSE
θ value	0.0961366 (rank : 279)	NC score	0.310453 (rank : 233)
Query Neighborhood Hits	557	Target Neighborhood Hits	385	Shared Neighborhood Hits	209
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

MUC24_HUMAN
θ value	0.0961366 (rank : 280)	NC score	0.070810 (rank : 610)
Query Neighborhood Hits	557	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q04900, Q5JSU6	Gene names	CD164
Domain Architecture
Description	Putative mucin core protein 24 precursor (Multi-glycosylated core protein 24) (MGC-24) (MUC-24) (CD164 antigen).

SMAL1_MOUSE
θ value	0.0961366 (rank : 281)	NC score	0.014587 (rank : 920)
Query Neighborhood Hits	557	Target Neighborhood Hits	157	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

ST14_HUMAN
θ value	0.0961366 (rank : 282)	NC score	0.082127 (rank : 542)
Query Neighborhood Hits	557	Target Neighborhood Hits	409	Shared Neighborhood Hits	128
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

CIZ1_HUMAN
θ value	0.125558 (rank : 283)	NC score	0.049554 (rank : 824)
Query Neighborhood Hits	557	Target Neighborhood Hits	359	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

EGFL7_HUMAN
θ value	0.125558 (rank : 284)	NC score	0.443653 (rank : 154)
Query Neighborhood Hits	557	Target Neighborhood Hits	325	Shared Neighborhood Hits	210
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EPHA7_MOUSE
θ value	0.125558 (rank : 285)	NC score	0.058170 (rank : 711)
Query Neighborhood Hits	557	Target Neighborhood Hits	1025	Shared Neighborhood Hits	108
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

EPHB6_HUMAN
θ value	0.125558 (rank : 286)	NC score	0.072688 (rank : 599)
Query Neighborhood Hits	557	Target Neighborhood Hits	912	Shared Neighborhood Hits	116
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

ERBB4_HUMAN
θ value	0.125558 (rank : 287)	NC score	0.059772 (rank : 692)
Query Neighborhood Hits	557	Target Neighborhood Hits	910	Shared Neighborhood Hits	98
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

FA10_MOUSE
θ value	0.125558 (rank : 288)	NC score	0.163637 (rank : 347)
Query Neighborhood Hits	557	Target Neighborhood Hits	435	Shared Neighborhood Hits	182
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

GA2L2_MOUSE
θ value	0.125558 (rank : 289)	NC score	0.028764 (rank : 870)
Query Neighborhood Hits	557	Target Neighborhood Hits	395	Shared Neighborhood Hits	52
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

KR101_HUMAN
θ value	0.125558 (rank : 290)	NC score	0.408731 (rank : 175)
Query Neighborhood Hits	557	Target Neighborhood Hits	261	Shared Neighborhood Hits	157
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR102_HUMAN
θ value	0.125558 (rank : 291)	NC score	0.370146 (rank : 197)
Query Neighborhood Hits	557	Target Neighborhood Hits	264	Shared Neighborhood Hits	152
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

MLL3_HUMAN
θ value	0.125558 (rank : 292)	NC score	0.078114 (rank : 566)
Query Neighborhood Hits	557	Target Neighborhood Hits	1644	Shared Neighborhood Hits	179
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PF21A_HUMAN
θ value	0.125558 (rank : 293)	NC score	0.028706 (rank : 871)
Query Neighborhood Hits	557	Target Neighborhood Hits	303	Shared Neighborhood Hits	27
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

TRML2_HUMAN
θ value	0.125558 (rank : 294)	NC score	0.029212 (rank : 868)
Query Neighborhood Hits	557	Target Neighborhood Hits	54	Shared Neighborhood Hits	7
SwissProt Accessions	Q5T2D2, Q8IWY0, Q9H8E9	Gene names	TREML2, C6orf76, TLT2
Domain Architecture	No domain graphic available
Description	Trem-like transcript 2 protein precursor (TLT-2) (Triggering receptor expressed on myeloid cells-like protein 2).

EPHA1_MOUSE
θ value	0.163984 (rank : 295)	NC score	0.059412 (rank : 695)
Query Neighborhood Hits	557	Target Neighborhood Hits	958	Shared Neighborhood Hits	112
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

K0319_MOUSE
θ value	0.163984 (rank : 296)	NC score	0.049142 (rank : 825)
Query Neighborhood Hits	557	Target Neighborhood Hits	134	Shared Neighborhood Hits	31
SwissProt Accessions	Q5SZV5, Q80U39	Gene names	Kiaa0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

PROZ_MOUSE
θ value	0.163984 (rank : 297)	NC score	0.307985 (rank : 235)
Query Neighborhood Hits	557	Target Neighborhood Hits	410	Shared Neighborhood Hits	183
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

VWF_MOUSE
θ value	0.163984 (rank : 298)	NC score	0.214175 (rank : 309)
Query Neighborhood Hits	557	Target Neighborhood Hits	381	Shared Neighborhood Hits	180
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

CK024_HUMAN
θ value	0.21417 (rank : 299)	NC score	0.112396 (rank : 435)
Query Neighborhood Hits	557	Target Neighborhood Hits	408	Shared Neighborhood Hits	81
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CUBN_MOUSE
θ value	0.21417 (rank : 300)	NC score	0.458551 (rank : 140)
Query Neighborhood Hits	557	Target Neighborhood Hits	477	Shared Neighborhood Hits	249
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

EDAR_HUMAN
θ value	0.21417 (rank : 301)	NC score	0.056412 (rank : 734)
Query Neighborhood Hits	557	Target Neighborhood Hits	84	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UNE0, Q9UND9	Gene names	EDAR, DL
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (EDA- A1 receptor) (Ectodermal dysplasia receptor) (Downless homolog).

FA47B_HUMAN
θ value	0.21417 (rank : 302)	NC score	0.044106 (rank : 835)
Query Neighborhood Hits	557	Target Neighborhood Hits	431	Shared Neighborhood Hits	60
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

FHL2_MOUSE
θ value	0.21417 (rank : 303)	NC score	0.059118 (rank : 698)
Query Neighborhood Hits	557	Target Neighborhood Hits	539	Shared Neighborhood Hits	56
SwissProt Accessions	O70433, P97448	Gene names	Fhl2
Domain Architecture
Description	Four and a half LIM domains protein 2 (FHL-2) (Skeletal muscle LIM- protein 3) (SLIM 3).

GAS6_HUMAN
θ value	0.21417 (rank : 304)	NC score	0.443751 (rank : 153)
Query Neighborhood Hits	557	Target Neighborhood Hits	348	Shared Neighborhood Hits	216
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

KRA11_HUMAN
θ value	0.21417 (rank : 305)	NC score	0.315612 (rank : 229)
Query Neighborhood Hits	557	Target Neighborhood Hits	155	Shared Neighborhood Hits	101
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

MUCDL_HUMAN
θ value	0.21417 (rank : 306)	NC score	0.090477 (rank : 513)
Query Neighborhood Hits	557	Target Neighborhood Hits	777	Shared Neighborhood Hits	111
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

SSBP4_HUMAN
θ value	0.21417 (rank : 307)	NC score	0.020024 (rank : 902)
Query Neighborhood Hits	557	Target Neighborhood Hits	753	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

YETS2_MOUSE
θ value	0.21417 (rank : 308)	NC score	0.037951 (rank : 853)
Query Neighborhood Hits	557	Target Neighborhood Hits	278	Shared Neighborhood Hits	44
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

ADA19_MOUSE
θ value	0.279714 (rank : 309)	NC score	0.122299 (rank : 409)
Query Neighborhood Hits	557	Target Neighborhood Hits	315	Shared Neighborhood Hits	179
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

BCL9_HUMAN
θ value	0.279714 (rank : 310)	NC score	0.045880 (rank : 831)
Query Neighborhood Hits	557	Target Neighborhood Hits	1008	Shared Neighborhood Hits	101
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

EDAR_MOUSE
θ value	0.279714 (rank : 311)	NC score	0.053449 (rank : 775)
Query Neighborhood Hits	557	Target Neighborhood Hits	66	Shared Neighborhood Hits	27
SwissProt Accessions	Q9R187, Q9DC43	Gene names	Edar, Dl
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (Ectodermal dysplasia receptor) (Downless).

EGFR_MOUSE
θ value	0.279714 (rank : 312)	NC score	0.052408 (rank : 790)
Query Neighborhood Hits	557	Target Neighborhood Hits	927	Shared Neighborhood Hits	108
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

K0319_HUMAN
θ value	0.279714 (rank : 313)	NC score	0.053001 (rank : 780)
Query Neighborhood Hits	557	Target Neighborhood Hits	154	Shared Neighborhood Hits	36
SwissProt Accessions	Q5VV43, Q9UJC8, Q9Y4G7	Gene names	KIAA0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

LYAM1_HUMAN
θ value	0.279714 (rank : 314)	NC score	0.230216 (rank : 299)
Query Neighborhood Hits	557	Target Neighborhood Hits	315	Shared Neighborhood Hits	153
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

MAGD4_HUMAN
θ value	0.279714 (rank : 315)	NC score	0.024522 (rank : 882)
Query Neighborhood Hits	557	Target Neighborhood Hits	338	Shared Neighborhood Hits	57
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

NID1_HUMAN
θ value	0.279714 (rank : 316)	NC score	0.414236 (rank : 173)
Query Neighborhood Hits	557	Target Neighborhood Hits	329	Shared Neighborhood Hits	211
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

PCLO_HUMAN
θ value	0.279714 (rank : 317)	NC score	0.063844 (rank : 653)
Query Neighborhood Hits	557	Target Neighborhood Hits	2046	Shared Neighborhood Hits	166
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SPR1B_MOUSE
θ value	0.279714 (rank : 318)	NC score	0.035810 (rank : 856)
Query Neighborhood Hits	557	Target Neighborhood Hits	395	Shared Neighborhood Hits	53
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

TNR16_MOUSE
θ value	0.279714 (rank : 319)	NC score	0.264570 (rank : 275)
Query Neighborhood Hits	557	Target Neighborhood Hits	178	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR1A_MOUSE
θ value	0.279714 (rank : 320)	NC score	0.107769 (rank : 448)
Query Neighborhood Hits	557	Target Neighborhood Hits	131	Shared Neighborhood Hits	64
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

X3CL1_HUMAN
θ value	0.279714 (rank : 321)	NC score	0.029144 (rank : 869)
Query Neighborhood Hits	557	Target Neighborhood Hits	152	Shared Neighborhood Hits	21
SwissProt Accessions	P78423, O00672	Gene names	CX3CL1, A-152E5.2, FKN, NTT, SCYD1
Domain Architecture
Description	Fractalkine precursor (CX3CL1) (Neurotactin) (CX3C membrane-anchored chemokine) (Small inducible cytokine D1).

ZFHX2_HUMAN
θ value	0.279714 (rank : 322)	NC score	0.014848 (rank : 919)
Query Neighborhood Hits	557	Target Neighborhood Hits	1178	Shared Neighborhood Hits	74
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

ZN230_HUMAN
θ value	0.279714 (rank : 323)	NC score	0.001318 (rank : 975)
Query Neighborhood Hits	557	Target Neighborhood Hits	750	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UIE0, O15322, Q9P1U6	Gene names	ZNF230, FDZF2
Domain Architecture
Description	Zinc finger protein 230 (Zinc finger protein FDZF2).

ITB8_HUMAN
θ value	0.365318 (rank : 324)	NC score	0.396207 (rank : 180)
Query Neighborhood Hits	557	Target Neighborhood Hits	280	Shared Neighborhood Hits	187
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

K1802_MOUSE
θ value	0.365318 (rank : 325)	NC score	0.038110 (rank : 852)
Query Neighborhood Hits	557	Target Neighborhood Hits	1596	Shared Neighborhood Hits	134
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

KR108_HUMAN
θ value	0.365318 (rank : 326)	NC score	0.344207 (rank : 211)
Query Neighborhood Hits	557	Target Neighborhood Hits	226	Shared Neighborhood Hits	136
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

MLL3_MOUSE
θ value	0.365318 (rank : 327)	NC score	0.077962 (rank : 568)
Query Neighborhood Hits	557	Target Neighborhood Hits	1399	Shared Neighborhood Hits	170
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MUC5B_HUMAN
θ value	0.365318 (rank : 328)	NC score	0.311304 (rank : 231)
Query Neighborhood Hits	557	Target Neighborhood Hits	1020	Shared Neighborhood Hits	328
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NFX1_HUMAN
θ value	0.365318 (rank : 329)	NC score	0.282350 (rank : 255)
Query Neighborhood Hits	557	Target Neighborhood Hits	405	Shared Neighborhood Hits	150
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

PSL1_HUMAN
θ value	0.365318 (rank : 330)	NC score	0.031863 (rank : 862)
Query Neighborhood Hits	557	Target Neighborhood Hits	650	Shared Neighborhood Hits	56
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

SAPS1_HUMAN
θ value	0.365318 (rank : 331)	NC score	0.042601 (rank : 838)
Query Neighborhood Hits	557	Target Neighborhood Hits	704	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SEPT9_HUMAN
θ value	0.365318 (rank : 332)	NC score	0.021501 (rank : 893)
Query Neighborhood Hits	557	Target Neighborhood Hits	706	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

TAF9_MOUSE
θ value	0.365318 (rank : 333)	NC score	0.028300 (rank : 875)
Query Neighborhood Hits	557	Target Neighborhood Hits	69	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VI33, Q32P09, Q80XS3, Q9CV61	Gene names	Taf9, Taf2g
Domain Architecture
Description	Transcription initiation factor TFIID subunit 9 (Transcription initiation factor TFIID 31 kDa subunit) (TAFII-31) (TAFII-32) (TAFII32).

TMPS9_HUMAN
θ value	0.365318 (rank : 334)	NC score	0.019581 (rank : 904)
Query Neighborhood Hits	557	Target Neighborhood Hits	276	Shared Neighborhood Hits	35
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

TMPS9_MOUSE
θ value	0.365318 (rank : 335)	NC score	0.019673 (rank : 903)
Query Neighborhood Hits	557	Target Neighborhood Hits	296	Shared Neighborhood Hits	43
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

TNR4_MOUSE
θ value	0.365318 (rank : 336)	NC score	0.271490 (rank : 265)
Query Neighborhood Hits	557	Target Neighborhood Hits	137	Shared Neighborhood Hits	87
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

ADA11_HUMAN
θ value	0.47712 (rank : 337)	NC score	0.144356 (rank : 364)
Query Neighborhood Hits	557	Target Neighborhood Hits	259	Shared Neighborhood Hits	159
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA11_MOUSE
θ value	0.47712 (rank : 338)	NC score	0.144197 (rank : 365)
Query Neighborhood Hits	557	Target Neighborhood Hits	263	Shared Neighborhood Hits	159
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

BMPER_HUMAN
θ value	0.47712 (rank : 339)	NC score	0.162841 (rank : 349)
Query Neighborhood Hits	557	Target Neighborhood Hits	175	Shared Neighborhood Hits	95
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

DOK7_MOUSE
θ value	0.47712 (rank : 340)	NC score	0.024276 (rank : 887)
Query Neighborhood Hits	557	Target Neighborhood Hits	169	Shared Neighborhood Hits	22
SwissProt Accessions	Q18PE0, Q3TCZ6, Q5FW70, Q8C8U7	Gene names	Dok7
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

EP400_MOUSE
θ value	0.47712 (rank : 341)	NC score	0.041703 (rank : 841)
Query Neighborhood Hits	557	Target Neighborhood Hits	592	Shared Neighborhood Hits	93
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

ESM1_HUMAN
θ value	0.47712 (rank : 342)	NC score	0.294085 (rank : 243)
Query Neighborhood Hits	557	Target Neighborhood Hits	110	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

FBLN5_HUMAN
θ value	0.47712 (rank : 343)	NC score	0.392039 (rank : 184)
Query Neighborhood Hits	557	Target Neighborhood Hits	329	Shared Neighborhood Hits	218
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

IQEC3_MOUSE
θ value	0.47712 (rank : 344)	NC score	0.020624 (rank : 899)
Query Neighborhood Hits	557	Target Neighborhood Hits	274	Shared Neighborhood Hits	41
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

KRA24_HUMAN
θ value	0.47712 (rank : 345)	NC score	0.185600 (rank : 330)
Query Neighborhood Hits	557	Target Neighborhood Hits	192	Shared Neighborhood Hits	95
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

MUC2_HUMAN
θ value	0.47712 (rank : 346)	NC score	0.236330 (rank : 292)
Query Neighborhood Hits	557	Target Neighborhood Hits	906	Shared Neighborhood Hits	293
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

ST14_MOUSE
θ value	0.47712 (rank : 347)	NC score	0.080893 (rank : 550)
Query Neighborhood Hits	557	Target Neighborhood Hits	419	Shared Neighborhood Hits	138
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

SUSD1_HUMAN
θ value	0.47712 (rank : 348)	NC score	0.359398 (rank : 204)
Query Neighborhood Hits	557	Target Neighborhood Hits	285	Shared Neighborhood Hits	170
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TAF9_HUMAN
θ value	0.47712 (rank : 349)	NC score	0.029677 (rank : 865)
Query Neighborhood Hits	557	Target Neighborhood Hits	41	Shared Neighborhood Hits	14
SwissProt Accessions	Q16594, Q9BTS1	Gene names	TAF9, TAF2G, TAFII31
Domain Architecture
Description	Transcription initiation factor TFIID subunit 9 (Transcription initiation factor TFIID 31 kDa subunit) (TAFII-31) (TAFII-32) (TAFII32) (STAF31/32).

ELK4_HUMAN
θ value	0.62314 (rank : 350)	NC score	0.010875 (rank : 936)
Query Neighborhood Hits	557	Target Neighborhood Hits	184	Shared Neighborhood Hits	27
SwissProt Accessions	P28324, P28323	Gene names	ELK4, SAP1
Domain Architecture
Description	ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1).

EPHB1_HUMAN
θ value	0.62314 (rank : 351)	NC score	0.052208 (rank : 792)
Query Neighborhood Hits	557	Target Neighborhood Hits	988	Shared Neighborhood Hits	111
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

GP112_HUMAN
θ value	0.62314 (rank : 352)	NC score	0.084251 (rank : 530)
Query Neighborhood Hits	557	Target Neighborhood Hits	441	Shared Neighborhood Hits	75
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

MTR1L_HUMAN
θ value	0.62314 (rank : 353)	NC score	-0.007646 (rank : 992)
Query Neighborhood Hits	557	Target Neighborhood Hits	1180	Shared Neighborhood Hits	44
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

P73L_HUMAN
θ value	0.62314 (rank : 354)	NC score	0.013873 (rank : 927)
Query Neighborhood Hits	557	Target Neighborhood Hits	102	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H3D4, O75080, O75195, O75922, O76078, Q6VEG2, Q6VEG3, Q6VEG4, Q6VFJ1, Q6VFJ2, Q6VFJ3, Q6VH20, Q7LDI3, Q7LDI4, Q7LDI5, Q96KR0, Q9H3D2, Q9H3D3, Q9H3P8, Q9NPH7, Q9P1B4, Q9P1B5, Q9P1B6, Q9P1B7, Q9UBV9, Q9UE10, Q9UP26, Q9UP27, Q9UP28, Q9UP74	Gene names	TP73L, KET, P63, P73H, P73L
Domain Architecture	No domain graphic available
Description	Tumor protein p73-like (p73L) (p63) (Tumor protein 63) (TP63) (p51) (p40) (Keratinocyte transcription factor KET) (Chronic ulcerative stomatitis protein) (CUSP).

PER2_MOUSE
θ value	0.62314 (rank : 355)	NC score	0.020802 (rank : 898)
Query Neighborhood Hits	557	Target Neighborhood Hits	325	Shared Neighborhood Hits	30
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

TR19L_MOUSE
θ value	0.62314 (rank : 356)	NC score	0.103252 (rank : 463)
Query Neighborhood Hits	557	Target Neighborhood Hits	85	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

VASN_MOUSE
θ value	0.62314 (rank : 357)	NC score	0.102682 (rank : 468)
Query Neighborhood Hits	557	Target Neighborhood Hits	426	Shared Neighborhood Hits	117
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

DGKB_HUMAN
θ value	0.813845 (rank : 358)	NC score	0.010724 (rank : 939)
Query Neighborhood Hits	557	Target Neighborhood Hits	238	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y6T7, O75241, Q75MF9, Q75MU7, Q86UI5, Q86UM9, Q9UQ29	Gene names	DGKB, DAGK2, KIAA0718
Domain Architecture
Description	Diacylglycerol kinase beta (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta) (DAG kinase beta) (90 kDa diacylglycerol kinase).

ERBB3_MOUSE
θ value	0.813845 (rank : 359)	NC score	0.055830 (rank : 739)
Query Neighborhood Hits	557	Target Neighborhood Hits	898	Shared Neighborhood Hits	96
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

FBLN3_MOUSE
θ value	0.813845 (rank : 360)	NC score	0.355379 (rank : 207)
Query Neighborhood Hits	557	Target Neighborhood Hits	279	Shared Neighborhood Hits	183
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FHL1_MOUSE
θ value	0.813845 (rank : 361)	NC score	0.038781 (rank : 849)
Query Neighborhood Hits	557	Target Neighborhood Hits	462	Shared Neighborhood Hits	36
SwissProt Accessions	P97447, O55181, Q8K318	Gene names	Fhl1
Domain Architecture
Description	Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle LIM- protein 1) (SLIM 1) (SLIM) (KyoT) (RBP-associated molecule 14-1) (RAM14-1).

KR133_HUMAN
θ value	0.813845 (rank : 362)	NC score	0.069763 (rank : 618)
Query Neighborhood Hits	557	Target Neighborhood Hits	66	Shared Neighborhood Hits	37
SwissProt Accessions	Q3SY46, Q3LI78	Gene names	KRTAP13-3, KAP13.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-3.

SCNNG_HUMAN
θ value	0.813845 (rank : 363)	NC score	0.010832 (rank : 938)
Query Neighborhood Hits	557	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P51170, P78437, Q6PCC2, Q93023, Q93024, Q93025, Q93026, Q93027, Q96TD2	Gene names	SCNN1G
Domain Architecture
Description	Amiloride-sensitive sodium channel gamma-subunit (Epithelial Na+ channel subunit gamma) (Gamma ENaC) (Nonvoltage-gated sodium channel 1 subunit gamma) (SCNEG) (Gamma NaCH).

SRRM2_MOUSE
θ value	0.813845 (rank : 364)	NC score	0.057650 (rank : 721)
Query Neighborhood Hits	557	Target Neighborhood Hits	1470	Shared Neighborhood Hits	136
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

WNK1_HUMAN
θ value	0.813845 (rank : 365)	NC score	0.013975 (rank : 925)
Query Neighborhood Hits	557	Target Neighborhood Hits	1158	Shared Neighborhood Hits	114
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

ZN221_HUMAN
θ value	0.813845 (rank : 366)	NC score	0.008360 (rank : 952)
Query Neighborhood Hits	557	Target Neighborhood Hits	784	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UK13, Q9P1U8	Gene names	ZNF221
Domain Architecture
Description	Zinc finger protein 221.

ZN711_HUMAN
θ value	0.813845 (rank : 367)	NC score	-0.002579 (rank : 981)
Query Neighborhood Hits	557	Target Neighborhood Hits	751	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y462, Q6NX42, Q9Y4J6	Gene names	ZNF711, CMPX1, ZNF6
Domain Architecture
Description	Zinc finger protein 711 (Zinc finger protein 6).

EPHA1_HUMAN
θ value	1.06291 (rank : 368)	NC score	0.063717 (rank : 654)
Query Neighborhood Hits	557	Target Neighborhood Hits	997	Shared Neighborhood Hits	130
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

ESM1_MOUSE
θ value	1.06291 (rank : 369)	NC score	0.254317 (rank : 280)
Query Neighborhood Hits	557	Target Neighborhood Hits	107	Shared Neighborhood Hits	62
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

HRBL_MOUSE
θ value	1.06291 (rank : 370)	NC score	0.018070 (rank : 910)
Query Neighborhood Hits	557	Target Neighborhood Hits	269	Shared Neighborhood Hits	28
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

HSF1_MOUSE
θ value	1.06291 (rank : 371)	NC score	0.021192 (rank : 896)
Query Neighborhood Hits	557	Target Neighborhood Hits	267	Shared Neighborhood Hits	25
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

K1333_HUMAN
θ value	1.06291 (rank : 372)	NC score	0.016141 (rank : 915)
Query Neighborhood Hits	557	Target Neighborhood Hits	50	Shared Neighborhood Hits	9
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

MAGL2_HUMAN
θ value	1.06291 (rank : 373)	NC score	0.013157 (rank : 930)
Query Neighborhood Hits	557	Target Neighborhood Hits	69	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UJ55	Gene names	MAGEL2, NDNL1
Domain Architecture
Description	MAGE-like protein 2 (Necdin-like protein 1) (Protein nM15).

MFGM_MOUSE
θ value	1.06291 (rank : 374)	NC score	0.293379 (rank : 244)
Query Neighborhood Hits	557	Target Neighborhood Hits	233	Shared Neighborhood Hits	154
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

MINT_MOUSE
θ value	1.06291 (rank : 375)	NC score	0.032932 (rank : 859)
Query Neighborhood Hits	557	Target Neighborhood Hits	1514	Shared Neighborhood Hits	116
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NCOA6_HUMAN
θ value	1.06291 (rank : 376)	NC score	0.058724 (rank : 704)
Query Neighborhood Hits	557	Target Neighborhood Hits	1202	Shared Neighborhood Hits	126
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

OBF1_HUMAN
θ value	1.06291 (rank : 377)	NC score	0.023428 (rank : 889)
Query Neighborhood Hits	557	Target Neighborhood Hits	203	Shared Neighborhood Hits	26
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

PROZ_HUMAN
θ value	1.06291 (rank : 378)	NC score	0.301676 (rank : 238)
Query Neighborhood Hits	557	Target Neighborhood Hits	422	Shared Neighborhood Hits	189
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

RGS3_HUMAN
θ value	1.06291 (rank : 379)	NC score	0.027089 (rank : 877)
Query Neighborhood Hits	557	Target Neighborhood Hits	1375	Shared Neighborhood Hits	103
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

ZN234_HUMAN
θ value	1.06291 (rank : 380)	NC score	0.001544 (rank : 974)
Query Neighborhood Hits	557	Target Neighborhood Hits	785	Shared Neighborhood Hits	47
SwissProt Accessions	Q14588, Q96IR4, Q9NS45, Q9NYT7	Gene names	ZNF234, ZNF269
Domain Architecture	No domain graphic available
Description	Zinc finger protein 234 (Zinc finger protein HZF4).

CD248_MOUSE
θ value	1.38821 (rank : 381)	NC score	0.327435 (rank : 219)
Query Neighborhood Hits	557	Target Neighborhood Hits	578	Shared Neighborhood Hits	207
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CORIN_HUMAN
θ value	1.38821 (rank : 382)	NC score	0.127776 (rank : 399)
Query Neighborhood Hits	557	Target Neighborhood Hits	453	Shared Neighborhood Hits	159
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

DAF1_MOUSE
θ value	1.38821 (rank : 383)	NC score	0.032912 (rank : 860)
Query Neighborhood Hits	557	Target Neighborhood Hits	204	Shared Neighborhood Hits	38
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

EMR1_HUMAN
θ value	1.38821 (rank : 384)	NC score	0.359399 (rank : 203)
Query Neighborhood Hits	557	Target Neighborhood Hits	382	Shared Neighborhood Hits	204
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EP400_HUMAN
θ value	1.38821 (rank : 385)	NC score	0.042810 (rank : 837)
Query Neighborhood Hits	557	Target Neighborhood Hits	556	Shared Neighborhood Hits	107
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

FA47A_HUMAN
θ value	1.38821 (rank : 386)	NC score	0.045240 (rank : 832)
Query Neighborhood Hits	557	Target Neighborhood Hits	451	Shared Neighborhood Hits	53
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

PAPOG_HUMAN
θ value	1.38821 (rank : 387)	NC score	0.011157 (rank : 933)
Query Neighborhood Hits	557	Target Neighborhood Hits	44	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BWT3, Q969N1, Q9H8L2, Q9HAD0	Gene names	PAPOLG, PAP2, PAPG
Domain Architecture
Description	Poly(A) polymerase gamma (EC 2.7.7.19) (PAP gamma) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3' adenylating enzyme) (Neo- poly(A) polymerase) (Neo-PAP).

RFIP3_HUMAN
θ value	1.38821 (rank : 388)	NC score	0.015682 (rank : 917)
Query Neighborhood Hits	557	Target Neighborhood Hits	1055	Shared Neighborhood Hits	48
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

RSPO3_HUMAN
θ value	1.38821 (rank : 389)	NC score	0.114720 (rank : 428)
Query Neighborhood Hits	557	Target Neighborhood Hits	128	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

SPEG_MOUSE
θ value	1.38821 (rank : 390)	NC score	0.022947 (rank : 890)
Query Neighborhood Hits	557	Target Neighborhood Hits	1959	Shared Neighborhood Hits	150
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SRCH_HUMAN
θ value	1.38821 (rank : 391)	NC score	0.070592 (rank : 612)
Query Neighborhood Hits	557	Target Neighborhood Hits	225	Shared Neighborhood Hits	37
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

TARA_HUMAN
θ value	1.38821 (rank : 392)	NC score	0.039781 (rank : 845)
Query Neighborhood Hits	557	Target Neighborhood Hits	1626	Shared Neighborhood Hits	114
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TNR26_MOUSE
θ value	1.38821 (rank : 393)	NC score	0.133735 (rank : 388)
Query Neighborhood Hits	557	Target Neighborhood Hits	106	Shared Neighborhood Hits	71
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR7_HUMAN
θ value	1.38821 (rank : 394)	NC score	0.192990 (rank : 324)
Query Neighborhood Hits	557	Target Neighborhood Hits	120	Shared Neighborhood Hits	76
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

ZN699_HUMAN
θ value	1.38821 (rank : 395)	NC score	-0.003091 (rank : 982)
Query Neighborhood Hits	557	Target Neighborhood Hits	773	Shared Neighborhood Hits	39
SwissProt Accessions	Q32M78, Q8N9A1	Gene names	ZNF699
Domain Architecture	No domain graphic available
Description	Zinc finger protein 699 (Hangover homolog).

ADA23_MOUSE
θ value	1.81305 (rank : 396)	NC score	0.128346 (rank : 396)
Query Neighborhood Hits	557	Target Neighborhood Hits	245	Shared Neighborhood Hits	153
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ATX7_MOUSE
θ value	1.81305 (rank : 397)	NC score	0.028326 (rank : 873)
Query Neighborhood Hits	557	Target Neighborhood Hits	328	Shared Neighborhood Hits	48
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

BAZ2A_MOUSE
θ value	1.81305 (rank : 398)	NC score	0.025943 (rank : 878)
Query Neighborhood Hits	557	Target Neighborhood Hits	744	Shared Neighborhood Hits	75
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

CAMKV_HUMAN
θ value	1.81305 (rank : 399)	NC score	0.006724 (rank : 957)
Query Neighborhood Hits	557	Target Neighborhood Hits	1084	Shared Neighborhood Hits	77
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

DAB2_HUMAN
θ value	1.81305 (rank : 400)	NC score	0.016358 (rank : 914)
Query Neighborhood Hits	557	Target Neighborhood Hits	197	Shared Neighborhood Hits	29
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

DUET_HUMAN
θ value	1.81305 (rank : 401)	NC score	0.008127 (rank : 954)
Query Neighborhood Hits	557	Target Neighborhood Hits	1220	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

EPHB3_HUMAN
θ value	1.81305 (rank : 402)	NC score	0.054115 (rank : 763)
Query Neighborhood Hits	557	Target Neighborhood Hits	996	Shared Neighborhood Hits	93
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

ERBB2_HUMAN
θ value	1.81305 (rank : 403)	NC score	0.052183 (rank : 795)
Query Neighborhood Hits	557	Target Neighborhood Hits	1073	Shared Neighborhood Hits	108
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

FHL1_HUMAN
θ value	1.81305 (rank : 404)	NC score	0.036837 (rank : 854)
Query Neighborhood Hits	557	Target Neighborhood Hits	436	Shared Neighborhood Hits	34
SwissProt Accessions	Q13642, O95212, Q13230, Q13645, Q5M7Y6, Q9NZ40, Q9UKZ8, Q9Y630	Gene names	FHL1, SLIM1
Domain Architecture
Description	Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle LIM- protein 1) (SLIM 1) (SLIM).

KR10A_HUMAN
θ value	1.81305 (rank : 405)	NC score	0.283035 (rank : 254)
Query Neighborhood Hits	557	Target Neighborhood Hits	232	Shared Neighborhood Hits	138
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

NELFA_HUMAN
θ value	1.81305 (rank : 406)	NC score	0.067007 (rank : 630)
Query Neighborhood Hits	557	Target Neighborhood Hits	161	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H3P2, O95392	Gene names	WHSC2, NELFA
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein).

NFH_MOUSE
θ value	1.81305 (rank : 407)	NC score	0.027288 (rank : 876)
Query Neighborhood Hits	557	Target Neighborhood Hits	2247	Shared Neighborhood Hits	124
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NUPL_HUMAN
θ value	1.81305 (rank : 408)	NC score	0.013695 (rank : 928)
Query Neighborhood Hits	557	Target Neighborhood Hits	68	Shared Neighborhood Hits	7
SwissProt Accessions	P52594, Q15277, Q4VAS0, Q4VAS1, Q4VAS3, Q53QT8, Q53R11	Gene names	HRB, RAB, RIP
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein) (Rev- interacting protein) (Rev/Rex activation domain-binding protein).

RUSC2_MOUSE
θ value	1.81305 (rank : 409)	NC score	0.020181 (rank : 901)
Query Neighborhood Hits	557	Target Neighborhood Hits	305	Shared Neighborhood Hits	43
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SON_MOUSE
θ value	1.81305 (rank : 410)	NC score	0.071769 (rank : 604)
Query Neighborhood Hits	557	Target Neighborhood Hits	957	Shared Neighborhood Hits	111
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SPR1A_MOUSE
θ value	1.81305 (rank : 411)	NC score	0.035746 (rank : 857)
Query Neighborhood Hits	557	Target Neighborhood Hits	343	Shared Neighborhood Hits	45
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

TAU_MOUSE
θ value	1.81305 (rank : 412)	NC score	0.041546 (rank : 842)
Query Neighborhood Hits	557	Target Neighborhood Hits	502	Shared Neighborhood Hits	71
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TNR6_MOUSE
θ value	1.81305 (rank : 413)	NC score	0.129484 (rank : 395)
Query Neighborhood Hits	557	Target Neighborhood Hits	99	Shared Neighborhood Hits	63
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR9_MOUSE
θ value	1.81305 (rank : 414)	NC score	0.197237 (rank : 320)
Query Neighborhood Hits	557	Target Neighborhood Hits	137	Shared Neighborhood Hits	80
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TP53B_MOUSE
θ value	1.81305 (rank : 415)	NC score	0.029225 (rank : 867)
Query Neighborhood Hits	557	Target Neighborhood Hits	644	Shared Neighborhood Hits	65
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TSP2_MOUSE
θ value	1.81305 (rank : 416)	NC score	0.268339 (rank : 268)
Query Neighborhood Hits	557	Target Neighborhood Hits	352	Shared Neighborhood Hits	191
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

ADA19_HUMAN
θ value	2.36792 (rank : 417)	NC score	0.115605 (rank : 425)
Query Neighborhood Hits	557	Target Neighborhood Hits	381	Shared Neighborhood Hits	171
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ADAM7_HUMAN
θ value	2.36792 (rank : 418)	NC score	0.110693 (rank : 441)
Query Neighborhood Hits	557	Target Neighborhood Hits	221	Shared Neighborhood Hits	138
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ADM1A_MOUSE
θ value	2.36792 (rank : 419)	NC score	0.095345 (rank : 499)
Query Neighborhood Hits	557	Target Neighborhood Hits	230	Shared Neighborhood Hits	138
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ATX2_MOUSE
θ value	2.36792 (rank : 420)	NC score	0.040006 (rank : 844)
Query Neighborhood Hits	557	Target Neighborhood Hits	445	Shared Neighborhood Hits	71
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

EPHA4_HUMAN
θ value	2.36792 (rank : 421)	NC score	0.050329 (rank : 819)
Query Neighborhood Hits	557	Target Neighborhood Hits	975	Shared Neighborhood Hits	86
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

EPHA4_MOUSE
θ value	2.36792 (rank : 422)	NC score	0.051046 (rank : 807)
Query Neighborhood Hits	557	Target Neighborhood Hits	982	Shared Neighborhood Hits	92
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

EPHA6_HUMAN
θ value	2.36792 (rank : 423)	NC score	0.055359 (rank : 745)
Query Neighborhood Hits	557	Target Neighborhood Hits	959	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

ERBB2_MOUSE
θ value	2.36792 (rank : 424)	NC score	0.048706 (rank : 826)
Query Neighborhood Hits	557	Target Neighborhood Hits	918	Shared Neighborhood Hits	92
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

GRN_MOUSE
θ value	2.36792 (rank : 425)	NC score	0.324225 (rank : 222)
Query Neighborhood Hits	557	Target Neighborhood Hits	248	Shared Neighborhood Hits	158
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

HABP2_HUMAN
θ value	2.36792 (rank : 426)	NC score	0.235065 (rank : 294)
Query Neighborhood Hits	557	Target Neighborhood Hits	431	Shared Neighborhood Hits	202
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HDAC6_MOUSE
θ value	2.36792 (rank : 427)	NC score	0.007981 (rank : 955)
Query Neighborhood Hits	557	Target Neighborhood Hits	88	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z2V5	Gene names	Hdac6
Domain Architecture
Description	Histone deacetylase 6 (HD6) (Histone deacetylase mHDA2).

MUCEN_MOUSE
θ value	2.36792 (rank : 428)	NC score	0.028375 (rank : 872)
Query Neighborhood Hits	557	Target Neighborhood Hits	65	Shared Neighborhood Hits	15
SwissProt Accessions	Q9R0H2, Q78KL2, Q9DCN9, Q9ULC1, Q9Z2I1	Gene names	Emcn, Muc14
Domain Architecture	No domain graphic available
Description	Endomucin precursor (Endomucin-1/2).

P2RX2_HUMAN
θ value	2.36792 (rank : 429)	NC score	0.010877 (rank : 935)
Query Neighborhood Hits	557	Target Neighborhood Hits	110	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UBL9, Q6V9R6, Q9NR37, Q9NR38, Q9UHD5, Q9UHD6, Q9UHD7, Q9Y637, Q9Y638	Gene names	P2RX2, P2X2
Domain Architecture
Description	P2X purinoceptor 2 (ATP receptor) (P2X2) (Purinergic receptor).

RSPO2_HUMAN
θ value	2.36792 (rank : 430)	NC score	0.100279 (rank : 480)
Query Neighborhood Hits	557	Target Neighborhood Hits	90	Shared Neighborhood Hits	42
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

SCNNB_HUMAN
θ value	2.36792 (rank : 431)	NC score	0.008847 (rank : 948)
Query Neighborhood Hits	557	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	P51168, O60891, Q96KG2, Q9UJ32, Q9UMU5	Gene names	SCNN1B
Domain Architecture
Description	Amiloride-sensitive sodium channel subunit beta (Epithelial Na+ channel subunit beta) (Beta ENaC) (Nonvoltage-gated sodium channel 1 subunit beta) (SCNEB) (Beta NaCH) (ENaCB).

SFRS8_HUMAN
θ value	2.36792 (rank : 432)	NC score	0.038195 (rank : 850)
Query Neighborhood Hits	557	Target Neighborhood Hits	166	Shared Neighborhood Hits	27
SwissProt Accessions	Q12872	Gene names	SFRS8, SWAP
Domain Architecture
Description	Splicing factor, arginine/serine-rich 8 (Suppressor of white apricot protein homolog).

TNR22_MOUSE
θ value	2.36792 (rank : 433)	NC score	0.197168 (rank : 321)
Query Neighborhood Hits	557	Target Neighborhood Hits	97	Shared Neighborhood Hits	62
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TSP2_HUMAN
θ value	2.36792 (rank : 434)	NC score	0.262651 (rank : 277)
Query Neighborhood Hits	557	Target Neighborhood Hits	359	Shared Neighborhood Hits	189
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

VEGFC_HUMAN
θ value	2.36792 (rank : 435)	NC score	0.134318 (rank : 384)
Query Neighborhood Hits	557	Target Neighborhood Hits	128	Shared Neighborhood Hits	83
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

ZFX_HUMAN
θ value	2.36792 (rank : 436)	NC score	-0.003173 (rank : 986)
Query Neighborhood Hits	557	Target Neighborhood Hits	751	Shared Neighborhood Hits	27
SwissProt Accessions	P17010, O43668, Q8WYJ8	Gene names	ZFX
Domain Architecture
Description	Zinc finger X-chromosomal protein.

ZFX_MOUSE
θ value	2.36792 (rank : 437)	NC score	-0.003133 (rank : 985)
Query Neighborhood Hits	557	Target Neighborhood Hits	748	Shared Neighborhood Hits	27
SwissProt Accessions	P17012, P17011	Gene names	Zfx
Domain Architecture
Description	Zinc finger X-chromosomal protein.

ADA21_MOUSE
θ value	3.0926 (rank : 438)	NC score	0.083364 (rank : 535)
Query Neighborhood Hits	557	Target Neighborhood Hits	172	Shared Neighborhood Hits	103
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

ADA23_HUMAN
θ value	3.0926 (rank : 439)	NC score	0.131408 (rank : 394)
Query Neighborhood Hits	557	Target Neighborhood Hits	235	Shared Neighborhood Hits	147
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA33_HUMAN
θ value	3.0926 (rank : 440)	NC score	0.115761 (rank : 424)
Query Neighborhood Hits	557	Target Neighborhood Hits	264	Shared Neighborhood Hits	146
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

DCC_MOUSE
θ value	3.0926 (rank : 441)	NC score	0.058537 (rank : 708)
Query Neighborhood Hits	557	Target Neighborhood Hits	896	Shared Neighborhood Hits	103
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

EGF_MOUSE
θ value	3.0926 (rank : 442)	NC score	0.391993 (rank : 185)
Query Neighborhood Hits	557	Target Neighborhood Hits	358	Shared Neighborhood Hits	223
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

EPN3_MOUSE
θ value	3.0926 (rank : 443)	NC score	0.018222 (rank : 909)
Query Neighborhood Hits	557	Target Neighborhood Hits	312	Shared Neighborhood Hits	44
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

FINC_HUMAN
θ value	3.0926 (rank : 444)	NC score	0.097257 (rank : 491)
Query Neighborhood Hits	557	Target Neighborhood Hits	302	Shared Neighborhood Hits	77
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

GCP6_HUMAN
θ value	3.0926 (rank : 445)	NC score	0.008954 (rank : 945)
Query Neighborhood Hits	557	Target Neighborhood Hits	295	Shared Neighborhood Hits	13
SwissProt Accessions	Q96RT7, Q5JZ80, Q6PJ40, Q86YE9, Q9BY91, Q9UGX3, Q9UGX4	Gene names	TUBGCP6, GCP6, KIAA1669
Domain Architecture
Description	Gamma-tubulin complex component 6 (GCP-6).

GON4L_MOUSE
θ value	3.0926 (rank : 446)	NC score	0.021237 (rank : 895)
Query Neighborhood Hits	557	Target Neighborhood Hits	455	Shared Neighborhood Hits	51
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

HGFA_MOUSE
θ value	3.0926 (rank : 447)	NC score	0.160168 (rank : 352)
Query Neighborhood Hits	557	Target Neighborhood Hits	419	Shared Neighborhood Hits	177
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

JIP3_HUMAN
θ value	3.0926 (rank : 448)	NC score	0.012800 (rank : 931)
Query Neighborhood Hits	557	Target Neighborhood Hits	1039	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

K1219_MOUSE
θ value	3.0926 (rank : 449)	NC score	0.014129 (rank : 923)
Query Neighborhood Hits	557	Target Neighborhood Hits	67	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BQZ4, Q80TH5, Q8BQN1	Gene names	Kiaa1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

KCNB2_HUMAN
θ value	3.0926 (rank : 450)	NC score	-0.000474 (rank : 976)
Query Neighborhood Hits	557	Target Neighborhood Hits	212	Shared Neighborhood Hits	11
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

LMO6_HUMAN
θ value	3.0926 (rank : 451)	NC score	0.028315 (rank : 874)
Query Neighborhood Hits	557	Target Neighborhood Hits	337	Shared Neighborhood Hits	30
SwissProt Accessions	O43900, O76007	Gene names	LMO6
Domain Architecture
Description	LIM domain only protein 6 (Triple LIM domain protein 6).

MLL2_HUMAN
θ value	3.0926 (rank : 452)	NC score	0.082111 (rank : 543)
Query Neighborhood Hits	557	Target Neighborhood Hits	1788	Shared Neighborhood Hits	189
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MUC1_MOUSE
θ value	3.0926 (rank : 453)	NC score	0.083309 (rank : 536)
Query Neighborhood Hits	557	Target Neighborhood Hits	388	Shared Neighborhood Hits	68
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

NIPA_MOUSE
θ value	3.0926 (rank : 454)	NC score	0.014520 (rank : 922)
Query Neighborhood Hits	557	Target Neighborhood Hits	50	Shared Neighborhood Hits	11
SwissProt Accessions	Q80YV2, Q3TJE6, Q80Z11, Q8BTW5, Q8CI56, Q8R3U7	Gene names	Zc3hc1, Nipa
Domain Architecture	No domain graphic available
Description	Nuclear-interacting partner of ALK (Nuclear-interacting partner of anaplastic lymphoma kinase) (mNIPA) (Zinc finger C3HC-type protein 1).

PAX6_HUMAN
θ value	3.0926 (rank : 455)	NC score	-0.003093 (rank : 983)
Query Neighborhood Hits	557	Target Neighborhood Hits	383	Shared Neighborhood Hits	9
SwissProt Accessions	P26367, Q6N006, Q99413	Gene names	PAX6, AN2
Domain Architecture
Description	Paired box protein Pax-6 (Oculorhombin) (Aniridia type II protein).

PAX6_MOUSE
θ value	3.0926 (rank : 456)	NC score	-0.003093 (rank : 984)
Query Neighborhood Hits	557	Target Neighborhood Hits	383	Shared Neighborhood Hits	9
SwissProt Accessions	P63015, P32117, P70601, Q62222, Q64037, Q8CEI5, Q8VDB5, Q921Q8	Gene names	Pax6, Pax-6, Sey
Domain Architecture	No domain graphic available
Description	Paired box protein Pax-6 (Oculorhombin).

RGS3_MOUSE
θ value	3.0926 (rank : 457)	NC score	0.047418 (rank : 828)
Query Neighborhood Hits	557	Target Neighborhood Hits	1621	Shared Neighborhood Hits	133
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SC24C_HUMAN
θ value	3.0926 (rank : 458)	NC score	0.036354 (rank : 855)
Query Neighborhood Hits	557	Target Neighborhood Hits	662	Shared Neighborhood Hits	70
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

TM108_HUMAN
θ value	3.0926 (rank : 459)	NC score	0.066468 (rank : 636)
Query Neighborhood Hits	557	Target Neighborhood Hits	166	Shared Neighborhood Hits	55
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

USH1C_MOUSE
θ value	3.0926 (rank : 460)	NC score	0.010874 (rank : 937)
Query Neighborhood Hits	557	Target Neighborhood Hits	557	Shared Neighborhood Hits	34
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

ZN467_MOUSE
θ value	3.0926 (rank : 461)	NC score	-0.000794 (rank : 978)
Query Neighborhood Hits	557	Target Neighborhood Hits	794	Shared Neighborhood Hits	45
SwissProt Accessions	Q8JZL0, Q9JJ98	Gene names	Znf467, Ezi, Zfp467
Domain Architecture	No domain graphic available
Description	Zinc finger protein 467 (Endothelial cell-derived zinc finger protein) (EZI).

ZNF93_HUMAN
θ value	3.0926 (rank : 462)	NC score	-0.004193 (rank : 988)
Query Neighborhood Hits	557	Target Neighborhood Hits	776	Shared Neighborhood Hits	37
SwissProt Accessions	P35789, Q8N8Q4, Q9H9X5, Q9Y2N8	Gene names	ZNF93, ZNF505
Domain Architecture	No domain graphic available
Description	Zinc finger protein 93 (Zinc finger protein 505) (Zinc finger protein HTF34).

AMPH_HUMAN
θ value	4.03905 (rank : 463)	NC score	0.029520 (rank : 866)
Query Neighborhood Hits	557	Target Neighborhood Hits	455	Shared Neighborhood Hits	55
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

ATS12_MOUSE
θ value	4.03905 (rank : 464)	NC score	0.024493 (rank : 885)
Query Neighborhood Hits	557	Target Neighborhood Hits	220	Shared Neighborhood Hits	54
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATX7_HUMAN
θ value	4.03905 (rank : 465)	NC score	0.032044 (rank : 861)
Query Neighborhood Hits	557	Target Neighborhood Hits	351	Shared Neighborhood Hits	50
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

CO6_HUMAN
θ value	4.03905 (rank : 466)	NC score	0.155361 (rank : 357)
Query Neighborhood Hits	557	Target Neighborhood Hits	331	Shared Neighborhood Hits	131
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

EDD1_HUMAN
θ value	4.03905 (rank : 467)	NC score	0.004702 (rank : 963)
Query Neighborhood Hits	557	Target Neighborhood Hits	170	Shared Neighborhood Hits	12
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

EGFL7_MOUSE
θ value	4.03905 (rank : 468)	NC score	0.418646 (rank : 170)
Query Neighborhood Hits	557	Target Neighborhood Hits	287	Shared Neighborhood Hits	195
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

HNF1A_HUMAN
θ value	4.03905 (rank : 469)	NC score	0.020362 (rank : 900)
Query Neighborhood Hits	557	Target Neighborhood Hits	193	Shared Neighborhood Hits	31
SwissProt Accessions	P20823, Q99861	Gene names	TCF1, HNF1A
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1) (Transcription factor 1) (TCF-1).

I12R1_HUMAN
θ value	4.03905 (rank : 470)	NC score	0.018801 (rank : 907)
Query Neighborhood Hits	557	Target Neighborhood Hits	78	Shared Neighborhood Hits	25
SwissProt Accessions	P42701	Gene names	IL12RB1, IL12R, IL12RB
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (IL- 12RB1) (CD212 antigen).

IL12B_MOUSE
θ value	4.03905 (rank : 471)	NC score	0.019401 (rank : 906)
Query Neighborhood Hits	557	Target Neighborhood Hits	43	Shared Neighborhood Hits	8
SwissProt Accessions	P43432, Q9QUM1	Gene names	Il12b
Domain Architecture
Description	Interleukin-12 beta chain precursor (IL-12B) (IL-12 p40) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40).

K1683_HUMAN
θ value	4.03905 (rank : 472)	NC score	0.039534 (rank : 848)
Query Neighborhood Hits	557	Target Neighborhood Hits	240	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

K1802_HUMAN
θ value	4.03905 (rank : 473)	NC score	0.047827 (rank : 827)
Query Neighborhood Hits	557	Target Neighborhood Hits	1378	Shared Neighborhood Hits	143
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LR37A_HUMAN
θ value	4.03905 (rank : 474)	NC score	0.055198 (rank : 749)
Query Neighborhood Hits	557	Target Neighborhood Hits	720	Shared Neighborhood Hits	95
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

PKP4_HUMAN
θ value	4.03905 (rank : 475)	NC score	0.005518 (rank : 962)
Query Neighborhood Hits	557	Target Neighborhood Hits	107	Shared Neighborhood Hits	15
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

RERE_MOUSE
θ value	4.03905 (rank : 476)	NC score	0.067296 (rank : 629)
Query Neighborhood Hits	557	Target Neighborhood Hits	785	Shared Neighborhood Hits	123
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

REXO1_HUMAN
θ value	4.03905 (rank : 477)	NC score	0.019578 (rank : 905)
Query Neighborhood Hits	557	Target Neighborhood Hits	242	Shared Neighborhood Hits	33
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

RSPO2_MOUSE
θ value	4.03905 (rank : 478)	NC score	0.098753 (rank : 488)
Query Neighborhood Hits	557	Target Neighborhood Hits	88	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

RSPO3_MOUSE
θ value	4.03905 (rank : 479)	NC score	0.103122 (rank : 465)
Query Neighborhood Hits	557	Target Neighborhood Hits	120	Shared Neighborhood Hits	66
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

SETD2_HUMAN
θ value	4.03905 (rank : 480)	NC score	0.024855 (rank : 881)
Query Neighborhood Hits	557	Target Neighborhood Hits	412	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SOX13_HUMAN
θ value	4.03905 (rank : 481)	NC score	0.014053 (rank : 924)
Query Neighborhood Hits	557	Target Neighborhood Hits	464	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

SOX15_HUMAN
θ value	4.03905 (rank : 482)	NC score	0.001895 (rank : 973)
Query Neighborhood Hits	557	Target Neighborhood Hits	134	Shared Neighborhood Hits	5
SwissProt Accessions	O60248, P35717, Q9Y6W7	Gene names	SOX15, SOX12, SOX20, SOX26, SOX27
Domain Architecture
Description	SOX-15 protein (SOX-20 protein) (SOX-12 protein).

TCF17_HUMAN
θ value	4.03905 (rank : 483)	NC score	-0.000776 (rank : 977)
Query Neighborhood Hits	557	Target Neighborhood Hits	797	Shared Neighborhood Hits	47
SwissProt Accessions	O60765, Q9UNJ8	Gene names	ZNF354A, EZNF, HKL1, TCF17
Domain Architecture
Description	Zinc finger protein 354A (Transcription factor 17) (Zinc finger protein eZNF).

TNR8_HUMAN
θ value	4.03905 (rank : 484)	NC score	0.143333 (rank : 369)
Query Neighborhood Hits	557	Target Neighborhood Hits	198	Shared Neighborhood Hits	95
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TR11B_HUMAN
θ value	4.03905 (rank : 485)	NC score	0.081173 (rank : 548)
Query Neighborhood Hits	557	Target Neighborhood Hits	92	Shared Neighborhood Hits	51
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

BTBDC_HUMAN
θ value	5.27518 (rank : 486)	NC score	0.018591 (rank : 908)
Query Neighborhood Hits	557	Target Neighborhood Hits	248	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

CABIN_HUMAN
θ value	5.27518 (rank : 487)	NC score	0.046578 (rank : 830)
Query Neighborhood Hits	557	Target Neighborhood Hits	490	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CD45_HUMAN
θ value	5.27518 (rank : 488)	NC score	0.012198 (rank : 932)
Query Neighborhood Hits	557	Target Neighborhood Hits	243	Shared Neighborhood Hits	36
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

ELTD1_MOUSE
θ value	5.27518 (rank : 489)	NC score	0.283969 (rank : 252)
Query Neighborhood Hits	557	Target Neighborhood Hits	288	Shared Neighborhood Hits	159
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

EPHB3_MOUSE
θ value	5.27518 (rank : 490)	NC score	0.049563 (rank : 823)
Query Neighborhood Hits	557	Target Neighborhood Hits	996	Shared Neighborhood Hits	84
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

FINC_MOUSE
θ value	5.27518 (rank : 491)	NC score	0.096979 (rank : 493)
Query Neighborhood Hits	557	Target Neighborhood Hits	309	Shared Neighborhood Hits	82
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

FOXH1_HUMAN
θ value	5.27518 (rank : 492)	NC score	0.003485 (rank : 970)
Query Neighborhood Hits	557	Target Neighborhood Hits	258	Shared Neighborhood Hits	24
SwissProt Accessions	O75593	Gene names	FOXH1, FAST1, FAST2
Domain Architecture
Description	Forkhead box protein H1 (Forkhead activin signal transducer 1) (Fast- 1) (hFAST-1) (Forkhead activin signal transducer 2) (Fast-2).

FOXN1_HUMAN
θ value	5.27518 (rank : 493)	NC score	0.003500 (rank : 969)
Query Neighborhood Hits	557	Target Neighborhood Hits	377	Shared Neighborhood Hits	27
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

HKR3_HUMAN
θ value	5.27518 (rank : 494)	NC score	-0.005308 (rank : 989)
Query Neighborhood Hits	557	Target Neighborhood Hits	839	Shared Neighborhood Hits	34
SwissProt Accessions	P10074	Gene names	HKR3
Domain Architecture
Description	Krueppel-related zinc finger protein 3 (Protein HKR3).

KLF10_HUMAN
θ value	5.27518 (rank : 495)	NC score	-0.006289 (rank : 991)
Query Neighborhood Hits	557	Target Neighborhood Hits	744	Shared Neighborhood Hits	36
SwissProt Accessions	Q13118	Gene names	KLF10, TIEG, TIEG1
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 10 (Transforming growth factor-beta-inducible early growth response protein 1) (TGFB-inducible early growth response protein 1) (TIEG-1) (EGR-alpha).

KR103_HUMAN
θ value	5.27518 (rank : 496)	NC score	0.269894 (rank : 267)
Query Neighborhood Hits	557	Target Neighborhood Hits	212	Shared Neighborhood Hits	121
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

KRA15_HUMAN
θ value	5.27518 (rank : 497)	NC score	0.243128 (rank : 289)
Query Neighborhood Hits	557	Target Neighborhood Hits	126	Shared Neighborhood Hits	82
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

MAP4_MOUSE
θ value	5.27518 (rank : 498)	NC score	0.058111 (rank : 712)
Query Neighborhood Hits	557	Target Neighborhood Hits	409	Shared Neighborhood Hits	79
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

TCF19_HUMAN
θ value	5.27518 (rank : 499)	NC score	0.017601 (rank : 911)
Query Neighborhood Hits	557	Target Neighborhood Hits	124	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y242, Q13176, Q15967, Q5SQ89, Q5STD6, Q5STF5, Q9BUM2, Q9UBH7	Gene names	TCF19, SC1
Domain Architecture
Description	Transcription factor 19 (Transcription factor SC1).

TENN_MOUSE
θ value	5.27518 (rank : 500)	NC score	0.322539 (rank : 225)
Query Neighborhood Hits	557	Target Neighborhood Hits	484	Shared Neighborhood Hits	240
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TR10C_HUMAN
θ value	5.27518 (rank : 501)	NC score	0.073410 (rank : 596)
Query Neighborhood Hits	557	Target Neighborhood Hits	105	Shared Neighborhood Hits	59
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

TRAF3_MOUSE
θ value	5.27518 (rank : 502)	NC score	0.003133 (rank : 971)
Query Neighborhood Hits	557	Target Neighborhood Hits	476	Shared Neighborhood Hits	12
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

TTLL5_MOUSE
θ value	5.27518 (rank : 503)	NC score	0.006060 (rank : 958)
Query Neighborhood Hits	557	Target Neighborhood Hits	150	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CHB8	Gene names	Ttll5, Kiaa0998
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5.

VP13B_HUMAN
θ value	5.27518 (rank : 504)	NC score	0.008590 (rank : 951)
Query Neighborhood Hits	557	Target Neighborhood Hits	78	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z7G8, Q709C6, Q709C7, Q7Z7G4, Q7Z7G5, Q7Z7G6, Q7Z7G7, Q8NB77, Q9NWV1, Q9Y4E7	Gene names	VPS13B, CHS1, COH1, KIAA0532
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1).

ZEP1_HUMAN
θ value	5.27518 (rank : 505)	NC score	0.003994 (rank : 967)
Query Neighborhood Hits	557	Target Neighborhood Hits	1036	Shared Neighborhood Hits	70
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

ZFY_HUMAN
θ value	5.27518 (rank : 506)	NC score	-0.003199 (rank : 987)
Query Neighborhood Hits	557	Target Neighborhood Hits	752	Shared Neighborhood Hits	28
SwissProt Accessions	P08048, Q14021, Q15558, Q96TF3	Gene names	ZFY
Domain Architecture
Description	Zinc finger Y-chromosomal protein.

BCAR1_MOUSE
θ value	6.88961 (rank : 507)	NC score	0.021116 (rank : 897)
Query Neighborhood Hits	557	Target Neighborhood Hits	438	Shared Neighborhood Hits	48
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CASC3_MOUSE
θ value	6.88961 (rank : 508)	NC score	0.021271 (rank : 894)
Query Neighborhood Hits	557	Target Neighborhood Hits	333	Shared Neighborhood Hits	43
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

CBP_HUMAN
θ value	6.88961 (rank : 509)	NC score	0.057444 (rank : 724)
Query Neighborhood Hits	557	Target Neighborhood Hits	941	Shared Neighborhood Hits	132
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CDC27_HUMAN
θ value	6.88961 (rank : 510)	NC score	0.005660 (rank : 960)
Query Neighborhood Hits	557	Target Neighborhood Hits	139	Shared Neighborhood Hits	12
SwissProt Accessions	P30260, Q16349, Q96F35	Gene names	CDC27
Domain Architecture
Description	Cell division cycle protein 27 homolog (CDC27Hs) (H-NUC).

CIC_MOUSE
θ value	6.88961 (rank : 511)	NC score	0.061318 (rank : 681)
Query Neighborhood Hits	557	Target Neighborhood Hits	742	Shared Neighborhood Hits	128
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CO8A_HUMAN
θ value	6.88961 (rank : 512)	NC score	0.079967 (rank : 555)
Query Neighborhood Hits	557	Target Neighborhood Hits	200	Shared Neighborhood Hits	83
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

DIDO1_HUMAN
θ value	6.88961 (rank : 513)	NC score	0.024391 (rank : 886)
Query Neighborhood Hits	557	Target Neighborhood Hits	960	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

EDIL3_MOUSE
θ value	6.88961 (rank : 514)	NC score	0.419917 (rank : 169)
Query Neighborhood Hits	557	Target Neighborhood Hits	317	Shared Neighborhood Hits	204
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EVI2A_MOUSE
θ value	6.88961 (rank : 515)	NC score	0.009812 (rank : 941)
Query Neighborhood Hits	557	Target Neighborhood Hits	34	Shared Neighborhood Hits	6
SwissProt Accessions	P20934	Gene names	Evi2a, Evi-2, Evi-2a, Evi2
Domain Architecture
Description	EVI2A protein precursor (Ecotropic viral integration site 2A protein).

FHOD1_HUMAN
θ value	6.88961 (rank : 516)	NC score	0.011045 (rank : 934)
Query Neighborhood Hits	557	Target Neighborhood Hits	184	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

GAK11_HUMAN
θ value	6.88961 (rank : 517)	NC score	0.008839 (rank : 949)
Query Neighborhood Hits	557	Target Neighborhood Hits	409	Shared Neighborhood Hits	42
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
θ value	6.88961 (rank : 518)	NC score	0.008705 (rank : 950)
Query Neighborhood Hits	557	Target Neighborhood Hits	406	Shared Neighborhood Hits	41
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
θ value	6.88961 (rank : 519)	NC score	0.008988 (rank : 944)
Query Neighborhood Hits	557	Target Neighborhood Hits	415	Shared Neighborhood Hits	42
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GP1BA_HUMAN
θ value	6.88961 (rank : 520)	NC score	0.038153 (rank : 851)
Query Neighborhood Hits	557	Target Neighborhood Hits	407	Shared Neighborhood Hits	60
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

GRIN1_HUMAN
θ value	6.88961 (rank : 521)	NC score	0.030856 (rank : 863)
Query Neighborhood Hits	557	Target Neighborhood Hits	681	Shared Neighborhood Hits	64
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

K1219_HUMAN
θ value	6.88961 (rank : 522)	NC score	0.015975 (rank : 916)
Query Neighborhood Hits	557	Target Neighborhood Hits	85	Shared Neighborhood Hits	17
SwissProt Accessions	Q86X10, Q5TG31, Q8N3D1, Q8WWC0, Q9H3X8, Q9UJR1, Q9ULK1, Q9Y3G9	Gene names	KIAA1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

LHX2_HUMAN
θ value	6.88961 (rank : 523)	NC score	0.004523 (rank : 965)
Query Neighborhood Hits	557	Target Neighborhood Hits	432	Shared Neighborhood Hits	19
SwissProt Accessions	P50458, O95860, Q8N1Z3	Gene names	LHX2, LH2
Domain Architecture
Description	LIM/homeobox protein Lhx2 (Homeobox protein LH-2).

LHX2_MOUSE
θ value	6.88961 (rank : 524)	NC score	0.004530 (rank : 964)
Query Neighborhood Hits	557	Target Neighborhood Hits	431	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z0S2	Gene names	Lhx2
Domain Architecture
Description	LIM/homeobox protein Lhx2.

MATN4_MOUSE
θ value	6.88961 (rank : 525)	NC score	0.283468 (rank : 253)
Query Neighborhood Hits	557	Target Neighborhood Hits	277	Shared Neighborhood Hits	161
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

PAK4_MOUSE
θ value	6.88961 (rank : 526)	NC score	0.005627 (rank : 961)
Query Neighborhood Hits	557	Target Neighborhood Hits	1098	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

PAPOG_MOUSE
θ value	6.88961 (rank : 527)	NC score	0.009264 (rank : 943)
Query Neighborhood Hits	557	Target Neighborhood Hits	103	Shared Neighborhood Hits	17
SwissProt Accessions	Q6PCL9, Q8BZC9	Gene names	Papolg
Domain Architecture	No domain graphic available
Description	Poly(A) polymerase gamma (EC 2.7.7.19) (PAP gamma) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3' adenylating enzyme).

PROP_MOUSE
θ value	6.88961 (rank : 528)	NC score	0.040716 (rank : 843)
Query Neighborhood Hits	557	Target Neighborhood Hits	165	Shared Neighborhood Hits	44
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

RIMB1_MOUSE
θ value	6.88961 (rank : 529)	NC score	0.022890 (rank : 891)
Query Neighborhood Hits	557	Target Neighborhood Hits	1376	Shared Neighborhood Hits	63
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RIPK3_MOUSE
θ value	6.88961 (rank : 530)	NC score	0.008929 (rank : 946)
Query Neighborhood Hits	557	Target Neighborhood Hits	867	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QZL0	Gene names	Ripk3, Rip3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3).

SEM6B_HUMAN
θ value	6.88961 (rank : 531)	NC score	0.002736 (rank : 972)
Query Neighborhood Hits	557	Target Neighborhood Hits	187	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

SMAD4_MOUSE
θ value	6.88961 (rank : 532)	NC score	0.003880 (rank : 968)
Query Neighborhood Hits	557	Target Neighborhood Hits	101	Shared Neighborhood Hits	15
SwissProt Accessions	P97471, Q9CW56	Gene names	Smad4, Dpc4, Madh4
Domain Architecture
Description	Mothers against decapentaplegic homolog 4 (SMAD 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4 homolog) (Smad4).

SPEG_HUMAN
θ value	6.88961 (rank : 533)	NC score	0.024130 (rank : 888)
Query Neighborhood Hits	557	Target Neighborhood Hits	1762	Shared Neighborhood Hits	154
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

T22D4_HUMAN
θ value	6.88961 (rank : 534)	NC score	0.024516 (rank : 883)
Query Neighborhood Hits	557	Target Neighborhood Hits	403	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

ZN217_HUMAN
θ value	6.88961 (rank : 535)	NC score	-0.001865 (rank : 979)
Query Neighborhood Hits	557	Target Neighborhood Hits	905	Shared Neighborhood Hits	57
SwissProt Accessions	O75362	Gene names	ZNF217, ZABC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 217.

ZN385_HUMAN
θ value	6.88961 (rank : 536)	NC score	0.013883 (rank : 926)
Query Neighborhood Hits	557	Target Neighborhood Hits	614	Shared Neighborhood Hits	41
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

ZNF77_HUMAN
θ value	6.88961 (rank : 537)	NC score	-0.002458 (rank : 980)
Query Neighborhood Hits	557	Target Neighborhood Hits	759	Shared Neighborhood Hits	40
SwissProt Accessions	Q15935, Q86XJ3, Q9NPP0	Gene names	ZNF77
Domain Architecture	No domain graphic available
Description	Zinc finger protein 77 (ZNFpT1).

ADA33_MOUSE
θ value	8.99809 (rank : 538)	NC score	0.105401 (rank : 456)
Query Neighborhood Hits	557	Target Neighborhood Hits	231	Shared Neighborhood Hits	139
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADAM8_HUMAN
θ value	8.99809 (rank : 539)	NC score	0.132809 (rank : 391)
Query Neighborhood Hits	557	Target Neighborhood Hits	327	Shared Neighborhood Hits	184
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

AKAP1_MOUSE
θ value	8.99809 (rank : 540)	NC score	0.009956 (rank : 940)
Query Neighborhood Hits	557	Target Neighborhood Hits	198	Shared Neighborhood Hits	26
SwissProt Accessions	O08715, O08714, P97488	Gene names	Akap1, Akap
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein) (S-AKAP).

BASI_MOUSE
θ value	8.99809 (rank : 541)	NC score	0.013431 (rank : 929)
Query Neighborhood Hits	557	Target Neighborhood Hits	238	Shared Neighborhood Hits	15
SwissProt Accessions	P18572, Q6LDB0, Q7TSC0	Gene names	Bsg
Domain Architecture
Description	Basigin precursor (Basic immunoglobulin superfamily) (Membrane glycoprotein gp42) (HT7 antigen) (CD147 antigen).

DACT1_HUMAN
θ value	8.99809 (rank : 542)	NC score	0.015533 (rank : 918)
Query Neighborhood Hits	557	Target Neighborhood Hits	228	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NYF0, Q86TY0	Gene names	DACT1, DPR1, HNG3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene 3 protein).

EMSY_MOUSE
θ value	8.99809 (rank : 543)	NC score	0.030426 (rank : 864)
Query Neighborhood Hits	557	Target Neighborhood Hits	294	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

EPN3_HUMAN
θ value	8.99809 (rank : 544)	NC score	0.017590 (rank : 912)
Query Neighborhood Hits	557	Target Neighborhood Hits	197	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

FA10_HUMAN
θ value	8.99809 (rank : 545)	NC score	0.159286 (rank : 354)
Query Neighborhood Hits	557	Target Neighborhood Hits	431	Shared Neighborhood Hits	177
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

GAK6_HUMAN
θ value	8.99809 (rank : 546)	NC score	0.008148 (rank : 953)
Query Neighborhood Hits	557	Target Neighborhood Hits	392	Shared Neighborhood Hits	41
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAS6_MOUSE
θ value	8.99809 (rank : 547)	NC score	0.434405 (rank : 164)
Query Neighborhood Hits	557	Target Neighborhood Hits	343	Shared Neighborhood Hits	220
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

ITSN1_HUMAN
θ value	8.99809 (rank : 548)	NC score	0.008850 (rank : 947)
Query Neighborhood Hits	557	Target Neighborhood Hits	1757	Shared Neighborhood Hits	65
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

JHD2B_HUMAN
θ value	8.99809 (rank : 549)	NC score	0.004132 (rank : 966)
Query Neighborhood Hits	557	Target Neighborhood Hits	171	Shared Neighborhood Hits	21
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

KAISO_HUMAN
θ value	8.99809 (rank : 550)	NC score	-0.005388 (rank : 990)
Query Neighborhood Hits	557	Target Neighborhood Hits	840	Shared Neighborhood Hits	44
SwissProt Accessions	Q86T24, O00319, Q7Z361, Q8IVP6, Q8N3P0	Gene names	ZBTB33, KAISO, ZNF348
Domain Architecture	No domain graphic available
Description	Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33).

MRCKB_MOUSE
θ value	8.99809 (rank : 551)	NC score	0.014569 (rank : 921)
Query Neighborhood Hits	557	Target Neighborhood Hits	2180	Shared Neighborhood Hits	88
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MTSS1_MOUSE
θ value	8.99809 (rank : 552)	NC score	0.024510 (rank : 884)
Query Neighborhood Hits	557	Target Neighborhood Hits	592	Shared Neighborhood Hits	56
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

PRG4_HUMAN
θ value	8.99809 (rank : 553)	NC score	0.111750 (rank : 437)
Query Neighborhood Hits	557	Target Neighborhood Hits	764	Shared Neighborhood Hits	160
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RTP3_MOUSE
θ value	8.99809 (rank : 554)	NC score	0.034364 (rank : 858)
Query Neighborhood Hits	557	Target Neighborhood Hits	374	Shared Neighborhood Hits	71
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

TITIN_HUMAN
θ value	8.99809 (rank : 555)	NC score	0.042201 (rank : 839)
Query Neighborhood Hits	557	Target Neighborhood Hits	2923	Shared Neighborhood Hits	175
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TNR5_HUMAN
θ value	8.99809 (rank : 556)	NC score	0.116384 (rank : 422)
Query Neighborhood Hits	557	Target Neighborhood Hits	102	Shared Neighborhood Hits	69
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

UBQL3_MOUSE
θ value	8.99809 (rank : 557)	NC score	0.006905 (rank : 956)
Query Neighborhood Hits	557	Target Neighborhood Hits	120	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C5U9	Gene names	Ubqln3
Domain Architecture
Description	Ubiquilin-3.

AD26A_MOUSE
θ value	θ > 10 (rank : 558)	NC score	0.065438 (rank : 643)
Query Neighborhood Hits	557	Target Neighborhood Hits	165	Shared Neighborhood Hits	96
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

ADA10_HUMAN
θ value	θ > 10 (rank : 559)	NC score	0.104402 (rank : 460)
Query Neighborhood Hits	557	Target Neighborhood Hits	189	Shared Neighborhood Hits	101
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ADA10_MOUSE
θ value	θ > 10 (rank : 560)	NC score	0.101554 (rank : 474)
Query Neighborhood Hits	557	Target Neighborhood Hits	194	Shared Neighborhood Hits	102
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA12_HUMAN
θ value	θ > 10 (rank : 561)	NC score	0.086088 (rank : 524)
Query Neighborhood Hits	557	Target Neighborhood Hits	224	Shared Neighborhood Hits	116
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA12_MOUSE
θ value	θ > 10 (rank : 562)	NC score	0.084772 (rank : 528)
Query Neighborhood Hits	557	Target Neighborhood Hits	474	Shared Neighborhood Hits	135
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA15_HUMAN
θ value	θ > 10 (rank : 563)	NC score	0.132372 (rank : 393)
Query Neighborhood Hits	557	Target Neighborhood Hits	288	Shared Neighborhood Hits	171
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

ADA15_MOUSE
θ value	θ > 10 (rank : 564)	NC score	0.139789 (rank : 375)
Query Neighborhood Hits	557	Target Neighborhood Hits	324	Shared Neighborhood Hits	199
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADA17_HUMAN
θ value	θ > 10 (rank : 565)	NC score	0.094643 (rank : 504)
Query Neighborhood Hits	557	Target Neighborhood Hits	223	Shared Neighborhood Hits	110
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ADA17_MOUSE
θ value	θ > 10 (rank : 566)	NC score	0.083025 (rank : 538)
Query Neighborhood Hits	557	Target Neighborhood Hits	201	Shared Neighborhood Hits	100
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

ADA18_HUMAN
θ value	θ > 10 (rank : 567)	NC score	0.086852 (rank : 519)
Query Neighborhood Hits	557	Target Neighborhood Hits	184	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

ADA18_MOUSE
θ value	θ > 10 (rank : 568)	NC score	0.103003 (rank : 467)
Query Neighborhood Hits	557	Target Neighborhood Hits	227	Shared Neighborhood Hits	132
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ADA20_HUMAN
θ value	θ > 10 (rank : 569)	NC score	0.055872 (rank : 737)
Query Neighborhood Hits	557	Target Neighborhood Hits	143	Shared Neighborhood Hits	73
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

ADA21_HUMAN
θ value	θ > 10 (rank : 570)	NC score	0.076673 (rank : 576)
Query Neighborhood Hits	557	Target Neighborhood Hits	181	Shared Neighborhood Hits	108
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

ADA24_MOUSE
θ value	θ > 10 (rank : 571)	NC score	0.088433 (rank : 517)
Query Neighborhood Hits	557	Target Neighborhood Hits	230	Shared Neighborhood Hits	131
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ADA29_HUMAN
θ value	θ > 10 (rank : 572)	NC score	0.075694 (rank : 583)
Query Neighborhood Hits	557	Target Neighborhood Hits	247	Shared Neighborhood Hits	116
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

ADA30_HUMAN
θ value	θ > 10 (rank : 573)	NC score	0.081951 (rank : 544)
Query Neighborhood Hits	557	Target Neighborhood Hits	391	Shared Neighborhood Hits	115
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ADA32_HUMAN
θ value	θ > 10 (rank : 574)	NC score	0.087712 (rank : 518)
Query Neighborhood Hits	557	Target Neighborhood Hits	216	Shared Neighborhood Hits	126
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA32_MOUSE
θ value	θ > 10 (rank : 575)	NC score	0.081754 (rank : 545)
Query Neighborhood Hits	557	Target Neighborhood Hits	219	Shared Neighborhood Hits	124
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADAM2_HUMAN
θ value	θ > 10 (rank : 576)	NC score	0.076819 (rank : 574)
Query Neighborhood Hits	557	Target Neighborhood Hits	175	Shared Neighborhood Hits	100
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

ADAM2_MOUSE
θ value	θ > 10 (rank : 577)	NC score	0.100450 (rank : 479)
Query Neighborhood Hits	557	Target Neighborhood Hits	209	Shared Neighborhood Hits	121
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

ADAM8_MOUSE
θ value	θ > 10 (rank : 578)	NC score	0.134277 (rank : 385)
Query Neighborhood Hits	557	Target Neighborhood Hits	326	Shared Neighborhood Hits	177
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

ADAM9_HUMAN
θ value	θ > 10 (rank : 579)	NC score	0.105223 (rank : 458)
Query Neighborhood Hits	557	Target Neighborhood Hits	243	Shared Neighborhood Hits	134
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

ADAM9_MOUSE
θ value	θ > 10 (rank : 580)	NC score	0.113168 (rank : 433)
Query Neighborhood Hits	557	Target Neighborhood Hits	325	Shared Neighborhood Hits	152
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ADM1B_MOUSE
θ value	θ > 10 (rank : 581)	NC score	0.079990 (rank : 554)
Query Neighborhood Hits	557	Target Neighborhood Hits	236	Shared Neighborhood Hits	112
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

ALEX_HUMAN
θ value	θ > 10 (rank : 582)	NC score	0.052788 (rank : 782)
Query Neighborhood Hits	557	Target Neighborhood Hits	361	Shared Neighborhood Hits	79
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

APR3_HUMAN
θ value	θ > 10 (rank : 583)	NC score	0.095027 (rank : 501)
Query Neighborhood Hits	557	Target Neighborhood Hits	50	Shared Neighborhood Hits	45
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

APR3_MOUSE
θ value	θ > 10 (rank : 584)	NC score	0.109488 (rank : 443)
Query Neighborhood Hits	557	Target Neighborhood Hits	61	Shared Neighborhood Hits	51
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

ASTN_HUMAN
θ value	θ > 10 (rank : 585)	NC score	0.076248 (rank : 579)
Query Neighborhood Hits	557	Target Neighborhood Hits	105	Shared Neighborhood Hits	56
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

ASTN_MOUSE
θ value	θ > 10 (rank : 586)	NC score	0.077314 (rank : 571)
Query Neighborhood Hits	557	Target Neighborhood Hits	98	Shared Neighborhood Hits	56
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

ATN1_HUMAN
θ value	θ > 10 (rank : 587)	NC score	0.075910 (rank : 582)
Query Neighborhood Hits	557	Target Neighborhood Hits	676	Shared Neighborhood Hits	107
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BAI1_HUMAN
θ value	θ > 10 (rank : 588)	NC score	0.076705 (rank : 575)
Query Neighborhood Hits	557	Target Neighborhood Hits	375	Shared Neighborhood Hits	97
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_MOUSE
θ value	θ > 10 (rank : 589)	NC score	0.070486 (rank : 613)
Query Neighborhood Hits	557	Target Neighborhood Hits	340	Shared Neighborhood Hits	78
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI2_HUMAN
θ value	θ > 10 (rank : 590)	NC score	0.056652 (rank : 729)
Query Neighborhood Hits	557	Target Neighborhood Hits	332	Shared Neighborhood Hits	52
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_MOUSE
θ value	θ > 10 (rank : 591)	NC score	0.058701 (rank : 706)
Query Neighborhood Hits	557	Target Neighborhood Hits	323	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI3_HUMAN
θ value	θ > 10 (rank : 592)	NC score	0.060223 (rank : 687)
Query Neighborhood Hits	557	Target Neighborhood Hits	246	Shared Neighborhood Hits	43
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
θ value	θ > 10 (rank : 593)	NC score	0.062019 (rank : 675)
Query Neighborhood Hits	557	Target Neighborhood Hits	250	Shared Neighborhood Hits	46
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BASP_MOUSE
θ value	θ > 10 (rank : 594)	NC score	0.069532 (rank : 619)
Query Neighborhood Hits	557	Target Neighborhood Hits	260	Shared Neighborhood Hits	51
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BAT2_HUMAN
θ value	θ > 10 (rank : 595)	NC score	0.060623 (rank : 685)
Query Neighborhood Hits	557	Target Neighborhood Hits	931	Shared Neighborhood Hits	116
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BMP1_HUMAN
θ value	θ > 10 (rank : 596)	NC score	0.107230 (rank : 450)
Query Neighborhood Hits	557	Target Neighborhood Hits	233	Shared Neighborhood Hits	114
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	θ > 10 (rank : 597)	NC score	0.108154 (rank : 446)
Query Neighborhood Hits	557	Target Neighborhood Hits	236	Shared Neighborhood Hits	115
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMPER_MOUSE
θ value	θ > 10 (rank : 598)	NC score	0.173705 (rank : 340)
Query Neighborhood Hits	557	Target Neighborhood Hits	194	Shared Neighborhood Hits	112
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

BTC_HUMAN
θ value	θ > 10 (rank : 599)	NC score	0.062973 (rank : 664)
Query Neighborhood Hits	557	Target Neighborhood Hits	70	Shared Neighborhood Hits	40
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

BTC_MOUSE
θ value	θ > 10 (rank : 600)	NC score	0.065173 (rank : 646)
Query Neighborhood Hits	557	Target Neighborhood Hits	67	Shared Neighborhood Hits	41
SwissProt Accessions	Q05928	Gene names	Btc, Bcn
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

C1RA_MOUSE
θ value	θ > 10 (rank : 601)	NC score	0.055537 (rank : 743)
Query Neighborhood Hits	557	Target Neighborhood Hits	379	Shared Neighborhood Hits	105
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1RB_MOUSE
θ value	θ > 10 (rank : 602)	NC score	0.054644 (rank : 759)
Query Neighborhood Hits	557	Target Neighborhood Hits	380	Shared Neighborhood Hits	105
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

CAD23_HUMAN
θ value	θ > 10 (rank : 603)	NC score	0.050882 (rank : 809)
Query Neighborhood Hits	557	Target Neighborhood Hits	197	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H251, Q6UWW1, Q9H4K9	Gene names	CDH23, KIAA1774
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

CAD23_MOUSE
θ value	θ > 10 (rank : 604)	NC score	0.051159 (rank : 805)
Query Neighborhood Hits	557	Target Neighborhood Hits	208	Shared Neighborhood Hits	18
SwissProt Accessions	Q99PF4, Q99NH1, Q9D4N9	Gene names	Cdh23
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

CCNK_MOUSE
θ value	θ > 10 (rank : 605)	NC score	0.051915 (rank : 798)
Query Neighborhood Hits	557	Target Neighborhood Hits	350	Shared Neighborhood Hits	81
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CD320_HUMAN
θ value	θ > 10 (rank : 606)	NC score	0.096963 (rank : 494)
Query Neighborhood Hits	557	Target Neighborhood Hits	103	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

CD97_HUMAN
θ value	θ > 10 (rank : 607)	NC score	0.340557 (rank : 215)
Query Neighborhood Hits	557	Target Neighborhood Hits	353	Shared Neighborhood Hits	193
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CD97_MOUSE
θ value	θ > 10 (rank : 608)	NC score	0.268011 (rank : 269)
Query Neighborhood Hits	557	Target Neighborhood Hits	295	Shared Neighborhood Hits	157
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CDN1C_HUMAN
θ value	θ > 10 (rank : 609)	NC score	0.065302 (rank : 645)
Query Neighborhood Hits	557	Target Neighborhood Hits	168	Shared Neighborhood Hits	54
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CFC1_HUMAN
θ value	θ > 10 (rank : 610)	NC score	0.266828 (rank : 271)
Query Neighborhood Hits	557	Target Neighborhood Hits	148	Shared Neighborhood Hits	119
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CFC1_MOUSE
θ value	θ > 10 (rank : 611)	NC score	0.233605 (rank : 295)
Query Neighborhood Hits	557	Target Neighborhood Hits	125	Shared Neighborhood Hits	104
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CHRD_HUMAN
θ value	θ > 10 (rank : 612)	NC score	0.101580 (rank : 473)
Query Neighborhood Hits	557	Target Neighborhood Hits	102	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

CHRD_MOUSE
θ value	θ > 10 (rank : 613)	NC score	0.105883 (rank : 455)
Query Neighborhood Hits	557	Target Neighborhood Hits	102	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

CIC_HUMAN
θ value	θ > 10 (rank : 614)	NC score	0.053960 (rank : 766)
Query Neighborhood Hits	557	Target Neighborhood Hits	992	Shared Neighborhood Hits	130
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CJ078_MOUSE
θ value	θ > 10 (rank : 615)	NC score	0.069797 (rank : 617)
Query Neighborhood Hits	557	Target Neighborhood Hits	559	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CJ095_HUMAN
θ value	θ > 10 (rank : 616)	NC score	0.062870 (rank : 665)
Query Neighborhood Hits	557	Target Neighborhood Hits	50	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H7T3	Gene names	C10orf95
Domain Architecture	No domain graphic available
Description	Protein C10orf95.

CLC14_HUMAN
θ value	θ > 10 (rank : 617)	NC score	0.106745 (rank : 453)
Query Neighborhood Hits	557	Target Neighborhood Hits	143	Shared Neighborhood Hits	80
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

CLC14_MOUSE
θ value	θ > 10 (rank : 618)	NC score	0.109130 (rank : 444)
Query Neighborhood Hits	557	Target Neighborhood Hits	120	Shared Neighborhood Hits	73
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

CLC4F_HUMAN
θ value	θ > 10 (rank : 619)	NC score	0.055868 (rank : 738)
Query Neighborhood Hits	557	Target Neighborhood Hits	513	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N1N0	Gene names	CLEC4F, CLECSF13
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13).

CLC4F_MOUSE
θ value	θ > 10 (rank : 620)	NC score	0.050621 (rank : 813)
Query Neighborhood Hits	557	Target Neighborhood Hits	572	Shared Neighborhood Hits	32
SwissProt Accessions	P70194, Q8BLZ8	Gene names	Clec4f, Clecsf13, Kclr
Domain Architecture
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13) (Kupffer cell receptor).

CN032_HUMAN
θ value	θ > 10 (rank : 621)	NC score	0.088909 (rank : 516)
Query Neighborhood Hits	557	Target Neighborhood Hits	267	Shared Neighborhood Hits	74
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CN032_MOUSE
θ value	θ > 10 (rank : 622)	NC score	0.089527 (rank : 514)
Query Neighborhood Hits	557	Target Neighborhood Hits	233	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CN155_HUMAN
θ value	θ > 10 (rank : 623)	NC score	0.056710 (rank : 728)
Query Neighborhood Hits	557	Target Neighborhood Hits	385	Shared Neighborhood Hits	66
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CNTP1_HUMAN
θ value	θ > 10 (rank : 624)	NC score	0.185269 (rank : 331)
Query Neighborhood Hits	557	Target Neighborhood Hits	196	Shared Neighborhood Hits	108
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

CNTP1_MOUSE
θ value	θ > 10 (rank : 625)	NC score	0.182421 (rank : 336)
Query Neighborhood Hits	557	Target Neighborhood Hits	183	Shared Neighborhood Hits	103
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

CNTP2_HUMAN
θ value	θ > 10 (rank : 626)	NC score	0.217694 (rank : 307)
Query Neighborhood Hits	557	Target Neighborhood Hits	199	Shared Neighborhood Hits	114
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP2_MOUSE
θ value	θ > 10 (rank : 627)	NC score	0.221020 (rank : 305)
Query Neighborhood Hits	557	Target Neighborhood Hits	194	Shared Neighborhood Hits	113
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP3_HUMAN
θ value	θ > 10 (rank : 628)	NC score	0.187830 (rank : 329)
Query Neighborhood Hits	557	Target Neighborhood Hits	195	Shared Neighborhood Hits	105
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

CNTP4_HUMAN
θ value	θ > 10 (rank : 629)	NC score	0.212520 (rank : 311)
Query Neighborhood Hits	557	Target Neighborhood Hits	187	Shared Neighborhood Hits	101
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CNTP4_MOUSE
θ value	θ > 10 (rank : 630)	NC score	0.208282 (rank : 314)
Query Neighborhood Hits	557	Target Neighborhood Hits	193	Shared Neighborhood Hits	110
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CO7A1_HUMAN
θ value	θ > 10 (rank : 631)	NC score	0.062782 (rank : 667)
Query Neighborhood Hits	557	Target Neighborhood Hits	807	Shared Neighborhood Hits	112
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CO7_HUMAN
θ value	θ > 10 (rank : 632)	NC score	0.122221 (rank : 410)
Query Neighborhood Hits	557	Target Neighborhood Hits	278	Shared Neighborhood Hits	114
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO8A_MOUSE
θ value	θ > 10 (rank : 633)	NC score	0.063003 (rank : 663)
Query Neighborhood Hits	557	Target Neighborhood Hits	182	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8B_HUMAN
θ value	θ > 10 (rank : 634)	NC score	0.071653 (rank : 605)
Query Neighborhood Hits	557	Target Neighborhood Hits	199	Shared Neighborhood Hits	70
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO8B_MOUSE
θ value	θ > 10 (rank : 635)	NC score	0.105387 (rank : 457)
Query Neighborhood Hits	557	Target Neighborhood Hits	224	Shared Neighborhood Hits	94
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO9_HUMAN
θ value	θ > 10 (rank : 636)	NC score	0.074923 (rank : 588)
Query Neighborhood Hits	557	Target Neighborhood Hits	147	Shared Neighborhood Hits	64
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

CO9_MOUSE
θ value	θ > 10 (rank : 637)	NC score	0.074375 (rank : 592)
Query Neighborhood Hits	557	Target Neighborhood Hits	153	Shared Neighborhood Hits	68
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

COCA1_HUMAN
θ value	θ > 10 (rank : 638)	NC score	0.066865 (rank : 632)
Query Neighborhood Hits	557	Target Neighborhood Hits	458	Shared Neighborhood Hits	74
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COCA1_MOUSE
θ value	θ > 10 (rank : 639)	NC score	0.070094 (rank : 614)
Query Neighborhood Hits	557	Target Neighborhood Hits	467	Shared Neighborhood Hits	83
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COEA1_HUMAN
θ value	θ > 10 (rank : 640)	NC score	0.059722 (rank : 693)
Query Neighborhood Hits	557	Target Neighborhood Hits	427	Shared Neighborhood Hits	69
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

COEA1_MOUSE
θ value	θ > 10 (rank : 641)	NC score	0.061553 (rank : 679)
Query Neighborhood Hits	557	Target Neighborhood Hits	402	Shared Neighborhood Hits	57
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

COKA1_HUMAN
θ value	θ > 10 (rank : 642)	NC score	0.056594 (rank : 732)
Query Neighborhood Hits	557	Target Neighborhood Hits	403	Shared Neighborhood Hits	58
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

CORIN_MOUSE
θ value	θ > 10 (rank : 643)	NC score	0.113244 (rank : 432)
Query Neighborhood Hits	557	Target Neighborhood Hits	451	Shared Neighborhood Hits	158
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

CPSF6_HUMAN
θ value	θ > 10 (rank : 644)	NC score	0.053672 (rank : 772)
Query Neighborhood Hits	557	Target Neighborhood Hits	359	Shared Neighborhood Hits	68
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	θ > 10 (rank : 645)	NC score	0.055008 (rank : 753)
Query Neighborhood Hits	557	Target Neighborhood Hits	356	Shared Neighborhood Hits	69
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CRAC1_HUMAN
θ value	θ > 10 (rank : 646)	NC score	0.123297 (rank : 407)
Query Neighborhood Hits	557	Target Neighborhood Hits	111	Shared Neighborhood Hits	68
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRAC1_MOUSE
θ value	θ > 10 (rank : 647)	NC score	0.125045 (rank : 404)
Query Neighborhood Hits	557	Target Neighborhood Hits	112	Shared Neighborhood Hits	70
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRDL1_HUMAN
θ value	θ > 10 (rank : 648)	NC score	0.051165 (rank : 804)
Query Neighborhood Hits	557	Target Neighborhood Hits	75	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BU40, Q9Y3H7	Gene names	CHRDL1, NRLN1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CRDL2_HUMAN
θ value	θ > 10 (rank : 649)	NC score	0.054945 (rank : 754)
Query Neighborhood Hits	557	Target Neighborhood Hits	99	Shared Neighborhood Hits	34
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

CRDL2_MOUSE
θ value	θ > 10 (rank : 650)	NC score	0.059990 (rank : 688)
Query Neighborhood Hits	557	Target Neighborhood Hits	81	Shared Neighborhood Hits	35
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

CS016_HUMAN
θ value	θ > 10 (rank : 651)	NC score	0.062241 (rank : 674)
Query Neighborhood Hits	557	Target Neighborhood Hits	310	Shared Neighborhood Hits	80
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

CSKI1_HUMAN
θ value	θ > 10 (rank : 652)	NC score	0.056619 (rank : 731)
Query Neighborhood Hits	557	Target Neighborhood Hits	997	Shared Neighborhood Hits	136
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI1_MOUSE
θ value	θ > 10 (rank : 653)	NC score	0.057856 (rank : 715)
Query Neighborhood Hits	557	Target Neighborhood Hits	1031	Shared Neighborhood Hits	142
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSPG4_HUMAN
θ value	θ > 10 (rank : 654)	NC score	0.104541 (rank : 459)
Query Neighborhood Hits	557	Target Neighborhood Hits	112	Shared Neighborhood Hits	29
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

CSPG4_MOUSE
θ value	θ > 10 (rank : 655)	NC score	0.099822 (rank : 484)
Query Neighborhood Hits	557	Target Neighborhood Hits	105	Shared Neighborhood Hits	34
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

CT127_HUMAN
θ value	θ > 10 (rank : 656)	NC score	0.142733 (rank : 370)
Query Neighborhood Hits	557	Target Neighborhood Hits	67	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

CTGF_HUMAN
θ value	θ > 10 (rank : 657)	NC score	0.052470 (rank : 789)
Query Neighborhood Hits	557	Target Neighborhood Hits	128	Shared Neighborhood Hits	50
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

CYR61_HUMAN
θ value	θ > 10 (rank : 658)	NC score	0.072798 (rank : 598)
Query Neighborhood Hits	557	Target Neighborhood Hits	159	Shared Neighborhood Hits	63
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

CYR61_MOUSE
θ value	θ > 10 (rank : 659)	NC score	0.075262 (rank : 585)
Query Neighborhood Hits	557	Target Neighborhood Hits	156	Shared Neighborhood Hits	62
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

DCC_HUMAN
θ value	θ > 10 (rank : 660)	NC score	0.054190 (rank : 761)
Query Neighborhood Hits	557	Target Neighborhood Hits	583	Shared Neighborhood Hits	67
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

DGKK_HUMAN
θ value	θ > 10 (rank : 661)	NC score	0.053443 (rank : 776)
Query Neighborhood Hits	557	Target Neighborhood Hits	378	Shared Neighborhood Hits	83
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

DKK3_HUMAN
θ value	θ > 10 (rank : 662)	NC score	0.079903 (rank : 556)
Query Neighborhood Hits	557	Target Neighborhood Hits	74	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UBP4, Q9ULB7	Gene names	DKK3, REIC
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3).

DKK3_MOUSE
θ value	θ > 10 (rank : 663)	NC score	0.084851 (rank : 527)
Query Neighborhood Hits	557	Target Neighborhood Hits	83	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

DSCAM_HUMAN
θ value	θ > 10 (rank : 664)	NC score	0.050265 (rank : 820)
Query Neighborhood Hits	557	Target Neighborhood Hits	524	Shared Neighborhood Hits	47
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

DSCL1_HUMAN
θ value	θ > 10 (rank : 665)	NC score	0.054658 (rank : 758)
Query Neighborhood Hits	557	Target Neighborhood Hits	589	Shared Neighborhood Hits	75
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

EDIL3_HUMAN
θ value	θ > 10 (rank : 666)	NC score	0.385747 (rank : 189)
Query Neighborhood Hits	557	Target Neighborhood Hits	292	Shared Neighborhood Hits	186
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EGFL8_HUMAN
θ value	θ > 10 (rank : 667)	NC score	0.371795 (rank : 196)
Query Neighborhood Hits	557	Target Neighborhood Hits	270	Shared Neighborhood Hits	173
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL8_MOUSE
θ value	θ > 10 (rank : 668)	NC score	0.364789 (rank : 201)
Query Neighborhood Hits	557	Target Neighborhood Hits	266	Shared Neighborhood Hits	174
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EGFR_HUMAN
θ value	θ > 10 (rank : 669)	NC score	0.050330 (rank : 818)
Query Neighborhood Hits	557	Target Neighborhood Hits	939	Shared Neighborhood Hits	102
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

EGF_HUMAN
θ value	θ > 10 (rank : 670)	NC score	0.355151 (rank : 208)
Query Neighborhood Hits	557	Target Neighborhood Hits	343	Shared Neighborhood Hits	209
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EMR1_MOUSE
θ value	θ > 10 (rank : 671)	NC score	0.323765 (rank : 223)
Query Neighborhood Hits	557	Target Neighborhood Hits	349	Shared Neighborhood Hits	180
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EMR2_HUMAN
θ value	θ > 10 (rank : 672)	NC score	0.343236 (rank : 212)
Query Neighborhood Hits	557	Target Neighborhood Hits	345	Shared Neighborhood Hits	192
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

EMR3_HUMAN
θ value	θ > 10 (rank : 673)	NC score	0.159862 (rank : 353)
Query Neighborhood Hits	557	Target Neighborhood Hits	245	Shared Neighborhood Hits	114
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

EMR4_MOUSE
θ value	θ > 10 (rank : 674)	NC score	0.120757 (rank : 412)
Query Neighborhood Hits	557	Target Neighborhood Hits	191	Shared Neighborhood Hits	88
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

ENAH_MOUSE
θ value	θ > 10 (rank : 675)	NC score	0.063290 (rank : 659)
Query Neighborhood Hits	557	Target Neighborhood Hits	919	Shared Neighborhood Hits	122
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

EP300_HUMAN
θ value	θ > 10 (rank : 676)	NC score	0.050884 (rank : 808)
Query Neighborhood Hits	557	Target Neighborhood Hits	821	Shared Neighborhood Hits	121
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

EPGN_HUMAN
θ value	θ > 10 (rank : 677)	NC score	0.052126 (rank : 796)
Query Neighborhood Hits	557	Target Neighborhood Hits	59	Shared Neighborhood Hits	35
SwissProt Accessions	Q6UW88	Gene names	EPGN
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

EPGN_MOUSE
θ value	θ > 10 (rank : 678)	NC score	0.065807 (rank : 642)
Query Neighborhood Hits	557	Target Neighborhood Hits	63	Shared Neighborhood Hits	38
SwissProt Accessions	Q924X1, Q8CEX5	Gene names	Epgn
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

EPHA5_HUMAN
θ value	θ > 10 (rank : 679)	NC score	0.051516 (rank : 801)
Query Neighborhood Hits	557	Target Neighborhood Hits	1009	Shared Neighborhood Hits	84
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

EPHA6_MOUSE
θ value	θ > 10 (rank : 680)	NC score	0.054059 (rank : 764)
Query Neighborhood Hits	557	Target Neighborhood Hits	946	Shared Neighborhood Hits	86
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHB4_MOUSE
θ value	θ > 10 (rank : 681)	NC score	0.066432 (rank : 637)
Query Neighborhood Hits	557	Target Neighborhood Hits	1013	Shared Neighborhood Hits	130
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

EREG_HUMAN
θ value	θ > 10 (rank : 682)	NC score	0.091261 (rank : 512)
Query Neighborhood Hits	557	Target Neighborhood Hits	73	Shared Neighborhood Hits	46
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

EREG_MOUSE
θ value	θ > 10 (rank : 683)	NC score	0.052503 (rank : 787)
Query Neighborhood Hits	557	Target Neighborhood Hits	65	Shared Neighborhood Hits	34
SwissProt Accessions	Q61521, Q7M0A8	Gene names	Ereg
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

FA12_HUMAN
θ value	θ > 10 (rank : 684)	NC score	0.144918 (rank : 363)
Query Neighborhood Hits	557	Target Neighborhood Hits	425	Shared Neighborhood Hits	177
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

FA7_HUMAN
θ value	θ > 10 (rank : 685)	NC score	0.143875 (rank : 368)
Query Neighborhood Hits	557	Target Neighborhood Hits	404	Shared Neighborhood Hits	169
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

FA7_MOUSE
θ value	θ > 10 (rank : 686)	NC score	0.120102 (rank : 414)
Query Neighborhood Hits	557	Target Neighborhood Hits	374	Shared Neighborhood Hits	146
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

FA9_HUMAN
θ value	θ > 10 (rank : 687)	NC score	0.151988 (rank : 360)
Query Neighborhood Hits	557	Target Neighborhood Hits	421	Shared Neighborhood Hits	170
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

FBLN4_HUMAN
θ value	θ > 10 (rank : 688)	NC score	0.386693 (rank : 188)
Query Neighborhood Hits	557	Target Neighborhood Hits	278	Shared Neighborhood Hits	188
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	θ > 10 (rank : 689)	NC score	0.378217 (rank : 194)
Query Neighborhood Hits	557	Target Neighborhood Hits	270	Shared Neighborhood Hits	182
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_MOUSE
θ value	θ > 10 (rank : 690)	NC score	0.386710 (rank : 187)
Query Neighborhood Hits	557	Target Neighborhood Hits	317	Shared Neighborhood Hits	208
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FMNL_HUMAN
θ value	θ > 10 (rank : 691)	NC score	0.054842 (rank : 756)
Query Neighborhood Hits	557	Target Neighborhood Hits	529	Shared Neighborhood Hits	93
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

FNDC3_HUMAN
θ value	θ > 10 (rank : 692)	NC score	0.075092 (rank : 586)
Query Neighborhood Hits	557	Target Neighborhood Hits	196	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FNDC3_MOUSE
θ value	θ > 10 (rank : 693)	NC score	0.077996 (rank : 567)
Query Neighborhood Hits	557	Target Neighborhood Hits	207	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FSTL3_HUMAN
θ value	θ > 10 (rank : 694)	NC score	0.141281 (rank : 372)
Query Neighborhood Hits	557	Target Neighborhood Hits	162	Shared Neighborhood Hits	87
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL3_MOUSE
θ value	θ > 10 (rank : 695)	NC score	0.132606 (rank : 392)
Query Neighborhood Hits	557	Target Neighborhood Hits	152	Shared Neighborhood Hits	81
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FST_HUMAN
θ value	θ > 10 (rank : 696)	NC score	0.092666 (rank : 509)
Query Neighborhood Hits	557	Target Neighborhood Hits	129	Shared Neighborhood Hits	55
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FST_MOUSE
θ value	θ > 10 (rank : 697)	NC score	0.102401 (rank : 470)
Query Neighborhood Hits	557	Target Neighborhood Hits	146	Shared Neighborhood Hits	71
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FURIN_HUMAN
θ value	θ > 10 (rank : 698)	NC score	0.052511 (rank : 786)
Query Neighborhood Hits	557	Target Neighborhood Hits	52	Shared Neighborhood Hits	22
SwissProt Accessions	P09958, Q14336, Q6LBS3	Gene names	FURIN, FUR, PACE
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme).

FURIN_MOUSE
θ value	θ > 10 (rank : 699)	NC score	0.052542 (rank : 785)
Query Neighborhood Hits	557	Target Neighborhood Hits	49	Shared Neighborhood Hits	19
SwissProt Accessions	P23188	Gene names	Furin, Fur, Pcsk3
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme) (Prohormone convertase 3).

GGN_HUMAN
θ value	θ > 10 (rank : 700)	NC score	0.086441 (rank : 520)
Query Neighborhood Hits	557	Target Neighborhood Hits	269	Shared Neighborhood Hits	79
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GGN_MOUSE
θ value	θ > 10 (rank : 701)	NC score	0.078354 (rank : 565)
Query Neighborhood Hits	557	Target Neighborhood Hits	311	Shared Neighborhood Hits	89
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GOGA1_HUMAN
θ value	θ > 10 (rank : 702)	NC score	0.051057 (rank : 806)
Query Neighborhood Hits	557	Target Neighborhood Hits	1222	Shared Neighborhood Hits	36
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GP113_HUMAN
θ value	θ > 10 (rank : 703)	NC score	0.056634 (rank : 730)
Query Neighborhood Hits	557	Target Neighborhood Hits	102	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IZF5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3	Gene names	GPR113, PGR23
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 113 precursor (G-protein coupled receptor PGR23).

GP114_HUMAN
θ value	θ > 10 (rank : 704)	NC score	0.050530 (rank : 814)
Query Neighborhood Hits	557	Target Neighborhood Hits	75	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IZF4, Q6ZMH7, Q6ZML4, Q86SL8, Q8IZ14	Gene names	GPR114, PGR27
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 114 precursor (G-protein coupled receptor PGR27).

GP116_HUMAN
θ value	θ > 10 (rank : 705)	NC score	0.055668 (rank : 741)
Query Neighborhood Hits	557	Target Neighborhood Hits	167	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

GP123_HUMAN
θ value	θ > 10 (rank : 706)	NC score	0.050091 (rank : 822)
Query Neighborhood Hits	557	Target Neighborhood Hits	120	Shared Neighborhood Hits	13
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

GP124_HUMAN
θ value	θ > 10 (rank : 707)	NC score	0.053367 (rank : 778)
Query Neighborhood Hits	557	Target Neighborhood Hits	304	Shared Neighborhood Hits	24
SwissProt Accessions	Q96PE1, Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4	Gene names	GPR124, KIAA1531, TEM5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GP124_MOUSE
θ value	θ > 10 (rank : 708)	NC score	0.053851 (rank : 769)
Query Neighborhood Hits	557	Target Neighborhood Hits	423	Shared Neighborhood Hits	33
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GP125_HUMAN
θ value	θ > 10 (rank : 709)	NC score	0.054664 (rank : 757)
Query Neighborhood Hits	557	Target Neighborhood Hits	327	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

GP125_MOUSE
θ value	θ > 10 (rank : 710)	NC score	0.050750 (rank : 812)
Query Neighborhood Hits	557	Target Neighborhood Hits	329	Shared Neighborhood Hits	22
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

GP128_HUMAN
θ value	θ > 10 (rank : 711)	NC score	0.070016 (rank : 615)
Query Neighborhood Hits	557	Target Neighborhood Hits	135	Shared Neighborhood Hits	40
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

GP128_MOUSE
θ value	θ > 10 (rank : 712)	NC score	0.074850 (rank : 589)
Query Neighborhood Hits	557	Target Neighborhood Hits	141	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BM96, Q80T42	Gene names	Gpr128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

GP133_HUMAN
θ value	θ > 10 (rank : 713)	NC score	0.059126 (rank : 697)
Query Neighborhood Hits	557	Target Neighborhood Hits	115	Shared Neighborhood Hits	10
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

GP144_HUMAN
θ value	θ > 10 (rank : 714)	NC score	0.063445 (rank : 657)
Query Neighborhood Hits	557	Target Neighborhood Hits	108	Shared Neighborhood Hits	13
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

GP179_HUMAN
θ value	θ > 10 (rank : 715)	NC score	0.052394 (rank : 791)
Query Neighborhood Hits	557	Target Neighborhood Hits	372	Shared Neighborhood Hits	71
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

GPR64_HUMAN
θ value	θ > 10 (rank : 716)	NC score	0.058788 (rank : 702)
Query Neighborhood Hits	557	Target Neighborhood Hits	207	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

GPR64_MOUSE
θ value	θ > 10 (rank : 717)	NC score	0.059935 (rank : 690)
Query Neighborhood Hits	557	Target Neighborhood Hits	156	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

GPR98_HUMAN
θ value	θ > 10 (rank : 718)	NC score	0.064786 (rank : 649)
Query Neighborhood Hits	557	Target Neighborhood Hits	202	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

GPR98_MOUSE
θ value	θ > 10 (rank : 719)	NC score	0.059071 (rank : 699)
Query Neighborhood Hits	557	Target Neighborhood Hits	206	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

GRN_HUMAN
θ value	θ > 10 (rank : 720)	NC score	0.326592 (rank : 220)
Query Neighborhood Hits	557	Target Neighborhood Hits	268	Shared Neighborhood Hits	162
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

GSCR1_HUMAN
θ value	θ > 10 (rank : 721)	NC score	0.094481 (rank : 505)
Query Neighborhood Hits	557	Target Neighborhood Hits	674	Shared Neighborhood Hits	132
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

HABP2_MOUSE
θ value	θ > 10 (rank : 722)	NC score	0.231103 (rank : 297)
Query Neighborhood Hits	557	Target Neighborhood Hits	445	Shared Neighborhood Hits	199
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HBEGF_HUMAN
θ value	θ > 10 (rank : 723)	NC score	0.053554 (rank : 774)
Query Neighborhood Hits	557	Target Neighborhood Hits	61	Shared Neighborhood Hits	38
SwissProt Accessions	Q99075	Gene names	HBEGF, DTR, HEGFL
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF) (Diphtheria toxin receptor) (DT-R).

HCFC2_HUMAN
θ value	θ > 10 (rank : 724)	NC score	0.057770 (rank : 716)
Query Neighborhood Hits	557	Target Neighborhood Hits	154	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y5Z7	Gene names	HCFC2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

HGFA_HUMAN
θ value	θ > 10 (rank : 725)	NC score	0.168916 (rank : 342)
Query Neighborhood Hits	557	Target Neighborhood Hits	436	Shared Neighborhood Hits	182
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HMCN1_HUMAN
θ value	θ > 10 (rank : 726)	NC score	0.253720 (rank : 281)
Query Neighborhood Hits	557	Target Neighborhood Hits	983	Shared Neighborhood Hits	243
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

HPLN2_HUMAN
θ value	θ > 10 (rank : 727)	NC score	0.050798 (rank : 811)
Query Neighborhood Hits	557	Target Neighborhood Hits	80	Shared Neighborhood Hits	12
SwissProt Accessions	Q9GZV7	Gene names	HAPLN2, BRAL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

HPLN2_MOUSE
θ value	θ > 10 (rank : 728)	NC score	0.051660 (rank : 799)
Query Neighborhood Hits	557	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ESM3	Gene names	Hapln2, Bral1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

IDD_HUMAN
θ value	θ > 10 (rank : 729)	NC score	0.050362 (rank : 816)
Query Neighborhood Hits	557	Target Neighborhood Hits	127	Shared Neighborhood Hits	33
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

IF35_MOUSE
θ value	θ > 10 (rank : 730)	NC score	0.057889 (rank : 714)
Query Neighborhood Hits	557	Target Neighborhood Hits	210	Shared Neighborhood Hits	69
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

INSRR_HUMAN
θ value	θ > 10 (rank : 731)	NC score	0.060704 (rank : 684)
Query Neighborhood Hits	557	Target Neighborhood Hits	950	Shared Neighborhood Hits	132
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

INSRR_MOUSE
θ value	θ > 10 (rank : 732)	NC score	0.061343 (rank : 680)
Query Neighborhood Hits	557	Target Neighborhood Hits	961	Shared Neighborhood Hits	138
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

KR105_HUMAN
θ value	θ > 10 (rank : 733)	NC score	0.356213 (rank : 206)
Query Neighborhood Hits	557	Target Neighborhood Hits	271	Shared Neighborhood Hits	164
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR111_HUMAN
θ value	θ > 10 (rank : 734)	NC score	0.079806 (rank : 558)
Query Neighborhood Hits	557	Target Neighborhood Hits	90	Shared Neighborhood Hits	52
SwissProt Accessions	Q8IUC1	Gene names	KRTAP11-1, KAP11.1, KRTAP11.1
Domain Architecture
Description	Keratin-associated protein 11-1 (High sulfur keratin-associated protein 11.1).

KR122_HUMAN
θ value	θ > 10 (rank : 735)	NC score	0.124598 (rank : 406)
Query Neighborhood Hits	557	Target Neighborhood Hits	97	Shared Neighborhood Hits	54
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

KR123_HUMAN
θ value	θ > 10 (rank : 736)	NC score	0.074462 (rank : 591)
Query Neighborhood Hits	557	Target Neighborhood Hits	75	Shared Neighborhood Hits	35
SwissProt Accessions	P60328	Gene names	KRTAP12-3, KAP12.3, KRTAP12.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-3 (Keratin-associated protein 12.3) (High sulfur keratin-associated protein 12.3).

KR124_HUMAN
θ value	θ > 10 (rank : 737)	NC score	0.112864 (rank : 434)
Query Neighborhood Hits	557	Target Neighborhood Hits	124	Shared Neighborhood Hits	71
SwissProt Accessions	P60329	Gene names	KRTAP12-4, KAP12.4, KRTAP12.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-4 (Keratin-associated protein 12.4) (High sulfur keratin-associated protein 12.4).

KR131_HUMAN
θ value	θ > 10 (rank : 738)	NC score	0.077484 (rank : 570)
Query Neighborhood Hits	557	Target Neighborhood Hits	123	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IUC0, Q3LI79	Gene names	KRTAP13-1, KAP13.1, KRTAP13.1
Domain Architecture
Description	Keratin-associated protein 13-1 (High sulfur keratin-associated protein 13.1).

KR132_HUMAN
θ value	θ > 10 (rank : 739)	NC score	0.059916 (rank : 691)
Query Neighborhood Hits	557	Target Neighborhood Hits	69	Shared Neighborhood Hits	36
SwissProt Accessions	Q52LG2	Gene names	KRTAP13-2, KAP13.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-2.

KR134_HUMAN
θ value	θ > 10 (rank : 740)	NC score	0.065832 (rank : 641)
Query Neighborhood Hits	557	Target Neighborhood Hits	81	Shared Neighborhood Hits	36
SwissProt Accessions	Q3LI77	Gene names	KRTAP13-4, KAP13.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-4.

KR171_HUMAN
θ value	θ > 10 (rank : 741)	NC score	0.463597 (rank : 138)
Query Neighborhood Hits	557	Target Neighborhood Hits	144	Shared Neighborhood Hits	108
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KR241_HUMAN
θ value	θ > 10 (rank : 742)	NC score	0.114682 (rank : 429)
Query Neighborhood Hits	557	Target Neighborhood Hits	71	Shared Neighborhood Hits	45
SwissProt Accessions	Q3LI83	Gene names	KRTAP24-1, KAP24.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 24-1.

KR261_HUMAN
θ value	θ > 10 (rank : 743)	NC score	0.052489 (rank : 788)
Query Neighborhood Hits	557	Target Neighborhood Hits	65	Shared Neighborhood Hits	31
SwissProt Accessions	Q6PEX3	Gene names	KRTAP26-1, KAP26.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 26-1.

KR410_HUMAN
θ value	θ > 10 (rank : 744)	NC score	0.210658 (rank : 313)
Query Neighborhood Hits	557	Target Neighborhood Hits	156	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

KR412_HUMAN
θ value	θ > 10 (rank : 745)	NC score	0.233450 (rank : 296)
Query Neighborhood Hits	557	Target Neighborhood Hits	178	Shared Neighborhood Hits	107
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR413_HUMAN
θ value	θ > 10 (rank : 746)	NC score	0.118004 (rank : 421)
Query Neighborhood Hits	557	Target Neighborhood Hits	112	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

KR414_HUMAN
θ value	θ > 10 (rank : 747)	NC score	0.273644 (rank : 263)
Query Neighborhood Hits	557	Target Neighborhood Hits	199	Shared Neighborhood Hits	116
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KRA13_HUMAN
θ value	θ > 10 (rank : 748)	NC score	0.291065 (rank : 245)
Query Neighborhood Hits	557	Target Neighborhood Hits	144	Shared Neighborhood Hits	94
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

KRA42_HUMAN
θ value	θ > 10 (rank : 749)	NC score	0.178711 (rank : 337)
Query Neighborhood Hits	557	Target Neighborhood Hits	149	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

KRA44_HUMAN
θ value	θ > 10 (rank : 750)	NC score	0.250376 (rank : 285)
Query Neighborhood Hits	557	Target Neighborhood Hits	162	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KRA45_HUMAN
θ value	θ > 10 (rank : 751)	NC score	0.277194 (rank : 259)
Query Neighborhood Hits	557	Target Neighborhood Hits	194	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

KRA47_HUMAN
θ value	θ > 10 (rank : 752)	NC score	0.303965 (rank : 237)
Query Neighborhood Hits	557	Target Neighborhood Hits	204	Shared Neighborhood Hits	117
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KRA63_HUMAN
θ value	θ > 10 (rank : 753)	NC score	0.056455 (rank : 733)
Query Neighborhood Hits	557	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q3LI67	Gene names	KRTAP6-3, KAP6.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 6-3.

KRA92_HUMAN
θ value	θ > 10 (rank : 754)	NC score	0.266709 (rank : 272)
Query Neighborhood Hits	557	Target Neighborhood Hits	198	Shared Neighborhood Hits	123
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA93_HUMAN
θ value	θ > 10 (rank : 755)	NC score	0.280839 (rank : 258)
Query Neighborhood Hits	557	Target Neighborhood Hits	203	Shared Neighborhood Hits	121
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA94_HUMAN
θ value	θ > 10 (rank : 756)	NC score	0.285467 (rank : 250)
Query Neighborhood Hits	557	Target Neighborhood Hits	204	Shared Neighborhood Hits	134
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KRA98_HUMAN
θ value	θ > 10 (rank : 757)	NC score	0.269974 (rank : 266)
Query Neighborhood Hits	557	Target Neighborhood Hits	185	Shared Neighborhood Hits	110
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA99_HUMAN
θ value	θ > 10 (rank : 758)	NC score	0.224469 (rank : 302)
Query Neighborhood Hits	557	Target Neighborhood Hits	173	Shared Neighborhood Hits	109
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

LCE1A_HUMAN
θ value	θ > 10 (rank : 759)	NC score	0.192676 (rank : 325)
Query Neighborhood Hits	557	Target Neighborhood Hits	47	Shared Neighborhood Hits	30
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LCE1B_HUMAN
θ value	θ > 10 (rank : 760)	NC score	0.249007 (rank : 286)
Query Neighborhood Hits	557	Target Neighborhood Hits	58	Shared Neighborhood Hits	40
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
θ value	θ > 10 (rank : 761)	NC score	0.266173 (rank : 273)
Query Neighborhood Hits	557	Target Neighborhood Hits	65	Shared Neighborhood Hits	41
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1D_HUMAN
θ value	θ > 10 (rank : 762)	NC score	0.202367 (rank : 317)
Query Neighborhood Hits	557	Target Neighborhood Hits	44	Shared Neighborhood Hits	29
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE1E_HUMAN
θ value	θ > 10 (rank : 763)	NC score	0.188519 (rank : 328)
Query Neighborhood Hits	557	Target Neighborhood Hits	53	Shared Neighborhood Hits	30
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LCE1F_HUMAN
θ value	θ > 10 (rank : 764)	NC score	0.192216 (rank : 326)
Query Neighborhood Hits	557	Target Neighborhood Hits	48	Shared Neighborhood Hits	29
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LCE2A_HUMAN
θ value	θ > 10 (rank : 765)	NC score	0.171886 (rank : 341)
Query Neighborhood Hits	557	Target Neighborhood Hits	50	Shared Neighborhood Hits	28
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

LCE2B_HUMAN
θ value	θ > 10 (rank : 766)	NC score	0.162153 (rank : 350)
Query Neighborhood Hits	557	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

LCE2C_HUMAN
θ value	θ > 10 (rank : 767)	NC score	0.163976 (rank : 346)
Query Neighborhood Hits	557	Target Neighborhood Hits	53	Shared Neighborhood Hits	30
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LCE2D_HUMAN
θ value	θ > 10 (rank : 768)	NC score	0.163287 (rank : 348)
Query Neighborhood Hits	557	Target Neighborhood Hits	50	Shared Neighborhood Hits	28
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

LCE3A_HUMAN
θ value	θ > 10 (rank : 769)	NC score	0.183437 (rank : 335)
Query Neighborhood Hits	557	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

LCE3B_HUMAN
θ value	θ > 10 (rank : 770)	NC score	0.080718 (rank : 552)
Query Neighborhood Hits	557	Target Neighborhood Hits	47	Shared Neighborhood Hits	29
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

LCE3C_HUMAN
θ value	θ > 10 (rank : 771)	NC score	0.052196 (rank : 793)
Query Neighborhood Hits	557	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	Q5T5A8	Gene names	LCE3C, LEP15, SPRL3A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A).

LCE3E_HUMAN
θ value	θ > 10 (rank : 772)	NC score	0.052734 (rank : 784)
Query Neighborhood Hits	557	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q5T5B0	Gene names	LCE3E, LEP17
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3E (Late envelope protein 17).

LCE4A_HUMAN
θ value	θ > 10 (rank : 773)	NC score	0.143950 (rank : 367)
Query Neighborhood Hits	557	Target Neighborhood Hits	26	Shared Neighborhood Hits	15
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

LCE5A_HUMAN
θ value	θ > 10 (rank : 774)	NC score	0.110921 (rank : 440)
Query Neighborhood Hits	557	Target Neighborhood Hits	43	Shared Neighborhood Hits	23
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

LDLR_HUMAN
θ value	θ > 10 (rank : 775)	NC score	0.310874 (rank : 232)
Query Neighborhood Hits	557	Target Neighborhood Hits	375	Shared Neighborhood Hits	223
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LDLR_MOUSE
θ value	θ > 10 (rank : 776)	NC score	0.296215 (rank : 242)
Query Neighborhood Hits	557	Target Neighborhood Hits	382	Shared Neighborhood Hits	216
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LEUK_HUMAN
θ value	θ > 10 (rank : 777)	NC score	0.055309 (rank : 747)
Query Neighborhood Hits	557	Target Neighborhood Hits	213	Shared Neighborhood Hits	49
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

LORI_MOUSE
θ value	θ > 10 (rank : 778)	NC score	0.134524 (rank : 383)
Query Neighborhood Hits	557	Target Neighborhood Hits	47	Shared Neighborhood Hits	20
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

LPHN1_HUMAN
θ value	θ > 10 (rank : 779)	NC score	0.056353 (rank : 735)
Query Neighborhood Hits	557	Target Neighborhood Hits	155	Shared Neighborhood Hits	24
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

LPHN2_HUMAN
θ value	θ > 10 (rank : 780)	NC score	0.054859 (rank : 755)
Query Neighborhood Hits	557	Target Neighborhood Hits	136	Shared Neighborhood Hits	14
SwissProt Accessions	O95490, O94882, Q5VX76, Q9UKY5, Q9UKY6	Gene names	LPHN2, KIAA0786, LEC1, LPHH1
Domain Architecture
Description	Latrophilin-2 precursor (Calcium-independent alpha-latrotoxin receptor 2) (Latrophilin homolog 1) (Lectomedin-1).

LPHN3_HUMAN
θ value	θ > 10 (rank : 781)	NC score	0.053889 (rank : 767)
Query Neighborhood Hits	557	Target Neighborhood Hits	139	Shared Neighborhood Hits	13
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

LRP10_HUMAN
θ value	θ > 10 (rank : 782)	NC score	0.138084 (rank : 378)
Query Neighborhood Hits	557	Target Neighborhood Hits	197	Shared Neighborhood Hits	79
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP10_MOUSE
θ value	θ > 10 (rank : 783)	NC score	0.134835 (rank : 382)
Query Neighborhood Hits	557	Target Neighborhood Hits	169	Shared Neighborhood Hits	73
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP12_HUMAN
θ value	θ > 10 (rank : 784)	NC score	0.085482 (rank : 525)
Query Neighborhood Hits	557	Target Neighborhood Hits	205	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
θ value	θ > 10 (rank : 785)	NC score	0.081687 (rank : 546)
Query Neighborhood Hits	557	Target Neighborhood Hits	180	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP3_HUMAN
θ value	θ > 10 (rank : 786)	NC score	0.118261 (rank : 420)
Query Neighborhood Hits	557	Target Neighborhood Hits	280	Shared Neighborhood Hits	108
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

LRP4_HUMAN
θ value	θ > 10 (rank : 787)	NC score	0.272832 (rank : 264)
Query Neighborhood Hits	557	Target Neighborhood Hits	355	Shared Neighborhood Hits	198
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP4_MOUSE
θ value	θ > 10 (rank : 788)	NC score	0.274332 (rank : 261)
Query Neighborhood Hits	557	Target Neighborhood Hits	351	Shared Neighborhood Hits	192
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LRP5_HUMAN
θ value	θ > 10 (rank : 789)	NC score	0.118705 (rank : 418)
Query Neighborhood Hits	557	Target Neighborhood Hits	224	Shared Neighborhood Hits	104
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LRP5_MOUSE
θ value	θ > 10 (rank : 790)	NC score	0.124837 (rank : 405)
Query Neighborhood Hits	557	Target Neighborhood Hits	236	Shared Neighborhood Hits	113
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

LRP6_HUMAN
θ value	θ > 10 (rank : 791)	NC score	0.127780 (rank : 398)
Query Neighborhood Hits	557	Target Neighborhood Hits	235	Shared Neighborhood Hits	106
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
θ value	θ > 10 (rank : 792)	NC score	0.125074 (rank : 403)
Query Neighborhood Hits	557	Target Neighborhood Hits	232	Shared Neighborhood Hits	104
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP8_HUMAN
θ value	θ > 10 (rank : 793)	NC score	0.281947 (rank : 256)
Query Neighborhood Hits	557	Target Neighborhood Hits	346	Shared Neighborhood Hits	195
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LYAM1_MOUSE
θ value	θ > 10 (rank : 794)	NC score	0.223381 (rank : 303)
Query Neighborhood Hits	557	Target Neighborhood Hits	332	Shared Neighborhood Hits	156
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

MADCA_HUMAN
θ value	θ > 10 (rank : 795)	NC score	0.070645 (rank : 611)
Query Neighborhood Hits	557	Target Neighborhood Hits	221	Shared Neighborhood Hits	64
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

MAP4_HUMAN
θ value	θ > 10 (rank : 796)	NC score	0.053767 (rank : 770)
Query Neighborhood Hits	557	Target Neighborhood Hits	428	Shared Neighborhood Hits	76
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MATN1_HUMAN
θ value	θ > 10 (rank : 797)	NC score	0.096575 (rank : 496)
Query Neighborhood Hits	557	Target Neighborhood Hits	191	Shared Neighborhood Hits	86
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN1_MOUSE
θ value	θ > 10 (rank : 798)	NC score	0.097089 (rank : 492)
Query Neighborhood Hits	557	Target Neighborhood Hits	186	Shared Neighborhood Hits	82
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN4_HUMAN
θ value	θ > 10 (rank : 799)	NC score	0.297959 (rank : 241)
Query Neighborhood Hits	557	Target Neighborhood Hits	287	Shared Neighborhood Hits	169
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MBD6_HUMAN
θ value	θ > 10 (rank : 800)	NC score	0.075977 (rank : 581)
Query Neighborhood Hits	557	Target Neighborhood Hits	349	Shared Neighborhood Hits	89
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MCSP_HUMAN
θ value	θ > 10 (rank : 801)	NC score	0.053658 (rank : 773)
Query Neighborhood Hits	557	Target Neighborhood Hits	48	Shared Neighborhood Hits	26
SwissProt Accessions	P49901, Q96A42	Gene names	SMCP, MCS, MCSP
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MCSP_MOUSE
θ value	θ > 10 (rank : 802)	NC score	0.134256 (rank : 386)
Query Neighborhood Hits	557	Target Neighborhood Hits	108	Shared Neighborhood Hits	50
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MEP1A_HUMAN
θ value	θ > 10 (rank : 803)	NC score	0.092701 (rank : 507)
Query Neighborhood Hits	557	Target Neighborhood Hits	162	Shared Neighborhood Hits	96
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

MEP1A_MOUSE
θ value	θ > 10 (rank : 804)	NC score	0.099855 (rank : 483)
Query Neighborhood Hits	557	Target Neighborhood Hits	166	Shared Neighborhood Hits	98
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

MEP1B_MOUSE
θ value	θ > 10 (rank : 805)	NC score	0.067788 (rank : 626)
Query Neighborhood Hits	557	Target Neighborhood Hits	127	Shared Neighborhood Hits	66
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

MFGM_HUMAN
θ value	θ > 10 (rank : 806)	NC score	0.115539 (rank : 426)
Query Neighborhood Hits	557	Target Neighborhood Hits	150	Shared Neighborhood Hits	93
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

MLL4_HUMAN
θ value	θ > 10 (rank : 807)	NC score	0.059543 (rank : 694)
Query Neighborhood Hits	557	Target Neighborhood Hits	722	Shared Neighborhood Hits	121
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MMRN1_HUMAN
θ value	θ > 10 (rank : 808)	NC score	0.151987 (rank : 361)
Query Neighborhood Hits	557	Target Neighborhood Hits	636	Shared Neighborhood Hits	124
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

MT1A_HUMAN
θ value	θ > 10 (rank : 809)	NC score	0.167386 (rank : 344)
Query Neighborhood Hits	557	Target Neighborhood Hits	74	Shared Neighborhood Hits	46
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

MT1B_HUMAN
θ value	θ > 10 (rank : 810)	NC score	0.138248 (rank : 377)
Query Neighborhood Hits	557	Target Neighborhood Hits	87	Shared Neighborhood Hits	50
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

MT1E_HUMAN
θ value	θ > 10 (rank : 811)	NC score	0.102437 (rank : 469)
Query Neighborhood Hits	557	Target Neighborhood Hits	75	Shared Neighborhood Hits	47
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

MT1F_HUMAN
θ value	θ > 10 (rank : 812)	NC score	0.084442 (rank : 529)
Query Neighborhood Hits	557	Target Neighborhood Hits	73	Shared Neighborhood Hits	42
SwissProt Accessions	P04733, Q9UI97	Gene names	MT1F
Domain Architecture	No domain graphic available
Description	Metallothionein-1F (MT-1F) (Metallothionein-IF) (MT-IF).

MT1G_HUMAN
θ value	θ > 10 (rank : 813)	NC score	0.100773 (rank : 478)
Query Neighborhood Hits	557	Target Neighborhood Hits	63	Shared Neighborhood Hits	30
SwissProt Accessions	P13640, P80296	Gene names	MT1G, MT1K, MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1G (MT-1G) (Metallothionein-IG) (MT-IG) (Metallothionein-1K) (MT-1K).

MT1H_HUMAN
θ value	θ > 10 (rank : 814)	NC score	0.138991 (rank : 376)
Query Neighborhood Hits	557	Target Neighborhood Hits	78	Shared Neighborhood Hits	48
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

MT1I_HUMAN
θ value	θ > 10 (rank : 815)	NC score	0.071824 (rank : 602)
Query Neighborhood Hits	557	Target Neighborhood Hits	64	Shared Neighborhood Hits	36
SwissProt Accessions	P80295	Gene names	MT1I
Domain Architecture	No domain graphic available
Description	Metallothionein-1I (MT-1I) (Metallothionein-II).

MT1L_HUMAN
θ value	θ > 10 (rank : 816)	NC score	0.100177 (rank : 481)
Query Neighborhood Hits	557	Target Neighborhood Hits	73	Shared Neighborhood Hits	37
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

MT1M_HUMAN
θ value	θ > 10 (rank : 817)	NC score	0.066804 (rank : 634)
Query Neighborhood Hits	557	Target Neighborhood Hits	72	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N339, Q8TDN3	Gene names	MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1M (MT-1M) (Metallothionein-IM) (MT-IM).

MT1X_HUMAN
θ value	θ > 10 (rank : 818)	NC score	0.185227 (rank : 332)
Query Neighborhood Hits	557	Target Neighborhood Hits	76	Shared Neighborhood Hits	50
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

MT1_MOUSE
θ value	θ > 10 (rank : 819)	NC score	0.133948 (rank : 387)
Query Neighborhood Hits	557	Target Neighborhood Hits	72	Shared Neighborhood Hits	38
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

MT2_HUMAN
θ value	θ > 10 (rank : 820)	NC score	0.078739 (rank : 562)
Query Neighborhood Hits	557	Target Neighborhood Hits	69	Shared Neighborhood Hits	41
SwissProt Accessions	P02795, Q14823, Q2HXR9, Q53XT9	Gene names	MT2A, CES1, MT2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II) (Metallothionein-2A).

MT2_MOUSE
θ value	θ > 10 (rank : 821)	NC score	0.148405 (rank : 362)
Query Neighborhood Hits	557	Target Neighborhood Hits	81	Shared Neighborhood Hits	48
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

MT3_HUMAN
θ value	θ > 10 (rank : 822)	NC score	0.222653 (rank : 304)
Query Neighborhood Hits	557	Target Neighborhood Hits	82	Shared Neighborhood Hits	49
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

MT3_MOUSE
θ value	θ > 10 (rank : 823)	NC score	0.286756 (rank : 249)
Query Neighborhood Hits	557	Target Neighborhood Hits	68	Shared Neighborhood Hits	46
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

MT4_HUMAN
θ value	θ > 10 (rank : 824)	NC score	0.153386 (rank : 359)
Query Neighborhood Hits	557	Target Neighborhood Hits	83	Shared Neighborhood Hits	50
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MT4_MOUSE
θ value	θ > 10 (rank : 825)	NC score	0.185040 (rank : 333)
Query Neighborhood Hits	557	Target Neighborhood Hits	102	Shared Neighborhood Hits	65
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MUC13_MOUSE
θ value	θ > 10 (rank : 826)	NC score	0.259583 (rank : 278)
Query Neighborhood Hits	557	Target Neighborhood Hits	447	Shared Neighborhood Hits	196
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

MUC7_HUMAN
θ value	θ > 10 (rank : 827)	NC score	0.133514 (rank : 389)
Query Neighborhood Hits	557	Target Neighborhood Hits	538	Shared Neighborhood Hits	137
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

MUCDL_MOUSE
θ value	θ > 10 (rank : 828)	NC score	0.080677 (rank : 553)
Query Neighborhood Hits	557	Target Neighborhood Hits	461	Shared Neighborhood Hits	85
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NELFA_MOUSE
θ value	θ > 10 (rank : 829)	NC score	0.062752 (rank : 669)
Query Neighborhood Hits	557	Target Neighborhood Hits	195	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

NEO1_HUMAN
θ value	θ > 10 (rank : 830)	NC score	0.057289 (rank : 725)
Query Neighborhood Hits	557	Target Neighborhood Hits	530	Shared Neighborhood Hits	55
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

NEO1_MOUSE
θ value	θ > 10 (rank : 831)	NC score	0.057201 (rank : 726)
Query Neighborhood Hits	557	Target Neighborhood Hits	523	Shared Neighborhood Hits	54
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

NID1_MOUSE
θ value	θ > 10 (rank : 832)	NC score	0.406617 (rank : 176)
Query Neighborhood Hits	557	Target Neighborhood Hits	335	Shared Neighborhood Hits	209
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NRG1_HUMAN
θ value	θ > 10 (rank : 833)	NC score	0.111331 (rank : 439)
Query Neighborhood Hits	557	Target Neighborhood Hits	285	Shared Neighborhood Hits	81
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

NRG2_HUMAN
θ value	θ > 10 (rank : 834)	NC score	0.095053 (rank : 500)
Query Neighborhood Hits	557	Target Neighborhood Hits	419	Shared Neighborhood Hits	96
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

NRG2_MOUSE
θ value	θ > 10 (rank : 835)	NC score	0.118968 (rank : 417)
Query Neighborhood Hits	557	Target Neighborhood Hits	392	Shared Neighborhood Hits	101
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

NRG3_HUMAN
θ value	θ > 10 (rank : 836)	NC score	0.063100 (rank : 662)
Query Neighborhood Hits	557	Target Neighborhood Hits	119	Shared Neighborhood Hits	60
SwissProt Accessions	P56975	Gene names	NRG3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

NRG3_MOUSE
θ value	θ > 10 (rank : 837)	NC score	0.068573 (rank : 621)
Query Neighborhood Hits	557	Target Neighborhood Hits	132	Shared Neighborhood Hits	70
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

NRG4_HUMAN
θ value	θ > 10 (rank : 838)	NC score	0.101442 (rank : 475)
Query Neighborhood Hits	557	Target Neighborhood Hits	85	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRG4_MOUSE
θ value	θ > 10 (rank : 839)	NC score	0.093346 (rank : 506)
Query Neighborhood Hits	557	Target Neighborhood Hits	79	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRX1A_HUMAN
θ value	θ > 10 (rank : 840)	NC score	0.289327 (rank : 246)
Query Neighborhood Hits	557	Target Neighborhood Hits	170	Shared Neighborhood Hits	108
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
θ value	θ > 10 (rank : 841)	NC score	0.287473 (rank : 247)
Query Neighborhood Hits	557	Target Neighborhood Hits	164	Shared Neighborhood Hits	107
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1B_HUMAN
θ value	θ > 10 (rank : 842)	NC score	0.063550 (rank : 655)
Query Neighborhood Hits	557	Target Neighborhood Hits	37	Shared Neighborhood Hits	18
SwissProt Accessions	P58400	Gene names	NRXN1
Domain Architecture	No domain graphic available
Description	Neurexin-1-beta precursor (Neurexin I-beta).

NRX3A_HUMAN
θ value	θ > 10 (rank : 843)	NC score	0.277182 (rank : 260)
Query Neighborhood Hits	557	Target Neighborhood Hits	164	Shared Neighborhood Hits	104
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

NRX3B_HUMAN
θ value	θ > 10 (rank : 844)	NC score	0.068075 (rank : 624)
Query Neighborhood Hits	557	Target Neighborhood Hits	36	Shared Neighborhood Hits	18
SwissProt Accessions	Q9HDB5	Gene names	NRXN3, KIAA0743
Domain Architecture	No domain graphic available
Description	Neurexin-3-beta precursor (Neurexin III-beta).

NU214_HUMAN
θ value	θ > 10 (rank : 845)	NC score	0.066559 (rank : 635)
Query Neighborhood Hits	557	Target Neighborhood Hits	657	Shared Neighborhood Hits	96
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

NUMA1_HUMAN
θ value	θ > 10 (rank : 846)	NC score	0.054178 (rank : 762)
Query Neighborhood Hits	557	Target Neighborhood Hits	1523	Shared Neighborhood Hits	52
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

ODFP_MOUSE
θ value	θ > 10 (rank : 847)	NC score	0.103988 (rank : 461)
Query Neighborhood Hits	557	Target Neighborhood Hits	75	Shared Neighborhood Hits	45
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

PAPPA_HUMAN
θ value	θ > 10 (rank : 848)	NC score	0.073513 (rank : 595)
Query Neighborhood Hits	557	Target Neighborhood Hits	161	Shared Neighborhood Hits	69
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PAPPA_MOUSE
θ value	θ > 10 (rank : 849)	NC score	0.074176 (rank : 594)
Query Neighborhood Hits	557	Target Neighborhood Hits	153	Shared Neighborhood Hits	67
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PARM1_HUMAN
θ value	θ > 10 (rank : 850)	NC score	0.053414 (rank : 777)
Query Neighborhood Hits	557	Target Neighborhood Hits	86	Shared Neighborhood Hits	32
SwissProt Accessions	Q6UWI2, Q96DV8, Q9Y4S1	Gene names	ames=UNQ1879/PRO4322
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

PCD15_HUMAN
θ value	θ > 10 (rank : 851)	NC score	0.053853 (rank : 768)
Query Neighborhood Hits	557	Target Neighborhood Hits	289	Shared Neighborhood Hits	51
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

PCD15_MOUSE
θ value	θ > 10 (rank : 852)	NC score	0.055616 (rank : 742)
Query Neighborhood Hits	557	Target Neighborhood Hits	262	Shared Neighborhood Hits	54
SwissProt Accessions	Q99PJ1	Gene names	Pcdh15
Domain Architecture
Description	Protocadherin-15 precursor.

PCLO_MOUSE
θ value	θ > 10 (rank : 853)	NC score	0.055775 (rank : 740)
Query Neighborhood Hits	557	Target Neighborhood Hits	2275	Shared Neighborhood Hits	164
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PCSK4_HUMAN
θ value	θ > 10 (rank : 854)	NC score	0.051192 (rank : 803)
Query Neighborhood Hits	557	Target Neighborhood Hits	32	Shared Neighborhood Hits	15
SwissProt Accessions	Q6UW60, Q8IY88, Q9UF79	Gene names	PCSK4, PC4
Domain Architecture	No domain graphic available
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (Proprotein convertase PC4).

PERT_HUMAN
θ value	θ > 10 (rank : 855)	NC score	0.140507 (rank : 373)
Query Neighborhood Hits	557	Target Neighborhood Hits	221	Shared Neighborhood Hits	114
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PERT_MOUSE
θ value	θ > 10 (rank : 856)	NC score	0.125986 (rank : 401)
Query Neighborhood Hits	557	Target Neighborhood Hits	221	Shared Neighborhood Hits	111
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PGCA_MOUSE
θ value	θ > 10 (rank : 857)	NC score	0.057665 (rank : 720)
Query Neighborhood Hits	557	Target Neighborhood Hits	643	Shared Neighborhood Hits	65
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

PGCB_HUMAN
θ value	θ > 10 (rank : 858)	NC score	0.184594 (rank : 334)
Query Neighborhood Hits	557	Target Neighborhood Hits	478	Shared Neighborhood Hits	171
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

PGCB_MOUSE
θ value	θ > 10 (rank : 859)	NC score	0.190040 (rank : 327)
Query Neighborhood Hits	557	Target Neighborhood Hits	459	Shared Neighborhood Hits	161
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

PGH1_HUMAN
θ value	θ > 10 (rank : 860)	NC score	0.079450 (rank : 559)
Query Neighborhood Hits	557	Target Neighborhood Hits	91	Shared Neighborhood Hits	54
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

PGH1_MOUSE
θ value	θ > 10 (rank : 861)	NC score	0.096180 (rank : 497)
Query Neighborhood Hits	557	Target Neighborhood Hits	100	Shared Neighborhood Hits	61
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

PGH2_HUMAN
θ value	θ > 10 (rank : 862)	NC score	0.099750 (rank : 485)
Query Neighborhood Hits	557	Target Neighborhood Hits	103	Shared Neighborhood Hits	64
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

PGH2_MOUSE
θ value	θ > 10 (rank : 863)	NC score	0.113925 (rank : 431)
Query Neighborhood Hits	557	Target Neighborhood Hits	113	Shared Neighborhood Hits	76
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

PHXR5_MOUSE
θ value	θ > 10 (rank : 864)	NC score	0.102081 (rank : 471)
Query Neighborhood Hits	557	Target Neighborhood Hits	102	Shared Neighborhood Hits	50
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

PI5PA_MOUSE
θ value	θ > 10 (rank : 865)	NC score	0.050357 (rank : 817)
Query Neighborhood Hits	557	Target Neighborhood Hits	331	Shared Neighborhood Hits	76
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PO121_HUMAN
θ value	θ > 10 (rank : 866)	NC score	0.073319 (rank : 597)
Query Neighborhood Hits	557	Target Neighborhood Hits	344	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PO121_MOUSE
θ value	θ > 10 (rank : 867)	NC score	0.053970 (rank : 765)
Query Neighborhood Hits	557	Target Neighborhood Hits	345	Shared Neighborhood Hits	75
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

PRB3_HUMAN
θ value	θ > 10 (rank : 868)	NC score	0.079064 (rank : 561)
Query Neighborhood Hits	557	Target Neighborhood Hits	318	Shared Neighborhood Hits	65
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 869)	NC score	0.070929 (rank : 609)
Query Neighborhood Hits	557	Target Neighborhood Hits	330	Shared Neighborhood Hits	65
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRG4_MOUSE
θ value	θ > 10 (rank : 870)	NC score	0.082365 (rank : 540)
Query Neighborhood Hits	557	Target Neighborhood Hits	624	Shared Neighborhood Hits	115
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PROC_HUMAN
θ value	θ > 10 (rank : 871)	NC score	0.132833 (rank : 390)
Query Neighborhood Hits	557	Target Neighborhood Hits	406	Shared Neighborhood Hits	174
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PRP1_HUMAN
θ value	θ > 10 (rank : 872)	NC score	0.081085 (rank : 549)
Query Neighborhood Hits	557	Target Neighborhood Hits	385	Shared Neighborhood Hits	79
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 873)	NC score	0.108668 (rank : 445)
Query Neighborhood Hits	557	Target Neighborhood Hits	347	Shared Neighborhood Hits	82
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRR12_HUMAN
θ value	θ > 10 (rank : 874)	NC score	0.103677 (rank : 462)
Query Neighborhood Hits	557	Target Neighborhood Hits	460	Shared Neighborhood Hits	105
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PRR13_HUMAN
θ value	θ > 10 (rank : 875)	NC score	0.061692 (rank : 677)
Query Neighborhood Hits	557	Target Neighborhood Hits	105	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

RAPH1_HUMAN
θ value	θ > 10 (rank : 876)	NC score	0.074321 (rank : 593)
Query Neighborhood Hits	557	Target Neighborhood Hits	593	Shared Neighborhood Hits	120
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RECK_HUMAN
θ value	θ > 10 (rank : 877)	NC score	0.143968 (rank : 366)
Query Neighborhood Hits	557	Target Neighborhood Hits	189	Shared Neighborhood Hits	97
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

RECK_MOUSE
θ value	θ > 10 (rank : 878)	NC score	0.123228 (rank : 408)
Query Neighborhood Hits	557	Target Neighborhood Hits	158	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

RELN_HUMAN
θ value	θ > 10 (rank : 879)	NC score	0.174262 (rank : 339)
Query Neighborhood Hits	557	Target Neighborhood Hits	233	Shared Neighborhood Hits	152
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

RELN_MOUSE
θ value	θ > 10 (rank : 880)	NC score	0.178492 (rank : 338)
Query Neighborhood Hits	557	Target Neighborhood Hits	235	Shared Neighborhood Hits	153
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

RERE_HUMAN
θ value	θ > 10 (rank : 881)	NC score	0.064825 (rank : 648)
Query Neighborhood Hits	557	Target Neighborhood Hits	779	Shared Neighborhood Hits	127
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RSPO1_HUMAN
θ value	θ > 10 (rank : 882)	NC score	0.076531 (rank : 577)
Query Neighborhood Hits	557	Target Neighborhood Hits	101	Shared Neighborhood Hits	49
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

RSPO1_MOUSE
θ value	θ > 10 (rank : 883)	NC score	0.058104 (rank : 713)
Query Neighborhood Hits	557	Target Neighborhood Hits	85	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

RSPO4_HUMAN
θ value	θ > 10 (rank : 884)	NC score	0.119096 (rank : 415)
Query Neighborhood Hits	557	Target Neighborhood Hits	110	Shared Neighborhood Hits	66
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

RSPO4_MOUSE
θ value	θ > 10 (rank : 885)	NC score	0.114930 (rank : 427)
Query Neighborhood Hits	557	Target Neighborhood Hits	110	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

SDC3_HUMAN
θ value	θ > 10 (rank : 886)	NC score	0.057518 (rank : 722)
Query Neighborhood Hits	557	Target Neighborhood Hits	103	Shared Neighborhood Hits	48
SwissProt Accessions	O75056, Q5T1Z6, Q5T1Z7, Q96CT3, Q96PR8	Gene names	SDC3, KIAA0468
Domain Architecture
Description	Syndecan-3 (SYND3).

SDC3_MOUSE
θ value	θ > 10 (rank : 887)	NC score	0.054442 (rank : 760)
Query Neighborhood Hits	557	Target Neighborhood Hits	107	Shared Neighborhood Hits	49
SwissProt Accessions	Q64519, Q3UDD9, Q6ZQA4, Q7TQD4	Gene names	Sdc3, Kiaa0468
Domain Architecture
Description	Syndecan-3 precursor (SYND3).

SDK1_HUMAN
θ value	θ > 10 (rank : 888)	NC score	0.057713 (rank : 718)
Query Neighborhood Hits	557	Target Neighborhood Hits	511	Shared Neighborhood Hits	62
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK1_MOUSE
θ value	θ > 10 (rank : 889)	NC score	0.057668 (rank : 719)
Query Neighborhood Hits	557	Target Neighborhood Hits	495	Shared Neighborhood Hits	60
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK2_HUMAN
θ value	θ > 10 (rank : 890)	NC score	0.057726 (rank : 717)
Query Neighborhood Hits	557	Target Neighborhood Hits	495	Shared Neighborhood Hits	51
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SDK2_MOUSE
θ value	θ > 10 (rank : 891)	NC score	0.058832 (rank : 701)
Query Neighborhood Hits	557	Target Neighborhood Hits	480	Shared Neighborhood Hits	56
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SELPL_HUMAN
θ value	θ > 10 (rank : 892)	NC score	0.065391 (rank : 644)
Query Neighborhood Hits	557	Target Neighborhood Hits	68	Shared Neighborhood Hits	34
SwissProt Accessions	Q14242, Q12775	Gene names	SELPLG
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand) (CD162 antigen).

SELV_HUMAN
θ value	θ > 10 (rank : 893)	NC score	0.063356 (rank : 658)
Query Neighborhood Hits	557	Target Neighborhood Hits	118	Shared Neighborhood Hits	46
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

SF01_HUMAN
θ value	θ > 10 (rank : 894)	NC score	0.051526 (rank : 800)
Query Neighborhood Hits	557	Target Neighborhood Hits	287	Shared Neighborhood Hits	70
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SF3A2_HUMAN
θ value	θ > 10 (rank : 895)	NC score	0.079850 (rank : 557)
Query Neighborhood Hits	557	Target Neighborhood Hits	263	Shared Neighborhood Hits	65
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SF3A2_MOUSE
θ value	θ > 10 (rank : 896)	NC score	0.086275 (rank : 522)
Query Neighborhood Hits	557	Target Neighborhood Hits	247	Shared Neighborhood Hits	68
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SFPQ_MOUSE
θ value	θ > 10 (rank : 897)	NC score	0.053060 (rank : 779)
Query Neighborhood Hits	557	Target Neighborhood Hits	958	Shared Neighborhood Hits	112
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SHAN1_HUMAN
θ value	θ > 10 (rank : 898)	NC score	0.050430 (rank : 815)
Query Neighborhood Hits	557	Target Neighborhood Hits	1041	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SHBG_HUMAN
θ value	θ > 10 (rank : 899)	NC score	0.165773 (rank : 345)
Query Neighborhood Hits	557	Target Neighborhood Hits	45	Shared Neighborhood Hits	25
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

SHBG_MOUSE
θ value	θ > 10 (rank : 900)	NC score	0.158564 (rank : 355)
Query Neighborhood Hits	557	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	P97497	Gene names	Shbg
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP).

SMDF_HUMAN
θ value	θ > 10 (rank : 901)	NC score	0.118397 (rank : 419)
Query Neighborhood Hits	557	Target Neighborhood Hits	117	Shared Neighborhood Hits	65
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

SMR1_MOUSE
θ value	θ > 10 (rank : 902)	NC score	0.065978 (rank : 640)
Query Neighborhood Hits	557	Target Neighborhood Hits	103	Shared Neighborhood Hits	42
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

SPR2B_MOUSE
θ value	θ > 10 (rank : 903)	NC score	0.064592 (rank : 650)
Query Neighborhood Hits	557	Target Neighborhood Hits	51	Shared Neighborhood Hits	25
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

SPR2D_HUMAN
θ value	θ > 10 (rank : 904)	NC score	0.052029 (rank : 797)
Query Neighborhood Hits	557	Target Neighborhood Hits	30	Shared Neighborhood Hits	16
SwissProt Accessions	P22532, Q5T523, Q96RM3	Gene names	SPRR2D
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D (SPR-2D) (Small proline-rich protein II) (SPR-II).

SPR2D_MOUSE
θ value	θ > 10 (rank : 905)	NC score	0.086310 (rank : 521)
Query Neighborhood Hits	557	Target Neighborhood Hits	61	Shared Neighborhood Hits	29
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

SPR2E_HUMAN
θ value	θ > 10 (rank : 906)	NC score	0.055198 (rank : 750)
Query Neighborhood Hits	557	Target Neighborhood Hits	32	Shared Neighborhood Hits	17
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

SPR2E_MOUSE
θ value	θ > 10 (rank : 907)	NC score	0.051192 (rank : 802)
Query Neighborhood Hits	557	Target Neighborhood Hits	45	Shared Neighborhood Hits	17
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

SPR2F_HUMAN
θ value	θ > 10 (rank : 908)	NC score	0.071786 (rank : 603)
Query Neighborhood Hits	557	Target Neighborhood Hits	33	Shared Neighborhood Hits	16
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

SPR2G_MOUSE
θ value	θ > 10 (rank : 909)	NC score	0.077604 (rank : 569)
Query Neighborhood Hits	557	Target Neighborhood Hits	53	Shared Neighborhood Hits	27
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

SPR2H_MOUSE
θ value	θ > 10 (rank : 910)	NC score	0.091600 (rank : 510)
Query Neighborhood Hits	557	Target Neighborhood Hits	82	Shared Neighborhood Hits	40
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

SPR2I_MOUSE
θ value	θ > 10 (rank : 911)	NC score	0.056342 (rank : 736)
Query Neighborhood Hits	557	Target Neighborhood Hits	45	Shared Neighborhood Hits	21
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

SRRM1_HUMAN
θ value	θ > 10 (rank : 912)	NC score	0.067946 (rank : 625)
Query Neighborhood Hits	557	Target Neighborhood Hits	690	Shared Neighborhood Hits	94
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
θ value	θ > 10 (rank : 913)	NC score	0.071383 (rank : 607)
Query Neighborhood Hits	557	Target Neighborhood Hits	966	Shared Neighborhood Hits	114
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM2_HUMAN
θ value	θ > 10 (rank : 914)	NC score	0.055501 (rank : 744)
Query Neighborhood Hits	557	Target Neighborhood Hits	1296	Shared Neighborhood Hits	130
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

T22D2_HUMAN
θ value	θ > 10 (rank : 915)	NC score	0.055034 (rank : 752)
Query Neighborhood Hits	557	Target Neighborhood Hits	250	Shared Neighborhood Hits	65
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

TAF4_HUMAN
θ value	θ > 10 (rank : 916)	NC score	0.082355 (rank : 541)
Query Neighborhood Hits	557	Target Neighborhood Hits	687	Shared Neighborhood Hits	114
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TDGF1_HUMAN
θ value	θ > 10 (rank : 917)	NC score	0.201397 (rank : 318)
Query Neighborhood Hits	557	Target Neighborhood Hits	132	Shared Neighborhood Hits	102
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

TDGF1_MOUSE
θ value	θ > 10 (rank : 918)	NC score	0.251482 (rank : 284)
Query Neighborhood Hits	557	Target Neighborhood Hits	146	Shared Neighborhood Hits	115
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

TDGF2_HUMAN
θ value	θ > 10 (rank : 919)	NC score	0.196935 (rank : 322)
Query Neighborhood Hits	557	Target Neighborhood Hits	131	Shared Neighborhood Hits	99
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

TECTA_HUMAN
θ value	θ > 10 (rank : 920)	NC score	0.111463 (rank : 438)
Query Neighborhood Hits	557	Target Neighborhood Hits	239	Shared Neighborhood Hits	128
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

TECTA_MOUSE
θ value	θ > 10 (rank : 921)	NC score	0.125393 (rank : 402)
Query Neighborhood Hits	557	Target Neighborhood Hits	244	Shared Neighborhood Hits	142
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TEFF2_HUMAN
θ value	θ > 10 (rank : 922)	NC score	0.205284 (rank : 316)
Query Neighborhood Hits	557	Target Neighborhood Hits	211	Shared Neighborhood Hits	115
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
θ value	θ > 10 (rank : 923)	NC score	0.207830 (rank : 315)
Query Neighborhood Hits	557	Target Neighborhood Hits	214	Shared Neighborhood Hits	114
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TENN_HUMAN
θ value	θ > 10 (rank : 924)	NC score	0.322437 (rank : 226)
Query Neighborhood Hits	557	Target Neighborhood Hits	453	Shared Neighborhood Hits	240
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TGFA_HUMAN
θ value	θ > 10 (rank : 925)	NC score	0.052781 (rank : 783)
Query Neighborhood Hits	557	Target Neighborhood Hits	61	Shared Neighborhood Hits	38
SwissProt Accessions	P01135, Q15577	Gene names	TGFA
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

TLL1_HUMAN
θ value	θ > 10 (rank : 926)	NC score	0.103174 (rank : 464)
Query Neighborhood Hits	557	Target Neighborhood Hits	236	Shared Neighborhood Hits	108
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL1_MOUSE
θ value	θ > 10 (rank : 927)	NC score	0.107009 (rank : 451)
Query Neighborhood Hits	557	Target Neighborhood Hits	237	Shared Neighborhood Hits	112
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL2_HUMAN
θ value	θ > 10 (rank : 928)	NC score	0.103090 (rank : 466)
Query Neighborhood Hits	557	Target Neighborhood Hits	241	Shared Neighborhood Hits	116
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL2_MOUSE
θ value	θ > 10 (rank : 929)	NC score	0.099017 (rank : 486)
Query Neighborhood Hits	557	Target Neighborhood Hits	240	Shared Neighborhood Hits	111
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TMPS6_HUMAN
θ value	θ > 10 (rank : 930)	NC score	0.055157 (rank : 751)
Query Neighborhood Hits	557	Target Neighborhood Hits	338	Shared Neighborhood Hits	94
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS6_MOUSE
θ value	θ > 10 (rank : 931)	NC score	0.050809 (rank : 810)
Query Neighborhood Hits	557	Target Neighborhood Hits	341	Shared Neighborhood Hits	92
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TNR11_HUMAN
θ value	θ > 10 (rank : 932)	NC score	0.128293 (rank : 397)
Query Neighborhood Hits	557	Target Neighborhood Hits	135	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR11_MOUSE
θ value	θ > 10 (rank : 933)	NC score	0.110055 (rank : 442)
Query Neighborhood Hits	557	Target Neighborhood Hits	121	Shared Neighborhood Hits	72
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR18_HUMAN
θ value	θ > 10 (rank : 934)	NC score	0.067659 (rank : 627)
Query Neighborhood Hits	557	Target Neighborhood Hits	55	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TNR19_HUMAN
θ value	θ > 10 (rank : 935)	NC score	0.116066 (rank : 423)
Query Neighborhood Hits	557	Target Neighborhood Hits	89	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR19_MOUSE
θ value	θ > 10 (rank : 936)	NC score	0.137181 (rank : 380)
Query Neighborhood Hits	557	Target Neighborhood Hits	100	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR1A_HUMAN
θ value	θ > 10 (rank : 937)	NC score	0.082729 (rank : 539)
Query Neighborhood Hits	557	Target Neighborhood Hits	121	Shared Neighborhood Hits	60
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TNR1B_MOUSE
θ value	θ > 10 (rank : 938)	NC score	0.075061 (rank : 587)
Query Neighborhood Hits	557	Target Neighborhood Hits	123	Shared Neighborhood Hits	59
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TNR21_HUMAN
θ value	θ > 10 (rank : 939)	NC score	0.062739 (rank : 670)
Query Neighborhood Hits	557	Target Neighborhood Hits	90	Shared Neighborhood Hits	51
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR21_MOUSE
θ value	θ > 10 (rank : 940)	NC score	0.069916 (rank : 616)
Query Neighborhood Hits	557	Target Neighborhood Hits	108	Shared Neighborhood Hits	56
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR25_HUMAN
θ value	θ > 10 (rank : 941)	NC score	0.228993 (rank : 300)
Query Neighborhood Hits	557	Target Neighborhood Hits	172	Shared Neighborhood Hits	99
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TNR27_HUMAN
θ value	θ > 10 (rank : 942)	NC score	0.055353 (rank : 746)
Query Neighborhood Hits	557	Target Neighborhood Hits	69	Shared Neighborhood Hits	38
SwissProt Accessions	Q9HAV5, Q6UWM2, Q8IZA6	Gene names	EDA2R, TNFRSF27, XEDAR
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TNR27_MOUSE
θ value	θ > 10 (rank : 943)	NC score	0.063180 (rank : 661)
Query Neighborhood Hits	557	Target Neighborhood Hits	61	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BX35, Q8BM50	Gene names	Eda2r, Tnfrsf27, Xedar
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TNR3_MOUSE
θ value	θ > 10 (rank : 944)	NC score	0.154944 (rank : 358)
Query Neighborhood Hits	557	Target Neighborhood Hits	113	Shared Neighborhood Hits	76
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR4_HUMAN
θ value	θ > 10 (rank : 945)	NC score	0.244618 (rank : 287)
Query Neighborhood Hits	557	Target Neighborhood Hits	152	Shared Neighborhood Hits	92
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR5_MOUSE
θ value	θ > 10 (rank : 946)	NC score	0.142025 (rank : 371)
Query Neighborhood Hits	557	Target Neighborhood Hits	131	Shared Neighborhood Hits	84
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TNR6B_HUMAN
θ value	θ > 10 (rank : 947)	NC score	0.111967 (rank : 436)
Query Neighborhood Hits	557	Target Neighborhood Hits	103	Shared Neighborhood Hits	65
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TNR6_HUMAN
θ value	θ > 10 (rank : 948)	NC score	0.097418 (rank : 490)
Query Neighborhood Hits	557	Target Neighborhood Hits	95	Shared Neighborhood Hits	58
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR7_MOUSE
θ value	θ > 10 (rank : 949)	NC score	0.137829 (rank : 379)
Query Neighborhood Hits	557	Target Neighborhood Hits	112	Shared Neighborhood Hits	61
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

TNR8_MOUSE
θ value	θ > 10 (rank : 950)	NC score	0.135285 (rank : 381)
Query Neighborhood Hits	557	Target Neighborhood Hits	208	Shared Neighborhood Hits	93
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TNR9_HUMAN
θ value	θ > 10 (rank : 951)	NC score	0.139860 (rank : 374)
Query Neighborhood Hits	557	Target Neighborhood Hits	166	Shared Neighborhood Hits	103
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TPA_HUMAN
θ value	θ > 10 (rank : 952)	NC score	0.075396 (rank : 584)
Query Neighborhood Hits	557	Target Neighborhood Hits	324	Shared Neighborhood Hits	123
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TPA_MOUSE
θ value	θ > 10 (rank : 953)	NC score	0.079266 (rank : 560)
Query Neighborhood Hits	557	Target Neighborhood Hits	335	Shared Neighborhood Hits	126
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TR10A_HUMAN
θ value	θ > 10 (rank : 954)	NC score	0.062737 (rank : 671)
Query Neighborhood Hits	557	Target Neighborhood Hits	82	Shared Neighborhood Hits	48
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

TR10B_HUMAN
θ value	θ > 10 (rank : 955)	NC score	0.052814 (rank : 781)
Query Neighborhood Hits	557	Target Neighborhood Hits	71	Shared Neighborhood Hits	42
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

TR10B_MOUSE
θ value	θ > 10 (rank : 956)	NC score	0.089278 (rank : 515)
Query Neighborhood Hits	557	Target Neighborhood Hits	76	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TR11B_MOUSE
θ value	θ > 10 (rank : 957)	NC score	0.083807 (rank : 532)
Query Neighborhood Hits	557	Target Neighborhood Hits	95	Shared Neighborhood Hits	51
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TR19L_HUMAN
θ value	θ > 10 (rank : 958)	NC score	0.099013 (rank : 487)
Query Neighborhood Hits	557	Target Neighborhood Hits	99	Shared Neighborhood Hits	48
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

TRBM_MOUSE
θ value	θ > 10 (rank : 959)	NC score	0.412768 (rank : 174)
Query Neighborhood Hits	557	Target Neighborhood Hits	361	Shared Neighborhood Hits	219
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TSG6_HUMAN
θ value	θ > 10 (rank : 960)	NC score	0.058954 (rank : 700)
Query Neighborhood Hits	557	Target Neighborhood Hits	91	Shared Neighborhood Hits	18
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
θ value	θ > 10 (rank : 961)	NC score	0.059137 (rank : 696)
Query Neighborhood Hits	557	Target Neighborhood Hits	91	Shared Neighborhood Hits	17
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

UROL1_HUMAN
θ value	θ > 10 (rank : 962)	NC score	0.106974 (rank : 452)
Query Neighborhood Hits	557	Target Neighborhood Hits	213	Shared Neighborhood Hits	102
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

UROL1_MOUSE
θ value	θ > 10 (rank : 963)	NC score	0.120961 (rank : 411)
Query Neighborhood Hits	557	Target Neighborhood Hits	235	Shared Neighborhood Hits	113
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

UROM_HUMAN
θ value	θ > 10 (rank : 964)	NC score	0.404562 (rank : 178)
Query Neighborhood Hits	557	Target Neighborhood Hits	284	Shared Neighborhood Hits	200
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_MOUSE
θ value	θ > 10 (rank : 965)	NC score	0.392571 (rank : 183)
Query Neighborhood Hits	557	Target Neighborhood Hits	276	Shared Neighborhood Hits	200
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

VASN_HUMAN
θ value	θ > 10 (rank : 966)	NC score	0.108132 (rank : 447)
Query Neighborhood Hits	557	Target Neighborhood Hits	449	Shared Neighborhood Hits	120
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

VEGFC_MOUSE
θ value	θ > 10 (rank : 967)	NC score	0.126886 (rank : 400)
Query Neighborhood Hits	557	Target Neighborhood Hits	119	Shared Neighborhood Hits	80
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

VLDLR_HUMAN
θ value	θ > 10 (rank : 968)	NC score	0.322824 (rank : 224)
Query Neighborhood Hits	557	Target Neighborhood Hits	383	Shared Neighborhood Hits	218
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
θ value	θ > 10 (rank : 969)	NC score	0.319700 (rank : 228)
Query Neighborhood Hits	557	Target Neighborhood Hits	360	Shared Neighborhood Hits	204
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VWF_HUMAN
θ value	θ > 10 (rank : 970)	NC score	0.235660 (rank : 293)
Query Neighborhood Hits	557	Target Neighborhood Hits	396	Shared Neighborhood Hits	195
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

WASF1_HUMAN
θ value	θ > 10 (rank : 971)	NC score	0.057500 (rank : 723)
Query Neighborhood Hits	557	Target Neighborhood Hits	260	Shared Neighborhood Hits	85
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

WASF1_MOUSE
θ value	θ > 10 (rank : 972)	NC score	0.058719 (rank : 705)
Query Neighborhood Hits	557	Target Neighborhood Hits	261	Shared Neighborhood Hits	83
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

WASF2_HUMAN
θ value	θ > 10 (rank : 973)	NC score	0.058748 (rank : 703)
Query Neighborhood Hits	557	Target Neighborhood Hits	280	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

WASF2_MOUSE
θ value	θ > 10 (rank : 974)	NC score	0.061018 (rank : 683)
Query Neighborhood Hits	557	Target Neighborhood Hits	315	Shared Neighborhood Hits	92
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

WASF4_HUMAN
θ value	θ > 10 (rank : 975)	NC score	0.059968 (rank : 689)
Query Neighborhood Hits	557	Target Neighborhood Hits	282	Shared Neighborhood Hits	83
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

WASIP_HUMAN
θ value	θ > 10 (rank : 976)	NC score	0.083563 (rank : 533)
Query Neighborhood Hits	557	Target Neighborhood Hits	458	Shared Neighborhood Hits	98
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WASIP_MOUSE
θ value	θ > 10 (rank : 977)	NC score	0.083234 (rank : 537)
Query Neighborhood Hits	557	Target Neighborhood Hits	392	Shared Neighborhood Hits	96
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

WASL_HUMAN
θ value	θ > 10 (rank : 978)	NC score	0.066352 (rank : 638)
Query Neighborhood Hits	557	Target Neighborhood Hits	312	Shared Neighborhood Hits	82
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASL_MOUSE
θ value	θ > 10 (rank : 979)	NC score	0.066266 (rank : 639)
Query Neighborhood Hits	557	Target Neighborhood Hits	339	Shared Neighborhood Hits	83
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASP_MOUSE
θ value	θ > 10 (rank : 980)	NC score	0.053746 (rank : 771)
Query Neighborhood Hits	557	Target Neighborhood Hits	223	Shared Neighborhood Hits	59
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

WBP11_HUMAN
θ value	θ > 10 (rank : 981)	NC score	0.062409 (rank : 673)
Query Neighborhood Hits	557	Target Neighborhood Hits	354	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
θ value	θ > 10 (rank : 982)	NC score	0.061052 (rank : 682)
Query Neighborhood Hits	557	Target Neighborhood Hits	362	Shared Neighborhood Hits	73
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

WBS14_HUMAN
θ value	θ > 10 (rank : 983)	NC score	0.055250 (rank : 748)
Query Neighborhood Hits	557	Target Neighborhood Hits	273	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

WFDC3_HUMAN
θ value	θ > 10 (rank : 984)	NC score	0.106348 (rank : 454)
Query Neighborhood Hits	557	Target Neighborhood Hits	138	Shared Neighborhood Hits	63
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

WIRE_HUMAN
θ value	θ > 10 (rank : 985)	NC score	0.071509 (rank : 606)
Query Neighborhood Hits	557	Target Neighborhood Hits	329	Shared Neighborhood Hits	82
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

WIRE_MOUSE
θ value	θ > 10 (rank : 986)	NC score	0.068525 (rank : 622)
Query Neighborhood Hits	557	Target Neighborhood Hits	310	Shared Neighborhood Hits	78
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

YLPM1_MOUSE
θ value	θ > 10 (rank : 987)	NC score	0.066961 (rank : 631)
Query Neighborhood Hits	557	Target Neighborhood Hits	505	Shared Neighborhood Hits	95
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ZAN_HUMAN
θ value	θ > 10 (rank : 988)	NC score	0.255966 (rank : 279)
Query Neighborhood Hits	557	Target Neighborhood Hits	679	Shared Neighborhood Hits	269
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ZN207_HUMAN
θ value	θ > 10 (rank : 989)	NC score	0.066857 (rank : 633)
Query Neighborhood Hits	557	Target Neighborhood Hits	326	Shared Neighborhood Hits	65
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

ZN330_HUMAN
θ value	θ > 10 (rank : 990)	NC score	0.052194 (rank : 794)
Query Neighborhood Hits	557	Target Neighborhood Hits	83	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y3S2	Gene names	ZNF330, NOA36
Domain Architecture	No domain graphic available
Description	Zinc finger protein 330 (Nucleolar cysteine-rich protein) (Nucleolar autoantigen 36).

ZNFX1_HUMAN
θ value	θ > 10 (rank : 991)	NC score	0.099979 (rank : 482)
Query Neighborhood Hits	557	Target Neighborhood Hits	308	Shared Neighborhood Hits	88
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ZNFX1_MOUSE
θ value	θ > 10 (rank : 992)	NC score	0.100891 (rank : 477)
Query Neighborhood Hits	557	Target Neighborhood Hits	407	Shared Neighborhood Hits	97
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

Hits sorted by NC score

MEGF9_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	557	Target Neighborhood Hits	557	Shared Neighborhood Hits	557
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEGF9_MOUSE
NC score	0.923296 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	557	Target Neighborhood Hits	896	Shared Neighborhood Hits	364
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

LAMB2_HUMAN
NC score	0.867529 (rank : 3)	θ value	4.70527e-49 (rank : 5)
Query Neighborhood Hits	557	Target Neighborhood Hits	692	Shared Neighborhood Hits	282
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB2_MOUSE
NC score	0.867212 (rank : 4)	θ value	3.60269e-49 (rank : 4)
Query Neighborhood Hits	557	Target Neighborhood Hits	722	Shared Neighborhood Hits	287
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMC3_MOUSE
NC score	0.863816 (rank : 5)	θ value	1.37539e-32 (rank : 17)
Query Neighborhood Hits	557	Target Neighborhood Hits	624	Shared Neighborhood Hits	299
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC3_HUMAN
NC score	0.863346 (rank : 6)	θ value	1.6813e-30 (rank : 20)
Query Neighborhood Hits	557	Target Neighborhood Hits	588	Shared Neighborhood Hits	297
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMA5_MOUSE
NC score	0.860843 (rank : 7)	θ value	6.17384e-33 (rank : 15)
Query Neighborhood Hits	557	Target Neighborhood Hits	828	Shared Neighborhood Hits	322
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMA5_HUMAN
NC score	0.851616 (rank : 8)	θ value	2.50655e-34 (rank : 14)
Query Neighborhood Hits	557	Target Neighborhood Hits	976	Shared Neighborhood Hits	323
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB3_MOUSE
NC score	0.845123 (rank : 9)	θ value	4.28545e-26 (rank : 24)
Query Neighborhood Hits	557	Target Neighborhood Hits	444	Shared Neighborhood Hits	229
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LAMA1_HUMAN
NC score	0.835900 (rank : 10)	θ value	4.88048e-38 (rank : 11)
Query Neighborhood Hits	557	Target Neighborhood Hits	804	Shared Neighborhood Hits	305
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA1_MOUSE
NC score	0.832799 (rank : 11)	θ value	3.61106e-41 (rank : 8)
Query Neighborhood Hits	557	Target Neighborhood Hits	838	Shared Neighborhood Hits	314
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMB3_HUMAN
NC score	0.830362 (rank : 12)	θ value	2.77775e-25 (rank : 25)
Query Neighborhood Hits	557	Target Neighborhood Hits	461	Shared Neighborhood Hits	204
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMB1_MOUSE
NC score	0.821651 (rank : 13)	θ value	6.14528e-49 (rank : 6)
Query Neighborhood Hits	557	Target Neighborhood Hits	919	Shared Neighborhood Hits	273
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMC2_MOUSE
NC score	0.818895 (rank : 14)	θ value	1.92365e-26 (rank : 23)
Query Neighborhood Hits	557	Target Neighborhood Hits	614	Shared Neighborhood Hits	283
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LAMC1_MOUSE
NC score	0.807976 (rank : 15)	θ value	5.96599e-36 (rank : 13)
Query Neighborhood Hits	557	Target Neighborhood Hits	856	Shared Neighborhood Hits	288
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

SREC2_HUMAN
NC score	0.801257 (rank : 16)	θ value	9.56915e-18 (rank : 34)
Query Neighborhood Hits	557	Target Neighborhood Hits	645	Shared Neighborhood Hits	337
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SREC2_MOUSE
NC score	0.799871 (rank : 17)	θ value	1.63225e-17 (rank : 36)
Query Neighborhood Hits	557	Target Neighborhood Hits	605	Shared Neighborhood Hits	326
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

NTNG2_HUMAN
NC score	0.796103 (rank : 18)	θ value	3.18553e-13 (rank : 46)
Query Neighborhood Hits	557	Target Neighborhood Hits	276	Shared Neighborhood Hits	208
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

NTNG1_HUMAN
NC score	0.794052 (rank : 19)	θ value	3.07829e-16 (rank : 43)
Query Neighborhood Hits	557	Target Neighborhood Hits	247	Shared Neighborhood Hits	197
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG1_MOUSE
NC score	0.793145 (rank : 20)	θ value	1.38178e-16 (rank : 42)
Query Neighborhood Hits	557	Target Neighborhood Hits	246	Shared Neighborhood Hits	197
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

LAMB1_HUMAN
NC score	0.792852 (rank : 21)	θ value	3.60269e-49 (rank : 3)
Query Neighborhood Hits	557	Target Neighborhood Hits	1018	Shared Neighborhood Hits	283
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

NTNG2_MOUSE
NC score	0.790709 (rank : 22)	θ value	1.86753e-13 (rank : 45)
Query Neighborhood Hits	557	Target Neighborhood Hits	276	Shared Neighborhood Hits	217
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

LAMC2_HUMAN
NC score	0.789359 (rank : 23)	θ value	2.96777e-27 (rank : 22)
Query Neighborhood Hits	557	Target Neighborhood Hits	715	Shared Neighborhood Hits	277
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LAMA3_MOUSE
NC score	0.787977 (rank : 24)	θ value	2.68423e-28 (rank : 21)
Query Neighborhood Hits	557	Target Neighborhood Hits	859	Shared Neighborhood Hits	295
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LAMA2_HUMAN
NC score	0.786998 (rank : 25)	θ value	7.52953e-39 (rank : 10)
Query Neighborhood Hits	557	Target Neighborhood Hits	1092	Shared Neighborhood Hits	305
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

NET4_HUMAN
NC score	0.786997 (rank : 26)	θ value	4.58923e-20 (rank : 30)
Query Neighborhood Hits	557	Target Neighborhood Hits	191	Shared Neighborhood Hits	160
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

NET4_MOUSE
NC score	0.786765 (rank : 27)	θ value	9.24701e-21 (rank : 29)
Query Neighborhood Hits	557	Target Neighborhood Hits	180	Shared Neighborhood Hits	157
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

SREC_HUMAN
NC score	0.784296 (rank : 28)	θ value	3.63628e-17 (rank : 37)
Query Neighborhood Hits	557	Target Neighborhood Hits	645	Shared Neighborhood Hits	319
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

LAMC1_HUMAN
NC score	0.783854 (rank : 29)	θ value	6.17384e-33 (rank : 16)
Query Neighborhood Hits	557	Target Neighborhood Hits	922	Shared Neighborhood Hits	286
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

NET2_MOUSE
NC score	0.774288 (rank : 30)	θ value	6.20254e-17 (rank : 40)
Query Neighborhood Hits	557	Target Neighborhood Hits	193	Shared Neighborhood Hits	161
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

NET2_HUMAN
NC score	0.772764 (rank : 31)	θ value	1.058e-16 (rank : 41)
Query Neighborhood Hits	557	Target Neighborhood Hits	194	Shared Neighborhood Hits	156
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

LAMA2_MOUSE
NC score	0.759333 (rank : 32)	θ value	1.62093e-41 (rank : 7)
Query Neighborhood Hits	557	Target Neighborhood Hits	1198	Shared Neighborhood Hits	302
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

USH2A_MOUSE
NC score	0.754809 (rank : 33)	θ value	4.88048e-38 (rank : 12)
Query Neighborhood Hits	557	Target Neighborhood Hits	626	Shared Neighborhood Hits	283
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

NET1_HUMAN
NC score	0.750037 (rank : 34)	θ value	4.74913e-17 (rank : 39)
Query Neighborhood Hits	557	Target Neighborhood Hits	149	Shared Neighborhood Hits	127
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

NET1_MOUSE
NC score	0.747750 (rank : 35)	θ value	1.63225e-17 (rank : 35)
Query Neighborhood Hits	557	Target Neighborhood Hits	151	Shared Neighborhood Hits	127
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

MEGF8_HUMAN
NC score	0.744235 (rank : 36)	θ value	1.02238e-19 (rank : 31)
Query Neighborhood Hits	557	Target Neighborhood Hits	528	Shared Neighborhood Hits	283
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

USH2A_HUMAN
NC score	0.738328 (rank : 37)	θ value	6.81017e-40 (rank : 9)
Query Neighborhood Hits	557	Target Neighborhood Hits	600	Shared Neighborhood Hits	272
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

AGRIN_HUMAN
NC score	0.735318 (rank : 38)	θ value	4.74913e-17 (rank : 38)
Query Neighborhood Hits	557	Target Neighborhood Hits	582	Shared Neighborhood Hits	300
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

LAMA4_MOUSE
NC score	0.734721 (rank : 39)	θ value	1.52067e-31 (rank : 18)
Query Neighborhood Hits	557	Target Neighborhood Hits	584	Shared Neighborhood Hits	205
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

MEGF8_MOUSE
NC score	0.733072 (rank : 40)	θ value	1.74391e-19 (rank : 32)
Query Neighborhood Hits	557	Target Neighborhood Hits	520	Shared Neighborhood Hits	277
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

LAMA3_HUMAN
NC score	0.714236 (rank : 41)	θ value	1.09232e-21 (rank : 28)
Query Neighborhood Hits	557	Target Neighborhood Hits	760	Shared Neighborhood Hits	240
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

MEGF6_HUMAN
NC score	0.713180 (rank : 42)	θ value	1.13037e-18 (rank : 33)
Query Neighborhood Hits	557	Target Neighborhood Hits	671	Shared Neighborhood Hits	318
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

LAMA4_HUMAN
NC score	0.694624 (rank : 43)	θ value	1.28732e-30 (rank : 19)
Query Neighborhood Hits	557	Target Neighborhood Hits	708	Shared Neighborhood Hits	202
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

KRA51_HUMAN
NC score	0.683152 (rank : 44)	θ value	0.00102713 (rank : 162)
Query Neighborhood Hits	557	Target Neighborhood Hits	288	Shared Neighborhood Hits	183
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA53_HUMAN
NC score	0.659338 (rank : 45)	θ value	3.41135e-07 (rank : 97)
Query Neighborhood Hits	557	Target Neighborhood Hits	331	Shared Neighborhood Hits	207
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

DLK_HUMAN
NC score	0.657108 (rank : 46)	θ value	1.99992e-07 (rank : 95)
Query Neighborhood Hits	557	Target Neighborhood Hits	401	Shared Neighborhood Hits	267
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLL4_MOUSE
NC score	0.656618 (rank : 47)	θ value	1.53129e-07 (rank : 93)
Query Neighborhood Hits	557	Target Neighborhood Hits	440	Shared Neighborhood Hits	280
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL4_HUMAN
NC score	0.653683 (rank : 48)	θ value	6.21693e-09 (rank : 72)
Query Neighborhood Hits	557	Target Neighborhood Hits	435	Shared Neighborhood Hits	278
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL1_HUMAN
NC score	0.650223 (rank : 49)	θ value	7.34386e-10 (rank : 66)
Query Neighborhood Hits	557	Target Neighborhood Hits	455	Shared Neighborhood Hits	281
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

JAG1_MOUSE
NC score	0.649243 (rank : 50)	θ value	6.64225e-11 (rank : 58)
Query Neighborhood Hits	557	Target Neighborhood Hits	518	Shared Neighborhood Hits	283
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG1_HUMAN
NC score	0.648593 (rank : 51)	θ value	8.67504e-11 (rank : 59)
Query Neighborhood Hits	557	Target Neighborhood Hits	514	Shared Neighborhood Hits	286
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

DLL1_MOUSE
NC score	0.647440 (rank : 52)	θ value	8.11959e-09 (rank : 74)
Query Neighborhood Hits	557	Target Neighborhood Hits	456	Shared Neighborhood Hits	287
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

WIF1_MOUSE
NC score	0.646294 (rank : 53)	θ value	2.88788e-06 (rank : 113)
Query Neighborhood Hits	557	Target Neighborhood Hits	393	Shared Neighborhood Hits	264
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

STAB1_HUMAN
NC score	0.642591 (rank : 54)	θ value	1.63604e-09 (rank : 70)
Query Neighborhood Hits	557	Target Neighborhood Hits	546	Shared Neighborhood Hits	300
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

DLK_MOUSE
NC score	0.642534 (rank : 55)	θ value	0.000158464 (rank : 142)
Query Neighborhood Hits	557	Target Neighborhood Hits	374	Shared Neighborhood Hits	259
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

STAB2_HUMAN
NC score	0.640800 (rank : 56)	θ value	1.9326e-10 (rank : 64)
Query Neighborhood Hits	557	Target Neighborhood Hits	534	Shared Neighborhood Hits	297
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

STAB2_MOUSE
NC score	0.639790 (rank : 57)	θ value	1.74796e-11 (rank : 56)
Query Neighborhood Hits	557	Target Neighborhood Hits	528	Shared Neighborhood Hits	308
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

JAG2_HUMAN
NC score	0.638895 (rank : 58)	θ value	3.08544e-08 (rank : 82)
Query Neighborhood Hits	557	Target Neighborhood Hits	491	Shared Neighborhood Hits	277
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

DNER_HUMAN
NC score	0.638581 (rank : 59)	θ value	2.36244e-08 (rank : 81)
Query Neighborhood Hits	557	Target Neighborhood Hits	460	Shared Neighborhood Hits	269
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

STAB1_MOUSE
NC score	0.637824 (rank : 60)	θ value	2.52405e-10 (rank : 65)
Query Neighborhood Hits	557	Target Neighborhood Hits	566	Shared Neighborhood Hits	305
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

JAG2_MOUSE
NC score	0.637744 (rank : 61)	θ value	7.59969e-07 (rank : 102)
Query Neighborhood Hits	557	Target Neighborhood Hits	504	Shared Neighborhood Hits	280
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

DNER_MOUSE
NC score	0.636591 (rank : 62)	θ value	5.26297e-08 (rank : 85)
Query Neighborhood Hits	557	Target Neighborhood Hits	413	Shared Neighborhood Hits	260
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

WIF1_HUMAN
NC score	0.635536 (rank : 63)	θ value	8.40245e-06 (rank : 118)
Query Neighborhood Hits	557	Target Neighborhood Hits	392	Shared Neighborhood Hits	265
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

DLL3_HUMAN
NC score	0.634828 (rank : 64)	θ value	0.000121331 (rank : 136)
Query Neighborhood Hits	557	Target Neighborhood Hits	419	Shared Neighborhood Hits	259
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

KRA59_HUMAN
NC score	0.631650 (rank : 65)	θ value	3.19293e-05 (rank : 126)
Query Neighborhood Hits	557	Target Neighborhood Hits	310	Shared Neighborhood Hits	182
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

CRUM1_MOUSE
NC score	0.629271 (rank : 66)	θ value	4.0297e-08 (rank : 84)
Query Neighborhood Hits	557	Target Neighborhood Hits	444	Shared Neighborhood Hits	261
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

EGFL9_HUMAN
NC score	0.628968 (rank : 67)	θ value	2.21117e-06 (rank : 111)
Query Neighborhood Hits	557	Target Neighborhood Hits	365	Shared Neighborhood Hits	257
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

DLL3_MOUSE
NC score	0.628434 (rank : 68)	θ value	2.44474e-05 (rank : 122)
Query Neighborhood Hits	557	Target Neighborhood Hits	399	Shared Neighborhood Hits	255
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

CRUM1_HUMAN
NC score	0.625999 (rank : 69)	θ value	6.43352e-06 (rank : 116)
Query Neighborhood Hits	557	Target Neighborhood Hits	457	Shared Neighborhood Hits	261
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

KRA55_HUMAN
NC score	0.623810 (rank : 70)	θ value	9.29e-05 (rank : 131)
Query Neighborhood Hits	557	Target Neighborhood Hits	257	Shared Neighborhood Hits	166
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

CRUM2_HUMAN
NC score	0.623267 (rank : 71)	θ value	0.00020696 (rank : 146)
Query Neighborhood Hits	557	Target Neighborhood Hits	453	Shared Neighborhood Hits	267
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

EGFL9_MOUSE
NC score	0.620022 (rank : 72)	θ value	1.69304e-06 (rank : 109)
Query Neighborhood Hits	557	Target Neighborhood Hits	379	Shared Neighborhood Hits	259
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

CREL1_HUMAN
NC score	0.612406 (rank : 73)	θ value	1.33837e-11 (rank : 54)
Query Neighborhood Hits	557	Target Neighborhood Hits	441	Shared Neighborhood Hits	243
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

ATRN_HUMAN
NC score	0.608603 (rank : 74)	θ value	1.9326e-10 (rank : 61)
Query Neighborhood Hits	557	Target Neighborhood Hits	525	Shared Neighborhood Hits	240
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATRN_MOUSE
NC score	0.607993 (rank : 75)	θ value	3.64472e-09 (rank : 71)
Query Neighborhood Hits	557	Target Neighborhood Hits	519	Shared Neighborhood Hits	237
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

KRA58_HUMAN
NC score	0.607799 (rank : 76)	θ value	9.29e-05 (rank : 132)
Query Neighborhood Hits	557	Target Neighborhood Hits	324	Shared Neighborhood Hits	195
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

NOTC1_MOUSE
NC score	0.605234 (rank : 77)	θ value	1.133e-10 (rank : 60)
Query Neighborhood Hits	557	Target Neighborhood Hits	916	Shared Neighborhood Hits	308
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

KRA57_HUMAN
NC score	0.602857 (rank : 78)	θ value	0.00035302 (rank : 154)
Query Neighborhood Hits	557	Target Neighborhood Hits	269	Shared Neighborhood Hits	172
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA54_HUMAN
NC score	0.601232 (rank : 79)	θ value	0.00020696 (rank : 147)
Query Neighborhood Hits	557	Target Neighborhood Hits	270	Shared Neighborhood Hits	170
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

NAGPA_MOUSE
NC score	0.600817 (rank : 80)	θ value	4.1701e-05 (rank : 129)
Query Neighborhood Hits	557	Target Neighborhood Hits	308	Shared Neighborhood Hits	216
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NOTC1_HUMAN
NC score	0.589118 (rank : 81)	θ value	1.74796e-11 (rank : 55)
Query Neighborhood Hits	557	Target Neighborhood Hits	906	Shared Neighborhood Hits	304
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

CREL1_MOUSE
NC score	0.587928 (rank : 82)	θ value	7.84624e-12 (rank : 53)
Query Neighborhood Hits	557	Target Neighborhood Hits	524	Shared Neighborhood Hits	245
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

NOTC3_HUMAN
NC score	0.587342 (rank : 83)	θ value	8.97725e-08 (rank : 92)
Query Neighborhood Hits	557	Target Neighborhood Hits	1062	Shared Neighborhood Hits	323
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
NC score	0.586680 (rank : 84)	θ value	9.59137e-10 (rank : 67)
Query Neighborhood Hits	557	Target Neighborhood Hits	975	Shared Neighborhood Hits	316
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NAGPA_HUMAN
NC score	0.581791 (rank : 85)	θ value	0.00228821 (rank : 177)
Query Neighborhood Hits	557	Target Neighborhood Hits	282	Shared Neighborhood Hits	200
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NOTC2_MOUSE
NC score	0.575009 (rank : 86)	θ value	6.87365e-08 (rank : 89)
Query Neighborhood Hits	557	Target Neighborhood Hits	1069	Shared Neighborhood Hits	313
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC4_MOUSE
NC score	0.572819 (rank : 87)	θ value	5.08577e-11 (rank : 57)
Query Neighborhood Hits	557	Target Neighborhood Hits	872	Shared Neighborhood Hits	293
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC2_HUMAN
NC score	0.569790 (rank : 88)	θ value	1.06045e-08 (rank : 77)
Query Neighborhood Hits	557	Target Neighborhood Hits	1113	Shared Neighborhood Hits	330
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC4_HUMAN
NC score	0.569424 (rank : 89)	θ value	4.45536e-07 (rank : 99)
Query Neighborhood Hits	557	Target Neighborhood Hits	905	Shared Neighborhood Hits	299
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

KR510_HUMAN
NC score	0.563022 (rank : 90)	θ value	0.00665767 (rank : 193)
Query Neighborhood Hits	557	Target Neighborhood Hits	217	Shared Neighborhood Hits	135
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

PGBM_MOUSE
NC score	0.555934 (rank : 91)	θ value	7.56453e-23 (rank : 26)
Query Neighborhood Hits	557	Target Neighborhood Hits	1073	Shared Neighborhood Hits	310
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

KRA56_HUMAN
NC score	0.552771 (rank : 92)	θ value	0.0113563 (rank : 205)
Query Neighborhood Hits	557	Target Neighborhood Hits	207	Shared Neighborhood Hits	138
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

LTBP4_MOUSE
NC score	0.548509 (rank : 93)	θ value	0.000121331 (rank : 138)
Query Neighborhood Hits	557	Target Neighborhood Hits	607	Shared Neighborhood Hits	314
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

TENX_HUMAN
NC score	0.546653 (rank : 94)	θ value	3.77169e-06 (rank : 115)
Query Neighborhood Hits	557	Target Neighborhood Hits	789	Shared Neighborhood Hits	309
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

KRA52_HUMAN
NC score	0.545020 (rank : 95)	θ value	0.00509761 (rank : 188)
Query Neighborhood Hits	557	Target Neighborhood Hits	236	Shared Neighborhood Hits	153
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

TENA_HUMAN
NC score	0.543241 (rank : 96)	θ value	3.41135e-07 (rank : 98)
Query Neighborhood Hits	557	Target Neighborhood Hits	631	Shared Neighborhood Hits	284
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENA_MOUSE
NC score	0.543225 (rank : 97)	θ value	6.87365e-08 (rank : 90)
Query Neighborhood Hits	557	Target Neighborhood Hits	596	Shared Neighborhood Hits	282
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

KR511_HUMAN
NC score	0.542011 (rank : 98)	θ value	1.87187e-05 (rank : 121)
Query Neighborhood Hits	557	Target Neighborhood Hits	231	Shared Neighborhood Hits	140
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

PGBM_HUMAN
NC score	0.541667 (rank : 99)	θ value	9.87957e-23 (rank : 27)
Query Neighborhood Hits	557	Target Neighborhood Hits	1113	Shared Neighborhood Hits	316
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

NELL1_HUMAN
NC score	0.536576 (rank : 100)	θ value	0.00869519 (rank : 199)
Query Neighborhood Hits	557	Target Neighborhood Hits	451	Shared Neighborhood Hits	267
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

FBN3_HUMAN
NC score	0.533784 (rank : 101)	θ value	9.92553e-07 (rank : 105)
Query Neighborhood Hits	557	Target Neighborhood Hits	543	Shared Neighborhood Hits	286
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

LTBP2_MOUSE
NC score	0.532364 (rank : 102)	θ value	1.9326e-10 (rank : 63)
Query Neighborhood Hits	557	Target Neighborhood Hits	617	Shared Neighborhood Hits	301
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

FBN1_MOUSE
NC score	0.530271 (rank : 103)	θ value	1.09739e-05 (rank : 119)
Query Neighborhood Hits	557	Target Neighborhood Hits	563	Shared Neighborhood Hits	303
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_HUMAN
NC score	0.529068 (rank : 104)	θ value	6.87365e-08 (rank : 88)
Query Neighborhood Hits	557	Target Neighborhood Hits	557	Shared Neighborhood Hits	302
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

LTBP2_HUMAN
NC score	0.528640 (rank : 105)	θ value	3.08544e-08 (rank : 83)
Query Neighborhood Hits	557	Target Neighborhood Hits	552	Shared Neighborhood Hits	301
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

FBN2_HUMAN
NC score	0.528353 (rank : 106)	θ value	5.26297e-08 (rank : 86)
Query Neighborhood Hits	557	Target Neighborhood Hits	560	Shared Neighborhood Hits	295
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
NC score	0.526462 (rank : 107)	θ value	2.61198e-07 (rank : 96)
Query Neighborhood Hits	557	Target Neighborhood Hits	549	Shared Neighborhood Hits	292
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

NELL2_HUMAN
NC score	0.515007 (rank : 108)	θ value	2.44474e-05 (rank : 124)
Query Neighborhood Hits	557	Target Neighborhood Hits	449	Shared Neighborhood Hits	264
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
NC score	0.513400 (rank : 109)	θ value	0.00509761 (rank : 191)
Query Neighborhood Hits	557	Target Neighborhood Hits	436	Shared Neighborhood Hits	263
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

ITB6_MOUSE
NC score	0.510811 (rank : 110)	θ value	9.92553e-07 (rank : 107)
Query Neighborhood Hits	557	Target Neighborhood Hits	341	Shared Neighborhood Hits	235
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB5_MOUSE
NC score	0.510702 (rank : 111)	θ value	1.38499e-08 (rank : 80)
Query Neighborhood Hits	557	Target Neighborhood Hits	329	Shared Neighborhood Hits	232
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB6_HUMAN
NC score	0.503185 (rank : 112)	θ value	5.81887e-07 (rank : 101)
Query Neighborhood Hits	557	Target Neighborhood Hits	318	Shared Neighborhood Hits	230
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB5_HUMAN
NC score	0.500217 (rank : 113)	θ value	6.21693e-09 (rank : 73)
Query Neighborhood Hits	557	Target Neighborhood Hits	310	Shared Neighborhood Hits	225
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB2_MOUSE
NC score	0.498774 (rank : 114)	θ value	0.000270298 (rank : 151)
Query Neighborhood Hits	557	Target Neighborhood Hits	326	Shared Neighborhood Hits	236
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

LTBP3_MOUSE
NC score	0.498098 (rank : 115)	θ value	0.000121331 (rank : 137)
Query Neighborhood Hits	557	Target Neighborhood Hits	475	Shared Neighborhood Hits	286
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

ITB7_MOUSE
NC score	0.498074 (rank : 116)	θ value	0.000461057 (rank : 155)
Query Neighborhood Hits	557	Target Neighborhood Hits	277	Shared Neighborhood Hits	202
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

ITB7_HUMAN
NC score	0.498008 (rank : 117)	θ value	0.000786445 (rank : 159)
Query Neighborhood Hits	557	Target Neighborhood Hits	290	Shared Neighborhood Hits	212
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

LTBP3_HUMAN
NC score	0.497362 (rank : 118)	θ value	1.43324e-05 (rank : 120)
Query Neighborhood Hits	557	Target Neighborhood Hits	502	Shared Neighborhood Hits	273
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

PCSK5_MOUSE
NC score	0.495187 (rank : 119)	θ value	6.00763e-12 (rank : 52)
Query Neighborhood Hits	557	Target Neighborhood Hits	613	Shared Neighborhood Hits	298
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

HHIP_HUMAN
NC score	0.486280 (rank : 120)	θ value	0.00509761 (rank : 187)
Query Neighborhood Hits	557	Target Neighborhood Hits	249	Shared Neighborhood Hits	199
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

SCUB3_MOUSE
NC score	0.484327 (rank : 121)	θ value	6.43352e-06 (rank : 117)
Query Neighborhood Hits	557	Target Neighborhood Hits	442	Shared Neighborhood Hits	261
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_HUMAN
NC score	0.483985 (rank : 122)	θ value	2.44474e-05 (rank : 125)
Query Neighborhood Hits	557	Target Neighborhood Hits	428	Shared Neighborhood Hits	255
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

ITB3_HUMAN
NC score	0.481908 (rank : 123)	θ value	8.11959e-09 (rank : 75)
Query Neighborhood Hits	557	Target Neighborhood Hits	325	Shared Neighborhood Hits	226
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

LTB1L_HUMAN
NC score	0.480406 (rank : 124)	θ value	0.0252991 (rank : 233)
Query Neighborhood Hits	557	Target Neighborhood Hits	553	Shared Neighborhood Hits	283
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
NC score	0.479146 (rank : 125)	θ value	0.0252991 (rank : 234)
Query Neighborhood Hits	557	Target Neighborhood Hits	502	Shared Neighborhood Hits	267
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

CUBN_HUMAN
NC score	0.473431 (rank : 126)	θ value	0.00134147 (rank : 166)
Query Neighborhood Hits	557	Target Neighborhood Hits	482	Shared Neighborhood Hits	252
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

ITB2_HUMAN
NC score	0.472131 (rank : 127)	θ value	0.00175202 (rank : 171)
Query Neighborhood Hits	557	Target Neighborhood Hits	282	Shared Neighborhood Hits	214
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ZAN_MOUSE
NC score	0.472080 (rank : 128)	θ value	0.0193708 (rank : 226)
Query Neighborhood Hits	557	Target Neighborhood Hits	808	Shared Neighborhood Hits	342
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

LTB1L_MOUSE
NC score	0.470510 (rank : 129)	θ value	0.00134147 (rank : 168)
Query Neighborhood Hits	557	Target Neighborhood Hits	514	Shared Neighborhood Hits	272
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

FRAS1_HUMAN
NC score	0.470225 (rank : 130)	θ value	1.63604e-09 (rank : 68)
Query Neighborhood Hits	557	Target Neighborhood Hits	759	Shared Neighborhood Hits	290
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

LTB1S_MOUSE
NC score	0.469997 (rank : 131)	θ value	0.00134147 (rank : 169)
Query Neighborhood Hits	557	Target Neighborhood Hits	479	Shared Neighborhood Hits	260
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

ITB3_MOUSE
NC score	0.469135 (rank : 132)	θ value	9.92553e-07 (rank : 106)
Query Neighborhood Hits	557	Target Neighborhood Hits	319	Shared Neighborhood Hits	218
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

HHIP_MOUSE
NC score	0.466424 (rank : 133)	θ value	0.0148317 (rank : 209)
Query Neighborhood Hits	557	Target Neighborhood Hits	219	Shared Neighborhood Hits	178
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

ITB1_MOUSE
NC score	0.465411 (rank : 134)	θ value	0.00390308 (rank : 184)
Query Neighborhood Hits	557	Target Neighborhood Hits	283	Shared Neighborhood Hits	198
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

KR104_HUMAN
NC score	0.465236 (rank : 135)	θ value	0.0961366 (rank : 277)
Query Neighborhood Hits	557	Target Neighborhood Hits	313	Shared Neighborhood Hits	185
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

SLIT1_MOUSE
NC score	0.464676 (rank : 136)	θ value	1.53129e-07 (rank : 94)
Query Neighborhood Hits	557	Target Neighborhood Hits	715	Shared Neighborhood Hits	267
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

ITB1_HUMAN
NC score	0.464291 (rank : 137)	θ value	0.00869519 (rank : 198)
Query Neighborhood Hits	557	Target Neighborhood Hits	298	Shared Neighborhood Hits	203
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

KR171_HUMAN
NC score	0.463597 (rank : 138)	θ value	θ > 10 (rank : 741)
Query Neighborhood Hits	557	Target Neighborhood Hits	144	Shared Neighborhood Hits	108
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

SLIT1_HUMAN
NC score	0.461674 (rank : 139)	θ value	2.21117e-06 (rank : 112)
Query Neighborhood Hits	557	Target Neighborhood Hits	700	Shared Neighborhood Hits	260
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

CUBN_MOUSE
NC score	0.458551 (rank : 140)	θ value	0.21417 (rank : 300)
Query Neighborhood Hits	557	Target Neighborhood Hits	477	Shared Neighborhood Hits	249
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

COMP_MOUSE
NC score	0.457770 (rank : 141)	θ value	0.00869519 (rank : 196)
Query Neighborhood Hits	557	Target Neighborhood Hits	290	Shared Neighborhood Hits	210
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CRIM1_HUMAN
NC score	0.456942 (rank : 142)	θ value	0.00298849 (rank : 180)
Query Neighborhood Hits	557	Target Neighborhood Hits	362	Shared Neighborhood Hits	194
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

KR107_HUMAN
NC score	0.455885 (rank : 143)	θ value	0.0736092 (rank : 265)
Query Neighborhood Hits	557	Target Neighborhood Hits	330	Shared Neighborhood Hits	196
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

FRAS1_MOUSE
NC score	0.455308 (rank : 144)	θ value	1.9326e-10 (rank : 62)
Query Neighborhood Hits	557	Target Neighborhood Hits	747	Shared Neighborhood Hits	280
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

PROS_HUMAN
NC score	0.453423 (rank : 145)	θ value	0.00102713 (rank : 164)
Query Neighborhood Hits	557	Target Neighborhood Hits	340	Shared Neighborhood Hits	224
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

LRP1_HUMAN
NC score	0.453008 (rank : 146)	θ value	3.77169e-06 (rank : 114)
Query Neighborhood Hits	557	Target Neighborhood Hits	617	Shared Neighborhood Hits	291
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

SLIT2_HUMAN
NC score	0.451308 (rank : 147)	θ value	8.11959e-09 (rank : 76)
Query Neighborhood Hits	557	Target Neighborhood Hits	708	Shared Neighborhood Hits	262
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

ITB4_HUMAN
NC score	0.450448 (rank : 148)	θ value	0.00175202 (rank : 172)
Query Neighborhood Hits	557	Target Neighborhood Hits	458	Shared Neighborhood Hits	238
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

FBLN2_HUMAN
NC score	0.448840 (rank : 149)	θ value	0.0736092 (rank : 264)
Query Neighborhood Hits	557	Target Neighborhood Hits	392	Shared Neighborhood Hits	229
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

KR106_HUMAN
NC score	0.447358 (rank : 150)	θ value	0.0148317 (rank : 210)
Query Neighborhood Hits	557	Target Neighborhood Hits	347	Shared Neighborhood Hits	203
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

SLIT2_MOUSE
NC score	0.445674 (rank : 151)	θ value	1.63604e-09 (rank : 69)
Query Neighborhood Hits	557	Target Neighborhood Hits	684	Shared Neighborhood Hits	257
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

PROS_MOUSE
NC score	0.445631 (rank : 152)	θ value	0.000786445 (rank : 160)
Query Neighborhood Hits	557	Target Neighborhood Hits	330	Shared Neighborhood Hits	215
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

GAS6_HUMAN
NC score	0.443751 (rank : 153)	θ value	0.21417 (rank : 304)
Query Neighborhood Hits	557	Target Neighborhood Hits	348	Shared Neighborhood Hits	216
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

EGFL7_HUMAN
NC score	0.443653 (rank : 154)	θ value	0.125558 (rank : 284)
Query Neighborhood Hits	557	Target Neighborhood Hits	325	Shared Neighborhood Hits	210
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

FBLN2_MOUSE
NC score	0.442359 (rank : 155)	θ value	0.00390308 (rank : 183)
Query Neighborhood Hits	557	Target Neighborhood Hits	505	Shared Neighborhood Hits	254
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

SLIT3_MOUSE
NC score	0.440512 (rank : 156)	θ value	1.29631e-06 (rank : 108)
Query Neighborhood Hits	557	Target Neighborhood Hits	700	Shared Neighborhood Hits	268
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

TSP4_MOUSE
NC score	0.439316 (rank : 157)	θ value	0.0193708 (rank : 225)
Query Neighborhood Hits	557	Target Neighborhood Hits	276	Shared Neighborhood Hits	207
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

LRP1B_HUMAN
NC score	0.438922 (rank : 158)	θ value	3.19293e-05 (rank : 127)
Query Neighborhood Hits	557	Target Neighborhood Hits	602	Shared Neighborhood Hits	286
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1B_MOUSE
NC score	0.435792 (rank : 159)	θ value	3.19293e-05 (rank : 128)
Query Neighborhood Hits	557	Target Neighborhood Hits	606	Shared Neighborhood Hits	284
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

SLIT3_HUMAN
NC score	0.435786 (rank : 160)	θ value	1.06045e-08 (rank : 79)
Query Neighborhood Hits	557	Target Neighborhood Hits	682	Shared Neighborhood Hits	257
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

TSP4_HUMAN
NC score	0.435232 (rank : 161)	θ value	0.0736092 (rank : 271)
Query Neighborhood Hits	557	Target Neighborhood Hits	277	Shared Neighborhood Hits	198
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

C1QR1_HUMAN
NC score	0.435084 (rank : 162)	θ value	0.0563607 (rank : 250)
Query Neighborhood Hits	557	Target Neighborhood Hits	493	Shared Neighborhood Hits	252
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

COMP_HUMAN
NC score	0.434417 (rank : 163)	θ value	0.000786445 (rank : 158)
Query Neighborhood Hits	557	Target Neighborhood Hits	258	Shared Neighborhood Hits	190
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

GAS6_MOUSE
NC score	0.434405 (rank : 164)	θ value	8.99809 (rank : 547)
Query Neighborhood Hits	557	Target Neighborhood Hits	343	Shared Neighborhood Hits	220
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

FBLN1_MOUSE
NC score	0.432343 (rank : 165)	θ value	0.000158464 (rank : 143)
Query Neighborhood Hits	557	Target Neighborhood Hits	329	Shared Neighborhood Hits	214
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

NID2_HUMAN
NC score	0.428309 (rank : 166)	θ value	0.0148317 (rank : 211)
Query Neighborhood Hits	557	Target Neighborhood Hits	456	Shared Neighborhood Hits	224
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

C1QR1_MOUSE
NC score	0.427743 (rank : 167)	θ value	0.0252991 (rank : 228)
Query Neighborhood Hits	557	Target Neighborhood Hits	342	Shared Neighborhood Hits	213
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

TRBM_HUMAN
NC score	0.424139 (rank : 168)	θ value	0.0148317 (rank : 214)
Query Neighborhood Hits	557	Target Neighborhood Hits	339	Shared Neighborhood Hits	203
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

EDIL3_MOUSE
NC score	0.419917 (rank : 169)	θ value	6.88961 (rank : 514)
Query Neighborhood Hits	557	Target Neighborhood Hits	317	Shared Neighborhood Hits	204
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EGFL7_MOUSE
NC score	0.418646 (rank : 170)	θ value	4.03905 (rank : 468)
Query Neighborhood Hits	557	Target Neighborhood Hits	287	Shared Neighborhood Hits	195
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

FBLN1_HUMAN
NC score	0.416889 (rank : 171)	θ value	0.00134147 (rank : 167)
Query Neighborhood Hits	557	Target Neighborhood Hits	324	Shared Neighborhood Hits	218
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

TSP3_MOUSE
NC score	0.416649 (rank : 172)	θ value	0.00869519 (rank : 202)
Query Neighborhood Hits	557	Target Neighborhood Hits	247	Shared Neighborhood Hits	178
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

NID1_HUMAN
NC score	0.414236 (rank : 173)	θ value	0.279714 (rank : 316)
Query Neighborhood Hits	557	Target Neighborhood Hits	329	Shared Neighborhood Hits	211
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

TRBM_MOUSE
NC score	0.412768 (rank : 174)	θ value	θ > 10 (rank : 959)
Query Neighborhood Hits	557	Target Neighborhood Hits	361	Shared Neighborhood Hits	219
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

KR101_HUMAN
NC score	0.408731 (rank : 175)	θ value	0.125558 (rank : 290)
Query Neighborhood Hits	557	Target Neighborhood Hits	261	Shared Neighborhood Hits	157
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

NID1_MOUSE
NC score	0.406617 (rank : 176)	θ value	θ > 10 (rank : 832)
Query Neighborhood Hits	557	Target Neighborhood Hits	335	Shared Neighborhood Hits	209
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

TSP3_HUMAN
NC score	0.405672 (rank : 177)	θ value	0.00298849 (rank : 182)
Query Neighborhood Hits	557	Target Neighborhood Hits	250	Shared Neighborhood Hits	172
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

UROM_HUMAN
NC score	0.404562 (rank : 178)	θ value	θ > 10 (rank : 964)
Query Neighborhood Hits	557	Target Neighborhood Hits	284	Shared Neighborhood Hits	200
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

NID2_MOUSE
NC score	0.401930 (rank : 179)	θ value	0.0563607 (rank : 253)
Query Neighborhood Hits	557	Target Neighborhood Hits	338	Shared Neighborhood Hits	204
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

ITB8_HUMAN
NC score	0.396207 (rank : 180)	θ value	0.365318 (rank : 324)
Query Neighborhood Hits	557	Target Neighborhood Hits	280	Shared Neighborhood Hits	187
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

MATN2_HUMAN
NC score	0.395824 (rank : 181)	θ value	1.69304e-06 (rank : 110)
Query Neighborhood Hits	557	Target Neighborhood Hits	365	Shared Neighborhood Hits	202
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

TENR_MOUSE
NC score	0.392855 (rank : 182)	θ value	0.000270298 (rank : 152)
Query Neighborhood Hits	557	Target Neighborhood Hits	531	Shared Neighborhood Hits	260
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

UROM_MOUSE
NC score	0.392571 (rank : 183)	θ value	θ > 10 (rank : 965)
Query Neighborhood Hits	557	Target Neighborhood Hits	276	Shared Neighborhood Hits	200
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

FBLN5_HUMAN
NC score	0.392039 (rank : 184)	θ value	0.47712 (rank : 343)
Query Neighborhood Hits	557	Target Neighborhood Hits	329	Shared Neighborhood Hits	218
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

EGF_MOUSE
NC score	0.391993 (rank : 185)	θ value	3.0926 (rank : 442)
Query Neighborhood Hits	557	Target Neighborhood Hits	358	Shared Neighborhood Hits	223
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

TENR_HUMAN
NC score	0.386940 (rank : 186)	θ value	0.00020696 (rank : 150)
Query Neighborhood Hits	557	Target Neighborhood Hits	526	Shared Neighborhood Hits	257
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

FBLN5_MOUSE
NC score	0.386710 (rank : 187)	θ value	θ > 10 (rank : 690)
Query Neighborhood Hits	557	Target Neighborhood Hits	317	Shared Neighborhood Hits	208
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBLN4_HUMAN
NC score	0.386693 (rank : 188)	θ value	θ > 10 (rank : 688)
Query Neighborhood Hits	557	Target Neighborhood Hits	278	Shared Neighborhood Hits	188
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

EDIL3_HUMAN
NC score	0.385747 (rank : 189)	θ value	θ > 10 (rank : 666)
Query Neighborhood Hits	557	Target Neighborhood Hits	292	Shared Neighborhood Hits	186
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

MATN2_MOUSE
NC score	0.382806 (rank : 190)	θ value	9.29e-05 (rank : 133)
Query Neighborhood Hits	557	Target Neighborhood Hits	356	Shared Neighborhood Hits	198
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

CELR2_HUMAN
NC score	0.381571 (rank : 191)	θ value	2.0648e-12 (rank : 49)
Query Neighborhood Hits	557	Target Neighborhood Hits	657	Shared Neighborhood Hits	259
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CELR3_HUMAN
NC score	0.381380 (rank : 192)	θ value	2.69671e-12 (rank : 50)
Query Neighborhood Hits	557	Target Neighborhood Hits	680	Shared Neighborhood Hits	262
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CELR3_MOUSE
NC score	0.379489 (rank : 193)	θ value	5.43371e-13 (rank : 48)
Query Neighborhood Hits	557	Target Neighborhood Hits	687	Shared Neighborhood Hits	265
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

FBLN4_MOUSE
NC score	0.378217 (rank : 194)	θ value	θ > 10 (rank : 689)
Query Neighborhood Hits	557	Target Neighborhood Hits	270	Shared Neighborhood Hits	182
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN3_HUMAN
NC score	0.373034 (rank : 195)	θ value	0.00298849 (rank : 181)
Query Neighborhood Hits	557	Target Neighborhood Hits	293	Shared Neighborhood Hits	195
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

EGFL8_HUMAN
NC score	0.371795 (rank : 196)	θ value	θ > 10 (rank : 667)
Query Neighborhood Hits	557	Target Neighborhood Hits	270	Shared Neighborhood Hits	173
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

KR102_HUMAN
NC score	0.370146 (rank : 197)	θ value	0.125558 (rank : 291)
Query Neighborhood Hits	557	Target Neighborhood Hits	264	Shared Neighborhood Hits	152
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

CELR1_HUMAN
NC score	0.368231 (rank : 198)	θ value	4.16044e-13 (rank : 47)
Query Neighborhood Hits	557	Target Neighborhood Hits	613	Shared Neighborhood Hits	242
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

LRP2_HUMAN
NC score	0.368169 (rank : 199)	θ value	0.00102713 (rank : 163)
Query Neighborhood Hits	557	Target Neighborhood Hits	573	Shared Neighborhood Hits	284
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

CELR1_MOUSE
NC score	0.367183 (rank : 200)	θ value	1.09485e-13 (rank : 44)
Query Neighborhood Hits	557	Target Neighborhood Hits	617	Shared Neighborhood Hits	246
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

EGFL8_MOUSE
NC score	0.364789 (rank : 201)	θ value	θ > 10 (rank : 668)
Query Neighborhood Hits	557	Target Neighborhood Hits	266	Shared Neighborhood Hits	174
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

CELR2_MOUSE
NC score	0.362349 (rank : 202)	θ value	3.52202e-12 (rank : 51)
Query Neighborhood Hits	557	Target Neighborhood Hits	584	Shared Neighborhood Hits	242
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

EMR1_HUMAN
NC score	0.359399 (rank : 203)	θ value	1.38821 (rank : 384)
Query Neighborhood Hits	557	Target Neighborhood Hits	382	Shared Neighborhood Hits	204
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

SUSD1_HUMAN
NC score	0.359398 (rank : 204)	θ value	0.47712 (rank : 348)
Query Neighborhood Hits	557	Target Neighborhood Hits	285	Shared Neighborhood Hits	170
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

CSPG3_MOUSE
NC score	0.357332 (rank : 205)	θ value	0.000158464 (rank : 141)
Query Neighborhood Hits	557	Target Neighborhood Hits	657	Shared Neighborhood Hits	251
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

KR105_HUMAN
NC score	0.356213 (rank : 206)	θ value	θ > 10 (rank : 733)
Query Neighborhood Hits	557	Target Neighborhood Hits	271	Shared Neighborhood Hits	164
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

FBLN3_MOUSE
NC score	0.355379 (rank : 207)	θ value	0.813845 (rank : 360)
Query Neighborhood Hits	557	Target Neighborhood Hits	279	Shared Neighborhood Hits	183
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

EGF_HUMAN
NC score	0.355151 (rank : 208)	θ value	θ > 10 (rank : 670)
Query Neighborhood Hits	557	Target Neighborhood Hits	343	Shared Neighborhood Hits	209
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

KR109_HUMAN
NC score	0.350229 (rank : 209)	θ value	0.0330416 (rank : 240)
Query Neighborhood Hits	557	Target Neighborhood Hits	226	Shared Neighborhood Hits	136
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

CSPG3_HUMAN
NC score	0.346192 (rank : 210)	θ value	0.0736092 (rank : 261)
Query Neighborhood Hits	557	Target Neighborhood Hits	676	Shared Neighborhood Hits	240
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

KR108_HUMAN
NC score	0.344207 (rank : 211)	θ value	0.365318 (rank : 326)
Query Neighborhood Hits	557	Target Neighborhood Hits	226	Shared Neighborhood Hits	136
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

EMR2_HUMAN
NC score	0.343236 (rank : 212)	θ value	θ > 10 (rank : 672)
Query Neighborhood Hits	557	Target Neighborhood Hits	345	Shared Neighborhood Hits	192
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

KR10B_HUMAN
NC score	0.342692 (rank : 213)	θ value	0.0252991 (rank : 232)
Query Neighborhood Hits	557	Target Neighborhood Hits	269	Shared Neighborhood Hits	149
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KR10C_HUMAN
NC score	0.342156 (rank : 214)	θ value	0.0961366 (rank : 278)
Query Neighborhood Hits	557	Target Neighborhood Hits	219	Shared Neighborhood Hits	134
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

CD97_HUMAN
NC score	0.340557 (rank : 215)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	557	Target Neighborhood Hits	353	Shared Neighborhood Hits	193
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CSPG2_MOUSE
NC score	0.339388 (rank : 216)	θ value	0.0193708 (rank : 216)
Query Neighborhood Hits	557	Target Neighborhood Hits	711	Shared Neighborhood Hits	242
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CD248_HUMAN
NC score	0.337042 (rank : 217)	θ value	0.0961366 (rank : 275)
Query Neighborhood Hits	557	Target Neighborhood Hits	679	Shared Neighborhood Hits	239
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CSPG2_HUMAN
NC score	0.336090 (rank : 218)	θ value	0.000602161 (rank : 156)
Query Neighborhood Hits	557	Target Neighborhood Hits	681	Shared Neighborhood Hits	235
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CD248_MOUSE
NC score	0.327435 (rank : 219)	θ value	1.38821 (rank : 381)
Query Neighborhood Hits	557	Target Neighborhood Hits	578	Shared Neighborhood Hits	207
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

GRN_HUMAN
NC score	0.326592 (rank : 220)	θ value	θ > 10 (rank : 720)
Query Neighborhood Hits	557	Target Neighborhood Hits	268	Shared Neighborhood Hits	162
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

FATH_HUMAN
NC score	0.324500 (rank : 221)	θ value	2.44474e-05 (rank : 123)
Query Neighborhood Hits	557	Target Neighborhood Hits	570	Shared Neighborhood Hits	239
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

GRN_MOUSE
NC score	0.324225 (rank : 222)	θ value	2.36792 (rank : 425)
Query Neighborhood Hits	557	Target Neighborhood Hits	248	Shared Neighborhood Hits	158
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

EMR1_MOUSE
NC score	0.323765 (rank : 223)	θ value	θ > 10 (rank : 671)
Query Neighborhood Hits	557	Target Neighborhood Hits	349	Shared Neighborhood Hits	180
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

VLDLR_HUMAN
NC score	0.322824 (rank : 224)	θ value	θ > 10 (rank : 968)
Query Neighborhood Hits	557	Target Neighborhood Hits	383	Shared Neighborhood Hits	218
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

TENN_MOUSE
NC score	0.322539 (rank : 225)	θ value	5.27518 (rank : 500)
Query Neighborhood Hits	557	Target Neighborhood Hits	484	Shared Neighborhood Hits	240
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENN_HUMAN
NC score	0.322437 (rank : 226)	θ value	θ > 10 (rank : 924)
Query Neighborhood Hits	557	Target Neighborhood Hits	453	Shared Neighborhood Hits	240
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

PCSK5_HUMAN
NC score	0.322226 (rank : 227)	θ value	1.06045e-08 (rank : 78)
Query Neighborhood Hits	557	Target Neighborhood Hits	291	Shared Neighborhood Hits	184
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

VLDLR_MOUSE
NC score	0.319700 (rank : 228)	θ value	θ > 10 (rank : 969)
Query Neighborhood Hits	557	Target Neighborhood Hits	360	Shared Neighborhood Hits	204
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

KRA11_HUMAN
NC score	0.315612 (rank : 229)	θ value	0.21417 (rank : 305)
Query Neighborhood Hits	557	Target Neighborhood Hits	155	Shared Neighborhood Hits	101
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

SSPO_MOUSE
NC score	0.314510 (rank : 230)	θ value	0.0252991 (rank : 237)
Query Neighborhood Hits	557	Target Neighborhood Hits	800	Shared Neighborhood Hits	314
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

MUC5B_HUMAN
NC score	0.311304 (rank : 231)	θ value	0.365318 (rank : 328)
Query Neighborhood Hits	557	Target Neighborhood Hits	1020	Shared Neighborhood Hits	328
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

LDLR_HUMAN
NC score	0.310874 (rank : 232)	θ value	θ > 10 (rank : 775)
Query Neighborhood Hits	557	Target Neighborhood Hits	375	Shared Neighborhood Hits	223
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP8_MOUSE
NC score	0.310453 (rank : 233)	θ value	0.0961366 (rank : 279)
Query Neighborhood Hits	557	Target Neighborhood Hits	385	Shared Neighborhood Hits	209
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

TSP1_MOUSE
NC score	0.310210 (rank : 234)	θ value	0.00869519 (rank : 201)
Query Neighborhood Hits	557	Target Neighborhood Hits	396	Shared Neighborhood Hits	213
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

PROZ_MOUSE
NC score	0.307985 (rank : 235)	θ value	0.163984 (rank : 297)
Query Neighborhood Hits	557	Target Neighborhood Hits	410	Shared Neighborhood Hits	183
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

TSP1_HUMAN
NC score	0.305638 (rank : 236)	θ value	0.0113563 (rank : 206)
Query Neighborhood Hits	557	Target Neighborhood Hits	389	Shared Neighborhood Hits	211
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

KRA47_HUMAN
NC score	0.303965 (rank : 237)	θ value	θ > 10 (rank : 752)
Query Neighborhood Hits	557	Target Neighborhood Hits	204	Shared Neighborhood Hits	117
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

PROZ_HUMAN
NC score	0.301676 (rank : 238)	θ value	1.06291 (rank : 378)
Query Neighborhood Hits	557	Target Neighborhood Hits	422	Shared Neighborhood Hits	189
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

MATN3_HUMAN
NC score	0.300516 (rank : 239)	θ value	0.0431538 (rank : 246)
Query Neighborhood Hits	557	Target Neighborhood Hits	268	Shared Neighborhood Hits	157
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_MOUSE
NC score	0.299346 (rank : 240)	θ value	0.0193708 (rank : 221)
Query Neighborhood Hits	557	Target Neighborhood Hits	261	Shared Neighborhood Hits	157
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
NC score	0.297959 (rank : 241)	θ value	θ > 10 (rank : 799)
Query Neighborhood Hits	557	Target Neighborhood Hits	287	Shared Neighborhood Hits	169
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

LDLR_MOUSE
NC score	0.296215 (rank : 242)	θ value	θ > 10 (rank : 776)
Query Neighborhood Hits	557	Target Neighborhood Hits	382	Shared Neighborhood Hits	216
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

ESM1_HUMAN
NC score	0.294085 (rank : 243)	θ value	0.47712 (rank : 342)
Query Neighborhood Hits	557	Target Neighborhood Hits	110	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

MFGM_MOUSE
NC score	0.293379 (rank : 244)	θ value	1.06291 (rank : 374)
Query Neighborhood Hits	557	Target Neighborhood Hits	233	Shared Neighborhood Hits	154
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

KRA13_HUMAN
NC score	0.291065 (rank : 245)	θ value	θ > 10 (rank : 748)
Query Neighborhood Hits	557	Target Neighborhood Hits	144	Shared Neighborhood Hits	94
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

NRX1A_HUMAN
NC score	0.289327 (rank : 246)	θ value	θ > 10 (rank : 840)
Query Neighborhood Hits	557	Target Neighborhood Hits	170	Shared Neighborhood Hits	108
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
NC score	0.287473 (rank : 247)	θ value	θ > 10 (rank : 841)
Query Neighborhood Hits	557	Target Neighborhood Hits	164	Shared Neighborhood Hits	107
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

LYAM2_MOUSE
NC score	0.287237 (rank : 248)	θ value	0.00020696 (rank : 148)
Query Neighborhood Hits	557	Target Neighborhood Hits	420	Shared Neighborhood Hits	203
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

MT3_MOUSE
NC score	0.286756 (rank : 249)	θ value	θ > 10 (rank : 823)
Query Neighborhood Hits	557	Target Neighborhood Hits	68	Shared Neighborhood Hits	46
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

KRA94_HUMAN
NC score	0.285467 (rank : 250)	θ value	θ > 10 (rank : 756)
Query Neighborhood Hits	557	Target Neighborhood Hits	204	Shared Neighborhood Hits	134
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

PCSK6_HUMAN
NC score	0.284976 (rank : 251)	θ value	9.29e-05 (rank : 134)
Query Neighborhood Hits	557	Target Neighborhood Hits	298	Shared Neighborhood Hits	168
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

ELTD1_MOUSE
NC score	0.283969 (rank : 252)	θ value	5.27518 (rank : 489)
Query Neighborhood Hits	557	Target Neighborhood Hits	288	Shared Neighborhood Hits	159
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

MATN4_MOUSE
NC score	0.283468 (rank : 253)	θ value	6.88961 (rank : 525)
Query Neighborhood Hits	557	Target Neighborhood Hits	277	Shared Neighborhood Hits	161
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

KR10A_HUMAN
NC score	0.283035 (rank : 254)	θ value	1.81305 (rank : 405)
Query Neighborhood Hits	557	Target Neighborhood Hits	232	Shared Neighborhood Hits	138
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

NFX1_HUMAN
NC score	0.282350 (rank : 255)	θ value	0.365318 (rank : 329)
Query Neighborhood Hits	557	Target Neighborhood Hits	405	Shared Neighborhood Hits	150
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

LRP8_HUMAN
NC score	0.281947 (rank : 256)	θ value	θ > 10 (rank : 793)
Query Neighborhood Hits	557	Target Neighborhood Hits	346	Shared Neighborhood Hits	195
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

TNR16_HUMAN
NC score	0.281823 (rank : 257)	θ value	0.0563607 (rank : 258)
Query Neighborhood Hits	557	Target Neighborhood Hits	183	Shared Neighborhood Hits	117
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

KRA93_HUMAN
NC score	0.280839 (rank : 258)	θ value	θ > 10 (rank : 755)
Query Neighborhood Hits	557	Target Neighborhood Hits	203	Shared Neighborhood Hits	121
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA45_HUMAN
NC score	0.277194 (rank : 259)	θ value	θ > 10 (rank : 751)
Query Neighborhood Hits	557	Target Neighborhood Hits	194	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

NRX3A_HUMAN
NC score	0.277182 (rank : 260)	θ value	θ > 10 (rank : 843)
Query Neighborhood Hits	557	Target Neighborhood Hits	164	Shared Neighborhood Hits	104
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

LRP4_MOUSE
NC score	0.274332 (rank : 261)	θ value	θ > 10 (rank : 788)
Query Neighborhood Hits	557	Target Neighborhood Hits	351	Shared Neighborhood Hits	192
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

NRX2A_HUMAN
NC score	0.274111 (rank : 262)	θ value	0.0736092 (rank : 268)
Query Neighborhood Hits	557	Target Neighborhood Hits	614	Shared Neighborhood Hits	142
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

KR414_HUMAN
NC score	0.273644 (rank : 263)	θ value	θ > 10 (rank : 747)
Query Neighborhood Hits	557	Target Neighborhood Hits	199	Shared Neighborhood Hits	116
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

LRP4_HUMAN
NC score	0.272832 (rank : 264)	θ value	θ > 10 (rank : 787)
Query Neighborhood Hits	557	Target Neighborhood Hits	355	Shared Neighborhood Hits	198
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

TNR4_MOUSE
NC score	0.271490 (rank : 265)	θ value	0.365318 (rank : 336)
Query Neighborhood Hits	557	Target Neighborhood Hits	137	Shared Neighborhood Hits	87
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

KRA98_HUMAN
NC score	0.269974 (rank : 266)	θ value	θ > 10 (rank : 757)
Query Neighborhood Hits	557	Target Neighborhood Hits	185	Shared Neighborhood Hits	110
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KR103_HUMAN
NC score	0.269894 (rank : 267)	θ value	5.27518 (rank : 496)
Query Neighborhood Hits	557	Target Neighborhood Hits	212	Shared Neighborhood Hits	121
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

TSP2_MOUSE
NC score	0.268339 (rank : 268)	θ value	1.81305 (rank : 416)
Query Neighborhood Hits	557	Target Neighborhood Hits	352	Shared Neighborhood Hits	191
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

CD97_MOUSE
NC score	0.268011 (rank : 269)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	557	Target Neighborhood Hits	295	Shared Neighborhood Hits	157
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

SORL_MOUSE
NC score	0.267165 (rank : 270)	θ value	0.0563607 (rank : 257)
Query Neighborhood Hits	557	Target Neighborhood Hits	439	Shared Neighborhood Hits	206
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

CFC1_HUMAN
NC score	0.266828 (rank : 271)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	557	Target Neighborhood Hits	148	Shared Neighborhood Hits	119
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

KRA92_HUMAN
NC score	0.266709 (rank : 272)	θ value	θ > 10 (rank : 754)
Query Neighborhood Hits	557	Target Neighborhood Hits	198	Shared Neighborhood Hits	123
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

LCE1C_HUMAN
NC score	0.266173 (rank : 273)	θ value	θ > 10 (rank : 761)
Query Neighborhood Hits	557	Target Neighborhood Hits	65	Shared Neighborhood Hits	41
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LYAM3_MOUSE
NC score	0.265737 (rank : 274)	θ value	0.00228821 (rank : 175)
Query Neighborhood Hits	557	Target Neighborhood Hits	390	Shared Neighborhood Hits	185
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

TNR16_MOUSE
NC score	0.264570 (rank : 275)	θ value	0.279714 (rank : 319)
Query Neighborhood Hits	557	Target Neighborhood Hits	178	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

LYAM2_HUMAN
NC score	0.262735 (rank : 276)	θ value	0.00509761 (rank : 189)
Query Neighborhood Hits	557	Target Neighborhood Hits	394	Shared Neighborhood Hits	188
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

TSP2_HUMAN
NC score	0.262651 (rank : 277)	θ value	2.36792 (rank : 434)
Query Neighborhood Hits	557	Target Neighborhood Hits	359	Shared Neighborhood Hits	189
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

MUC13_MOUSE
NC score	0.259583 (rank : 278)	θ value	θ > 10 (rank : 826)
Query Neighborhood Hits	557	Target Neighborhood Hits	447	Shared Neighborhood Hits	196
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

ZAN_HUMAN
NC score	0.255966 (rank : 279)	θ value	θ > 10 (rank : 988)
Query Neighborhood Hits	557	Target Neighborhood Hits	679	Shared Neighborhood Hits	269
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ESM1_MOUSE
NC score	0.254317 (rank : 280)	θ value	1.06291 (rank : 369)
Query Neighborhood Hits	557	Target Neighborhood Hits	107	Shared Neighborhood Hits	62
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

HMCN1_HUMAN
NC score	0.253720 (rank : 281)	θ value	θ > 10 (rank : 726)
Query Neighborhood Hits	557	Target Neighborhood Hits	983	Shared Neighborhood Hits	243
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

LYAM3_HUMAN
NC score	0.252075 (rank : 282)	θ value	0.0252991 (rank : 235)
Query Neighborhood Hits	557	Target Neighborhood Hits	378	Shared Neighborhood Hits	182
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

SORL_HUMAN
NC score	0.251502 (rank : 283)	θ value	0.00390308 (rank : 185)
Query Neighborhood Hits	557	Target Neighborhood Hits	440	Shared Neighborhood Hits	202
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

TDGF1_MOUSE
NC score	0.251482 (rank : 284)	θ value	θ > 10 (rank : 918)
Query Neighborhood Hits	557	Target Neighborhood Hits	146	Shared Neighborhood Hits	115
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

KRA44_HUMAN
NC score	0.250376 (rank : 285)	θ value	θ > 10 (rank : 750)
Query Neighborhood Hits	557	Target Neighborhood Hits	162	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

LCE1B_HUMAN
NC score	0.249007 (rank : 286)	θ value	θ > 10 (rank : 760)
Query Neighborhood Hits	557	Target Neighborhood Hits	58	Shared Neighborhood Hits	40
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

TNR4_HUMAN
NC score	0.244618 (rank : 287)	θ value	θ > 10 (rank : 945)
Query Neighborhood Hits	557	Target Neighborhood Hits	152	Shared Neighborhood Hits	92
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

MKS3_MOUSE
NC score	0.244556 (rank : 288)	θ value	0.00665767 (rank : 194)
Query Neighborhood Hits	557	Target Neighborhood Hits	89	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

KRA15_HUMAN
NC score	0.243128 (rank : 289)	θ value	5.27518 (rank : 497)
Query Neighborhood Hits	557	Target Neighborhood Hits	126	Shared Neighborhood Hits	82
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

TIE1_HUMAN
NC score	0.237346 (rank : 290)	θ value	6.87365e-08 (rank : 91)
Query Neighborhood Hits	557	Target Neighborhood Hits	1241	Shared Neighborhood Hits	258
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TNR23_MOUSE
NC score	0.236386 (rank : 291)	θ value	0.0431538 (rank : 249)
Query Neighborhood Hits	557	Target Neighborhood Hits	114	Shared Neighborhood Hits	78
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

MUC2_HUMAN
NC score	0.236330 (rank : 292)	θ value	0.47712 (rank : 346)
Query Neighborhood Hits	557	Target Neighborhood Hits	906	Shared Neighborhood Hits	293
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

VWF_HUMAN
NC score	0.235660 (rank : 293)	θ value	θ > 10 (rank : 970)
Query Neighborhood Hits	557	Target Neighborhood Hits	396	Shared Neighborhood Hits	195
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

HABP2_HUMAN
NC score	0.235065 (rank : 294)	θ value	2.36792 (rank : 426)
Query Neighborhood Hits	557	Target Neighborhood Hits	431	Shared Neighborhood Hits	202
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

CFC1_MOUSE
NC score	0.233605 (rank : 295)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	557	Target Neighborhood Hits	125	Shared Neighborhood Hits	104
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

KR412_HUMAN
NC score	0.233450 (rank : 296)	θ value	θ > 10 (rank : 745)
Query Neighborhood Hits	557	Target Neighborhood Hits	178	Shared Neighborhood Hits	107
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

HABP2_MOUSE
NC score	0.231103 (rank : 297)	θ value	θ > 10 (rank : 722)
Query Neighborhood Hits	557	Target Neighborhood Hits	445	Shared Neighborhood Hits	199
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

TIE1_MOUSE
NC score	0.230307 (rank : 298)	θ value	7.59969e-07 (rank : 103)
Query Neighborhood Hits	557	Target Neighborhood Hits	1266	Shared Neighborhood Hits	252
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

LYAM1_HUMAN
NC score	0.230216 (rank : 299)	θ value	0.279714 (rank : 314)
Query Neighborhood Hits	557	Target Neighborhood Hits	315	Shared Neighborhood Hits	153
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

TNR25_HUMAN
NC score	0.228993 (rank : 300)	θ value	θ > 10 (rank : 941)
Query Neighborhood Hits	557	Target Neighborhood Hits	172	Shared Neighborhood Hits	99
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

ELTD1_HUMAN
NC score	0.224498 (rank : 301)	θ value	0.0431538 (rank : 243)
Query Neighborhood Hits	557	Target Neighborhood Hits	269	Shared Neighborhood Hits	143
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

KRA99_HUMAN
NC score	0.224469 (rank : 302)	θ value	θ > 10 (rank : 758)
Query Neighborhood Hits	557	Target Neighborhood Hits	173	Shared Neighborhood Hits	109
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

LYAM1_MOUSE
NC score	0.223381 (rank : 303)	θ value	θ > 10 (rank : 794)
Query Neighborhood Hits	557	Target Neighborhood Hits	332	Shared Neighborhood Hits	156
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

MT3_HUMAN
NC score	0.222653 (rank : 304)	θ value	θ > 10 (rank : 822)
Query Neighborhood Hits	557	Target Neighborhood Hits	82	Shared Neighborhood Hits	49
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

CNTP2_MOUSE
NC score	0.221020 (rank : 305)	θ value	θ > 10 (rank : 627)
Query Neighborhood Hits	557	Target Neighborhood Hits	194	Shared Neighborhood Hits	113
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

FAT2_HUMAN
NC score	0.218936 (rank : 306)	θ value	0.00869519 (rank : 197)
Query Neighborhood Hits	557	Target Neighborhood Hits	507	Shared Neighborhood Hits	187
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

CNTP2_HUMAN
NC score	0.217694 (rank : 307)	θ value	θ > 10 (rank : 626)
Query Neighborhood Hits	557	Target Neighborhood Hits	199	Shared Neighborhood Hits	114
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

TNR14_HUMAN
NC score	0.216019 (rank : 308)	θ value	0.0252991 (rank : 238)
Query Neighborhood Hits	557	Target Neighborhood Hits	149	Shared Neighborhood Hits	95
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

VWF_MOUSE
NC score	0.214175 (rank : 309)	θ value	0.163984 (rank : 298)
Query Neighborhood Hits	557	Target Neighborhood Hits	381	Shared Neighborhood Hits	180
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

TIE2_MOUSE
NC score	0.213122 (rank : 310)	θ value	4.45536e-07 (rank : 100)
Query Neighborhood Hits	557	Target Neighborhood Hits	1204	Shared Neighborhood Hits	252
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

CNTP4_HUMAN
NC score	0.212520 (rank : 311)	θ value	θ > 10 (rank : 629)
Query Neighborhood Hits	557	Target Neighborhood Hits	187	Shared Neighborhood Hits	101
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

TIE2_HUMAN
NC score	0.210779 (rank : 312)	θ value	7.59969e-07 (rank : 104)
Query Neighborhood Hits	557	Target Neighborhood Hits	1192	Shared Neighborhood Hits	243
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

KR410_HUMAN
NC score	0.210658 (rank : 313)	θ value	θ > 10 (rank : 744)
Query Neighborhood Hits	557	Target Neighborhood Hits	156	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

CNTP4_MOUSE
NC score	0.208282 (rank : 314)	θ value	θ > 10 (rank : 630)
Query Neighborhood Hits	557	Target Neighborhood Hits	193	Shared Neighborhood Hits	110
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

TEFF2_MOUSE
NC score	0.207830 (rank : 315)	θ value	θ > 10 (rank : 923)
Query Neighborhood Hits	557	Target Neighborhood Hits	214	Shared Neighborhood Hits	114
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TEFF2_HUMAN
NC score	0.205284 (rank : 316)	θ value	θ > 10 (rank : 922)
Query Neighborhood Hits	557	Target Neighborhood Hits	211	Shared Neighborhood Hits	115
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

LCE1D_HUMAN
NC score	0.202367 (rank : 317)	θ value	θ > 10 (rank : 762)
Query Neighborhood Hits	557	Target Neighborhood Hits	44	Shared Neighborhood Hits	29
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

TDGF1_HUMAN
NC score	0.201397 (rank : 318)	θ value	θ > 10 (rank : 917)
Query Neighborhood Hits	557	Target Neighborhood Hits	132	Shared Neighborhood Hits	102
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

MKS3_HUMAN
NC score	0.197545 (rank : 319)	θ value	0.00228821 (rank : 176)
Query Neighborhood Hits	557	Target Neighborhood Hits	79	Shared Neighborhood Hits	68
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

TNR9_MOUSE
NC score	0.197237 (rank : 320)	θ value	1.81305 (rank : 414)
Query Neighborhood Hits	557	Target Neighborhood Hits	137	Shared Neighborhood Hits	80
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TNR22_MOUSE
NC score	0.197168 (rank : 321)	θ value	2.36792 (rank : 433)
Query Neighborhood Hits	557	Target Neighborhood Hits	97	Shared Neighborhood Hits	62
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TDGF2_HUMAN
NC score	0.196935 (rank : 322)	θ value	θ > 10 (rank : 919)
Query Neighborhood Hits	557	Target Neighborhood Hits	131	Shared Neighborhood Hits	99
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

MUC13_HUMAN
NC score	0.194001 (rank : 323)	θ value	0.00509761 (rank : 190)
Query Neighborhood Hits	557	Target Neighborhood Hits	164	Shared Neighborhood Hits	102
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

TNR7_HUMAN
NC score	0.192990 (rank : 324)	θ value	1.38821 (rank : 394)
Query Neighborhood Hits	557	Target Neighborhood Hits	120	Shared Neighborhood Hits	76
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

LCE1A_HUMAN
NC score	0.192676 (rank : 325)	θ value	θ > 10 (rank : 759)
Query Neighborhood Hits	557	Target Neighborhood Hits	47	Shared Neighborhood Hits	30
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LCE1F_HUMAN
NC score	0.192216 (rank : 326)	θ value	θ > 10 (rank : 764)
Query Neighborhood Hits	557	Target Neighborhood Hits	48	Shared Neighborhood Hits	29
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

PGCB_MOUSE
NC score	0.190040 (rank : 327)	θ value	θ > 10 (rank : 859)
Query Neighborhood Hits	557	Target Neighborhood Hits	459	Shared Neighborhood Hits	161
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

LCE1E_HUMAN
NC score	0.188519 (rank : 328)	θ value	θ > 10 (rank : 763)
Query Neighborhood Hits	557	Target Neighborhood Hits	53	Shared Neighborhood Hits	30
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

CNTP3_HUMAN
NC score	0.187830 (rank : 329)	θ value	θ > 10 (rank : 628)
Query Neighborhood Hits	557	Target Neighborhood Hits	195	Shared Neighborhood Hits	105
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

KRA24_HUMAN
NC score	0.185600 (rank : 330)	θ value	0.47712 (rank : 345)
Query Neighborhood Hits	557	Target Neighborhood Hits	192	Shared Neighborhood Hits	95
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

CNTP1_HUMAN
NC score	0.185269 (rank : 331)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	557	Target Neighborhood Hits	196	Shared Neighborhood Hits	108
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

MT1X_HUMAN
NC score	0.185227 (rank : 332)	θ value	θ > 10 (rank : 818)
Query Neighborhood Hits	557	Target Neighborhood Hits	76	Shared Neighborhood Hits	50
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

MT4_MOUSE
NC score	0.185040 (rank : 333)	θ value	θ > 10 (rank : 825)
Query Neighborhood Hits	557	Target Neighborhood Hits	102	Shared Neighborhood Hits	65
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

PGCB_HUMAN
NC score	0.184594 (rank : 334)	θ value	θ > 10 (rank : 858)
Query Neighborhood Hits	557	Target Neighborhood Hits	478	Shared Neighborhood Hits	171
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

LCE3A_HUMAN
NC score	0.183437 (rank : 335)	θ value	θ > 10 (rank : 769)
Query Neighborhood Hits	557	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

CNTP1_MOUSE
NC score	0.182421 (rank : 336)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	557	Target Neighborhood Hits	183	Shared Neighborhood Hits	103
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

KRA42_HUMAN
NC score	0.178711 (rank : 337)	θ value	θ > 10 (rank : 749)
Query Neighborhood Hits	557	Target Neighborhood Hits	149	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

RELN_MOUSE
NC score	0.178492 (rank : 338)	θ value	θ > 10 (rank : 880)
Query Neighborhood Hits	557	Target Neighborhood Hits	235	Shared Neighborhood Hits	153
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

RELN_HUMAN
NC score	0.174262 (rank : 339)	θ value	θ > 10 (rank : 879)
Query Neighborhood Hits	557	Target Neighborhood Hits	233	Shared Neighborhood Hits	152
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

BMPER_MOUSE
NC score	0.173705 (rank : 340)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	557	Target Neighborhood Hits	194	Shared Neighborhood Hits	112
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

LCE2A_HUMAN
NC score	0.171886 (rank : 341)	θ value	θ > 10 (rank : 765)
Query Neighborhood Hits	557	Target Neighborhood Hits	50	Shared Neighborhood Hits	28
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

HGFA_HUMAN
NC score	0.168916 (rank : 342)	θ value	θ > 10 (rank : 725)
Query Neighborhood Hits	557	Target Neighborhood Hits	436	Shared Neighborhood Hits	182
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

PGCA_HUMAN
NC score	0.168066 (rank : 343)	θ value	0.0148317 (rank : 212)
Query Neighborhood Hits	557	Target Neighborhood Hits	821	Shared Neighborhood Hits	205
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

MT1A_HUMAN
NC score	0.167386 (rank : 344)	θ value	θ > 10 (rank : 809)
Query Neighborhood Hits	557	Target Neighborhood Hits	74	Shared Neighborhood Hits	46
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

SHBG_HUMAN
NC score	0.165773 (rank : 345)	θ value	θ > 10 (rank : 899)
Query Neighborhood Hits	557	Target Neighborhood Hits	45	Shared Neighborhood Hits	25
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

LCE2C_HUMAN
NC score	0.163976 (rank : 346)	θ value	θ > 10 (rank : 767)
Query Neighborhood Hits	557	Target Neighborhood Hits	53	Shared Neighborhood Hits	30
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

FA10_MOUSE
NC score	0.163637 (rank : 347)	θ value	0.125558 (rank : 288)
Query Neighborhood Hits	557	Target Neighborhood Hits	435	Shared Neighborhood Hits	182
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

LCE2D_HUMAN
NC score	0.163287 (rank : 348)	θ value	θ > 10 (rank : 768)
Query Neighborhood Hits	557	Target Neighborhood Hits	50	Shared Neighborhood Hits	28
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

BMPER_HUMAN
NC score	0.162841 (rank : 349)	θ value	0.47712 (rank : 339)
Query Neighborhood Hits	557	Target Neighborhood Hits	175	Shared Neighborhood Hits	95
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

LCE2B_HUMAN
NC score	0.162153 (rank : 350)	θ value	θ > 10 (rank : 766)
Query Neighborhood Hits	557	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

PROC_MOUSE
NC score	0.161213 (rank : 351)	θ value	0.00869519 (rank : 200)
Query Neighborhood Hits	557	Target Neighborhood Hits	426	Shared Neighborhood Hits	181
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

HGFA_MOUSE
NC score	0.160168 (rank : 352)	θ value	3.0926 (rank : 447)
Query Neighborhood Hits	557	Target Neighborhood Hits	419	Shared Neighborhood Hits	177
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

EMR3_HUMAN
NC score	0.159862 (rank : 353)	θ value	θ > 10 (rank : 673)
Query Neighborhood Hits	557	Target Neighborhood Hits	245	Shared Neighborhood Hits	114
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

FA10_HUMAN
NC score	0.159286 (rank : 354)	θ value	8.99809 (rank : 545)
Query Neighborhood Hits	557	Target Neighborhood Hits	431	Shared Neighborhood Hits	177
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

SHBG_MOUSE
NC score	0.158564 (rank : 355)	θ value	θ > 10 (rank : 900)
Query Neighborhood Hits	557	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	P97497	Gene names	Shbg
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP).

TNR3_HUMAN
NC score	0.156432 (rank : 356)	θ value	9.29e-05 (rank : 135)
Query Neighborhood Hits	557	Target Neighborhood Hits	145	Shared Neighborhood Hits	76
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

CO6_HUMAN
NC score	0.155361 (rank : 357)	θ value	4.03905 (rank : 466)
Query Neighborhood Hits	557	Target Neighborhood Hits	331	Shared Neighborhood Hits	131
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

TNR3_MOUSE
NC score	0.154944 (rank : 358)	θ value	θ > 10 (rank : 944)
Query Neighborhood Hits	557	Target Neighborhood Hits	113	Shared Neighborhood Hits	76
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

MT4_HUMAN
NC score	0.153386 (rank : 359)	θ value	θ > 10 (rank : 824)
Query Neighborhood Hits	557	Target Neighborhood Hits	83	Shared Neighborhood Hits	50
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

FA9_HUMAN
NC score	0.151988 (rank : 360)	θ value	θ > 10 (rank : 687)
Query Neighborhood Hits	557	Target Neighborhood Hits	421	Shared Neighborhood Hits	170
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

MMRN1_HUMAN
NC score	0.151987 (rank : 361)	θ value	θ > 10 (rank : 808)
Query Neighborhood Hits	557	Target Neighborhood Hits	636	Shared Neighborhood Hits	124
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

MT2_MOUSE
NC score	0.148405 (rank : 362)	θ value	θ > 10 (rank : 821)
Query Neighborhood Hits	557	Target Neighborhood Hits	81	Shared Neighborhood Hits	48
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

FA12_HUMAN
NC score	0.144918 (rank : 363)	θ value	θ > 10 (rank : 684)
Query Neighborhood Hits	557	Target Neighborhood Hits	425	Shared Neighborhood Hits	177
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

ADA11_HUMAN
NC score	0.144356 (rank : 364)	θ value	0.47712 (rank : 337)
Query Neighborhood Hits	557	Target Neighborhood Hits	259	Shared Neighborhood Hits	159
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA11_MOUSE
NC score	0.144197 (rank : 365)	θ value	0.47712 (rank : 338)
Query Neighborhood Hits	557	Target Neighborhood Hits	263	Shared Neighborhood Hits	159
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

RECK_HUMAN
NC score	0.143968 (rank : 366)	θ value	θ > 10 (rank : 877)
Query Neighborhood Hits	557	Target Neighborhood Hits	189	Shared Neighborhood Hits	97
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

LCE4A_HUMAN
NC score	0.143950 (rank : 367)	θ value	θ > 10 (rank : 773)
Query Neighborhood Hits	557	Target Neighborhood Hits	26	Shared Neighborhood Hits	15
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

FA7_HUMAN
NC score	0.143875 (rank : 368)	θ value	θ > 10 (rank : 685)
Query Neighborhood Hits	557	Target Neighborhood Hits	404	Shared Neighborhood Hits	169
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

TNR8_HUMAN
NC score	0.143333 (rank : 369)	θ value	4.03905 (rank : 484)
Query Neighborhood Hits	557	Target Neighborhood Hits	198	Shared Neighborhood Hits	95
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

CT127_HUMAN
NC score	0.142733 (rank : 370)	θ value	θ > 10 (rank : 656)
Query Neighborhood Hits	557	Target Neighborhood Hits	67	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

TNR5_MOUSE
NC score	0.142025 (rank : 371)	θ value	θ > 10 (rank : 946)
Query Neighborhood Hits	557	Target Neighborhood Hits	131	Shared Neighborhood Hits	84
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

FSTL3_HUMAN
NC score	0.141281 (rank : 372)	θ value	θ > 10 (rank : 694)
Query Neighborhood Hits	557	Target Neighborhood Hits	162	Shared Neighborhood Hits	87
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

PERT_HUMAN
NC score	0.140507 (rank : 373)	θ value	θ > 10 (rank : 855)
Query Neighborhood Hits	557	Target Neighborhood Hits	221	Shared Neighborhood Hits	114
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

TNR9_HUMAN
NC score	0.139860 (rank : 374)	θ value	θ > 10 (rank : 951)
Query Neighborhood Hits	557	Target Neighborhood Hits	166	Shared Neighborhood Hits	103
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

ADA15_MOUSE
NC score	0.139789 (rank : 375)	θ value	θ > 10 (rank : 564)
Query Neighborhood Hits	557	Target Neighborhood Hits	324	Shared Neighborhood Hits	199
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

MT1H_HUMAN
NC score	0.138991 (rank : 376)	θ value	θ > 10 (rank : 814)
Query Neighborhood Hits	557	Target Neighborhood Hits	78	Shared Neighborhood Hits	48
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

MT1B_HUMAN
NC score	0.138248 (rank : 377)	θ value	θ > 10 (rank : 810)
Query Neighborhood Hits	557	Target Neighborhood Hits	87	Shared Neighborhood Hits	50
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

LRP10_HUMAN
NC score	0.138084 (rank : 378)	θ value	θ > 10 (rank : 782)
Query Neighborhood Hits	557	Target Neighborhood Hits	197	Shared Neighborhood Hits	79
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

TNR7_MOUSE
NC score	0.137829 (rank : 379)	θ value	θ > 10 (rank : 949)
Query Neighborhood Hits	557	Target Neighborhood Hits	112	Shared Neighborhood Hits	61
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

TNR19_MOUSE
NC score	0.137181 (rank : 380)	θ value	θ > 10 (rank : 936)
Query Neighborhood Hits	557	Target Neighborhood Hits	100	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR8_MOUSE
NC score	0.135285 (rank : 381)	θ value	θ > 10 (rank : 950)
Query Neighborhood Hits	557	Target Neighborhood Hits	208	Shared Neighborhood Hits	93
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

LRP10_MOUSE
NC score	0.134835 (rank : 382)	θ value	θ > 10 (rank : 783)
Query Neighborhood Hits	557	Target Neighborhood Hits	169	Shared Neighborhood Hits	73
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LORI_MOUSE
NC score	0.134524 (rank : 383)	θ value	θ > 10 (rank : 778)
Query Neighborhood Hits	557	Target Neighborhood Hits	47	Shared Neighborhood Hits	20
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

VEGFC_HUMAN
NC score	0.134318 (rank : 384)	θ value	2.36792 (rank : 435)
Query Neighborhood Hits	557	Target Neighborhood Hits	128	Shared Neighborhood Hits	83
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

ADAM8_MOUSE
NC score	0.134277 (rank : 385)	θ value	θ > 10 (rank : 578)
Query Neighborhood Hits	557	Target Neighborhood Hits	326	Shared Neighborhood Hits	177
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

MCSP_MOUSE
NC score	0.134256 (rank : 386)	θ value	θ > 10 (rank : 802)
Query Neighborhood Hits	557	Target Neighborhood Hits	108	Shared Neighborhood Hits	50
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MT1_MOUSE
NC score	0.133948 (rank : 387)	θ value	θ > 10 (rank : 819)
Query Neighborhood Hits	557	Target Neighborhood Hits	72	Shared Neighborhood Hits	38
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

TNR26_MOUSE
NC score	0.133735 (rank : 388)	θ value	1.38821 (rank : 393)
Query Neighborhood Hits	557	Target Neighborhood Hits	106	Shared Neighborhood Hits	71
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

MUC7_HUMAN
NC score	0.133514 (rank : 389)	θ value	θ > 10 (rank : 827)
Query Neighborhood Hits	557	Target Neighborhood Hits	538	Shared Neighborhood Hits	137
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

PROC_HUMAN
NC score	0.132833 (rank : 390)	θ value	θ > 10 (rank : 871)
Query Neighborhood Hits	557	Target Neighborhood Hits	406	Shared Neighborhood Hits	174
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

ADAM8_HUMAN
NC score	0.132809 (rank : 391)	θ value	8.99809 (rank : 539)
Query Neighborhood Hits	557	Target Neighborhood Hits	327	Shared Neighborhood Hits	184
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

FSTL3_MOUSE
NC score	0.132606 (rank : 392)	θ value	θ > 10 (rank : 695)
Query Neighborhood Hits	557	Target Neighborhood Hits	152	Shared Neighborhood Hits	81
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

ADA15_HUMAN
NC score	0.132372 (rank : 393)	θ value	θ > 10 (rank : 563)
Query Neighborhood Hits	557	Target Neighborhood Hits	288	Shared Neighborhood Hits	171
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

ADA23_HUMAN
NC score	0.131408 (rank : 394)	θ value	3.0926 (rank : 439)
Query Neighborhood Hits	557	Target Neighborhood Hits	235	Shared Neighborhood Hits	147
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

TNR6_MOUSE
NC score	0.129484 (rank : 395)	θ value	1.81305 (rank : 413)
Query Neighborhood Hits	557	Target Neighborhood Hits	99	Shared Neighborhood Hits	63
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

ADA23_MOUSE
NC score	0.128346 (rank : 396)	θ value	1.81305 (rank : 396)
Query Neighborhood Hits	557	Target Neighborhood Hits	245	Shared Neighborhood Hits	153
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

TNR11_HUMAN
NC score	0.128293 (rank : 397)	θ value	θ > 10 (rank : 932)
Query Neighborhood Hits	557	Target Neighborhood Hits	135	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

LRP6_HUMAN
NC score	0.127780 (rank : 398)	θ value	θ > 10 (rank : 791)
Query Neighborhood Hits	557	Target Neighborhood Hits	235	Shared Neighborhood Hits	106
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

CORIN_HUMAN
NC score	0.127776 (rank : 399)	θ value	1.38821 (rank : 382)
Query Neighborhood Hits	557	Target Neighborhood Hits	453	Shared Neighborhood Hits	159
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

VEGFC_MOUSE
NC score	0.126886 (rank : 400)	θ value	θ > 10 (rank : 967)
Query Neighborhood Hits	557	Target Neighborhood Hits	119	Shared Neighborhood Hits	80
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

PERT_MOUSE
NC score	0.125986 (rank : 401)	θ value	θ > 10 (rank : 856)
Query Neighborhood Hits	557	Target Neighborhood Hits	221	Shared Neighborhood Hits	111
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

TECTA_MOUSE
NC score	0.125393 (rank : 402)	θ value	θ > 10 (rank : 921)
Query Neighborhood Hits	557	Target Neighborhood Hits	244	Shared Neighborhood Hits	142
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

LRP6_MOUSE
NC score	0.125074 (rank : 403)	θ value	θ > 10 (rank : 792)
Query Neighborhood Hits	557	Target Neighborhood Hits	232	Shared Neighborhood Hits	104
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

CRAC1_MOUSE
NC score	0.125045 (rank : 404)	θ value	θ > 10 (rank : 647)
Query Neighborhood Hits	557	Target Neighborhood Hits	112	Shared Neighborhood Hits	70
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

LRP5_MOUSE
NC score	0.124837 (rank : 405)	θ value	θ > 10 (rank : 790)
Query Neighborhood Hits	557	Target Neighborhood Hits	236	Shared Neighborhood Hits	113
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

KR122_HUMAN
NC score	0.124598 (rank : 406)	θ value	θ > 10 (rank : 735)
Query Neighborhood Hits	557	Target Neighborhood Hits	97	Shared Neighborhood Hits	54
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

CRAC1_HUMAN
NC score	0.123297 (rank : 407)	θ value	θ > 10 (rank : 646)
Query Neighborhood Hits	557	Target Neighborhood Hits	111	Shared Neighborhood Hits	68
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

RECK_MOUSE
NC score	0.123228 (rank : 408)	θ value	θ > 10 (rank : 878)
Query Neighborhood Hits	557	Target Neighborhood Hits	158	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

ADA19_MOUSE
NC score	0.122299 (rank : 409)	θ value	0.279714 (rank : 309)
Query Neighborhood Hits	557	Target Neighborhood Hits	315	Shared Neighborhood Hits	179
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

CO7_HUMAN
NC score	0.122221 (rank : 410)	θ value	θ > 10 (rank : 632)
Query Neighborhood Hits	557	Target Neighborhood Hits	278	Shared Neighborhood Hits	114
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

UROL1_MOUSE
NC score	0.120961 (rank : 411)	θ value	θ > 10 (rank : 963)
Query Neighborhood Hits	557	Target Neighborhood Hits	235	Shared Neighborhood Hits	113
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

EMR4_MOUSE
NC score	0.120757 (rank : 412)	θ value	θ > 10 (rank : 674)
Query Neighborhood Hits	557	Target Neighborhood Hits	191	Shared Neighborhood Hits	88
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

ADA22_MOUSE
NC score	0.120694 (rank : 413)	θ value	0.00035302 (rank : 153)
Query Neighborhood Hits	557	Target Neighborhood Hits	225	Shared Neighborhood Hits	117
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

FA7_MOUSE
NC score	0.120102 (rank : 414)	θ value	θ > 10 (rank : 686)
Query Neighborhood Hits	557	Target Neighborhood Hits	374	Shared Neighborhood Hits	146
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

RSPO4_HUMAN
NC score	0.119096 (rank : 415)	θ value	θ > 10 (rank : 884)
Query Neighborhood Hits	557	Target Neighborhood Hits	110	Shared Neighborhood Hits	66
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

TNR1B_HUMAN
NC score	0.119073 (rank : 416)	θ value	0.0193708 (rank : 224)
Query Neighborhood Hits	557	Target Neighborhood Hits	127	Shared Neighborhood Hits	77
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

NRG2_MOUSE
NC score	0.118968 (rank : 417)	θ value	θ > 10 (rank : 835)
Query Neighborhood Hits	557	Target Neighborhood Hits	392	Shared Neighborhood Hits	101
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

LRP5_HUMAN
NC score	0.118705 (rank : 418)	θ value	θ > 10 (rank : 789)
Query Neighborhood Hits	557	Target Neighborhood Hits	224	Shared Neighborhood Hits	104
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

SMDF_HUMAN
NC score	0.118397 (rank : 419)	θ value	θ > 10 (rank : 901)
Query Neighborhood Hits	557	Target Neighborhood Hits	117	Shared Neighborhood Hits	65
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

LRP3_HUMAN
NC score	0.118261 (rank : 420)	θ value	θ > 10 (rank : 786)
Query Neighborhood Hits	557	Target Neighborhood Hits	280	Shared Neighborhood Hits	108
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

KR413_HUMAN
NC score	0.118004 (rank : 421)	θ value	θ > 10 (rank : 746)
Query Neighborhood Hits	557	Target Neighborhood Hits	112	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

TNR5_HUMAN
NC score	0.116384 (rank : 422)	θ value	8.99809 (rank : 556)
Query Neighborhood Hits	557	Target Neighborhood Hits	102	Shared Neighborhood Hits	69
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TNR19_HUMAN
NC score	0.116066 (rank : 423)	θ value	θ > 10 (rank : 935)
Query Neighborhood Hits	557	Target Neighborhood Hits	89	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

ADA33_HUMAN
NC score	0.115761 (rank : 424)	θ value	3.0926 (rank : 440)
Query Neighborhood Hits	557	Target Neighborhood Hits	264	Shared Neighborhood Hits	146
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA19_HUMAN
NC score	0.115605 (rank : 425)	θ value	2.36792 (rank : 417)
Query Neighborhood Hits	557	Target Neighborhood Hits	381	Shared Neighborhood Hits	171
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

MFGM_HUMAN
NC score	0.115539 (rank : 426)	θ value	θ > 10 (rank : 806)
Query Neighborhood Hits	557	Target Neighborhood Hits	150	Shared Neighborhood Hits	93
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

RSPO4_MOUSE
NC score	0.114930 (rank : 427)	θ value	θ > 10 (rank : 885)
Query Neighborhood Hits	557	Target Neighborhood Hits	110	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

RSPO3_HUMAN
NC score	0.114720 (rank : 428)	θ value	1.38821 (rank : 389)
Query Neighborhood Hits	557	Target Neighborhood Hits	128	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

KR241_HUMAN
NC score	0.114682 (rank : 429)	θ value	θ > 10 (rank : 742)
Query Neighborhood Hits	557	Target Neighborhood Hits	71	Shared Neighborhood Hits	45
SwissProt Accessions	Q3LI83	Gene names	KRTAP24-1, KAP24.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 24-1.

TARSH_HUMAN
NC score	0.114326 (rank : 430)	θ value	0.00102713 (rank : 165)
Query Neighborhood Hits	557	Target Neighborhood Hits	768	Shared Neighborhood Hits	126
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

PGH2_MOUSE
NC score	0.113925 (rank : 431)	θ value	θ > 10 (rank : 863)
Query Neighborhood Hits	557	Target Neighborhood Hits	113	Shared Neighborhood Hits	76
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

CORIN_MOUSE
NC score	0.113244 (rank : 432)	θ value	θ > 10 (rank : 643)
Query Neighborhood Hits	557	Target Neighborhood Hits	451	Shared Neighborhood Hits	158
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

ADAM9_MOUSE
NC score	0.113168 (rank : 433)	θ value	θ > 10 (rank : 580)
Query Neighborhood Hits	557	Target Neighborhood Hits	325	Shared Neighborhood Hits	152
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

KR124_HUMAN
NC score	0.112864 (rank : 434)	θ value	θ > 10 (rank : 737)
Query Neighborhood Hits	557	Target Neighborhood Hits	124	Shared Neighborhood Hits	71
SwissProt Accessions	P60329	Gene names	KRTAP12-4, KAP12.4, KRTAP12.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-4 (Keratin-associated protein 12.4) (High sulfur keratin-associated protein 12.4).

CK024_HUMAN
NC score	0.112396 (rank : 435)	θ value	0.21417 (rank : 299)
Query Neighborhood Hits	557	Target Neighborhood Hits	408	Shared Neighborhood Hits	81
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

TNR6B_HUMAN
NC score	0.111967 (rank : 436)	θ value	θ > 10 (rank : 947)
Query Neighborhood Hits	557	Target Neighborhood Hits	103	Shared Neighborhood Hits	65
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

PRG4_HUMAN
NC score	0.111750 (rank : 437)	θ value	8.99809 (rank : 553)
Query Neighborhood Hits	557	Target Neighborhood Hits	764	Shared Neighborhood Hits	160
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

TECTA_HUMAN
NC score	0.111463 (rank : 438)	θ value	θ > 10 (rank : 920)
Query Neighborhood Hits	557	Target Neighborhood Hits	239	Shared Neighborhood Hits	128
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

NRG1_HUMAN
NC score	0.111331 (rank : 439)	θ value	θ > 10 (rank : 833)
Query Neighborhood Hits	557	Target Neighborhood Hits	285	Shared Neighborhood Hits	81
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

LCE5A_HUMAN
NC score	0.110921 (rank : 440)	θ value	θ > 10 (rank : 774)
Query Neighborhood Hits	557	Target Neighborhood Hits	43	Shared Neighborhood Hits	23
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

ADAM7_HUMAN
NC score	0.110693 (rank : 441)	θ value	2.36792 (rank : 418)
Query Neighborhood Hits	557	Target Neighborhood Hits	221	Shared Neighborhood Hits	138
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

TNR11_MOUSE
NC score	0.110055 (rank : 442)	θ value	θ > 10 (rank : 933)
Query Neighborhood Hits	557	Target Neighborhood Hits	121	Shared Neighborhood Hits	72
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

APR3_MOUSE
NC score	0.109488 (rank : 443)	θ value	θ > 10 (rank : 584)
Query Neighborhood Hits	557	Target Neighborhood Hits	61	Shared Neighborhood Hits	51
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

CLC14_MOUSE
NC score	0.109130 (rank : 444)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	557	Target Neighborhood Hits	120	Shared Neighborhood Hits	73
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

PRP2_MOUSE
NC score	0.108668 (rank : 445)	θ value	θ > 10 (rank : 873)
Query Neighborhood Hits	557	Target Neighborhood Hits	347	Shared Neighborhood Hits	82
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

BMP1_MOUSE
NC score	0.108154 (rank : 446)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	557	Target Neighborhood Hits	236	Shared Neighborhood Hits	115
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

VASN_HUMAN
NC score	0.108132 (rank : 447)	θ value	θ > 10 (rank : 966)
Query Neighborhood Hits	557	Target Neighborhood Hits	449	Shared Neighborhood Hits	120
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

TNR1A_MOUSE
NC score	0.107769 (rank : 448)	θ value	0.279714 (rank : 320)
Query Neighborhood Hits	557	Target Neighborhood Hits	131	Shared Neighborhood Hits	64
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

ADA22_HUMAN
NC score	0.107553 (rank : 449)	θ value	0.00228821 (rank : 173)
Query Neighborhood Hits	557	Target Neighborhood Hits	211	Shared Neighborhood Hits	111
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

BMP1_HUMAN
NC score	0.107230 (rank : 450)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	557	Target Neighborhood Hits	233	Shared Neighborhood Hits	114
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

TLL1_MOUSE
NC score	0.107009 (rank : 451)	θ value	θ > 10 (rank : 927)
Query Neighborhood Hits	557	Target Neighborhood Hits	237	Shared Neighborhood Hits	112
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

UROL1_HUMAN
NC score	0.106974 (rank : 452)	θ value	θ > 10 (rank : 962)
Query Neighborhood Hits	557	Target Neighborhood Hits	213	Shared Neighborhood Hits	102
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

CLC14_HUMAN
NC score	0.106745 (rank : 453)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	557	Target Neighborhood Hits	143	Shared Neighborhood Hits	80
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

WFDC3_HUMAN
NC score	0.106348 (rank : 454)	θ value	θ > 10 (rank : 984)
Query Neighborhood Hits	557	Target Neighborhood Hits	138	Shared Neighborhood Hits	63
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

CHRD_MOUSE
NC score	0.105883 (rank : 455)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	557	Target Neighborhood Hits	102	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

ADA33_MOUSE
NC score	0.105401 (rank : 456)	θ value	8.99809 (rank : 538)
Query Neighborhood Hits	557	Target Neighborhood Hits	231	Shared Neighborhood Hits	139
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

CO8B_MOUSE
NC score	0.105387 (rank : 457)	θ value	θ > 10 (rank : 635)
Query Neighborhood Hits	557	Target Neighborhood Hits	224	Shared Neighborhood Hits	94
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

ADAM9_HUMAN
NC score	0.105223 (rank : 458)	θ value	θ > 10 (rank : 579)
Query Neighborhood Hits	557	Target Neighborhood Hits	243	Shared Neighborhood Hits	134
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

CSPG4_HUMAN
NC score	0.104541 (rank : 459)	θ value	θ > 10 (rank : 654)
Query Neighborhood Hits	557	Target Neighborhood Hits	112	Shared Neighborhood Hits	29
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

ADA10_HUMAN
NC score	0.104402 (rank : 460)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	557	Target Neighborhood Hits	189	Shared Neighborhood Hits	101
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ODFP_MOUSE
NC score	0.103988 (rank : 461)	θ value	θ > 10 (rank : 847)
Query Neighborhood Hits	557	Target Neighborhood Hits	75	Shared Neighborhood Hits	45
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

PRR12_HUMAN
NC score	0.103677 (rank : 462)	θ value	θ > 10 (rank : 874)
Query Neighborhood Hits	557	Target Neighborhood Hits	460	Shared Neighborhood Hits	105
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

TR19L_MOUSE
NC score	0.103252 (rank : 463)	θ value	0.62314 (rank : 356)
Query Neighborhood Hits	557	Target Neighborhood Hits	85	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

TLL1_HUMAN
NC score	0.103174 (rank : 464)	θ value	θ > 10 (rank : 926)
Query Neighborhood Hits	557	Target Neighborhood Hits	236	Shared Neighborhood Hits	108
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

RSPO3_MOUSE
NC score	0.103122 (rank : 465)	θ value	4.03905 (rank : 479)
Query Neighborhood Hits	557	Target Neighborhood Hits	120	Shared Neighborhood Hits	66
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

TLL2_HUMAN
NC score	0.103090 (rank : 466)	θ value	θ > 10 (rank : 928)
Query Neighborhood Hits	557	Target Neighborhood Hits	241	Shared Neighborhood Hits	116
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

ADA18_MOUSE
NC score	0.103003 (rank : 467)	θ value	θ > 10 (rank : 568)
Query Neighborhood Hits	557	Target Neighborhood Hits	227	Shared Neighborhood Hits	132
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

VASN_MOUSE
NC score	0.102682 (rank : 468)	θ value	0.62314 (rank : 357)
Query Neighborhood Hits	557	Target Neighborhood Hits	426	Shared Neighborhood Hits	117
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

MT1E_HUMAN
NC score	0.102437 (rank : 469)	θ value	θ > 10 (rank : 811)
Query Neighborhood Hits	557	Target Neighborhood Hits	75	Shared Neighborhood Hits	47
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

FST_MOUSE
NC score	0.102401 (rank : 470)	θ value	θ > 10 (rank : 697)
Query Neighborhood Hits	557	Target Neighborhood Hits	146	Shared Neighborhood Hits	71
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

PHXR5_MOUSE
NC score	0.102081 (rank : 471)	θ value	θ > 10 (rank : 864)
Query Neighborhood Hits	557	Target Neighborhood Hits	102	Shared Neighborhood Hits	50
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

ADA28_HUMAN
NC score	0.101771 (rank : 472)	θ value	0.0961366 (rank : 273)
Query Neighborhood Hits	557	Target Neighborhood Hits	244	Shared Neighborhood Hits	142
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

CHRD_HUMAN
NC score	0.101580 (rank : 473)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	557	Target Neighborhood Hits	102	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

ADA10_MOUSE
NC score	0.101554 (rank : 474)	θ value	θ > 10 (rank : 560)
Query Neighborhood Hits	557	Target Neighborhood Hits	194	Shared Neighborhood Hits	102
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

NRG4_HUMAN
NC score	0.101442 (rank : 475)	θ value	θ > 10 (rank : 838)
Query Neighborhood Hits	557	Target Neighborhood Hits	85	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

ADA28_MOUSE
NC score	0.101261 (rank : 476)	θ value	0.0736092 (rank : 260)
Query Neighborhood Hits	557	Target Neighborhood Hits	241	Shared Neighborhood Hits	132
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ZNFX1_MOUSE
NC score	0.100891 (rank : 477)	θ value	θ > 10 (rank : 992)
Query Neighborhood Hits	557	Target Neighborhood Hits	407	Shared Neighborhood Hits	97
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

MT1G_HUMAN
NC score	0.100773 (rank : 478)	θ value	θ > 10 (rank : 813)
Query Neighborhood Hits	557	Target Neighborhood Hits	63	Shared Neighborhood Hits	30
SwissProt Accessions	P13640, P80296	Gene names	MT1G, MT1K, MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1G (MT-1G) (Metallothionein-IG) (MT-IG) (Metallothionein-1K) (MT-1K).

ADAM2_MOUSE
NC score	0.100450 (rank : 479)	θ value	θ > 10 (rank : 577)
Query Neighborhood Hits	557	Target Neighborhood Hits	209	Shared Neighborhood Hits	121
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

RSPO2_HUMAN
NC score	0.100279 (rank : 480)	θ value	2.36792 (rank : 430)
Query Neighborhood Hits	557	Target Neighborhood Hits	90	Shared Neighborhood Hits	42
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

MT1L_HUMAN
NC score	0.100177 (rank : 481)	θ value	θ > 10 (rank : 816)
Query Neighborhood Hits	557	Target Neighborhood Hits	73	Shared Neighborhood Hits	37
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

ZNFX1_HUMAN
NC score	0.099979 (rank : 482)	θ value	θ > 10 (rank : 991)
Query Neighborhood Hits	557	Target Neighborhood Hits	308	Shared Neighborhood Hits	88
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

MEP1A_MOUSE
NC score	0.099855 (rank : 483)	θ value	θ > 10 (rank : 804)
Query Neighborhood Hits	557	Target Neighborhood Hits	166	Shared Neighborhood Hits	98
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

CSPG4_MOUSE
NC score	0.099822 (rank : 484)	θ value	θ > 10 (rank : 655)
Query Neighborhood Hits	557	Target Neighborhood Hits	105	Shared Neighborhood Hits	34
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

PGH2_HUMAN
NC score	0.099750 (rank : 485)	θ value	θ > 10 (rank : 862)
Query Neighborhood Hits	557	Target Neighborhood Hits	103	Shared Neighborhood Hits	64
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

TLL2_MOUSE
NC score	0.099017 (rank : 486)	θ value	θ > 10 (rank : 929)
Query Neighborhood Hits	557	Target Neighborhood Hits	240	Shared Neighborhood Hits	111
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TR19L_HUMAN
NC score	0.099013 (rank : 487)	θ value	θ > 10 (rank : 958)
Query Neighborhood Hits	557	Target Neighborhood Hits	99	Shared Neighborhood Hits	48
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

RSPO2_MOUSE
NC score	0.098753 (rank : 488)	θ value	4.03905 (rank : 478)
Query Neighborhood Hits	557	Target Neighborhood Hits	88	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

NACAM_MOUSE
NC score	0.098448 (rank : 489)	θ value	5.44631e-05 (rank : 130)
Query Neighborhood Hits	557	Target Neighborhood Hits	1866	Shared Neighborhood Hits	181
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

TNR6_HUMAN
NC score	0.097418 (rank : 490)	θ value	θ > 10 (rank : 948)
Query Neighborhood Hits	557	Target Neighborhood Hits	95	Shared Neighborhood Hits	58
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

FINC_HUMAN
NC score	0.097257 (rank : 491)	θ value	3.0926 (rank : 444)
Query Neighborhood Hits	557	Target Neighborhood Hits	302	Shared Neighborhood Hits	77
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

MATN1_MOUSE
NC score	0.097089 (rank : 492)	θ value	θ > 10 (rank : 798)
Query Neighborhood Hits	557	Target Neighborhood Hits	186	Shared Neighborhood Hits	82
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

FINC_MOUSE
NC score	0.096979 (rank : 493)	θ value	5.27518 (rank : 491)
Query Neighborhood Hits	557	Target Neighborhood Hits	309	Shared Neighborhood Hits	82
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

CD320_HUMAN
NC score	0.096963 (rank : 494)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	557	Target Neighborhood Hits	103	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

ADAM7_MOUSE
NC score	0.096790 (rank : 495)	θ value	0.00298849 (rank : 179)
Query Neighborhood Hits	557	Target Neighborhood Hits	200	Shared Neighborhood Hits	118
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

MATN1_HUMAN
NC score	0.096575 (rank : 496)	θ value	θ > 10 (rank : 797)
Query Neighborhood Hits	557	Target Neighborhood Hits	191	Shared Neighborhood Hits	86
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

PGH1_MOUSE
NC score	0.096180 (rank : 497)	θ value	θ > 10 (rank : 861)
Query Neighborhood Hits	557	Target Neighborhood Hits	100	Shared Neighborhood Hits	61
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

MDC1_HUMAN
NC score	0.095427 (rank : 498)	θ value	0.00020696 (rank : 149)
Query Neighborhood Hits	557	Target Neighborhood Hits	1446	Shared Neighborhood Hits	138
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

ADM1A_MOUSE
NC score	0.095345 (rank : 499)	θ value	2.36792 (rank : 419)
Query Neighborhood Hits	557	Target Neighborhood Hits	230	Shared Neighborhood Hits	138
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

NRG2_HUMAN
NC score	0.095053 (rank : 500)	θ value	θ > 10 (rank : 834)
Query Neighborhood Hits	557	Target Neighborhood Hits	419	Shared Neighborhood Hits	96
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

APR3_HUMAN
NC score	0.095027 (rank : 501)	θ value	θ > 10 (rank : 583)
Query Neighborhood Hits	557	Target Neighborhood Hits	50	Shared Neighborhood Hits	45
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

HCFC1_HUMAN
NC score	0.094815 (rank : 502)	θ value	0.0193708 (rank : 220)
Query Neighborhood Hits	557	Target Neighborhood Hits	331	Shared Neighborhood Hits	77
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

ADA25_MOUSE
NC score	0.094694 (rank : 503)	θ value	0.0736092 (rank : 259)
Query Neighborhood Hits	557	Target Neighborhood Hits	213	Shared Neighborhood Hits	128
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

ADA17_HUMAN
NC score	0.094643 (rank : 504)	θ value	θ > 10 (rank : 565)
Query Neighborhood Hits	557	Target Neighborhood Hits	223	Shared Neighborhood Hits	110
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

GSCR1_HUMAN
NC score	0.094481 (rank : 505)	θ value	θ > 10 (rank : 721)
Query Neighborhood Hits	557	Target Neighborhood Hits	674	Shared Neighborhood Hits	132
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

NRG4_MOUSE
NC score	0.093346 (rank : 506)	θ value	θ > 10 (rank : 839)
Query Neighborhood Hits	557	Target Neighborhood Hits	79	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

MEP1A_HUMAN
NC score	0.092701 (rank : 507)	θ value	θ > 10 (rank : 803)
Query Neighborhood Hits	557	Target Neighborhood Hits	162	Shared Neighborhood Hits	96
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

HCFC1_MOUSE
NC score	0.092668 (rank : 508)	θ value	0.0113563 (rank : 204)
Query Neighborhood Hits	557	Target Neighborhood Hits	348	Shared Neighborhood Hits	78
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

FST_HUMAN
NC score	0.092666 (rank : 509)	θ value	θ > 10 (rank : 696)
Query Neighborhood Hits	557	Target Neighborhood Hits	129	Shared Neighborhood Hits	55
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

SPR2H_MOUSE
NC score	0.091600 (rank : 510)	θ value	θ > 10 (rank : 910)
Query Neighborhood Hits	557	Target Neighborhood Hits	82	Shared Neighborhood Hits	40
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

FHL3_MOUSE
NC score	0.091263 (rank : 511)	θ value	0.0431538 (rank : 245)
Query Neighborhood Hits	557	Target Neighborhood Hits	424	Shared Neighborhood Hits	56
SwissProt Accessions	Q9R059, Q9JLP5, Q9WUH3	Gene names	Fhl3
Domain Architecture
Description	Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM- protein 2) (SLIM 2).

EREG_HUMAN
NC score	0.091261 (rank : 512)	θ value	θ > 10 (rank : 682)
Query Neighborhood Hits	557	Target Neighborhood Hits	73	Shared Neighborhood Hits	46
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

MUCDL_HUMAN
NC score	0.090477 (rank : 513)	θ value	0.21417 (rank : 306)
Query Neighborhood Hits	557	Target Neighborhood Hits	777	Shared Neighborhood Hits	111
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

CN032_MOUSE
NC score	0.089527 (rank : 514)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	557	Target Neighborhood Hits	233	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

TR10B_MOUSE
NC score	0.089278 (rank : 515)	θ value	θ > 10 (rank : 956)
Query Neighborhood Hits	557	Target Neighborhood Hits	76	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

CN032_HUMAN
NC score	0.088909 (rank : 516)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	557	Target Neighborhood Hits	267	Shared Neighborhood Hits	74
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

ADA24_MOUSE
NC score	0.088433 (rank : 517)	θ value	θ > 10 (rank : 571)
Query Neighborhood Hits	557	Target Neighborhood Hits	230	Shared Neighborhood Hits	131
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ADA32_HUMAN
NC score	0.087712 (rank : 518)	θ value	θ > 10 (rank : 574)
Query Neighborhood Hits	557	Target Neighborhood Hits	216	Shared Neighborhood Hits	126
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA18_HUMAN
NC score	0.086852 (rank : 519)	θ value	θ > 10 (rank : 567)
Query Neighborhood Hits	557	Target Neighborhood Hits	184	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

GGN_HUMAN
NC score	0.086441 (rank : 520)	θ value	θ > 10 (rank : 700)
Query Neighborhood Hits	557	Target Neighborhood Hits	269	Shared Neighborhood Hits	79
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

SPR2D_MOUSE
NC score	0.086310 (rank : 521)	θ value	θ > 10 (rank : 905)
Query Neighborhood Hits	557	Target Neighborhood Hits	61	Shared Neighborhood Hits	29
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

SF3A2_MOUSE
NC score	0.086275 (rank : 522)	θ value	θ > 10 (rank : 896)
Query Neighborhood Hits	557	Target Neighborhood Hits	247	Shared Neighborhood Hits	68
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

THYG_HUMAN
NC score	0.086224 (rank : 523)	θ value	0.0148317 (rank : 213)
Query Neighborhood Hits	557	Target Neighborhood Hits	154	Shared Neighborhood Hits	70
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

ADA12_HUMAN
NC score	0.086088 (rank : 524)	θ value	θ > 10 (rank : 561)
Query Neighborhood Hits	557	Target Neighborhood Hits	224	Shared Neighborhood Hits	116
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

LRP12_HUMAN
NC score	0.085482 (rank : 525)	θ value	θ > 10 (rank : 784)
Query Neighborhood Hits	557	Target Neighborhood Hits	205	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

SELPL_MOUSE
NC score	0.085335 (rank : 526)	θ value	0.00228821 (rank : 178)
Query Neighborhood Hits	557	Target Neighborhood Hits	588	Shared Neighborhood Hits	87
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

DKK3_MOUSE
NC score	0.084851 (rank : 527)	θ value	θ > 10 (rank : 663)
Query Neighborhood Hits	557	Target Neighborhood Hits	83	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

ADA12_MOUSE
NC score	0.084772 (rank : 528)	θ value	θ > 10 (rank : 562)
Query Neighborhood Hits	557	Target Neighborhood Hits	474	Shared Neighborhood Hits	135
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

MT1F_HUMAN
NC score	0.084442 (rank : 529)	θ value	θ > 10 (rank : 812)
Query Neighborhood Hits	557	Target Neighborhood Hits	73	Shared Neighborhood Hits	42
SwissProt Accessions	P04733, Q9UI97	Gene names	MT1F
Domain Architecture	No domain graphic available
Description	Metallothionein-1F (MT-1F) (Metallothionein-IF) (MT-IF).

GP112_HUMAN
NC score	0.084251 (rank : 530)	θ value	0.62314 (rank : 352)
Query Neighborhood Hits	557	Target Neighborhood Hits	441	Shared Neighborhood Hits	75
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

EPHB4_HUMAN
NC score	0.084179 (rank : 531)	θ value	0.0252991 (rank : 231)
Query Neighborhood Hits	557	Target Neighborhood Hits	1056	Shared Neighborhood Hits	156
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

TR11B_MOUSE
NC score	0.083807 (rank : 532)	θ value	θ > 10 (rank : 957)
Query Neighborhood Hits	557	Target Neighborhood Hits	95	Shared Neighborhood Hits	51
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

WASIP_HUMAN
NC score	0.083563 (rank : 533)	θ value	θ > 10 (rank : 976)
Query Neighborhood Hits	557	Target Neighborhood Hits	458	Shared Neighborhood Hits	98
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

FHL3_HUMAN
NC score	0.083428 (rank : 534)	θ value	0.0961366 (rank : 276)
Query Neighborhood Hits	557	Target Neighborhood Hits	354	Shared Neighborhood Hits	47
SwissProt Accessions	Q13643	Gene names	FHL3, SLIM2
Domain Architecture
Description	Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM- protein 2) (SLIM 2).

ADA21_MOUSE
NC score	0.083364 (rank : 535)	θ value	3.0926 (rank : 438)
Query Neighborhood Hits	557	Target Neighborhood Hits	172	Shared Neighborhood Hits	103
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

MUC1_MOUSE
NC score	0.083309 (rank : 536)	θ value	3.0926 (rank : 453)
Query Neighborhood Hits	557	Target Neighborhood Hits	388	Shared Neighborhood Hits	68
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

WASIP_MOUSE
NC score	0.083234 (rank : 537)	θ value	θ > 10 (rank : 977)
Query Neighborhood Hits	557	Target Neighborhood Hits	392	Shared Neighborhood Hits	96
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

ADA17_MOUSE
NC score	0.083025 (rank : 538)	θ value	θ > 10 (rank : 566)
Query Neighborhood Hits	557	Target Neighborhood Hits	201	Shared Neighborhood Hits	100
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

TNR1A_HUMAN
NC score	0.082729 (rank : 539)	θ value	θ > 10 (rank : 937)
Query Neighborhood Hits	557	Target Neighborhood Hits	121	Shared Neighborhood Hits	60
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

PRG4_MOUSE
NC score	0.082365 (rank : 540)	θ value	θ > 10 (rank : 870)
Query Neighborhood Hits	557	Target Neighborhood Hits	624	Shared Neighborhood Hits	115
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

TAF4_HUMAN
NC score	0.082355 (rank : 541)	θ value	θ > 10 (rank : 916)
Query Neighborhood Hits	557	Target Neighborhood Hits	687	Shared Neighborhood Hits	114
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

ST14_HUMAN
NC score	0.082127 (rank : 542)	θ value	0.0961366 (rank : 282)
Query Neighborhood Hits	557	Target Neighborhood Hits	409	Shared Neighborhood Hits	128
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

MLL2_HUMAN
NC score	0.082111 (rank : 543)	θ value	3.0926 (rank : 452)
Query Neighborhood Hits	557	Target Neighborhood Hits	1788	Shared Neighborhood Hits	189
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

ADA30_HUMAN
NC score	0.081951 (rank : 544)	θ value	θ > 10 (rank : 573)
Query Neighborhood Hits	557	Target Neighborhood Hits	391	Shared Neighborhood Hits	115
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ADA32_MOUSE
NC score	0.081754 (rank : 545)	θ value	θ > 10 (rank : 575)
Query Neighborhood Hits	557	Target Neighborhood Hits	219	Shared Neighborhood Hits	124
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

LRP12_MOUSE
NC score	0.081687 (rank : 546)	θ value	θ > 10 (rank : 785)
Query Neighborhood Hits	557	Target Neighborhood Hits	180	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

CK024_MOUSE
NC score	0.081278 (rank : 547)	θ value	0.0148317 (rank : 208)
Query Neighborhood Hits	557	Target Neighborhood Hits	307	Shared Neighborhood Hits	63
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

TR11B_HUMAN
NC score	0.081173 (rank : 548)	θ value	4.03905 (rank : 485)
Query Neighborhood Hits	557	Target Neighborhood Hits	92	Shared Neighborhood Hits	51
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

PRP1_HUMAN
NC score	0.081085 (rank : 549)	θ value	θ > 10 (rank : 872)
Query Neighborhood Hits	557	Target Neighborhood Hits	385	Shared Neighborhood Hits	79
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

ST14_MOUSE
NC score	0.080893 (rank : 550)	θ value	0.47712 (rank : 347)
Query Neighborhood Hits	557	Target Neighborhood Hits	419	Shared Neighborhood Hits	138
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

MDC1_MOUSE
NC score	0.080870 (rank : 551)	θ value	0.0563607 (rank : 251)
Query Neighborhood Hits	557	Target Neighborhood Hits	998	Shared Neighborhood Hits	122
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

LCE3B_HUMAN
NC score	0.080718 (rank : 552)	θ value	θ > 10 (rank : 770)
Query Neighborhood Hits	557	Target Neighborhood Hits	47	Shared Neighborhood Hits	29
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

MUCDL_MOUSE
NC score	0.080677 (rank : 553)	θ value	θ > 10 (rank : 828)
Query Neighborhood Hits	557	Target Neighborhood Hits	461	Shared Neighborhood Hits	85
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

ADM1B_MOUSE
NC score	0.079990 (rank : 554)	θ value	θ > 10 (rank : 581)
Query Neighborhood Hits	557	Target Neighborhood Hits	236	Shared Neighborhood Hits	112
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

CO8A_HUMAN
NC score	0.079967 (rank : 555)	θ value	6.88961 (rank : 512)
Query Neighborhood Hits	557	Target Neighborhood Hits	200	Shared Neighborhood Hits	83
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

DKK3_HUMAN
NC score	0.079903 (rank : 556)	θ value	θ > 10 (rank : 662)
Query Neighborhood Hits	557	Target Neighborhood Hits	74	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UBP4, Q9ULB7	Gene names	DKK3, REIC
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3).

SF3A2_HUMAN
NC score	0.079850 (rank : 557)	θ value	θ > 10 (rank : 895)
Query Neighborhood Hits	557	Target Neighborhood Hits	263	Shared Neighborhood Hits	65
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

KR111_HUMAN
NC score	0.079806 (rank : 558)	θ value	θ > 10 (rank : 734)
Query Neighborhood Hits	557	Target Neighborhood Hits	90	Shared Neighborhood Hits	52
SwissProt Accessions	Q8IUC1	Gene names	KRTAP11-1, KAP11.1, KRTAP11.1
Domain Architecture
Description	Keratin-associated protein 11-1 (High sulfur keratin-associated protein 11.1).

PGH1_HUMAN
NC score	0.079450 (rank : 559)	θ value	θ > 10 (rank : 860)
Query Neighborhood Hits	557	Target Neighborhood Hits	91	Shared Neighborhood Hits	54
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

TPA_MOUSE
NC score	0.079266 (rank : 560)	θ value	θ > 10 (rank : 953)
Query Neighborhood Hits	557	Target Neighborhood Hits	335	Shared Neighborhood Hits	126
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

PRB3_HUMAN
NC score	0.079064 (rank : 561)	θ value	θ > 10 (rank : 868)
Query Neighborhood Hits	557	Target Neighborhood Hits	318	Shared Neighborhood Hits	65
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

MT2_HUMAN
NC score	0.078739 (rank : 562)	θ value	θ > 10 (rank : 820)
Query Neighborhood Hits	557	Target Neighborhood Hits	69	Shared Neighborhood Hits	41
SwissProt Accessions	P02795, Q14823, Q2HXR9, Q53XT9	Gene names	MT2A, CES1, MT2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II) (Metallothionein-2A).

TM108_MOUSE
NC score	0.078553 (rank : 563)	θ value	0.0431538 (rank : 248)
Query Neighborhood Hits	557	Target Neighborhood Hits	336	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

PARM1_MOUSE
NC score	0.078363 (rank : 564)	θ value	0.0431538 (rank : 247)
Query Neighborhood Hits	557	Target Neighborhood Hits	140	Shared Neighborhood Hits	39
SwissProt Accessions	Q923D3, Q3TTV0, Q3UFU4	Gene names
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

GGN_MOUSE
NC score	0.078354 (rank : 565)	θ value	θ > 10 (rank : 701)
Query Neighborhood Hits	557	Target Neighborhood Hits	311	Shared Neighborhood Hits	89
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

MLL3_HUMAN
NC score	0.078114 (rank : 566)	θ value	0.125558 (rank : 292)
Query Neighborhood Hits	557	Target Neighborhood Hits	1644	Shared Neighborhood Hits	179
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

FNDC3_MOUSE
NC score	0.077996 (rank : 567)	θ value	θ > 10 (rank : 693)
Query Neighborhood Hits	557	Target Neighborhood Hits	207	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

MLL3_MOUSE
NC score	0.077962 (rank : 568)	θ value	0.365318 (rank : 327)
Query Neighborhood Hits	557	Target Neighborhood Hits	1399	Shared Neighborhood Hits	170
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

SPR2G_MOUSE
NC score	0.077604 (rank : 569)	θ value	θ > 10 (rank : 909)
Query Neighborhood Hits	557	Target Neighborhood Hits	53	Shared Neighborhood Hits	27
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

KR131_HUMAN
NC score	0.077484 (rank : 570)	θ value	θ > 10 (rank : 738)
Query Neighborhood Hits	557	Target Neighborhood Hits	123	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IUC0, Q3LI79	Gene names	KRTAP13-1, KAP13.1, KRTAP13.1
Domain Architecture
Description	Keratin-associated protein 13-1 (High sulfur keratin-associated protein 13.1).

ASTN_MOUSE
NC score	0.077314 (rank : 571)	θ value	θ > 10 (rank : 586)
Query Neighborhood Hits	557	Target Neighborhood Hits	98	Shared Neighborhood Hits	56
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

BSN_HUMAN
NC score	0.077056 (rank : 572)	θ value	0.00665767 (rank : 192)
Query Neighborhood Hits	557	Target Neighborhood Hits	1537	Shared Neighborhood Hits	152
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

BSN_MOUSE
NC score	0.076995 (rank : 573)	θ value	0.0330416 (rank : 239)
Query Neighborhood Hits	557	Target Neighborhood Hits	2057	Shared Neighborhood Hits	162
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

ADAM2_HUMAN
NC score	0.076819 (rank : 574)	θ value	θ > 10 (rank : 576)
Query Neighborhood Hits	557	Target Neighborhood Hits	175	Shared Neighborhood Hits	100
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

BAI1_HUMAN
NC score	0.076705 (rank : 575)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	557	Target Neighborhood Hits	375	Shared Neighborhood Hits	97
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

ADA21_HUMAN
NC score	0.076673 (rank : 576)	θ value	θ > 10 (rank : 570)
Query Neighborhood Hits	557	Target Neighborhood Hits	181	Shared Neighborhood Hits	108
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

RSPO1_HUMAN
NC score	0.076531 (rank : 577)	θ value	θ > 10 (rank : 882)
Query Neighborhood Hits	557	Target Neighborhood Hits	101	Shared Neighborhood Hits	49
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

THYG_MOUSE
NC score	0.076525 (rank : 578)	θ value	0.0193708 (rank : 223)
Query Neighborhood Hits	557	Target Neighborhood Hits	161	Shared Neighborhood Hits	72
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

ASTN_HUMAN
NC score	0.076248 (rank : 579)	θ value	θ > 10 (rank : 585)
Query Neighborhood Hits	557	Target Neighborhood Hits	105	Shared Neighborhood Hits	56
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

MUC1_HUMAN
NC score	0.076093 (rank : 580)	θ value	5.26297e-08 (rank : 87)
Query Neighborhood Hits	557	Target Neighborhood Hits	975	Shared Neighborhood Hits	106
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MBD6_HUMAN
NC score	0.075977 (rank : 581)	θ value	θ > 10 (rank : 800)
Query Neighborhood Hits	557	Target Neighborhood Hits	349	Shared Neighborhood Hits	89
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

ATN1_HUMAN
NC score	0.075910 (rank : 582)	θ value	θ > 10 (rank : 587)
Query Neighborhood Hits	557	Target Neighborhood Hits	676	Shared Neighborhood Hits	107
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

ADA29_HUMAN
NC score	0.075694 (rank : 583)	θ value	θ > 10 (rank : 572)
Query Neighborhood Hits	557	Target Neighborhood Hits	247	Shared Neighborhood Hits	116
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

TPA_HUMAN
NC score	0.075396 (rank : 584)	θ value	θ > 10 (rank : 952)
Query Neighborhood Hits	557	Target Neighborhood Hits	324	Shared Neighborhood Hits	123
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

CYR61_MOUSE
NC score	0.075262 (rank : 585)	θ value	θ > 10 (rank : 659)
Query Neighborhood Hits	557	Target Neighborhood Hits	156	Shared Neighborhood Hits	62
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

FNDC3_HUMAN
NC score	0.075092 (rank : 586)	θ value	θ > 10 (rank : 692)
Query Neighborhood Hits	557	Target Neighborhood Hits	196	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

TNR1B_MOUSE
NC score	0.075061 (rank : 587)	θ value	θ > 10 (rank : 938)
Query Neighborhood Hits	557	Target Neighborhood Hits	123	Shared Neighborhood Hits	59
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

CO9_HUMAN
NC score	0.074923 (rank : 588)	θ value	θ > 10 (rank : 636)
Query Neighborhood Hits	557	Target Neighborhood Hits	147	Shared Neighborhood Hits	64
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

GP128_MOUSE
NC score	0.074850 (rank : 589)	θ value	θ > 10 (rank : 712)
Query Neighborhood Hits	557	Target Neighborhood Hits	141	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BM96, Q80T42	Gene names	Gpr128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

NCOA6_MOUSE
NC score	0.074537 (rank : 590)	θ value	0.00665767 (rank : 195)
Query Neighborhood Hits	557	Target Neighborhood Hits	1076	Shared Neighborhood Hits	130
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

KR123_HUMAN
NC score	0.074462 (rank : 591)	θ value	θ > 10 (rank : 736)
Query Neighborhood Hits	557	Target Neighborhood Hits	75	Shared Neighborhood Hits	35
SwissProt Accessions	P60328	Gene names	KRTAP12-3, KAP12.3, KRTAP12.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-3 (Keratin-associated protein 12.3) (High sulfur keratin-associated protein 12.3).

CO9_MOUSE
NC score	0.074375 (rank : 592)	θ value	θ > 10 (rank : 637)
Query Neighborhood Hits	557	Target Neighborhood Hits	153	Shared Neighborhood Hits	68
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

RAPH1_HUMAN
NC score	0.074321 (rank : 593)	θ value	θ > 10 (rank : 876)
Query Neighborhood Hits	557	Target Neighborhood Hits	593	Shared Neighborhood Hits	120
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

PAPPA_MOUSE
NC score	0.074176 (rank : 594)	θ value	θ > 10 (rank : 849)
Query Neighborhood Hits	557	Target Neighborhood Hits	153	Shared Neighborhood Hits	67
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PAPPA_HUMAN
NC score	0.073513 (rank : 595)	θ value	θ > 10 (rank : 848)
Query Neighborhood Hits	557	Target Neighborhood Hits	161	Shared Neighborhood Hits	69
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

TR10C_HUMAN
NC score	0.073410 (rank : 596)	θ value	5.27518 (rank : 501)
Query Neighborhood Hits	557	Target Neighborhood Hits	105	Shared Neighborhood Hits	59
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

PO121_HUMAN
NC score	0.073319 (rank : 597)	θ value	θ > 10 (rank : 866)
Query Neighborhood Hits	557	Target Neighborhood Hits	344	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

CYR61_HUMAN
NC score	0.072798 (rank : 598)	θ value	θ > 10 (rank : 658)
Query Neighborhood Hits	557	Target Neighborhood Hits	159	Shared Neighborhood Hits	63
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

EPHB6_HUMAN
NC score	0.072688 (rank : 599)	θ value	0.125558 (rank : 286)
Query Neighborhood Hits	557	Target Neighborhood Hits	912	Shared Neighborhood Hits	116
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

MAGE1_HUMAN
NC score	0.072176 (rank : 600)	θ value	0.000158464 (rank : 144)
Query Neighborhood Hits	557	Target Neighborhood Hits	1389	Shared Neighborhood Hits	141
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

NFRKB_HUMAN
NC score	0.072053 (rank : 601)	θ value	0.0736092 (rank : 267)
Query Neighborhood Hits	557	Target Neighborhood Hits	211	Shared Neighborhood Hits	52
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

MT1I_HUMAN
NC score	0.071824 (rank : 602)	θ value	θ > 10 (rank : 815)
Query Neighborhood Hits	557	Target Neighborhood Hits	64	Shared Neighborhood Hits	36
SwissProt Accessions	P80295	Gene names	MT1I
Domain Architecture	No domain graphic available
Description	Metallothionein-1I (MT-1I) (Metallothionein-II).

SPR2F_HUMAN
NC score	0.071786 (rank : 603)	θ value	θ > 10 (rank : 908)
Query Neighborhood Hits	557	Target Neighborhood Hits	33	Shared Neighborhood Hits	16
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

SON_MOUSE
NC score	0.071769 (rank : 604)	θ value	1.81305 (rank : 410)
Query Neighborhood Hits	557	Target Neighborhood Hits	957	Shared Neighborhood Hits	111
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

CO8B_HUMAN
NC score	0.071653 (rank : 605)	θ value	θ > 10 (rank : 634)
Query Neighborhood Hits	557	Target Neighborhood Hits	199	Shared Neighborhood Hits	70
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

WIRE_HUMAN
NC score	0.071509 (rank : 606)	θ value	θ > 10 (rank : 985)
Query Neighborhood Hits	557	Target Neighborhood Hits	329	Shared Neighborhood Hits	82
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

SRRM1_MOUSE
NC score	0.071383 (rank : 607)	θ value	θ > 10 (rank : 913)
Query Neighborhood Hits	557	Target Neighborhood Hits	966	Shared Neighborhood Hits	114
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

EPHA7_HUMAN
NC score	0.071060 (rank : 608)	θ value	0.0113563 (rank : 203)
Query Neighborhood Hits	557	Target Neighborhood Hits	1053	Shared Neighborhood Hits	135
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

PRB4S_HUMAN
NC score	0.070929 (rank : 609)	θ value	θ > 10 (rank : 869)
Query Neighborhood Hits	557	Target Neighborhood Hits	330	Shared Neighborhood Hits	65
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

MUC24_HUMAN
NC score	0.070810 (rank : 610)	θ value	0.0961366 (rank : 280)
Query Neighborhood Hits	557	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q04900, Q5JSU6	Gene names	CD164
Domain Architecture
Description	Putative mucin core protein 24 precursor (Multi-glycosylated core protein 24) (MGC-24) (MUC-24) (CD164 antigen).

MADCA_HUMAN
NC score	0.070645 (rank : 611)	θ value	θ > 10 (rank : 795)
Query Neighborhood Hits	557	Target Neighborhood Hits	221	Shared Neighborhood Hits	64
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

SRCH_HUMAN
NC score	0.070592 (rank : 612)	θ value	1.38821 (rank : 391)
Query Neighborhood Hits	557	Target Neighborhood Hits	225	Shared Neighborhood Hits	37
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

BAI1_MOUSE
NC score	0.070486 (rank : 613)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	557	Target Neighborhood Hits	340	Shared Neighborhood Hits	78
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

COCA1_MOUSE
NC score	0.070094 (rank : 614)	θ value	θ > 10 (rank : 639)
Query Neighborhood Hits	557	Target Neighborhood Hits	467	Shared Neighborhood Hits	83
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

GP128_HUMAN
NC score	0.070016 (rank : 615)	θ value	θ > 10 (rank : 711)
Query Neighborhood Hits	557	Target Neighborhood Hits	135	Shared Neighborhood Hits	40
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

TNR21_MOUSE
NC score	0.069916 (rank : 616)	θ value	θ > 10 (rank : 940)
Query Neighborhood Hits	557	Target Neighborhood Hits	108	Shared Neighborhood Hits	56
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

CJ078_MOUSE
NC score	0.069797 (rank : 617)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	557	Target Neighborhood Hits	559	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

KR133_HUMAN
NC score	0.069763 (rank : 618)	θ value	0.813845 (rank : 362)
Query Neighborhood Hits	557	Target Neighborhood Hits	66	Shared Neighborhood Hits	37
SwissProt Accessions	Q3SY46, Q3LI78	Gene names	KRTAP13-3, KAP13.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-3.

BASP_MOUSE
NC score	0.069532 (rank : 619)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	557	Target Neighborhood Hits	260	Shared Neighborhood Hits	51
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

SON_HUMAN
NC score	0.069258 (rank : 620)	θ value	0.000602161 (rank : 157)
Query Neighborhood Hits	557	Target Neighborhood Hits	1568	Shared Neighborhood Hits	137
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

NRG3_MOUSE
NC score	0.068573 (rank : 621)	θ value	θ > 10 (rank : 837)
Query Neighborhood Hits	557	Target Neighborhood Hits	132	Shared Neighborhood Hits	70
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

WIRE_MOUSE
NC score	0.068525 (rank : 622)	θ value	θ > 10 (rank : 986)
Query Neighborhood Hits	557	Target Neighborhood Hits	310	Shared Neighborhood Hits	78
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

EPHAA_HUMAN
NC score	0.068267 (rank : 623)	θ value	0.0252991 (rank : 230)
Query Neighborhood Hits	557	Target Neighborhood Hits	960	Shared Neighborhood Hits	93
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

NRX3B_HUMAN
NC score	0.068075 (rank : 624)	θ value	θ > 10 (rank : 844)
Query Neighborhood Hits	557	Target Neighborhood Hits	36	Shared Neighborhood Hits	18
SwissProt Accessions	Q9HDB5	Gene names	NRXN3, KIAA0743
Domain Architecture	No domain graphic available
Description	Neurexin-3-beta precursor (Neurexin III-beta).

SRRM1_HUMAN
NC score	0.067946 (rank : 625)	θ value	θ > 10 (rank : 912)
Query Neighborhood Hits	557	Target Neighborhood Hits	690	Shared Neighborhood Hits	94
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

MEP1B_MOUSE
NC score	0.067788 (rank : 626)	θ value	θ > 10 (rank : 805)
Query Neighborhood Hits	557	Target Neighborhood Hits	127	Shared Neighborhood Hits	66
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

TNR18_HUMAN
NC score	0.067659 (rank : 627)	θ value	θ > 10 (rank : 934)
Query Neighborhood Hits	557	Target Neighborhood Hits	55	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

NFRKB_MOUSE
NC score	0.067443 (rank : 628)	θ value	0.0563607 (rank : 252)
Query Neighborhood Hits	557	Target Neighborhood Hits	393	Shared Neighborhood Hits	73
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

RERE_MOUSE
NC score	0.067296 (rank : 629)	θ value	4.03905 (rank : 476)
Query Neighborhood Hits	557	Target Neighborhood Hits	785	Shared Neighborhood Hits	123
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

NELFA_HUMAN
NC score	0.067007 (rank : 630)	θ value	1.81305 (rank : 406)
Query Neighborhood Hits	557	Target Neighborhood Hits	161	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H3P2, O95392	Gene names	WHSC2, NELFA
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein).

YLPM1_MOUSE
NC score	0.066961 (rank : 631)	θ value	θ > 10 (rank : 987)
Query Neighborhood Hits	557	Target Neighborhood Hits	505	Shared Neighborhood Hits	95
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

COCA1_HUMAN
NC score	0.066865 (rank : 632)	θ value	θ > 10 (rank : 638)
Query Neighborhood Hits	557	Target Neighborhood Hits	458	Shared Neighborhood Hits	74
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

ZN207_HUMAN
NC score	0.066857 (rank : 633)	θ value	θ > 10 (rank : 989)
Query Neighborhood Hits	557	Target Neighborhood Hits	326	Shared Neighborhood Hits	65
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

MT1M_HUMAN
NC score	0.066804 (rank : 634)	θ value	θ > 10 (rank : 817)
Query Neighborhood Hits	557	Target Neighborhood Hits	72	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N339, Q8TDN3	Gene names	MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1M (MT-1M) (Metallothionein-IM) (MT-IM).

NU214_HUMAN
NC score	0.066559 (rank : 635)	θ value	θ > 10 (rank : 845)
Query Neighborhood Hits	557	Target Neighborhood Hits	657	Shared Neighborhood Hits	96
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

TM108_HUMAN
NC score	0.066468 (rank : 636)	θ value	3.0926 (rank : 459)
Query Neighborhood Hits	557	Target Neighborhood Hits	166	Shared Neighborhood Hits	55
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

EPHB4_MOUSE
NC score	0.066432 (rank : 637)	θ value	θ > 10 (rank : 681)
Query Neighborhood Hits	557	Target Neighborhood Hits	1013	Shared Neighborhood Hits	130
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

WASL_HUMAN
NC score	0.066352 (rank : 638)	θ value	θ > 10 (rank : 978)
Query Neighborhood Hits	557	Target Neighborhood Hits	312	Shared Neighborhood Hits	82
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASL_MOUSE
NC score	0.066266 (rank : 639)	θ value	θ > 10 (rank : 979)
Query Neighborhood Hits	557	Target Neighborhood Hits	339	Shared Neighborhood Hits	83
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

SMR1_MOUSE
NC score	0.065978 (rank : 640)	θ value	θ > 10 (rank : 902)
Query Neighborhood Hits	557	Target Neighborhood Hits	103	Shared Neighborhood Hits	42
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

KR134_HUMAN
NC score	0.065832 (rank : 641)	θ value	θ > 10 (rank : 740)
Query Neighborhood Hits	557	Target Neighborhood Hits	81	Shared Neighborhood Hits	36
SwissProt Accessions	Q3LI77	Gene names	KRTAP13-4, KAP13.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-4.

EPGN_MOUSE
NC score	0.065807 (rank : 642)	θ value	θ > 10 (rank : 678)
Query Neighborhood Hits	557	Target Neighborhood Hits	63	Shared Neighborhood Hits	38
SwissProt Accessions	Q924X1, Q8CEX5	Gene names	Epgn
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

AD26A_MOUSE
NC score	0.065438 (rank : 643)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	557	Target Neighborhood Hits	165	Shared Neighborhood Hits	96
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

SELPL_HUMAN
NC score	0.065391 (rank : 644)	θ value	θ > 10 (rank : 892)
Query Neighborhood Hits	557	Target Neighborhood Hits	68	Shared Neighborhood Hits	34
SwissProt Accessions	Q14242, Q12775	Gene names	SELPLG
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand) (CD162 antigen).

CDN1C_HUMAN
NC score	0.065302 (rank : 645)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	557	Target Neighborhood Hits	168	Shared Neighborhood Hits	54
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

BTC_MOUSE
NC score	0.065173 (rank : 646)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	557	Target Neighborhood Hits	67	Shared Neighborhood Hits	41
SwissProt Accessions	Q05928	Gene names	Btc, Bcn
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

EPHA3_MOUSE
NC score	0.065070 (rank : 647)	θ value	0.0193708 (rank : 218)
Query Neighborhood Hits	557	Target Neighborhood Hits	1009	Shared Neighborhood Hits	104
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

RERE_HUMAN
NC score	0.064825 (rank : 648)	θ value	θ > 10 (rank : 881)
Query Neighborhood Hits	557	Target Neighborhood Hits	779	Shared Neighborhood Hits	127
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

GPR98_HUMAN
NC score	0.064786 (rank : 649)	θ value	θ > 10 (rank : 718)
Query Neighborhood Hits	557	Target Neighborhood Hits	202	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

SPR2B_MOUSE
NC score	0.064592 (rank : 650)	θ value	θ > 10 (rank : 903)
Query Neighborhood Hits	557	Target Neighborhood Hits	51	Shared Neighborhood Hits	25
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

EPHB6_MOUSE
NC score	0.064258 (rank : 651)	θ value	0.0431538 (rank : 244)
Query Neighborhood Hits	557	Target Neighborhood Hits	906	Shared Neighborhood Hits	99
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

ERBB3_HUMAN
NC score	0.064104 (rank : 652)	θ value	0.0736092 (rank : 263)
Query Neighborhood Hits	557	Target Neighborhood Hits	918	Shared Neighborhood Hits	109
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

PCLO_HUMAN
NC score	0.063844 (rank : 653)	θ value	0.279714 (rank : 317)
Query Neighborhood Hits	557	Target Neighborhood Hits	2046	Shared Neighborhood Hits	166
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

EPHA1_HUMAN
NC score	0.063717 (rank : 654)	θ value	1.06291 (rank : 368)
Query Neighborhood Hits	557	Target Neighborhood Hits	997	Shared Neighborhood Hits	130
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

NRX1B_HUMAN
NC score	0.063550 (rank : 655)	θ value	θ > 10 (rank : 842)
Query Neighborhood Hits	557	Target Neighborhood Hits	37	Shared Neighborhood Hits	18
SwissProt Accessions	P58400	Gene names	NRXN1
Domain Architecture	No domain graphic available
Description	Neurexin-1-beta precursor (Neurexin I-beta).

SPRR3_MOUSE
NC score	0.063531 (rank : 656)	θ value	0.0736092 (rank : 270)
Query Neighborhood Hits	557	Target Neighborhood Hits	106	Shared Neighborhood Hits	35
SwissProt Accessions	O09116	Gene names	Sprr3
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta).

GP144_HUMAN
NC score	0.063445 (rank : 657)	θ value	θ > 10 (rank : 714)
Query Neighborhood Hits	557	Target Neighborhood Hits	108	Shared Neighborhood Hits	13
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

SELV_HUMAN
NC score	0.063356 (rank : 658)	θ value	θ > 10 (rank : 893)
Query Neighborhood Hits	557	Target Neighborhood Hits	118	Shared Neighborhood Hits	46
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

ENAH_MOUSE
NC score	0.063290 (rank : 659)	θ value	θ > 10 (rank : 675)
Query Neighborhood Hits	557	Target Neighborhood Hits	919	Shared Neighborhood Hits	122
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

FHL5_MOUSE
NC score	0.063235 (rank : 660)	θ value	0.00102713 (rank : 161)
Query Neighborhood Hits	557	Target Neighborhood Hits	463	Shared Neighborhood Hits	40
SwissProt Accessions	Q9WTX7	Gene names	Fhl5, Act
Domain Architecture	No domain graphic available
Description	Four and a half LIM domains protein 5 (FHL-5) (Activator of cAMP- responsive element modulator in testis) (Activator of CREM in testis).

TNR27_MOUSE
NC score	0.063180 (rank : 661)	θ value	θ > 10 (rank : 943)
Query Neighborhood Hits	557	Target Neighborhood Hits	61	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BX35, Q8BM50	Gene names	Eda2r, Tnfrsf27, Xedar
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

NRG3_HUMAN
NC score	0.063100 (rank : 662)	θ value	θ > 10 (rank : 836)
Query Neighborhood Hits	557	Target Neighborhood Hits	119	Shared Neighborhood Hits	60
SwissProt Accessions	P56975	Gene names	NRG3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

CO8A_MOUSE
NC score	0.063003 (rank : 663)	θ value	θ > 10 (rank : 633)
Query Neighborhood Hits	557	Target Neighborhood Hits	182	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

BTC_HUMAN
NC score	0.062973 (rank : 664)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	557	Target Neighborhood Hits	70	Shared Neighborhood Hits	40
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

CJ095_HUMAN
NC score	0.062870 (rank : 665)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	557	Target Neighborhood Hits	50	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H7T3	Gene names	C10orf95
Domain Architecture	No domain graphic available
Description	Protein C10orf95.

EPHA3_HUMAN
NC score	0.062810 (rank : 666)	θ value	0.0252991 (rank : 229)
Query Neighborhood Hits	557	Target Neighborhood Hits	1005	Shared Neighborhood Hits	106
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

CO7A1_HUMAN
NC score	0.062782 (rank : 667)	θ value	θ > 10 (rank : 631)
Query Neighborhood Hits	557	Target Neighborhood Hits	807	Shared Neighborhood Hits	112
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

EPHA2_MOUSE
NC score	0.062754 (rank : 668)	θ value	0.0736092 (rank : 262)
Query Neighborhood Hits	557	Target Neighborhood Hits	1020	Shared Neighborhood Hits	115
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

NELFA_MOUSE
NC score	0.062752 (rank : 669)	θ value	θ > 10 (rank : 829)
Query Neighborhood Hits	557	Target Neighborhood Hits	195	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

TNR21_HUMAN
NC score	0.062739 (rank : 670)	θ value	θ > 10 (rank : 939)
Query Neighborhood Hits	557	Target Neighborhood Hits	90	Shared Neighborhood Hits	51
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TR10A_HUMAN
NC score	0.062737 (rank : 671)	θ value	θ > 10 (rank : 954)
Query Neighborhood Hits	557	Target Neighborhood Hits	82	Shared Neighborhood Hits	48
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

PRRT3_HUMAN
NC score	0.062533 (rank : 672)	θ value	0.000121331 (rank : 140)
Query Neighborhood Hits	557	Target Neighborhood Hits	998	Shared Neighborhood Hits	88
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

WBP11_HUMAN
NC score	0.062409 (rank : 673)	θ value	θ > 10 (rank : 981)
Query Neighborhood Hits	557	Target Neighborhood Hits	354	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

CS016_HUMAN
NC score	0.062241 (rank : 674)	θ value	θ > 10 (rank : 651)
Query Neighborhood Hits	557	Target Neighborhood Hits	310	Shared Neighborhood Hits	80
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

BAI3_MOUSE
NC score	0.062019 (rank : 675)	θ value	θ > 10 (rank : 593)
Query Neighborhood Hits	557	Target Neighborhood Hits	250	Shared Neighborhood Hits	46
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

FHL5_HUMAN
NC score	0.061756 (rank : 676)	θ value	0.00228821 (rank : 174)
Query Neighborhood Hits	557	Target Neighborhood Hits	523	Shared Neighborhood Hits	51
SwissProt Accessions	Q5TD97, Q5TD98, Q8WW21, Q9NQU2	Gene names	FHL5, ACT
Domain Architecture	No domain graphic available
Description	Four and a half LIM domains protein 5 (FHL-5) (Activator of cAMP- responsive element modulator in testis) (Activator of CREM in testis).

PRR13_HUMAN
NC score	0.061692 (rank : 677)	θ value	θ > 10 (rank : 875)
Query Neighborhood Hits	557	Target Neighborhood Hits	105	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

EPHA2_HUMAN
NC score	0.061575 (rank : 678)	θ value	0.0193708 (rank : 217)
Query Neighborhood Hits	557	Target Neighborhood Hits	1021	Shared Neighborhood Hits	103
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

COEA1_MOUSE
NC score	0.061553 (rank : 679)	θ value	θ > 10 (rank : 641)
Query Neighborhood Hits	557	Target Neighborhood Hits	402	Shared Neighborhood Hits	57
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

INSRR_MOUSE
NC score	0.061343 (rank : 680)	θ value	θ > 10 (rank : 732)
Query Neighborhood Hits	557	Target Neighborhood Hits	961	Shared Neighborhood Hits	138
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

CIC_MOUSE
NC score	0.061318 (rank : 681)	θ value	6.88961 (rank : 511)
Query Neighborhood Hits	557	Target Neighborhood Hits	742	Shared Neighborhood Hits	128
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

WBP11_MOUSE
NC score	0.061052 (rank : 682)	θ value	θ > 10 (rank : 982)
Query Neighborhood Hits	557	Target Neighborhood Hits	362	Shared Neighborhood Hits	73
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

WASF2_MOUSE
NC score	0.061018 (rank : 683)	θ value	θ > 10 (rank : 974)
Query Neighborhood Hits	557	Target Neighborhood Hits	315	Shared Neighborhood Hits	92
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

INSRR_HUMAN
NC score	0.060704 (rank : 684)	θ value	θ > 10 (rank : 731)
Query Neighborhood Hits	557	Target Neighborhood Hits	950	Shared Neighborhood Hits	132
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

BAT2_HUMAN
NC score	0.060623 (rank : 685)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	557	Target Neighborhood Hits	931	Shared Neighborhood Hits	116
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

PI5PA_HUMAN
NC score	0.060289 (rank : 686)	θ value	0.0563607 (rank : 256)
Query Neighborhood Hits	557	Target Neighborhood Hits	749	Shared Neighborhood Hits	108
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

BAI3_HUMAN
NC score	0.060223 (rank : 687)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	557	Target Neighborhood Hits	246	Shared Neighborhood Hits	43
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

CRDL2_MOUSE
NC score	0.059990 (rank : 688)	θ value	θ > 10 (rank : 650)
Query Neighborhood Hits	557	Target Neighborhood Hits	81	Shared Neighborhood Hits	35
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

WASF4_HUMAN
NC score	0.059968 (rank : 689)	θ value	θ > 10 (rank : 975)
Query Neighborhood Hits	557	Target Neighborhood Hits	282	Shared Neighborhood Hits	83
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

GPR64_MOUSE
NC score	0.059935 (rank : 690)	θ value	θ > 10 (rank : 717)
Query Neighborhood Hits	557	Target Neighborhood Hits	156	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

KR132_HUMAN
NC score	0.059916 (rank : 691)	θ value	θ > 10 (rank : 739)
Query Neighborhood Hits	557	Target Neighborhood Hits	69	Shared Neighborhood Hits	36
SwissProt Accessions	Q52LG2	Gene names	KRTAP13-2, KAP13.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-2.

ERBB4_HUMAN
NC score	0.059772 (rank : 692)	θ value	0.125558 (rank : 287)
Query Neighborhood Hits	557	Target Neighborhood Hits	910	Shared Neighborhood Hits	98
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

COEA1_HUMAN
NC score	0.059722 (rank : 693)	θ value	θ > 10 (rank : 640)
Query Neighborhood Hits	557	Target Neighborhood Hits	427	Shared Neighborhood Hits	69
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

MLL4_HUMAN
NC score	0.059543 (rank : 694)	θ value	θ > 10 (rank : 807)
Query Neighborhood Hits	557	Target Neighborhood Hits	722	Shared Neighborhood Hits	121
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

EPHA1_MOUSE
NC score	0.059412 (rank : 695)	θ value	0.163984 (rank : 295)
Query Neighborhood Hits	557	Target Neighborhood Hits	958	Shared Neighborhood Hits	112
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

TSG6_MOUSE
NC score	0.059137 (rank : 696)	θ value	θ > 10 (rank : 961)
Query Neighborhood Hits	557	Target Neighborhood Hits	91	Shared Neighborhood Hits	17
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

GP133_HUMAN
NC score	0.059126 (rank : 697)	θ value	θ > 10 (rank : 713)
Query Neighborhood Hits	557	Target Neighborhood Hits	115	Shared Neighborhood Hits	10
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

FHL2_MOUSE
NC score	0.059118 (rank : 698)	θ value	0.21417 (rank : 303)
Query Neighborhood Hits	557	Target Neighborhood Hits	539	Shared Neighborhood Hits	56
SwissProt Accessions	O70433, P97448	Gene names	Fhl2
Domain Architecture
Description	Four and a half LIM domains protein 2 (FHL-2) (Skeletal muscle LIM- protein 3) (SLIM 3).

GPR98_MOUSE
NC score	0.059071 (rank : 699)	θ value	θ > 10 (rank : 719)
Query Neighborhood Hits	557	Target Neighborhood Hits	206	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

TSG6_HUMAN
NC score	0.058954 (rank : 700)	θ value	θ > 10 (rank : 960)
Query Neighborhood Hits	557	Target Neighborhood Hits	91	Shared Neighborhood Hits	18
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

SDK2_MOUSE
NC score	0.058832 (rank : 701)	θ value	θ > 10 (rank : 891)
Query Neighborhood Hits	557	Target Neighborhood Hits	480	Shared Neighborhood Hits	56
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

GPR64_HUMAN
NC score	0.058788 (rank : 702)	θ value	θ > 10 (rank : 716)
Query Neighborhood Hits	557	Target Neighborhood Hits	207	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

WASF2_HUMAN
NC score	0.058748 (rank : 703)	θ value	θ > 10 (rank : 973)
Query Neighborhood Hits	557	Target Neighborhood Hits	280	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

NCOA6_HUMAN
NC score	0.058724 (rank : 704)	θ value	1.06291 (rank : 376)
Query Neighborhood Hits	557	Target Neighborhood Hits	1202	Shared Neighborhood Hits	126
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

WASF1_MOUSE
NC score	0.058719 (rank : 705)	θ value	θ > 10 (rank : 972)
Query Neighborhood Hits	557	Target Neighborhood Hits	261	Shared Neighborhood Hits	83
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

BAI2_MOUSE
NC score	0.058701 (rank : 706)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	557	Target Neighborhood Hits	323	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

OGFR_HUMAN
NC score	0.058539 (rank : 707)	θ value	0.000121331 (rank : 139)
Query Neighborhood Hits	557	Target Neighborhood Hits	1582	Shared Neighborhood Hits	123
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

DCC_MOUSE
NC score	0.058537 (rank : 708)	θ value	3.0926 (rank : 441)
Query Neighborhood Hits	557	Target Neighborhood Hits	896	Shared Neighborhood Hits	103
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

CU030_HUMAN
NC score	0.058423 (rank : 709)	θ value	0.00509761 (rank : 186)
Query Neighborhood Hits	557	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UFM2	Gene names	C21orf30
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C21orf30.

NRX2B_HUMAN
NC score	0.058179 (rank : 710)	θ value	0.0736092 (rank : 269)
Query Neighborhood Hits	557	Target Neighborhood Hits	481	Shared Neighborhood Hits	48
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

EPHA7_MOUSE
NC score	0.058170 (rank : 711)	θ value	0.125558 (rank : 285)
Query Neighborhood Hits	557	Target Neighborhood Hits	1025	Shared Neighborhood Hits	108
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

MAP4_MOUSE
NC score	0.058111 (rank : 712)	θ value	5.27518 (rank : 498)
Query Neighborhood Hits	557	Target Neighborhood Hits	409	Shared Neighborhood Hits	79
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

RSPO1_MOUSE
NC score	0.058104 (rank : 713)	θ value	θ > 10 (rank : 883)
Query Neighborhood Hits	557	Target Neighborhood Hits	85	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

IF35_MOUSE
NC score	0.057889 (rank : 714)	θ value	θ > 10 (rank : 730)
Query Neighborhood Hits	557	Target Neighborhood Hits	210	Shared Neighborhood Hits	69
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

CSKI1_MOUSE
NC score	0.057856 (rank : 715)	θ value	θ > 10 (rank : 653)
Query Neighborhood Hits	557	Target Neighborhood Hits	1031	Shared Neighborhood Hits	142
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

HCFC2_HUMAN
NC score	0.057770 (rank : 716)	θ value	θ > 10 (rank : 724)
Query Neighborhood Hits	557	Target Neighborhood Hits	154	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y5Z7	Gene names	HCFC2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

SDK2_HUMAN
NC score	0.057726 (rank : 717)	θ value	θ > 10 (rank : 890)
Query Neighborhood Hits	557	Target Neighborhood Hits	495	Shared Neighborhood Hits	51
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SDK1_HUMAN
NC score	0.057713 (rank : 718)	θ value	θ > 10 (rank : 888)
Query Neighborhood Hits	557	Target Neighborhood Hits	511	Shared Neighborhood Hits	62
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK1_MOUSE
NC score	0.057668 (rank : 719)	θ value	θ > 10 (rank : 889)
Query Neighborhood Hits	557	Target Neighborhood Hits	495	Shared Neighborhood Hits	60
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

PGCA_MOUSE
NC score	0.057665 (rank : 720)	θ value	θ > 10 (rank : 857)
Query Neighborhood Hits	557	Target Neighborhood Hits	643	Shared Neighborhood Hits	65
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

SRRM2_MOUSE
NC score	0.057650 (rank : 721)	θ value	0.813845 (rank : 364)
Query Neighborhood Hits	557	Target Neighborhood Hits	1470	Shared Neighborhood Hits	136
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SDC3_HUMAN
NC score	0.057518 (rank : 722)	θ value	θ > 10 (rank : 886)
Query Neighborhood Hits	557	Target Neighborhood Hits	103	Shared Neighborhood Hits	48
SwissProt Accessions	O75056, Q5T1Z6, Q5T1Z7, Q96CT3, Q96PR8	Gene names	SDC3, KIAA0468
Domain Architecture
Description	Syndecan-3 (SYND3).

WASF1_HUMAN
NC score	0.057500 (rank : 723)	θ value	θ > 10 (rank : 971)
Query Neighborhood Hits	557	Target Neighborhood Hits	260	Shared Neighborhood Hits	85
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

CBP_HUMAN
NC score	0.057444 (rank : 724)	θ value	6.88961 (rank : 509)
Query Neighborhood Hits	557	Target Neighborhood Hits	941	Shared Neighborhood Hits	132
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

NEO1_HUMAN
NC score	0.057289 (rank : 725)	θ value	θ > 10 (rank : 830)
Query Neighborhood Hits	557	Target Neighborhood Hits	530	Shared Neighborhood Hits	55
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

NEO1_MOUSE
NC score	0.057201 (rank : 726)	θ value	θ > 10 (rank : 831)
Query Neighborhood Hits	557	Target Neighborhood Hits	523	Shared Neighborhood Hits	54
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

FHL2_HUMAN
NC score	0.057116 (rank : 727)	θ value	0.0193708 (rank : 219)
Query Neighborhood Hits	557	Target Neighborhood Hits	533	Shared Neighborhood Hits	51
SwissProt Accessions	Q14192, Q13229, Q13644, Q9P294	Gene names	FHL2, DRAL, SLIM3
Domain Architecture
Description	Four and a half LIM domains protein 2 (FHL-2) (Skeletal muscle LIM- protein 3) (SLIM 3) (LIM-domain protein DRAL).

CN155_HUMAN
NC score	0.056710 (rank : 728)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	557	Target Neighborhood Hits	385	Shared Neighborhood Hits	66
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

BAI2_HUMAN
NC score	0.056652 (rank : 729)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	557	Target Neighborhood Hits	332	Shared Neighborhood Hits	52
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

GP113_HUMAN
NC score	0.056634 (rank : 730)	θ value	θ > 10 (rank : 703)
Query Neighborhood Hits	557	Target Neighborhood Hits	102	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IZF5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3	Gene names	GPR113, PGR23
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 113 precursor (G-protein coupled receptor PGR23).

CSKI1_HUMAN
NC score	0.056619 (rank : 731)	θ value	θ > 10 (rank : 652)
Query Neighborhood Hits	557	Target Neighborhood Hits	997	Shared Neighborhood Hits	136
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

COKA1_HUMAN
NC score	0.056594 (rank : 732)	θ value	θ > 10 (rank : 642)
Query Neighborhood Hits	557	Target Neighborhood Hits	403	Shared Neighborhood Hits	58
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

KRA63_HUMAN
NC score	0.056455 (rank : 733)	θ value	θ > 10 (rank : 753)
Query Neighborhood Hits	557	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q3LI67	Gene names	KRTAP6-3, KAP6.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 6-3.

EDAR_HUMAN
NC score	0.056412 (rank : 734)	θ value	0.21417 (rank : 301)
Query Neighborhood Hits	557	Target Neighborhood Hits	84	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UNE0, Q9UND9	Gene names	EDAR, DL
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (EDA- A1 receptor) (Ectodermal dysplasia receptor) (Downless homolog).

LPHN1_HUMAN
NC score	0.056353 (rank : 735)	θ value	θ > 10 (rank : 779)
Query Neighborhood Hits	557	Target Neighborhood Hits	155	Shared Neighborhood Hits	24
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

SPR2I_MOUSE
NC score	0.056342 (rank : 736)	θ value	θ > 10 (rank : 911)
Query Neighborhood Hits	557	Target Neighborhood Hits	45	Shared Neighborhood Hits	21
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

ADA20_HUMAN
NC score	0.055872 (rank : 737)	θ value	θ > 10 (rank : 569)
Query Neighborhood Hits	557	Target Neighborhood Hits	143	Shared Neighborhood Hits	73
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

CLC4F_HUMAN
NC score	0.055868 (rank : 738)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	557	Target Neighborhood Hits	513	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N1N0	Gene names	CLEC4F, CLECSF13
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13).

ERBB3_MOUSE
NC score	0.055830 (rank : 739)	θ value	0.813845 (rank : 359)
Query Neighborhood Hits	557	Target Neighborhood Hits	898	Shared Neighborhood Hits	96
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

PCLO_MOUSE
NC score	0.055775 (rank : 740)	θ value	θ > 10 (rank : 853)
Query Neighborhood Hits	557	Target Neighborhood Hits	2275	Shared Neighborhood Hits	164
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

GP116_HUMAN
NC score	0.055668 (rank : 741)	θ value	θ > 10 (rank : 705)
Query Neighborhood Hits	557	Target Neighborhood Hits	167	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

PCD15_MOUSE
NC score	0.055616 (rank : 742)	θ value	θ > 10 (rank : 852)
Query Neighborhood Hits	557	Target Neighborhood Hits	262	Shared Neighborhood Hits	54
SwissProt Accessions	Q99PJ1	Gene names	Pcdh15
Domain Architecture
Description	Protocadherin-15 precursor.

C1RA_MOUSE
NC score	0.055537 (rank : 743)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	557	Target Neighborhood Hits	379	Shared Neighborhood Hits	105
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

SRRM2_HUMAN
NC score	0.055501 (rank : 744)	θ value	θ > 10 (rank : 914)
Query Neighborhood Hits	557	Target Neighborhood Hits	1296	Shared Neighborhood Hits	130
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

EPHA6_HUMAN
NC score	0.055359 (rank : 745)	θ value	2.36792 (rank : 423)
Query Neighborhood Hits	557	Target Neighborhood Hits	959	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

TNR27_HUMAN
NC score	0.055353 (rank : 746)	θ value	θ > 10 (rank : 942)
Query Neighborhood Hits	557	Target Neighborhood Hits	69	Shared Neighborhood Hits	38
SwissProt Accessions	Q9HAV5, Q6UWM2, Q8IZA6	Gene names	EDA2R, TNFRSF27, XEDAR
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

LEUK_HUMAN
NC score	0.055309 (rank : 747)	θ value	θ > 10 (rank : 777)
Query Neighborhood Hits	557	Target Neighborhood Hits	213	Shared Neighborhood Hits	49
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

WBS14_HUMAN
NC score	0.055250 (rank : 748)	θ value	θ > 10 (rank : 983)
Query Neighborhood Hits	557	Target Neighborhood Hits	273	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

LR37A_HUMAN
NC score	0.055198 (rank : 749)	θ value	4.03905 (rank : 474)
Query Neighborhood Hits	557	Target Neighborhood Hits	720	Shared Neighborhood Hits	95
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

SPR2E_HUMAN
NC score	0.055198 (rank : 750)	θ value	θ > 10 (rank : 906)
Query Neighborhood Hits	557	Target Neighborhood Hits	32	Shared Neighborhood Hits	17
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

TMPS6_HUMAN
NC score	0.055157 (rank : 751)	θ value	θ > 10 (rank : 930)
Query Neighborhood Hits	557	Target Neighborhood Hits	338	Shared Neighborhood Hits	94
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

T22D2_HUMAN
NC score	0.055034 (rank : 752)	θ value	θ > 10 (rank : 915)
Query Neighborhood Hits	557	Target Neighborhood Hits	250	Shared Neighborhood Hits	65
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

CPSF6_MOUSE
NC score	0.055008 (rank : 753)	θ value	θ > 10 (rank : 645)
Query Neighborhood Hits	557	Target Neighborhood Hits	356	Shared Neighborhood Hits	69
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CRDL2_HUMAN
NC score	0.054945 (rank : 754)	θ value	θ > 10 (rank : 649)
Query Neighborhood Hits	557	Target Neighborhood Hits	99	Shared Neighborhood Hits	34
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

LPHN2_HUMAN
NC score	0.054859 (rank : 755)	θ value	θ > 10 (rank : 780)
Query Neighborhood Hits	557	Target Neighborhood Hits	136	Shared Neighborhood Hits	14
SwissProt Accessions	O95490, O94882, Q5VX76, Q9UKY5, Q9UKY6	Gene names	LPHN2, KIAA0786, LEC1, LPHH1
Domain Architecture
Description	Latrophilin-2 precursor (Calcium-independent alpha-latrotoxin receptor 2) (Latrophilin homolog 1) (Lectomedin-1).

FMNL_HUMAN
NC score	0.054842 (rank : 756)	θ value	θ > 10 (rank : 691)
Query Neighborhood Hits	557	Target Neighborhood Hits	529	Shared Neighborhood Hits	93
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

GP125_HUMAN
NC score	0.054664 (rank : 757)	θ value	θ > 10 (rank : 709)
Query Neighborhood Hits	557	Target Neighborhood Hits	327	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

DSCL1_HUMAN
NC score	0.054658 (rank : 758)	θ value	θ > 10 (rank : 665)
Query Neighborhood Hits	557	Target Neighborhood Hits	589	Shared Neighborhood Hits	75
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

C1RB_MOUSE
NC score	0.054644 (rank : 759)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	557	Target Neighborhood Hits	380	Shared Neighborhood Hits	105
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

SDC3_MOUSE
NC score	0.054442 (rank : 760)	θ value	θ > 10 (rank : 887)
Query Neighborhood Hits	557	Target Neighborhood Hits	107	Shared Neighborhood Hits	49
SwissProt Accessions	Q64519, Q3UDD9, Q6ZQA4, Q7TQD4	Gene names	Sdc3, Kiaa0468
Domain Architecture
Description	Syndecan-3 precursor (SYND3).

DCC_HUMAN
NC score	0.054190 (rank : 761)	θ value	θ > 10 (rank : 660)
Query Neighborhood Hits	557	Target Neighborhood Hits	583	Shared Neighborhood Hits	67
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

NUMA1_HUMAN
NC score	0.054178 (rank : 762)	θ value	θ > 10 (rank : 846)
Query Neighborhood Hits	557	Target Neighborhood Hits	1523	Shared Neighborhood Hits	52
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

EPHB3_HUMAN
NC score	0.054115 (rank : 763)	θ value	1.81305 (rank : 402)
Query Neighborhood Hits	557	Target Neighborhood Hits	996	Shared Neighborhood Hits	93
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

EPHA6_MOUSE
NC score	0.054059 (rank : 764)	θ value	θ > 10 (rank : 680)
Query Neighborhood Hits	557	Target Neighborhood Hits	946	Shared Neighborhood Hits	86
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

PO121_MOUSE
NC score	0.053970 (rank : 765)	θ value	θ > 10 (rank : 867)
Query Neighborhood Hits	557	Target Neighborhood Hits	345	Shared Neighborhood Hits	75
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

CIC_HUMAN
NC score	0.053960 (rank : 766)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	557	Target Neighborhood Hits	992	Shared Neighborhood Hits	130
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

LPHN3_HUMAN
NC score	0.053889 (rank : 767)	θ value	θ > 10 (rank : 781)
Query Neighborhood Hits	557	Target Neighborhood Hits	139	Shared Neighborhood Hits	13
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

PCD15_HUMAN
NC score	0.053853 (rank : 768)	θ value	θ > 10 (rank : 851)
Query Neighborhood Hits	557	Target Neighborhood Hits	289	Shared Neighborhood Hits	51
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

GP124_MOUSE
NC score	0.053851 (rank : 769)	θ value	θ > 10 (rank : 708)
Query Neighborhood Hits	557	Target Neighborhood Hits	423	Shared Neighborhood Hits	33
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

MAP4_HUMAN
NC score	0.053767 (rank : 770)	θ value	θ > 10 (rank : 796)
Query Neighborhood Hits	557	Target Neighborhood Hits	428	Shared Neighborhood Hits	76
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

WASP_MOUSE
NC score	0.053746 (rank : 771)	θ value	θ > 10 (rank : 980)
Query Neighborhood Hits	557	Target Neighborhood Hits	223	Shared Neighborhood Hits	59
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

CPSF6_HUMAN
NC score	0.053672 (rank : 772)	θ value	θ > 10 (rank : 644)
Query Neighborhood Hits	557	Target Neighborhood Hits	359	Shared Neighborhood Hits	68
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

MCSP_HUMAN
NC score	0.053658 (rank : 773)	θ value	θ > 10 (rank : 801)
Query Neighborhood Hits	557	Target Neighborhood Hits	48	Shared Neighborhood Hits	26
SwissProt Accessions	P49901, Q96A42	Gene names	SMCP, MCS, MCSP
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

HBEGF_HUMAN
NC score	0.053554 (rank : 774)	θ value	θ > 10 (rank : 723)
Query Neighborhood Hits	557	Target Neighborhood Hits	61	Shared Neighborhood Hits	38
SwissProt Accessions	Q99075	Gene names	HBEGF, DTR, HEGFL
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF) (Diphtheria toxin receptor) (DT-R).

EDAR_MOUSE
NC score	0.053449 (rank : 775)	θ value	0.279714 (rank : 311)
Query Neighborhood Hits	557	Target Neighborhood Hits	66	Shared Neighborhood Hits	27
SwissProt Accessions	Q9R187, Q9DC43	Gene names	Edar, Dl
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (Ectodermal dysplasia receptor) (Downless).

DGKK_HUMAN
NC score	0.053443 (rank : 776)	θ value	θ > 10 (rank : 661)
Query Neighborhood Hits	557	Target Neighborhood Hits	378	Shared Neighborhood Hits	83
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

PARM1_HUMAN
NC score	0.053414 (rank : 777)	θ value	θ > 10 (rank : 850)
Query Neighborhood Hits	557	Target Neighborhood Hits	86	Shared Neighborhood Hits	32
SwissProt Accessions	Q6UWI2, Q96DV8, Q9Y4S1	Gene names	ames=UNQ1879/PRO4322
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

GP124_HUMAN
NC score	0.053367 (rank : 778)	θ value	θ > 10 (rank : 707)
Query Neighborhood Hits	557	Target Neighborhood Hits	304	Shared Neighborhood Hits	24
SwissProt Accessions	Q96PE1, Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4	Gene names	GPR124, KIAA1531, TEM5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

SFPQ_MOUSE
NC score	0.053060 (rank : 779)	θ value	θ > 10 (rank : 897)
Query Neighborhood Hits	557	Target Neighborhood Hits	958	Shared Neighborhood Hits	112
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

K0319_HUMAN
NC score	0.053001 (rank : 780)	θ value	0.279714 (rank : 313)
Query Neighborhood Hits	557	Target Neighborhood Hits	154	Shared Neighborhood Hits	36
SwissProt Accessions	Q5VV43, Q9UJC8, Q9Y4G7	Gene names	KIAA0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

TR10B_HUMAN
NC score	0.052814 (rank : 781)	θ value	θ > 10 (rank : 955)
Query Neighborhood Hits	557	Target Neighborhood Hits	71	Shared Neighborhood Hits	42
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

ALEX_HUMAN
NC score	0.052788 (rank : 782)	θ value	θ > 10 (rank : 582)
Query Neighborhood Hits	557	Target Neighborhood Hits	361	Shared Neighborhood Hits	79
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

TGFA_HUMAN
NC score	0.052781 (rank : 783)	θ value	θ > 10 (rank : 925)
Query Neighborhood Hits	557	Target Neighborhood Hits	61	Shared Neighborhood Hits	38
SwissProt Accessions	P01135, Q15577	Gene names	TGFA
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

LCE3E_HUMAN
NC score	0.052734 (rank : 784)	θ value	θ > 10 (rank : 772)
Query Neighborhood Hits	557	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q5T5B0	Gene names	LCE3E, LEP17
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3E (Late envelope protein 17).

FURIN_MOUSE
NC score	0.052542 (rank : 785)	θ value	θ > 10 (rank : 699)
Query Neighborhood Hits	557	Target Neighborhood Hits	49	Shared Neighborhood Hits	19
SwissProt Accessions	P23188	Gene names	Furin, Fur, Pcsk3
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme) (Prohormone convertase 3).

FURIN_HUMAN
NC score	0.052511 (rank : 786)	θ value	θ > 10 (rank : 698)
Query Neighborhood Hits	557	Target Neighborhood Hits	52	Shared Neighborhood Hits	22
SwissProt Accessions	P09958, Q14336, Q6LBS3	Gene names	FURIN, FUR, PACE
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme).

EREG_MOUSE
NC score	0.052503 (rank : 787)	θ value	θ > 10 (rank : 683)
Query Neighborhood Hits	557	Target Neighborhood Hits	65	Shared Neighborhood Hits	34
SwissProt Accessions	Q61521, Q7M0A8	Gene names	Ereg
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

KR261_HUMAN
NC score	0.052489 (rank : 788)	θ value	θ > 10 (rank : 743)
Query Neighborhood Hits	557	Target Neighborhood Hits	65	Shared Neighborhood Hits	31
SwissProt Accessions	Q6PEX3	Gene names	KRTAP26-1, KAP26.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 26-1.

CTGF_HUMAN
NC score	0.052470 (rank : 789)	θ value	θ > 10 (rank : 657)
Query Neighborhood Hits	557	Target Neighborhood Hits	128	Shared Neighborhood Hits	50
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

EGFR_MOUSE
NC score	0.052408 (rank : 790)	θ value	0.279714 (rank : 312)
Query Neighborhood Hits	557	Target Neighborhood Hits	927	Shared Neighborhood Hits	108
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

GP179_HUMAN
NC score	0.052394 (rank : 791)	θ value	θ > 10 (rank : 715)
Query Neighborhood Hits	557	Target Neighborhood Hits	372	Shared Neighborhood Hits	71
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

EPHB1_HUMAN
NC score	0.052208 (rank : 792)	θ value	0.62314 (rank : 351)
Query Neighborhood Hits	557	Target Neighborhood Hits	988	Shared Neighborhood Hits	111
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

LCE3C_HUMAN
NC score	0.052196 (rank : 793)	θ value	θ > 10 (rank : 771)
Query Neighborhood Hits	557	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	Q5T5A8	Gene names	LCE3C, LEP15, SPRL3A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A).

ZN330_HUMAN
NC score	0.052194 (rank : 794)	θ value	θ > 10 (rank : 990)
Query Neighborhood Hits	557	Target Neighborhood Hits	83	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y3S2	Gene names	ZNF330, NOA36
Domain Architecture	No domain graphic available
Description	Zinc finger protein 330 (Nucleolar cysteine-rich protein) (Nucleolar autoantigen 36).

ERBB2_HUMAN
NC score	0.052183 (rank : 795)	θ value	1.81305 (rank : 403)
Query Neighborhood Hits	557	Target Neighborhood Hits	1073	Shared Neighborhood Hits	108
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

EPGN_HUMAN
NC score	0.052126 (rank : 796)	θ value	θ > 10 (rank : 677)
Query Neighborhood Hits	557	Target Neighborhood Hits	59	Shared Neighborhood Hits	35
SwissProt Accessions	Q6UW88	Gene names	EPGN
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

SPR2D_HUMAN
NC score	0.052029 (rank : 797)	θ value	θ > 10 (rank : 904)
Query Neighborhood Hits	557	Target Neighborhood Hits	30	Shared Neighborhood Hits	16
SwissProt Accessions	P22532, Q5T523, Q96RM3	Gene names	SPRR2D
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D (SPR-2D) (Small proline-rich protein II) (SPR-II).

CCNK_MOUSE
NC score	0.051915 (rank : 798)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	557	Target Neighborhood Hits	350	Shared Neighborhood Hits	81
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

HPLN2_MOUSE
NC score	0.051660 (rank : 799)	θ value	θ > 10 (rank : 728)
Query Neighborhood Hits	557	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ESM3	Gene names	Hapln2, Bral1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

SF01_HUMAN
NC score	0.051526 (rank : 800)	θ value	θ > 10 (rank : 894)
Query Neighborhood Hits	557	Target Neighborhood Hits	287	Shared Neighborhood Hits	70
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

EPHA5_HUMAN
NC score	0.051516 (rank : 801)	θ value	θ > 10 (rank : 679)
Query Neighborhood Hits	557	Target Neighborhood Hits	1009	Shared Neighborhood Hits	84
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

SPR2E_MOUSE
NC score	0.051192 (rank : 802)	θ value	θ > 10 (rank : 907)
Query Neighborhood Hits	557	Target Neighborhood Hits	45	Shared Neighborhood Hits	17
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

PCSK4_HUMAN
NC score	0.051192 (rank : 803)	θ value	θ > 10 (rank : 854)
Query Neighborhood Hits	557	Target Neighborhood Hits	32	Shared Neighborhood Hits	15
SwissProt Accessions	Q6UW60, Q8IY88, Q9UF79	Gene names	PCSK4, PC4
Domain Architecture	No domain graphic available
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (Proprotein convertase PC4).

CRDL1_HUMAN
NC score	0.051165 (rank : 804)	θ value	θ > 10 (rank : 648)
Query Neighborhood Hits	557	Target Neighborhood Hits	75	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BU40, Q9Y3H7	Gene names	CHRDL1, NRLN1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CAD23_MOUSE
NC score	0.051159 (rank : 805)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	557	Target Neighborhood Hits	208	Shared Neighborhood Hits	18
SwissProt Accessions	Q99PF4, Q99NH1, Q9D4N9	Gene names	Cdh23
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

GOGA1_HUMAN
NC score	0.051057 (rank : 806)	θ value	θ > 10 (rank : 702)
Query Neighborhood Hits	557	Target Neighborhood Hits	1222	Shared Neighborhood Hits	36
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

EPHA4_MOUSE
NC score	0.051046 (rank : 807)	θ value	2.36792 (rank : 422)
Query Neighborhood Hits	557	Target Neighborhood Hits	982	Shared Neighborhood Hits	92
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

EP300_HUMAN
NC score	0.050884 (rank : 808)	θ value	θ > 10 (rank : 676)
Query Neighborhood Hits	557	Target Neighborhood Hits	821	Shared Neighborhood Hits	121
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

CAD23_HUMAN
NC score	0.050882 (rank : 809)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	557	Target Neighborhood Hits	197	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H251, Q6UWW1, Q9H4K9	Gene names	CDH23, KIAA1774
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

TMPS6_MOUSE
NC score	0.050809 (rank : 810)	θ value	θ > 10 (rank : 931)
Query Neighborhood Hits	557	Target Neighborhood Hits	341	Shared Neighborhood Hits	92
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

HPLN2_HUMAN
NC score	0.050798 (rank : 811)	θ value	θ > 10 (rank : 727)
Query Neighborhood Hits	557	Target Neighborhood Hits	80	Shared Neighborhood Hits	12
SwissProt Accessions	Q9GZV7	Gene names	HAPLN2, BRAL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

GP125_MOUSE
NC score	0.050750 (rank : 812)	θ value	θ > 10 (rank : 710)
Query Neighborhood Hits	557	Target Neighborhood Hits	329	Shared Neighborhood Hits	22
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

CLC4F_MOUSE
NC score	0.050621 (rank : 813)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	557	Target Neighborhood Hits	572	Shared Neighborhood Hits	32
SwissProt Accessions	P70194, Q8BLZ8	Gene names	Clec4f, Clecsf13, Kclr
Domain Architecture
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13) (Kupffer cell receptor).

GP114_HUMAN
NC score	0.050530 (rank : 814)	θ value	θ > 10 (rank : 704)
Query Neighborhood Hits	557	Target Neighborhood Hits	75	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IZF4, Q6ZMH7, Q6ZML4, Q86SL8, Q8IZ14	Gene names	GPR114, PGR27
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 114 precursor (G-protein coupled receptor PGR27).

SHAN1_HUMAN
NC score	0.050430 (rank : 815)	θ value	θ > 10 (rank : 898)
Query Neighborhood Hits	557	Target Neighborhood Hits	1041	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

IDD_HUMAN
NC score	0.050362 (rank : 816)	θ value	θ > 10 (rank : 729)
Query Neighborhood Hits	557	Target Neighborhood Hits	127	Shared Neighborhood Hits	33
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

PI5PA_MOUSE
NC score	0.050357 (rank : 817)	θ value	θ > 10 (rank : 865)
Query Neighborhood Hits	557	Target Neighborhood Hits	331	Shared Neighborhood Hits	76
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

EGFR_HUMAN
NC score	0.050330 (rank : 818)	θ value	θ > 10 (rank : 669)
Query Neighborhood Hits	557	Target Neighborhood Hits	939	Shared Neighborhood Hits	102
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

EPHA4_HUMAN
NC score	0.050329 (rank : 819)	θ value	2.36792 (rank : 421)
Query Neighborhood Hits	557	Target Neighborhood Hits	975	Shared Neighborhood Hits	86
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

DSCAM_HUMAN
NC score	0.050265 (rank : 820)	θ value	θ > 10 (rank : 664)
Query Neighborhood Hits	557	Target Neighborhood Hits	524	Shared Neighborhood Hits	47
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

CEL_HUMAN
NC score	0.050237 (rank : 821)	θ value	0.00020696 (rank : 145)
Query Neighborhood Hits	557	Target Neighborhood Hits	896	Shared Neighborhood Hits	96
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

GP123_HUMAN
NC score	0.050091 (rank : 822)	θ value	θ > 10 (rank : 706)
Query Neighborhood Hits	557	Target Neighborhood Hits	120	Shared Neighborhood Hits	13
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

EPHB3_MOUSE
NC score	0.049563 (rank : 823)	θ value	5.27518 (rank : 490)
Query Neighborhood Hits	557	Target Neighborhood Hits	996	Shared Neighborhood Hits	84
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

CIZ1_HUMAN
NC score	0.049554 (rank : 824)	θ value	0.125558 (rank : 283)
Query Neighborhood Hits	557	Target Neighborhood Hits	359	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

K0319_MOUSE
NC score	0.049142 (rank : 825)	θ value	0.163984 (rank : 296)
Query Neighborhood Hits	557	Target Neighborhood Hits	134	Shared Neighborhood Hits	31
SwissProt Accessions	Q5SZV5, Q80U39	Gene names	Kiaa0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

ERBB2_MOUSE
NC score	0.048706 (rank : 826)	θ value	2.36792 (rank : 424)
Query Neighborhood Hits	557	Target Neighborhood Hits	918	Shared Neighborhood Hits	92
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

K1802_HUMAN
NC score	0.047827 (rank : 827)	θ value	4.03905 (rank : 473)
Query Neighborhood Hits	557	Target Neighborhood Hits	1378	Shared Neighborhood Hits	143
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

RGS3_MOUSE
NC score	0.047418 (rank : 828)	θ value	3.0926 (rank : 457)
Query Neighborhood Hits	557	Target Neighborhood Hits	1621	Shared Neighborhood Hits	133
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

PER3_HUMAN
NC score	0.047188 (rank : 829)	θ value	0.0563607 (rank : 255)
Query Neighborhood Hits	557	Target Neighborhood Hits	479	Shared Neighborhood Hits	71
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

CABIN_HUMAN
NC score	0.046578 (rank : 830)	θ value	5.27518 (rank : 487)
Query Neighborhood Hits	557	Target Neighborhood Hits	490	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

BCL9_HUMAN
NC score	0.045880 (rank : 831)	θ value	0.279714 (rank : 310)
Query Neighborhood Hits	557	Target Neighborhood Hits	1008	Shared Neighborhood Hits	101
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

FA47A_HUMAN
NC score	0.045240 (rank : 832)	θ value	1.38821 (rank : 386)
Query Neighborhood Hits	557	Target Neighborhood Hits	451	Shared Neighborhood Hits	53
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

NPAS4_HUMAN
NC score	0.044310 (rank : 833)	θ value	0.0563607 (rank : 254)
Query Neighborhood Hits	557	Target Neighborhood Hits	214	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

NPAS4_MOUSE
NC score	0.044228 (rank : 834)	θ value	0.0330416 (rank : 242)
Query Neighborhood Hits	557	Target Neighborhood Hits	245	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

FA47B_HUMAN
NC score	0.044106 (rank : 835)	θ value	0.21417 (rank : 302)
Query Neighborhood Hits	557	Target Neighborhood Hits	431	Shared Neighborhood Hits	60
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

PF21B_MOUSE
NC score	0.042830 (rank : 836)	θ value	0.0193708 (rank : 222)
Query Neighborhood Hits	557	Target Neighborhood Hits	278	Shared Neighborhood Hits	51
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

EP400_HUMAN
NC score	0.042810 (rank : 837)	θ value	1.38821 (rank : 385)
Query Neighborhood Hits	557	Target Neighborhood Hits	556	Shared Neighborhood Hits	107
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

SAPS1_HUMAN
NC score	0.042601 (rank : 838)	θ value	0.365318 (rank : 331)
Query Neighborhood Hits	557	Target Neighborhood Hits	704	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

TITIN_HUMAN
NC score	0.042201 (rank : 839)	θ value	8.99809 (rank : 555)
Query Neighborhood Hits	557	Target Neighborhood Hits	2923	Shared Neighborhood Hits	175
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

LPP_HUMAN
NC score	0.041828 (rank : 840)	θ value	0.0330416 (rank : 241)
Query Neighborhood Hits	557	Target Neighborhood Hits	775	Shared Neighborhood Hits	89
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

EP400_MOUSE
NC score	0.041703 (rank : 841)	θ value	0.47712 (rank : 341)
Query Neighborhood Hits	557	Target Neighborhood Hits	592	Shared Neighborhood Hits	93
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

TAU_MOUSE
NC score	0.041546 (rank : 842)	θ value	1.81305 (rank : 412)
Query Neighborhood Hits	557	Target Neighborhood Hits	502	Shared Neighborhood Hits	71
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

PROP_MOUSE
NC score	0.040716 (rank : 843)	θ value	6.88961 (rank : 528)
Query Neighborhood Hits	557	Target Neighborhood Hits	165	Shared Neighborhood Hits	44
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

ATX2_MOUSE
NC score	0.040006 (rank : 844)	θ value	2.36792 (rank : 420)
Query Neighborhood Hits	557	Target Neighborhood Hits	445	Shared Neighborhood Hits	71
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

TARA_HUMAN
NC score	0.039781 (rank : 845)	θ value	1.38821 (rank : 392)
Query Neighborhood Hits	557	Target Neighborhood Hits	1626	Shared Neighborhood Hits	114
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ATF6B_HUMAN
NC score	0.039584 (rank : 846)	θ value	0.00175202 (rank : 170)
Query Neighborhood Hits	557	Target Neighborhood Hits	122	Shared Neighborhood Hits	18
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).

ANK2_HUMAN
NC score	0.039579 (rank : 847)	θ value	0.0252991 (rank : 227)
Query Neighborhood Hits	557	Target Neighborhood Hits	1615	Shared Neighborhood Hits	114
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

K1683_HUMAN
NC score	0.039534 (rank : 848)	θ value	4.03905 (rank : 472)
Query Neighborhood Hits	557	Target Neighborhood Hits	240	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

FHL1_MOUSE
NC score	0.038781 (rank : 849)	θ value	0.813845 (rank : 361)
Query Neighborhood Hits	557	Target Neighborhood Hits	462	Shared Neighborhood Hits	36
SwissProt Accessions	P97447, O55181, Q8K318	Gene names	Fhl1
Domain Architecture
Description	Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle LIM- protein 1) (SLIM 1) (SLIM) (KyoT) (RBP-associated molecule 14-1) (RAM14-1).

SFRS8_HUMAN
NC score	0.038195 (rank : 850)	θ value	2.36792 (rank : 432)
Query Neighborhood Hits	557	Target Neighborhood Hits	166	Shared Neighborhood Hits	27
SwissProt Accessions	Q12872	Gene names	SFRS8, SWAP
Domain Architecture
Description	Splicing factor, arginine/serine-rich 8 (Suppressor of white apricot protein homolog).

GP1BA_HUMAN
NC score	0.038153 (rank : 851)	θ value	6.88961 (rank : 520)
Query Neighborhood Hits	557	Target Neighborhood Hits	407	Shared Neighborhood Hits	60
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

K1802_MOUSE
NC score	0.038110 (rank : 852)	θ value	0.365318 (rank : 325)
Query Neighborhood Hits	557	Target Neighborhood Hits	1596	Shared Neighborhood Hits	134
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

YETS2_MOUSE
NC score	0.037951 (rank : 853)	θ value	0.21417 (rank : 308)
Query Neighborhood Hits	557	Target Neighborhood Hits	278	Shared Neighborhood Hits	44
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

FHL1_HUMAN
NC score	0.036837 (rank : 854)	θ value	1.81305 (rank : 404)
Query Neighborhood Hits	557	Target Neighborhood Hits	436	Shared Neighborhood Hits	34
SwissProt Accessions	Q13642, O95212, Q13230, Q13645, Q5M7Y6, Q9NZ40, Q9UKZ8, Q9Y630	Gene names	FHL1, SLIM1
Domain Architecture
Description	Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle LIM- protein 1) (SLIM 1) (SLIM).

SC24C_HUMAN
NC score	0.036354 (rank : 855)	θ value	3.0926 (rank : 458)
Query Neighborhood Hits	557	Target Neighborhood Hits	662	Shared Neighborhood Hits	70
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SPR1B_MOUSE
NC score	0.035810 (rank : 856)	θ value	0.279714 (rank : 318)
Query Neighborhood Hits	557	Target Neighborhood Hits	395	Shared Neighborhood Hits	53
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

SPR1A_MOUSE
NC score	0.035746 (rank : 857)	θ value	1.81305 (rank : 411)
Query Neighborhood Hits	557	Target Neighborhood Hits	343	Shared Neighborhood Hits	45
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

RTP3_MOUSE
NC score	0.034364 (rank : 858)	θ value	8.99809 (rank : 554)
Query Neighborhood Hits	557	Target Neighborhood Hits	374	Shared Neighborhood Hits	71
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

MINT_MOUSE
NC score	0.032932 (rank : 859)	θ value	1.06291 (rank : 375)
Query Neighborhood Hits	557	Target Neighborhood Hits	1514	Shared Neighborhood Hits	116
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

DAF1_MOUSE
NC score	0.032912 (rank : 860)	θ value	1.38821 (rank : 383)
Query Neighborhood Hits	557	Target Neighborhood Hits	204	Shared Neighborhood Hits	38
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

ATX7_HUMAN
NC score	0.032044 (rank : 861)	θ value	4.03905 (rank : 465)
Query Neighborhood Hits	557	Target Neighborhood Hits	351	Shared Neighborhood Hits	50
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

PSL1_HUMAN
NC score	0.031863 (rank : 862)	θ value	0.365318 (rank : 330)
Query Neighborhood Hits	557	Target Neighborhood Hits	650	Shared Neighborhood Hits	56
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

GRIN1_HUMAN
NC score	0.030856 (rank : 863)	θ value	6.88961 (rank : 521)
Query Neighborhood Hits	557	Target Neighborhood Hits	681	Shared Neighborhood Hits	64
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

EMSY_MOUSE
NC score	0.030426 (rank : 864)	θ value	8.99809 (rank : 543)
Query Neighborhood Hits	557	Target Neighborhood Hits	294	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

TAF9_HUMAN
NC score	0.029677 (rank : 865)	θ value	0.47712 (rank : 349)
Query Neighborhood Hits	557	Target Neighborhood Hits	41	Shared Neighborhood Hits	14
SwissProt Accessions	Q16594, Q9BTS1	Gene names	TAF9, TAF2G, TAFII31
Domain Architecture
Description	Transcription initiation factor TFIID subunit 9 (Transcription initiation factor TFIID 31 kDa subunit) (TAFII-31) (TAFII-32) (TAFII32) (STAF31/32).

AMPH_HUMAN
NC score	0.029520 (rank : 866)	θ value	4.03905 (rank : 463)
Query Neighborhood Hits	557	Target Neighborhood Hits	455	Shared Neighborhood Hits	55
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

TP53B_MOUSE
NC score	0.029225 (rank : 867)	θ value	1.81305 (rank : 415)
Query Neighborhood Hits	557	Target Neighborhood Hits	644	Shared Neighborhood Hits	65
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TRML2_HUMAN
NC score	0.029212 (rank : 868)	θ value	0.125558 (rank : 294)
Query Neighborhood Hits	557	Target Neighborhood Hits	54	Shared Neighborhood Hits	7
SwissProt Accessions	Q5T2D2, Q8IWY0, Q9H8E9	Gene names	TREML2, C6orf76, TLT2
Domain Architecture	No domain graphic available
Description	Trem-like transcript 2 protein precursor (TLT-2) (Triggering receptor expressed on myeloid cells-like protein 2).

X3CL1_HUMAN
NC score	0.029144 (rank : 869)	θ value	0.279714 (rank : 321)
Query Neighborhood Hits	557	Target Neighborhood Hits	152	Shared Neighborhood Hits	21
SwissProt Accessions	P78423, O00672	Gene names	CX3CL1, A-152E5.2, FKN, NTT, SCYD1
Domain Architecture
Description	Fractalkine precursor (CX3CL1) (Neurotactin) (CX3C membrane-anchored chemokine) (Small inducible cytokine D1).

GA2L2_MOUSE
NC score	0.028764 (rank : 870)	θ value	0.125558 (rank : 289)
Query Neighborhood Hits	557	Target Neighborhood Hits	395	Shared Neighborhood Hits	52
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

PF21A_HUMAN
NC score	0.028706 (rank : 871)	θ value	0.125558 (rank : 293)
Query Neighborhood Hits	557	Target Neighborhood Hits	303	Shared Neighborhood Hits	27
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

MUCEN_MOUSE
NC score	0.028375 (rank : 872)	θ value	2.36792 (rank : 428)
Query Neighborhood Hits	557	Target Neighborhood Hits	65	Shared Neighborhood Hits	15
SwissProt Accessions	Q9R0H2, Q78KL2, Q9DCN9, Q9ULC1, Q9Z2I1	Gene names	Emcn, Muc14
Domain Architecture	No domain graphic available
Description	Endomucin precursor (Endomucin-1/2).

ATX7_MOUSE
NC score	0.028326 (rank : 873)	θ value	1.81305 (rank : 397)
Query Neighborhood Hits	557	Target Neighborhood Hits	328	Shared Neighborhood Hits	48
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

LMO6_HUMAN
NC score	0.028315 (rank : 874)	θ value	3.0926 (rank : 451)
Query Neighborhood Hits	557	Target Neighborhood Hits	337	Shared Neighborhood Hits	30
SwissProt Accessions	O43900, O76007	Gene names	LMO6
Domain Architecture
Description	LIM domain only protein 6 (Triple LIM domain protein 6).

TAF9_MOUSE
NC score	0.028300 (rank : 875)	θ value	0.365318 (rank : 333)
Query Neighborhood Hits	557	Target Neighborhood Hits	69	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VI33, Q32P09, Q80XS3, Q9CV61	Gene names	Taf9, Taf2g
Domain Architecture
Description	Transcription initiation factor TFIID subunit 9 (Transcription initiation factor TFIID 31 kDa subunit) (TAFII-31) (TAFII-32) (TAFII32).

NFH_MOUSE
NC score	0.027288 (rank : 876)	θ value	1.81305 (rank : 407)
Query Neighborhood Hits	557	Target Neighborhood Hits	2247	Shared Neighborhood Hits	124
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RGS3_HUMAN
NC score	0.027089 (rank : 877)	θ value	1.06291 (rank : 379)
Query Neighborhood Hits	557	Target Neighborhood Hits	1375	Shared Neighborhood Hits	103
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

BAZ2A_MOUSE
NC score	0.025943 (rank : 878)	θ value	1.81305 (rank : 398)
Query Neighborhood Hits	557	Target Neighborhood Hits	744	Shared Neighborhood Hits	75
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BCAR1_HUMAN
NC score	0.025194 (rank : 879)	θ value	0.0961366 (rank : 274)
Query Neighborhood Hits	557	Target Neighborhood Hits	554	Shared Neighborhood Hits	57
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

WNK2_HUMAN
NC score	0.025191 (rank : 880)	θ value	0.0148317 (rank : 215)
Query Neighborhood Hits	557	Target Neighborhood Hits	1407	Shared Neighborhood Hits	149
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

SETD2_HUMAN
NC score	0.024855 (rank : 881)	θ value	4.03905 (rank : 480)
Query Neighborhood Hits	557	Target Neighborhood Hits	412	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

MAGD4_HUMAN
NC score	0.024522 (rank : 882)	θ value	0.279714 (rank : 315)
Query Neighborhood Hits	557	Target Neighborhood Hits	338	Shared Neighborhood Hits	57
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

T22D4_HUMAN
NC score	0.024516 (rank : 883)	θ value	6.88961 (rank : 534)
Query Neighborhood Hits	557	Target Neighborhood Hits	403	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

MTSS1_MOUSE
NC score	0.024510 (rank : 884)	θ value	8.99809 (rank : 552)
Query Neighborhood Hits	557	Target Neighborhood Hits	592	Shared Neighborhood Hits	56
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

ATS12_MOUSE
NC score	0.024493 (rank : 885)	θ value	4.03905 (rank : 464)
Query Neighborhood Hits	557	Target Neighborhood Hits	220	Shared Neighborhood Hits	54
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

DIDO1_HUMAN
NC score	0.024391 (rank : 886)	θ value	6.88961 (rank : 513)
Query Neighborhood Hits	557	Target Neighborhood Hits	960	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

DOK7_MOUSE
NC score	0.024276 (rank : 887)	θ value	0.47712 (rank : 340)
Query Neighborhood Hits	557	Target Neighborhood Hits	169	Shared Neighborhood Hits	22
SwissProt Accessions	Q18PE0, Q3TCZ6, Q5FW70, Q8C8U7	Gene names	Dok7
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

SPEG_HUMAN
NC score	0.024130 (rank : 888)	θ value	6.88961 (rank : 533)
Query Neighborhood Hits	557	Target Neighborhood Hits	1762	Shared Neighborhood Hits	154
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

OBF1_HUMAN
NC score	0.023428 (rank : 889)	θ value	1.06291 (rank : 377)
Query Neighborhood Hits	557	Target Neighborhood Hits	203	Shared Neighborhood Hits	26
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

SPEG_MOUSE
NC score	0.022947 (rank : 890)	θ value	1.38821 (rank : 390)
Query Neighborhood Hits	557	Target Neighborhood Hits	1959	Shared Neighborhood Hits	150
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

RIMB1_MOUSE
NC score	0.022890 (rank : 891)	θ value	6.88961 (rank : 529)
Query Neighborhood Hits	557	Target Neighborhood Hits	1376	Shared Neighborhood Hits	63
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SH23A_HUMAN
NC score	0.022439 (rank : 892)	θ value	0.0252991 (rank : 236)
Query Neighborhood Hits	557	Target Neighborhood Hits	149	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BRG2, Q9Y2X4	Gene names	SH2D3A, NSP1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3A (Novel SH2-containing protein 1).

SEPT9_HUMAN
NC score	0.021501 (rank : 893)	θ value	0.365318 (rank : 332)
Query Neighborhood Hits	557	Target Neighborhood Hits	706	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

CASC3_MOUSE
NC score	0.021271 (rank : 894)	θ value	6.88961 (rank : 508)
Query Neighborhood Hits	557	Target Neighborhood Hits	333	Shared Neighborhood Hits	43
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

GON4L_MOUSE
NC score	0.021237 (rank : 895)	θ value	3.0926 (rank : 446)
Query Neighborhood Hits	557	Target Neighborhood Hits	455	Shared Neighborhood Hits	51
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

HSF1_MOUSE
NC score	0.021192 (rank : 896)	θ value	1.06291 (rank : 371)
Query Neighborhood Hits	557	Target Neighborhood Hits	267	Shared Neighborhood Hits	25
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

BCAR1_MOUSE
NC score	0.021116 (rank : 897)	θ value	6.88961 (rank : 507)
Query Neighborhood Hits	557	Target Neighborhood Hits	438	Shared Neighborhood Hits	48
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

PER2_MOUSE
NC score	0.020802 (rank : 898)	θ value	0.62314 (rank : 355)
Query Neighborhood Hits	557	Target Neighborhood Hits	325	Shared Neighborhood Hits	30
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

IQEC3_MOUSE
NC score	0.020624 (rank : 899)	θ value	0.47712 (rank : 344)
Query Neighborhood Hits	557	Target Neighborhood Hits	274	Shared Neighborhood Hits	41
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

HNF1A_HUMAN
NC score	0.020362 (rank : 900)	θ value	4.03905 (rank : 469)
Query Neighborhood Hits	557	Target Neighborhood Hits	193	Shared Neighborhood Hits	31
SwissProt Accessions	P20823, Q99861	Gene names	TCF1, HNF1A
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1) (Transcription factor 1) (TCF-1).

RUSC2_MOUSE
NC score	0.020181 (rank : 901)	θ value	1.81305 (rank : 409)
Query Neighborhood Hits	557	Target Neighborhood Hits	305	Shared Neighborhood Hits	43
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SSBP4_HUMAN
NC score	0.020024 (rank : 902)	θ value	0.21417 (rank : 307)
Query Neighborhood Hits	557	Target Neighborhood Hits	753	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

TMPS9_MOUSE
NC score	0.019673 (rank : 903)	θ value	0.365318 (rank : 335)
Query Neighborhood Hits	557	Target Neighborhood Hits	296	Shared Neighborhood Hits	43
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

TMPS9_HUMAN
NC score	0.019581 (rank : 904)	θ value	0.365318 (rank : 334)
Query Neighborhood Hits	557	Target Neighborhood Hits	276	Shared Neighborhood Hits	35
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

REXO1_HUMAN
NC score	0.019578 (rank : 905)	θ value	4.03905 (rank : 477)
Query Neighborhood Hits	557	Target Neighborhood Hits	242	Shared Neighborhood Hits	33
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

IL12B_MOUSE
NC score	0.019401 (rank : 906)	θ value	4.03905 (rank : 471)
Query Neighborhood Hits	557	Target Neighborhood Hits	43	Shared Neighborhood Hits	8
SwissProt Accessions	P43432, Q9QUM1	Gene names	Il12b
Domain Architecture
Description	Interleukin-12 beta chain precursor (IL-12B) (IL-12 p40) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40).

I12R1_HUMAN
NC score	0.018801 (rank : 907)	θ value	4.03905 (rank : 470)
Query Neighborhood Hits	557	Target Neighborhood Hits	78	Shared Neighborhood Hits	25
SwissProt Accessions	P42701	Gene names	IL12RB1, IL12R, IL12RB
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (IL- 12RB1) (CD212 antigen).

BTBDC_HUMAN
NC score	0.018591 (rank : 908)	θ value	5.27518 (rank : 486)
Query Neighborhood Hits	557	Target Neighborhood Hits	248	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

EPN3_MOUSE
NC score	0.018222 (rank : 909)	θ value	3.0926 (rank : 443)
Query Neighborhood Hits	557	Target Neighborhood Hits	312	Shared Neighborhood Hits	44
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

HRBL_MOUSE
NC score	0.018070 (rank : 910)	θ value	1.06291 (rank : 370)
Query Neighborhood Hits	557	Target Neighborhood Hits	269	Shared Neighborhood Hits	28
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

TCF19_HUMAN
NC score	0.017601 (rank : 911)	θ value	5.27518 (rank : 499)
Query Neighborhood Hits	557	Target Neighborhood Hits	124	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y242, Q13176, Q15967, Q5SQ89, Q5STD6, Q5STF5, Q9BUM2, Q9UBH7	Gene names	TCF19, SC1
Domain Architecture
Description	Transcription factor 19 (Transcription factor SC1).

EPN3_HUMAN
NC score	0.017590 (rank : 912)	θ value	8.99809 (rank : 544)
Query Neighborhood Hits	557	Target Neighborhood Hits	197	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

MYO15_HUMAN
NC score	0.017554 (rank : 913)	θ value	0.0736092 (rank : 266)
Query Neighborhood Hits	557	Target Neighborhood Hits	671	Shared Neighborhood Hits	92
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

DAB2_HUMAN
NC score	0.016358 (rank : 914)	θ value	1.81305 (rank : 400)
Query Neighborhood Hits	557	Target Neighborhood Hits	197	Shared Neighborhood Hits	29
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

K1333_HUMAN
NC score	0.016141 (rank : 915)	θ value	1.06291 (rank : 372)
Query Neighborhood Hits	557	Target Neighborhood Hits	50	Shared Neighborhood Hits	9
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

K1219_HUMAN
NC score	0.015975 (rank : 916)	θ value	6.88961 (rank : 522)
Query Neighborhood Hits	557	Target Neighborhood Hits	85	Shared Neighborhood Hits	17
SwissProt Accessions	Q86X10, Q5TG31, Q8N3D1, Q8WWC0, Q9H3X8, Q9UJR1, Q9ULK1, Q9Y3G9	Gene names	KIAA1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

RFIP3_HUMAN
NC score	0.015682 (rank : 917)	θ value	1.38821 (rank : 388)
Query Neighborhood Hits	557	Target Neighborhood Hits	1055	Shared Neighborhood Hits	48
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

DACT1_HUMAN
NC score	0.015533 (rank : 918)	θ value	8.99809 (rank : 542)
Query Neighborhood Hits	557	Target Neighborhood Hits	228	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NYF0, Q86TY0	Gene names	DACT1, DPR1, HNG3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene 3 protein).

ZFHX2_HUMAN
NC score	0.014848 (rank : 919)	θ value	0.279714 (rank : 322)
Query Neighborhood Hits	557	Target Neighborhood Hits	1178	Shared Neighborhood Hits	74
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

SMAL1_MOUSE
NC score	0.014587 (rank : 920)	θ value	0.0961366 (rank : 281)
Query Neighborhood Hits	557	Target Neighborhood Hits	157	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

MRCKB_MOUSE
NC score	0.014569 (rank : 921)	θ value	8.99809 (rank : 551)
Query Neighborhood Hits	557	Target Neighborhood Hits	2180	Shared Neighborhood Hits	88
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

NIPA_MOUSE
NC score	0.014520 (rank : 922)	θ value	3.0926 (rank : 454)
Query Neighborhood Hits	557	Target Neighborhood Hits	50	Shared Neighborhood Hits	11
SwissProt Accessions	Q80YV2, Q3TJE6, Q80Z11, Q8BTW5, Q8CI56, Q8R3U7	Gene names	Zc3hc1, Nipa
Domain Architecture	No domain graphic available
Description	Nuclear-interacting partner of ALK (Nuclear-interacting partner of anaplastic lymphoma kinase) (mNIPA) (Zinc finger C3HC-type protein 1).

K1219_MOUSE
NC score	0.014129 (rank : 923)	θ value	3.0926 (rank : 449)
Query Neighborhood Hits	557	Target Neighborhood Hits	67	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BQZ4, Q80TH5, Q8BQN1	Gene names	Kiaa1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

SOX13_HUMAN
NC score	0.014053 (rank : 924)	θ value	4.03905 (rank : 481)
Query Neighborhood Hits	557	Target Neighborhood Hits	464	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

WNK1_HUMAN
NC score	0.013975 (rank : 925)	θ value	0.813845 (rank : 365)
Query Neighborhood Hits	557	Target Neighborhood Hits	1158	Shared Neighborhood Hits	114
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

ZN385_HUMAN
NC score	0.013883 (rank : 926)	θ value	6.88961 (rank : 536)
Query Neighborhood Hits	557	Target Neighborhood Hits	614	Shared Neighborhood Hits	41
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

P73L_HUMAN
NC score	0.013873 (rank : 927)	θ value	0.62314 (rank : 354)
Query Neighborhood Hits	557	Target Neighborhood Hits	102	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H3D4, O75080, O75195, O75922, O76078, Q6VEG2, Q6VEG3, Q6VEG4, Q6VFJ1, Q6VFJ2, Q6VFJ3, Q6VH20, Q7LDI3, Q7LDI4, Q7LDI5, Q96KR0, Q9H3D2, Q9H3D3, Q9H3P8, Q9NPH7, Q9P1B4, Q9P1B5, Q9P1B6, Q9P1B7, Q9UBV9, Q9UE10, Q9UP26, Q9UP27, Q9UP28, Q9UP74	Gene names	TP73L, KET, P63, P73H, P73L
Domain Architecture	No domain graphic available
Description	Tumor protein p73-like (p73L) (p63) (Tumor protein 63) (TP63) (p51) (p40) (Keratinocyte transcription factor KET) (Chronic ulcerative stomatitis protein) (CUSP).

NUPL_HUMAN
NC score	0.013695 (rank : 928)	θ value	1.81305 (rank : 408)
Query Neighborhood Hits	557	Target Neighborhood Hits	68	Shared Neighborhood Hits	7
SwissProt Accessions	P52594, Q15277, Q4VAS0, Q4VAS1, Q4VAS3, Q53QT8, Q53R11	Gene names	HRB, RAB, RIP
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein) (Rev- interacting protein) (Rev/Rex activation domain-binding protein).

BASI_MOUSE
NC score	0.013431 (rank : 929)	θ value	8.99809 (rank : 541)
Query Neighborhood Hits	557	Target Neighborhood Hits	238	Shared Neighborhood Hits	15
SwissProt Accessions	P18572, Q6LDB0, Q7TSC0	Gene names	Bsg
Domain Architecture
Description	Basigin precursor (Basic immunoglobulin superfamily) (Membrane glycoprotein gp42) (HT7 antigen) (CD147 antigen).

MAGL2_HUMAN
NC score	0.013157 (rank : 930)	θ value	1.06291 (rank : 373)
Query Neighborhood Hits	557	Target Neighborhood Hits	69	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UJ55	Gene names	MAGEL2, NDNL1
Domain Architecture
Description	MAGE-like protein 2 (Necdin-like protein 1) (Protein nM15).

JIP3_HUMAN
NC score	0.012800 (rank : 931)	θ value	3.0926 (rank : 448)
Query Neighborhood Hits	557	Target Neighborhood Hits	1039	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

CD45_HUMAN
NC score	0.012198 (rank : 932)	θ value	5.27518 (rank : 488)
Query Neighborhood Hits	557	Target Neighborhood Hits	243	Shared Neighborhood Hits	36
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

PAPOG_HUMAN
NC score	0.011157 (rank : 933)	θ value	1.38821 (rank : 387)
Query Neighborhood Hits	557	Target Neighborhood Hits	44	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BWT3, Q969N1, Q9H8L2, Q9HAD0	Gene names	PAPOLG, PAP2, PAPG
Domain Architecture
Description	Poly(A) polymerase gamma (EC 2.7.7.19) (PAP gamma) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3' adenylating enzyme) (Neo- poly(A) polymerase) (Neo-PAP).

FHOD1_HUMAN
NC score	0.011045 (rank : 934)	θ value	6.88961 (rank : 516)
Query Neighborhood Hits	557	Target Neighborhood Hits	184	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

P2RX2_HUMAN
NC score	0.010877 (rank : 935)	θ value	2.36792 (rank : 429)
Query Neighborhood Hits	557	Target Neighborhood Hits	110	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UBL9, Q6V9R6, Q9NR37, Q9NR38, Q9UHD5, Q9UHD6, Q9UHD7, Q9Y637, Q9Y638	Gene names	P2RX2, P2X2
Domain Architecture
Description	P2X purinoceptor 2 (ATP receptor) (P2X2) (Purinergic receptor).

ELK4_HUMAN
NC score	0.010875 (rank : 936)	θ value	0.62314 (rank : 350)
Query Neighborhood Hits	557	Target Neighborhood Hits	184	Shared Neighborhood Hits	27
SwissProt Accessions	P28324, P28323	Gene names	ELK4, SAP1
Domain Architecture
Description	ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1).

USH1C_MOUSE
NC score	0.010874 (rank : 937)	θ value	3.0926 (rank : 460)
Query Neighborhood Hits	557	Target Neighborhood Hits	557	Shared Neighborhood Hits	34
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

SCNNG_HUMAN
NC score	0.010832 (rank : 938)	θ value	0.813845 (rank : 363)
Query Neighborhood Hits	557	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P51170, P78437, Q6PCC2, Q93023, Q93024, Q93025, Q93026, Q93027, Q96TD2	Gene names	SCNN1G
Domain Architecture
Description	Amiloride-sensitive sodium channel gamma-subunit (Epithelial Na+ channel subunit gamma) (Gamma ENaC) (Nonvoltage-gated sodium channel 1 subunit gamma) (SCNEG) (Gamma NaCH).

DGKB_HUMAN
NC score	0.010724 (rank : 939)	θ value	0.813845 (rank : 358)
Query Neighborhood Hits	557	Target Neighborhood Hits	238	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y6T7, O75241, Q75MF9, Q75MU7, Q86UI5, Q86UM9, Q9UQ29	Gene names	DGKB, DAGK2, KIAA0718
Domain Architecture
Description	Diacylglycerol kinase beta (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta) (DAG kinase beta) (90 kDa diacylglycerol kinase).

AKAP1_MOUSE
NC score	0.009956 (rank : 940)	θ value	8.99809 (rank : 540)
Query Neighborhood Hits	557	Target Neighborhood Hits	198	Shared Neighborhood Hits	26
SwissProt Accessions	O08715, O08714, P97488	Gene names	Akap1, Akap
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein) (S-AKAP).

EVI2A_MOUSE
NC score	0.009812 (rank : 941)	θ value	6.88961 (rank : 515)
Query Neighborhood Hits	557	Target Neighborhood Hits	34	Shared Neighborhood Hits	6
SwissProt Accessions	P20934	Gene names	Evi2a, Evi-2, Evi-2a, Evi2
Domain Architecture
Description	EVI2A protein precursor (Ecotropic viral integration site 2A protein).

ZNF45_HUMAN
NC score	0.009409 (rank : 942)	θ value	0.0113563 (rank : 207)
Query Neighborhood Hits	557	Target Neighborhood Hits	773	Shared Neighborhood Hits	52
SwissProt Accessions	Q02386, P78472, Q9P1U9	Gene names	ZNF45
Domain Architecture
Description	Zinc finger protein 45 (BRC1744).

PAPOG_MOUSE
NC score	0.009264 (rank : 943)	θ value	6.88961 (rank : 527)
Query Neighborhood Hits	557	Target Neighborhood Hits	103	Shared Neighborhood Hits	17
SwissProt Accessions	Q6PCL9, Q8BZC9	Gene names	Papolg
Domain Architecture	No domain graphic available
Description	Poly(A) polymerase gamma (EC 2.7.7.19) (PAP gamma) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3' adenylating enzyme).

GAK4_HUMAN
NC score	0.008988 (rank : 944)	θ value	6.88961 (rank : 519)
Query Neighborhood Hits	557	Target Neighborhood Hits	415	Shared Neighborhood Hits	42
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GCP6_HUMAN
NC score	0.008954 (rank : 945)	θ value	3.0926 (rank : 445)
Query Neighborhood Hits	557	Target Neighborhood Hits	295	Shared Neighborhood Hits	13
SwissProt Accessions	Q96RT7, Q5JZ80, Q6PJ40, Q86YE9, Q9BY91, Q9UGX3, Q9UGX4	Gene names	TUBGCP6, GCP6, KIAA1669
Domain Architecture
Description	Gamma-tubulin complex component 6 (GCP-6).

RIPK3_MOUSE
NC score	0.008929 (rank : 946)	θ value	6.88961 (rank : 530)
Query Neighborhood Hits	557	Target Neighborhood Hits	867	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QZL0	Gene names	Ripk3, Rip3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3).

ITSN1_HUMAN
NC score	0.008850 (rank : 947)	θ value	8.99809 (rank : 548)
Query Neighborhood Hits	557	Target Neighborhood Hits	1757	Shared Neighborhood Hits	65
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

SCNNB_HUMAN
NC score	0.008847 (rank : 948)	θ value	2.36792 (rank : 431)
Query Neighborhood Hits	557	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	P51168, O60891, Q96KG2, Q9UJ32, Q9UMU5	Gene names	SCNN1B
Domain Architecture
Description	Amiloride-sensitive sodium channel subunit beta (Epithelial Na+ channel subunit beta) (Beta ENaC) (Nonvoltage-gated sodium channel 1 subunit beta) (SCNEB) (Beta NaCH) (ENaCB).

GAK11_HUMAN
NC score	0.008839 (rank : 949)	θ value	6.88961 (rank : 517)
Query Neighborhood Hits	557	Target Neighborhood Hits	409	Shared Neighborhood Hits	42
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
NC score	0.008705 (rank : 950)	θ value	6.88961 (rank : 518)
Query Neighborhood Hits	557	Target Neighborhood Hits	406	Shared Neighborhood Hits	41
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

VP13B_HUMAN
NC score	0.008590 (rank : 951)	θ value	5.27518 (rank : 504)
Query Neighborhood Hits	557	Target Neighborhood Hits	78	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z7G8, Q709C6, Q709C7, Q7Z7G4, Q7Z7G5, Q7Z7G6, Q7Z7G7, Q8NB77, Q9NWV1, Q9Y4E7	Gene names	VPS13B, CHS1, COH1, KIAA0532
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1).

ZN221_HUMAN
NC score	0.008360 (rank : 952)	θ value	0.813845 (rank : 366)
Query Neighborhood Hits	557	Target Neighborhood Hits	784	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UK13, Q9P1U8	Gene names	ZNF221
Domain Architecture
Description	Zinc finger protein 221.

GAK6_HUMAN
NC score	0.008148 (rank : 953)	θ value	8.99809 (rank : 546)
Query Neighborhood Hits	557	Target Neighborhood Hits	392	Shared Neighborhood Hits	41
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

DUET_HUMAN
NC score	0.008127 (rank : 954)	θ value	1.81305 (rank : 401)
Query Neighborhood Hits	557	Target Neighborhood Hits	1220	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

HDAC6_MOUSE
NC score	0.007981 (rank : 955)	θ value	2.36792 (rank : 427)
Query Neighborhood Hits	557	Target Neighborhood Hits	88	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z2V5	Gene names	Hdac6
Domain Architecture
Description	Histone deacetylase 6 (HD6) (Histone deacetylase mHDA2).

UBQL3_MOUSE
NC score	0.006905 (rank : 956)	θ value	8.99809 (rank : 557)
Query Neighborhood Hits	557	Target Neighborhood Hits	120	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C5U9	Gene names	Ubqln3
Domain Architecture
Description	Ubiquilin-3.

CAMKV_HUMAN
NC score	0.006724 (rank : 957)	θ value	1.81305 (rank : 399)
Query Neighborhood Hits	557	Target Neighborhood Hits	1084	Shared Neighborhood Hits	77
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

TTLL5_MOUSE
NC score	0.006060 (rank : 958)	θ value	5.27518 (rank : 503)
Query Neighborhood Hits	557	Target Neighborhood Hits	150	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CHB8	Gene names	Ttll5, Kiaa0998
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5.

ZN155_HUMAN
NC score	0.006011 (rank : 959)	θ value	0.0736092 (rank : 272)
Query Neighborhood Hits	557	Target Neighborhood Hits	786	Shared Neighborhood Hits	54
SwissProt Accessions	Q12901, Q9UIE1, Q9UK14	Gene names	ZNF155
Domain Architecture
Description	Zinc finger protein 155.

CDC27_HUMAN
NC score	0.005660 (rank : 960)	θ value	6.88961 (rank : 510)
Query Neighborhood Hits	557	Target Neighborhood Hits	139	Shared Neighborhood Hits	12
SwissProt Accessions	P30260, Q16349, Q96F35	Gene names	CDC27
Domain Architecture
Description	Cell division cycle protein 27 homolog (CDC27Hs) (H-NUC).

PAK4_MOUSE
NC score	0.005627 (rank : 961)	θ value	6.88961 (rank : 526)
Query Neighborhood Hits	557	Target Neighborhood Hits	1098	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

PKP4_HUMAN
NC score	0.005518 (rank : 962)	θ value	4.03905 (rank : 475)
Query Neighborhood Hits	557	Target Neighborhood Hits	107	Shared Neighborhood Hits	15
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

EDD1_HUMAN
NC score	0.004702 (rank : 963)	θ value	4.03905 (rank : 467)
Query Neighborhood Hits	557	Target Neighborhood Hits	170	Shared Neighborhood Hits	12
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

LHX2_MOUSE
NC score	0.004530 (rank : 964)	θ value	6.88961 (rank : 524)
Query Neighborhood Hits	557	Target Neighborhood Hits	431	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z0S2	Gene names	Lhx2
Domain Architecture
Description	LIM/homeobox protein Lhx2.

LHX2_HUMAN
NC score	0.004523 (rank : 965)	θ value	6.88961 (rank : 523)
Query Neighborhood Hits	557	Target Neighborhood Hits	432	Shared Neighborhood Hits	19
SwissProt Accessions	P50458, O95860, Q8N1Z3	Gene names	LHX2, LH2
Domain Architecture
Description	LIM/homeobox protein Lhx2 (Homeobox protein LH-2).

JHD2B_HUMAN
NC score	0.004132 (rank : 966)	θ value	8.99809 (rank : 549)
Query Neighborhood Hits	557	Target Neighborhood Hits	171	Shared Neighborhood Hits	21
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

ZEP1_HUMAN
NC score	0.003994 (rank : 967)	θ value	5.27518 (rank : 505)
Query Neighborhood Hits	557	Target Neighborhood Hits	1036	Shared Neighborhood Hits	70
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

SMAD4_MOUSE
NC score	0.003880 (rank : 968)	θ value	6.88961 (rank : 532)
Query Neighborhood Hits	557	Target Neighborhood Hits	101	Shared Neighborhood Hits	15
SwissProt Accessions	P97471, Q9CW56	Gene names	Smad4, Dpc4, Madh4
Domain Architecture
Description	Mothers against decapentaplegic homolog 4 (SMAD 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4 homolog) (Smad4).

FOXN1_HUMAN
NC score	0.003500 (rank : 969)	θ value	5.27518 (rank : 493)
Query Neighborhood Hits	557	Target Neighborhood Hits	377	Shared Neighborhood Hits	27
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

FOXH1_HUMAN
NC score	0.003485 (rank : 970)	θ value	5.27518 (rank : 492)
Query Neighborhood Hits	557	Target Neighborhood Hits	258	Shared Neighborhood Hits	24
SwissProt Accessions	O75593	Gene names	FOXH1, FAST1, FAST2
Domain Architecture
Description	Forkhead box protein H1 (Forkhead activin signal transducer 1) (Fast- 1) (hFAST-1) (Forkhead activin signal transducer 2) (Fast-2).

TRAF3_MOUSE
NC score	0.003133 (rank : 971)	θ value	5.27518 (rank : 502)
Query Neighborhood Hits	557	Target Neighborhood Hits	476	Shared Neighborhood Hits	12
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

SEM6B_HUMAN
NC score	0.002736 (rank : 972)	θ value	6.88961 (rank : 531)
Query Neighborhood Hits	557	Target Neighborhood Hits	187	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

SOX15_HUMAN
NC score	0.001895 (rank : 973)	θ value	4.03905 (rank : 482)
Query Neighborhood Hits	557	Target Neighborhood Hits	134	Shared Neighborhood Hits	5
SwissProt Accessions	O60248, P35717, Q9Y6W7	Gene names	SOX15, SOX12, SOX20, SOX26, SOX27
Domain Architecture
Description	SOX-15 protein (SOX-20 protein) (SOX-12 protein).

ZN234_HUMAN
NC score	0.001544 (rank : 974)	θ value	1.06291 (rank : 380)
Query Neighborhood Hits	557	Target Neighborhood Hits	785	Shared Neighborhood Hits	47
SwissProt Accessions	Q14588, Q96IR4, Q9NS45, Q9NYT7	Gene names	ZNF234, ZNF269
Domain Architecture	No domain graphic available
Description	Zinc finger protein 234 (Zinc finger protein HZF4).

ZN230_HUMAN
NC score	0.001318 (rank : 975)	θ value	0.279714 (rank : 323)
Query Neighborhood Hits	557	Target Neighborhood Hits	750	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UIE0, O15322, Q9P1U6	Gene names	ZNF230, FDZF2
Domain Architecture
Description	Zinc finger protein 230 (Zinc finger protein FDZF2).

KCNB2_HUMAN
NC score	-0.000474 (rank : 976)	θ value	3.0926 (rank : 450)
Query Neighborhood Hits	557	Target Neighborhood Hits	212	Shared Neighborhood Hits	11
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

TCF17_HUMAN
NC score	-0.000776 (rank : 977)	θ value	4.03905 (rank : 483)
Query Neighborhood Hits	557	Target Neighborhood Hits	797	Shared Neighborhood Hits	47
SwissProt Accessions	O60765, Q9UNJ8	Gene names	ZNF354A, EZNF, HKL1, TCF17
Domain Architecture
Description	Zinc finger protein 354A (Transcription factor 17) (Zinc finger protein eZNF).

ZN467_MOUSE
NC score	-0.000794 (rank : 978)	θ value	3.0926 (rank : 461)
Query Neighborhood Hits	557	Target Neighborhood Hits	794	Shared Neighborhood Hits	45
SwissProt Accessions	Q8JZL0, Q9JJ98	Gene names	Znf467, Ezi, Zfp467
Domain Architecture	No domain graphic available
Description	Zinc finger protein 467 (Endothelial cell-derived zinc finger protein) (EZI).

ZN217_HUMAN
NC score	-0.001865 (rank : 979)	θ value	6.88961 (rank : 535)
Query Neighborhood Hits	557	Target Neighborhood Hits	905	Shared Neighborhood Hits	57
SwissProt Accessions	O75362	Gene names	ZNF217, ZABC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 217.

ZNF77_HUMAN
NC score	-0.002458 (rank : 980)	θ value	6.88961 (rank : 537)
Query Neighborhood Hits	557	Target Neighborhood Hits	759	Shared Neighborhood Hits	40
SwissProt Accessions	Q15935, Q86XJ3, Q9NPP0	Gene names	ZNF77
Domain Architecture	No domain graphic available
Description	Zinc finger protein 77 (ZNFpT1).

ZN711_HUMAN
NC score	-0.002579 (rank : 981)	θ value	0.813845 (rank : 367)
Query Neighborhood Hits	557	Target Neighborhood Hits	751	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y462, Q6NX42, Q9Y4J6	Gene names	ZNF711, CMPX1, ZNF6
Domain Architecture
Description	Zinc finger protein 711 (Zinc finger protein 6).

ZN699_HUMAN
NC score	-0.003091 (rank : 982)	θ value	1.38821 (rank : 395)
Query Neighborhood Hits	557	Target Neighborhood Hits	773	Shared Neighborhood Hits	39
SwissProt Accessions	Q32M78, Q8N9A1	Gene names	ZNF699
Domain Architecture	No domain graphic available
Description	Zinc finger protein 699 (Hangover homolog).

PAX6_HUMAN
NC score	-0.003093 (rank : 983)	θ value	3.0926 (rank : 455)
Query Neighborhood Hits	557	Target Neighborhood Hits	383	Shared Neighborhood Hits	9
SwissProt Accessions	P26367, Q6N006, Q99413	Gene names	PAX6, AN2
Domain Architecture
Description	Paired box protein Pax-6 (Oculorhombin) (Aniridia type II protein).

PAX6_MOUSE
NC score	-0.003093 (rank : 984)	θ value	3.0926 (rank : 456)
Query Neighborhood Hits	557	Target Neighborhood Hits	383	Shared Neighborhood Hits	9
SwissProt Accessions	P63015, P32117, P70601, Q62222, Q64037, Q8CEI5, Q8VDB5, Q921Q8	Gene names	Pax6, Pax-6, Sey
Domain Architecture	No domain graphic available
Description	Paired box protein Pax-6 (Oculorhombin).

ZFX_MOUSE
NC score	-0.003133 (rank : 985)	θ value	2.36792 (rank : 437)
Query Neighborhood Hits	557	Target Neighborhood Hits	748	Shared Neighborhood Hits	27
SwissProt Accessions	P17012, P17011	Gene names	Zfx
Domain Architecture
Description	Zinc finger X-chromosomal protein.

ZFX_HUMAN
NC score	-0.003173 (rank : 986)	θ value	2.36792 (rank : 436)
Query Neighborhood Hits	557	Target Neighborhood Hits	751	Shared Neighborhood Hits	27
SwissProt Accessions	P17010, O43668, Q8WYJ8	Gene names	ZFX
Domain Architecture
Description	Zinc finger X-chromosomal protein.

ZFY_HUMAN
NC score	-0.003199 (rank : 987)	θ value	5.27518 (rank : 506)
Query Neighborhood Hits	557	Target Neighborhood Hits	752	Shared Neighborhood Hits	28
SwissProt Accessions	P08048, Q14021, Q15558, Q96TF3	Gene names	ZFY
Domain Architecture
Description	Zinc finger Y-chromosomal protein.

ZNF93_HUMAN
NC score	-0.004193 (rank : 988)	θ value	3.0926 (rank : 462)
Query Neighborhood Hits	557	Target Neighborhood Hits	776	Shared Neighborhood Hits	37
SwissProt Accessions	P35789, Q8N8Q4, Q9H9X5, Q9Y2N8	Gene names	ZNF93, ZNF505
Domain Architecture	No domain graphic available
Description	Zinc finger protein 93 (Zinc finger protein 505) (Zinc finger protein HTF34).

HKR3_HUMAN
NC score	-0.005308 (rank : 989)	θ value	5.27518 (rank : 494)
Query Neighborhood Hits	557	Target Neighborhood Hits	839	Shared Neighborhood Hits	34
SwissProt Accessions	P10074	Gene names	HKR3
Domain Architecture
Description	Krueppel-related zinc finger protein 3 (Protein HKR3).

KAISO_HUMAN
NC score	-0.005388 (rank : 990)	θ value	8.99809 (rank : 550)
Query Neighborhood Hits	557	Target Neighborhood Hits	840	Shared Neighborhood Hits	44
SwissProt Accessions	Q86T24, O00319, Q7Z361, Q8IVP6, Q8N3P0	Gene names	ZBTB33, KAISO, ZNF348
Domain Architecture	No domain graphic available
Description	Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33).

KLF10_HUMAN
NC score	-0.006289 (rank : 991)	θ value	5.27518 (rank : 495)
Query Neighborhood Hits	557	Target Neighborhood Hits	744	Shared Neighborhood Hits	36
SwissProt Accessions	Q13118	Gene names	KLF10, TIEG, TIEG1
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 10 (Transforming growth factor-beta-inducible early growth response protein 1) (TGFB-inducible early growth response protein 1) (TIEG-1) (EGR-alpha).

MTR1L_HUMAN
NC score	-0.007646 (rank : 992)	θ value	0.62314 (rank : 353)
Query Neighborhood Hits	557	Target Neighborhood Hits	1180	Shared Neighborhood Hits	44
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).