Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : PROP_MOUSE

For an explanation of this page, click here

PROP_MOUSE
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PROP_HUMAN
θ value	0 (rank : 1)	NC score	0.985873 (rank : 2)
Query Neighborhood Hits	165	Target Neighborhood Hits	126	Shared Neighborhood Hits	95
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

PROP_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	165	Target Neighborhood Hits	165	Shared Neighborhood Hits	165
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

HMCN1_HUMAN
θ value	4.38363e-63 (rank : 3)	NC score	0.418548 (rank : 73)
Query Neighborhood Hits	165	Target Neighborhood Hits	983	Shared Neighborhood Hits	111
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

BAI3_HUMAN
θ value	7.25919e-50 (rank : 4)	NC score	0.725544 (rank : 6)
Query Neighborhood Hits	165	Target Neighborhood Hits	246	Shared Neighborhood Hits	90
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
θ value	2.1121e-49 (rank : 5)	NC score	0.728258 (rank : 5)
Query Neighborhood Hits	165	Target Neighborhood Hits	250	Shared Neighborhood Hits	90
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

SEM5B_MOUSE
θ value	7.51208e-47 (rank : 6)	NC score	0.627233 (rank : 42)
Query Neighborhood Hits	165	Target Neighborhood Hits	190	Shared Neighborhood Hits	93
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

BAI1_MOUSE
θ value	2.41655e-45 (rank : 7)	NC score	0.718006 (rank : 7)
Query Neighborhood Hits	165	Target Neighborhood Hits	340	Shared Neighborhood Hits	89
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

SEM5A_MOUSE
θ value	4.122e-45 (rank : 8)	NC score	0.623582 (rank : 46)
Query Neighborhood Hits	165	Target Neighborhood Hits	162	Shared Neighborhood Hits	84
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

BAI1_HUMAN
θ value	7.03111e-45 (rank : 9)	NC score	0.716772 (rank : 8)
Query Neighborhood Hits	165	Target Neighborhood Hits	375	Shared Neighborhood Hits	93
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

SEM5B_HUMAN
θ value	1.19932e-44 (rank : 10)	NC score	0.624601 (rank : 43)
Query Neighborhood Hits	165	Target Neighborhood Hits	178	Shared Neighborhood Hits	93
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

SEM5A_HUMAN
θ value	4.55743e-44 (rank : 11)	NC score	0.628253 (rank : 40)
Query Neighborhood Hits	165	Target Neighborhood Hits	177	Shared Neighborhood Hits	87
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

TSP1_MOUSE
θ value	4.2656e-42 (rank : 12)	NC score	0.676970 (rank : 20)
Query Neighborhood Hits	165	Target Neighborhood Hits	396	Shared Neighborhood Hits	107
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_HUMAN
θ value	1.2411e-41 (rank : 13)	NC score	0.676954 (rank : 21)
Query Neighborhood Hits	165	Target Neighborhood Hits	389	Shared Neighborhood Hits	109
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

BAI2_MOUSE
θ value	2.11701e-41 (rank : 14)	NC score	0.714118 (rank : 12)
Query Neighborhood Hits	165	Target Neighborhood Hits	323	Shared Neighborhood Hits	93
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_HUMAN
θ value	1.79215e-40 (rank : 15)	NC score	0.715344 (rank : 10)
Query Neighborhood Hits	165	Target Neighborhood Hits	332	Shared Neighborhood Hits	92
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

TSP2_HUMAN
θ value	1.51715e-39 (rank : 16)	NC score	0.687323 (rank : 18)
Query Neighborhood Hits	165	Target Neighborhood Hits	359	Shared Neighborhood Hits	109
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP2_MOUSE
θ value	1.6774e-38 (rank : 17)	NC score	0.690008 (rank : 16)
Query Neighborhood Hits	165	Target Neighborhood Hits	352	Shared Neighborhood Hits	106
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

SSPO_MOUSE
θ value	2.26708e-35 (rank : 18)	NC score	0.575057 (rank : 61)
Query Neighborhood Hits	165	Target Neighborhood Hits	800	Shared Neighborhood Hits	127
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

SPON1_MOUSE
θ value	1.99067e-23 (rank : 19)	NC score	0.805614 (rank : 3)
Query Neighborhood Hits	165	Target Neighborhood Hits	123	Shared Neighborhood Hits	91
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

SPON1_HUMAN
θ value	7.56453e-23 (rank : 20)	NC score	0.803740 (rank : 4)
Query Neighborhood Hits	165	Target Neighborhood Hits	117	Shared Neighborhood Hits	89
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

UNC5B_MOUSE
θ value	7.56453e-23 (rank : 21)	NC score	0.714746 (rank : 11)
Query Neighborhood Hits	165	Target Neighborhood Hits	226	Shared Neighborhood Hits	78
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5B_HUMAN
θ value	9.87957e-23 (rank : 22)	NC score	0.712429 (rank : 13)
Query Neighborhood Hits	165	Target Neighborhood Hits	225	Shared Neighborhood Hits	78
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5C_MOUSE
θ value	7.82807e-20 (rank : 23)	NC score	0.694799 (rank : 14)
Query Neighborhood Hits	165	Target Neighborhood Hits	225	Shared Neighborhood Hits	77
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

UNC5C_HUMAN
θ value	2.97466e-19 (rank : 24)	NC score	0.694777 (rank : 15)
Query Neighborhood Hits	165	Target Neighborhood Hits	226	Shared Neighborhood Hits	77
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5A_MOUSE
θ value	6.62687e-19 (rank : 25)	NC score	0.716177 (rank : 9)
Query Neighborhood Hits	165	Target Neighborhood Hits	203	Shared Neighborhood Hits	75
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5D_HUMAN
θ value	1.92812e-18 (rank : 26)	NC score	0.674283 (rank : 22)
Query Neighborhood Hits	165	Target Neighborhood Hits	267	Shared Neighborhood Hits	79
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5D_MOUSE
θ value	2.5182e-18 (rank : 27)	NC score	0.671507 (rank : 23)
Query Neighborhood Hits	165	Target Neighborhood Hits	268	Shared Neighborhood Hits	79
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

ATS9_HUMAN
θ value	1.24977e-17 (rank : 28)	NC score	0.659662 (rank : 24)
Query Neighborhood Hits	165	Target Neighborhood Hits	219	Shared Neighborhood Hits	96
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

ATS16_MOUSE
θ value	2.60593e-15 (rank : 29)	NC score	0.649574 (rank : 28)
Query Neighborhood Hits	165	Target Neighborhood Hits	179	Shared Neighborhood Hits	91
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS20_HUMAN
θ value	4.44505e-15 (rank : 30)	NC score	0.638147 (rank : 34)
Query Neighborhood Hits	165	Target Neighborhood Hits	192	Shared Neighborhood Hits	92
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS20_MOUSE
θ value	7.58209e-15 (rank : 31)	NC score	0.649002 (rank : 29)
Query Neighborhood Hits	165	Target Neighborhood Hits	225	Shared Neighborhood Hits	95
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATL3_HUMAN
θ value	2.20605e-14 (rank : 32)	NC score	0.581912 (rank : 60)
Query Neighborhood Hits	165	Target Neighborhood Hits	414	Shared Neighborhood Hits	88
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

ATS16_HUMAN
θ value	4.91457e-14 (rank : 33)	NC score	0.646919 (rank : 30)
Query Neighborhood Hits	165	Target Neighborhood Hits	208	Shared Neighborhood Hits	94
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS18_MOUSE
θ value	8.38298e-14 (rank : 34)	NC score	0.650907 (rank : 27)
Query Neighborhood Hits	165	Target Neighborhood Hits	163	Shared Neighborhood Hits	84
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS8_MOUSE
θ value	7.09661e-13 (rank : 35)	NC score	0.641476 (rank : 32)
Query Neighborhood Hits	165	Target Neighborhood Hits	139	Shared Neighborhood Hits	80
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

ATS18_HUMAN
θ value	3.52202e-12 (rank : 36)	NC score	0.642579 (rank : 31)
Query Neighborhood Hits	165	Target Neighborhood Hits	169	Shared Neighborhood Hits	86
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS4_HUMAN
θ value	3.52202e-12 (rank : 37)	NC score	0.636411 (rank : 35)
Query Neighborhood Hits	165	Target Neighborhood Hits	138	Shared Neighborhood Hits	77
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

ATS4_MOUSE
θ value	3.52202e-12 (rank : 38)	NC score	0.635819 (rank : 36)
Query Neighborhood Hits	165	Target Neighborhood Hits	145	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

ATS12_MOUSE
θ value	1.02475e-11 (rank : 39)	NC score	0.624374 (rank : 44)
Query Neighborhood Hits	165	Target Neighborhood Hits	220	Shared Neighborhood Hits	90
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS12_HUMAN
θ value	1.33837e-11 (rank : 40)	NC score	0.622381 (rank : 48)
Query Neighborhood Hits	165	Target Neighborhood Hits	251	Shared Neighborhood Hits	86
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS1_MOUSE
θ value	2.28291e-11 (rank : 41)	NC score	0.624172 (rank : 45)
Query Neighborhood Hits	165	Target Neighborhood Hits	158	Shared Neighborhood Hits	83
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

ATS6_HUMAN
θ value	2.98157e-11 (rank : 42)	NC score	0.618759 (rank : 51)
Query Neighborhood Hits	165	Target Neighborhood Hits	141	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

ATS8_HUMAN
θ value	2.98157e-11 (rank : 43)	NC score	0.633687 (rank : 37)
Query Neighborhood Hits	165	Target Neighborhood Hits	145	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

ATS2_HUMAN
θ value	1.133e-10 (rank : 44)	NC score	0.632383 (rank : 38)
Query Neighborhood Hits	165	Target Neighborhood Hits	179	Shared Neighborhood Hits	83
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS1_HUMAN
θ value	1.9326e-10 (rank : 45)	NC score	0.621709 (rank : 49)
Query Neighborhood Hits	165	Target Neighborhood Hits	159	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

ATS3_HUMAN
θ value	1.9326e-10 (rank : 46)	NC score	0.612944 (rank : 54)
Query Neighborhood Hits	165	Target Neighborhood Hits	179	Shared Neighborhood Hits	87
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS17_HUMAN
θ value	2.52405e-10 (rank : 47)	NC score	0.639190 (rank : 33)
Query Neighborhood Hits	165	Target Neighborhood Hits	194	Shared Neighborhood Hits	90
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

ATL2_MOUSE
θ value	5.62301e-10 (rank : 48)	NC score	0.688126 (rank : 17)
Query Neighborhood Hits	165	Target Neighborhood Hits	137	Shared Neighborhood Hits	83
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

ATS19_MOUSE
θ value	7.34386e-10 (rank : 49)	NC score	0.606558 (rank : 56)
Query Neighborhood Hits	165	Target Neighborhood Hits	188	Shared Neighborhood Hits	79
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

CILP2_HUMAN
θ value	9.59137e-10 (rank : 50)	NC score	0.507691 (rank : 69)
Query Neighborhood Hits	165	Target Neighborhood Hits	307	Shared Neighborhood Hits	82
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

ATL2_HUMAN
θ value	1.25267e-09 (rank : 51)	NC score	0.686591 (rank : 19)
Query Neighborhood Hits	165	Target Neighborhood Hits	125	Shared Neighborhood Hits	82
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

ATS15_HUMAN
θ value	1.63604e-09 (rank : 52)	NC score	0.617585 (rank : 53)
Query Neighborhood Hits	165	Target Neighborhood Hits	151	Shared Neighborhood Hits	82
SwissProt Accessions	Q8TE58	Gene names	ADAMTS15
Domain Architecture
Description	ADAMTS-15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 15) (ADAM-TS 15) (ADAM-TS15).

ATS5_MOUSE
θ value	4.76016e-09 (rank : 53)	NC score	0.602970 (rank : 57)
Query Neighborhood Hits	165	Target Neighborhood Hits	147	Shared Neighborhood Hits	79
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

ATS13_HUMAN
θ value	6.21693e-09 (rank : 54)	NC score	0.658576 (rank : 25)
Query Neighborhood Hits	165	Target Neighborhood Hits	238	Shared Neighborhood Hits	88
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS19_HUMAN
θ value	6.21693e-09 (rank : 55)	NC score	0.596937 (rank : 58)
Query Neighborhood Hits	165	Target Neighborhood Hits	203	Shared Neighborhood Hits	76
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS13_MOUSE
θ value	8.11959e-09 (rank : 56)	NC score	0.651956 (rank : 26)
Query Neighborhood Hits	165	Target Neighborhood Hits	227	Shared Neighborhood Hits	87
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS2_MOUSE
θ value	8.11959e-09 (rank : 57)	NC score	0.627335 (rank : 41)
Query Neighborhood Hits	165	Target Neighborhood Hits	179	Shared Neighborhood Hits	81
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS7_HUMAN
θ value	8.11959e-09 (rank : 58)	NC score	0.609361 (rank : 55)
Query Neighborhood Hits	165	Target Neighborhood Hits	169	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

ATS14_HUMAN
θ value	3.08544e-08 (rank : 59)	NC score	0.623255 (rank : 47)
Query Neighborhood Hits	165	Target Neighborhood Hits	382	Shared Neighborhood Hits	92
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

CO8B_MOUSE
θ value	3.08544e-08 (rank : 60)	NC score	0.538585 (rank : 65)
Query Neighborhood Hits	165	Target Neighborhood Hits	224	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

ATS5_HUMAN
θ value	4.0297e-08 (rank : 61)	NC score	0.592975 (rank : 59)
Query Neighborhood Hits	165	Target Neighborhood Hits	141	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

CO8B_HUMAN
θ value	5.26297e-08 (rank : 62)	NC score	0.509958 (rank : 67)
Query Neighborhood Hits	165	Target Neighborhood Hits	199	Shared Neighborhood Hits	78
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO8A_HUMAN
θ value	9.92553e-07 (rank : 63)	NC score	0.508495 (rank : 68)
Query Neighborhood Hits	165	Target Neighborhood Hits	200	Shared Neighborhood Hits	82
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO6_HUMAN
θ value	2.88788e-06 (rank : 64)	NC score	0.523401 (rank : 66)
Query Neighborhood Hits	165	Target Neighborhood Hits	331	Shared Neighborhood Hits	95
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CO7_HUMAN
θ value	8.40245e-06 (rank : 65)	NC score	0.480371 (rank : 71)
Query Neighborhood Hits	165	Target Neighborhood Hits	278	Shared Neighborhood Hits	81
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

FRAS1_HUMAN
θ value	3.19293e-05 (rank : 66)	NC score	0.151699 (rank : 95)
Query Neighborhood Hits	165	Target Neighborhood Hits	759	Shared Neighborhood Hits	83
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

ATL1_HUMAN
θ value	4.1701e-05 (rank : 67)	NC score	0.620948 (rank : 50)
Query Neighborhood Hits	165	Target Neighborhood Hits	93	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N6G6, Q5T708, Q96RW4, Q9BXY3	Gene names	ADAMTSL1, ADAMTSR1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (ADAMTSL-1) (Punctin-1).

CO8A_MOUSE
θ value	4.1701e-05 (rank : 68)	NC score	0.499682 (rank : 70)
Query Neighborhood Hits	165	Target Neighborhood Hits	182	Shared Neighborhood Hits	77
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

ATL1_MOUSE
θ value	5.44631e-05 (rank : 69)	NC score	0.618039 (rank : 52)
Query Neighborhood Hits	165	Target Neighborhood Hits	80	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BLI0	Gene names	Adamtsl1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (Punctin-1).

THSD1_MOUSE
θ value	0.000121331 (rank : 70)	NC score	0.553526 (rank : 64)
Query Neighborhood Hits	165	Target Neighborhood Hits	153	Shared Neighborhood Hits	74
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

ATL5_HUMAN
θ value	0.00020696 (rank : 71)	NC score	0.629272 (rank : 39)
Query Neighborhood Hits	165	Target Neighborhood Hits	103	Shared Neighborhood Hits	72
SwissProt Accessions	Q6ZMM2, Q8IW95	Gene names	ADAMTSL5, THSD6
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 5 precursor (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6).

CILP1_HUMAN
θ value	0.000270298 (rank : 72)	NC score	0.389824 (rank : 75)
Query Neighborhood Hits	165	Target Neighborhood Hits	266	Shared Neighborhood Hits	83
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

THSD1_HUMAN
θ value	0.00035302 (rank : 73)	NC score	0.571962 (rank : 62)
Query Neighborhood Hits	165	Target Neighborhood Hits	136	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

NOTC4_HUMAN
θ value	0.000786445 (rank : 74)	NC score	0.077987 (rank : 231)
Query Neighborhood Hits	165	Target Neighborhood Hits	905	Shared Neighborhood Hits	60
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

UNC5A_HUMAN
θ value	0.000786445 (rank : 75)	NC score	0.555886 (rank : 63)
Query Neighborhood Hits	165	Target Neighborhood Hits	198	Shared Neighborhood Hits	74
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

NOTC4_MOUSE
θ value	0.00509761 (rank : 76)	NC score	0.074181 (rank : 245)
Query Neighborhood Hits	165	Target Neighborhood Hits	872	Shared Neighborhood Hits	56
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

PIGQ_HUMAN
θ value	0.00665767 (rank : 77)	NC score	0.057920 (rank : 364)
Query Neighborhood Hits	165	Target Neighborhood Hits	84	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BRB3, O14927, Q96G00, Q96S22, Q9UJH4	Gene names	PIGQ, GPI1
Domain Architecture
Description	Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q (EC 2.4.1.198) (Phosphatidylinositol-glycan biosynthesis class Q protein) (PIG-Q) (N-acetylglucosamyl transferase component GPI1).

CILP1_MOUSE
θ value	0.00869519 (rank : 78)	NC score	0.398261 (rank : 74)
Query Neighborhood Hits	165	Target Neighborhood Hits	282	Shared Neighborhood Hits	79
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

NOTC3_HUMAN
θ value	0.0113563 (rank : 79)	NC score	0.082538 (rank : 220)
Query Neighborhood Hits	165	Target Neighborhood Hits	1062	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

RSPO2_HUMAN
θ value	0.0113563 (rank : 80)	NC score	0.148945 (rank : 98)
Query Neighborhood Hits	165	Target Neighborhood Hits	90	Shared Neighborhood Hits	39
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

RSPO4_MOUSE
θ value	0.0113563 (rank : 81)	NC score	0.197268 (rank : 78)
Query Neighborhood Hits	165	Target Neighborhood Hits	110	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

TENX_HUMAN
θ value	0.0252991 (rank : 82)	NC score	0.080788 (rank : 222)
Query Neighborhood Hits	165	Target Neighborhood Hits	789	Shared Neighborhood Hits	66
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

MEGF6_HUMAN
θ value	0.0330416 (rank : 83)	NC score	0.092932 (rank : 187)
Query Neighborhood Hits	165	Target Neighborhood Hits	671	Shared Neighborhood Hits	73
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

KR107_HUMAN
θ value	0.0431538 (rank : 84)	NC score	0.101843 (rank : 154)
Query Neighborhood Hits	165	Target Neighborhood Hits	330	Shared Neighborhood Hits	41
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

RSPO1_HUMAN
θ value	0.0431538 (rank : 85)	NC score	0.216539 (rank : 77)
Query Neighborhood Hits	165	Target Neighborhood Hits	101	Shared Neighborhood Hits	51
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

CI094_HUMAN
θ value	0.0736092 (rank : 86)	NC score	0.453166 (rank : 72)
Query Neighborhood Hits	165	Target Neighborhood Hits	310	Shared Neighborhood Hits	72
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

FRAS1_MOUSE
θ value	0.0736092 (rank : 87)	NC score	0.162521 (rank : 84)
Query Neighborhood Hits	165	Target Neighborhood Hits	747	Shared Neighborhood Hits	89
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

RSPO2_MOUSE
θ value	0.0736092 (rank : 88)	NC score	0.135181 (rank : 110)
Query Neighborhood Hits	165	Target Neighborhood Hits	88	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

CN032_HUMAN
θ value	0.125558 (rank : 89)	NC score	0.026459 (rank : 422)
Query Neighborhood Hits	165	Target Neighborhood Hits	267	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

DRD4_HUMAN
θ value	0.125558 (rank : 90)	NC score	0.001702 (rank : 458)
Query Neighborhood Hits	165	Target Neighborhood Hits	886	Shared Neighborhood Hits	9
SwissProt Accessions	P21917	Gene names	DRD4
Domain Architecture
Description	D(4) dopamine receptor (Dopamine D4 receptor) (D(2C) dopamine receptor).

PCSK5_MOUSE
θ value	0.163984 (rank : 91)	NC score	0.094093 (rank : 183)
Query Neighborhood Hits	165	Target Neighborhood Hits	613	Shared Neighborhood Hits	65
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

RSPO1_MOUSE
θ value	0.163984 (rank : 92)	NC score	0.189627 (rank : 79)
Query Neighborhood Hits	165	Target Neighborhood Hits	85	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

RSPO4_HUMAN
θ value	0.163984 (rank : 93)	NC score	0.169573 (rank : 83)
Query Neighborhood Hits	165	Target Neighborhood Hits	110	Shared Neighborhood Hits	40
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

TNR9_HUMAN
θ value	0.21417 (rank : 94)	NC score	0.041046 (rank : 413)
Query Neighborhood Hits	165	Target Neighborhood Hits	166	Shared Neighborhood Hits	18
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

LYAM2_MOUSE
θ value	0.279714 (rank : 95)	NC score	0.037464 (rank : 416)
Query Neighborhood Hits	165	Target Neighborhood Hits	420	Shared Neighborhood Hits	37
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

KRA51_HUMAN
θ value	0.365318 (rank : 96)	NC score	0.107384 (rank : 142)
Query Neighborhood Hits	165	Target Neighborhood Hits	288	Shared Neighborhood Hits	44
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

RSPO3_HUMAN
θ value	0.365318 (rank : 97)	NC score	0.183428 (rank : 81)
Query Neighborhood Hits	165	Target Neighborhood Hits	128	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

RSPO3_MOUSE
θ value	0.365318 (rank : 98)	NC score	0.182787 (rank : 82)
Query Neighborhood Hits	165	Target Neighborhood Hits	120	Shared Neighborhood Hits	42
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

HXA3_MOUSE
θ value	0.47712 (rank : 99)	NC score	0.005521 (rank : 453)
Query Neighborhood Hits	165	Target Neighborhood Hits	558	Shared Neighborhood Hits	7
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

DLL1_MOUSE
θ value	0.62314 (rank : 100)	NC score	0.071523 (rank : 264)
Query Neighborhood Hits	165	Target Neighborhood Hits	456	Shared Neighborhood Hits	50
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

PGBM_MOUSE
θ value	0.62314 (rank : 101)	NC score	0.062548 (rank : 331)
Query Neighborhood Hits	165	Target Neighborhood Hits	1073	Shared Neighborhood Hits	58
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

ATRN_MOUSE
θ value	0.813845 (rank : 102)	NC score	0.036440 (rank : 417)
Query Neighborhood Hits	165	Target Neighborhood Hits	519	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

CIC_MOUSE
θ value	0.813845 (rank : 103)	NC score	0.016132 (rank : 427)
Query Neighborhood Hits	165	Target Neighborhood Hits	742	Shared Neighborhood Hits	21
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

HCN2_HUMAN
θ value	0.813845 (rank : 104)	NC score	0.006897 (rank : 448)
Query Neighborhood Hits	165	Target Neighborhood Hits	369	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

JPH4_MOUSE
θ value	0.813845 (rank : 105)	NC score	0.011975 (rank : 440)
Query Neighborhood Hits	165	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	Q80WT0, Q8BMI1	Gene names	Jph4, Jphl1
Domain Architecture	No domain graphic available
Description	Junctophilin-4 (Junctophilin-like 1 protein).

NMDE3_HUMAN
θ value	0.813845 (rank : 106)	NC score	0.008533 (rank : 444)
Query Neighborhood Hits	165	Target Neighborhood Hits	110	Shared Neighborhood Hits	7
SwissProt Accessions	Q14957	Gene names	GRIN2C
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

WDR43_HUMAN
θ value	0.813845 (rank : 107)	NC score	0.012493 (rank : 436)
Query Neighborhood Hits	165	Target Neighborhood Hits	269	Shared Neighborhood Hits	4
SwissProt Accessions	Q15061, Q15395, Q92577	Gene names	WDR43, KIAA0007
Domain Architecture	No domain graphic available
Description	WD repeat protein 43.

CO9_MOUSE
θ value	1.06291 (rank : 108)	NC score	0.160593 (rank : 87)
Query Neighborhood Hits	165	Target Neighborhood Hits	153	Shared Neighborhood Hits	32
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

CSKI2_HUMAN
θ value	1.06291 (rank : 109)	NC score	0.007026 (rank : 446)
Query Neighborhood Hits	165	Target Neighborhood Hits	747	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

KR106_HUMAN
θ value	1.06291 (rank : 110)	NC score	0.112368 (rank : 131)
Query Neighborhood Hits	165	Target Neighborhood Hits	347	Shared Neighborhood Hits	51
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

LRP8_HUMAN
θ value	1.06291 (rank : 111)	NC score	0.070591 (rank : 268)
Query Neighborhood Hits	165	Target Neighborhood Hits	346	Shared Neighborhood Hits	36
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

SREC_HUMAN
θ value	1.38821 (rank : 112)	NC score	0.074831 (rank : 242)
Query Neighborhood Hits	165	Target Neighborhood Hits	645	Shared Neighborhood Hits	63
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

STAB2_MOUSE
θ value	1.38821 (rank : 113)	NC score	0.084182 (rank : 212)
Query Neighborhood Hits	165	Target Neighborhood Hits	528	Shared Neighborhood Hits	52
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

CJ078_MOUSE
θ value	1.81305 (rank : 114)	NC score	0.007391 (rank : 445)
Query Neighborhood Hits	165	Target Neighborhood Hits	559	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

ERBB3_HUMAN
θ value	1.81305 (rank : 115)	NC score	0.005035 (rank : 454)
Query Neighborhood Hits	165	Target Neighborhood Hits	918	Shared Neighborhood Hits	25
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

NOTC3_MOUSE
θ value	1.81305 (rank : 116)	NC score	0.083306 (rank : 216)
Query Neighborhood Hits	165	Target Neighborhood Hits	975	Shared Neighborhood Hits	71
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

TF7L1_HUMAN
θ value	1.81305 (rank : 117)	NC score	0.013656 (rank : 432)
Query Neighborhood Hits	165	Target Neighborhood Hits	129	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HCS4, Q53R97, Q6PD70, Q9NP00	Gene names	TCF7L1, TCF3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF- 3).

TF7L1_MOUSE
θ value	1.81305 (rank : 118)	NC score	0.013680 (rank : 430)
Query Neighborhood Hits	165	Target Neighborhood Hits	131	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1J1, O70450, O70573	Gene names	Tcf7l1, Tcf3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF-3) (mTCF-3).

WISP2_HUMAN
θ value	1.81305 (rank : 119)	NC score	0.145442 (rank : 99)
Query Neighborhood Hits	165	Target Neighborhood Hits	126	Shared Neighborhood Hits	56
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

KRA11_HUMAN
θ value	2.36792 (rank : 120)	NC score	0.056153 (rank : 373)
Query Neighborhood Hits	165	Target Neighborhood Hits	155	Shared Neighborhood Hits	26
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

LCE1A_HUMAN
θ value	2.36792 (rank : 121)	NC score	0.076322 (rank : 236)
Query Neighborhood Hits	165	Target Neighborhood Hits	47	Shared Neighborhood Hits	10
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

NFX1_HUMAN
θ value	2.36792 (rank : 122)	NC score	0.067886 (rank : 288)
Query Neighborhood Hits	165	Target Neighborhood Hits	405	Shared Neighborhood Hits	37
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

PGBM_HUMAN
θ value	2.36792 (rank : 123)	NC score	0.066174 (rank : 301)
Query Neighborhood Hits	165	Target Neighborhood Hits	1113	Shared Neighborhood Hits	59
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

ASXL1_MOUSE
θ value	3.0926 (rank : 124)	NC score	0.012144 (rank : 438)
Query Neighborhood Hits	165	Target Neighborhood Hits	182	Shared Neighborhood Hits	6
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

CF136_HUMAN
θ value	3.0926 (rank : 125)	NC score	0.028691 (rank : 421)
Query Neighborhood Hits	165	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q5SQH8, Q5SU01, Q6ZSB7, Q8TB84	Gene names	C6orf136
Domain Architecture	No domain graphic available
Description	Protein C6orf136.

KR101_HUMAN
θ value	3.0926 (rank : 126)	NC score	0.096808 (rank : 170)
Query Neighborhood Hits	165	Target Neighborhood Hits	261	Shared Neighborhood Hits	38
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

MAP1A_HUMAN
θ value	3.0926 (rank : 127)	NC score	0.004550 (rank : 455)
Query Neighborhood Hits	165	Target Neighborhood Hits	1626	Shared Neighborhood Hits	24
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

PCX3_MOUSE
θ value	3.0926 (rank : 128)	NC score	0.012972 (rank : 435)
Query Neighborhood Hits	165	Target Neighborhood Hits	134	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VI59	Gene names	Pcnxl3
Domain Architecture
Description	Pecanex-like protein 3.

REXO1_HUMAN
θ value	3.0926 (rank : 129)	NC score	0.008722 (rank : 443)
Query Neighborhood Hits	165	Target Neighborhood Hits	242	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

SFPQ_HUMAN
θ value	3.0926 (rank : 130)	NC score	0.006222 (rank : 452)
Query Neighborhood Hits	165	Target Neighborhood Hits	986	Shared Neighborhood Hits	11
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SFPQ_MOUSE
θ value	3.0926 (rank : 131)	NC score	0.006379 (rank : 450)
Query Neighborhood Hits	165	Target Neighborhood Hits	958	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

UBE4B_HUMAN
θ value	3.0926 (rank : 132)	NC score	0.011004 (rank : 442)
Query Neighborhood Hits	165	Target Neighborhood Hits	158	Shared Neighborhood Hits	5
SwissProt Accessions	O95155, O75169, O95338, Q5SZ12, Q5SZ16, Q96QD4, Q9BYI7	Gene names	UBE4B, HDNB1, KIAA0684, UFD2
Domain Architecture
Description	Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Homozygously deleted in neuroblastoma 1).

WISP2_MOUSE
θ value	3.0926 (rank : 133)	NC score	0.143343 (rank : 102)
Query Neighborhood Hits	165	Target Neighborhood Hits	129	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

ADA1B_MOUSE
θ value	4.03905 (rank : 134)	NC score	-0.005207 (rank : 463)
Query Neighborhood Hits	165	Target Neighborhood Hits	966	Shared Neighborhood Hits	3
SwissProt Accessions	P97717	Gene names	Adra1b
Domain Architecture
Description	Alpha-1B adrenergic receptor (Alpha 1B-adrenoceptor) (Alpha 1B- adrenoreceptor).

ASPH_HUMAN
θ value	4.03905 (rank : 135)	NC score	0.012159 (rank : 437)
Query Neighborhood Hits	165	Target Neighborhood Hits	158	Shared Neighborhood Hits	2
SwissProt Accessions	Q12797	Gene names	ASPH
Domain Architecture
Description	Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta- hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta- dioxygenase).

ERBB4_HUMAN
θ value	4.03905 (rank : 136)	NC score	0.000539 (rank : 461)
Query Neighborhood Hits	165	Target Neighborhood Hits	910	Shared Neighborhood Hits	21
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

NFAC1_HUMAN
θ value	4.03905 (rank : 137)	NC score	0.011934 (rank : 441)
Query Neighborhood Hits	165	Target Neighborhood Hits	312	Shared Neighborhood Hits	12
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

SYN1_MOUSE
θ value	4.03905 (rank : 138)	NC score	0.004036 (rank : 456)
Query Neighborhood Hits	165	Target Neighborhood Hits	363	Shared Neighborhood Hits	6
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

TTDN1_HUMAN
θ value	4.03905 (rank : 139)	NC score	0.015437 (rank : 428)
Query Neighborhood Hits	165	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TAP9	Gene names	TTDN1, C7orf11
Domain Architecture	No domain graphic available
Description	TTD non-photosensitive 1 protein.

ITB2_HUMAN
θ value	5.27518 (rank : 140)	NC score	0.020989 (rank : 423)
Query Neighborhood Hits	165	Target Neighborhood Hits	282	Shared Neighborhood Hits	28
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

LAMA3_MOUSE
θ value	5.27518 (rank : 141)	NC score	0.032612 (rank : 419)
Query Neighborhood Hits	165	Target Neighborhood Hits	859	Shared Neighborhood Hits	47
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

ODFP_HUMAN
θ value	5.27518 (rank : 142)	NC score	0.016684 (rank : 426)
Query Neighborhood Hits	165	Target Neighborhood Hits	32	Shared Neighborhood Hits	6
SwissProt Accessions	Q14990	Gene names	ODF1, ODFP
Domain Architecture
Description	Outer dense fiber protein.

PKD1_HUMAN
θ value	5.27518 (rank : 143)	NC score	0.006243 (rank : 451)
Query Neighborhood Hits	165	Target Neighborhood Hits	387	Shared Neighborhood Hits	6
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

TB182_HUMAN
θ value	5.27518 (rank : 144)	NC score	0.015365 (rank : 429)
Query Neighborhood Hits	165	Target Neighborhood Hits	414	Shared Neighborhood Hits	8
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

CAC1C_HUMAN
θ value	6.88961 (rank : 145)	NC score	0.001055 (rank : 459)
Query Neighborhood Hits	165	Target Neighborhood Hits	158	Shared Neighborhood Hits	3
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

CJ095_HUMAN
θ value	6.88961 (rank : 146)	NC score	0.044011 (rank : 411)
Query Neighborhood Hits	165	Target Neighborhood Hits	50	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H7T3	Gene names	C10orf95
Domain Architecture	No domain graphic available
Description	Protein C10orf95.

IRS2_MOUSE
θ value	6.88961 (rank : 147)	NC score	0.006664 (rank : 449)
Query Neighborhood Hits	165	Target Neighborhood Hits	248	Shared Neighborhood Hits	9
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

MEGF9_HUMAN
θ value	6.88961 (rank : 148)	NC score	0.040716 (rank : 414)
Query Neighborhood Hits	165	Target Neighborhood Hits	557	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MTF1_HUMAN
θ value	6.88961 (rank : 149)	NC score	-0.007135 (rank : 465)
Query Neighborhood Hits	165	Target Neighborhood Hits	814	Shared Neighborhood Hits	4
SwissProt Accessions	Q14872, Q96CB1	Gene names	MTF1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

ODFP_MOUSE
θ value	6.88961 (rank : 150)	NC score	0.018742 (rank : 425)
Query Neighborhood Hits	165	Target Neighborhood Hits	75	Shared Neighborhood Hits	14
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

PRR13_HUMAN
θ value	6.88961 (rank : 151)	NC score	0.012082 (rank : 439)
Query Neighborhood Hits	165	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

RX_HUMAN
θ value	6.88961 (rank : 152)	NC score	-0.001938 (rank : 462)
Query Neighborhood Hits	165	Target Neighborhood Hits	423	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2V3	Gene names	RAX, RX
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

ZEP1_MOUSE
θ value	6.88961 (rank : 153)	NC score	-0.005308 (rank : 464)
Query Neighborhood Hits	165	Target Neighborhood Hits	1063	Shared Neighborhood Hits	10
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

ATRN_HUMAN
θ value	8.99809 (rank : 154)	NC score	0.038344 (rank : 415)
Query Neighborhood Hits	165	Target Neighborhood Hits	525	Shared Neighborhood Hits	38
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

BORG5_HUMAN
θ value	8.99809 (rank : 155)	NC score	0.013657 (rank : 431)
Query Neighborhood Hits	165	Target Neighborhood Hits	135	Shared Neighborhood Hits	8
SwissProt Accessions	Q00587, Q96GN1	Gene names	CDC42EP1, BORG5, CEP1, MSE55
Domain Architecture
Description	Cdc42 effector protein 1 (Binder of Rho GTPases 5) (Serum protein MSE55).

CD2A2_HUMAN
θ value	8.99809 (rank : 156)	NC score	0.013157 (rank : 434)
Query Neighborhood Hits	165	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N726, Q13195, Q13399, Q16360, Q7KZR9	Gene names	CDKN2A
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase inhibitor 2A, isoform 4 (p14ARF) (p19ARF).

CIC_HUMAN
θ value	8.99809 (rank : 157)	NC score	0.006918 (rank : 447)
Query Neighborhood Hits	165	Target Neighborhood Hits	992	Shared Neighborhood Hits	18
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CN032_MOUSE
θ value	8.99809 (rank : 158)	NC score	0.013495 (rank : 433)
Query Neighborhood Hits	165	Target Neighborhood Hits	233	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

FA12_HUMAN
θ value	8.99809 (rank : 159)	NC score	0.003871 (rank : 457)
Query Neighborhood Hits	165	Target Neighborhood Hits	425	Shared Neighborhood Hits	18
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

KRA92_HUMAN
θ value	8.99809 (rank : 160)	NC score	0.076692 (rank : 235)
Query Neighborhood Hits	165	Target Neighborhood Hits	198	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

LAMC1_HUMAN
θ value	8.99809 (rank : 161)	NC score	0.036066 (rank : 418)
Query Neighborhood Hits	165	Target Neighborhood Hits	922	Shared Neighborhood Hits	43
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

MK_MOUSE
θ value	8.99809 (rank : 162)	NC score	0.041745 (rank : 412)
Query Neighborhood Hits	165	Target Neighborhood Hits	21	Shared Neighborhood Hits	16
SwissProt Accessions	P12025	Gene names	Mdk, Mk
Domain Architecture
Description	Midkine precursor (MK) (Retinoic acid-induced differentiation factor).

PDE6A_HUMAN
θ value	8.99809 (rank : 163)	NC score	0.000965 (rank : 460)
Query Neighborhood Hits	165	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	P16499	Gene names	PDE6A, PDEA
Domain Architecture
Description	Rod cGMP-specific 3',5'-cyclic phosphodiesterase alpha-subunit (EC 3.1.4.35) (GMP-PDE alpha) (PDE V-B1).

SPR2I_MOUSE
θ value	8.99809 (rank : 164)	NC score	0.029803 (rank : 420)
Query Neighborhood Hits	165	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

TNR8_MOUSE
θ value	8.99809 (rank : 165)	NC score	0.020837 (rank : 424)
Query Neighborhood Hits	165	Target Neighborhood Hits	208	Shared Neighborhood Hits	19
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

AD26A_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.099484 (rank : 166)
Query Neighborhood Hits	165	Target Neighborhood Hits	165	Shared Neighborhood Hits	44
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

ADA10_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.074826 (rank : 243)
Query Neighborhood Hits	165	Target Neighborhood Hits	189	Shared Neighborhood Hits	40
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ADA10_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.072490 (rank : 259)
Query Neighborhood Hits	165	Target Neighborhood Hits	194	Shared Neighborhood Hits	40
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA11_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.086962 (rank : 204)
Query Neighborhood Hits	165	Target Neighborhood Hits	259	Shared Neighborhood Hits	47
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA11_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.100252 (rank : 160)
Query Neighborhood Hits	165	Target Neighborhood Hits	263	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA12_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.140046 (rank : 104)
Query Neighborhood Hits	165	Target Neighborhood Hits	224	Shared Neighborhood Hits	45
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA12_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.139337 (rank : 105)
Query Neighborhood Hits	165	Target Neighborhood Hits	474	Shared Neighborhood Hits	59
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA15_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.133539 (rank : 112)
Query Neighborhood Hits	165	Target Neighborhood Hits	288	Shared Neighborhood Hits	56
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

ADA15_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.118299 (rank : 125)
Query Neighborhood Hits	165	Target Neighborhood Hits	324	Shared Neighborhood Hits	56
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADA17_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.075258 (rank : 241)
Query Neighborhood Hits	165	Target Neighborhood Hits	223	Shared Neighborhood Hits	43
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ADA17_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.076781 (rank : 234)
Query Neighborhood Hits	165	Target Neighborhood Hits	201	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

ADA18_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.060404 (rank : 350)
Query Neighborhood Hits	165	Target Neighborhood Hits	184	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

ADA18_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.073499 (rank : 251)
Query Neighborhood Hits	165	Target Neighborhood Hits	227	Shared Neighborhood Hits	45
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ADA19_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.148972 (rank : 97)
Query Neighborhood Hits	165	Target Neighborhood Hits	381	Shared Neighborhood Hits	60
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ADA19_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.157946 (rank : 92)
Query Neighborhood Hits	165	Target Neighborhood Hits	315	Shared Neighborhood Hits	59
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ADA20_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.075741 (rank : 240)
Query Neighborhood Hits	165	Target Neighborhood Hits	143	Shared Neighborhood Hits	38
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

ADA21_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.101035 (rank : 159)
Query Neighborhood Hits	165	Target Neighborhood Hits	181	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

ADA21_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.108962 (rank : 138)
Query Neighborhood Hits	165	Target Neighborhood Hits	172	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

ADA22_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.112578 (rank : 130)
Query Neighborhood Hits	165	Target Neighborhood Hits	211	Shared Neighborhood Hits	45
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ADA22_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.106866 (rank : 144)
Query Neighborhood Hits	165	Target Neighborhood Hits	225	Shared Neighborhood Hits	46
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ADA23_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.104063 (rank : 149)
Query Neighborhood Hits	165	Target Neighborhood Hits	235	Shared Neighborhood Hits	45
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA23_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.107530 (rank : 141)
Query Neighborhood Hits	165	Target Neighborhood Hits	245	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA24_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.108298 (rank : 139)
Query Neighborhood Hits	165	Target Neighborhood Hits	230	Shared Neighborhood Hits	52
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ADA25_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.102213 (rank : 153)
Query Neighborhood Hits	165	Target Neighborhood Hits	213	Shared Neighborhood Hits	45
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

ADA28_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.144486 (rank : 100)
Query Neighborhood Hits	165	Target Neighborhood Hits	244	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ADA28_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.149058 (rank : 96)
Query Neighborhood Hits	165	Target Neighborhood Hits	241	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ADA29_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.101628 (rank : 155)
Query Neighborhood Hits	165	Target Neighborhood Hits	247	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

ADA30_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.052558 (rank : 392)
Query Neighborhood Hits	165	Target Neighborhood Hits	391	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ADA32_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.079420 (rank : 226)
Query Neighborhood Hits	165	Target Neighborhood Hits	216	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA32_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.075836 (rank : 239)
Query Neighborhood Hits	165	Target Neighborhood Hits	219	Shared Neighborhood Hits	46
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA33_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.144308 (rank : 101)
Query Neighborhood Hits	165	Target Neighborhood Hits	264	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA33_MOUSE
θ value	θ > 10 (rank : 197)	NC score	0.130449 (rank : 114)
Query Neighborhood Hits	165	Target Neighborhood Hits	231	Shared Neighborhood Hits	54
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADAM2_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.060600 (rank : 348)
Query Neighborhood Hits	165	Target Neighborhood Hits	175	Shared Neighborhood Hits	35
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

ADAM2_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.082770 (rank : 219)
Query Neighborhood Hits	165	Target Neighborhood Hits	209	Shared Neighborhood Hits	47
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

ADAM7_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.129209 (rank : 116)
Query Neighborhood Hits	165	Target Neighborhood Hits	221	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ADAM7_MOUSE
θ value	θ > 10 (rank : 201)	NC score	0.129853 (rank : 115)
Query Neighborhood Hits	165	Target Neighborhood Hits	200	Shared Neighborhood Hits	49
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADAM8_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.160951 (rank : 86)
Query Neighborhood Hits	165	Target Neighborhood Hits	327	Shared Neighborhood Hits	60
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ADAM8_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.160144 (rank : 88)
Query Neighborhood Hits	165	Target Neighborhood Hits	326	Shared Neighborhood Hits	63
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

ADAM9_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.128590 (rank : 117)
Query Neighborhood Hits	165	Target Neighborhood Hits	243	Shared Neighborhood Hits	48
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

ADAM9_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.135416 (rank : 109)
Query Neighborhood Hits	165	Target Neighborhood Hits	325	Shared Neighborhood Hits	50
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ADEC1_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.136426 (rank : 106)
Query Neighborhood Hits	165	Target Neighborhood Hits	80	Shared Neighborhood Hits	27
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADEC1_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.109097 (rank : 137)
Query Neighborhood Hits	165	Target Neighborhood Hits	85	Shared Neighborhood Hits	28
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADM1A_MOUSE
θ value	θ > 10 (rank : 208)	NC score	0.107617 (rank : 140)
Query Neighborhood Hits	165	Target Neighborhood Hits	230	Shared Neighborhood Hits	50
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ADM1B_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.111347 (rank : 134)
Query Neighborhood Hits	165	Target Neighborhood Hits	236	Shared Neighborhood Hits	48
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

AGRIN_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.053922 (rank : 382)
Query Neighborhood Hits	165	Target Neighborhood Hits	582	Shared Neighborhood Hits	49
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

BMPER_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.089838 (rank : 194)
Query Neighborhood Hits	165	Target Neighborhood Hits	175	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

BMPER_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.083941 (rank : 214)
Query Neighborhood Hits	165	Target Neighborhood Hits	194	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

C1QR1_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.067698 (rank : 289)
Query Neighborhood Hits	165	Target Neighborhood Hits	493	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.068629 (rank : 278)
Query Neighborhood Hits	165	Target Neighborhood Hits	342	Shared Neighborhood Hits	30
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

CALCR_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.066719 (rank : 296)
Query Neighborhood Hits	165	Target Neighborhood Hits	67	Shared Neighborhood Hits	6
SwissProt Accessions	P30988, O14585, Q13941, Q6DJU8, Q6T712	Gene names	CALCR
Domain Architecture
Description	Calcitonin receptor precursor (CT-R).

CALCR_MOUSE
θ value	θ > 10 (rank : 216)	NC score	0.053002 (rank : 387)
Query Neighborhood Hits	165	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	Q60755	Gene names	Calcr
Domain Architecture
Description	Calcitonin receptor precursor (CT-R).

CD97_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.124441 (rank : 120)
Query Neighborhood Hits	165	Target Neighborhood Hits	353	Shared Neighborhood Hits	31
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CD97_MOUSE
θ value	θ > 10 (rank : 218)	NC score	0.118016 (rank : 126)
Query Neighborhood Hits	165	Target Neighborhood Hits	295	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CDON_MOUSE
θ value	θ > 10 (rank : 219)	NC score	0.050120 (rank : 410)
Query Neighborhood Hits	165	Target Neighborhood Hits	410	Shared Neighborhood Hits	17
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

CELR1_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.072628 (rank : 256)
Query Neighborhood Hits	165	Target Neighborhood Hits	613	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CELR1_MOUSE
θ value	θ > 10 (rank : 221)	NC score	0.072520 (rank : 258)
Query Neighborhood Hits	165	Target Neighborhood Hits	617	Shared Neighborhood Hits	38
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

CELR2_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.079256 (rank : 227)
Query Neighborhood Hits	165	Target Neighborhood Hits	657	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CELR2_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.071961 (rank : 262)
Query Neighborhood Hits	165	Target Neighborhood Hits	584	Shared Neighborhood Hits	39
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

CELR3_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.068617 (rank : 279)
Query Neighborhood Hits	165	Target Neighborhood Hits	680	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CELR3_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.067532 (rank : 290)
Query Neighborhood Hits	165	Target Neighborhood Hits	687	Shared Neighborhood Hits	51
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

CHRD_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.055353 (rank : 376)
Query Neighborhood Hits	165	Target Neighborhood Hits	102	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

CHRD_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.052581 (rank : 391)
Query Neighborhood Hits	165	Target Neighborhood Hits	102	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

CO9_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.136010 (rank : 108)
Query Neighborhood Hits	165	Target Neighborhood Hits	147	Shared Neighborhood Hits	24
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

COMP_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.159621 (rank : 90)
Query Neighborhood Hits	165	Target Neighborhood Hits	258	Shared Neighborhood Hits	26
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

COMP_MOUSE
θ value	θ > 10 (rank : 230)	NC score	0.159528 (rank : 91)
Query Neighborhood Hits	165	Target Neighborhood Hits	290	Shared Neighborhood Hits	29
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CRDL1_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.056145 (rank : 374)
Query Neighborhood Hits	165	Target Neighborhood Hits	75	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BU40, Q9Y3H7	Gene names	CHRDL1, NRLN1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CRDL1_MOUSE
θ value	θ > 10 (rank : 232)	NC score	0.054439 (rank : 378)
Query Neighborhood Hits	165	Target Neighborhood Hits	81	Shared Neighborhood Hits	11
SwissProt Accessions	Q920C1, Q924K0, Q9EPZ9	Gene names	Chrdl1, Ng1, Nrln1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CRDL2_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.066840 (rank : 295)
Query Neighborhood Hits	165	Target Neighborhood Hits	99	Shared Neighborhood Hits	14
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

CRDL2_MOUSE
θ value	θ > 10 (rank : 234)	NC score	0.074161 (rank : 246)
Query Neighborhood Hits	165	Target Neighborhood Hits	81	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

CREL1_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.071035 (rank : 266)
Query Neighborhood Hits	165	Target Neighborhood Hits	441	Shared Neighborhood Hits	37
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
θ value	θ > 10 (rank : 236)	NC score	0.073190 (rank : 255)
Query Neighborhood Hits	165	Target Neighborhood Hits	524	Shared Neighborhood Hits	40
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CRFR1_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.069707 (rank : 272)
Query Neighborhood Hits	165	Target Neighborhood Hits	82	Shared Neighborhood Hits	6
SwissProt Accessions	P34998, Q13008, Q9UK64	Gene names	CRHR1, CRFR, CRFR1, CRHR
Domain Architecture
Description	Corticotropin-releasing factor receptor 1 precursor (CRF-R) (CRF1) (Corticotropin-releasing hormone receptor 1) (CRH-R 1).

CRFR1_MOUSE
θ value	θ > 10 (rank : 238)	NC score	0.069524 (rank : 274)
Query Neighborhood Hits	165	Target Neighborhood Hits	83	Shared Neighborhood Hits	6
SwissProt Accessions	P35347	Gene names	Crhr1, Crhr
Domain Architecture
Description	Corticotropin-releasing factor receptor 1 precursor (CRF-R) (CRF1) (Corticotropin-releasing hormone receptor 1) (CRH-R 1).

CRFR2_HUMAN
θ value	θ > 10 (rank : 239)	NC score	0.068491 (rank : 280)
Query Neighborhood Hits	165	Target Neighborhood Hits	76	Shared Neighborhood Hits	7
SwissProt Accessions	Q13324, O43461, Q99431	Gene names	CRHR2, CRF2R, CRH2R
Domain Architecture
Description	Corticotropin-releasing factor receptor 2 precursor (CRF-R 2) (CRF2) (Corticotropin-releasing hormone receptor 2) (CRH-R 2).

CRFR2_MOUSE
θ value	θ > 10 (rank : 240)	NC score	0.065458 (rank : 305)
Query Neighborhood Hits	165	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	Q60748, Q60783, Q60808	Gene names	Crhr2, Crf2r
Domain Architecture
Description	Corticotropin-releasing factor receptor 2 precursor (CRF-R 2) (CRF2) (Corticotropin-releasing hormone receptor 2) (CRH-R 2) (CRF-RB) (CRH- R2).

CRIM1_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.104419 (rank : 147)
Query Neighborhood Hits	165	Target Neighborhood Hits	362	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

CRUM1_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.063951 (rank : 318)
Query Neighborhood Hits	165	Target Neighborhood Hits	457	Shared Neighborhood Hits	48
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM1_MOUSE
θ value	θ > 10 (rank : 243)	NC score	0.061770 (rank : 340)
Query Neighborhood Hits	165	Target Neighborhood Hits	444	Shared Neighborhood Hits	48
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CRUM2_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.063200 (rank : 322)
Query Neighborhood Hits	165	Target Neighborhood Hits	453	Shared Neighborhood Hits	43
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

CTGF_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.078991 (rank : 228)
Query Neighborhood Hits	165	Target Neighborhood Hits	128	Shared Neighborhood Hits	48
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

CTGF_MOUSE
θ value	θ > 10 (rank : 246)	NC score	0.078581 (rank : 230)
Query Neighborhood Hits	165	Target Neighborhood Hits	124	Shared Neighborhood Hits	46
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

CUBN_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.063982 (rank : 316)
Query Neighborhood Hits	165	Target Neighborhood Hits	482	Shared Neighborhood Hits	40
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CUBN_MOUSE
θ value	θ > 10 (rank : 248)	NC score	0.067417 (rank : 291)
Query Neighborhood Hits	165	Target Neighborhood Hits	477	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CYR61_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.111744 (rank : 133)
Query Neighborhood Hits	165	Target Neighborhood Hits	159	Shared Neighborhood Hits	60
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

CYR61_MOUSE
θ value	θ > 10 (rank : 250)	NC score	0.094725 (rank : 179)
Query Neighborhood Hits	165	Target Neighborhood Hits	156	Shared Neighborhood Hits	55
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

DLK_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.052813 (rank : 389)
Query Neighborhood Hits	165	Target Neighborhood Hits	401	Shared Neighborhood Hits	41
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLK_MOUSE
θ value	θ > 10 (rank : 252)	NC score	0.053198 (rank : 386)
Query Neighborhood Hits	165	Target Neighborhood Hits	374	Shared Neighborhood Hits	43
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

DLL1_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.070821 (rank : 267)
Query Neighborhood Hits	165	Target Neighborhood Hits	455	Shared Neighborhood Hits	49
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DLL3_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.058002 (rank : 362)
Query Neighborhood Hits	165	Target Neighborhood Hits	419	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DLL3_MOUSE
θ value	θ > 10 (rank : 255)	NC score	0.057903 (rank : 365)
Query Neighborhood Hits	165	Target Neighborhood Hits	399	Shared Neighborhood Hits	45
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

DLL4_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.066994 (rank : 293)
Query Neighborhood Hits	165	Target Neighborhood Hits	435	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL4_MOUSE
θ value	θ > 10 (rank : 257)	NC score	0.063818 (rank : 319)
Query Neighborhood Hits	165	Target Neighborhood Hits	440	Shared Neighborhood Hits	49
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DNER_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.062022 (rank : 335)
Query Neighborhood Hits	165	Target Neighborhood Hits	460	Shared Neighborhood Hits	45
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DNER_MOUSE
θ value	θ > 10 (rank : 259)	NC score	0.055470 (rank : 375)
Query Neighborhood Hits	165	Target Neighborhood Hits	413	Shared Neighborhood Hits	45
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

EGFL9_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.051135 (rank : 403)
Query Neighborhood Hits	165	Target Neighborhood Hits	365	Shared Neighborhood Hits	42
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGF_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.057983 (rank : 363)
Query Neighborhood Hits	165	Target Neighborhood Hits	343	Shared Neighborhood Hits	30
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EGF_MOUSE
θ value	θ > 10 (rank : 262)	NC score	0.056756 (rank : 370)
Query Neighborhood Hits	165	Target Neighborhood Hits	358	Shared Neighborhood Hits	30
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

ELTD1_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.142614 (rank : 103)
Query Neighborhood Hits	165	Target Neighborhood Hits	269	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

ELTD1_MOUSE
θ value	θ > 10 (rank : 264)	NC score	0.131468 (rank : 113)
Query Neighborhood Hits	165	Target Neighborhood Hits	288	Shared Neighborhood Hits	23
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

EMR1_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.123105 (rank : 122)
Query Neighborhood Hits	165	Target Neighborhood Hits	382	Shared Neighborhood Hits	36
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EMR1_MOUSE
θ value	θ > 10 (rank : 266)	NC score	0.127060 (rank : 119)
Query Neighborhood Hits	165	Target Neighborhood Hits	349	Shared Neighborhood Hits	33
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EMR2_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.117358 (rank : 127)
Query Neighborhood Hits	165	Target Neighborhood Hits	345	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

EMR3_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.110705 (rank : 135)
Query Neighborhood Hits	165	Target Neighborhood Hits	245	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

EMR4_MOUSE
θ value	θ > 10 (rank : 269)	NC score	0.121511 (rank : 123)
Query Neighborhood Hits	165	Target Neighborhood Hits	191	Shared Neighborhood Hits	13
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

FBLN1_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.066535 (rank : 298)
Query Neighborhood Hits	165	Target Neighborhood Hits	324	Shared Neighborhood Hits	29
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN1_MOUSE
θ value	θ > 10 (rank : 271)	NC score	0.065390 (rank : 306)
Query Neighborhood Hits	165	Target Neighborhood Hits	329	Shared Neighborhood Hits	32
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN2_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.062177 (rank : 334)
Query Neighborhood Hits	165	Target Neighborhood Hits	392	Shared Neighborhood Hits	29
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_MOUSE
θ value	θ > 10 (rank : 273)	NC score	0.064425 (rank : 314)
Query Neighborhood Hits	165	Target Neighborhood Hits	505	Shared Neighborhood Hits	36
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN3_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.066109 (rank : 302)
Query Neighborhood Hits	165	Target Neighborhood Hits	293	Shared Neighborhood Hits	29
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN3_MOUSE
θ value	θ > 10 (rank : 275)	NC score	0.060804 (rank : 345)
Query Neighborhood Hits	165	Target Neighborhood Hits	279	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN4_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.061972 (rank : 337)
Query Neighborhood Hits	165	Target Neighborhood Hits	278	Shared Neighborhood Hits	26
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	θ > 10 (rank : 277)	NC score	0.065209 (rank : 308)
Query Neighborhood Hits	165	Target Neighborhood Hits	270	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.063201 (rank : 321)
Query Neighborhood Hits	165	Target Neighborhood Hits	329	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
θ value	θ > 10 (rank : 279)	NC score	0.060322 (rank : 352)
Query Neighborhood Hits	165	Target Neighborhood Hits	317	Shared Neighborhood Hits	31
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBN1_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.072537 (rank : 257)
Query Neighborhood Hits	165	Target Neighborhood Hits	557	Shared Neighborhood Hits	51
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.069854 (rank : 271)
Query Neighborhood Hits	165	Target Neighborhood Hits	563	Shared Neighborhood Hits	50
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.069428 (rank : 275)
Query Neighborhood Hits	165	Target Neighborhood Hits	560	Shared Neighborhood Hits	52
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
θ value	θ > 10 (rank : 283)	NC score	0.069666 (rank : 273)
Query Neighborhood Hits	165	Target Neighborhood Hits	549	Shared Neighborhood Hits	53
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.069375 (rank : 277)
Query Neighborhood Hits	165	Target Neighborhood Hits	543	Shared Neighborhood Hits	47
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FSTL4_HUMAN
θ value	θ > 10 (rank : 285)	NC score	0.052340 (rank : 394)
Query Neighborhood Hits	165	Target Neighborhood Hits	344	Shared Neighborhood Hits	18
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

FSTL5_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.050389 (rank : 408)
Query Neighborhood Hits	165	Target Neighborhood Hits	347	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

G7C_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.050871 (rank : 405)
Query Neighborhood Hits	165	Target Neighborhood Hits	21	Shared Neighborhood Hits	1
SwissProt Accessions	Q9Y334, Q5SSR5, Q96QC8, Q9UMP9	Gene names	C6orf27, G7C, NG37
Domain Architecture	No domain graphic available
Description	Protein G7c precursor.

G7C_MOUSE
θ value	θ > 10 (rank : 288)	NC score	0.052147 (rank : 398)
Query Neighborhood Hits	165	Target Neighborhood Hits	7	Shared Neighborhood Hits	1
SwissProt Accessions	Q9JHA8, Q9Z1Q8	Gene names	D17H6S56E-3, G7c
Domain Architecture	No domain graphic available
Description	Protein G7c precursor.

GP110_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.119560 (rank : 124)
Query Neighborhood Hits	165	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	Q5T601, Q5KU15, Q5T5Z9, Q86SM1, Q8IXE3, Q8IZF8, Q96DQ1	Gene names	GPR110, PGR19
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 110 precursor (G-protein coupled receptor PGR19) (G-protein coupled receptor KPG_012).

GP110_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.113333 (rank : 129)
Query Neighborhood Hits	165	Target Neighborhood Hits	92	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VEC3, Q8BMV8	Gene names	Gpr110
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 110 precursor.

GP111_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.096352 (rank : 173)
Query Neighborhood Hits	165	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IZF7, Q86SL6, Q8NGU5, Q8TDT5	Gene names	GPR111, PGR20
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 111 (G-protein coupled receptor PGR20).

GP112_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.095936 (rank : 177)
Query Neighborhood Hits	165	Target Neighborhood Hits	441	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

GP113_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.135045 (rank : 111)
Query Neighborhood Hits	165	Target Neighborhood Hits	102	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IZF5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3	Gene names	GPR113, PGR23
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 113 precursor (G-protein coupled receptor PGR23).

GP114_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.089470 (rank : 196)
Query Neighborhood Hits	165	Target Neighborhood Hits	75	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZF4, Q6ZMH7, Q6ZML4, Q86SL8, Q8IZ14	Gene names	GPR114, PGR27
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 114 precursor (G-protein coupled receptor PGR27).

GP115_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.109882 (rank : 136)
Query Neighborhood Hits	165	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZF3, Q5T5B5, Q5T5B6, Q86SN9, Q8IXE6	Gene names	GPR115, PGR18
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 (G-protein coupled receptor PGR18).

GP115_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.106187 (rank : 145)
Query Neighborhood Hits	165	Target Neighborhood Hits	69	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D2L6	Gene names	Gpr115
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 precursor.

GP116_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.123624 (rank : 121)
Query Neighborhood Hits	165	Target Neighborhood Hits	167	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

GP123_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.079973 (rank : 224)
Query Neighborhood Hits	165	Target Neighborhood Hits	120	Shared Neighborhood Hits	7
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

GP124_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.052273 (rank : 395)
Query Neighborhood Hits	165	Target Neighborhood Hits	423	Shared Neighborhood Hits	11
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GP125_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.063049 (rank : 324)
Query Neighborhood Hits	165	Target Neighborhood Hits	327	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

GP125_MOUSE
θ value	θ > 10 (rank : 301)	NC score	0.057420 (rank : 367)
Query Neighborhood Hits	165	Target Neighborhood Hits	329	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

GP126_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.090853 (rank : 192)
Query Neighborhood Hits	165	Target Neighborhood Hits	187	Shared Neighborhood Hits	9
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

GP128_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.112235 (rank : 132)
Query Neighborhood Hits	165	Target Neighborhood Hits	135	Shared Neighborhood Hits	10
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

GP128_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.096228 (rank : 174)
Query Neighborhood Hits	165	Target Neighborhood Hits	141	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BM96, Q80T42	Gene names	Gpr128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

GP133_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.116065 (rank : 128)
Query Neighborhood Hits	165	Target Neighborhood Hits	115	Shared Neighborhood Hits	7
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

GP144_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.099999 (rank : 163)
Query Neighborhood Hits	165	Target Neighborhood Hits	108	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

GPR56_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.083155 (rank : 217)
Query Neighborhood Hits	165	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y653, O95966, Q8NGB3, Q96HB4	Gene names	GPR56, TM7LN4, TM7XN1
Domain Architecture
Description	G-protein coupled receptor 56 precursor (TM7XN1 protein).

GPR56_MOUSE
θ value	θ > 10 (rank : 308)	NC score	0.077618 (rank : 232)
Query Neighborhood Hits	165	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K209, Q3UR17, Q9QZT2	Gene names	Gpr56, Cyt28
Domain Architecture
Description	G-protein coupled receptor 56 precursor (Serpentine receptor cyt28).

GPR64_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.099886 (rank : 164)
Query Neighborhood Hits	165	Target Neighborhood Hits	207	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

GPR64_MOUSE
θ value	θ > 10 (rank : 310)	NC score	0.100090 (rank : 162)
Query Neighborhood Hits	165	Target Neighborhood Hits	156	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

GPR97_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.103460 (rank : 150)
Query Neighborhood Hits	165	Target Neighborhood Hits	86	Shared Neighborhood Hits	6
SwissProt Accessions	Q86Y34, Q6ZMF4, Q86SL9, Q8IZF1	Gene names	GPR97, PGR26
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor (G-protein coupled receptor PGR26).

GPR97_MOUSE
θ value	θ > 10 (rank : 312)	NC score	0.107200 (rank : 143)
Query Neighborhood Hits	165	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R0T6	Gene names	Gpr97
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor.

GPR98_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.073624 (rank : 249)
Query Neighborhood Hits	165	Target Neighborhood Hits	202	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

GPR98_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.075897 (rank : 238)
Query Neighborhood Hits	165	Target Neighborhood Hits	206	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

GRN_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.051552 (rank : 400)
Query Neighborhood Hits	165	Target Neighborhood Hits	268	Shared Neighborhood Hits	29
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

GRN_MOUSE
θ value	θ > 10 (rank : 316)	NC score	0.053288 (rank : 385)
Query Neighborhood Hits	165	Target Neighborhood Hits	248	Shared Neighborhood Hits	29
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

JAG1_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.070067 (rank : 269)
Query Neighborhood Hits	165	Target Neighborhood Hits	514	Shared Neighborhood Hits	48
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
θ value	θ > 10 (rank : 318)	NC score	0.068365 (rank : 283)
Query Neighborhood Hits	165	Target Neighborhood Hits	518	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG2_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.068431 (rank : 281)
Query Neighborhood Hits	165	Target Neighborhood Hits	491	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG2_MOUSE
θ value	θ > 10 (rank : 320)	NC score	0.066388 (rank : 300)
Query Neighborhood Hits	165	Target Neighborhood Hits	504	Shared Neighborhood Hits	48
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

KR102_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.094983 (rank : 178)
Query Neighborhood Hits	165	Target Neighborhood Hits	264	Shared Neighborhood Hits	42
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR104_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.104350 (rank : 148)
Query Neighborhood Hits	165	Target Neighborhood Hits	313	Shared Neighborhood Hits	37
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR105_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.073512 (rank : 250)
Query Neighborhood Hits	165	Target Neighborhood Hits	271	Shared Neighborhood Hits	32
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR108_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.061095 (rank : 344)
Query Neighborhood Hits	165	Target Neighborhood Hits	226	Shared Neighborhood Hits	34
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR109_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.066429 (rank : 299)
Query Neighborhood Hits	165	Target Neighborhood Hits	226	Shared Neighborhood Hits	32
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR10A_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.054697 (rank : 377)
Query Neighborhood Hits	165	Target Neighborhood Hits	232	Shared Neighborhood Hits	29
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

KR10B_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.060288 (rank : 353)
Query Neighborhood Hits	165	Target Neighborhood Hits	269	Shared Neighborhood Hits	37
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KR10C_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.052982 (rank : 388)
Query Neighborhood Hits	165	Target Neighborhood Hits	219	Shared Neighborhood Hits	30
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KR410_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.050411 (rank : 407)
Query Neighborhood Hits	165	Target Neighborhood Hits	156	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

KR412_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.077185 (rank : 233)
Query Neighborhood Hits	165	Target Neighborhood Hits	178	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR414_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.082158 (rank : 221)
Query Neighborhood Hits	165	Target Neighborhood Hits	199	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KRA13_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.067936 (rank : 287)
Query Neighborhood Hits	165	Target Neighborhood Hits	144	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

KRA15_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.073216 (rank : 253)
Query Neighborhood Hits	165	Target Neighborhood Hits	126	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KRA42_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.053889 (rank : 383)
Query Neighborhood Hits	165	Target Neighborhood Hits	149	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

KRA45_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.058334 (rank : 360)
Query Neighborhood Hits	165	Target Neighborhood Hits	194	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

KRA47_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.063429 (rank : 320)
Query Neighborhood Hits	165	Target Neighborhood Hits	204	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KRA52_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.051914 (rank : 399)
Query Neighborhood Hits	165	Target Neighborhood Hits	236	Shared Neighborhood Hits	27
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KRA53_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.060384 (rank : 351)
Query Neighborhood Hits	165	Target Neighborhood Hits	331	Shared Neighborhood Hits	39
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA54_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.054273 (rank : 380)
Query Neighborhood Hits	165	Target Neighborhood Hits	270	Shared Neighborhood Hits	30
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA55_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.052440 (rank : 393)
Query Neighborhood Hits	165	Target Neighborhood Hits	257	Shared Neighborhood Hits	32
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA57_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.051107 (rank : 404)
Query Neighborhood Hits	165	Target Neighborhood Hits	269	Shared Neighborhood Hits	27
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA58_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.062744 (rank : 328)
Query Neighborhood Hits	165	Target Neighborhood Hits	324	Shared Neighborhood Hits	32
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA59_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.067324 (rank : 292)
Query Neighborhood Hits	165	Target Neighborhood Hits	310	Shared Neighborhood Hits	35
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KRA93_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.066853 (rank : 294)
Query Neighborhood Hits	165	Target Neighborhood Hits	203	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA98_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.083854 (rank : 215)
Query Neighborhood Hits	165	Target Neighborhood Hits	185	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA99_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.052725 (rank : 390)
Query Neighborhood Hits	165	Target Neighborhood Hits	173	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

LCE1E_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.052268 (rank : 396)
Query Neighborhood Hits	165	Target Neighborhood Hits	53	Shared Neighborhood Hits	10
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LCE1F_HUMAN
θ value	θ > 10 (rank : 348)	NC score	0.051190 (rank : 401)
Query Neighborhood Hits	165	Target Neighborhood Hits	48	Shared Neighborhood Hits	8
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LDLR_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.064677 (rank : 312)
Query Neighborhood Hits	165	Target Neighborhood Hits	375	Shared Neighborhood Hits	39
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LDLR_MOUSE
θ value	θ > 10 (rank : 350)	NC score	0.063970 (rank : 317)
Query Neighborhood Hits	165	Target Neighborhood Hits	382	Shared Neighborhood Hits	41
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LPHN1_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.103458 (rank : 151)
Query Neighborhood Hits	165	Target Neighborhood Hits	155	Shared Neighborhood Hits	6
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

LPHN2_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.102273 (rank : 152)
Query Neighborhood Hits	165	Target Neighborhood Hits	136	Shared Neighborhood Hits	6
SwissProt Accessions	O95490, O94882, Q5VX76, Q9UKY5, Q9UKY6	Gene names	LPHN2, KIAA0786, LEC1, LPHH1
Domain Architecture
Description	Latrophilin-2 precursor (Calcium-independent alpha-latrotoxin receptor 2) (Latrophilin homolog 1) (Lectomedin-1).

LPHN3_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.106004 (rank : 146)
Query Neighborhood Hits	165	Target Neighborhood Hits	139	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

LRP1B_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.064461 (rank : 313)
Query Neighborhood Hits	165	Target Neighborhood Hits	602	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1B_MOUSE
θ value	θ > 10 (rank : 355)	NC score	0.061952 (rank : 338)
Query Neighborhood Hits	165	Target Neighborhood Hits	606	Shared Neighborhood Hits	56
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.064422 (rank : 315)
Query Neighborhood Hits	165	Target Neighborhood Hits	617	Shared Neighborhood Hits	61
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP2_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.073191 (rank : 254)
Query Neighborhood Hits	165	Target Neighborhood Hits	573	Shared Neighborhood Hits	53
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LRP4_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.062550 (rank : 330)
Query Neighborhood Hits	165	Target Neighborhood Hits	355	Shared Neighborhood Hits	37
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP4_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.061359 (rank : 342)
Query Neighborhood Hits	165	Target Neighborhood Hits	351	Shared Neighborhood Hits	39
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LRP8_MOUSE
θ value	θ > 10 (rank : 360)	NC score	0.069426 (rank : 276)
Query Neighborhood Hits	165	Target Neighborhood Hits	385	Shared Neighborhood Hits	39
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LTB1L_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.064888 (rank : 311)
Query Neighborhood Hits	165	Target Neighborhood Hits	553	Shared Neighborhood Hits	49
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.061976 (rank : 336)
Query Neighborhood Hits	165	Target Neighborhood Hits	514	Shared Neighborhood Hits	47
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.062921 (rank : 326)
Query Neighborhood Hits	165	Target Neighborhood Hits	502	Shared Neighborhood Hits	44
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	θ > 10 (rank : 364)	NC score	0.060080 (rank : 355)
Query Neighborhood Hits	165	Target Neighborhood Hits	479	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP2_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.067999 (rank : 286)
Query Neighborhood Hits	165	Target Neighborhood Hits	552	Shared Neighborhood Hits	50
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP2_MOUSE
θ value	θ > 10 (rank : 366)	NC score	0.065572 (rank : 304)
Query Neighborhood Hits	165	Target Neighborhood Hits	617	Shared Neighborhood Hits	52
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP3_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.065344 (rank : 307)
Query Neighborhood Hits	165	Target Neighborhood Hits	502	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP3_MOUSE
θ value	θ > 10 (rank : 368)	NC score	0.065898 (rank : 303)
Query Neighborhood Hits	165	Target Neighborhood Hits	475	Shared Neighborhood Hits	44
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP4_MOUSE
θ value	θ > 10 (rank : 369)	NC score	0.073893 (rank : 248)
Query Neighborhood Hits	165	Target Neighborhood Hits	607	Shared Neighborhood Hits	53
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

MEGF8_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.061142 (rank : 343)
Query Neighborhood Hits	165	Target Neighborhood Hits	528	Shared Neighborhood Hits	46
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_MOUSE
θ value	θ > 10 (rank : 371)	NC score	0.057255 (rank : 368)
Query Neighborhood Hits	165	Target Neighborhood Hits	520	Shared Neighborhood Hits	46
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MUC2_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.057759 (rank : 366)
Query Neighborhood Hits	165	Target Neighborhood Hits	906	Shared Neighborhood Hits	43
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MUC5B_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.072086 (rank : 261)
Query Neighborhood Hits	165	Target Neighborhood Hits	1020	Shared Neighborhood Hits	56
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NELL1_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.087832 (rank : 200)
Query Neighborhood Hits	165	Target Neighborhood Hits	451	Shared Neighborhood Hits	40
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NELL2_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.080366 (rank : 223)
Query Neighborhood Hits	165	Target Neighborhood Hits	449	Shared Neighborhood Hits	37
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
θ value	θ > 10 (rank : 376)	NC score	0.086655 (rank : 206)
Query Neighborhood Hits	165	Target Neighborhood Hits	436	Shared Neighborhood Hits	36
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NID1_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.066673 (rank : 297)
Query Neighborhood Hits	165	Target Neighborhood Hits	329	Shared Neighborhood Hits	29
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_MOUSE
θ value	θ > 10 (rank : 378)	NC score	0.065112 (rank : 309)
Query Neighborhood Hits	165	Target Neighborhood Hits	335	Shared Neighborhood Hits	29
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.062985 (rank : 325)
Query Neighborhood Hits	165	Target Neighborhood Hits	456	Shared Neighborhood Hits	43
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID2_MOUSE
θ value	θ > 10 (rank : 380)	NC score	0.058947 (rank : 358)
Query Neighborhood Hits	165	Target Neighborhood Hits	338	Shared Neighborhood Hits	29
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NOTC1_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.073390 (rank : 252)
Query Neighborhood Hits	165	Target Neighborhood Hits	906	Shared Neighborhood Hits	63
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC1_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.072483 (rank : 260)
Query Neighborhood Hits	165	Target Neighborhood Hits	916	Shared Neighborhood Hits	59
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.071260 (rank : 265)
Query Neighborhood Hits	165	Target Neighborhood Hits	1113	Shared Neighborhood Hits	72
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
θ value	θ > 10 (rank : 384)	NC score	0.070030 (rank : 270)
Query Neighborhood Hits	165	Target Neighborhood Hits	1069	Shared Neighborhood Hits	57
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOV_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.101080 (rank : 158)
Query Neighborhood Hits	165	Target Neighborhood Hits	128	Shared Neighborhood Hits	48
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

NOV_MOUSE
θ value	θ > 10 (rank : 386)	NC score	0.098252 (rank : 167)
Query Neighborhood Hits	165	Target Neighborhood Hits	130	Shared Neighborhood Hits	48
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

PCSK5_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.063178 (rank : 323)
Query Neighborhood Hits	165	Target Neighborhood Hits	291	Shared Neighborhood Hits	46
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

PERF_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.062829 (rank : 327)
Query Neighborhood Hits	165	Target Neighborhood Hits	48	Shared Neighborhood Hits	12
SwissProt Accessions	P14222, Q86WX7	Gene names	PRF1, PFP
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (PFP) (Cytolysin).

PROS_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.050860 (rank : 406)
Query Neighborhood Hits	165	Target Neighborhood Hits	340	Shared Neighborhood Hits	26
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.051169 (rank : 402)
Query Neighborhood Hits	165	Target Neighborhood Hits	330	Shared Neighborhood Hits	26
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PUNC_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.054399 (rank : 379)
Query Neighborhood Hits	165	Target Neighborhood Hits	449	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

ROBO1_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.061557 (rank : 341)
Query Neighborhood Hits	165	Target Neighborhood Hits	529	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

ROBO1_MOUSE
θ value	θ > 10 (rank : 393)	NC score	0.060650 (rank : 347)
Query Neighborhood Hits	165	Target Neighborhood Hits	559	Shared Neighborhood Hits	17
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

ROBO2_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.061907 (rank : 339)
Query Neighborhood Hits	165	Target Neighborhood Hits	479	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HCK4, O43608	Gene names	ROBO2, KIAA1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

ROBO2_MOUSE
θ value	θ > 10 (rank : 395)	NC score	0.062517 (rank : 332)
Query Neighborhood Hits	165	Target Neighborhood Hits	504	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

ROBO3_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.062569 (rank : 329)
Query Neighborhood Hits	165	Target Neighborhood Hits	570	Shared Neighborhood Hits	22
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

ROBO3_MOUSE
θ value	θ > 10 (rank : 397)	NC score	0.060787 (rank : 346)
Query Neighborhood Hits	165	Target Neighborhood Hits	524	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

ROBO4_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.076150 (rank : 237)
Query Neighborhood Hits	165	Target Neighborhood Hits	364	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

ROBO4_MOUSE
θ value	θ > 10 (rank : 399)	NC score	0.078588 (rank : 229)
Query Neighborhood Hits	165	Target Neighborhood Hits	358	Shared Neighborhood Hits	18
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

SCUB3_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.059195 (rank : 357)
Query Neighborhood Hits	165	Target Neighborhood Hits	428	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
θ value	θ > 10 (rank : 401)	NC score	0.060538 (rank : 349)
Query Neighborhood Hits	165	Target Neighborhood Hits	442	Shared Neighborhood Hits	40
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SEM3A_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.087874 (rank : 199)
Query Neighborhood Hits	165	Target Neighborhood Hits	78	Shared Neighborhood Hits	6
SwissProt Accessions	Q14563	Gene names	SEMA3A
Domain Architecture
Description	Semaphorin-3A precursor (Semaphorin III) (Sema III).

SEM3A_MOUSE
θ value	θ > 10 (rank : 403)	NC score	0.086750 (rank : 205)
Query Neighborhood Hits	165	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	O08665, Q5BL08, Q62180, Q62215	Gene names	Sema3a, Semad, SemD
Domain Architecture
Description	Semaphorin-3A precursor (Semaphorin III) (Sema III) (Semaphorin D) (Sema D).

SEM3B_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.087816 (rank : 201)
Query Neighborhood Hits	165	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	Q13214, Q8TB71, Q8TDV7, Q93018, Q96GX0	Gene names	SEMA3B, SEMA5
Domain Architecture
Description	Semaphorin-3B precursor (Semaphorin V) (Sema V) (Sema A(V)).

SEM3B_MOUSE
θ value	θ > 10 (rank : 405)	NC score	0.085733 (rank : 207)
Query Neighborhood Hits	165	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	Q62177	Gene names	Sema3b, Sema, Semaa
Domain Architecture
Description	Semaphorin-3B precursor (Semaphorin A) (Sema A).

SEM3C_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.094347 (rank : 180)
Query Neighborhood Hits	165	Target Neighborhood Hits	106	Shared Neighborhood Hits	10
SwissProt Accessions	Q99985	Gene names	SEMA3C, SEMAE
Domain Architecture
Description	Semaphorin-3C precursor (Semaphorin E) (Sema E).

SEM3C_MOUSE
θ value	θ > 10 (rank : 407)	NC score	0.094279 (rank : 182)
Query Neighborhood Hits	165	Target Neighborhood Hits	113	Shared Neighborhood Hits	12
SwissProt Accessions	Q62181	Gene names	Sema3c, Semae, SemE
Domain Architecture
Description	Semaphorin-3C precursor (Semaphorin E) (Sema E).

SEM3D_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.085251 (rank : 209)
Query Neighborhood Hits	165	Target Neighborhood Hits	104	Shared Neighborhood Hits	6
SwissProt Accessions	O95025, Q6UW77, Q8NCQ1	Gene names	SEMA3D
Domain Architecture
Description	Semaphorin-3D precursor.

SEM3D_MOUSE
θ value	θ > 10 (rank : 409)	NC score	0.084607 (rank : 211)
Query Neighborhood Hits	165	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BH34	Gene names	Sema3d
Domain Architecture	No domain graphic available
Description	Semaphorin-3D precursor.

SEM3E_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.087183 (rank : 203)
Query Neighborhood Hits	165	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	O15041, Q75M94, Q75M97	Gene names	SEMA3E, KIAA0331
Domain Architecture	No domain graphic available
Description	Semaphorin-3E precursor.

SEM3E_MOUSE
θ value	θ > 10 (rank : 411)	NC score	0.087684 (rank : 202)
Query Neighborhood Hits	165	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	P70275, O09078, O09079	Gene names	Sema3e, Semah, Semh
Domain Architecture
Description	Semaphorin-3E precursor (Semaphorin H) (Sema H).

SEM3F_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.093011 (rank : 186)
Query Neighborhood Hits	165	Target Neighborhood Hits	100	Shared Neighborhood Hits	14
SwissProt Accessions	Q13275, Q13274, Q13372, Q15704	Gene names	SEMA3F
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV) (Sema III/F).

SEM3F_MOUSE
θ value	θ > 10 (rank : 413)	NC score	0.089337 (rank : 197)
Query Neighborhood Hits	165	Target Neighborhood Hits	86	Shared Neighborhood Hits	6
SwissProt Accessions	O88632, O88633	Gene names	Sema3f
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV).

SEM4A_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.094285 (rank : 181)
Query Neighborhood Hits	165	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H3S1, Q8WUA9	Gene names	SEMA4A, SEMB
Domain Architecture
Description	Semaphorin-4A precursor (Semaphorin B) (Sema B).

SEM4A_MOUSE
θ value	θ > 10 (rank : 415)	NC score	0.093283 (rank : 185)
Query Neighborhood Hits	165	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	Q62178	Gene names	Sema4a, Semab, SemB
Domain Architecture
Description	Semaphorin-4A precursor (Semaphorin B) (Sema B).

SEM4B_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.091246 (rank : 191)
Query Neighborhood Hits	165	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NPR2, Q6UXE3, Q8WVP9, Q96FK5, Q9C0B8, Q9H691, Q9NPM8, Q9NPN0	Gene names	SEMA4B, KIAA1745
Domain Architecture
Description	Semaphorin-4B precursor.

SEM4B_MOUSE
θ value	θ > 10 (rank : 417)	NC score	0.091339 (rank : 189)
Query Neighborhood Hits	165	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	Q62179, Q4PKI6, Q69ZB7	Gene names	Sema4b, Kiaa1745, Semac, SemC
Domain Architecture	No domain graphic available
Description	Semaphorin-4B precursor (Semaphorin C) (Sema C).

SEM4C_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.096188 (rank : 175)
Query Neighborhood Hits	165	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q9C0C4, Q7Z5X0	Gene names	SEMA4C, KIAA1739
Domain Architecture
Description	Semaphorin-4C precursor.

SEM4C_MOUSE
θ value	θ > 10 (rank : 419)	NC score	0.093444 (rank : 184)
Query Neighborhood Hits	165	Target Neighborhood Hits	77	Shared Neighborhood Hits	5
SwissProt Accessions	Q64151	Gene names	Sema4c, Semacl1, Semai
Domain Architecture
Description	Semaphorin-4C precursor (Semaphorin I) (Sema I) (Semaphorin C-like 1) (M-Sema F).

SEM4D_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.091296 (rank : 190)
Query Neighborhood Hits	165	Target Neighborhood Hits	139	Shared Neighborhood Hits	7
SwissProt Accessions	Q92854, Q7Z5S4	Gene names	SEMA4D, CD100
Domain Architecture
Description	Semaphorin-4D precursor (Leukocyte activation antigen CD100) (BB18) (A8) (GR3).

SEM4D_MOUSE
θ value	θ > 10 (rank : 421)	NC score	0.090437 (rank : 193)
Query Neighborhood Hits	165	Target Neighborhood Hits	143	Shared Neighborhood Hits	10
SwissProt Accessions	O09126	Gene names	Sema4d, Semacl2, Semaj
Domain Architecture
Description	Semaphorin-4D precursor (Semaphorin J) (Sema J) (Semaphorin C-like 2) (M-Sema G).

SEM4F_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.088565 (rank : 198)
Query Neighborhood Hits	165	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	O95754, Q9NS35	Gene names	SEMA4F, SEMAM, SEMAW
Domain Architecture
Description	Semaphorin-4F precursor (Semaphorin W) (Sema W) (Semaphorin M) (Sema M).

SEM4F_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.089538 (rank : 195)
Query Neighborhood Hits	165	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z123, Q9R1Y1	Gene names	Sema4f, Semaw
Domain Architecture
Description	Semaphorin-4F precursor (Semaphorin W) (Sema W).

SEM4G_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.084139 (rank : 213)
Query Neighborhood Hits	165	Target Neighborhood Hits	88	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NTN9, Q9HCF3	Gene names	SEMA4G, KIAA1619
Domain Architecture
Description	Semaphorin-4G precursor.

SEM4G_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.085325 (rank : 208)
Query Neighborhood Hits	165	Target Neighborhood Hits	99	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WUH7	Gene names	Sema4g
Domain Architecture
Description	Semaphorin-4G precursor.

SEM6A_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.096613 (rank : 171)
Query Neighborhood Hits	165	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H2E6, Q9P2H9	Gene names	SEMA6A, KIAA1368
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1).

SEM6A_MOUSE
θ value	θ > 10 (rank : 427)	NC score	0.097237 (rank : 168)
Query Neighborhood Hits	165	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	O35464, Q6P5A8, Q6PCN9, Q9EQ71	Gene names	Sema6a, Semaq
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1) (Semaphorin Q) (Sema Q).

SEM6B_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.101096 (rank : 157)
Query Neighborhood Hits	165	Target Neighborhood Hits	187	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

SEM6B_MOUSE
θ value	θ > 10 (rank : 429)	NC score	0.101101 (rank : 156)
Query Neighborhood Hits	165	Target Neighborhood Hits	200	Shared Neighborhood Hits	12
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

SEM6C_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.100171 (rank : 161)
Query Neighborhood Hits	165	Target Neighborhood Hits	117	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H3T2, Q5JR71, Q8WXT8, Q8WXT9, Q8WXU0, Q96JF8	Gene names	SEMA6C, KIAA1869, SEMAY
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SEM6C_MOUSE
θ value	θ > 10 (rank : 431)	NC score	0.099791 (rank : 165)
Query Neighborhood Hits	165	Target Neighborhood Hits	352	Shared Neighborhood Hits	20
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SEM6D_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.096185 (rank : 176)
Query Neighborhood Hits	165	Target Neighborhood Hits	169	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFY4, Q8NFY3, Q8NFY5, Q8NFY6, Q8NFY7, Q9P249	Gene names	SEMA6D, KIAA1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

SEM6D_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.096465 (rank : 172)
Query Neighborhood Hits	165	Target Neighborhood Hits	161	Shared Neighborhood Hits	7
SwissProt Accessions	Q76KF0, Q76KF1, Q76KF2, Q76KF3, Q76KF4, Q80TD0	Gene names	Sema6d, Kiaa1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

SEM7A_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.083082 (rank : 218)
Query Neighborhood Hits	165	Target Neighborhood Hits	67	Shared Neighborhood Hits	4
SwissProt Accessions	O75326	Gene names	SEMA7A, CD108, SEMAL
Domain Architecture
Description	Semaphorin-7A precursor (Semaphorin L) (Sema L) (Semaphorin K1) (Sema K1) (John-Milton-Hargen human blood group Ag) (JMH blood group antigen) (CD108 antigen) (CDw108).

SEM7A_MOUSE
θ value	θ > 10 (rank : 435)	NC score	0.085185 (rank : 210)
Query Neighborhood Hits	165	Target Neighborhood Hits	64	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QUR8, O88371	Gene names	Sema7a, Cd108, Semal, Semk1
Domain Architecture
Description	Semaphorin-7A precursor (Semaphorin L) (Sema L) (Semaphorin K1) (Sema K1) (CD108 antigen) (CDw108).

SORL_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.058182 (rank : 361)
Query Neighborhood Hits	165	Target Neighborhood Hits	440	Shared Neighborhood Hits	41
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SORL_MOUSE
θ value	θ > 10 (rank : 437)	NC score	0.053867 (rank : 384)
Query Neighborhood Hits	165	Target Neighborhood Hits	439	Shared Neighborhood Hits	40
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

SPON2_HUMAN
θ value	θ > 10 (rank : 438)	NC score	0.220310 (rank : 76)
Query Neighborhood Hits	165	Target Neighborhood Hits	53	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BUD6, Q9ULW1	Gene names	SPON2, DIL1
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin) (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1).

SPON2_MOUSE
θ value	θ > 10 (rank : 439)	NC score	0.184389 (rank : 80)
Query Neighborhood Hits	165	Target Neighborhood Hits	42	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).

SREC2_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.060104 (rank : 354)
Query Neighborhood Hits	165	Target Neighborhood Hits	645	Shared Neighborhood Hits	53
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SREC2_MOUSE
θ value	θ > 10 (rank : 441)	NC score	0.062501 (rank : 333)
Query Neighborhood Hits	165	Target Neighborhood Hits	605	Shared Neighborhood Hits	56
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

STAB1_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.071678 (rank : 263)
Query Neighborhood Hits	165	Target Neighborhood Hits	546	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB1_MOUSE
θ value	θ > 10 (rank : 443)	NC score	0.068327 (rank : 284)
Query Neighborhood Hits	165	Target Neighborhood Hits	566	Shared Neighborhood Hits	47
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

STAB2_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.074156 (rank : 247)
Query Neighborhood Hits	165	Target Neighborhood Hits	534	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

TRBM_HUMAN
θ value	θ > 10 (rank : 445)	NC score	0.068401 (rank : 282)
Query Neighborhood Hits	165	Target Neighborhood Hits	339	Shared Neighborhood Hits	32
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRBM_MOUSE
θ value	θ > 10 (rank : 446)	NC score	0.064965 (rank : 310)
Query Neighborhood Hits	165	Target Neighborhood Hits	361	Shared Neighborhood Hits	37
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TSP3_HUMAN
θ value	θ > 10 (rank : 447)	NC score	0.161125 (rank : 85)
Query Neighborhood Hits	165	Target Neighborhood Hits	250	Shared Neighborhood Hits	23
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_MOUSE
θ value	θ > 10 (rank : 448)	NC score	0.160075 (rank : 89)
Query Neighborhood Hits	165	Target Neighborhood Hits	247	Shared Neighborhood Hits	23
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP4_HUMAN
θ value	θ > 10 (rank : 449)	NC score	0.153144 (rank : 93)
Query Neighborhood Hits	165	Target Neighborhood Hits	277	Shared Neighborhood Hits	24
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_MOUSE
θ value	θ > 10 (rank : 450)	NC score	0.152534 (rank : 94)
Query Neighborhood Hits	165	Target Neighborhood Hits	276	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

UROM_HUMAN
θ value	θ > 10 (rank : 451)	NC score	0.068045 (rank : 285)
Query Neighborhood Hits	165	Target Neighborhood Hits	284	Shared Neighborhood Hits	25
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_MOUSE
θ value	θ > 10 (rank : 452)	NC score	0.059607 (rank : 356)
Query Neighborhood Hits	165	Target Neighborhood Hits	276	Shared Neighborhood Hits	29
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

VIPR2_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.056316 (rank : 372)
Query Neighborhood Hits	165	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	P41587, Q13053, Q15870	Gene names	VIPR2, VIP2R
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) (Helodermin-preferring VIP receptor).

VIPR2_MOUSE
θ value	θ > 10 (rank : 454)	NC score	0.052182 (rank : 397)
Query Neighborhood Hits	165	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	P41588, P97750	Gene names	Vipr2
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3).

VLDLR_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.054103 (rank : 381)
Query Neighborhood Hits	165	Target Neighborhood Hits	383	Shared Neighborhood Hits	35
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
θ value	θ > 10 (rank : 456)	NC score	0.050316 (rank : 409)
Query Neighborhood Hits	165	Target Neighborhood Hits	360	Shared Neighborhood Hits	34
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VWF_HUMAN
θ value	θ > 10 (rank : 457)	NC score	0.091684 (rank : 188)
Query Neighborhood Hits	165	Target Neighborhood Hits	396	Shared Neighborhood Hits	49
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

VWF_MOUSE
θ value	θ > 10 (rank : 458)	NC score	0.074374 (rank : 244)
Query Neighborhood Hits	165	Target Neighborhood Hits	381	Shared Neighborhood Hits	41
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

WISP1_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.128069 (rank : 118)
Query Neighborhood Hits	165	Target Neighborhood Hits	121	Shared Neighborhood Hits	55
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

WISP1_MOUSE
θ value	θ > 10 (rank : 460)	NC score	0.136068 (rank : 107)
Query Neighborhood Hits	165	Target Neighborhood Hits	123	Shared Neighborhood Hits	51
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

WISP3_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.079740 (rank : 225)
Query Neighborhood Hits	165	Target Neighborhood Hits	87	Shared Neighborhood Hits	37
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

ZAN_HUMAN
θ value	θ > 10 (rank : 462)	NC score	0.058596 (rank : 359)
Query Neighborhood Hits	165	Target Neighborhood Hits	679	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ZAN_MOUSE
θ value	θ > 10 (rank : 463)	NC score	0.097061 (rank : 169)
Query Neighborhood Hits	165	Target Neighborhood Hits	808	Shared Neighborhood Hits	70
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

ZO1_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.057184 (rank : 369)
Query Neighborhood Hits	165	Target Neighborhood Hits	474	Shared Neighborhood Hits	14
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO1_MOUSE
θ value	θ > 10 (rank : 465)	NC score	0.056498 (rank : 371)
Query Neighborhood Hits	165	Target Neighborhood Hits	453	Shared Neighborhood Hits	10
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

Hits sorted by NC score

PROP_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	165	Target Neighborhood Hits	165	Shared Neighborhood Hits	165
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

PROP_HUMAN
NC score	0.985873 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	165	Target Neighborhood Hits	126	Shared Neighborhood Hits	95
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

SPON1_MOUSE
NC score	0.805614 (rank : 3)	θ value	1.99067e-23 (rank : 19)
Query Neighborhood Hits	165	Target Neighborhood Hits	123	Shared Neighborhood Hits	91
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

SPON1_HUMAN
NC score	0.803740 (rank : 4)	θ value	7.56453e-23 (rank : 20)
Query Neighborhood Hits	165	Target Neighborhood Hits	117	Shared Neighborhood Hits	89
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

BAI3_MOUSE
NC score	0.728258 (rank : 5)	θ value	2.1121e-49 (rank : 5)
Query Neighborhood Hits	165	Target Neighborhood Hits	250	Shared Neighborhood Hits	90
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_HUMAN
NC score	0.725544 (rank : 6)	θ value	7.25919e-50 (rank : 4)
Query Neighborhood Hits	165	Target Neighborhood Hits	246	Shared Neighborhood Hits	90
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI1_MOUSE
NC score	0.718006 (rank : 7)	θ value	2.41655e-45 (rank : 7)
Query Neighborhood Hits	165	Target Neighborhood Hits	340	Shared Neighborhood Hits	89
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_HUMAN
NC score	0.716772 (rank : 8)	θ value	7.03111e-45 (rank : 9)
Query Neighborhood Hits	165	Target Neighborhood Hits	375	Shared Neighborhood Hits	93
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

UNC5A_MOUSE
NC score	0.716177 (rank : 9)	θ value	6.62687e-19 (rank : 25)
Query Neighborhood Hits	165	Target Neighborhood Hits	203	Shared Neighborhood Hits	75
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

BAI2_HUMAN
NC score	0.715344 (rank : 10)	θ value	1.79215e-40 (rank : 15)
Query Neighborhood Hits	165	Target Neighborhood Hits	332	Shared Neighborhood Hits	92
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

UNC5B_MOUSE
NC score	0.714746 (rank : 11)	θ value	7.56453e-23 (rank : 21)
Query Neighborhood Hits	165	Target Neighborhood Hits	226	Shared Neighborhood Hits	78
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

BAI2_MOUSE
NC score	0.714118 (rank : 12)	θ value	2.11701e-41 (rank : 14)
Query Neighborhood Hits	165	Target Neighborhood Hits	323	Shared Neighborhood Hits	93
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

UNC5B_HUMAN
NC score	0.712429 (rank : 13)	θ value	9.87957e-23 (rank : 22)
Query Neighborhood Hits	165	Target Neighborhood Hits	225	Shared Neighborhood Hits	78
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5C_MOUSE
NC score	0.694799 (rank : 14)	θ value	7.82807e-20 (rank : 23)
Query Neighborhood Hits	165	Target Neighborhood Hits	225	Shared Neighborhood Hits	77
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

UNC5C_HUMAN
NC score	0.694777 (rank : 15)	θ value	2.97466e-19 (rank : 24)
Query Neighborhood Hits	165	Target Neighborhood Hits	226	Shared Neighborhood Hits	77
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

TSP2_MOUSE
NC score	0.690008 (rank : 16)	θ value	1.6774e-38 (rank : 17)
Query Neighborhood Hits	165	Target Neighborhood Hits	352	Shared Neighborhood Hits	106
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

ATL2_MOUSE
NC score	0.688126 (rank : 17)	θ value	5.62301e-10 (rank : 48)
Query Neighborhood Hits	165	Target Neighborhood Hits	137	Shared Neighborhood Hits	83
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

TSP2_HUMAN
NC score	0.687323 (rank : 18)	θ value	1.51715e-39 (rank : 16)
Query Neighborhood Hits	165	Target Neighborhood Hits	359	Shared Neighborhood Hits	109
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

ATL2_HUMAN
NC score	0.686591 (rank : 19)	θ value	1.25267e-09 (rank : 51)
Query Neighborhood Hits	165	Target Neighborhood Hits	125	Shared Neighborhood Hits	82
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

TSP1_MOUSE
NC score	0.676970 (rank : 20)	θ value	4.2656e-42 (rank : 12)
Query Neighborhood Hits	165	Target Neighborhood Hits	396	Shared Neighborhood Hits	107
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_HUMAN
NC score	0.676954 (rank : 21)	θ value	1.2411e-41 (rank : 13)
Query Neighborhood Hits	165	Target Neighborhood Hits	389	Shared Neighborhood Hits	109
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

UNC5D_HUMAN
NC score	0.674283 (rank : 22)	θ value	1.92812e-18 (rank : 26)
Query Neighborhood Hits	165	Target Neighborhood Hits	267	Shared Neighborhood Hits	79
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5D_MOUSE
NC score	0.671507 (rank : 23)	θ value	2.5182e-18 (rank : 27)
Query Neighborhood Hits	165	Target Neighborhood Hits	268	Shared Neighborhood Hits	79
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

ATS9_HUMAN
NC score	0.659662 (rank : 24)	θ value	1.24977e-17 (rank : 28)
Query Neighborhood Hits	165	Target Neighborhood Hits	219	Shared Neighborhood Hits	96
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

ATS13_HUMAN
NC score	0.658576 (rank : 25)	θ value	6.21693e-09 (rank : 54)
Query Neighborhood Hits	165	Target Neighborhood Hits	238	Shared Neighborhood Hits	88
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS13_MOUSE
NC score	0.651956 (rank : 26)	θ value	8.11959e-09 (rank : 56)
Query Neighborhood Hits	165	Target Neighborhood Hits	227	Shared Neighborhood Hits	87
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS18_MOUSE
NC score	0.650907 (rank : 27)	θ value	8.38298e-14 (rank : 34)
Query Neighborhood Hits	165	Target Neighborhood Hits	163	Shared Neighborhood Hits	84
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS16_MOUSE
NC score	0.649574 (rank : 28)	θ value	2.60593e-15 (rank : 29)
Query Neighborhood Hits	165	Target Neighborhood Hits	179	Shared Neighborhood Hits	91
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS20_MOUSE
NC score	0.649002 (rank : 29)	θ value	7.58209e-15 (rank : 31)
Query Neighborhood Hits	165	Target Neighborhood Hits	225	Shared Neighborhood Hits	95
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS16_HUMAN
NC score	0.646919 (rank : 30)	θ value	4.91457e-14 (rank : 33)
Query Neighborhood Hits	165	Target Neighborhood Hits	208	Shared Neighborhood Hits	94
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS18_HUMAN
NC score	0.642579 (rank : 31)	θ value	3.52202e-12 (rank : 36)
Query Neighborhood Hits	165	Target Neighborhood Hits	169	Shared Neighborhood Hits	86
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS8_MOUSE
NC score	0.641476 (rank : 32)	θ value	7.09661e-13 (rank : 35)
Query Neighborhood Hits	165	Target Neighborhood Hits	139	Shared Neighborhood Hits	80
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

ATS17_HUMAN
NC score	0.639190 (rank : 33)	θ value	2.52405e-10 (rank : 47)
Query Neighborhood Hits	165	Target Neighborhood Hits	194	Shared Neighborhood Hits	90
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

ATS20_HUMAN
NC score	0.638147 (rank : 34)	θ value	4.44505e-15 (rank : 30)
Query Neighborhood Hits	165	Target Neighborhood Hits	192	Shared Neighborhood Hits	92
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS4_HUMAN
NC score	0.636411 (rank : 35)	θ value	3.52202e-12 (rank : 37)
Query Neighborhood Hits	165	Target Neighborhood Hits	138	Shared Neighborhood Hits	77
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

ATS4_MOUSE
NC score	0.635819 (rank : 36)	θ value	3.52202e-12 (rank : 38)
Query Neighborhood Hits	165	Target Neighborhood Hits	145	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

ATS8_HUMAN
NC score	0.633687 (rank : 37)	θ value	2.98157e-11 (rank : 43)
Query Neighborhood Hits	165	Target Neighborhood Hits	145	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

ATS2_HUMAN
NC score	0.632383 (rank : 38)	θ value	1.133e-10 (rank : 44)
Query Neighborhood Hits	165	Target Neighborhood Hits	179	Shared Neighborhood Hits	83
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATL5_HUMAN
NC score	0.629272 (rank : 39)	θ value	0.00020696 (rank : 71)
Query Neighborhood Hits	165	Target Neighborhood Hits	103	Shared Neighborhood Hits	72
SwissProt Accessions	Q6ZMM2, Q8IW95	Gene names	ADAMTSL5, THSD6
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 5 precursor (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6).

SEM5A_HUMAN
NC score	0.628253 (rank : 40)	θ value	4.55743e-44 (rank : 11)
Query Neighborhood Hits	165	Target Neighborhood Hits	177	Shared Neighborhood Hits	87
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

ATS2_MOUSE
NC score	0.627335 (rank : 41)	θ value	8.11959e-09 (rank : 57)
Query Neighborhood Hits	165	Target Neighborhood Hits	179	Shared Neighborhood Hits	81
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

SEM5B_MOUSE
NC score	0.627233 (rank : 42)	θ value	7.51208e-47 (rank : 6)
Query Neighborhood Hits	165	Target Neighborhood Hits	190	Shared Neighborhood Hits	93
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

SEM5B_HUMAN
NC score	0.624601 (rank : 43)	θ value	1.19932e-44 (rank : 10)
Query Neighborhood Hits	165	Target Neighborhood Hits	178	Shared Neighborhood Hits	93
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

ATS12_MOUSE
NC score	0.624374 (rank : 44)	θ value	1.02475e-11 (rank : 39)
Query Neighborhood Hits	165	Target Neighborhood Hits	220	Shared Neighborhood Hits	90
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS1_MOUSE
NC score	0.624172 (rank : 45)	θ value	2.28291e-11 (rank : 41)
Query Neighborhood Hits	165	Target Neighborhood Hits	158	Shared Neighborhood Hits	83
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

SEM5A_MOUSE
NC score	0.623582 (rank : 46)	θ value	4.122e-45 (rank : 8)
Query Neighborhood Hits	165	Target Neighborhood Hits	162	Shared Neighborhood Hits	84
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

ATS14_HUMAN
NC score	0.623255 (rank : 47)	θ value	3.08544e-08 (rank : 59)
Query Neighborhood Hits	165	Target Neighborhood Hits	382	Shared Neighborhood Hits	92
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

ATS12_HUMAN
NC score	0.622381 (rank : 48)	θ value	1.33837e-11 (rank : 40)
Query Neighborhood Hits	165	Target Neighborhood Hits	251	Shared Neighborhood Hits	86
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS1_HUMAN
NC score	0.621709 (rank : 49)	θ value	1.9326e-10 (rank : 45)
Query Neighborhood Hits	165	Target Neighborhood Hits	159	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

ATL1_HUMAN
NC score	0.620948 (rank : 50)	θ value	4.1701e-05 (rank : 67)
Query Neighborhood Hits	165	Target Neighborhood Hits	93	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N6G6, Q5T708, Q96RW4, Q9BXY3	Gene names	ADAMTSL1, ADAMTSR1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (ADAMTSL-1) (Punctin-1).

ATS6_HUMAN
NC score	0.618759 (rank : 51)	θ value	2.98157e-11 (rank : 42)
Query Neighborhood Hits	165	Target Neighborhood Hits	141	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

ATL1_MOUSE
NC score	0.618039 (rank : 52)	θ value	5.44631e-05 (rank : 69)
Query Neighborhood Hits	165	Target Neighborhood Hits	80	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BLI0	Gene names	Adamtsl1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (Punctin-1).

ATS15_HUMAN
NC score	0.617585 (rank : 53)	θ value	1.63604e-09 (rank : 52)
Query Neighborhood Hits	165	Target Neighborhood Hits	151	Shared Neighborhood Hits	82
SwissProt Accessions	Q8TE58	Gene names	ADAMTS15
Domain Architecture
Description	ADAMTS-15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 15) (ADAM-TS 15) (ADAM-TS15).

ATS3_HUMAN
NC score	0.612944 (rank : 54)	θ value	1.9326e-10 (rank : 46)
Query Neighborhood Hits	165	Target Neighborhood Hits	179	Shared Neighborhood Hits	87
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS7_HUMAN
NC score	0.609361 (rank : 55)	θ value	8.11959e-09 (rank : 58)
Query Neighborhood Hits	165	Target Neighborhood Hits	169	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

ATS19_MOUSE
NC score	0.606558 (rank : 56)	θ value	7.34386e-10 (rank : 49)
Query Neighborhood Hits	165	Target Neighborhood Hits	188	Shared Neighborhood Hits	79
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS5_MOUSE
NC score	0.602970 (rank : 57)	θ value	4.76016e-09 (rank : 53)
Query Neighborhood Hits	165	Target Neighborhood Hits	147	Shared Neighborhood Hits	79
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

ATS19_HUMAN
NC score	0.596937 (rank : 58)	θ value	6.21693e-09 (rank : 55)
Query Neighborhood Hits	165	Target Neighborhood Hits	203	Shared Neighborhood Hits	76
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS5_HUMAN
NC score	0.592975 (rank : 59)	θ value	4.0297e-08 (rank : 61)
Query Neighborhood Hits	165	Target Neighborhood Hits	141	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

ATL3_HUMAN
NC score	0.581912 (rank : 60)	θ value	2.20605e-14 (rank : 32)
Query Neighborhood Hits	165	Target Neighborhood Hits	414	Shared Neighborhood Hits	88
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

SSPO_MOUSE
NC score	0.575057 (rank : 61)	θ value	2.26708e-35 (rank : 18)
Query Neighborhood Hits	165	Target Neighborhood Hits	800	Shared Neighborhood Hits	127
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

THSD1_HUMAN
NC score	0.571962 (rank : 62)	θ value	0.00035302 (rank : 73)
Query Neighborhood Hits	165	Target Neighborhood Hits	136	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

UNC5A_HUMAN
NC score	0.555886 (rank : 63)	θ value	0.000786445 (rank : 75)
Query Neighborhood Hits	165	Target Neighborhood Hits	198	Shared Neighborhood Hits	74
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

THSD1_MOUSE
NC score	0.553526 (rank : 64)	θ value	0.000121331 (rank : 70)
Query Neighborhood Hits	165	Target Neighborhood Hits	153	Shared Neighborhood Hits	74
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

CO8B_MOUSE
NC score	0.538585 (rank : 65)	θ value	3.08544e-08 (rank : 60)
Query Neighborhood Hits	165	Target Neighborhood Hits	224	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO6_HUMAN
NC score	0.523401 (rank : 66)	θ value	2.88788e-06 (rank : 64)
Query Neighborhood Hits	165	Target Neighborhood Hits	331	Shared Neighborhood Hits	95
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CO8B_HUMAN
NC score	0.509958 (rank : 67)	θ value	5.26297e-08 (rank : 62)
Query Neighborhood Hits	165	Target Neighborhood Hits	199	Shared Neighborhood Hits	78
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO8A_HUMAN
NC score	0.508495 (rank : 68)	θ value	9.92553e-07 (rank : 63)
Query Neighborhood Hits	165	Target Neighborhood Hits	200	Shared Neighborhood Hits	82
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CILP2_HUMAN
NC score	0.507691 (rank : 69)	θ value	9.59137e-10 (rank : 50)
Query Neighborhood Hits	165	Target Neighborhood Hits	307	Shared Neighborhood Hits	82
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

CO8A_MOUSE
NC score	0.499682 (rank : 70)	θ value	4.1701e-05 (rank : 68)
Query Neighborhood Hits	165	Target Neighborhood Hits	182	Shared Neighborhood Hits	77
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO7_HUMAN
NC score	0.480371 (rank : 71)	θ value	8.40245e-06 (rank : 65)
Query Neighborhood Hits	165	Target Neighborhood Hits	278	Shared Neighborhood Hits	81
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CI094_HUMAN
NC score	0.453166 (rank : 72)	θ value	0.0736092 (rank : 86)
Query Neighborhood Hits	165	Target Neighborhood Hits	310	Shared Neighborhood Hits	72
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

HMCN1_HUMAN
NC score	0.418548 (rank : 73)	θ value	4.38363e-63 (rank : 3)
Query Neighborhood Hits	165	Target Neighborhood Hits	983	Shared Neighborhood Hits	111
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

CILP1_MOUSE
NC score	0.398261 (rank : 74)	θ value	0.00869519 (rank : 78)
Query Neighborhood Hits	165	Target Neighborhood Hits	282	Shared Neighborhood Hits	79
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CILP1_HUMAN
NC score	0.389824 (rank : 75)	θ value	0.000270298 (rank : 72)
Query Neighborhood Hits	165	Target Neighborhood Hits	266	Shared Neighborhood Hits	83
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

SPON2_HUMAN
NC score	0.220310 (rank : 76)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	165	Target Neighborhood Hits	53	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BUD6, Q9ULW1	Gene names	SPON2, DIL1
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin) (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1).

RSPO1_HUMAN
NC score	0.216539 (rank : 77)	θ value	0.0431538 (rank : 85)
Query Neighborhood Hits	165	Target Neighborhood Hits	101	Shared Neighborhood Hits	51
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

RSPO4_MOUSE
NC score	0.197268 (rank : 78)	θ value	0.0113563 (rank : 81)
Query Neighborhood Hits	165	Target Neighborhood Hits	110	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

RSPO1_MOUSE
NC score	0.189627 (rank : 79)	θ value	0.163984 (rank : 92)
Query Neighborhood Hits	165	Target Neighborhood Hits	85	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

SPON2_MOUSE
NC score	0.184389 (rank : 80)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	165	Target Neighborhood Hits	42	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).

RSPO3_HUMAN
NC score	0.183428 (rank : 81)	θ value	0.365318 (rank : 97)
Query Neighborhood Hits	165	Target Neighborhood Hits	128	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

RSPO3_MOUSE
NC score	0.182787 (rank : 82)	θ value	0.365318 (rank : 98)
Query Neighborhood Hits	165	Target Neighborhood Hits	120	Shared Neighborhood Hits	42
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

RSPO4_HUMAN
NC score	0.169573 (rank : 83)	θ value	0.163984 (rank : 93)
Query Neighborhood Hits	165	Target Neighborhood Hits	110	Shared Neighborhood Hits	40
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

FRAS1_MOUSE
NC score	0.162521 (rank : 84)	θ value	0.0736092 (rank : 87)
Query Neighborhood Hits	165	Target Neighborhood Hits	747	Shared Neighborhood Hits	89
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

TSP3_HUMAN
NC score	0.161125 (rank : 85)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	165	Target Neighborhood Hits	250	Shared Neighborhood Hits	23
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

ADAM8_HUMAN
NC score	0.160951 (rank : 86)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	165	Target Neighborhood Hits	327	Shared Neighborhood Hits	60
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

CO9_MOUSE
NC score	0.160593 (rank : 87)	θ value	1.06291 (rank : 108)
Query Neighborhood Hits	165	Target Neighborhood Hits	153	Shared Neighborhood Hits	32
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

ADAM8_MOUSE
NC score	0.160144 (rank : 88)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	165	Target Neighborhood Hits	326	Shared Neighborhood Hits	63
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

TSP3_MOUSE
NC score	0.160075 (rank : 89)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	165	Target Neighborhood Hits	247	Shared Neighborhood Hits	23
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

COMP_HUMAN
NC score	0.159621 (rank : 90)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	165	Target Neighborhood Hits	258	Shared Neighborhood Hits	26
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

COMP_MOUSE
NC score	0.159528 (rank : 91)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	165	Target Neighborhood Hits	290	Shared Neighborhood Hits	29
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

ADA19_MOUSE
NC score	0.157946 (rank : 92)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	165	Target Neighborhood Hits	315	Shared Neighborhood Hits	59
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

TSP4_HUMAN
NC score	0.153144 (rank : 93)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	165	Target Neighborhood Hits	277	Shared Neighborhood Hits	24
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_MOUSE
NC score	0.152534 (rank : 94)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	165	Target Neighborhood Hits	276	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

FRAS1_HUMAN
NC score	0.151699 (rank : 95)	θ value	3.19293e-05 (rank : 66)
Query Neighborhood Hits	165	Target Neighborhood Hits	759	Shared Neighborhood Hits	83
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

ADA28_MOUSE
NC score	0.149058 (rank : 96)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	165	Target Neighborhood Hits	241	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ADA19_HUMAN
NC score	0.148972 (rank : 97)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	165	Target Neighborhood Hits	381	Shared Neighborhood Hits	60
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

RSPO2_HUMAN
NC score	0.148945 (rank : 98)	θ value	0.0113563 (rank : 80)
Query Neighborhood Hits	165	Target Neighborhood Hits	90	Shared Neighborhood Hits	39
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

WISP2_HUMAN
NC score	0.145442 (rank : 99)	θ value	1.81305 (rank : 119)
Query Neighborhood Hits	165	Target Neighborhood Hits	126	Shared Neighborhood Hits	56
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

ADA28_HUMAN
NC score	0.144486 (rank : 100)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	165	Target Neighborhood Hits	244	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ADA33_HUMAN
NC score	0.144308 (rank : 101)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	165	Target Neighborhood Hits	264	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

WISP2_MOUSE
NC score	0.143343 (rank : 102)	θ value	3.0926 (rank : 133)
Query Neighborhood Hits	165	Target Neighborhood Hits	129	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

ELTD1_HUMAN
NC score	0.142614 (rank : 103)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	165	Target Neighborhood Hits	269	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

ADA12_HUMAN
NC score	0.140046 (rank : 104)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	165	Target Neighborhood Hits	224	Shared Neighborhood Hits	45
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA12_MOUSE
NC score	0.139337 (rank : 105)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	165	Target Neighborhood Hits	474	Shared Neighborhood Hits	59
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADEC1_HUMAN
NC score	0.136426 (rank : 106)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	165	Target Neighborhood Hits	80	Shared Neighborhood Hits	27
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

WISP1_MOUSE
NC score	0.136068 (rank : 107)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	165	Target Neighborhood Hits	123	Shared Neighborhood Hits	51
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

CO9_HUMAN
NC score	0.136010 (rank : 108)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	165	Target Neighborhood Hits	147	Shared Neighborhood Hits	24
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

ADAM9_MOUSE
NC score	0.135416 (rank : 109)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	165	Target Neighborhood Hits	325	Shared Neighborhood Hits	50
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

RSPO2_MOUSE
NC score	0.135181 (rank : 110)	θ value	0.0736092 (rank : 88)
Query Neighborhood Hits	165	Target Neighborhood Hits	88	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

GP113_HUMAN
NC score	0.135045 (rank : 111)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	165	Target Neighborhood Hits	102	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IZF5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3	Gene names	GPR113, PGR23
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 113 precursor (G-protein coupled receptor PGR23).

ADA15_HUMAN
NC score	0.133539 (rank : 112)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	165	Target Neighborhood Hits	288	Shared Neighborhood Hits	56
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

ELTD1_MOUSE
NC score	0.131468 (rank : 113)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	165	Target Neighborhood Hits	288	Shared Neighborhood Hits	23
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

ADA33_MOUSE
NC score	0.130449 (rank : 114)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	165	Target Neighborhood Hits	231	Shared Neighborhood Hits	54
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADAM7_MOUSE
NC score	0.129853 (rank : 115)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	165	Target Neighborhood Hits	200	Shared Neighborhood Hits	49
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADAM7_HUMAN
NC score	0.129209 (rank : 116)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	165	Target Neighborhood Hits	221	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ADAM9_HUMAN
NC score	0.128590 (rank : 117)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	165	Target Neighborhood Hits	243	Shared Neighborhood Hits	48
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

WISP1_HUMAN
NC score	0.128069 (rank : 118)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	165	Target Neighborhood Hits	121	Shared Neighborhood Hits	55
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

EMR1_MOUSE
NC score	0.127060 (rank : 119)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	165	Target Neighborhood Hits	349	Shared Neighborhood Hits	33
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

CD97_HUMAN
NC score	0.124441 (rank : 120)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	165	Target Neighborhood Hits	353	Shared Neighborhood Hits	31
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

GP116_HUMAN
NC score	0.123624 (rank : 121)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	165	Target Neighborhood Hits	167	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

EMR1_HUMAN
NC score	0.123105 (rank : 122)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	165	Target Neighborhood Hits	382	Shared Neighborhood Hits	36
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EMR4_MOUSE
NC score	0.121511 (rank : 123)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	165	Target Neighborhood Hits	191	Shared Neighborhood Hits	13
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

GP110_HUMAN
NC score	0.119560 (rank : 124)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	165	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	Q5T601, Q5KU15, Q5T5Z9, Q86SM1, Q8IXE3, Q8IZF8, Q96DQ1	Gene names	GPR110, PGR19
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 110 precursor (G-protein coupled receptor PGR19) (G-protein coupled receptor KPG_012).

ADA15_MOUSE
NC score	0.118299 (rank : 125)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	165	Target Neighborhood Hits	324	Shared Neighborhood Hits	56
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

CD97_MOUSE
NC score	0.118016 (rank : 126)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	165	Target Neighborhood Hits	295	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

EMR2_HUMAN
NC score	0.117358 (rank : 127)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	165	Target Neighborhood Hits	345	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

GP133_HUMAN
NC score	0.116065 (rank : 128)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	165	Target Neighborhood Hits	115	Shared Neighborhood Hits	7
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

GP110_MOUSE
NC score	0.113333 (rank : 129)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	165	Target Neighborhood Hits	92	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VEC3, Q8BMV8	Gene names	Gpr110
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 110 precursor.

ADA22_HUMAN
NC score	0.112578 (rank : 130)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	165	Target Neighborhood Hits	211	Shared Neighborhood Hits	45
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

KR106_HUMAN
NC score	0.112368 (rank : 131)	θ value	1.06291 (rank : 110)
Query Neighborhood Hits	165	Target Neighborhood Hits	347	Shared Neighborhood Hits	51
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

GP128_HUMAN
NC score	0.112235 (rank : 132)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	165	Target Neighborhood Hits	135	Shared Neighborhood Hits	10
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

CYR61_HUMAN
NC score	0.111744 (rank : 133)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	165	Target Neighborhood Hits	159	Shared Neighborhood Hits	60
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

ADM1B_MOUSE
NC score	0.111347 (rank : 134)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	165	Target Neighborhood Hits	236	Shared Neighborhood Hits	48
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

EMR3_HUMAN
NC score	0.110705 (rank : 135)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	165	Target Neighborhood Hits	245	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

GP115_HUMAN
NC score	0.109882 (rank : 136)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	165	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZF3, Q5T5B5, Q5T5B6, Q86SN9, Q8IXE6	Gene names	GPR115, PGR18
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 (G-protein coupled receptor PGR18).

ADEC1_MOUSE
NC score	0.109097 (rank : 137)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	165	Target Neighborhood Hits	85	Shared Neighborhood Hits	28
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADA21_MOUSE
NC score	0.108962 (rank : 138)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	165	Target Neighborhood Hits	172	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

ADA24_MOUSE
NC score	0.108298 (rank : 139)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	165	Target Neighborhood Hits	230	Shared Neighborhood Hits	52
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ADM1A_MOUSE
NC score	0.107617 (rank : 140)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	165	Target Neighborhood Hits	230	Shared Neighborhood Hits	50
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ADA23_MOUSE
NC score	0.107530 (rank : 141)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	165	Target Neighborhood Hits	245	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

KRA51_HUMAN
NC score	0.107384 (rank : 142)	θ value	0.365318 (rank : 96)
Query Neighborhood Hits	165	Target Neighborhood Hits	288	Shared Neighborhood Hits	44
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

GPR97_MOUSE
NC score	0.107200 (rank : 143)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	165	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R0T6	Gene names	Gpr97
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor.

ADA22_MOUSE
NC score	0.106866 (rank : 144)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	165	Target Neighborhood Hits	225	Shared Neighborhood Hits	46
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

GP115_MOUSE
NC score	0.106187 (rank : 145)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	165	Target Neighborhood Hits	69	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D2L6	Gene names	Gpr115
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 precursor.

LPHN3_HUMAN
NC score	0.106004 (rank : 146)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	165	Target Neighborhood Hits	139	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

CRIM1_HUMAN
NC score	0.104419 (rank : 147)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	165	Target Neighborhood Hits	362	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

KR104_HUMAN
NC score	0.104350 (rank : 148)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	165	Target Neighborhood Hits	313	Shared Neighborhood Hits	37
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

ADA23_HUMAN
NC score	0.104063 (rank : 149)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	165	Target Neighborhood Hits	235	Shared Neighborhood Hits	45
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

GPR97_HUMAN
NC score	0.103460 (rank : 150)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	165	Target Neighborhood Hits	86	Shared Neighborhood Hits	6
SwissProt Accessions	Q86Y34, Q6ZMF4, Q86SL9, Q8IZF1	Gene names	GPR97, PGR26
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor (G-protein coupled receptor PGR26).

LPHN1_HUMAN
NC score	0.103458 (rank : 151)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	165	Target Neighborhood Hits	155	Shared Neighborhood Hits	6
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

LPHN2_HUMAN
NC score	0.102273 (rank : 152)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	165	Target Neighborhood Hits	136	Shared Neighborhood Hits	6
SwissProt Accessions	O95490, O94882, Q5VX76, Q9UKY5, Q9UKY6	Gene names	LPHN2, KIAA0786, LEC1, LPHH1
Domain Architecture
Description	Latrophilin-2 precursor (Calcium-independent alpha-latrotoxin receptor 2) (Latrophilin homolog 1) (Lectomedin-1).

ADA25_MOUSE
NC score	0.102213 (rank : 153)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	165	Target Neighborhood Hits	213	Shared Neighborhood Hits	45
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

KR107_HUMAN
NC score	0.101843 (rank : 154)	θ value	0.0431538 (rank : 84)
Query Neighborhood Hits	165	Target Neighborhood Hits	330	Shared Neighborhood Hits	41
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

ADA29_HUMAN
NC score	0.101628 (rank : 155)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	165	Target Neighborhood Hits	247	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

SEM6B_MOUSE
NC score	0.101101 (rank : 156)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	165	Target Neighborhood Hits	200	Shared Neighborhood Hits	12
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

SEM6B_HUMAN
NC score	0.101096 (rank : 157)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	165	Target Neighborhood Hits	187	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

NOV_HUMAN
NC score	0.101080 (rank : 158)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	165	Target Neighborhood Hits	128	Shared Neighborhood Hits	48
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

ADA21_HUMAN
NC score	0.101035 (rank : 159)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	165	Target Neighborhood Hits	181	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

ADA11_MOUSE
NC score	0.100252 (rank : 160)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	165	Target Neighborhood Hits	263	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

SEM6C_HUMAN
NC score	0.100171 (rank : 161)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	165	Target Neighborhood Hits	117	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H3T2, Q5JR71, Q8WXT8, Q8WXT9, Q8WXU0, Q96JF8	Gene names	SEMA6C, KIAA1869, SEMAY
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

GPR64_MOUSE
NC score	0.100090 (rank : 162)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	165	Target Neighborhood Hits	156	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

GP144_HUMAN
NC score	0.099999 (rank : 163)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	165	Target Neighborhood Hits	108	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

GPR64_HUMAN
NC score	0.099886 (rank : 164)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	165	Target Neighborhood Hits	207	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

SEM6C_MOUSE
NC score	0.099791 (rank : 165)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	165	Target Neighborhood Hits	352	Shared Neighborhood Hits	20
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

AD26A_MOUSE
NC score	0.099484 (rank : 166)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	165	Target Neighborhood Hits	165	Shared Neighborhood Hits	44
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

NOV_MOUSE
NC score	0.098252 (rank : 167)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	165	Target Neighborhood Hits	130	Shared Neighborhood Hits	48
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

SEM6A_MOUSE
NC score	0.097237 (rank : 168)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	165	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	O35464, Q6P5A8, Q6PCN9, Q9EQ71	Gene names	Sema6a, Semaq
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1) (Semaphorin Q) (Sema Q).

ZAN_MOUSE
NC score	0.097061 (rank : 169)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	165	Target Neighborhood Hits	808	Shared Neighborhood Hits	70
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

KR101_HUMAN
NC score	0.096808 (rank : 170)	θ value	3.0926 (rank : 126)
Query Neighborhood Hits	165	Target Neighborhood Hits	261	Shared Neighborhood Hits	38
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

SEM6A_HUMAN
NC score	0.096613 (rank : 171)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	165	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H2E6, Q9P2H9	Gene names	SEMA6A, KIAA1368
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1).

SEM6D_MOUSE
NC score	0.096465 (rank : 172)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	165	Target Neighborhood Hits	161	Shared Neighborhood Hits	7
SwissProt Accessions	Q76KF0, Q76KF1, Q76KF2, Q76KF3, Q76KF4, Q80TD0	Gene names	Sema6d, Kiaa1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

GP111_HUMAN
NC score	0.096352 (rank : 173)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	165	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IZF7, Q86SL6, Q8NGU5, Q8TDT5	Gene names	GPR111, PGR20
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 111 (G-protein coupled receptor PGR20).

GP128_MOUSE
NC score	0.096228 (rank : 174)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	165	Target Neighborhood Hits	141	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BM96, Q80T42	Gene names	Gpr128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

SEM4C_HUMAN
NC score	0.096188 (rank : 175)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	165	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q9C0C4, Q7Z5X0	Gene names	SEMA4C, KIAA1739
Domain Architecture
Description	Semaphorin-4C precursor.

SEM6D_HUMAN
NC score	0.096185 (rank : 176)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	165	Target Neighborhood Hits	169	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFY4, Q8NFY3, Q8NFY5, Q8NFY6, Q8NFY7, Q9P249	Gene names	SEMA6D, KIAA1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

GP112_HUMAN
NC score	0.095936 (rank : 177)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	165	Target Neighborhood Hits	441	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

KR102_HUMAN
NC score	0.094983 (rank : 178)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	165	Target Neighborhood Hits	264	Shared Neighborhood Hits	42
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

CYR61_MOUSE
NC score	0.094725 (rank : 179)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	165	Target Neighborhood Hits	156	Shared Neighborhood Hits	55
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

SEM3C_HUMAN
NC score	0.094347 (rank : 180)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	165	Target Neighborhood Hits	106	Shared Neighborhood Hits	10
SwissProt Accessions	Q99985	Gene names	SEMA3C, SEMAE
Domain Architecture
Description	Semaphorin-3C precursor (Semaphorin E) (Sema E).

SEM4A_HUMAN
NC score	0.094285 (rank : 181)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	165	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H3S1, Q8WUA9	Gene names	SEMA4A, SEMB
Domain Architecture
Description	Semaphorin-4A precursor (Semaphorin B) (Sema B).

SEM3C_MOUSE
NC score	0.094279 (rank : 182)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	165	Target Neighborhood Hits	113	Shared Neighborhood Hits	12
SwissProt Accessions	Q62181	Gene names	Sema3c, Semae, SemE
Domain Architecture
Description	Semaphorin-3C precursor (Semaphorin E) (Sema E).

PCSK5_MOUSE
NC score	0.094093 (rank : 183)	θ value	0.163984 (rank : 91)
Query Neighborhood Hits	165	Target Neighborhood Hits	613	Shared Neighborhood Hits	65
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

SEM4C_MOUSE
NC score	0.093444 (rank : 184)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	165	Target Neighborhood Hits	77	Shared Neighborhood Hits	5
SwissProt Accessions	Q64151	Gene names	Sema4c, Semacl1, Semai
Domain Architecture
Description	Semaphorin-4C precursor (Semaphorin I) (Sema I) (Semaphorin C-like 1) (M-Sema F).

SEM4A_MOUSE
NC score	0.093283 (rank : 185)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	165	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	Q62178	Gene names	Sema4a, Semab, SemB
Domain Architecture
Description	Semaphorin-4A precursor (Semaphorin B) (Sema B).

SEM3F_HUMAN
NC score	0.093011 (rank : 186)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	165	Target Neighborhood Hits	100	Shared Neighborhood Hits	14
SwissProt Accessions	Q13275, Q13274, Q13372, Q15704	Gene names	SEMA3F
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV) (Sema III/F).

MEGF6_HUMAN
NC score	0.092932 (rank : 187)	θ value	0.0330416 (rank : 83)
Query Neighborhood Hits	165	Target Neighborhood Hits	671	Shared Neighborhood Hits	73
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

VWF_HUMAN
NC score	0.091684 (rank : 188)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	165	Target Neighborhood Hits	396	Shared Neighborhood Hits	49
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

SEM4B_MOUSE
NC score	0.091339 (rank : 189)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	165	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	Q62179, Q4PKI6, Q69ZB7	Gene names	Sema4b, Kiaa1745, Semac, SemC
Domain Architecture	No domain graphic available
Description	Semaphorin-4B precursor (Semaphorin C) (Sema C).

SEM4D_HUMAN
NC score	0.091296 (rank : 190)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	165	Target Neighborhood Hits	139	Shared Neighborhood Hits	7
SwissProt Accessions	Q92854, Q7Z5S4	Gene names	SEMA4D, CD100
Domain Architecture
Description	Semaphorin-4D precursor (Leukocyte activation antigen CD100) (BB18) (A8) (GR3).

SEM4B_HUMAN
NC score	0.091246 (rank : 191)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	165	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NPR2, Q6UXE3, Q8WVP9, Q96FK5, Q9C0B8, Q9H691, Q9NPM8, Q9NPN0	Gene names	SEMA4B, KIAA1745
Domain Architecture
Description	Semaphorin-4B precursor.

GP126_HUMAN
NC score	0.090853 (rank : 192)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	165	Target Neighborhood Hits	187	Shared Neighborhood Hits	9
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

SEM4D_MOUSE
NC score	0.090437 (rank : 193)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	165	Target Neighborhood Hits	143	Shared Neighborhood Hits	10
SwissProt Accessions	O09126	Gene names	Sema4d, Semacl2, Semaj
Domain Architecture
Description	Semaphorin-4D precursor (Semaphorin J) (Sema J) (Semaphorin C-like 2) (M-Sema G).

BMPER_HUMAN
NC score	0.089838 (rank : 194)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	165	Target Neighborhood Hits	175	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

SEM4F_MOUSE
NC score	0.089538 (rank : 195)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	165	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z123, Q9R1Y1	Gene names	Sema4f, Semaw
Domain Architecture
Description	Semaphorin-4F precursor (Semaphorin W) (Sema W).

GP114_HUMAN
NC score	0.089470 (rank : 196)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	165	Target Neighborhood Hits	75	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZF4, Q6ZMH7, Q6ZML4, Q86SL8, Q8IZ14	Gene names	GPR114, PGR27
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 114 precursor (G-protein coupled receptor PGR27).

SEM3F_MOUSE
NC score	0.089337 (rank : 197)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	165	Target Neighborhood Hits	86	Shared Neighborhood Hits	6
SwissProt Accessions	O88632, O88633	Gene names	Sema3f
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV).

SEM4F_HUMAN
NC score	0.088565 (rank : 198)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	165	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	O95754, Q9NS35	Gene names	SEMA4F, SEMAM, SEMAW
Domain Architecture
Description	Semaphorin-4F precursor (Semaphorin W) (Sema W) (Semaphorin M) (Sema M).

SEM3A_HUMAN
NC score	0.087874 (rank : 199)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	165	Target Neighborhood Hits	78	Shared Neighborhood Hits	6
SwissProt Accessions	Q14563	Gene names	SEMA3A
Domain Architecture
Description	Semaphorin-3A precursor (Semaphorin III) (Sema III).

NELL1_HUMAN
NC score	0.087832 (rank : 200)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	165	Target Neighborhood Hits	451	Shared Neighborhood Hits	40
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

SEM3B_HUMAN
NC score	0.087816 (rank : 201)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	165	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	Q13214, Q8TB71, Q8TDV7, Q93018, Q96GX0	Gene names	SEMA3B, SEMA5
Domain Architecture
Description	Semaphorin-3B precursor (Semaphorin V) (Sema V) (Sema A(V)).

SEM3E_MOUSE
NC score	0.087684 (rank : 202)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	165	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	P70275, O09078, O09079	Gene names	Sema3e, Semah, Semh
Domain Architecture
Description	Semaphorin-3E precursor (Semaphorin H) (Sema H).

SEM3E_HUMAN
NC score	0.087183 (rank : 203)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	165	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	O15041, Q75M94, Q75M97	Gene names	SEMA3E, KIAA0331
Domain Architecture	No domain graphic available
Description	Semaphorin-3E precursor.

ADA11_HUMAN
NC score	0.086962 (rank : 204)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	165	Target Neighborhood Hits	259	Shared Neighborhood Hits	47
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

SEM3A_MOUSE
NC score	0.086750 (rank : 205)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	165	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	O08665, Q5BL08, Q62180, Q62215	Gene names	Sema3a, Semad, SemD
Domain Architecture
Description	Semaphorin-3A precursor (Semaphorin III) (Sema III) (Semaphorin D) (Sema D).

NELL2_MOUSE
NC score	0.086655 (rank : 206)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	165	Target Neighborhood Hits	436	Shared Neighborhood Hits	36
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

SEM3B_MOUSE
NC score	0.085733 (rank : 207)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	165	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	Q62177	Gene names	Sema3b, Sema, Semaa
Domain Architecture
Description	Semaphorin-3B precursor (Semaphorin A) (Sema A).

SEM4G_MOUSE
NC score	0.085325 (rank : 208)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	165	Target Neighborhood Hits	99	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WUH7	Gene names	Sema4g
Domain Architecture
Description	Semaphorin-4G precursor.

SEM3D_HUMAN
NC score	0.085251 (rank : 209)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	165	Target Neighborhood Hits	104	Shared Neighborhood Hits	6
SwissProt Accessions	O95025, Q6UW77, Q8NCQ1	Gene names	SEMA3D
Domain Architecture
Description	Semaphorin-3D precursor.

SEM7A_MOUSE
NC score	0.085185 (rank : 210)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	165	Target Neighborhood Hits	64	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QUR8, O88371	Gene names	Sema7a, Cd108, Semal, Semk1
Domain Architecture
Description	Semaphorin-7A precursor (Semaphorin L) (Sema L) (Semaphorin K1) (Sema K1) (CD108 antigen) (CDw108).

SEM3D_MOUSE
NC score	0.084607 (rank : 211)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	165	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BH34	Gene names	Sema3d
Domain Architecture	No domain graphic available
Description	Semaphorin-3D precursor.

STAB2_MOUSE
NC score	0.084182 (rank : 212)	θ value	1.38821 (rank : 113)
Query Neighborhood Hits	165	Target Neighborhood Hits	528	Shared Neighborhood Hits	52
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

SEM4G_HUMAN
NC score	0.084139 (rank : 213)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	165	Target Neighborhood Hits	88	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NTN9, Q9HCF3	Gene names	SEMA4G, KIAA1619
Domain Architecture
Description	Semaphorin-4G precursor.

BMPER_MOUSE
NC score	0.083941 (rank : 214)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	165	Target Neighborhood Hits	194	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

KRA98_HUMAN
NC score	0.083854 (rank : 215)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	165	Target Neighborhood Hits	185	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

NOTC3_MOUSE
NC score	0.083306 (rank : 216)	θ value	1.81305 (rank : 116)
Query Neighborhood Hits	165	Target Neighborhood Hits	975	Shared Neighborhood Hits	71
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

GPR56_HUMAN
NC score	0.083155 (rank : 217)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	165	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y653, O95966, Q8NGB3, Q96HB4	Gene names	GPR56, TM7LN4, TM7XN1
Domain Architecture
Description	G-protein coupled receptor 56 precursor (TM7XN1 protein).

SEM7A_HUMAN
NC score	0.083082 (rank : 218)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	165	Target Neighborhood Hits	67	Shared Neighborhood Hits	4
SwissProt Accessions	O75326	Gene names	SEMA7A, CD108, SEMAL
Domain Architecture
Description	Semaphorin-7A precursor (Semaphorin L) (Sema L) (Semaphorin K1) (Sema K1) (John-Milton-Hargen human blood group Ag) (JMH blood group antigen) (CD108 antigen) (CDw108).

ADAM2_MOUSE
NC score	0.082770 (rank : 219)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	165	Target Neighborhood Hits	209	Shared Neighborhood Hits	47
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

NOTC3_HUMAN
NC score	0.082538 (rank : 220)	θ value	0.0113563 (rank : 79)
Query Neighborhood Hits	165	Target Neighborhood Hits	1062	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

KR414_HUMAN
NC score	0.082158 (rank : 221)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	165	Target Neighborhood Hits	199	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

TENX_HUMAN
NC score	0.080788 (rank : 222)	θ value	0.0252991 (rank : 82)
Query Neighborhood Hits	165	Target Neighborhood Hits	789	Shared Neighborhood Hits	66
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

NELL2_HUMAN
NC score	0.080366 (rank : 223)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	165	Target Neighborhood Hits	449	Shared Neighborhood Hits	37
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

GP123_HUMAN
NC score	0.079973 (rank : 224)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	165	Target Neighborhood Hits	120	Shared Neighborhood Hits	7
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

WISP3_HUMAN
NC score	0.079740 (rank : 225)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	165	Target Neighborhood Hits	87	Shared Neighborhood Hits	37
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

ADA32_HUMAN
NC score	0.079420 (rank : 226)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	165	Target Neighborhood Hits	216	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

CELR2_HUMAN
NC score	0.079256 (rank : 227)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	165	Target Neighborhood Hits	657	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CTGF_HUMAN
NC score	0.078991 (rank : 228)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	165	Target Neighborhood Hits	128	Shared Neighborhood Hits	48
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

ROBO4_MOUSE
NC score	0.078588 (rank : 229)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	165	Target Neighborhood Hits	358	Shared Neighborhood Hits	18
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

CTGF_MOUSE
NC score	0.078581 (rank : 230)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	165	Target Neighborhood Hits	124	Shared Neighborhood Hits	46
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

NOTC4_HUMAN
NC score	0.077987 (rank : 231)	θ value	0.000786445 (rank : 74)
Query Neighborhood Hits	165	Target Neighborhood Hits	905	Shared Neighborhood Hits	60
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

GPR56_MOUSE
NC score	0.077618 (rank : 232)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	165	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K209, Q3UR17, Q9QZT2	Gene names	Gpr56, Cyt28
Domain Architecture
Description	G-protein coupled receptor 56 precursor (Serpentine receptor cyt28).

KR412_HUMAN
NC score	0.077185 (rank : 233)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	165	Target Neighborhood Hits	178	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

ADA17_MOUSE
NC score	0.076781 (rank : 234)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	165	Target Neighborhood Hits	201	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

KRA92_HUMAN
NC score	0.076692 (rank : 235)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	165	Target Neighborhood Hits	198	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

LCE1A_HUMAN
NC score	0.076322 (rank : 236)	θ value	2.36792 (rank : 121)
Query Neighborhood Hits	165	Target Neighborhood Hits	47	Shared Neighborhood Hits	10
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

ROBO4_HUMAN
NC score	0.076150 (rank : 237)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	165	Target Neighborhood Hits	364	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

GPR98_MOUSE
NC score	0.075897 (rank : 238)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	165	Target Neighborhood Hits	206	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

ADA32_MOUSE
NC score	0.075836 (rank : 239)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	165	Target Neighborhood Hits	219	Shared Neighborhood Hits	46
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA20_HUMAN
NC score	0.075741 (rank : 240)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	165	Target Neighborhood Hits	143	Shared Neighborhood Hits	38
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

ADA17_HUMAN
NC score	0.075258 (rank : 241)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	165	Target Neighborhood Hits	223	Shared Neighborhood Hits	43
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

SREC_HUMAN
NC score	0.074831 (rank : 242)	θ value	1.38821 (rank : 112)
Query Neighborhood Hits	165	Target Neighborhood Hits	645	Shared Neighborhood Hits	63
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

ADA10_HUMAN
NC score	0.074826 (rank : 243)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	165	Target Neighborhood Hits	189	Shared Neighborhood Hits	40
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

VWF_MOUSE
NC score	0.074374 (rank : 244)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	165	Target Neighborhood Hits	381	Shared Neighborhood Hits	41
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

NOTC4_MOUSE
NC score	0.074181 (rank : 245)	θ value	0.00509761 (rank : 76)
Query Neighborhood Hits	165	Target Neighborhood Hits	872	Shared Neighborhood Hits	56
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

CRDL2_MOUSE
NC score	0.074161 (rank : 246)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	165	Target Neighborhood Hits	81	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

STAB2_HUMAN
NC score	0.074156 (rank : 247)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	165	Target Neighborhood Hits	534	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

LTBP4_MOUSE
NC score	0.073893 (rank : 248)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	165	Target Neighborhood Hits	607	Shared Neighborhood Hits	53
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

GPR98_HUMAN
NC score	0.073624 (rank : 249)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	165	Target Neighborhood Hits	202	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

KR105_HUMAN
NC score	0.073512 (rank : 250)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	165	Target Neighborhood Hits	271	Shared Neighborhood Hits	32
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

ADA18_MOUSE
NC score	0.073499 (rank : 251)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	165	Target Neighborhood Hits	227	Shared Neighborhood Hits	45
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

NOTC1_HUMAN
NC score	0.073390 (rank : 252)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	165	Target Neighborhood Hits	906	Shared Neighborhood Hits	63
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

KRA15_HUMAN
NC score	0.073216 (rank : 253)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	165	Target Neighborhood Hits	126	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

LRP2_HUMAN
NC score	0.073191 (rank : 254)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	165	Target Neighborhood Hits	573	Shared Neighborhood Hits	53
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

CREL1_MOUSE
NC score	0.073190 (rank : 255)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	165	Target Neighborhood Hits	524	Shared Neighborhood Hits	40
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CELR1_HUMAN
NC score	0.072628 (rank : 256)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	165	Target Neighborhood Hits	613	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

FBN1_HUMAN
NC score	0.072537 (rank : 257)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	165	Target Neighborhood Hits	557	Shared Neighborhood Hits	51
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

CELR1_MOUSE
NC score	0.072520 (rank : 258)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	165	Target Neighborhood Hits	617	Shared Neighborhood Hits	38
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

ADA10_MOUSE
NC score	0.072490 (rank : 259)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	165	Target Neighborhood Hits	194	Shared Neighborhood Hits	40
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

NOTC1_MOUSE
NC score	0.072483 (rank : 260)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	165	Target Neighborhood Hits	916	Shared Neighborhood Hits	59
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

MUC5B_HUMAN
NC score	0.072086 (rank : 261)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	165	Target Neighborhood Hits	1020	Shared Neighborhood Hits	56
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

CELR2_MOUSE
NC score	0.071961 (rank : 262)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	165	Target Neighborhood Hits	584	Shared Neighborhood Hits	39
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

STAB1_HUMAN
NC score	0.071678 (rank : 263)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	165	Target Neighborhood Hits	546	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

DLL1_MOUSE
NC score	0.071523 (rank : 264)	θ value	0.62314 (rank : 100)
Query Neighborhood Hits	165	Target Neighborhood Hits	456	Shared Neighborhood Hits	50
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

NOTC2_HUMAN
NC score	0.071260 (rank : 265)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	165	Target Neighborhood Hits	1113	Shared Neighborhood Hits	72
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

CREL1_HUMAN
NC score	0.071035 (rank : 266)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	165	Target Neighborhood Hits	441	Shared Neighborhood Hits	37
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

DLL1_HUMAN
NC score	0.070821 (rank : 267)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	165	Target Neighborhood Hits	455	Shared Neighborhood Hits	49
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

LRP8_HUMAN
NC score	0.070591 (rank : 268)	θ value	1.06291 (rank : 111)
Query Neighborhood Hits	165	Target Neighborhood Hits	346	Shared Neighborhood Hits	36
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

JAG1_HUMAN
NC score	0.070067 (rank : 269)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	165	Target Neighborhood Hits	514	Shared Neighborhood Hits	48
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

NOTC2_MOUSE
NC score	0.070030 (rank : 270)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	165	Target Neighborhood Hits	1069	Shared Neighborhood Hits	57
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

FBN1_MOUSE
NC score	0.069854 (rank : 271)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	165	Target Neighborhood Hits	563	Shared Neighborhood Hits	50
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

CRFR1_HUMAN
NC score	0.069707 (rank : 272)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	165	Target Neighborhood Hits	82	Shared Neighborhood Hits	6
SwissProt Accessions	P34998, Q13008, Q9UK64	Gene names	CRHR1, CRFR, CRFR1, CRHR
Domain Architecture
Description	Corticotropin-releasing factor receptor 1 precursor (CRF-R) (CRF1) (Corticotropin-releasing hormone receptor 1) (CRH-R 1).

FBN2_MOUSE
NC score	0.069666 (rank : 273)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	165	Target Neighborhood Hits	549	Shared Neighborhood Hits	53
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

CRFR1_MOUSE
NC score	0.069524 (rank : 274)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	165	Target Neighborhood Hits	83	Shared Neighborhood Hits	6
SwissProt Accessions	P35347	Gene names	Crhr1, Crhr
Domain Architecture
Description	Corticotropin-releasing factor receptor 1 precursor (CRF-R) (CRF1) (Corticotropin-releasing hormone receptor 1) (CRH-R 1).

FBN2_HUMAN
NC score	0.069428 (rank : 275)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	165	Target Neighborhood Hits	560	Shared Neighborhood Hits	52
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

LRP8_MOUSE
NC score	0.069426 (rank : 276)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	165	Target Neighborhood Hits	385	Shared Neighborhood Hits	39
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

FBN3_HUMAN
NC score	0.069375 (rank : 277)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	165	Target Neighborhood Hits	543	Shared Neighborhood Hits	47
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

C1QR1_MOUSE
NC score	0.068629 (rank : 278)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	165	Target Neighborhood Hits	342	Shared Neighborhood Hits	30
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

CELR3_HUMAN
NC score	0.068617 (rank : 279)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	165	Target Neighborhood Hits	680	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CRFR2_HUMAN
NC score	0.068491 (rank : 280)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	165	Target Neighborhood Hits	76	Shared Neighborhood Hits	7
SwissProt Accessions	Q13324, O43461, Q99431	Gene names	CRHR2, CRF2R, CRH2R
Domain Architecture
Description	Corticotropin-releasing factor receptor 2 precursor (CRF-R 2) (CRF2) (Corticotropin-releasing hormone receptor 2) (CRH-R 2).

JAG2_HUMAN
NC score	0.068431 (rank : 281)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	165	Target Neighborhood Hits	491	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

TRBM_HUMAN
NC score	0.068401 (rank : 282)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	165	Target Neighborhood Hits	339	Shared Neighborhood Hits	32
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

JAG1_MOUSE
NC score	0.068365 (rank : 283)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	165	Target Neighborhood Hits	518	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

STAB1_MOUSE
NC score	0.068327 (rank : 284)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	165	Target Neighborhood Hits	566	Shared Neighborhood Hits	47
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

UROM_HUMAN
NC score	0.068045 (rank : 285)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	165	Target Neighborhood Hits	284	Shared Neighborhood Hits	25
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

LTBP2_HUMAN
NC score	0.067999 (rank : 286)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	165	Target Neighborhood Hits	552	Shared Neighborhood Hits	50
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

KRA13_HUMAN
NC score	0.067936 (rank : 287)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	165	Target Neighborhood Hits	144	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

NFX1_HUMAN
NC score	0.067886 (rank : 288)	θ value	2.36792 (rank : 122)
Query Neighborhood Hits	165	Target Neighborhood Hits	405	Shared Neighborhood Hits	37
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

C1QR1_HUMAN
NC score	0.067698 (rank : 289)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	165	Target Neighborhood Hits	493	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

CELR3_MOUSE
NC score	0.067532 (rank : 290)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	165	Target Neighborhood Hits	687	Shared Neighborhood Hits	51
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

CUBN_MOUSE
NC score	0.067417 (rank : 291)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	165	Target Neighborhood Hits	477	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

KRA59_HUMAN
NC score	0.067324 (rank : 292)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	165	Target Neighborhood Hits	310	Shared Neighborhood Hits	35
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

DLL4_HUMAN
NC score	0.066994 (rank : 293)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	165	Target Neighborhood Hits	435	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

KRA93_HUMAN
NC score	0.066853 (rank : 294)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	165	Target Neighborhood Hits	203	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

CRDL2_HUMAN
NC score	0.066840 (rank : 295)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	165	Target Neighborhood Hits	99	Shared Neighborhood Hits	14
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

CALCR_HUMAN
NC score	0.066719 (rank : 296)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	165	Target Neighborhood Hits	67	Shared Neighborhood Hits	6
SwissProt Accessions	P30988, O14585, Q13941, Q6DJU8, Q6T712	Gene names	CALCR
Domain Architecture
Description	Calcitonin receptor precursor (CT-R).

NID1_HUMAN
NC score	0.066673 (rank : 297)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	165	Target Neighborhood Hits	329	Shared Neighborhood Hits	29
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

FBLN1_HUMAN
NC score	0.066535 (rank : 298)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	165	Target Neighborhood Hits	324	Shared Neighborhood Hits	29
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

KR109_HUMAN
NC score	0.066429 (rank : 299)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	165	Target Neighborhood Hits	226	Shared Neighborhood Hits	32
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

JAG2_MOUSE
NC score	0.066388 (rank : 300)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	165	Target Neighborhood Hits	504	Shared Neighborhood Hits	48
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

PGBM_HUMAN
NC score	0.066174 (rank : 301)	θ value	2.36792 (rank : 123)
Query Neighborhood Hits	165	Target Neighborhood Hits	1113	Shared Neighborhood Hits	59
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

FBLN3_HUMAN
NC score	0.066109 (rank : 302)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	165	Target Neighborhood Hits	293	Shared Neighborhood Hits	29
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

LTBP3_MOUSE
NC score	0.065898 (rank : 303)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	165	Target Neighborhood Hits	475	Shared Neighborhood Hits	44
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP2_MOUSE
NC score	0.065572 (rank : 304)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	165	Target Neighborhood Hits	617	Shared Neighborhood Hits	52
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

CRFR2_MOUSE
NC score	0.065458 (rank : 305)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	165	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	Q60748, Q60783, Q60808	Gene names	Crhr2, Crf2r
Domain Architecture
Description	Corticotropin-releasing factor receptor 2 precursor (CRF-R 2) (CRF2) (Corticotropin-releasing hormone receptor 2) (CRH-R 2) (CRF-RB) (CRH- R2).

FBLN1_MOUSE
NC score	0.065390 (rank : 306)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	165	Target Neighborhood Hits	329	Shared Neighborhood Hits	32
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

LTBP3_HUMAN
NC score	0.065344 (rank : 307)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	165	Target Neighborhood Hits	502	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

FBLN4_MOUSE
NC score	0.065209 (rank : 308)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	165	Target Neighborhood Hits	270	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

NID1_MOUSE
NC score	0.065112 (rank : 309)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	165	Target Neighborhood Hits	335	Shared Neighborhood Hits	29
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

TRBM_MOUSE
NC score	0.064965 (rank : 310)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	165	Target Neighborhood Hits	361	Shared Neighborhood Hits	37
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

LTB1L_HUMAN
NC score	0.064888 (rank : 311)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	165	Target Neighborhood Hits	553	Shared Neighborhood Hits	49
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LDLR_HUMAN
NC score	0.064677 (rank : 312)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	165	Target Neighborhood Hits	375	Shared Neighborhood Hits	39
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP1B_HUMAN
NC score	0.064461 (rank : 313)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	165	Target Neighborhood Hits	602	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

FBLN2_MOUSE
NC score	0.064425 (rank : 314)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	165	Target Neighborhood Hits	505	Shared Neighborhood Hits	36
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

LRP1_HUMAN
NC score	0.064422 (rank : 315)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	165	Target Neighborhood Hits	617	Shared Neighborhood Hits	61
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

CUBN_HUMAN
NC score	0.063982 (rank : 316)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	165	Target Neighborhood Hits	482	Shared Neighborhood Hits	40
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

LDLR_MOUSE
NC score	0.063970 (rank : 317)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	165	Target Neighborhood Hits	382	Shared Neighborhood Hits	41
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

CRUM1_HUMAN
NC score	0.063951 (rank : 318)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	165	Target Neighborhood Hits	457	Shared Neighborhood Hits	48
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

DLL4_MOUSE
NC score	0.063818 (rank : 319)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	165	Target Neighborhood Hits	440	Shared Neighborhood Hits	49
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

KRA47_HUMAN
NC score	0.063429 (rank : 320)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	165	Target Neighborhood Hits	204	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

FBLN5_HUMAN
NC score	0.063201 (rank : 321)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	165	Target Neighborhood Hits	329	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

CRUM2_HUMAN
NC score	0.063200 (rank : 322)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	165	Target Neighborhood Hits	453	Shared Neighborhood Hits	43
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

PCSK5_HUMAN
NC score	0.063178 (rank : 323)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	165	Target Neighborhood Hits	291	Shared Neighborhood Hits	46
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

GP125_HUMAN
NC score	0.063049 (rank : 324)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	165	Target Neighborhood Hits	327	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

NID2_HUMAN
NC score	0.062985 (rank : 325)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	165	Target Neighborhood Hits	456	Shared Neighborhood Hits	43
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

LTB1S_HUMAN
NC score	0.062921 (rank : 326)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	165	Target Neighborhood Hits	502	Shared Neighborhood Hits	44
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

PERF_HUMAN
NC score	0.062829 (rank : 327)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	165	Target Neighborhood Hits	48	Shared Neighborhood Hits	12
SwissProt Accessions	P14222, Q86WX7	Gene names	PRF1, PFP
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (PFP) (Cytolysin).

KRA58_HUMAN
NC score	0.062744 (rank : 328)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	165	Target Neighborhood Hits	324	Shared Neighborhood Hits	32
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

ROBO3_HUMAN
NC score	0.062569 (rank : 329)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	165	Target Neighborhood Hits	570	Shared Neighborhood Hits	22
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

LRP4_HUMAN
NC score	0.062550 (rank : 330)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	165	Target Neighborhood Hits	355	Shared Neighborhood Hits	37
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

PGBM_MOUSE
NC score	0.062548 (rank : 331)	θ value	0.62314 (rank : 101)
Query Neighborhood Hits	165	Target Neighborhood Hits	1073	Shared Neighborhood Hits	58
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

ROBO2_MOUSE
NC score	0.062517 (rank : 332)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	165	Target Neighborhood Hits	504	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

SREC2_MOUSE
NC score	0.062501 (rank : 333)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	165	Target Neighborhood Hits	605	Shared Neighborhood Hits	56
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

FBLN2_HUMAN
NC score	0.062177 (rank : 334)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	165	Target Neighborhood Hits	392	Shared Neighborhood Hits	29
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

DNER_HUMAN
NC score	0.062022 (rank : 335)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	165	Target Neighborhood Hits	460	Shared Neighborhood Hits	45
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

LTB1L_MOUSE
NC score	0.061976 (rank : 336)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	165	Target Neighborhood Hits	514	Shared Neighborhood Hits	47
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

FBLN4_HUMAN
NC score	0.061972 (rank : 337)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	165	Target Neighborhood Hits	278	Shared Neighborhood Hits	26
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

LRP1B_MOUSE
NC score	0.061952 (rank : 338)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	165	Target Neighborhood Hits	606	Shared Neighborhood Hits	56
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

ROBO2_HUMAN
NC score	0.061907 (rank : 339)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	165	Target Neighborhood Hits	479	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HCK4, O43608	Gene names	ROBO2, KIAA1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

CRUM1_MOUSE
NC score	0.061770 (rank : 340)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	165	Target Neighborhood Hits	444	Shared Neighborhood Hits	48
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

ROBO1_HUMAN
NC score	0.061557 (rank : 341)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	165	Target Neighborhood Hits	529	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

LRP4_MOUSE
NC score	0.061359 (rank : 342)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	165	Target Neighborhood Hits	351	Shared Neighborhood Hits	39
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

MEGF8_HUMAN
NC score	0.061142 (rank : 343)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	165	Target Neighborhood Hits	528	Shared Neighborhood Hits	46
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

KR108_HUMAN
NC score	0.061095 (rank : 344)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	165	Target Neighborhood Hits	226	Shared Neighborhood Hits	34
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

FBLN3_MOUSE
NC score	0.060804 (rank : 345)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	165	Target Neighborhood Hits	279	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

ROBO3_MOUSE
NC score	0.060787 (rank : 346)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	165	Target Neighborhood Hits	524	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

ROBO1_MOUSE
NC score	0.060650 (rank : 347)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	165	Target Neighborhood Hits	559	Shared Neighborhood Hits	17
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

ADAM2_HUMAN
NC score	0.060600 (rank : 348)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	165	Target Neighborhood Hits	175	Shared Neighborhood Hits	35
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

SCUB3_MOUSE
NC score	0.060538 (rank : 349)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	165	Target Neighborhood Hits	442	Shared Neighborhood Hits	40
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

ADA18_HUMAN
NC score	0.060404 (rank : 350)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	165	Target Neighborhood Hits	184	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

KRA53_HUMAN
NC score	0.060384 (rank : 351)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	165	Target Neighborhood Hits	331	Shared Neighborhood Hits	39
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

FBLN5_MOUSE
NC score	0.060322 (rank : 352)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	165	Target Neighborhood Hits	317	Shared Neighborhood Hits	31
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

KR10B_HUMAN
NC score	0.060288 (rank : 353)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	165	Target Neighborhood Hits	269	Shared Neighborhood Hits	37
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

SREC2_HUMAN
NC score	0.060104 (rank : 354)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	165	Target Neighborhood Hits	645	Shared Neighborhood Hits	53
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

LTB1S_MOUSE
NC score	0.060080 (rank : 355)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	165	Target Neighborhood Hits	479	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

UROM_MOUSE
NC score	0.059607 (rank : 356)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	165	Target Neighborhood Hits	276	Shared Neighborhood Hits	29
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

SCUB3_HUMAN
NC score	0.059195 (rank : 357)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	165	Target Neighborhood Hits	428	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

NID2_MOUSE
NC score	0.058947 (rank : 358)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	165	Target Neighborhood Hits	338	Shared Neighborhood Hits	29
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

ZAN_HUMAN
NC score	0.058596 (rank : 359)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	165	Target Neighborhood Hits	679	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

KRA45_HUMAN
NC score	0.058334 (rank : 360)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	165	Target Neighborhood Hits	194	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

SORL_HUMAN
NC score	0.058182 (rank : 361)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	165	Target Neighborhood Hits	440	Shared Neighborhood Hits	41
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

DLL3_HUMAN
NC score	0.058002 (rank : 362)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	165	Target Neighborhood Hits	419	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

EGF_HUMAN
NC score	0.057983 (rank : 363)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	165	Target Neighborhood Hits	343	Shared Neighborhood Hits	30
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

PIGQ_HUMAN
NC score	0.057920 (rank : 364)	θ value	0.00665767 (rank : 77)
Query Neighborhood Hits	165	Target Neighborhood Hits	84	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BRB3, O14927, Q96G00, Q96S22, Q9UJH4	Gene names	PIGQ, GPI1
Domain Architecture
Description	Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q (EC 2.4.1.198) (Phosphatidylinositol-glycan biosynthesis class Q protein) (PIG-Q) (N-acetylglucosamyl transferase component GPI1).

DLL3_MOUSE
NC score	0.057903 (rank : 365)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	165	Target Neighborhood Hits	399	Shared Neighborhood Hits	45
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

MUC2_HUMAN
NC score	0.057759 (rank : 366)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	165	Target Neighborhood Hits	906	Shared Neighborhood Hits	43
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

GP125_MOUSE
NC score	0.057420 (rank : 367)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	165	Target Neighborhood Hits	329	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

MEGF8_MOUSE
NC score	0.057255 (rank : 368)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	165	Target Neighborhood Hits	520	Shared Neighborhood Hits	46
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

ZO1_HUMAN
NC score	0.057184 (rank : 369)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	165	Target Neighborhood Hits	474	Shared Neighborhood Hits	14
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

EGF_MOUSE
NC score	0.056756 (rank : 370)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	165	Target Neighborhood Hits	358	Shared Neighborhood Hits	30
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

ZO1_MOUSE
NC score	0.056498 (rank : 371)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	165	Target Neighborhood Hits	453	Shared Neighborhood Hits	10
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

VIPR2_HUMAN
NC score	0.056316 (rank : 372)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	165	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	P41587, Q13053, Q15870	Gene names	VIPR2, VIP2R
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) (Helodermin-preferring VIP receptor).

KRA11_HUMAN
NC score	0.056153 (rank : 373)	θ value	2.36792 (rank : 120)
Query Neighborhood Hits	165	Target Neighborhood Hits	155	Shared Neighborhood Hits	26
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

CRDL1_HUMAN
NC score	0.056145 (rank : 374)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	165	Target Neighborhood Hits	75	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BU40, Q9Y3H7	Gene names	CHRDL1, NRLN1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

DNER_MOUSE
NC score	0.055470 (rank : 375)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	165	Target Neighborhood Hits	413	Shared Neighborhood Hits	45
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

CHRD_HUMAN
NC score	0.055353 (rank : 376)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	165	Target Neighborhood Hits	102	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

KR10A_HUMAN
NC score	0.054697 (rank : 377)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	165	Target Neighborhood Hits	232	Shared Neighborhood Hits	29
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

CRDL1_MOUSE
NC score	0.054439 (rank : 378)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	165	Target Neighborhood Hits	81	Shared Neighborhood Hits	11
SwissProt Accessions	Q920C1, Q924K0, Q9EPZ9	Gene names	Chrdl1, Ng1, Nrln1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

PUNC_HUMAN
NC score	0.054399 (rank : 379)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	165	Target Neighborhood Hits	449	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

KRA54_HUMAN
NC score	0.054273 (rank : 380)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	165	Target Neighborhood Hits	270	Shared Neighborhood Hits	30
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

VLDLR_HUMAN
NC score	0.054103 (rank : 381)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	165	Target Neighborhood Hits	383	Shared Neighborhood Hits	35
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

AGRIN_HUMAN
NC score	0.053922 (rank : 382)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	165	Target Neighborhood Hits	582	Shared Neighborhood Hits	49
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

KRA42_HUMAN
NC score	0.053889 (rank : 383)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	165	Target Neighborhood Hits	149	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

SORL_MOUSE
NC score	0.053867 (rank : 384)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	165	Target Neighborhood Hits	439	Shared Neighborhood Hits	40
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

GRN_MOUSE
NC score	0.053288 (rank : 385)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	165	Target Neighborhood Hits	248	Shared Neighborhood Hits	29
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

DLK_MOUSE
NC score	0.053198 (rank : 386)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	165	Target Neighborhood Hits	374	Shared Neighborhood Hits	43
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

CALCR_MOUSE
NC score	0.053002 (rank : 387)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	165	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	Q60755	Gene names	Calcr
Domain Architecture
Description	Calcitonin receptor precursor (CT-R).

KR10C_HUMAN
NC score	0.052982 (rank : 388)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	165	Target Neighborhood Hits	219	Shared Neighborhood Hits	30
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

DLK_HUMAN
NC score	0.052813 (rank : 389)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	165	Target Neighborhood Hits	401	Shared Neighborhood Hits	41
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

KRA99_HUMAN
NC score	0.052725 (rank : 390)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	165	Target Neighborhood Hits	173	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

CHRD_MOUSE
NC score	0.052581 (rank : 391)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	165	Target Neighborhood Hits	102	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

ADA30_HUMAN
NC score	0.052558 (rank : 392)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	165	Target Neighborhood Hits	391	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

KRA55_HUMAN
NC score	0.052440 (rank : 393)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	165	Target Neighborhood Hits	257	Shared Neighborhood Hits	32
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

FSTL4_HUMAN
NC score	0.052340 (rank : 394)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	165	Target Neighborhood Hits	344	Shared Neighborhood Hits	18
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

GP124_MOUSE
NC score	0.052273 (rank : 395)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	165	Target Neighborhood Hits	423	Shared Neighborhood Hits	11
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

LCE1E_HUMAN
NC score	0.052268 (rank : 396)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	165	Target Neighborhood Hits	53	Shared Neighborhood Hits	10
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

VIPR2_MOUSE
NC score	0.052182 (rank : 397)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	165	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	P41588, P97750	Gene names	Vipr2
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3).

G7C_MOUSE
NC score	0.052147 (rank : 398)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	165	Target Neighborhood Hits	7	Shared Neighborhood Hits	1
SwissProt Accessions	Q9JHA8, Q9Z1Q8	Gene names	D17H6S56E-3, G7c
Domain Architecture	No domain graphic available
Description	Protein G7c precursor.

KRA52_HUMAN
NC score	0.051914 (rank : 399)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	165	Target Neighborhood Hits	236	Shared Neighborhood Hits	27
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

GRN_HUMAN
NC score	0.051552 (rank : 400)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	165	Target Neighborhood Hits	268	Shared Neighborhood Hits	29
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

LCE1F_HUMAN
NC score	0.051190 (rank : 401)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	165	Target Neighborhood Hits	48	Shared Neighborhood Hits	8
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

PROS_MOUSE
NC score	0.051169 (rank : 402)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	165	Target Neighborhood Hits	330	Shared Neighborhood Hits	26
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

EGFL9_HUMAN
NC score	0.051135 (rank : 403)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	165	Target Neighborhood Hits	365	Shared Neighborhood Hits	42
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

KRA57_HUMAN
NC score	0.051107 (rank : 404)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	165	Target Neighborhood Hits	269	Shared Neighborhood Hits	27
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

G7C_HUMAN
NC score	0.050871 (rank : 405)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	165	Target Neighborhood Hits	21	Shared Neighborhood Hits	1
SwissProt Accessions	Q9Y334, Q5SSR5, Q96QC8, Q9UMP9	Gene names	C6orf27, G7C, NG37
Domain Architecture	No domain graphic available
Description	Protein G7c precursor.

PROS_HUMAN
NC score	0.050860 (rank : 406)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	165	Target Neighborhood Hits	340	Shared Neighborhood Hits	26
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

KR410_HUMAN
NC score	0.050411 (rank : 407)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	165	Target Neighborhood Hits	156	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

FSTL5_HUMAN
NC score	0.050389 (rank : 408)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	165	Target Neighborhood Hits	347	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

VLDLR_MOUSE
NC score	0.050316 (rank : 409)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	165	Target Neighborhood Hits	360	Shared Neighborhood Hits	34
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

CDON_MOUSE
NC score	0.050120 (rank : 410)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	165	Target Neighborhood Hits	410	Shared Neighborhood Hits	17
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

CJ095_HUMAN
NC score	0.044011 (rank : 411)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	165	Target Neighborhood Hits	50	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H7T3	Gene names	C10orf95
Domain Architecture	No domain graphic available
Description	Protein C10orf95.

MK_MOUSE
NC score	0.041745 (rank : 412)	θ value	8.99809 (rank : 162)
Query Neighborhood Hits	165	Target Neighborhood Hits	21	Shared Neighborhood Hits	16
SwissProt Accessions	P12025	Gene names	Mdk, Mk
Domain Architecture
Description	Midkine precursor (MK) (Retinoic acid-induced differentiation factor).

TNR9_HUMAN
NC score	0.041046 (rank : 413)	θ value	0.21417 (rank : 94)
Query Neighborhood Hits	165	Target Neighborhood Hits	166	Shared Neighborhood Hits	18
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

MEGF9_HUMAN
NC score	0.040716 (rank : 414)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	165	Target Neighborhood Hits	557	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

ATRN_HUMAN
NC score	0.038344 (rank : 415)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	165	Target Neighborhood Hits	525	Shared Neighborhood Hits	38
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

LYAM2_MOUSE
NC score	0.037464 (rank : 416)	θ value	0.279714 (rank : 95)
Query Neighborhood Hits	165	Target Neighborhood Hits	420	Shared Neighborhood Hits	37
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

ATRN_MOUSE
NC score	0.036440 (rank : 417)	θ value	0.813845 (rank : 102)
Query Neighborhood Hits	165	Target Neighborhood Hits	519	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

LAMC1_HUMAN
NC score	0.036066 (rank : 418)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	165	Target Neighborhood Hits	922	Shared Neighborhood Hits	43
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMA3_MOUSE
NC score	0.032612 (rank : 419)	θ value	5.27518 (rank : 141)
Query Neighborhood Hits	165	Target Neighborhood Hits	859	Shared Neighborhood Hits	47
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

SPR2I_MOUSE
NC score	0.029803 (rank : 420)	θ value	8.99809 (rank : 164)
Query Neighborhood Hits	165	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

CF136_HUMAN
NC score	0.028691 (rank : 421)	θ value	3.0926 (rank : 125)
Query Neighborhood Hits	165	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q5SQH8, Q5SU01, Q6ZSB7, Q8TB84	Gene names	C6orf136
Domain Architecture	No domain graphic available
Description	Protein C6orf136.

CN032_HUMAN
NC score	0.026459 (rank : 422)	θ value	0.125558 (rank : 89)
Query Neighborhood Hits	165	Target Neighborhood Hits	267	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

ITB2_HUMAN
NC score	0.020989 (rank : 423)	θ value	5.27518 (rank : 140)
Query Neighborhood Hits	165	Target Neighborhood Hits	282	Shared Neighborhood Hits	28
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

TNR8_MOUSE
NC score	0.020837 (rank : 424)	θ value	8.99809 (rank : 165)
Query Neighborhood Hits	165	Target Neighborhood Hits	208	Shared Neighborhood Hits	19
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

ODFP_MOUSE
NC score	0.018742 (rank : 425)	θ value	6.88961 (rank : 150)
Query Neighborhood Hits	165	Target Neighborhood Hits	75	Shared Neighborhood Hits	14
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

ODFP_HUMAN
NC score	0.016684 (rank : 426)	θ value	5.27518 (rank : 142)
Query Neighborhood Hits	165	Target Neighborhood Hits	32	Shared Neighborhood Hits	6
SwissProt Accessions	Q14990	Gene names	ODF1, ODFP
Domain Architecture
Description	Outer dense fiber protein.

CIC_MOUSE
NC score	0.016132 (rank : 427)	θ value	0.813845 (rank : 103)
Query Neighborhood Hits	165	Target Neighborhood Hits	742	Shared Neighborhood Hits	21
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

TTDN1_HUMAN
NC score	0.015437 (rank : 428)	θ value	4.03905 (rank : 139)
Query Neighborhood Hits	165	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TAP9	Gene names	TTDN1, C7orf11
Domain Architecture	No domain graphic available
Description	TTD non-photosensitive 1 protein.

TB182_HUMAN
NC score	0.015365 (rank : 429)	θ value	5.27518 (rank : 144)
Query Neighborhood Hits	165	Target Neighborhood Hits	414	Shared Neighborhood Hits	8
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

TF7L1_MOUSE
NC score	0.013680 (rank : 430)	θ value	1.81305 (rank : 118)
Query Neighborhood Hits	165	Target Neighborhood Hits	131	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1J1, O70450, O70573	Gene names	Tcf7l1, Tcf3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF-3) (mTCF-3).

BORG5_HUMAN
NC score	0.013657 (rank : 431)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	165	Target Neighborhood Hits	135	Shared Neighborhood Hits	8
SwissProt Accessions	Q00587, Q96GN1	Gene names	CDC42EP1, BORG5, CEP1, MSE55
Domain Architecture
Description	Cdc42 effector protein 1 (Binder of Rho GTPases 5) (Serum protein MSE55).

TF7L1_HUMAN
NC score	0.013656 (rank : 432)	θ value	1.81305 (rank : 117)
Query Neighborhood Hits	165	Target Neighborhood Hits	129	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HCS4, Q53R97, Q6PD70, Q9NP00	Gene names	TCF7L1, TCF3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF- 3).

CN032_MOUSE
NC score	0.013495 (rank : 433)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	165	Target Neighborhood Hits	233	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CD2A2_HUMAN
NC score	0.013157 (rank : 434)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	165	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N726, Q13195, Q13399, Q16360, Q7KZR9	Gene names	CDKN2A
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase inhibitor 2A, isoform 4 (p14ARF) (p19ARF).

PCX3_MOUSE
NC score	0.012972 (rank : 435)	θ value	3.0926 (rank : 128)
Query Neighborhood Hits	165	Target Neighborhood Hits	134	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VI59	Gene names	Pcnxl3
Domain Architecture
Description	Pecanex-like protein 3.

WDR43_HUMAN
NC score	0.012493 (rank : 436)	θ value	0.813845 (rank : 107)
Query Neighborhood Hits	165	Target Neighborhood Hits	269	Shared Neighborhood Hits	4
SwissProt Accessions	Q15061, Q15395, Q92577	Gene names	WDR43, KIAA0007
Domain Architecture	No domain graphic available
Description	WD repeat protein 43.

ASPH_HUMAN
NC score	0.012159 (rank : 437)	θ value	4.03905 (rank : 135)
Query Neighborhood Hits	165	Target Neighborhood Hits	158	Shared Neighborhood Hits	2
SwissProt Accessions	Q12797	Gene names	ASPH
Domain Architecture
Description	Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta- hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta- dioxygenase).

ASXL1_MOUSE
NC score	0.012144 (rank : 438)	θ value	3.0926 (rank : 124)
Query Neighborhood Hits	165	Target Neighborhood Hits	182	Shared Neighborhood Hits	6
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

PRR13_HUMAN
NC score	0.012082 (rank : 439)	θ value	6.88961 (rank : 151)
Query Neighborhood Hits	165	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

JPH4_MOUSE
NC score	0.011975 (rank : 440)	θ value	0.813845 (rank : 105)
Query Neighborhood Hits	165	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	Q80WT0, Q8BMI1	Gene names	Jph4, Jphl1
Domain Architecture	No domain graphic available
Description	Junctophilin-4 (Junctophilin-like 1 protein).

NFAC1_HUMAN
NC score	0.011934 (rank : 441)	θ value	4.03905 (rank : 137)
Query Neighborhood Hits	165	Target Neighborhood Hits	312	Shared Neighborhood Hits	12
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

UBE4B_HUMAN
NC score	0.011004 (rank : 442)	θ value	3.0926 (rank : 132)
Query Neighborhood Hits	165	Target Neighborhood Hits	158	Shared Neighborhood Hits	5
SwissProt Accessions	O95155, O75169, O95338, Q5SZ12, Q5SZ16, Q96QD4, Q9BYI7	Gene names	UBE4B, HDNB1, KIAA0684, UFD2
Domain Architecture
Description	Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Homozygously deleted in neuroblastoma 1).

REXO1_HUMAN
NC score	0.008722 (rank : 443)	θ value	3.0926 (rank : 129)
Query Neighborhood Hits	165	Target Neighborhood Hits	242	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

NMDE3_HUMAN
NC score	0.008533 (rank : 444)	θ value	0.813845 (rank : 106)
Query Neighborhood Hits	165	Target Neighborhood Hits	110	Shared Neighborhood Hits	7
SwissProt Accessions	Q14957	Gene names	GRIN2C
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

CJ078_MOUSE
NC score	0.007391 (rank : 445)	θ value	1.81305 (rank : 114)
Query Neighborhood Hits	165	Target Neighborhood Hits	559	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CSKI2_HUMAN
NC score	0.007026 (rank : 446)	θ value	1.06291 (rank : 109)
Query Neighborhood Hits	165	Target Neighborhood Hits	747	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CIC_HUMAN
NC score	0.006918 (rank : 447)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	165	Target Neighborhood Hits	992	Shared Neighborhood Hits	18
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

HCN2_HUMAN
NC score	0.006897 (rank : 448)	θ value	0.813845 (rank : 104)
Query Neighborhood Hits	165	Target Neighborhood Hits	369	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

IRS2_MOUSE
NC score	0.006664 (rank : 449)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	165	Target Neighborhood Hits	248	Shared Neighborhood Hits	9
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

SFPQ_MOUSE
NC score	0.006379 (rank : 450)	θ value	3.0926 (rank : 131)
Query Neighborhood Hits	165	Target Neighborhood Hits	958	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

PKD1_HUMAN
NC score	0.006243 (rank : 451)	θ value	5.27518 (rank : 143)
Query Neighborhood Hits	165	Target Neighborhood Hits	387	Shared Neighborhood Hits	6
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

SFPQ_HUMAN
NC score	0.006222 (rank : 452)	θ value	3.0926 (rank : 130)
Query Neighborhood Hits	165	Target Neighborhood Hits	986	Shared Neighborhood Hits	11
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

HXA3_MOUSE
NC score	0.005521 (rank : 453)	θ value	0.47712 (rank : 99)
Query Neighborhood Hits	165	Target Neighborhood Hits	558	Shared Neighborhood Hits	7
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

ERBB3_HUMAN
NC score	0.005035 (rank : 454)	θ value	1.81305 (rank : 115)
Query Neighborhood Hits	165	Target Neighborhood Hits	918	Shared Neighborhood Hits	25
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

MAP1A_HUMAN
NC score	0.004550 (rank : 455)	θ value	3.0926 (rank : 127)
Query Neighborhood Hits	165	Target Neighborhood Hits	1626	Shared Neighborhood Hits	24
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

SYN1_MOUSE
NC score	0.004036 (rank : 456)	θ value	4.03905 (rank : 138)
Query Neighborhood Hits	165	Target Neighborhood Hits	363	Shared Neighborhood Hits	6
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

FA12_HUMAN
NC score	0.003871 (rank : 457)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	165	Target Neighborhood Hits	425	Shared Neighborhood Hits	18
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

DRD4_HUMAN
NC score	0.001702 (rank : 458)	θ value	0.125558 (rank : 90)
Query Neighborhood Hits	165	Target Neighborhood Hits	886	Shared Neighborhood Hits	9
SwissProt Accessions	P21917	Gene names	DRD4
Domain Architecture
Description	D(4) dopamine receptor (Dopamine D4 receptor) (D(2C) dopamine receptor).

CAC1C_HUMAN
NC score	0.001055 (rank : 459)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	165	Target Neighborhood Hits	158	Shared Neighborhood Hits	3
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

PDE6A_HUMAN
NC score	0.000965 (rank : 460)	θ value	8.99809 (rank : 163)
Query Neighborhood Hits	165	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	P16499	Gene names	PDE6A, PDEA
Domain Architecture
Description	Rod cGMP-specific 3',5'-cyclic phosphodiesterase alpha-subunit (EC 3.1.4.35) (GMP-PDE alpha) (PDE V-B1).

ERBB4_HUMAN
NC score	0.000539 (rank : 461)	θ value	4.03905 (rank : 136)
Query Neighborhood Hits	165	Target Neighborhood Hits	910	Shared Neighborhood Hits	21
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

RX_HUMAN
NC score	-0.001938 (rank : 462)	θ value	6.88961 (rank : 152)
Query Neighborhood Hits	165	Target Neighborhood Hits	423	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2V3	Gene names	RAX, RX
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

ADA1B_MOUSE
NC score	-0.005207 (rank : 463)	θ value	4.03905 (rank : 134)
Query Neighborhood Hits	165	Target Neighborhood Hits	966	Shared Neighborhood Hits	3
SwissProt Accessions	P97717	Gene names	Adra1b
Domain Architecture
Description	Alpha-1B adrenergic receptor (Alpha 1B-adrenoceptor) (Alpha 1B- adrenoreceptor).

ZEP1_MOUSE
NC score	-0.005308 (rank : 464)	θ value	6.88961 (rank : 153)
Query Neighborhood Hits	165	Target Neighborhood Hits	1063	Shared Neighborhood Hits	10
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

MTF1_HUMAN
NC score	-0.007135 (rank : 465)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	165	Target Neighborhood Hits	814	Shared Neighborhood Hits	4
SwissProt Accessions	Q14872, Q96CB1	Gene names	MTF1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).