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Network neighborhood for query Sequence : EMR1_MOUSE

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EMR1_MOUSE
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EMR1_HUMAN
θ value	0 (rank : 1)	NC score	0.989332 (rank : 2)
Query Neighborhood Hits	349	Target Neighborhood Hits	382	Shared Neighborhood Hits	305
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EMR1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	349	Target Neighborhood Hits	349	Shared Neighborhood Hits	349
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EMR2_HUMAN
θ value	2.27638e-136 (rank : 3)	NC score	0.977855 (rank : 3)
Query Neighborhood Hits	349	Target Neighborhood Hits	345	Shared Neighborhood Hits	295
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

EMR3_HUMAN
θ value	4.9119e-131 (rank : 4)	NC score	0.873877 (rank : 8)
Query Neighborhood Hits	349	Target Neighborhood Hits	245	Shared Neighborhood Hits	220
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

CD97_HUMAN
θ value	3.76964e-123 (rank : 5)	NC score	0.976495 (rank : 4)
Query Neighborhood Hits	349	Target Neighborhood Hits	353	Shared Neighborhood Hits	297
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

EMR4_MOUSE
θ value	2.89973e-107 (rank : 6)	NC score	0.808956 (rank : 9)
Query Neighborhood Hits	349	Target Neighborhood Hits	191	Shared Neighborhood Hits	178
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

CD97_MOUSE
θ value	2.72669e-89 (rank : 7)	NC score	0.962191 (rank : 5)
Query Neighborhood Hits	349	Target Neighborhood Hits	295	Shared Neighborhood Hits	259
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

ELTD1_MOUSE
θ value	1.71185e-83 (rank : 8)	NC score	0.952938 (rank : 6)
Query Neighborhood Hits	349	Target Neighborhood Hits	288	Shared Neighborhood Hits	253
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

ELTD1_HUMAN
θ value	8.79181e-80 (rank : 9)	NC score	0.896054 (rank : 7)
Query Neighborhood Hits	349	Target Neighborhood Hits	269	Shared Neighborhood Hits	238
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

LPHN3_HUMAN
θ value	1.00591e-75 (rank : 10)	NC score	0.608182 (rank : 83)
Query Neighborhood Hits	349	Target Neighborhood Hits	139	Shared Neighborhood Hits	82
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

LPHN1_HUMAN
θ value	5.51964e-74 (rank : 11)	NC score	0.613127 (rank : 81)
Query Neighborhood Hits	349	Target Neighborhood Hits	155	Shared Neighborhood Hits	79
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

LPHN2_HUMAN
θ value	5.1662e-72 (rank : 12)	NC score	0.604543 (rank : 92)
Query Neighborhood Hits	349	Target Neighborhood Hits	136	Shared Neighborhood Hits	82
SwissProt Accessions	O95490, O94882, Q5VX76, Q9UKY5, Q9UKY6	Gene names	LPHN2, KIAA0786, LEC1, LPHH1
Domain Architecture
Description	Latrophilin-2 precursor (Calcium-independent alpha-latrotoxin receptor 2) (Latrophilin homolog 1) (Lectomedin-1).

LTB1L_MOUSE
θ value	7.01481e-53 (rank : 13)	NC score	0.742372 (rank : 24)
Query Neighborhood Hits	349	Target Neighborhood Hits	514	Shared Neighborhood Hits	257
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	7.01481e-53 (rank : 14)	NC score	0.744119 (rank : 21)
Query Neighborhood Hits	349	Target Neighborhood Hits	479	Shared Neighborhood Hits	256
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_HUMAN
θ value	2.041e-52 (rank : 15)	NC score	0.742158 (rank : 26)
Query Neighborhood Hits	349	Target Neighborhood Hits	553	Shared Neighborhood Hits	258
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	2.041e-52 (rank : 16)	NC score	0.742191 (rank : 25)
Query Neighborhood Hits	349	Target Neighborhood Hits	502	Shared Neighborhood Hits	257
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

GP133_HUMAN
θ value	9.48078e-50 (rank : 17)	NC score	0.665859 (rank : 50)
Query Neighborhood Hits	349	Target Neighborhood Hits	115	Shared Neighborhood Hits	82
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

CELR1_HUMAN
θ value	2.75849e-49 (rank : 18)	NC score	0.507159 (rank : 143)
Query Neighborhood Hits	349	Target Neighborhood Hits	613	Shared Neighborhood Hits	272
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

LTBP4_MOUSE
θ value	1.36902e-48 (rank : 19)	NC score	0.742644 (rank : 23)
Query Neighborhood Hits	349	Target Neighborhood Hits	607	Shared Neighborhood Hits	251
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

LTBP2_HUMAN
θ value	5.20228e-48 (rank : 20)	NC score	0.735802 (rank : 29)
Query Neighborhood Hits	349	Target Neighborhood Hits	552	Shared Neighborhood Hits	253
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

CELR1_MOUSE
θ value	2.58187e-47 (rank : 21)	NC score	0.506602 (rank : 144)
Query Neighborhood Hits	349	Target Neighborhood Hits	617	Shared Neighborhood Hits	275
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

LTBP2_MOUSE
θ value	2.58187e-47 (rank : 22)	NC score	0.736507 (rank : 28)
Query Neighborhood Hits	349	Target Neighborhood Hits	617	Shared Neighborhood Hits	253
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

FBN2_HUMAN
θ value	1.28137e-46 (rank : 23)	NC score	0.723524 (rank : 34)
Query Neighborhood Hits	349	Target Neighborhood Hits	560	Shared Neighborhood Hits	263
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
θ value	3.72821e-46 (rank : 24)	NC score	0.725436 (rank : 32)
Query Neighborhood Hits	349	Target Neighborhood Hits	543	Shared Neighborhood Hits	259
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FBN2_MOUSE
θ value	8.30557e-46 (rank : 25)	NC score	0.723368 (rank : 35)
Query Neighborhood Hits	349	Target Neighborhood Hits	549	Shared Neighborhood Hits	263
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

LTBP3_HUMAN
θ value	1.41672e-45 (rank : 26)	NC score	0.749635 (rank : 18)
Query Neighborhood Hits	349	Target Neighborhood Hits	502	Shared Neighborhood Hits	254
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

FBN1_HUMAN
θ value	2.67181e-44 (rank : 27)	NC score	0.726046 (rank : 31)
Query Neighborhood Hits	349	Target Neighborhood Hits	557	Shared Neighborhood Hits	264
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_MOUSE
θ value	3.48949e-44 (rank : 28)	NC score	0.724016 (rank : 33)
Query Neighborhood Hits	349	Target Neighborhood Hits	563	Shared Neighborhood Hits	263
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

CELR2_HUMAN
θ value	3.85808e-43 (rank : 29)	NC score	0.503433 (rank : 145)
Query Neighborhood Hits	349	Target Neighborhood Hits	657	Shared Neighborhood Hits	295
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CELR2_MOUSE
θ value	1.46607e-42 (rank : 30)	NC score	0.486344 (rank : 153)
Query Neighborhood Hits	349	Target Neighborhood Hits	584	Shared Neighborhood Hits	265
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

LTBP3_MOUSE
θ value	2.50074e-42 (rank : 31)	NC score	0.743892 (rank : 22)
Query Neighborhood Hits	349	Target Neighborhood Hits	475	Shared Neighborhood Hits	253
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

FBLN1_HUMAN
θ value	2.11701e-41 (rank : 32)	NC score	0.761105 (rank : 10)
Query Neighborhood Hits	349	Target Neighborhood Hits	324	Shared Neighborhood Hits	234
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

GPR64_HUMAN
θ value	1.79215e-40 (rank : 33)	NC score	0.634652 (rank : 74)
Query Neighborhood Hits	349	Target Neighborhood Hits	207	Shared Neighborhood Hits	81
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

FBLN1_MOUSE
θ value	3.05695e-40 (rank : 34)	NC score	0.759100 (rank : 12)
Query Neighborhood Hits	349	Target Neighborhood Hits	329	Shared Neighborhood Hits	239
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

GPR64_MOUSE
θ value	1.51715e-39 (rank : 35)	NC score	0.637816 (rank : 68)
Query Neighborhood Hits	349	Target Neighborhood Hits	156	Shared Neighborhood Hits	84
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

FBLN2_MOUSE
θ value	1.98146e-39 (rank : 36)	NC score	0.745056 (rank : 20)
Query Neighborhood Hits	349	Target Neighborhood Hits	505	Shared Neighborhood Hits	243
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

CELR3_MOUSE
θ value	3.37985e-39 (rank : 37)	NC score	0.483527 (rank : 156)
Query Neighborhood Hits	349	Target Neighborhood Hits	687	Shared Neighborhood Hits	281
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

FBLN2_HUMAN
θ value	4.41421e-39 (rank : 38)	NC score	0.747316 (rank : 19)
Query Neighborhood Hits	349	Target Neighborhood Hits	392	Shared Neighborhood Hits	238
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

CELR3_HUMAN
θ value	1.6774e-38 (rank : 39)	NC score	0.486592 (rank : 152)
Query Neighborhood Hits	349	Target Neighborhood Hits	680	Shared Neighborhood Hits	281
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

HMCN1_HUMAN
θ value	3.16345e-37 (rank : 40)	NC score	0.482265 (rank : 157)
Query Neighborhood Hits	349	Target Neighborhood Hits	983	Shared Neighborhood Hits	247
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

FBLN5_HUMAN
θ value	3.86705e-35 (rank : 41)	NC score	0.752940 (rank : 16)
Query Neighborhood Hits	349	Target Neighborhood Hits	329	Shared Neighborhood Hits	242
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

BAI3_HUMAN
θ value	5.0505e-35 (rank : 42)	NC score	0.510384 (rank : 140)
Query Neighborhood Hits	349	Target Neighborhood Hits	246	Shared Neighborhood Hits	104
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
θ value	5.0505e-35 (rank : 43)	NC score	0.510405 (rank : 139)
Query Neighborhood Hits	349	Target Neighborhood Hits	250	Shared Neighborhood Hits	105
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

FBLN5_MOUSE
θ value	1.46948e-34 (rank : 44)	NC score	0.751853 (rank : 17)
Query Neighborhood Hits	349	Target Neighborhood Hits	317	Shared Neighborhood Hits	236
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

GP144_HUMAN
θ value	3.27365e-34 (rank : 45)	NC score	0.607462 (rank : 85)
Query Neighborhood Hits	349	Target Neighborhood Hits	108	Shared Neighborhood Hits	84
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

GP112_HUMAN
θ value	5.584e-34 (rank : 46)	NC score	0.577603 (rank : 113)
Query Neighborhood Hits	349	Target Neighborhood Hits	441	Shared Neighborhood Hits	89
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

BAI1_HUMAN
θ value	7.29293e-34 (rank : 47)	NC score	0.515006 (rank : 133)
Query Neighborhood Hits	349	Target Neighborhood Hits	375	Shared Neighborhood Hits	99
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_MOUSE
θ value	4.72714e-33 (rank : 48)	NC score	0.513304 (rank : 136)
Query Neighborhood Hits	349	Target Neighborhood Hits	340	Shared Neighborhood Hits	99
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

NELL2_HUMAN
θ value	4.72714e-33 (rank : 49)	NC score	0.720098 (rank : 37)
Query Neighborhood Hits	349	Target Neighborhood Hits	449	Shared Neighborhood Hits	243
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

BAI2_HUMAN
θ value	5.22648e-32 (rank : 50)	NC score	0.509618 (rank : 141)
Query Neighborhood Hits	349	Target Neighborhood Hits	332	Shared Neighborhood Hits	103
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_MOUSE
θ value	6.82597e-32 (rank : 51)	NC score	0.511709 (rank : 138)
Query Neighborhood Hits	349	Target Neighborhood Hits	323	Shared Neighborhood Hits	106
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

NELL1_HUMAN
θ value	6.82597e-32 (rank : 52)	NC score	0.711937 (rank : 40)
Query Neighborhood Hits	349	Target Neighborhood Hits	451	Shared Neighborhood Hits	240
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NELL2_MOUSE
θ value	6.82597e-32 (rank : 53)	NC score	0.719012 (rank : 39)
Query Neighborhood Hits	349	Target Neighborhood Hits	436	Shared Neighborhood Hits	244
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NOTC1_MOUSE
θ value	1.52067e-31 (rank : 54)	NC score	0.613926 (rank : 80)
Query Neighborhood Hits	349	Target Neighborhood Hits	916	Shared Neighborhood Hits	261
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

FBLN3_MOUSE
θ value	2.59387e-31 (rank : 55)	NC score	0.753288 (rank : 14)
Query Neighborhood Hits	349	Target Neighborhood Hits	279	Shared Neighborhood Hits	220
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

SCUB3_MOUSE
θ value	7.54701e-31 (rank : 56)	NC score	0.719088 (rank : 38)
Query Neighborhood Hits	349	Target Neighborhood Hits	442	Shared Neighborhood Hits	243
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_HUMAN
θ value	9.8567e-31 (rank : 57)	NC score	0.720863 (rank : 36)
Query Neighborhood Hits	349	Target Neighborhood Hits	428	Shared Neighborhood Hits	244
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

GPR56_MOUSE
θ value	1.28732e-30 (rank : 58)	NC score	0.603698 (rank : 93)
Query Neighborhood Hits	349	Target Neighborhood Hits	89	Shared Neighborhood Hits	78
SwissProt Accessions	Q8K209, Q3UR17, Q9QZT2	Gene names	Gpr56, Cyt28
Domain Architecture
Description	G-protein coupled receptor 56 precursor (Serpentine receptor cyt28).

FBLN3_HUMAN
θ value	2.86786e-30 (rank : 59)	NC score	0.753250 (rank : 15)
Query Neighborhood Hits	349	Target Neighborhood Hits	293	Shared Neighborhood Hits	225
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

GP113_HUMAN
θ value	8.3442e-30 (rank : 60)	NC score	0.630862 (rank : 76)
Query Neighborhood Hits	349	Target Neighborhood Hits	102	Shared Neighborhood Hits	89
SwissProt Accessions	Q8IZF5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3	Gene names	GPR113, PGR23
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 113 precursor (G-protein coupled receptor PGR23).

NOTC4_MOUSE
θ value	8.3442e-30 (rank : 61)	NC score	0.587419 (rank : 108)
Query Neighborhood Hits	349	Target Neighborhood Hits	872	Shared Neighborhood Hits	257
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

GP126_HUMAN
θ value	1.4233e-29 (rank : 62)	NC score	0.570467 (rank : 122)
Query Neighborhood Hits	349	Target Neighborhood Hits	187	Shared Neighborhood Hits	101
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

NOTC3_HUMAN
θ value	2.42779e-29 (rank : 63)	NC score	0.599725 (rank : 99)
Query Neighborhood Hits	349	Target Neighborhood Hits	1062	Shared Neighborhood Hits	258
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
θ value	2.42779e-29 (rank : 64)	NC score	0.598332 (rank : 101)
Query Neighborhood Hits	349	Target Neighborhood Hits	975	Shared Neighborhood Hits	263
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

GPR56_HUMAN
θ value	9.2256e-29 (rank : 65)	NC score	0.614580 (rank : 79)
Query Neighborhood Hits	349	Target Neighborhood Hits	84	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y653, O95966, Q8NGB3, Q96HB4	Gene names	GPR56, TM7LN4, TM7XN1
Domain Architecture
Description	G-protein coupled receptor 56 precursor (TM7XN1 protein).

NOTC2_HUMAN
θ value	9.2256e-29 (rank : 66)	NC score	0.600493 (rank : 98)
Query Neighborhood Hits	349	Target Neighborhood Hits	1113	Shared Neighborhood Hits	262
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

MEGF6_HUMAN
θ value	1.2049e-28 (rank : 67)	NC score	0.641559 (rank : 66)
Query Neighborhood Hits	349	Target Neighborhood Hits	671	Shared Neighborhood Hits	261
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

NOTC1_HUMAN
θ value	1.57365e-28 (rank : 68)	NC score	0.596883 (rank : 102)
Query Neighborhood Hits	349	Target Neighborhood Hits	906	Shared Neighborhood Hits	262
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

FBLN4_HUMAN
θ value	5.97985e-28 (rank : 69)	NC score	0.759569 (rank : 11)
Query Neighborhood Hits	349	Target Neighborhood Hits	278	Shared Neighborhood Hits	226
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	5.97985e-28 (rank : 70)	NC score	0.758321 (rank : 13)
Query Neighborhood Hits	349	Target Neighborhood Hits	270	Shared Neighborhood Hits	222
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

GP128_HUMAN
θ value	1.02001e-27 (rank : 71)	NC score	0.634224 (rank : 75)
Query Neighborhood Hits	349	Target Neighborhood Hits	135	Shared Neighborhood Hits	94
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

NOTC2_MOUSE
θ value	1.33217e-27 (rank : 72)	NC score	0.601759 (rank : 96)
Query Neighborhood Hits	349	Target Neighborhood Hits	1069	Shared Neighborhood Hits	259
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

GP116_HUMAN
θ value	1.73987e-27 (rank : 73)	NC score	0.567448 (rank : 124)
Query Neighborhood Hits	349	Target Neighborhood Hits	167	Shared Neighborhood Hits	70
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

NOTC4_HUMAN
θ value	1.12775e-26 (rank : 74)	NC score	0.588726 (rank : 107)
Query Neighborhood Hits	349	Target Neighborhood Hits	905	Shared Neighborhood Hits	263
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

GP114_HUMAN
θ value	1.47289e-26 (rank : 75)	NC score	0.606286 (rank : 88)
Query Neighborhood Hits	349	Target Neighborhood Hits	75	Shared Neighborhood Hits	72
SwissProt Accessions	Q8IZF4, Q6ZMH7, Q6ZML4, Q86SL8, Q8IZ14	Gene names	GPR114, PGR27
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 114 precursor (G-protein coupled receptor PGR27).

CUBN_MOUSE
θ value	2.51237e-26 (rank : 76)	NC score	0.602484 (rank : 95)
Query Neighborhood Hits	349	Target Neighborhood Hits	477	Shared Neighborhood Hits	251
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CRUM1_MOUSE
θ value	1.24688e-25 (rank : 77)	NC score	0.667358 (rank : 49)
Query Neighborhood Hits	349	Target Neighborhood Hits	444	Shared Neighborhood Hits	241
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

MATN2_HUMAN
θ value	8.08199e-25 (rank : 78)	NC score	0.653463 (rank : 59)
Query Neighborhood Hits	349	Target Neighborhood Hits	365	Shared Neighborhood Hits	232
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

GPR97_MOUSE
θ value	1.80048e-24 (rank : 79)	NC score	0.605119 (rank : 89)
Query Neighborhood Hits	349	Target Neighborhood Hits	89	Shared Neighborhood Hits	79
SwissProt Accessions	Q8R0T6	Gene names	Gpr97
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor.

CRUM1_HUMAN
θ value	3.07116e-24 (rank : 80)	NC score	0.661628 (rank : 53)
Query Neighborhood Hits	349	Target Neighborhood Hits	457	Shared Neighborhood Hits	237
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

MATN2_MOUSE
θ value	4.01107e-24 (rank : 81)	NC score	0.646936 (rank : 60)
Query Neighborhood Hits	349	Target Neighborhood Hits	356	Shared Neighborhood Hits	227
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

C1QR1_MOUSE
θ value	5.23862e-24 (rank : 82)	NC score	0.739177 (rank : 27)
Query Neighborhood Hits	349	Target Neighborhood Hits	342	Shared Neighborhood Hits	235
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

GP128_MOUSE
θ value	6.84181e-24 (rank : 83)	NC score	0.616776 (rank : 77)
Query Neighborhood Hits	349	Target Neighborhood Hits	141	Shared Neighborhood Hits	94
SwissProt Accessions	Q8BM96, Q80T42	Gene names	Gpr128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

GP110_MOUSE
θ value	1.16704e-23 (rank : 84)	NC score	0.566968 (rank : 125)
Query Neighborhood Hits	349	Target Neighborhood Hits	92	Shared Neighborhood Hits	71
SwissProt Accessions	Q8VEC3, Q8BMV8	Gene names	Gpr110
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 110 precursor.

GP115_HUMAN
θ value	1.99067e-23 (rank : 85)	NC score	0.546700 (rank : 130)
Query Neighborhood Hits	349	Target Neighborhood Hits	87	Shared Neighborhood Hits	63
SwissProt Accessions	Q8IZF3, Q5T5B5, Q5T5B6, Q86SN9, Q8IXE6	Gene names	GPR115, PGR18
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 (G-protein coupled receptor PGR18).

C1QR1_HUMAN
θ value	3.39556e-23 (rank : 86)	NC score	0.732105 (rank : 30)
Query Neighborhood Hits	349	Target Neighborhood Hits	493	Shared Neighborhood Hits	228
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

GP110_HUMAN
θ value	3.39556e-23 (rank : 87)	NC score	0.569855 (rank : 123)
Query Neighborhood Hits	349	Target Neighborhood Hits	87	Shared Neighborhood Hits	68
SwissProt Accessions	Q5T601, Q5KU15, Q5T5Z9, Q86SM1, Q8IXE3, Q8IZF8, Q96DQ1	Gene names	GPR110, PGR19
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 110 precursor (G-protein coupled receptor PGR19) (G-protein coupled receptor KPG_012).

NID2_MOUSE
θ value	5.79196e-23 (rank : 88)	NC score	0.661195 (rank : 54)
Query Neighborhood Hits	349	Target Neighborhood Hits	338	Shared Neighborhood Hits	232
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

JAG1_MOUSE
θ value	1.29031e-22 (rank : 89)	NC score	0.644873 (rank : 63)
Query Neighborhood Hits	349	Target Neighborhood Hits	518	Shared Neighborhood Hits	247
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

GP115_MOUSE
θ value	1.6852e-22 (rank : 90)	NC score	0.550986 (rank : 128)
Query Neighborhood Hits	349	Target Neighborhood Hits	69	Shared Neighborhood Hits	63
SwissProt Accessions	Q9D2L6	Gene names	Gpr115
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 precursor.

JAG1_HUMAN
θ value	4.9032e-22 (rank : 91)	NC score	0.642765 (rank : 64)
Query Neighborhood Hits	349	Target Neighborhood Hits	514	Shared Neighborhood Hits	248
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

GAS6_HUMAN
θ value	8.36355e-22 (rank : 92)	NC score	0.692029 (rank : 45)
Query Neighborhood Hits	349	Target Neighborhood Hits	348	Shared Neighborhood Hits	237
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

CUBN_HUMAN
θ value	1.86321e-21 (rank : 93)	NC score	0.591294 (rank : 106)
Query Neighborhood Hits	349	Target Neighborhood Hits	482	Shared Neighborhood Hits	247
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

DLL1_HUMAN
θ value	1.86321e-21 (rank : 94)	NC score	0.635337 (rank : 73)
Query Neighborhood Hits	349	Target Neighborhood Hits	455	Shared Neighborhood Hits	242
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DLL1_MOUSE
θ value	5.42112e-21 (rank : 95)	NC score	0.636838 (rank : 70)
Query Neighborhood Hits	349	Target Neighborhood Hits	456	Shared Neighborhood Hits	239
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

GAS6_MOUSE
θ value	7.0802e-21 (rank : 96)	NC score	0.693644 (rank : 44)
Query Neighborhood Hits	349	Target Neighborhood Hits	343	Shared Neighborhood Hits	238
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GP111_HUMAN
θ value	1.2077e-20 (rank : 97)	NC score	0.517801 (rank : 132)
Query Neighborhood Hits	349	Target Neighborhood Hits	77	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IZF7, Q86SL6, Q8NGU5, Q8TDT5	Gene names	GPR111, PGR20
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 111 (G-protein coupled receptor PGR20).

NID2_HUMAN
θ value	1.5773e-20 (rank : 98)	NC score	0.654505 (rank : 57)
Query Neighborhood Hits	349	Target Neighborhood Hits	456	Shared Neighborhood Hits	231
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

GPR97_HUMAN
θ value	2.69047e-20 (rank : 99)	NC score	0.582430 (rank : 110)
Query Neighborhood Hits	349	Target Neighborhood Hits	86	Shared Neighborhood Hits	75
SwissProt Accessions	Q86Y34, Q6ZMF4, Q86SL9, Q8IZF1	Gene names	GPR97, PGR26
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor (G-protein coupled receptor PGR26).

JAG2_HUMAN
θ value	2.69047e-20 (rank : 100)	NC score	0.645221 (rank : 61)
Query Neighborhood Hits	349	Target Neighborhood Hits	491	Shared Neighborhood Hits	243
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

CRUM2_HUMAN
θ value	2.27762e-19 (rank : 101)	NC score	0.664883 (rank : 52)
Query Neighborhood Hits	349	Target Neighborhood Hits	453	Shared Neighborhood Hits	240
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

JAG2_MOUSE
θ value	2.97466e-19 (rank : 102)	NC score	0.642251 (rank : 65)
Query Neighborhood Hits	349	Target Neighborhood Hits	504	Shared Neighborhood Hits	241
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

NID1_MOUSE
θ value	5.07402e-19 (rank : 103)	NC score	0.656096 (rank : 56)
Query Neighborhood Hits	349	Target Neighborhood Hits	335	Shared Neighborhood Hits	222
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

UROM_HUMAN
θ value	6.62687e-19 (rank : 104)	NC score	0.676237 (rank : 48)
Query Neighborhood Hits	349	Target Neighborhood Hits	284	Shared Neighborhood Hits	214
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

PROS_HUMAN
θ value	1.13037e-18 (rank : 105)	NC score	0.690709 (rank : 46)
Query Neighborhood Hits	349	Target Neighborhood Hits	340	Shared Neighborhood Hits	239
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

NID1_HUMAN
θ value	1.47631e-18 (rank : 106)	NC score	0.656772 (rank : 55)
Query Neighborhood Hits	349	Target Neighborhood Hits	329	Shared Neighborhood Hits	232
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

EGF_HUMAN
θ value	1.92812e-18 (rank : 107)	NC score	0.645186 (rank : 62)
Query Neighborhood Hits	349	Target Neighborhood Hits	343	Shared Neighborhood Hits	231
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EGF_MOUSE
θ value	4.29542e-18 (rank : 108)	NC score	0.653571 (rank : 58)
Query Neighborhood Hits	349	Target Neighborhood Hits	358	Shared Neighborhood Hits	238
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

SUSD1_HUMAN
θ value	4.74913e-17 (rank : 109)	NC score	0.711157 (rank : 41)
Query Neighborhood Hits	349	Target Neighborhood Hits	285	Shared Neighborhood Hits	196
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

PROS_MOUSE
θ value	1.38178e-16 (rank : 110)	NC score	0.690193 (rank : 47)
Query Neighborhood Hits	349	Target Neighborhood Hits	330	Shared Neighborhood Hits	236
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

STAB1_MOUSE
θ value	1.80466e-16 (rank : 111)	NC score	0.565509 (rank : 126)
Query Neighborhood Hits	349	Target Neighborhood Hits	566	Shared Neighborhood Hits	240
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

SCTR_HUMAN
θ value	2.35696e-16 (rank : 112)	NC score	0.420815 (rank : 196)
Query Neighborhood Hits	349	Target Neighborhood Hits	70	Shared Neighborhood Hits	67
SwissProt Accessions	P47872, Q12961, Q13213	Gene names	SCTR
Domain Architecture
Description	Secretin receptor precursor (SCT-R).

GP125_HUMAN
θ value	8.95645e-16 (rank : 113)	NC score	0.320677 (rank : 235)
Query Neighborhood Hits	349	Target Neighborhood Hits	327	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

GPR98_MOUSE
θ value	8.95645e-16 (rank : 114)	NC score	0.407149 (rank : 201)
Query Neighborhood Hits	349	Target Neighborhood Hits	206	Shared Neighborhood Hits	78
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

DNER_HUMAN
θ value	1.16975e-15 (rank : 115)	NC score	0.637072 (rank : 69)
Query Neighborhood Hits	349	Target Neighborhood Hits	460	Shared Neighborhood Hits	228
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

UROM_MOUSE
θ value	1.52774e-15 (rank : 116)	NC score	0.665100 (rank : 51)
Query Neighborhood Hits	349	Target Neighborhood Hits	276	Shared Neighborhood Hits	209
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

DLL4_HUMAN
θ value	1.99529e-15 (rank : 117)	NC score	0.615905 (rank : 78)
Query Neighborhood Hits	349	Target Neighborhood Hits	435	Shared Neighborhood Hits	228
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DNER_MOUSE
θ value	1.99529e-15 (rank : 118)	NC score	0.636402 (rank : 71)
Query Neighborhood Hits	349	Target Neighborhood Hits	413	Shared Neighborhood Hits	226
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

TSP4_HUMAN
θ value	2.60593e-15 (rank : 119)	NC score	0.606483 (rank : 87)
Query Neighborhood Hits	349	Target Neighborhood Hits	277	Shared Neighborhood Hits	204
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

CRFR2_MOUSE
θ value	3.40345e-15 (rank : 120)	NC score	0.477272 (rank : 158)
Query Neighborhood Hits	349	Target Neighborhood Hits	76	Shared Neighborhood Hits	73
SwissProt Accessions	Q60748, Q60783, Q60808	Gene names	Crhr2, Crf2r
Domain Architecture
Description	Corticotropin-releasing factor receptor 2 precursor (CRF-R 2) (CRF2) (Corticotropin-releasing hormone receptor 2) (CRH-R 2) (CRF-RB) (CRH- R2).

TRBM_MOUSE
θ value	3.40345e-15 (rank : 121)	NC score	0.703409 (rank : 42)
Query Neighborhood Hits	349	Target Neighborhood Hits	361	Shared Neighborhood Hits	226
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

CRFR1_MOUSE
θ value	4.44505e-15 (rank : 122)	NC score	0.476098 (rank : 159)
Query Neighborhood Hits	349	Target Neighborhood Hits	83	Shared Neighborhood Hits	73
SwissProt Accessions	P35347	Gene names	Crhr1, Crhr
Domain Architecture
Description	Corticotropin-releasing factor receptor 1 precursor (CRF-R) (CRF1) (Corticotropin-releasing hormone receptor 1) (CRH-R 1).

CRFR2_HUMAN
θ value	4.44505e-15 (rank : 123)	NC score	0.469380 (rank : 164)
Query Neighborhood Hits	349	Target Neighborhood Hits	76	Shared Neighborhood Hits	73
SwissProt Accessions	Q13324, O43461, Q99431	Gene names	CRHR2, CRF2R, CRH2R
Domain Architecture
Description	Corticotropin-releasing factor receptor 2 precursor (CRF-R 2) (CRF2) (Corticotropin-releasing hormone receptor 2) (CRH-R 2).

GPR98_HUMAN
θ value	7.58209e-15 (rank : 124)	NC score	0.417958 (rank : 197)
Query Neighborhood Hits	349	Target Neighborhood Hits	202	Shared Neighborhood Hits	79
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

PTHR2_MOUSE
θ value	9.90251e-15 (rank : 125)	NC score	0.384461 (rank : 211)
Query Neighborhood Hits	349	Target Neighborhood Hits	84	Shared Neighborhood Hits	67
SwissProt Accessions	Q91V95	Gene names	Pthr2
Domain Architecture
Description	Parathyroid hormone receptor precursor (PTH2 receptor).

VIPR1_HUMAN
θ value	1.29331e-14 (rank : 126)	NC score	0.424059 (rank : 192)
Query Neighborhood Hits	349	Target Neighborhood Hits	84	Shared Neighborhood Hits	70
SwissProt Accessions	P32241, Q15871	Gene names	VIPR1
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 1 precursor (VIP-R-1) (Pituitary adenylate cyclase-activating polypeptide type II receptor) (PACAP type II receptor) (PACAP-R-2).

SLIT2_HUMAN
θ value	1.68911e-14 (rank : 127)	NC score	0.462587 (rank : 170)
Query Neighborhood Hits	349	Target Neighborhood Hits	708	Shared Neighborhood Hits	235
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

TSP3_MOUSE
θ value	1.68911e-14 (rank : 128)	NC score	0.571475 (rank : 119)
Query Neighborhood Hits	349	Target Neighborhood Hits	247	Shared Neighborhood Hits	181
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP4_MOUSE
θ value	2.20605e-14 (rank : 129)	NC score	0.607102 (rank : 86)
Query Neighborhood Hits	349	Target Neighborhood Hits	276	Shared Neighborhood Hits	208
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

STAB1_HUMAN
θ value	2.88119e-14 (rank : 130)	NC score	0.574446 (rank : 115)
Query Neighborhood Hits	349	Target Neighborhood Hits	546	Shared Neighborhood Hits	245
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

LRP2_HUMAN
θ value	3.76295e-14 (rank : 131)	NC score	0.496795 (rank : 147)
Query Neighborhood Hits	349	Target Neighborhood Hits	573	Shared Neighborhood Hits	255
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

TSP3_HUMAN
θ value	3.76295e-14 (rank : 132)	NC score	0.571460 (rank : 120)
Query Neighborhood Hits	349	Target Neighborhood Hits	250	Shared Neighborhood Hits	183
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

SCTR_MOUSE
θ value	6.41864e-14 (rank : 133)	NC score	0.406041 (rank : 202)
Query Neighborhood Hits	349	Target Neighborhood Hits	69	Shared Neighborhood Hits	68
SwissProt Accessions	Q5FWI2, Q80T66	Gene names	Sctr
Domain Architecture	No domain graphic available
Description	Secretin receptor precursor (SCT-R).

VIPR1_MOUSE
θ value	6.41864e-14 (rank : 134)	NC score	0.442869 (rank : 182)
Query Neighborhood Hits	349	Target Neighborhood Hits	89	Shared Neighborhood Hits	76
SwissProt Accessions	P97751, Q9JI40, Q9R1T8	Gene names	Vipr1
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 1 precursor (VIP-R-1) (VPAC1) (Pituitary adenylate cyclase-activating polypeptide type II receptor) (PACAP type II receptor) (PACAP-R-2).

GP125_MOUSE
θ value	8.38298e-14 (rank : 135)	NC score	0.301856 (rank : 243)
Query Neighborhood Hits	349	Target Neighborhood Hits	329	Shared Neighborhood Hits	55
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

SLIT1_MOUSE
θ value	1.09485e-13 (rank : 136)	NC score	0.471175 (rank : 162)
Query Neighborhood Hits	349	Target Neighborhood Hits	715	Shared Neighborhood Hits	231
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

SLIT3_HUMAN
θ value	1.09485e-13 (rank : 137)	NC score	0.448778 (rank : 179)
Query Neighborhood Hits	349	Target Neighborhood Hits	682	Shared Neighborhood Hits	220
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

GP124_HUMAN
θ value	1.86753e-13 (rank : 138)	NC score	0.297562 (rank : 248)
Query Neighborhood Hits	349	Target Neighborhood Hits	304	Shared Neighborhood Hits	56
SwissProt Accessions	Q96PE1, Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4	Gene names	GPR124, KIAA1531, TEM5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

STAB2_HUMAN
θ value	1.86753e-13 (rank : 139)	NC score	0.574088 (rank : 116)
Query Neighborhood Hits	349	Target Neighborhood Hits	534	Shared Neighborhood Hits	234
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

SLIT3_MOUSE
θ value	2.43908e-13 (rank : 140)	NC score	0.447921 (rank : 180)
Query Neighborhood Hits	349	Target Neighborhood Hits	700	Shared Neighborhood Hits	222
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

TRBM_HUMAN
θ value	2.43908e-13 (rank : 141)	NC score	0.702517 (rank : 43)
Query Neighborhood Hits	349	Target Neighborhood Hits	339	Shared Neighborhood Hits	231
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

GP124_MOUSE
θ value	4.16044e-13 (rank : 142)	NC score	0.321390 (rank : 233)
Query Neighborhood Hits	349	Target Neighborhood Hits	423	Shared Neighborhood Hits	61
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

VIPR2_HUMAN
θ value	4.16044e-13 (rank : 143)	NC score	0.428508 (rank : 188)
Query Neighborhood Hits	349	Target Neighborhood Hits	97	Shared Neighborhood Hits	74
SwissProt Accessions	P41587, Q13053, Q15870	Gene names	VIPR2, VIP2R
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) (Helodermin-preferring VIP receptor).

SLIT1_HUMAN
θ value	5.43371e-13 (rank : 144)	NC score	0.468814 (rank : 165)
Query Neighborhood Hits	349	Target Neighborhood Hits	700	Shared Neighborhood Hits	230
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

PACR_HUMAN
θ value	7.09661e-13 (rank : 145)	NC score	0.435737 (rank : 185)
Query Neighborhood Hits	349	Target Neighborhood Hits	86	Shared Neighborhood Hits	76
SwissProt Accessions	P41586	Gene names	ADCYAP1R1
Domain Architecture
Description	Pituitary adenylate cyclase-activating polypeptide type I receptor precursor (PACAP type I receptor) (PACAP-R-1).

STAB2_MOUSE
θ value	7.09661e-13 (rank : 146)	NC score	0.570938 (rank : 121)
Query Neighborhood Hits	349	Target Neighborhood Hits	528	Shared Neighborhood Hits	233
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

CALRL_MOUSE
θ value	9.26847e-13 (rank : 147)	NC score	0.421298 (rank : 195)
Query Neighborhood Hits	349	Target Neighborhood Hits	71	Shared Neighborhood Hits	66
SwissProt Accessions	Q9R1W5, Q9QXH8, Q9WUP2	Gene names	Calcrl, Crlr
Domain Architecture
Description	Calcitonin gene-related peptide type 1 receptor precursor (CGRP type 1 receptor) (Calcitonin receptor-like receptor).

COMP_MOUSE
θ value	9.26847e-13 (rank : 148)	NC score	0.594581 (rank : 103)
Query Neighborhood Hits	349	Target Neighborhood Hits	290	Shared Neighborhood Hits	190
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

DLL4_MOUSE
θ value	1.2105e-12 (rank : 149)	NC score	0.609782 (rank : 82)
Query Neighborhood Hits	349	Target Neighborhood Hits	440	Shared Neighborhood Hits	227
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

SLIT2_MOUSE
θ value	1.2105e-12 (rank : 150)	NC score	0.459682 (rank : 172)
Query Neighborhood Hits	349	Target Neighborhood Hits	684	Shared Neighborhood Hits	228
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

CALRL_HUMAN
θ value	1.58096e-12 (rank : 151)	NC score	0.422118 (rank : 194)
Query Neighborhood Hits	349	Target Neighborhood Hits	71	Shared Neighborhood Hits	66
SwissProt Accessions	Q16602	Gene names	CALCRL, CGRPR
Domain Architecture
Description	Calcitonin gene-related peptide type 1 receptor precursor (CGRP type 1 receptor) (Calcitonin receptor-like receptor).

PTHR1_HUMAN
θ value	6.00763e-12 (rank : 152)	NC score	0.428396 (rank : 189)
Query Neighborhood Hits	349	Target Neighborhood Hits	85	Shared Neighborhood Hits	73
SwissProt Accessions	Q03431	Gene names	PTHR1, PTHR
Domain Architecture
Description	Parathyroid hormone/parathyroid hormone-related peptide receptor precursor (PTH/PTHr receptor) (PTH/PTHrP type I receptor).

CREL1_HUMAN
θ value	1.02475e-11 (rank : 153)	NC score	0.638784 (rank : 67)
Query Neighborhood Hits	349	Target Neighborhood Hits	441	Shared Neighborhood Hits	206
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

PTHR2_HUMAN
θ value	1.02475e-11 (rank : 154)	NC score	0.391430 (rank : 208)
Query Neighborhood Hits	349	Target Neighborhood Hits	81	Shared Neighborhood Hits	66
SwissProt Accessions	P49190, Q8N429	Gene names	PTHR2
Domain Architecture
Description	Parathyroid hormone receptor precursor (PTH2 receptor).

GLP1R_MOUSE
θ value	1.74796e-11 (rank : 155)	NC score	0.423444 (rank : 193)
Query Neighborhood Hits	349	Target Neighborhood Hits	80	Shared Neighborhood Hits	69
SwissProt Accessions	O35659	Gene names	Glp1r
Domain Architecture
Description	Glucagon-like peptide 1 receptor precursor (GLP-1 receptor) (GLP-1-R) (GLP-1R).

COMP_HUMAN
θ value	2.28291e-11 (rank : 156)	NC score	0.582883 (rank : 109)
Query Neighborhood Hits	349	Target Neighborhood Hits	258	Shared Neighborhood Hits	185
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

LRP1_HUMAN
θ value	6.64225e-11 (rank : 157)	NC score	0.514952 (rank : 134)
Query Neighborhood Hits	349	Target Neighborhood Hits	617	Shared Neighborhood Hits	254
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

CRFR1_HUMAN
θ value	1.133e-10 (rank : 158)	NC score	0.466380 (rank : 168)
Query Neighborhood Hits	349	Target Neighborhood Hits	82	Shared Neighborhood Hits	72
SwissProt Accessions	P34998, Q13008, Q9UK64	Gene names	CRHR1, CRFR, CRFR1, CRHR
Domain Architecture
Description	Corticotropin-releasing factor receptor 1 precursor (CRF-R) (CRF1) (Corticotropin-releasing hormone receptor 1) (CRH-R 1).

CALCR_HUMAN
θ value	1.9326e-10 (rank : 159)	NC score	0.435992 (rank : 184)
Query Neighborhood Hits	349	Target Neighborhood Hits	67	Shared Neighborhood Hits	64
SwissProt Accessions	P30988, O14585, Q13941, Q6DJU8, Q6T712	Gene names	CALCR
Domain Architecture
Description	Calcitonin receptor precursor (CT-R).

GLP1R_HUMAN
θ value	1.9326e-10 (rank : 160)	NC score	0.415221 (rank : 198)
Query Neighborhood Hits	349	Target Neighborhood Hits	84	Shared Neighborhood Hits	67
SwissProt Accessions	P43220, Q99669	Gene names	GLP1R
Domain Architecture
Description	Glucagon-like peptide 1 receptor precursor (GLP-1 receptor) (GLP-1-R) (GLP-1R).

DLL3_HUMAN
θ value	3.29651e-10 (rank : 161)	NC score	0.594368 (rank : 104)
Query Neighborhood Hits	349	Target Neighborhood Hits	419	Shared Neighborhood Hits	214
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DLL3_MOUSE
θ value	3.29651e-10 (rank : 162)	NC score	0.605032 (rank : 90)
Query Neighborhood Hits	349	Target Neighborhood Hits	399	Shared Neighborhood Hits	218
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

MATN4_HUMAN
θ value	3.29651e-10 (rank : 163)	NC score	0.580612 (rank : 111)
Query Neighborhood Hits	349	Target Neighborhood Hits	287	Shared Neighborhood Hits	206
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

VIPR2_MOUSE
θ value	3.29651e-10 (rank : 164)	NC score	0.434406 (rank : 186)
Query Neighborhood Hits	349	Target Neighborhood Hits	98	Shared Neighborhood Hits	72
SwissProt Accessions	P41588, P97750	Gene names	Vipr2
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3).

CALCR_MOUSE
θ value	4.30538e-10 (rank : 165)	NC score	0.425972 (rank : 191)
Query Neighborhood Hits	349	Target Neighborhood Hits	76	Shared Neighborhood Hits	68
SwissProt Accessions	Q60755	Gene names	Calcr
Domain Architecture
Description	Calcitonin receptor precursor (CT-R).

CREL1_MOUSE
θ value	5.62301e-10 (rank : 166)	NC score	0.635644 (rank : 72)
Query Neighborhood Hits	349	Target Neighborhood Hits	524	Shared Neighborhood Hits	210
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

GLR_MOUSE
θ value	7.34386e-10 (rank : 167)	NC score	0.391453 (rank : 207)
Query Neighborhood Hits	349	Target Neighborhood Hits	79	Shared Neighborhood Hits	68
SwissProt Accessions	Q61606, Q63960	Gene names	Gcgr
Domain Architecture
Description	Glucagon receptor precursor (GL-R).

LDLR_MOUSE
θ value	7.34386e-10 (rank : 168)	NC score	0.487567 (rank : 150)
Query Neighborhood Hits	349	Target Neighborhood Hits	382	Shared Neighborhood Hits	229
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

GLR_HUMAN
θ value	9.59137e-10 (rank : 169)	NC score	0.400065 (rank : 203)
Query Neighborhood Hits	349	Target Neighborhood Hits	77	Shared Neighborhood Hits	69
SwissProt Accessions	P47871	Gene names	GCGR
Domain Architecture
Description	Glucagon receptor precursor (GL-R).

PACR_MOUSE
θ value	9.59137e-10 (rank : 170)	NC score	0.436577 (rank : 183)
Query Neighborhood Hits	349	Target Neighborhood Hits	83	Shared Neighborhood Hits	74
SwissProt Accessions	P70205	Gene names	Adcyap1r1
Domain Architecture
Description	Pituitary adenylate cyclase-activating polypeptide type I receptor precursor (PACAP type I receptor) (PACAP-R-1).

MATN3_MOUSE
θ value	1.25267e-09 (rank : 171)	NC score	0.574753 (rank : 114)
Query Neighborhood Hits	349	Target Neighborhood Hits	261	Shared Neighborhood Hits	195
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

LRP8_MOUSE
θ value	1.63604e-09 (rank : 172)	NC score	0.492348 (rank : 149)
Query Neighborhood Hits	349	Target Neighborhood Hits	385	Shared Neighborhood Hits	221
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

PTHR1_MOUSE
θ value	1.63604e-09 (rank : 173)	NC score	0.411092 (rank : 199)
Query Neighborhood Hits	349	Target Neighborhood Hits	90	Shared Neighborhood Hits	72
SwissProt Accessions	P41593, Q62119	Gene names	Pthr1, Pthr
Domain Architecture
Description	Parathyroid hormone/parathyroid hormone-related peptide receptor precursor (PTH/PTHr receptor) (PTH/PTHrP type I receptor).

GHRHR_HUMAN
θ value	3.64472e-09 (rank : 174)	NC score	0.408451 (rank : 200)
Query Neighborhood Hits	349	Target Neighborhood Hits	78	Shared Neighborhood Hits	72
SwissProt Accessions	Q02643, Q99863	Gene names	GHRHR
Domain Architecture
Description	Growth hormone-releasing hormone receptor precursor (GHRH receptor) (GRF receptor) (GRFR).

LRP1B_MOUSE
θ value	3.64472e-09 (rank : 175)	NC score	0.514212 (rank : 135)
Query Neighborhood Hits	349	Target Neighborhood Hits	606	Shared Neighborhood Hits	261
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1B_HUMAN
θ value	4.76016e-09 (rank : 176)	NC score	0.513193 (rank : 137)
Query Neighborhood Hits	349	Target Neighborhood Hits	602	Shared Neighborhood Hits	260
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

GHRHR_MOUSE
θ value	6.21693e-09 (rank : 177)	NC score	0.385531 (rank : 210)
Query Neighborhood Hits	349	Target Neighborhood Hits	79	Shared Neighborhood Hits	71
SwissProt Accessions	P32082	Gene names	Ghrhr, Grfr
Domain Architecture	No domain graphic available
Description	Growth hormone-releasing hormone receptor precursor (GHRH receptor) (GRF receptor) (GRFR).

MATN3_HUMAN
θ value	8.11959e-09 (rank : 178)	NC score	0.572401 (rank : 118)
Query Neighborhood Hits	349	Target Neighborhood Hits	268	Shared Neighborhood Hits	195
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

LDLR_HUMAN
θ value	1.06045e-08 (rank : 179)	NC score	0.508868 (rank : 142)
Query Neighborhood Hits	349	Target Neighborhood Hits	375	Shared Neighborhood Hits	227
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

MATN4_MOUSE
θ value	1.38499e-08 (rank : 180)	NC score	0.547110 (rank : 129)
Query Neighborhood Hits	349	Target Neighborhood Hits	277	Shared Neighborhood Hits	205
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

DLK_HUMAN
θ value	1.80886e-08 (rank : 181)	NC score	0.602956 (rank : 94)
Query Neighborhood Hits	349	Target Neighborhood Hits	401	Shared Neighborhood Hits	216
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

FATH_HUMAN
θ value	3.08544e-08 (rank : 182)	NC score	0.344341 (rank : 223)
Query Neighborhood Hits	349	Target Neighborhood Hits	570	Shared Neighborhood Hits	222
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

TSP2_MOUSE
θ value	4.0297e-08 (rank : 183)	NC score	0.432835 (rank : 187)
Query Neighborhood Hits	349	Target Neighborhood Hits	352	Shared Neighborhood Hits	174
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

ZAN_MOUSE
θ value	6.87365e-08 (rank : 184)	NC score	0.428392 (rank : 190)
Query Neighborhood Hits	349	Target Neighborhood Hits	808	Shared Neighborhood Hits	227
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

DLK_MOUSE
θ value	8.97725e-08 (rank : 185)	NC score	0.604717 (rank : 91)
Query Neighborhood Hits	349	Target Neighborhood Hits	374	Shared Neighborhood Hits	216
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

GLP2R_HUMAN
θ value	1.17247e-07 (rank : 186)	NC score	0.371576 (rank : 218)
Query Neighborhood Hits	349	Target Neighborhood Hits	75	Shared Neighborhood Hits	69
SwissProt Accessions	O95838	Gene names	GLP2R
Domain Architecture
Description	Glucagon-like peptide 2 receptor precursor (GLP-2 receptor) (GLP-2-R) (GLP-2R).

EGFL9_MOUSE
θ value	1.53129e-07 (rank : 187)	NC score	0.601483 (rank : 97)
Query Neighborhood Hits	349	Target Neighborhood Hits	379	Shared Neighborhood Hits	220
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

LRP8_HUMAN
θ value	1.53129e-07 (rank : 188)	NC score	0.487000 (rank : 151)
Query Neighborhood Hits	349	Target Neighborhood Hits	346	Shared Neighborhood Hits	213
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

EGFL9_HUMAN
θ value	1.99992e-07 (rank : 189)	NC score	0.598613 (rank : 100)
Query Neighborhood Hits	349	Target Neighborhood Hits	365	Shared Neighborhood Hits	219
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

TSP1_HUMAN
θ value	1.99992e-07 (rank : 190)	NC score	0.467247 (rank : 167)
Query Neighborhood Hits	349	Target Neighborhood Hits	389	Shared Neighborhood Hits	191
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_MOUSE
θ value	2.61198e-07 (rank : 191)	NC score	0.470243 (rank : 163)
Query Neighborhood Hits	349	Target Neighborhood Hits	396	Shared Neighborhood Hits	195
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

GIPR_HUMAN
θ value	3.41135e-07 (rank : 192)	NC score	0.382271 (rank : 214)
Query Neighborhood Hits	349	Target Neighborhood Hits	71	Shared Neighborhood Hits	68
SwissProt Accessions	P48546, Q14401, Q16400, Q9UPI1	Gene names	GIPR
Domain Architecture
Description	Gastric inhibitory polypeptide receptor precursor (GIP-R) (Glucose- dependent insulinotropic polypeptide receptor).

VLDLR_HUMAN
θ value	7.59969e-07 (rank : 193)	NC score	0.495526 (rank : 148)
Query Neighborhood Hits	349	Target Neighborhood Hits	383	Shared Neighborhood Hits	228
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
θ value	7.59969e-07 (rank : 194)	NC score	0.498966 (rank : 146)
Query Neighborhood Hits	349	Target Neighborhood Hits	360	Shared Neighborhood Hits	227
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

GP123_HUMAN
θ value	9.92553e-07 (rank : 195)	NC score	0.395120 (rank : 206)
Query Neighborhood Hits	349	Target Neighborhood Hits	120	Shared Neighborhood Hits	49
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

LRP4_HUMAN
θ value	3.77169e-06 (rank : 196)	NC score	0.460862 (rank : 171)
Query Neighborhood Hits	349	Target Neighborhood Hits	355	Shared Neighborhood Hits	226
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP4_MOUSE
θ value	3.77169e-06 (rank : 197)	NC score	0.465119 (rank : 169)
Query Neighborhood Hits	349	Target Neighborhood Hits	351	Shared Neighborhood Hits	226
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

TSP2_HUMAN
θ value	8.40245e-06 (rank : 198)	NC score	0.443700 (rank : 181)
Query Neighborhood Hits	349	Target Neighborhood Hits	359	Shared Neighborhood Hits	175
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

EDIL3_HUMAN
θ value	3.19293e-05 (rank : 199)	NC score	0.458115 (rank : 174)
Query Neighborhood Hits	349	Target Neighborhood Hits	292	Shared Neighborhood Hits	192
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

LYAM2_HUMAN
θ value	3.19293e-05 (rank : 200)	NC score	0.294688 (rank : 253)
Query Neighborhood Hits	349	Target Neighborhood Hits	394	Shared Neighborhood Hits	185
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM3_HUMAN
θ value	5.44631e-05 (rank : 201)	NC score	0.287722 (rank : 257)
Query Neighborhood Hits	349	Target Neighborhood Hits	378	Shared Neighborhood Hits	188
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

CD248_HUMAN
θ value	7.1131e-05 (rank : 202)	NC score	0.542021 (rank : 131)
Query Neighborhood Hits	349	Target Neighborhood Hits	679	Shared Neighborhood Hits	206
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

EDIL3_MOUSE
θ value	0.000158464 (rank : 203)	NC score	0.450321 (rank : 177)
Query Neighborhood Hits	349	Target Neighborhood Hits	317	Shared Neighborhood Hits	199
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

LYAM3_MOUSE
θ value	0.000158464 (rank : 204)	NC score	0.321282 (rank : 234)
Query Neighborhood Hits	349	Target Neighborhood Hits	390	Shared Neighborhood Hits	196
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

CD248_MOUSE
θ value	0.000270298 (rank : 205)	NC score	0.560279 (rank : 127)
Query Neighborhood Hits	349	Target Neighborhood Hits	578	Shared Neighborhood Hits	203
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

MEGF8_MOUSE
θ value	0.00035302 (rank : 206)	NC score	0.485802 (rank : 154)
Query Neighborhood Hits	349	Target Neighborhood Hits	520	Shared Neighborhood Hits	224
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

BMP1_HUMAN
θ value	0.000461057 (rank : 207)	NC score	0.294283 (rank : 254)
Query Neighborhood Hits	349	Target Neighborhood Hits	233	Shared Neighborhood Hits	171
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

MEGF8_HUMAN
θ value	0.000461057 (rank : 208)	NC score	0.485059 (rank : 155)
Query Neighborhood Hits	349	Target Neighborhood Hits	528	Shared Neighborhood Hits	228
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

BMP1_MOUSE
θ value	0.000786445 (rank : 209)	NC score	0.296525 (rank : 250)
Query Neighborhood Hits	349	Target Neighborhood Hits	236	Shared Neighborhood Hits	172
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

CSPG3_HUMAN
θ value	0.00102713 (rank : 210)	NC score	0.358719 (rank : 222)
Query Neighborhood Hits	349	Target Neighborhood Hits	676	Shared Neighborhood Hits	188
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

PROZ_MOUSE
θ value	0.00102713 (rank : 211)	NC score	0.457022 (rank : 175)
Query Neighborhood Hits	349	Target Neighborhood Hits	410	Shared Neighborhood Hits	212
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

CSPG3_MOUSE
θ value	0.00134147 (rank : 212)	NC score	0.363945 (rank : 221)
Query Neighborhood Hits	349	Target Neighborhood Hits	657	Shared Neighborhood Hits	193
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

GRN_HUMAN
θ value	0.00134147 (rank : 213)	NC score	0.381345 (rank : 215)
Query Neighborhood Hits	349	Target Neighborhood Hits	268	Shared Neighborhood Hits	133
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

UROL1_HUMAN
θ value	0.00134147 (rank : 214)	NC score	0.301833 (rank : 244)
Query Neighborhood Hits	349	Target Neighborhood Hits	213	Shared Neighborhood Hits	130
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

ADA18_MOUSE
θ value	0.00175202 (rank : 215)	NC score	0.077512 (rank : 517)
Query Neighborhood Hits	349	Target Neighborhood Hits	227	Shared Neighborhood Hits	90
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

CSPG2_HUMAN
θ value	0.00175202 (rank : 216)	NC score	0.376299 (rank : 217)
Query Neighborhood Hits	349	Target Neighborhood Hits	681	Shared Neighborhood Hits	192
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CSPG2_MOUSE
θ value	0.00228821 (rank : 217)	NC score	0.380533 (rank : 216)
Query Neighborhood Hits	349	Target Neighborhood Hits	711	Shared Neighborhood Hits	196
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

EGFL8_MOUSE
θ value	0.00228821 (rank : 218)	NC score	0.578860 (rank : 112)
Query Neighborhood Hits	349	Target Neighborhood Hits	266	Shared Neighborhood Hits	198
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

LAMC2_HUMAN
θ value	0.00228821 (rank : 219)	NC score	0.269532 (rank : 276)
Query Neighborhood Hits	349	Target Neighborhood Hits	715	Shared Neighborhood Hits	176
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

PROC_HUMAN
θ value	0.00228821 (rank : 220)	NC score	0.216280 (rank : 334)
Query Neighborhood Hits	349	Target Neighborhood Hits	406	Shared Neighborhood Hits	195
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

FA10_MOUSE
θ value	0.00298849 (rank : 221)	NC score	0.255015 (rank : 288)
Query Neighborhood Hits	349	Target Neighborhood Hits	435	Shared Neighborhood Hits	218
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

PERT_MOUSE
θ value	0.00298849 (rank : 222)	NC score	0.325816 (rank : 230)
Query Neighborhood Hits	349	Target Neighborhood Hits	221	Shared Neighborhood Hits	156
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

EGFL7_HUMAN
θ value	0.00390308 (rank : 223)	NC score	0.607612 (rank : 84)
Query Neighborhood Hits	349	Target Neighborhood Hits	325	Shared Neighborhood Hits	213
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

LYAM2_MOUSE
θ value	0.00390308 (rank : 224)	NC score	0.279976 (rank : 265)
Query Neighborhood Hits	349	Target Neighborhood Hits	420	Shared Neighborhood Hits	192
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

FA10_HUMAN
θ value	0.00509761 (rank : 225)	NC score	0.249531 (rank : 293)
Query Neighborhood Hits	349	Target Neighborhood Hits	431	Shared Neighborhood Hits	215
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

PROZ_HUMAN
θ value	0.00509761 (rank : 226)	NC score	0.453252 (rank : 176)
Query Neighborhood Hits	349	Target Neighborhood Hits	422	Shared Neighborhood Hits	224
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

CORIN_HUMAN
θ value	0.00665767 (rank : 227)	NC score	0.139233 (rank : 412)
Query Neighborhood Hits	349	Target Neighborhood Hits	453	Shared Neighborhood Hits	164
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

ITB2_HUMAN
θ value	0.00665767 (rank : 228)	NC score	0.227640 (rank : 322)
Query Neighborhood Hits	349	Target Neighborhood Hits	282	Shared Neighborhood Hits	153
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

SREC2_HUMAN
θ value	0.00665767 (rank : 229)	NC score	0.450046 (rank : 178)
Query Neighborhood Hits	349	Target Neighborhood Hits	645	Shared Neighborhood Hits	216
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

TLL1_MOUSE
θ value	0.00665767 (rank : 230)	NC score	0.284877 (rank : 260)
Query Neighborhood Hits	349	Target Neighborhood Hits	237	Shared Neighborhood Hits	173
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

EGFL7_MOUSE
θ value	0.00869519 (rank : 231)	NC score	0.593079 (rank : 105)
Query Neighborhood Hits	349	Target Neighborhood Hits	287	Shared Neighborhood Hits	197
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

LAMC2_MOUSE
θ value	0.00869519 (rank : 232)	NC score	0.292378 (rank : 255)
Query Neighborhood Hits	349	Target Neighborhood Hits	614	Shared Neighborhood Hits	182
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

GRN_MOUSE
θ value	0.0113563 (rank : 233)	NC score	0.398500 (rank : 204)
Query Neighborhood Hits	349	Target Neighborhood Hits	248	Shared Neighborhood Hits	133
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

TLL1_HUMAN
θ value	0.0148317 (rank : 234)	NC score	0.277576 (rank : 267)
Query Neighborhood Hits	349	Target Neighborhood Hits	236	Shared Neighborhood Hits	170
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

ITB5_HUMAN
θ value	0.0193708 (rank : 235)	NC score	0.275869 (rank : 268)
Query Neighborhood Hits	349	Target Neighborhood Hits	310	Shared Neighborhood Hits	179
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

EGFL8_HUMAN
θ value	0.0252991 (rank : 236)	NC score	0.573883 (rank : 117)
Query Neighborhood Hits	349	Target Neighborhood Hits	270	Shared Neighborhood Hits	199
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

FRAS1_HUMAN
θ value	0.0330416 (rank : 237)	NC score	0.260579 (rank : 284)
Query Neighborhood Hits	349	Target Neighborhood Hits	759	Shared Neighborhood Hits	181
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

C1RA_MOUSE
θ value	0.0431538 (rank : 238)	NC score	0.161261 (rank : 383)
Query Neighborhood Hits	349	Target Neighborhood Hits	379	Shared Neighborhood Hits	159
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1RB_MOUSE
θ value	0.0431538 (rank : 239)	NC score	0.159070 (rank : 385)
Query Neighborhood Hits	349	Target Neighborhood Hits	380	Shared Neighborhood Hits	159
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

C1S_HUMAN
θ value	0.0431538 (rank : 240)	NC score	0.131996 (rank : 424)
Query Neighborhood Hits	349	Target Neighborhood Hits	359	Shared Neighborhood Hits	145
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

LAMC1_HUMAN
θ value	0.0431538 (rank : 241)	NC score	0.266239 (rank : 279)
Query Neighborhood Hits	349	Target Neighborhood Hits	922	Shared Neighborhood Hits	189
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

SREC2_MOUSE
θ value	0.0431538 (rank : 242)	NC score	0.459104 (rank : 173)
Query Neighborhood Hits	349	Target Neighborhood Hits	605	Shared Neighborhood Hits	221
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

CS1B_MOUSE
θ value	0.0563607 (rank : 243)	NC score	0.136323 (rank : 419)
Query Neighborhood Hits	349	Target Neighborhood Hits	361	Shared Neighborhood Hits	140
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

MASP2_MOUSE
θ value	0.0563607 (rank : 244)	NC score	0.134856 (rank : 420)
Query Neighborhood Hits	349	Target Neighborhood Hits	382	Shared Neighborhood Hits	150
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

ST14_HUMAN
θ value	0.0563607 (rank : 245)	NC score	0.122168 (rank : 439)
Query Neighborhood Hits	349	Target Neighborhood Hits	409	Shared Neighborhood Hits	143
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

ITB2_MOUSE
θ value	0.0736092 (rank : 246)	NC score	0.244919 (rank : 296)
Query Neighborhood Hits	349	Target Neighborhood Hits	326	Shared Neighborhood Hits	176
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ST14_MOUSE
θ value	0.0736092 (rank : 247)	NC score	0.124197 (rank : 436)
Query Neighborhood Hits	349	Target Neighborhood Hits	419	Shared Neighborhood Hits	144
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

TLL2_MOUSE
θ value	0.0961366 (rank : 248)	NC score	0.278986 (rank : 266)
Query Neighborhood Hits	349	Target Neighborhood Hits	240	Shared Neighborhood Hits	173
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

CNTP3_HUMAN
θ value	0.125558 (rank : 249)	NC score	0.144280 (rank : 407)
Query Neighborhood Hits	349	Target Neighborhood Hits	195	Shared Neighborhood Hits	99
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

CS1A_MOUSE
θ value	0.125558 (rank : 250)	NC score	0.137282 (rank : 416)
Query Neighborhood Hits	349	Target Neighborhood Hits	360	Shared Neighborhood Hits	140
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

LAMC3_MOUSE
θ value	0.125558 (rank : 251)	NC score	0.297763 (rank : 247)
Query Neighborhood Hits	349	Target Neighborhood Hits	624	Shared Neighborhood Hits	187
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

TLL2_HUMAN
θ value	0.125558 (rank : 252)	NC score	0.281088 (rank : 263)
Query Neighborhood Hits	349	Target Neighborhood Hits	241	Shared Neighborhood Hits	173
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

ADM1A_MOUSE
θ value	0.163984 (rank : 253)	NC score	0.065146 (rank : 559)
Query Neighborhood Hits	349	Target Neighborhood Hits	230	Shared Neighborhood Hits	100
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

TENX_HUMAN
θ value	0.163984 (rank : 254)	NC score	0.382815 (rank : 213)
Query Neighborhood Hits	349	Target Neighborhood Hits	789	Shared Neighborhood Hits	222
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

UROL1_MOUSE
θ value	0.163984 (rank : 255)	NC score	0.316498 (rank : 238)
Query Neighborhood Hits	349	Target Neighborhood Hits	235	Shared Neighborhood Hits	139
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

MASP2_HUMAN
θ value	0.21417 (rank : 256)	NC score	0.136413 (rank : 418)
Query Neighborhood Hits	349	Target Neighborhood Hits	364	Shared Neighborhood Hits	143
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

PROC_MOUSE
θ value	0.21417 (rank : 257)	NC score	0.231300 (rank : 317)
Query Neighborhood Hits	349	Target Neighborhood Hits	426	Shared Neighborhood Hits	201
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

SREC_HUMAN
θ value	0.21417 (rank : 258)	NC score	0.472101 (rank : 161)
Query Neighborhood Hits	349	Target Neighborhood Hits	645	Shared Neighborhood Hits	219
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

ADA10_HUMAN
θ value	0.279714 (rank : 259)	NC score	0.087405 (rank : 495)
Query Neighborhood Hits	349	Target Neighborhood Hits	189	Shared Neighborhood Hits	72
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

FZD3_HUMAN
θ value	0.279714 (rank : 260)	NC score	0.042179 (rank : 650)
Query Neighborhood Hits	349	Target Neighborhood Hits	74	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NPG1	Gene names	FZD3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (hFz3).

LAMB1_HUMAN
θ value	0.279714 (rank : 261)	NC score	0.256629 (rank : 287)
Query Neighborhood Hits	349	Target Neighborhood Hits	1018	Shared Neighborhood Hits	189
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

VEGFC_MOUSE
θ value	0.279714 (rank : 262)	NC score	0.095906 (rank : 473)
Query Neighborhood Hits	349	Target Neighborhood Hits	119	Shared Neighborhood Hits	69
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

FZD3_MOUSE
θ value	0.365318 (rank : 263)	NC score	0.041542 (rank : 651)
Query Neighborhood Hits	349	Target Neighborhood Hits	75	Shared Neighborhood Hits	22
SwissProt Accessions	Q61086	Gene names	Fzd3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (mFz3).

ITB3_HUMAN
θ value	0.365318 (rank : 264)	NC score	0.262161 (rank : 283)
Query Neighborhood Hits	349	Target Neighborhood Hits	325	Shared Neighborhood Hits	184
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

MUC13_MOUSE
θ value	0.365318 (rank : 265)	NC score	0.229422 (rank : 319)
Query Neighborhood Hits	349	Target Neighborhood Hits	447	Shared Neighborhood Hits	140
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

PERT_HUMAN
θ value	0.365318 (rank : 266)	NC score	0.339885 (rank : 225)
Query Neighborhood Hits	349	Target Neighborhood Hits	221	Shared Neighborhood Hits	160
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

ZAN_HUMAN
θ value	0.365318 (rank : 267)	NC score	0.245180 (rank : 295)
Query Neighborhood Hits	349	Target Neighborhood Hits	679	Shared Neighborhood Hits	194
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

AGRIN_HUMAN
θ value	0.47712 (rank : 268)	NC score	0.395162 (rank : 205)
Query Neighborhood Hits	349	Target Neighborhood Hits	582	Shared Neighborhood Hits	219
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

CLC14_HUMAN
θ value	0.47712 (rank : 269)	NC score	0.269222 (rank : 277)
Query Neighborhood Hits	349	Target Neighborhood Hits	143	Shared Neighborhood Hits	114
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

FA9_HUMAN
θ value	0.47712 (rank : 270)	NC score	0.230251 (rank : 318)
Query Neighborhood Hits	349	Target Neighborhood Hits	421	Shared Neighborhood Hits	207
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

KR106_HUMAN
θ value	0.47712 (rank : 271)	NC score	0.340049 (rank : 224)
Query Neighborhood Hits	349	Target Neighborhood Hits	347	Shared Neighborhood Hits	155
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

LRP5_HUMAN
θ value	0.47712 (rank : 272)	NC score	0.223509 (rank : 324)
Query Neighborhood Hits	349	Target Neighborhood Hits	224	Shared Neighborhood Hits	133
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LRP5_MOUSE
θ value	0.47712 (rank : 273)	NC score	0.229417 (rank : 320)
Query Neighborhood Hits	349	Target Neighborhood Hits	236	Shared Neighborhood Hits	135
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

MASP1_HUMAN
θ value	0.47712 (rank : 274)	NC score	0.131204 (rank : 425)
Query Neighborhood Hits	349	Target Neighborhood Hits	369	Shared Neighborhood Hits	144
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

MUC13_HUMAN
θ value	0.47712 (rank : 275)	NC score	0.147559 (rank : 404)
Query Neighborhood Hits	349	Target Neighborhood Hits	164	Shared Neighborhood Hits	84
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

PCSK5_MOUSE
θ value	0.47712 (rank : 276)	NC score	0.298254 (rank : 245)
Query Neighborhood Hits	349	Target Neighborhood Hits	613	Shared Neighborhood Hits	199
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

VEGFC_HUMAN
θ value	0.47712 (rank : 277)	NC score	0.093549 (rank : 480)
Query Neighborhood Hits	349	Target Neighborhood Hits	128	Shared Neighborhood Hits	71
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

GP143_MOUSE
θ value	0.62314 (rank : 278)	NC score	0.030264 (rank : 655)
Query Neighborhood Hits	349	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	P70259, O89031	Gene names	Gpr143, Oa1
Domain Architecture
Description	G-protein coupled receptor 143 (Ocular albinism type 1 protein homolog) (MOA1).

LAMB1_MOUSE
θ value	0.62314 (rank : 279)	NC score	0.264725 (rank : 281)
Query Neighborhood Hits	349	Target Neighborhood Hits	919	Shared Neighborhood Hits	185
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

MASP1_MOUSE
θ value	0.62314 (rank : 280)	NC score	0.128319 (rank : 429)
Query Neighborhood Hits	349	Target Neighborhood Hits	364	Shared Neighborhood Hits	146
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

ADA10_MOUSE
θ value	0.813845 (rank : 281)	NC score	0.082000 (rank : 507)
Query Neighborhood Hits	349	Target Neighborhood Hits	194	Shared Neighborhood Hits	68
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

C1R_HUMAN
θ value	0.813845 (rank : 282)	NC score	0.149121 (rank : 401)
Query Neighborhood Hits	349	Target Neighborhood Hits	364	Shared Neighborhood Hits	148
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

TMPS6_HUMAN
θ value	0.813845 (rank : 283)	NC score	0.084894 (rank : 500)
Query Neighborhood Hits	349	Target Neighborhood Hits	338	Shared Neighborhood Hits	112
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TNR1A_HUMAN
θ value	0.813845 (rank : 284)	NC score	0.044153 (rank : 648)
Query Neighborhood Hits	349	Target Neighborhood Hits	121	Shared Neighborhood Hits	32
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

WNT8A_HUMAN
θ value	0.813845 (rank : 285)	NC score	0.001208 (rank : 669)
Query Neighborhood Hits	349	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H1J5, Q96S51	Gene names	WNT8A, WNT8D
Domain Architecture
Description	Protein Wnt-8a precursor (Wnt-8d).

ADA18_HUMAN
θ value	1.06291 (rank : 286)	NC score	0.067755 (rank : 543)
Query Neighborhood Hits	349	Target Neighborhood Hits	184	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

FA7_HUMAN
θ value	1.06291 (rank : 287)	NC score	0.215460 (rank : 335)
Query Neighborhood Hits	349	Target Neighborhood Hits	404	Shared Neighborhood Hits	198
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

GP141_HUMAN
θ value	1.06291 (rank : 288)	NC score	-0.001934 (rank : 672)
Query Neighborhood Hits	349	Target Neighborhood Hits	301	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z602, Q86SP3	Gene names	GPR141, PGR13
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 141 (G-protein coupled receptor PGR13).

LAMA5_MOUSE
θ value	1.06291 (rank : 289)	NC score	0.323110 (rank : 232)
Query Neighborhood Hits	349	Target Neighborhood Hits	828	Shared Neighborhood Hits	213
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

TMPS6_MOUSE
θ value	1.06291 (rank : 290)	NC score	0.083431 (rank : 505)
Query Neighborhood Hits	349	Target Neighborhood Hits	341	Shared Neighborhood Hits	114
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

CRAC1_HUMAN
θ value	1.38821 (rank : 291)	NC score	0.364924 (rank : 219)
Query Neighborhood Hits	349	Target Neighborhood Hits	111	Shared Neighborhood Hits	98
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRAC1_MOUSE
θ value	1.38821 (rank : 292)	NC score	0.364617 (rank : 220)
Query Neighborhood Hits	349	Target Neighborhood Hits	112	Shared Neighborhood Hits	99
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

GP158_MOUSE
θ value	1.38821 (rank : 293)	NC score	0.028959 (rank : 656)
Query Neighborhood Hits	349	Target Neighborhood Hits	82	Shared Neighborhood Hits	18
SwissProt Accessions	Q8C419, Q8CHB0	Gene names	Gpr158, Kiaa1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

ITB1_HUMAN
θ value	1.38821 (rank : 294)	NC score	0.221040 (rank : 328)
Query Neighborhood Hits	349	Target Neighborhood Hits	298	Shared Neighborhood Hits	153
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB4_HUMAN
θ value	1.38821 (rank : 295)	NC score	0.234757 (rank : 314)
Query Neighborhood Hits	349	Target Neighborhood Hits	458	Shared Neighborhood Hits	162
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

LAMA2_HUMAN
θ value	1.38821 (rank : 296)	NC score	0.271704 (rank : 273)
Query Neighborhood Hits	349	Target Neighborhood Hits	1092	Shared Neighborhood Hits	198
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMC1_MOUSE
θ value	1.38821 (rank : 297)	NC score	0.269907 (rank : 275)
Query Neighborhood Hits	349	Target Neighborhood Hits	856	Shared Neighborhood Hits	189
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LYAM1_HUMAN
θ value	1.38821 (rank : 298)	NC score	0.220794 (rank : 329)
Query Neighborhood Hits	349	Target Neighborhood Hits	315	Shared Neighborhood Hits	147
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM1_MOUSE
θ value	1.38821 (rank : 299)	NC score	0.213219 (rank : 337)
Query Neighborhood Hits	349	Target Neighborhood Hits	332	Shared Neighborhood Hits	151
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

MATN1_HUMAN
θ value	1.38821 (rank : 300)	NC score	0.244328 (rank : 298)
Query Neighborhood Hits	349	Target Neighborhood Hits	191	Shared Neighborhood Hits	138
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

PGBM_HUMAN
θ value	1.38821 (rank : 301)	NC score	0.254939 (rank : 289)
Query Neighborhood Hits	349	Target Neighborhood Hits	1113	Shared Neighborhood Hits	226
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

RAI3_MOUSE
θ value	1.38821 (rank : 302)	NC score	0.008296 (rank : 659)
Query Neighborhood Hits	349	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHL4, Q8K067, Q8K1G5	Gene names	Gprc5a, Rai3, Raig1
Domain Architecture
Description	Retinoic acid-induced protein 3 (G-protein coupled receptor family C group 5 member A) (Retinoic acid-induced gene 1 protein) (RAIG-1).

ENTK_MOUSE
θ value	1.81305 (rank : 303)	NC score	0.043667 (rank : 649)
Query Neighborhood Hits	349	Target Neighborhood Hits	338	Shared Neighborhood Hits	66
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

PGBM_MOUSE
θ value	1.81305 (rank : 304)	NC score	0.256945 (rank : 286)
Query Neighborhood Hits	349	Target Neighborhood Hits	1073	Shared Neighborhood Hits	223
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

TIE2_MOUSE
θ value	1.81305 (rank : 305)	NC score	0.095615 (rank : 474)
Query Neighborhood Hits	349	Target Neighborhood Hits	1204	Shared Neighborhood Hits	176
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

YIPF1_HUMAN
θ value	1.81305 (rank : 306)	NC score	0.009265 (rank : 658)
Query Neighborhood Hits	349	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y548, Q9NWJ1	Gene names	YIPF1
Domain Architecture	No domain graphic available
Description	Protein YIPF1 (YIP1 family member 1).

ATS12_MOUSE
θ value	2.36792 (rank : 307)	NC score	0.037008 (rank : 652)
Query Neighborhood Hits	349	Target Neighborhood Hits	220	Shared Neighborhood Hits	30
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

LAMA1_MOUSE
θ value	2.36792 (rank : 308)	NC score	0.298241 (rank : 246)
Query Neighborhood Hits	349	Target Neighborhood Hits	838	Shared Neighborhood Hits	209
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

NALP4_HUMAN
θ value	2.36792 (rank : 309)	NC score	0.000938 (rank : 670)
Query Neighborhood Hits	349	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	Q96MN2, Q86W87, Q96AY6	Gene names	NALP4, PAN2, PYPAF4, RNH2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 4 (PYRIN-containing APAF1-like protein 4) (PAAD and NACHT-containing protein 2) (PYRIN and NACHT- containing protein 2) (Ribonuclease inhibitor 2).

SORL_HUMAN
θ value	2.36792 (rank : 310)	NC score	0.274554 (rank : 269)
Query Neighborhood Hits	349	Target Neighborhood Hits	440	Shared Neighborhood Hits	162
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

TEFF2_HUMAN
θ value	2.36792 (rank : 311)	NC score	0.185639 (rank : 356)
Query Neighborhood Hits	349	Target Neighborhood Hits	211	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

ARP5_HUMAN
θ value	3.0926 (rank : 312)	NC score	0.002952 (rank : 664)
Query Neighborhood Hits	349	Target Neighborhood Hits	107	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H9F9, Q86WF7, Q8IUY5, Q8N724, Q9BRN0, Q9BVB7	Gene names	ACTR5, ARP5
Domain Architecture	No domain graphic available
Description	Actin-related protein 5 (hARP5) (Sarcoma antigen NY-SAR-16).

CLC14_MOUSE
θ value	3.0926 (rank : 313)	NC score	0.280093 (rank : 264)
Query Neighborhood Hits	349	Target Neighborhood Hits	120	Shared Neighborhood Hits	110
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

ITB5_MOUSE
θ value	3.0926 (rank : 314)	NC score	0.286347 (rank : 259)
Query Neighborhood Hits	349	Target Neighborhood Hits	329	Shared Neighborhood Hits	185
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

ADA32_HUMAN
θ value	4.03905 (rank : 315)	NC score	0.053505 (rank : 627)
Query Neighborhood Hits	349	Target Neighborhood Hits	216	Shared Neighborhood Hits	99
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

GP143_HUMAN
θ value	4.03905 (rank : 316)	NC score	0.035884 (rank : 653)
Query Neighborhood Hits	349	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	P51810	Gene names	GPR143, OA1
Domain Architecture
Description	G-protein coupled receptor 143 (Ocular albinism type 1 protein).

KR104_HUMAN
θ value	4.03905 (rank : 317)	NC score	0.331624 (rank : 228)
Query Neighborhood Hits	349	Target Neighborhood Hits	313	Shared Neighborhood Hits	145
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

MATN1_MOUSE
θ value	4.03905 (rank : 318)	NC score	0.243689 (rank : 299)
Query Neighborhood Hits	349	Target Neighborhood Hits	186	Shared Neighborhood Hits	133
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MEP1A_HUMAN
θ value	4.03905 (rank : 319)	NC score	0.160559 (rank : 384)
Query Neighborhood Hits	349	Target Neighborhood Hits	162	Shared Neighborhood Hits	113
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

RTN4_HUMAN
θ value	4.03905 (rank : 320)	NC score	0.003375 (rank : 662)
Query Neighborhood Hits	349	Target Neighborhood Hits	357	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

ADAM9_MOUSE
θ value	5.27518 (rank : 321)	NC score	0.069891 (rank : 528)
Query Neighborhood Hits	349	Target Neighborhood Hits	325	Shared Neighborhood Hits	111
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ASTN_HUMAN
θ value	5.27518 (rank : 322)	NC score	0.166469 (rank : 376)
Query Neighborhood Hits	349	Target Neighborhood Hits	105	Shared Neighborhood Hits	78
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

ASTN_MOUSE
θ value	5.27518 (rank : 323)	NC score	0.158745 (rank : 387)
Query Neighborhood Hits	349	Target Neighborhood Hits	98	Shared Neighborhood Hits	74
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

HGFA_MOUSE
θ value	5.27518 (rank : 324)	NC score	0.168747 (rank : 374)
Query Neighborhood Hits	349	Target Neighborhood Hits	419	Shared Neighborhood Hits	179
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

ITB1_MOUSE
θ value	5.27518 (rank : 325)	NC score	0.236626 (rank : 313)
Query Neighborhood Hits	349	Target Neighborhood Hits	283	Shared Neighborhood Hits	150
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

KR107_HUMAN
θ value	5.27518 (rank : 326)	NC score	0.339306 (rank : 226)
Query Neighborhood Hits	349	Target Neighborhood Hits	330	Shared Neighborhood Hits	147
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

LAMB2_MOUSE
θ value	5.27518 (rank : 327)	NC score	0.296235 (rank : 251)
Query Neighborhood Hits	349	Target Neighborhood Hits	722	Shared Neighborhood Hits	190
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

SSPO_MOUSE
θ value	5.27518 (rank : 328)	NC score	0.309533 (rank : 241)
Query Neighborhood Hits	349	Target Neighborhood Hits	800	Shared Neighborhood Hits	212
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

TECTA_HUMAN
θ value	5.27518 (rank : 329)	NC score	0.164915 (rank : 378)
Query Neighborhood Hits	349	Target Neighborhood Hits	239	Shared Neighborhood Hits	131
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

ATRAP_HUMAN
θ value	6.88961 (rank : 330)	NC score	0.006085 (rank : 660)
Query Neighborhood Hits	349	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q6RW13, Q5SNV4, Q5SNV5, Q96AC0, Q96PL4, Q9NRW9	Gene names	AGTRAP, ATRAP
Domain Architecture	No domain graphic available
Description	Type-1 angiotensin II receptor-associated protein (AT1 receptor- associated protein).

HABP2_MOUSE
θ value	6.88961 (rank : 331)	NC score	0.223095 (rank : 326)
Query Neighborhood Hits	349	Target Neighborhood Hits	445	Shared Neighborhood Hits	190
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HGFA_HUMAN
θ value	6.88961 (rank : 332)	NC score	0.169869 (rank : 372)
Query Neighborhood Hits	349	Target Neighborhood Hits	436	Shared Neighborhood Hits	173
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HTRA4_HUMAN
θ value	6.88961 (rank : 333)	NC score	0.005034 (rank : 661)
Query Neighborhood Hits	349	Target Neighborhood Hits	119	Shared Neighborhood Hits	9
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

KR10C_HUMAN
θ value	6.88961 (rank : 334)	NC score	0.210302 (rank : 340)
Query Neighborhood Hits	349	Target Neighborhood Hits	219	Shared Neighborhood Hits	102
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

LAMA3_MOUSE
θ value	6.88961 (rank : 335)	NC score	0.241167 (rank : 304)
Query Neighborhood Hits	349	Target Neighborhood Hits	859	Shared Neighborhood Hits	203
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

NPCL1_HUMAN
θ value	6.88961 (rank : 336)	NC score	0.002069 (rank : 665)
Query Neighborhood Hits	349	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UHC9, Q6R3Q4, Q9UHC8	Gene names	NPC1L1
Domain Architecture	No domain graphic available
Description	Niemann-Pick C1-like protein 1 precursor.

TNR6_HUMAN
θ value	6.88961 (rank : 337)	NC score	0.035486 (rank : 654)
Query Neighborhood Hits	349	Target Neighborhood Hits	95	Shared Neighborhood Hits	37
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

ARP5_MOUSE
θ value	8.99809 (rank : 338)	NC score	0.001607 (rank : 666)
Query Neighborhood Hits	349	Target Neighborhood Hits	116	Shared Neighborhood Hits	3
SwissProt Accessions	Q80US4, Q8BL26	Gene names	Actr5
Domain Architecture	No domain graphic available
Description	Actin-related protein 5.

BIRC6_HUMAN
θ value	8.99809 (rank : 339)	NC score	0.000772 (rank : 671)
Query Neighborhood Hits	349	Target Neighborhood Hits	161	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).

CHSS1_HUMAN
θ value	8.99809 (rank : 340)	NC score	0.001540 (rank : 667)
Query Neighborhood Hits	349	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q86X52, Q6UX38, Q7LFU5, Q9Y2J5	Gene names	CHSY1, CHSY, CSS1, KIAA0990
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 1 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase 1) (Chondroitin sulfate synthase 1) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II).

CHSS1_MOUSE
θ value	8.99809 (rank : 341)	NC score	0.001539 (rank : 668)
Query Neighborhood Hits	349	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZQ11	Gene names	Chsy1, Kiaa0990
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 1 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase) (Chondroitin sulfate synthase 1) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II).

CKLF6_HUMAN
θ value	8.99809 (rank : 342)	NC score	0.003286 (rank : 663)
Query Neighborhood Hits	349	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NX76	Gene names	CMTM6, CKLFSF6
Domain Architecture
Description	CKLF-like MARVEL transmembrane domain-containing protein 6 (Chemokine- like factor superfamily member 6).

CNTP2_HUMAN
θ value	8.99809 (rank : 343)	NC score	0.150006 (rank : 398)
Query Neighborhood Hits	349	Target Neighborhood Hits	199	Shared Neighborhood Hits	114
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP2_MOUSE
θ value	8.99809 (rank : 344)	NC score	0.153251 (rank : 393)
Query Neighborhood Hits	349	Target Neighborhood Hits	194	Shared Neighborhood Hits	111
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

EPHB4_HUMAN
θ value	8.99809 (rank : 345)	NC score	0.018052 (rank : 657)
Query Neighborhood Hits	349	Target Neighborhood Hits	1056	Shared Neighborhood Hits	103
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

FA7_MOUSE
θ value	8.99809 (rank : 346)	NC score	0.177176 (rank : 363)
Query Neighborhood Hits	349	Target Neighborhood Hits	374	Shared Neighborhood Hits	177
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

MKS3_HUMAN
θ value	8.99809 (rank : 347)	NC score	0.087976 (rank : 494)
Query Neighborhood Hits	349	Target Neighborhood Hits	79	Shared Neighborhood Hits	49
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

TECTA_MOUSE
θ value	8.99809 (rank : 348)	NC score	0.182969 (rank : 357)
Query Neighborhood Hits	349	Target Neighborhood Hits	244	Shared Neighborhood Hits	141
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TEFF2_MOUSE
θ value	8.99809 (rank : 349)	NC score	0.186260 (rank : 354)
Query Neighborhood Hits	349	Target Neighborhood Hits	214	Shared Neighborhood Hits	100
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

ADA11_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.093123 (rank : 481)
Query Neighborhood Hits	349	Target Neighborhood Hits	259	Shared Neighborhood Hits	115
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA11_MOUSE
θ value	θ > 10 (rank : 351)	NC score	0.092478 (rank : 483)
Query Neighborhood Hits	349	Target Neighborhood Hits	263	Shared Neighborhood Hits	116
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA12_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.065725 (rank : 551)
Query Neighborhood Hits	349	Target Neighborhood Hits	224	Shared Neighborhood Hits	98
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA15_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.066195 (rank : 547)
Query Neighborhood Hits	349	Target Neighborhood Hits	288	Shared Neighborhood Hits	113
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

ADA15_MOUSE
θ value	θ > 10 (rank : 354)	NC score	0.079842 (rank : 512)
Query Neighborhood Hits	349	Target Neighborhood Hits	324	Shared Neighborhood Hits	128
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADA17_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.076354 (rank : 520)
Query Neighborhood Hits	349	Target Neighborhood Hits	223	Shared Neighborhood Hits	89
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ADA17_MOUSE
θ value	θ > 10 (rank : 356)	NC score	0.054193 (rank : 623)
Query Neighborhood Hits	349	Target Neighborhood Hits	201	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

ADA19_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.080857 (rank : 510)
Query Neighborhood Hits	349	Target Neighborhood Hits	381	Shared Neighborhood Hits	116
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ADA19_MOUSE
θ value	θ > 10 (rank : 358)	NC score	0.082232 (rank : 506)
Query Neighborhood Hits	349	Target Neighborhood Hits	315	Shared Neighborhood Hits	123
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ADA21_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.057476 (rank : 603)
Query Neighborhood Hits	349	Target Neighborhood Hits	181	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

ADA21_MOUSE
θ value	θ > 10 (rank : 360)	NC score	0.065620 (rank : 552)
Query Neighborhood Hits	349	Target Neighborhood Hits	172	Shared Neighborhood Hits	85
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

ADA22_MOUSE
θ value	θ > 10 (rank : 361)	NC score	0.052970 (rank : 632)
Query Neighborhood Hits	349	Target Neighborhood Hits	225	Shared Neighborhood Hits	82
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ADA23_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.088417 (rank : 492)
Query Neighborhood Hits	349	Target Neighborhood Hits	235	Shared Neighborhood Hits	114
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA23_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.085135 (rank : 499)
Query Neighborhood Hits	349	Target Neighborhood Hits	245	Shared Neighborhood Hits	125
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA28_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.055652 (rank : 615)
Query Neighborhood Hits	349	Target Neighborhood Hits	244	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ADA28_MOUSE
θ value	θ > 10 (rank : 365)	NC score	0.050280 (rank : 647)
Query Neighborhood Hits	349	Target Neighborhood Hits	241	Shared Neighborhood Hits	95
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ADA30_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.067926 (rank : 542)
Query Neighborhood Hits	349	Target Neighborhood Hits	391	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ADA33_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.068014 (rank : 541)
Query Neighborhood Hits	349	Target Neighborhood Hits	264	Shared Neighborhood Hits	103
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA33_MOUSE
θ value	θ > 10 (rank : 368)	NC score	0.061814 (rank : 577)
Query Neighborhood Hits	349	Target Neighborhood Hits	231	Shared Neighborhood Hits	88
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADAM2_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.062294 (rank : 572)
Query Neighborhood Hits	349	Target Neighborhood Hits	175	Shared Neighborhood Hits	78
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

ADAM2_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.058663 (rank : 596)
Query Neighborhood Hits	349	Target Neighborhood Hits	209	Shared Neighborhood Hits	89
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

ADAM7_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.069148 (rank : 532)
Query Neighborhood Hits	349	Target Neighborhood Hits	221	Shared Neighborhood Hits	103
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ADAM7_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.050504 (rank : 646)
Query Neighborhood Hits	349	Target Neighborhood Hits	200	Shared Neighborhood Hits	90
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADAM8_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.077762 (rank : 516)
Query Neighborhood Hits	349	Target Neighborhood Hits	327	Shared Neighborhood Hits	119
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ADAM8_MOUSE
θ value	θ > 10 (rank : 374)	NC score	0.087139 (rank : 496)
Query Neighborhood Hits	349	Target Neighborhood Hits	326	Shared Neighborhood Hits	109
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

ADAM9_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.057944 (rank : 599)
Query Neighborhood Hits	349	Target Neighborhood Hits	243	Shared Neighborhood Hits	97
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

ADM1B_MOUSE
θ value	θ > 10 (rank : 376)	NC score	0.058264 (rank : 598)
Query Neighborhood Hits	349	Target Neighborhood Hits	236	Shared Neighborhood Hits	91
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

APR3_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.103062 (rank : 465)
Query Neighborhood Hits	349	Target Neighborhood Hits	50	Shared Neighborhood Hits	43
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

APR3_MOUSE
θ value	θ > 10 (rank : 378)	NC score	0.109503 (rank : 456)
Query Neighborhood Hits	349	Target Neighborhood Hits	61	Shared Neighborhood Hits	46
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

ATL2_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.062160 (rank : 573)
Query Neighborhood Hits	349	Target Neighborhood Hits	125	Shared Neighborhood Hits	32
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

ATL2_MOUSE
θ value	θ > 10 (rank : 380)	NC score	0.059260 (rank : 589)
Query Neighborhood Hits	349	Target Neighborhood Hits	137	Shared Neighborhood Hits	31
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

ATRN_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.205315 (rank : 345)
Query Neighborhood Hits	349	Target Neighborhood Hits	525	Shared Neighborhood Hits	170
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATRN_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.205329 (rank : 344)
Query Neighborhood Hits	349	Target Neighborhood Hits	519	Shared Neighborhood Hits	167
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

ATS20_MOUSE
θ value	θ > 10 (rank : 383)	NC score	0.051160 (rank : 643)
Query Neighborhood Hits	349	Target Neighborhood Hits	225	Shared Neighborhood Hits	51
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS9_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.051438 (rank : 642)
Query Neighborhood Hits	349	Target Neighborhood Hits	219	Shared Neighborhood Hits	57
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

BMPER_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.110911 (rank : 451)
Query Neighborhood Hits	349	Target Neighborhood Hits	175	Shared Neighborhood Hits	73
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

BMPER_MOUSE
θ value	θ > 10 (rank : 386)	NC score	0.115949 (rank : 443)
Query Neighborhood Hits	349	Target Neighborhood Hits	194	Shared Neighborhood Hits	84
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

BTC_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.059579 (rank : 588)
Query Neighborhood Hits	349	Target Neighborhood Hits	70	Shared Neighborhood Hits	38
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

BTC_MOUSE
θ value	θ > 10 (rank : 388)	NC score	0.073068 (rank : 524)
Query Neighborhood Hits	349	Target Neighborhood Hits	67	Shared Neighborhood Hits	39
SwissProt Accessions	Q05928	Gene names	Btc, Bcn
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

CAD17_MOUSE
θ value	θ > 10 (rank : 389)	NC score	0.050577 (rank : 645)
Query Neighborhood Hits	349	Target Neighborhood Hits	157	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R100	Gene names	Cdh17
Domain Architecture
Description	Cadherin-17 precursor (Liver-intestine-cadherin) (LI-cadherin) (BILL- cadherin) (P130).

CAD23_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.058825 (rank : 595)
Query Neighborhood Hits	349	Target Neighborhood Hits	197	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H251, Q6UWW1, Q9H4K9	Gene names	CDH23, KIAA1774
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

CAD23_MOUSE
θ value	θ > 10 (rank : 391)	NC score	0.058974 (rank : 592)
Query Neighborhood Hits	349	Target Neighborhood Hits	208	Shared Neighborhood Hits	11
SwissProt Accessions	Q99PF4, Q99NH1, Q9D4N9	Gene names	Cdh23
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

CD320_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.106664 (rank : 459)
Query Neighborhood Hits	349	Target Neighborhood Hits	103	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

CFC1_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.257632 (rank : 285)
Query Neighborhood Hits	349	Target Neighborhood Hits	148	Shared Neighborhood Hits	98
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CFC1_MOUSE
θ value	θ > 10 (rank : 394)	NC score	0.244813 (rank : 297)
Query Neighborhood Hits	349	Target Neighborhood Hits	125	Shared Neighborhood Hits	86
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CILP2_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.051099 (rank : 644)
Query Neighborhood Hits	349	Target Neighborhood Hits	307	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

CNTP1_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.128445 (rank : 428)
Query Neighborhood Hits	349	Target Neighborhood Hits	196	Shared Neighborhood Hits	97
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

CNTP1_MOUSE
θ value	θ > 10 (rank : 397)	NC score	0.122207 (rank : 438)
Query Neighborhood Hits	349	Target Neighborhood Hits	183	Shared Neighborhood Hits	91
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

CNTP4_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.138212 (rank : 414)
Query Neighborhood Hits	349	Target Neighborhood Hits	187	Shared Neighborhood Hits	93
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CNTP4_MOUSE
θ value	θ > 10 (rank : 399)	NC score	0.137188 (rank : 417)
Query Neighborhood Hits	349	Target Neighborhood Hits	193	Shared Neighborhood Hits	109
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CO6_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.149561 (rank : 399)
Query Neighborhood Hits	349	Target Neighborhood Hits	331	Shared Neighborhood Hits	132
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CO7_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.145137 (rank : 406)
Query Neighborhood Hits	349	Target Neighborhood Hits	278	Shared Neighborhood Hits	117
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO8A_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.094682 (rank : 476)
Query Neighborhood Hits	349	Target Neighborhood Hits	200	Shared Neighborhood Hits	89
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8A_MOUSE
θ value	θ > 10 (rank : 403)	NC score	0.098474 (rank : 470)
Query Neighborhood Hits	349	Target Neighborhood Hits	182	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8B_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.109970 (rank : 453)
Query Neighborhood Hits	349	Target Neighborhood Hits	199	Shared Neighborhood Hits	81
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO8B_MOUSE
θ value	θ > 10 (rank : 405)	NC score	0.131161 (rank : 426)
Query Neighborhood Hits	349	Target Neighborhood Hits	224	Shared Neighborhood Hits	92
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO9_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.083909 (rank : 502)
Query Neighborhood Hits	349	Target Neighborhood Hits	147	Shared Neighborhood Hits	66
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

CO9_MOUSE
θ value	θ > 10 (rank : 407)	NC score	0.091177 (rank : 489)
Query Neighborhood Hits	349	Target Neighborhood Hits	153	Shared Neighborhood Hits	72
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

CORIN_MOUSE
θ value	θ > 10 (rank : 408)	NC score	0.121555 (rank : 440)
Query Neighborhood Hits	349	Target Neighborhood Hits	451	Shared Neighborhood Hits	156
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

CRDL2_MOUSE
θ value	θ > 10 (rank : 409)	NC score	0.054964 (rank : 621)
Query Neighborhood Hits	349	Target Neighborhood Hits	81	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

CRIM1_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.272442 (rank : 272)
Query Neighborhood Hits	349	Target Neighborhood Hits	362	Shared Neighborhood Hits	127
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

CSMD1_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.068274 (rank : 538)
Query Neighborhood Hits	349	Target Neighborhood Hits	176	Shared Neighborhood Hits	54
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD1_MOUSE
θ value	θ > 10 (rank : 412)	NC score	0.068599 (rank : 537)
Query Neighborhood Hits	349	Target Neighborhood Hits	193	Shared Neighborhood Hits	62
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD2_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.064768 (rank : 561)
Query Neighborhood Hits	349	Target Neighborhood Hits	188	Shared Neighborhood Hits	55
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CSMD3_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.071738 (rank : 526)
Query Neighborhood Hits	349	Target Neighborhood Hits	199	Shared Neighborhood Hits	67
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CTGF_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.051540 (rank : 640)
Query Neighborhood Hits	349	Target Neighborhood Hits	128	Shared Neighborhood Hits	45
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

CU063_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.055523 (rank : 617)
Query Neighborhood Hits	349	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	P58658, Q8IXZ0	Gene names	C21orf63
Domain Architecture
Description	Protein C21orf63 precursor (SUE21).

CU063_MOUSE
θ value	θ > 10 (rank : 417)	NC score	0.054301 (rank : 622)
Query Neighborhood Hits	349	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	P58659	Gene names
Domain Architecture
Description	Protein C21orf63 homolog precursor.

CUZD1_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.069004 (rank : 535)
Query Neighborhood Hits	349	Target Neighborhood Hits	89	Shared Neighborhood Hits	32
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

CUZD1_MOUSE
θ value	θ > 10 (rank : 419)	NC score	0.065533 (rank : 553)
Query Neighborhood Hits	349	Target Neighborhood Hits	91	Shared Neighborhood Hits	30
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

CYR61_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.061437 (rank : 581)
Query Neighborhood Hits	349	Target Neighborhood Hits	159	Shared Neighborhood Hits	59
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

CYR61_MOUSE
θ value	θ > 10 (rank : 421)	NC score	0.059226 (rank : 590)
Query Neighborhood Hits	349	Target Neighborhood Hits	156	Shared Neighborhood Hits	56
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

DCBD1_MOUSE
θ value	θ > 10 (rank : 422)	NC score	0.053359 (rank : 629)
Query Neighborhood Hits	349	Target Neighborhood Hits	89	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DKK3_HUMAN
θ value	θ > 10 (rank : 423)	NC score	0.056000 (rank : 611)
Query Neighborhood Hits	349	Target Neighborhood Hits	74	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UBP4, Q9ULB7	Gene names	DKK3, REIC
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3).

DKK3_MOUSE
θ value	θ > 10 (rank : 424)	NC score	0.064648 (rank : 562)
Query Neighborhood Hits	349	Target Neighborhood Hits	83	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

DMBT1_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.056678 (rank : 608)
Query Neighborhood Hits	349	Target Neighborhood Hits	134	Shared Neighborhood Hits	33
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

EPGN_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.064085 (rank : 564)
Query Neighborhood Hits	349	Target Neighborhood Hits	59	Shared Neighborhood Hits	37
SwissProt Accessions	Q6UW88	Gene names	EPGN
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

EPGN_MOUSE
θ value	θ > 10 (rank : 427)	NC score	0.076966 (rank : 518)
Query Neighborhood Hits	349	Target Neighborhood Hits	63	Shared Neighborhood Hits	40
SwissProt Accessions	Q924X1, Q8CEX5	Gene names	Epgn
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

EREG_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.098170 (rank : 471)
Query Neighborhood Hits	349	Target Neighborhood Hits	73	Shared Neighborhood Hits	47
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

EREG_MOUSE
θ value	θ > 10 (rank : 429)	NC score	0.060895 (rank : 583)
Query Neighborhood Hits	349	Target Neighborhood Hits	65	Shared Neighborhood Hits	37
SwissProt Accessions	Q61521, Q7M0A8	Gene names	Ereg
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

ESM1_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.085761 (rank : 498)
Query Neighborhood Hits	349	Target Neighborhood Hits	110	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

ESM1_MOUSE
θ value	θ > 10 (rank : 431)	NC score	0.062426 (rank : 570)
Query Neighborhood Hits	349	Target Neighborhood Hits	107	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

FA12_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.154333 (rank : 391)
Query Neighborhood Hits	349	Target Neighborhood Hits	425	Shared Neighborhood Hits	169
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

FAT2_HUMAN
θ value	θ > 10 (rank : 433)	NC score	0.201527 (rank : 346)
Query Neighborhood Hits	349	Target Neighborhood Hits	507	Shared Neighborhood Hits	160
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

FRAS1_MOUSE
θ value	θ > 10 (rank : 434)	NC score	0.247970 (rank : 294)
Query Neighborhood Hits	349	Target Neighborhood Hits	747	Shared Neighborhood Hits	170
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FSTL3_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.104014 (rank : 463)
Query Neighborhood Hits	349	Target Neighborhood Hits	162	Shared Neighborhood Hits	68
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL3_MOUSE
θ value	θ > 10 (rank : 436)	NC score	0.097061 (rank : 472)
Query Neighborhood Hits	349	Target Neighborhood Hits	152	Shared Neighborhood Hits	66
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FST_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.069468 (rank : 529)
Query Neighborhood Hits	349	Target Neighborhood Hits	129	Shared Neighborhood Hits	44
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FST_MOUSE
θ value	θ > 10 (rank : 438)	NC score	0.081085 (rank : 508)
Query Neighborhood Hits	349	Target Neighborhood Hits	146	Shared Neighborhood Hits	56
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

GNPTA_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.054132 (rank : 624)
Query Neighborhood Hits	349	Target Neighborhood Hits	43	Shared Neighborhood Hits	9
SwissProt Accessions	Q3T906, Q3ZQK2, Q6IPW5, Q86TQ2, Q96N13, Q9ULL2	Gene names	GNPTAB, GNPTA, KIAA1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

GNPTA_MOUSE
θ value	θ > 10 (rank : 440)	NC score	0.052848 (rank : 633)
Query Neighborhood Hits	349	Target Neighborhood Hits	47	Shared Neighborhood Hits	9
SwissProt Accessions	Q69ZN6, Q3U3K6, Q3US34	Gene names	Gnptab, Gnpta, Kiaa1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

GP157_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.190099 (rank : 351)
Query Neighborhood Hits	349	Target Neighborhood Hits	93	Shared Neighborhood Hits	50
SwissProt Accessions	Q5UAW9, Q8WWB8, Q9HA73	Gene names	GPR157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

GP157_MOUSE
θ value	θ > 10 (rank : 442)	NC score	0.181918 (rank : 359)
Query Neighborhood Hits	349	Target Neighborhood Hits	78	Shared Neighborhood Hits	49
SwissProt Accessions	Q8C206, Q8C224	Gene names	Gpr157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

GP2_HUMAN
θ value	θ > 10 (rank : 443)	NC score	0.056882 (rank : 607)
Query Neighborhood Hits	349	Target Neighborhood Hits	34	Shared Neighborhood Hits	12
SwissProt Accessions	P55259, Q13338, Q9UIF1	Gene names	GP2
Domain Architecture
Description	Pancreatic secretory granule membrane major glycoprotein GP2 precursor (Pancreatic zymogen granule membrane protein GP-2) (ZAP75).

GP2_MOUSE
θ value	θ > 10 (rank : 444)	NC score	0.051675 (rank : 638)
Query Neighborhood Hits	349	Target Neighborhood Hits	29	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D733	Gene names	Gp2
Domain Architecture	No domain graphic available
Description	Pancreatic secretory granule membrane major glycoprotein GP2 precursor (Pancreatic zymogen granule membrane protein GP-2).

HABP2_HUMAN
θ value	θ > 10 (rank : 445)	NC score	0.226469 (rank : 323)
Query Neighborhood Hits	349	Target Neighborhood Hits	431	Shared Neighborhood Hits	187
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HBEGF_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.056323 (rank : 610)
Query Neighborhood Hits	349	Target Neighborhood Hits	61	Shared Neighborhood Hits	40
SwissProt Accessions	Q99075	Gene names	HBEGF, DTR, HEGFL
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF) (Diphtheria toxin receptor) (DT-R).

HHIP_HUMAN
θ value	θ > 10 (rank : 447)	NC score	0.319813 (rank : 236)
Query Neighborhood Hits	349	Target Neighborhood Hits	249	Shared Neighborhood Hits	133
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HHIP_MOUSE
θ value	θ > 10 (rank : 448)	NC score	0.318303 (rank : 237)
Query Neighborhood Hits	349	Target Neighborhood Hits	219	Shared Neighborhood Hits	122
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

IDD_HUMAN
θ value	θ > 10 (rank : 449)	NC score	0.052218 (rank : 634)
Query Neighborhood Hits	349	Target Neighborhood Hits	127	Shared Neighborhood Hits	36
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

ITB3_MOUSE
θ value	θ > 10 (rank : 450)	NC score	0.242921 (rank : 301)
Query Neighborhood Hits	349	Target Neighborhood Hits	319	Shared Neighborhood Hits	177
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB6_HUMAN
θ value	θ > 10 (rank : 451)	NC score	0.265798 (rank : 280)
Query Neighborhood Hits	349	Target Neighborhood Hits	318	Shared Neighborhood Hits	170
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB6_MOUSE
θ value	θ > 10 (rank : 452)	NC score	0.287185 (rank : 258)
Query Neighborhood Hits	349	Target Neighborhood Hits	341	Shared Neighborhood Hits	180
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB7_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.243593 (rank : 300)
Query Neighborhood Hits	349	Target Neighborhood Hits	290	Shared Neighborhood Hits	163
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

ITB7_MOUSE
θ value	θ > 10 (rank : 454)	NC score	0.240029 (rank : 307)
Query Neighborhood Hits	349	Target Neighborhood Hits	277	Shared Neighborhood Hits	154
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

ITB8_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.185640 (rank : 355)
Query Neighborhood Hits	349	Target Neighborhood Hits	280	Shared Neighborhood Hits	154
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

KR101_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.267020 (rank : 278)
Query Neighborhood Hits	349	Target Neighborhood Hits	261	Shared Neighborhood Hits	120
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR102_HUMAN
θ value	θ > 10 (rank : 457)	NC score	0.239342 (rank : 309)
Query Neighborhood Hits	349	Target Neighborhood Hits	264	Shared Neighborhood Hits	116
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR103_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.153759 (rank : 392)
Query Neighborhood Hits	349	Target Neighborhood Hits	212	Shared Neighborhood Hits	81
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

KR105_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.241293 (rank : 303)
Query Neighborhood Hits	349	Target Neighborhood Hits	271	Shared Neighborhood Hits	119
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR108_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.212947 (rank : 338)
Query Neighborhood Hits	349	Target Neighborhood Hits	226	Shared Neighborhood Hits	106
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR109_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.223216 (rank : 325)
Query Neighborhood Hits	349	Target Neighborhood Hits	226	Shared Neighborhood Hits	105
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR10A_HUMAN
θ value	θ > 10 (rank : 462)	NC score	0.164802 (rank : 379)
Query Neighborhood Hits	349	Target Neighborhood Hits	232	Shared Neighborhood Hits	99
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

KR10B_HUMAN
θ value	θ > 10 (rank : 463)	NC score	0.195380 (rank : 350)
Query Neighborhood Hits	349	Target Neighborhood Hits	269	Shared Neighborhood Hits	111
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KR171_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.238815 (rank : 311)
Query Neighborhood Hits	349	Target Neighborhood Hits	144	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KR410_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.103533 (rank : 464)
Query Neighborhood Hits	349	Target Neighborhood Hits	156	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

KR412_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.152916 (rank : 394)
Query Neighborhood Hits	349	Target Neighborhood Hits	178	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR413_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.090854 (rank : 490)
Query Neighborhood Hits	349	Target Neighborhood Hits	112	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

KR414_HUMAN
θ value	θ > 10 (rank : 468)	NC score	0.171538 (rank : 367)
Query Neighborhood Hits	349	Target Neighborhood Hits	199	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KR510_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.169964 (rank : 371)
Query Neighborhood Hits	349	Target Neighborhood Hits	217	Shared Neighborhood Hits	88
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KR511_HUMAN
θ value	θ > 10 (rank : 470)	NC score	0.231905 (rank : 315)
Query Neighborhood Hits	349	Target Neighborhood Hits	231	Shared Neighborhood Hits	105
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA11_HUMAN
θ value	θ > 10 (rank : 471)	NC score	0.152520 (rank : 395)
Query Neighborhood Hits	349	Target Neighborhood Hits	155	Shared Neighborhood Hits	73
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

KRA13_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.188179 (rank : 352)
Query Neighborhood Hits	349	Target Neighborhood Hits	144	Shared Neighborhood Hits	71
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

KRA15_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.151612 (rank : 396)
Query Neighborhood Hits	349	Target Neighborhood Hits	126	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KRA42_HUMAN
θ value	θ > 10 (rank : 474)	NC score	0.094178 (rank : 477)
Query Neighborhood Hits	349	Target Neighborhood Hits	149	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

KRA44_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.172699 (rank : 366)
Query Neighborhood Hits	349	Target Neighborhood Hits	162	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KRA45_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.173273 (rank : 365)
Query Neighborhood Hits	349	Target Neighborhood Hits	194	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

KRA47_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.148634 (rank : 402)
Query Neighborhood Hits	349	Target Neighborhood Hits	204	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KRA51_HUMAN
θ value	θ > 10 (rank : 478)	NC score	0.326045 (rank : 229)
Query Neighborhood Hits	349	Target Neighborhood Hits	288	Shared Neighborhood Hits	134
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA52_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.207238 (rank : 342)
Query Neighborhood Hits	349	Target Neighborhood Hits	236	Shared Neighborhood Hits	103
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KRA53_HUMAN
θ value	θ > 10 (rank : 480)	NC score	0.339259 (rank : 227)
Query Neighborhood Hits	349	Target Neighborhood Hits	331	Shared Neighborhood Hits	149
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA54_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.242597 (rank : 302)
Query Neighborhood Hits	349	Target Neighborhood Hits	270	Shared Neighborhood Hits	110
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA55_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.254168 (rank : 290)
Query Neighborhood Hits	349	Target Neighborhood Hits	257	Shared Neighborhood Hits	115
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA56_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.209750 (rank : 341)
Query Neighborhood Hits	349	Target Neighborhood Hits	207	Shared Neighborhood Hits	97
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA57_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.262294 (rank : 282)
Query Neighborhood Hits	349	Target Neighborhood Hits	269	Shared Neighborhood Hits	121
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA58_HUMAN
θ value	θ > 10 (rank : 485)	NC score	0.312102 (rank : 239)
Query Neighborhood Hits	349	Target Neighborhood Hits	324	Shared Neighborhood Hits	138
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA59_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.270261 (rank : 274)
Query Neighborhood Hits	349	Target Neighborhood Hits	310	Shared Neighborhood Hits	128
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KRA92_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.157623 (rank : 388)
Query Neighborhood Hits	349	Target Neighborhood Hits	198	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA93_HUMAN
θ value	θ > 10 (rank : 488)	NC score	0.170316 (rank : 370)
Query Neighborhood Hits	349	Target Neighborhood Hits	203	Shared Neighborhood Hits	73
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA94_HUMAN
θ value	θ > 10 (rank : 489)	NC score	0.171388 (rank : 369)
Query Neighborhood Hits	349	Target Neighborhood Hits	204	Shared Neighborhood Hits	83
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KRA98_HUMAN
θ value	θ > 10 (rank : 490)	NC score	0.177372 (rank : 362)
Query Neighborhood Hits	349	Target Neighborhood Hits	185	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA99_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.164170 (rank : 380)
Query Neighborhood Hits	349	Target Neighborhood Hits	173	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

LAMA1_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.295381 (rank : 252)
Query Neighborhood Hits	349	Target Neighborhood Hits	804	Shared Neighborhood Hits	200
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA2_MOUSE
θ value	θ > 10 (rank : 493)	NC score	0.251146 (rank : 292)
Query Neighborhood Hits	349	Target Neighborhood Hits	1198	Shared Neighborhood Hits	195
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA3_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.207129 (rank : 343)
Query Neighborhood Hits	349	Target Neighborhood Hits	760	Shared Neighborhood Hits	170
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

LAMA4_HUMAN
θ value	θ > 10 (rank : 495)	NC score	0.200480 (rank : 347)
Query Neighborhood Hits	349	Target Neighborhood Hits	708	Shared Neighborhood Hits	156
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA4_MOUSE
θ value	θ > 10 (rank : 496)	NC score	0.214330 (rank : 336)
Query Neighborhood Hits	349	Target Neighborhood Hits	584	Shared Neighborhood Hits	157
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA5_HUMAN
θ value	θ > 10 (rank : 497)	NC score	0.310161 (rank : 240)
Query Neighborhood Hits	349	Target Neighborhood Hits	976	Shared Neighborhood Hits	213
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB2_HUMAN
θ value	θ > 10 (rank : 498)	NC score	0.304287 (rank : 242)
Query Neighborhood Hits	349	Target Neighborhood Hits	692	Shared Neighborhood Hits	189
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB3_HUMAN
θ value	θ > 10 (rank : 499)	NC score	0.212427 (rank : 339)
Query Neighborhood Hits	349	Target Neighborhood Hits	461	Shared Neighborhood Hits	131
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMB3_MOUSE
θ value	θ > 10 (rank : 500)	NC score	0.239429 (rank : 308)
Query Neighborhood Hits	349	Target Neighborhood Hits	444	Shared Neighborhood Hits	153
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LAMC3_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.283467 (rank : 261)
Query Neighborhood Hits	349	Target Neighborhood Hits	588	Shared Neighborhood Hits	191
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LCE1A_HUMAN
θ value	θ > 10 (rank : 502)	NC score	0.115849 (rank : 444)
Query Neighborhood Hits	349	Target Neighborhood Hits	47	Shared Neighborhood Hits	25
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LCE1B_HUMAN
θ value	θ > 10 (rank : 503)	NC score	0.176266 (rank : 364)
Query Neighborhood Hits	349	Target Neighborhood Hits	58	Shared Neighborhood Hits	31
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
θ value	θ > 10 (rank : 504)	NC score	0.159032 (rank : 386)
Query Neighborhood Hits	349	Target Neighborhood Hits	65	Shared Neighborhood Hits	33
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1D_HUMAN
θ value	θ > 10 (rank : 505)	NC score	0.169283 (rank : 373)
Query Neighborhood Hits	349	Target Neighborhood Hits	44	Shared Neighborhood Hits	24
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE1E_HUMAN
θ value	θ > 10 (rank : 506)	NC score	0.138981 (rank : 413)
Query Neighborhood Hits	349	Target Neighborhood Hits	53	Shared Neighborhood Hits	24
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LCE1F_HUMAN
θ value	θ > 10 (rank : 507)	NC score	0.118217 (rank : 441)
Query Neighborhood Hits	349	Target Neighborhood Hits	48	Shared Neighborhood Hits	22
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LCE2A_HUMAN
θ value	θ > 10 (rank : 508)	NC score	0.055951 (rank : 613)
Query Neighborhood Hits	349	Target Neighborhood Hits	50	Shared Neighborhood Hits	20
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

LCE2B_HUMAN
θ value	θ > 10 (rank : 509)	NC score	0.068226 (rank : 540)
Query Neighborhood Hits	349	Target Neighborhood Hits	50	Shared Neighborhood Hits	21
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

LCE2C_HUMAN
θ value	θ > 10 (rank : 510)	NC score	0.081070 (rank : 509)
Query Neighborhood Hits	349	Target Neighborhood Hits	53	Shared Neighborhood Hits	20
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LCE2D_HUMAN
θ value	θ > 10 (rank : 511)	NC score	0.068233 (rank : 539)
Query Neighborhood Hits	349	Target Neighborhood Hits	50	Shared Neighborhood Hits	17
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

LCE3A_HUMAN
θ value	θ > 10 (rank : 512)	NC score	0.108244 (rank : 457)
Query Neighborhood Hits	349	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

LCE3B_HUMAN
θ value	θ > 10 (rank : 513)	NC score	0.079097 (rank : 515)
Query Neighborhood Hits	349	Target Neighborhood Hits	47	Shared Neighborhood Hits	26
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

LCE4A_HUMAN
θ value	θ > 10 (rank : 514)	NC score	0.091369 (rank : 488)
Query Neighborhood Hits	349	Target Neighborhood Hits	26	Shared Neighborhood Hits	15
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

LORI_MOUSE
θ value	θ > 10 (rank : 515)	NC score	0.102165 (rank : 466)
Query Neighborhood Hits	349	Target Neighborhood Hits	47	Shared Neighborhood Hits	17
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

LRP10_HUMAN
θ value	θ > 10 (rank : 516)	NC score	0.088227 (rank : 493)
Query Neighborhood Hits	349	Target Neighborhood Hits	197	Shared Neighborhood Hits	66
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP10_MOUSE
θ value	θ > 10 (rank : 517)	NC score	0.092202 (rank : 485)
Query Neighborhood Hits	349	Target Neighborhood Hits	169	Shared Neighborhood Hits	68
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP12_HUMAN
θ value	θ > 10 (rank : 518)	NC score	0.110387 (rank : 452)
Query Neighborhood Hits	349	Target Neighborhood Hits	205	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
θ value	θ > 10 (rank : 519)	NC score	0.110957 (rank : 450)
Query Neighborhood Hits	349	Target Neighborhood Hits	180	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP3_HUMAN
θ value	θ > 10 (rank : 520)	NC score	0.132609 (rank : 422)
Query Neighborhood Hits	349	Target Neighborhood Hits	280	Shared Neighborhood Hits	102
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

LRP6_HUMAN
θ value	θ > 10 (rank : 521)	NC score	0.240688 (rank : 305)
Query Neighborhood Hits	349	Target Neighborhood Hits	235	Shared Neighborhood Hits	147
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
θ value	θ > 10 (rank : 522)	NC score	0.238318 (rank : 312)
Query Neighborhood Hits	349	Target Neighborhood Hits	232	Shared Neighborhood Hits	146
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

MCSP_MOUSE
θ value	θ > 10 (rank : 523)	NC score	0.066958 (rank : 545)
Query Neighborhood Hits	349	Target Neighborhood Hits	108	Shared Neighborhood Hits	33
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MEGF9_HUMAN
θ value	θ > 10 (rank : 524)	NC score	0.323765 (rank : 231)
Query Neighborhood Hits	349	Target Neighborhood Hits	557	Shared Neighborhood Hits	180
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEGF9_MOUSE
θ value	θ > 10 (rank : 525)	NC score	0.296696 (rank : 249)
Query Neighborhood Hits	349	Target Neighborhood Hits	896	Shared Neighborhood Hits	170
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEP1A_MOUSE
θ value	θ > 10 (rank : 526)	NC score	0.161308 (rank : 382)
Query Neighborhood Hits	349	Target Neighborhood Hits	166	Shared Neighborhood Hits	114
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

MEP1B_HUMAN
θ value	θ > 10 (rank : 527)	NC score	0.062103 (rank : 574)
Query Neighborhood Hits	349	Target Neighborhood Hits	98	Shared Neighborhood Hits	53
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

MEP1B_MOUSE
θ value	θ > 10 (rank : 528)	NC score	0.092944 (rank : 482)
Query Neighborhood Hits	349	Target Neighborhood Hits	127	Shared Neighborhood Hits	72
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

MFGM_HUMAN
θ value	θ > 10 (rank : 529)	NC score	0.141276 (rank : 411)
Query Neighborhood Hits	349	Target Neighborhood Hits	150	Shared Neighborhood Hits	99
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

MFGM_MOUSE
θ value	θ > 10 (rank : 530)	NC score	0.274185 (rank : 270)
Query Neighborhood Hits	349	Target Neighborhood Hits	233	Shared Neighborhood Hits	136
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

MFRP_HUMAN
θ value	θ > 10 (rank : 531)	NC score	0.080513 (rank : 511)
Query Neighborhood Hits	349	Target Neighborhood Hits	165	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_MOUSE
θ value	θ > 10 (rank : 532)	NC score	0.073269 (rank : 522)
Query Neighborhood Hits	349	Target Neighborhood Hits	166	Shared Neighborhood Hits	48
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MKS3_MOUSE
θ value	θ > 10 (rank : 533)	NC score	0.079190 (rank : 513)
Query Neighborhood Hits	349	Target Neighborhood Hits	89	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

MMRN1_HUMAN
θ value	θ > 10 (rank : 534)	NC score	0.148550 (rank : 403)
Query Neighborhood Hits	349	Target Neighborhood Hits	636	Shared Neighborhood Hits	114
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

MT3_HUMAN
θ value	θ > 10 (rank : 535)	NC score	0.058959 (rank : 593)
Query Neighborhood Hits	349	Target Neighborhood Hits	82	Shared Neighborhood Hits	37
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

MT3_MOUSE
θ value	θ > 10 (rank : 536)	NC score	0.058348 (rank : 597)
Query Neighborhood Hits	349	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

MT4_HUMAN
θ value	θ > 10 (rank : 537)	NC score	0.055492 (rank : 618)
Query Neighborhood Hits	349	Target Neighborhood Hits	83	Shared Neighborhood Hits	38
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MT4_MOUSE
θ value	θ > 10 (rank : 538)	NC score	0.076417 (rank : 519)
Query Neighborhood Hits	349	Target Neighborhood Hits	102	Shared Neighborhood Hits	51
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MUC2_HUMAN
θ value	θ > 10 (rank : 539)	NC score	0.117126 (rank : 442)
Query Neighborhood Hits	349	Target Neighborhood Hits	906	Shared Neighborhood Hits	124
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MUC5B_HUMAN
θ value	θ > 10 (rank : 540)	NC score	0.187268 (rank : 353)
Query Neighborhood Hits	349	Target Neighborhood Hits	1020	Shared Neighborhood Hits	171
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MYOC_HUMAN
θ value	θ > 10 (rank : 541)	NC score	0.058923 (rank : 594)
Query Neighborhood Hits	349	Target Neighborhood Hits	489	Shared Neighborhood Hits	3
SwissProt Accessions	Q99972, O00620, Q7Z6Q9	Gene names	MYOC, GLC1A, TIGR
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

MYOC_MOUSE
θ value	θ > 10 (rank : 542)	NC score	0.070162 (rank : 527)
Query Neighborhood Hits	349	Target Neighborhood Hits	232	Shared Neighborhood Hits	3
SwissProt Accessions	O70624, O70289	Gene names	Myoc, Tigr
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

NAGPA_HUMAN
θ value	θ > 10 (rank : 543)	NC score	0.289634 (rank : 256)
Query Neighborhood Hits	349	Target Neighborhood Hits	282	Shared Neighborhood Hits	146
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NAGPA_MOUSE
θ value	θ > 10 (rank : 544)	NC score	0.282387 (rank : 262)
Query Neighborhood Hits	349	Target Neighborhood Hits	308	Shared Neighborhood Hits	160
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NET1_HUMAN
θ value	θ > 10 (rank : 545)	NC score	0.109609 (rank : 455)
Query Neighborhood Hits	349	Target Neighborhood Hits	149	Shared Neighborhood Hits	78
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

NET1_MOUSE
θ value	θ > 10 (rank : 546)	NC score	0.104695 (rank : 462)
Query Neighborhood Hits	349	Target Neighborhood Hits	151	Shared Neighborhood Hits	79
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

NET2_HUMAN
θ value	θ > 10 (rank : 547)	NC score	0.146543 (rank : 405)
Query Neighborhood Hits	349	Target Neighborhood Hits	194	Shared Neighborhood Hits	108
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

NET2_MOUSE
θ value	θ > 10 (rank : 548)	NC score	0.144236 (rank : 408)
Query Neighborhood Hits	349	Target Neighborhood Hits	193	Shared Neighborhood Hits	109
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

NET4_HUMAN
θ value	θ > 10 (rank : 549)	NC score	0.138191 (rank : 415)
Query Neighborhood Hits	349	Target Neighborhood Hits	191	Shared Neighborhood Hits	104
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

NET4_MOUSE
θ value	θ > 10 (rank : 550)	NC score	0.131037 (rank : 427)
Query Neighborhood Hits	349	Target Neighborhood Hits	180	Shared Neighborhood Hits	102
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

NETO1_HUMAN
θ value	θ > 10 (rank : 551)	NC score	0.065395 (rank : 556)
Query Neighborhood Hits	349	Target Neighborhood Hits	110	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
θ value	θ > 10 (rank : 552)	NC score	0.064863 (rank : 560)
Query Neighborhood Hits	349	Target Neighborhood Hits	109	Shared Neighborhood Hits	44
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO2_HUMAN
θ value	θ > 10 (rank : 553)	NC score	0.065342 (rank : 557)
Query Neighborhood Hits	349	Target Neighborhood Hits	109	Shared Neighborhood Hits	43
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
θ value	θ > 10 (rank : 554)	NC score	0.065850 (rank : 550)
Query Neighborhood Hits	349	Target Neighborhood Hits	113	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NFX1_HUMAN
θ value	θ > 10 (rank : 555)	NC score	0.168146 (rank : 375)
Query Neighborhood Hits	349	Target Neighborhood Hits	405	Shared Neighborhood Hits	101
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

NOE1_HUMAN
θ value	θ > 10 (rank : 556)	NC score	0.061027 (rank : 582)
Query Neighborhood Hits	349	Target Neighborhood Hits	266	Shared Neighborhood Hits	4
SwissProt Accessions	Q99784, Q969S7, Q99452	Gene names	OLFM1, NOE1, NOEL1
Domain Architecture
Description	Noelin precursor (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1).

NOE1_MOUSE
θ value	θ > 10 (rank : 557)	NC score	0.061715 (rank : 578)
Query Neighborhood Hits	349	Target Neighborhood Hits	258	Shared Neighborhood Hits	4
SwissProt Accessions	O88998, O35429, O88999, Q91XK8, Q9QWQ9, Q9QWR0	Gene names	Olfm1, Noe1, Noel, Noel1
Domain Architecture
Description	Noelin precursor (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1) (Pancortin).

NOE2_HUMAN
θ value	θ > 10 (rank : 558)	NC score	0.066072 (rank : 548)
Query Neighborhood Hits	349	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	O95897, Q6IMJ3, Q96FC2	Gene names	OLFM2, NOE2
Domain Architecture
Description	Noelin-2 precursor (Olfactomedin-2).

NOE2_MOUSE
θ value	θ > 10 (rank : 559)	NC score	0.066033 (rank : 549)
Query Neighborhood Hits	349	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BM13	Gene names	Olfm2
Domain Architecture	No domain graphic available
Description	Noelin-2 precursor (Olfactomedin-2).

NOE3_HUMAN
θ value	θ > 10 (rank : 560)	NC score	0.064020 (rank : 566)
Query Neighborhood Hits	349	Target Neighborhood Hits	109	Shared Neighborhood Hits	3
SwissProt Accessions	Q96PB7, Q8TBG1, Q96PB2, Q96PB3, Q96PB4, Q96PB5, Q96PB6	Gene names	OLFM3, NOE3
Domain Architecture
Description	Noelin-3 precursor (Olfactomedin-3) (Optimedin).

NOE3_MOUSE
θ value	θ > 10 (rank : 561)	NC score	0.063875 (rank : 567)
Query Neighborhood Hits	349	Target Neighborhood Hits	116	Shared Neighborhood Hits	3
SwissProt Accessions	P63056, Q8BKV2, Q8BLL6, Q8QZW0, Q8R4K3, Q8R4K4	Gene names	Olfm3, Noe3
Domain Architecture	No domain graphic available
Description	Noelin-3 precursor (Olfactomedin-3) (Optimedin).

NRG1_HUMAN
θ value	θ > 10 (rank : 562)	NC score	0.127059 (rank : 432)
Query Neighborhood Hits	349	Target Neighborhood Hits	285	Shared Neighborhood Hits	76
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

NRG2_HUMAN
θ value	θ > 10 (rank : 563)	NC score	0.099334 (rank : 469)
Query Neighborhood Hits	349	Target Neighborhood Hits	419	Shared Neighborhood Hits	74
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

NRG2_MOUSE
θ value	θ > 10 (rank : 564)	NC score	0.127910 (rank : 430)
Query Neighborhood Hits	349	Target Neighborhood Hits	392	Shared Neighborhood Hits	89
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

NRG4_HUMAN
θ value	θ > 10 (rank : 565)	NC score	0.133159 (rank : 421)
Query Neighborhood Hits	349	Target Neighborhood Hits	85	Shared Neighborhood Hits	52
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRG4_MOUSE
θ value	θ > 10 (rank : 566)	NC score	0.112801 (rank : 449)
Query Neighborhood Hits	349	Target Neighborhood Hits	79	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRP1_HUMAN
θ value	θ > 10 (rank : 567)	NC score	0.051463 (rank : 641)
Query Neighborhood Hits	349	Target Neighborhood Hits	119	Shared Neighborhood Hits	35
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

NRP1_MOUSE
θ value	θ > 10 (rank : 568)	NC score	0.051713 (rank : 637)
Query Neighborhood Hits	349	Target Neighborhood Hits	120	Shared Neighborhood Hits	34
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NRP2_HUMAN
θ value	θ > 10 (rank : 569)	NC score	0.056983 (rank : 605)
Query Neighborhood Hits	349	Target Neighborhood Hits	120	Shared Neighborhood Hits	35
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_MOUSE
θ value	θ > 10 (rank : 570)	NC score	0.055389 (rank : 619)
Query Neighborhood Hits	349	Target Neighborhood Hits	113	Shared Neighborhood Hits	33
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRX1A_HUMAN
θ value	θ > 10 (rank : 571)	NC score	0.155585 (rank : 389)
Query Neighborhood Hits	349	Target Neighborhood Hits	170	Shared Neighborhood Hits	99
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
θ value	θ > 10 (rank : 572)	NC score	0.155515 (rank : 390)
Query Neighborhood Hits	349	Target Neighborhood Hits	164	Shared Neighborhood Hits	98
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX2A_HUMAN
θ value	θ > 10 (rank : 573)	NC score	0.144133 (rank : 409)
Query Neighborhood Hits	349	Target Neighborhood Hits	614	Shared Neighborhood Hits	105
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX3A_HUMAN
θ value	θ > 10 (rank : 574)	NC score	0.149353 (rank : 400)
Query Neighborhood Hits	349	Target Neighborhood Hits	164	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

NTNG1_HUMAN
θ value	θ > 10 (rank : 575)	NC score	0.216905 (rank : 332)
Query Neighborhood Hits	349	Target Neighborhood Hits	247	Shared Neighborhood Hits	137
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG1_MOUSE
θ value	θ > 10 (rank : 576)	NC score	0.218707 (rank : 331)
Query Neighborhood Hits	349	Target Neighborhood Hits	246	Shared Neighborhood Hits	137
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG2_HUMAN
θ value	θ > 10 (rank : 577)	NC score	0.240581 (rank : 306)
Query Neighborhood Hits	349	Target Neighborhood Hits	276	Shared Neighborhood Hits	156
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

NTNG2_MOUSE
θ value	θ > 10 (rank : 578)	NC score	0.254160 (rank : 291)
Query Neighborhood Hits	349	Target Neighborhood Hits	276	Shared Neighborhood Hits	161
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

OLFL1_HUMAN
θ value	θ > 10 (rank : 579)	NC score	0.069061 (rank : 533)
Query Neighborhood Hits	349	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q6UWY5	Gene names	OLFML1
Domain Architecture	No domain graphic available
Description	Olfactomedin-like protein 1 precursor.

OLFL3_HUMAN
θ value	θ > 10 (rank : 580)	NC score	0.065408 (rank : 555)
Query Neighborhood Hits	349	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NRN5, Q53FR1, Q53HV9, Q5SQL6, Q69AX9, Q8NBJ2	Gene names	OLFML3
Domain Architecture
Description	Olfactomedin-like protein 3 precursor (HNOEL-iso) (hOLF44).

OLFL3_MOUSE
θ value	θ > 10 (rank : 581)	NC score	0.065314 (rank : 558)
Query Neighborhood Hits	349	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BK62, Q3V2F2, Q8C1T0, Q99K37	Gene names	Olfml3
Domain Architecture	No domain graphic available
Description	Olfactomedin-like protein 3 precursor.

PAPPA_HUMAN
θ value	θ > 10 (rank : 582)	NC score	0.062301 (rank : 571)
Query Neighborhood Hits	349	Target Neighborhood Hits	161	Shared Neighborhood Hits	58
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PAPPA_MOUSE
θ value	θ > 10 (rank : 583)	NC score	0.065500 (rank : 554)
Query Neighborhood Hits	349	Target Neighborhood Hits	153	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PCD15_HUMAN
θ value	θ > 10 (rank : 584)	NC score	0.058997 (rank : 591)
Query Neighborhood Hits	349	Target Neighborhood Hits	289	Shared Neighborhood Hits	13
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

PCD15_MOUSE
θ value	θ > 10 (rank : 585)	NC score	0.057932 (rank : 600)
Query Neighborhood Hits	349	Target Neighborhood Hits	262	Shared Neighborhood Hits	11
SwissProt Accessions	Q99PJ1	Gene names	Pcdh15
Domain Architecture
Description	Protocadherin-15 precursor.

PCD16_HUMAN
θ value	θ > 10 (rank : 586)	NC score	0.056619 (rank : 609)
Query Neighborhood Hits	349	Target Neighborhood Hits	245	Shared Neighborhood Hits	13
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

PCDLK_HUMAN
θ value	θ > 10 (rank : 587)	NC score	0.055378 (rank : 620)
Query Neighborhood Hits	349	Target Neighborhood Hits	172	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BYE9, Q9NXP8	Gene names	PCLKC
Domain Architecture	No domain graphic available
Description	Protocadherin LKC precursor (PC-LKC).

PCOC1_HUMAN
θ value	θ > 10 (rank : 588)	NC score	0.062867 (rank : 569)
Query Neighborhood Hits	349	Target Neighborhood Hits	146	Shared Neighborhood Hits	27
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC1_MOUSE
θ value	θ > 10 (rank : 589)	NC score	0.063397 (rank : 568)
Query Neighborhood Hits	349	Target Neighborhood Hits	100	Shared Neighborhood Hits	27
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC2_HUMAN
θ value	θ > 10 (rank : 590)	NC score	0.061676 (rank : 580)
Query Neighborhood Hits	349	Target Neighborhood Hits	73	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC2_MOUSE
θ value	θ > 10 (rank : 591)	NC score	0.060584 (rank : 584)
Query Neighborhood Hits	349	Target Neighborhood Hits	73	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCSK5_HUMAN
θ value	θ > 10 (rank : 592)	NC score	0.151324 (rank : 397)
Query Neighborhood Hits	349	Target Neighborhood Hits	291	Shared Neighborhood Hits	134
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

PCSK6_HUMAN
θ value	θ > 10 (rank : 593)	NC score	0.113720 (rank : 447)
Query Neighborhood Hits	349	Target Neighborhood Hits	298	Shared Neighborhood Hits	102
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

PDGFD_HUMAN
θ value	θ > 10 (rank : 594)	NC score	0.057108 (rank : 604)
Query Neighborhood Hits	349	Target Neighborhood Hits	74	Shared Neighborhood Hits	26
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

PDGFD_MOUSE
θ value	θ > 10 (rank : 595)	NC score	0.056945 (rank : 606)
Query Neighborhood Hits	349	Target Neighborhood Hits	72	Shared Neighborhood Hits	26
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

PGCA_HUMAN
θ value	θ > 10 (rank : 596)	NC score	0.143258 (rank : 410)
Query Neighborhood Hits	349	Target Neighborhood Hits	821	Shared Neighborhood Hits	142
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PGCB_HUMAN
θ value	θ > 10 (rank : 597)	NC score	0.163603 (rank : 381)
Query Neighborhood Hits	349	Target Neighborhood Hits	478	Shared Neighborhood Hits	139
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

PGCB_MOUSE
θ value	θ > 10 (rank : 598)	NC score	0.179416 (rank : 361)
Query Neighborhood Hits	349	Target Neighborhood Hits	459	Shared Neighborhood Hits	145
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

PGH1_HUMAN
θ value	θ > 10 (rank : 599)	NC score	0.092436 (rank : 484)
Query Neighborhood Hits	349	Target Neighborhood Hits	91	Shared Neighborhood Hits	61
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

PGH1_MOUSE
θ value	θ > 10 (rank : 600)	NC score	0.113305 (rank : 448)
Query Neighborhood Hits	349	Target Neighborhood Hits	100	Shared Neighborhood Hits	69
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

PGH2_HUMAN
θ value	θ > 10 (rank : 601)	NC score	0.109806 (rank : 454)
Query Neighborhood Hits	349	Target Neighborhood Hits	103	Shared Neighborhood Hits	72
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

PGH2_MOUSE
θ value	θ > 10 (rank : 602)	NC score	0.123591 (rank : 437)
Query Neighborhood Hits	349	Target Neighborhood Hits	113	Shared Neighborhood Hits	80
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

PHXR5_MOUSE
θ value	θ > 10 (rank : 603)	NC score	0.216790 (rank : 333)
Query Neighborhood Hits	349	Target Neighborhood Hits	102	Shared Neighborhood Hits	73
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

PROP_HUMAN
θ value	θ > 10 (rank : 604)	NC score	0.115131 (rank : 445)
Query Neighborhood Hits	349	Target Neighborhood Hits	126	Shared Neighborhood Hits	25
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

PROP_MOUSE
θ value	θ > 10 (rank : 605)	NC score	0.127060 (rank : 431)
Query Neighborhood Hits	349	Target Neighborhood Hits	165	Shared Neighborhood Hits	33
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

RECK_HUMAN
θ value	θ > 10 (rank : 606)	NC score	0.126904 (rank : 434)
Query Neighborhood Hits	349	Target Neighborhood Hits	189	Shared Neighborhood Hits	85
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

RECK_MOUSE
θ value	θ > 10 (rank : 607)	NC score	0.100888 (rank : 468)
Query Neighborhood Hits	349	Target Neighborhood Hits	158	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

RELN_HUMAN
θ value	θ > 10 (rank : 608)	NC score	0.126976 (rank : 433)
Query Neighborhood Hits	349	Target Neighborhood Hits	233	Shared Neighborhood Hits	123
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

RELN_MOUSE
θ value	θ > 10 (rank : 609)	NC score	0.132011 (rank : 423)
Query Neighborhood Hits	349	Target Neighborhood Hits	235	Shared Neighborhood Hits	124
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

RSPO3_HUMAN
θ value	θ > 10 (rank : 610)	NC score	0.091486 (rank : 487)
Query Neighborhood Hits	349	Target Neighborhood Hits	128	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

RSPO3_MOUSE
θ value	θ > 10 (rank : 611)	NC score	0.079181 (rank : 514)
Query Neighborhood Hits	349	Target Neighborhood Hits	120	Shared Neighborhood Hits	48
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

RSPO4_HUMAN
θ value	θ > 10 (rank : 612)	NC score	0.052183 (rank : 636)
Query Neighborhood Hits	349	Target Neighborhood Hits	110	Shared Neighborhood Hits	49
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

SEM5A_HUMAN
θ value	θ > 10 (rank : 613)	NC score	0.073239 (rank : 523)
Query Neighborhood Hits	349	Target Neighborhood Hits	177	Shared Neighborhood Hits	44
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEM5A_MOUSE
θ value	θ > 10 (rank : 614)	NC score	0.062031 (rank : 575)
Query Neighborhood Hits	349	Target Neighborhood Hits	162	Shared Neighborhood Hits	25
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEM5B_HUMAN
θ value	θ > 10 (rank : 615)	NC score	0.066806 (rank : 546)
Query Neighborhood Hits	349	Target Neighborhood Hits	178	Shared Neighborhood Hits	31
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

SEM5B_MOUSE
θ value	θ > 10 (rank : 616)	NC score	0.069036 (rank : 534)
Query Neighborhood Hits	349	Target Neighborhood Hits	190	Shared Neighborhood Hits	40
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

SEZ6L_HUMAN
θ value	θ > 10 (rank : 617)	NC score	0.057616 (rank : 602)
Query Neighborhood Hits	349	Target Neighborhood Hits	289	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

SHBG_HUMAN
θ value	θ > 10 (rank : 618)	NC score	0.068869 (rank : 536)
Query Neighborhood Hits	349	Target Neighborhood Hits	45	Shared Neighborhood Hits	20
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

SHBG_MOUSE
θ value	θ > 10 (rank : 619)	NC score	0.074118 (rank : 521)
Query Neighborhood Hits	349	Target Neighborhood Hits	50	Shared Neighborhood Hits	24
SwissProt Accessions	P97497	Gene names	Shbg
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP).

SMDF_HUMAN
θ value	θ > 10 (rank : 620)	NC score	0.125706 (rank : 435)
Query Neighborhood Hits	349	Target Neighborhood Hits	117	Shared Neighborhood Hits	55
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

SORL_MOUSE
θ value	θ > 10 (rank : 621)	NC score	0.273849 (rank : 271)
Query Neighborhood Hits	349	Target Neighborhood Hits	439	Shared Neighborhood Hits	161
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

SPON1_HUMAN
θ value	θ > 10 (rank : 622)	NC score	0.093694 (rank : 479)
Query Neighborhood Hits	349	Target Neighborhood Hits	117	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

SPON1_MOUSE
θ value	θ > 10 (rank : 623)	NC score	0.094001 (rank : 478)
Query Neighborhood Hits	349	Target Neighborhood Hits	123	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

TDGF1_HUMAN
θ value	θ > 10 (rank : 624)	NC score	0.197842 (rank : 349)
Query Neighborhood Hits	349	Target Neighborhood Hits	132	Shared Neighborhood Hits	93
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

TDGF1_MOUSE
θ value	θ > 10 (rank : 625)	NC score	0.231572 (rank : 316)
Query Neighborhood Hits	349	Target Neighborhood Hits	146	Shared Neighborhood Hits	102
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

TDGF2_HUMAN
θ value	θ > 10 (rank : 626)	NC score	0.197886 (rank : 348)
Query Neighborhood Hits	349	Target Neighborhood Hits	131	Shared Neighborhood Hits	90
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

TENA_HUMAN
θ value	θ > 10 (rank : 627)	NC score	0.389629 (rank : 209)
Query Neighborhood Hits	349	Target Neighborhood Hits	631	Shared Neighborhood Hits	219
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENA_MOUSE
θ value	θ > 10 (rank : 628)	NC score	0.383331 (rank : 212)
Query Neighborhood Hits	349	Target Neighborhood Hits	596	Shared Neighborhood Hits	215
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TENN_HUMAN
θ value	θ > 10 (rank : 629)	NC score	0.165237 (rank : 377)
Query Neighborhood Hits	349	Target Neighborhood Hits	453	Shared Neighborhood Hits	159
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENN_MOUSE
θ value	θ > 10 (rank : 630)	NC score	0.181246 (rank : 360)
Query Neighborhood Hits	349	Target Neighborhood Hits	484	Shared Neighborhood Hits	160
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENR_HUMAN
θ value	θ > 10 (rank : 631)	NC score	0.222835 (rank : 327)
Query Neighborhood Hits	349	Target Neighborhood Hits	526	Shared Neighborhood Hits	178
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TENR_MOUSE
θ value	θ > 10 (rank : 632)	NC score	0.229325 (rank : 321)
Query Neighborhood Hits	349	Target Neighborhood Hits	531	Shared Neighborhood Hits	183
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

TGFA_HUMAN
θ value	θ > 10 (rank : 633)	NC score	0.057674 (rank : 601)
Query Neighborhood Hits	349	Target Neighborhood Hits	61	Shared Neighborhood Hits	40
SwissProt Accessions	P01135, Q15577	Gene names	TGFA
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

THSD1_HUMAN
θ value	θ > 10 (rank : 634)	NC score	0.053886 (rank : 626)
Query Neighborhood Hits	349	Target Neighborhood Hits	136	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

THSD1_MOUSE
θ value	θ > 10 (rank : 635)	NC score	0.055721 (rank : 614)
Query Neighborhood Hits	349	Target Neighborhood Hits	153	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

TIE1_HUMAN
θ value	θ > 10 (rank : 636)	NC score	0.108097 (rank : 458)
Query Neighborhood Hits	349	Target Neighborhood Hits	1241	Shared Neighborhood Hits	169
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE1_MOUSE
θ value	θ > 10 (rank : 637)	NC score	0.105751 (rank : 460)
Query Neighborhood Hits	349	Target Neighborhood Hits	1266	Shared Neighborhood Hits	170
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE2_HUMAN
θ value	θ > 10 (rank : 638)	NC score	0.095119 (rank : 475)
Query Neighborhood Hits	349	Target Neighborhood Hits	1192	Shared Neighborhood Hits	178
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TMG1_HUMAN
θ value	θ > 10 (rank : 639)	NC score	0.059895 (rank : 586)
Query Neighborhood Hits	349	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	O14668	Gene names	PRRG1, PRGP1, TMG1
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 1 precursor (Proline- rich Gla protein 1) (Proline-rich gamma-carboxyglutamic acid protein 1).

TMG3_HUMAN
θ value	θ > 10 (rank : 640)	NC score	0.054065 (rank : 625)
Query Neighborhood Hits	349	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BZD7, Q8N2N6	Gene names	PRRG3, TMG3
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 3 precursor (Proline- rich Gla protein 3) (Proline-rich gamma-carboxyglutamic acid protein 3).

TMG3_MOUSE
θ value	θ > 10 (rank : 641)	NC score	0.053131 (rank : 631)
Query Neighborhood Hits	349	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PAQ9	Gene names	Prrg3, Gm368, Tmg3
Domain Architecture	No domain graphic available
Description	Transmembrane gamma-carboxyglutamic acid protein 3 precursor (Proline- rich Gla protein 3) (Proline-rich gamma-carboxyglutamic acid protein 3).

TNR11_HUMAN
θ value	θ > 10 (rank : 642)	NC score	0.069432 (rank : 530)
Query Neighborhood Hits	349	Target Neighborhood Hits	135	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR11_MOUSE
θ value	θ > 10 (rank : 643)	NC score	0.051619 (rank : 639)
Query Neighborhood Hits	349	Target Neighborhood Hits	121	Shared Neighborhood Hits	45
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR14_HUMAN
θ value	θ > 10 (rank : 644)	NC score	0.053239 (rank : 630)
Query Neighborhood Hits	349	Target Neighborhood Hits	149	Shared Neighborhood Hits	53
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TNR16_HUMAN
θ value	θ > 10 (rank : 645)	NC score	0.069206 (rank : 531)
Query Neighborhood Hits	349	Target Neighborhood Hits	183	Shared Neighborhood Hits	60
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR16_MOUSE
θ value	θ > 10 (rank : 646)	NC score	0.072619 (rank : 525)
Query Neighborhood Hits	349	Target Neighborhood Hits	178	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR25_HUMAN
θ value	θ > 10 (rank : 647)	NC score	0.114399 (rank : 446)
Query Neighborhood Hits	349	Target Neighborhood Hits	172	Shared Neighborhood Hits	59
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TNR7_HUMAN
θ value	θ > 10 (rank : 648)	NC score	0.053387 (rank : 628)
Query Neighborhood Hits	349	Target Neighborhood Hits	120	Shared Neighborhood Hits	50
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TNR8_HUMAN
θ value	θ > 10 (rank : 649)	NC score	0.052204 (rank : 635)
Query Neighborhood Hits	349	Target Neighborhood Hits	198	Shared Neighborhood Hits	53
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TNR8_MOUSE
θ value	θ > 10 (rank : 650)	NC score	0.055601 (rank : 616)
Query Neighborhood Hits	349	Target Neighborhood Hits	208	Shared Neighborhood Hits	50
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TNR9_HUMAN
θ value	θ > 10 (rank : 651)	NC score	0.084555 (rank : 501)
Query Neighborhood Hits	349	Target Neighborhood Hits	166	Shared Neighborhood Hits	55
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TPA_HUMAN
θ value	θ > 10 (rank : 652)	NC score	0.091518 (rank : 486)
Query Neighborhood Hits	349	Target Neighborhood Hits	324	Shared Neighborhood Hits	120
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TPA_MOUSE
θ value	θ > 10 (rank : 653)	NC score	0.089974 (rank : 491)
Query Neighborhood Hits	349	Target Neighborhood Hits	335	Shared Neighborhood Hits	127
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TSG6_HUMAN
θ value	θ > 10 (rank : 654)	NC score	0.083808 (rank : 503)
Query Neighborhood Hits	349	Target Neighborhood Hits	91	Shared Neighborhood Hits	33
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
θ value	θ > 10 (rank : 655)	NC score	0.083461 (rank : 504)
Query Neighborhood Hits	349	Target Neighborhood Hits	91	Shared Neighborhood Hits	32
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

UNC5A_MOUSE
θ value	θ > 10 (rank : 656)	NC score	0.067572 (rank : 544)
Query Neighborhood Hits	349	Target Neighborhood Hits	203	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5B_HUMAN
θ value	θ > 10 (rank : 657)	NC score	0.064028 (rank : 565)
Query Neighborhood Hits	349	Target Neighborhood Hits	225	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5B_MOUSE
θ value	θ > 10 (rank : 658)	NC score	0.064409 (rank : 563)
Query Neighborhood Hits	349	Target Neighborhood Hits	226	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5C_HUMAN
θ value	θ > 10 (rank : 659)	NC score	0.062015 (rank : 576)
Query Neighborhood Hits	349	Target Neighborhood Hits	226	Shared Neighborhood Hits	15
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5C_MOUSE
θ value	θ > 10 (rank : 660)	NC score	0.061700 (rank : 579)
Query Neighborhood Hits	349	Target Neighborhood Hits	225	Shared Neighborhood Hits	14
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

UNC5D_HUMAN
θ value	θ > 10 (rank : 661)	NC score	0.059819 (rank : 587)
Query Neighborhood Hits	349	Target Neighborhood Hits	267	Shared Neighborhood Hits	21
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5D_MOUSE
θ value	θ > 10 (rank : 662)	NC score	0.059924 (rank : 585)
Query Neighborhood Hits	349	Target Neighborhood Hits	268	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

USH2A_HUMAN
θ value	θ > 10 (rank : 663)	NC score	0.219652 (rank : 330)
Query Neighborhood Hits	349	Target Neighborhood Hits	600	Shared Neighborhood Hits	163
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

USH2A_MOUSE
θ value	θ > 10 (rank : 664)	NC score	0.239288 (rank : 310)
Query Neighborhood Hits	349	Target Neighborhood Hits	626	Shared Neighborhood Hits	174
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

VASN_HUMAN
θ value	θ > 10 (rank : 665)	NC score	0.105629 (rank : 461)
Query Neighborhood Hits	349	Target Neighborhood Hits	449	Shared Neighborhood Hits	98
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

VASN_MOUSE
θ value	θ > 10 (rank : 666)	NC score	0.102002 (rank : 467)
Query Neighborhood Hits	349	Target Neighborhood Hits	426	Shared Neighborhood Hits	95
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

VWF_HUMAN
θ value	θ > 10 (rank : 667)	NC score	0.182527 (rank : 358)
Query Neighborhood Hits	349	Target Neighborhood Hits	396	Shared Neighborhood Hits	142
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

VWF_MOUSE
θ value	θ > 10 (rank : 668)	NC score	0.171441 (rank : 368)
Query Neighborhood Hits	349	Target Neighborhood Hits	381	Shared Neighborhood Hits	132
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

WFDC3_HUMAN
θ value	θ > 10 (rank : 669)	NC score	0.086510 (rank : 497)
Query Neighborhood Hits	349	Target Neighborhood Hits	138	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

WIF1_HUMAN
θ value	θ > 10 (rank : 670)	NC score	0.473636 (rank : 160)
Query Neighborhood Hits	349	Target Neighborhood Hits	392	Shared Neighborhood Hits	202
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_MOUSE
θ value	θ > 10 (rank : 671)	NC score	0.467276 (rank : 166)
Query Neighborhood Hits	349	Target Neighborhood Hits	393	Shared Neighborhood Hits	196
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WISP2_HUMAN
θ value	θ > 10 (rank : 672)	NC score	0.055981 (rank : 612)
Query Neighborhood Hits	349	Target Neighborhood Hits	126	Shared Neighborhood Hits	40
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

Hits sorted by NC score

EMR1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	349	Target Neighborhood Hits	349	Shared Neighborhood Hits	349
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EMR1_HUMAN
NC score	0.989332 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	349	Target Neighborhood Hits	382	Shared Neighborhood Hits	305
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EMR2_HUMAN
NC score	0.977855 (rank : 3)	θ value	2.27638e-136 (rank : 3)
Query Neighborhood Hits	349	Target Neighborhood Hits	345	Shared Neighborhood Hits	295
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

CD97_HUMAN
NC score	0.976495 (rank : 4)	θ value	3.76964e-123 (rank : 5)
Query Neighborhood Hits	349	Target Neighborhood Hits	353	Shared Neighborhood Hits	297
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CD97_MOUSE
NC score	0.962191 (rank : 5)	θ value	2.72669e-89 (rank : 7)
Query Neighborhood Hits	349	Target Neighborhood Hits	295	Shared Neighborhood Hits	259
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

ELTD1_MOUSE
NC score	0.952938 (rank : 6)	θ value	1.71185e-83 (rank : 8)
Query Neighborhood Hits	349	Target Neighborhood Hits	288	Shared Neighborhood Hits	253
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

ELTD1_HUMAN
NC score	0.896054 (rank : 7)	θ value	8.79181e-80 (rank : 9)
Query Neighborhood Hits	349	Target Neighborhood Hits	269	Shared Neighborhood Hits	238
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

EMR3_HUMAN
NC score	0.873877 (rank : 8)	θ value	4.9119e-131 (rank : 4)
Query Neighborhood Hits	349	Target Neighborhood Hits	245	Shared Neighborhood Hits	220
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

EMR4_MOUSE
NC score	0.808956 (rank : 9)	θ value	2.89973e-107 (rank : 6)
Query Neighborhood Hits	349	Target Neighborhood Hits	191	Shared Neighborhood Hits	178
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

FBLN1_HUMAN
NC score	0.761105 (rank : 10)	θ value	2.11701e-41 (rank : 32)
Query Neighborhood Hits	349	Target Neighborhood Hits	324	Shared Neighborhood Hits	234
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN4_HUMAN
NC score	0.759569 (rank : 11)	θ value	5.97985e-28 (rank : 69)
Query Neighborhood Hits	349	Target Neighborhood Hits	278	Shared Neighborhood Hits	226
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN1_MOUSE
NC score	0.759100 (rank : 12)	θ value	3.05695e-40 (rank : 34)
Query Neighborhood Hits	349	Target Neighborhood Hits	329	Shared Neighborhood Hits	239
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN4_MOUSE
NC score	0.758321 (rank : 13)	θ value	5.97985e-28 (rank : 70)
Query Neighborhood Hits	349	Target Neighborhood Hits	270	Shared Neighborhood Hits	222
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN3_MOUSE
NC score	0.753288 (rank : 14)	θ value	2.59387e-31 (rank : 55)
Query Neighborhood Hits	349	Target Neighborhood Hits	279	Shared Neighborhood Hits	220
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN3_HUMAN
NC score	0.753250 (rank : 15)	θ value	2.86786e-30 (rank : 59)
Query Neighborhood Hits	349	Target Neighborhood Hits	293	Shared Neighborhood Hits	225
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN5_HUMAN
NC score	0.752940 (rank : 16)	θ value	3.86705e-35 (rank : 41)
Query Neighborhood Hits	349	Target Neighborhood Hits	329	Shared Neighborhood Hits	242
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
NC score	0.751853 (rank : 17)	θ value	1.46948e-34 (rank : 44)
Query Neighborhood Hits	349	Target Neighborhood Hits	317	Shared Neighborhood Hits	236
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

LTBP3_HUMAN
NC score	0.749635 (rank : 18)	θ value	1.41672e-45 (rank : 26)
Query Neighborhood Hits	349	Target Neighborhood Hits	502	Shared Neighborhood Hits	254
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

FBLN2_HUMAN
NC score	0.747316 (rank : 19)	θ value	4.41421e-39 (rank : 38)
Query Neighborhood Hits	349	Target Neighborhood Hits	392	Shared Neighborhood Hits	238
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_MOUSE
NC score	0.745056 (rank : 20)	θ value	1.98146e-39 (rank : 36)
Query Neighborhood Hits	349	Target Neighborhood Hits	505	Shared Neighborhood Hits	243
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

LTB1S_MOUSE
NC score	0.744119 (rank : 21)	θ value	7.01481e-53 (rank : 14)
Query Neighborhood Hits	349	Target Neighborhood Hits	479	Shared Neighborhood Hits	256
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP3_MOUSE
NC score	0.743892 (rank : 22)	θ value	2.50074e-42 (rank : 31)
Query Neighborhood Hits	349	Target Neighborhood Hits	475	Shared Neighborhood Hits	253
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP4_MOUSE
NC score	0.742644 (rank : 23)	θ value	1.36902e-48 (rank : 19)
Query Neighborhood Hits	349	Target Neighborhood Hits	607	Shared Neighborhood Hits	251
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

LTB1L_MOUSE
NC score	0.742372 (rank : 24)	θ value	7.01481e-53 (rank : 13)
Query Neighborhood Hits	349	Target Neighborhood Hits	514	Shared Neighborhood Hits	257
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
NC score	0.742191 (rank : 25)	θ value	2.041e-52 (rank : 16)
Query Neighborhood Hits	349	Target Neighborhood Hits	502	Shared Neighborhood Hits	257
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_HUMAN
NC score	0.742158 (rank : 26)	θ value	2.041e-52 (rank : 15)
Query Neighborhood Hits	349	Target Neighborhood Hits	553	Shared Neighborhood Hits	258
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

C1QR1_MOUSE
NC score	0.739177 (rank : 27)	θ value	5.23862e-24 (rank : 82)
Query Neighborhood Hits	349	Target Neighborhood Hits	342	Shared Neighborhood Hits	235
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

LTBP2_MOUSE
NC score	0.736507 (rank : 28)	θ value	2.58187e-47 (rank : 22)
Query Neighborhood Hits	349	Target Neighborhood Hits	617	Shared Neighborhood Hits	253
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP2_HUMAN
NC score	0.735802 (rank : 29)	θ value	5.20228e-48 (rank : 20)
Query Neighborhood Hits	349	Target Neighborhood Hits	552	Shared Neighborhood Hits	253
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

C1QR1_HUMAN
NC score	0.732105 (rank : 30)	θ value	3.39556e-23 (rank : 86)
Query Neighborhood Hits	349	Target Neighborhood Hits	493	Shared Neighborhood Hits	228
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

FBN1_HUMAN
NC score	0.726046 (rank : 31)	θ value	2.67181e-44 (rank : 27)
Query Neighborhood Hits	349	Target Neighborhood Hits	557	Shared Neighborhood Hits	264
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN3_HUMAN
NC score	0.725436 (rank : 32)	θ value	3.72821e-46 (rank : 24)
Query Neighborhood Hits	349	Target Neighborhood Hits	543	Shared Neighborhood Hits	259
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FBN1_MOUSE
NC score	0.724016 (rank : 33)	θ value	3.48949e-44 (rank : 28)
Query Neighborhood Hits	349	Target Neighborhood Hits	563	Shared Neighborhood Hits	263
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
NC score	0.723524 (rank : 34)	θ value	1.28137e-46 (rank : 23)
Query Neighborhood Hits	349	Target Neighborhood Hits	560	Shared Neighborhood Hits	263
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
NC score	0.723368 (rank : 35)	θ value	8.30557e-46 (rank : 25)
Query Neighborhood Hits	349	Target Neighborhood Hits	549	Shared Neighborhood Hits	263
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

SCUB3_HUMAN
NC score	0.720863 (rank : 36)	θ value	9.8567e-31 (rank : 57)
Query Neighborhood Hits	349	Target Neighborhood Hits	428	Shared Neighborhood Hits	244
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

NELL2_HUMAN
NC score	0.720098 (rank : 37)	θ value	4.72714e-33 (rank : 49)
Query Neighborhood Hits	349	Target Neighborhood Hits	449	Shared Neighborhood Hits	243
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

SCUB3_MOUSE
NC score	0.719088 (rank : 38)	θ value	7.54701e-31 (rank : 56)
Query Neighborhood Hits	349	Target Neighborhood Hits	442	Shared Neighborhood Hits	243
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

NELL2_MOUSE
NC score	0.719012 (rank : 39)	θ value	6.82597e-32 (rank : 53)
Query Neighborhood Hits	349	Target Neighborhood Hits	436	Shared Neighborhood Hits	244
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NELL1_HUMAN
NC score	0.711937 (rank : 40)	θ value	6.82597e-32 (rank : 52)
Query Neighborhood Hits	349	Target Neighborhood Hits	451	Shared Neighborhood Hits	240
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

SUSD1_HUMAN
NC score	0.711157 (rank : 41)	θ value	4.74913e-17 (rank : 109)
Query Neighborhood Hits	349	Target Neighborhood Hits	285	Shared Neighborhood Hits	196
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TRBM_MOUSE
NC score	0.703409 (rank : 42)	θ value	3.40345e-15 (rank : 121)
Query Neighborhood Hits	349	Target Neighborhood Hits	361	Shared Neighborhood Hits	226
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRBM_HUMAN
NC score	0.702517 (rank : 43)	θ value	2.43908e-13 (rank : 141)
Query Neighborhood Hits	349	Target Neighborhood Hits	339	Shared Neighborhood Hits	231
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

GAS6_MOUSE
NC score	0.693644 (rank : 44)	θ value	7.0802e-21 (rank : 96)
Query Neighborhood Hits	349	Target Neighborhood Hits	343	Shared Neighborhood Hits	238
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GAS6_HUMAN
NC score	0.692029 (rank : 45)	θ value	8.36355e-22 (rank : 92)
Query Neighborhood Hits	349	Target Neighborhood Hits	348	Shared Neighborhood Hits	237
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

PROS_HUMAN
NC score	0.690709 (rank : 46)	θ value	1.13037e-18 (rank : 105)
Query Neighborhood Hits	349	Target Neighborhood Hits	340	Shared Neighborhood Hits	239
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
NC score	0.690193 (rank : 47)	θ value	1.38178e-16 (rank : 110)
Query Neighborhood Hits	349	Target Neighborhood Hits	330	Shared Neighborhood Hits	236
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

UROM_HUMAN
NC score	0.676237 (rank : 48)	θ value	6.62687e-19 (rank : 104)
Query Neighborhood Hits	349	Target Neighborhood Hits	284	Shared Neighborhood Hits	214
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

CRUM1_MOUSE
NC score	0.667358 (rank : 49)	θ value	1.24688e-25 (rank : 77)
Query Neighborhood Hits	349	Target Neighborhood Hits	444	Shared Neighborhood Hits	241
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

GP133_HUMAN
NC score	0.665859 (rank : 50)	θ value	9.48078e-50 (rank : 17)
Query Neighborhood Hits	349	Target Neighborhood Hits	115	Shared Neighborhood Hits	82
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

UROM_MOUSE
NC score	0.665100 (rank : 51)	θ value	1.52774e-15 (rank : 116)
Query Neighborhood Hits	349	Target Neighborhood Hits	276	Shared Neighborhood Hits	209
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

CRUM2_HUMAN
NC score	0.664883 (rank : 52)	θ value	2.27762e-19 (rank : 101)
Query Neighborhood Hits	349	Target Neighborhood Hits	453	Shared Neighborhood Hits	240
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

CRUM1_HUMAN
NC score	0.661628 (rank : 53)	θ value	3.07116e-24 (rank : 80)
Query Neighborhood Hits	349	Target Neighborhood Hits	457	Shared Neighborhood Hits	237
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

NID2_MOUSE
NC score	0.661195 (rank : 54)	θ value	5.79196e-23 (rank : 88)
Query Neighborhood Hits	349	Target Neighborhood Hits	338	Shared Neighborhood Hits	232
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NID1_HUMAN
NC score	0.656772 (rank : 55)	θ value	1.47631e-18 (rank : 106)
Query Neighborhood Hits	349	Target Neighborhood Hits	329	Shared Neighborhood Hits	232
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_MOUSE
NC score	0.656096 (rank : 56)	θ value	5.07402e-19 (rank : 103)
Query Neighborhood Hits	349	Target Neighborhood Hits	335	Shared Neighborhood Hits	222
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_HUMAN
NC score	0.654505 (rank : 57)	θ value	1.5773e-20 (rank : 98)
Query Neighborhood Hits	349	Target Neighborhood Hits	456	Shared Neighborhood Hits	231
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

EGF_MOUSE
NC score	0.653571 (rank : 58)	θ value	4.29542e-18 (rank : 108)
Query Neighborhood Hits	349	Target Neighborhood Hits	358	Shared Neighborhood Hits	238
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

MATN2_HUMAN
NC score	0.653463 (rank : 59)	θ value	8.08199e-25 (rank : 78)
Query Neighborhood Hits	349	Target Neighborhood Hits	365	Shared Neighborhood Hits	232
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

MATN2_MOUSE
NC score	0.646936 (rank : 60)	θ value	4.01107e-24 (rank : 81)
Query Neighborhood Hits	349	Target Neighborhood Hits	356	Shared Neighborhood Hits	227
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

JAG2_HUMAN
NC score	0.645221 (rank : 61)	θ value	2.69047e-20 (rank : 100)
Query Neighborhood Hits	349	Target Neighborhood Hits	491	Shared Neighborhood Hits	243
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

EGF_HUMAN
NC score	0.645186 (rank : 62)	θ value	1.92812e-18 (rank : 107)
Query Neighborhood Hits	349	Target Neighborhood Hits	343	Shared Neighborhood Hits	231
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

JAG1_MOUSE
NC score	0.644873 (rank : 63)	θ value	1.29031e-22 (rank : 89)
Query Neighborhood Hits	349	Target Neighborhood Hits	518	Shared Neighborhood Hits	247
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG1_HUMAN
NC score	0.642765 (rank : 64)	θ value	4.9032e-22 (rank : 91)
Query Neighborhood Hits	349	Target Neighborhood Hits	514	Shared Neighborhood Hits	248
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG2_MOUSE
NC score	0.642251 (rank : 65)	θ value	2.97466e-19 (rank : 102)
Query Neighborhood Hits	349	Target Neighborhood Hits	504	Shared Neighborhood Hits	241
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

MEGF6_HUMAN
NC score	0.641559 (rank : 66)	θ value	1.2049e-28 (rank : 67)
Query Neighborhood Hits	349	Target Neighborhood Hits	671	Shared Neighborhood Hits	261
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

CREL1_HUMAN
NC score	0.638784 (rank : 67)	θ value	1.02475e-11 (rank : 153)
Query Neighborhood Hits	349	Target Neighborhood Hits	441	Shared Neighborhood Hits	206
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

GPR64_MOUSE
NC score	0.637816 (rank : 68)	θ value	1.51715e-39 (rank : 35)
Query Neighborhood Hits	349	Target Neighborhood Hits	156	Shared Neighborhood Hits	84
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

DNER_HUMAN
NC score	0.637072 (rank : 69)	θ value	1.16975e-15 (rank : 115)
Query Neighborhood Hits	349	Target Neighborhood Hits	460	Shared Neighborhood Hits	228
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DLL1_MOUSE
NC score	0.636838 (rank : 70)	θ value	5.42112e-21 (rank : 95)
Query Neighborhood Hits	349	Target Neighborhood Hits	456	Shared Neighborhood Hits	239
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

DNER_MOUSE
NC score	0.636402 (rank : 71)	θ value	1.99529e-15 (rank : 118)
Query Neighborhood Hits	349	Target Neighborhood Hits	413	Shared Neighborhood Hits	226
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

CREL1_MOUSE
NC score	0.635644 (rank : 72)	θ value	5.62301e-10 (rank : 166)
Query Neighborhood Hits	349	Target Neighborhood Hits	524	Shared Neighborhood Hits	210
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

DLL1_HUMAN
NC score	0.635337 (rank : 73)	θ value	1.86321e-21 (rank : 94)
Query Neighborhood Hits	349	Target Neighborhood Hits	455	Shared Neighborhood Hits	242
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

GPR64_HUMAN
NC score	0.634652 (rank : 74)	θ value	1.79215e-40 (rank : 33)
Query Neighborhood Hits	349	Target Neighborhood Hits	207	Shared Neighborhood Hits	81
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

GP128_HUMAN
NC score	0.634224 (rank : 75)	θ value	1.02001e-27 (rank : 71)
Query Neighborhood Hits	349	Target Neighborhood Hits	135	Shared Neighborhood Hits	94
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

GP113_HUMAN
NC score	0.630862 (rank : 76)	θ value	8.3442e-30 (rank : 60)
Query Neighborhood Hits	349	Target Neighborhood Hits	102	Shared Neighborhood Hits	89
SwissProt Accessions	Q8IZF5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3	Gene names	GPR113, PGR23
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 113 precursor (G-protein coupled receptor PGR23).

GP128_MOUSE
NC score	0.616776 (rank : 77)	θ value	6.84181e-24 (rank : 83)
Query Neighborhood Hits	349	Target Neighborhood Hits	141	Shared Neighborhood Hits	94
SwissProt Accessions	Q8BM96, Q80T42	Gene names	Gpr128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

DLL4_HUMAN
NC score	0.615905 (rank : 78)	θ value	1.99529e-15 (rank : 117)
Query Neighborhood Hits	349	Target Neighborhood Hits	435	Shared Neighborhood Hits	228
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

GPR56_HUMAN
NC score	0.614580 (rank : 79)	θ value	9.2256e-29 (rank : 65)
Query Neighborhood Hits	349	Target Neighborhood Hits	84	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y653, O95966, Q8NGB3, Q96HB4	Gene names	GPR56, TM7LN4, TM7XN1
Domain Architecture
Description	G-protein coupled receptor 56 precursor (TM7XN1 protein).

NOTC1_MOUSE
NC score	0.613926 (rank : 80)	θ value	1.52067e-31 (rank : 54)
Query Neighborhood Hits	349	Target Neighborhood Hits	916	Shared Neighborhood Hits	261
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

LPHN1_HUMAN
NC score	0.613127 (rank : 81)	θ value	5.51964e-74 (rank : 11)
Query Neighborhood Hits	349	Target Neighborhood Hits	155	Shared Neighborhood Hits	79
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

DLL4_MOUSE
NC score	0.609782 (rank : 82)	θ value	1.2105e-12 (rank : 149)
Query Neighborhood Hits	349	Target Neighborhood Hits	440	Shared Neighborhood Hits	227
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

LPHN3_HUMAN
NC score	0.608182 (rank : 83)	θ value	1.00591e-75 (rank : 10)
Query Neighborhood Hits	349	Target Neighborhood Hits	139	Shared Neighborhood Hits	82
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

EGFL7_HUMAN
NC score	0.607612 (rank : 84)	θ value	0.00390308 (rank : 223)
Query Neighborhood Hits	349	Target Neighborhood Hits	325	Shared Neighborhood Hits	213
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

GP144_HUMAN
NC score	0.607462 (rank : 85)	θ value	3.27365e-34 (rank : 45)
Query Neighborhood Hits	349	Target Neighborhood Hits	108	Shared Neighborhood Hits	84
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

TSP4_MOUSE
NC score	0.607102 (rank : 86)	θ value	2.20605e-14 (rank : 129)
Query Neighborhood Hits	349	Target Neighborhood Hits	276	Shared Neighborhood Hits	208
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_HUMAN
NC score	0.606483 (rank : 87)	θ value	2.60593e-15 (rank : 119)
Query Neighborhood Hits	349	Target Neighborhood Hits	277	Shared Neighborhood Hits	204
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

GP114_HUMAN
NC score	0.606286 (rank : 88)	θ value	1.47289e-26 (rank : 75)
Query Neighborhood Hits	349	Target Neighborhood Hits	75	Shared Neighborhood Hits	72
SwissProt Accessions	Q8IZF4, Q6ZMH7, Q6ZML4, Q86SL8, Q8IZ14	Gene names	GPR114, PGR27
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 114 precursor (G-protein coupled receptor PGR27).

GPR97_MOUSE
NC score	0.605119 (rank : 89)	θ value	1.80048e-24 (rank : 79)
Query Neighborhood Hits	349	Target Neighborhood Hits	89	Shared Neighborhood Hits	79
SwissProt Accessions	Q8R0T6	Gene names	Gpr97
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor.

DLL3_MOUSE
NC score	0.605032 (rank : 90)	θ value	3.29651e-10 (rank : 162)
Query Neighborhood Hits	349	Target Neighborhood Hits	399	Shared Neighborhood Hits	218
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

DLK_MOUSE
NC score	0.604717 (rank : 91)	θ value	8.97725e-08 (rank : 185)
Query Neighborhood Hits	349	Target Neighborhood Hits	374	Shared Neighborhood Hits	216
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

LPHN2_HUMAN
NC score	0.604543 (rank : 92)	θ value	5.1662e-72 (rank : 12)
Query Neighborhood Hits	349	Target Neighborhood Hits	136	Shared Neighborhood Hits	82
SwissProt Accessions	O95490, O94882, Q5VX76, Q9UKY5, Q9UKY6	Gene names	LPHN2, KIAA0786, LEC1, LPHH1
Domain Architecture
Description	Latrophilin-2 precursor (Calcium-independent alpha-latrotoxin receptor 2) (Latrophilin homolog 1) (Lectomedin-1).

GPR56_MOUSE
NC score	0.603698 (rank : 93)	θ value	1.28732e-30 (rank : 58)
Query Neighborhood Hits	349	Target Neighborhood Hits	89	Shared Neighborhood Hits	78
SwissProt Accessions	Q8K209, Q3UR17, Q9QZT2	Gene names	Gpr56, Cyt28
Domain Architecture
Description	G-protein coupled receptor 56 precursor (Serpentine receptor cyt28).

DLK_HUMAN
NC score	0.602956 (rank : 94)	θ value	1.80886e-08 (rank : 181)
Query Neighborhood Hits	349	Target Neighborhood Hits	401	Shared Neighborhood Hits	216
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

CUBN_MOUSE
NC score	0.602484 (rank : 95)	θ value	2.51237e-26 (rank : 76)
Query Neighborhood Hits	349	Target Neighborhood Hits	477	Shared Neighborhood Hits	251
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

NOTC2_MOUSE
NC score	0.601759 (rank : 96)	θ value	1.33217e-27 (rank : 72)
Query Neighborhood Hits	349	Target Neighborhood Hits	1069	Shared Neighborhood Hits	259
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

EGFL9_MOUSE
NC score	0.601483 (rank : 97)	θ value	1.53129e-07 (rank : 187)
Query Neighborhood Hits	349	Target Neighborhood Hits	379	Shared Neighborhood Hits	220
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

NOTC2_HUMAN
NC score	0.600493 (rank : 98)	θ value	9.2256e-29 (rank : 66)
Query Neighborhood Hits	349	Target Neighborhood Hits	1113	Shared Neighborhood Hits	262
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC3_HUMAN
NC score	0.599725 (rank : 99)	θ value	2.42779e-29 (rank : 63)
Query Neighborhood Hits	349	Target Neighborhood Hits	1062	Shared Neighborhood Hits	258
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

EGFL9_HUMAN
NC score	0.598613 (rank : 100)	θ value	1.99992e-07 (rank : 189)
Query Neighborhood Hits	349	Target Neighborhood Hits	365	Shared Neighborhood Hits	219
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

NOTC3_MOUSE
NC score	0.598332 (rank : 101)	θ value	2.42779e-29 (rank : 64)
Query Neighborhood Hits	349	Target Neighborhood Hits	975	Shared Neighborhood Hits	263
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC1_HUMAN
NC score	0.596883 (rank : 102)	θ value	1.57365e-28 (rank : 68)
Query Neighborhood Hits	349	Target Neighborhood Hits	906	Shared Neighborhood Hits	262
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

COMP_MOUSE
NC score	0.594581 (rank : 103)	θ value	9.26847e-13 (rank : 148)
Query Neighborhood Hits	349	Target Neighborhood Hits	290	Shared Neighborhood Hits	190
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

DLL3_HUMAN
NC score	0.594368 (rank : 104)	θ value	3.29651e-10 (rank : 161)
Query Neighborhood Hits	349	Target Neighborhood Hits	419	Shared Neighborhood Hits	214
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

EGFL7_MOUSE
NC score	0.593079 (rank : 105)	θ value	0.00869519 (rank : 231)
Query Neighborhood Hits	349	Target Neighborhood Hits	287	Shared Neighborhood Hits	197
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

CUBN_HUMAN
NC score	0.591294 (rank : 106)	θ value	1.86321e-21 (rank : 93)
Query Neighborhood Hits	349	Target Neighborhood Hits	482	Shared Neighborhood Hits	247
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

NOTC4_HUMAN
NC score	0.588726 (rank : 107)	θ value	1.12775e-26 (rank : 74)
Query Neighborhood Hits	349	Target Neighborhood Hits	905	Shared Neighborhood Hits	263
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC4_MOUSE
NC score	0.587419 (rank : 108)	θ value	8.3442e-30 (rank : 61)
Query Neighborhood Hits	349	Target Neighborhood Hits	872	Shared Neighborhood Hits	257
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

COMP_HUMAN
NC score	0.582883 (rank : 109)	θ value	2.28291e-11 (rank : 156)
Query Neighborhood Hits	349	Target Neighborhood Hits	258	Shared Neighborhood Hits	185
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

GPR97_HUMAN
NC score	0.582430 (rank : 110)	θ value	2.69047e-20 (rank : 99)
Query Neighborhood Hits	349	Target Neighborhood Hits	86	Shared Neighborhood Hits	75
SwissProt Accessions	Q86Y34, Q6ZMF4, Q86SL9, Q8IZF1	Gene names	GPR97, PGR26
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor (G-protein coupled receptor PGR26).

MATN4_HUMAN
NC score	0.580612 (rank : 111)	θ value	3.29651e-10 (rank : 163)
Query Neighborhood Hits	349	Target Neighborhood Hits	287	Shared Neighborhood Hits	206
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

EGFL8_MOUSE
NC score	0.578860 (rank : 112)	θ value	0.00228821 (rank : 218)
Query Neighborhood Hits	349	Target Neighborhood Hits	266	Shared Neighborhood Hits	198
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

GP112_HUMAN
NC score	0.577603 (rank : 113)	θ value	5.584e-34 (rank : 46)
Query Neighborhood Hits	349	Target Neighborhood Hits	441	Shared Neighborhood Hits	89
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

MATN3_MOUSE
NC score	0.574753 (rank : 114)	θ value	1.25267e-09 (rank : 171)
Query Neighborhood Hits	349	Target Neighborhood Hits	261	Shared Neighborhood Hits	195
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

STAB1_HUMAN
NC score	0.574446 (rank : 115)	θ value	2.88119e-14 (rank : 130)
Query Neighborhood Hits	349	Target Neighborhood Hits	546	Shared Neighborhood Hits	245
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB2_HUMAN
NC score	0.574088 (rank : 116)	θ value	1.86753e-13 (rank : 139)
Query Neighborhood Hits	349	Target Neighborhood Hits	534	Shared Neighborhood Hits	234
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

EGFL8_HUMAN
NC score	0.573883 (rank : 117)	θ value	0.0252991 (rank : 236)
Query Neighborhood Hits	349	Target Neighborhood Hits	270	Shared Neighborhood Hits	199
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

MATN3_HUMAN
NC score	0.572401 (rank : 118)	θ value	8.11959e-09 (rank : 178)
Query Neighborhood Hits	349	Target Neighborhood Hits	268	Shared Neighborhood Hits	195
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

TSP3_MOUSE
NC score	0.571475 (rank : 119)	θ value	1.68911e-14 (rank : 128)
Query Neighborhood Hits	349	Target Neighborhood Hits	247	Shared Neighborhood Hits	181
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_HUMAN
NC score	0.571460 (rank : 120)	θ value	3.76295e-14 (rank : 132)
Query Neighborhood Hits	349	Target Neighborhood Hits	250	Shared Neighborhood Hits	183
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

STAB2_MOUSE
NC score	0.570938 (rank : 121)	θ value	7.09661e-13 (rank : 146)
Query Neighborhood Hits	349	Target Neighborhood Hits	528	Shared Neighborhood Hits	233
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

GP126_HUMAN
NC score	0.570467 (rank : 122)	θ value	1.4233e-29 (rank : 62)
Query Neighborhood Hits	349	Target Neighborhood Hits	187	Shared Neighborhood Hits	101
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

GP110_HUMAN
NC score	0.569855 (rank : 123)	θ value	3.39556e-23 (rank : 87)
Query Neighborhood Hits	349	Target Neighborhood Hits	87	Shared Neighborhood Hits	68
SwissProt Accessions	Q5T601, Q5KU15, Q5T5Z9, Q86SM1, Q8IXE3, Q8IZF8, Q96DQ1	Gene names	GPR110, PGR19
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 110 precursor (G-protein coupled receptor PGR19) (G-protein coupled receptor KPG_012).

GP116_HUMAN
NC score	0.567448 (rank : 124)	θ value	1.73987e-27 (rank : 73)
Query Neighborhood Hits	349	Target Neighborhood Hits	167	Shared Neighborhood Hits	70
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

GP110_MOUSE
NC score	0.566968 (rank : 125)	θ value	1.16704e-23 (rank : 84)
Query Neighborhood Hits	349	Target Neighborhood Hits	92	Shared Neighborhood Hits	71
SwissProt Accessions	Q8VEC3, Q8BMV8	Gene names	Gpr110
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 110 precursor.

STAB1_MOUSE
NC score	0.565509 (rank : 126)	θ value	1.80466e-16 (rank : 111)
Query Neighborhood Hits	349	Target Neighborhood Hits	566	Shared Neighborhood Hits	240
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

CD248_MOUSE
NC score	0.560279 (rank : 127)	θ value	0.000270298 (rank : 205)
Query Neighborhood Hits	349	Target Neighborhood Hits	578	Shared Neighborhood Hits	203
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

GP115_MOUSE
NC score	0.550986 (rank : 128)	θ value	1.6852e-22 (rank : 90)
Query Neighborhood Hits	349	Target Neighborhood Hits	69	Shared Neighborhood Hits	63
SwissProt Accessions	Q9D2L6	Gene names	Gpr115
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 precursor.

MATN4_MOUSE
NC score	0.547110 (rank : 129)	θ value	1.38499e-08 (rank : 180)
Query Neighborhood Hits	349	Target Neighborhood Hits	277	Shared Neighborhood Hits	205
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

GP115_HUMAN
NC score	0.546700 (rank : 130)	θ value	1.99067e-23 (rank : 85)
Query Neighborhood Hits	349	Target Neighborhood Hits	87	Shared Neighborhood Hits	63
SwissProt Accessions	Q8IZF3, Q5T5B5, Q5T5B6, Q86SN9, Q8IXE6	Gene names	GPR115, PGR18
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 (G-protein coupled receptor PGR18).

CD248_HUMAN
NC score	0.542021 (rank : 131)	θ value	7.1131e-05 (rank : 202)
Query Neighborhood Hits	349	Target Neighborhood Hits	679	Shared Neighborhood Hits	206
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

GP111_HUMAN
NC score	0.517801 (rank : 132)	θ value	1.2077e-20 (rank : 97)
Query Neighborhood Hits	349	Target Neighborhood Hits	77	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IZF7, Q86SL6, Q8NGU5, Q8TDT5	Gene names	GPR111, PGR20
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 111 (G-protein coupled receptor PGR20).

BAI1_HUMAN
NC score	0.515006 (rank : 133)	θ value	7.29293e-34 (rank : 47)
Query Neighborhood Hits	349	Target Neighborhood Hits	375	Shared Neighborhood Hits	99
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

LRP1_HUMAN
NC score	0.514952 (rank : 134)	θ value	6.64225e-11 (rank : 157)
Query Neighborhood Hits	349	Target Neighborhood Hits	617	Shared Neighborhood Hits	254
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP1B_MOUSE
NC score	0.514212 (rank : 135)	θ value	3.64472e-09 (rank : 175)
Query Neighborhood Hits	349	Target Neighborhood Hits	606	Shared Neighborhood Hits	261
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

BAI1_MOUSE
NC score	0.513304 (rank : 136)	θ value	4.72714e-33 (rank : 48)
Query Neighborhood Hits	349	Target Neighborhood Hits	340	Shared Neighborhood Hits	99
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

LRP1B_HUMAN
NC score	0.513193 (rank : 137)	θ value	4.76016e-09 (rank : 176)
Query Neighborhood Hits	349	Target Neighborhood Hits	602	Shared Neighborhood Hits	260
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

BAI2_MOUSE
NC score	0.511709 (rank : 138)	θ value	6.82597e-32 (rank : 51)
Query Neighborhood Hits	349	Target Neighborhood Hits	323	Shared Neighborhood Hits	106
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI3_MOUSE
NC score	0.510405 (rank : 139)	θ value	5.0505e-35 (rank : 43)
Query Neighborhood Hits	349	Target Neighborhood Hits	250	Shared Neighborhood Hits	105
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_HUMAN
NC score	0.510384 (rank : 140)	θ value	5.0505e-35 (rank : 42)
Query Neighborhood Hits	349	Target Neighborhood Hits	246	Shared Neighborhood Hits	104
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI2_HUMAN
NC score	0.509618 (rank : 141)	θ value	5.22648e-32 (rank : 50)
Query Neighborhood Hits	349	Target Neighborhood Hits	332	Shared Neighborhood Hits	103
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

LDLR_HUMAN
NC score	0.508868 (rank : 142)	θ value	1.06045e-08 (rank : 179)
Query Neighborhood Hits	349	Target Neighborhood Hits	375	Shared Neighborhood Hits	227
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

CELR1_HUMAN
NC score	0.507159 (rank : 143)	θ value	2.75849e-49 (rank : 18)
Query Neighborhood Hits	349	Target Neighborhood Hits	613	Shared Neighborhood Hits	272
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CELR1_MOUSE
NC score	0.506602 (rank : 144)	θ value	2.58187e-47 (rank : 21)
Query Neighborhood Hits	349	Target Neighborhood Hits	617	Shared Neighborhood Hits	275
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

CELR2_HUMAN
NC score	0.503433 (rank : 145)	θ value	3.85808e-43 (rank : 29)
Query Neighborhood Hits	349	Target Neighborhood Hits	657	Shared Neighborhood Hits	295
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

VLDLR_MOUSE
NC score	0.498966 (rank : 146)	θ value	7.59969e-07 (rank : 194)
Query Neighborhood Hits	349	Target Neighborhood Hits	360	Shared Neighborhood Hits	227
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

LRP2_HUMAN
NC score	0.496795 (rank : 147)	θ value	3.76295e-14 (rank : 131)
Query Neighborhood Hits	349	Target Neighborhood Hits	573	Shared Neighborhood Hits	255
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

VLDLR_HUMAN
NC score	0.495526 (rank : 148)	θ value	7.59969e-07 (rank : 193)
Query Neighborhood Hits	349	Target Neighborhood Hits	383	Shared Neighborhood Hits	228
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

LRP8_MOUSE
NC score	0.492348 (rank : 149)	θ value	1.63604e-09 (rank : 172)
Query Neighborhood Hits	349	Target Neighborhood Hits	385	Shared Neighborhood Hits	221
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LDLR_MOUSE
NC score	0.487567 (rank : 150)	θ value	7.34386e-10 (rank : 168)
Query Neighborhood Hits	349	Target Neighborhood Hits	382	Shared Neighborhood Hits	229
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP8_HUMAN
NC score	0.487000 (rank : 151)	θ value	1.53129e-07 (rank : 188)
Query Neighborhood Hits	349	Target Neighborhood Hits	346	Shared Neighborhood Hits	213
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

CELR3_HUMAN
NC score	0.486592 (rank : 152)	θ value	1.6774e-38 (rank : 39)
Query Neighborhood Hits	349	Target Neighborhood Hits	680	Shared Neighborhood Hits	281
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CELR2_MOUSE
NC score	0.486344 (rank : 153)	θ value	1.46607e-42 (rank : 30)
Query Neighborhood Hits	349	Target Neighborhood Hits	584	Shared Neighborhood Hits	265
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

MEGF8_MOUSE
NC score	0.485802 (rank : 154)	θ value	0.00035302 (rank : 206)
Query Neighborhood Hits	349	Target Neighborhood Hits	520	Shared Neighborhood Hits	224
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_HUMAN
NC score	0.485059 (rank : 155)	θ value	0.000461057 (rank : 208)
Query Neighborhood Hits	349	Target Neighborhood Hits	528	Shared Neighborhood Hits	228
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

CELR3_MOUSE
NC score	0.483527 (rank : 156)	θ value	3.37985e-39 (rank : 37)
Query Neighborhood Hits	349	Target Neighborhood Hits	687	Shared Neighborhood Hits	281
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

HMCN1_HUMAN
NC score	0.482265 (rank : 157)	θ value	3.16345e-37 (rank : 40)
Query Neighborhood Hits	349	Target Neighborhood Hits	983	Shared Neighborhood Hits	247
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

CRFR2_MOUSE
NC score	0.477272 (rank : 158)	θ value	3.40345e-15 (rank : 120)
Query Neighborhood Hits	349	Target Neighborhood Hits	76	Shared Neighborhood Hits	73
SwissProt Accessions	Q60748, Q60783, Q60808	Gene names	Crhr2, Crf2r
Domain Architecture
Description	Corticotropin-releasing factor receptor 2 precursor (CRF-R 2) (CRF2) (Corticotropin-releasing hormone receptor 2) (CRH-R 2) (CRF-RB) (CRH- R2).

CRFR1_MOUSE
NC score	0.476098 (rank : 159)	θ value	4.44505e-15 (rank : 122)
Query Neighborhood Hits	349	Target Neighborhood Hits	83	Shared Neighborhood Hits	73
SwissProt Accessions	P35347	Gene names	Crhr1, Crhr
Domain Architecture
Description	Corticotropin-releasing factor receptor 1 precursor (CRF-R) (CRF1) (Corticotropin-releasing hormone receptor 1) (CRH-R 1).

WIF1_HUMAN
NC score	0.473636 (rank : 160)	θ value	θ > 10 (rank : 670)
Query Neighborhood Hits	349	Target Neighborhood Hits	392	Shared Neighborhood Hits	202
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

SREC_HUMAN
NC score	0.472101 (rank : 161)	θ value	0.21417 (rank : 258)
Query Neighborhood Hits	349	Target Neighborhood Hits	645	Shared Neighborhood Hits	219
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

SLIT1_MOUSE
NC score	0.471175 (rank : 162)	θ value	1.09485e-13 (rank : 136)
Query Neighborhood Hits	349	Target Neighborhood Hits	715	Shared Neighborhood Hits	231
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

TSP1_MOUSE
NC score	0.470243 (rank : 163)	θ value	2.61198e-07 (rank : 191)
Query Neighborhood Hits	349	Target Neighborhood Hits	396	Shared Neighborhood Hits	195
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

CRFR2_HUMAN
NC score	0.469380 (rank : 164)	θ value	4.44505e-15 (rank : 123)
Query Neighborhood Hits	349	Target Neighborhood Hits	76	Shared Neighborhood Hits	73
SwissProt Accessions	Q13324, O43461, Q99431	Gene names	CRHR2, CRF2R, CRH2R
Domain Architecture
Description	Corticotropin-releasing factor receptor 2 precursor (CRF-R 2) (CRF2) (Corticotropin-releasing hormone receptor 2) (CRH-R 2).

SLIT1_HUMAN
NC score	0.468814 (rank : 165)	θ value	5.43371e-13 (rank : 144)
Query Neighborhood Hits	349	Target Neighborhood Hits	700	Shared Neighborhood Hits	230
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

WIF1_MOUSE
NC score	0.467276 (rank : 166)	θ value	θ > 10 (rank : 671)
Query Neighborhood Hits	349	Target Neighborhood Hits	393	Shared Neighborhood Hits	196
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

TSP1_HUMAN
NC score	0.467247 (rank : 167)	θ value	1.99992e-07 (rank : 190)
Query Neighborhood Hits	349	Target Neighborhood Hits	389	Shared Neighborhood Hits	191
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

CRFR1_HUMAN
NC score	0.466380 (rank : 168)	θ value	1.133e-10 (rank : 158)
Query Neighborhood Hits	349	Target Neighborhood Hits	82	Shared Neighborhood Hits	72
SwissProt Accessions	P34998, Q13008, Q9UK64	Gene names	CRHR1, CRFR, CRFR1, CRHR
Domain Architecture
Description	Corticotropin-releasing factor receptor 1 precursor (CRF-R) (CRF1) (Corticotropin-releasing hormone receptor 1) (CRH-R 1).

LRP4_MOUSE
NC score	0.465119 (rank : 169)	θ value	3.77169e-06 (rank : 197)
Query Neighborhood Hits	349	Target Neighborhood Hits	351	Shared Neighborhood Hits	226
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

SLIT2_HUMAN
NC score	0.462587 (rank : 170)	θ value	1.68911e-14 (rank : 127)
Query Neighborhood Hits	349	Target Neighborhood Hits	708	Shared Neighborhood Hits	235
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

LRP4_HUMAN
NC score	0.460862 (rank : 171)	θ value	3.77169e-06 (rank : 196)
Query Neighborhood Hits	349	Target Neighborhood Hits	355	Shared Neighborhood Hits	226
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

SLIT2_MOUSE
NC score	0.459682 (rank : 172)	θ value	1.2105e-12 (rank : 150)
Query Neighborhood Hits	349	Target Neighborhood Hits	684	Shared Neighborhood Hits	228
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SREC2_MOUSE
NC score	0.459104 (rank : 173)	θ value	0.0431538 (rank : 242)
Query Neighborhood Hits	349	Target Neighborhood Hits	605	Shared Neighborhood Hits	221
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

EDIL3_HUMAN
NC score	0.458115 (rank : 174)	θ value	3.19293e-05 (rank : 199)
Query Neighborhood Hits	349	Target Neighborhood Hits	292	Shared Neighborhood Hits	192
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

PROZ_MOUSE
NC score	0.457022 (rank : 175)	θ value	0.00102713 (rank : 211)
Query Neighborhood Hits	349	Target Neighborhood Hits	410	Shared Neighborhood Hits	212
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_HUMAN
NC score	0.453252 (rank : 176)	θ value	0.00509761 (rank : 226)
Query Neighborhood Hits	349	Target Neighborhood Hits	422	Shared Neighborhood Hits	224
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

EDIL3_MOUSE
NC score	0.450321 (rank : 177)	θ value	0.000158464 (rank : 203)
Query Neighborhood Hits	349	Target Neighborhood Hits	317	Shared Neighborhood Hits	199
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

SREC2_HUMAN
NC score	0.450046 (rank : 178)	θ value	0.00665767 (rank : 229)
Query Neighborhood Hits	349	Target Neighborhood Hits	645	Shared Neighborhood Hits	216
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SLIT3_HUMAN
NC score	0.448778 (rank : 179)	θ value	1.09485e-13 (rank : 137)
Query Neighborhood Hits	349	Target Neighborhood Hits	682	Shared Neighborhood Hits	220
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

SLIT3_MOUSE
NC score	0.447921 (rank : 180)	θ value	2.43908e-13 (rank : 140)
Query Neighborhood Hits	349	Target Neighborhood Hits	700	Shared Neighborhood Hits	222
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

TSP2_HUMAN
NC score	0.443700 (rank : 181)	θ value	8.40245e-06 (rank : 198)
Query Neighborhood Hits	349	Target Neighborhood Hits	359	Shared Neighborhood Hits	175
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

VIPR1_MOUSE
NC score	0.442869 (rank : 182)	θ value	6.41864e-14 (rank : 134)
Query Neighborhood Hits	349	Target Neighborhood Hits	89	Shared Neighborhood Hits	76
SwissProt Accessions	P97751, Q9JI40, Q9R1T8	Gene names	Vipr1
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 1 precursor (VIP-R-1) (VPAC1) (Pituitary adenylate cyclase-activating polypeptide type II receptor) (PACAP type II receptor) (PACAP-R-2).

PACR_MOUSE
NC score	0.436577 (rank : 183)	θ value	9.59137e-10 (rank : 170)
Query Neighborhood Hits	349	Target Neighborhood Hits	83	Shared Neighborhood Hits	74
SwissProt Accessions	P70205	Gene names	Adcyap1r1
Domain Architecture
Description	Pituitary adenylate cyclase-activating polypeptide type I receptor precursor (PACAP type I receptor) (PACAP-R-1).

CALCR_HUMAN
NC score	0.435992 (rank : 184)	θ value	1.9326e-10 (rank : 159)
Query Neighborhood Hits	349	Target Neighborhood Hits	67	Shared Neighborhood Hits	64
SwissProt Accessions	P30988, O14585, Q13941, Q6DJU8, Q6T712	Gene names	CALCR
Domain Architecture
Description	Calcitonin receptor precursor (CT-R).

PACR_HUMAN
NC score	0.435737 (rank : 185)	θ value	7.09661e-13 (rank : 145)
Query Neighborhood Hits	349	Target Neighborhood Hits	86	Shared Neighborhood Hits	76
SwissProt Accessions	P41586	Gene names	ADCYAP1R1
Domain Architecture
Description	Pituitary adenylate cyclase-activating polypeptide type I receptor precursor (PACAP type I receptor) (PACAP-R-1).

VIPR2_MOUSE
NC score	0.434406 (rank : 186)	θ value	3.29651e-10 (rank : 164)
Query Neighborhood Hits	349	Target Neighborhood Hits	98	Shared Neighborhood Hits	72
SwissProt Accessions	P41588, P97750	Gene names	Vipr2
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3).

TSP2_MOUSE
NC score	0.432835 (rank : 187)	θ value	4.0297e-08 (rank : 183)
Query Neighborhood Hits	349	Target Neighborhood Hits	352	Shared Neighborhood Hits	174
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

VIPR2_HUMAN
NC score	0.428508 (rank : 188)	θ value	4.16044e-13 (rank : 143)
Query Neighborhood Hits	349	Target Neighborhood Hits	97	Shared Neighborhood Hits	74
SwissProt Accessions	P41587, Q13053, Q15870	Gene names	VIPR2, VIP2R
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) (Helodermin-preferring VIP receptor).

PTHR1_HUMAN
NC score	0.428396 (rank : 189)	θ value	6.00763e-12 (rank : 152)
Query Neighborhood Hits	349	Target Neighborhood Hits	85	Shared Neighborhood Hits	73
SwissProt Accessions	Q03431	Gene names	PTHR1, PTHR
Domain Architecture
Description	Parathyroid hormone/parathyroid hormone-related peptide receptor precursor (PTH/PTHr receptor) (PTH/PTHrP type I receptor).

ZAN_MOUSE
NC score	0.428392 (rank : 190)	θ value	6.87365e-08 (rank : 184)
Query Neighborhood Hits	349	Target Neighborhood Hits	808	Shared Neighborhood Hits	227
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

CALCR_MOUSE
NC score	0.425972 (rank : 191)	θ value	4.30538e-10 (rank : 165)
Query Neighborhood Hits	349	Target Neighborhood Hits	76	Shared Neighborhood Hits	68
SwissProt Accessions	Q60755	Gene names	Calcr
Domain Architecture
Description	Calcitonin receptor precursor (CT-R).

VIPR1_HUMAN
NC score	0.424059 (rank : 192)	θ value	1.29331e-14 (rank : 126)
Query Neighborhood Hits	349	Target Neighborhood Hits	84	Shared Neighborhood Hits	70
SwissProt Accessions	P32241, Q15871	Gene names	VIPR1
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 1 precursor (VIP-R-1) (Pituitary adenylate cyclase-activating polypeptide type II receptor) (PACAP type II receptor) (PACAP-R-2).

GLP1R_MOUSE
NC score	0.423444 (rank : 193)	θ value	1.74796e-11 (rank : 155)
Query Neighborhood Hits	349	Target Neighborhood Hits	80	Shared Neighborhood Hits	69
SwissProt Accessions	O35659	Gene names	Glp1r
Domain Architecture
Description	Glucagon-like peptide 1 receptor precursor (GLP-1 receptor) (GLP-1-R) (GLP-1R).

CALRL_HUMAN
NC score	0.422118 (rank : 194)	θ value	1.58096e-12 (rank : 151)
Query Neighborhood Hits	349	Target Neighborhood Hits	71	Shared Neighborhood Hits	66
SwissProt Accessions	Q16602	Gene names	CALCRL, CGRPR
Domain Architecture
Description	Calcitonin gene-related peptide type 1 receptor precursor (CGRP type 1 receptor) (Calcitonin receptor-like receptor).

CALRL_MOUSE
NC score	0.421298 (rank : 195)	θ value	9.26847e-13 (rank : 147)
Query Neighborhood Hits	349	Target Neighborhood Hits	71	Shared Neighborhood Hits	66
SwissProt Accessions	Q9R1W5, Q9QXH8, Q9WUP2	Gene names	Calcrl, Crlr
Domain Architecture
Description	Calcitonin gene-related peptide type 1 receptor precursor (CGRP type 1 receptor) (Calcitonin receptor-like receptor).

SCTR_HUMAN
NC score	0.420815 (rank : 196)	θ value	2.35696e-16 (rank : 112)
Query Neighborhood Hits	349	Target Neighborhood Hits	70	Shared Neighborhood Hits	67
SwissProt Accessions	P47872, Q12961, Q13213	Gene names	SCTR
Domain Architecture
Description	Secretin receptor precursor (SCT-R).

GPR98_HUMAN
NC score	0.417958 (rank : 197)	θ value	7.58209e-15 (rank : 124)
Query Neighborhood Hits	349	Target Neighborhood Hits	202	Shared Neighborhood Hits	79
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

GLP1R_HUMAN
NC score	0.415221 (rank : 198)	θ value	1.9326e-10 (rank : 160)
Query Neighborhood Hits	349	Target Neighborhood Hits	84	Shared Neighborhood Hits	67
SwissProt Accessions	P43220, Q99669	Gene names	GLP1R
Domain Architecture
Description	Glucagon-like peptide 1 receptor precursor (GLP-1 receptor) (GLP-1-R) (GLP-1R).

PTHR1_MOUSE
NC score	0.411092 (rank : 199)	θ value	1.63604e-09 (rank : 173)
Query Neighborhood Hits	349	Target Neighborhood Hits	90	Shared Neighborhood Hits	72
SwissProt Accessions	P41593, Q62119	Gene names	Pthr1, Pthr
Domain Architecture
Description	Parathyroid hormone/parathyroid hormone-related peptide receptor precursor (PTH/PTHr receptor) (PTH/PTHrP type I receptor).

GHRHR_HUMAN
NC score	0.408451 (rank : 200)	θ value	3.64472e-09 (rank : 174)
Query Neighborhood Hits	349	Target Neighborhood Hits	78	Shared Neighborhood Hits	72
SwissProt Accessions	Q02643, Q99863	Gene names	GHRHR
Domain Architecture
Description	Growth hormone-releasing hormone receptor precursor (GHRH receptor) (GRF receptor) (GRFR).

GPR98_MOUSE
NC score	0.407149 (rank : 201)	θ value	8.95645e-16 (rank : 114)
Query Neighborhood Hits	349	Target Neighborhood Hits	206	Shared Neighborhood Hits	78
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

SCTR_MOUSE
NC score	0.406041 (rank : 202)	θ value	6.41864e-14 (rank : 133)
Query Neighborhood Hits	349	Target Neighborhood Hits	69	Shared Neighborhood Hits	68
SwissProt Accessions	Q5FWI2, Q80T66	Gene names	Sctr
Domain Architecture	No domain graphic available
Description	Secretin receptor precursor (SCT-R).

GLR_HUMAN
NC score	0.400065 (rank : 203)	θ value	9.59137e-10 (rank : 169)
Query Neighborhood Hits	349	Target Neighborhood Hits	77	Shared Neighborhood Hits	69
SwissProt Accessions	P47871	Gene names	GCGR
Domain Architecture
Description	Glucagon receptor precursor (GL-R).

GRN_MOUSE
NC score	0.398500 (rank : 204)	θ value	0.0113563 (rank : 233)
Query Neighborhood Hits	349	Target Neighborhood Hits	248	Shared Neighborhood Hits	133
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

AGRIN_HUMAN
NC score	0.395162 (rank : 205)	θ value	0.47712 (rank : 268)
Query Neighborhood Hits	349	Target Neighborhood Hits	582	Shared Neighborhood Hits	219
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

GP123_HUMAN
NC score	0.395120 (rank : 206)	θ value	9.92553e-07 (rank : 195)
Query Neighborhood Hits	349	Target Neighborhood Hits	120	Shared Neighborhood Hits	49
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

GLR_MOUSE
NC score	0.391453 (rank : 207)	θ value	7.34386e-10 (rank : 167)
Query Neighborhood Hits	349	Target Neighborhood Hits	79	Shared Neighborhood Hits	68
SwissProt Accessions	Q61606, Q63960	Gene names	Gcgr
Domain Architecture
Description	Glucagon receptor precursor (GL-R).

PTHR2_HUMAN
NC score	0.391430 (rank : 208)	θ value	1.02475e-11 (rank : 154)
Query Neighborhood Hits	349	Target Neighborhood Hits	81	Shared Neighborhood Hits	66
SwissProt Accessions	P49190, Q8N429	Gene names	PTHR2
Domain Architecture
Description	Parathyroid hormone receptor precursor (PTH2 receptor).

TENA_HUMAN
NC score	0.389629 (rank : 209)	θ value	θ > 10 (rank : 627)
Query Neighborhood Hits	349	Target Neighborhood Hits	631	Shared Neighborhood Hits	219
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

GHRHR_MOUSE
NC score	0.385531 (rank : 210)	θ value	6.21693e-09 (rank : 177)
Query Neighborhood Hits	349	Target Neighborhood Hits	79	Shared Neighborhood Hits	71
SwissProt Accessions	P32082	Gene names	Ghrhr, Grfr
Domain Architecture	No domain graphic available
Description	Growth hormone-releasing hormone receptor precursor (GHRH receptor) (GRF receptor) (GRFR).

PTHR2_MOUSE
NC score	0.384461 (rank : 211)	θ value	9.90251e-15 (rank : 125)
Query Neighborhood Hits	349	Target Neighborhood Hits	84	Shared Neighborhood Hits	67
SwissProt Accessions	Q91V95	Gene names	Pthr2
Domain Architecture
Description	Parathyroid hormone receptor precursor (PTH2 receptor).

TENA_MOUSE
NC score	0.383331 (rank : 212)	θ value	θ > 10 (rank : 628)
Query Neighborhood Hits	349	Target Neighborhood Hits	596	Shared Neighborhood Hits	215
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TENX_HUMAN
NC score	0.382815 (rank : 213)	θ value	0.163984 (rank : 254)
Query Neighborhood Hits	349	Target Neighborhood Hits	789	Shared Neighborhood Hits	222
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

GIPR_HUMAN
NC score	0.382271 (rank : 214)	θ value	3.41135e-07 (rank : 192)
Query Neighborhood Hits	349	Target Neighborhood Hits	71	Shared Neighborhood Hits	68
SwissProt Accessions	P48546, Q14401, Q16400, Q9UPI1	Gene names	GIPR
Domain Architecture
Description	Gastric inhibitory polypeptide receptor precursor (GIP-R) (Glucose- dependent insulinotropic polypeptide receptor).

GRN_HUMAN
NC score	0.381345 (rank : 215)	θ value	0.00134147 (rank : 213)
Query Neighborhood Hits	349	Target Neighborhood Hits	268	Shared Neighborhood Hits	133
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

CSPG2_MOUSE
NC score	0.380533 (rank : 216)	θ value	0.00228821 (rank : 217)
Query Neighborhood Hits	349	Target Neighborhood Hits	711	Shared Neighborhood Hits	196
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CSPG2_HUMAN
NC score	0.376299 (rank : 217)	θ value	0.00175202 (rank : 216)
Query Neighborhood Hits	349	Target Neighborhood Hits	681	Shared Neighborhood Hits	192
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

GLP2R_HUMAN
NC score	0.371576 (rank : 218)	θ value	1.17247e-07 (rank : 186)
Query Neighborhood Hits	349	Target Neighborhood Hits	75	Shared Neighborhood Hits	69
SwissProt Accessions	O95838	Gene names	GLP2R
Domain Architecture
Description	Glucagon-like peptide 2 receptor precursor (GLP-2 receptor) (GLP-2-R) (GLP-2R).

CRAC1_HUMAN
NC score	0.364924 (rank : 219)	θ value	1.38821 (rank : 291)
Query Neighborhood Hits	349	Target Neighborhood Hits	111	Shared Neighborhood Hits	98
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRAC1_MOUSE
NC score	0.364617 (rank : 220)	θ value	1.38821 (rank : 292)
Query Neighborhood Hits	349	Target Neighborhood Hits	112	Shared Neighborhood Hits	99
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CSPG3_MOUSE
NC score	0.363945 (rank : 221)	θ value	0.00134147 (rank : 212)
Query Neighborhood Hits	349	Target Neighborhood Hits	657	Shared Neighborhood Hits	193
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CSPG3_HUMAN
NC score	0.358719 (rank : 222)	θ value	0.00102713 (rank : 210)
Query Neighborhood Hits	349	Target Neighborhood Hits	676	Shared Neighborhood Hits	188
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

FATH_HUMAN
NC score	0.344341 (rank : 223)	θ value	3.08544e-08 (rank : 182)
Query Neighborhood Hits	349	Target Neighborhood Hits	570	Shared Neighborhood Hits	222
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

KR106_HUMAN
NC score	0.340049 (rank : 224)	θ value	0.47712 (rank : 271)
Query Neighborhood Hits	349	Target Neighborhood Hits	347	Shared Neighborhood Hits	155
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

PERT_HUMAN
NC score	0.339885 (rank : 225)	θ value	0.365318 (rank : 266)
Query Neighborhood Hits	349	Target Neighborhood Hits	221	Shared Neighborhood Hits	160
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

KR107_HUMAN
NC score	0.339306 (rank : 226)	θ value	5.27518 (rank : 326)
Query Neighborhood Hits	349	Target Neighborhood Hits	330	Shared Neighborhood Hits	147
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KRA53_HUMAN
NC score	0.339259 (rank : 227)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	349	Target Neighborhood Hits	331	Shared Neighborhood Hits	149
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KR104_HUMAN
NC score	0.331624 (rank : 228)	θ value	4.03905 (rank : 317)
Query Neighborhood Hits	349	Target Neighborhood Hits	313	Shared Neighborhood Hits	145
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KRA51_HUMAN
NC score	0.326045 (rank : 229)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	349	Target Neighborhood Hits	288	Shared Neighborhood Hits	134
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

PERT_MOUSE
NC score	0.325816 (rank : 230)	θ value	0.00298849 (rank : 222)
Query Neighborhood Hits	349	Target Neighborhood Hits	221	Shared Neighborhood Hits	156
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

MEGF9_HUMAN
NC score	0.323765 (rank : 231)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	349	Target Neighborhood Hits	557	Shared Neighborhood Hits	180
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

LAMA5_MOUSE
NC score	0.323110 (rank : 232)	θ value	1.06291 (rank : 289)
Query Neighborhood Hits	349	Target Neighborhood Hits	828	Shared Neighborhood Hits	213
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

GP124_MOUSE
NC score	0.321390 (rank : 233)	θ value	4.16044e-13 (rank : 142)
Query Neighborhood Hits	349	Target Neighborhood Hits	423	Shared Neighborhood Hits	61
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

LYAM3_MOUSE
NC score	0.321282 (rank : 234)	θ value	0.000158464 (rank : 204)
Query Neighborhood Hits	349	Target Neighborhood Hits	390	Shared Neighborhood Hits	196
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

GP125_HUMAN
NC score	0.320677 (rank : 235)	θ value	8.95645e-16 (rank : 113)
Query Neighborhood Hits	349	Target Neighborhood Hits	327	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

HHIP_HUMAN
NC score	0.319813 (rank : 236)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	349	Target Neighborhood Hits	249	Shared Neighborhood Hits	133
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HHIP_MOUSE
NC score	0.318303 (rank : 237)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	349	Target Neighborhood Hits	219	Shared Neighborhood Hits	122
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

UROL1_MOUSE
NC score	0.316498 (rank : 238)	θ value	0.163984 (rank : 255)
Query Neighborhood Hits	349	Target Neighborhood Hits	235	Shared Neighborhood Hits	139
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

KRA58_HUMAN
NC score	0.312102 (rank : 239)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	349	Target Neighborhood Hits	324	Shared Neighborhood Hits	138
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

LAMA5_HUMAN
NC score	0.310161 (rank : 240)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	349	Target Neighborhood Hits	976	Shared Neighborhood Hits	213
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

SSPO_MOUSE
NC score	0.309533 (rank : 241)	θ value	5.27518 (rank : 328)
Query Neighborhood Hits	349	Target Neighborhood Hits	800	Shared Neighborhood Hits	212
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

LAMB2_HUMAN
NC score	0.304287 (rank : 242)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	349	Target Neighborhood Hits	692	Shared Neighborhood Hits	189
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

GP125_MOUSE
NC score	0.301856 (rank : 243)	θ value	8.38298e-14 (rank : 135)
Query Neighborhood Hits	349	Target Neighborhood Hits	329	Shared Neighborhood Hits	55
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

UROL1_HUMAN
NC score	0.301833 (rank : 244)	θ value	0.00134147 (rank : 214)
Query Neighborhood Hits	349	Target Neighborhood Hits	213	Shared Neighborhood Hits	130
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

PCSK5_MOUSE
NC score	0.298254 (rank : 245)	θ value	0.47712 (rank : 276)
Query Neighborhood Hits	349	Target Neighborhood Hits	613	Shared Neighborhood Hits	199
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

LAMA1_MOUSE
NC score	0.298241 (rank : 246)	θ value	2.36792 (rank : 308)
Query Neighborhood Hits	349	Target Neighborhood Hits	838	Shared Neighborhood Hits	209
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMC3_MOUSE
NC score	0.297763 (rank : 247)	θ value	0.125558 (rank : 251)
Query Neighborhood Hits	349	Target Neighborhood Hits	624	Shared Neighborhood Hits	187
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

GP124_HUMAN
NC score	0.297562 (rank : 248)	θ value	1.86753e-13 (rank : 138)
Query Neighborhood Hits	349	Target Neighborhood Hits	304	Shared Neighborhood Hits	56
SwissProt Accessions	Q96PE1, Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4	Gene names	GPR124, KIAA1531, TEM5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

MEGF9_MOUSE
NC score	0.296696 (rank : 249)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	349	Target Neighborhood Hits	896	Shared Neighborhood Hits	170
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

BMP1_MOUSE
NC score	0.296525 (rank : 250)	θ value	0.000786445 (rank : 209)
Query Neighborhood Hits	349	Target Neighborhood Hits	236	Shared Neighborhood Hits	172
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

LAMB2_MOUSE
NC score	0.296235 (rank : 251)	θ value	5.27518 (rank : 327)
Query Neighborhood Hits	349	Target Neighborhood Hits	722	Shared Neighborhood Hits	190
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMA1_HUMAN
NC score	0.295381 (rank : 252)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	349	Target Neighborhood Hits	804	Shared Neighborhood Hits	200
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LYAM2_HUMAN
NC score	0.294688 (rank : 253)	θ value	3.19293e-05 (rank : 200)
Query Neighborhood Hits	349	Target Neighborhood Hits	394	Shared Neighborhood Hits	185
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

BMP1_HUMAN
NC score	0.294283 (rank : 254)	θ value	0.000461057 (rank : 207)
Query Neighborhood Hits	349	Target Neighborhood Hits	233	Shared Neighborhood Hits	171
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

LAMC2_MOUSE
NC score	0.292378 (rank : 255)	θ value	0.00869519 (rank : 232)
Query Neighborhood Hits	349	Target Neighborhood Hits	614	Shared Neighborhood Hits	182
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

NAGPA_HUMAN
NC score	0.289634 (rank : 256)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	349	Target Neighborhood Hits	282	Shared Neighborhood Hits	146
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

LYAM3_HUMAN
NC score	0.287722 (rank : 257)	θ value	5.44631e-05 (rank : 201)
Query Neighborhood Hits	349	Target Neighborhood Hits	378	Shared Neighborhood Hits	188
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

ITB6_MOUSE
NC score	0.287185 (rank : 258)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	349	Target Neighborhood Hits	341	Shared Neighborhood Hits	180
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB5_MOUSE
NC score	0.286347 (rank : 259)	θ value	3.0926 (rank : 314)
Query Neighborhood Hits	349	Target Neighborhood Hits	329	Shared Neighborhood Hits	185
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

TLL1_MOUSE
NC score	0.284877 (rank : 260)	θ value	0.00665767 (rank : 230)
Query Neighborhood Hits	349	Target Neighborhood Hits	237	Shared Neighborhood Hits	173
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

LAMC3_HUMAN
NC score	0.283467 (rank : 261)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	349	Target Neighborhood Hits	588	Shared Neighborhood Hits	191
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

NAGPA_MOUSE
NC score	0.282387 (rank : 262)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	349	Target Neighborhood Hits	308	Shared Neighborhood Hits	160
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

TLL2_HUMAN
NC score	0.281088 (rank : 263)	θ value	0.125558 (rank : 252)
Query Neighborhood Hits	349	Target Neighborhood Hits	241	Shared Neighborhood Hits	173
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

CLC14_MOUSE
NC score	0.280093 (rank : 264)	θ value	3.0926 (rank : 313)
Query Neighborhood Hits	349	Target Neighborhood Hits	120	Shared Neighborhood Hits	110
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

LYAM2_MOUSE
NC score	0.279976 (rank : 265)	θ value	0.00390308 (rank : 224)
Query Neighborhood Hits	349	Target Neighborhood Hits	420	Shared Neighborhood Hits	192
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

TLL2_MOUSE
NC score	0.278986 (rank : 266)	θ value	0.0961366 (rank : 248)
Query Neighborhood Hits	349	Target Neighborhood Hits	240	Shared Neighborhood Hits	173
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL1_HUMAN
NC score	0.277576 (rank : 267)	θ value	0.0148317 (rank : 234)
Query Neighborhood Hits	349	Target Neighborhood Hits	236	Shared Neighborhood Hits	170
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

ITB5_HUMAN
NC score	0.275869 (rank : 268)	θ value	0.0193708 (rank : 235)
Query Neighborhood Hits	349	Target Neighborhood Hits	310	Shared Neighborhood Hits	179
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

SORL_HUMAN
NC score	0.274554 (rank : 269)	θ value	2.36792 (rank : 310)
Query Neighborhood Hits	349	Target Neighborhood Hits	440	Shared Neighborhood Hits	162
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

MFGM_MOUSE
NC score	0.274185 (rank : 270)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	349	Target Neighborhood Hits	233	Shared Neighborhood Hits	136
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

SORL_MOUSE
NC score	0.273849 (rank : 271)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	349	Target Neighborhood Hits	439	Shared Neighborhood Hits	161
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

CRIM1_HUMAN
NC score	0.272442 (rank : 272)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	349	Target Neighborhood Hits	362	Shared Neighborhood Hits	127
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

LAMA2_HUMAN
NC score	0.271704 (rank : 273)	θ value	1.38821 (rank : 296)
Query Neighborhood Hits	349	Target Neighborhood Hits	1092	Shared Neighborhood Hits	198
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

KRA59_HUMAN
NC score	0.270261 (rank : 274)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	349	Target Neighborhood Hits	310	Shared Neighborhood Hits	128
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

LAMC1_MOUSE
NC score	0.269907 (rank : 275)	θ value	1.38821 (rank : 297)
Query Neighborhood Hits	349	Target Neighborhood Hits	856	Shared Neighborhood Hits	189
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC2_HUMAN
NC score	0.269532 (rank : 276)	θ value	0.00228821 (rank : 219)
Query Neighborhood Hits	349	Target Neighborhood Hits	715	Shared Neighborhood Hits	176
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

CLC14_HUMAN
NC score	0.269222 (rank : 277)	θ value	0.47712 (rank : 269)
Query Neighborhood Hits	349	Target Neighborhood Hits	143	Shared Neighborhood Hits	114
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

KR101_HUMAN
NC score	0.267020 (rank : 278)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	349	Target Neighborhood Hits	261	Shared Neighborhood Hits	120
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

LAMC1_HUMAN
NC score	0.266239 (rank : 279)	θ value	0.0431538 (rank : 241)
Query Neighborhood Hits	349	Target Neighborhood Hits	922	Shared Neighborhood Hits	189
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

ITB6_HUMAN
NC score	0.265798 (rank : 280)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	349	Target Neighborhood Hits	318	Shared Neighborhood Hits	170
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

LAMB1_MOUSE
NC score	0.264725 (rank : 281)	θ value	0.62314 (rank : 279)
Query Neighborhood Hits	349	Target Neighborhood Hits	919	Shared Neighborhood Hits	185
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

KRA57_HUMAN
NC score	0.262294 (rank : 282)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	349	Target Neighborhood Hits	269	Shared Neighborhood Hits	121
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

ITB3_HUMAN
NC score	0.262161 (rank : 283)	θ value	0.365318 (rank : 264)
Query Neighborhood Hits	349	Target Neighborhood Hits	325	Shared Neighborhood Hits	184
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

FRAS1_HUMAN
NC score	0.260579 (rank : 284)	θ value	0.0330416 (rank : 237)
Query Neighborhood Hits	349	Target Neighborhood Hits	759	Shared Neighborhood Hits	181
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

CFC1_HUMAN
NC score	0.257632 (rank : 285)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	349	Target Neighborhood Hits	148	Shared Neighborhood Hits	98
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

PGBM_MOUSE
NC score	0.256945 (rank : 286)	θ value	1.81305 (rank : 304)
Query Neighborhood Hits	349	Target Neighborhood Hits	1073	Shared Neighborhood Hits	223
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

LAMB1_HUMAN
NC score	0.256629 (rank : 287)	θ value	0.279714 (rank : 261)
Query Neighborhood Hits	349	Target Neighborhood Hits	1018	Shared Neighborhood Hits	189
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

FA10_MOUSE
NC score	0.255015 (rank : 288)	θ value	0.00298849 (rank : 221)
Query Neighborhood Hits	349	Target Neighborhood Hits	435	Shared Neighborhood Hits	218
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

PGBM_HUMAN
NC score	0.254939 (rank : 289)	θ value	1.38821 (rank : 301)
Query Neighborhood Hits	349	Target Neighborhood Hits	1113	Shared Neighborhood Hits	226
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

KRA55_HUMAN
NC score	0.254168 (rank : 290)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	349	Target Neighborhood Hits	257	Shared Neighborhood Hits	115
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

NTNG2_MOUSE
NC score	0.254160 (rank : 291)	θ value	θ > 10 (rank : 578)
Query Neighborhood Hits	349	Target Neighborhood Hits	276	Shared Neighborhood Hits	161
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

LAMA2_MOUSE
NC score	0.251146 (rank : 292)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	349	Target Neighborhood Hits	1198	Shared Neighborhood Hits	195
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

FA10_HUMAN
NC score	0.249531 (rank : 293)	θ value	0.00509761 (rank : 225)
Query Neighborhood Hits	349	Target Neighborhood Hits	431	Shared Neighborhood Hits	215
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FRAS1_MOUSE
NC score	0.247970 (rank : 294)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	349	Target Neighborhood Hits	747	Shared Neighborhood Hits	170
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

ZAN_HUMAN
NC score	0.245180 (rank : 295)	θ value	0.365318 (rank : 267)
Query Neighborhood Hits	349	Target Neighborhood Hits	679	Shared Neighborhood Hits	194
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ITB2_MOUSE
NC score	0.244919 (rank : 296)	θ value	0.0736092 (rank : 246)
Query Neighborhood Hits	349	Target Neighborhood Hits	326	Shared Neighborhood Hits	176
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

CFC1_MOUSE
NC score	0.244813 (rank : 297)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	349	Target Neighborhood Hits	125	Shared Neighborhood Hits	86
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

MATN1_HUMAN
NC score	0.244328 (rank : 298)	θ value	1.38821 (rank : 300)
Query Neighborhood Hits	349	Target Neighborhood Hits	191	Shared Neighborhood Hits	138
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN1_MOUSE
NC score	0.243689 (rank : 299)	θ value	4.03905 (rank : 318)
Query Neighborhood Hits	349	Target Neighborhood Hits	186	Shared Neighborhood Hits	133
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

ITB7_HUMAN
NC score	0.243593 (rank : 300)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	349	Target Neighborhood Hits	290	Shared Neighborhood Hits	163
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

ITB3_MOUSE
NC score	0.242921 (rank : 301)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	349	Target Neighborhood Hits	319	Shared Neighborhood Hits	177
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

KRA54_HUMAN
NC score	0.242597 (rank : 302)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	349	Target Neighborhood Hits	270	Shared Neighborhood Hits	110
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KR105_HUMAN
NC score	0.241293 (rank : 303)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	349	Target Neighborhood Hits	271	Shared Neighborhood Hits	119
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

LAMA3_MOUSE
NC score	0.241167 (rank : 304)	θ value	6.88961 (rank : 335)
Query Neighborhood Hits	349	Target Neighborhood Hits	859	Shared Neighborhood Hits	203
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LRP6_HUMAN
NC score	0.240688 (rank : 305)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	349	Target Neighborhood Hits	235	Shared Neighborhood Hits	147
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

NTNG2_HUMAN
NC score	0.240581 (rank : 306)	θ value	θ > 10 (rank : 577)
Query Neighborhood Hits	349	Target Neighborhood Hits	276	Shared Neighborhood Hits	156
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

ITB7_MOUSE
NC score	0.240029 (rank : 307)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	349	Target Neighborhood Hits	277	Shared Neighborhood Hits	154
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

LAMB3_MOUSE
NC score	0.239429 (rank : 308)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	349	Target Neighborhood Hits	444	Shared Neighborhood Hits	153
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

KR102_HUMAN
NC score	0.239342 (rank : 309)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	349	Target Neighborhood Hits	264	Shared Neighborhood Hits	116
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

USH2A_MOUSE
NC score	0.239288 (rank : 310)	θ value	θ > 10 (rank : 664)
Query Neighborhood Hits	349	Target Neighborhood Hits	626	Shared Neighborhood Hits	174
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

KR171_HUMAN
NC score	0.238815 (rank : 311)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	349	Target Neighborhood Hits	144	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

LRP6_MOUSE
NC score	0.238318 (rank : 312)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	349	Target Neighborhood Hits	232	Shared Neighborhood Hits	146
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

ITB1_MOUSE
NC score	0.236626 (rank : 313)	θ value	5.27518 (rank : 325)
Query Neighborhood Hits	349	Target Neighborhood Hits	283	Shared Neighborhood Hits	150
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB4_HUMAN
NC score	0.234757 (rank : 314)	θ value	1.38821 (rank : 295)
Query Neighborhood Hits	349	Target Neighborhood Hits	458	Shared Neighborhood Hits	162
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

KR511_HUMAN
NC score	0.231905 (rank : 315)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	349	Target Neighborhood Hits	231	Shared Neighborhood Hits	105
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

TDGF1_MOUSE
NC score	0.231572 (rank : 316)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	349	Target Neighborhood Hits	146	Shared Neighborhood Hits	102
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

PROC_MOUSE
NC score	0.231300 (rank : 317)	θ value	0.21417 (rank : 257)
Query Neighborhood Hits	349	Target Neighborhood Hits	426	Shared Neighborhood Hits	201
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

FA9_HUMAN
NC score	0.230251 (rank : 318)	θ value	0.47712 (rank : 270)
Query Neighborhood Hits	349	Target Neighborhood Hits	421	Shared Neighborhood Hits	207
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

MUC13_MOUSE
NC score	0.229422 (rank : 319)	θ value	0.365318 (rank : 265)
Query Neighborhood Hits	349	Target Neighborhood Hits	447	Shared Neighborhood Hits	140
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

LRP5_MOUSE
NC score	0.229417 (rank : 320)	θ value	0.47712 (rank : 273)
Query Neighborhood Hits	349	Target Neighborhood Hits	236	Shared Neighborhood Hits	135
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

TENR_MOUSE
NC score	0.229325 (rank : 321)	θ value	θ > 10 (rank : 632)
Query Neighborhood Hits	349	Target Neighborhood Hits	531	Shared Neighborhood Hits	183
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

ITB2_HUMAN
NC score	0.227640 (rank : 322)	θ value	0.00665767 (rank : 228)
Query Neighborhood Hits	349	Target Neighborhood Hits	282	Shared Neighborhood Hits	153
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

HABP2_HUMAN
NC score	0.226469 (rank : 323)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	349	Target Neighborhood Hits	431	Shared Neighborhood Hits	187
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

LRP5_HUMAN
NC score	0.223509 (rank : 324)	θ value	0.47712 (rank : 272)
Query Neighborhood Hits	349	Target Neighborhood Hits	224	Shared Neighborhood Hits	133
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

KR109_HUMAN
NC score	0.223216 (rank : 325)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	349	Target Neighborhood Hits	226	Shared Neighborhood Hits	105
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

HABP2_MOUSE
NC score	0.223095 (rank : 326)	θ value	6.88961 (rank : 331)
Query Neighborhood Hits	349	Target Neighborhood Hits	445	Shared Neighborhood Hits	190
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

TENR_HUMAN
NC score	0.222835 (rank : 327)	θ value	θ > 10 (rank : 631)
Query Neighborhood Hits	349	Target Neighborhood Hits	526	Shared Neighborhood Hits	178
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

ITB1_HUMAN
NC score	0.221040 (rank : 328)	θ value	1.38821 (rank : 294)
Query Neighborhood Hits	349	Target Neighborhood Hits	298	Shared Neighborhood Hits	153
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

LYAM1_HUMAN
NC score	0.220794 (rank : 329)	θ value	1.38821 (rank : 298)
Query Neighborhood Hits	349	Target Neighborhood Hits	315	Shared Neighborhood Hits	147
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

USH2A_HUMAN
NC score	0.219652 (rank : 330)	θ value	θ > 10 (rank : 663)
Query Neighborhood Hits	349	Target Neighborhood Hits	600	Shared Neighborhood Hits	163
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

NTNG1_MOUSE
NC score	0.218707 (rank : 331)	θ value	θ > 10 (rank : 576)
Query Neighborhood Hits	349	Target Neighborhood Hits	246	Shared Neighborhood Hits	137
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG1_HUMAN
NC score	0.216905 (rank : 332)	θ value	θ > 10 (rank : 575)
Query Neighborhood Hits	349	Target Neighborhood Hits	247	Shared Neighborhood Hits	137
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

PHXR5_MOUSE
NC score	0.216790 (rank : 333)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	349	Target Neighborhood Hits	102	Shared Neighborhood Hits	73
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

PROC_HUMAN
NC score	0.216280 (rank : 334)	θ value	0.00228821 (rank : 220)
Query Neighborhood Hits	349	Target Neighborhood Hits	406	Shared Neighborhood Hits	195
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

FA7_HUMAN
NC score	0.215460 (rank : 335)	θ value	1.06291 (rank : 287)
Query Neighborhood Hits	349	Target Neighborhood Hits	404	Shared Neighborhood Hits	198
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

LAMA4_MOUSE
NC score	0.214330 (rank : 336)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	349	Target Neighborhood Hits	584	Shared Neighborhood Hits	157
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LYAM1_MOUSE
NC score	0.213219 (rank : 337)	θ value	1.38821 (rank : 299)
Query Neighborhood Hits	349	Target Neighborhood Hits	332	Shared Neighborhood Hits	151
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

KR108_HUMAN
NC score	0.212947 (rank : 338)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	349	Target Neighborhood Hits	226	Shared Neighborhood Hits	106
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

LAMB3_HUMAN
NC score	0.212427 (rank : 339)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	349	Target Neighborhood Hits	461	Shared Neighborhood Hits	131
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

KR10C_HUMAN
NC score	0.210302 (rank : 340)	θ value	6.88961 (rank : 334)
Query Neighborhood Hits	349	Target Neighborhood Hits	219	Shared Neighborhood Hits	102
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KRA56_HUMAN
NC score	0.209750 (rank : 341)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	349	Target Neighborhood Hits	207	Shared Neighborhood Hits	97
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA52_HUMAN
NC score	0.207238 (rank : 342)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	349	Target Neighborhood Hits	236	Shared Neighborhood Hits	103
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

LAMA3_HUMAN
NC score	0.207129 (rank : 343)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	349	Target Neighborhood Hits	760	Shared Neighborhood Hits	170
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

ATRN_MOUSE
NC score	0.205329 (rank : 344)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	349	Target Neighborhood Hits	519	Shared Neighborhood Hits	167
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

ATRN_HUMAN
NC score	0.205315 (rank : 345)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	349	Target Neighborhood Hits	525	Shared Neighborhood Hits	170
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

FAT2_HUMAN
NC score	0.201527 (rank : 346)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	349	Target Neighborhood Hits	507	Shared Neighborhood Hits	160
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

LAMA4_HUMAN
NC score	0.200480 (rank : 347)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	349	Target Neighborhood Hits	708	Shared Neighborhood Hits	156
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

TDGF2_HUMAN
NC score	0.197886 (rank : 348)	θ value	θ > 10 (rank : 626)
Query Neighborhood Hits	349	Target Neighborhood Hits	131	Shared Neighborhood Hits	90
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

TDGF1_HUMAN
NC score	0.197842 (rank : 349)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	349	Target Neighborhood Hits	132	Shared Neighborhood Hits	93
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

KR10B_HUMAN
NC score	0.195380 (rank : 350)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	349	Target Neighborhood Hits	269	Shared Neighborhood Hits	111
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

GP157_HUMAN
NC score	0.190099 (rank : 351)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	349	Target Neighborhood Hits	93	Shared Neighborhood Hits	50
SwissProt Accessions	Q5UAW9, Q8WWB8, Q9HA73	Gene names	GPR157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

KRA13_HUMAN
NC score	0.188179 (rank : 352)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	349	Target Neighborhood Hits	144	Shared Neighborhood Hits	71
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

MUC5B_HUMAN
NC score	0.187268 (rank : 353)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	349	Target Neighborhood Hits	1020	Shared Neighborhood Hits	171
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

TEFF2_MOUSE
NC score	0.186260 (rank : 354)	θ value	8.99809 (rank : 349)
Query Neighborhood Hits	349	Target Neighborhood Hits	214	Shared Neighborhood Hits	100
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

ITB8_HUMAN
NC score	0.185640 (rank : 355)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	349	Target Neighborhood Hits	280	Shared Neighborhood Hits	154
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

TEFF2_HUMAN
NC score	0.185639 (rank : 356)	θ value	2.36792 (rank : 311)
Query Neighborhood Hits	349	Target Neighborhood Hits	211	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TECTA_MOUSE
NC score	0.182969 (rank : 357)	θ value	8.99809 (rank : 348)
Query Neighborhood Hits	349	Target Neighborhood Hits	244	Shared Neighborhood Hits	141
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

VWF_HUMAN
NC score	0.182527 (rank : 358)	θ value	θ > 10 (rank : 667)
Query Neighborhood Hits	349	Target Neighborhood Hits	396	Shared Neighborhood Hits	142
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

GP157_MOUSE
NC score	0.181918 (rank : 359)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	349	Target Neighborhood Hits	78	Shared Neighborhood Hits	49
SwissProt Accessions	Q8C206, Q8C224	Gene names	Gpr157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

TENN_MOUSE
NC score	0.181246 (rank : 360)	θ value	θ > 10 (rank : 630)
Query Neighborhood Hits	349	Target Neighborhood Hits	484	Shared Neighborhood Hits	160
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

PGCB_MOUSE
NC score	0.179416 (rank : 361)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	349	Target Neighborhood Hits	459	Shared Neighborhood Hits	145
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

KRA98_HUMAN
NC score	0.177372 (rank : 362)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	349	Target Neighborhood Hits	185	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

FA7_MOUSE
NC score	0.177176 (rank : 363)	θ value	8.99809 (rank : 346)
Query Neighborhood Hits	349	Target Neighborhood Hits	374	Shared Neighborhood Hits	177
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

LCE1B_HUMAN
NC score	0.176266 (rank : 364)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	349	Target Neighborhood Hits	58	Shared Neighborhood Hits	31
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

KRA45_HUMAN
NC score	0.173273 (rank : 365)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	349	Target Neighborhood Hits	194	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

KRA44_HUMAN
NC score	0.172699 (rank : 366)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	349	Target Neighborhood Hits	162	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KR414_HUMAN
NC score	0.171538 (rank : 367)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	349	Target Neighborhood Hits	199	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

VWF_MOUSE
NC score	0.171441 (rank : 368)	θ value	θ > 10 (rank : 668)
Query Neighborhood Hits	349	Target Neighborhood Hits	381	Shared Neighborhood Hits	132
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

KRA94_HUMAN
NC score	0.171388 (rank : 369)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	349	Target Neighborhood Hits	204	Shared Neighborhood Hits	83
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KRA93_HUMAN
NC score	0.170316 (rank : 370)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	349	Target Neighborhood Hits	203	Shared Neighborhood Hits	73
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KR510_HUMAN
NC score	0.169964 (rank : 371)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	349	Target Neighborhood Hits	217	Shared Neighborhood Hits	88
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

HGFA_HUMAN
NC score	0.169869 (rank : 372)	θ value	6.88961 (rank : 332)
Query Neighborhood Hits	349	Target Neighborhood Hits	436	Shared Neighborhood Hits	173
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

LCE1D_HUMAN
NC score	0.169283 (rank : 373)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	349	Target Neighborhood Hits	44	Shared Neighborhood Hits	24
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

HGFA_MOUSE
NC score	0.168747 (rank : 374)	θ value	5.27518 (rank : 324)
Query Neighborhood Hits	349	Target Neighborhood Hits	419	Shared Neighborhood Hits	179
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

NFX1_HUMAN
NC score	0.168146 (rank : 375)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	349	Target Neighborhood Hits	405	Shared Neighborhood Hits	101
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

ASTN_HUMAN
NC score	0.166469 (rank : 376)	θ value	5.27518 (rank : 322)
Query Neighborhood Hits	349	Target Neighborhood Hits	105	Shared Neighborhood Hits	78
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

TENN_HUMAN
NC score	0.165237 (rank : 377)	θ value	θ > 10 (rank : 629)
Query Neighborhood Hits	349	Target Neighborhood Hits	453	Shared Neighborhood Hits	159
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TECTA_HUMAN
NC score	0.164915 (rank : 378)	θ value	5.27518 (rank : 329)
Query Neighborhood Hits	349	Target Neighborhood Hits	239	Shared Neighborhood Hits	131
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

KR10A_HUMAN
NC score	0.164802 (rank : 379)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	349	Target Neighborhood Hits	232	Shared Neighborhood Hits	99
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

KRA99_HUMAN
NC score	0.164170 (rank : 380)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	349	Target Neighborhood Hits	173	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

PGCB_HUMAN
NC score	0.163603 (rank : 381)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	349	Target Neighborhood Hits	478	Shared Neighborhood Hits	139
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

MEP1A_MOUSE
NC score	0.161308 (rank : 382)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	349	Target Neighborhood Hits	166	Shared Neighborhood Hits	114
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

C1RA_MOUSE
NC score	0.161261 (rank : 383)	θ value	0.0431538 (rank : 238)
Query Neighborhood Hits	349	Target Neighborhood Hits	379	Shared Neighborhood Hits	159
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

MEP1A_HUMAN
NC score	0.160559 (rank : 384)	θ value	4.03905 (rank : 319)
Query Neighborhood Hits	349	Target Neighborhood Hits	162	Shared Neighborhood Hits	113
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

C1RB_MOUSE
NC score	0.159070 (rank : 385)	θ value	0.0431538 (rank : 239)
Query Neighborhood Hits	349	Target Neighborhood Hits	380	Shared Neighborhood Hits	159
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

LCE1C_HUMAN
NC score	0.159032 (rank : 386)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	349	Target Neighborhood Hits	65	Shared Neighborhood Hits	33
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

ASTN_MOUSE
NC score	0.158745 (rank : 387)	θ value	5.27518 (rank : 323)
Query Neighborhood Hits	349	Target Neighborhood Hits	98	Shared Neighborhood Hits	74
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

KRA92_HUMAN
NC score	0.157623 (rank : 388)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	349	Target Neighborhood Hits	198	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

NRX1A_HUMAN
NC score	0.155585 (rank : 389)	θ value	θ > 10 (rank : 571)
Query Neighborhood Hits	349	Target Neighborhood Hits	170	Shared Neighborhood Hits	99
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
NC score	0.155515 (rank : 390)	θ value	θ > 10 (rank : 572)
Query Neighborhood Hits	349	Target Neighborhood Hits	164	Shared Neighborhood Hits	98
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

FA12_HUMAN
NC score	0.154333 (rank : 391)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	349	Target Neighborhood Hits	425	Shared Neighborhood Hits	169
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

KR103_HUMAN
NC score	0.153759 (rank : 392)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	349	Target Neighborhood Hits	212	Shared Neighborhood Hits	81
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

CNTP2_MOUSE
NC score	0.153251 (rank : 393)	θ value	8.99809 (rank : 344)
Query Neighborhood Hits	349	Target Neighborhood Hits	194	Shared Neighborhood Hits	111
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

KR412_HUMAN
NC score	0.152916 (rank : 394)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	349	Target Neighborhood Hits	178	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KRA11_HUMAN
NC score	0.152520 (rank : 395)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	349	Target Neighborhood Hits	155	Shared Neighborhood Hits	73
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

KRA15_HUMAN
NC score	0.151612 (rank : 396)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	349	Target Neighborhood Hits	126	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

PCSK5_HUMAN
NC score	0.151324 (rank : 397)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	349	Target Neighborhood Hits	291	Shared Neighborhood Hits	134
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

CNTP2_HUMAN
NC score	0.150006 (rank : 398)	θ value	8.99809 (rank : 343)
Query Neighborhood Hits	349	Target Neighborhood Hits	199	Shared Neighborhood Hits	114
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CO6_HUMAN
NC score	0.149561 (rank : 399)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	349	Target Neighborhood Hits	331	Shared Neighborhood Hits	132
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

NRX3A_HUMAN
NC score	0.149353 (rank : 400)	θ value	θ > 10 (rank : 574)
Query Neighborhood Hits	349	Target Neighborhood Hits	164	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

C1R_HUMAN
NC score	0.149121 (rank : 401)	θ value	0.813845 (rank : 282)
Query Neighborhood Hits	349	Target Neighborhood Hits	364	Shared Neighborhood Hits	148
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

KRA47_HUMAN
NC score	0.148634 (rank : 402)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	349	Target Neighborhood Hits	204	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

MMRN1_HUMAN
NC score	0.148550 (rank : 403)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	349	Target Neighborhood Hits	636	Shared Neighborhood Hits	114
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

MUC13_HUMAN
NC score	0.147559 (rank : 404)	θ value	0.47712 (rank : 275)
Query Neighborhood Hits	349	Target Neighborhood Hits	164	Shared Neighborhood Hits	84
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

NET2_HUMAN
NC score	0.146543 (rank : 405)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	349	Target Neighborhood Hits	194	Shared Neighborhood Hits	108
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

CO7_HUMAN
NC score	0.145137 (rank : 406)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	349	Target Neighborhood Hits	278	Shared Neighborhood Hits	117
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CNTP3_HUMAN
NC score	0.144280 (rank : 407)	θ value	0.125558 (rank : 249)
Query Neighborhood Hits	349	Target Neighborhood Hits	195	Shared Neighborhood Hits	99
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

NET2_MOUSE
NC score	0.144236 (rank : 408)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	349	Target Neighborhood Hits	193	Shared Neighborhood Hits	109
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

NRX2A_HUMAN
NC score	0.144133 (rank : 409)	θ value	θ > 10 (rank : 573)
Query Neighborhood Hits	349	Target Neighborhood Hits	614	Shared Neighborhood Hits	105
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

PGCA_HUMAN
NC score	0.143258 (rank : 410)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	349	Target Neighborhood Hits	821	Shared Neighborhood Hits	142
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

MFGM_HUMAN
NC score	0.141276 (rank : 411)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	349	Target Neighborhood Hits	150	Shared Neighborhood Hits	99
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

CORIN_HUMAN
NC score	0.139233 (rank : 412)	θ value	0.00665767 (rank : 227)
Query Neighborhood Hits	349	Target Neighborhood Hits	453	Shared Neighborhood Hits	164
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

LCE1E_HUMAN
NC score	0.138981 (rank : 413)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	349	Target Neighborhood Hits	53	Shared Neighborhood Hits	24
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

CNTP4_HUMAN
NC score	0.138212 (rank : 414)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	349	Target Neighborhood Hits	187	Shared Neighborhood Hits	93
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

NET4_HUMAN
NC score	0.138191 (rank : 415)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	349	Target Neighborhood Hits	191	Shared Neighborhood Hits	104
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

CS1A_MOUSE
NC score	0.137282 (rank : 416)	θ value	0.125558 (rank : 250)
Query Neighborhood Hits	349	Target Neighborhood Hits	360	Shared Neighborhood Hits	140
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CNTP4_MOUSE
NC score	0.137188 (rank : 417)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	349	Target Neighborhood Hits	193	Shared Neighborhood Hits	109
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

MASP2_HUMAN
NC score	0.136413 (rank : 418)	θ value	0.21417 (rank : 256)
Query Neighborhood Hits	349	Target Neighborhood Hits	364	Shared Neighborhood Hits	143
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

CS1B_MOUSE
NC score	0.136323 (rank : 419)	θ value	0.0563607 (rank : 243)
Query Neighborhood Hits	349	Target Neighborhood Hits	361	Shared Neighborhood Hits	140
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

MASP2_MOUSE
NC score	0.134856 (rank : 420)	θ value	0.0563607 (rank : 244)
Query Neighborhood Hits	349	Target Neighborhood Hits	382	Shared Neighborhood Hits	150
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

NRG4_HUMAN
NC score	0.133159 (rank : 421)	θ value	θ > 10 (rank : 565)
Query Neighborhood Hits	349	Target Neighborhood Hits	85	Shared Neighborhood Hits	52
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

LRP3_HUMAN
NC score	0.132609 (rank : 422)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	349	Target Neighborhood Hits	280	Shared Neighborhood Hits	102
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

RELN_MOUSE
NC score	0.132011 (rank : 423)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	349	Target Neighborhood Hits	235	Shared Neighborhood Hits	124
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

C1S_HUMAN
NC score	0.131996 (rank : 424)	θ value	0.0431538 (rank : 240)
Query Neighborhood Hits	349	Target Neighborhood Hits	359	Shared Neighborhood Hits	145
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

MASP1_HUMAN
NC score	0.131204 (rank : 425)	θ value	0.47712 (rank : 274)
Query Neighborhood Hits	349	Target Neighborhood Hits	369	Shared Neighborhood Hits	144
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

CO8B_MOUSE
NC score	0.131161 (rank : 426)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	349	Target Neighborhood Hits	224	Shared Neighborhood Hits	92
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

NET4_MOUSE
NC score	0.131037 (rank : 427)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	349	Target Neighborhood Hits	180	Shared Neighborhood Hits	102
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

CNTP1_HUMAN
NC score	0.128445 (rank : 428)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	349	Target Neighborhood Hits	196	Shared Neighborhood Hits	97
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

MASP1_MOUSE
NC score	0.128319 (rank : 429)	θ value	0.62314 (rank : 280)
Query Neighborhood Hits	349	Target Neighborhood Hits	364	Shared Neighborhood Hits	146
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

NRG2_MOUSE
NC score	0.127910 (rank : 430)	θ value	θ > 10 (rank : 564)
Query Neighborhood Hits	349	Target Neighborhood Hits	392	Shared Neighborhood Hits	89
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

PROP_MOUSE
NC score	0.127060 (rank : 431)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	349	Target Neighborhood Hits	165	Shared Neighborhood Hits	33
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

NRG1_HUMAN
NC score	0.127059 (rank : 432)	θ value	θ > 10 (rank : 562)
Query Neighborhood Hits	349	Target Neighborhood Hits	285	Shared Neighborhood Hits	76
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

RELN_HUMAN
NC score	0.126976 (rank : 433)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	349	Target Neighborhood Hits	233	Shared Neighborhood Hits	123
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

RECK_HUMAN
NC score	0.126904 (rank : 434)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	349	Target Neighborhood Hits	189	Shared Neighborhood Hits	85
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

SMDF_HUMAN
NC score	0.125706 (rank : 435)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	349	Target Neighborhood Hits	117	Shared Neighborhood Hits	55
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

ST14_MOUSE
NC score	0.124197 (rank : 436)	θ value	0.0736092 (rank : 247)
Query Neighborhood Hits	349	Target Neighborhood Hits	419	Shared Neighborhood Hits	144
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

PGH2_MOUSE
NC score	0.123591 (rank : 437)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	349	Target Neighborhood Hits	113	Shared Neighborhood Hits	80
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

CNTP1_MOUSE
NC score	0.122207 (rank : 438)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	349	Target Neighborhood Hits	183	Shared Neighborhood Hits	91
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

ST14_HUMAN
NC score	0.122168 (rank : 439)	θ value	0.0563607 (rank : 245)
Query Neighborhood Hits	349	Target Neighborhood Hits	409	Shared Neighborhood Hits	143
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

CORIN_MOUSE
NC score	0.121555 (rank : 440)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	349	Target Neighborhood Hits	451	Shared Neighborhood Hits	156
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

LCE1F_HUMAN
NC score	0.118217 (rank : 441)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	349	Target Neighborhood Hits	48	Shared Neighborhood Hits	22
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

MUC2_HUMAN
NC score	0.117126 (rank : 442)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	349	Target Neighborhood Hits	906	Shared Neighborhood Hits	124
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

BMPER_MOUSE
NC score	0.115949 (rank : 443)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	349	Target Neighborhood Hits	194	Shared Neighborhood Hits	84
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

LCE1A_HUMAN
NC score	0.115849 (rank : 444)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	349	Target Neighborhood Hits	47	Shared Neighborhood Hits	25
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

PROP_HUMAN
NC score	0.115131 (rank : 445)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	349	Target Neighborhood Hits	126	Shared Neighborhood Hits	25
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

TNR25_HUMAN
NC score	0.114399 (rank : 446)	θ value	θ > 10 (rank : 647)
Query Neighborhood Hits	349	Target Neighborhood Hits	172	Shared Neighborhood Hits	59
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

PCSK6_HUMAN
NC score	0.113720 (rank : 447)	θ value	θ > 10 (rank : 593)
Query Neighborhood Hits	349	Target Neighborhood Hits	298	Shared Neighborhood Hits	102
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

PGH1_MOUSE
NC score	0.113305 (rank : 448)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	349	Target Neighborhood Hits	100	Shared Neighborhood Hits	69
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

NRG4_MOUSE
NC score	0.112801 (rank : 449)	θ value	θ > 10 (rank : 566)
Query Neighborhood Hits	349	Target Neighborhood Hits	79	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

LRP12_MOUSE
NC score	0.110957 (rank : 450)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	349	Target Neighborhood Hits	180	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

BMPER_HUMAN
NC score	0.110911 (rank : 451)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	349	Target Neighborhood Hits	175	Shared Neighborhood Hits	73
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

LRP12_HUMAN
NC score	0.110387 (rank : 452)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	349	Target Neighborhood Hits	205	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

CO8B_HUMAN
NC score	0.109970 (rank : 453)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	349	Target Neighborhood Hits	199	Shared Neighborhood Hits	81
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

PGH2_HUMAN
NC score	0.109806 (rank : 454)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	349	Target Neighborhood Hits	103	Shared Neighborhood Hits	72
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

NET1_HUMAN
NC score	0.109609 (rank : 455)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	349	Target Neighborhood Hits	149	Shared Neighborhood Hits	78
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

APR3_MOUSE
NC score	0.109503 (rank : 456)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	349	Target Neighborhood Hits	61	Shared Neighborhood Hits	46
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

LCE3A_HUMAN
NC score	0.108244 (rank : 457)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	349	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

TIE1_HUMAN
NC score	0.108097 (rank : 458)	θ value	θ > 10 (rank : 636)
Query Neighborhood Hits	349	Target Neighborhood Hits	1241	Shared Neighborhood Hits	169
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

CD320_HUMAN
NC score	0.106664 (rank : 459)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	349	Target Neighborhood Hits	103	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

TIE1_MOUSE
NC score	0.105751 (rank : 460)	θ value	θ > 10 (rank : 637)
Query Neighborhood Hits	349	Target Neighborhood Hits	1266	Shared Neighborhood Hits	170
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

VASN_HUMAN
NC score	0.105629 (rank : 461)	θ value	θ > 10 (rank : 665)
Query Neighborhood Hits	349	Target Neighborhood Hits	449	Shared Neighborhood Hits	98
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

NET1_MOUSE
NC score	0.104695 (rank : 462)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	349	Target Neighborhood Hits	151	Shared Neighborhood Hits	79
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

FSTL3_HUMAN
NC score	0.104014 (rank : 463)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	349	Target Neighborhood Hits	162	Shared Neighborhood Hits	68
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

KR410_HUMAN
NC score	0.103533 (rank : 464)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	349	Target Neighborhood Hits	156	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

APR3_HUMAN
NC score	0.103062 (rank : 465)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	349	Target Neighborhood Hits	50	Shared Neighborhood Hits	43
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

LORI_MOUSE
NC score	0.102165 (rank : 466)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	349	Target Neighborhood Hits	47	Shared Neighborhood Hits	17
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

VASN_MOUSE
NC score	0.102002 (rank : 467)	θ value	θ > 10 (rank : 666)
Query Neighborhood Hits	349	Target Neighborhood Hits	426	Shared Neighborhood Hits	95
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

RECK_MOUSE
NC score	0.100888 (rank : 468)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	349	Target Neighborhood Hits	158	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

NRG2_HUMAN
NC score	0.099334 (rank : 469)	θ value	θ > 10 (rank : 563)
Query Neighborhood Hits	349	Target Neighborhood Hits	419	Shared Neighborhood Hits	74
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

CO8A_MOUSE
NC score	0.098474 (rank : 470)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	349	Target Neighborhood Hits	182	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

EREG_HUMAN
NC score	0.098170 (rank : 471)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	349	Target Neighborhood Hits	73	Shared Neighborhood Hits	47
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

FSTL3_MOUSE
NC score	0.097061 (rank : 472)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	349	Target Neighborhood Hits	152	Shared Neighborhood Hits	66
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

VEGFC_MOUSE
NC score	0.095906 (rank : 473)	θ value	0.279714 (rank : 262)
Query Neighborhood Hits	349	Target Neighborhood Hits	119	Shared Neighborhood Hits	69
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

TIE2_MOUSE
NC score	0.095615 (rank : 474)	θ value	1.81305 (rank : 305)
Query Neighborhood Hits	349	Target Neighborhood Hits	1204	Shared Neighborhood Hits	176
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

TIE2_HUMAN
NC score	0.095119 (rank : 475)	θ value	θ > 10 (rank : 638)
Query Neighborhood Hits	349	Target Neighborhood Hits	1192	Shared Neighborhood Hits	178
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

CO8A_HUMAN
NC score	0.094682 (rank : 476)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	349	Target Neighborhood Hits	200	Shared Neighborhood Hits	89
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

KRA42_HUMAN
NC score	0.094178 (rank : 477)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	349	Target Neighborhood Hits	149	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

SPON1_MOUSE
NC score	0.094001 (rank : 478)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	349	Target Neighborhood Hits	123	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

SPON1_HUMAN
NC score	0.093694 (rank : 479)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	349	Target Neighborhood Hits	117	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

VEGFC_HUMAN
NC score	0.093549 (rank : 480)	θ value	0.47712 (rank : 277)
Query Neighborhood Hits	349	Target Neighborhood Hits	128	Shared Neighborhood Hits	71
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

ADA11_HUMAN
NC score	0.093123 (rank : 481)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	349	Target Neighborhood Hits	259	Shared Neighborhood Hits	115
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

MEP1B_MOUSE
NC score	0.092944 (rank : 482)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	349	Target Neighborhood Hits	127	Shared Neighborhood Hits	72
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

ADA11_MOUSE
NC score	0.092478 (rank : 483)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	349	Target Neighborhood Hits	263	Shared Neighborhood Hits	116
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

PGH1_HUMAN
NC score	0.092436 (rank : 484)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	349	Target Neighborhood Hits	91	Shared Neighborhood Hits	61
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

LRP10_MOUSE
NC score	0.092202 (rank : 485)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	349	Target Neighborhood Hits	169	Shared Neighborhood Hits	68
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

TPA_HUMAN
NC score	0.091518 (rank : 486)	θ value	θ > 10 (rank : 652)
Query Neighborhood Hits	349	Target Neighborhood Hits	324	Shared Neighborhood Hits	120
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

RSPO3_HUMAN
NC score	0.091486 (rank : 487)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	349	Target Neighborhood Hits	128	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

LCE4A_HUMAN
NC score	0.091369 (rank : 488)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	349	Target Neighborhood Hits	26	Shared Neighborhood Hits	15
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

CO9_MOUSE
NC score	0.091177 (rank : 489)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	349	Target Neighborhood Hits	153	Shared Neighborhood Hits	72
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

KR413_HUMAN
NC score	0.090854 (rank : 490)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	349	Target Neighborhood Hits	112	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

TPA_MOUSE
NC score	0.089974 (rank : 491)	θ value	θ > 10 (rank : 653)
Query Neighborhood Hits	349	Target Neighborhood Hits	335	Shared Neighborhood Hits	127
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

ADA23_HUMAN
NC score	0.088417 (rank : 492)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	349	Target Neighborhood Hits	235	Shared Neighborhood Hits	114
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

LRP10_HUMAN
NC score	0.088227 (rank : 493)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	349	Target Neighborhood Hits	197	Shared Neighborhood Hits	66
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

MKS3_HUMAN
NC score	0.087976 (rank : 494)	θ value	8.99809 (rank : 347)
Query Neighborhood Hits	349	Target Neighborhood Hits	79	Shared Neighborhood Hits	49
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

ADA10_HUMAN
NC score	0.087405 (rank : 495)	θ value	0.279714 (rank : 259)
Query Neighborhood Hits	349	Target Neighborhood Hits	189	Shared Neighborhood Hits	72
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ADAM8_MOUSE
NC score	0.087139 (rank : 496)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	349	Target Neighborhood Hits	326	Shared Neighborhood Hits	109
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

WFDC3_HUMAN
NC score	0.086510 (rank : 497)	θ value	θ > 10 (rank : 669)
Query Neighborhood Hits	349	Target Neighborhood Hits	138	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

ESM1_HUMAN
NC score	0.085761 (rank : 498)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	349	Target Neighborhood Hits	110	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

ADA23_MOUSE
NC score	0.085135 (rank : 499)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	349	Target Neighborhood Hits	245	Shared Neighborhood Hits	125
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

TMPS6_HUMAN
NC score	0.084894 (rank : 500)	θ value	0.813845 (rank : 283)
Query Neighborhood Hits	349	Target Neighborhood Hits	338	Shared Neighborhood Hits	112
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TNR9_HUMAN
NC score	0.084555 (rank : 501)	θ value	θ > 10 (rank : 651)
Query Neighborhood Hits	349	Target Neighborhood Hits	166	Shared Neighborhood Hits	55
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

CO9_HUMAN
NC score	0.083909 (rank : 502)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	349	Target Neighborhood Hits	147	Shared Neighborhood Hits	66
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

TSG6_HUMAN
NC score	0.083808 (rank : 503)	θ value	θ > 10 (rank : 654)
Query Neighborhood Hits	349	Target Neighborhood Hits	91	Shared Neighborhood Hits	33
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
NC score	0.083461 (rank : 504)	θ value	θ > 10 (rank : 655)
Query Neighborhood Hits	349	Target Neighborhood Hits	91	Shared Neighborhood Hits	32
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

TMPS6_MOUSE
NC score	0.083431 (rank : 505)	θ value	1.06291 (rank : 290)
Query Neighborhood Hits	349	Target Neighborhood Hits	341	Shared Neighborhood Hits	114
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

ADA19_MOUSE
NC score	0.082232 (rank : 506)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	349	Target Neighborhood Hits	315	Shared Neighborhood Hits	123
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ADA10_MOUSE
NC score	0.082000 (rank : 507)	θ value	0.813845 (rank : 281)
Query Neighborhood Hits	349	Target Neighborhood Hits	194	Shared Neighborhood Hits	68
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

FST_MOUSE
NC score	0.081085 (rank : 508)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	349	Target Neighborhood Hits	146	Shared Neighborhood Hits	56
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

LCE2C_HUMAN
NC score	0.081070 (rank : 509)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	349	Target Neighborhood Hits	53	Shared Neighborhood Hits	20
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

ADA19_HUMAN
NC score	0.080857 (rank : 510)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	349	Target Neighborhood Hits	381	Shared Neighborhood Hits	116
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

MFRP_HUMAN
NC score	0.080513 (rank : 511)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	349	Target Neighborhood Hits	165	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

ADA15_MOUSE
NC score	0.079842 (rank : 512)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	349	Target Neighborhood Hits	324	Shared Neighborhood Hits	128
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

MKS3_MOUSE
NC score	0.079190 (rank : 513)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	349	Target Neighborhood Hits	89	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

RSPO3_MOUSE
NC score	0.079181 (rank : 514)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	349	Target Neighborhood Hits	120	Shared Neighborhood Hits	48
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

LCE3B_HUMAN
NC score	0.079097 (rank : 515)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	349	Target Neighborhood Hits	47	Shared Neighborhood Hits	26
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

ADAM8_HUMAN
NC score	0.077762 (rank : 516)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	349	Target Neighborhood Hits	327	Shared Neighborhood Hits	119
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ADA18_MOUSE
NC score	0.077512 (rank : 517)	θ value	0.00175202 (rank : 215)
Query Neighborhood Hits	349	Target Neighborhood Hits	227	Shared Neighborhood Hits	90
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

EPGN_MOUSE
NC score	0.076966 (rank : 518)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	349	Target Neighborhood Hits	63	Shared Neighborhood Hits	40
SwissProt Accessions	Q924X1, Q8CEX5	Gene names	Epgn
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

MT4_MOUSE
NC score	0.076417 (rank : 519)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	349	Target Neighborhood Hits	102	Shared Neighborhood Hits	51
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

ADA17_HUMAN
NC score	0.076354 (rank : 520)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	349	Target Neighborhood Hits	223	Shared Neighborhood Hits	89
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

SHBG_MOUSE
NC score	0.074118 (rank : 521)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	349	Target Neighborhood Hits	50	Shared Neighborhood Hits	24
SwissProt Accessions	P97497	Gene names	Shbg
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP).

MFRP_MOUSE
NC score	0.073269 (rank : 522)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	349	Target Neighborhood Hits	166	Shared Neighborhood Hits	48
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

SEM5A_HUMAN
NC score	0.073239 (rank : 523)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	349	Target Neighborhood Hits	177	Shared Neighborhood Hits	44
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

BTC_MOUSE
NC score	0.073068 (rank : 524)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	349	Target Neighborhood Hits	67	Shared Neighborhood Hits	39
SwissProt Accessions	Q05928	Gene names	Btc, Bcn
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

TNR16_MOUSE
NC score	0.072619 (rank : 525)	θ value	θ > 10 (rank : 646)
Query Neighborhood Hits	349	Target Neighborhood Hits	178	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

CSMD3_HUMAN
NC score	0.071738 (rank : 526)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	349	Target Neighborhood Hits	199	Shared Neighborhood Hits	67
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

MYOC_MOUSE
NC score	0.070162 (rank : 527)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	349	Target Neighborhood Hits	232	Shared Neighborhood Hits	3
SwissProt Accessions	O70624, O70289	Gene names	Myoc, Tigr
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

ADAM9_MOUSE
NC score	0.069891 (rank : 528)	θ value	5.27518 (rank : 321)
Query Neighborhood Hits	349	Target Neighborhood Hits	325	Shared Neighborhood Hits	111
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

FST_HUMAN
NC score	0.069468 (rank : 529)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	349	Target Neighborhood Hits	129	Shared Neighborhood Hits	44
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

TNR11_HUMAN
NC score	0.069432 (rank : 530)	θ value	θ > 10 (rank : 642)
Query Neighborhood Hits	349	Target Neighborhood Hits	135	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR16_HUMAN
NC score	0.069206 (rank : 531)	θ value	θ > 10 (rank : 645)
Query Neighborhood Hits	349	Target Neighborhood Hits	183	Shared Neighborhood Hits	60
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

ADAM7_HUMAN
NC score	0.069148 (rank : 532)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	349	Target Neighborhood Hits	221	Shared Neighborhood Hits	103
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

OLFL1_HUMAN
NC score	0.069061 (rank : 533)	θ value	θ > 10 (rank : 579)
Query Neighborhood Hits	349	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q6UWY5	Gene names	OLFML1
Domain Architecture	No domain graphic available
Description	Olfactomedin-like protein 1 precursor.

SEM5B_MOUSE
NC score	0.069036 (rank : 534)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	349	Target Neighborhood Hits	190	Shared Neighborhood Hits	40
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

CUZD1_HUMAN
NC score	0.069004 (rank : 535)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	349	Target Neighborhood Hits	89	Shared Neighborhood Hits	32
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

SHBG_HUMAN
NC score	0.068869 (rank : 536)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	349	Target Neighborhood Hits	45	Shared Neighborhood Hits	20
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

CSMD1_MOUSE
NC score	0.068599 (rank : 537)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	349	Target Neighborhood Hits	193	Shared Neighborhood Hits	62
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD1_HUMAN
NC score	0.068274 (rank : 538)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	349	Target Neighborhood Hits	176	Shared Neighborhood Hits	54
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

LCE2D_HUMAN
NC score	0.068233 (rank : 539)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	349	Target Neighborhood Hits	50	Shared Neighborhood Hits	17
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

LCE2B_HUMAN
NC score	0.068226 (rank : 540)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	349	Target Neighborhood Hits	50	Shared Neighborhood Hits	21
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

ADA33_HUMAN
NC score	0.068014 (rank : 541)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	349	Target Neighborhood Hits	264	Shared Neighborhood Hits	103
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA30_HUMAN
NC score	0.067926 (rank : 542)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	349	Target Neighborhood Hits	391	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ADA18_HUMAN
NC score	0.067755 (rank : 543)	θ value	1.06291 (rank : 286)
Query Neighborhood Hits	349	Target Neighborhood Hits	184	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

UNC5A_MOUSE
NC score	0.067572 (rank : 544)	θ value	θ > 10 (rank : 656)
Query Neighborhood Hits	349	Target Neighborhood Hits	203	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

MCSP_MOUSE
NC score	0.066958 (rank : 545)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	349	Target Neighborhood Hits	108	Shared Neighborhood Hits	33
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

SEM5B_HUMAN
NC score	0.066806 (rank : 546)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	349	Target Neighborhood Hits	178	Shared Neighborhood Hits	31
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

ADA15_HUMAN
NC score	0.066195 (rank : 547)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	349	Target Neighborhood Hits	288	Shared Neighborhood Hits	113
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

NOE2_HUMAN
NC score	0.066072 (rank : 548)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	349	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	O95897, Q6IMJ3, Q96FC2	Gene names	OLFM2, NOE2
Domain Architecture
Description	Noelin-2 precursor (Olfactomedin-2).

NOE2_MOUSE
NC score	0.066033 (rank : 549)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	349	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BM13	Gene names	Olfm2
Domain Architecture	No domain graphic available
Description	Noelin-2 precursor (Olfactomedin-2).

NETO2_MOUSE
NC score	0.065850 (rank : 550)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	349	Target Neighborhood Hits	113	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

ADA12_HUMAN
NC score	0.065725 (rank : 551)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	349	Target Neighborhood Hits	224	Shared Neighborhood Hits	98
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA21_MOUSE
NC score	0.065620 (rank : 552)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	349	Target Neighborhood Hits	172	Shared Neighborhood Hits	85
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

CUZD1_MOUSE
NC score	0.065533 (rank : 553)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	349	Target Neighborhood Hits	91	Shared Neighborhood Hits	30
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

PAPPA_MOUSE
NC score	0.065500 (rank : 554)	θ value	θ > 10 (rank : 583)
Query Neighborhood Hits	349	Target Neighborhood Hits	153	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

OLFL3_HUMAN
NC score	0.065408 (rank : 555)	θ value	θ > 10 (rank : 580)
Query Neighborhood Hits	349	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NRN5, Q53FR1, Q53HV9, Q5SQL6, Q69AX9, Q8NBJ2	Gene names	OLFML3
Domain Architecture
Description	Olfactomedin-like protein 3 precursor (HNOEL-iso) (hOLF44).

NETO1_HUMAN
NC score	0.065395 (rank : 556)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	349	Target Neighborhood Hits	110	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO2_HUMAN
NC score	0.065342 (rank : 557)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	349	Target Neighborhood Hits	109	Shared Neighborhood Hits	43
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

OLFL3_MOUSE
NC score	0.065314 (rank : 558)	θ value	θ > 10 (rank : 581)
Query Neighborhood Hits	349	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BK62, Q3V2F2, Q8C1T0, Q99K37	Gene names	Olfml3
Domain Architecture	No domain graphic available
Description	Olfactomedin-like protein 3 precursor.

ADM1A_MOUSE
NC score	0.065146 (rank : 559)	θ value	0.163984 (rank : 253)
Query Neighborhood Hits	349	Target Neighborhood Hits	230	Shared Neighborhood Hits	100
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

NETO1_MOUSE
NC score	0.064863 (rank : 560)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	349	Target Neighborhood Hits	109	Shared Neighborhood Hits	44
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

CSMD2_HUMAN
NC score	0.064768 (rank : 561)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	349	Target Neighborhood Hits	188	Shared Neighborhood Hits	55
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

DKK3_MOUSE
NC score	0.064648 (rank : 562)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	349	Target Neighborhood Hits	83	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

UNC5B_MOUSE
NC score	0.064409 (rank : 563)	θ value	θ > 10 (rank : 658)
Query Neighborhood Hits	349	Target Neighborhood Hits	226	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

EPGN_HUMAN
NC score	0.064085 (rank : 564)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	349	Target Neighborhood Hits	59	Shared Neighborhood Hits	37
SwissProt Accessions	Q6UW88	Gene names	EPGN
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

UNC5B_HUMAN
NC score	0.064028 (rank : 565)	θ value	θ > 10 (rank : 657)
Query Neighborhood Hits	349	Target Neighborhood Hits	225	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

NOE3_HUMAN
NC score	0.064020 (rank : 566)	θ value	θ > 10 (rank : 560)
Query Neighborhood Hits	349	Target Neighborhood Hits	109	Shared Neighborhood Hits	3
SwissProt Accessions	Q96PB7, Q8TBG1, Q96PB2, Q96PB3, Q96PB4, Q96PB5, Q96PB6	Gene names	OLFM3, NOE3
Domain Architecture
Description	Noelin-3 precursor (Olfactomedin-3) (Optimedin).

NOE3_MOUSE
NC score	0.063875 (rank : 567)	θ value	θ > 10 (rank : 561)
Query Neighborhood Hits	349	Target Neighborhood Hits	116	Shared Neighborhood Hits	3
SwissProt Accessions	P63056, Q8BKV2, Q8BLL6, Q8QZW0, Q8R4K3, Q8R4K4	Gene names	Olfm3, Noe3
Domain Architecture	No domain graphic available
Description	Noelin-3 precursor (Olfactomedin-3) (Optimedin).

PCOC1_MOUSE
NC score	0.063397 (rank : 568)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	349	Target Neighborhood Hits	100	Shared Neighborhood Hits	27
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC1_HUMAN
NC score	0.062867 (rank : 569)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	349	Target Neighborhood Hits	146	Shared Neighborhood Hits	27
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

ESM1_MOUSE
NC score	0.062426 (rank : 570)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	349	Target Neighborhood Hits	107	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

PAPPA_HUMAN
NC score	0.062301 (rank : 571)	θ value	θ > 10 (rank : 582)
Query Neighborhood Hits	349	Target Neighborhood Hits	161	Shared Neighborhood Hits	58
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

ADAM2_HUMAN
NC score	0.062294 (rank : 572)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	349	Target Neighborhood Hits	175	Shared Neighborhood Hits	78
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

ATL2_HUMAN
NC score	0.062160 (rank : 573)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	349	Target Neighborhood Hits	125	Shared Neighborhood Hits	32
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

MEP1B_HUMAN
NC score	0.062103 (rank : 574)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	349	Target Neighborhood Hits	98	Shared Neighborhood Hits	53
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

SEM5A_MOUSE
NC score	0.062031 (rank : 575)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	349	Target Neighborhood Hits	162	Shared Neighborhood Hits	25
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

UNC5C_HUMAN
NC score	0.062015 (rank : 576)	θ value	θ > 10 (rank : 659)
Query Neighborhood Hits	349	Target Neighborhood Hits	226	Shared Neighborhood Hits	15
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

ADA33_MOUSE
NC score	0.061814 (rank : 577)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	349	Target Neighborhood Hits	231	Shared Neighborhood Hits	88
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

NOE1_MOUSE
NC score	0.061715 (rank : 578)	θ value	θ > 10 (rank : 557)
Query Neighborhood Hits	349	Target Neighborhood Hits	258	Shared Neighborhood Hits	4
SwissProt Accessions	O88998, O35429, O88999, Q91XK8, Q9QWQ9, Q9QWR0	Gene names	Olfm1, Noe1, Noel, Noel1
Domain Architecture
Description	Noelin precursor (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1) (Pancortin).

UNC5C_MOUSE
NC score	0.061700 (rank : 579)	θ value	θ > 10 (rank : 660)
Query Neighborhood Hits	349	Target Neighborhood Hits	225	Shared Neighborhood Hits	14
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

PCOC2_HUMAN
NC score	0.061676 (rank : 580)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	349	Target Neighborhood Hits	73	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

CYR61_HUMAN
NC score	0.061437 (rank : 581)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	349	Target Neighborhood Hits	159	Shared Neighborhood Hits	59
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

NOE1_HUMAN
NC score	0.061027 (rank : 582)	θ value	θ > 10 (rank : 556)
Query Neighborhood Hits	349	Target Neighborhood Hits	266	Shared Neighborhood Hits	4
SwissProt Accessions	Q99784, Q969S7, Q99452	Gene names	OLFM1, NOE1, NOEL1
Domain Architecture
Description	Noelin precursor (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1).

EREG_MOUSE
NC score	0.060895 (rank : 583)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	349	Target Neighborhood Hits	65	Shared Neighborhood Hits	37
SwissProt Accessions	Q61521, Q7M0A8	Gene names	Ereg
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

PCOC2_MOUSE
NC score	0.060584 (rank : 584)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	349	Target Neighborhood Hits	73	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

UNC5D_MOUSE
NC score	0.059924 (rank : 585)	θ value	θ > 10 (rank : 662)
Query Neighborhood Hits	349	Target Neighborhood Hits	268	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

TMG1_HUMAN
NC score	0.059895 (rank : 586)	θ value	θ > 10 (rank : 639)
Query Neighborhood Hits	349	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	O14668	Gene names	PRRG1, PRGP1, TMG1
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 1 precursor (Proline- rich Gla protein 1) (Proline-rich gamma-carboxyglutamic acid protein 1).

UNC5D_HUMAN
NC score	0.059819 (rank : 587)	θ value	θ > 10 (rank : 661)
Query Neighborhood Hits	349	Target Neighborhood Hits	267	Shared Neighborhood Hits	21
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

BTC_HUMAN
NC score	0.059579 (rank : 588)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	349	Target Neighborhood Hits	70	Shared Neighborhood Hits	38
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

ATL2_MOUSE
NC score	0.059260 (rank : 589)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	349	Target Neighborhood Hits	137	Shared Neighborhood Hits	31
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

CYR61_MOUSE
NC score	0.059226 (rank : 590)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	349	Target Neighborhood Hits	156	Shared Neighborhood Hits	56
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

PCD15_HUMAN
NC score	0.058997 (rank : 591)	θ value	θ > 10 (rank : 584)
Query Neighborhood Hits	349	Target Neighborhood Hits	289	Shared Neighborhood Hits	13
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

CAD23_MOUSE
NC score	0.058974 (rank : 592)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	349	Target Neighborhood Hits	208	Shared Neighborhood Hits	11
SwissProt Accessions	Q99PF4, Q99NH1, Q9D4N9	Gene names	Cdh23
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

MT3_HUMAN
NC score	0.058959 (rank : 593)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	349	Target Neighborhood Hits	82	Shared Neighborhood Hits	37
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

MYOC_HUMAN
NC score	0.058923 (rank : 594)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	349	Target Neighborhood Hits	489	Shared Neighborhood Hits	3
SwissProt Accessions	Q99972, O00620, Q7Z6Q9	Gene names	MYOC, GLC1A, TIGR
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

CAD23_HUMAN
NC score	0.058825 (rank : 595)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	349	Target Neighborhood Hits	197	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H251, Q6UWW1, Q9H4K9	Gene names	CDH23, KIAA1774
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

ADAM2_MOUSE
NC score	0.058663 (rank : 596)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	349	Target Neighborhood Hits	209	Shared Neighborhood Hits	89
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

MT3_MOUSE
NC score	0.058348 (rank : 597)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	349	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

ADM1B_MOUSE
NC score	0.058264 (rank : 598)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	349	Target Neighborhood Hits	236	Shared Neighborhood Hits	91
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

ADAM9_HUMAN
NC score	0.057944 (rank : 599)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	349	Target Neighborhood Hits	243	Shared Neighborhood Hits	97
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

PCD15_MOUSE
NC score	0.057932 (rank : 600)	θ value	θ > 10 (rank : 585)
Query Neighborhood Hits	349	Target Neighborhood Hits	262	Shared Neighborhood Hits	11
SwissProt Accessions	Q99PJ1	Gene names	Pcdh15
Domain Architecture
Description	Protocadherin-15 precursor.

TGFA_HUMAN
NC score	0.057674 (rank : 601)	θ value	θ > 10 (rank : 633)
Query Neighborhood Hits	349	Target Neighborhood Hits	61	Shared Neighborhood Hits	40
SwissProt Accessions	P01135, Q15577	Gene names	TGFA
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

SEZ6L_HUMAN
NC score	0.057616 (rank : 602)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	349	Target Neighborhood Hits	289	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

ADA21_HUMAN
NC score	0.057476 (rank : 603)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	349	Target Neighborhood Hits	181	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

PDGFD_HUMAN
NC score	0.057108 (rank : 604)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	349	Target Neighborhood Hits	74	Shared Neighborhood Hits	26
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

NRP2_HUMAN
NC score	0.056983 (rank : 605)	θ value	θ > 10 (rank : 569)
Query Neighborhood Hits	349	Target Neighborhood Hits	120	Shared Neighborhood Hits	35
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

PDGFD_MOUSE
NC score	0.056945 (rank : 606)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	349	Target Neighborhood Hits	72	Shared Neighborhood Hits	26
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

GP2_HUMAN
NC score	0.056882 (rank : 607)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	349	Target Neighborhood Hits	34	Shared Neighborhood Hits	12
SwissProt Accessions	P55259, Q13338, Q9UIF1	Gene names	GP2
Domain Architecture
Description	Pancreatic secretory granule membrane major glycoprotein GP2 precursor (Pancreatic zymogen granule membrane protein GP-2) (ZAP75).

DMBT1_MOUSE
NC score	0.056678 (rank : 608)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	349	Target Neighborhood Hits	134	Shared Neighborhood Hits	33
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

PCD16_HUMAN
NC score	0.056619 (rank : 609)	θ value	θ > 10 (rank : 586)
Query Neighborhood Hits	349	Target Neighborhood Hits	245	Shared Neighborhood Hits	13
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

HBEGF_HUMAN
NC score	0.056323 (rank : 610)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	349	Target Neighborhood Hits	61	Shared Neighborhood Hits	40
SwissProt Accessions	Q99075	Gene names	HBEGF, DTR, HEGFL
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF) (Diphtheria toxin receptor) (DT-R).

DKK3_HUMAN
NC score	0.056000 (rank : 611)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	349	Target Neighborhood Hits	74	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UBP4, Q9ULB7	Gene names	DKK3, REIC
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3).

WISP2_HUMAN
NC score	0.055981 (rank : 612)	θ value	θ > 10 (rank : 672)
Query Neighborhood Hits	349	Target Neighborhood Hits	126	Shared Neighborhood Hits	40
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

LCE2A_HUMAN
NC score	0.055951 (rank : 613)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	349	Target Neighborhood Hits	50	Shared Neighborhood Hits	20
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

THSD1_MOUSE
NC score	0.055721 (rank : 614)	θ value	θ > 10 (rank : 635)
Query Neighborhood Hits	349	Target Neighborhood Hits	153	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

ADA28_HUMAN
NC score	0.055652 (rank : 615)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	349	Target Neighborhood Hits	244	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

TNR8_MOUSE
NC score	0.055601 (rank : 616)	θ value	θ > 10 (rank : 650)
Query Neighborhood Hits	349	Target Neighborhood Hits	208	Shared Neighborhood Hits	50
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

CU063_HUMAN
NC score	0.055523 (rank : 617)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	349	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	P58658, Q8IXZ0	Gene names	C21orf63
Domain Architecture
Description	Protein C21orf63 precursor (SUE21).

MT4_HUMAN
NC score	0.055492 (rank : 618)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	349	Target Neighborhood Hits	83	Shared Neighborhood Hits	38
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

NRP2_MOUSE
NC score	0.055389 (rank : 619)	θ value	θ > 10 (rank : 570)
Query Neighborhood Hits	349	Target Neighborhood Hits	113	Shared Neighborhood Hits	33
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

PCDLK_HUMAN
NC score	0.055378 (rank : 620)	θ value	θ > 10 (rank : 587)
Query Neighborhood Hits	349	Target Neighborhood Hits	172	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BYE9, Q9NXP8	Gene names	PCLKC
Domain Architecture	No domain graphic available
Description	Protocadherin LKC precursor (PC-LKC).

CRDL2_MOUSE
NC score	0.054964 (rank : 621)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	349	Target Neighborhood Hits	81	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

CU063_MOUSE
NC score	0.054301 (rank : 622)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	349	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	P58659	Gene names
Domain Architecture
Description	Protein C21orf63 homolog precursor.

ADA17_MOUSE
NC score	0.054193 (rank : 623)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	349	Target Neighborhood Hits	201	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

GNPTA_HUMAN
NC score	0.054132 (rank : 624)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	349	Target Neighborhood Hits	43	Shared Neighborhood Hits	9
SwissProt Accessions	Q3T906, Q3ZQK2, Q6IPW5, Q86TQ2, Q96N13, Q9ULL2	Gene names	GNPTAB, GNPTA, KIAA1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

TMG3_HUMAN
NC score	0.054065 (rank : 625)	θ value	θ > 10 (rank : 640)
Query Neighborhood Hits	349	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BZD7, Q8N2N6	Gene names	PRRG3, TMG3
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 3 precursor (Proline- rich Gla protein 3) (Proline-rich gamma-carboxyglutamic acid protein 3).

THSD1_HUMAN
NC score	0.053886 (rank : 626)	θ value	θ > 10 (rank : 634)
Query Neighborhood Hits	349	Target Neighborhood Hits	136	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

ADA32_HUMAN
NC score	0.053505 (rank : 627)	θ value	4.03905 (rank : 315)
Query Neighborhood Hits	349	Target Neighborhood Hits	216	Shared Neighborhood Hits	99
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

TNR7_HUMAN
NC score	0.053387 (rank : 628)	θ value	θ > 10 (rank : 648)
Query Neighborhood Hits	349	Target Neighborhood Hits	120	Shared Neighborhood Hits	50
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

DCBD1_MOUSE
NC score	0.053359 (rank : 629)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	349	Target Neighborhood Hits	89	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

TNR14_HUMAN
NC score	0.053239 (rank : 630)	θ value	θ > 10 (rank : 644)
Query Neighborhood Hits	349	Target Neighborhood Hits	149	Shared Neighborhood Hits	53
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TMG3_MOUSE
NC score	0.053131 (rank : 631)	θ value	θ > 10 (rank : 641)
Query Neighborhood Hits	349	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PAQ9	Gene names	Prrg3, Gm368, Tmg3
Domain Architecture	No domain graphic available
Description	Transmembrane gamma-carboxyglutamic acid protein 3 precursor (Proline- rich Gla protein 3) (Proline-rich gamma-carboxyglutamic acid protein 3).

ADA22_MOUSE
NC score	0.052970 (rank : 632)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	349	Target Neighborhood Hits	225	Shared Neighborhood Hits	82
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

GNPTA_MOUSE
NC score	0.052848 (rank : 633)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	349	Target Neighborhood Hits	47	Shared Neighborhood Hits	9
SwissProt Accessions	Q69ZN6, Q3U3K6, Q3US34	Gene names	Gnptab, Gnpta, Kiaa1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

IDD_HUMAN
NC score	0.052218 (rank : 634)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	349	Target Neighborhood Hits	127	Shared Neighborhood Hits	36
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

TNR8_HUMAN
NC score	0.052204 (rank : 635)	θ value	θ > 10 (rank : 649)
Query Neighborhood Hits	349	Target Neighborhood Hits	198	Shared Neighborhood Hits	53
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

RSPO4_HUMAN
NC score	0.052183 (rank : 636)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	349	Target Neighborhood Hits	110	Shared Neighborhood Hits	49
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

NRP1_MOUSE
NC score	0.051713 (rank : 637)	θ value	θ > 10 (rank : 568)
Query Neighborhood Hits	349	Target Neighborhood Hits	120	Shared Neighborhood Hits	34
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

GP2_MOUSE
NC score	0.051675 (rank : 638)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	349	Target Neighborhood Hits	29	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D733	Gene names	Gp2
Domain Architecture	No domain graphic available
Description	Pancreatic secretory granule membrane major glycoprotein GP2 precursor (Pancreatic zymogen granule membrane protein GP-2).

TNR11_MOUSE
NC score	0.051619 (rank : 639)	θ value	θ > 10 (rank : 643)
Query Neighborhood Hits	349	Target Neighborhood Hits	121	Shared Neighborhood Hits	45
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

CTGF_HUMAN
NC score	0.051540 (rank : 640)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	349	Target Neighborhood Hits	128	Shared Neighborhood Hits	45
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

NRP1_HUMAN
NC score	0.051463 (rank : 641)	θ value	θ > 10 (rank : 567)
Query Neighborhood Hits	349	Target Neighborhood Hits	119	Shared Neighborhood Hits	35
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

ATS9_HUMAN
NC score	0.051438 (rank : 642)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	349	Target Neighborhood Hits	219	Shared Neighborhood Hits	57
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

ATS20_MOUSE
NC score	0.051160 (rank : 643)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	349	Target Neighborhood Hits	225	Shared Neighborhood Hits	51
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

CILP2_HUMAN
NC score	0.051099 (rank : 644)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	349	Target Neighborhood Hits	307	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

CAD17_MOUSE
NC score	0.050577 (rank : 645)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	349	Target Neighborhood Hits	157	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R100	Gene names	Cdh17
Domain Architecture
Description	Cadherin-17 precursor (Liver-intestine-cadherin) (LI-cadherin) (BILL- cadherin) (P130).

ADAM7_MOUSE
NC score	0.050504 (rank : 646)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	349	Target Neighborhood Hits	200	Shared Neighborhood Hits	90
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADA28_MOUSE
NC score	0.050280 (rank : 647)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	349	Target Neighborhood Hits	241	Shared Neighborhood Hits	95
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

TNR1A_HUMAN
NC score	0.044153 (rank : 648)	θ value	0.813845 (rank : 284)
Query Neighborhood Hits	349	Target Neighborhood Hits	121	Shared Neighborhood Hits	32
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

ENTK_MOUSE
NC score	0.043667 (rank : 649)	θ value	1.81305 (rank : 303)
Query Neighborhood Hits	349	Target Neighborhood Hits	338	Shared Neighborhood Hits	66
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

FZD3_HUMAN
NC score	0.042179 (rank : 650)	θ value	0.279714 (rank : 260)
Query Neighborhood Hits	349	Target Neighborhood Hits	74	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NPG1	Gene names	FZD3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (hFz3).

FZD3_MOUSE
NC score	0.041542 (rank : 651)	θ value	0.365318 (rank : 263)
Query Neighborhood Hits	349	Target Neighborhood Hits	75	Shared Neighborhood Hits	22
SwissProt Accessions	Q61086	Gene names	Fzd3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (mFz3).

ATS12_MOUSE
NC score	0.037008 (rank : 652)	θ value	2.36792 (rank : 307)
Query Neighborhood Hits	349	Target Neighborhood Hits	220	Shared Neighborhood Hits	30
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

GP143_HUMAN
NC score	0.035884 (rank : 653)	θ value	4.03905 (rank : 316)
Query Neighborhood Hits	349	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	P51810	Gene names	GPR143, OA1
Domain Architecture
Description	G-protein coupled receptor 143 (Ocular albinism type 1 protein).

TNR6_HUMAN
NC score	0.035486 (rank : 654)	θ value	6.88961 (rank : 337)
Query Neighborhood Hits	349	Target Neighborhood Hits	95	Shared Neighborhood Hits	37
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

GP143_MOUSE
NC score	0.030264 (rank : 655)	θ value	0.62314 (rank : 278)
Query Neighborhood Hits	349	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	P70259, O89031	Gene names	Gpr143, Oa1
Domain Architecture
Description	G-protein coupled receptor 143 (Ocular albinism type 1 protein homolog) (MOA1).

GP158_MOUSE
NC score	0.028959 (rank : 656)	θ value	1.38821 (rank : 293)
Query Neighborhood Hits	349	Target Neighborhood Hits	82	Shared Neighborhood Hits	18
SwissProt Accessions	Q8C419, Q8CHB0	Gene names	Gpr158, Kiaa1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

EPHB4_HUMAN
NC score	0.018052 (rank : 657)	θ value	8.99809 (rank : 345)
Query Neighborhood Hits	349	Target Neighborhood Hits	1056	Shared Neighborhood Hits	103
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

YIPF1_HUMAN
NC score	0.009265 (rank : 658)	θ value	1.81305 (rank : 306)
Query Neighborhood Hits	349	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y548, Q9NWJ1	Gene names	YIPF1
Domain Architecture	No domain graphic available
Description	Protein YIPF1 (YIP1 family member 1).

RAI3_MOUSE
NC score	0.008296 (rank : 659)	θ value	1.38821 (rank : 302)
Query Neighborhood Hits	349	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHL4, Q8K067, Q8K1G5	Gene names	Gprc5a, Rai3, Raig1
Domain Architecture
Description	Retinoic acid-induced protein 3 (G-protein coupled receptor family C group 5 member A) (Retinoic acid-induced gene 1 protein) (RAIG-1).

ATRAP_HUMAN
NC score	0.006085 (rank : 660)	θ value	6.88961 (rank : 330)
Query Neighborhood Hits	349	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q6RW13, Q5SNV4, Q5SNV5, Q96AC0, Q96PL4, Q9NRW9	Gene names	AGTRAP, ATRAP
Domain Architecture	No domain graphic available
Description	Type-1 angiotensin II receptor-associated protein (AT1 receptor- associated protein).

HTRA4_HUMAN
NC score	0.005034 (rank : 661)	θ value	6.88961 (rank : 333)
Query Neighborhood Hits	349	Target Neighborhood Hits	119	Shared Neighborhood Hits	9
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

RTN4_HUMAN
NC score	0.003375 (rank : 662)	θ value	4.03905 (rank : 320)
Query Neighborhood Hits	349	Target Neighborhood Hits	357	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

CKLF6_HUMAN
NC score	0.003286 (rank : 663)	θ value	8.99809 (rank : 342)
Query Neighborhood Hits	349	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NX76	Gene names	CMTM6, CKLFSF6
Domain Architecture
Description	CKLF-like MARVEL transmembrane domain-containing protein 6 (Chemokine- like factor superfamily member 6).

ARP5_HUMAN
NC score	0.002952 (rank : 664)	θ value	3.0926 (rank : 312)
Query Neighborhood Hits	349	Target Neighborhood Hits	107	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H9F9, Q86WF7, Q8IUY5, Q8N724, Q9BRN0, Q9BVB7	Gene names	ACTR5, ARP5
Domain Architecture	No domain graphic available
Description	Actin-related protein 5 (hARP5) (Sarcoma antigen NY-SAR-16).

NPCL1_HUMAN
NC score	0.002069 (rank : 665)	θ value	6.88961 (rank : 336)
Query Neighborhood Hits	349	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UHC9, Q6R3Q4, Q9UHC8	Gene names	NPC1L1
Domain Architecture	No domain graphic available
Description	Niemann-Pick C1-like protein 1 precursor.

ARP5_MOUSE
NC score	0.001607 (rank : 666)	θ value	8.99809 (rank : 338)
Query Neighborhood Hits	349	Target Neighborhood Hits	116	Shared Neighborhood Hits	3
SwissProt Accessions	Q80US4, Q8BL26	Gene names	Actr5
Domain Architecture	No domain graphic available
Description	Actin-related protein 5.

CHSS1_HUMAN
NC score	0.001540 (rank : 667)	θ value	8.99809 (rank : 340)
Query Neighborhood Hits	349	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q86X52, Q6UX38, Q7LFU5, Q9Y2J5	Gene names	CHSY1, CHSY, CSS1, KIAA0990
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 1 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase 1) (Chondroitin sulfate synthase 1) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II).

CHSS1_MOUSE
NC score	0.001539 (rank : 668)	θ value	8.99809 (rank : 341)
Query Neighborhood Hits	349	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZQ11	Gene names	Chsy1, Kiaa0990
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 1 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase) (Chondroitin sulfate synthase 1) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II).

WNT8A_HUMAN
NC score	0.001208 (rank : 669)	θ value	0.813845 (rank : 285)
Query Neighborhood Hits	349	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H1J5, Q96S51	Gene names	WNT8A, WNT8D
Domain Architecture
Description	Protein Wnt-8a precursor (Wnt-8d).

NALP4_HUMAN
NC score	0.000938 (rank : 670)	θ value	2.36792 (rank : 309)
Query Neighborhood Hits	349	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	Q96MN2, Q86W87, Q96AY6	Gene names	NALP4, PAN2, PYPAF4, RNH2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 4 (PYRIN-containing APAF1-like protein 4) (PAAD and NACHT-containing protein 2) (PYRIN and NACHT- containing protein 2) (Ribonuclease inhibitor 2).

BIRC6_HUMAN
NC score	0.000772 (rank : 671)	θ value	8.99809 (rank : 339)
Query Neighborhood Hits	349	Target Neighborhood Hits	161	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).

GP141_HUMAN
NC score	-0.001934 (rank : 672)	θ value	1.06291 (rank : 288)
Query Neighborhood Hits	349	Target Neighborhood Hits	301	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z602, Q86SP3	Gene names	GPR141, PGR13
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 141 (G-protein coupled receptor PGR13).