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Network neighborhood for query Sequence : BAI3_HUMAN

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BAI3_HUMAN
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

BAI1_HUMAN
θ value	0 (rank : 1)	NC score	0.980568 (rank : 6)
Query Neighborhood Hits	246	Target Neighborhood Hits	375	Shared Neighborhood Hits	182
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_MOUSE
θ value	0 (rank : 2)	NC score	0.982875 (rank : 5)
Query Neighborhood Hits	246	Target Neighborhood Hits	340	Shared Neighborhood Hits	178
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI2_HUMAN
θ value	0 (rank : 3)	NC score	0.984256 (rank : 4)
Query Neighborhood Hits	246	Target Neighborhood Hits	332	Shared Neighborhood Hits	185
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_MOUSE
θ value	0 (rank : 4)	NC score	0.984776 (rank : 3)
Query Neighborhood Hits	246	Target Neighborhood Hits	323	Shared Neighborhood Hits	185
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI3_HUMAN
θ value	0 (rank : 5)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	246	Target Neighborhood Hits	246	Shared Neighborhood Hits	246
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
θ value	0 (rank : 6)	NC score	0.999189 (rank : 2)
Query Neighborhood Hits	246	Target Neighborhood Hits	250	Shared Neighborhood Hits	230
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

HMCN1_HUMAN
θ value	5.73848e-55 (rank : 7)	NC score	0.352271 (rank : 126)
Query Neighborhood Hits	246	Target Neighborhood Hits	983	Shared Neighborhood Hits	132
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

PROP_MOUSE
θ value	7.25919e-50 (rank : 8)	NC score	0.725544 (rank : 7)
Query Neighborhood Hits	246	Target Neighborhood Hits	165	Shared Neighborhood Hits	90
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

CELR2_MOUSE
θ value	1.32601e-43 (rank : 9)	NC score	0.353358 (rank : 124)
Query Neighborhood Hits	246	Target Neighborhood Hits	584	Shared Neighborhood Hits	109
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

CELR2_HUMAN
θ value	2.95404e-43 (rank : 10)	NC score	0.346742 (rank : 128)
Query Neighborhood Hits	246	Target Neighborhood Hits	657	Shared Neighborhood Hits	119
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CELR1_HUMAN
θ value	5.03882e-43 (rank : 11)	NC score	0.356347 (rank : 121)
Query Neighborhood Hits	246	Target Neighborhood Hits	613	Shared Neighborhood Hits	107
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CELR1_MOUSE
θ value	8.59492e-43 (rank : 12)	NC score	0.352273 (rank : 125)
Query Neighborhood Hits	246	Target Neighborhood Hits	617	Shared Neighborhood Hits	114
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

LPHN1_HUMAN
θ value	5.57106e-42 (rank : 13)	NC score	0.632684 (rank : 19)
Query Neighborhood Hits	246	Target Neighborhood Hits	155	Shared Neighborhood Hits	80
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

LPHN3_HUMAN
θ value	1.79215e-40 (rank : 14)	NC score	0.632339 (rank : 20)
Query Neighborhood Hits	246	Target Neighborhood Hits	139	Shared Neighborhood Hits	88
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

PROP_HUMAN
θ value	2.58786e-39 (rank : 15)	NC score	0.715297 (rank : 8)
Query Neighborhood Hits	246	Target Neighborhood Hits	126	Shared Neighborhood Hits	87
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

TSP2_HUMAN
θ value	6.37413e-38 (rank : 16)	NC score	0.542360 (rank : 40)
Query Neighborhood Hits	246	Target Neighborhood Hits	359	Shared Neighborhood Hits	122
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP2_MOUSE
θ value	6.37413e-38 (rank : 17)	NC score	0.542013 (rank : 41)
Query Neighborhood Hits	246	Target Neighborhood Hits	352	Shared Neighborhood Hits	120
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

EMR4_MOUSE
θ value	2.05049e-36 (rank : 18)	NC score	0.685867 (rank : 10)
Query Neighborhood Hits	246	Target Neighborhood Hits	191	Shared Neighborhood Hits	85
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

GP133_HUMAN
θ value	3.4976e-36 (rank : 19)	NC score	0.694296 (rank : 9)
Query Neighborhood Hits	246	Target Neighborhood Hits	115	Shared Neighborhood Hits	88
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

TSP1_MOUSE
θ value	4.568e-36 (rank : 20)	NC score	0.533743 (rank : 44)
Query Neighborhood Hits	246	Target Neighborhood Hits	396	Shared Neighborhood Hits	119
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

LPHN2_HUMAN
θ value	2.26708e-35 (rank : 21)	NC score	0.625623 (rank : 22)
Query Neighborhood Hits	246	Target Neighborhood Hits	136	Shared Neighborhood Hits	83
SwissProt Accessions	O95490, O94882, Q5VX76, Q9UKY5, Q9UKY6	Gene names	LPHN2, KIAA0786, LEC1, LPHH1
Domain Architecture
Description	Latrophilin-2 precursor (Calcium-independent alpha-latrotoxin receptor 2) (Latrophilin homolog 1) (Lectomedin-1).

TSP1_HUMAN
θ value	3.86705e-35 (rank : 22)	NC score	0.530353 (rank : 45)
Query Neighborhood Hits	246	Target Neighborhood Hits	389	Shared Neighborhood Hits	121
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

EMR1_MOUSE
θ value	5.0505e-35 (rank : 23)	NC score	0.510384 (rank : 51)
Query Neighborhood Hits	246	Target Neighborhood Hits	349	Shared Neighborhood Hits	104
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

CELR3_MOUSE
θ value	5.584e-34 (rank : 24)	NC score	0.324319 (rank : 141)
Query Neighborhood Hits	246	Target Neighborhood Hits	687	Shared Neighborhood Hits	122
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

CELR3_HUMAN
θ value	7.29293e-34 (rank : 25)	NC score	0.324511 (rank : 140)
Query Neighborhood Hits	246	Target Neighborhood Hits	680	Shared Neighborhood Hits	117
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

ELTD1_MOUSE
θ value	1.16434e-31 (rank : 26)	NC score	0.579362 (rank : 35)
Query Neighborhood Hits	246	Target Neighborhood Hits	288	Shared Neighborhood Hits	98
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

SEM5B_HUMAN
θ value	4.42448e-31 (rank : 27)	NC score	0.458326 (rank : 76)
Query Neighborhood Hits	246	Target Neighborhood Hits	178	Shared Neighborhood Hits	87
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

ELTD1_HUMAN
θ value	1.28732e-30 (rank : 28)	NC score	0.650686 (rank : 15)
Query Neighborhood Hits	246	Target Neighborhood Hits	269	Shared Neighborhood Hits	98
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

CD97_HUMAN
θ value	4.89182e-30 (rank : 29)	NC score	0.513419 (rank : 50)
Query Neighborhood Hits	246	Target Neighborhood Hits	353	Shared Neighborhood Hits	103
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

SEM5B_MOUSE
θ value	1.08979e-29 (rank : 30)	NC score	0.460434 (rank : 72)
Query Neighborhood Hits	246	Target Neighborhood Hits	190	Shared Neighborhood Hits	91
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

SEM5A_HUMAN
θ value	9.2256e-29 (rank : 31)	NC score	0.459086 (rank : 73)
Query Neighborhood Hits	246	Target Neighborhood Hits	177	Shared Neighborhood Hits	90
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEM5A_MOUSE
θ value	4.57862e-28 (rank : 32)	NC score	0.453708 (rank : 80)
Query Neighborhood Hits	246	Target Neighborhood Hits	162	Shared Neighborhood Hits	87
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SPON1_MOUSE
θ value	3.87602e-27 (rank : 33)	NC score	0.638625 (rank : 17)
Query Neighborhood Hits	246	Target Neighborhood Hits	123	Shared Neighborhood Hits	97
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

EMR3_HUMAN
θ value	1.12775e-26 (rank : 34)	NC score	0.646064 (rank : 16)
Query Neighborhood Hits	246	Target Neighborhood Hits	245	Shared Neighborhood Hits	88
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

SPON1_HUMAN
θ value	3.28125e-26 (rank : 35)	NC score	0.637714 (rank : 18)
Query Neighborhood Hits	246	Target Neighborhood Hits	117	Shared Neighborhood Hits	93
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

SSPO_MOUSE
θ value	3.62785e-25 (rank : 36)	NC score	0.430490 (rank : 98)
Query Neighborhood Hits	246	Target Neighborhood Hits	800	Shared Neighborhood Hits	132
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

EMR1_HUMAN
θ value	1.05554e-24 (rank : 37)	NC score	0.484165 (rank : 56)
Query Neighborhood Hits	246	Target Neighborhood Hits	382	Shared Neighborhood Hits	107
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EMR2_HUMAN
θ value	1.99067e-23 (rank : 38)	NC score	0.494638 (rank : 54)
Query Neighborhood Hits	246	Target Neighborhood Hits	345	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

GPR64_MOUSE
θ value	2.59989e-23 (rank : 39)	NC score	0.653557 (rank : 13)
Query Neighborhood Hits	246	Target Neighborhood Hits	156	Shared Neighborhood Hits	85
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

UNC5A_MOUSE
θ value	2.59989e-23 (rank : 40)	NC score	0.545500 (rank : 39)
Query Neighborhood Hits	246	Target Neighborhood Hits	203	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

GP113_HUMAN
θ value	1.29031e-22 (rank : 41)	NC score	0.679235 (rank : 11)
Query Neighborhood Hits	246	Target Neighborhood Hits	102	Shared Neighborhood Hits	77
SwissProt Accessions	Q8IZF5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3	Gene names	GPR113, PGR23
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 113 precursor (G-protein coupled receptor PGR23).

UNC5B_HUMAN
θ value	2.87452e-22 (rank : 42)	NC score	0.539131 (rank : 43)
Query Neighborhood Hits	246	Target Neighborhood Hits	225	Shared Neighborhood Hits	78
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5B_MOUSE
θ value	2.87452e-22 (rank : 43)	NC score	0.541031 (rank : 42)
Query Neighborhood Hits	246	Target Neighborhood Hits	226	Shared Neighborhood Hits	78
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5C_MOUSE
θ value	2.87452e-22 (rank : 44)	NC score	0.527151 (rank : 47)
Query Neighborhood Hits	246	Target Neighborhood Hits	225	Shared Neighborhood Hits	77
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

UNC5C_HUMAN
θ value	3.75424e-22 (rank : 45)	NC score	0.527241 (rank : 46)
Query Neighborhood Hits	246	Target Neighborhood Hits	226	Shared Neighborhood Hits	77
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

GP112_HUMAN
θ value	4.9032e-22 (rank : 46)	NC score	0.597426 (rank : 31)
Query Neighborhood Hits	246	Target Neighborhood Hits	441	Shared Neighborhood Hits	84
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

GPR64_HUMAN
θ value	4.9032e-22 (rank : 47)	NC score	0.650931 (rank : 14)
Query Neighborhood Hits	246	Target Neighborhood Hits	207	Shared Neighborhood Hits	83
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

CD97_MOUSE
θ value	6.40375e-22 (rank : 48)	NC score	0.547733 (rank : 37)
Query Neighborhood Hits	246	Target Neighborhood Hits	295	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

GP128_HUMAN
θ value	7.0802e-21 (rank : 49)	NC score	0.659413 (rank : 12)
Query Neighborhood Hits	246	Target Neighborhood Hits	135	Shared Neighborhood Hits	76
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

UNC5D_MOUSE
θ value	1.2077e-20 (rank : 50)	NC score	0.503729 (rank : 53)
Query Neighborhood Hits	246	Target Neighborhood Hits	268	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

GP126_HUMAN
θ value	2.06002e-20 (rank : 51)	NC score	0.562552 (rank : 36)
Query Neighborhood Hits	246	Target Neighborhood Hits	187	Shared Neighborhood Hits	87
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

UNC5D_HUMAN
θ value	2.69047e-20 (rank : 52)	NC score	0.505480 (rank : 52)
Query Neighborhood Hits	246	Target Neighborhood Hits	267	Shared Neighborhood Hits	76
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

GP110_HUMAN
θ value	6.62687e-19 (rank : 53)	NC score	0.622996 (rank : 23)
Query Neighborhood Hits	246	Target Neighborhood Hits	87	Shared Neighborhood Hits	63
SwissProt Accessions	Q5T601, Q5KU15, Q5T5Z9, Q86SM1, Q8IXE3, Q8IZF8, Q96DQ1	Gene names	GPR110, PGR19
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 110 precursor (G-protein coupled receptor PGR19) (G-protein coupled receptor KPG_012).

GP110_MOUSE
θ value	8.65492e-19 (rank : 54)	NC score	0.614951 (rank : 27)
Query Neighborhood Hits	246	Target Neighborhood Hits	92	Shared Neighborhood Hits	62
SwissProt Accessions	Q8VEC3, Q8BMV8	Gene names	Gpr110
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 110 precursor.

GP116_HUMAN
θ value	3.28887e-18 (rank : 55)	NC score	0.620935 (rank : 26)
Query Neighborhood Hits	246	Target Neighborhood Hits	167	Shared Neighborhood Hits	67
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

ATS18_HUMAN
θ value	9.56915e-18 (rank : 56)	NC score	0.479642 (rank : 61)
Query Neighborhood Hits	246	Target Neighborhood Hits	169	Shared Neighborhood Hits	87
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS18_MOUSE
θ value	1.24977e-17 (rank : 57)	NC score	0.484627 (rank : 55)
Query Neighborhood Hits	246	Target Neighborhood Hits	163	Shared Neighborhood Hits	86
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS16_HUMAN
θ value	4.74913e-17 (rank : 58)	NC score	0.481377 (rank : 59)
Query Neighborhood Hits	246	Target Neighborhood Hits	208	Shared Neighborhood Hits	95
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

GP144_HUMAN
θ value	1.38178e-16 (rank : 59)	NC score	0.621434 (rank : 24)
Query Neighborhood Hits	246	Target Neighborhood Hits	108	Shared Neighborhood Hits	83
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

ATS17_HUMAN
θ value	2.35696e-16 (rank : 60)	NC score	0.478409 (rank : 62)
Query Neighborhood Hits	246	Target Neighborhood Hits	194	Shared Neighborhood Hits	90
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

ATS9_HUMAN
θ value	4.02038e-16 (rank : 61)	NC score	0.483505 (rank : 57)
Query Neighborhood Hits	246	Target Neighborhood Hits	219	Shared Neighborhood Hits	95
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

ATS2_MOUSE
θ value	1.16975e-15 (rank : 62)	NC score	0.467938 (rank : 66)
Query Neighborhood Hits	246	Target Neighborhood Hits	179	Shared Neighborhood Hits	78
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

GP115_HUMAN
θ value	1.99529e-15 (rank : 63)	NC score	0.597142 (rank : 32)
Query Neighborhood Hits	246	Target Neighborhood Hits	87	Shared Neighborhood Hits	63
SwissProt Accessions	Q8IZF3, Q5T5B5, Q5T5B6, Q86SN9, Q8IXE6	Gene names	GPR115, PGR18
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 (G-protein coupled receptor PGR18).

ATS19_HUMAN
θ value	2.60593e-15 (rank : 64)	NC score	0.450635 (rank : 86)
Query Neighborhood Hits	246	Target Neighborhood Hits	203	Shared Neighborhood Hits	79
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS19_MOUSE
θ value	3.40345e-15 (rank : 65)	NC score	0.458429 (rank : 74)
Query Neighborhood Hits	246	Target Neighborhood Hits	188	Shared Neighborhood Hits	80
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS20_HUMAN
θ value	3.40345e-15 (rank : 66)	NC score	0.465455 (rank : 67)
Query Neighborhood Hits	246	Target Neighborhood Hits	192	Shared Neighborhood Hits	92
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATL3_HUMAN
θ value	4.44505e-15 (rank : 67)	NC score	0.436112 (rank : 96)
Query Neighborhood Hits	246	Target Neighborhood Hits	414	Shared Neighborhood Hits	86
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

ATS16_MOUSE
θ value	7.58209e-15 (rank : 68)	NC score	0.481805 (rank : 58)
Query Neighborhood Hits	246	Target Neighborhood Hits	179	Shared Neighborhood Hits	94
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS20_MOUSE
θ value	7.58209e-15 (rank : 69)	NC score	0.474683 (rank : 64)
Query Neighborhood Hits	246	Target Neighborhood Hits	225	Shared Neighborhood Hits	95
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS2_HUMAN
θ value	6.41864e-14 (rank : 70)	NC score	0.470346 (rank : 65)
Query Neighborhood Hits	246	Target Neighborhood Hits	179	Shared Neighborhood Hits	84
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

GPR97_MOUSE
θ value	8.38298e-14 (rank : 71)	NC score	0.632065 (rank : 21)
Query Neighborhood Hits	246	Target Neighborhood Hits	89	Shared Neighborhood Hits	79
SwissProt Accessions	Q8R0T6	Gene names	Gpr97
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor.

GP125_HUMAN
θ value	1.09485e-13 (rank : 72)	NC score	0.337860 (rank : 134)
Query Neighborhood Hits	246	Target Neighborhood Hits	327	Shared Neighborhood Hits	50
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

ATS12_HUMAN
θ value	4.16044e-13 (rank : 73)	NC score	0.456482 (rank : 78)
Query Neighborhood Hits	246	Target Neighborhood Hits	251	Shared Neighborhood Hits	90
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS14_HUMAN
θ value	3.52202e-12 (rank : 74)	NC score	0.462345 (rank : 70)
Query Neighborhood Hits	246	Target Neighborhood Hits	382	Shared Neighborhood Hits	82
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

GPR56_MOUSE
θ value	3.52202e-12 (rank : 75)	NC score	0.588439 (rank : 34)
Query Neighborhood Hits	246	Target Neighborhood Hits	89	Shared Neighborhood Hits	78
SwissProt Accessions	Q8K209, Q3UR17, Q9QZT2	Gene names	Gpr56, Cyt28
Domain Architecture
Description	G-protein coupled receptor 56 precursor (Serpentine receptor cyt28).

ATS12_MOUSE
θ value	4.59992e-12 (rank : 76)	NC score	0.457938 (rank : 77)
Query Neighborhood Hits	246	Target Neighborhood Hits	220	Shared Neighborhood Hits	94
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS7_HUMAN
θ value	6.00763e-12 (rank : 77)	NC score	0.447118 (rank : 90)
Query Neighborhood Hits	246	Target Neighborhood Hits	169	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

GP128_MOUSE
θ value	6.00763e-12 (rank : 78)	NC score	0.621214 (rank : 25)
Query Neighborhood Hits	246	Target Neighborhood Hits	141	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BM96, Q80T42	Gene names	Gpr128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

ATL2_MOUSE
θ value	1.02475e-11 (rank : 79)	NC score	0.521688 (rank : 48)
Query Neighborhood Hits	246	Target Neighborhood Hits	137	Shared Neighborhood Hits	80
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

GPR97_HUMAN
θ value	1.02475e-11 (rank : 80)	NC score	0.604007 (rank : 29)
Query Neighborhood Hits	246	Target Neighborhood Hits	86	Shared Neighborhood Hits	75
SwissProt Accessions	Q86Y34, Q6ZMF4, Q86SL9, Q8IZF1	Gene names	GPR97, PGR26
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor (G-protein coupled receptor PGR26).

GP115_MOUSE
θ value	1.33837e-11 (rank : 81)	NC score	0.595914 (rank : 33)
Query Neighborhood Hits	246	Target Neighborhood Hits	69	Shared Neighborhood Hits	63
SwissProt Accessions	Q9D2L6	Gene names	Gpr115
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 precursor.

GPR56_HUMAN
θ value	1.33837e-11 (rank : 82)	NC score	0.606311 (rank : 28)
Query Neighborhood Hits	246	Target Neighborhood Hits	84	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y653, O95966, Q8NGB3, Q96HB4	Gene names	GPR56, TM7LN4, TM7XN1
Domain Architecture
Description	G-protein coupled receptor 56 precursor (TM7XN1 protein).

GP125_MOUSE
θ value	2.28291e-11 (rank : 83)	NC score	0.315931 (rank : 142)
Query Neighborhood Hits	246	Target Neighborhood Hits	329	Shared Neighborhood Hits	49
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

ATS3_HUMAN
θ value	2.98157e-11 (rank : 84)	NC score	0.449004 (rank : 89)
Query Neighborhood Hits	246	Target Neighborhood Hits	179	Shared Neighborhood Hits	89
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

CRFR2_HUMAN
θ value	5.08577e-11 (rank : 85)	NC score	0.451167 (rank : 85)
Query Neighborhood Hits	246	Target Neighborhood Hits	76	Shared Neighborhood Hits	73
SwissProt Accessions	Q13324, O43461, Q99431	Gene names	CRHR2, CRF2R, CRH2R
Domain Architecture
Description	Corticotropin-releasing factor receptor 2 precursor (CRF-R 2) (CRF2) (Corticotropin-releasing hormone receptor 2) (CRH-R 2).

ATL2_HUMAN
θ value	6.64225e-11 (rank : 86)	NC score	0.519647 (rank : 49)
Query Neighborhood Hits	246	Target Neighborhood Hits	125	Shared Neighborhood Hits	77
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

CRFR2_MOUSE
θ value	6.64225e-11 (rank : 87)	NC score	0.454799 (rank : 79)
Query Neighborhood Hits	246	Target Neighborhood Hits	76	Shared Neighborhood Hits	73
SwissProt Accessions	Q60748, Q60783, Q60808	Gene names	Crhr2, Crf2r
Domain Architecture
Description	Corticotropin-releasing factor receptor 2 precursor (CRF-R 2) (CRF2) (Corticotropin-releasing hormone receptor 2) (CRH-R 2) (CRF-RB) (CRH- R2).

CRFR1_MOUSE
θ value	8.67504e-11 (rank : 88)	NC score	0.458332 (rank : 75)
Query Neighborhood Hits	246	Target Neighborhood Hits	83	Shared Neighborhood Hits	74
SwissProt Accessions	P35347	Gene names	Crhr1, Crhr
Domain Architecture
Description	Corticotropin-releasing factor receptor 1 precursor (CRF-R) (CRF1) (Corticotropin-releasing hormone receptor 1) (CRH-R 1).

CRFR1_HUMAN
θ value	1.133e-10 (rank : 89)	NC score	0.452948 (rank : 82)
Query Neighborhood Hits	246	Target Neighborhood Hits	82	Shared Neighborhood Hits	73
SwissProt Accessions	P34998, Q13008, Q9UK64	Gene names	CRHR1, CRFR, CRFR1, CRHR
Domain Architecture
Description	Corticotropin-releasing factor receptor 1 precursor (CRF-R) (CRF1) (Corticotropin-releasing hormone receptor 1) (CRH-R 1).

ATS1_MOUSE
θ value	3.29651e-10 (rank : 90)	NC score	0.450061 (rank : 87)
Query Neighborhood Hits	246	Target Neighborhood Hits	158	Shared Neighborhood Hits	84
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

GPR98_MOUSE
θ value	5.62301e-10 (rank : 91)	NC score	0.427564 (rank : 100)
Query Neighborhood Hits	246	Target Neighborhood Hits	206	Shared Neighborhood Hits	78
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

CO6_HUMAN
θ value	7.34386e-10 (rank : 92)	NC score	0.397967 (rank : 105)
Query Neighborhood Hits	246	Target Neighborhood Hits	331	Shared Neighborhood Hits	98
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CALCR_HUMAN
θ value	9.59137e-10 (rank : 93)	NC score	0.418195 (rank : 103)
Query Neighborhood Hits	246	Target Neighborhood Hits	67	Shared Neighborhood Hits	64
SwissProt Accessions	P30988, O14585, Q13941, Q6DJU8, Q6T712	Gene names	CALCR
Domain Architecture
Description	Calcitonin receptor precursor (CT-R).

GP111_HUMAN
θ value	2.13673e-09 (rank : 94)	NC score	0.547699 (rank : 38)
Query Neighborhood Hits	246	Target Neighborhood Hits	77	Shared Neighborhood Hits	58
SwissProt Accessions	Q8IZF7, Q86SL6, Q8NGU5, Q8TDT5	Gene names	GPR111, PGR20
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 111 (G-protein coupled receptor PGR20).

ATS1_HUMAN
θ value	3.64472e-09 (rank : 95)	NC score	0.447106 (rank : 91)
Query Neighborhood Hits	246	Target Neighborhood Hits	159	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

GP124_MOUSE
θ value	6.21693e-09 (rank : 96)	NC score	0.327029 (rank : 139)
Query Neighborhood Hits	246	Target Neighborhood Hits	423	Shared Neighborhood Hits	54
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

ATS4_MOUSE
θ value	1.80886e-08 (rank : 97)	NC score	0.451751 (rank : 84)
Query Neighborhood Hits	246	Target Neighborhood Hits	145	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

VIPR2_HUMAN
θ value	1.80886e-08 (rank : 98)	NC score	0.391181 (rank : 109)
Query Neighborhood Hits	246	Target Neighborhood Hits	97	Shared Neighborhood Hits	72
SwissProt Accessions	P41587, Q13053, Q15870	Gene names	VIPR2, VIP2R
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) (Helodermin-preferring VIP receptor).

ATS4_HUMAN
θ value	2.36244e-08 (rank : 99)	NC score	0.452417 (rank : 83)
Query Neighborhood Hits	246	Target Neighborhood Hits	138	Shared Neighborhood Hits	77
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

ATS13_HUMAN
θ value	3.08544e-08 (rank : 100)	NC score	0.479957 (rank : 60)
Query Neighborhood Hits	246	Target Neighborhood Hits	238	Shared Neighborhood Hits	84
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

GP124_HUMAN
θ value	4.0297e-08 (rank : 101)	NC score	0.302113 (rank : 146)
Query Neighborhood Hits	246	Target Neighborhood Hits	304	Shared Neighborhood Hits	49
SwissProt Accessions	Q96PE1, Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4	Gene names	GPR124, KIAA1531, TEM5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

ATS13_MOUSE
θ value	6.87365e-08 (rank : 102)	NC score	0.476190 (rank : 63)
Query Neighborhood Hits	246	Target Neighborhood Hits	227	Shared Neighborhood Hits	88
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS15_HUMAN
θ value	6.87365e-08 (rank : 103)	NC score	0.439746 (rank : 94)
Query Neighborhood Hits	246	Target Neighborhood Hits	151	Shared Neighborhood Hits	81
SwissProt Accessions	Q8TE58	Gene names	ADAMTS15
Domain Architecture
Description	ADAMTS-15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 15) (ADAM-TS 15) (ADAM-TS15).

GPR98_HUMAN
θ value	6.87365e-08 (rank : 104)	NC score	0.436815 (rank : 95)
Query Neighborhood Hits	246	Target Neighborhood Hits	202	Shared Neighborhood Hits	82
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

ATS8_HUMAN
θ value	8.97725e-08 (rank : 105)	NC score	0.449089 (rank : 88)
Query Neighborhood Hits	246	Target Neighborhood Hits	145	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

ATS8_MOUSE
θ value	8.97725e-08 (rank : 106)	NC score	0.452965 (rank : 81)
Query Neighborhood Hits	246	Target Neighborhood Hits	139	Shared Neighborhood Hits	78
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

VIPR2_MOUSE
θ value	1.17247e-07 (rank : 107)	NC score	0.394557 (rank : 107)
Query Neighborhood Hits	246	Target Neighborhood Hits	98	Shared Neighborhood Hits	73
SwissProt Accessions	P41588, P97750	Gene names	Vipr2
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3).

GP114_HUMAN
θ value	1.99992e-07 (rank : 108)	NC score	0.601973 (rank : 30)
Query Neighborhood Hits	246	Target Neighborhood Hits	75	Shared Neighborhood Hits	72
SwissProt Accessions	Q8IZF4, Q6ZMH7, Q6ZML4, Q86SL8, Q8IZ14	Gene names	GPR114, PGR27
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 114 precursor (G-protein coupled receptor PGR27).

ATS5_MOUSE
θ value	3.41135e-07 (rank : 109)	NC score	0.429830 (rank : 99)
Query Neighborhood Hits	246	Target Neighborhood Hits	147	Shared Neighborhood Hits	79
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

UNC5A_HUMAN
θ value	3.41135e-07 (rank : 110)	NC score	0.415160 (rank : 104)
Query Neighborhood Hits	246	Target Neighborhood Hits	198	Shared Neighborhood Hits	73
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

PACR_MOUSE
θ value	4.45536e-07 (rank : 111)	NC score	0.388960 (rank : 110)
Query Neighborhood Hits	246	Target Neighborhood Hits	83	Shared Neighborhood Hits	74
SwissProt Accessions	P70205	Gene names	Adcyap1r1
Domain Architecture
Description	Pituitary adenylate cyclase-activating polypeptide type I receptor precursor (PACAP type I receptor) (PACAP-R-1).

ATS6_HUMAN
θ value	5.81887e-07 (rank : 112)	NC score	0.445728 (rank : 92)
Query Neighborhood Hits	246	Target Neighborhood Hits	141	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

CO8B_HUMAN
θ value	9.92553e-07 (rank : 113)	NC score	0.359838 (rank : 120)
Query Neighborhood Hits	246	Target Neighborhood Hits	199	Shared Neighborhood Hits	73
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

VIPR1_MOUSE
θ value	9.92553e-07 (rank : 114)	NC score	0.393434 (rank : 108)
Query Neighborhood Hits	246	Target Neighborhood Hits	89	Shared Neighborhood Hits	76
SwissProt Accessions	P97751, Q9JI40, Q9R1T8	Gene names	Vipr1
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 1 precursor (VIP-R-1) (VPAC1) (Pituitary adenylate cyclase-activating polypeptide type II receptor) (PACAP type II receptor) (PACAP-R-2).

CALCR_MOUSE
θ value	1.29631e-06 (rank : 115)	NC score	0.395859 (rank : 106)
Query Neighborhood Hits	246	Target Neighborhood Hits	76	Shared Neighborhood Hits	68
SwissProt Accessions	Q60755	Gene names	Calcr
Domain Architecture
Description	Calcitonin receptor precursor (CT-R).

GP123_HUMAN
θ value	1.29631e-06 (rank : 116)	NC score	0.445115 (rank : 93)
Query Neighborhood Hits	246	Target Neighborhood Hits	120	Shared Neighborhood Hits	47
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

ATL1_HUMAN
θ value	1.69304e-06 (rank : 117)	NC score	0.462969 (rank : 69)
Query Neighborhood Hits	246	Target Neighborhood Hits	93	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N6G6, Q5T708, Q96RW4, Q9BXY3	Gene names	ADAMTSL1, ADAMTSR1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (ADAMTSL-1) (Punctin-1).

CILP1_MOUSE
θ value	1.69304e-06 (rank : 118)	NC score	0.312002 (rank : 143)
Query Neighborhood Hits	246	Target Neighborhood Hits	282	Shared Neighborhood Hits	79
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CO8B_MOUSE
θ value	2.21117e-06 (rank : 119)	NC score	0.381181 (rank : 112)
Query Neighborhood Hits	246	Target Neighborhood Hits	224	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

ATL1_MOUSE
θ value	2.88788e-06 (rank : 120)	NC score	0.460588 (rank : 71)
Query Neighborhood Hits	246	Target Neighborhood Hits	80	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BLI0	Gene names	Adamtsl1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (Punctin-1).

CILP2_HUMAN
θ value	2.88788e-06 (rank : 121)	NC score	0.382126 (rank : 111)
Query Neighborhood Hits	246	Target Neighborhood Hits	307	Shared Neighborhood Hits	81
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

ATS5_HUMAN
θ value	6.43352e-06 (rank : 122)	NC score	0.421699 (rank : 102)
Query Neighborhood Hits	246	Target Neighborhood Hits	141	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

GLR_HUMAN
θ value	6.43352e-06 (rank : 123)	NC score	0.355547 (rank : 122)
Query Neighborhood Hits	246	Target Neighborhood Hits	77	Shared Neighborhood Hits	69
SwissProt Accessions	P47871	Gene names	GCGR
Domain Architecture
Description	Glucagon receptor precursor (GL-R).

PTHR1_MOUSE
θ value	1.87187e-05 (rank : 124)	NC score	0.362212 (rank : 118)
Query Neighborhood Hits	246	Target Neighborhood Hits	90	Shared Neighborhood Hits	72
SwissProt Accessions	P41593, Q62119	Gene names	Pthr1, Pthr
Domain Architecture
Description	Parathyroid hormone/parathyroid hormone-related peptide receptor precursor (PTH/PTHr receptor) (PTH/PTHrP type I receptor).

THSD1_HUMAN
θ value	3.19293e-05 (rank : 125)	NC score	0.436009 (rank : 97)
Query Neighborhood Hits	246	Target Neighborhood Hits	136	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

THSD1_MOUSE
θ value	3.19293e-05 (rank : 126)	NC score	0.426709 (rank : 101)
Query Neighborhood Hits	246	Target Neighborhood Hits	153	Shared Neighborhood Hits	75
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

VIPR1_HUMAN
θ value	3.19293e-05 (rank : 127)	NC score	0.372756 (rank : 114)
Query Neighborhood Hits	246	Target Neighborhood Hits	84	Shared Neighborhood Hits	71
SwissProt Accessions	P32241, Q15871	Gene names	VIPR1
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 1 precursor (VIP-R-1) (Pituitary adenylate cyclase-activating polypeptide type II receptor) (PACAP type II receptor) (PACAP-R-2).

PTHR1_HUMAN
θ value	5.44631e-05 (rank : 128)	NC score	0.376780 (rank : 113)
Query Neighborhood Hits	246	Target Neighborhood Hits	85	Shared Neighborhood Hits	74
SwissProt Accessions	Q03431	Gene names	PTHR1, PTHR
Domain Architecture
Description	Parathyroid hormone/parathyroid hormone-related peptide receptor precursor (PTH/PTHr receptor) (PTH/PTHrP type I receptor).

ATL5_HUMAN
θ value	7.1131e-05 (rank : 129)	NC score	0.463088 (rank : 68)
Query Neighborhood Hits	246	Target Neighborhood Hits	103	Shared Neighborhood Hits	75
SwissProt Accessions	Q6ZMM2, Q8IW95	Gene names	ADAMTSL5, THSD6
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 5 precursor (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6).

CO7_HUMAN
θ value	0.000121331 (rank : 130)	NC score	0.336263 (rank : 136)
Query Neighborhood Hits	246	Target Neighborhood Hits	278	Shared Neighborhood Hits	82
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

GLR_MOUSE
θ value	0.000158464 (rank : 131)	NC score	0.338165 (rank : 132)
Query Neighborhood Hits	246	Target Neighborhood Hits	79	Shared Neighborhood Hits	68
SwissProt Accessions	Q61606, Q63960	Gene names	Gcgr
Domain Architecture
Description	Glucagon receptor precursor (GL-R).

CI094_HUMAN
θ value	0.000461057 (rank : 132)	NC score	0.362311 (rank : 117)
Query Neighborhood Hits	246	Target Neighborhood Hits	310	Shared Neighborhood Hits	73
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

CILP1_HUMAN
θ value	0.000461057 (rank : 133)	NC score	0.293228 (rank : 147)
Query Neighborhood Hits	246	Target Neighborhood Hits	266	Shared Neighborhood Hits	81
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

SCTR_MOUSE
θ value	0.000461057 (rank : 134)	NC score	0.337941 (rank : 133)
Query Neighborhood Hits	246	Target Neighborhood Hits	69	Shared Neighborhood Hits	68
SwissProt Accessions	Q5FWI2, Q80T66	Gene names	Sctr
Domain Architecture	No domain graphic available
Description	Secretin receptor precursor (SCT-R).

PACR_HUMAN
θ value	0.00134147 (rank : 135)	NC score	0.371456 (rank : 115)
Query Neighborhood Hits	246	Target Neighborhood Hits	86	Shared Neighborhood Hits	76
SwissProt Accessions	P41586	Gene names	ADCYAP1R1
Domain Architecture
Description	Pituitary adenylate cyclase-activating polypeptide type I receptor precursor (PACAP type I receptor) (PACAP-R-1).

FZD3_HUMAN
θ value	0.00175202 (rank : 136)	NC score	0.100723 (rank : 190)
Query Neighborhood Hits	246	Target Neighborhood Hits	74	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NPG1	Gene names	FZD3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (hFz3).

GHRHR_HUMAN
θ value	0.00175202 (rank : 137)	NC score	0.344686 (rank : 129)
Query Neighborhood Hits	246	Target Neighborhood Hits	78	Shared Neighborhood Hits	72
SwissProt Accessions	Q02643, Q99863	Gene names	GHRHR
Domain Architecture
Description	Growth hormone-releasing hormone receptor precursor (GHRH receptor) (GRF receptor) (GRFR).

GHRHR_MOUSE
θ value	0.00175202 (rank : 138)	NC score	0.331823 (rank : 137)
Query Neighborhood Hits	246	Target Neighborhood Hits	79	Shared Neighborhood Hits	71
SwissProt Accessions	P32082	Gene names	Ghrhr, Grfr
Domain Architecture	No domain graphic available
Description	Growth hormone-releasing hormone receptor precursor (GHRH receptor) (GRF receptor) (GRFR).

FZD3_MOUSE
θ value	0.00228821 (rank : 139)	NC score	0.099497 (rank : 199)
Query Neighborhood Hits	246	Target Neighborhood Hits	75	Shared Neighborhood Hits	29
SwissProt Accessions	Q61086	Gene names	Fzd3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (mFz3).

CALRL_HUMAN
θ value	0.00298849 (rank : 140)	NC score	0.366776 (rank : 116)
Query Neighborhood Hits	246	Target Neighborhood Hits	71	Shared Neighborhood Hits	67
SwissProt Accessions	Q16602	Gene names	CALCRL, CGRPR
Domain Architecture
Description	Calcitonin gene-related peptide type 1 receptor precursor (CGRP type 1 receptor) (Calcitonin receptor-like receptor).

GLP1R_MOUSE
θ value	0.00298849 (rank : 141)	NC score	0.354074 (rank : 123)
Query Neighborhood Hits	246	Target Neighborhood Hits	80	Shared Neighborhood Hits	69
SwissProt Accessions	O35659	Gene names	Glp1r
Domain Architecture
Description	Glucagon-like peptide 1 receptor precursor (GLP-1 receptor) (GLP-1-R) (GLP-1R).

CO8A_MOUSE
θ value	0.00390308 (rank : 142)	NC score	0.339977 (rank : 131)
Query Neighborhood Hits	246	Target Neighborhood Hits	182	Shared Neighborhood Hits	73
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

FRAS1_MOUSE
θ value	0.00509761 (rank : 143)	NC score	0.121405 (rank : 167)
Query Neighborhood Hits	246	Target Neighborhood Hits	747	Shared Neighborhood Hits	96
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FZD6_MOUSE
θ value	0.00509761 (rank : 144)	NC score	0.082809 (rank : 278)
Query Neighborhood Hits	246	Target Neighborhood Hits	135	Shared Neighborhood Hits	28
SwissProt Accessions	Q61089	Gene names	Fzd6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (mFz6).

SCTR_HUMAN
θ value	0.00665767 (rank : 145)	NC score	0.352270 (rank : 127)
Query Neighborhood Hits	246	Target Neighborhood Hits	70	Shared Neighborhood Hits	67
SwissProt Accessions	P47872, Q12961, Q13213	Gene names	SCTR
Domain Architecture
Description	Secretin receptor precursor (SCT-R).

FZD6_HUMAN
θ value	0.00869519 (rank : 146)	NC score	0.085851 (rank : 267)
Query Neighborhood Hits	246	Target Neighborhood Hits	84	Shared Neighborhood Hits	29
SwissProt Accessions	O60353, Q6P9C3	Gene names	FZD6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (hFz6).

LYAM2_HUMAN
θ value	0.00869519 (rank : 147)	NC score	0.071002 (rank : 314)
Query Neighborhood Hits	246	Target Neighborhood Hits	394	Shared Neighborhood Hits	46
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

GIPR_HUMAN
θ value	0.0113563 (rank : 148)	NC score	0.327883 (rank : 138)
Query Neighborhood Hits	246	Target Neighborhood Hits	71	Shared Neighborhood Hits	69
SwissProt Accessions	P48546, Q14401, Q16400, Q9UPI1	Gene names	GIPR
Domain Architecture
Description	Gastric inhibitory polypeptide receptor precursor (GIP-R) (Glucose- dependent insulinotropic polypeptide receptor).

O10A5_HUMAN
θ value	0.0113563 (rank : 149)	NC score	0.000450 (rank : 485)
Query Neighborhood Hits	246	Target Neighborhood Hits	767	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H207, Q52M66, Q96R22	Gene names	OR10A5
Domain Architecture
Description	Olfactory receptor 10A5 (HP3) (Olfactory receptor-like protein JCG6).

RSPO1_HUMAN
θ value	0.0113563 (rank : 150)	NC score	0.158142 (rank : 152)
Query Neighborhood Hits	246	Target Neighborhood Hits	101	Shared Neighborhood Hits	52
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

CALRL_MOUSE
θ value	0.0148317 (rank : 151)	NC score	0.362028 (rank : 119)
Query Neighborhood Hits	246	Target Neighborhood Hits	71	Shared Neighborhood Hits	67
SwissProt Accessions	Q9R1W5, Q9QXH8, Q9WUP2	Gene names	Calcrl, Crlr
Domain Architecture
Description	Calcitonin gene-related peptide type 1 receptor precursor (CGRP type 1 receptor) (Calcitonin receptor-like receptor).

GLP1R_HUMAN
θ value	0.0148317 (rank : 152)	NC score	0.341063 (rank : 130)
Query Neighborhood Hits	246	Target Neighborhood Hits	84	Shared Neighborhood Hits	67
SwissProt Accessions	P43220, Q99669	Gene names	GLP1R
Domain Architecture
Description	Glucagon-like peptide 1 receptor precursor (GLP-1 receptor) (GLP-1-R) (GLP-1R).

GLP2R_HUMAN
θ value	0.0148317 (rank : 153)	NC score	0.310354 (rank : 144)
Query Neighborhood Hits	246	Target Neighborhood Hits	75	Shared Neighborhood Hits	70
SwissProt Accessions	O95838	Gene names	GLP2R
Domain Architecture
Description	Glucagon-like peptide 2 receptor precursor (GLP-2 receptor) (GLP-2-R) (GLP-2R).

OR4B1_HUMAN
θ value	0.0148317 (rank : 154)	NC score	0.004348 (rank : 478)
Query Neighborhood Hits	246	Target Neighborhood Hits	652	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NGF8, Q6IF75, Q96R64	Gene names	OR4B1
Domain Architecture
Description	Olfactory receptor 4B1 (OST208) (Olfactory receptor OR11-106).

FRAS1_HUMAN
θ value	0.0961366 (rank : 155)	NC score	0.111830 (rank : 175)
Query Neighborhood Hits	246	Target Neighborhood Hits	759	Shared Neighborhood Hits	89
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

KR101_HUMAN
θ value	0.125558 (rank : 156)	NC score	0.079829 (rank : 284)
Query Neighborhood Hits	246	Target Neighborhood Hits	261	Shared Neighborhood Hits	43
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

WISP1_MOUSE
θ value	0.125558 (rank : 157)	NC score	0.124176 (rank : 165)
Query Neighborhood Hits	246	Target Neighborhood Hits	123	Shared Neighborhood Hits	52
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

O10A4_HUMAN
θ value	0.163984 (rank : 158)	NC score	-0.000072 (rank : 488)
Query Neighborhood Hits	246	Target Neighborhood Hits	686	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H209, Q96R20	Gene names	OR10A4
Domain Architecture
Description	Olfactory receptor 10A4 (HP2) (Olfactory receptor-like protein JCG5).

CO8A_HUMAN
θ value	0.21417 (rank : 159)	NC score	0.337857 (rank : 135)
Query Neighborhood Hits	246	Target Neighborhood Hits	200	Shared Neighborhood Hits	77
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

KRA45_HUMAN
θ value	0.21417 (rank : 160)	NC score	0.057354 (rank : 379)
Query Neighborhood Hits	246	Target Neighborhood Hits	194	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

MGR7_HUMAN
θ value	0.21417 (rank : 161)	NC score	0.018876 (rank : 461)
Query Neighborhood Hits	246	Target Neighborhood Hits	52	Shared Neighborhood Hits	7
SwissProt Accessions	Q14831, Q8NFS2, Q8NFS3, Q8NFS4	Gene names	GRM7, GPRC1G, MGLUR7
Domain Architecture
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

OL142_MOUSE
θ value	0.21417 (rank : 162)	NC score	-0.000910 (rank : 490)
Query Neighborhood Hits	246	Target Neighborhood Hits	756	Shared Neighborhood Hits	11
SwissProt Accessions	Q60881, Q8VGP2	Gene names	Olfr142, Mor227-2, Olfr4
Domain Architecture	No domain graphic available
Description	Olfactory receptor 142 (Olfactory receptor 4C) (Olfactory receptor 227-2).

ZAN_MOUSE
θ value	0.21417 (rank : 163)	NC score	0.096923 (rank : 214)
Query Neighborhood Hits	246	Target Neighborhood Hits	808	Shared Neighborhood Hits	82
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

MGR7_MOUSE
θ value	0.279714 (rank : 164)	NC score	0.018469 (rank : 462)
Query Neighborhood Hits	246	Target Neighborhood Hits	53	Shared Neighborhood Hits	7
SwissProt Accessions	Q68ED2	Gene names	Grm7, Gprc1g, Mglur7
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

O10J6_HUMAN
θ value	0.279714 (rank : 165)	NC score	0.002007 (rank : 483)
Query Neighborhood Hits	246	Target Neighborhood Hits	732	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NGY7, Q96R55	Gene names	OR10J6
Domain Architecture
Description	Olfactory receptor 10J6.

WISP1_HUMAN
θ value	0.279714 (rank : 166)	NC score	0.115442 (rank : 171)
Query Neighborhood Hits	246	Target Neighborhood Hits	121	Shared Neighborhood Hits	55
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

MRCKA_HUMAN
θ value	0.365318 (rank : 167)	NC score	-0.009229 (rank : 500)
Query Neighborhood Hits	246	Target Neighborhood Hits	1999	Shared Neighborhood Hits	12
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

RSPO1_MOUSE
θ value	0.365318 (rank : 168)	NC score	0.137302 (rank : 160)
Query Neighborhood Hits	246	Target Neighborhood Hits	85	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

LRP4_HUMAN
θ value	0.62314 (rank : 169)	NC score	0.063714 (rank : 344)
Query Neighborhood Hits	246	Target Neighborhood Hits	355	Shared Neighborhood Hits	43
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

PCSK5_MOUSE
θ value	0.62314 (rank : 170)	NC score	0.068171 (rank : 324)
Query Neighborhood Hits	246	Target Neighborhood Hits	613	Shared Neighborhood Hits	70
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

CTNS_MOUSE
θ value	0.813845 (rank : 171)	NC score	0.034033 (rank : 457)
Query Neighborhood Hits	246	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	P57757	Gene names	Ctns
Domain Architecture
Description	Cystinosin.

CYR61_HUMAN
θ value	0.813845 (rank : 172)	NC score	0.096557 (rank : 221)
Query Neighborhood Hits	246	Target Neighborhood Hits	159	Shared Neighborhood Hits	58
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

FZD1_MOUSE
θ value	0.813845 (rank : 173)	NC score	0.052766 (rank : 415)
Query Neighborhood Hits	246	Target Neighborhood Hits	63	Shared Neighborhood Hits	30
SwissProt Accessions	O70421, O08974	Gene names	Fzd1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (mFz1).

KR10A_HUMAN
θ value	0.813845 (rank : 174)	NC score	0.051559 (rank : 431)
Query Neighborhood Hits	246	Target Neighborhood Hits	232	Shared Neighborhood Hits	36
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

OR4D1_HUMAN
θ value	0.813845 (rank : 175)	NC score	-0.000391 (rank : 489)
Query Neighborhood Hits	246	Target Neighborhood Hits	804	Shared Neighborhood Hits	13
SwissProt Accessions	Q15615, Q8NGB1, Q96R76	Gene names	OR4D1, OR4D3
Domain Architecture
Description	Olfactory receptor 4D1 (Olfactory receptor TPCR16).

SPON2_HUMAN
θ value	0.813845 (rank : 176)	NC score	0.190171 (rank : 151)
Query Neighborhood Hits	246	Target Neighborhood Hits	53	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BUD6, Q9ULW1	Gene names	SPON2, DIL1
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin) (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1).

CTNS_HUMAN
θ value	1.06291 (rank : 177)	NC score	0.032403 (rank : 458)
Query Neighborhood Hits	246	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	O60931, Q9UNK6	Gene names	CTNS
Domain Architecture
Description	Cystinosin.

FBN1_HUMAN
θ value	1.38821 (rank : 178)	NC score	0.103376 (rank : 187)
Query Neighborhood Hits	246	Target Neighborhood Hits	557	Shared Neighborhood Hits	65
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

KR414_HUMAN
θ value	1.38821 (rank : 179)	NC score	0.085783 (rank : 268)
Query Neighborhood Hits	246	Target Neighborhood Hits	199	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

LRP4_MOUSE
θ value	1.38821 (rank : 180)	NC score	0.063263 (rank : 348)
Query Neighborhood Hits	246	Target Neighborhood Hits	351	Shared Neighborhood Hits	45
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

MGR8_HUMAN
θ value	1.38821 (rank : 181)	NC score	0.015652 (rank : 466)
Query Neighborhood Hits	246	Target Neighborhood Hits	49	Shared Neighborhood Hits	7
SwissProt Accessions	O00222, O15493, O95945, O95946, Q3MIV9, Q52M02, Q6J165	Gene names	GRM8, GPRC1H, MGLUR8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

MGR8_MOUSE
θ value	1.38821 (rank : 182)	NC score	0.015644 (rank : 467)
Query Neighborhood Hits	246	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	P47743, Q6B964	Gene names	Grm8, Gprc1h, Mglur8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

PCSK5_HUMAN
θ value	1.38821 (rank : 183)	NC score	0.040585 (rank : 451)
Query Neighborhood Hits	246	Target Neighborhood Hits	291	Shared Neighborhood Hits	39
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

RSPO4_HUMAN
θ value	1.38821 (rank : 184)	NC score	0.099294 (rank : 200)
Query Neighborhood Hits	246	Target Neighborhood Hits	110	Shared Neighborhood Hits	40
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

STAB2_MOUSE
θ value	1.38821 (rank : 185)	NC score	0.098279 (rank : 204)
Query Neighborhood Hits	246	Target Neighborhood Hits	528	Shared Neighborhood Hits	66
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

C163B_HUMAN
θ value	1.81305 (rank : 186)	NC score	0.004149 (rank : 479)
Query Neighborhood Hits	246	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NR16, Q6UWC2	Gene names	CD163L1, CD163B, M160
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M160 precursor (CD163 antigen-like 1) (CD163b antigen).

FZD5_HUMAN
θ value	1.81305 (rank : 187)	NC score	0.046170 (rank : 446)
Query Neighborhood Hits	246	Target Neighborhood Hits	71	Shared Neighborhood Hits	25
SwissProt Accessions	Q13467, Q53R22	Gene names	FZD5, HFZ5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (hFz5) (FzE5).

FZD5_MOUSE
θ value	1.81305 (rank : 188)	NC score	0.044678 (rank : 448)
Query Neighborhood Hits	246	Target Neighborhood Hits	70	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EQD0, O08975, Q8BMR2, Q8CHK9	Gene names	Fzd5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (mFz5).

KR102_HUMAN
θ value	1.81305 (rank : 189)	NC score	0.073242 (rank : 309)
Query Neighborhood Hits	246	Target Neighborhood Hits	264	Shared Neighborhood Hits	43
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KRA44_HUMAN
θ value	1.81305 (rank : 190)	NC score	0.041489 (rank : 450)
Query Neighborhood Hits	246	Target Neighborhood Hits	162	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

OR4L1_HUMAN
θ value	1.81305 (rank : 191)	NC score	-0.001308 (rank : 491)
Query Neighborhood Hits	246	Target Neighborhood Hits	784	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NH43, Q6IEZ5	Gene names	OR4L1
Domain Architecture
Description	Olfactory receptor 4L1 (Olfactory receptor OR14-28).

RSPO3_HUMAN
θ value	1.81305 (rank : 192)	NC score	0.124473 (rank : 164)
Query Neighborhood Hits	246	Target Neighborhood Hits	128	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

RSPO3_MOUSE
θ value	1.81305 (rank : 193)	NC score	0.126510 (rank : 163)
Query Neighborhood Hits	246	Target Neighborhood Hits	120	Shared Neighborhood Hits	43
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

SPON2_MOUSE
θ value	1.81305 (rank : 194)	NC score	0.150495 (rank : 156)
Query Neighborhood Hits	246	Target Neighborhood Hits	42	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).

CSMD3_HUMAN
θ value	2.36792 (rank : 195)	NC score	0.013325 (rank : 469)
Query Neighborhood Hits	246	Target Neighborhood Hits	199	Shared Neighborhood Hits	18
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CYR61_MOUSE
θ value	2.36792 (rank : 196)	NC score	0.078870 (rank : 293)
Query Neighborhood Hits	246	Target Neighborhood Hits	156	Shared Neighborhood Hits	53
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

KRA42_HUMAN
θ value	2.36792 (rank : 197)	NC score	0.046167 (rank : 447)
Query Neighborhood Hits	246	Target Neighborhood Hits	149	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

PTHR2_HUMAN
θ value	2.36792 (rank : 198)	NC score	0.304605 (rank : 145)
Query Neighborhood Hits	246	Target Neighborhood Hits	81	Shared Neighborhood Hits	67
SwissProt Accessions	P49190, Q8N429	Gene names	PTHR2
Domain Architecture
Description	Parathyroid hormone receptor precursor (PTH2 receptor).

SORL_HUMAN
θ value	2.36792 (rank : 199)	NC score	0.038056 (rank : 453)
Query Neighborhood Hits	246	Target Neighborhood Hits	440	Shared Neighborhood Hits	41
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SPB8_MOUSE
θ value	2.36792 (rank : 200)	NC score	0.001831 (rank : 484)
Query Neighborhood Hits	246	Target Neighborhood Hits	84	Shared Neighborhood Hits	4
SwissProt Accessions	O08800	Gene names	Serpinb8
Domain Architecture	No domain graphic available
Description	Serpin B8.

UN13B_MOUSE
θ value	2.36792 (rank : 201)	NC score	0.014754 (rank : 468)
Query Neighborhood Hits	246	Target Neighborhood Hits	210	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

ATRX_HUMAN
θ value	3.0926 (rank : 202)	NC score	-0.001645 (rank : 492)
Query Neighborhood Hits	246	Target Neighborhood Hits	842	Shared Neighborhood Hits	5
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

CUBN_MOUSE
θ value	3.0926 (rank : 203)	NC score	0.096508 (rank : 222)
Query Neighborhood Hits	246	Target Neighborhood Hits	477	Shared Neighborhood Hits	53
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

DYH9_HUMAN
θ value	3.0926 (rank : 204)	NC score	0.006290 (rank : 475)
Query Neighborhood Hits	246	Target Neighborhood Hits	291	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NYC9, O95494, Q9NQ28	Gene names	DNAH9, DNAH17L, DNAL1
Domain Architecture
Description	Ciliary dynein heavy chain 9 (Axonemal beta dynein heavy chain 9).

KR106_HUMAN
θ value	3.0926 (rank : 205)	NC score	0.086460 (rank : 262)
Query Neighborhood Hits	246	Target Neighborhood Hits	347	Shared Neighborhood Hits	57
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

LDLR_MOUSE
θ value	3.0926 (rank : 206)	NC score	0.063914 (rank : 340)
Query Neighborhood Hits	246	Target Neighborhood Hits	382	Shared Neighborhood Hits	51
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LYAM3_HUMAN
θ value	3.0926 (rank : 207)	NC score	0.049635 (rank : 444)
Query Neighborhood Hits	246	Target Neighborhood Hits	378	Shared Neighborhood Hits	42
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

RSPO4_MOUSE
θ value	3.0926 (rank : 208)	NC score	0.116651 (rank : 169)
Query Neighborhood Hits	246	Target Neighborhood Hits	110	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

FCGRN_HUMAN
θ value	4.03905 (rank : 209)	NC score	0.000043 (rank : 487)
Query Neighborhood Hits	246	Target Neighborhood Hits	177	Shared Neighborhood Hits	3
SwissProt Accessions	P55899, Q9HBV7, Q9NZ19	Gene names	FCGRT, FCRN
Domain Architecture	No domain graphic available
Description	IgG receptor FcRn large subunit p51 precursor (FcRn) (Neonatal Fc receptor) (IgG Fc fragment receptor transporter, alpha chain).

KI13A_MOUSE
θ value	4.03905 (rank : 210)	NC score	0.000168 (rank : 486)
Query Neighborhood Hits	246	Target Neighborhood Hits	395	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EQW7, O35062	Gene names	Kif13a
Domain Architecture
Description	Kinesin-like protein KIF13A.

M3K4_MOUSE
θ value	4.03905 (rank : 211)	NC score	-0.008385 (rank : 498)
Query Neighborhood Hits	246	Target Neighborhood Hits	924	Shared Neighborhood Hits	6
SwissProt Accessions	O08648, O08649, O70124	Gene names	Map3k4, Mekk4
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4).

OR1M1_HUMAN
θ value	4.03905 (rank : 212)	NC score	-0.003677 (rank : 496)
Query Neighborhood Hits	246	Target Neighborhood Hits	831	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NGA1, Q96R91	Gene names	OR1M1
Domain Architecture
Description	Olfactory receptor 1M1 (Olfactory receptor 19-6) (OR19-6).

AZIN1_MOUSE
θ value	5.27518 (rank : 213)	NC score	0.007764 (rank : 474)
Query Neighborhood Hits	246	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	O35484, Q542G5, Q8C2R8, Q8K1E5	Gene names	Azin1, Oazi, Oazin
Domain Architecture
Description	Antizyme inhibitor 1 (AZI) (Ornithine decarboxylase antizyme inhibitor).

FUT4_MOUSE
θ value	5.27518 (rank : 214)	NC score	0.024173 (rank : 460)
Query Neighborhood Hits	246	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q11127	Gene names	Fut4, Elft
Domain Architecture
Description	Alpha-(1,3)-fucosyltransferase (EC 2.4.1.-) (Galactoside 3-L- fucosyltransferase) (Fucosyltransferase 4) (FUCT-IV) (Fuc-TIV).

FZD7_MOUSE
θ value	5.27518 (rank : 215)	NC score	0.036991 (rank : 454)
Query Neighborhood Hits	246	Target Neighborhood Hits	59	Shared Neighborhood Hits	22
SwissProt Accessions	Q61090	Gene names	Fzd7
Domain Architecture	No domain graphic available
Description	Frizzled-7 precursor (Fz-7) (mFz7).

KR412_HUMAN
θ value	5.27518 (rank : 216)	NC score	0.063836 (rank : 342)
Query Neighborhood Hits	246	Target Neighborhood Hits	178	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

OR4D9_HUMAN
θ value	5.27518 (rank : 217)	NC score	-0.002760 (rank : 494)
Query Neighborhood Hits	246	Target Neighborhood Hits	742	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NGE8, Q6IFF3	Gene names	OR4D9
Domain Architecture
Description	Olfactory receptor 4D9 (Olfactory receptor OR11-253).

PTHR2_MOUSE
θ value	5.27518 (rank : 218)	NC score	0.292221 (rank : 148)
Query Neighborhood Hits	246	Target Neighborhood Hits	84	Shared Neighborhood Hits	69
SwissProt Accessions	Q91V95	Gene names	Pthr2
Domain Architecture
Description	Parathyroid hormone receptor precursor (PTH2 receptor).

PTN_HUMAN
θ value	5.27518 (rank : 219)	NC score	0.017828 (rank : 463)
Query Neighborhood Hits	246	Target Neighborhood Hits	7	Shared Neighborhood Hits	5
SwissProt Accessions	P21246	Gene names	PTN, HBNF1, NEGF1
Domain Architecture
Description	Pleiotrophin precursor (PTN) (Heparin-binding growth-associated molecule) (HB-GAM) (Heparin-binding growth factor 8) (HBGF-8) (Osteoblast-specific factor 1) (OSF-1) (Heparin-binding neurite outgrowth-promoting factor 1) (HBNF-1) (Heparin-binding brain mitogen) (HBBM).

SMC4_HUMAN
θ value	5.27518 (rank : 220)	NC score	-0.003262 (rank : 495)
Query Neighborhood Hits	246	Target Neighborhood Hits	937	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

UN13B_HUMAN
θ value	5.27518 (rank : 221)	NC score	0.009532 (rank : 472)
Query Neighborhood Hits	246	Target Neighborhood Hits	217	Shared Neighborhood Hits	7
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

CMTA1_HUMAN
θ value	6.88961 (rank : 222)	NC score	0.010467 (rank : 470)
Query Neighborhood Hits	246	Target Neighborhood Hits	217	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

FZD1_HUMAN
θ value	6.88961 (rank : 223)	NC score	0.042558 (rank : 449)
Query Neighborhood Hits	246	Target Neighborhood Hits	62	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UP38, O94815, Q549T8	Gene names	FZD1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (hFz1) (FzE1).

GNRP_HUMAN
θ value	6.88961 (rank : 224)	NC score	0.002367 (rank : 482)
Query Neighborhood Hits	246	Target Neighborhood Hits	239	Shared Neighborhood Hits	4
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

IGF1R_HUMAN
θ value	6.88961 (rank : 225)	NC score	-0.002429 (rank : 493)
Query Neighborhood Hits	246	Target Neighborhood Hits	977	Shared Neighborhood Hits	39
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

MRC1_HUMAN
θ value	6.88961 (rank : 226)	NC score	0.003568 (rank : 480)
Query Neighborhood Hits	246	Target Neighborhood Hits	157	Shared Neighborhood Hits	8
SwissProt Accessions	P22897	Gene names	MRC1
Domain Architecture
Description	Macrophage mannose receptor 1 precursor (MMR) (CD206 antigen).

PTN_MOUSE
θ value	6.88961 (rank : 227)	NC score	0.015840 (rank : 464)
Query Neighborhood Hits	246	Target Neighborhood Hits	7	Shared Neighborhood Hits	5
SwissProt Accessions	P63089, P20935	Gene names	Ptn
Domain Architecture	No domain graphic available
Description	Pleiotrophin precursor (PTN) (Heparin-binding growth-associated molecule) (HB-GAM) (Heparin-binding growth factor 8) (HBGF-8) (Osteoblast-specific factor 1) (OSF-1) (Heparin-binding neutrophic factor) (HBNF) (Heparin-binding brain mitogen) (HBBM).

TENN_MOUSE
θ value	6.88961 (rank : 228)	NC score	0.024336 (rank : 459)
Query Neighborhood Hits	246	Target Neighborhood Hits	484	Shared Neighborhood Hits	37
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

CRDL2_MOUSE
θ value	8.99809 (rank : 229)	NC score	0.052552 (rank : 417)
Query Neighborhood Hits	246	Target Neighborhood Hits	81	Shared Neighborhood Hits	25
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

EZH2_HUMAN
θ value	8.99809 (rank : 230)	NC score	0.005793 (rank : 476)
Query Neighborhood Hits	246	Target Neighborhood Hits	84	Shared Neighborhood Hits	9
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH2_MOUSE
θ value	8.99809 (rank : 231)	NC score	0.008012 (rank : 473)
Query Neighborhood Hits	246	Target Neighborhood Hits	86	Shared Neighborhood Hits	11
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

FBN1_MOUSE
θ value	8.99809 (rank : 232)	NC score	0.100102 (rank : 196)
Query Neighborhood Hits	246	Target Neighborhood Hits	563	Shared Neighborhood Hits	65
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FZD2_HUMAN
θ value	8.99809 (rank : 233)	NC score	0.035930 (rank : 456)
Query Neighborhood Hits	246	Target Neighborhood Hits	57	Shared Neighborhood Hits	22
SwissProt Accessions	Q14332	Gene names	FZD2
Domain Architecture
Description	Frizzled-2 precursor (Fz-2) (hFz2) (FzE2).

FZD2_MOUSE
θ value	8.99809 (rank : 234)	NC score	0.036174 (rank : 455)
Query Neighborhood Hits	246	Target Neighborhood Hits	60	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JIP6, Q810M0, Q9JIP5, Q9WUJ2	Gene names	Fzd2, Fzd10
Domain Architecture
Description	Frizzled-2 precursor (Fz-2) (mFz2) (mFz10).

HIPK1_MOUSE
θ value	8.99809 (rank : 235)	NC score	-0.008614 (rank : 499)
Query Neighborhood Hits	246	Target Neighborhood Hits	838	Shared Neighborhood Hits	5
SwissProt Accessions	O88904, Q80TV5, Q9QUQ8, Q9QZR3, Q9WVN7	Gene names	Hipk1, Kiaa0630, Myak, Nbak2
Domain Architecture
Description	Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Protein kinase Myak) (Nuclear body-associated kinase 2).

K0776_HUMAN
θ value	8.99809 (rank : 236)	NC score	0.004538 (rank : 477)
Query Neighborhood Hits	246	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	O94874, Q8N765, Q9NTQ0	Gene names	KIAA0776
Domain Architecture	No domain graphic available
Description	Protein KIAA0776.

KRA13_HUMAN
θ value	8.99809 (rank : 237)	NC score	0.040042 (rank : 452)
Query Neighborhood Hits	246	Target Neighborhood Hits	144	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

LYAM2_MOUSE
θ value	8.99809 (rank : 238)	NC score	0.059251 (rank : 370)
Query Neighborhood Hits	246	Target Neighborhood Hits	420	Shared Neighborhood Hits	47
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

MGR4_HUMAN
θ value	8.99809 (rank : 239)	NC score	0.015725 (rank : 465)
Query Neighborhood Hits	246	Target Neighborhood Hits	63	Shared Neighborhood Hits	9
SwissProt Accessions	Q14833, Q5SZ84	Gene names	GRM4, GPRC1D, MGLUR4
Domain Architecture
Description	Metabotropic glutamate receptor 4 precursor (mGluR4).

MRC1_MOUSE
θ value	8.99809 (rank : 240)	NC score	0.002504 (rank : 481)
Query Neighborhood Hits	246	Target Neighborhood Hits	156	Shared Neighborhood Hits	7
SwissProt Accessions	Q61830, Q8C502	Gene names	Mrc1
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 1 precursor (MMR) (CD206 antigen).

RSPO2_HUMAN
θ value	8.99809 (rank : 241)	NC score	0.080213 (rank : 282)
Query Neighborhood Hits	246	Target Neighborhood Hits	90	Shared Neighborhood Hits	39
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

RSPO2_MOUSE
θ value	8.99809 (rank : 242)	NC score	0.073429 (rank : 308)
Query Neighborhood Hits	246	Target Neighborhood Hits	88	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

SMC1A_MOUSE
θ value	8.99809 (rank : 243)	NC score	-0.008033 (rank : 497)
Query Neighborhood Hits	246	Target Neighborhood Hits	1384	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

STAB1_HUMAN
θ value	8.99809 (rank : 244)	NC score	0.097100 (rank : 212)
Query Neighborhood Hits	246	Target Neighborhood Hits	546	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

TENA_HUMAN
θ value	8.99809 (rank : 245)	NC score	0.049025 (rank : 445)
Query Neighborhood Hits	246	Target Neighborhood Hits	631	Shared Neighborhood Hits	57
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

UN13A_HUMAN
θ value	8.99809 (rank : 246)	NC score	0.009670 (rank : 471)
Query Neighborhood Hits	246	Target Neighborhood Hits	285	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

AD26A_MOUSE
θ value	θ > 10 (rank : 247)	NC score	0.067965 (rank : 326)
Query Neighborhood Hits	246	Target Neighborhood Hits	165	Shared Neighborhood Hits	43
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

ADA10_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.050813 (rank : 437)
Query Neighborhood Hits	246	Target Neighborhood Hits	189	Shared Neighborhood Hits	44
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ADA10_MOUSE
θ value	θ > 10 (rank : 249)	NC score	0.050824 (rank : 436)
Query Neighborhood Hits	246	Target Neighborhood Hits	194	Shared Neighborhood Hits	44
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA11_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.057220 (rank : 380)
Query Neighborhood Hits	246	Target Neighborhood Hits	259	Shared Neighborhood Hits	48
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA11_MOUSE
θ value	θ > 10 (rank : 251)	NC score	0.066942 (rank : 331)
Query Neighborhood Hits	246	Target Neighborhood Hits	263	Shared Neighborhood Hits	48
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA12_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.096133 (rank : 225)
Query Neighborhood Hits	246	Target Neighborhood Hits	224	Shared Neighborhood Hits	45
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA12_MOUSE
θ value	θ > 10 (rank : 253)	NC score	0.093340 (rank : 237)
Query Neighborhood Hits	246	Target Neighborhood Hits	474	Shared Neighborhood Hits	45
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA15_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.091315 (rank : 241)
Query Neighborhood Hits	246	Target Neighborhood Hits	288	Shared Neighborhood Hits	56
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

ADA15_MOUSE
θ value	θ > 10 (rank : 255)	NC score	0.079257 (rank : 289)
Query Neighborhood Hits	246	Target Neighborhood Hits	324	Shared Neighborhood Hits	51
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADA17_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.052019 (rank : 424)
Query Neighborhood Hits	246	Target Neighborhood Hits	223	Shared Neighborhood Hits	51
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ADA17_MOUSE
θ value	θ > 10 (rank : 257)	NC score	0.054706 (rank : 393)
Query Neighborhood Hits	246	Target Neighborhood Hits	201	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

ADA18_MOUSE
θ value	θ > 10 (rank : 258)	NC score	0.051384 (rank : 432)
Query Neighborhood Hits	246	Target Neighborhood Hits	227	Shared Neighborhood Hits	51
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ADA19_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.100921 (rank : 188)
Query Neighborhood Hits	246	Target Neighborhood Hits	381	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ADA19_MOUSE
θ value	θ > 10 (rank : 260)	NC score	0.108515 (rank : 178)
Query Neighborhood Hits	246	Target Neighborhood Hits	315	Shared Neighborhood Hits	56
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ADA20_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.052096 (rank : 422)
Query Neighborhood Hits	246	Target Neighborhood Hits	143	Shared Neighborhood Hits	39
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

ADA21_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.068724 (rank : 320)
Query Neighborhood Hits	246	Target Neighborhood Hits	181	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

ADA21_MOUSE
θ value	θ > 10 (rank : 263)	NC score	0.075624 (rank : 303)
Query Neighborhood Hits	246	Target Neighborhood Hits	172	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

ADA22_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.074526 (rank : 306)
Query Neighborhood Hits	246	Target Neighborhood Hits	211	Shared Neighborhood Hits	45
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ADA22_MOUSE
θ value	θ > 10 (rank : 265)	NC score	0.071351 (rank : 313)
Query Neighborhood Hits	246	Target Neighborhood Hits	225	Shared Neighborhood Hits	48
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ADA23_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.069245 (rank : 318)
Query Neighborhood Hits	246	Target Neighborhood Hits	235	Shared Neighborhood Hits	44
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA23_MOUSE
θ value	θ > 10 (rank : 267)	NC score	0.073046 (rank : 310)
Query Neighborhood Hits	246	Target Neighborhood Hits	245	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA24_MOUSE
θ value	θ > 10 (rank : 268)	NC score	0.072963 (rank : 311)
Query Neighborhood Hits	246	Target Neighborhood Hits	230	Shared Neighborhood Hits	52
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ADA25_MOUSE
θ value	θ > 10 (rank : 269)	NC score	0.068137 (rank : 325)
Query Neighborhood Hits	246	Target Neighborhood Hits	213	Shared Neighborhood Hits	37
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

ADA28_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.096735 (rank : 216)
Query Neighborhood Hits	246	Target Neighborhood Hits	244	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ADA28_MOUSE
θ value	θ > 10 (rank : 271)	NC score	0.100648 (rank : 192)
Query Neighborhood Hits	246	Target Neighborhood Hits	241	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ADA29_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.070006 (rank : 317)
Query Neighborhood Hits	246	Target Neighborhood Hits	247	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

ADA32_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.054272 (rank : 398)
Query Neighborhood Hits	246	Target Neighborhood Hits	216	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA32_MOUSE
θ value	θ > 10 (rank : 274)	NC score	0.052815 (rank : 414)
Query Neighborhood Hits	246	Target Neighborhood Hits	219	Shared Neighborhood Hits	44
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA33_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.096196 (rank : 224)
Query Neighborhood Hits	246	Target Neighborhood Hits	264	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA33_MOUSE
θ value	θ > 10 (rank : 276)	NC score	0.087483 (rank : 257)
Query Neighborhood Hits	246	Target Neighborhood Hits	231	Shared Neighborhood Hits	49
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADAM2_MOUSE
θ value	θ > 10 (rank : 277)	NC score	0.059317 (rank : 369)
Query Neighborhood Hits	246	Target Neighborhood Hits	209	Shared Neighborhood Hits	47
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

ADAM7_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.088272 (rank : 255)
Query Neighborhood Hits	246	Target Neighborhood Hits	221	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ADAM7_MOUSE
θ value	θ > 10 (rank : 279)	NC score	0.088991 (rank : 253)
Query Neighborhood Hits	246	Target Neighborhood Hits	200	Shared Neighborhood Hits	45
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADAM8_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.112314 (rank : 174)
Query Neighborhood Hits	246	Target Neighborhood Hits	327	Shared Neighborhood Hits	63
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ADAM8_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.109675 (rank : 176)
Query Neighborhood Hits	246	Target Neighborhood Hits	326	Shared Neighborhood Hits	65
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

ADAM9_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.085781 (rank : 269)
Query Neighborhood Hits	246	Target Neighborhood Hits	243	Shared Neighborhood Hits	47
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

ADAM9_MOUSE
θ value	θ > 10 (rank : 283)	NC score	0.093727 (rank : 234)
Query Neighborhood Hits	246	Target Neighborhood Hits	325	Shared Neighborhood Hits	53
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ADEC1_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.095171 (rank : 227)
Query Neighborhood Hits	246	Target Neighborhood Hits	80	Shared Neighborhood Hits	27
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADEC1_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.077253 (rank : 298)
Query Neighborhood Hits	246	Target Neighborhood Hits	85	Shared Neighborhood Hits	30
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADM1A_MOUSE
θ value	θ > 10 (rank : 286)	NC score	0.076268 (rank : 302)
Query Neighborhood Hits	246	Target Neighborhood Hits	230	Shared Neighborhood Hits	56
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ADM1B_MOUSE
θ value	θ > 10 (rank : 287)	NC score	0.078107 (rank : 294)
Query Neighborhood Hits	246	Target Neighborhood Hits	236	Shared Neighborhood Hits	52
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

AGRIN_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.079715 (rank : 286)
Query Neighborhood Hits	246	Target Neighborhood Hits	582	Shared Neighborhood Hits	57
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

BMPER_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.055876 (rank : 386)
Query Neighborhood Hits	246	Target Neighborhood Hits	175	Shared Neighborhood Hits	33
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

BMPER_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.052955 (rank : 412)
Query Neighborhood Hits	246	Target Neighborhood Hits	194	Shared Neighborhood Hits	37
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

C1QR1_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.107184 (rank : 182)
Query Neighborhood Hits	246	Target Neighborhood Hits	493	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.107834 (rank : 181)
Query Neighborhood Hits	246	Target Neighborhood Hits	342	Shared Neighborhood Hits	44
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

CAD16_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.054220 (rank : 401)
Query Neighborhood Hits	246	Target Neighborhood Hits	159	Shared Neighborhood Hits	6
SwissProt Accessions	O75309, Q6UW93	Gene names	CDH16
Domain Architecture
Description	Cadherin-16 precursor (Kidney-specific cadherin) (Ksp-cadherin).

CAD16_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.054236 (rank : 400)
Query Neighborhood Hits	246	Target Neighborhood Hits	170	Shared Neighborhood Hits	8
SwissProt Accessions	O88338, Q9JLZ5	Gene names	Cdh16
Domain Architecture
Description	Cadherin-16 precursor (Kidney-specific cadherin) (Ksp-cadherin).

CAD17_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.056009 (rank : 385)
Query Neighborhood Hits	246	Target Neighborhood Hits	154	Shared Neighborhood Hits	6
SwissProt Accessions	Q12864, Q15336	Gene names	CDH17
Domain Architecture
Description	Cadherin-17 precursor (Liver-intestine-cadherin) (LI-cadherin) (Intestinal peptide-associated transporter HPT-1).

CAD17_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.057960 (rank : 376)
Query Neighborhood Hits	246	Target Neighborhood Hits	157	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R100	Gene names	Cdh17
Domain Architecture
Description	Cadherin-17 precursor (Liver-intestine-cadherin) (LI-cadherin) (BILL- cadherin) (P130).

CAD23_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.066211 (rank : 334)
Query Neighborhood Hits	246	Target Neighborhood Hits	197	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H251, Q6UWW1, Q9H4K9	Gene names	CDH23, KIAA1774
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

CAD23_MOUSE
θ value	θ > 10 (rank : 298)	NC score	0.066533 (rank : 332)
Query Neighborhood Hits	246	Target Neighborhood Hits	208	Shared Neighborhood Hits	11
SwissProt Accessions	Q99PF4, Q99NH1, Q9D4N9	Gene names	Cdh23
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

CD248_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.051778 (rank : 427)
Query Neighborhood Hits	246	Target Neighborhood Hits	679	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD248_MOUSE
θ value	θ > 10 (rank : 300)	NC score	0.059016 (rank : 371)
Query Neighborhood Hits	246	Target Neighborhood Hits	578	Shared Neighborhood Hits	31
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CO9_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.081378 (rank : 279)
Query Neighborhood Hits	246	Target Neighborhood Hits	147	Shared Neighborhood Hits	24
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

CO9_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.095268 (rank : 226)
Query Neighborhood Hits	246	Target Neighborhood Hits	153	Shared Neighborhood Hits	32
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

COMP_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.149301 (rank : 157)
Query Neighborhood Hits	246	Target Neighborhood Hits	258	Shared Neighborhood Hits	32
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

COMP_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.154348 (rank : 154)
Query Neighborhood Hits	246	Target Neighborhood Hits	290	Shared Neighborhood Hits	32
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CREL1_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.096691 (rank : 218)
Query Neighborhood Hits	246	Target Neighborhood Hits	441	Shared Neighborhood Hits	43
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.094099 (rank : 231)
Query Neighborhood Hits	246	Target Neighborhood Hits	524	Shared Neighborhood Hits	45
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CRIM1_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.068363 (rank : 323)
Query Neighborhood Hits	246	Target Neighborhood Hits	362	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

CRUM1_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.116286 (rank : 170)
Query Neighborhood Hits	246	Target Neighborhood Hits	457	Shared Neighborhood Hits	58
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM1_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.114942 (rank : 172)
Query Neighborhood Hits	246	Target Neighborhood Hits	444	Shared Neighborhood Hits	56
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CRUM2_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.108154 (rank : 179)
Query Neighborhood Hits	246	Target Neighborhood Hits	453	Shared Neighborhood Hits	54
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

CSPG2_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.059512 (rank : 367)
Query Neighborhood Hits	246	Target Neighborhood Hits	681	Shared Neighborhood Hits	44
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CSPG2_MOUSE
θ value	θ > 10 (rank : 312)	NC score	0.062147 (rank : 354)
Query Neighborhood Hits	246	Target Neighborhood Hits	711	Shared Neighborhood Hits	45
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CSPG3_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.061627 (rank : 357)
Query Neighborhood Hits	246	Target Neighborhood Hits	676	Shared Neighborhood Hits	40
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CSPG3_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.063910 (rank : 341)
Query Neighborhood Hits	246	Target Neighborhood Hits	657	Shared Neighborhood Hits	38
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CTGF_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.060451 (rank : 362)
Query Neighborhood Hits	246	Target Neighborhood Hits	128	Shared Neighborhood Hits	44
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

CTGF_MOUSE
θ value	θ > 10 (rank : 316)	NC score	0.061618 (rank : 358)
Query Neighborhood Hits	246	Target Neighborhood Hits	124	Shared Neighborhood Hits	45
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

CU063_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.052115 (rank : 421)
Query Neighborhood Hits	246	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	P58658, Q8IXZ0	Gene names	C21orf63
Domain Architecture
Description	Protein C21orf63 precursor (SUE21).

CU063_MOUSE
θ value	θ > 10 (rank : 318)	NC score	0.050271 (rank : 441)
Query Neighborhood Hits	246	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	P58659	Gene names
Domain Architecture
Description	Protein C21orf63 homolog precursor.

CUBN_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.088685 (rank : 254)
Query Neighborhood Hits	246	Target Neighborhood Hits	482	Shared Neighborhood Hits	50
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

DLK_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.087419 (rank : 258)
Query Neighborhood Hits	246	Target Neighborhood Hits	401	Shared Neighborhood Hits	48
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLK_MOUSE
θ value	θ > 10 (rank : 321)	NC score	0.086401 (rank : 263)
Query Neighborhood Hits	246	Target Neighborhood Hits	374	Shared Neighborhood Hits	50
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

DLL1_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.098946 (rank : 201)
Query Neighborhood Hits	246	Target Neighborhood Hits	455	Shared Neighborhood Hits	60
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DLL1_MOUSE
θ value	θ > 10 (rank : 323)	NC score	0.097502 (rank : 208)
Query Neighborhood Hits	246	Target Neighborhood Hits	456	Shared Neighborhood Hits	60
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

DLL3_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.080424 (rank : 281)
Query Neighborhood Hits	246	Target Neighborhood Hits	419	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DLL3_MOUSE
θ value	θ > 10 (rank : 325)	NC score	0.083601 (rank : 275)
Query Neighborhood Hits	246	Target Neighborhood Hits	399	Shared Neighborhood Hits	50
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

DLL4_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.092192 (rank : 240)
Query Neighborhood Hits	246	Target Neighborhood Hits	435	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL4_MOUSE
θ value	θ > 10 (rank : 327)	NC score	0.089268 (rank : 252)
Query Neighborhood Hits	246	Target Neighborhood Hits	440	Shared Neighborhood Hits	61
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DNER_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.092790 (rank : 239)
Query Neighborhood Hits	246	Target Neighborhood Hits	460	Shared Neighborhood Hits	58
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DNER_MOUSE
θ value	θ > 10 (rank : 329)	NC score	0.089302 (rank : 251)
Query Neighborhood Hits	246	Target Neighborhood Hits	413	Shared Neighborhood Hits	59
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

EDIL3_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.062853 (rank : 349)
Query Neighborhood Hits	246	Target Neighborhood Hits	292	Shared Neighborhood Hits	31
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.062464 (rank : 351)
Query Neighborhood Hits	246	Target Neighborhood Hits	317	Shared Neighborhood Hits	31
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EGFL7_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.079821 (rank : 285)
Query Neighborhood Hits	246	Target Neighborhood Hits	325	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL7_MOUSE
θ value	θ > 10 (rank : 333)	NC score	0.068595 (rank : 321)
Query Neighborhood Hits	246	Target Neighborhood Hits	287	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EGFL8_MOUSE
θ value	θ > 10 (rank : 334)	NC score	0.055848 (rank : 387)
Query Neighborhood Hits	246	Target Neighborhood Hits	266	Shared Neighborhood Hits	24
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EGFL9_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.077023 (rank : 301)
Query Neighborhood Hits	246	Target Neighborhood Hits	365	Shared Neighborhood Hits	48
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
θ value	θ > 10 (rank : 336)	NC score	0.079016 (rank : 291)
Query Neighborhood Hits	246	Target Neighborhood Hits	379	Shared Neighborhood Hits	47
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

EGF_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.097440 (rank : 209)
Query Neighborhood Hits	246	Target Neighborhood Hits	343	Shared Neighborhood Hits	42
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EGF_MOUSE
θ value	θ > 10 (rank : 338)	NC score	0.094612 (rank : 228)
Query Neighborhood Hits	246	Target Neighborhood Hits	358	Shared Neighborhood Hits	42
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

FAT2_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.067918 (rank : 327)
Query Neighborhood Hits	246	Target Neighborhood Hits	507	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

FATH_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.082997 (rank : 277)
Query Neighborhood Hits	246	Target Neighborhood Hits	570	Shared Neighborhood Hits	44
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

FBLN1_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.100706 (rank : 191)
Query Neighborhood Hits	246	Target Neighborhood Hits	324	Shared Neighborhood Hits	45
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN1_MOUSE
θ value	θ > 10 (rank : 342)	NC score	0.098204 (rank : 205)
Query Neighborhood Hits	246	Target Neighborhood Hits	329	Shared Neighborhood Hits	44
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN2_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.091001 (rank : 243)
Query Neighborhood Hits	246	Target Neighborhood Hits	392	Shared Neighborhood Hits	48
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_MOUSE
θ value	θ > 10 (rank : 344)	NC score	0.093601 (rank : 235)
Query Neighborhood Hits	246	Target Neighborhood Hits	505	Shared Neighborhood Hits	53
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN3_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.100804 (rank : 189)
Query Neighborhood Hits	246	Target Neighborhood Hits	293	Shared Neighborhood Hits	41
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN3_MOUSE
θ value	θ > 10 (rank : 346)	NC score	0.097999 (rank : 206)
Query Neighborhood Hits	246	Target Neighborhood Hits	279	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN4_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.108041 (rank : 180)
Query Neighborhood Hits	246	Target Neighborhood Hits	278	Shared Neighborhood Hits	43
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.109092 (rank : 177)
Query Neighborhood Hits	246	Target Neighborhood Hits	270	Shared Neighborhood Hits	41
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.099818 (rank : 197)
Query Neighborhood Hits	246	Target Neighborhood Hits	329	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
θ value	θ > 10 (rank : 350)	NC score	0.096892 (rank : 215)
Query Neighborhood Hits	246	Target Neighborhood Hits	317	Shared Neighborhood Hits	47
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBN2_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.097747 (rank : 207)
Query Neighborhood Hits	246	Target Neighborhood Hits	560	Shared Neighborhood Hits	68
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.097335 (rank : 210)
Query Neighborhood Hits	246	Target Neighborhood Hits	549	Shared Neighborhood Hits	69
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.096717 (rank : 217)
Query Neighborhood Hits	246	Target Neighborhood Hits	543	Shared Neighborhood Hits	58
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

GAS6_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.086815 (rank : 261)
Query Neighborhood Hits	246	Target Neighborhood Hits	348	Shared Neighborhood Hits	38
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GAS6_MOUSE
θ value	θ > 10 (rank : 355)	NC score	0.087038 (rank : 259)
Query Neighborhood Hits	246	Target Neighborhood Hits	343	Shared Neighborhood Hits	39
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GP155_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.050710 (rank : 438)
Query Neighborhood Hits	246	Target Neighborhood Hits	42	Shared Neighborhood Hits	20
SwissProt Accessions	Q7Z3F1, Q53SJ3, Q53TA8, Q69YG8, Q86SP9, Q8N261, Q8N639, Q8N8K3, Q96MV6	Gene names	GPR155, PGR22
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR155 (G-protein coupled receptor PGR22).

GP157_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.225175 (rank : 149)
Query Neighborhood Hits	246	Target Neighborhood Hits	93	Shared Neighborhood Hits	56
SwissProt Accessions	Q5UAW9, Q8WWB8, Q9HA73	Gene names	GPR157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

GP157_MOUSE
θ value	θ > 10 (rank : 358)	NC score	0.218265 (rank : 150)
Query Neighborhood Hits	246	Target Neighborhood Hits	78	Shared Neighborhood Hits	56
SwissProt Accessions	Q8C206, Q8C224	Gene names	Gpr157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

JAG1_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.090700 (rank : 244)
Query Neighborhood Hits	246	Target Neighborhood Hits	514	Shared Neighborhood Hits	61
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
θ value	θ > 10 (rank : 360)	NC score	0.090471 (rank : 247)
Query Neighborhood Hits	246	Target Neighborhood Hits	518	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG2_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.087896 (rank : 256)
Query Neighborhood Hits	246	Target Neighborhood Hits	491	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG2_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.085523 (rank : 271)
Query Neighborhood Hits	246	Target Neighborhood Hits	504	Shared Neighborhood Hits	61
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

KR104_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.077142 (rank : 299)
Query Neighborhood Hits	246	Target Neighborhood Hits	313	Shared Neighborhood Hits	49
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR105_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.056908 (rank : 381)
Query Neighborhood Hits	246	Target Neighborhood Hits	271	Shared Neighborhood Hits	42
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR107_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.075579 (rank : 304)
Query Neighborhood Hits	246	Target Neighborhood Hits	330	Shared Neighborhood Hits	48
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR108_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.051195 (rank : 434)
Query Neighborhood Hits	246	Target Neighborhood Hits	226	Shared Neighborhood Hits	34
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR109_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.063716 (rank : 343)
Query Neighborhood Hits	246	Target Neighborhood Hits	226	Shared Neighborhood Hits	40
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KRA51_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.061913 (rank : 356)
Query Neighborhood Hits	246	Target Neighborhood Hits	288	Shared Neighborhood Hits	42
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA92_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.054251 (rank : 399)
Query Neighborhood Hits	246	Target Neighborhood Hits	198	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA98_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.051235 (rank : 433)
Query Neighborhood Hits	246	Target Neighborhood Hits	185	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

LAMA5_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.055215 (rank : 392)
Query Neighborhood Hits	246	Target Neighborhood Hits	976	Shared Neighborhood Hits	64
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMA5_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.055419 (rank : 390)
Query Neighborhood Hits	246	Target Neighborhood Hits	828	Shared Neighborhood Hits	60
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB2_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.054416 (rank : 397)
Query Neighborhood Hits	246	Target Neighborhood Hits	692	Shared Neighborhood Hits	46
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMC3_MOUSE
θ value	θ > 10 (rank : 374)	NC score	0.055677 (rank : 388)
Query Neighborhood Hits	246	Target Neighborhood Hits	624	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LDLR_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.067161 (rank : 328)
Query Neighborhood Hits	246	Target Neighborhood Hits	375	Shared Neighborhood Hits	50
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP1B_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.077039 (rank : 300)
Query Neighborhood Hits	246	Target Neighborhood Hits	602	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1B_MOUSE
θ value	θ > 10 (rank : 377)	NC score	0.075395 (rank : 305)
Query Neighborhood Hits	246	Target Neighborhood Hits	606	Shared Neighborhood Hits	68
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.079926 (rank : 283)
Query Neighborhood Hits	246	Target Neighborhood Hits	617	Shared Neighborhood Hits	73
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP2_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.079502 (rank : 288)
Query Neighborhood Hits	246	Target Neighborhood Hits	573	Shared Neighborhood Hits	67
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LRP8_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.061039 (rank : 361)
Query Neighborhood Hits	246	Target Neighborhood Hits	346	Shared Neighborhood Hits	45
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP8_MOUSE
θ value	θ > 10 (rank : 381)	NC score	0.063621 (rank : 345)
Query Neighborhood Hits	246	Target Neighborhood Hits	385	Shared Neighborhood Hits	50
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LTB1L_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.096200 (rank : 223)
Query Neighborhood Hits	246	Target Neighborhood Hits	553	Shared Neighborhood Hits	58
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_MOUSE
θ value	θ > 10 (rank : 383)	NC score	0.094141 (rank : 230)
Query Neighborhood Hits	246	Target Neighborhood Hits	514	Shared Neighborhood Hits	62
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.094099 (rank : 232)
Query Neighborhood Hits	246	Target Neighborhood Hits	502	Shared Neighborhood Hits	49
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	θ > 10 (rank : 385)	NC score	0.092847 (rank : 238)
Query Neighborhood Hits	246	Target Neighborhood Hits	479	Shared Neighborhood Hits	54
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP2_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.098525 (rank : 203)
Query Neighborhood Hits	246	Target Neighborhood Hits	552	Shared Neighborhood Hits	61
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP2_MOUSE
θ value	θ > 10 (rank : 387)	NC score	0.098672 (rank : 202)
Query Neighborhood Hits	246	Target Neighborhood Hits	617	Shared Neighborhood Hits	63
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP3_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.096691 (rank : 219)
Query Neighborhood Hits	246	Target Neighborhood Hits	502	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP3_MOUSE
θ value	θ > 10 (rank : 389)	NC score	0.093416 (rank : 236)
Query Neighborhood Hits	246	Target Neighborhood Hits	475	Shared Neighborhood Hits	54
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP4_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.104286 (rank : 186)
Query Neighborhood Hits	246	Target Neighborhood Hits	607	Shared Neighborhood Hits	62
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

LYAM3_MOUSE
θ value	θ > 10 (rank : 391)	NC score	0.053067 (rank : 411)
Query Neighborhood Hits	246	Target Neighborhood Hits	390	Shared Neighborhood Hits	43
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MATN2_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.068364 (rank : 322)
Query Neighborhood Hits	246	Target Neighborhood Hits	365	Shared Neighborhood Hits	40
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

MATN2_MOUSE
θ value	θ > 10 (rank : 393)	NC score	0.062806 (rank : 350)
Query Neighborhood Hits	246	Target Neighborhood Hits	356	Shared Neighborhood Hits	37
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MATN3_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.059459 (rank : 368)
Query Neighborhood Hits	246	Target Neighborhood Hits	268	Shared Neighborhood Hits	27
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_MOUSE
θ value	θ > 10 (rank : 395)	NC score	0.060052 (rank : 366)
Query Neighborhood Hits	246	Target Neighborhood Hits	261	Shared Neighborhood Hits	29
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.064213 (rank : 339)
Query Neighborhood Hits	246	Target Neighborhood Hits	287	Shared Neighborhood Hits	32
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MEGF6_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.104526 (rank : 184)
Query Neighborhood Hits	246	Target Neighborhood Hits	671	Shared Neighborhood Hits	85
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

MEGF8_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.077474 (rank : 297)
Query Neighborhood Hits	246	Target Neighborhood Hits	528	Shared Neighborhood Hits	53
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_MOUSE
θ value	θ > 10 (rank : 399)	NC score	0.074294 (rank : 307)
Query Neighborhood Hits	246	Target Neighborhood Hits	520	Shared Neighborhood Hits	51
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF9_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.060223 (rank : 365)
Query Neighborhood Hits	246	Target Neighborhood Hits	557	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MUC2_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.050084 (rank : 442)
Query Neighborhood Hits	246	Target Neighborhood Hits	906	Shared Neighborhood Hits	38
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MUC5B_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.062067 (rank : 355)
Query Neighborhood Hits	246	Target Neighborhood Hits	1020	Shared Neighborhood Hits	58
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MUCDL_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.052468 (rank : 419)
Query Neighborhood Hits	246	Target Neighborhood Hits	777	Shared Neighborhood Hits	14
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MYOC_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.056786 (rank : 382)
Query Neighborhood Hits	246	Target Neighborhood Hits	489	Shared Neighborhood Hits	5
SwissProt Accessions	Q99972, O00620, Q7Z6Q9	Gene names	MYOC, GLC1A, TIGR
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

MYOC_MOUSE
θ value	θ > 10 (rank : 405)	NC score	0.066488 (rank : 333)
Query Neighborhood Hits	246	Target Neighborhood Hits	232	Shared Neighborhood Hits	4
SwissProt Accessions	O70624, O70289	Gene names	Myoc, Tigr
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

NELL1_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.130294 (rank : 161)
Query Neighborhood Hits	246	Target Neighborhood Hits	451	Shared Neighborhood Hits	57
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NELL2_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.124129 (rank : 166)
Query Neighborhood Hits	246	Target Neighborhood Hits	449	Shared Neighborhood Hits	49
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
θ value	θ > 10 (rank : 408)	NC score	0.127662 (rank : 162)
Query Neighborhood Hits	246	Target Neighborhood Hits	436	Shared Neighborhood Hits	49
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NID1_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.100213 (rank : 194)
Query Neighborhood Hits	246	Target Neighborhood Hits	329	Shared Neighborhood Hits	42
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_MOUSE
θ value	θ > 10 (rank : 410)	NC score	0.096988 (rank : 213)
Query Neighborhood Hits	246	Target Neighborhood Hits	335	Shared Neighborhood Hits	40
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.097261 (rank : 211)
Query Neighborhood Hits	246	Target Neighborhood Hits	456	Shared Neighborhood Hits	47
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID2_MOUSE
θ value	θ > 10 (rank : 412)	NC score	0.096680 (rank : 220)
Query Neighborhood Hits	246	Target Neighborhood Hits	338	Shared Neighborhood Hits	42
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NOE1_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.058123 (rank : 374)
Query Neighborhood Hits	246	Target Neighborhood Hits	266	Shared Neighborhood Hits	6
SwissProt Accessions	Q99784, Q969S7, Q99452	Gene names	OLFM1, NOE1, NOEL1
Domain Architecture
Description	Noelin precursor (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1).

NOE1_MOUSE
θ value	θ > 10 (rank : 414)	NC score	0.058714 (rank : 372)
Query Neighborhood Hits	246	Target Neighborhood Hits	258	Shared Neighborhood Hits	6
SwissProt Accessions	O88998, O35429, O88999, Q91XK8, Q9QWQ9, Q9QWR0	Gene names	Olfm1, Noe1, Noel, Noel1
Domain Architecture
Description	Noelin precursor (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1) (Pancortin).

NOE2_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.062216 (rank : 352)
Query Neighborhood Hits	246	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	O95897, Q6IMJ3, Q96FC2	Gene names	OLFM2, NOE2
Domain Architecture
Description	Noelin-2 precursor (Olfactomedin-2).

NOE2_MOUSE
θ value	θ > 10 (rank : 416)	NC score	0.062183 (rank : 353)
Query Neighborhood Hits	246	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BM13	Gene names	Olfm2
Domain Architecture	No domain graphic available
Description	Noelin-2 precursor (Olfactomedin-2).

NOE3_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.060384 (rank : 363)
Query Neighborhood Hits	246	Target Neighborhood Hits	109	Shared Neighborhood Hits	3
SwissProt Accessions	Q96PB7, Q8TBG1, Q96PB2, Q96PB3, Q96PB4, Q96PB5, Q96PB6	Gene names	OLFM3, NOE3
Domain Architecture
Description	Noelin-3 precursor (Olfactomedin-3) (Optimedin).

NOE3_MOUSE
θ value	θ > 10 (rank : 418)	NC score	0.060256 (rank : 364)
Query Neighborhood Hits	246	Target Neighborhood Hits	116	Shared Neighborhood Hits	3
SwissProt Accessions	P63056, Q8BKV2, Q8BLL6, Q8QZW0, Q8R4K3, Q8R4K4	Gene names	Olfm3, Noe3
Domain Architecture	No domain graphic available
Description	Noelin-3 precursor (Olfactomedin-3) (Optimedin).

NOTC1_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.085998 (rank : 266)
Query Neighborhood Hits	246	Target Neighborhood Hits	906	Shared Neighborhood Hits	80
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC1_MOUSE
θ value	θ > 10 (rank : 420)	NC score	0.086122 (rank : 265)
Query Neighborhood Hits	246	Target Neighborhood Hits	916	Shared Neighborhood Hits	71
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.086210 (rank : 264)
Query Neighborhood Hits	246	Target Neighborhood Hits	1113	Shared Neighborhood Hits	76
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
θ value	θ > 10 (rank : 422)	NC score	0.084277 (rank : 273)
Query Neighborhood Hits	246	Target Neighborhood Hits	1069	Shared Neighborhood Hits	69
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC3_HUMAN
θ value	θ > 10 (rank : 423)	NC score	0.090554 (rank : 246)
Query Neighborhood Hits	246	Target Neighborhood Hits	1062	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
θ value	θ > 10 (rank : 424)	NC score	0.091169 (rank : 242)
Query Neighborhood Hits	246	Target Neighborhood Hits	975	Shared Neighborhood Hits	81
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC4_HUMAN
θ value	θ > 10 (rank : 425)	NC score	0.086879 (rank : 260)
Query Neighborhood Hits	246	Target Neighborhood Hits	905	Shared Neighborhood Hits	71
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC4_MOUSE
θ value	θ > 10 (rank : 426)	NC score	0.085757 (rank : 270)
Query Neighborhood Hits	246	Target Neighborhood Hits	872	Shared Neighborhood Hits	69
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOV_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.084397 (rank : 272)
Query Neighborhood Hits	246	Target Neighborhood Hits	128	Shared Neighborhood Hits	47
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

NOV_MOUSE
θ value	θ > 10 (rank : 428)	NC score	0.083827 (rank : 274)
Query Neighborhood Hits	246	Target Neighborhood Hits	130	Shared Neighborhood Hits	49
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

NRX1A_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.053327 (rank : 408)
Query Neighborhood Hits	246	Target Neighborhood Hits	170	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
θ value	θ > 10 (rank : 430)	NC score	0.053202 (rank : 409)
Query Neighborhood Hits	246	Target Neighborhood Hits	164	Shared Neighborhood Hits	17
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX2A_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.058180 (rank : 373)
Query Neighborhood Hits	246	Target Neighborhood Hits	614	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX3A_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.055326 (rank : 391)
Query Neighborhood Hits	246	Target Neighborhood Hits	164	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

OLFL1_HUMAN
θ value	θ > 10 (rank : 433)	NC score	0.064967 (rank : 338)
Query Neighborhood Hits	246	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q6UWY5	Gene names	OLFML1
Domain Architecture	No domain graphic available
Description	Olfactomedin-like protein 1 precursor.

OLFL3_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.061603 (rank : 359)
Query Neighborhood Hits	246	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRN5, Q53FR1, Q53HV9, Q5SQL6, Q69AX9, Q8NBJ2	Gene names	OLFML3
Domain Architecture
Description	Olfactomedin-like protein 3 precursor (HNOEL-iso) (hOLF44).

OLFL3_MOUSE
θ value	θ > 10 (rank : 435)	NC score	0.061566 (rank : 360)
Query Neighborhood Hits	246	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BK62, Q3V2F2, Q8C1T0, Q99K37	Gene names	Olfml3
Domain Architecture	No domain graphic available
Description	Olfactomedin-like protein 3 precursor.

PC11X_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.053902 (rank : 403)
Query Neighborhood Hits	246	Target Neighborhood Hits	199	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BZA7, Q2TJH0, Q2TJH1, Q2TJH3, Q5JVZ0, Q70LR8, Q70LS7, Q70LS8, Q70LS9, Q70LT7, Q70LT8, Q70LT9, Q70LU0, Q70LU1, Q96RV4, Q96RW0, Q9BZA6, Q9H4E0, Q9P2M0, Q9P2X5	Gene names	PCDH11X, PCDH11, PCDHX
Domain Architecture	No domain graphic available
Description	Protocadherin-11 X-linked precursor (Protocadherin-11) (Protocadherin on the X chromosome) (PCDH-X) (Protocadherin-S).

PC11Y_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.054076 (rank : 402)
Query Neighborhood Hits	246	Target Neighborhood Hits	205	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BZA8, Q70LR6, Q70LR8, Q70LS0, Q70LS1, Q70LS2, Q70LS3, Q70LS4, Q70LS5, Q8WY34, Q9BZA9, Q9H4E1	Gene names	PCDH11Y, PCDH11, PCDH22, PCDHY
Domain Architecture	No domain graphic available
Description	Protocadherin-11 Y-linked precursor (Protocadherin-11) (Protocadherin- 22) (Protocadherin on the Y chromosome) (PCDH-Y) (Protocadherin prostate cancer) (Protocadherin-PC).

PCD15_HUMAN
θ value	θ > 10 (rank : 438)	NC score	0.065699 (rank : 336)
Query Neighborhood Hits	246	Target Neighborhood Hits	289	Shared Neighborhood Hits	7
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

PCD15_MOUSE
θ value	θ > 10 (rank : 439)	NC score	0.065842 (rank : 335)
Query Neighborhood Hits	246	Target Neighborhood Hits	262	Shared Neighborhood Hits	8
SwissProt Accessions	Q99PJ1	Gene names	Pcdh15
Domain Architecture
Description	Protocadherin-15 precursor.

PCD16_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.063506 (rank : 346)
Query Neighborhood Hits	246	Target Neighborhood Hits	245	Shared Neighborhood Hits	8
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

PCD20_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.054584 (rank : 394)
Query Neighborhood Hits	246	Target Neighborhood Hits	153	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N6Y1, Q8NDN4, Q9NRT9	Gene names	PCDH20
Domain Architecture	No domain graphic available
Description	Protocadherin-20 precursor (Protocadherin-13).

PCD20_MOUSE
θ value	θ > 10 (rank : 442)	NC score	0.054529 (rank : 396)
Query Neighborhood Hits	246	Target Neighborhood Hits	150	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BIZ0, Q8BIV2	Gene names	Pcdh20
Domain Architecture	No domain graphic available
Description	Protocadherin-20 precursor.

PCDH1_HUMAN
θ value	θ > 10 (rank : 443)	NC score	0.056403 (rank : 383)
Query Neighborhood Hits	246	Target Neighborhood Hits	174	Shared Neighborhood Hits	6
SwissProt Accessions	Q08174	Gene names	PCDH1
Domain Architecture
Description	Protocadherin-1 precursor (Protocadherin-42) (PC42) (Cadherin-like protein 1).

PCDH7_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.055430 (rank : 389)
Query Neighborhood Hits	246	Target Neighborhood Hits	175	Shared Neighborhood Hits	6
SwissProt Accessions	O60245, O60246, O60247	Gene names	PCDH7, BHPCDH
Domain Architecture
Description	Protocadherin-7 precursor (Brain-heart protocadherin) (BH-Pcdh).

PCDH9_HUMAN
θ value	θ > 10 (rank : 445)	NC score	0.054582 (rank : 395)
Query Neighborhood Hits	246	Target Neighborhood Hits	180	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HC56	Gene names	PCDH9
Domain Architecture
Description	Protocadherin-9 precursor.

PCDLK_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.063437 (rank : 347)
Query Neighborhood Hits	246	Target Neighborhood Hits	172	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYE9, Q9NXP8	Gene names	PCLKC
Domain Architecture	No domain graphic available
Description	Protocadherin LKC precursor (PC-LKC).

PGBM_HUMAN
θ value	θ > 10 (rank : 447)	NC score	0.067144 (rank : 330)
Query Neighborhood Hits	246	Target Neighborhood Hits	1113	Shared Neighborhood Hits	62
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGBM_MOUSE
θ value	θ > 10 (rank : 448)	NC score	0.067161 (rank : 329)
Query Neighborhood Hits	246	Target Neighborhood Hits	1073	Shared Neighborhood Hits	64
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PROS_HUMAN
θ value	θ > 10 (rank : 449)	NC score	0.094414 (rank : 229)
Query Neighborhood Hits	246	Target Neighborhood Hits	340	Shared Neighborhood Hits	35
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
θ value	θ > 10 (rank : 450)	NC score	0.094057 (rank : 233)
Query Neighborhood Hits	246	Target Neighborhood Hits	330	Shared Neighborhood Hits	41
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROZ_HUMAN
θ value	θ > 10 (rank : 451)	NC score	0.053183 (rank : 410)
Query Neighborhood Hits	246	Target Neighborhood Hits	422	Shared Neighborhood Hits	31
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_MOUSE
θ value	θ > 10 (rank : 452)	NC score	0.052755 (rank : 416)
Query Neighborhood Hits	246	Target Neighborhood Hits	410	Shared Neighborhood Hits	29
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

ROBO4_MOUSE
θ value	θ > 10 (rank : 453)	NC score	0.052518 (rank : 418)
Query Neighborhood Hits	246	Target Neighborhood Hits	358	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

SCUB3_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.090581 (rank : 245)
Query Neighborhood Hits	246	Target Neighborhood Hits	428	Shared Neighborhood Hits	47
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
θ value	θ > 10 (rank : 455)	NC score	0.090270 (rank : 249)
Query Neighborhood Hits	246	Target Neighborhood Hits	442	Shared Neighborhood Hits	49
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SEM3C_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.051684 (rank : 428)
Query Neighborhood Hits	246	Target Neighborhood Hits	106	Shared Neighborhood Hits	9
SwissProt Accessions	Q99985	Gene names	SEMA3C, SEMAE
Domain Architecture
Description	Semaphorin-3C precursor (Semaphorin E) (Sema E).

SEM3C_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.051616 (rank : 430)
Query Neighborhood Hits	246	Target Neighborhood Hits	113	Shared Neighborhood Hits	10
SwissProt Accessions	Q62181	Gene names	Sema3c, Semae, SemE
Domain Architecture
Description	Semaphorin-3C precursor (Semaphorin E) (Sema E).

SEM3F_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.051026 (rank : 435)
Query Neighborhood Hits	246	Target Neighborhood Hits	100	Shared Neighborhood Hits	12
SwissProt Accessions	Q13275, Q13274, Q13372, Q15704	Gene names	SEMA3F
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV) (Sema III/F).

SEM4A_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.050602 (rank : 439)
Query Neighborhood Hits	246	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H3S1, Q8WUA9	Gene names	SEMA4A, SEMB
Domain Architecture
Description	Semaphorin-4A precursor (Semaphorin B) (Sema B).

SEM4A_MOUSE
θ value	θ > 10 (rank : 460)	NC score	0.050036 (rank : 443)
Query Neighborhood Hits	246	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	Q62178	Gene names	Sema4a, Semab, SemB
Domain Architecture
Description	Semaphorin-4A precursor (Semaphorin B) (Sema B).

SEM4C_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.052081 (rank : 423)
Query Neighborhood Hits	246	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q9C0C4, Q7Z5X0	Gene names	SEMA4C, KIAA1739
Domain Architecture
Description	Semaphorin-4C precursor.

SEM4C_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.050271 (rank : 440)
Query Neighborhood Hits	246	Target Neighborhood Hits	77	Shared Neighborhood Hits	5
SwissProt Accessions	Q64151	Gene names	Sema4c, Semacl1, Semai
Domain Architecture
Description	Semaphorin-4C precursor (Semaphorin I) (Sema I) (Semaphorin C-like 1) (M-Sema F).

SEM6A_HUMAN
θ value	θ > 10 (rank : 463)	NC score	0.051885 (rank : 426)
Query Neighborhood Hits	246	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H2E6, Q9P2H9	Gene names	SEMA6A, KIAA1368
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1).

SEM6A_MOUSE
θ value	θ > 10 (rank : 464)	NC score	0.052236 (rank : 420)
Query Neighborhood Hits	246	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	O35464, Q6P5A8, Q6PCN9, Q9EQ71	Gene names	Sema6a, Semaq
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1) (Semaphorin Q) (Sema Q).

SEM6B_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.053831 (rank : 404)
Query Neighborhood Hits	246	Target Neighborhood Hits	187	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

SEM6B_MOUSE
θ value	θ > 10 (rank : 466)	NC score	0.053491 (rank : 407)
Query Neighborhood Hits	246	Target Neighborhood Hits	200	Shared Neighborhood Hits	4
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

SEM6C_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.053649 (rank : 405)
Query Neighborhood Hits	246	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H3T2, Q5JR71, Q8WXT8, Q8WXT9, Q8WXU0, Q96JF8	Gene names	SEMA6C, KIAA1869, SEMAY
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SEM6C_MOUSE
θ value	θ > 10 (rank : 468)	NC score	0.052923 (rank : 413)
Query Neighborhood Hits	246	Target Neighborhood Hits	352	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SEM6D_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.051652 (rank : 429)
Query Neighborhood Hits	246	Target Neighborhood Hits	169	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NFY4, Q8NFY3, Q8NFY5, Q8NFY6, Q8NFY7, Q9P249	Gene names	SEMA6D, KIAA1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

SEM6D_MOUSE
θ value	θ > 10 (rank : 470)	NC score	0.052002 (rank : 425)
Query Neighborhood Hits	246	Target Neighborhood Hits	161	Shared Neighborhood Hits	6
SwissProt Accessions	Q76KF0, Q76KF1, Q76KF2, Q76KF3, Q76KF4, Q80TD0	Gene names	Sema6d, Kiaa1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

SLIT1_HUMAN
θ value	θ > 10 (rank : 471)	NC score	0.077789 (rank : 295)
Query Neighborhood Hits	246	Target Neighborhood Hits	700	Shared Neighborhood Hits	56
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

SLIT1_MOUSE
θ value	θ > 10 (rank : 472)	NC score	0.079672 (rank : 287)
Query Neighborhood Hits	246	Target Neighborhood Hits	715	Shared Neighborhood Hits	61
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

SLIT2_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.083349 (rank : 276)
Query Neighborhood Hits	246	Target Neighborhood Hits	708	Shared Neighborhood Hits	59
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT2_MOUSE
θ value	θ > 10 (rank : 474)	NC score	0.079078 (rank : 290)
Query Neighborhood Hits	246	Target Neighborhood Hits	684	Shared Neighborhood Hits	52
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT3_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.077623 (rank : 296)
Query Neighborhood Hits	246	Target Neighborhood Hits	682	Shared Neighborhood Hits	53
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

SLIT3_MOUSE
θ value	θ > 10 (rank : 476)	NC score	0.078923 (rank : 292)
Query Neighborhood Hits	246	Target Neighborhood Hits	700	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

SREC2_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.071931 (rank : 312)
Query Neighborhood Hits	246	Target Neighborhood Hits	645	Shared Neighborhood Hits	61
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SREC2_MOUSE
θ value	θ > 10 (rank : 478)	NC score	0.070733 (rank : 316)
Query Neighborhood Hits	246	Target Neighborhood Hits	605	Shared Neighborhood Hits	59
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SREC_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.080908 (rank : 280)
Query Neighborhood Hits	246	Target Neighborhood Hits	645	Shared Neighborhood Hits	70
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

STAB1_MOUSE
θ value	θ > 10 (rank : 480)	NC score	0.090087 (rank : 250)
Query Neighborhood Hits	246	Target Neighborhood Hits	566	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

STAB2_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.090320 (rank : 248)
Query Neighborhood Hits	246	Target Neighborhood Hits	534	Shared Neighborhood Hits	58
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

SUSD1_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.119073 (rank : 168)
Query Neighborhood Hits	246	Target Neighborhood Hits	285	Shared Neighborhood Hits	36
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TENX_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.068911 (rank : 319)
Query Neighborhood Hits	246	Target Neighborhood Hits	789	Shared Neighborhood Hits	81
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TRBM_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.099640 (rank : 198)
Query Neighborhood Hits	246	Target Neighborhood Hits	339	Shared Neighborhood Hits	44
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRBM_MOUSE
θ value	θ > 10 (rank : 485)	NC score	0.100367 (rank : 193)
Query Neighborhood Hits	246	Target Neighborhood Hits	361	Shared Neighborhood Hits	47
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TSP3_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.155091 (rank : 153)
Query Neighborhood Hits	246	Target Neighborhood Hits	250	Shared Neighborhood Hits	29
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_MOUSE
θ value	θ > 10 (rank : 487)	NC score	0.151525 (rank : 155)
Query Neighborhood Hits	246	Target Neighborhood Hits	247	Shared Neighborhood Hits	29
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP4_HUMAN
θ value	θ > 10 (rank : 488)	NC score	0.146395 (rank : 158)
Query Neighborhood Hits	246	Target Neighborhood Hits	277	Shared Neighborhood Hits	33
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_MOUSE
θ value	θ > 10 (rank : 489)	NC score	0.145943 (rank : 159)
Query Neighborhood Hits	246	Target Neighborhood Hits	276	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

UROM_HUMAN
θ value	θ > 10 (rank : 490)	NC score	0.114870 (rank : 173)
Query Neighborhood Hits	246	Target Neighborhood Hits	284	Shared Neighborhood Hits	38
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_MOUSE
θ value	θ > 10 (rank : 491)	NC score	0.106983 (rank : 183)
Query Neighborhood Hits	246	Target Neighborhood Hits	276	Shared Neighborhood Hits	40
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

VLDLR_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.057896 (rank : 377)
Query Neighborhood Hits	246	Target Neighborhood Hits	383	Shared Neighborhood Hits	48
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
θ value	θ > 10 (rank : 493)	NC score	0.056365 (rank : 384)
Query Neighborhood Hits	246	Target Neighborhood Hits	360	Shared Neighborhood Hits	43
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VWF_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.053543 (rank : 406)
Query Neighborhood Hits	246	Target Neighborhood Hits	396	Shared Neighborhood Hits	52
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

WIF1_HUMAN
θ value	θ > 10 (rank : 495)	NC score	0.058113 (rank : 375)
Query Neighborhood Hits	246	Target Neighborhood Hits	392	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_MOUSE
θ value	θ > 10 (rank : 496)	NC score	0.057557 (rank : 378)
Query Neighborhood Hits	246	Target Neighborhood Hits	393	Shared Neighborhood Hits	48
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WISP2_HUMAN
θ value	θ > 10 (rank : 497)	NC score	0.100152 (rank : 195)
Query Neighborhood Hits	246	Target Neighborhood Hits	126	Shared Neighborhood Hits	58
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

WISP2_MOUSE
θ value	θ > 10 (rank : 498)	NC score	0.104359 (rank : 185)
Query Neighborhood Hits	246	Target Neighborhood Hits	129	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

WISP3_HUMAN
θ value	θ > 10 (rank : 499)	NC score	0.065298 (rank : 337)
Query Neighborhood Hits	246	Target Neighborhood Hits	87	Shared Neighborhood Hits	39
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

ZAN_HUMAN
θ value	θ > 10 (rank : 500)	NC score	0.070920 (rank : 315)
Query Neighborhood Hits	246	Target Neighborhood Hits	679	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

Hits sorted by NC score

BAI3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 5)
Query Neighborhood Hits	246	Target Neighborhood Hits	246	Shared Neighborhood Hits	246
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
NC score	0.999189 (rank : 2)	θ value	0 (rank : 6)
Query Neighborhood Hits	246	Target Neighborhood Hits	250	Shared Neighborhood Hits	230
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI2_MOUSE
NC score	0.984776 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	246	Target Neighborhood Hits	323	Shared Neighborhood Hits	185
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_HUMAN
NC score	0.984256 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	246	Target Neighborhood Hits	332	Shared Neighborhood Hits	185
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI1_MOUSE
NC score	0.982875 (rank : 5)	θ value	0 (rank : 2)
Query Neighborhood Hits	246	Target Neighborhood Hits	340	Shared Neighborhood Hits	178
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_HUMAN
NC score	0.980568 (rank : 6)	θ value	0 (rank : 1)
Query Neighborhood Hits	246	Target Neighborhood Hits	375	Shared Neighborhood Hits	182
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

PROP_MOUSE
NC score	0.725544 (rank : 7)	θ value	7.25919e-50 (rank : 8)
Query Neighborhood Hits	246	Target Neighborhood Hits	165	Shared Neighborhood Hits	90
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

PROP_HUMAN
NC score	0.715297 (rank : 8)	θ value	2.58786e-39 (rank : 15)
Query Neighborhood Hits	246	Target Neighborhood Hits	126	Shared Neighborhood Hits	87
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

GP133_HUMAN
NC score	0.694296 (rank : 9)	θ value	3.4976e-36 (rank : 19)
Query Neighborhood Hits	246	Target Neighborhood Hits	115	Shared Neighborhood Hits	88
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

EMR4_MOUSE
NC score	0.685867 (rank : 10)	θ value	2.05049e-36 (rank : 18)
Query Neighborhood Hits	246	Target Neighborhood Hits	191	Shared Neighborhood Hits	85
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

GP113_HUMAN
NC score	0.679235 (rank : 11)	θ value	1.29031e-22 (rank : 41)
Query Neighborhood Hits	246	Target Neighborhood Hits	102	Shared Neighborhood Hits	77
SwissProt Accessions	Q8IZF5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3	Gene names	GPR113, PGR23
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 113 precursor (G-protein coupled receptor PGR23).

GP128_HUMAN
NC score	0.659413 (rank : 12)	θ value	7.0802e-21 (rank : 49)
Query Neighborhood Hits	246	Target Neighborhood Hits	135	Shared Neighborhood Hits	76
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

GPR64_MOUSE
NC score	0.653557 (rank : 13)	θ value	2.59989e-23 (rank : 39)
Query Neighborhood Hits	246	Target Neighborhood Hits	156	Shared Neighborhood Hits	85
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

GPR64_HUMAN
NC score	0.650931 (rank : 14)	θ value	4.9032e-22 (rank : 47)
Query Neighborhood Hits	246	Target Neighborhood Hits	207	Shared Neighborhood Hits	83
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

ELTD1_HUMAN
NC score	0.650686 (rank : 15)	θ value	1.28732e-30 (rank : 28)
Query Neighborhood Hits	246	Target Neighborhood Hits	269	Shared Neighborhood Hits	98
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

EMR3_HUMAN
NC score	0.646064 (rank : 16)	θ value	1.12775e-26 (rank : 34)
Query Neighborhood Hits	246	Target Neighborhood Hits	245	Shared Neighborhood Hits	88
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

SPON1_MOUSE
NC score	0.638625 (rank : 17)	θ value	3.87602e-27 (rank : 33)
Query Neighborhood Hits	246	Target Neighborhood Hits	123	Shared Neighborhood Hits	97
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

SPON1_HUMAN
NC score	0.637714 (rank : 18)	θ value	3.28125e-26 (rank : 35)
Query Neighborhood Hits	246	Target Neighborhood Hits	117	Shared Neighborhood Hits	93
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

LPHN1_HUMAN
NC score	0.632684 (rank : 19)	θ value	5.57106e-42 (rank : 13)
Query Neighborhood Hits	246	Target Neighborhood Hits	155	Shared Neighborhood Hits	80
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

LPHN3_HUMAN
NC score	0.632339 (rank : 20)	θ value	1.79215e-40 (rank : 14)
Query Neighborhood Hits	246	Target Neighborhood Hits	139	Shared Neighborhood Hits	88
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

GPR97_MOUSE
NC score	0.632065 (rank : 21)	θ value	8.38298e-14 (rank : 71)
Query Neighborhood Hits	246	Target Neighborhood Hits	89	Shared Neighborhood Hits	79
SwissProt Accessions	Q8R0T6	Gene names	Gpr97
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor.

LPHN2_HUMAN
NC score	0.625623 (rank : 22)	θ value	2.26708e-35 (rank : 21)
Query Neighborhood Hits	246	Target Neighborhood Hits	136	Shared Neighborhood Hits	83
SwissProt Accessions	O95490, O94882, Q5VX76, Q9UKY5, Q9UKY6	Gene names	LPHN2, KIAA0786, LEC1, LPHH1
Domain Architecture
Description	Latrophilin-2 precursor (Calcium-independent alpha-latrotoxin receptor 2) (Latrophilin homolog 1) (Lectomedin-1).

GP110_HUMAN
NC score	0.622996 (rank : 23)	θ value	6.62687e-19 (rank : 53)
Query Neighborhood Hits	246	Target Neighborhood Hits	87	Shared Neighborhood Hits	63
SwissProt Accessions	Q5T601, Q5KU15, Q5T5Z9, Q86SM1, Q8IXE3, Q8IZF8, Q96DQ1	Gene names	GPR110, PGR19
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 110 precursor (G-protein coupled receptor PGR19) (G-protein coupled receptor KPG_012).

GP144_HUMAN
NC score	0.621434 (rank : 24)	θ value	1.38178e-16 (rank : 59)
Query Neighborhood Hits	246	Target Neighborhood Hits	108	Shared Neighborhood Hits	83
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

GP128_MOUSE
NC score	0.621214 (rank : 25)	θ value	6.00763e-12 (rank : 78)
Query Neighborhood Hits	246	Target Neighborhood Hits	141	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BM96, Q80T42	Gene names	Gpr128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

GP116_HUMAN
NC score	0.620935 (rank : 26)	θ value	3.28887e-18 (rank : 55)
Query Neighborhood Hits	246	Target Neighborhood Hits	167	Shared Neighborhood Hits	67
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

GP110_MOUSE
NC score	0.614951 (rank : 27)	θ value	8.65492e-19 (rank : 54)
Query Neighborhood Hits	246	Target Neighborhood Hits	92	Shared Neighborhood Hits	62
SwissProt Accessions	Q8VEC3, Q8BMV8	Gene names	Gpr110
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 110 precursor.

GPR56_HUMAN
NC score	0.606311 (rank : 28)	θ value	1.33837e-11 (rank : 82)
Query Neighborhood Hits	246	Target Neighborhood Hits	84	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y653, O95966, Q8NGB3, Q96HB4	Gene names	GPR56, TM7LN4, TM7XN1
Domain Architecture
Description	G-protein coupled receptor 56 precursor (TM7XN1 protein).

GPR97_HUMAN
NC score	0.604007 (rank : 29)	θ value	1.02475e-11 (rank : 80)
Query Neighborhood Hits	246	Target Neighborhood Hits	86	Shared Neighborhood Hits	75
SwissProt Accessions	Q86Y34, Q6ZMF4, Q86SL9, Q8IZF1	Gene names	GPR97, PGR26
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor (G-protein coupled receptor PGR26).

GP114_HUMAN
NC score	0.601973 (rank : 30)	θ value	1.99992e-07 (rank : 108)
Query Neighborhood Hits	246	Target Neighborhood Hits	75	Shared Neighborhood Hits	72
SwissProt Accessions	Q8IZF4, Q6ZMH7, Q6ZML4, Q86SL8, Q8IZ14	Gene names	GPR114, PGR27
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 114 precursor (G-protein coupled receptor PGR27).

GP112_HUMAN
NC score	0.597426 (rank : 31)	θ value	4.9032e-22 (rank : 46)
Query Neighborhood Hits	246	Target Neighborhood Hits	441	Shared Neighborhood Hits	84
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

GP115_HUMAN
NC score	0.597142 (rank : 32)	θ value	1.99529e-15 (rank : 63)
Query Neighborhood Hits	246	Target Neighborhood Hits	87	Shared Neighborhood Hits	63
SwissProt Accessions	Q8IZF3, Q5T5B5, Q5T5B6, Q86SN9, Q8IXE6	Gene names	GPR115, PGR18
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 (G-protein coupled receptor PGR18).

GP115_MOUSE
NC score	0.595914 (rank : 33)	θ value	1.33837e-11 (rank : 81)
Query Neighborhood Hits	246	Target Neighborhood Hits	69	Shared Neighborhood Hits	63
SwissProt Accessions	Q9D2L6	Gene names	Gpr115
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 precursor.

GPR56_MOUSE
NC score	0.588439 (rank : 34)	θ value	3.52202e-12 (rank : 75)
Query Neighborhood Hits	246	Target Neighborhood Hits	89	Shared Neighborhood Hits	78
SwissProt Accessions	Q8K209, Q3UR17, Q9QZT2	Gene names	Gpr56, Cyt28
Domain Architecture
Description	G-protein coupled receptor 56 precursor (Serpentine receptor cyt28).

ELTD1_MOUSE
NC score	0.579362 (rank : 35)	θ value	1.16434e-31 (rank : 26)
Query Neighborhood Hits	246	Target Neighborhood Hits	288	Shared Neighborhood Hits	98
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

GP126_HUMAN
NC score	0.562552 (rank : 36)	θ value	2.06002e-20 (rank : 51)
Query Neighborhood Hits	246	Target Neighborhood Hits	187	Shared Neighborhood Hits	87
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

CD97_MOUSE
NC score	0.547733 (rank : 37)	θ value	6.40375e-22 (rank : 48)
Query Neighborhood Hits	246	Target Neighborhood Hits	295	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

GP111_HUMAN
NC score	0.547699 (rank : 38)	θ value	2.13673e-09 (rank : 94)
Query Neighborhood Hits	246	Target Neighborhood Hits	77	Shared Neighborhood Hits	58
SwissProt Accessions	Q8IZF7, Q86SL6, Q8NGU5, Q8TDT5	Gene names	GPR111, PGR20
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 111 (G-protein coupled receptor PGR20).

UNC5A_MOUSE
NC score	0.545500 (rank : 39)	θ value	2.59989e-23 (rank : 40)
Query Neighborhood Hits	246	Target Neighborhood Hits	203	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

TSP2_HUMAN
NC score	0.542360 (rank : 40)	θ value	6.37413e-38 (rank : 16)
Query Neighborhood Hits	246	Target Neighborhood Hits	359	Shared Neighborhood Hits	122
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP2_MOUSE
NC score	0.542013 (rank : 41)	θ value	6.37413e-38 (rank : 17)
Query Neighborhood Hits	246	Target Neighborhood Hits	352	Shared Neighborhood Hits	120
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

UNC5B_MOUSE
NC score	0.541031 (rank : 42)	θ value	2.87452e-22 (rank : 43)
Query Neighborhood Hits	246	Target Neighborhood Hits	226	Shared Neighborhood Hits	78
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5B_HUMAN
NC score	0.539131 (rank : 43)	θ value	2.87452e-22 (rank : 42)
Query Neighborhood Hits	246	Target Neighborhood Hits	225	Shared Neighborhood Hits	78
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

TSP1_MOUSE
NC score	0.533743 (rank : 44)	θ value	4.568e-36 (rank : 20)
Query Neighborhood Hits	246	Target Neighborhood Hits	396	Shared Neighborhood Hits	119
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_HUMAN
NC score	0.530353 (rank : 45)	θ value	3.86705e-35 (rank : 22)
Query Neighborhood Hits	246	Target Neighborhood Hits	389	Shared Neighborhood Hits	121
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

UNC5C_HUMAN
NC score	0.527241 (rank : 46)	θ value	3.75424e-22 (rank : 45)
Query Neighborhood Hits	246	Target Neighborhood Hits	226	Shared Neighborhood Hits	77
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5C_MOUSE
NC score	0.527151 (rank : 47)	θ value	2.87452e-22 (rank : 44)
Query Neighborhood Hits	246	Target Neighborhood Hits	225	Shared Neighborhood Hits	77
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

ATL2_MOUSE
NC score	0.521688 (rank : 48)	θ value	1.02475e-11 (rank : 79)
Query Neighborhood Hits	246	Target Neighborhood Hits	137	Shared Neighborhood Hits	80
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

ATL2_HUMAN
NC score	0.519647 (rank : 49)	θ value	6.64225e-11 (rank : 86)
Query Neighborhood Hits	246	Target Neighborhood Hits	125	Shared Neighborhood Hits	77
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

CD97_HUMAN
NC score	0.513419 (rank : 50)	θ value	4.89182e-30 (rank : 29)
Query Neighborhood Hits	246	Target Neighborhood Hits	353	Shared Neighborhood Hits	103
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

EMR1_MOUSE
NC score	0.510384 (rank : 51)	θ value	5.0505e-35 (rank : 23)
Query Neighborhood Hits	246	Target Neighborhood Hits	349	Shared Neighborhood Hits	104
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

UNC5D_HUMAN
NC score	0.505480 (rank : 52)	θ value	2.69047e-20 (rank : 52)
Query Neighborhood Hits	246	Target Neighborhood Hits	267	Shared Neighborhood Hits	76
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5D_MOUSE
NC score	0.503729 (rank : 53)	θ value	1.2077e-20 (rank : 50)
Query Neighborhood Hits	246	Target Neighborhood Hits	268	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

EMR2_HUMAN
NC score	0.494638 (rank : 54)	θ value	1.99067e-23 (rank : 38)
Query Neighborhood Hits	246	Target Neighborhood Hits	345	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

ATS18_MOUSE
NC score	0.484627 (rank : 55)	θ value	1.24977e-17 (rank : 57)
Query Neighborhood Hits	246	Target Neighborhood Hits	163	Shared Neighborhood Hits	86
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

EMR1_HUMAN
NC score	0.484165 (rank : 56)	θ value	1.05554e-24 (rank : 37)
Query Neighborhood Hits	246	Target Neighborhood Hits	382	Shared Neighborhood Hits	107
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

ATS9_HUMAN
NC score	0.483505 (rank : 57)	θ value	4.02038e-16 (rank : 61)
Query Neighborhood Hits	246	Target Neighborhood Hits	219	Shared Neighborhood Hits	95
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

ATS16_MOUSE
NC score	0.481805 (rank : 58)	θ value	7.58209e-15 (rank : 68)
Query Neighborhood Hits	246	Target Neighborhood Hits	179	Shared Neighborhood Hits	94
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS16_HUMAN
NC score	0.481377 (rank : 59)	θ value	4.74913e-17 (rank : 58)
Query Neighborhood Hits	246	Target Neighborhood Hits	208	Shared Neighborhood Hits	95
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS13_HUMAN
NC score	0.479957 (rank : 60)	θ value	3.08544e-08 (rank : 100)
Query Neighborhood Hits	246	Target Neighborhood Hits	238	Shared Neighborhood Hits	84
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS18_HUMAN
NC score	0.479642 (rank : 61)	θ value	9.56915e-18 (rank : 56)
Query Neighborhood Hits	246	Target Neighborhood Hits	169	Shared Neighborhood Hits	87
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS17_HUMAN
NC score	0.478409 (rank : 62)	θ value	2.35696e-16 (rank : 60)
Query Neighborhood Hits	246	Target Neighborhood Hits	194	Shared Neighborhood Hits	90
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

ATS13_MOUSE
NC score	0.476190 (rank : 63)	θ value	6.87365e-08 (rank : 102)
Query Neighborhood Hits	246	Target Neighborhood Hits	227	Shared Neighborhood Hits	88
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS20_MOUSE
NC score	0.474683 (rank : 64)	θ value	7.58209e-15 (rank : 69)
Query Neighborhood Hits	246	Target Neighborhood Hits	225	Shared Neighborhood Hits	95
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS2_HUMAN
NC score	0.470346 (rank : 65)	θ value	6.41864e-14 (rank : 70)
Query Neighborhood Hits	246	Target Neighborhood Hits	179	Shared Neighborhood Hits	84
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS2_MOUSE
NC score	0.467938 (rank : 66)	θ value	1.16975e-15 (rank : 62)
Query Neighborhood Hits	246	Target Neighborhood Hits	179	Shared Neighborhood Hits	78
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS20_HUMAN
NC score	0.465455 (rank : 67)	θ value	3.40345e-15 (rank : 66)
Query Neighborhood Hits	246	Target Neighborhood Hits	192	Shared Neighborhood Hits	92
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATL5_HUMAN
NC score	0.463088 (rank : 68)	θ value	7.1131e-05 (rank : 129)
Query Neighborhood Hits	246	Target Neighborhood Hits	103	Shared Neighborhood Hits	75
SwissProt Accessions	Q6ZMM2, Q8IW95	Gene names	ADAMTSL5, THSD6
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 5 precursor (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6).

ATL1_HUMAN
NC score	0.462969 (rank : 69)	θ value	1.69304e-06 (rank : 117)
Query Neighborhood Hits	246	Target Neighborhood Hits	93	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N6G6, Q5T708, Q96RW4, Q9BXY3	Gene names	ADAMTSL1, ADAMTSR1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (ADAMTSL-1) (Punctin-1).

ATS14_HUMAN
NC score	0.462345 (rank : 70)	θ value	3.52202e-12 (rank : 74)
Query Neighborhood Hits	246	Target Neighborhood Hits	382	Shared Neighborhood Hits	82
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

ATL1_MOUSE
NC score	0.460588 (rank : 71)	θ value	2.88788e-06 (rank : 120)
Query Neighborhood Hits	246	Target Neighborhood Hits	80	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BLI0	Gene names	Adamtsl1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (Punctin-1).

SEM5B_MOUSE
NC score	0.460434 (rank : 72)	θ value	1.08979e-29 (rank : 30)
Query Neighborhood Hits	246	Target Neighborhood Hits	190	Shared Neighborhood Hits	91
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

SEM5A_HUMAN
NC score	0.459086 (rank : 73)	θ value	9.2256e-29 (rank : 31)
Query Neighborhood Hits	246	Target Neighborhood Hits	177	Shared Neighborhood Hits	90
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

ATS19_MOUSE
NC score	0.458429 (rank : 74)	θ value	3.40345e-15 (rank : 65)
Query Neighborhood Hits	246	Target Neighborhood Hits	188	Shared Neighborhood Hits	80
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

CRFR1_MOUSE
NC score	0.458332 (rank : 75)	θ value	8.67504e-11 (rank : 88)
Query Neighborhood Hits	246	Target Neighborhood Hits	83	Shared Neighborhood Hits	74
SwissProt Accessions	P35347	Gene names	Crhr1, Crhr
Domain Architecture
Description	Corticotropin-releasing factor receptor 1 precursor (CRF-R) (CRF1) (Corticotropin-releasing hormone receptor 1) (CRH-R 1).

SEM5B_HUMAN
NC score	0.458326 (rank : 76)	θ value	4.42448e-31 (rank : 27)
Query Neighborhood Hits	246	Target Neighborhood Hits	178	Shared Neighborhood Hits	87
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

ATS12_MOUSE
NC score	0.457938 (rank : 77)	θ value	4.59992e-12 (rank : 76)
Query Neighborhood Hits	246	Target Neighborhood Hits	220	Shared Neighborhood Hits	94
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS12_HUMAN
NC score	0.456482 (rank : 78)	θ value	4.16044e-13 (rank : 73)
Query Neighborhood Hits	246	Target Neighborhood Hits	251	Shared Neighborhood Hits	90
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

CRFR2_MOUSE
NC score	0.454799 (rank : 79)	θ value	6.64225e-11 (rank : 87)
Query Neighborhood Hits	246	Target Neighborhood Hits	76	Shared Neighborhood Hits	73
SwissProt Accessions	Q60748, Q60783, Q60808	Gene names	Crhr2, Crf2r
Domain Architecture
Description	Corticotropin-releasing factor receptor 2 precursor (CRF-R 2) (CRF2) (Corticotropin-releasing hormone receptor 2) (CRH-R 2) (CRF-RB) (CRH- R2).

SEM5A_MOUSE
NC score	0.453708 (rank : 80)	θ value	4.57862e-28 (rank : 32)
Query Neighborhood Hits	246	Target Neighborhood Hits	162	Shared Neighborhood Hits	87
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

ATS8_MOUSE
NC score	0.452965 (rank : 81)	θ value	8.97725e-08 (rank : 106)
Query Neighborhood Hits	246	Target Neighborhood Hits	139	Shared Neighborhood Hits	78
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

CRFR1_HUMAN
NC score	0.452948 (rank : 82)	θ value	1.133e-10 (rank : 89)
Query Neighborhood Hits	246	Target Neighborhood Hits	82	Shared Neighborhood Hits	73
SwissProt Accessions	P34998, Q13008, Q9UK64	Gene names	CRHR1, CRFR, CRFR1, CRHR
Domain Architecture
Description	Corticotropin-releasing factor receptor 1 precursor (CRF-R) (CRF1) (Corticotropin-releasing hormone receptor 1) (CRH-R 1).

ATS4_HUMAN
NC score	0.452417 (rank : 83)	θ value	2.36244e-08 (rank : 99)
Query Neighborhood Hits	246	Target Neighborhood Hits	138	Shared Neighborhood Hits	77
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

ATS4_MOUSE
NC score	0.451751 (rank : 84)	θ value	1.80886e-08 (rank : 97)
Query Neighborhood Hits	246	Target Neighborhood Hits	145	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

CRFR2_HUMAN
NC score	0.451167 (rank : 85)	θ value	5.08577e-11 (rank : 85)
Query Neighborhood Hits	246	Target Neighborhood Hits	76	Shared Neighborhood Hits	73
SwissProt Accessions	Q13324, O43461, Q99431	Gene names	CRHR2, CRF2R, CRH2R
Domain Architecture
Description	Corticotropin-releasing factor receptor 2 precursor (CRF-R 2) (CRF2) (Corticotropin-releasing hormone receptor 2) (CRH-R 2).

ATS19_HUMAN
NC score	0.450635 (rank : 86)	θ value	2.60593e-15 (rank : 64)
Query Neighborhood Hits	246	Target Neighborhood Hits	203	Shared Neighborhood Hits	79
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS1_MOUSE
NC score	0.450061 (rank : 87)	θ value	3.29651e-10 (rank : 90)
Query Neighborhood Hits	246	Target Neighborhood Hits	158	Shared Neighborhood Hits	84
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

ATS8_HUMAN
NC score	0.449089 (rank : 88)	θ value	8.97725e-08 (rank : 105)
Query Neighborhood Hits	246	Target Neighborhood Hits	145	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

ATS3_HUMAN
NC score	0.449004 (rank : 89)	θ value	2.98157e-11 (rank : 84)
Query Neighborhood Hits	246	Target Neighborhood Hits	179	Shared Neighborhood Hits	89
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS7_HUMAN
NC score	0.447118 (rank : 90)	θ value	6.00763e-12 (rank : 77)
Query Neighborhood Hits	246	Target Neighborhood Hits	169	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

ATS1_HUMAN
NC score	0.447106 (rank : 91)	θ value	3.64472e-09 (rank : 95)
Query Neighborhood Hits	246	Target Neighborhood Hits	159	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

ATS6_HUMAN
NC score	0.445728 (rank : 92)	θ value	5.81887e-07 (rank : 112)
Query Neighborhood Hits	246	Target Neighborhood Hits	141	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

GP123_HUMAN
NC score	0.445115 (rank : 93)	θ value	1.29631e-06 (rank : 116)
Query Neighborhood Hits	246	Target Neighborhood Hits	120	Shared Neighborhood Hits	47
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

ATS15_HUMAN
NC score	0.439746 (rank : 94)	θ value	6.87365e-08 (rank : 103)
Query Neighborhood Hits	246	Target Neighborhood Hits	151	Shared Neighborhood Hits	81
SwissProt Accessions	Q8TE58	Gene names	ADAMTS15
Domain Architecture
Description	ADAMTS-15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 15) (ADAM-TS 15) (ADAM-TS15).

GPR98_HUMAN
NC score	0.436815 (rank : 95)	θ value	6.87365e-08 (rank : 104)
Query Neighborhood Hits	246	Target Neighborhood Hits	202	Shared Neighborhood Hits	82
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

ATL3_HUMAN
NC score	0.436112 (rank : 96)	θ value	4.44505e-15 (rank : 67)
Query Neighborhood Hits	246	Target Neighborhood Hits	414	Shared Neighborhood Hits	86
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

THSD1_HUMAN
NC score	0.436009 (rank : 97)	θ value	3.19293e-05 (rank : 125)
Query Neighborhood Hits	246	Target Neighborhood Hits	136	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

SSPO_MOUSE
NC score	0.430490 (rank : 98)	θ value	3.62785e-25 (rank : 36)
Query Neighborhood Hits	246	Target Neighborhood Hits	800	Shared Neighborhood Hits	132
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

ATS5_MOUSE
NC score	0.429830 (rank : 99)	θ value	3.41135e-07 (rank : 109)
Query Neighborhood Hits	246	Target Neighborhood Hits	147	Shared Neighborhood Hits	79
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

GPR98_MOUSE
NC score	0.427564 (rank : 100)	θ value	5.62301e-10 (rank : 91)
Query Neighborhood Hits	246	Target Neighborhood Hits	206	Shared Neighborhood Hits	78
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

THSD1_MOUSE
NC score	0.426709 (rank : 101)	θ value	3.19293e-05 (rank : 126)
Query Neighborhood Hits	246	Target Neighborhood Hits	153	Shared Neighborhood Hits	75
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

ATS5_HUMAN
NC score	0.421699 (rank : 102)	θ value	6.43352e-06 (rank : 122)
Query Neighborhood Hits	246	Target Neighborhood Hits	141	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

CALCR_HUMAN
NC score	0.418195 (rank : 103)	θ value	9.59137e-10 (rank : 93)
Query Neighborhood Hits	246	Target Neighborhood Hits	67	Shared Neighborhood Hits	64
SwissProt Accessions	P30988, O14585, Q13941, Q6DJU8, Q6T712	Gene names	CALCR
Domain Architecture
Description	Calcitonin receptor precursor (CT-R).

UNC5A_HUMAN
NC score	0.415160 (rank : 104)	θ value	3.41135e-07 (rank : 110)
Query Neighborhood Hits	246	Target Neighborhood Hits	198	Shared Neighborhood Hits	73
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

CO6_HUMAN
NC score	0.397967 (rank : 105)	θ value	7.34386e-10 (rank : 92)
Query Neighborhood Hits	246	Target Neighborhood Hits	331	Shared Neighborhood Hits	98
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CALCR_MOUSE
NC score	0.395859 (rank : 106)	θ value	1.29631e-06 (rank : 115)
Query Neighborhood Hits	246	Target Neighborhood Hits	76	Shared Neighborhood Hits	68
SwissProt Accessions	Q60755	Gene names	Calcr
Domain Architecture
Description	Calcitonin receptor precursor (CT-R).

VIPR2_MOUSE
NC score	0.394557 (rank : 107)	θ value	1.17247e-07 (rank : 107)
Query Neighborhood Hits	246	Target Neighborhood Hits	98	Shared Neighborhood Hits	73
SwissProt Accessions	P41588, P97750	Gene names	Vipr2
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3).

VIPR1_MOUSE
NC score	0.393434 (rank : 108)	θ value	9.92553e-07 (rank : 114)
Query Neighborhood Hits	246	Target Neighborhood Hits	89	Shared Neighborhood Hits	76
SwissProt Accessions	P97751, Q9JI40, Q9R1T8	Gene names	Vipr1
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 1 precursor (VIP-R-1) (VPAC1) (Pituitary adenylate cyclase-activating polypeptide type II receptor) (PACAP type II receptor) (PACAP-R-2).

VIPR2_HUMAN
NC score	0.391181 (rank : 109)	θ value	1.80886e-08 (rank : 98)
Query Neighborhood Hits	246	Target Neighborhood Hits	97	Shared Neighborhood Hits	72
SwissProt Accessions	P41587, Q13053, Q15870	Gene names	VIPR2, VIP2R
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) (Helodermin-preferring VIP receptor).

PACR_MOUSE
NC score	0.388960 (rank : 110)	θ value	4.45536e-07 (rank : 111)
Query Neighborhood Hits	246	Target Neighborhood Hits	83	Shared Neighborhood Hits	74
SwissProt Accessions	P70205	Gene names	Adcyap1r1
Domain Architecture
Description	Pituitary adenylate cyclase-activating polypeptide type I receptor precursor (PACAP type I receptor) (PACAP-R-1).

CILP2_HUMAN
NC score	0.382126 (rank : 111)	θ value	2.88788e-06 (rank : 121)
Query Neighborhood Hits	246	Target Neighborhood Hits	307	Shared Neighborhood Hits	81
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

CO8B_MOUSE
NC score	0.381181 (rank : 112)	θ value	2.21117e-06 (rank : 119)
Query Neighborhood Hits	246	Target Neighborhood Hits	224	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

PTHR1_HUMAN
NC score	0.376780 (rank : 113)	θ value	5.44631e-05 (rank : 128)
Query Neighborhood Hits	246	Target Neighborhood Hits	85	Shared Neighborhood Hits	74
SwissProt Accessions	Q03431	Gene names	PTHR1, PTHR
Domain Architecture
Description	Parathyroid hormone/parathyroid hormone-related peptide receptor precursor (PTH/PTHr receptor) (PTH/PTHrP type I receptor).

VIPR1_HUMAN
NC score	0.372756 (rank : 114)	θ value	3.19293e-05 (rank : 127)
Query Neighborhood Hits	246	Target Neighborhood Hits	84	Shared Neighborhood Hits	71
SwissProt Accessions	P32241, Q15871	Gene names	VIPR1
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 1 precursor (VIP-R-1) (Pituitary adenylate cyclase-activating polypeptide type II receptor) (PACAP type II receptor) (PACAP-R-2).

PACR_HUMAN
NC score	0.371456 (rank : 115)	θ value	0.00134147 (rank : 135)
Query Neighborhood Hits	246	Target Neighborhood Hits	86	Shared Neighborhood Hits	76
SwissProt Accessions	P41586	Gene names	ADCYAP1R1
Domain Architecture
Description	Pituitary adenylate cyclase-activating polypeptide type I receptor precursor (PACAP type I receptor) (PACAP-R-1).

CALRL_HUMAN
NC score	0.366776 (rank : 116)	θ value	0.00298849 (rank : 140)
Query Neighborhood Hits	246	Target Neighborhood Hits	71	Shared Neighborhood Hits	67
SwissProt Accessions	Q16602	Gene names	CALCRL, CGRPR
Domain Architecture
Description	Calcitonin gene-related peptide type 1 receptor precursor (CGRP type 1 receptor) (Calcitonin receptor-like receptor).

CI094_HUMAN
NC score	0.362311 (rank : 117)	θ value	0.000461057 (rank : 132)
Query Neighborhood Hits	246	Target Neighborhood Hits	310	Shared Neighborhood Hits	73
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

PTHR1_MOUSE
NC score	0.362212 (rank : 118)	θ value	1.87187e-05 (rank : 124)
Query Neighborhood Hits	246	Target Neighborhood Hits	90	Shared Neighborhood Hits	72
SwissProt Accessions	P41593, Q62119	Gene names	Pthr1, Pthr
Domain Architecture
Description	Parathyroid hormone/parathyroid hormone-related peptide receptor precursor (PTH/PTHr receptor) (PTH/PTHrP type I receptor).

CALRL_MOUSE
NC score	0.362028 (rank : 119)	θ value	0.0148317 (rank : 151)
Query Neighborhood Hits	246	Target Neighborhood Hits	71	Shared Neighborhood Hits	67
SwissProt Accessions	Q9R1W5, Q9QXH8, Q9WUP2	Gene names	Calcrl, Crlr
Domain Architecture
Description	Calcitonin gene-related peptide type 1 receptor precursor (CGRP type 1 receptor) (Calcitonin receptor-like receptor).

CO8B_HUMAN
NC score	0.359838 (rank : 120)	θ value	9.92553e-07 (rank : 113)
Query Neighborhood Hits	246	Target Neighborhood Hits	199	Shared Neighborhood Hits	73
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CELR1_HUMAN
NC score	0.356347 (rank : 121)	θ value	5.03882e-43 (rank : 11)
Query Neighborhood Hits	246	Target Neighborhood Hits	613	Shared Neighborhood Hits	107
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

GLR_HUMAN
NC score	0.355547 (rank : 122)	θ value	6.43352e-06 (rank : 123)
Query Neighborhood Hits	246	Target Neighborhood Hits	77	Shared Neighborhood Hits	69
SwissProt Accessions	P47871	Gene names	GCGR
Domain Architecture
Description	Glucagon receptor precursor (GL-R).

GLP1R_MOUSE
NC score	0.354074 (rank : 123)	θ value	0.00298849 (rank : 141)
Query Neighborhood Hits	246	Target Neighborhood Hits	80	Shared Neighborhood Hits	69
SwissProt Accessions	O35659	Gene names	Glp1r
Domain Architecture
Description	Glucagon-like peptide 1 receptor precursor (GLP-1 receptor) (GLP-1-R) (GLP-1R).

CELR2_MOUSE
NC score	0.353358 (rank : 124)	θ value	1.32601e-43 (rank : 9)
Query Neighborhood Hits	246	Target Neighborhood Hits	584	Shared Neighborhood Hits	109
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

CELR1_MOUSE
NC score	0.352273 (rank : 125)	θ value	8.59492e-43 (rank : 12)
Query Neighborhood Hits	246	Target Neighborhood Hits	617	Shared Neighborhood Hits	114
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

HMCN1_HUMAN
NC score	0.352271 (rank : 126)	θ value	5.73848e-55 (rank : 7)
Query Neighborhood Hits	246	Target Neighborhood Hits	983	Shared Neighborhood Hits	132
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

SCTR_HUMAN
NC score	0.352270 (rank : 127)	θ value	0.00665767 (rank : 145)
Query Neighborhood Hits	246	Target Neighborhood Hits	70	Shared Neighborhood Hits	67
SwissProt Accessions	P47872, Q12961, Q13213	Gene names	SCTR
Domain Architecture
Description	Secretin receptor precursor (SCT-R).

CELR2_HUMAN
NC score	0.346742 (rank : 128)	θ value	2.95404e-43 (rank : 10)
Query Neighborhood Hits	246	Target Neighborhood Hits	657	Shared Neighborhood Hits	119
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

GHRHR_HUMAN
NC score	0.344686 (rank : 129)	θ value	0.00175202 (rank : 137)
Query Neighborhood Hits	246	Target Neighborhood Hits	78	Shared Neighborhood Hits	72
SwissProt Accessions	Q02643, Q99863	Gene names	GHRHR
Domain Architecture
Description	Growth hormone-releasing hormone receptor precursor (GHRH receptor) (GRF receptor) (GRFR).

GLP1R_HUMAN
NC score	0.341063 (rank : 130)	θ value	0.0148317 (rank : 152)
Query Neighborhood Hits	246	Target Neighborhood Hits	84	Shared Neighborhood Hits	67
SwissProt Accessions	P43220, Q99669	Gene names	GLP1R
Domain Architecture
Description	Glucagon-like peptide 1 receptor precursor (GLP-1 receptor) (GLP-1-R) (GLP-1R).

CO8A_MOUSE
NC score	0.339977 (rank : 131)	θ value	0.00390308 (rank : 142)
Query Neighborhood Hits	246	Target Neighborhood Hits	182	Shared Neighborhood Hits	73
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

GLR_MOUSE
NC score	0.338165 (rank : 132)	θ value	0.000158464 (rank : 131)
Query Neighborhood Hits	246	Target Neighborhood Hits	79	Shared Neighborhood Hits	68
SwissProt Accessions	Q61606, Q63960	Gene names	Gcgr
Domain Architecture
Description	Glucagon receptor precursor (GL-R).

SCTR_MOUSE
NC score	0.337941 (rank : 133)	θ value	0.000461057 (rank : 134)
Query Neighborhood Hits	246	Target Neighborhood Hits	69	Shared Neighborhood Hits	68
SwissProt Accessions	Q5FWI2, Q80T66	Gene names	Sctr
Domain Architecture	No domain graphic available
Description	Secretin receptor precursor (SCT-R).

GP125_HUMAN
NC score	0.337860 (rank : 134)	θ value	1.09485e-13 (rank : 72)
Query Neighborhood Hits	246	Target Neighborhood Hits	327	Shared Neighborhood Hits	50
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

CO8A_HUMAN
NC score	0.337857 (rank : 135)	θ value	0.21417 (rank : 159)
Query Neighborhood Hits	246	Target Neighborhood Hits	200	Shared Neighborhood Hits	77
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO7_HUMAN
NC score	0.336263 (rank : 136)	θ value	0.000121331 (rank : 130)
Query Neighborhood Hits	246	Target Neighborhood Hits	278	Shared Neighborhood Hits	82
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

GHRHR_MOUSE
NC score	0.331823 (rank : 137)	θ value	0.00175202 (rank : 138)
Query Neighborhood Hits	246	Target Neighborhood Hits	79	Shared Neighborhood Hits	71
SwissProt Accessions	P32082	Gene names	Ghrhr, Grfr
Domain Architecture	No domain graphic available
Description	Growth hormone-releasing hormone receptor precursor (GHRH receptor) (GRF receptor) (GRFR).

GIPR_HUMAN
NC score	0.327883 (rank : 138)	θ value	0.0113563 (rank : 148)
Query Neighborhood Hits	246	Target Neighborhood Hits	71	Shared Neighborhood Hits	69
SwissProt Accessions	P48546, Q14401, Q16400, Q9UPI1	Gene names	GIPR
Domain Architecture
Description	Gastric inhibitory polypeptide receptor precursor (GIP-R) (Glucose- dependent insulinotropic polypeptide receptor).

GP124_MOUSE
NC score	0.327029 (rank : 139)	θ value	6.21693e-09 (rank : 96)
Query Neighborhood Hits	246	Target Neighborhood Hits	423	Shared Neighborhood Hits	54
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

CELR3_HUMAN
NC score	0.324511 (rank : 140)	θ value	7.29293e-34 (rank : 25)
Query Neighborhood Hits	246	Target Neighborhood Hits	680	Shared Neighborhood Hits	117
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CELR3_MOUSE
NC score	0.324319 (rank : 141)	θ value	5.584e-34 (rank : 24)
Query Neighborhood Hits	246	Target Neighborhood Hits	687	Shared Neighborhood Hits	122
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

GP125_MOUSE
NC score	0.315931 (rank : 142)	θ value	2.28291e-11 (rank : 83)
Query Neighborhood Hits	246	Target Neighborhood Hits	329	Shared Neighborhood Hits	49
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

CILP1_MOUSE
NC score	0.312002 (rank : 143)	θ value	1.69304e-06 (rank : 118)
Query Neighborhood Hits	246	Target Neighborhood Hits	282	Shared Neighborhood Hits	79
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

GLP2R_HUMAN
NC score	0.310354 (rank : 144)	θ value	0.0148317 (rank : 153)
Query Neighborhood Hits	246	Target Neighborhood Hits	75	Shared Neighborhood Hits	70
SwissProt Accessions	O95838	Gene names	GLP2R
Domain Architecture
Description	Glucagon-like peptide 2 receptor precursor (GLP-2 receptor) (GLP-2-R) (GLP-2R).

PTHR2_HUMAN
NC score	0.304605 (rank : 145)	θ value	2.36792 (rank : 198)
Query Neighborhood Hits	246	Target Neighborhood Hits	81	Shared Neighborhood Hits	67
SwissProt Accessions	P49190, Q8N429	Gene names	PTHR2
Domain Architecture
Description	Parathyroid hormone receptor precursor (PTH2 receptor).

GP124_HUMAN
NC score	0.302113 (rank : 146)	θ value	4.0297e-08 (rank : 101)
Query Neighborhood Hits	246	Target Neighborhood Hits	304	Shared Neighborhood Hits	49
SwissProt Accessions	Q96PE1, Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4	Gene names	GPR124, KIAA1531, TEM5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

CILP1_HUMAN
NC score	0.293228 (rank : 147)	θ value	0.000461057 (rank : 133)
Query Neighborhood Hits	246	Target Neighborhood Hits	266	Shared Neighborhood Hits	81
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

PTHR2_MOUSE
NC score	0.292221 (rank : 148)	θ value	5.27518 (rank : 218)
Query Neighborhood Hits	246	Target Neighborhood Hits	84	Shared Neighborhood Hits	69
SwissProt Accessions	Q91V95	Gene names	Pthr2
Domain Architecture
Description	Parathyroid hormone receptor precursor (PTH2 receptor).

GP157_HUMAN
NC score	0.225175 (rank : 149)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	246	Target Neighborhood Hits	93	Shared Neighborhood Hits	56
SwissProt Accessions	Q5UAW9, Q8WWB8, Q9HA73	Gene names	GPR157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

GP157_MOUSE
NC score	0.218265 (rank : 150)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	246	Target Neighborhood Hits	78	Shared Neighborhood Hits	56
SwissProt Accessions	Q8C206, Q8C224	Gene names	Gpr157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

SPON2_HUMAN
NC score	0.190171 (rank : 151)	θ value	0.813845 (rank : 176)
Query Neighborhood Hits	246	Target Neighborhood Hits	53	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BUD6, Q9ULW1	Gene names	SPON2, DIL1
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin) (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1).

RSPO1_HUMAN
NC score	0.158142 (rank : 152)	θ value	0.0113563 (rank : 150)
Query Neighborhood Hits	246	Target Neighborhood Hits	101	Shared Neighborhood Hits	52
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

TSP3_HUMAN
NC score	0.155091 (rank : 153)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	246	Target Neighborhood Hits	250	Shared Neighborhood Hits	29
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

COMP_MOUSE
NC score	0.154348 (rank : 154)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	246	Target Neighborhood Hits	290	Shared Neighborhood Hits	32
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

TSP3_MOUSE
NC score	0.151525 (rank : 155)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	246	Target Neighborhood Hits	247	Shared Neighborhood Hits	29
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

SPON2_MOUSE
NC score	0.150495 (rank : 156)	θ value	1.81305 (rank : 194)
Query Neighborhood Hits	246	Target Neighborhood Hits	42	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).

COMP_HUMAN
NC score	0.149301 (rank : 157)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	246	Target Neighborhood Hits	258	Shared Neighborhood Hits	32
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

TSP4_HUMAN
NC score	0.146395 (rank : 158)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	246	Target Neighborhood Hits	277	Shared Neighborhood Hits	33
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_MOUSE
NC score	0.145943 (rank : 159)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	246	Target Neighborhood Hits	276	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

RSPO1_MOUSE
NC score	0.137302 (rank : 160)	θ value	0.365318 (rank : 168)
Query Neighborhood Hits	246	Target Neighborhood Hits	85	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

NELL1_HUMAN
NC score	0.130294 (rank : 161)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	246	Target Neighborhood Hits	451	Shared Neighborhood Hits	57
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NELL2_MOUSE
NC score	0.127662 (rank : 162)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	246	Target Neighborhood Hits	436	Shared Neighborhood Hits	49
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

RSPO3_MOUSE
NC score	0.126510 (rank : 163)	θ value	1.81305 (rank : 193)
Query Neighborhood Hits	246	Target Neighborhood Hits	120	Shared Neighborhood Hits	43
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

RSPO3_HUMAN
NC score	0.124473 (rank : 164)	θ value	1.81305 (rank : 192)
Query Neighborhood Hits	246	Target Neighborhood Hits	128	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

WISP1_MOUSE
NC score	0.124176 (rank : 165)	θ value	0.125558 (rank : 157)
Query Neighborhood Hits	246	Target Neighborhood Hits	123	Shared Neighborhood Hits	52
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

NELL2_HUMAN
NC score	0.124129 (rank : 166)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	246	Target Neighborhood Hits	449	Shared Neighborhood Hits	49
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

FRAS1_MOUSE
NC score	0.121405 (rank : 167)	θ value	0.00509761 (rank : 143)
Query Neighborhood Hits	246	Target Neighborhood Hits	747	Shared Neighborhood Hits	96
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

SUSD1_HUMAN
NC score	0.119073 (rank : 168)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	246	Target Neighborhood Hits	285	Shared Neighborhood Hits	36
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

RSPO4_MOUSE
NC score	0.116651 (rank : 169)	θ value	3.0926 (rank : 208)
Query Neighborhood Hits	246	Target Neighborhood Hits	110	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

CRUM1_HUMAN
NC score	0.116286 (rank : 170)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	246	Target Neighborhood Hits	457	Shared Neighborhood Hits	58
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

WISP1_HUMAN
NC score	0.115442 (rank : 171)	θ value	0.279714 (rank : 166)
Query Neighborhood Hits	246	Target Neighborhood Hits	121	Shared Neighborhood Hits	55
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

CRUM1_MOUSE
NC score	0.114942 (rank : 172)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	246	Target Neighborhood Hits	444	Shared Neighborhood Hits	56
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

UROM_HUMAN
NC score	0.114870 (rank : 173)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	246	Target Neighborhood Hits	284	Shared Neighborhood Hits	38
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

ADAM8_HUMAN
NC score	0.112314 (rank : 174)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	246	Target Neighborhood Hits	327	Shared Neighborhood Hits	63
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

FRAS1_HUMAN
NC score	0.111830 (rank : 175)	θ value	0.0961366 (rank : 155)
Query Neighborhood Hits	246	Target Neighborhood Hits	759	Shared Neighborhood Hits	89
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

ADAM8_MOUSE
NC score	0.109675 (rank : 176)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	246	Target Neighborhood Hits	326	Shared Neighborhood Hits	65
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

FBLN4_MOUSE
NC score	0.109092 (rank : 177)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	246	Target Neighborhood Hits	270	Shared Neighborhood Hits	41
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

ADA19_MOUSE
NC score	0.108515 (rank : 178)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	246	Target Neighborhood Hits	315	Shared Neighborhood Hits	56
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

CRUM2_HUMAN
NC score	0.108154 (rank : 179)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	246	Target Neighborhood Hits	453	Shared Neighborhood Hits	54
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

FBLN4_HUMAN
NC score	0.108041 (rank : 180)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	246	Target Neighborhood Hits	278	Shared Neighborhood Hits	43
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

C1QR1_MOUSE
NC score	0.107834 (rank : 181)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	246	Target Neighborhood Hits	342	Shared Neighborhood Hits	44
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

C1QR1_HUMAN
NC score	0.107184 (rank : 182)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	246	Target Neighborhood Hits	493	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

UROM_MOUSE
NC score	0.106983 (rank : 183)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	246	Target Neighborhood Hits	276	Shared Neighborhood Hits	40
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

MEGF6_HUMAN
NC score	0.104526 (rank : 184)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	246	Target Neighborhood Hits	671	Shared Neighborhood Hits	85
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

WISP2_MOUSE
NC score	0.104359 (rank : 185)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	246	Target Neighborhood Hits	129	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

LTBP4_MOUSE
NC score	0.104286 (rank : 186)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	246	Target Neighborhood Hits	607	Shared Neighborhood Hits	62
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

FBN1_HUMAN
NC score	0.103376 (rank : 187)	θ value	1.38821 (rank : 178)
Query Neighborhood Hits	246	Target Neighborhood Hits	557	Shared Neighborhood Hits	65
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

ADA19_HUMAN
NC score	0.100921 (rank : 188)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	246	Target Neighborhood Hits	381	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

FBLN3_HUMAN
NC score	0.100804 (rank : 189)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	246	Target Neighborhood Hits	293	Shared Neighborhood Hits	41
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FZD3_HUMAN
NC score	0.100723 (rank : 190)	θ value	0.00175202 (rank : 136)
Query Neighborhood Hits	246	Target Neighborhood Hits	74	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NPG1	Gene names	FZD3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (hFz3).

FBLN1_HUMAN
NC score	0.100706 (rank : 191)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	246	Target Neighborhood Hits	324	Shared Neighborhood Hits	45
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

ADA28_MOUSE
NC score	0.100648 (rank : 192)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	246	Target Neighborhood Hits	241	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

TRBM_MOUSE
NC score	0.100367 (rank : 193)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	246	Target Neighborhood Hits	361	Shared Neighborhood Hits	47
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

NID1_HUMAN
NC score	0.100213 (rank : 194)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	246	Target Neighborhood Hits	329	Shared Neighborhood Hits	42
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

WISP2_HUMAN
NC score	0.100152 (rank : 195)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	246	Target Neighborhood Hits	126	Shared Neighborhood Hits	58
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

FBN1_MOUSE
NC score	0.100102 (rank : 196)	θ value	8.99809 (rank : 232)
Query Neighborhood Hits	246	Target Neighborhood Hits	563	Shared Neighborhood Hits	65
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBLN5_HUMAN
NC score	0.099818 (rank : 197)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	246	Target Neighborhood Hits	329	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

TRBM_HUMAN
NC score	0.099640 (rank : 198)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	246	Target Neighborhood Hits	339	Shared Neighborhood Hits	44
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

FZD3_MOUSE
NC score	0.099497 (rank : 199)	θ value	0.00228821 (rank : 139)
Query Neighborhood Hits	246	Target Neighborhood Hits	75	Shared Neighborhood Hits	29
SwissProt Accessions	Q61086	Gene names	Fzd3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (mFz3).

RSPO4_HUMAN
NC score	0.099294 (rank : 200)	θ value	1.38821 (rank : 184)
Query Neighborhood Hits	246	Target Neighborhood Hits	110	Shared Neighborhood Hits	40
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

DLL1_HUMAN
NC score	0.098946 (rank : 201)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	246	Target Neighborhood Hits	455	Shared Neighborhood Hits	60
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

LTBP2_MOUSE
NC score	0.098672 (rank : 202)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	246	Target Neighborhood Hits	617	Shared Neighborhood Hits	63
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP2_HUMAN
NC score	0.098525 (rank : 203)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	246	Target Neighborhood Hits	552	Shared Neighborhood Hits	61
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

STAB2_MOUSE
NC score	0.098279 (rank : 204)	θ value	1.38821 (rank : 185)
Query Neighborhood Hits	246	Target Neighborhood Hits	528	Shared Neighborhood Hits	66
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

FBLN1_MOUSE
NC score	0.098204 (rank : 205)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	246	Target Neighborhood Hits	329	Shared Neighborhood Hits	44
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN3_MOUSE
NC score	0.097999 (rank : 206)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	246	Target Neighborhood Hits	279	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBN2_HUMAN
NC score	0.097747 (rank : 207)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	246	Target Neighborhood Hits	560	Shared Neighborhood Hits	68
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

DLL1_MOUSE
NC score	0.097502 (rank : 208)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	246	Target Neighborhood Hits	456	Shared Neighborhood Hits	60
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

EGF_HUMAN
NC score	0.097440 (rank : 209)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	246	Target Neighborhood Hits	343	Shared Neighborhood Hits	42
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

FBN2_MOUSE
NC score	0.097335 (rank : 210)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	246	Target Neighborhood Hits	549	Shared Neighborhood Hits	69
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

NID2_HUMAN
NC score	0.097261 (rank : 211)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	246	Target Neighborhood Hits	456	Shared Neighborhood Hits	47
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

STAB1_HUMAN
NC score	0.097100 (rank : 212)	θ value	8.99809 (rank : 244)
Query Neighborhood Hits	246	Target Neighborhood Hits	546	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

NID1_MOUSE
NC score	0.096988 (rank : 213)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	246	Target Neighborhood Hits	335	Shared Neighborhood Hits	40
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

ZAN_MOUSE
NC score	0.096923 (rank : 214)	θ value	0.21417 (rank : 163)
Query Neighborhood Hits	246	Target Neighborhood Hits	808	Shared Neighborhood Hits	82
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

FBLN5_MOUSE
NC score	0.096892 (rank : 215)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	246	Target Neighborhood Hits	317	Shared Neighborhood Hits	47
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

ADA28_HUMAN
NC score	0.096735 (rank : 216)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	246	Target Neighborhood Hits	244	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

FBN3_HUMAN
NC score	0.096717 (rank : 217)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	246	Target Neighborhood Hits	543	Shared Neighborhood Hits	58
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

CREL1_HUMAN
NC score	0.096691 (rank : 218)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	246	Target Neighborhood Hits	441	Shared Neighborhood Hits	43
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

LTBP3_HUMAN
NC score	0.096691 (rank : 219)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	246	Target Neighborhood Hits	502	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

NID2_MOUSE
NC score	0.096680 (rank : 220)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	246	Target Neighborhood Hits	338	Shared Neighborhood Hits	42
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

CYR61_HUMAN
NC score	0.096557 (rank : 221)	θ value	0.813845 (rank : 172)
Query Neighborhood Hits	246	Target Neighborhood Hits	159	Shared Neighborhood Hits	58
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

CUBN_MOUSE
NC score	0.096508 (rank : 222)	θ value	3.0926 (rank : 203)
Query Neighborhood Hits	246	Target Neighborhood Hits	477	Shared Neighborhood Hits	53
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

LTB1L_HUMAN
NC score	0.096200 (rank : 223)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	246	Target Neighborhood Hits	553	Shared Neighborhood Hits	58
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

ADA33_HUMAN
NC score	0.096196 (rank : 224)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	246	Target Neighborhood Hits	264	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA12_HUMAN
NC score	0.096133 (rank : 225)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	246	Target Neighborhood Hits	224	Shared Neighborhood Hits	45
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

CO9_MOUSE
NC score	0.095268 (rank : 226)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	246	Target Neighborhood Hits	153	Shared Neighborhood Hits	32
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

ADEC1_HUMAN
NC score	0.095171 (rank : 227)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	246	Target Neighborhood Hits	80	Shared Neighborhood Hits	27
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

EGF_MOUSE
NC score	0.094612 (rank : 228)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	246	Target Neighborhood Hits	358	Shared Neighborhood Hits	42
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

PROS_HUMAN
NC score	0.094414 (rank : 229)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	246	Target Neighborhood Hits	340	Shared Neighborhood Hits	35
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

LTB1L_MOUSE
NC score	0.094141 (rank : 230)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	246	Target Neighborhood Hits	514	Shared Neighborhood Hits	62
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

CREL1_MOUSE
NC score	0.094099 (rank : 231)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	246	Target Neighborhood Hits	524	Shared Neighborhood Hits	45
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

LTB1S_HUMAN
NC score	0.094099 (rank : 232)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	246	Target Neighborhood Hits	502	Shared Neighborhood Hits	49
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

PROS_MOUSE
NC score	0.094057 (rank : 233)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	246	Target Neighborhood Hits	330	Shared Neighborhood Hits	41
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

ADAM9_MOUSE
NC score	0.093727 (rank : 234)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	246	Target Neighborhood Hits	325	Shared Neighborhood Hits	53
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

FBLN2_MOUSE
NC score	0.093601 (rank : 235)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	246	Target Neighborhood Hits	505	Shared Neighborhood Hits	53
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

LTBP3_MOUSE
NC score	0.093416 (rank : 236)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	246	Target Neighborhood Hits	475	Shared Neighborhood Hits	54
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

ADA12_MOUSE
NC score	0.093340 (rank : 237)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	246	Target Neighborhood Hits	474	Shared Neighborhood Hits	45
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

LTB1S_MOUSE
NC score	0.092847 (rank : 238)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	246	Target Neighborhood Hits	479	Shared Neighborhood Hits	54
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

DNER_HUMAN
NC score	0.092790 (rank : 239)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	246	Target Neighborhood Hits	460	Shared Neighborhood Hits	58
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DLL4_HUMAN
NC score	0.092192 (rank : 240)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	246	Target Neighborhood Hits	435	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

ADA15_HUMAN
NC score	0.091315 (rank : 241)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	246	Target Neighborhood Hits	288	Shared Neighborhood Hits	56
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

NOTC3_MOUSE
NC score	0.091169 (rank : 242)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	246	Target Neighborhood Hits	975	Shared Neighborhood Hits	81
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

FBLN2_HUMAN
NC score	0.091001 (rank : 243)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	246	Target Neighborhood Hits	392	Shared Neighborhood Hits	48
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

JAG1_HUMAN
NC score	0.090700 (rank : 244)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	246	Target Neighborhood Hits	514	Shared Neighborhood Hits	61
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

SCUB3_HUMAN
NC score	0.090581 (rank : 245)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	246	Target Neighborhood Hits	428	Shared Neighborhood Hits	47
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

NOTC3_HUMAN
NC score	0.090554 (rank : 246)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	246	Target Neighborhood Hits	1062	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

JAG1_MOUSE
NC score	0.090471 (rank : 247)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	246	Target Neighborhood Hits	518	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

STAB2_HUMAN
NC score	0.090320 (rank : 248)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	246	Target Neighborhood Hits	534	Shared Neighborhood Hits	58
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

SCUB3_MOUSE
NC score	0.090270 (rank : 249)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	246	Target Neighborhood Hits	442	Shared Neighborhood Hits	49
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

STAB1_MOUSE
NC score	0.090087 (rank : 250)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	246	Target Neighborhood Hits	566	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

DNER_MOUSE
NC score	0.089302 (rank : 251)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	246	Target Neighborhood Hits	413	Shared Neighborhood Hits	59
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

DLL4_MOUSE
NC score	0.089268 (rank : 252)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	246	Target Neighborhood Hits	440	Shared Neighborhood Hits	61
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

ADAM7_MOUSE
NC score	0.088991 (rank : 253)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	246	Target Neighborhood Hits	200	Shared Neighborhood Hits	45
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

CUBN_HUMAN
NC score	0.088685 (rank : 254)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	246	Target Neighborhood Hits	482	Shared Neighborhood Hits	50
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

ADAM7_HUMAN
NC score	0.088272 (rank : 255)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	246	Target Neighborhood Hits	221	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

JAG2_HUMAN
NC score	0.087896 (rank : 256)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	246	Target Neighborhood Hits	491	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

ADA33_MOUSE
NC score	0.087483 (rank : 257)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	246	Target Neighborhood Hits	231	Shared Neighborhood Hits	49
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

DLK_HUMAN
NC score	0.087419 (rank : 258)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	246	Target Neighborhood Hits	401	Shared Neighborhood Hits	48
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

GAS6_MOUSE
NC score	0.087038 (rank : 259)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	246	Target Neighborhood Hits	343	Shared Neighborhood Hits	39
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

NOTC4_HUMAN
NC score	0.086879 (rank : 260)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	246	Target Neighborhood Hits	905	Shared Neighborhood Hits	71
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

GAS6_HUMAN
NC score	0.086815 (rank : 261)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	246	Target Neighborhood Hits	348	Shared Neighborhood Hits	38
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

KR106_HUMAN
NC score	0.086460 (rank : 262)	θ value	3.0926 (rank : 205)
Query Neighborhood Hits	246	Target Neighborhood Hits	347	Shared Neighborhood Hits	57
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

DLK_MOUSE
NC score	0.086401 (rank : 263)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	246	Target Neighborhood Hits	374	Shared Neighborhood Hits	50
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

NOTC2_HUMAN
NC score	0.086210 (rank : 264)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	246	Target Neighborhood Hits	1113	Shared Neighborhood Hits	76
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC1_MOUSE
NC score	0.086122 (rank : 265)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	246	Target Neighborhood Hits	916	Shared Neighborhood Hits	71
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC1_HUMAN
NC score	0.085998 (rank : 266)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	246	Target Neighborhood Hits	906	Shared Neighborhood Hits	80
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

FZD6_HUMAN
NC score	0.085851 (rank : 267)	θ value	0.00869519 (rank : 146)
Query Neighborhood Hits	246	Target Neighborhood Hits	84	Shared Neighborhood Hits	29
SwissProt Accessions	O60353, Q6P9C3	Gene names	FZD6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (hFz6).

KR414_HUMAN
NC score	0.085783 (rank : 268)	θ value	1.38821 (rank : 179)
Query Neighborhood Hits	246	Target Neighborhood Hits	199	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

ADAM9_HUMAN
NC score	0.085781 (rank : 269)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	246	Target Neighborhood Hits	243	Shared Neighborhood Hits	47
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

NOTC4_MOUSE
NC score	0.085757 (rank : 270)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	246	Target Neighborhood Hits	872	Shared Neighborhood Hits	69
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

JAG2_MOUSE
NC score	0.085523 (rank : 271)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	246	Target Neighborhood Hits	504	Shared Neighborhood Hits	61
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

NOV_HUMAN
NC score	0.084397 (rank : 272)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	246	Target Neighborhood Hits	128	Shared Neighborhood Hits	47
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

NOTC2_MOUSE
NC score	0.084277 (rank : 273)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	246	Target Neighborhood Hits	1069	Shared Neighborhood Hits	69
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOV_MOUSE
NC score	0.083827 (rank : 274)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	246	Target Neighborhood Hits	130	Shared Neighborhood Hits	49
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

DLL3_MOUSE
NC score	0.083601 (rank : 275)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	246	Target Neighborhood Hits	399	Shared Neighborhood Hits	50
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

SLIT2_HUMAN
NC score	0.083349 (rank : 276)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	246	Target Neighborhood Hits	708	Shared Neighborhood Hits	59
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

FATH_HUMAN
NC score	0.082997 (rank : 277)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	246	Target Neighborhood Hits	570	Shared Neighborhood Hits	44
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

FZD6_MOUSE
NC score	0.082809 (rank : 278)	θ value	0.00509761 (rank : 144)
Query Neighborhood Hits	246	Target Neighborhood Hits	135	Shared Neighborhood Hits	28
SwissProt Accessions	Q61089	Gene names	Fzd6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (mFz6).

CO9_HUMAN
NC score	0.081378 (rank : 279)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	246	Target Neighborhood Hits	147	Shared Neighborhood Hits	24
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

SREC_HUMAN
NC score	0.080908 (rank : 280)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	246	Target Neighborhood Hits	645	Shared Neighborhood Hits	70
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

DLL3_HUMAN
NC score	0.080424 (rank : 281)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	246	Target Neighborhood Hits	419	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

RSPO2_HUMAN
NC score	0.080213 (rank : 282)	θ value	8.99809 (rank : 241)
Query Neighborhood Hits	246	Target Neighborhood Hits	90	Shared Neighborhood Hits	39
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

LRP1_HUMAN
NC score	0.079926 (rank : 283)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	246	Target Neighborhood Hits	617	Shared Neighborhood Hits	73
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

KR101_HUMAN
NC score	0.079829 (rank : 284)	θ value	0.125558 (rank : 156)
Query Neighborhood Hits	246	Target Neighborhood Hits	261	Shared Neighborhood Hits	43
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

EGFL7_HUMAN
NC score	0.079821 (rank : 285)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	246	Target Neighborhood Hits	325	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

AGRIN_HUMAN
NC score	0.079715 (rank : 286)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	246	Target Neighborhood Hits	582	Shared Neighborhood Hits	57
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

SLIT1_MOUSE
NC score	0.079672 (rank : 287)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	246	Target Neighborhood Hits	715	Shared Neighborhood Hits	61
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

LRP2_HUMAN
NC score	0.079502 (rank : 288)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	246	Target Neighborhood Hits	573	Shared Neighborhood Hits	67
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

ADA15_MOUSE
NC score	0.079257 (rank : 289)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	246	Target Neighborhood Hits	324	Shared Neighborhood Hits	51
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

SLIT2_MOUSE
NC score	0.079078 (rank : 290)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	246	Target Neighborhood Hits	684	Shared Neighborhood Hits	52
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

EGFL9_MOUSE
NC score	0.079016 (rank : 291)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	246	Target Neighborhood Hits	379	Shared Neighborhood Hits	47
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

SLIT3_MOUSE
NC score	0.078923 (rank : 292)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	246	Target Neighborhood Hits	700	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

CYR61_MOUSE
NC score	0.078870 (rank : 293)	θ value	2.36792 (rank : 196)
Query Neighborhood Hits	246	Target Neighborhood Hits	156	Shared Neighborhood Hits	53
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

ADM1B_MOUSE
NC score	0.078107 (rank : 294)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	246	Target Neighborhood Hits	236	Shared Neighborhood Hits	52
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

SLIT1_HUMAN
NC score	0.077789 (rank : 295)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	246	Target Neighborhood Hits	700	Shared Neighborhood Hits	56
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

SLIT3_HUMAN
NC score	0.077623 (rank : 296)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	246	Target Neighborhood Hits	682	Shared Neighborhood Hits	53
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

MEGF8_HUMAN
NC score	0.077474 (rank : 297)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	246	Target Neighborhood Hits	528	Shared Neighborhood Hits	53
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

ADEC1_MOUSE
NC score	0.077253 (rank : 298)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	246	Target Neighborhood Hits	85	Shared Neighborhood Hits	30
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

KR104_HUMAN
NC score	0.077142 (rank : 299)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	246	Target Neighborhood Hits	313	Shared Neighborhood Hits	49
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

LRP1B_HUMAN
NC score	0.077039 (rank : 300)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	246	Target Neighborhood Hits	602	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

EGFL9_HUMAN
NC score	0.077023 (rank : 301)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	246	Target Neighborhood Hits	365	Shared Neighborhood Hits	48
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

ADM1A_MOUSE
NC score	0.076268 (rank : 302)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	246	Target Neighborhood Hits	230	Shared Neighborhood Hits	56
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ADA21_MOUSE
NC score	0.075624 (rank : 303)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	246	Target Neighborhood Hits	172	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

KR107_HUMAN
NC score	0.075579 (rank : 304)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	246	Target Neighborhood Hits	330	Shared Neighborhood Hits	48
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

LRP1B_MOUSE
NC score	0.075395 (rank : 305)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	246	Target Neighborhood Hits	606	Shared Neighborhood Hits	68
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

ADA22_HUMAN
NC score	0.074526 (rank : 306)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	246	Target Neighborhood Hits	211	Shared Neighborhood Hits	45
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

MEGF8_MOUSE
NC score	0.074294 (rank : 307)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	246	Target Neighborhood Hits	520	Shared Neighborhood Hits	51
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

RSPO2_MOUSE
NC score	0.073429 (rank : 308)	θ value	8.99809 (rank : 242)
Query Neighborhood Hits	246	Target Neighborhood Hits	88	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

KR102_HUMAN
NC score	0.073242 (rank : 309)	θ value	1.81305 (rank : 189)
Query Neighborhood Hits	246	Target Neighborhood Hits	264	Shared Neighborhood Hits	43
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

ADA23_MOUSE
NC score	0.073046 (rank : 310)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	246	Target Neighborhood Hits	245	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA24_MOUSE
NC score	0.072963 (rank : 311)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	246	Target Neighborhood Hits	230	Shared Neighborhood Hits	52
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

SREC2_HUMAN
NC score	0.071931 (rank : 312)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	246	Target Neighborhood Hits	645	Shared Neighborhood Hits	61
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

ADA22_MOUSE
NC score	0.071351 (rank : 313)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	246	Target Neighborhood Hits	225	Shared Neighborhood Hits	48
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

LYAM2_HUMAN
NC score	0.071002 (rank : 314)	θ value	0.00869519 (rank : 147)
Query Neighborhood Hits	246	Target Neighborhood Hits	394	Shared Neighborhood Hits	46
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

ZAN_HUMAN
NC score	0.070920 (rank : 315)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	246	Target Neighborhood Hits	679	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

SREC2_MOUSE
NC score	0.070733 (rank : 316)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	246	Target Neighborhood Hits	605	Shared Neighborhood Hits	59
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

ADA29_HUMAN
NC score	0.070006 (rank : 317)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	246	Target Neighborhood Hits	247	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

ADA23_HUMAN
NC score	0.069245 (rank : 318)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	246	Target Neighborhood Hits	235	Shared Neighborhood Hits	44
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

TENX_HUMAN
NC score	0.068911 (rank : 319)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	246	Target Neighborhood Hits	789	Shared Neighborhood Hits	81
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

ADA21_HUMAN
NC score	0.068724 (rank : 320)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	246	Target Neighborhood Hits	181	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

EGFL7_MOUSE
NC score	0.068595 (rank : 321)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	246	Target Neighborhood Hits	287	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

MATN2_HUMAN
NC score	0.068364 (rank : 322)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	246	Target Neighborhood Hits	365	Shared Neighborhood Hits	40
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

CRIM1_HUMAN
NC score	0.068363 (rank : 323)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	246	Target Neighborhood Hits	362	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

PCSK5_MOUSE
NC score	0.068171 (rank : 324)	θ value	0.62314 (rank : 170)
Query Neighborhood Hits	246	Target Neighborhood Hits	613	Shared Neighborhood Hits	70
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

ADA25_MOUSE
NC score	0.068137 (rank : 325)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	246	Target Neighborhood Hits	213	Shared Neighborhood Hits	37
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

AD26A_MOUSE
NC score	0.067965 (rank : 326)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	246	Target Neighborhood Hits	165	Shared Neighborhood Hits	43
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

FAT2_HUMAN
NC score	0.067918 (rank : 327)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	246	Target Neighborhood Hits	507	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

LDLR_HUMAN
NC score	0.067161 (rank : 328)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	246	Target Neighborhood Hits	375	Shared Neighborhood Hits	50
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

PGBM_MOUSE
NC score	0.067161 (rank : 329)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	246	Target Neighborhood Hits	1073	Shared Neighborhood Hits	64
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGBM_HUMAN
NC score	0.067144 (rank : 330)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	246	Target Neighborhood Hits	1113	Shared Neighborhood Hits	62
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

ADA11_MOUSE
NC score	0.066942 (rank : 331)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	246	Target Neighborhood Hits	263	Shared Neighborhood Hits	48
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

CAD23_MOUSE
NC score	0.066533 (rank : 332)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	246	Target Neighborhood Hits	208	Shared Neighborhood Hits	11
SwissProt Accessions	Q99PF4, Q99NH1, Q9D4N9	Gene names	Cdh23
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

MYOC_MOUSE
NC score	0.066488 (rank : 333)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	246	Target Neighborhood Hits	232	Shared Neighborhood Hits	4
SwissProt Accessions	O70624, O70289	Gene names	Myoc, Tigr
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

CAD23_HUMAN
NC score	0.066211 (rank : 334)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	246	Target Neighborhood Hits	197	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H251, Q6UWW1, Q9H4K9	Gene names	CDH23, KIAA1774
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

PCD15_MOUSE
NC score	0.065842 (rank : 335)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	246	Target Neighborhood Hits	262	Shared Neighborhood Hits	8
SwissProt Accessions	Q99PJ1	Gene names	Pcdh15
Domain Architecture
Description	Protocadherin-15 precursor.

PCD15_HUMAN
NC score	0.065699 (rank : 336)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	246	Target Neighborhood Hits	289	Shared Neighborhood Hits	7
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

WISP3_HUMAN
NC score	0.065298 (rank : 337)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	246	Target Neighborhood Hits	87	Shared Neighborhood Hits	39
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

OLFL1_HUMAN
NC score	0.064967 (rank : 338)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	246	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q6UWY5	Gene names	OLFML1
Domain Architecture	No domain graphic available
Description	Olfactomedin-like protein 1 precursor.

MATN4_HUMAN
NC score	0.064213 (rank : 339)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	246	Target Neighborhood Hits	287	Shared Neighborhood Hits	32
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

LDLR_MOUSE
NC score	0.063914 (rank : 340)	θ value	3.0926 (rank : 206)
Query Neighborhood Hits	246	Target Neighborhood Hits	382	Shared Neighborhood Hits	51
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

CSPG3_MOUSE
NC score	0.063910 (rank : 341)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	246	Target Neighborhood Hits	657	Shared Neighborhood Hits	38
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

KR412_HUMAN
NC score	0.063836 (rank : 342)	θ value	5.27518 (rank : 216)
Query Neighborhood Hits	246	Target Neighborhood Hits	178	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR109_HUMAN
NC score	0.063716 (rank : 343)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	246	Target Neighborhood Hits	226	Shared Neighborhood Hits	40
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

LRP4_HUMAN
NC score	0.063714 (rank : 344)	θ value	0.62314 (rank : 169)
Query Neighborhood Hits	246	Target Neighborhood Hits	355	Shared Neighborhood Hits	43
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP8_MOUSE
NC score	0.063621 (rank : 345)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	246	Target Neighborhood Hits	385	Shared Neighborhood Hits	50
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

PCD16_HUMAN
NC score	0.063506 (rank : 346)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	246	Target Neighborhood Hits	245	Shared Neighborhood Hits	8
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

PCDLK_HUMAN
NC score	0.063437 (rank : 347)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	246	Target Neighborhood Hits	172	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYE9, Q9NXP8	Gene names	PCLKC
Domain Architecture	No domain graphic available
Description	Protocadherin LKC precursor (PC-LKC).

LRP4_MOUSE
NC score	0.063263 (rank : 348)	θ value	1.38821 (rank : 180)
Query Neighborhood Hits	246	Target Neighborhood Hits	351	Shared Neighborhood Hits	45
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

EDIL3_HUMAN
NC score	0.062853 (rank : 349)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	246	Target Neighborhood Hits	292	Shared Neighborhood Hits	31
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

MATN2_MOUSE
NC score	0.062806 (rank : 350)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	246	Target Neighborhood Hits	356	Shared Neighborhood Hits	37
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

EDIL3_MOUSE
NC score	0.062464 (rank : 351)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	246	Target Neighborhood Hits	317	Shared Neighborhood Hits	31
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

NOE2_HUMAN
NC score	0.062216 (rank : 352)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	246	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	O95897, Q6IMJ3, Q96FC2	Gene names	OLFM2, NOE2
Domain Architecture
Description	Noelin-2 precursor (Olfactomedin-2).

NOE2_MOUSE
NC score	0.062183 (rank : 353)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	246	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BM13	Gene names	Olfm2
Domain Architecture	No domain graphic available
Description	Noelin-2 precursor (Olfactomedin-2).

CSPG2_MOUSE
NC score	0.062147 (rank : 354)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	246	Target Neighborhood Hits	711	Shared Neighborhood Hits	45
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

MUC5B_HUMAN
NC score	0.062067 (rank : 355)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	246	Target Neighborhood Hits	1020	Shared Neighborhood Hits	58
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

KRA51_HUMAN
NC score	0.061913 (rank : 356)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	246	Target Neighborhood Hits	288	Shared Neighborhood Hits	42
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

CSPG3_HUMAN
NC score	0.061627 (rank : 357)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	246	Target Neighborhood Hits	676	Shared Neighborhood Hits	40
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CTGF_MOUSE
NC score	0.061618 (rank : 358)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	246	Target Neighborhood Hits	124	Shared Neighborhood Hits	45
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

OLFL3_HUMAN
NC score	0.061603 (rank : 359)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	246	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRN5, Q53FR1, Q53HV9, Q5SQL6, Q69AX9, Q8NBJ2	Gene names	OLFML3
Domain Architecture
Description	Olfactomedin-like protein 3 precursor (HNOEL-iso) (hOLF44).

OLFL3_MOUSE
NC score	0.061566 (rank : 360)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	246	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BK62, Q3V2F2, Q8C1T0, Q99K37	Gene names	Olfml3
Domain Architecture	No domain graphic available
Description	Olfactomedin-like protein 3 precursor.

LRP8_HUMAN
NC score	0.061039 (rank : 361)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	246	Target Neighborhood Hits	346	Shared Neighborhood Hits	45
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

CTGF_HUMAN
NC score	0.060451 (rank : 362)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	246	Target Neighborhood Hits	128	Shared Neighborhood Hits	44
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

NOE3_HUMAN
NC score	0.060384 (rank : 363)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	246	Target Neighborhood Hits	109	Shared Neighborhood Hits	3
SwissProt Accessions	Q96PB7, Q8TBG1, Q96PB2, Q96PB3, Q96PB4, Q96PB5, Q96PB6	Gene names	OLFM3, NOE3
Domain Architecture
Description	Noelin-3 precursor (Olfactomedin-3) (Optimedin).

NOE3_MOUSE
NC score	0.060256 (rank : 364)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	246	Target Neighborhood Hits	116	Shared Neighborhood Hits	3
SwissProt Accessions	P63056, Q8BKV2, Q8BLL6, Q8QZW0, Q8R4K3, Q8R4K4	Gene names	Olfm3, Noe3
Domain Architecture	No domain graphic available
Description	Noelin-3 precursor (Olfactomedin-3) (Optimedin).

MEGF9_HUMAN
NC score	0.060223 (rank : 365)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	246	Target Neighborhood Hits	557	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MATN3_MOUSE
NC score	0.060052 (rank : 366)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	246	Target Neighborhood Hits	261	Shared Neighborhood Hits	29
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

CSPG2_HUMAN
NC score	0.059512 (rank : 367)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	246	Target Neighborhood Hits	681	Shared Neighborhood Hits	44
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

MATN3_HUMAN
NC score	0.059459 (rank : 368)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	246	Target Neighborhood Hits	268	Shared Neighborhood Hits	27
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

ADAM2_MOUSE
NC score	0.059317 (rank : 369)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	246	Target Neighborhood Hits	209	Shared Neighborhood Hits	47
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

LYAM2_MOUSE
NC score	0.059251 (rank : 370)	θ value	8.99809 (rank : 238)
Query Neighborhood Hits	246	Target Neighborhood Hits	420	Shared Neighborhood Hits	47
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

CD248_MOUSE
NC score	0.059016 (rank : 371)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	246	Target Neighborhood Hits	578	Shared Neighborhood Hits	31
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

NOE1_MOUSE
NC score	0.058714 (rank : 372)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	246	Target Neighborhood Hits	258	Shared Neighborhood Hits	6
SwissProt Accessions	O88998, O35429, O88999, Q91XK8, Q9QWQ9, Q9QWR0	Gene names	Olfm1, Noe1, Noel, Noel1
Domain Architecture
Description	Noelin precursor (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1) (Pancortin).

NRX2A_HUMAN
NC score	0.058180 (rank : 373)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	246	Target Neighborhood Hits	614	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NOE1_HUMAN
NC score	0.058123 (rank : 374)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	246	Target Neighborhood Hits	266	Shared Neighborhood Hits	6
SwissProt Accessions	Q99784, Q969S7, Q99452	Gene names	OLFM1, NOE1, NOEL1
Domain Architecture
Description	Noelin precursor (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1).

WIF1_HUMAN
NC score	0.058113 (rank : 375)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	246	Target Neighborhood Hits	392	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

CAD17_MOUSE
NC score	0.057960 (rank : 376)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	246	Target Neighborhood Hits	157	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R100	Gene names	Cdh17
Domain Architecture
Description	Cadherin-17 precursor (Liver-intestine-cadherin) (LI-cadherin) (BILL- cadherin) (P130).

VLDLR_HUMAN
NC score	0.057896 (rank : 377)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	246	Target Neighborhood Hits	383	Shared Neighborhood Hits	48
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

WIF1_MOUSE
NC score	0.057557 (rank : 378)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	246	Target Neighborhood Hits	393	Shared Neighborhood Hits	48
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

KRA45_HUMAN
NC score	0.057354 (rank : 379)	θ value	0.21417 (rank : 160)
Query Neighborhood Hits	246	Target Neighborhood Hits	194	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

ADA11_HUMAN
NC score	0.057220 (rank : 380)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	246	Target Neighborhood Hits	259	Shared Neighborhood Hits	48
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

KR105_HUMAN
NC score	0.056908 (rank : 381)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	246	Target Neighborhood Hits	271	Shared Neighborhood Hits	42
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

MYOC_HUMAN
NC score	0.056786 (rank : 382)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	246	Target Neighborhood Hits	489	Shared Neighborhood Hits	5
SwissProt Accessions	Q99972, O00620, Q7Z6Q9	Gene names	MYOC, GLC1A, TIGR
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

PCDH1_HUMAN
NC score	0.056403 (rank : 383)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	246	Target Neighborhood Hits	174	Shared Neighborhood Hits	6
SwissProt Accessions	Q08174	Gene names	PCDH1
Domain Architecture
Description	Protocadherin-1 precursor (Protocadherin-42) (PC42) (Cadherin-like protein 1).

VLDLR_MOUSE
NC score	0.056365 (rank : 384)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	246	Target Neighborhood Hits	360	Shared Neighborhood Hits	43
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

CAD17_HUMAN
NC score	0.056009 (rank : 385)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	246	Target Neighborhood Hits	154	Shared Neighborhood Hits	6
SwissProt Accessions	Q12864, Q15336	Gene names	CDH17
Domain Architecture
Description	Cadherin-17 precursor (Liver-intestine-cadherin) (LI-cadherin) (Intestinal peptide-associated transporter HPT-1).

BMPER_HUMAN
NC score	0.055876 (rank : 386)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	246	Target Neighborhood Hits	175	Shared Neighborhood Hits	33
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

EGFL8_MOUSE
NC score	0.055848 (rank : 387)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	246	Target Neighborhood Hits	266	Shared Neighborhood Hits	24
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

LAMC3_MOUSE
NC score	0.055677 (rank : 388)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	246	Target Neighborhood Hits	624	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

PCDH7_HUMAN
NC score	0.055430 (rank : 389)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	246	Target Neighborhood Hits	175	Shared Neighborhood Hits	6
SwissProt Accessions	O60245, O60246, O60247	Gene names	PCDH7, BHPCDH
Domain Architecture
Description	Protocadherin-7 precursor (Brain-heart protocadherin) (BH-Pcdh).

LAMA5_MOUSE
NC score	0.055419 (rank : 390)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	246	Target Neighborhood Hits	828	Shared Neighborhood Hits	60
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

NRX3A_HUMAN
NC score	0.055326 (rank : 391)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	246	Target Neighborhood Hits	164	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

LAMA5_HUMAN
NC score	0.055215 (rank : 392)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	246	Target Neighborhood Hits	976	Shared Neighborhood Hits	64
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

ADA17_MOUSE
NC score	0.054706 (rank : 393)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	246	Target Neighborhood Hits	201	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

PCD20_HUMAN
NC score	0.054584 (rank : 394)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	246	Target Neighborhood Hits	153	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N6Y1, Q8NDN4, Q9NRT9	Gene names	PCDH20
Domain Architecture	No domain graphic available
Description	Protocadherin-20 precursor (Protocadherin-13).

PCDH9_HUMAN
NC score	0.054582 (rank : 395)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	246	Target Neighborhood Hits	180	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HC56	Gene names	PCDH9
Domain Architecture
Description	Protocadherin-9 precursor.

PCD20_MOUSE
NC score	0.054529 (rank : 396)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	246	Target Neighborhood Hits	150	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BIZ0, Q8BIV2	Gene names	Pcdh20
Domain Architecture	No domain graphic available
Description	Protocadherin-20 precursor.

LAMB2_HUMAN
NC score	0.054416 (rank : 397)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	246	Target Neighborhood Hits	692	Shared Neighborhood Hits	46
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

ADA32_HUMAN
NC score	0.054272 (rank : 398)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	246	Target Neighborhood Hits	216	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

KRA92_HUMAN
NC score	0.054251 (rank : 399)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	246	Target Neighborhood Hits	198	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

CAD16_MOUSE
NC score	0.054236 (rank : 400)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	246	Target Neighborhood Hits	170	Shared Neighborhood Hits	8
SwissProt Accessions	O88338, Q9JLZ5	Gene names	Cdh16
Domain Architecture
Description	Cadherin-16 precursor (Kidney-specific cadherin) (Ksp-cadherin).

CAD16_HUMAN
NC score	0.054220 (rank : 401)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	246	Target Neighborhood Hits	159	Shared Neighborhood Hits	6
SwissProt Accessions	O75309, Q6UW93	Gene names	CDH16
Domain Architecture
Description	Cadherin-16 precursor (Kidney-specific cadherin) (Ksp-cadherin).

PC11Y_HUMAN
NC score	0.054076 (rank : 402)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	246	Target Neighborhood Hits	205	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BZA8, Q70LR6, Q70LR8, Q70LS0, Q70LS1, Q70LS2, Q70LS3, Q70LS4, Q70LS5, Q8WY34, Q9BZA9, Q9H4E1	Gene names	PCDH11Y, PCDH11, PCDH22, PCDHY
Domain Architecture	No domain graphic available
Description	Protocadherin-11 Y-linked precursor (Protocadherin-11) (Protocadherin- 22) (Protocadherin on the Y chromosome) (PCDH-Y) (Protocadherin prostate cancer) (Protocadherin-PC).

PC11X_HUMAN
NC score	0.053902 (rank : 403)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	246	Target Neighborhood Hits	199	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BZA7, Q2TJH0, Q2TJH1, Q2TJH3, Q5JVZ0, Q70LR8, Q70LS7, Q70LS8, Q70LS9, Q70LT7, Q70LT8, Q70LT9, Q70LU0, Q70LU1, Q96RV4, Q96RW0, Q9BZA6, Q9H4E0, Q9P2M0, Q9P2X5	Gene names	PCDH11X, PCDH11, PCDHX
Domain Architecture	No domain graphic available
Description	Protocadherin-11 X-linked precursor (Protocadherin-11) (Protocadherin on the X chromosome) (PCDH-X) (Protocadherin-S).

SEM6B_HUMAN
NC score	0.053831 (rank : 404)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	246	Target Neighborhood Hits	187	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

SEM6C_HUMAN
NC score	0.053649 (rank : 405)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	246	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H3T2, Q5JR71, Q8WXT8, Q8WXT9, Q8WXU0, Q96JF8	Gene names	SEMA6C, KIAA1869, SEMAY
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

VWF_HUMAN
NC score	0.053543 (rank : 406)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	246	Target Neighborhood Hits	396	Shared Neighborhood Hits	52
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

SEM6B_MOUSE
NC score	0.053491 (rank : 407)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	246	Target Neighborhood Hits	200	Shared Neighborhood Hits	4
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

NRX1A_HUMAN
NC score	0.053327 (rank : 408)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	246	Target Neighborhood Hits	170	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
NC score	0.053202 (rank : 409)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	246	Target Neighborhood Hits	164	Shared Neighborhood Hits	17
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

PROZ_HUMAN
NC score	0.053183 (rank : 410)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	246	Target Neighborhood Hits	422	Shared Neighborhood Hits	31
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

LYAM3_MOUSE
NC score	0.053067 (rank : 411)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	246	Target Neighborhood Hits	390	Shared Neighborhood Hits	43
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

BMPER_MOUSE
NC score	0.052955 (rank : 412)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	246	Target Neighborhood Hits	194	Shared Neighborhood Hits	37
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

SEM6C_MOUSE
NC score	0.052923 (rank : 413)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	246	Target Neighborhood Hits	352	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

ADA32_MOUSE
NC score	0.052815 (rank : 414)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	246	Target Neighborhood Hits	219	Shared Neighborhood Hits	44
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

FZD1_MOUSE
NC score	0.052766 (rank : 415)	θ value	0.813845 (rank : 173)
Query Neighborhood Hits	246	Target Neighborhood Hits	63	Shared Neighborhood Hits	30
SwissProt Accessions	O70421, O08974	Gene names	Fzd1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (mFz1).

PROZ_MOUSE
NC score	0.052755 (rank : 416)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	246	Target Neighborhood Hits	410	Shared Neighborhood Hits	29
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

CRDL2_MOUSE
NC score	0.052552 (rank : 417)	θ value	8.99809 (rank : 229)
Query Neighborhood Hits	246	Target Neighborhood Hits	81	Shared Neighborhood Hits	25
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

ROBO4_MOUSE
NC score	0.052518 (rank : 418)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	246	Target Neighborhood Hits	358	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

MUCDL_HUMAN
NC score	0.052468 (rank : 419)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	246	Target Neighborhood Hits	777	Shared Neighborhood Hits	14
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

SEM6A_MOUSE
NC score	0.052236 (rank : 420)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	246	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	O35464, Q6P5A8, Q6PCN9, Q9EQ71	Gene names	Sema6a, Semaq
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1) (Semaphorin Q) (Sema Q).

CU063_HUMAN
NC score	0.052115 (rank : 421)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	246	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	P58658, Q8IXZ0	Gene names	C21orf63
Domain Architecture
Description	Protein C21orf63 precursor (SUE21).

ADA20_HUMAN
NC score	0.052096 (rank : 422)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	246	Target Neighborhood Hits	143	Shared Neighborhood Hits	39
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

SEM4C_HUMAN
NC score	0.052081 (rank : 423)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	246	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q9C0C4, Q7Z5X0	Gene names	SEMA4C, KIAA1739
Domain Architecture
Description	Semaphorin-4C precursor.

ADA17_HUMAN
NC score	0.052019 (rank : 424)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	246	Target Neighborhood Hits	223	Shared Neighborhood Hits	51
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

SEM6D_MOUSE
NC score	0.052002 (rank : 425)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	246	Target Neighborhood Hits	161	Shared Neighborhood Hits	6
SwissProt Accessions	Q76KF0, Q76KF1, Q76KF2, Q76KF3, Q76KF4, Q80TD0	Gene names	Sema6d, Kiaa1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

SEM6A_HUMAN
NC score	0.051885 (rank : 426)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	246	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H2E6, Q9P2H9	Gene names	SEMA6A, KIAA1368
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1).

CD248_HUMAN
NC score	0.051778 (rank : 427)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	246	Target Neighborhood Hits	679	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

SEM3C_HUMAN
NC score	0.051684 (rank : 428)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	246	Target Neighborhood Hits	106	Shared Neighborhood Hits	9
SwissProt Accessions	Q99985	Gene names	SEMA3C, SEMAE
Domain Architecture
Description	Semaphorin-3C precursor (Semaphorin E) (Sema E).

SEM6D_HUMAN
NC score	0.051652 (rank : 429)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	246	Target Neighborhood Hits	169	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NFY4, Q8NFY3, Q8NFY5, Q8NFY6, Q8NFY7, Q9P249	Gene names	SEMA6D, KIAA1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

SEM3C_MOUSE
NC score	0.051616 (rank : 430)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	246	Target Neighborhood Hits	113	Shared Neighborhood Hits	10
SwissProt Accessions	Q62181	Gene names	Sema3c, Semae, SemE
Domain Architecture
Description	Semaphorin-3C precursor (Semaphorin E) (Sema E).

KR10A_HUMAN
NC score	0.051559 (rank : 431)	θ value	0.813845 (rank : 174)
Query Neighborhood Hits	246	Target Neighborhood Hits	232	Shared Neighborhood Hits	36
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

ADA18_MOUSE
NC score	0.051384 (rank : 432)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	246	Target Neighborhood Hits	227	Shared Neighborhood Hits	51
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

KRA98_HUMAN
NC score	0.051235 (rank : 433)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	246	Target Neighborhood Hits	185	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KR108_HUMAN
NC score	0.051195 (rank : 434)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	246	Target Neighborhood Hits	226	Shared Neighborhood Hits	34
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

SEM3F_HUMAN
NC score	0.051026 (rank : 435)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	246	Target Neighborhood Hits	100	Shared Neighborhood Hits	12
SwissProt Accessions	Q13275, Q13274, Q13372, Q15704	Gene names	SEMA3F
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV) (Sema III/F).

ADA10_MOUSE
NC score	0.050824 (rank : 436)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	246	Target Neighborhood Hits	194	Shared Neighborhood Hits	44
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA10_HUMAN
NC score	0.050813 (rank : 437)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	246	Target Neighborhood Hits	189	Shared Neighborhood Hits	44
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

GP155_HUMAN
NC score	0.050710 (rank : 438)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	246	Target Neighborhood Hits	42	Shared Neighborhood Hits	20
SwissProt Accessions	Q7Z3F1, Q53SJ3, Q53TA8, Q69YG8, Q86SP9, Q8N261, Q8N639, Q8N8K3, Q96MV6	Gene names	GPR155, PGR22
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR155 (G-protein coupled receptor PGR22).

SEM4A_HUMAN
NC score	0.050602 (rank : 439)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	246	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H3S1, Q8WUA9	Gene names	SEMA4A, SEMB
Domain Architecture
Description	Semaphorin-4A precursor (Semaphorin B) (Sema B).

SEM4C_MOUSE
NC score	0.050271 (rank : 440)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	246	Target Neighborhood Hits	77	Shared Neighborhood Hits	5
SwissProt Accessions	Q64151	Gene names	Sema4c, Semacl1, Semai
Domain Architecture
Description	Semaphorin-4C precursor (Semaphorin I) (Sema I) (Semaphorin C-like 1) (M-Sema F).

CU063_MOUSE
NC score	0.050271 (rank : 441)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	246	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	P58659	Gene names
Domain Architecture
Description	Protein C21orf63 homolog precursor.

MUC2_HUMAN
NC score	0.050084 (rank : 442)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	246	Target Neighborhood Hits	906	Shared Neighborhood Hits	38
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

SEM4A_MOUSE
NC score	0.050036 (rank : 443)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	246	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	Q62178	Gene names	Sema4a, Semab, SemB
Domain Architecture
Description	Semaphorin-4A precursor (Semaphorin B) (Sema B).

LYAM3_HUMAN
NC score	0.049635 (rank : 444)	θ value	3.0926 (rank : 207)
Query Neighborhood Hits	246	Target Neighborhood Hits	378	Shared Neighborhood Hits	42
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

TENA_HUMAN
NC score	0.049025 (rank : 445)	θ value	8.99809 (rank : 245)
Query Neighborhood Hits	246	Target Neighborhood Hits	631	Shared Neighborhood Hits	57
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

FZD5_HUMAN
NC score	0.046170 (rank : 446)	θ value	1.81305 (rank : 187)
Query Neighborhood Hits	246	Target Neighborhood Hits	71	Shared Neighborhood Hits	25
SwissProt Accessions	Q13467, Q53R22	Gene names	FZD5, HFZ5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (hFz5) (FzE5).

KRA42_HUMAN
NC score	0.046167 (rank : 447)	θ value	2.36792 (rank : 197)
Query Neighborhood Hits	246	Target Neighborhood Hits	149	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

FZD5_MOUSE
NC score	0.044678 (rank : 448)	θ value	1.81305 (rank : 188)
Query Neighborhood Hits	246	Target Neighborhood Hits	70	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EQD0, O08975, Q8BMR2, Q8CHK9	Gene names	Fzd5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (mFz5).

FZD1_HUMAN
NC score	0.042558 (rank : 449)	θ value	6.88961 (rank : 223)
Query Neighborhood Hits	246	Target Neighborhood Hits	62	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UP38, O94815, Q549T8	Gene names	FZD1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (hFz1) (FzE1).

KRA44_HUMAN
NC score	0.041489 (rank : 450)	θ value	1.81305 (rank : 190)
Query Neighborhood Hits	246	Target Neighborhood Hits	162	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

PCSK5_HUMAN
NC score	0.040585 (rank : 451)	θ value	1.38821 (rank : 183)
Query Neighborhood Hits	246	Target Neighborhood Hits	291	Shared Neighborhood Hits	39
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

KRA13_HUMAN
NC score	0.040042 (rank : 452)	θ value	8.99809 (rank : 237)
Query Neighborhood Hits	246	Target Neighborhood Hits	144	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

SORL_HUMAN
NC score	0.038056 (rank : 453)	θ value	2.36792 (rank : 199)
Query Neighborhood Hits	246	Target Neighborhood Hits	440	Shared Neighborhood Hits	41
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

FZD7_MOUSE
NC score	0.036991 (rank : 454)	θ value	5.27518 (rank : 215)
Query Neighborhood Hits	246	Target Neighborhood Hits	59	Shared Neighborhood Hits	22
SwissProt Accessions	Q61090	Gene names	Fzd7
Domain Architecture	No domain graphic available
Description	Frizzled-7 precursor (Fz-7) (mFz7).

FZD2_MOUSE
NC score	0.036174 (rank : 455)	θ value	8.99809 (rank : 234)
Query Neighborhood Hits	246	Target Neighborhood Hits	60	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JIP6, Q810M0, Q9JIP5, Q9WUJ2	Gene names	Fzd2, Fzd10
Domain Architecture
Description	Frizzled-2 precursor (Fz-2) (mFz2) (mFz10).

FZD2_HUMAN
NC score	0.035930 (rank : 456)	θ value	8.99809 (rank : 233)
Query Neighborhood Hits	246	Target Neighborhood Hits	57	Shared Neighborhood Hits	22
SwissProt Accessions	Q14332	Gene names	FZD2
Domain Architecture
Description	Frizzled-2 precursor (Fz-2) (hFz2) (FzE2).

CTNS_MOUSE
NC score	0.034033 (rank : 457)	θ value	0.813845 (rank : 171)
Query Neighborhood Hits	246	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	P57757	Gene names	Ctns
Domain Architecture
Description	Cystinosin.

CTNS_HUMAN
NC score	0.032403 (rank : 458)	θ value	1.06291 (rank : 177)
Query Neighborhood Hits	246	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	O60931, Q9UNK6	Gene names	CTNS
Domain Architecture
Description	Cystinosin.

TENN_MOUSE
NC score	0.024336 (rank : 459)	θ value	6.88961 (rank : 228)
Query Neighborhood Hits	246	Target Neighborhood Hits	484	Shared Neighborhood Hits	37
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

FUT4_MOUSE
NC score	0.024173 (rank : 460)	θ value	5.27518 (rank : 214)
Query Neighborhood Hits	246	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q11127	Gene names	Fut4, Elft
Domain Architecture
Description	Alpha-(1,3)-fucosyltransferase (EC 2.4.1.-) (Galactoside 3-L- fucosyltransferase) (Fucosyltransferase 4) (FUCT-IV) (Fuc-TIV).

MGR7_HUMAN
NC score	0.018876 (rank : 461)	θ value	0.21417 (rank : 161)
Query Neighborhood Hits	246	Target Neighborhood Hits	52	Shared Neighborhood Hits	7
SwissProt Accessions	Q14831, Q8NFS2, Q8NFS3, Q8NFS4	Gene names	GRM7, GPRC1G, MGLUR7
Domain Architecture
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

MGR7_MOUSE
NC score	0.018469 (rank : 462)	θ value	0.279714 (rank : 164)
Query Neighborhood Hits	246	Target Neighborhood Hits	53	Shared Neighborhood Hits	7
SwissProt Accessions	Q68ED2	Gene names	Grm7, Gprc1g, Mglur7
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

PTN_HUMAN
NC score	0.017828 (rank : 463)	θ value	5.27518 (rank : 219)
Query Neighborhood Hits	246	Target Neighborhood Hits	7	Shared Neighborhood Hits	5
SwissProt Accessions	P21246	Gene names	PTN, HBNF1, NEGF1
Domain Architecture
Description	Pleiotrophin precursor (PTN) (Heparin-binding growth-associated molecule) (HB-GAM) (Heparin-binding growth factor 8) (HBGF-8) (Osteoblast-specific factor 1) (OSF-1) (Heparin-binding neurite outgrowth-promoting factor 1) (HBNF-1) (Heparin-binding brain mitogen) (HBBM).

PTN_MOUSE
NC score	0.015840 (rank : 464)	θ value	6.88961 (rank : 227)
Query Neighborhood Hits	246	Target Neighborhood Hits	7	Shared Neighborhood Hits	5
SwissProt Accessions	P63089, P20935	Gene names	Ptn
Domain Architecture	No domain graphic available
Description	Pleiotrophin precursor (PTN) (Heparin-binding growth-associated molecule) (HB-GAM) (Heparin-binding growth factor 8) (HBGF-8) (Osteoblast-specific factor 1) (OSF-1) (Heparin-binding neutrophic factor) (HBNF) (Heparin-binding brain mitogen) (HBBM).

MGR4_HUMAN
NC score	0.015725 (rank : 465)	θ value	8.99809 (rank : 239)
Query Neighborhood Hits	246	Target Neighborhood Hits	63	Shared Neighborhood Hits	9
SwissProt Accessions	Q14833, Q5SZ84	Gene names	GRM4, GPRC1D, MGLUR4
Domain Architecture
Description	Metabotropic glutamate receptor 4 precursor (mGluR4).

MGR8_HUMAN
NC score	0.015652 (rank : 466)	θ value	1.38821 (rank : 181)
Query Neighborhood Hits	246	Target Neighborhood Hits	49	Shared Neighborhood Hits	7
SwissProt Accessions	O00222, O15493, O95945, O95946, Q3MIV9, Q52M02, Q6J165	Gene names	GRM8, GPRC1H, MGLUR8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

MGR8_MOUSE
NC score	0.015644 (rank : 467)	θ value	1.38821 (rank : 182)
Query Neighborhood Hits	246	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	P47743, Q6B964	Gene names	Grm8, Gprc1h, Mglur8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

UN13B_MOUSE
NC score	0.014754 (rank : 468)	θ value	2.36792 (rank : 201)
Query Neighborhood Hits	246	Target Neighborhood Hits	210	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

CSMD3_HUMAN
NC score	0.013325 (rank : 469)	θ value	2.36792 (rank : 195)
Query Neighborhood Hits	246	Target Neighborhood Hits	199	Shared Neighborhood Hits	18
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CMTA1_HUMAN
NC score	0.010467 (rank : 470)	θ value	6.88961 (rank : 222)
Query Neighborhood Hits	246	Target Neighborhood Hits	217	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

UN13A_HUMAN
NC score	0.009670 (rank : 471)	θ value	8.99809 (rank : 246)
Query Neighborhood Hits	246	Target Neighborhood Hits	285	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

UN13B_HUMAN
NC score	0.009532 (rank : 472)	θ value	5.27518 (rank : 221)
Query Neighborhood Hits	246	Target Neighborhood Hits	217	Shared Neighborhood Hits	7
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

EZH2_MOUSE
NC score	0.008012 (rank : 473)	θ value	8.99809 (rank : 231)
Query Neighborhood Hits	246	Target Neighborhood Hits	86	Shared Neighborhood Hits	11
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

AZIN1_MOUSE
NC score	0.007764 (rank : 474)	θ value	5.27518 (rank : 213)
Query Neighborhood Hits	246	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	O35484, Q542G5, Q8C2R8, Q8K1E5	Gene names	Azin1, Oazi, Oazin
Domain Architecture
Description	Antizyme inhibitor 1 (AZI) (Ornithine decarboxylase antizyme inhibitor).

DYH9_HUMAN
NC score	0.006290 (rank : 475)	θ value	3.0926 (rank : 204)
Query Neighborhood Hits	246	Target Neighborhood Hits	291	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NYC9, O95494, Q9NQ28	Gene names	DNAH9, DNAH17L, DNAL1
Domain Architecture
Description	Ciliary dynein heavy chain 9 (Axonemal beta dynein heavy chain 9).

EZH2_HUMAN
NC score	0.005793 (rank : 476)	θ value	8.99809 (rank : 230)
Query Neighborhood Hits	246	Target Neighborhood Hits	84	Shared Neighborhood Hits	9
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

K0776_HUMAN
NC score	0.004538 (rank : 477)	θ value	8.99809 (rank : 236)
Query Neighborhood Hits	246	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	O94874, Q8N765, Q9NTQ0	Gene names	KIAA0776
Domain Architecture	No domain graphic available
Description	Protein KIAA0776.

OR4B1_HUMAN
NC score	0.004348 (rank : 478)	θ value	0.0148317 (rank : 154)
Query Neighborhood Hits	246	Target Neighborhood Hits	652	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NGF8, Q6IF75, Q96R64	Gene names	OR4B1
Domain Architecture
Description	Olfactory receptor 4B1 (OST208) (Olfactory receptor OR11-106).

C163B_HUMAN
NC score	0.004149 (rank : 479)	θ value	1.81305 (rank : 186)
Query Neighborhood Hits	246	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NR16, Q6UWC2	Gene names	CD163L1, CD163B, M160
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M160 precursor (CD163 antigen-like 1) (CD163b antigen).

MRC1_HUMAN
NC score	0.003568 (rank : 480)	θ value	6.88961 (rank : 226)
Query Neighborhood Hits	246	Target Neighborhood Hits	157	Shared Neighborhood Hits	8
SwissProt Accessions	P22897	Gene names	MRC1
Domain Architecture
Description	Macrophage mannose receptor 1 precursor (MMR) (CD206 antigen).

MRC1_MOUSE
NC score	0.002504 (rank : 481)	θ value	8.99809 (rank : 240)
Query Neighborhood Hits	246	Target Neighborhood Hits	156	Shared Neighborhood Hits	7
SwissProt Accessions	Q61830, Q8C502	Gene names	Mrc1
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 1 precursor (MMR) (CD206 antigen).

GNRP_HUMAN
NC score	0.002367 (rank : 482)	θ value	6.88961 (rank : 224)
Query Neighborhood Hits	246	Target Neighborhood Hits	239	Shared Neighborhood Hits	4
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

O10J6_HUMAN
NC score	0.002007 (rank : 483)	θ value	0.279714 (rank : 165)
Query Neighborhood Hits	246	Target Neighborhood Hits	732	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NGY7, Q96R55	Gene names	OR10J6
Domain Architecture
Description	Olfactory receptor 10J6.

SPB8_MOUSE
NC score	0.001831 (rank : 484)	θ value	2.36792 (rank : 200)
Query Neighborhood Hits	246	Target Neighborhood Hits	84	Shared Neighborhood Hits	4
SwissProt Accessions	O08800	Gene names	Serpinb8
Domain Architecture	No domain graphic available
Description	Serpin B8.

O10A5_HUMAN
NC score	0.000450 (rank : 485)	θ value	0.0113563 (rank : 149)
Query Neighborhood Hits	246	Target Neighborhood Hits	767	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H207, Q52M66, Q96R22	Gene names	OR10A5
Domain Architecture
Description	Olfactory receptor 10A5 (HP3) (Olfactory receptor-like protein JCG6).

KI13A_MOUSE
NC score	0.000168 (rank : 486)	θ value	4.03905 (rank : 210)
Query Neighborhood Hits	246	Target Neighborhood Hits	395	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EQW7, O35062	Gene names	Kif13a
Domain Architecture
Description	Kinesin-like protein KIF13A.

FCGRN_HUMAN
NC score	0.000043 (rank : 487)	θ value	4.03905 (rank : 209)
Query Neighborhood Hits	246	Target Neighborhood Hits	177	Shared Neighborhood Hits	3
SwissProt Accessions	P55899, Q9HBV7, Q9NZ19	Gene names	FCGRT, FCRN
Domain Architecture	No domain graphic available
Description	IgG receptor FcRn large subunit p51 precursor (FcRn) (Neonatal Fc receptor) (IgG Fc fragment receptor transporter, alpha chain).

O10A4_HUMAN
NC score	-0.000072 (rank : 488)	θ value	0.163984 (rank : 158)
Query Neighborhood Hits	246	Target Neighborhood Hits	686	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H209, Q96R20	Gene names	OR10A4
Domain Architecture
Description	Olfactory receptor 10A4 (HP2) (Olfactory receptor-like protein JCG5).

OR4D1_HUMAN
NC score	-0.000391 (rank : 489)	θ value	0.813845 (rank : 175)
Query Neighborhood Hits	246	Target Neighborhood Hits	804	Shared Neighborhood Hits	13
SwissProt Accessions	Q15615, Q8NGB1, Q96R76	Gene names	OR4D1, OR4D3
Domain Architecture
Description	Olfactory receptor 4D1 (Olfactory receptor TPCR16).

OL142_MOUSE
NC score	-0.000910 (rank : 490)	θ value	0.21417 (rank : 162)
Query Neighborhood Hits	246	Target Neighborhood Hits	756	Shared Neighborhood Hits	11
SwissProt Accessions	Q60881, Q8VGP2	Gene names	Olfr142, Mor227-2, Olfr4
Domain Architecture	No domain graphic available
Description	Olfactory receptor 142 (Olfactory receptor 4C) (Olfactory receptor 227-2).

OR4L1_HUMAN
NC score	-0.001308 (rank : 491)	θ value	1.81305 (rank : 191)
Query Neighborhood Hits	246	Target Neighborhood Hits	784	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NH43, Q6IEZ5	Gene names	OR4L1
Domain Architecture
Description	Olfactory receptor 4L1 (Olfactory receptor OR14-28).

ATRX_HUMAN
NC score	-0.001645 (rank : 492)	θ value	3.0926 (rank : 202)
Query Neighborhood Hits	246	Target Neighborhood Hits	842	Shared Neighborhood Hits	5
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

IGF1R_HUMAN
NC score	-0.002429 (rank : 493)	θ value	6.88961 (rank : 225)
Query Neighborhood Hits	246	Target Neighborhood Hits	977	Shared Neighborhood Hits	39
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

OR4D9_HUMAN
NC score	-0.002760 (rank : 494)	θ value	5.27518 (rank : 217)
Query Neighborhood Hits	246	Target Neighborhood Hits	742	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NGE8, Q6IFF3	Gene names	OR4D9
Domain Architecture
Description	Olfactory receptor 4D9 (Olfactory receptor OR11-253).

SMC4_HUMAN
NC score	-0.003262 (rank : 495)	θ value	5.27518 (rank : 220)
Query Neighborhood Hits	246	Target Neighborhood Hits	937	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

OR1M1_HUMAN
NC score	-0.003677 (rank : 496)	θ value	4.03905 (rank : 212)
Query Neighborhood Hits	246	Target Neighborhood Hits	831	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NGA1, Q96R91	Gene names	OR1M1
Domain Architecture
Description	Olfactory receptor 1M1 (Olfactory receptor 19-6) (OR19-6).

SMC1A_MOUSE
NC score	-0.008033 (rank : 497)	θ value	8.99809 (rank : 243)
Query Neighborhood Hits	246	Target Neighborhood Hits	1384	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

M3K4_MOUSE
NC score	-0.008385 (rank : 498)	θ value	4.03905 (rank : 211)
Query Neighborhood Hits	246	Target Neighborhood Hits	924	Shared Neighborhood Hits	6
SwissProt Accessions	O08648, O08649, O70124	Gene names	Map3k4, Mekk4
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4).

HIPK1_MOUSE
NC score	-0.008614 (rank : 499)	θ value	8.99809 (rank : 235)
Query Neighborhood Hits	246	Target Neighborhood Hits	838	Shared Neighborhood Hits	5
SwissProt Accessions	O88904, Q80TV5, Q9QUQ8, Q9QZR3, Q9WVN7	Gene names	Hipk1, Kiaa0630, Myak, Nbak2
Domain Architecture
Description	Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Protein kinase Myak) (Nuclear body-associated kinase 2).

MRCKA_HUMAN
NC score	-0.009229 (rank : 500)	θ value	0.365318 (rank : 167)
Query Neighborhood Hits	246	Target Neighborhood Hits	1999	Shared Neighborhood Hits	12
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).