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Network neighborhood for query Sequence : RSPO3_MOUSE

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RSPO3_MOUSE
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RSPO3_MOUSE
θ value	3.77839e-115 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	120	Target Neighborhood Hits	120	Shared Neighborhood Hits	120
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

RSPO3_HUMAN
θ value	8.71062e-112 (rank : 2)	NC score	0.991331 (rank : 2)
Query Neighborhood Hits	120	Target Neighborhood Hits	128	Shared Neighborhood Hits	100
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

RSPO1_HUMAN
θ value	3.71096e-62 (rank : 3)	NC score	0.953322 (rank : 3)
Query Neighborhood Hits	120	Target Neighborhood Hits	101	Shared Neighborhood Hits	67
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

RSPO1_MOUSE
θ value	1.19377e-60 (rank : 4)	NC score	0.952255 (rank : 4)
Query Neighborhood Hits	120	Target Neighborhood Hits	85	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

RSPO2_HUMAN
θ value	1.66964e-54 (rank : 5)	NC score	0.947329 (rank : 5)
Query Neighborhood Hits	120	Target Neighborhood Hits	90	Shared Neighborhood Hits	64
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

RSPO2_MOUSE
θ value	4.85792e-54 (rank : 6)	NC score	0.944932 (rank : 6)
Query Neighborhood Hits	120	Target Neighborhood Hits	88	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

RSPO4_HUMAN
θ value	3.61106e-41 (rank : 7)	NC score	0.918656 (rank : 7)
Query Neighborhood Hits	120	Target Neighborhood Hits	110	Shared Neighborhood Hits	60
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

RSPO4_MOUSE
θ value	6.81017e-40 (rank : 8)	NC score	0.914397 (rank : 8)
Query Neighborhood Hits	120	Target Neighborhood Hits	110	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

PCSK5_MOUSE
θ value	3.29651e-10 (rank : 9)	NC score	0.340799 (rank : 9)
Query Neighborhood Hits	120	Target Neighborhood Hits	613	Shared Neighborhood Hits	89
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

PCSK6_HUMAN
θ value	4.30538e-10 (rank : 10)	NC score	0.340776 (rank : 10)
Query Neighborhood Hits	120	Target Neighborhood Hits	298	Shared Neighborhood Hits	64
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

PCSK5_HUMAN
θ value	5.26297e-08 (rank : 11)	NC score	0.333171 (rank : 11)
Query Neighborhood Hits	120	Target Neighborhood Hits	291	Shared Neighborhood Hits	78
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

FRAS1_HUMAN
θ value	8.97725e-08 (rank : 12)	NC score	0.290835 (rank : 15)
Query Neighborhood Hits	120	Target Neighborhood Hits	759	Shared Neighborhood Hits	91
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FRAS1_MOUSE
θ value	7.59969e-07 (rank : 13)	NC score	0.291327 (rank : 13)
Query Neighborhood Hits	120	Target Neighborhood Hits	747	Shared Neighborhood Hits	91
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

SPON1_MOUSE
θ value	6.43352e-06 (rank : 14)	NC score	0.281926 (rank : 16)
Query Neighborhood Hits	120	Target Neighborhood Hits	123	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

INSRR_HUMAN
θ value	1.87187e-05 (rank : 15)	NC score	0.108943 (rank : 75)
Query Neighborhood Hits	120	Target Neighborhood Hits	950	Shared Neighborhood Hits	59
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

SPON1_HUMAN
θ value	2.44474e-05 (rank : 16)	NC score	0.280858 (rank : 17)
Query Neighborhood Hits	120	Target Neighborhood Hits	117	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

INSRR_MOUSE
θ value	5.44631e-05 (rank : 17)	NC score	0.106214 (rank : 83)
Query Neighborhood Hits	120	Target Neighborhood Hits	961	Shared Neighborhood Hits	60
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

IGF1R_MOUSE
θ value	9.29e-05 (rank : 18)	NC score	0.106177 (rank : 84)
Query Neighborhood Hits	120	Target Neighborhood Hits	973	Shared Neighborhood Hits	59
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IGF1R_HUMAN
θ value	0.00035302 (rank : 19)	NC score	0.103690 (rank : 87)
Query Neighborhood Hits	120	Target Neighborhood Hits	977	Shared Neighborhood Hits	53
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

INSR_HUMAN
θ value	0.000786445 (rank : 20)	NC score	0.097863 (rank : 105)
Query Neighborhood Hits	120	Target Neighborhood Hits	963	Shared Neighborhood Hits	49
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

INSR_MOUSE
θ value	0.00102713 (rank : 21)	NC score	0.099665 (rank : 99)
Query Neighborhood Hits	120	Target Neighborhood Hits	968	Shared Neighborhood Hits	48
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

SPON2_HUMAN
θ value	0.00390308 (rank : 22)	NC score	0.300072 (rank : 12)
Query Neighborhood Hits	120	Target Neighborhood Hits	53	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BUD6, Q9ULW1	Gene names	SPON2, DIL1
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin) (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1).

TNR6B_HUMAN
θ value	0.00509761 (rank : 23)	NC score	0.144336 (rank : 27)
Query Neighborhood Hits	120	Target Neighborhood Hits	103	Shared Neighborhood Hits	24
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

HMCN1_HUMAN
θ value	0.00665767 (rank : 24)	NC score	0.118752 (rank : 54)
Query Neighborhood Hits	120	Target Neighborhood Hits	983	Shared Neighborhood Hits	86
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

NOTC2_HUMAN
θ value	0.00869519 (rank : 25)	NC score	0.104761 (rank : 86)
Query Neighborhood Hits	120	Target Neighborhood Hits	1113	Shared Neighborhood Hits	70
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

SPON2_MOUSE
θ value	0.0148317 (rank : 26)	NC score	0.291184 (rank : 14)
Query Neighborhood Hits	120	Target Neighborhood Hits	42	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).

BAI2_HUMAN
θ value	0.0252991 (rank : 27)	NC score	0.142287 (rank : 31)
Query Neighborhood Hits	120	Target Neighborhood Hits	332	Shared Neighborhood Hits	41
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_MOUSE
θ value	0.0252991 (rank : 28)	NC score	0.141472 (rank : 32)
Query Neighborhood Hits	120	Target Neighborhood Hits	323	Shared Neighborhood Hits	42
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

CREL1_HUMAN
θ value	0.0431538 (rank : 29)	NC score	0.170036 (rank : 24)
Query Neighborhood Hits	120	Target Neighborhood Hits	441	Shared Neighborhood Hits	60
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

SREC2_MOUSE
θ value	0.0431538 (rank : 30)	NC score	0.143947 (rank : 29)
Query Neighborhood Hits	120	Target Neighborhood Hits	605	Shared Neighborhood Hits	72
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

LTBP2_MOUSE
θ value	0.0563607 (rank : 31)	NC score	0.129302 (rank : 40)
Query Neighborhood Hits	120	Target Neighborhood Hits	617	Shared Neighborhood Hits	68
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

NELL1_HUMAN
θ value	0.0736092 (rank : 32)	NC score	0.126822 (rank : 41)
Query Neighborhood Hits	120	Target Neighborhood Hits	451	Shared Neighborhood Hits	65
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NOTC1_HUMAN
θ value	0.0736092 (rank : 33)	NC score	0.112553 (rank : 63)
Query Neighborhood Hits	120	Target Neighborhood Hits	906	Shared Neighborhood Hits	72
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

BAI1_HUMAN
θ value	0.0961366 (rank : 34)	NC score	0.130415 (rank : 39)
Query Neighborhood Hits	120	Target Neighborhood Hits	375	Shared Neighborhood Hits	42
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_MOUSE
θ value	0.0961366 (rank : 35)	NC score	0.124244 (rank : 46)
Query Neighborhood Hits	120	Target Neighborhood Hits	340	Shared Neighborhood Hits	37
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

SSPO_MOUSE
θ value	0.0961366 (rank : 36)	NC score	0.179572 (rank : 19)
Query Neighborhood Hits	120	Target Neighborhood Hits	800	Shared Neighborhood Hits	93
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

CREL1_MOUSE
θ value	0.125558 (rank : 37)	NC score	0.172853 (rank : 22)
Query Neighborhood Hits	120	Target Neighborhood Hits	524	Shared Neighborhood Hits	64
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

NOTC1_MOUSE
θ value	0.125558 (rank : 38)	NC score	0.112835 (rank : 61)
Query Neighborhood Hits	120	Target Neighborhood Hits	916	Shared Neighborhood Hits	69
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

FBN1_HUMAN
θ value	0.163984 (rank : 39)	NC score	0.131710 (rank : 37)
Query Neighborhood Hits	120	Target Neighborhood Hits	557	Shared Neighborhood Hits	76
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_MOUSE
θ value	0.163984 (rank : 40)	NC score	0.130470 (rank : 38)
Query Neighborhood Hits	120	Target Neighborhood Hits	563	Shared Neighborhood Hits	71
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

ATRX_HUMAN
θ value	0.21417 (rank : 41)	NC score	0.018997 (rank : 361)
Query Neighborhood Hits	120	Target Neighborhood Hits	842	Shared Neighborhood Hits	10
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

ERBB3_MOUSE
θ value	0.21417 (rank : 42)	NC score	0.064166 (rank : 253)
Query Neighborhood Hits	120	Target Neighborhood Hits	898	Shared Neighborhood Hits	45
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

ATS16_MOUSE
θ value	0.279714 (rank : 43)	NC score	0.081507 (rank : 157)
Query Neighborhood Hits	120	Target Neighborhood Hits	179	Shared Neighborhood Hits	38
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

FURIN_MOUSE
θ value	0.279714 (rank : 44)	NC score	0.175785 (rank : 21)
Query Neighborhood Hits	120	Target Neighborhood Hits	49	Shared Neighborhood Hits	25
SwissProt Accessions	P23188	Gene names	Furin, Fur, Pcsk3
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme) (Prohormone convertase 3).

MEGF6_HUMAN
θ value	0.279714 (rank : 45)	NC score	0.145695 (rank : 25)
Query Neighborhood Hits	120	Target Neighborhood Hits	671	Shared Neighborhood Hits	86
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

TIE2_MOUSE
θ value	0.279714 (rank : 46)	NC score	0.059058 (rank : 274)
Query Neighborhood Hits	120	Target Neighborhood Hits	1204	Shared Neighborhood Hits	67
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

BMPER_HUMAN
θ value	0.365318 (rank : 47)	NC score	0.117388 (rank : 56)
Query Neighborhood Hits	120	Target Neighborhood Hits	175	Shared Neighborhood Hits	42
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

FURIN_HUMAN
θ value	0.365318 (rank : 48)	NC score	0.178969 (rank : 20)
Query Neighborhood Hits	120	Target Neighborhood Hits	52	Shared Neighborhood Hits	24
SwissProt Accessions	P09958, Q14336, Q6LBS3	Gene names	FURIN, FUR, PACE
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme).

PROP_MOUSE
θ value	0.365318 (rank : 49)	NC score	0.182787 (rank : 18)
Query Neighborhood Hits	120	Target Neighborhood Hits	165	Shared Neighborhood Hits	42
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

TSP1_HUMAN
θ value	0.365318 (rank : 50)	NC score	0.144063 (rank : 28)
Query Neighborhood Hits	120	Target Neighborhood Hits	389	Shared Neighborhood Hits	76
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP2_MOUSE
θ value	0.365318 (rank : 51)	NC score	0.136442 (rank : 35)
Query Neighborhood Hits	120	Target Neighborhood Hits	352	Shared Neighborhood Hits	71
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

DLL4_HUMAN
θ value	0.47712 (rank : 52)	NC score	0.095005 (rank : 110)
Query Neighborhood Hits	120	Target Neighborhood Hits	435	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

PROP_HUMAN
θ value	0.47712 (rank : 53)	NC score	0.170666 (rank : 23)
Query Neighborhood Hits	120	Target Neighborhood Hits	126	Shared Neighborhood Hits	43
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

SREC2_HUMAN
θ value	0.47712 (rank : 54)	NC score	0.143110 (rank : 30)
Query Neighborhood Hits	120	Target Neighborhood Hits	645	Shared Neighborhood Hits	70
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

TR11B_HUMAN
θ value	0.47712 (rank : 55)	NC score	0.073200 (rank : 202)
Query Neighborhood Hits	120	Target Neighborhood Hits	92	Shared Neighborhood Hits	16
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

ERBB3_HUMAN
θ value	0.62314 (rank : 56)	NC score	0.063023 (rank : 256)
Query Neighborhood Hits	120	Target Neighborhood Hits	918	Shared Neighborhood Hits	46
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

LAMA5_HUMAN
θ value	0.62314 (rank : 57)	NC score	0.090898 (rank : 123)
Query Neighborhood Hits	120	Target Neighborhood Hits	976	Shared Neighborhood Hits	79
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

DLL4_MOUSE
θ value	0.813845 (rank : 58)	NC score	0.097630 (rank : 107)
Query Neighborhood Hits	120	Target Neighborhood Hits	440	Shared Neighborhood Hits	59
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

EPHB2_HUMAN
θ value	0.813845 (rank : 59)	NC score	0.035593 (rank : 351)
Query Neighborhood Hits	120	Target Neighborhood Hits	983	Shared Neighborhood Hits	31
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB2_MOUSE
θ value	0.813845 (rank : 60)	NC score	0.035573 (rank : 352)
Query Neighborhood Hits	120	Target Neighborhood Hits	982	Shared Neighborhood Hits	31
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

LTBP4_MOUSE
θ value	0.813845 (rank : 61)	NC score	0.132569 (rank : 36)
Query Neighborhood Hits	120	Target Neighborhood Hits	607	Shared Neighborhood Hits	70
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

TSP1_MOUSE
θ value	0.813845 (rank : 62)	NC score	0.144534 (rank : 26)
Query Neighborhood Hits	120	Target Neighborhood Hits	396	Shared Neighborhood Hits	76
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

WIF1_HUMAN
θ value	0.813845 (rank : 63)	NC score	0.113343 (rank : 60)
Query Neighborhood Hits	120	Target Neighborhood Hits	392	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_MOUSE
θ value	0.813845 (rank : 64)	NC score	0.114889 (rank : 58)
Query Neighborhood Hits	120	Target Neighborhood Hits	393	Shared Neighborhood Hits	59
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

FBLN3_HUMAN
θ value	1.06291 (rank : 65)	NC score	0.094452 (rank : 112)
Query Neighborhood Hits	120	Target Neighborhood Hits	293	Shared Neighborhood Hits	54
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBN2_MOUSE
θ value	1.06291 (rank : 66)	NC score	0.122273 (rank : 50)
Query Neighborhood Hits	120	Target Neighborhood Hits	549	Shared Neighborhood Hits	69
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

HIRP3_HUMAN
θ value	1.06291 (rank : 67)	NC score	0.028505 (rank : 355)
Query Neighborhood Hits	120	Target Neighborhood Hits	323	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

LTB1S_MOUSE
θ value	1.06291 (rank : 68)	NC score	0.116470 (rank : 57)
Query Neighborhood Hits	120	Target Neighborhood Hits	479	Shared Neighborhood Hits	66
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

NOTC4_HUMAN
θ value	1.38821 (rank : 69)	NC score	0.097662 (rank : 106)
Query Neighborhood Hits	120	Target Neighborhood Hits	905	Shared Neighborhood Hits	72
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

SREC_HUMAN
θ value	1.38821 (rank : 70)	NC score	0.140655 (rank : 33)
Query Neighborhood Hits	120	Target Neighborhood Hits	645	Shared Neighborhood Hits	76
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

TNR5_MOUSE
θ value	1.38821 (rank : 71)	NC score	0.100350 (rank : 94)
Query Neighborhood Hits	120	Target Neighborhood Hits	131	Shared Neighborhood Hits	31
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

BAI3_HUMAN
θ value	1.81305 (rank : 72)	NC score	0.126510 (rank : 42)
Query Neighborhood Hits	120	Target Neighborhood Hits	246	Shared Neighborhood Hits	43
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
θ value	1.81305 (rank : 73)	NC score	0.126043 (rank : 44)
Query Neighborhood Hits	120	Target Neighborhood Hits	250	Shared Neighborhood Hits	41
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

CILP1_HUMAN
θ value	1.81305 (rank : 74)	NC score	0.088908 (rank : 128)
Query Neighborhood Hits	120	Target Neighborhood Hits	266	Shared Neighborhood Hits	37
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

DLL3_MOUSE
θ value	1.81305 (rank : 75)	NC score	0.090270 (rank : 125)
Query Neighborhood Hits	120	Target Neighborhood Hits	399	Shared Neighborhood Hits	55
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

FBN2_HUMAN
θ value	1.81305 (rank : 76)	NC score	0.122574 (rank : 49)
Query Neighborhood Hits	120	Target Neighborhood Hits	560	Shared Neighborhood Hits	67
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

TSP2_HUMAN
θ value	1.81305 (rank : 77)	NC score	0.137619 (rank : 34)
Query Neighborhood Hits	120	Target Neighborhood Hits	359	Shared Neighborhood Hits	74
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

ATS20_MOUSE
θ value	2.36792 (rank : 78)	NC score	0.079595 (rank : 166)
Query Neighborhood Hits	120	Target Neighborhood Hits	225	Shared Neighborhood Hits	44
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

CO6_HUMAN
θ value	2.36792 (rank : 79)	NC score	0.078206 (rank : 175)
Query Neighborhood Hits	120	Target Neighborhood Hits	331	Shared Neighborhood Hits	48
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CTTB2_HUMAN
θ value	2.36792 (rank : 80)	NC score	0.010049 (rank : 365)
Query Neighborhood Hits	120	Target Neighborhood Hits	1061	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

LTB1L_HUMAN
θ value	2.36792 (rank : 81)	NC score	0.110427 (rank : 69)
Query Neighborhood Hits	120	Target Neighborhood Hits	553	Shared Neighborhood Hits	64
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	2.36792 (rank : 82)	NC score	0.110684 (rank : 68)
Query Neighborhood Hits	120	Target Neighborhood Hits	502	Shared Neighborhood Hits	63
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MRCKB_HUMAN
θ value	2.36792 (rank : 83)	NC score	0.006117 (rank : 369)
Query Neighborhood Hits	120	Target Neighborhood Hits	2239	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

C1QR1_HUMAN
θ value	3.0926 (rank : 84)	NC score	0.100252 (rank : 95)
Query Neighborhood Hits	120	Target Neighborhood Hits	493	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

ERBB4_HUMAN
θ value	3.0926 (rank : 85)	NC score	0.054220 (rank : 314)
Query Neighborhood Hits	120	Target Neighborhood Hits	910	Shared Neighborhood Hits	41
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

IDLC_HUMAN
θ value	3.0926 (rank : 86)	NC score	0.024066 (rank : 357)
Query Neighborhood Hits	120	Target Neighborhood Hits	348	Shared Neighborhood Hits	6
SwissProt Accessions	O14645, Q5TGH0, Q7L0I5	Gene names	DNALI1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal) (hp28).

IDLC_MOUSE
θ value	3.0926 (rank : 87)	NC score	0.023905 (rank : 358)
Query Neighborhood Hits	120	Target Neighborhood Hits	321	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BVN8	Gene names	Dnali1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal).

LTBP2_HUMAN
θ value	3.0926 (rank : 88)	NC score	0.117541 (rank : 55)
Query Neighborhood Hits	120	Target Neighborhood Hits	552	Shared Neighborhood Hits	69
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

VEGFD_HUMAN
θ value	3.0926 (rank : 89)	NC score	0.034396 (rank : 353)
Query Neighborhood Hits	120	Target Neighborhood Hits	48	Shared Neighborhood Hits	9
SwissProt Accessions	O43915	Gene names	FIGF, VEGFD
Domain Architecture
Description	Vascular endothelial growth factor D precursor (VEGF-D) (c-fos-induced growth factor) (FIGF).

ATS20_HUMAN
θ value	4.03905 (rank : 90)	NC score	0.072292 (rank : 208)
Query Neighborhood Hits	120	Target Neighborhood Hits	192	Shared Neighborhood Hits	41
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS3_HUMAN
θ value	4.03905 (rank : 91)	NC score	0.053069 (rank : 322)
Query Neighborhood Hits	120	Target Neighborhood Hits	179	Shared Neighborhood Hits	37
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

FBLN2_MOUSE
θ value	4.03905 (rank : 92)	NC score	0.099253 (rank : 100)
Query Neighborhood Hits	120	Target Neighborhood Hits	505	Shared Neighborhood Hits	60
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

LDLR_HUMAN
θ value	4.03905 (rank : 93)	NC score	0.070737 (rank : 213)
Query Neighborhood Hits	120	Target Neighborhood Hits	375	Shared Neighborhood Hits	57
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LHX4_HUMAN
θ value	4.03905 (rank : 94)	NC score	0.019803 (rank : 360)
Query Neighborhood Hits	120	Target Neighborhood Hits	455	Shared Neighborhood Hits	10
SwissProt Accessions	Q969G2, Q8NHE0, Q8TCJ1, Q8WWX2, Q969W2	Gene names	LHX4
Domain Architecture
Description	LIM/homeobox protein Lhx4.

LHX4_MOUSE
θ value	4.03905 (rank : 95)	NC score	0.019811 (rank : 359)
Query Neighborhood Hits	120	Target Neighborhood Hits	457	Shared Neighborhood Hits	10
SwissProt Accessions	P53776, O08916, Q9R280	Gene names	Lhx4, Gsh-4, Gsh4
Domain Architecture
Description	LIM/homeobox protein Lhx4.

MDC1_HUMAN
θ value	4.03905 (rank : 96)	NC score	0.010149 (rank : 363)
Query Neighborhood Hits	120	Target Neighborhood Hits	1446	Shared Neighborhood Hits	18
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MEGF9_HUMAN
θ value	4.03905 (rank : 97)	NC score	0.103122 (rank : 89)
Query Neighborhood Hits	120	Target Neighborhood Hits	557	Shared Neighborhood Hits	66
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

ZC11A_MOUSE
θ value	4.03905 (rank : 98)	NC score	0.016065 (rank : 362)
Query Neighborhood Hits	120	Target Neighborhood Hits	216	Shared Neighborhood Hits	5
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

ATS16_HUMAN
θ value	5.27518 (rank : 99)	NC score	0.073371 (rank : 200)
Query Neighborhood Hits	120	Target Neighborhood Hits	208	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ITB3_HUMAN
θ value	5.27518 (rank : 100)	NC score	0.066389 (rank : 238)
Query Neighborhood Hits	120	Target Neighborhood Hits	325	Shared Neighborhood Hits	59
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

LHX3_HUMAN
θ value	5.27518 (rank : 101)	NC score	0.007713 (rank : 367)
Query Neighborhood Hits	120	Target Neighborhood Hits	474	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UBR4, Q9NZB5, Q9P0I8, Q9P0I9	Gene names	LHX3
Domain Architecture
Description	LIM/homeobox protein Lhx3.

CCD55_HUMAN
θ value	6.88961 (rank : 102)	NC score	0.007552 (rank : 368)
Query Neighborhood Hits	120	Target Neighborhood Hits	513	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

EGFR_MOUSE
θ value	6.88961 (rank : 103)	NC score	0.054075 (rank : 317)
Query Neighborhood Hits	120	Target Neighborhood Hits	927	Shared Neighborhood Hits	46
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

FBLN3_MOUSE
θ value	6.88961 (rank : 104)	NC score	0.087281 (rank : 137)
Query Neighborhood Hits	120	Target Neighborhood Hits	279	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

ITB3_MOUSE
θ value	6.88961 (rank : 105)	NC score	0.064344 (rank : 250)
Query Neighborhood Hits	120	Target Neighborhood Hits	319	Shared Neighborhood Hits	50
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

LAMA1_HUMAN
θ value	6.88961 (rank : 106)	NC score	0.081243 (rank : 159)
Query Neighborhood Hits	120	Target Neighborhood Hits	804	Shared Neighborhood Hits	70
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

MEGF9_MOUSE
θ value	6.88961 (rank : 107)	NC score	0.101927 (rank : 91)
Query Neighborhood Hits	120	Target Neighborhood Hits	896	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MRCKB_MOUSE
θ value	6.88961 (rank : 108)	NC score	0.005621 (rank : 370)
Query Neighborhood Hits	120	Target Neighborhood Hits	2180	Shared Neighborhood Hits	25
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

VEGFD_MOUSE
θ value	6.88961 (rank : 109)	NC score	0.025064 (rank : 356)
Query Neighborhood Hits	120	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	P97946	Gene names	Figf, Vegfd
Domain Architecture
Description	Vascular endothelial growth factor D precursor (VEGF-D) (c-fos-induced growth factor) (FIGF).

VWF_MOUSE
θ value	6.88961 (rank : 110)	NC score	0.088318 (rank : 132)
Query Neighborhood Hits	120	Target Neighborhood Hits	381	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ATBF1_HUMAN
θ value	8.99809 (rank : 111)	NC score	0.001452 (rank : 372)
Query Neighborhood Hits	120	Target Neighborhood Hits	1547	Shared Neighborhood Hits	11
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

ATBF1_MOUSE
θ value	8.99809 (rank : 112)	NC score	0.002025 (rank : 371)
Query Neighborhood Hits	120	Target Neighborhood Hits	1841	Shared Neighborhood Hits	18
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CILP2_HUMAN
θ value	8.99809 (rank : 113)	NC score	0.086216 (rank : 144)
Query Neighborhood Hits	120	Target Neighborhood Hits	307	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

CJ078_MOUSE
θ value	8.99809 (rank : 114)	NC score	0.009127 (rank : 366)
Query Neighborhood Hits	120	Target Neighborhood Hits	559	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

LAMA2_HUMAN
θ value	8.99809 (rank : 115)	NC score	0.076198 (rank : 185)
Query Neighborhood Hits	120	Target Neighborhood Hits	1092	Shared Neighborhood Hits	72
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LTB1L_MOUSE
θ value	8.99809 (rank : 116)	NC score	0.112683 (rank : 62)
Query Neighborhood Hits	120	Target Neighborhood Hits	514	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

NEIL1_MOUSE
θ value	8.99809 (rank : 117)	NC score	0.010094 (rank : 364)
Query Neighborhood Hits	120	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K4Q6, Q80V58, Q9CYT9	Gene names	Neil1, Nei1
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 1 (EC 3.2.2.-) (EC 4.2.99.18) (Nei-like 1) (DNA glycosylase/AP lyase Neil1) (DNA-(apurinic or apyrimidinic site) lyase Neil1) (NEH1).

SCUB3_MOUSE
θ value	8.99809 (rank : 118)	NC score	0.113543 (rank : 59)
Query Neighborhood Hits	120	Target Neighborhood Hits	442	Shared Neighborhood Hits	65
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

TNR22_MOUSE
θ value	8.99809 (rank : 119)	NC score	0.049040 (rank : 350)
Query Neighborhood Hits	120	Target Neighborhood Hits	97	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

WISP1_HUMAN
θ value	8.99809 (rank : 120)	NC score	0.034215 (rank : 354)
Query Neighborhood Hits	120	Target Neighborhood Hits	121	Shared Neighborhood Hits	31
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

AGRIN_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.071937 (rank : 209)
Query Neighborhood Hits	120	Target Neighborhood Hits	582	Shared Neighborhood Hits	62
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

ATL2_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.065467 (rank : 245)
Query Neighborhood Hits	120	Target Neighborhood Hits	125	Shared Neighborhood Hits	32
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

ATL2_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.066566 (rank : 236)
Query Neighborhood Hits	120	Target Neighborhood Hits	137	Shared Neighborhood Hits	33
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

ATL3_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.056944 (rank : 291)
Query Neighborhood Hits	120	Target Neighborhood Hits	414	Shared Neighborhood Hits	37
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

ATL5_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.055164 (rank : 302)
Query Neighborhood Hits	120	Target Neighborhood Hits	103	Shared Neighborhood Hits	25
SwissProt Accessions	Q6ZMM2, Q8IW95	Gene names	ADAMTSL5, THSD6
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 5 precursor (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6).

ATRN_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.051047 (rank : 339)
Query Neighborhood Hits	120	Target Neighborhood Hits	519	Shared Neighborhood Hits	52
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

ATS12_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.056192 (rank : 293)
Query Neighborhood Hits	120	Target Neighborhood Hits	251	Shared Neighborhood Hits	32
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS12_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.058508 (rank : 280)
Query Neighborhood Hits	120	Target Neighborhood Hits	220	Shared Neighborhood Hits	33
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS13_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.053802 (rank : 318)
Query Neighborhood Hits	120	Target Neighborhood Hits	238	Shared Neighborhood Hits	32
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS13_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.052734 (rank : 326)
Query Neighborhood Hits	120	Target Neighborhood Hits	227	Shared Neighborhood Hits	36
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS17_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.070544 (rank : 214)
Query Neighborhood Hits	120	Target Neighborhood Hits	194	Shared Neighborhood Hits	40
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

ATS18_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.056154 (rank : 294)
Query Neighborhood Hits	120	Target Neighborhood Hits	169	Shared Neighborhood Hits	33
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS18_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.054916 (rank : 306)
Query Neighborhood Hits	120	Target Neighborhood Hits	163	Shared Neighborhood Hits	30
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS19_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.050546 (rank : 346)
Query Neighborhood Hits	120	Target Neighborhood Hits	203	Shared Neighborhood Hits	29
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS19_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.054270 (rank : 313)
Query Neighborhood Hits	120	Target Neighborhood Hits	188	Shared Neighborhood Hits	29
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS2_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.052396 (rank : 330)
Query Neighborhood Hits	120	Target Neighborhood Hits	179	Shared Neighborhood Hits	34
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS9_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.067733 (rank : 227)
Query Neighborhood Hits	120	Target Neighborhood Hits	219	Shared Neighborhood Hits	39
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

BMPER_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.098206 (rank : 104)
Query Neighborhood Hits	120	Target Neighborhood Hits	194	Shared Neighborhood Hits	45
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

C1QR1_MOUSE
θ value	θ > 10 (rank : 139)	NC score	0.089229 (rank : 126)
Query Neighborhood Hits	120	Target Neighborhood Hits	342	Shared Neighborhood Hits	55
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

CD248_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.054387 (rank : 312)
Query Neighborhood Hits	120	Target Neighborhood Hits	679	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD248_MOUSE
θ value	θ > 10 (rank : 141)	NC score	0.052674 (rank : 327)
Query Neighborhood Hits	120	Target Neighborhood Hits	578	Shared Neighborhood Hits	42
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD97_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.076482 (rank : 183)
Query Neighborhood Hits	120	Target Neighborhood Hits	353	Shared Neighborhood Hits	52
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CD97_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.066204 (rank : 239)
Query Neighborhood Hits	120	Target Neighborhood Hits	295	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CHRD_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.050869 (rank : 342)
Query Neighborhood Hits	120	Target Neighborhood Hits	102	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

CI094_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.052890 (rank : 323)
Query Neighborhood Hits	120	Target Neighborhood Hits	310	Shared Neighborhood Hits	29
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

CILP1_MOUSE
θ value	θ > 10 (rank : 146)	NC score	0.069066 (rank : 220)
Query Neighborhood Hits	120	Target Neighborhood Hits	282	Shared Neighborhood Hits	32
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CO7_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.059687 (rank : 271)
Query Neighborhood Hits	120	Target Neighborhood Hits	278	Shared Neighborhood Hits	48
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO8B_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.064035 (rank : 255)
Query Neighborhood Hits	120	Target Neighborhood Hits	199	Shared Neighborhood Hits	38
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO8B_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.068395 (rank : 223)
Query Neighborhood Hits	120	Target Neighborhood Hits	224	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

COMP_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.080920 (rank : 162)
Query Neighborhood Hits	120	Target Neighborhood Hits	258	Shared Neighborhood Hits	47
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

COMP_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.081007 (rank : 161)
Query Neighborhood Hits	120	Target Neighborhood Hits	290	Shared Neighborhood Hits	49
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CRIM1_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.125272 (rank : 45)
Query Neighborhood Hits	120	Target Neighborhood Hits	362	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

CRUM1_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.080715 (rank : 163)
Query Neighborhood Hits	120	Target Neighborhood Hits	457	Shared Neighborhood Hits	53
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM1_MOUSE
θ value	θ > 10 (rank : 154)	NC score	0.083105 (rank : 150)
Query Neighborhood Hits	120	Target Neighborhood Hits	444	Shared Neighborhood Hits	54
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CRUM2_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.082827 (rank : 152)
Query Neighborhood Hits	120	Target Neighborhood Hits	453	Shared Neighborhood Hits	59
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

CUBN_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.074108 (rank : 197)
Query Neighborhood Hits	120	Target Neighborhood Hits	482	Shared Neighborhood Hits	56
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CUBN_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.076011 (rank : 186)
Query Neighborhood Hits	120	Target Neighborhood Hits	477	Shared Neighborhood Hits	58
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

DLK_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.078072 (rank : 177)
Query Neighborhood Hits	120	Target Neighborhood Hits	401	Shared Neighborhood Hits	56
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLK_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.078635 (rank : 170)
Query Neighborhood Hits	120	Target Neighborhood Hits	374	Shared Neighborhood Hits	51
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

DLL1_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.086922 (rank : 141)
Query Neighborhood Hits	120	Target Neighborhood Hits	455	Shared Neighborhood Hits	58
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DLL1_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.087686 (rank : 134)
Query Neighborhood Hits	120	Target Neighborhood Hits	456	Shared Neighborhood Hits	61
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

DLL3_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.084938 (rank : 147)
Query Neighborhood Hits	120	Target Neighborhood Hits	419	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DNER_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.081898 (rank : 156)
Query Neighborhood Hits	120	Target Neighborhood Hits	460	Shared Neighborhood Hits	54
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DNER_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.078216 (rank : 174)
Query Neighborhood Hits	120	Target Neighborhood Hits	413	Shared Neighborhood Hits	53
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

EGFL7_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.066445 (rank : 237)
Query Neighborhood Hits	120	Target Neighborhood Hits	325	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL7_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.066588 (rank : 235)
Query Neighborhood Hits	120	Target Neighborhood Hits	287	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EGFL8_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.061403 (rank : 261)
Query Neighborhood Hits	120	Target Neighborhood Hits	270	Shared Neighborhood Hits	39
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL8_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.059578 (rank : 272)
Query Neighborhood Hits	120	Target Neighborhood Hits	266	Shared Neighborhood Hits	39
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EGFL9_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.082884 (rank : 151)
Query Neighborhood Hits	120	Target Neighborhood Hits	365	Shared Neighborhood Hits	56
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.081493 (rank : 158)
Query Neighborhood Hits	120	Target Neighborhood Hits	379	Shared Neighborhood Hits	54
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

EGFR_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.050675 (rank : 343)
Query Neighborhood Hits	120	Target Neighborhood Hits	939	Shared Neighborhood Hits	41
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

EGF_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.069484 (rank : 218)
Query Neighborhood Hits	120	Target Neighborhood Hits	343	Shared Neighborhood Hits	55
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EGF_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.068615 (rank : 222)
Query Neighborhood Hits	120	Target Neighborhood Hits	358	Shared Neighborhood Hits	54
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

ELTD1_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.055620 (rank : 298)
Query Neighborhood Hits	120	Target Neighborhood Hits	269	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

ELTD1_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.066867 (rank : 232)
Query Neighborhood Hits	120	Target Neighborhood Hits	288	Shared Neighborhood Hits	46
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

EMR1_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.082689 (rank : 153)
Query Neighborhood Hits	120	Target Neighborhood Hits	382	Shared Neighborhood Hits	58
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EMR1_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.079181 (rank : 168)
Query Neighborhood Hits	120	Target Neighborhood Hits	349	Shared Neighborhood Hits	48
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EMR2_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.075235 (rank : 191)
Query Neighborhood Hits	120	Target Neighborhood Hits	345	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

FBLN1_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.103293 (rank : 88)
Query Neighborhood Hits	120	Target Neighborhood Hits	324	Shared Neighborhood Hits	53
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN1_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.101576 (rank : 93)
Query Neighborhood Hits	120	Target Neighborhood Hits	329	Shared Neighborhood Hits	58
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN2_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.098486 (rank : 103)
Query Neighborhood Hits	120	Target Neighborhood Hits	392	Shared Neighborhood Hits	55
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN4_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.088084 (rank : 133)
Query Neighborhood Hits	120	Target Neighborhood Hits	278	Shared Neighborhood Hits	48
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.092016 (rank : 120)
Query Neighborhood Hits	120	Target Neighborhood Hits	270	Shared Neighborhood Hits	50
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.102006 (rank : 90)
Query Neighborhood Hits	120	Target Neighborhood Hits	329	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.105148 (rank : 85)
Query Neighborhood Hits	120	Target Neighborhood Hits	317	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBN3_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.121145 (rank : 52)
Query Neighborhood Hits	120	Target Neighborhood Hits	543	Shared Neighborhood Hits	62
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FREM2_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.058127 (rank : 283)
Query Neighborhood Hits	120	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q5SZK8, Q4QQG1, Q5H9N8, Q5T6Q1, Q6N057, Q6ZSB4, Q7Z305, Q7Z341	Gene names	FREM2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog).

FREM2_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.058540 (rank : 278)
Query Neighborhood Hits	120	Target Neighborhood Hits	73	Shared Neighborhood Hits	2
SwissProt Accessions	Q6NVD0, Q4W2Q5, Q5H8C0, Q811G9, Q8C4G5, Q8CD46	Gene names	Frem2, Nv1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog) (NV domain-containing protein 1).

FREM3_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.051187 (rank : 338)
Query Neighborhood Hits	120	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	P0C091	Gene names	FREM3
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor.

FREM3_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.050908 (rank : 341)
Query Neighborhood Hits	120	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q5H8B9	Gene names	Frem3, Nv2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor (NV domain- containing protein 2).

GAS6_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.066913 (rank : 231)
Query Neighborhood Hits	120	Target Neighborhood Hits	348	Shared Neighborhood Hits	50
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GAS6_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.066733 (rank : 233)
Query Neighborhood Hits	120	Target Neighborhood Hits	343	Shared Neighborhood Hits	50
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GRN_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.074345 (rank : 194)
Query Neighborhood Hits	120	Target Neighborhood Hits	268	Shared Neighborhood Hits	44
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

GRN_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.075871 (rank : 187)
Query Neighborhood Hits	120	Target Neighborhood Hits	248	Shared Neighborhood Hits	42
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

HHIP_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.057454 (rank : 290)
Query Neighborhood Hits	120	Target Neighborhood Hits	249	Shared Neighborhood Hits	37
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HHIP_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.057492 (rank : 288)
Query Neighborhood Hits	120	Target Neighborhood Hits	219	Shared Neighborhood Hits	34
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

ITB1_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.053414 (rank : 319)
Query Neighborhood Hits	120	Target Neighborhood Hits	298	Shared Neighborhood Hits	51
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB1_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.051302 (rank : 335)
Query Neighborhood Hits	120	Target Neighborhood Hits	283	Shared Neighborhood Hits	49
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB2_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.052830 (rank : 325)
Query Neighborhood Hits	120	Target Neighborhood Hits	326	Shared Neighborhood Hits	49
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB4_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.057765 (rank : 285)
Query Neighborhood Hits	120	Target Neighborhood Hits	458	Shared Neighborhood Hits	54
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

ITB5_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.058869 (rank : 277)
Query Neighborhood Hits	120	Target Neighborhood Hits	310	Shared Neighborhood Hits	54
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB5_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.060107 (rank : 267)
Query Neighborhood Hits	120	Target Neighborhood Hits	329	Shared Neighborhood Hits	53
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB6_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.050633 (rank : 344)
Query Neighborhood Hits	120	Target Neighborhood Hits	318	Shared Neighborhood Hits	48
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB6_MOUSE
θ value	θ > 10 (rank : 204)	NC score	0.055014 (rank : 304)
Query Neighborhood Hits	120	Target Neighborhood Hits	341	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB7_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.055652 (rank : 297)
Query Neighborhood Hits	120	Target Neighborhood Hits	290	Shared Neighborhood Hits	50
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

ITB7_MOUSE
θ value	θ > 10 (rank : 206)	NC score	0.053324 (rank : 320)
Query Neighborhood Hits	120	Target Neighborhood Hits	277	Shared Neighborhood Hits	44
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

JAG1_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.093865 (rank : 115)
Query Neighborhood Hits	120	Target Neighborhood Hits	514	Shared Neighborhood Hits	60
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
θ value	θ > 10 (rank : 208)	NC score	0.092641 (rank : 118)
Query Neighborhood Hits	120	Target Neighborhood Hits	518	Shared Neighborhood Hits	59
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG2_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.094765 (rank : 111)
Query Neighborhood Hits	120	Target Neighborhood Hits	491	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG2_MOUSE
θ value	θ > 10 (rank : 210)	NC score	0.091356 (rank : 121)
Query Neighborhood Hits	120	Target Neighborhood Hits	504	Shared Neighborhood Hits	58
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

KR101_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.090559 (rank : 124)
Query Neighborhood Hits	120	Target Neighborhood Hits	261	Shared Neighborhood Hits	51
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR102_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.076934 (rank : 181)
Query Neighborhood Hits	120	Target Neighborhood Hits	264	Shared Neighborhood Hits	46
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR104_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.111128 (rank : 67)
Query Neighborhood Hits	120	Target Neighborhood Hits	313	Shared Neighborhood Hits	53
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR105_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.077718 (rank : 180)
Query Neighborhood Hits	120	Target Neighborhood Hits	271	Shared Neighborhood Hits	40
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR106_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.108990 (rank : 74)
Query Neighborhood Hits	120	Target Neighborhood Hits	347	Shared Neighborhood Hits	60
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR107_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.107246 (rank : 78)
Query Neighborhood Hits	120	Target Neighborhood Hits	330	Shared Neighborhood Hits	54
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR108_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.085745 (rank : 145)
Query Neighborhood Hits	120	Target Neighborhood Hits	226	Shared Neighborhood Hits	41
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR109_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.072576 (rank : 206)
Query Neighborhood Hits	120	Target Neighborhood Hits	226	Shared Neighborhood Hits	43
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR10A_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.050937 (rank : 340)
Query Neighborhood Hits	120	Target Neighborhood Hits	232	Shared Neighborhood Hits	42
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

KR10B_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.077829 (rank : 179)
Query Neighborhood Hits	120	Target Neighborhood Hits	269	Shared Neighborhood Hits	46
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KR10C_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.062739 (rank : 257)
Query Neighborhood Hits	120	Target Neighborhood Hits	219	Shared Neighborhood Hits	40
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KR171_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.068770 (rank : 221)
Query Neighborhood Hits	120	Target Neighborhood Hits	144	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KR410_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.060451 (rank : 265)
Query Neighborhood Hits	120	Target Neighborhood Hits	156	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

KR412_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.080394 (rank : 164)
Query Neighborhood Hits	120	Target Neighborhood Hits	178	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR414_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.074195 (rank : 196)
Query Neighborhood Hits	120	Target Neighborhood Hits	199	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KR510_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.093773 (rank : 116)
Query Neighborhood Hits	120	Target Neighborhood Hits	217	Shared Neighborhood Hits	36
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KR511_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.082018 (rank : 155)
Query Neighborhood Hits	120	Target Neighborhood Hits	231	Shared Neighborhood Hits	33
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA11_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.052627 (rank : 328)
Query Neighborhood Hits	120	Target Neighborhood Hits	155	Shared Neighborhood Hits	24
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

KRA13_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.067119 (rank : 230)
Query Neighborhood Hits	120	Target Neighborhood Hits	144	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

KRA15_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.055190 (rank : 301)
Query Neighborhood Hits	120	Target Neighborhood Hits	126	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KRA44_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.075827 (rank : 188)
Query Neighborhood Hits	120	Target Neighborhood Hits	162	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KRA45_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.084775 (rank : 148)
Query Neighborhood Hits	120	Target Neighborhood Hits	194	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

KRA47_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.088964 (rank : 127)
Query Neighborhood Hits	120	Target Neighborhood Hits	204	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KRA51_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.126117 (rank : 43)
Query Neighborhood Hits	120	Target Neighborhood Hits	288	Shared Neighborhood Hits	51
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA52_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.100065 (rank : 98)
Query Neighborhood Hits	120	Target Neighborhood Hits	236	Shared Neighborhood Hits	37
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KRA53_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.121291 (rank : 51)
Query Neighborhood Hits	120	Target Neighborhood Hits	331	Shared Neighborhood Hits	53
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA54_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.107087 (rank : 79)
Query Neighborhood Hits	120	Target Neighborhood Hits	270	Shared Neighborhood Hits	42
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA55_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.118827 (rank : 53)
Query Neighborhood Hits	120	Target Neighborhood Hits	257	Shared Neighborhood Hits	47
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA56_HUMAN
θ value	θ > 10 (rank : 239)	NC score	0.092211 (rank : 119)
Query Neighborhood Hits	120	Target Neighborhood Hits	207	Shared Neighborhood Hits	35
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA57_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.094364 (rank : 113)
Query Neighborhood Hits	120	Target Neighborhood Hits	269	Shared Neighborhood Hits	43
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA58_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.109375 (rank : 73)
Query Neighborhood Hits	120	Target Neighborhood Hits	324	Shared Neighborhood Hits	51
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA59_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.110384 (rank : 70)
Query Neighborhood Hits	120	Target Neighborhood Hits	310	Shared Neighborhood Hits	46
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KRA92_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.085094 (rank : 146)
Query Neighborhood Hits	120	Target Neighborhood Hits	198	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA93_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.093343 (rank : 117)
Query Neighborhood Hits	120	Target Neighborhood Hits	203	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA94_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.079852 (rank : 165)
Query Neighborhood Hits	120	Target Neighborhood Hits	204	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KRA98_HUMAN
θ value	θ > 10 (rank : 246)	NC score	0.088629 (rank : 131)
Query Neighborhood Hits	120	Target Neighborhood Hits	185	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA99_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.078576 (rank : 171)
Query Neighborhood Hits	120	Target Neighborhood Hits	173	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

LAMA1_MOUSE
θ value	θ > 10 (rank : 248)	NC score	0.075328 (rank : 190)
Query Neighborhood Hits	120	Target Neighborhood Hits	838	Shared Neighborhood Hits	73
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA2_MOUSE
θ value	θ > 10 (rank : 249)	NC score	0.072824 (rank : 204)
Query Neighborhood Hits	120	Target Neighborhood Hits	1198	Shared Neighborhood Hits	69
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA3_MOUSE
θ value	θ > 10 (rank : 250)	NC score	0.062408 (rank : 258)
Query Neighborhood Hits	120	Target Neighborhood Hits	859	Shared Neighborhood Hits	68
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LAMA4_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.050287 (rank : 347)
Query Neighborhood Hits	120	Target Neighborhood Hits	708	Shared Neighborhood Hits	52
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA4_MOUSE
θ value	θ > 10 (rank : 252)	NC score	0.052842 (rank : 324)
Query Neighborhood Hits	120	Target Neighborhood Hits	584	Shared Neighborhood Hits	51
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA5_MOUSE
θ value	θ > 10 (rank : 253)	NC score	0.081083 (rank : 160)
Query Neighborhood Hits	120	Target Neighborhood Hits	828	Shared Neighborhood Hits	72
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB1_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.060057 (rank : 268)
Query Neighborhood Hits	120	Target Neighborhood Hits	1018	Shared Neighborhood Hits	54
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB1_MOUSE
θ value	θ > 10 (rank : 255)	NC score	0.065070 (rank : 246)
Query Neighborhood Hits	120	Target Neighborhood Hits	919	Shared Neighborhood Hits	54
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB2_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.082295 (rank : 154)
Query Neighborhood Hits	120	Target Neighborhood Hits	692	Shared Neighborhood Hits	67
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB2_MOUSE
θ value	θ > 10 (rank : 257)	NC score	0.073913 (rank : 199)
Query Neighborhood Hits	120	Target Neighborhood Hits	722	Shared Neighborhood Hits	63
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMB3_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.054561 (rank : 310)
Query Neighborhood Hits	120	Target Neighborhood Hits	461	Shared Neighborhood Hits	42
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMB3_MOUSE
θ value	θ > 10 (rank : 259)	NC score	0.061324 (rank : 262)
Query Neighborhood Hits	120	Target Neighborhood Hits	444	Shared Neighborhood Hits	52
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LAMC1_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.068229 (rank : 225)
Query Neighborhood Hits	120	Target Neighborhood Hits	922	Shared Neighborhood Hits	64
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC1_MOUSE
θ value	θ > 10 (rank : 261)	NC score	0.067919 (rank : 226)
Query Neighborhood Hits	120	Target Neighborhood Hits	856	Shared Neighborhood Hits	63
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC2_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.059009 (rank : 275)
Query Neighborhood Hits	120	Target Neighborhood Hits	715	Shared Neighborhood Hits	56
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LAMC2_MOUSE
θ value	θ > 10 (rank : 263)	NC score	0.061650 (rank : 260)
Query Neighborhood Hits	120	Target Neighborhood Hits	614	Shared Neighborhood Hits	59
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LAMC3_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.076899 (rank : 182)
Query Neighborhood Hits	120	Target Neighborhood Hits	588	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC3_MOUSE
θ value	θ > 10 (rank : 265)	NC score	0.072971 (rank : 203)
Query Neighborhood Hits	120	Target Neighborhood Hits	624	Shared Neighborhood Hits	64
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LCE1A_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.072344 (rank : 207)
Query Neighborhood Hits	120	Target Neighborhood Hits	47	Shared Neighborhood Hits	11
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LCE1B_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.095484 (rank : 109)
Query Neighborhood Hits	120	Target Neighborhood Hits	58	Shared Neighborhood Hits	14
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.075148 (rank : 192)
Query Neighborhood Hits	120	Target Neighborhood Hits	65	Shared Neighborhood Hits	15
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1E_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.073365 (rank : 201)
Query Neighborhood Hits	120	Target Neighborhood Hits	53	Shared Neighborhood Hits	11
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LCE1F_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.079552 (rank : 167)
Query Neighborhood Hits	120	Target Neighborhood Hits	48	Shared Neighborhood Hits	11
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LCE2A_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.050558 (rank : 345)
Query Neighborhood Hits	120	Target Neighborhood Hits	50	Shared Neighborhood Hits	11
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

LDLR_MOUSE
θ value	θ > 10 (rank : 272)	NC score	0.060705 (rank : 264)
Query Neighborhood Hits	120	Target Neighborhood Hits	382	Shared Neighborhood Hits	53
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP1B_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.069662 (rank : 217)
Query Neighborhood Hits	120	Target Neighborhood Hits	602	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1B_MOUSE
θ value	θ > 10 (rank : 274)	NC score	0.065573 (rank : 244)
Query Neighborhood Hits	120	Target Neighborhood Hits	606	Shared Neighborhood Hits	62
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.069367 (rank : 219)
Query Neighborhood Hits	120	Target Neighborhood Hits	617	Shared Neighborhood Hits	69
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP2_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.071098 (rank : 211)
Query Neighborhood Hits	120	Target Neighborhood Hits	573	Shared Neighborhood Hits	65
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LRP4_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.055097 (rank : 303)
Query Neighborhood Hits	120	Target Neighborhood Hits	355	Shared Neighborhood Hits	53
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP4_MOUSE
θ value	θ > 10 (rank : 278)	NC score	0.054501 (rank : 311)
Query Neighborhood Hits	120	Target Neighborhood Hits	351	Shared Neighborhood Hits	54
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LRP8_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.056528 (rank : 292)
Query Neighborhood Hits	120	Target Neighborhood Hits	346	Shared Neighborhood Hits	50
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP8_MOUSE
θ value	θ > 10 (rank : 280)	NC score	0.060765 (rank : 263)
Query Neighborhood Hits	120	Target Neighborhood Hits	385	Shared Neighborhood Hits	54
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LTBP3_HUMAN
θ value	θ > 10 (rank : 281)	NC score	0.098650 (rank : 102)
Query Neighborhood Hits	120	Target Neighborhood Hits	502	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP3_MOUSE
θ value	θ > 10 (rank : 282)	NC score	0.100094 (rank : 97)
Query Neighborhood Hits	120	Target Neighborhood Hits	475	Shared Neighborhood Hits	58
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

MATN2_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.088743 (rank : 129)
Query Neighborhood Hits	120	Target Neighborhood Hits	365	Shared Neighborhood Hits	55
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

MATN2_MOUSE
θ value	θ > 10 (rank : 284)	NC score	0.086946 (rank : 140)
Query Neighborhood Hits	120	Target Neighborhood Hits	356	Shared Neighborhood Hits	54
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MATN3_HUMAN
θ value	θ > 10 (rank : 285)	NC score	0.064245 (rank : 251)
Query Neighborhood Hits	120	Target Neighborhood Hits	268	Shared Neighborhood Hits	43
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_MOUSE
θ value	θ > 10 (rank : 286)	NC score	0.062046 (rank : 259)
Query Neighborhood Hits	120	Target Neighborhood Hits	261	Shared Neighborhood Hits	44
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.060045 (rank : 269)
Query Neighborhood Hits	120	Target Neighborhood Hits	287	Shared Neighborhood Hits	46
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MATN4_MOUSE
θ value	θ > 10 (rank : 288)	NC score	0.057474 (rank : 289)
Query Neighborhood Hits	120	Target Neighborhood Hits	277	Shared Neighborhood Hits	42
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

MEGF8_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.101594 (rank : 92)
Query Neighborhood Hits	120	Target Neighborhood Hits	528	Shared Neighborhood Hits	64
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.100125 (rank : 96)
Query Neighborhood Hits	120	Target Neighborhood Hits	520	Shared Neighborhood Hits	64
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MT3_MOUSE
θ value	θ > 10 (rank : 291)	NC score	0.051874 (rank : 332)
Query Neighborhood Hits	120	Target Neighborhood Hits	68	Shared Neighborhood Hits	17
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

MUC5B_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.064233 (rank : 252)
Query Neighborhood Hits	120	Target Neighborhood Hits	1020	Shared Neighborhood Hits	61
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NAGPA_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.071563 (rank : 210)
Query Neighborhood Hits	120	Target Neighborhood Hits	282	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NAGPA_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.064043 (rank : 254)
Query Neighborhood Hits	120	Target Neighborhood Hits	308	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NEC1_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.109719 (rank : 71)
Query Neighborhood Hits	120	Target Neighborhood Hits	20	Shared Neighborhood Hits	5
SwissProt Accessions	P29120, P78478, Q92532	Gene names	PCSK1, NEC1
Domain Architecture
Description	Neuroendocrine convertase 1 precursor (EC 3.4.21.93) (NEC 1) (PC1) (Prohormone convertase 1) (Proprotein convertase 1).

NEC1_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.109572 (rank : 72)
Query Neighborhood Hits	120	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	P63239, P21662, P22546	Gene names	Pcsk1, Att-1, Nec-1, Nec1
Domain Architecture	No domain graphic available
Description	Neuroendocrine convertase 1 precursor (EC 3.4.21.93) (NEC 1) (PC1) (Prohormone convertase 1) (Proprotein convertase 1) (PC3) (Furin homolog) (Propeptide-processing protease).

NEC2_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.107726 (rank : 77)
Query Neighborhood Hits	120	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	P16519, Q14927, Q9NQG3, Q9NUG1, Q9UJC6	Gene names	PCSK2, NEC2
Domain Architecture
Description	Neuroendocrine convertase 2 precursor (EC 3.4.21.94) (NEC 2) (PC2) (Prohormone convertase 2) (Proprotein convertase 2) (KEX2-like endoprotease 2).

NEC2_MOUSE
θ value	θ > 10 (rank : 298)	NC score	0.107911 (rank : 76)
Query Neighborhood Hits	120	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	P21661, Q80WU1	Gene names	Pcsk2, Nec-2, Nec2
Domain Architecture
Description	Neuroendocrine convertase 2 precursor (EC 3.4.21.94) (NEC 2) (PC2) (Prohormone convertase 2) (Proprotein convertase 2) (KEX2-like endoprotease 2).

NELL2_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.111484 (rank : 66)
Query Neighborhood Hits	120	Target Neighborhood Hits	449	Shared Neighborhood Hits	61
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
θ value	θ > 10 (rank : 300)	NC score	0.111620 (rank : 65)
Query Neighborhood Hits	120	Target Neighborhood Hits	436	Shared Neighborhood Hits	61
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NFX1_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.066039 (rank : 242)
Query Neighborhood Hits	120	Target Neighborhood Hits	405	Shared Neighborhood Hits	40
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

NID1_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.065915 (rank : 243)
Query Neighborhood Hits	120	Target Neighborhood Hits	329	Shared Neighborhood Hits	46
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_MOUSE
θ value	θ > 10 (rank : 303)	NC score	0.067293 (rank : 229)
Query Neighborhood Hits	120	Target Neighborhood Hits	335	Shared Neighborhood Hits	46
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.078203 (rank : 176)
Query Neighborhood Hits	120	Target Neighborhood Hits	456	Shared Neighborhood Hits	57
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID2_MOUSE
θ value	θ > 10 (rank : 305)	NC score	0.068263 (rank : 224)
Query Neighborhood Hits	120	Target Neighborhood Hits	338	Shared Neighborhood Hits	51
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NOTC2_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.094135 (rank : 114)
Query Neighborhood Hits	120	Target Neighborhood Hits	1069	Shared Neighborhood Hits	60
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC3_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.098797 (rank : 101)
Query Neighborhood Hits	120	Target Neighborhood Hits	1062	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
θ value	θ > 10 (rank : 308)	NC score	0.096883 (rank : 108)
Query Neighborhood Hits	120	Target Neighborhood Hits	975	Shared Neighborhood Hits	70
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC4_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.091150 (rank : 122)
Query Neighborhood Hits	120	Target Neighborhood Hits	872	Shared Neighborhood Hits	69
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

NTNG2_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.050220 (rank : 348)
Query Neighborhood Hits	120	Target Neighborhood Hits	276	Shared Neighborhood Hits	47
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

PCSK4_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.122770 (rank : 48)
Query Neighborhood Hits	120	Target Neighborhood Hits	32	Shared Neighborhood Hits	14
SwissProt Accessions	Q6UW60, Q8IY88, Q9UF79	Gene names	PCSK4, PC4
Domain Architecture	No domain graphic available
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (Proprotein convertase PC4).

PCSK4_MOUSE
θ value	θ > 10 (rank : 312)	NC score	0.112114 (rank : 64)
Query Neighborhood Hits	120	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	P29121, Q62094	Gene names	Pcsk4, Nec-3, Nec3
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (PC4) (Neuroendocrine convertase 3) (NEC 3) (Prohormone convertase 3) (KEX2-like endoprotease 3).

PCSK7_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.106955 (rank : 80)
Query Neighborhood Hits	120	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	Q16549, Q9UL57	Gene names	PCSK7, LPC, PC7, PC8, SPC7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (PC8) (hPC8) (Lymphoma proprotein convertase).

PCSK7_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.106899 (rank : 81)
Query Neighborhood Hits	120	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q61139, O08577	Gene names	Pcsk7, Pc7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (Subtilisin-like proprotein convertase 7) (SPC7).

PGBM_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.054895 (rank : 307)
Query Neighborhood Hits	120	Target Neighborhood Hits	1073	Shared Neighborhood Hits	70
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PROS_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.070162 (rank : 215)
Query Neighborhood Hits	120	Target Neighborhood Hits	340	Shared Neighborhood Hits	48
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.070161 (rank : 216)
Query Neighborhood Hits	120	Target Neighborhood Hits	330	Shared Neighborhood Hits	48
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

SCUB3_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.106243 (rank : 82)
Query Neighborhood Hits	120	Target Neighborhood Hits	428	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SEM5A_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.064742 (rank : 247)
Query Neighborhood Hits	120	Target Neighborhood Hits	177	Shared Neighborhood Hits	35
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEM5A_MOUSE
θ value	θ > 10 (rank : 320)	NC score	0.066685 (rank : 234)
Query Neighborhood Hits	120	Target Neighborhood Hits	162	Shared Neighborhood Hits	33
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEM5B_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.066083 (rank : 241)
Query Neighborhood Hits	120	Target Neighborhood Hits	178	Shared Neighborhood Hits	37
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

SEM5B_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.067376 (rank : 228)
Query Neighborhood Hits	120	Target Neighborhood Hits	190	Shared Neighborhood Hits	38
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

SORL_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.054179 (rank : 315)
Query Neighborhood Hits	120	Target Neighborhood Hits	440	Shared Neighborhood Hits	56
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SORL_MOUSE
θ value	θ > 10 (rank : 324)	NC score	0.057628 (rank : 286)
Query Neighborhood Hits	120	Target Neighborhood Hits	439	Shared Neighborhood Hits	63
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

STAB1_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.087539 (rank : 135)
Query Neighborhood Hits	120	Target Neighborhood Hits	546	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB1_MOUSE
θ value	θ > 10 (rank : 326)	NC score	0.087040 (rank : 139)
Query Neighborhood Hits	120	Target Neighborhood Hits	566	Shared Neighborhood Hits	63
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

STAB2_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.087231 (rank : 138)
Query Neighborhood Hits	120	Target Neighborhood Hits	534	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

STAB2_MOUSE
θ value	θ > 10 (rank : 328)	NC score	0.086758 (rank : 143)
Query Neighborhood Hits	120	Target Neighborhood Hits	528	Shared Neighborhood Hits	69
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

SUSD1_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.066167 (rank : 240)
Query Neighborhood Hits	120	Target Neighborhood Hits	285	Shared Neighborhood Hits	40
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TDGF1_MOUSE
θ value	θ > 10 (rank : 330)	NC score	0.051334 (rank : 334)
Query Neighborhood Hits	120	Target Neighborhood Hits	146	Shared Neighborhood Hits	31
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

TECTA_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.052596 (rank : 329)
Query Neighborhood Hits	120	Target Neighborhood Hits	244	Shared Neighborhood Hits	46
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TENA_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.076332 (rank : 184)
Query Neighborhood Hits	120	Target Neighborhood Hits	631	Shared Neighborhood Hits	64
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENA_MOUSE
θ value	θ > 10 (rank : 333)	NC score	0.072791 (rank : 205)
Query Neighborhood Hits	120	Target Neighborhood Hits	596	Shared Neighborhood Hits	59
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TENX_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.083981 (rank : 149)
Query Neighborhood Hits	120	Target Neighborhood Hits	789	Shared Neighborhood Hits	74
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

THSD1_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.056062 (rank : 296)
Query Neighborhood Hits	120	Target Neighborhood Hits	136	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

THSD1_MOUSE
θ value	θ > 10 (rank : 336)	NC score	0.058214 (rank : 282)
Query Neighborhood Hits	120	Target Neighborhood Hits	153	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

TIE1_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.058517 (rank : 279)
Query Neighborhood Hits	120	Target Neighborhood Hits	1241	Shared Neighborhood Hits	67
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE1_MOUSE
θ value	θ > 10 (rank : 338)	NC score	0.055215 (rank : 300)
Query Neighborhood Hits	120	Target Neighborhood Hits	1266	Shared Neighborhood Hits	62
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE2_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.051188 (rank : 337)
Query Neighborhood Hits	120	Target Neighborhood Hits	1192	Shared Neighborhood Hits	61
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TNR14_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.073952 (rank : 198)
Query Neighborhood Hits	120	Target Neighborhood Hits	149	Shared Neighborhood Hits	37
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TNR16_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.059721 (rank : 270)
Query Neighborhood Hits	120	Target Neighborhood Hits	183	Shared Neighborhood Hits	35
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR16_MOUSE
θ value	θ > 10 (rank : 342)	NC score	0.054090 (rank : 316)
Query Neighborhood Hits	120	Target Neighborhood Hits	178	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR25_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.059137 (rank : 273)
Query Neighborhood Hits	120	Target Neighborhood Hits	172	Shared Neighborhood Hits	35
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TNR26_MOUSE
θ value	θ > 10 (rank : 344)	NC score	0.055396 (rank : 299)
Query Neighborhood Hits	120	Target Neighborhood Hits	106	Shared Neighborhood Hits	27
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR5_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.051250 (rank : 336)
Query Neighborhood Hits	120	Target Neighborhood Hits	102	Shared Neighborhood Hits	22
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TNR9_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.054931 (rank : 305)
Query Neighborhood Hits	120	Target Neighborhood Hits	166	Shared Neighborhood Hits	33
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TNR9_MOUSE
θ value	θ > 10 (rank : 347)	NC score	0.053088 (rank : 321)
Query Neighborhood Hits	120	Target Neighborhood Hits	137	Shared Neighborhood Hits	21
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TRBM_HUMAN
θ value	θ > 10 (rank : 348)	NC score	0.088710 (rank : 130)
Query Neighborhood Hits	120	Target Neighborhood Hits	339	Shared Neighborhood Hits	55
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRBM_MOUSE
θ value	θ > 10 (rank : 349)	NC score	0.087504 (rank : 136)
Query Neighborhood Hits	120	Target Neighborhood Hits	361	Shared Neighborhood Hits	57
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TSP3_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.074289 (rank : 195)
Query Neighborhood Hits	120	Target Neighborhood Hits	250	Shared Neighborhood Hits	47
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_MOUSE
θ value	θ > 10 (rank : 351)	NC score	0.075075 (rank : 193)
Query Neighborhood Hits	120	Target Neighborhood Hits	247	Shared Neighborhood Hits	48
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP4_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.075728 (rank : 189)
Query Neighborhood Hits	120	Target Neighborhood Hits	277	Shared Neighborhood Hits	47
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_MOUSE
θ value	θ > 10 (rank : 353)	NC score	0.078402 (rank : 172)
Query Neighborhood Hits	120	Target Neighborhood Hits	276	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

UNC5A_MOUSE
θ value	θ > 10 (rank : 354)	NC score	0.060316 (rank : 266)
Query Neighborhood Hits	120	Target Neighborhood Hits	203	Shared Neighborhood Hits	27
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5B_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.064528 (rank : 248)
Query Neighborhood Hits	120	Target Neighborhood Hits	225	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5B_MOUSE
θ value	θ > 10 (rank : 356)	NC score	0.064467 (rank : 249)
Query Neighborhood Hits	120	Target Neighborhood Hits	226	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5C_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.057789 (rank : 284)
Query Neighborhood Hits	120	Target Neighborhood Hits	226	Shared Neighborhood Hits	26
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5C_MOUSE
θ value	θ > 10 (rank : 358)	NC score	0.057615 (rank : 287)
Query Neighborhood Hits	120	Target Neighborhood Hits	225	Shared Neighborhood Hits	26
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

UNC5D_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.054816 (rank : 308)
Query Neighborhood Hits	120	Target Neighborhood Hits	267	Shared Neighborhood Hits	28
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5D_MOUSE
θ value	θ > 10 (rank : 360)	NC score	0.054600 (rank : 309)
Query Neighborhood Hits	120	Target Neighborhood Hits	268	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UROM_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.078818 (rank : 169)
Query Neighborhood Hits	120	Target Neighborhood Hits	284	Shared Neighborhood Hits	47
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.078245 (rank : 173)
Query Neighborhood Hits	120	Target Neighborhood Hits	276	Shared Neighborhood Hits	50
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

USH2A_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.071090 (rank : 212)
Query Neighborhood Hits	120	Target Neighborhood Hits	600	Shared Neighborhood Hits	58
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

USH2A_MOUSE
θ value	θ > 10 (rank : 364)	NC score	0.078043 (rank : 178)
Query Neighborhood Hits	120	Target Neighborhood Hits	626	Shared Neighborhood Hits	62
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

VLDLR_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.058955 (rank : 276)
Query Neighborhood Hits	120	Target Neighborhood Hits	383	Shared Neighborhood Hits	48
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
θ value	θ > 10 (rank : 366)	NC score	0.058381 (rank : 281)
Query Neighborhood Hits	120	Target Neighborhood Hits	360	Shared Neighborhood Hits	47
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VWF_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.086839 (rank : 142)
Query Neighborhood Hits	120	Target Neighborhood Hits	396	Shared Neighborhood Hits	68
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

WISP2_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.051952 (rank : 331)
Query Neighborhood Hits	120	Target Neighborhood Hits	126	Shared Neighborhood Hits	36
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

ZAN_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.050034 (rank : 349)
Query Neighborhood Hits	120	Target Neighborhood Hits	679	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ZAN_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.123580 (rank : 47)
Query Neighborhood Hits	120	Target Neighborhood Hits	808	Shared Neighborhood Hits	79
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

ZNFX1_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.056130 (rank : 295)
Query Neighborhood Hits	120	Target Neighborhood Hits	308	Shared Neighborhood Hits	32
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ZNFX1_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.051560 (rank : 333)
Query Neighborhood Hits	120	Target Neighborhood Hits	407	Shared Neighborhood Hits	34
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

Hits sorted by NC score

RSPO3_MOUSE
NC score	0.999962 (rank : 1)	θ value	3.77839e-115 (rank : 1)
Query Neighborhood Hits	120	Target Neighborhood Hits	120	Shared Neighborhood Hits	120
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

RSPO3_HUMAN
NC score	0.991331 (rank : 2)	θ value	8.71062e-112 (rank : 2)
Query Neighborhood Hits	120	Target Neighborhood Hits	128	Shared Neighborhood Hits	100
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

RSPO1_HUMAN
NC score	0.953322 (rank : 3)	θ value	3.71096e-62 (rank : 3)
Query Neighborhood Hits	120	Target Neighborhood Hits	101	Shared Neighborhood Hits	67
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

RSPO1_MOUSE
NC score	0.952255 (rank : 4)	θ value	1.19377e-60 (rank : 4)
Query Neighborhood Hits	120	Target Neighborhood Hits	85	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

RSPO2_HUMAN
NC score	0.947329 (rank : 5)	θ value	1.66964e-54 (rank : 5)
Query Neighborhood Hits	120	Target Neighborhood Hits	90	Shared Neighborhood Hits	64
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

RSPO2_MOUSE
NC score	0.944932 (rank : 6)	θ value	4.85792e-54 (rank : 6)
Query Neighborhood Hits	120	Target Neighborhood Hits	88	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

RSPO4_HUMAN
NC score	0.918656 (rank : 7)	θ value	3.61106e-41 (rank : 7)
Query Neighborhood Hits	120	Target Neighborhood Hits	110	Shared Neighborhood Hits	60
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

RSPO4_MOUSE
NC score	0.914397 (rank : 8)	θ value	6.81017e-40 (rank : 8)
Query Neighborhood Hits	120	Target Neighborhood Hits	110	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

PCSK5_MOUSE
NC score	0.340799 (rank : 9)	θ value	3.29651e-10 (rank : 9)
Query Neighborhood Hits	120	Target Neighborhood Hits	613	Shared Neighborhood Hits	89
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

PCSK6_HUMAN
NC score	0.340776 (rank : 10)	θ value	4.30538e-10 (rank : 10)
Query Neighborhood Hits	120	Target Neighborhood Hits	298	Shared Neighborhood Hits	64
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

PCSK5_HUMAN
NC score	0.333171 (rank : 11)	θ value	5.26297e-08 (rank : 11)
Query Neighborhood Hits	120	Target Neighborhood Hits	291	Shared Neighborhood Hits	78
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

SPON2_HUMAN
NC score	0.300072 (rank : 12)	θ value	0.00390308 (rank : 22)
Query Neighborhood Hits	120	Target Neighborhood Hits	53	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BUD6, Q9ULW1	Gene names	SPON2, DIL1
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin) (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1).

FRAS1_MOUSE
NC score	0.291327 (rank : 13)	θ value	7.59969e-07 (rank : 13)
Query Neighborhood Hits	120	Target Neighborhood Hits	747	Shared Neighborhood Hits	91
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

SPON2_MOUSE
NC score	0.291184 (rank : 14)	θ value	0.0148317 (rank : 26)
Query Neighborhood Hits	120	Target Neighborhood Hits	42	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).

FRAS1_HUMAN
NC score	0.290835 (rank : 15)	θ value	8.97725e-08 (rank : 12)
Query Neighborhood Hits	120	Target Neighborhood Hits	759	Shared Neighborhood Hits	91
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

SPON1_MOUSE
NC score	0.281926 (rank : 16)	θ value	6.43352e-06 (rank : 14)
Query Neighborhood Hits	120	Target Neighborhood Hits	123	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

SPON1_HUMAN
NC score	0.280858 (rank : 17)	θ value	2.44474e-05 (rank : 16)
Query Neighborhood Hits	120	Target Neighborhood Hits	117	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

PROP_MOUSE
NC score	0.182787 (rank : 18)	θ value	0.365318 (rank : 49)
Query Neighborhood Hits	120	Target Neighborhood Hits	165	Shared Neighborhood Hits	42
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

SSPO_MOUSE
NC score	0.179572 (rank : 19)	θ value	0.0961366 (rank : 36)
Query Neighborhood Hits	120	Target Neighborhood Hits	800	Shared Neighborhood Hits	93
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

FURIN_HUMAN
NC score	0.178969 (rank : 20)	θ value	0.365318 (rank : 48)
Query Neighborhood Hits	120	Target Neighborhood Hits	52	Shared Neighborhood Hits	24
SwissProt Accessions	P09958, Q14336, Q6LBS3	Gene names	FURIN, FUR, PACE
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme).

FURIN_MOUSE
NC score	0.175785 (rank : 21)	θ value	0.279714 (rank : 44)
Query Neighborhood Hits	120	Target Neighborhood Hits	49	Shared Neighborhood Hits	25
SwissProt Accessions	P23188	Gene names	Furin, Fur, Pcsk3
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme) (Prohormone convertase 3).

CREL1_MOUSE
NC score	0.172853 (rank : 22)	θ value	0.125558 (rank : 37)
Query Neighborhood Hits	120	Target Neighborhood Hits	524	Shared Neighborhood Hits	64
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

PROP_HUMAN
NC score	0.170666 (rank : 23)	θ value	0.47712 (rank : 53)
Query Neighborhood Hits	120	Target Neighborhood Hits	126	Shared Neighborhood Hits	43
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

CREL1_HUMAN
NC score	0.170036 (rank : 24)	θ value	0.0431538 (rank : 29)
Query Neighborhood Hits	120	Target Neighborhood Hits	441	Shared Neighborhood Hits	60
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

MEGF6_HUMAN
NC score	0.145695 (rank : 25)	θ value	0.279714 (rank : 45)
Query Neighborhood Hits	120	Target Neighborhood Hits	671	Shared Neighborhood Hits	86
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

TSP1_MOUSE
NC score	0.144534 (rank : 26)	θ value	0.813845 (rank : 62)
Query Neighborhood Hits	120	Target Neighborhood Hits	396	Shared Neighborhood Hits	76
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

TNR6B_HUMAN
NC score	0.144336 (rank : 27)	θ value	0.00509761 (rank : 23)
Query Neighborhood Hits	120	Target Neighborhood Hits	103	Shared Neighborhood Hits	24
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TSP1_HUMAN
NC score	0.144063 (rank : 28)	θ value	0.365318 (rank : 50)
Query Neighborhood Hits	120	Target Neighborhood Hits	389	Shared Neighborhood Hits	76
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

SREC2_MOUSE
NC score	0.143947 (rank : 29)	θ value	0.0431538 (rank : 30)
Query Neighborhood Hits	120	Target Neighborhood Hits	605	Shared Neighborhood Hits	72
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SREC2_HUMAN
NC score	0.143110 (rank : 30)	θ value	0.47712 (rank : 54)
Query Neighborhood Hits	120	Target Neighborhood Hits	645	Shared Neighborhood Hits	70
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

BAI2_HUMAN
NC score	0.142287 (rank : 31)	θ value	0.0252991 (rank : 27)
Query Neighborhood Hits	120	Target Neighborhood Hits	332	Shared Neighborhood Hits	41
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_MOUSE
NC score	0.141472 (rank : 32)	θ value	0.0252991 (rank : 28)
Query Neighborhood Hits	120	Target Neighborhood Hits	323	Shared Neighborhood Hits	42
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

SREC_HUMAN
NC score	0.140655 (rank : 33)	θ value	1.38821 (rank : 70)
Query Neighborhood Hits	120	Target Neighborhood Hits	645	Shared Neighborhood Hits	76
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

TSP2_HUMAN
NC score	0.137619 (rank : 34)	θ value	1.81305 (rank : 77)
Query Neighborhood Hits	120	Target Neighborhood Hits	359	Shared Neighborhood Hits	74
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP2_MOUSE
NC score	0.136442 (rank : 35)	θ value	0.365318 (rank : 51)
Query Neighborhood Hits	120	Target Neighborhood Hits	352	Shared Neighborhood Hits	71
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

LTBP4_MOUSE
NC score	0.132569 (rank : 36)	θ value	0.813845 (rank : 61)
Query Neighborhood Hits	120	Target Neighborhood Hits	607	Shared Neighborhood Hits	70
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

FBN1_HUMAN
NC score	0.131710 (rank : 37)	θ value	0.163984 (rank : 39)
Query Neighborhood Hits	120	Target Neighborhood Hits	557	Shared Neighborhood Hits	76
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_MOUSE
NC score	0.130470 (rank : 38)	θ value	0.163984 (rank : 40)
Query Neighborhood Hits	120	Target Neighborhood Hits	563	Shared Neighborhood Hits	71
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

BAI1_HUMAN
NC score	0.130415 (rank : 39)	θ value	0.0961366 (rank : 34)
Query Neighborhood Hits	120	Target Neighborhood Hits	375	Shared Neighborhood Hits	42
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

LTBP2_MOUSE
NC score	0.129302 (rank : 40)	θ value	0.0563607 (rank : 31)
Query Neighborhood Hits	120	Target Neighborhood Hits	617	Shared Neighborhood Hits	68
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

NELL1_HUMAN
NC score	0.126822 (rank : 41)	θ value	0.0736092 (rank : 32)
Query Neighborhood Hits	120	Target Neighborhood Hits	451	Shared Neighborhood Hits	65
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

BAI3_HUMAN
NC score	0.126510 (rank : 42)	θ value	1.81305 (rank : 72)
Query Neighborhood Hits	120	Target Neighborhood Hits	246	Shared Neighborhood Hits	43
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

KRA51_HUMAN
NC score	0.126117 (rank : 43)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	120	Target Neighborhood Hits	288	Shared Neighborhood Hits	51
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

BAI3_MOUSE
NC score	0.126043 (rank : 44)	θ value	1.81305 (rank : 73)
Query Neighborhood Hits	120	Target Neighborhood Hits	250	Shared Neighborhood Hits	41
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

CRIM1_HUMAN
NC score	0.125272 (rank : 45)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	120	Target Neighborhood Hits	362	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

BAI1_MOUSE
NC score	0.124244 (rank : 46)	θ value	0.0961366 (rank : 35)
Query Neighborhood Hits	120	Target Neighborhood Hits	340	Shared Neighborhood Hits	37
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

ZAN_MOUSE
NC score	0.123580 (rank : 47)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	120	Target Neighborhood Hits	808	Shared Neighborhood Hits	79
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

PCSK4_HUMAN
NC score	0.122770 (rank : 48)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	120	Target Neighborhood Hits	32	Shared Neighborhood Hits	14
SwissProt Accessions	Q6UW60, Q8IY88, Q9UF79	Gene names	PCSK4, PC4
Domain Architecture	No domain graphic available
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (Proprotein convertase PC4).

FBN2_HUMAN
NC score	0.122574 (rank : 49)	θ value	1.81305 (rank : 76)
Query Neighborhood Hits	120	Target Neighborhood Hits	560	Shared Neighborhood Hits	67
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
NC score	0.122273 (rank : 50)	θ value	1.06291 (rank : 66)
Query Neighborhood Hits	120	Target Neighborhood Hits	549	Shared Neighborhood Hits	69
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

KRA53_HUMAN
NC score	0.121291 (rank : 51)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	120	Target Neighborhood Hits	331	Shared Neighborhood Hits	53
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

FBN3_HUMAN
NC score	0.121145 (rank : 52)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	120	Target Neighborhood Hits	543	Shared Neighborhood Hits	62
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

KRA55_HUMAN
NC score	0.118827 (rank : 53)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	120	Target Neighborhood Hits	257	Shared Neighborhood Hits	47
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

HMCN1_HUMAN
NC score	0.118752 (rank : 54)	θ value	0.00665767 (rank : 24)
Query Neighborhood Hits	120	Target Neighborhood Hits	983	Shared Neighborhood Hits	86
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

LTBP2_HUMAN
NC score	0.117541 (rank : 55)	θ value	3.0926 (rank : 88)
Query Neighborhood Hits	120	Target Neighborhood Hits	552	Shared Neighborhood Hits	69
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

BMPER_HUMAN
NC score	0.117388 (rank : 56)	θ value	0.365318 (rank : 47)
Query Neighborhood Hits	120	Target Neighborhood Hits	175	Shared Neighborhood Hits	42
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

LTB1S_MOUSE
NC score	0.116470 (rank : 57)	θ value	1.06291 (rank : 68)
Query Neighborhood Hits	120	Target Neighborhood Hits	479	Shared Neighborhood Hits	66
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

WIF1_MOUSE
NC score	0.114889 (rank : 58)	θ value	0.813845 (rank : 64)
Query Neighborhood Hits	120	Target Neighborhood Hits	393	Shared Neighborhood Hits	59
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

SCUB3_MOUSE
NC score	0.113543 (rank : 59)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	120	Target Neighborhood Hits	442	Shared Neighborhood Hits	65
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

WIF1_HUMAN
NC score	0.113343 (rank : 60)	θ value	0.813845 (rank : 63)
Query Neighborhood Hits	120	Target Neighborhood Hits	392	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

NOTC1_MOUSE
NC score	0.112835 (rank : 61)	θ value	0.125558 (rank : 38)
Query Neighborhood Hits	120	Target Neighborhood Hits	916	Shared Neighborhood Hits	69
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

LTB1L_MOUSE
NC score	0.112683 (rank : 62)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	120	Target Neighborhood Hits	514	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

NOTC1_HUMAN
NC score	0.112553 (rank : 63)	θ value	0.0736092 (rank : 33)
Query Neighborhood Hits	120	Target Neighborhood Hits	906	Shared Neighborhood Hits	72
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

PCSK4_MOUSE
NC score	0.112114 (rank : 64)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	120	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	P29121, Q62094	Gene names	Pcsk4, Nec-3, Nec3
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (PC4) (Neuroendocrine convertase 3) (NEC 3) (Prohormone convertase 3) (KEX2-like endoprotease 3).

NELL2_MOUSE
NC score	0.111620 (rank : 65)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	120	Target Neighborhood Hits	436	Shared Neighborhood Hits	61
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NELL2_HUMAN
NC score	0.111484 (rank : 66)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	120	Target Neighborhood Hits	449	Shared Neighborhood Hits	61
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

KR104_HUMAN
NC score	0.111128 (rank : 67)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	120	Target Neighborhood Hits	313	Shared Neighborhood Hits	53
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

LTB1S_HUMAN
NC score	0.110684 (rank : 68)	θ value	2.36792 (rank : 82)
Query Neighborhood Hits	120	Target Neighborhood Hits	502	Shared Neighborhood Hits	63
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_HUMAN
NC score	0.110427 (rank : 69)	θ value	2.36792 (rank : 81)
Query Neighborhood Hits	120	Target Neighborhood Hits	553	Shared Neighborhood Hits	64
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

KRA59_HUMAN
NC score	0.110384 (rank : 70)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	120	Target Neighborhood Hits	310	Shared Neighborhood Hits	46
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

NEC1_HUMAN
NC score	0.109719 (rank : 71)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	120	Target Neighborhood Hits	20	Shared Neighborhood Hits	5
SwissProt Accessions	P29120, P78478, Q92532	Gene names	PCSK1, NEC1
Domain Architecture
Description	Neuroendocrine convertase 1 precursor (EC 3.4.21.93) (NEC 1) (PC1) (Prohormone convertase 1) (Proprotein convertase 1).

NEC1_MOUSE
NC score	0.109572 (rank : 72)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	120	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	P63239, P21662, P22546	Gene names	Pcsk1, Att-1, Nec-1, Nec1
Domain Architecture	No domain graphic available
Description	Neuroendocrine convertase 1 precursor (EC 3.4.21.93) (NEC 1) (PC1) (Prohormone convertase 1) (Proprotein convertase 1) (PC3) (Furin homolog) (Propeptide-processing protease).

KRA58_HUMAN
NC score	0.109375 (rank : 73)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	120	Target Neighborhood Hits	324	Shared Neighborhood Hits	51
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KR106_HUMAN
NC score	0.108990 (rank : 74)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	120	Target Neighborhood Hits	347	Shared Neighborhood Hits	60
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

INSRR_HUMAN
NC score	0.108943 (rank : 75)	θ value	1.87187e-05 (rank : 15)
Query Neighborhood Hits	120	Target Neighborhood Hits	950	Shared Neighborhood Hits	59
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

NEC2_MOUSE
NC score	0.107911 (rank : 76)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	120	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	P21661, Q80WU1	Gene names	Pcsk2, Nec-2, Nec2
Domain Architecture
Description	Neuroendocrine convertase 2 precursor (EC 3.4.21.94) (NEC 2) (PC2) (Prohormone convertase 2) (Proprotein convertase 2) (KEX2-like endoprotease 2).

NEC2_HUMAN
NC score	0.107726 (rank : 77)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	120	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	P16519, Q14927, Q9NQG3, Q9NUG1, Q9UJC6	Gene names	PCSK2, NEC2
Domain Architecture
Description	Neuroendocrine convertase 2 precursor (EC 3.4.21.94) (NEC 2) (PC2) (Prohormone convertase 2) (Proprotein convertase 2) (KEX2-like endoprotease 2).

KR107_HUMAN
NC score	0.107246 (rank : 78)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	120	Target Neighborhood Hits	330	Shared Neighborhood Hits	54
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KRA54_HUMAN
NC score	0.107087 (rank : 79)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	120	Target Neighborhood Hits	270	Shared Neighborhood Hits	42
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

PCSK7_HUMAN
NC score	0.106955 (rank : 80)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	120	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	Q16549, Q9UL57	Gene names	PCSK7, LPC, PC7, PC8, SPC7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (PC8) (hPC8) (Lymphoma proprotein convertase).

PCSK7_MOUSE
NC score	0.106899 (rank : 81)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	120	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q61139, O08577	Gene names	Pcsk7, Pc7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (Subtilisin-like proprotein convertase 7) (SPC7).

SCUB3_HUMAN
NC score	0.106243 (rank : 82)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	120	Target Neighborhood Hits	428	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

INSRR_MOUSE
NC score	0.106214 (rank : 83)	θ value	5.44631e-05 (rank : 17)
Query Neighborhood Hits	120	Target Neighborhood Hits	961	Shared Neighborhood Hits	60
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

IGF1R_MOUSE
NC score	0.106177 (rank : 84)	θ value	9.29e-05 (rank : 18)
Query Neighborhood Hits	120	Target Neighborhood Hits	973	Shared Neighborhood Hits	59
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

FBLN5_MOUSE
NC score	0.105148 (rank : 85)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	120	Target Neighborhood Hits	317	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

NOTC2_HUMAN
NC score	0.104761 (rank : 86)	θ value	0.00869519 (rank : 25)
Query Neighborhood Hits	120	Target Neighborhood Hits	1113	Shared Neighborhood Hits	70
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

IGF1R_HUMAN
NC score	0.103690 (rank : 87)	θ value	0.00035302 (rank : 19)
Query Neighborhood Hits	120	Target Neighborhood Hits	977	Shared Neighborhood Hits	53
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

FBLN1_HUMAN
NC score	0.103293 (rank : 88)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	120	Target Neighborhood Hits	324	Shared Neighborhood Hits	53
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

MEGF9_HUMAN
NC score	0.103122 (rank : 89)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	120	Target Neighborhood Hits	557	Shared Neighborhood Hits	66
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

FBLN5_HUMAN
NC score	0.102006 (rank : 90)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	120	Target Neighborhood Hits	329	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

MEGF9_MOUSE
NC score	0.101927 (rank : 91)	θ value	6.88961 (rank : 107)
Query Neighborhood Hits	120	Target Neighborhood Hits	896	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEGF8_HUMAN
NC score	0.101594 (rank : 92)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	120	Target Neighborhood Hits	528	Shared Neighborhood Hits	64
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

FBLN1_MOUSE
NC score	0.101576 (rank : 93)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	120	Target Neighborhood Hits	329	Shared Neighborhood Hits	58
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

TNR5_MOUSE
NC score	0.100350 (rank : 94)	θ value	1.38821 (rank : 71)
Query Neighborhood Hits	120	Target Neighborhood Hits	131	Shared Neighborhood Hits	31
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

C1QR1_HUMAN
NC score	0.100252 (rank : 95)	θ value	3.0926 (rank : 84)
Query Neighborhood Hits	120	Target Neighborhood Hits	493	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

MEGF8_MOUSE
NC score	0.100125 (rank : 96)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	120	Target Neighborhood Hits	520	Shared Neighborhood Hits	64
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

LTBP3_MOUSE
NC score	0.100094 (rank : 97)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	120	Target Neighborhood Hits	475	Shared Neighborhood Hits	58
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

KRA52_HUMAN
NC score	0.100065 (rank : 98)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	120	Target Neighborhood Hits	236	Shared Neighborhood Hits	37
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

INSR_MOUSE
NC score	0.099665 (rank : 99)	θ value	0.00102713 (rank : 21)
Query Neighborhood Hits	120	Target Neighborhood Hits	968	Shared Neighborhood Hits	48
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

FBLN2_MOUSE
NC score	0.099253 (rank : 100)	θ value	4.03905 (rank : 92)
Query Neighborhood Hits	120	Target Neighborhood Hits	505	Shared Neighborhood Hits	60
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

NOTC3_HUMAN
NC score	0.098797 (rank : 101)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	120	Target Neighborhood Hits	1062	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

LTBP3_HUMAN
NC score	0.098650 (rank : 102)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	120	Target Neighborhood Hits	502	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

FBLN2_HUMAN
NC score	0.098486 (rank : 103)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	120	Target Neighborhood Hits	392	Shared Neighborhood Hits	55
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

BMPER_MOUSE
NC score	0.098206 (rank : 104)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	120	Target Neighborhood Hits	194	Shared Neighborhood Hits	45
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

INSR_HUMAN
NC score	0.097863 (rank : 105)	θ value	0.000786445 (rank : 20)
Query Neighborhood Hits	120	Target Neighborhood Hits	963	Shared Neighborhood Hits	49
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

NOTC4_HUMAN
NC score	0.097662 (rank : 106)	θ value	1.38821 (rank : 69)
Query Neighborhood Hits	120	Target Neighborhood Hits	905	Shared Neighborhood Hits	72
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

DLL4_MOUSE
NC score	0.097630 (rank : 107)	θ value	0.813845 (rank : 58)
Query Neighborhood Hits	120	Target Neighborhood Hits	440	Shared Neighborhood Hits	59
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

NOTC3_MOUSE
NC score	0.096883 (rank : 108)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	120	Target Neighborhood Hits	975	Shared Neighborhood Hits	70
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

LCE1B_HUMAN
NC score	0.095484 (rank : 109)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	120	Target Neighborhood Hits	58	Shared Neighborhood Hits	14
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

DLL4_HUMAN
NC score	0.095005 (rank : 110)	θ value	0.47712 (rank : 52)
Query Neighborhood Hits	120	Target Neighborhood Hits	435	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

JAG2_HUMAN
NC score	0.094765 (rank : 111)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	120	Target Neighborhood Hits	491	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

FBLN3_HUMAN
NC score	0.094452 (rank : 112)	θ value	1.06291 (rank : 65)
Query Neighborhood Hits	120	Target Neighborhood Hits	293	Shared Neighborhood Hits	54
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

KRA57_HUMAN
NC score	0.094364 (rank : 113)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	120	Target Neighborhood Hits	269	Shared Neighborhood Hits	43
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

NOTC2_MOUSE
NC score	0.094135 (rank : 114)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	120	Target Neighborhood Hits	1069	Shared Neighborhood Hits	60
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

JAG1_HUMAN
NC score	0.093865 (rank : 115)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	120	Target Neighborhood Hits	514	Shared Neighborhood Hits	60
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

KR510_HUMAN
NC score	0.093773 (rank : 116)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	120	Target Neighborhood Hits	217	Shared Neighborhood Hits	36
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KRA93_HUMAN
NC score	0.093343 (rank : 117)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	120	Target Neighborhood Hits	203	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

JAG1_MOUSE
NC score	0.092641 (rank : 118)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	120	Target Neighborhood Hits	518	Shared Neighborhood Hits	59
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

KRA56_HUMAN
NC score	0.092211 (rank : 119)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	120	Target Neighborhood Hits	207	Shared Neighborhood Hits	35
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

FBLN4_MOUSE
NC score	0.092016 (rank : 120)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	120	Target Neighborhood Hits	270	Shared Neighborhood Hits	50
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

JAG2_MOUSE
NC score	0.091356 (rank : 121)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	120	Target Neighborhood Hits	504	Shared Neighborhood Hits	58
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

NOTC4_MOUSE
NC score	0.091150 (rank : 122)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	120	Target Neighborhood Hits	872	Shared Neighborhood Hits	69
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

LAMA5_HUMAN
NC score	0.090898 (rank : 123)	θ value	0.62314 (rank : 57)
Query Neighborhood Hits	120	Target Neighborhood Hits	976	Shared Neighborhood Hits	79
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

KR101_HUMAN
NC score	0.090559 (rank : 124)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	120	Target Neighborhood Hits	261	Shared Neighborhood Hits	51
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

DLL3_MOUSE
NC score	0.090270 (rank : 125)	θ value	1.81305 (rank : 75)
Query Neighborhood Hits	120	Target Neighborhood Hits	399	Shared Neighborhood Hits	55
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

C1QR1_MOUSE
NC score	0.089229 (rank : 126)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	120	Target Neighborhood Hits	342	Shared Neighborhood Hits	55
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

KRA47_HUMAN
NC score	0.088964 (rank : 127)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	120	Target Neighborhood Hits	204	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

CILP1_HUMAN
NC score	0.088908 (rank : 128)	θ value	1.81305 (rank : 74)
Query Neighborhood Hits	120	Target Neighborhood Hits	266	Shared Neighborhood Hits	37
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

MATN2_HUMAN
NC score	0.088743 (rank : 129)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	120	Target Neighborhood Hits	365	Shared Neighborhood Hits	55
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

TRBM_HUMAN
NC score	0.088710 (rank : 130)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	120	Target Neighborhood Hits	339	Shared Neighborhood Hits	55
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

KRA98_HUMAN
NC score	0.088629 (rank : 131)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	120	Target Neighborhood Hits	185	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

VWF_MOUSE
NC score	0.088318 (rank : 132)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	120	Target Neighborhood Hits	381	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

FBLN4_HUMAN
NC score	0.088084 (rank : 133)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	120	Target Neighborhood Hits	278	Shared Neighborhood Hits	48
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

DLL1_MOUSE
NC score	0.087686 (rank : 134)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	120	Target Neighborhood Hits	456	Shared Neighborhood Hits	61
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

STAB1_HUMAN
NC score	0.087539 (rank : 135)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	120	Target Neighborhood Hits	546	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

TRBM_MOUSE
NC score	0.087504 (rank : 136)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	120	Target Neighborhood Hits	361	Shared Neighborhood Hits	57
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

FBLN3_MOUSE
NC score	0.087281 (rank : 137)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	120	Target Neighborhood Hits	279	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

STAB2_HUMAN
NC score	0.087231 (rank : 138)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	120	Target Neighborhood Hits	534	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

STAB1_MOUSE
NC score	0.087040 (rank : 139)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	120	Target Neighborhood Hits	566	Shared Neighborhood Hits	63
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

MATN2_MOUSE
NC score	0.086946 (rank : 140)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	120	Target Neighborhood Hits	356	Shared Neighborhood Hits	54
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

DLL1_HUMAN
NC score	0.086922 (rank : 141)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	120	Target Neighborhood Hits	455	Shared Neighborhood Hits	58
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

VWF_HUMAN
NC score	0.086839 (rank : 142)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	120	Target Neighborhood Hits	396	Shared Neighborhood Hits	68
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

STAB2_MOUSE
NC score	0.086758 (rank : 143)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	120	Target Neighborhood Hits	528	Shared Neighborhood Hits	69
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

CILP2_HUMAN
NC score	0.086216 (rank : 144)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	120	Target Neighborhood Hits	307	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

KR108_HUMAN
NC score	0.085745 (rank : 145)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	120	Target Neighborhood Hits	226	Shared Neighborhood Hits	41
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KRA92_HUMAN
NC score	0.085094 (rank : 146)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	120	Target Neighborhood Hits	198	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

DLL3_HUMAN
NC score	0.084938 (rank : 147)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	120	Target Neighborhood Hits	419	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

KRA45_HUMAN
NC score	0.084775 (rank : 148)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	120	Target Neighborhood Hits	194	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

TENX_HUMAN
NC score	0.083981 (rank : 149)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	120	Target Neighborhood Hits	789	Shared Neighborhood Hits	74
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

CRUM1_MOUSE
NC score	0.083105 (rank : 150)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	120	Target Neighborhood Hits	444	Shared Neighborhood Hits	54
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

EGFL9_HUMAN
NC score	0.082884 (rank : 151)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	120	Target Neighborhood Hits	365	Shared Neighborhood Hits	56
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

CRUM2_HUMAN
NC score	0.082827 (rank : 152)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	120	Target Neighborhood Hits	453	Shared Neighborhood Hits	59
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

EMR1_HUMAN
NC score	0.082689 (rank : 153)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	120	Target Neighborhood Hits	382	Shared Neighborhood Hits	58
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

LAMB2_HUMAN
NC score	0.082295 (rank : 154)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	120	Target Neighborhood Hits	692	Shared Neighborhood Hits	67
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

KR511_HUMAN
NC score	0.082018 (rank : 155)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	120	Target Neighborhood Hits	231	Shared Neighborhood Hits	33
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

DNER_HUMAN
NC score	0.081898 (rank : 156)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	120	Target Neighborhood Hits	460	Shared Neighborhood Hits	54
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

ATS16_MOUSE
NC score	0.081507 (rank : 157)	θ value	0.279714 (rank : 43)
Query Neighborhood Hits	120	Target Neighborhood Hits	179	Shared Neighborhood Hits	38
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

EGFL9_MOUSE
NC score	0.081493 (rank : 158)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	120	Target Neighborhood Hits	379	Shared Neighborhood Hits	54
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

LAMA1_HUMAN
NC score	0.081243 (rank : 159)	θ value	6.88961 (rank : 106)
Query Neighborhood Hits	120	Target Neighborhood Hits	804	Shared Neighborhood Hits	70
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA5_MOUSE
NC score	0.081083 (rank : 160)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	120	Target Neighborhood Hits	828	Shared Neighborhood Hits	72
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

COMP_MOUSE
NC score	0.081007 (rank : 161)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	120	Target Neighborhood Hits	290	Shared Neighborhood Hits	49
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

COMP_HUMAN
NC score	0.080920 (rank : 162)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	120	Target Neighborhood Hits	258	Shared Neighborhood Hits	47
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CRUM1_HUMAN
NC score	0.080715 (rank : 163)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	120	Target Neighborhood Hits	457	Shared Neighborhood Hits	53
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

KR412_HUMAN
NC score	0.080394 (rank : 164)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	120	Target Neighborhood Hits	178	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KRA94_HUMAN
NC score	0.079852 (rank : 165)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	120	Target Neighborhood Hits	204	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

ATS20_MOUSE
NC score	0.079595 (rank : 166)	θ value	2.36792 (rank : 78)
Query Neighborhood Hits	120	Target Neighborhood Hits	225	Shared Neighborhood Hits	44
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

LCE1F_HUMAN
NC score	0.079552 (rank : 167)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	120	Target Neighborhood Hits	48	Shared Neighborhood Hits	11
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

EMR1_MOUSE
NC score	0.079181 (rank : 168)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	120	Target Neighborhood Hits	349	Shared Neighborhood Hits	48
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

UROM_HUMAN
NC score	0.078818 (rank : 169)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	120	Target Neighborhood Hits	284	Shared Neighborhood Hits	47
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

DLK_MOUSE
NC score	0.078635 (rank : 170)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	120	Target Neighborhood Hits	374	Shared Neighborhood Hits	51
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

KRA99_HUMAN
NC score	0.078576 (rank : 171)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	120	Target Neighborhood Hits	173	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

TSP4_MOUSE
NC score	0.078402 (rank : 172)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	120	Target Neighborhood Hits	276	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

UROM_MOUSE
NC score	0.078245 (rank : 173)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	120	Target Neighborhood Hits	276	Shared Neighborhood Hits	50
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

DNER_MOUSE
NC score	0.078216 (rank : 174)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	120	Target Neighborhood Hits	413	Shared Neighborhood Hits	53
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

CO6_HUMAN
NC score	0.078206 (rank : 175)	θ value	2.36792 (rank : 79)
Query Neighborhood Hits	120	Target Neighborhood Hits	331	Shared Neighborhood Hits	48
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

NID2_HUMAN
NC score	0.078203 (rank : 176)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	120	Target Neighborhood Hits	456	Shared Neighborhood Hits	57
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

DLK_HUMAN
NC score	0.078072 (rank : 177)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	120	Target Neighborhood Hits	401	Shared Neighborhood Hits	56
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

USH2A_MOUSE
NC score	0.078043 (rank : 178)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	120	Target Neighborhood Hits	626	Shared Neighborhood Hits	62
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

KR10B_HUMAN
NC score	0.077829 (rank : 179)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	120	Target Neighborhood Hits	269	Shared Neighborhood Hits	46
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KR105_HUMAN
NC score	0.077718 (rank : 180)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	120	Target Neighborhood Hits	271	Shared Neighborhood Hits	40
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR102_HUMAN
NC score	0.076934 (rank : 181)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	120	Target Neighborhood Hits	264	Shared Neighborhood Hits	46
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

LAMC3_HUMAN
NC score	0.076899 (rank : 182)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	120	Target Neighborhood Hits	588	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

CD97_HUMAN
NC score	0.076482 (rank : 183)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	120	Target Neighborhood Hits	353	Shared Neighborhood Hits	52
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

TENA_HUMAN
NC score	0.076332 (rank : 184)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	120	Target Neighborhood Hits	631	Shared Neighborhood Hits	64
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

LAMA2_HUMAN
NC score	0.076198 (rank : 185)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	120	Target Neighborhood Hits	1092	Shared Neighborhood Hits	72
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

CUBN_MOUSE
NC score	0.076011 (rank : 186)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	120	Target Neighborhood Hits	477	Shared Neighborhood Hits	58
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

GRN_MOUSE
NC score	0.075871 (rank : 187)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	120	Target Neighborhood Hits	248	Shared Neighborhood Hits	42
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

KRA44_HUMAN
NC score	0.075827 (rank : 188)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	120	Target Neighborhood Hits	162	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

TSP4_HUMAN
NC score	0.075728 (rank : 189)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	120	Target Neighborhood Hits	277	Shared Neighborhood Hits	47
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

LAMA1_MOUSE
NC score	0.075328 (rank : 190)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	120	Target Neighborhood Hits	838	Shared Neighborhood Hits	73
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

EMR2_HUMAN
NC score	0.075235 (rank : 191)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	120	Target Neighborhood Hits	345	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

LCE1C_HUMAN
NC score	0.075148 (rank : 192)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	120	Target Neighborhood Hits	65	Shared Neighborhood Hits	15
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

TSP3_MOUSE
NC score	0.075075 (rank : 193)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	120	Target Neighborhood Hits	247	Shared Neighborhood Hits	48
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

GRN_HUMAN
NC score	0.074345 (rank : 194)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	120	Target Neighborhood Hits	268	Shared Neighborhood Hits	44
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

TSP3_HUMAN
NC score	0.074289 (rank : 195)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	120	Target Neighborhood Hits	250	Shared Neighborhood Hits	47
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

KR414_HUMAN
NC score	0.074195 (rank : 196)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	120	Target Neighborhood Hits	199	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

CUBN_HUMAN
NC score	0.074108 (rank : 197)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	120	Target Neighborhood Hits	482	Shared Neighborhood Hits	56
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

TNR14_HUMAN
NC score	0.073952 (rank : 198)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	120	Target Neighborhood Hits	149	Shared Neighborhood Hits	37
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

LAMB2_MOUSE
NC score	0.073913 (rank : 199)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	120	Target Neighborhood Hits	722	Shared Neighborhood Hits	63
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

ATS16_HUMAN
NC score	0.073371 (rank : 200)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	120	Target Neighborhood Hits	208	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

LCE1E_HUMAN
NC score	0.073365 (rank : 201)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	120	Target Neighborhood Hits	53	Shared Neighborhood Hits	11
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

TR11B_HUMAN
NC score	0.073200 (rank : 202)	θ value	0.47712 (rank : 55)
Query Neighborhood Hits	120	Target Neighborhood Hits	92	Shared Neighborhood Hits	16
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

LAMC3_MOUSE
NC score	0.072971 (rank : 203)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	120	Target Neighborhood Hits	624	Shared Neighborhood Hits	64
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMA2_MOUSE
NC score	0.072824 (rank : 204)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	120	Target Neighborhood Hits	1198	Shared Neighborhood Hits	69
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

TENA_MOUSE
NC score	0.072791 (rank : 205)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	120	Target Neighborhood Hits	596	Shared Neighborhood Hits	59
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

KR109_HUMAN
NC score	0.072576 (rank : 206)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	120	Target Neighborhood Hits	226	Shared Neighborhood Hits	43
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

LCE1A_HUMAN
NC score	0.072344 (rank : 207)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	120	Target Neighborhood Hits	47	Shared Neighborhood Hits	11
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

ATS20_HUMAN
NC score	0.072292 (rank : 208)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	120	Target Neighborhood Hits	192	Shared Neighborhood Hits	41
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

AGRIN_HUMAN
NC score	0.071937 (rank : 209)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	120	Target Neighborhood Hits	582	Shared Neighborhood Hits	62
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

NAGPA_HUMAN
NC score	0.071563 (rank : 210)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	120	Target Neighborhood Hits	282	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

LRP2_HUMAN
NC score	0.071098 (rank : 211)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	120	Target Neighborhood Hits	573	Shared Neighborhood Hits	65
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

USH2A_HUMAN
NC score	0.071090 (rank : 212)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	120	Target Neighborhood Hits	600	Shared Neighborhood Hits	58
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

LDLR_HUMAN
NC score	0.070737 (rank : 213)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	120	Target Neighborhood Hits	375	Shared Neighborhood Hits	57
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

ATS17_HUMAN
NC score	0.070544 (rank : 214)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	120	Target Neighborhood Hits	194	Shared Neighborhood Hits	40
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

PROS_HUMAN
NC score	0.070162 (rank : 215)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	120	Target Neighborhood Hits	340	Shared Neighborhood Hits	48
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
NC score	0.070161 (rank : 216)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	120	Target Neighborhood Hits	330	Shared Neighborhood Hits	48
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

LRP1B_HUMAN
NC score	0.069662 (rank : 217)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	120	Target Neighborhood Hits	602	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

EGF_HUMAN
NC score	0.069484 (rank : 218)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	120	Target Neighborhood Hits	343	Shared Neighborhood Hits	55
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

LRP1_HUMAN
NC score	0.069367 (rank : 219)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	120	Target Neighborhood Hits	617	Shared Neighborhood Hits	69
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

CILP1_MOUSE
NC score	0.069066 (rank : 220)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	120	Target Neighborhood Hits	282	Shared Neighborhood Hits	32
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

KR171_HUMAN
NC score	0.068770 (rank : 221)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	120	Target Neighborhood Hits	144	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

EGF_MOUSE
NC score	0.068615 (rank : 222)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	120	Target Neighborhood Hits	358	Shared Neighborhood Hits	54
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

CO8B_MOUSE
NC score	0.068395 (rank : 223)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	120	Target Neighborhood Hits	224	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

NID2_MOUSE
NC score	0.068263 (rank : 224)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	120	Target Neighborhood Hits	338	Shared Neighborhood Hits	51
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

LAMC1_HUMAN
NC score	0.068229 (rank : 225)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	120	Target Neighborhood Hits	922	Shared Neighborhood Hits	64
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC1_MOUSE
NC score	0.067919 (rank : 226)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	120	Target Neighborhood Hits	856	Shared Neighborhood Hits	63
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

ATS9_HUMAN
NC score	0.067733 (rank : 227)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	120	Target Neighborhood Hits	219	Shared Neighborhood Hits	39
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

SEM5B_MOUSE
NC score	0.067376 (rank : 228)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	120	Target Neighborhood Hits	190	Shared Neighborhood Hits	38
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

NID1_MOUSE
NC score	0.067293 (rank : 229)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	120	Target Neighborhood Hits	335	Shared Neighborhood Hits	46
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

KRA13_HUMAN
NC score	0.067119 (rank : 230)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	120	Target Neighborhood Hits	144	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

GAS6_HUMAN
NC score	0.066913 (rank : 231)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	120	Target Neighborhood Hits	348	Shared Neighborhood Hits	50
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

ELTD1_MOUSE
NC score	0.066867 (rank : 232)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	120	Target Neighborhood Hits	288	Shared Neighborhood Hits	46
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

GAS6_MOUSE
NC score	0.066733 (rank : 233)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	120	Target Neighborhood Hits	343	Shared Neighborhood Hits	50
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

SEM5A_MOUSE
NC score	0.066685 (rank : 234)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	120	Target Neighborhood Hits	162	Shared Neighborhood Hits	33
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

EGFL7_MOUSE
NC score	0.066588 (rank : 235)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	120	Target Neighborhood Hits	287	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

ATL2_MOUSE
NC score	0.066566 (rank : 236)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	120	Target Neighborhood Hits	137	Shared Neighborhood Hits	33
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

EGFL7_HUMAN
NC score	0.066445 (rank : 237)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	120	Target Neighborhood Hits	325	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

ITB3_HUMAN
NC score	0.066389 (rank : 238)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	120	Target Neighborhood Hits	325	Shared Neighborhood Hits	59
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

CD97_MOUSE
NC score	0.066204 (rank : 239)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	120	Target Neighborhood Hits	295	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

SUSD1_HUMAN
NC score	0.066167 (rank : 240)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	120	Target Neighborhood Hits	285	Shared Neighborhood Hits	40
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

SEM5B_HUMAN
NC score	0.066083 (rank : 241)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	120	Target Neighborhood Hits	178	Shared Neighborhood Hits	37
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

NFX1_HUMAN
NC score	0.066039 (rank : 242)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	120	Target Neighborhood Hits	405	Shared Neighborhood Hits	40
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

NID1_HUMAN
NC score	0.065915 (rank : 243)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	120	Target Neighborhood Hits	329	Shared Neighborhood Hits	46
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

LRP1B_MOUSE
NC score	0.065573 (rank : 244)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	120	Target Neighborhood Hits	606	Shared Neighborhood Hits	62
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

ATL2_HUMAN
NC score	0.065467 (rank : 245)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	120	Target Neighborhood Hits	125	Shared Neighborhood Hits	32
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

LAMB1_MOUSE
NC score	0.065070 (rank : 246)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	120	Target Neighborhood Hits	919	Shared Neighborhood Hits	54
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

SEM5A_HUMAN
NC score	0.064742 (rank : 247)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	120	Target Neighborhood Hits	177	Shared Neighborhood Hits	35
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

UNC5B_HUMAN
NC score	0.064528 (rank : 248)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	120	Target Neighborhood Hits	225	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5B_MOUSE
NC score	0.064467 (rank : 249)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	120	Target Neighborhood Hits	226	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

ITB3_MOUSE
NC score	0.064344 (rank : 250)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	120	Target Neighborhood Hits	319	Shared Neighborhood Hits	50
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

MATN3_HUMAN
NC score	0.064245 (rank : 251)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	120	Target Neighborhood Hits	268	Shared Neighborhood Hits	43
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MUC5B_HUMAN
NC score	0.064233 (rank : 252)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	120	Target Neighborhood Hits	1020	Shared Neighborhood Hits	61
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

ERBB3_MOUSE
NC score	0.064166 (rank : 253)	θ value	0.21417 (rank : 42)
Query Neighborhood Hits	120	Target Neighborhood Hits	898	Shared Neighborhood Hits	45
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

NAGPA_MOUSE
NC score	0.064043 (rank : 254)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	120	Target Neighborhood Hits	308	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

CO8B_HUMAN
NC score	0.064035 (rank : 255)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	120	Target Neighborhood Hits	199	Shared Neighborhood Hits	38
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

ERBB3_HUMAN
NC score	0.063023 (rank : 256)	θ value	0.62314 (rank : 56)
Query Neighborhood Hits	120	Target Neighborhood Hits	918	Shared Neighborhood Hits	46
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

KR10C_HUMAN
NC score	0.062739 (rank : 257)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	120	Target Neighborhood Hits	219	Shared Neighborhood Hits	40
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

LAMA3_MOUSE
NC score	0.062408 (rank : 258)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	120	Target Neighborhood Hits	859	Shared Neighborhood Hits	68
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

MATN3_MOUSE
NC score	0.062046 (rank : 259)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	120	Target Neighborhood Hits	261	Shared Neighborhood Hits	44
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

LAMC2_MOUSE
NC score	0.061650 (rank : 260)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	120	Target Neighborhood Hits	614	Shared Neighborhood Hits	59
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

EGFL8_HUMAN
NC score	0.061403 (rank : 261)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	120	Target Neighborhood Hits	270	Shared Neighborhood Hits	39
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

LAMB3_MOUSE
NC score	0.061324 (rank : 262)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	120	Target Neighborhood Hits	444	Shared Neighborhood Hits	52
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LRP8_MOUSE
NC score	0.060765 (rank : 263)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	120	Target Neighborhood Hits	385	Shared Neighborhood Hits	54
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LDLR_MOUSE
NC score	0.060705 (rank : 264)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	120	Target Neighborhood Hits	382	Shared Neighborhood Hits	53
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

KR410_HUMAN
NC score	0.060451 (rank : 265)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	120	Target Neighborhood Hits	156	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

UNC5A_MOUSE
NC score	0.060316 (rank : 266)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	120	Target Neighborhood Hits	203	Shared Neighborhood Hits	27
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

ITB5_MOUSE
NC score	0.060107 (rank : 267)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	120	Target Neighborhood Hits	329	Shared Neighborhood Hits	53
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

LAMB1_HUMAN
NC score	0.060057 (rank : 268)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	120	Target Neighborhood Hits	1018	Shared Neighborhood Hits	54
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

MATN4_HUMAN
NC score	0.060045 (rank : 269)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	120	Target Neighborhood Hits	287	Shared Neighborhood Hits	46
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

TNR16_HUMAN
NC score	0.059721 (rank : 270)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	120	Target Neighborhood Hits	183	Shared Neighborhood Hits	35
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

CO7_HUMAN
NC score	0.059687 (rank : 271)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	120	Target Neighborhood Hits	278	Shared Neighborhood Hits	48
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

EGFL8_MOUSE
NC score	0.059578 (rank : 272)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	120	Target Neighborhood Hits	266	Shared Neighborhood Hits	39
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

TNR25_HUMAN
NC score	0.059137 (rank : 273)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	120	Target Neighborhood Hits	172	Shared Neighborhood Hits	35
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TIE2_MOUSE
NC score	0.059058 (rank : 274)	θ value	0.279714 (rank : 46)
Query Neighborhood Hits	120	Target Neighborhood Hits	1204	Shared Neighborhood Hits	67
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

LAMC2_HUMAN
NC score	0.059009 (rank : 275)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	120	Target Neighborhood Hits	715	Shared Neighborhood Hits	56
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

VLDLR_HUMAN
NC score	0.058955 (rank : 276)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	120	Target Neighborhood Hits	383	Shared Neighborhood Hits	48
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

ITB5_HUMAN
NC score	0.058869 (rank : 277)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	120	Target Neighborhood Hits	310	Shared Neighborhood Hits	54
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

FREM2_MOUSE
NC score	0.058540 (rank : 278)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	120	Target Neighborhood Hits	73	Shared Neighborhood Hits	2
SwissProt Accessions	Q6NVD0, Q4W2Q5, Q5H8C0, Q811G9, Q8C4G5, Q8CD46	Gene names	Frem2, Nv1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog) (NV domain-containing protein 1).

TIE1_HUMAN
NC score	0.058517 (rank : 279)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	120	Target Neighborhood Hits	1241	Shared Neighborhood Hits	67
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

ATS12_MOUSE
NC score	0.058508 (rank : 280)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	120	Target Neighborhood Hits	220	Shared Neighborhood Hits	33
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

VLDLR_MOUSE
NC score	0.058381 (rank : 281)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	120	Target Neighborhood Hits	360	Shared Neighborhood Hits	47
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

THSD1_MOUSE
NC score	0.058214 (rank : 282)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	120	Target Neighborhood Hits	153	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

FREM2_HUMAN
NC score	0.058127 (rank : 283)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	120	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q5SZK8, Q4QQG1, Q5H9N8, Q5T6Q1, Q6N057, Q6ZSB4, Q7Z305, Q7Z341	Gene names	FREM2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog).

UNC5C_HUMAN
NC score	0.057789 (rank : 284)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	120	Target Neighborhood Hits	226	Shared Neighborhood Hits	26
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

ITB4_HUMAN
NC score	0.057765 (rank : 285)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	120	Target Neighborhood Hits	458	Shared Neighborhood Hits	54
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

SORL_MOUSE
NC score	0.057628 (rank : 286)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	120	Target Neighborhood Hits	439	Shared Neighborhood Hits	63
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

UNC5C_MOUSE
NC score	0.057615 (rank : 287)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	120	Target Neighborhood Hits	225	Shared Neighborhood Hits	26
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

HHIP_MOUSE
NC score	0.057492 (rank : 288)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	120	Target Neighborhood Hits	219	Shared Neighborhood Hits	34
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

MATN4_MOUSE
NC score	0.057474 (rank : 289)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	120	Target Neighborhood Hits	277	Shared Neighborhood Hits	42
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

HHIP_HUMAN
NC score	0.057454 (rank : 290)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	120	Target Neighborhood Hits	249	Shared Neighborhood Hits	37
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

ATL3_HUMAN
NC score	0.056944 (rank : 291)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	120	Target Neighborhood Hits	414	Shared Neighborhood Hits	37
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

LRP8_HUMAN
NC score	0.056528 (rank : 292)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	120	Target Neighborhood Hits	346	Shared Neighborhood Hits	50
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

ATS12_HUMAN
NC score	0.056192 (rank : 293)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	120	Target Neighborhood Hits	251	Shared Neighborhood Hits	32
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS18_HUMAN
NC score	0.056154 (rank : 294)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	120	Target Neighborhood Hits	169	Shared Neighborhood Hits	33
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ZNFX1_HUMAN
NC score	0.056130 (rank : 295)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	120	Target Neighborhood Hits	308	Shared Neighborhood Hits	32
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

THSD1_HUMAN
NC score	0.056062 (rank : 296)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	120	Target Neighborhood Hits	136	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

ITB7_HUMAN
NC score	0.055652 (rank : 297)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	120	Target Neighborhood Hits	290	Shared Neighborhood Hits	50
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

ELTD1_HUMAN
NC score	0.055620 (rank : 298)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	120	Target Neighborhood Hits	269	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

TNR26_MOUSE
NC score	0.055396 (rank : 299)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	120	Target Neighborhood Hits	106	Shared Neighborhood Hits	27
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TIE1_MOUSE
NC score	0.055215 (rank : 300)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	120	Target Neighborhood Hits	1266	Shared Neighborhood Hits	62
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

KRA15_HUMAN
NC score	0.055190 (rank : 301)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	120	Target Neighborhood Hits	126	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

ATL5_HUMAN
NC score	0.055164 (rank : 302)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	120	Target Neighborhood Hits	103	Shared Neighborhood Hits	25
SwissProt Accessions	Q6ZMM2, Q8IW95	Gene names	ADAMTSL5, THSD6
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 5 precursor (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6).

LRP4_HUMAN
NC score	0.055097 (rank : 303)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	120	Target Neighborhood Hits	355	Shared Neighborhood Hits	53
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

ITB6_MOUSE
NC score	0.055014 (rank : 304)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	120	Target Neighborhood Hits	341	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

TNR9_HUMAN
NC score	0.054931 (rank : 305)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	120	Target Neighborhood Hits	166	Shared Neighborhood Hits	33
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

ATS18_MOUSE
NC score	0.054916 (rank : 306)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	120	Target Neighborhood Hits	163	Shared Neighborhood Hits	30
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

PGBM_MOUSE
NC score	0.054895 (rank : 307)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	120	Target Neighborhood Hits	1073	Shared Neighborhood Hits	70
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

UNC5D_HUMAN
NC score	0.054816 (rank : 308)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	120	Target Neighborhood Hits	267	Shared Neighborhood Hits	28
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5D_MOUSE
NC score	0.054600 (rank : 309)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	120	Target Neighborhood Hits	268	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

LAMB3_HUMAN
NC score	0.054561 (rank : 310)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	120	Target Neighborhood Hits	461	Shared Neighborhood Hits	42
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LRP4_MOUSE
NC score	0.054501 (rank : 311)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	120	Target Neighborhood Hits	351	Shared Neighborhood Hits	54
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

CD248_HUMAN
NC score	0.054387 (rank : 312)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	120	Target Neighborhood Hits	679	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

ATS19_MOUSE
NC score	0.054270 (rank : 313)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	120	Target Neighborhood Hits	188	Shared Neighborhood Hits	29
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ERBB4_HUMAN
NC score	0.054220 (rank : 314)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	120	Target Neighborhood Hits	910	Shared Neighborhood Hits	41
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

SORL_HUMAN
NC score	0.054179 (rank : 315)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	120	Target Neighborhood Hits	440	Shared Neighborhood Hits	56
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

TNR16_MOUSE
NC score	0.054090 (rank : 316)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	120	Target Neighborhood Hits	178	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

EGFR_MOUSE
NC score	0.054075 (rank : 317)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	120	Target Neighborhood Hits	927	Shared Neighborhood Hits	46
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

ATS13_HUMAN
NC score	0.053802 (rank : 318)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	120	Target Neighborhood Hits	238	Shared Neighborhood Hits	32
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ITB1_HUMAN
NC score	0.053414 (rank : 319)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	120	Target Neighborhood Hits	298	Shared Neighborhood Hits	51
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB7_MOUSE
NC score	0.053324 (rank : 320)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	120	Target Neighborhood Hits	277	Shared Neighborhood Hits	44
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

TNR9_MOUSE
NC score	0.053088 (rank : 321)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	120	Target Neighborhood Hits	137	Shared Neighborhood Hits	21
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

ATS3_HUMAN
NC score	0.053069 (rank : 322)	θ value	4.03905 (rank : 91)
Query Neighborhood Hits	120	Target Neighborhood Hits	179	Shared Neighborhood Hits	37
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

CI094_HUMAN
NC score	0.052890 (rank : 323)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	120	Target Neighborhood Hits	310	Shared Neighborhood Hits	29
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

LAMA4_MOUSE
NC score	0.052842 (rank : 324)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	120	Target Neighborhood Hits	584	Shared Neighborhood Hits	51
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

ITB2_MOUSE
NC score	0.052830 (rank : 325)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	120	Target Neighborhood Hits	326	Shared Neighborhood Hits	49
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ATS13_MOUSE
NC score	0.052734 (rank : 326)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	120	Target Neighborhood Hits	227	Shared Neighborhood Hits	36
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

CD248_MOUSE
NC score	0.052674 (rank : 327)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	120	Target Neighborhood Hits	578	Shared Neighborhood Hits	42
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

KRA11_HUMAN
NC score	0.052627 (rank : 328)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	120	Target Neighborhood Hits	155	Shared Neighborhood Hits	24
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

TECTA_MOUSE
NC score	0.052596 (rank : 329)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	120	Target Neighborhood Hits	244	Shared Neighborhood Hits	46
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

ATS2_HUMAN
NC score	0.052396 (rank : 330)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	120	Target Neighborhood Hits	179	Shared Neighborhood Hits	34
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

WISP2_HUMAN
NC score	0.051952 (rank : 331)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	120	Target Neighborhood Hits	126	Shared Neighborhood Hits	36
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

MT3_MOUSE
NC score	0.051874 (rank : 332)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	120	Target Neighborhood Hits	68	Shared Neighborhood Hits	17
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

ZNFX1_MOUSE
NC score	0.051560 (rank : 333)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	120	Target Neighborhood Hits	407	Shared Neighborhood Hits	34
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

TDGF1_MOUSE
NC score	0.051334 (rank : 334)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	120	Target Neighborhood Hits	146	Shared Neighborhood Hits	31
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

ITB1_MOUSE
NC score	0.051302 (rank : 335)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	120	Target Neighborhood Hits	283	Shared Neighborhood Hits	49
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

TNR5_HUMAN
NC score	0.051250 (rank : 336)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	120	Target Neighborhood Hits	102	Shared Neighborhood Hits	22
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TIE2_HUMAN
NC score	0.051188 (rank : 337)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	120	Target Neighborhood Hits	1192	Shared Neighborhood Hits	61
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

FREM3_HUMAN
NC score	0.051187 (rank : 338)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	120	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	P0C091	Gene names	FREM3
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor.

ATRN_MOUSE
NC score	0.051047 (rank : 339)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	120	Target Neighborhood Hits	519	Shared Neighborhood Hits	52
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

KR10A_HUMAN
NC score	0.050937 (rank : 340)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	120	Target Neighborhood Hits	232	Shared Neighborhood Hits	42
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

FREM3_MOUSE
NC score	0.050908 (rank : 341)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	120	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q5H8B9	Gene names	Frem3, Nv2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor (NV domain- containing protein 2).

CHRD_HUMAN
NC score	0.050869 (rank : 342)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	120	Target Neighborhood Hits	102	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

EGFR_HUMAN
NC score	0.050675 (rank : 343)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	120	Target Neighborhood Hits	939	Shared Neighborhood Hits	41
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

ITB6_HUMAN
NC score	0.050633 (rank : 344)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	120	Target Neighborhood Hits	318	Shared Neighborhood Hits	48
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

LCE2A_HUMAN
NC score	0.050558 (rank : 345)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	120	Target Neighborhood Hits	50	Shared Neighborhood Hits	11
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

ATS19_HUMAN
NC score	0.050546 (rank : 346)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	120	Target Neighborhood Hits	203	Shared Neighborhood Hits	29
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

LAMA4_HUMAN
NC score	0.050287 (rank : 347)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	120	Target Neighborhood Hits	708	Shared Neighborhood Hits	52
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

NTNG2_HUMAN
NC score	0.050220 (rank : 348)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	120	Target Neighborhood Hits	276	Shared Neighborhood Hits	47
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

ZAN_HUMAN
NC score	0.050034 (rank : 349)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	120	Target Neighborhood Hits	679	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

TNR22_MOUSE
NC score	0.049040 (rank : 350)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	120	Target Neighborhood Hits	97	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

EPHB2_HUMAN
NC score	0.035593 (rank : 351)	θ value	0.813845 (rank : 59)
Query Neighborhood Hits	120	Target Neighborhood Hits	983	Shared Neighborhood Hits	31
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB2_MOUSE
NC score	0.035573 (rank : 352)	θ value	0.813845 (rank : 60)
Query Neighborhood Hits	120	Target Neighborhood Hits	982	Shared Neighborhood Hits	31
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

VEGFD_HUMAN
NC score	0.034396 (rank : 353)	θ value	3.0926 (rank : 89)
Query Neighborhood Hits	120	Target Neighborhood Hits	48	Shared Neighborhood Hits	9
SwissProt Accessions	O43915	Gene names	FIGF, VEGFD
Domain Architecture
Description	Vascular endothelial growth factor D precursor (VEGF-D) (c-fos-induced growth factor) (FIGF).

WISP1_HUMAN
NC score	0.034215 (rank : 354)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	120	Target Neighborhood Hits	121	Shared Neighborhood Hits	31
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

HIRP3_HUMAN
NC score	0.028505 (rank : 355)	θ value	1.06291 (rank : 67)
Query Neighborhood Hits	120	Target Neighborhood Hits	323	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

VEGFD_MOUSE
NC score	0.025064 (rank : 356)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	120	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	P97946	Gene names	Figf, Vegfd
Domain Architecture
Description	Vascular endothelial growth factor D precursor (VEGF-D) (c-fos-induced growth factor) (FIGF).

IDLC_HUMAN
NC score	0.024066 (rank : 357)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	120	Target Neighborhood Hits	348	Shared Neighborhood Hits	6
SwissProt Accessions	O14645, Q5TGH0, Q7L0I5	Gene names	DNALI1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal) (hp28).

IDLC_MOUSE
NC score	0.023905 (rank : 358)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	120	Target Neighborhood Hits	321	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BVN8	Gene names	Dnali1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal).

LHX4_MOUSE
NC score	0.019811 (rank : 359)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	120	Target Neighborhood Hits	457	Shared Neighborhood Hits	10
SwissProt Accessions	P53776, O08916, Q9R280	Gene names	Lhx4, Gsh-4, Gsh4
Domain Architecture
Description	LIM/homeobox protein Lhx4.

LHX4_HUMAN
NC score	0.019803 (rank : 360)	θ value	4.03905 (rank : 94)
Query Neighborhood Hits	120	Target Neighborhood Hits	455	Shared Neighborhood Hits	10
SwissProt Accessions	Q969G2, Q8NHE0, Q8TCJ1, Q8WWX2, Q969W2	Gene names	LHX4
Domain Architecture
Description	LIM/homeobox protein Lhx4.

ATRX_HUMAN
NC score	0.018997 (rank : 361)	θ value	0.21417 (rank : 41)
Query Neighborhood Hits	120	Target Neighborhood Hits	842	Shared Neighborhood Hits	10
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

ZC11A_MOUSE
NC score	0.016065 (rank : 362)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	120	Target Neighborhood Hits	216	Shared Neighborhood Hits	5
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

MDC1_HUMAN
NC score	0.010149 (rank : 363)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	120	Target Neighborhood Hits	1446	Shared Neighborhood Hits	18
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

NEIL1_MOUSE
NC score	0.010094 (rank : 364)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	120	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K4Q6, Q80V58, Q9CYT9	Gene names	Neil1, Nei1
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 1 (EC 3.2.2.-) (EC 4.2.99.18) (Nei-like 1) (DNA glycosylase/AP lyase Neil1) (DNA-(apurinic or apyrimidinic site) lyase Neil1) (NEH1).

CTTB2_HUMAN
NC score	0.010049 (rank : 365)	θ value	2.36792 (rank : 80)
Query Neighborhood Hits	120	Target Neighborhood Hits	1061	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

CJ078_MOUSE
NC score	0.009127 (rank : 366)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	120	Target Neighborhood Hits	559	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

LHX3_HUMAN
NC score	0.007713 (rank : 367)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	120	Target Neighborhood Hits	474	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UBR4, Q9NZB5, Q9P0I8, Q9P0I9	Gene names	LHX3
Domain Architecture
Description	LIM/homeobox protein Lhx3.

CCD55_HUMAN
NC score	0.007552 (rank : 368)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	120	Target Neighborhood Hits	513	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

MRCKB_HUMAN
NC score	0.006117 (rank : 369)	θ value	2.36792 (rank : 83)
Query Neighborhood Hits	120	Target Neighborhood Hits	2239	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MRCKB_MOUSE
NC score	0.005621 (rank : 370)	θ value	6.88961 (rank : 108)
Query Neighborhood Hits	120	Target Neighborhood Hits	2180	Shared Neighborhood Hits	25
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

ATBF1_MOUSE
NC score	0.002025 (rank : 371)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	120	Target Neighborhood Hits	1841	Shared Neighborhood Hits	18
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

ATBF1_HUMAN
NC score	0.001452 (rank : 372)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	120	Target Neighborhood Hits	1547	Shared Neighborhood Hits	11
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).