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Network neighborhood for query Sequence : TECTA_MOUSE

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TECTA_MOUSE
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TECTA_HUMAN
θ value	0 (rank : 1)	NC score	0.994904 (rank : 2)
Query Neighborhood Hits	244	Target Neighborhood Hits	239	Shared Neighborhood Hits	209
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

TECTA_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	244	Target Neighborhood Hits	244	Shared Neighborhood Hits	244
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

ZAN_HUMAN
θ value	1.27474e-179 (rank : 3)	NC score	0.677359 (rank : 3)
Query Neighborhood Hits	244	Target Neighborhood Hits	679	Shared Neighborhood Hits	176
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ZAN_MOUSE
θ value	2.04937e-153 (rank : 4)	NC score	0.614464 (rank : 6)
Query Neighborhood Hits	244	Target Neighborhood Hits	808	Shared Neighborhood Hits	206
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

VWF_MOUSE
θ value	1.31376e-75 (rank : 5)	NC score	0.608033 (rank : 9)
Query Neighborhood Hits	244	Target Neighborhood Hits	381	Shared Neighborhood Hits	150
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

SSPO_MOUSE
θ value	4.22625e-74 (rank : 6)	NC score	0.483048 (rank : 16)
Query Neighborhood Hits	244	Target Neighborhood Hits	800	Shared Neighborhood Hits	190
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

VWF_HUMAN
θ value	1.19101e-68 (rank : 7)	NC score	0.611773 (rank : 7)
Query Neighborhood Hits	244	Target Neighborhood Hits	396	Shared Neighborhood Hits	152
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

MUC2_HUMAN
θ value	2.7521e-57 (rank : 8)	NC score	0.545068 (rank : 12)
Query Neighborhood Hits	244	Target Neighborhood Hits	906	Shared Neighborhood Hits	121
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

UROM_HUMAN
θ value	3.0428e-56 (rank : 9)	NC score	0.527963 (rank : 14)
Query Neighborhood Hits	244	Target Neighborhood Hits	284	Shared Neighborhood Hits	156
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_MOUSE
θ value	6.77864e-56 (rank : 10)	NC score	0.537913 (rank : 13)
Query Neighborhood Hits	244	Target Neighborhood Hits	276	Shared Neighborhood Hits	154
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

GP2_MOUSE
θ value	8.85319e-56 (rank : 11)	NC score	0.609436 (rank : 8)
Query Neighborhood Hits	244	Target Neighborhood Hits	29	Shared Neighborhood Hits	23
SwissProt Accessions	Q9D733	Gene names	Gp2
Domain Architecture	No domain graphic available
Description	Pancreatic secretory granule membrane major glycoprotein GP2 precursor (Pancreatic zymogen granule membrane protein GP-2).

MUC5B_HUMAN
θ value	4.85792e-54 (rank : 12)	NC score	0.586198 (rank : 11)
Query Neighborhood Hits	244	Target Neighborhood Hits	1020	Shared Neighborhood Hits	158
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

GP2_HUMAN
θ value	9.16162e-53 (rank : 13)	NC score	0.607696 (rank : 10)
Query Neighborhood Hits	244	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	P55259, Q13338, Q9UIF1	Gene names	GP2
Domain Architecture
Description	Pancreatic secretory granule membrane major glycoprotein GP2 precursor (Pancreatic zymogen granule membrane protein GP-2) (ZAP75).

BMPER_MOUSE
θ value	1.19932e-44 (rank : 14)	NC score	0.620300 (rank : 5)
Query Neighborhood Hits	244	Target Neighborhood Hits	194	Shared Neighborhood Hits	105
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

BMPER_HUMAN
θ value	2.04573e-44 (rank : 15)	NC score	0.620348 (rank : 4)
Query Neighborhood Hits	244	Target Neighborhood Hits	175	Shared Neighborhood Hits	94
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

NID2_MOUSE
θ value	8.36355e-22 (rank : 16)	NC score	0.346774 (rank : 24)
Query Neighborhood Hits	244	Target Neighborhood Hits	338	Shared Neighborhood Hits	146
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NID2_HUMAN
θ value	1.09232e-21 (rank : 17)	NC score	0.350101 (rank : 23)
Query Neighborhood Hits	244	Target Neighborhood Hits	456	Shared Neighborhood Hits	153
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID1_MOUSE
θ value	4.29542e-18 (rank : 18)	NC score	0.336772 (rank : 25)
Query Neighborhood Hits	244	Target Neighborhood Hits	335	Shared Neighborhood Hits	146
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

ZP4_HUMAN
θ value	1.24977e-17 (rank : 19)	NC score	0.413017 (rank : 20)
Query Neighborhood Hits	244	Target Neighborhood Hits	36	Shared Neighborhood Hits	21
SwissProt Accessions	Q12836	Gene names	ZP4, ZPB
Domain Architecture
Description	Zona pellucida sperm-binding protein 4 precursor (Zona pellucida sperm-binding protein B).

TECTB_MOUSE
θ value	2.13179e-17 (rank : 20)	NC score	0.485753 (rank : 15)
Query Neighborhood Hits	244	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	O08524	Gene names	Tectb
Domain Architecture
Description	Beta-tectorin precursor.

CUZD1_HUMAN
θ value	3.07829e-16 (rank : 21)	NC score	0.323495 (rank : 27)
Query Neighborhood Hits	244	Target Neighborhood Hits	89	Shared Neighborhood Hits	34
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

TECTB_HUMAN
θ value	1.16975e-15 (rank : 22)	NC score	0.480893 (rank : 17)
Query Neighborhood Hits	244	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q96PL2	Gene names	TECTB
Domain Architecture
Description	Beta-tectorin precursor.

CUZD1_MOUSE
θ value	3.40345e-15 (rank : 23)	NC score	0.322732 (rank : 29)
Query Neighborhood Hits	244	Target Neighborhood Hits	91	Shared Neighborhood Hits	33
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

DMBT1_HUMAN
θ value	9.90251e-15 (rank : 24)	NC score	0.206890 (rank : 140)
Query Neighborhood Hits	244	Target Neighborhood Hits	152	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

NID1_HUMAN
θ value	9.90251e-15 (rank : 25)	NC score	0.329999 (rank : 26)
Query Neighborhood Hits	244	Target Neighborhood Hits	329	Shared Neighborhood Hits	146
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

ZP2_HUMAN
θ value	6.41864e-14 (rank : 26)	NC score	0.380529 (rank : 22)
Query Neighborhood Hits	244	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	Q05996	Gene names	ZP2, ZPA
Domain Architecture
Description	Zona pellucida sperm-binding protein 2 precursor (Zona pellucida glycoprotein ZP2) (Zona pellucida protein A).

DMBT1_MOUSE
θ value	3.18553e-13 (rank : 27)	NC score	0.206558 (rank : 141)
Query Neighborhood Hits	244	Target Neighborhood Hits	134	Shared Neighborhood Hits	35
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

ZP2_MOUSE
θ value	4.16044e-13 (rank : 28)	NC score	0.403307 (rank : 21)
Query Neighborhood Hits	244	Target Neighborhood Hits	28	Shared Neighborhood Hits	21
SwissProt Accessions	P20239	Gene names	Zp2, Zp-2, Zpa
Domain Architecture
Description	Zona pellucida sperm-binding protein 2 precursor (Zona pellucida glycoprotein ZP2) (Zona pellucida protein A).

UROL1_HUMAN
θ value	5.43371e-13 (rank : 29)	NC score	0.431804 (rank : 19)
Query Neighborhood Hits	244	Target Neighborhood Hits	213	Shared Neighborhood Hits	104
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

UROL1_MOUSE
θ value	6.00763e-12 (rank : 30)	NC score	0.441720 (rank : 18)
Query Neighborhood Hits	244	Target Neighborhood Hits	235	Shared Neighborhood Hits	116
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

ZP1_HUMAN
θ value	1.29631e-06 (rank : 31)	NC score	0.309368 (rank : 31)
Query Neighborhood Hits	244	Target Neighborhood Hits	39	Shared Neighborhood Hits	19
SwissProt Accessions	P60852	Gene names	ZP1
Domain Architecture	No domain graphic available
Description	Zona pellucida sperm-binding protein 1 precursor (Zona pellucida glycoprotein 1) (Zp-1).

ZP1_MOUSE
θ value	1.69304e-06 (rank : 32)	NC score	0.317386 (rank : 30)
Query Neighborhood Hits	244	Target Neighborhood Hits	43	Shared Neighborhood Hits	22
SwissProt Accessions	Q62005, Q62016	Gene names	Zp1
Domain Architecture
Description	Zona pellucida sperm-binding protein 1 precursor (Zona pellucida glycoprotein 1) (Zp-1).

SUSD2_HUMAN
θ value	4.92598e-06 (rank : 33)	NC score	0.251924 (rank : 79)
Query Neighborhood Hits	244	Target Neighborhood Hits	99	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

SUSD2_MOUSE
θ value	8.40245e-06 (rank : 34)	NC score	0.253152 (rank : 77)
Query Neighborhood Hits	244	Target Neighborhood Hits	104	Shared Neighborhood Hits	24
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

STAB2_MOUSE
θ value	2.44474e-05 (rank : 35)	NC score	0.262246 (rank : 64)
Query Neighborhood Hits	244	Target Neighborhood Hits	528	Shared Neighborhood Hits	184
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

PCSK5_MOUSE
θ value	5.44631e-05 (rank : 36)	NC score	0.226567 (rank : 113)
Query Neighborhood Hits	244	Target Neighborhood Hits	613	Shared Neighborhood Hits	187
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

FBLN2_HUMAN
θ value	0.000158464 (rank : 37)	NC score	0.282508 (rank : 36)
Query Neighborhood Hits	244	Target Neighborhood Hits	392	Shared Neighborhood Hits	167
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

STAB1_MOUSE
θ value	0.000461057 (rank : 38)	NC score	0.263613 (rank : 57)
Query Neighborhood Hits	244	Target Neighborhood Hits	566	Shared Neighborhood Hits	193
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

PCSK6_HUMAN
θ value	0.000602161 (rank : 39)	NC score	0.137668 (rank : 247)
Query Neighborhood Hits	244	Target Neighborhood Hits	298	Shared Neighborhood Hits	106
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

LRP1_HUMAN
θ value	0.000786445 (rank : 40)	NC score	0.261143 (rank : 66)
Query Neighborhood Hits	244	Target Neighborhood Hits	617	Shared Neighborhood Hits	204
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP1B_HUMAN
θ value	0.00102713 (rank : 41)	NC score	0.262772 (rank : 62)
Query Neighborhood Hits	244	Target Neighborhood Hits	602	Shared Neighborhood Hits	198
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

TRBM_HUMAN
θ value	0.00102713 (rank : 42)	NC score	0.280930 (rank : 37)
Query Neighborhood Hits	244	Target Neighborhood Hits	339	Shared Neighborhood Hits	170
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

MATN3_MOUSE
θ value	0.00134147 (rank : 43)	NC score	0.257015 (rank : 73)
Query Neighborhood Hits	244	Target Neighborhood Hits	261	Shared Neighborhood Hits	133
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

LRP1B_MOUSE
θ value	0.00175202 (rank : 44)	NC score	0.258944 (rank : 70)
Query Neighborhood Hits	244	Target Neighborhood Hits	606	Shared Neighborhood Hits	197
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

MATN3_HUMAN
θ value	0.00175202 (rank : 45)	NC score	0.263145 (rank : 60)
Query Neighborhood Hits	244	Target Neighborhood Hits	268	Shared Neighborhood Hits	133
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

ZP3_HUMAN
θ value	0.00175202 (rank : 46)	NC score	0.179437 (rank : 177)
Query Neighborhood Hits	244	Target Neighborhood Hits	22	Shared Neighborhood Hits	17
SwissProt Accessions	P21754, Q06633	Gene names	ZP3, ZP3A, ZPC
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 precursor (Zona pellucida glycoprotein ZP3) (Zona pellucida protein C) (Sperm receptor) (ZP3A/ZP3B).

MATN2_MOUSE
θ value	0.00228821 (rank : 47)	NC score	0.272024 (rank : 47)
Query Neighborhood Hits	244	Target Neighborhood Hits	356	Shared Neighborhood Hits	157
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MATN4_MOUSE
θ value	0.00228821 (rank : 48)	NC score	0.253499 (rank : 76)
Query Neighborhood Hits	244	Target Neighborhood Hits	277	Shared Neighborhood Hits	135
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

NELL1_HUMAN
θ value	0.00228821 (rank : 49)	NC score	0.323321 (rank : 28)
Query Neighborhood Hits	244	Target Neighborhood Hits	451	Shared Neighborhood Hits	189
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

FBLN3_MOUSE
θ value	0.00390308 (rank : 50)	NC score	0.261007 (rank : 67)
Query Neighborhood Hits	244	Target Neighborhood Hits	279	Shared Neighborhood Hits	146
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

NELL2_MOUSE
θ value	0.00390308 (rank : 51)	NC score	0.308305 (rank : 32)
Query Neighborhood Hits	244	Target Neighborhood Hits	436	Shared Neighborhood Hits	180
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

STAB2_HUMAN
θ value	0.00390308 (rank : 52)	NC score	0.252465 (rank : 78)
Query Neighborhood Hits	244	Target Neighborhood Hits	534	Shared Neighborhood Hits	193
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

FBLN3_HUMAN
θ value	0.00509761 (rank : 53)	NC score	0.264471 (rank : 55)
Query Neighborhood Hits	244	Target Neighborhood Hits	293	Shared Neighborhood Hits	153
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

LRP5_HUMAN
θ value	0.00509761 (rank : 54)	NC score	0.191242 (rank : 155)
Query Neighborhood Hits	244	Target Neighborhood Hits	224	Shared Neighborhood Hits	109
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

EGF_HUMAN
θ value	0.00665767 (rank : 55)	NC score	0.278127 (rank : 43)
Query Neighborhood Hits	244	Target Neighborhood Hits	343	Shared Neighborhood Hits	162
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

MEGF6_HUMAN
θ value	0.00665767 (rank : 56)	NC score	0.280899 (rank : 38)
Query Neighborhood Hits	244	Target Neighborhood Hits	671	Shared Neighborhood Hits	207
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

PCSK5_HUMAN
θ value	0.00665767 (rank : 57)	NC score	0.141445 (rank : 241)
Query Neighborhood Hits	244	Target Neighborhood Hits	291	Shared Neighborhood Hits	121
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

AGRIN_HUMAN
θ value	0.00869519 (rank : 58)	NC score	0.188944 (rank : 159)
Query Neighborhood Hits	244	Target Neighborhood Hits	582	Shared Neighborhood Hits	174
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

NOTC1_HUMAN
θ value	0.00869519 (rank : 59)	NC score	0.225688 (rank : 115)
Query Neighborhood Hits	244	Target Neighborhood Hits	906	Shared Neighborhood Hits	197
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

SREC2_HUMAN
θ value	0.00869519 (rank : 60)	NC score	0.217556 (rank : 126)
Query Neighborhood Hits	244	Target Neighborhood Hits	645	Shared Neighborhood Hits	178
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

LRP2_HUMAN
θ value	0.0113563 (rank : 61)	NC score	0.265976 (rank : 53)
Query Neighborhood Hits	244	Target Neighborhood Hits	573	Shared Neighborhood Hits	199
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LTBP2_MOUSE
θ value	0.0113563 (rank : 62)	NC score	0.255892 (rank : 74)
Query Neighborhood Hits	244	Target Neighborhood Hits	617	Shared Neighborhood Hits	188
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP2_HUMAN
θ value	0.0148317 (rank : 63)	NC score	0.262119 (rank : 65)
Query Neighborhood Hits	244	Target Neighborhood Hits	552	Shared Neighborhood Hits	189
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

MATN2_HUMAN
θ value	0.0148317 (rank : 64)	NC score	0.260773 (rank : 68)
Query Neighborhood Hits	244	Target Neighborhood Hits	365	Shared Neighborhood Hits	155
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

VLDLR_MOUSE
θ value	0.0148317 (rank : 65)	NC score	0.247103 (rank : 88)
Query Neighborhood Hits	244	Target Neighborhood Hits	360	Shared Neighborhood Hits	152
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

CD248_HUMAN
θ value	0.0193708 (rank : 66)	NC score	0.250716 (rank : 80)
Query Neighborhood Hits	244	Target Neighborhood Hits	679	Shared Neighborhood Hits	150
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

FBLN2_MOUSE
θ value	0.0193708 (rank : 67)	NC score	0.283891 (rank : 34)
Query Neighborhood Hits	244	Target Neighborhood Hits	505	Shared Neighborhood Hits	168
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

LAMA1_MOUSE
θ value	0.0193708 (rank : 68)	NC score	0.145204 (rank : 230)
Query Neighborhood Hits	244	Target Neighborhood Hits	838	Shared Neighborhood Hits	166
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

MATN4_HUMAN
θ value	0.0193708 (rank : 69)	NC score	0.263326 (rank : 59)
Query Neighborhood Hits	244	Target Neighborhood Hits	287	Shared Neighborhood Hits	146
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

NOTC1_MOUSE
θ value	0.0193708 (rank : 70)	NC score	0.229314 (rank : 111)
Query Neighborhood Hits	244	Target Neighborhood Hits	916	Shared Neighborhood Hits	198
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

SREC2_MOUSE
θ value	0.0193708 (rank : 71)	NC score	0.224179 (rank : 118)
Query Neighborhood Hits	244	Target Neighborhood Hits	605	Shared Neighborhood Hits	184
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

CRDL1_MOUSE
θ value	0.0252991 (rank : 72)	NC score	0.159740 (rank : 208)
Query Neighborhood Hits	244	Target Neighborhood Hits	81	Shared Neighborhood Hits	40
SwissProt Accessions	Q920C1, Q924K0, Q9EPZ9	Gene names	Chrdl1, Ng1, Nrln1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

NAGPA_HUMAN
θ value	0.0252991 (rank : 73)	NC score	0.172837 (rank : 183)
Query Neighborhood Hits	244	Target Neighborhood Hits	282	Shared Neighborhood Hits	120
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NELL2_HUMAN
θ value	0.0252991 (rank : 74)	NC score	0.304472 (rank : 33)
Query Neighborhood Hits	244	Target Neighborhood Hits	449	Shared Neighborhood Hits	184
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

SCUB3_HUMAN
θ value	0.0252991 (rank : 75)	NC score	0.279935 (rank : 41)
Query Neighborhood Hits	244	Target Neighborhood Hits	428	Shared Neighborhood Hits	175
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

FBN1_MOUSE
θ value	0.0330416 (rank : 76)	NC score	0.268401 (rank : 51)
Query Neighborhood Hits	244	Target Neighborhood Hits	563	Shared Neighborhood Hits	201
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FRAS1_HUMAN
θ value	0.0330416 (rank : 77)	NC score	0.239385 (rank : 103)
Query Neighborhood Hits	244	Target Neighborhood Hits	759	Shared Neighborhood Hits	179
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

IGF1R_MOUSE
θ value	0.0330416 (rank : 78)	NC score	0.023178 (rank : 526)
Query Neighborhood Hits	244	Target Neighborhood Hits	973	Shared Neighborhood Hits	84
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

FBLN1_HUMAN
θ value	0.0431538 (rank : 79)	NC score	0.262248 (rank : 63)
Query Neighborhood Hits	244	Target Neighborhood Hits	324	Shared Neighborhood Hits	160
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN1_MOUSE
θ value	0.0431538 (rank : 80)	NC score	0.266846 (rank : 52)
Query Neighborhood Hits	244	Target Neighborhood Hits	329	Shared Neighborhood Hits	162
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

KR107_HUMAN
θ value	0.0431538 (rank : 81)	NC score	0.263355 (rank : 58)
Query Neighborhood Hits	244	Target Neighborhood Hits	330	Shared Neighborhood Hits	144
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

SCUB3_MOUSE
θ value	0.0431538 (rank : 82)	NC score	0.280872 (rank : 39)
Query Neighborhood Hits	244	Target Neighborhood Hits	442	Shared Neighborhood Hits	180
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SLIT1_HUMAN
θ value	0.0431538 (rank : 83)	NC score	0.161453 (rank : 203)
Query Neighborhood Hits	244	Target Neighborhood Hits	700	Shared Neighborhood Hits	175
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

SLIT3_MOUSE
θ value	0.0431538 (rank : 84)	NC score	0.143594 (rank : 234)
Query Neighborhood Hits	244	Target Neighborhood Hits	700	Shared Neighborhood Hits	170
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

FBN1_HUMAN
θ value	0.0563607 (rank : 85)	NC score	0.269757 (rank : 48)
Query Neighborhood Hits	244	Target Neighborhood Hits	557	Shared Neighborhood Hits	204
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

LRP5_MOUSE
θ value	0.0563607 (rank : 86)	NC score	0.188614 (rank : 160)
Query Neighborhood Hits	244	Target Neighborhood Hits	236	Shared Neighborhood Hits	113
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

NAGPA_MOUSE
θ value	0.0563607 (rank : 87)	NC score	0.172437 (rank : 185)
Query Neighborhood Hits	244	Target Neighborhood Hits	308	Shared Neighborhood Hits	137
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

SREC_HUMAN
θ value	0.0563607 (rank : 88)	NC score	0.245728 (rank : 91)
Query Neighborhood Hits	244	Target Neighborhood Hits	645	Shared Neighborhood Hits	189
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

TRBM_MOUSE
θ value	0.0563607 (rank : 89)	NC score	0.283114 (rank : 35)
Query Neighborhood Hits	244	Target Neighborhood Hits	361	Shared Neighborhood Hits	173
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

C1RA_MOUSE
θ value	0.0736092 (rank : 90)	NC score	0.083534 (rank : 356)
Query Neighborhood Hits	244	Target Neighborhood Hits	379	Shared Neighborhood Hits	115
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1RB_MOUSE
θ value	0.0736092 (rank : 91)	NC score	0.082503 (rank : 361)
Query Neighborhood Hits	244	Target Neighborhood Hits	380	Shared Neighborhood Hits	115
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

FA10_MOUSE
θ value	0.0736092 (rank : 92)	NC score	0.093101 (rank : 326)
Query Neighborhood Hits	244	Target Neighborhood Hits	435	Shared Neighborhood Hits	143
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

GAS6_HUMAN
θ value	0.0736092 (rank : 93)	NC score	0.243885 (rank : 96)
Query Neighborhood Hits	244	Target Neighborhood Hits	348	Shared Neighborhood Hits	153
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

HMCN1_HUMAN
θ value	0.0736092 (rank : 94)	NC score	0.170077 (rank : 189)
Query Neighborhood Hits	244	Target Neighborhood Hits	983	Shared Neighborhood Hits	183
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

KR104_HUMAN
θ value	0.0736092 (rank : 95)	NC score	0.278912 (rank : 42)
Query Neighborhood Hits	244	Target Neighborhood Hits	313	Shared Neighborhood Hits	133
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KRA53_HUMAN
θ value	0.0736092 (rank : 96)	NC score	0.240386 (rank : 101)
Query Neighborhood Hits	244	Target Neighborhood Hits	331	Shared Neighborhood Hits	130
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

LRP4_HUMAN
θ value	0.0736092 (rank : 97)	NC score	0.245244 (rank : 92)
Query Neighborhood Hits	244	Target Neighborhood Hits	355	Shared Neighborhood Hits	149
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

CD248_MOUSE
θ value	0.0961366 (rank : 98)	NC score	0.239511 (rank : 102)
Query Neighborhood Hits	244	Target Neighborhood Hits	578	Shared Neighborhood Hits	139
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

TLL2_MOUSE
θ value	0.0961366 (rank : 99)	NC score	0.151280 (rank : 219)
Query Neighborhood Hits	244	Target Neighborhood Hits	240	Shared Neighborhood Hits	122
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TNR16_MOUSE
θ value	0.0961366 (rank : 100)	NC score	0.085080 (rank : 353)
Query Neighborhood Hits	244	Target Neighborhood Hits	178	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

VLDLR_HUMAN
θ value	0.0961366 (rank : 101)	NC score	0.246817 (rank : 90)
Query Neighborhood Hits	244	Target Neighborhood Hits	383	Shared Neighborhood Hits	162
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

LRP4_MOUSE
θ value	0.125558 (rank : 102)	NC score	0.244004 (rank : 95)
Query Neighborhood Hits	244	Target Neighborhood Hits	351	Shared Neighborhood Hits	148
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

TENX_HUMAN
θ value	0.125558 (rank : 103)	NC score	0.162604 (rank : 198)
Query Neighborhood Hits	244	Target Neighborhood Hits	789	Shared Neighborhood Hits	175
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

CRUM1_HUMAN
θ value	0.163984 (rank : 104)	NC score	0.208970 (rank : 138)
Query Neighborhood Hits	244	Target Neighborhood Hits	457	Shared Neighborhood Hits	176
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

FBLN4_HUMAN
θ value	0.163984 (rank : 105)	NC score	0.258249 (rank : 72)
Query Neighborhood Hits	244	Target Neighborhood Hits	278	Shared Neighborhood Hits	147
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FRAS1_MOUSE
θ value	0.163984 (rank : 106)	NC score	0.236298 (rank : 107)
Query Neighborhood Hits	244	Target Neighborhood Hits	747	Shared Neighborhood Hits	175
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

JAG1_HUMAN
θ value	0.163984 (rank : 107)	NC score	0.238172 (rank : 105)
Query Neighborhood Hits	244	Target Neighborhood Hits	514	Shared Neighborhood Hits	189
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

KR106_HUMAN
θ value	0.163984 (rank : 108)	NC score	0.258563 (rank : 71)
Query Neighborhood Hits	244	Target Neighborhood Hits	347	Shared Neighborhood Hits	152
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

NOTC4_HUMAN
θ value	0.163984 (rank : 109)	NC score	0.218703 (rank : 123)
Query Neighborhood Hits	244	Target Neighborhood Hits	905	Shared Neighborhood Hits	200
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

STAB1_HUMAN
θ value	0.163984 (rank : 110)	NC score	0.246970 (rank : 89)
Query Neighborhood Hits	244	Target Neighborhood Hits	546	Shared Neighborhood Hits	190
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

C1QR1_MOUSE
θ value	0.21417 (rank : 111)	NC score	0.259927 (rank : 69)
Query Neighborhood Hits	244	Target Neighborhood Hits	342	Shared Neighborhood Hits	154
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

EGF_MOUSE
θ value	0.21417 (rank : 112)	NC score	0.269547 (rank : 49)
Query Neighborhood Hits	244	Target Neighborhood Hits	358	Shared Neighborhood Hits	161
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

ENPP2_MOUSE
θ value	0.21417 (rank : 113)	NC score	0.033545 (rank : 518)
Query Neighborhood Hits	244	Target Neighborhood Hits	66	Shared Neighborhood Hits	27
SwissProt Accessions	Q9R1E6, Q99LG9	Gene names	Enpp2, Npps2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

FBN2_HUMAN
θ value	0.21417 (rank : 114)	NC score	0.272626 (rank : 46)
Query Neighborhood Hits	244	Target Neighborhood Hits	560	Shared Neighborhood Hits	205
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

GAS6_MOUSE
θ value	0.21417 (rank : 115)	NC score	0.240970 (rank : 99)
Query Neighborhood Hits	244	Target Neighborhood Hits	343	Shared Neighborhood Hits	161
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

NOTC2_HUMAN
θ value	0.21417 (rank : 116)	NC score	0.215035 (rank : 132)
Query Neighborhood Hits	244	Target Neighborhood Hits	1113	Shared Neighborhood Hits	201
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOV_HUMAN
θ value	0.21417 (rank : 117)	NC score	0.123323 (rank : 262)
Query Neighborhood Hits	244	Target Neighborhood Hits	128	Shared Neighborhood Hits	51
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

TGBR3_MOUSE
θ value	0.21417 (rank : 118)	NC score	0.160119 (rank : 207)
Query Neighborhood Hits	244	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	O88393, Q6NS72	Gene names	Tgfbr3
Domain Architecture	No domain graphic available
Description	TGF-beta receptor type III precursor (TGFR-3) (Transforming growth factor beta receptor III) (Betaglycan).

TIE1_MOUSE
θ value	0.21417 (rank : 119)	NC score	0.051477 (rank : 496)
Query Neighborhood Hits	244	Target Neighborhood Hits	1266	Shared Neighborhood Hits	137
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

C1R_HUMAN
θ value	0.279714 (rank : 120)	NC score	0.077108 (rank : 375)
Query Neighborhood Hits	244	Target Neighborhood Hits	364	Shared Neighborhood Hits	112
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

DLL1_MOUSE
θ value	0.279714 (rank : 121)	NC score	0.216420 (rank : 130)
Query Neighborhood Hits	244	Target Neighborhood Hits	456	Shared Neighborhood Hits	185
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

FA10_HUMAN
θ value	0.279714 (rank : 122)	NC score	0.091999 (rank : 329)
Query Neighborhood Hits	244	Target Neighborhood Hits	431	Shared Neighborhood Hits	139
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FBN2_MOUSE
θ value	0.279714 (rank : 123)	NC score	0.273345 (rank : 45)
Query Neighborhood Hits	244	Target Neighborhood Hits	549	Shared Neighborhood Hits	206
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

JAG1_MOUSE
θ value	0.279714 (rank : 124)	NC score	0.234906 (rank : 109)
Query Neighborhood Hits	244	Target Neighborhood Hits	518	Shared Neighborhood Hits	188
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

KRA59_HUMAN
θ value	0.279714 (rank : 125)	NC score	0.213880 (rank : 136)
Query Neighborhood Hits	244	Target Neighborhood Hits	310	Shared Neighborhood Hits	117
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

NOTC2_MOUSE
θ value	0.279714 (rank : 126)	NC score	0.216538 (rank : 129)
Query Neighborhood Hits	244	Target Neighborhood Hits	1069	Shared Neighborhood Hits	201
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

TIE1_HUMAN
θ value	0.279714 (rank : 127)	NC score	0.052694 (rank : 487)
Query Neighborhood Hits	244	Target Neighborhood Hits	1241	Shared Neighborhood Hits	136
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE2_MOUSE
θ value	0.279714 (rank : 128)	NC score	0.049384 (rank : 512)
Query Neighborhood Hits	244	Target Neighborhood Hits	1204	Shared Neighborhood Hits	129
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

TR11B_MOUSE
θ value	0.279714 (rank : 129)	NC score	0.052107 (rank : 490)
Query Neighborhood Hits	244	Target Neighborhood Hits	95	Shared Neighborhood Hits	23
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

BMP1_HUMAN
θ value	0.365318 (rank : 130)	NC score	0.147075 (rank : 226)
Query Neighborhood Hits	244	Target Neighborhood Hits	233	Shared Neighborhood Hits	120
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	0.365318 (rank : 131)	NC score	0.147563 (rank : 224)
Query Neighborhood Hits	244	Target Neighborhood Hits	236	Shared Neighborhood Hits	121
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

ENPP2_HUMAN
θ value	0.365318 (rank : 132)	NC score	0.032264 (rank : 519)
Query Neighborhood Hits	244	Target Neighborhood Hits	61	Shared Neighborhood Hits	27
SwissProt Accessions	Q13822, Q13827, Q15117	Gene names	ENPP2, ATX, PDNP2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) (Autotaxin) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

FBLN4_MOUSE
θ value	0.365318 (rank : 133)	NC score	0.254512 (rank : 75)
Query Neighborhood Hits	244	Target Neighborhood Hits	270	Shared Neighborhood Hits	142
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_HUMAN
θ value	0.365318 (rank : 134)	NC score	0.264501 (rank : 54)
Query Neighborhood Hits	244	Target Neighborhood Hits	329	Shared Neighborhood Hits	168
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBN3_HUMAN
θ value	0.365318 (rank : 135)	NC score	0.268777 (rank : 50)
Query Neighborhood Hits	244	Target Neighborhood Hits	543	Shared Neighborhood Hits	204
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

PROS_HUMAN
θ value	0.365318 (rank : 136)	NC score	0.237459 (rank : 106)
Query Neighborhood Hits	244	Target Neighborhood Hits	340	Shared Neighborhood Hits	158
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

CORIN_MOUSE
θ value	0.47712 (rank : 137)	NC score	0.075824 (rank : 378)
Query Neighborhood Hits	244	Target Neighborhood Hits	451	Shared Neighborhood Hits	119
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

KRA47_HUMAN
θ value	0.47712 (rank : 138)	NC score	0.182820 (rank : 173)
Query Neighborhood Hits	244	Target Neighborhood Hits	204	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

LTB1L_MOUSE
θ value	0.47712 (rank : 139)	NC score	0.247124 (rank : 87)
Query Neighborhood Hits	244	Target Neighborhood Hits	514	Shared Neighborhood Hits	180
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	0.47712 (rank : 140)	NC score	0.247707 (rank : 86)
Query Neighborhood Hits	244	Target Neighborhood Hits	479	Shared Neighborhood Hits	174
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

TNR1A_MOUSE
θ value	0.47712 (rank : 141)	NC score	0.072346 (rank : 392)
Query Neighborhood Hits	244	Target Neighborhood Hits	131	Shared Neighborhood Hits	31
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

FAM5C_HUMAN
θ value	0.62314 (rank : 142)	NC score	0.031177 (rank : 523)
Query Neighborhood Hits	244	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	Q76B58, O95726	Gene names	FAM5C, DBCCR1L, DBCCR1L1
Domain Architecture	No domain graphic available
Description	Protein FAM5C precursor (DBCCR1-like protein 1).

FAM5C_MOUSE
θ value	0.62314 (rank : 143)	NC score	0.031277 (rank : 522)
Query Neighborhood Hits	244	Target Neighborhood Hits	22	Shared Neighborhood Hits	10
SwissProt Accessions	Q499E0, Q8K0R9	Gene names	Fam5c
Domain Architecture	No domain graphic available
Description	Protein FAM5C precursor.

LRP6_MOUSE
θ value	0.62314 (rank : 144)	NC score	0.185008 (rank : 168)
Query Neighborhood Hits	244	Target Neighborhood Hits	232	Shared Neighborhood Hits	114
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

TLL1_HUMAN
θ value	0.62314 (rank : 145)	NC score	0.145222 (rank : 229)
Query Neighborhood Hits	244	Target Neighborhood Hits	236	Shared Neighborhood Hits	119
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL1_MOUSE
θ value	0.62314 (rank : 146)	NC score	0.146605 (rank : 227)
Query Neighborhood Hits	244	Target Neighborhood Hits	237	Shared Neighborhood Hits	121
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL2_HUMAN
θ value	0.62314 (rank : 147)	NC score	0.147400 (rank : 225)
Query Neighborhood Hits	244	Target Neighborhood Hits	241	Shared Neighborhood Hits	122
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

WISP1_MOUSE
θ value	0.62314 (rank : 148)	NC score	0.114377 (rank : 273)
Query Neighborhood Hits	244	Target Neighborhood Hits	123	Shared Neighborhood Hits	42
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

DLL1_HUMAN
θ value	0.813845 (rank : 149)	NC score	0.205162 (rank : 143)
Query Neighborhood Hits	244	Target Neighborhood Hits	455	Shared Neighborhood Hits	180
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

KR102_HUMAN
θ value	0.813845 (rank : 150)	NC score	0.230934 (rank : 110)
Query Neighborhood Hits	244	Target Neighborhood Hits	264	Shared Neighborhood Hits	119
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR109_HUMAN
θ value	0.813845 (rank : 151)	NC score	0.229024 (rank : 112)
Query Neighborhood Hits	244	Target Neighborhood Hits	226	Shared Neighborhood Hits	108
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR10C_HUMAN
θ value	0.813845 (rank : 152)	NC score	0.199803 (rank : 149)
Query Neighborhood Hits	244	Target Neighborhood Hits	219	Shared Neighborhood Hits	100
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KRA94_HUMAN
θ value	0.813845 (rank : 153)	NC score	0.191473 (rank : 154)
Query Neighborhood Hits	244	Target Neighborhood Hits	204	Shared Neighborhood Hits	105
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

FBLN5_MOUSE
θ value	1.06291 (rank : 154)	NC score	0.264167 (rank : 56)
Query Neighborhood Hits	244	Target Neighborhood Hits	317	Shared Neighborhood Hits	160
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FST_HUMAN
θ value	1.06291 (rank : 155)	NC score	0.085190 (rank : 352)
Query Neighborhood Hits	244	Target Neighborhood Hits	129	Shared Neighborhood Hits	48
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

KR10B_HUMAN
θ value	1.06291 (rank : 156)	NC score	0.214763 (rank : 134)
Query Neighborhood Hits	244	Target Neighborhood Hits	269	Shared Neighborhood Hits	121
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

LAMA2_MOUSE
θ value	1.06291 (rank : 157)	NC score	0.110412 (rank : 277)
Query Neighborhood Hits	244	Target Neighborhood Hits	1198	Shared Neighborhood Hits	158
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LRP6_HUMAN
θ value	1.06291 (rank : 158)	NC score	0.184562 (rank : 169)
Query Neighborhood Hits	244	Target Neighborhood Hits	235	Shared Neighborhood Hits	116
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LTB1L_HUMAN
θ value	1.06291 (rank : 159)	NC score	0.248475 (rank : 82)
Query Neighborhood Hits	244	Target Neighborhood Hits	553	Shared Neighborhood Hits	180
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	1.06291 (rank : 160)	NC score	0.248306 (rank : 84)
Query Neighborhood Hits	244	Target Neighborhood Hits	502	Shared Neighborhood Hits	175
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

NOTC3_HUMAN
θ value	1.06291 (rank : 161)	NC score	0.218048 (rank : 124)
Query Neighborhood Hits	244	Target Neighborhood Hits	1062	Shared Neighborhood Hits	197
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

ADA23_MOUSE
θ value	1.38821 (rank : 162)	NC score	0.038891 (rank : 516)
Query Neighborhood Hits	244	Target Neighborhood Hits	245	Shared Neighborhood Hits	102
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

DLL4_HUMAN
θ value	1.38821 (rank : 163)	NC score	0.202635 (rank : 146)
Query Neighborhood Hits	244	Target Neighborhood Hits	435	Shared Neighborhood Hits	172
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

KR101_HUMAN
θ value	1.38821 (rank : 164)	NC score	0.224374 (rank : 117)
Query Neighborhood Hits	244	Target Neighborhood Hits	261	Shared Neighborhood Hits	113
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR414_HUMAN
θ value	1.38821 (rank : 165)	NC score	0.165021 (rank : 194)
Query Neighborhood Hits	244	Target Neighborhood Hits	199	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KRA13_HUMAN
θ value	1.38821 (rank : 166)	NC score	0.189134 (rank : 158)
Query Neighborhood Hits	244	Target Neighborhood Hits	144	Shared Neighborhood Hits	80
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

NOTC4_MOUSE
θ value	1.38821 (rank : 167)	NC score	0.214891 (rank : 133)
Query Neighborhood Hits	244	Target Neighborhood Hits	872	Shared Neighborhood Hits	196
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

SORL_HUMAN
θ value	1.38821 (rank : 168)	NC score	0.181894 (rank : 174)
Query Neighborhood Hits	244	Target Neighborhood Hits	440	Shared Neighborhood Hits	138
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

ADM1B_MOUSE
θ value	1.81305 (rank : 169)	NC score	0.031553 (rank : 520)
Query Neighborhood Hits	244	Target Neighborhood Hits	236	Shared Neighborhood Hits	81
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

CRUM1_MOUSE
θ value	1.81305 (rank : 170)	NC score	0.203268 (rank : 144)
Query Neighborhood Hits	244	Target Neighborhood Hits	444	Shared Neighborhood Hits	174
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

IGF1R_HUMAN
θ value	1.81305 (rank : 171)	NC score	0.021457 (rank : 527)
Query Neighborhood Hits	244	Target Neighborhood Hits	977	Shared Neighborhood Hits	81
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

KR511_HUMAN
θ value	1.81305 (rank : 172)	NC score	0.186671 (rank : 167)
Query Neighborhood Hits	244	Target Neighborhood Hits	231	Shared Neighborhood Hits	90
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA58_HUMAN
θ value	1.81305 (rank : 173)	NC score	0.222848 (rank : 119)
Query Neighborhood Hits	244	Target Neighborhood Hits	324	Shared Neighborhood Hits	126
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

LYAM2_HUMAN
θ value	1.81305 (rank : 174)	NC score	0.091083 (rank : 334)
Query Neighborhood Hits	244	Target Neighborhood Hits	394	Shared Neighborhood Hits	130
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

PROS_MOUSE
θ value	1.81305 (rank : 175)	NC score	0.239204 (rank : 104)
Query Neighborhood Hits	244	Target Neighborhood Hits	330	Shared Neighborhood Hits	151
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

TPA_MOUSE
θ value	1.81305 (rank : 176)	NC score	0.028325 (rank : 525)
Query Neighborhood Hits	244	Target Neighborhood Hits	335	Shared Neighborhood Hits	76
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

WFDC2_HUMAN
θ value	1.81305 (rank : 177)	NC score	0.064485 (rank : 427)
Query Neighborhood Hits	244	Target Neighborhood Hits	73	Shared Neighborhood Hits	33
SwissProt Accessions	Q14508, Q8WXV9, Q8WXW0, Q8WXW1, Q8WXW2, Q96KJ1	Gene names	WFDC2, HE4, WAP5
Domain Architecture
Description	WAP four-disulfide core domain protein 2 precursor (Major epididymis- specific protein E4) (Epididymal secretory protein E4) (Putative protease inhibitor WAP5).

CREL1_MOUSE
θ value	2.36792 (rank : 178)	NC score	0.244280 (rank : 94)
Query Neighborhood Hits	244	Target Neighborhood Hits	524	Shared Neighborhood Hits	152
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

KR410_HUMAN
θ value	2.36792 (rank : 179)	NC score	0.139670 (rank : 243)
Query Neighborhood Hits	244	Target Neighborhood Hits	156	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

LDLR_HUMAN
θ value	2.36792 (rank : 180)	NC score	0.262848 (rank : 61)
Query Neighborhood Hits	244	Target Neighborhood Hits	375	Shared Neighborhood Hits	172
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LTBP3_HUMAN
θ value	2.36792 (rank : 181)	NC score	0.241592 (rank : 97)
Query Neighborhood Hits	244	Target Neighborhood Hits	502	Shared Neighborhood Hits	187
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP3_MOUSE
θ value	2.36792 (rank : 182)	NC score	0.240743 (rank : 100)
Query Neighborhood Hits	244	Target Neighborhood Hits	475	Shared Neighborhood Hits	182
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

MT4_MOUSE
θ value	2.36792 (rank : 183)	NC score	0.133853 (rank : 252)
Query Neighborhood Hits	244	Target Neighborhood Hits	102	Shared Neighborhood Hits	38
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

WISP2_HUMAN
θ value	2.36792 (rank : 184)	NC score	0.103724 (rank : 293)
Query Neighborhood Hits	244	Target Neighborhood Hits	126	Shared Neighborhood Hits	45
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

ALDOB_HUMAN
θ value	3.0926 (rank : 185)	NC score	0.013056 (rank : 530)
Query Neighborhood Hits	244	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	P05062, Q13741, Q13742	Gene names	ALDOB, ALDB
Domain Architecture
Description	Fructose-bisphosphate aldolase B (EC 4.1.2.13) (Liver-type aldolase).

ALDOB_MOUSE
θ value	3.0926 (rank : 186)	NC score	0.013022 (rank : 531)
Query Neighborhood Hits	244	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q91Y97, Q8K034, Q91W73	Gene names	Aldob, Aldo2
Domain Architecture
Description	Fructose-bisphosphate aldolase B (EC 4.1.2.13) (Liver-type aldolase) (Aldolase 2).

ATRN_MOUSE
θ value	3.0926 (rank : 187)	NC score	0.099831 (rank : 308)
Query Neighborhood Hits	244	Target Neighborhood Hits	519	Shared Neighborhood Hits	134
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

CELR3_MOUSE
θ value	3.0926 (rank : 188)	NC score	0.078121 (rank : 372)
Query Neighborhood Hits	244	Target Neighborhood Hits	687	Shared Neighborhood Hits	154
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

CNTP4_HUMAN
θ value	3.0926 (rank : 189)	NC score	0.040845 (rank : 515)
Query Neighborhood Hits	244	Target Neighborhood Hits	187	Shared Neighborhood Hits	59
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

GRN_HUMAN
θ value	3.0926 (rank : 190)	NC score	0.221338 (rank : 121)
Query Neighborhood Hits	244	Target Neighborhood Hits	268	Shared Neighborhood Hits	148
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

KRA93_HUMAN
θ value	3.0926 (rank : 191)	NC score	0.170445 (rank : 188)
Query Neighborhood Hits	244	Target Neighborhood Hits	203	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

MEGF9_MOUSE
θ value	3.0926 (rank : 192)	NC score	0.134426 (rank : 251)
Query Neighborhood Hits	244	Target Neighborhood Hits	896	Shared Neighborhood Hits	135
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

NTNG2_MOUSE
θ value	3.0926 (rank : 193)	NC score	0.088592 (rank : 341)
Query Neighborhood Hits	244	Target Neighborhood Hits	276	Shared Neighborhood Hits	106
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

RSPO4_HUMAN
θ value	3.0926 (rank : 194)	NC score	0.071099 (rank : 395)
Query Neighborhood Hits	244	Target Neighborhood Hits	110	Shared Neighborhood Hits	47
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

TIE2_HUMAN
θ value	3.0926 (rank : 195)	NC score	0.044511 (rank : 513)
Query Neighborhood Hits	244	Target Neighborhood Hits	1192	Shared Neighborhood Hits	129
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TNR8_HUMAN
θ value	3.0926 (rank : 196)	NC score	0.087201 (rank : 349)
Query Neighborhood Hits	244	Target Neighborhood Hits	198	Shared Neighborhood Hits	55
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TNR9_MOUSE
θ value	3.0926 (rank : 197)	NC score	0.070896 (rank : 397)
Query Neighborhood Hits	244	Target Neighborhood Hits	137	Shared Neighborhood Hits	40
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

ASTN_HUMAN
θ value	4.03905 (rank : 198)	NC score	0.076708 (rank : 376)
Query Neighborhood Hits	244	Target Neighborhood Hits	105	Shared Neighborhood Hits	76
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

EDIL3_MOUSE
θ value	4.03905 (rank : 199)	NC score	0.131509 (rank : 254)
Query Neighborhood Hits	244	Target Neighborhood Hits	317	Shared Neighborhood Hits	124
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

FST_MOUSE
θ value	4.03905 (rank : 200)	NC score	0.083021 (rank : 358)
Query Neighborhood Hits	244	Target Neighborhood Hits	146	Shared Neighborhood Hits	64
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

INSR_MOUSE
θ value	4.03905 (rank : 201)	NC score	0.017123 (rank : 529)
Query Neighborhood Hits	244	Target Neighborhood Hits	968	Shared Neighborhood Hits	68
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

JAG2_MOUSE
θ value	4.03905 (rank : 202)	NC score	0.217199 (rank : 127)
Query Neighborhood Hits	244	Target Neighborhood Hits	504	Shared Neighborhood Hits	181
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

LRP8_HUMAN
θ value	4.03905 (rank : 203)	NC score	0.235742 (rank : 108)
Query Neighborhood Hits	244	Target Neighborhood Hits	346	Shared Neighborhood Hits	150
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP8_MOUSE
θ value	4.03905 (rank : 204)	NC score	0.244420 (rank : 93)
Query Neighborhood Hits	244	Target Neighborhood Hits	385	Shared Neighborhood Hits	160
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

NOTC3_MOUSE
θ value	4.03905 (rank : 205)	NC score	0.215052 (rank : 131)
Query Neighborhood Hits	244	Target Neighborhood Hits	975	Shared Neighborhood Hits	197
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

SRPX_MOUSE
θ value	4.03905 (rank : 206)	NC score	0.031416 (rank : 521)
Query Neighborhood Hits	244	Target Neighborhood Hits	75	Shared Neighborhood Hits	21
SwissProt Accessions	Q9R0M3, Q9R0M2	Gene names	Srpx
Domain Architecture	No domain graphic available
Description	Sushi-repeat-containing protein SRPX precursor (DRS protein).

TSP1_HUMAN
θ value	4.03905 (rank : 207)	NC score	0.176823 (rank : 179)
Query Neighborhood Hits	244	Target Neighborhood Hits	389	Shared Neighborhood Hits	147
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_MOUSE
θ value	4.03905 (rank : 208)	NC score	0.173708 (rank : 182)
Query Neighborhood Hits	244	Target Neighborhood Hits	396	Shared Neighborhood Hits	149
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

CELR2_HUMAN
θ value	5.27518 (rank : 209)	NC score	0.081081 (rank : 365)
Query Neighborhood Hits	244	Target Neighborhood Hits	657	Shared Neighborhood Hits	163
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CELR3_HUMAN
θ value	5.27518 (rank : 210)	NC score	0.077570 (rank : 373)
Query Neighborhood Hits	244	Target Neighborhood Hits	680	Shared Neighborhood Hits	150
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

FA9_HUMAN
θ value	5.27518 (rank : 211)	NC score	0.073716 (rank : 384)
Query Neighborhood Hits	244	Target Neighborhood Hits	421	Shared Neighborhood Hits	138
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

INSR_HUMAN
θ value	5.27518 (rank : 212)	NC score	0.017208 (rank : 528)
Query Neighborhood Hits	244	Target Neighborhood Hits	963	Shared Neighborhood Hits	76
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

JAG2_HUMAN
θ value	5.27518 (rank : 213)	NC score	0.224452 (rank : 116)
Query Neighborhood Hits	244	Target Neighborhood Hits	491	Shared Neighborhood Hits	181
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

LAMA5_HUMAN
θ value	5.27518 (rank : 214)	NC score	0.139377 (rank : 245)
Query Neighborhood Hits	244	Target Neighborhood Hits	976	Shared Neighborhood Hits	176
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LCE1A_HUMAN
θ value	5.27518 (rank : 215)	NC score	0.274396 (rank : 44)
Query Neighborhood Hits	244	Target Neighborhood Hits	47	Shared Neighborhood Hits	27
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

NOV_MOUSE
θ value	5.27518 (rank : 216)	NC score	0.095997 (rank : 314)
Query Neighborhood Hits	244	Target Neighborhood Hits	130	Shared Neighborhood Hits	50
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

SORL_MOUSE
θ value	5.27518 (rank : 217)	NC score	0.187068 (rank : 166)
Query Neighborhood Hits	244	Target Neighborhood Hits	439	Shared Neighborhood Hits	142
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

WISP1_HUMAN
θ value	5.27518 (rank : 218)	NC score	0.099972 (rank : 307)
Query Neighborhood Hits	244	Target Neighborhood Hits	121	Shared Neighborhood Hits	42
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

WISP2_MOUSE
θ value	5.27518 (rank : 219)	NC score	0.115066 (rank : 272)
Query Neighborhood Hits	244	Target Neighborhood Hits	129	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

ADA23_HUMAN
θ value	6.88961 (rank : 220)	NC score	0.037538 (rank : 517)
Query Neighborhood Hits	244	Target Neighborhood Hits	235	Shared Neighborhood Hits	93
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

CD97_HUMAN
θ value	6.88961 (rank : 221)	NC score	0.182893 (rank : 172)
Query Neighborhood Hits	244	Target Neighborhood Hits	353	Shared Neighborhood Hits	144
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CORIN_HUMAN
θ value	6.88961 (rank : 222)	NC score	0.075760 (rank : 379)
Query Neighborhood Hits	244	Target Neighborhood Hits	453	Shared Neighborhood Hits	125
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

KR103_HUMAN
θ value	6.88961 (rank : 223)	NC score	0.155768 (rank : 213)
Query Neighborhood Hits	244	Target Neighborhood Hits	212	Shared Neighborhood Hits	100
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

KR105_HUMAN
θ value	6.88961 (rank : 224)	NC score	0.209708 (rank : 137)
Query Neighborhood Hits	244	Target Neighborhood Hits	271	Shared Neighborhood Hits	117
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KRA57_HUMAN
θ value	6.88961 (rank : 225)	NC score	0.184063 (rank : 170)
Query Neighborhood Hits	244	Target Neighborhood Hits	269	Shared Neighborhood Hits	104
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

LDLR_MOUSE
θ value	6.88961 (rank : 226)	NC score	0.250325 (rank : 81)
Query Neighborhood Hits	244	Target Neighborhood Hits	382	Shared Neighborhood Hits	167
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LYAM1_HUMAN
θ value	6.88961 (rank : 227)	NC score	0.062003 (rank : 446)
Query Neighborhood Hits	244	Target Neighborhood Hits	315	Shared Neighborhood Hits	100
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM3_MOUSE
θ value	6.88961 (rank : 228)	NC score	0.122074 (rank : 264)
Query Neighborhood Hits	244	Target Neighborhood Hits	390	Shared Neighborhood Hits	136
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

NFX1_HUMAN
θ value	6.88961 (rank : 229)	NC score	0.129621 (rank : 256)
Query Neighborhood Hits	244	Target Neighborhood Hits	405	Shared Neighborhood Hits	116
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

SRPX_HUMAN
θ value	6.88961 (rank : 230)	NC score	0.030096 (rank : 524)
Query Neighborhood Hits	244	Target Neighborhood Hits	69	Shared Neighborhood Hits	18
SwissProt Accessions	P78539, Q99652, Q99913	Gene names	SRPX, ETX1
Domain Architecture
Description	Sushi repeat-containing protein SRPX precursor.

TINAL_HUMAN
θ value	6.88961 (rank : 231)	NC score	0.056506 (rank : 474)
Query Neighborhood Hits	244	Target Neighborhood Hits	50	Shared Neighborhood Hits	19
SwissProt Accessions	Q9GZM7, Q8TEJ9, Q8WZ23, Q96GZ4, Q96JW3	Gene names	TINAGL1, GIS5, LCN7, OLRG2, TINAGL
Domain Architecture	No domain graphic available
Description	Tubulointerstitial nephritis antigen-like precursor (Tubulointerstitial nephritis antigen-related protein) (TIN Ag-related protein) (TIN-Ag-RP) (Glucocorticoid-inducible protein 5) (Oxidized LDL-responsive gene 2 protein) (OLRG-2).

ZNFX1_HUMAN
θ value	6.88961 (rank : 232)	NC score	0.100473 (rank : 304)
Query Neighborhood Hits	244	Target Neighborhood Hits	308	Shared Neighborhood Hits	82
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ZNFX1_MOUSE
θ value	6.88961 (rank : 233)	NC score	0.096813 (rank : 310)
Query Neighborhood Hits	244	Target Neighborhood Hits	407	Shared Neighborhood Hits	80
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ADAM8_HUMAN
θ value	8.99809 (rank : 234)	NC score	0.041629 (rank : 514)
Query Neighborhood Hits	244	Target Neighborhood Hits	327	Shared Neighborhood Hits	110
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

EMR1_MOUSE
θ value	8.99809 (rank : 235)	NC score	0.182969 (rank : 171)
Query Neighborhood Hits	244	Target Neighborhood Hits	349	Shared Neighborhood Hits	141
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

ERR3_HUMAN
θ value	8.99809 (rank : 236)	NC score	0.001879 (rank : 533)
Query Neighborhood Hits	244	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	P62508, O75454, O96021, Q68DA0, Q6P274, Q6PK28, Q6TS38, Q9R1F3, Q9UNJ4	Gene names	ESRRG, ERR3, ERRG2, KIAA0832, NR3B3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (ERR gamma-2).

ERR3_MOUSE
θ value	8.99809 (rank : 237)	NC score	0.001879 (rank : 534)
Query Neighborhood Hits	244	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	P62509, O75454, O96021, Q8CHC9, Q9R1F3	Gene names	Esrrg, Err3, Kiaa0832, Nr3b3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3).

KR108_HUMAN
θ value	8.99809 (rank : 238)	NC score	0.198949 (rank : 150)
Query Neighborhood Hits	244	Target Neighborhood Hits	226	Shared Neighborhood Hits	104
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KRA11_HUMAN
θ value	8.99809 (rank : 239)	NC score	0.143796 (rank : 233)
Query Neighborhood Hits	244	Target Neighborhood Hits	155	Shared Neighborhood Hits	80
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

KRA54_HUMAN
θ value	8.99809 (rank : 240)	NC score	0.162921 (rank : 197)
Query Neighborhood Hits	244	Target Neighborhood Hits	270	Shared Neighborhood Hits	98
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

MTP18_HUMAN
θ value	8.99809 (rank : 241)	NC score	0.009867 (rank : 532)
Query Neighborhood Hits	244	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UDX5, Q9H3K1, Q9P0N6	Gene names	MTP18
Domain Architecture	No domain graphic available
Description	Mitochondrial 18 kDa protein (MTP18).

PROC_MOUSE
θ value	8.99809 (rank : 242)	NC score	0.078487 (rank : 371)
Query Neighborhood Hits	244	Target Neighborhood Hits	426	Shared Neighborhood Hits	142
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

SLIT2_HUMAN
θ value	8.99809 (rank : 243)	NC score	0.142670 (rank : 237)
Query Neighborhood Hits	244	Target Neighborhood Hits	708	Shared Neighborhood Hits	179
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

ST14_MOUSE
θ value	8.99809 (rank : 244)	NC score	0.084991 (rank : 354)
Query Neighborhood Hits	244	Target Neighborhood Hits	419	Shared Neighborhood Hits	125
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

ADA17_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.060256 (rank : 458)
Query Neighborhood Hits	244	Target Neighborhood Hits	223	Shared Neighborhood Hits	95
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ASTN_MOUSE
θ value	θ > 10 (rank : 246)	NC score	0.065251 (rank : 425)
Query Neighborhood Hits	244	Target Neighborhood Hits	98	Shared Neighborhood Hits	72
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

ATRN_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.094615 (rank : 319)
Query Neighborhood Hits	244	Target Neighborhood Hits	525	Shared Neighborhood Hits	134
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

C163A_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.050673 (rank : 503)
Query Neighborhood Hits	244	Target Neighborhood Hits	54	Shared Neighborhood Hits	11
SwissProt Accessions	Q86VB7, Q07898, Q07899, Q07900, Q07901, Q2VLH7	Gene names	CD163, M130
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M130 precursor (CD163 antigen) (Hemoglobin scavenger receptor) [Contains: Soluble CD163 (sCD163)].

C163B_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.050289 (rank : 506)
Query Neighborhood Hits	244	Target Neighborhood Hits	64	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NR16, Q6UWC2	Gene names	CD163L1, CD163B, M160
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M160 precursor (CD163 antigen-like 1) (CD163b antigen).

C1QR1_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.247985 (rank : 85)
Query Neighborhood Hits	244	Target Neighborhood Hits	493	Shared Neighborhood Hits	163
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1S_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.059618 (rank : 460)
Query Neighborhood Hits	244	Target Neighborhood Hits	359	Shared Neighborhood Hits	109
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

CD320_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.096760 (rank : 311)
Query Neighborhood Hits	244	Target Neighborhood Hits	103	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

CD97_MOUSE
θ value	θ > 10 (rank : 253)	NC score	0.161208 (rank : 205)
Query Neighborhood Hits	244	Target Neighborhood Hits	295	Shared Neighborhood Hits	125
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CELR1_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.069851 (rank : 403)
Query Neighborhood Hits	244	Target Neighborhood Hits	613	Shared Neighborhood Hits	144
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CELR1_MOUSE
θ value	θ > 10 (rank : 255)	NC score	0.070562 (rank : 398)
Query Neighborhood Hits	244	Target Neighborhood Hits	617	Shared Neighborhood Hits	145
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

CELR2_MOUSE
θ value	θ > 10 (rank : 256)	NC score	0.068382 (rank : 410)
Query Neighborhood Hits	244	Target Neighborhood Hits	584	Shared Neighborhood Hits	141
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

CER1_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.060809 (rank : 454)
Query Neighborhood Hits	244	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	O95813, Q6ISJ1, Q6ISJ6, Q6ISQ2, Q6ISS1	Gene names	CER1
Domain Architecture	No domain graphic available
Description	Cerberus precursor (Cerberus-related protein).

CFC1_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.072159 (rank : 393)
Query Neighborhood Hits	244	Target Neighborhood Hits	148	Shared Neighborhood Hits	66
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CFC1_MOUSE
θ value	θ > 10 (rank : 259)	NC score	0.052729 (rank : 486)
Query Neighborhood Hits	244	Target Neighborhood Hits	125	Shared Neighborhood Hits	57
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CHRD_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.125433 (rank : 259)
Query Neighborhood Hits	244	Target Neighborhood Hits	102	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

CHRD_MOUSE
θ value	θ > 10 (rank : 261)	NC score	0.117058 (rank : 268)
Query Neighborhood Hits	244	Target Neighborhood Hits	102	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

CK024_MOUSE
θ value	θ > 10 (rank : 262)	NC score	0.089459 (rank : 337)
Query Neighborhood Hits	244	Target Neighborhood Hits	307	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

CLC14_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.086092 (rank : 351)
Query Neighborhood Hits	244	Target Neighborhood Hits	143	Shared Neighborhood Hits	89
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

CLC14_MOUSE
θ value	θ > 10 (rank : 264)	NC score	0.088670 (rank : 340)
Query Neighborhood Hits	244	Target Neighborhood Hits	120	Shared Neighborhood Hits	85
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

CO6A3_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.063653 (rank : 433)
Query Neighborhood Hits	244	Target Neighborhood Hits	317	Shared Neighborhood Hits	12
SwissProt Accessions	P12111, Q16501	Gene names	COL6A3
Domain Architecture
Description	Collagen alpha-3(VI) chain precursor.

CO6_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.056603 (rank : 473)
Query Neighborhood Hits	244	Target Neighborhood Hits	331	Shared Neighborhood Hits	77
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CO7_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.051311 (rank : 498)
Query Neighborhood Hits	244	Target Neighborhood Hits	278	Shared Neighborhood Hits	78
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO8B_MOUSE
θ value	θ > 10 (rank : 268)	NC score	0.051940 (rank : 494)
Query Neighborhood Hits	244	Target Neighborhood Hits	224	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO9_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.051268 (rank : 499)
Query Neighborhood Hits	244	Target Neighborhood Hits	147	Shared Neighborhood Hits	52
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

COCH_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.072729 (rank : 388)
Query Neighborhood Hits	244	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	O43405	Gene names	COCH, COCH5B2
Domain Architecture
Description	Cochlin precursor (COCH-5B2).

COCH_MOUSE
θ value	θ > 10 (rank : 271)	NC score	0.072534 (rank : 391)
Query Neighborhood Hits	244	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	Q62507, Q3TAF5, Q9QWK6	Gene names	Coch
Domain Architecture
Description	Cochlin precursor (COCH-5B2).

COKA1_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.050073 (rank : 510)
Query Neighborhood Hits	244	Target Neighborhood Hits	403	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

COMP_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.165286 (rank : 193)
Query Neighborhood Hits	244	Target Neighborhood Hits	258	Shared Neighborhood Hits	126
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

COMP_MOUSE
θ value	θ > 10 (rank : 274)	NC score	0.174333 (rank : 180)
Query Neighborhood Hits	244	Target Neighborhood Hits	290	Shared Neighborhood Hits	132
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CRAC1_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.109346 (rank : 279)
Query Neighborhood Hits	244	Target Neighborhood Hits	111	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRAC1_MOUSE
θ value	θ > 10 (rank : 276)	NC score	0.111155 (rank : 275)
Query Neighborhood Hits	244	Target Neighborhood Hits	112	Shared Neighborhood Hits	77
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRDL1_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.115278 (rank : 271)
Query Neighborhood Hits	244	Target Neighborhood Hits	75	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BU40, Q9Y3H7	Gene names	CHRDL1, NRLN1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CRDL2_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.139597 (rank : 244)
Query Neighborhood Hits	244	Target Neighborhood Hits	99	Shared Neighborhood Hits	38
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

CRDL2_MOUSE
θ value	θ > 10 (rank : 279)	NC score	0.143036 (rank : 235)
Query Neighborhood Hits	244	Target Neighborhood Hits	81	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

CREL1_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.241043 (rank : 98)
Query Neighborhood Hits	244	Target Neighborhood Hits	441	Shared Neighborhood Hits	146
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CRIM1_HUMAN
θ value	θ > 10 (rank : 281)	NC score	0.280469 (rank : 40)
Query Neighborhood Hits	244	Target Neighborhood Hits	362	Shared Neighborhood Hits	136
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

CRUM2_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.207036 (rank : 139)
Query Neighborhood Hits	244	Target Neighborhood Hits	453	Shared Neighborhood Hits	175
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

CS1A_MOUSE
θ value	θ > 10 (rank : 283)	NC score	0.061440 (rank : 450)
Query Neighborhood Hits	244	Target Neighborhood Hits	360	Shared Neighborhood Hits	109
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CS1B_MOUSE
θ value	θ > 10 (rank : 284)	NC score	0.061261 (rank : 452)
Query Neighborhood Hits	244	Target Neighborhood Hits	361	Shared Neighborhood Hits	109
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

CSMD1_HUMAN
θ value	θ > 10 (rank : 285)	NC score	0.057000 (rank : 470)
Query Neighborhood Hits	244	Target Neighborhood Hits	176	Shared Neighborhood Hits	39
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD1_MOUSE
θ value	θ > 10 (rank : 286)	NC score	0.057609 (rank : 468)
Query Neighborhood Hits	244	Target Neighborhood Hits	193	Shared Neighborhood Hits	47
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD2_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.054042 (rank : 482)
Query Neighborhood Hits	244	Target Neighborhood Hits	188	Shared Neighborhood Hits	40
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CSMD3_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.054157 (rank : 480)
Query Neighborhood Hits	244	Target Neighborhood Hits	199	Shared Neighborhood Hits	42
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CSPG2_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.120336 (rank : 265)
Query Neighborhood Hits	244	Target Neighborhood Hits	681	Shared Neighborhood Hits	122
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CSPG2_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.123648 (rank : 261)
Query Neighborhood Hits	244	Target Neighborhood Hits	711	Shared Neighborhood Hits	126
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CSPG3_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.105642 (rank : 287)
Query Neighborhood Hits	244	Target Neighborhood Hits	676	Shared Neighborhood Hits	118
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CSPG3_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.102293 (rank : 297)
Query Neighborhood Hits	244	Target Neighborhood Hits	657	Shared Neighborhood Hits	120
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CT127_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.052007 (rank : 493)
Query Neighborhood Hits	244	Target Neighborhood Hits	67	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

CTGF_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.089171 (rank : 338)
Query Neighborhood Hits	244	Target Neighborhood Hits	128	Shared Neighborhood Hits	49
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

CTGF_MOUSE
θ value	θ > 10 (rank : 295)	NC score	0.087908 (rank : 347)
Query Neighborhood Hits	244	Target Neighborhood Hits	124	Shared Neighborhood Hits	47
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

CUBN_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.219664 (rank : 122)
Query Neighborhood Hits	244	Target Neighborhood Hits	482	Shared Neighborhood Hits	170
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CUBN_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.221886 (rank : 120)
Query Neighborhood Hits	244	Target Neighborhood Hits	477	Shared Neighborhood Hits	173
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CYR61_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.086880 (rank : 350)
Query Neighborhood Hits	244	Target Neighborhood Hits	159	Shared Neighborhood Hits	53
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

CYR61_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.089784 (rank : 336)
Query Neighborhood Hits	244	Target Neighborhood Hits	156	Shared Neighborhood Hits	52
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

DLK_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.195091 (rank : 152)
Query Neighborhood Hits	244	Target Neighborhood Hits	401	Shared Neighborhood Hits	162
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLK_MOUSE
θ value	θ > 10 (rank : 301)	NC score	0.193334 (rank : 153)
Query Neighborhood Hits	244	Target Neighborhood Hits	374	Shared Neighborhood Hits	158
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

DLL3_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.188395 (rank : 161)
Query Neighborhood Hits	244	Target Neighborhood Hits	419	Shared Neighborhood Hits	157
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DLL3_MOUSE
θ value	θ > 10 (rank : 303)	NC score	0.188279 (rank : 162)
Query Neighborhood Hits	244	Target Neighborhood Hits	399	Shared Neighborhood Hits	149
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

DLL4_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.200430 (rank : 148)
Query Neighborhood Hits	244	Target Neighborhood Hits	440	Shared Neighborhood Hits	172
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DNER_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.205377 (rank : 142)
Query Neighborhood Hits	244	Target Neighborhood Hits	460	Shared Neighborhood Hits	167
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DNER_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.200792 (rank : 147)
Query Neighborhood Hits	244	Target Neighborhood Hits	413	Shared Neighborhood Hits	160
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

EDIL3_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.126991 (rank : 258)
Query Neighborhood Hits	244	Target Neighborhood Hits	292	Shared Neighborhood Hits	124
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EGFL7_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.202952 (rank : 145)
Query Neighborhood Hits	244	Target Neighborhood Hits	325	Shared Neighborhood Hits	151
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL7_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.171091 (rank : 187)
Query Neighborhood Hits	244	Target Neighborhood Hits	287	Shared Neighborhood Hits	142
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EGFL8_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.169032 (rank : 190)
Query Neighborhood Hits	244	Target Neighborhood Hits	270	Shared Neighborhood Hits	137
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL8_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.166451 (rank : 192)
Query Neighborhood Hits	244	Target Neighborhood Hits	266	Shared Neighborhood Hits	135
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EGFL9_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.187168 (rank : 165)
Query Neighborhood Hits	244	Target Neighborhood Hits	365	Shared Neighborhood Hits	155
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
θ value	θ > 10 (rank : 313)	NC score	0.189751 (rank : 156)
Query Neighborhood Hits	244	Target Neighborhood Hits	379	Shared Neighborhood Hits	156
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

ELTD1_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.106447 (rank : 284)
Query Neighborhood Hits	244	Target Neighborhood Hits	269	Shared Neighborhood Hits	115
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

ELTD1_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.158878 (rank : 210)
Query Neighborhood Hits	244	Target Neighborhood Hits	288	Shared Neighborhood Hits	122
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

EMR1_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.195942 (rank : 151)
Query Neighborhood Hits	244	Target Neighborhood Hits	382	Shared Neighborhood Hits	151
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EMR2_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.181405 (rank : 175)
Query Neighborhood Hits	244	Target Neighborhood Hits	345	Shared Neighborhood Hits	140
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

EMR3_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.090574 (rank : 335)
Query Neighborhood Hits	244	Target Neighborhood Hits	245	Shared Neighborhood Hits	104
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

EMR4_MOUSE
θ value	θ > 10 (rank : 319)	NC score	0.053928 (rank : 483)
Query Neighborhood Hits	244	Target Neighborhood Hits	191	Shared Neighborhood Hits	79
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

ENTK_MOUSE
θ value	θ > 10 (rank : 320)	NC score	0.050749 (rank : 502)
Query Neighborhood Hits	244	Target Neighborhood Hits	338	Shared Neighborhood Hits	53
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

ESM1_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.057672 (rank : 467)
Query Neighborhood Hits	244	Target Neighborhood Hits	110	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

ESM1_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.052009 (rank : 492)
Query Neighborhood Hits	244	Target Neighborhood Hits	107	Shared Neighborhood Hits	44
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

FA7_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.064480 (rank : 428)
Query Neighborhood Hits	244	Target Neighborhood Hits	404	Shared Neighborhood Hits	132
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

FA7_MOUSE
θ value	θ > 10 (rank : 324)	NC score	0.051850 (rank : 495)
Query Neighborhood Hits	244	Target Neighborhood Hits	374	Shared Neighborhood Hits	119
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

FATH_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.093171 (rank : 325)
Query Neighborhood Hits	244	Target Neighborhood Hits	570	Shared Neighborhood Hits	150
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

FSTL1_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.066879 (rank : 418)
Query Neighborhood Hits	244	Target Neighborhood Hits	68	Shared Neighborhood Hits	14
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

FSTL1_MOUSE
θ value	θ > 10 (rank : 327)	NC score	0.064357 (rank : 429)
Query Neighborhood Hits	244	Target Neighborhood Hits	74	Shared Neighborhood Hits	13
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

FSTL3_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.064306 (rank : 431)
Query Neighborhood Hits	244	Target Neighborhood Hits	162	Shared Neighborhood Hits	66
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL3_MOUSE
θ value	θ > 10 (rank : 329)	NC score	0.065552 (rank : 424)
Query Neighborhood Hits	244	Target Neighborhood Hits	152	Shared Neighborhood Hits	70
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

GP112_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.075619 (rank : 380)
Query Neighborhood Hits	244	Target Neighborhood Hits	441	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

GRN_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.217784 (rank : 125)
Query Neighborhood Hits	244	Target Neighborhood Hits	248	Shared Neighborhood Hits	142
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

HABP2_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.069207 (rank : 405)
Query Neighborhood Hits	244	Target Neighborhood Hits	431	Shared Neighborhood Hits	116
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HABP2_MOUSE
θ value	θ > 10 (rank : 333)	NC score	0.067474 (rank : 415)
Query Neighborhood Hits	244	Target Neighborhood Hits	445	Shared Neighborhood Hits	121
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HG2A_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.063880 (rank : 432)
Query Neighborhood Hits	244	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	P04233, Q14597, Q29832, Q5U0J8, Q8WLP6	Gene names	CD74, DHLAG
Domain Architecture	No domain graphic available
Description	HLA class II histocompatibility antigen gamma chain (HLA-DR antigens- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (p33) (CD74 antigen).

HG2A_MOUSE
θ value	θ > 10 (rank : 335)	NC score	0.068044 (rank : 411)
Query Neighborhood Hits	244	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	P04441, O19452	Gene names	Cd74, Ii
Domain Architecture
Description	H-2 class II histocompatibility antigen gamma chain (MHC class II- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD74 antigen).

HGFA_MOUSE
θ value	θ > 10 (rank : 336)	NC score	0.054216 (rank : 479)
Query Neighborhood Hits	244	Target Neighborhood Hits	419	Shared Neighborhood Hits	112
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HHIP_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.088516 (rank : 344)
Query Neighborhood Hits	244	Target Neighborhood Hits	249	Shared Neighborhood Hits	103
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HHIP_MOUSE
θ value	θ > 10 (rank : 338)	NC score	0.079745 (rank : 369)
Query Neighborhood Hits	244	Target Neighborhood Hits	219	Shared Neighborhood Hits	84
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

IDD_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.053768 (rank : 485)
Query Neighborhood Hits	244	Target Neighborhood Hits	127	Shared Neighborhood Hits	33
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

ITB1_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.088153 (rank : 345)
Query Neighborhood Hits	244	Target Neighborhood Hits	298	Shared Neighborhood Hits	118
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB1_MOUSE
θ value	θ > 10 (rank : 341)	NC score	0.081971 (rank : 363)
Query Neighborhood Hits	244	Target Neighborhood Hits	283	Shared Neighborhood Hits	114
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB2_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.083373 (rank : 357)
Query Neighborhood Hits	244	Target Neighborhood Hits	282	Shared Neighborhood Hits	123
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB2_MOUSE
θ value	θ > 10 (rank : 343)	NC score	0.096533 (rank : 312)
Query Neighborhood Hits	244	Target Neighborhood Hits	326	Shared Neighborhood Hits	138
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB3_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.097476 (rank : 309)
Query Neighborhood Hits	244	Target Neighborhood Hits	325	Shared Neighborhood Hits	141
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB3_MOUSE
θ value	θ > 10 (rank : 345)	NC score	0.096263 (rank : 313)
Query Neighborhood Hits	244	Target Neighborhood Hits	319	Shared Neighborhood Hits	133
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB4_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.079605 (rank : 370)
Query Neighborhood Hits	244	Target Neighborhood Hits	458	Shared Neighborhood Hits	116
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

ITB5_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.094624 (rank : 318)
Query Neighborhood Hits	244	Target Neighborhood Hits	310	Shared Neighborhood Hits	135
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB5_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.104260 (rank : 291)
Query Neighborhood Hits	244	Target Neighborhood Hits	329	Shared Neighborhood Hits	138
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB6_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.093717 (rank : 323)
Query Neighborhood Hits	244	Target Neighborhood Hits	318	Shared Neighborhood Hits	126
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB6_MOUSE
θ value	θ > 10 (rank : 350)	NC score	0.104727 (rank : 290)
Query Neighborhood Hits	244	Target Neighborhood Hits	341	Shared Neighborhood Hits	135
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB7_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.088860 (rank : 339)
Query Neighborhood Hits	244	Target Neighborhood Hits	290	Shared Neighborhood Hits	125
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

ITB7_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.084583 (rank : 355)
Query Neighborhood Hits	244	Target Neighborhood Hits	277	Shared Neighborhood Hits	115
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

ITB8_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.072990 (rank : 387)
Query Neighborhood Hits	244	Target Neighborhood Hits	280	Shared Neighborhood Hits	116
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

KR10A_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.163326 (rank : 196)
Query Neighborhood Hits	244	Target Neighborhood Hits	232	Shared Neighborhood Hits	109
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

KR111_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.058552 (rank : 463)
Query Neighborhood Hits	244	Target Neighborhood Hits	90	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IUC1	Gene names	KRTAP11-1, KAP11.1, KRTAP11.1
Domain Architecture
Description	Keratin-associated protein 11-1 (High sulfur keratin-associated protein 11.1).

KR122_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.055823 (rank : 476)
Query Neighborhood Hits	244	Target Neighborhood Hits	97	Shared Neighborhood Hits	43
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

KR124_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.053876 (rank : 484)
Query Neighborhood Hits	244	Target Neighborhood Hits	124	Shared Neighborhood Hits	51
SwissProt Accessions	P60329	Gene names	KRTAP12-4, KAP12.4, KRTAP12.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-4 (Keratin-associated protein 12.4) (High sulfur keratin-associated protein 12.4).

KR171_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.145097 (rank : 231)
Query Neighborhood Hits	244	Target Neighborhood Hits	144	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KR412_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.161729 (rank : 202)
Query Neighborhood Hits	244	Target Neighborhood Hits	178	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR413_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.101616 (rank : 301)
Query Neighborhood Hits	244	Target Neighborhood Hits	112	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

KR510_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.131824 (rank : 253)
Query Neighborhood Hits	244	Target Neighborhood Hits	217	Shared Neighborhood Hits	76
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KRA15_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.145062 (rank : 232)
Query Neighborhood Hits	244	Target Neighborhood Hits	126	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KRA24_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.080454 (rank : 366)
Query Neighborhood Hits	244	Target Neighborhood Hits	192	Shared Neighborhood Hits	73
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

KRA42_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.107484 (rank : 281)
Query Neighborhood Hits	244	Target Neighborhood Hits	149	Shared Neighborhood Hits	74
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

KRA44_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.142998 (rank : 236)
Query Neighborhood Hits	244	Target Neighborhood Hits	162	Shared Neighborhood Hits	80
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KRA45_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.161241 (rank : 204)
Query Neighborhood Hits	244	Target Neighborhood Hits	194	Shared Neighborhood Hits	95
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

KRA51_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.153911 (rank : 216)
Query Neighborhood Hits	244	Target Neighborhood Hits	288	Shared Neighborhood Hits	105
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA52_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.157433 (rank : 212)
Query Neighborhood Hits	244	Target Neighborhood Hits	236	Shared Neighborhood Hits	86
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KRA55_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.159608 (rank : 209)
Query Neighborhood Hits	244	Target Neighborhood Hits	257	Shared Neighborhood Hits	97
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA56_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.164356 (rank : 195)
Query Neighborhood Hits	244	Target Neighborhood Hits	207	Shared Neighborhood Hits	80
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA92_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.174072 (rank : 181)
Query Neighborhood Hits	244	Target Neighborhood Hits	198	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA98_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.167852 (rank : 191)
Query Neighborhood Hits	244	Target Neighborhood Hits	185	Shared Neighborhood Hits	89
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA99_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.142467 (rank : 238)
Query Neighborhood Hits	244	Target Neighborhood Hits	173	Shared Neighborhood Hits	89
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

LAMA1_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.128013 (rank : 257)
Query Neighborhood Hits	244	Target Neighborhood Hits	804	Shared Neighborhood Hits	159
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA2_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.113398 (rank : 274)
Query Neighborhood Hits	244	Target Neighborhood Hits	1092	Shared Neighborhood Hits	159
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA3_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.082629 (rank : 359)
Query Neighborhood Hits	244	Target Neighborhood Hits	760	Shared Neighborhood Hits	122
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

LAMA3_MOUSE
θ value	θ > 10 (rank : 377)	NC score	0.101648 (rank : 300)
Query Neighborhood Hits	244	Target Neighborhood Hits	859	Shared Neighborhood Hits	154
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LAMA4_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.067559 (rank : 414)
Query Neighborhood Hits	244	Target Neighborhood Hits	708	Shared Neighborhood Hits	103
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA4_MOUSE
θ value	θ > 10 (rank : 379)	NC score	0.073495 (rank : 385)
Query Neighborhood Hits	244	Target Neighborhood Hits	584	Shared Neighborhood Hits	106
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA5_MOUSE
θ value	θ > 10 (rank : 380)	NC score	0.137564 (rank : 248)
Query Neighborhood Hits	244	Target Neighborhood Hits	828	Shared Neighborhood Hits	174
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB1_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.100292 (rank : 305)
Query Neighborhood Hits	244	Target Neighborhood Hits	1018	Shared Neighborhood Hits	156
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB1_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.106863 (rank : 282)
Query Neighborhood Hits	244	Target Neighborhood Hits	919	Shared Neighborhood Hits	148
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB2_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.117660 (rank : 267)
Query Neighborhood Hits	244	Target Neighborhood Hits	692	Shared Neighborhood Hits	149
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB2_MOUSE
θ value	θ > 10 (rank : 384)	NC score	0.115718 (rank : 269)
Query Neighborhood Hits	244	Target Neighborhood Hits	722	Shared Neighborhood Hits	152
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMB3_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.076164 (rank : 377)
Query Neighborhood Hits	244	Target Neighborhood Hits	461	Shared Neighborhood Hits	103
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMB3_MOUSE
θ value	θ > 10 (rank : 386)	NC score	0.091536 (rank : 330)
Query Neighborhood Hits	244	Target Neighborhood Hits	444	Shared Neighborhood Hits	125
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LAMC1_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.106205 (rank : 285)
Query Neighborhood Hits	244	Target Neighborhood Hits	922	Shared Neighborhood Hits	148
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC1_MOUSE
θ value	θ > 10 (rank : 388)	NC score	0.108733 (rank : 280)
Query Neighborhood Hits	244	Target Neighborhood Hits	856	Shared Neighborhood Hits	146
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC2_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.095740 (rank : 315)
Query Neighborhood Hits	244	Target Neighborhood Hits	715	Shared Neighborhood Hits	135
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LAMC2_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.105184 (rank : 289)
Query Neighborhood Hits	244	Target Neighborhood Hits	614	Shared Neighborhood Hits	145
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LAMC3_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.122099 (rank : 263)
Query Neighborhood Hits	244	Target Neighborhood Hits	588	Shared Neighborhood Hits	158
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC3_MOUSE
θ value	θ > 10 (rank : 392)	NC score	0.115654 (rank : 270)
Query Neighborhood Hits	244	Target Neighborhood Hits	624	Shared Neighborhood Hits	151
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LCE1B_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.140436 (rank : 242)
Query Neighborhood Hits	244	Target Neighborhood Hits	58	Shared Neighborhood Hits	32
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.179510 (rank : 176)
Query Neighborhood Hits	244	Target Neighborhood Hits	65	Shared Neighborhood Hits	33
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1D_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.095319 (rank : 317)
Query Neighborhood Hits	244	Target Neighborhood Hits	44	Shared Neighborhood Hits	24
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE1E_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.217045 (rank : 128)
Query Neighborhood Hits	244	Target Neighborhood Hits	53	Shared Neighborhood Hits	29
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LCE1F_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.226348 (rank : 114)
Query Neighborhood Hits	244	Target Neighborhood Hits	48	Shared Neighborhood Hits	25
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LCE2A_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.130407 (rank : 255)
Query Neighborhood Hits	244	Target Neighborhood Hits	50	Shared Neighborhood Hits	21
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

LCE2B_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.102056 (rank : 299)
Query Neighborhood Hits	244	Target Neighborhood Hits	50	Shared Neighborhood Hits	16
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

LCE2C_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.119304 (rank : 266)
Query Neighborhood Hits	244	Target Neighborhood Hits	53	Shared Neighborhood Hits	22
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LCE2D_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.105710 (rank : 286)
Query Neighborhood Hits	244	Target Neighborhood Hits	50	Shared Neighborhood Hits	19
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

LCE3A_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.187338 (rank : 163)
Query Neighborhood Hits	244	Target Neighborhood Hits	29	Shared Neighborhood Hits	19
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

LCE3B_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.152531 (rank : 217)
Query Neighborhood Hits	244	Target Neighborhood Hits	47	Shared Neighborhood Hits	27
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

LCE3C_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.069151 (rank : 406)
Query Neighborhood Hits	244	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T5A8	Gene names	LCE3C, LEP15, SPRL3A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A).

LCE4A_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.092531 (rank : 328)
Query Neighborhood Hits	244	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

LCE5A_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.135560 (rank : 250)
Query Neighborhood Hits	244	Target Neighborhood Hits	43	Shared Neighborhood Hits	15
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

LEUK_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.067242 (rank : 416)
Query Neighborhood Hits	244	Target Neighborhood Hits	213	Shared Neighborhood Hits	7
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

LR37A_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.052096 (rank : 491)
Query Neighborhood Hits	244	Target Neighborhood Hits	720	Shared Neighborhood Hits	12
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

LRP10_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.067096 (rank : 417)
Query Neighborhood Hits	244	Target Neighborhood Hits	197	Shared Neighborhood Hits	46
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP10_MOUSE
θ value	θ > 10 (rank : 410)	NC score	0.074532 (rank : 382)
Query Neighborhood Hits	244	Target Neighborhood Hits	169	Shared Neighborhood Hits	50
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP12_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.102995 (rank : 295)
Query Neighborhood Hits	244	Target Neighborhood Hits	205	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
θ value	θ > 10 (rank : 412)	NC score	0.100702 (rank : 303)
Query Neighborhood Hits	244	Target Neighborhood Hits	180	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP3_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.106626 (rank : 283)
Query Neighborhood Hits	244	Target Neighborhood Hits	280	Shared Neighborhood Hits	82
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

LTBP4_MOUSE
θ value	θ > 10 (rank : 414)	NC score	0.248432 (rank : 83)
Query Neighborhood Hits	244	Target Neighborhood Hits	607	Shared Neighborhood Hits	181
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

LYAM1_MOUSE
θ value	θ > 10 (rank : 415)	NC score	0.063419 (rank : 435)
Query Neighborhood Hits	244	Target Neighborhood Hits	332	Shared Neighborhood Hits	101
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM2_MOUSE
θ value	θ > 10 (rank : 416)	NC score	0.088561 (rank : 342)
Query Neighborhood Hits	244	Target Neighborhood Hits	420	Shared Neighborhood Hits	137
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM3_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.102060 (rank : 298)
Query Neighborhood Hits	244	Target Neighborhood Hits	378	Shared Neighborhood Hits	134
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MAMC2_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.080272 (rank : 367)
Query Neighborhood Hits	244	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MAMC2_MOUSE
θ value	θ > 10 (rank : 419)	NC score	0.082389 (rank : 362)
Query Neighborhood Hits	244	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MAP4_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.066083 (rank : 422)
Query Neighborhood Hits	244	Target Neighborhood Hits	428	Shared Neighborhood Hits	7
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MAP4_MOUSE
θ value	θ > 10 (rank : 421)	NC score	0.062068 (rank : 445)
Query Neighborhood Hits	244	Target Neighborhood Hits	409	Shared Neighborhood Hits	7
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MASP1_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.059869 (rank : 459)
Query Neighborhood Hits	244	Target Neighborhood Hits	369	Shared Neighborhood Hits	109
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

MASP1_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.058848 (rank : 462)
Query Neighborhood Hits	244	Target Neighborhood Hits	364	Shared Neighborhood Hits	108
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

MASP2_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.063078 (rank : 438)
Query Neighborhood Hits	244	Target Neighborhood Hits	364	Shared Neighborhood Hits	108
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MASP2_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.061899 (rank : 447)
Query Neighborhood Hits	244	Target Neighborhood Hits	382	Shared Neighborhood Hits	110
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MATN1_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.161777 (rank : 201)
Query Neighborhood Hits	244	Target Neighborhood Hits	191	Shared Neighborhood Hits	107
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN1_MOUSE
θ value	θ > 10 (rank : 427)	NC score	0.160887 (rank : 206)
Query Neighborhood Hits	244	Target Neighborhood Hits	186	Shared Neighborhood Hits	103
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MAVS_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.050814 (rank : 501)
Query Neighborhood Hits	244	Target Neighborhood Hits	271	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

MCSP_MOUSE
θ value	θ > 10 (rank : 429)	NC score	0.141885 (rank : 239)
Query Neighborhood Hits	244	Target Neighborhood Hits	108	Shared Neighborhood Hits	34
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MDC1_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.077233 (rank : 374)
Query Neighborhood Hits	244	Target Neighborhood Hits	1446	Shared Neighborhood Hits	13
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MDC1_MOUSE
θ value	θ > 10 (rank : 431)	NC score	0.068833 (rank : 409)
Query Neighborhood Hits	244	Target Neighborhood Hits	998	Shared Neighborhood Hits	17
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MEGF8_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.187267 (rank : 164)
Query Neighborhood Hits	244	Target Neighborhood Hits	528	Shared Neighborhood Hits	177
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.189144 (rank : 157)
Query Neighborhood Hits	244	Target Neighborhood Hits	520	Shared Neighborhood Hits	174
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF9_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.125393 (rank : 260)
Query Neighborhood Hits	244	Target Neighborhood Hits	557	Shared Neighborhood Hits	142
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEP1A_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.058381 (rank : 464)
Query Neighborhood Hits	244	Target Neighborhood Hits	162	Shared Neighborhood Hits	76
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

MEP1A_MOUSE
θ value	θ > 10 (rank : 436)	NC score	0.057863 (rank : 466)
Query Neighborhood Hits	244	Target Neighborhood Hits	166	Shared Neighborhood Hits	77
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

MFGM_MOUSE
θ value	θ > 10 (rank : 437)	NC score	0.094556 (rank : 320)
Query Neighborhood Hits	244	Target Neighborhood Hits	233	Shared Neighborhood Hits	89
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

MFRP_HUMAN
θ value	θ > 10 (rank : 438)	NC score	0.082606 (rank : 360)
Query Neighborhood Hits	244	Target Neighborhood Hits	165	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_MOUSE
θ value	θ > 10 (rank : 439)	NC score	0.072539 (rank : 390)
Query Neighborhood Hits	244	Target Neighborhood Hits	166	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MT1_MOUSE
θ value	θ > 10 (rank : 440)	NC score	0.059194 (rank : 461)
Query Neighborhood Hits	244	Target Neighborhood Hits	72	Shared Neighborhood Hits	17
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

MT3_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.069080 (rank : 407)
Query Neighborhood Hits	244	Target Neighborhood Hits	82	Shared Neighborhood Hits	21
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

MT4_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.095484 (rank : 316)
Query Neighborhood Hits	244	Target Neighborhood Hits	83	Shared Neighborhood Hits	27
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MUC13_MOUSE
θ value	θ > 10 (rank : 443)	NC score	0.055735 (rank : 477)
Query Neighborhood Hits	244	Target Neighborhood Hits	447	Shared Neighborhood Hits	97
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

MUCEN_MOUSE
θ value	θ > 10 (rank : 444)	NC score	0.056458 (rank : 475)
Query Neighborhood Hits	244	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R0H2, Q78KL2, Q9DCN9, Q9ULC1, Q9Z2I1	Gene names	Emcn, Muc14
Domain Architecture	No domain graphic available
Description	Endomucin precursor (Endomucin-1/2).

NACAM_MOUSE
θ value	θ > 10 (rank : 445)	NC score	0.069741 (rank : 404)
Query Neighborhood Hits	244	Target Neighborhood Hits	1866	Shared Neighborhood Hits	22
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NDP_MOUSE
θ value	θ > 10 (rank : 446)	NC score	0.050282 (rank : 507)
Query Neighborhood Hits	244	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	P48744	Gene names	Ndp, Ndph
Domain Architecture
Description	Norrin precursor (Norrie disease protein homolog).

NET2_HUMAN
θ value	θ > 10 (rank : 447)	NC score	0.050147 (rank : 509)
Query Neighborhood Hits	244	Target Neighborhood Hits	194	Shared Neighborhood Hits	76
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

NET2_MOUSE
θ value	θ > 10 (rank : 448)	NC score	0.050016 (rank : 511)
Query Neighborhood Hits	244	Target Neighborhood Hits	193	Shared Neighborhood Hits	78
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

NETO1_HUMAN
θ value	θ > 10 (rank : 449)	NC score	0.063154 (rank : 437)
Query Neighborhood Hits	244	Target Neighborhood Hits	110	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
θ value	θ > 10 (rank : 450)	NC score	0.062186 (rank : 444)
Query Neighborhood Hits	244	Target Neighborhood Hits	109	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO2_HUMAN
θ value	θ > 10 (rank : 451)	NC score	0.063010 (rank : 439)
Query Neighborhood Hits	244	Target Neighborhood Hits	109	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
θ value	θ > 10 (rank : 452)	NC score	0.062419 (rank : 443)
Query Neighborhood Hits	244	Target Neighborhood Hits	113	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NRP1_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.070283 (rank : 401)
Query Neighborhood Hits	244	Target Neighborhood Hits	119	Shared Neighborhood Hits	22
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

NRP1_MOUSE
θ value	θ > 10 (rank : 454)	NC score	0.065918 (rank : 423)
Query Neighborhood Hits	244	Target Neighborhood Hits	120	Shared Neighborhood Hits	21
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NRP2_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.072577 (rank : 389)
Query Neighborhood Hits	244	Target Neighborhood Hits	120	Shared Neighborhood Hits	22
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_MOUSE
θ value	θ > 10 (rank : 456)	NC score	0.061808 (rank : 448)
Query Neighborhood Hits	244	Target Neighborhood Hits	113	Shared Neighborhood Hits	22
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NTNG1_HUMAN
θ value	θ > 10 (rank : 457)	NC score	0.067800 (rank : 412)
Query Neighborhood Hits	244	Target Neighborhood Hits	247	Shared Neighborhood Hits	90
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG1_MOUSE
θ value	θ > 10 (rank : 458)	NC score	0.066357 (rank : 420)
Query Neighborhood Hits	244	Target Neighborhood Hits	246	Shared Neighborhood Hits	86
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG2_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.087633 (rank : 348)
Query Neighborhood Hits	244	Target Neighborhood Hits	276	Shared Neighborhood Hits	103
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

PCOC1_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.062431 (rank : 442)
Query Neighborhood Hits	244	Target Neighborhood Hits	146	Shared Neighborhood Hits	17
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC1_MOUSE
θ value	θ > 10 (rank : 461)	NC score	0.062612 (rank : 441)
Query Neighborhood Hits	244	Target Neighborhood Hits	100	Shared Neighborhood Hits	18
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC2_HUMAN
θ value	θ > 10 (rank : 462)	NC score	0.064699 (rank : 426)
Query Neighborhood Hits	244	Target Neighborhood Hits	73	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC2_MOUSE
θ value	θ > 10 (rank : 463)	NC score	0.063570 (rank : 434)
Query Neighborhood Hits	244	Target Neighborhood Hits	73	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PERT_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.111084 (rank : 276)
Query Neighborhood Hits	244	Target Neighborhood Hits	221	Shared Neighborhood Hits	116
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PERT_MOUSE
θ value	θ > 10 (rank : 465)	NC score	0.104038 (rank : 292)
Query Neighborhood Hits	244	Target Neighborhood Hits	221	Shared Neighborhood Hits	111
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PGBM_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.101222 (rank : 302)
Query Neighborhood Hits	244	Target Neighborhood Hits	1113	Shared Neighborhood Hits	156
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGBM_MOUSE
θ value	θ > 10 (rank : 467)	NC score	0.105386 (rank : 288)
Query Neighborhood Hits	244	Target Neighborhood Hits	1073	Shared Neighborhood Hits	168
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGCB_HUMAN
θ value	θ > 10 (rank : 468)	NC score	0.054145 (rank : 481)
Query Neighborhood Hits	244	Target Neighborhood Hits	478	Shared Neighborhood Hits	81
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

PGCB_MOUSE
θ value	θ > 10 (rank : 469)	NC score	0.061173 (rank : 453)
Query Neighborhood Hits	244	Target Neighborhood Hits	459	Shared Neighborhood Hits	89
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

PHXR5_MOUSE
θ value	θ > 10 (rank : 470)	NC score	0.094049 (rank : 321)
Query Neighborhood Hits	244	Target Neighborhood Hits	102	Shared Neighborhood Hits	66
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

PODXL_HUMAN
θ value	θ > 10 (rank : 471)	NC score	0.060410 (rank : 456)
Query Neighborhood Hits	244	Target Neighborhood Hits	191	Shared Neighborhood Hits	7
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

PROC_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.069045 (rank : 408)
Query Neighborhood Hits	244	Target Neighborhood Hits	406	Shared Neighborhood Hits	134
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROZ_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.151758 (rank : 218)
Query Neighborhood Hits	244	Target Neighborhood Hits	422	Shared Neighborhood Hits	142
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_MOUSE
θ value	θ > 10 (rank : 474)	NC score	0.151234 (rank : 220)
Query Neighborhood Hits	244	Target Neighborhood Hits	410	Shared Neighborhood Hits	138
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

RECK_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.150994 (rank : 221)
Query Neighborhood Hits	244	Target Neighborhood Hits	189	Shared Neighborhood Hits	90
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

RECK_MOUSE
θ value	θ > 10 (rank : 476)	NC score	0.141860 (rank : 240)
Query Neighborhood Hits	244	Target Neighborhood Hits	158	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

RSPO1_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.050193 (rank : 508)
Query Neighborhood Hits	244	Target Neighborhood Hits	101	Shared Neighborhood Hits	37
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

RSPO3_HUMAN
θ value	θ > 10 (rank : 478)	NC score	0.061688 (rank : 449)
Query Neighborhood Hits	244	Target Neighborhood Hits	128	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

RSPO3_MOUSE
θ value	θ > 10 (rank : 479)	NC score	0.052596 (rank : 488)
Query Neighborhood Hits	244	Target Neighborhood Hits	120	Shared Neighborhood Hits	46
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

RSPO4_MOUSE
θ value	θ > 10 (rank : 480)	NC score	0.050650 (rank : 504)
Query Neighborhood Hits	244	Target Neighborhood Hits	110	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

SELPL_MOUSE
θ value	θ > 10 (rank : 481)	NC score	0.060618 (rank : 455)
Query Neighborhood Hits	244	Target Neighborhood Hits	588	Shared Neighborhood Hits	10
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SLIT1_MOUSE
θ value	θ > 10 (rank : 482)	NC score	0.145881 (rank : 228)
Query Neighborhood Hits	244	Target Neighborhood Hits	715	Shared Neighborhood Hits	178
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

SLIT2_MOUSE
θ value	θ > 10 (rank : 483)	NC score	0.138759 (rank : 246)
Query Neighborhood Hits	244	Target Neighborhood Hits	684	Shared Neighborhood Hits	167
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT3_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.136482 (rank : 249)
Query Neighborhood Hits	244	Target Neighborhood Hits	682	Shared Neighborhood Hits	163
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

SMOC1_HUMAN
θ value	θ > 10 (rank : 485)	NC score	0.055622 (rank : 478)
Query Neighborhood Hits	244	Target Neighborhood Hits	81	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

SMOC2_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.051103 (rank : 500)
Query Neighborhood Hits	244	Target Neighborhood Hits	88	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

SMOC2_MOUSE
θ value	θ > 10 (rank : 487)	NC score	0.051438 (rank : 497)
Query Neighborhood Hits	244	Target Neighborhood Hits	81	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).

SON_MOUSE
θ value	θ > 10 (rank : 488)	NC score	0.056801 (rank : 471)
Query Neighborhood Hits	244	Target Neighborhood Hits	957	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SPR2B_MOUSE
θ value	θ > 10 (rank : 489)	NC score	0.056659 (rank : 472)
Query Neighborhood Hits	244	Target Neighborhood Hits	51	Shared Neighborhood Hits	16
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

SPR2D_MOUSE
θ value	θ > 10 (rank : 490)	NC score	0.091532 (rank : 331)
Query Neighborhood Hits	244	Target Neighborhood Hits	61	Shared Neighborhood Hits	19
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

SPR2E_MOUSE
θ value	θ > 10 (rank : 491)	NC score	0.093708 (rank : 324)
Query Neighborhood Hits	244	Target Neighborhood Hits	45	Shared Neighborhood Hits	16
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

SPR2F_MOUSE
θ value	θ > 10 (rank : 492)	NC score	0.081516 (rank : 364)
Query Neighborhood Hits	244	Target Neighborhood Hits	43	Shared Neighborhood Hits	12
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

SPR2G_MOUSE
θ value	θ > 10 (rank : 493)	NC score	0.063262 (rank : 436)
Query Neighborhood Hits	244	Target Neighborhood Hits	53	Shared Neighborhood Hits	18
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

SPR2H_MOUSE
θ value	θ > 10 (rank : 494)	NC score	0.061432 (rank : 451)
Query Neighborhood Hits	244	Target Neighborhood Hits	82	Shared Neighborhood Hits	18
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

SPR2I_MOUSE
θ value	θ > 10 (rank : 495)	NC score	0.093985 (rank : 322)
Query Neighborhood Hits	244	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

ST14_HUMAN
θ value	θ > 10 (rank : 496)	NC score	0.080092 (rank : 368)
Query Neighborhood Hits	244	Target Neighborhood Hits	409	Shared Neighborhood Hits	118
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

SUSD1_HUMAN
θ value	θ > 10 (rank : 497)	NC score	0.214723 (rank : 135)
Query Neighborhood Hits	244	Target Neighborhood Hits	285	Shared Neighborhood Hits	128
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TDGF1_HUMAN
θ value	θ > 10 (rank : 498)	NC score	0.052201 (rank : 489)
Query Neighborhood Hits	244	Target Neighborhood Hits	132	Shared Neighborhood Hits	60
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

TDGF1_MOUSE
θ value	θ > 10 (rank : 499)	NC score	0.062926 (rank : 440)
Query Neighborhood Hits	244	Target Neighborhood Hits	146	Shared Neighborhood Hits	65
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

TDGF2_HUMAN
θ value	θ > 10 (rank : 500)	NC score	0.050500 (rank : 505)
Query Neighborhood Hits	244	Target Neighborhood Hits	131	Shared Neighborhood Hits	60
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

TEFF2_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.066378 (rank : 419)
Query Neighborhood Hits	244	Target Neighborhood Hits	211	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
θ value	θ > 10 (rank : 502)	NC score	0.067784 (rank : 413)
Query Neighborhood Hits	244	Target Neighborhood Hits	214	Shared Neighborhood Hits	76
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TENA_HUMAN
θ value	θ > 10 (rank : 503)	NC score	0.172226 (rank : 186)
Query Neighborhood Hits	244	Target Neighborhood Hits	631	Shared Neighborhood Hits	180
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENA_MOUSE
θ value	θ > 10 (rank : 504)	NC score	0.161887 (rank : 200)
Query Neighborhood Hits	244	Target Neighborhood Hits	596	Shared Neighborhood Hits	174
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TENN_HUMAN
θ value	θ > 10 (rank : 505)	NC score	0.064308 (rank : 430)
Query Neighborhood Hits	244	Target Neighborhood Hits	453	Shared Neighborhood Hits	134
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENN_MOUSE
θ value	θ > 10 (rank : 506)	NC score	0.075554 (rank : 381)
Query Neighborhood Hits	244	Target Neighborhood Hits	484	Shared Neighborhood Hits	136
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENR_HUMAN
θ value	θ > 10 (rank : 507)	NC score	0.100260 (rank : 306)
Query Neighborhood Hits	244	Target Neighborhood Hits	526	Shared Neighborhood Hits	152
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TENR_MOUSE
θ value	θ > 10 (rank : 508)	NC score	0.103518 (rank : 294)
Query Neighborhood Hits	244	Target Neighborhood Hits	531	Shared Neighborhood Hits	153
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

TGBR3_HUMAN
θ value	θ > 10 (rank : 509)	NC score	0.109369 (rank : 278)
Query Neighborhood Hits	244	Target Neighborhood Hits	44	Shared Neighborhood Hits	13
SwissProt Accessions	Q03167, Q5T2T4, Q5U731, Q9UGI2	Gene names	TGFBR3
Domain Architecture
Description	TGF-beta receptor type III precursor (TGFR-3) (Transforming growth factor beta receptor III) (Betaglycan).

TINAG_HUMAN
θ value	θ > 10 (rank : 510)	NC score	0.073256 (rank : 386)
Query Neighborhood Hits	244	Target Neighborhood Hits	63	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UJW2, Q9UJW1, Q9ULZ4	Gene names	TINAG
Domain Architecture
Description	Tubulointerstitial nephritis antigen (TIN-Ag).

TNR16_HUMAN
θ value	θ > 10 (rank : 511)	NC score	0.058161 (rank : 465)
Query Neighborhood Hits	244	Target Neighborhood Hits	183	Shared Neighborhood Hits	56
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR21_MOUSE
θ value	θ > 10 (rank : 512)	NC score	0.057144 (rank : 469)
Query Neighborhood Hits	244	Target Neighborhood Hits	108	Shared Neighborhood Hits	29
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR25_HUMAN
θ value	θ > 10 (rank : 513)	NC score	0.091400 (rank : 332)
Query Neighborhood Hits	244	Target Neighborhood Hits	172	Shared Neighborhood Hits	54
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TNR8_MOUSE
θ value	θ > 10 (rank : 514)	NC score	0.073750 (rank : 383)
Query Neighborhood Hits	244	Target Neighborhood Hits	208	Shared Neighborhood Hits	55
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TNR9_HUMAN
θ value	θ > 10 (rank : 515)	NC score	0.088151 (rank : 346)
Query Neighborhood Hits	244	Target Neighborhood Hits	166	Shared Neighborhood Hits	52
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TSG6_HUMAN
θ value	θ > 10 (rank : 516)	NC score	0.070371 (rank : 400)
Query Neighborhood Hits	244	Target Neighborhood Hits	91	Shared Neighborhood Hits	22
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
θ value	θ > 10 (rank : 517)	NC score	0.070463 (rank : 399)
Query Neighborhood Hits	244	Target Neighborhood Hits	91	Shared Neighborhood Hits	21
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

TSP2_HUMAN
θ value	θ > 10 (rank : 518)	NC score	0.154802 (rank : 215)
Query Neighborhood Hits	244	Target Neighborhood Hits	359	Shared Neighborhood Hits	143
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP2_MOUSE
θ value	θ > 10 (rank : 519)	NC score	0.155135 (rank : 214)
Query Neighborhood Hits	244	Target Neighborhood Hits	352	Shared Neighborhood Hits	137
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP3_HUMAN
θ value	θ > 10 (rank : 520)	NC score	0.150832 (rank : 223)
Query Neighborhood Hits	244	Target Neighborhood Hits	250	Shared Neighborhood Hits	120
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_MOUSE
θ value	θ > 10 (rank : 521)	NC score	0.150885 (rank : 222)
Query Neighborhood Hits	244	Target Neighborhood Hits	247	Shared Neighborhood Hits	126
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP4_HUMAN
θ value	θ > 10 (rank : 522)	NC score	0.158121 (rank : 211)
Query Neighborhood Hits	244	Target Neighborhood Hits	277	Shared Neighborhood Hits	130
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_MOUSE
θ value	θ > 10 (rank : 523)	NC score	0.162404 (rank : 199)
Query Neighborhood Hits	244	Target Neighborhood Hits	276	Shared Neighborhood Hits	136
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

USH2A_HUMAN
θ value	θ > 10 (rank : 524)	NC score	0.092772 (rank : 327)
Query Neighborhood Hits	244	Target Neighborhood Hits	600	Shared Neighborhood Hits	133
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

USH2A_MOUSE
θ value	θ > 10 (rank : 525)	NC score	0.102307 (rank : 296)
Query Neighborhood Hits	244	Target Neighborhood Hits	626	Shared Neighborhood Hits	150
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

VEGFC_HUMAN
θ value	θ > 10 (rank : 526)	NC score	0.088542 (rank : 343)
Query Neighborhood Hits	244	Target Neighborhood Hits	128	Shared Neighborhood Hits	59
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

VEGFC_MOUSE
θ value	θ > 10 (rank : 527)	NC score	0.060296 (rank : 457)
Query Neighborhood Hits	244	Target Neighborhood Hits	119	Shared Neighborhood Hits	54
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

VITRN_HUMAN
θ value	θ > 10 (rank : 528)	NC score	0.066263 (rank : 421)
Query Neighborhood Hits	244	Target Neighborhood Hits	63	Shared Neighborhood Hits	9
SwissProt Accessions	Q6UXI7, Q6P7T3, Q96DT1	Gene names	VIT
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

VITRN_MOUSE
θ value	θ > 10 (rank : 529)	NC score	0.072021 (rank : 394)
Query Neighborhood Hits	244	Target Neighborhood Hits	68	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VHI5, Q3TZ47, Q8BQ41, Q8K047, Q9CYZ1	Gene names	Vit
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

WFDC3_HUMAN
θ value	θ > 10 (rank : 530)	NC score	0.091284 (rank : 333)
Query Neighborhood Hits	244	Target Neighborhood Hits	138	Shared Neighborhood Hits	70
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

WIF1_HUMAN
θ value	θ > 10 (rank : 531)	NC score	0.179114 (rank : 178)
Query Neighborhood Hits	244	Target Neighborhood Hits	392	Shared Neighborhood Hits	159
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_MOUSE
θ value	θ > 10 (rank : 532)	NC score	0.172764 (rank : 184)
Query Neighborhood Hits	244	Target Neighborhood Hits	393	Shared Neighborhood Hits	151
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WISP3_HUMAN
θ value	θ > 10 (rank : 533)	NC score	0.070078 (rank : 402)
Query Neighborhood Hits	244	Target Neighborhood Hits	87	Shared Neighborhood Hits	23
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

ZP3_MOUSE
θ value	θ > 10 (rank : 534)	NC score	0.070969 (rank : 396)
Query Neighborhood Hits	244	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	P10761	Gene names	Zp3, Zp-3, Zpc
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 precursor (Zona pellucida glycoprotein ZP3) (Sperm receptor) (Zona pellucida protein C).

Hits sorted by NC score

TECTA_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	244	Target Neighborhood Hits	244	Shared Neighborhood Hits	244
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TECTA_HUMAN
NC score	0.994904 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	244	Target Neighborhood Hits	239	Shared Neighborhood Hits	209
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

ZAN_HUMAN
NC score	0.677359 (rank : 3)	θ value	1.27474e-179 (rank : 3)
Query Neighborhood Hits	244	Target Neighborhood Hits	679	Shared Neighborhood Hits	176
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

BMPER_HUMAN
NC score	0.620348 (rank : 4)	θ value	2.04573e-44 (rank : 15)
Query Neighborhood Hits	244	Target Neighborhood Hits	175	Shared Neighborhood Hits	94
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

BMPER_MOUSE
NC score	0.620300 (rank : 5)	θ value	1.19932e-44 (rank : 14)
Query Neighborhood Hits	244	Target Neighborhood Hits	194	Shared Neighborhood Hits	105
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

ZAN_MOUSE
NC score	0.614464 (rank : 6)	θ value	2.04937e-153 (rank : 4)
Query Neighborhood Hits	244	Target Neighborhood Hits	808	Shared Neighborhood Hits	206
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

VWF_HUMAN
NC score	0.611773 (rank : 7)	θ value	1.19101e-68 (rank : 7)
Query Neighborhood Hits	244	Target Neighborhood Hits	396	Shared Neighborhood Hits	152
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

GP2_MOUSE
NC score	0.609436 (rank : 8)	θ value	8.85319e-56 (rank : 11)
Query Neighborhood Hits	244	Target Neighborhood Hits	29	Shared Neighborhood Hits	23
SwissProt Accessions	Q9D733	Gene names	Gp2
Domain Architecture	No domain graphic available
Description	Pancreatic secretory granule membrane major glycoprotein GP2 precursor (Pancreatic zymogen granule membrane protein GP-2).

VWF_MOUSE
NC score	0.608033 (rank : 9)	θ value	1.31376e-75 (rank : 5)
Query Neighborhood Hits	244	Target Neighborhood Hits	381	Shared Neighborhood Hits	150
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

GP2_HUMAN
NC score	0.607696 (rank : 10)	θ value	9.16162e-53 (rank : 13)
Query Neighborhood Hits	244	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	P55259, Q13338, Q9UIF1	Gene names	GP2
Domain Architecture
Description	Pancreatic secretory granule membrane major glycoprotein GP2 precursor (Pancreatic zymogen granule membrane protein GP-2) (ZAP75).

MUC5B_HUMAN
NC score	0.586198 (rank : 11)	θ value	4.85792e-54 (rank : 12)
Query Neighborhood Hits	244	Target Neighborhood Hits	1020	Shared Neighborhood Hits	158
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MUC2_HUMAN
NC score	0.545068 (rank : 12)	θ value	2.7521e-57 (rank : 8)
Query Neighborhood Hits	244	Target Neighborhood Hits	906	Shared Neighborhood Hits	121
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

UROM_MOUSE
NC score	0.537913 (rank : 13)	θ value	6.77864e-56 (rank : 10)
Query Neighborhood Hits	244	Target Neighborhood Hits	276	Shared Neighborhood Hits	154
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_HUMAN
NC score	0.527963 (rank : 14)	θ value	3.0428e-56 (rank : 9)
Query Neighborhood Hits	244	Target Neighborhood Hits	284	Shared Neighborhood Hits	156
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

TECTB_MOUSE
NC score	0.485753 (rank : 15)	θ value	2.13179e-17 (rank : 20)
Query Neighborhood Hits	244	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	O08524	Gene names	Tectb
Domain Architecture
Description	Beta-tectorin precursor.

SSPO_MOUSE
NC score	0.483048 (rank : 16)	θ value	4.22625e-74 (rank : 6)
Query Neighborhood Hits	244	Target Neighborhood Hits	800	Shared Neighborhood Hits	190
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

TECTB_HUMAN
NC score	0.480893 (rank : 17)	θ value	1.16975e-15 (rank : 22)
Query Neighborhood Hits	244	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q96PL2	Gene names	TECTB
Domain Architecture
Description	Beta-tectorin precursor.

UROL1_MOUSE
NC score	0.441720 (rank : 18)	θ value	6.00763e-12 (rank : 30)
Query Neighborhood Hits	244	Target Neighborhood Hits	235	Shared Neighborhood Hits	116
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

UROL1_HUMAN
NC score	0.431804 (rank : 19)	θ value	5.43371e-13 (rank : 29)
Query Neighborhood Hits	244	Target Neighborhood Hits	213	Shared Neighborhood Hits	104
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

ZP4_HUMAN
NC score	0.413017 (rank : 20)	θ value	1.24977e-17 (rank : 19)
Query Neighborhood Hits	244	Target Neighborhood Hits	36	Shared Neighborhood Hits	21
SwissProt Accessions	Q12836	Gene names	ZP4, ZPB
Domain Architecture
Description	Zona pellucida sperm-binding protein 4 precursor (Zona pellucida sperm-binding protein B).

ZP2_MOUSE
NC score	0.403307 (rank : 21)	θ value	4.16044e-13 (rank : 28)
Query Neighborhood Hits	244	Target Neighborhood Hits	28	Shared Neighborhood Hits	21
SwissProt Accessions	P20239	Gene names	Zp2, Zp-2, Zpa
Domain Architecture
Description	Zona pellucida sperm-binding protein 2 precursor (Zona pellucida glycoprotein ZP2) (Zona pellucida protein A).

ZP2_HUMAN
NC score	0.380529 (rank : 22)	θ value	6.41864e-14 (rank : 26)
Query Neighborhood Hits	244	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	Q05996	Gene names	ZP2, ZPA
Domain Architecture
Description	Zona pellucida sperm-binding protein 2 precursor (Zona pellucida glycoprotein ZP2) (Zona pellucida protein A).

NID2_HUMAN
NC score	0.350101 (rank : 23)	θ value	1.09232e-21 (rank : 17)
Query Neighborhood Hits	244	Target Neighborhood Hits	456	Shared Neighborhood Hits	153
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID2_MOUSE
NC score	0.346774 (rank : 24)	θ value	8.36355e-22 (rank : 16)
Query Neighborhood Hits	244	Target Neighborhood Hits	338	Shared Neighborhood Hits	146
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NID1_MOUSE
NC score	0.336772 (rank : 25)	θ value	4.29542e-18 (rank : 18)
Query Neighborhood Hits	244	Target Neighborhood Hits	335	Shared Neighborhood Hits	146
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_HUMAN
NC score	0.329999 (rank : 26)	θ value	9.90251e-15 (rank : 25)
Query Neighborhood Hits	244	Target Neighborhood Hits	329	Shared Neighborhood Hits	146
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

CUZD1_HUMAN
NC score	0.323495 (rank : 27)	θ value	3.07829e-16 (rank : 21)
Query Neighborhood Hits	244	Target Neighborhood Hits	89	Shared Neighborhood Hits	34
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

NELL1_HUMAN
NC score	0.323321 (rank : 28)	θ value	0.00228821 (rank : 49)
Query Neighborhood Hits	244	Target Neighborhood Hits	451	Shared Neighborhood Hits	189
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

CUZD1_MOUSE
NC score	0.322732 (rank : 29)	θ value	3.40345e-15 (rank : 23)
Query Neighborhood Hits	244	Target Neighborhood Hits	91	Shared Neighborhood Hits	33
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

ZP1_MOUSE
NC score	0.317386 (rank : 30)	θ value	1.69304e-06 (rank : 32)
Query Neighborhood Hits	244	Target Neighborhood Hits	43	Shared Neighborhood Hits	22
SwissProt Accessions	Q62005, Q62016	Gene names	Zp1
Domain Architecture
Description	Zona pellucida sperm-binding protein 1 precursor (Zona pellucida glycoprotein 1) (Zp-1).

ZP1_HUMAN
NC score	0.309368 (rank : 31)	θ value	1.29631e-06 (rank : 31)
Query Neighborhood Hits	244	Target Neighborhood Hits	39	Shared Neighborhood Hits	19
SwissProt Accessions	P60852	Gene names	ZP1
Domain Architecture	No domain graphic available
Description	Zona pellucida sperm-binding protein 1 precursor (Zona pellucida glycoprotein 1) (Zp-1).

NELL2_MOUSE
NC score	0.308305 (rank : 32)	θ value	0.00390308 (rank : 51)
Query Neighborhood Hits	244	Target Neighborhood Hits	436	Shared Neighborhood Hits	180
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NELL2_HUMAN
NC score	0.304472 (rank : 33)	θ value	0.0252991 (rank : 74)
Query Neighborhood Hits	244	Target Neighborhood Hits	449	Shared Neighborhood Hits	184
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

FBLN2_MOUSE
NC score	0.283891 (rank : 34)	θ value	0.0193708 (rank : 67)
Query Neighborhood Hits	244	Target Neighborhood Hits	505	Shared Neighborhood Hits	168
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

TRBM_MOUSE
NC score	0.283114 (rank : 35)	θ value	0.0563607 (rank : 89)
Query Neighborhood Hits	244	Target Neighborhood Hits	361	Shared Neighborhood Hits	173
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

FBLN2_HUMAN
NC score	0.282508 (rank : 36)	θ value	0.000158464 (rank : 37)
Query Neighborhood Hits	244	Target Neighborhood Hits	392	Shared Neighborhood Hits	167
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

TRBM_HUMAN
NC score	0.280930 (rank : 37)	θ value	0.00102713 (rank : 42)
Query Neighborhood Hits	244	Target Neighborhood Hits	339	Shared Neighborhood Hits	170
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

MEGF6_HUMAN
NC score	0.280899 (rank : 38)	θ value	0.00665767 (rank : 56)
Query Neighborhood Hits	244	Target Neighborhood Hits	671	Shared Neighborhood Hits	207
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

SCUB3_MOUSE
NC score	0.280872 (rank : 39)	θ value	0.0431538 (rank : 82)
Query Neighborhood Hits	244	Target Neighborhood Hits	442	Shared Neighborhood Hits	180
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

CRIM1_HUMAN
NC score	0.280469 (rank : 40)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	244	Target Neighborhood Hits	362	Shared Neighborhood Hits	136
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

SCUB3_HUMAN
NC score	0.279935 (rank : 41)	θ value	0.0252991 (rank : 75)
Query Neighborhood Hits	244	Target Neighborhood Hits	428	Shared Neighborhood Hits	175
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

KR104_HUMAN
NC score	0.278912 (rank : 42)	θ value	0.0736092 (rank : 95)
Query Neighborhood Hits	244	Target Neighborhood Hits	313	Shared Neighborhood Hits	133
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

EGF_HUMAN
NC score	0.278127 (rank : 43)	θ value	0.00665767 (rank : 55)
Query Neighborhood Hits	244	Target Neighborhood Hits	343	Shared Neighborhood Hits	162
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

LCE1A_HUMAN
NC score	0.274396 (rank : 44)	θ value	5.27518 (rank : 215)
Query Neighborhood Hits	244	Target Neighborhood Hits	47	Shared Neighborhood Hits	27
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

FBN2_MOUSE
NC score	0.273345 (rank : 45)	θ value	0.279714 (rank : 123)
Query Neighborhood Hits	244	Target Neighborhood Hits	549	Shared Neighborhood Hits	206
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_HUMAN
NC score	0.272626 (rank : 46)	θ value	0.21417 (rank : 114)
Query Neighborhood Hits	244	Target Neighborhood Hits	560	Shared Neighborhood Hits	205
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

MATN2_MOUSE
NC score	0.272024 (rank : 47)	θ value	0.00228821 (rank : 47)
Query Neighborhood Hits	244	Target Neighborhood Hits	356	Shared Neighborhood Hits	157
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

FBN1_HUMAN
NC score	0.269757 (rank : 48)	θ value	0.0563607 (rank : 85)
Query Neighborhood Hits	244	Target Neighborhood Hits	557	Shared Neighborhood Hits	204
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

EGF_MOUSE
NC score	0.269547 (rank : 49)	θ value	0.21417 (rank : 112)
Query Neighborhood Hits	244	Target Neighborhood Hits	358	Shared Neighborhood Hits	161
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

FBN3_HUMAN
NC score	0.268777 (rank : 50)	θ value	0.365318 (rank : 135)
Query Neighborhood Hits	244	Target Neighborhood Hits	543	Shared Neighborhood Hits	204
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FBN1_MOUSE
NC score	0.268401 (rank : 51)	θ value	0.0330416 (rank : 76)
Query Neighborhood Hits	244	Target Neighborhood Hits	563	Shared Neighborhood Hits	201
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBLN1_MOUSE
NC score	0.266846 (rank : 52)	θ value	0.0431538 (rank : 80)
Query Neighborhood Hits	244	Target Neighborhood Hits	329	Shared Neighborhood Hits	162
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

LRP2_HUMAN
NC score	0.265976 (rank : 53)	θ value	0.0113563 (rank : 61)
Query Neighborhood Hits	244	Target Neighborhood Hits	573	Shared Neighborhood Hits	199
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

FBLN5_HUMAN
NC score	0.264501 (rank : 54)	θ value	0.365318 (rank : 134)
Query Neighborhood Hits	244	Target Neighborhood Hits	329	Shared Neighborhood Hits	168
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN3_HUMAN
NC score	0.264471 (rank : 55)	θ value	0.00509761 (rank : 53)
Query Neighborhood Hits	244	Target Neighborhood Hits	293	Shared Neighborhood Hits	153
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN5_MOUSE
NC score	0.264167 (rank : 56)	θ value	1.06291 (rank : 154)
Query Neighborhood Hits	244	Target Neighborhood Hits	317	Shared Neighborhood Hits	160
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

STAB1_MOUSE
NC score	0.263613 (rank : 57)	θ value	0.000461057 (rank : 38)
Query Neighborhood Hits	244	Target Neighborhood Hits	566	Shared Neighborhood Hits	193
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

KR107_HUMAN
NC score	0.263355 (rank : 58)	θ value	0.0431538 (rank : 81)
Query Neighborhood Hits	244	Target Neighborhood Hits	330	Shared Neighborhood Hits	144
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

MATN4_HUMAN
NC score	0.263326 (rank : 59)	θ value	0.0193708 (rank : 69)
Query Neighborhood Hits	244	Target Neighborhood Hits	287	Shared Neighborhood Hits	146
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MATN3_HUMAN
NC score	0.263145 (rank : 60)	θ value	0.00175202 (rank : 45)
Query Neighborhood Hits	244	Target Neighborhood Hits	268	Shared Neighborhood Hits	133
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

LDLR_HUMAN
NC score	0.262848 (rank : 61)	θ value	2.36792 (rank : 180)
Query Neighborhood Hits	244	Target Neighborhood Hits	375	Shared Neighborhood Hits	172
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP1B_HUMAN
NC score	0.262772 (rank : 62)	θ value	0.00102713 (rank : 41)
Query Neighborhood Hits	244	Target Neighborhood Hits	602	Shared Neighborhood Hits	198
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

FBLN1_HUMAN
NC score	0.262248 (rank : 63)	θ value	0.0431538 (rank : 79)
Query Neighborhood Hits	244	Target Neighborhood Hits	324	Shared Neighborhood Hits	160
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

STAB2_MOUSE
NC score	0.262246 (rank : 64)	θ value	2.44474e-05 (rank : 35)
Query Neighborhood Hits	244	Target Neighborhood Hits	528	Shared Neighborhood Hits	184
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

LTBP2_HUMAN
NC score	0.262119 (rank : 65)	θ value	0.0148317 (rank : 63)
Query Neighborhood Hits	244	Target Neighborhood Hits	552	Shared Neighborhood Hits	189
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LRP1_HUMAN
NC score	0.261143 (rank : 66)	θ value	0.000786445 (rank : 40)
Query Neighborhood Hits	244	Target Neighborhood Hits	617	Shared Neighborhood Hits	204
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

FBLN3_MOUSE
NC score	0.261007 (rank : 67)	θ value	0.00390308 (rank : 50)
Query Neighborhood Hits	244	Target Neighborhood Hits	279	Shared Neighborhood Hits	146
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

MATN2_HUMAN
NC score	0.260773 (rank : 68)	θ value	0.0148317 (rank : 64)
Query Neighborhood Hits	244	Target Neighborhood Hits	365	Shared Neighborhood Hits	155
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

C1QR1_MOUSE
NC score	0.259927 (rank : 69)	θ value	0.21417 (rank : 111)
Query Neighborhood Hits	244	Target Neighborhood Hits	342	Shared Neighborhood Hits	154
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

LRP1B_MOUSE
NC score	0.258944 (rank : 70)	θ value	0.00175202 (rank : 44)
Query Neighborhood Hits	244	Target Neighborhood Hits	606	Shared Neighborhood Hits	197
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

KR106_HUMAN
NC score	0.258563 (rank : 71)	θ value	0.163984 (rank : 108)
Query Neighborhood Hits	244	Target Neighborhood Hits	347	Shared Neighborhood Hits	152
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

FBLN4_HUMAN
NC score	0.258249 (rank : 72)	θ value	0.163984 (rank : 105)
Query Neighborhood Hits	244	Target Neighborhood Hits	278	Shared Neighborhood Hits	147
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

MATN3_MOUSE
NC score	0.257015 (rank : 73)	θ value	0.00134147 (rank : 43)
Query Neighborhood Hits	244	Target Neighborhood Hits	261	Shared Neighborhood Hits	133
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

LTBP2_MOUSE
NC score	0.255892 (rank : 74)	θ value	0.0113563 (rank : 62)
Query Neighborhood Hits	244	Target Neighborhood Hits	617	Shared Neighborhood Hits	188
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

FBLN4_MOUSE
NC score	0.254512 (rank : 75)	θ value	0.365318 (rank : 133)
Query Neighborhood Hits	244	Target Neighborhood Hits	270	Shared Neighborhood Hits	142
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

MATN4_MOUSE
NC score	0.253499 (rank : 76)	θ value	0.00228821 (rank : 48)
Query Neighborhood Hits	244	Target Neighborhood Hits	277	Shared Neighborhood Hits	135
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

SUSD2_MOUSE
NC score	0.253152 (rank : 77)	θ value	8.40245e-06 (rank : 34)
Query Neighborhood Hits	244	Target Neighborhood Hits	104	Shared Neighborhood Hits	24
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

STAB2_HUMAN
NC score	0.252465 (rank : 78)	θ value	0.00390308 (rank : 52)
Query Neighborhood Hits	244	Target Neighborhood Hits	534	Shared Neighborhood Hits	193
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

SUSD2_HUMAN
NC score	0.251924 (rank : 79)	θ value	4.92598e-06 (rank : 33)
Query Neighborhood Hits	244	Target Neighborhood Hits	99	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

CD248_HUMAN
NC score	0.250716 (rank : 80)	θ value	0.0193708 (rank : 66)
Query Neighborhood Hits	244	Target Neighborhood Hits	679	Shared Neighborhood Hits	150
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

LDLR_MOUSE
NC score	0.250325 (rank : 81)	θ value	6.88961 (rank : 226)
Query Neighborhood Hits	244	Target Neighborhood Hits	382	Shared Neighborhood Hits	167
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LTB1L_HUMAN
NC score	0.248475 (rank : 82)	θ value	1.06291 (rank : 159)
Query Neighborhood Hits	244	Target Neighborhood Hits	553	Shared Neighborhood Hits	180
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP4_MOUSE
NC score	0.248432 (rank : 83)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	244	Target Neighborhood Hits	607	Shared Neighborhood Hits	181
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

LTB1S_HUMAN
NC score	0.248306 (rank : 84)	θ value	1.06291 (rank : 160)
Query Neighborhood Hits	244	Target Neighborhood Hits	502	Shared Neighborhood Hits	175
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

C1QR1_HUMAN
NC score	0.247985 (rank : 85)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	244	Target Neighborhood Hits	493	Shared Neighborhood Hits	163
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

LTB1S_MOUSE
NC score	0.247707 (rank : 86)	θ value	0.47712 (rank : 140)
Query Neighborhood Hits	244	Target Neighborhood Hits	479	Shared Neighborhood Hits	174
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_MOUSE
NC score	0.247124 (rank : 87)	θ value	0.47712 (rank : 139)
Query Neighborhood Hits	244	Target Neighborhood Hits	514	Shared Neighborhood Hits	180
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

VLDLR_MOUSE
NC score	0.247103 (rank : 88)	θ value	0.0148317 (rank : 65)
Query Neighborhood Hits	244	Target Neighborhood Hits	360	Shared Neighborhood Hits	152
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

STAB1_HUMAN
NC score	0.246970 (rank : 89)	θ value	0.163984 (rank : 110)
Query Neighborhood Hits	244	Target Neighborhood Hits	546	Shared Neighborhood Hits	190
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

VLDLR_HUMAN
NC score	0.246817 (rank : 90)	θ value	0.0961366 (rank : 101)
Query Neighborhood Hits	244	Target Neighborhood Hits	383	Shared Neighborhood Hits	162
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

SREC_HUMAN
NC score	0.245728 (rank : 91)	θ value	0.0563607 (rank : 88)
Query Neighborhood Hits	244	Target Neighborhood Hits	645	Shared Neighborhood Hits	189
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

LRP4_HUMAN
NC score	0.245244 (rank : 92)	θ value	0.0736092 (rank : 97)
Query Neighborhood Hits	244	Target Neighborhood Hits	355	Shared Neighborhood Hits	149
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP8_MOUSE
NC score	0.244420 (rank : 93)	θ value	4.03905 (rank : 204)
Query Neighborhood Hits	244	Target Neighborhood Hits	385	Shared Neighborhood Hits	160
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

CREL1_MOUSE
NC score	0.244280 (rank : 94)	θ value	2.36792 (rank : 178)
Query Neighborhood Hits	244	Target Neighborhood Hits	524	Shared Neighborhood Hits	152
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

LRP4_MOUSE
NC score	0.244004 (rank : 95)	θ value	0.125558 (rank : 102)
Query Neighborhood Hits	244	Target Neighborhood Hits	351	Shared Neighborhood Hits	148
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

GAS6_HUMAN
NC score	0.243885 (rank : 96)	θ value	0.0736092 (rank : 93)
Query Neighborhood Hits	244	Target Neighborhood Hits	348	Shared Neighborhood Hits	153
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

LTBP3_HUMAN
NC score	0.241592 (rank : 97)	θ value	2.36792 (rank : 181)
Query Neighborhood Hits	244	Target Neighborhood Hits	502	Shared Neighborhood Hits	187
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

CREL1_HUMAN
NC score	0.241043 (rank : 98)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	244	Target Neighborhood Hits	441	Shared Neighborhood Hits	146
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

GAS6_MOUSE
NC score	0.240970 (rank : 99)	θ value	0.21417 (rank : 115)
Query Neighborhood Hits	244	Target Neighborhood Hits	343	Shared Neighborhood Hits	161
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

LTBP3_MOUSE
NC score	0.240743 (rank : 100)	θ value	2.36792 (rank : 182)
Query Neighborhood Hits	244	Target Neighborhood Hits	475	Shared Neighborhood Hits	182
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

KRA53_HUMAN
NC score	0.240386 (rank : 101)	θ value	0.0736092 (rank : 96)
Query Neighborhood Hits	244	Target Neighborhood Hits	331	Shared Neighborhood Hits	130
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

CD248_MOUSE
NC score	0.239511 (rank : 102)	θ value	0.0961366 (rank : 98)
Query Neighborhood Hits	244	Target Neighborhood Hits	578	Shared Neighborhood Hits	139
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

FRAS1_HUMAN
NC score	0.239385 (rank : 103)	θ value	0.0330416 (rank : 77)
Query Neighborhood Hits	244	Target Neighborhood Hits	759	Shared Neighborhood Hits	179
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

PROS_MOUSE
NC score	0.239204 (rank : 104)	θ value	1.81305 (rank : 175)
Query Neighborhood Hits	244	Target Neighborhood Hits	330	Shared Neighborhood Hits	151
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

JAG1_HUMAN
NC score	0.238172 (rank : 105)	θ value	0.163984 (rank : 107)
Query Neighborhood Hits	244	Target Neighborhood Hits	514	Shared Neighborhood Hits	189
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

PROS_HUMAN
NC score	0.237459 (rank : 106)	θ value	0.365318 (rank : 136)
Query Neighborhood Hits	244	Target Neighborhood Hits	340	Shared Neighborhood Hits	158
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

FRAS1_MOUSE
NC score	0.236298 (rank : 107)	θ value	0.163984 (rank : 106)
Query Neighborhood Hits	244	Target Neighborhood Hits	747	Shared Neighborhood Hits	175
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

LRP8_HUMAN
NC score	0.235742 (rank : 108)	θ value	4.03905 (rank : 203)
Query Neighborhood Hits	244	Target Neighborhood Hits	346	Shared Neighborhood Hits	150
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

JAG1_MOUSE
NC score	0.234906 (rank : 109)	θ value	0.279714 (rank : 124)
Query Neighborhood Hits	244	Target Neighborhood Hits	518	Shared Neighborhood Hits	188
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

KR102_HUMAN
NC score	0.230934 (rank : 110)	θ value	0.813845 (rank : 150)
Query Neighborhood Hits	244	Target Neighborhood Hits	264	Shared Neighborhood Hits	119
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

NOTC1_MOUSE
NC score	0.229314 (rank : 111)	θ value	0.0193708 (rank : 70)
Query Neighborhood Hits	244	Target Neighborhood Hits	916	Shared Neighborhood Hits	198
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

KR109_HUMAN
NC score	0.229024 (rank : 112)	θ value	0.813845 (rank : 151)
Query Neighborhood Hits	244	Target Neighborhood Hits	226	Shared Neighborhood Hits	108
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

PCSK5_MOUSE
NC score	0.226567 (rank : 113)	θ value	5.44631e-05 (rank : 36)
Query Neighborhood Hits	244	Target Neighborhood Hits	613	Shared Neighborhood Hits	187
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

LCE1F_HUMAN
NC score	0.226348 (rank : 114)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	244	Target Neighborhood Hits	48	Shared Neighborhood Hits	25
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

NOTC1_HUMAN
NC score	0.225688 (rank : 115)	θ value	0.00869519 (rank : 59)
Query Neighborhood Hits	244	Target Neighborhood Hits	906	Shared Neighborhood Hits	197
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

JAG2_HUMAN
NC score	0.224452 (rank : 116)	θ value	5.27518 (rank : 213)
Query Neighborhood Hits	244	Target Neighborhood Hits	491	Shared Neighborhood Hits	181
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

KR101_HUMAN
NC score	0.224374 (rank : 117)	θ value	1.38821 (rank : 164)
Query Neighborhood Hits	244	Target Neighborhood Hits	261	Shared Neighborhood Hits	113
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

SREC2_MOUSE
NC score	0.224179 (rank : 118)	θ value	0.0193708 (rank : 71)
Query Neighborhood Hits	244	Target Neighborhood Hits	605	Shared Neighborhood Hits	184
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

KRA58_HUMAN
NC score	0.222848 (rank : 119)	θ value	1.81305 (rank : 173)
Query Neighborhood Hits	244	Target Neighborhood Hits	324	Shared Neighborhood Hits	126
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

CUBN_MOUSE
NC score	0.221886 (rank : 120)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	244	Target Neighborhood Hits	477	Shared Neighborhood Hits	173
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

GRN_HUMAN
NC score	0.221338 (rank : 121)	θ value	3.0926 (rank : 190)
Query Neighborhood Hits	244	Target Neighborhood Hits	268	Shared Neighborhood Hits	148
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

CUBN_HUMAN
NC score	0.219664 (rank : 122)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	244	Target Neighborhood Hits	482	Shared Neighborhood Hits	170
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

NOTC4_HUMAN
NC score	0.218703 (rank : 123)	θ value	0.163984 (rank : 109)
Query Neighborhood Hits	244	Target Neighborhood Hits	905	Shared Neighborhood Hits	200
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC3_HUMAN
NC score	0.218048 (rank : 124)	θ value	1.06291 (rank : 161)
Query Neighborhood Hits	244	Target Neighborhood Hits	1062	Shared Neighborhood Hits	197
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

GRN_MOUSE
NC score	0.217784 (rank : 125)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	244	Target Neighborhood Hits	248	Shared Neighborhood Hits	142
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

SREC2_HUMAN
NC score	0.217556 (rank : 126)	θ value	0.00869519 (rank : 60)
Query Neighborhood Hits	244	Target Neighborhood Hits	645	Shared Neighborhood Hits	178
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

JAG2_MOUSE
NC score	0.217199 (rank : 127)	θ value	4.03905 (rank : 202)
Query Neighborhood Hits	244	Target Neighborhood Hits	504	Shared Neighborhood Hits	181
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

LCE1E_HUMAN
NC score	0.217045 (rank : 128)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	244	Target Neighborhood Hits	53	Shared Neighborhood Hits	29
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

NOTC2_MOUSE
NC score	0.216538 (rank : 129)	θ value	0.279714 (rank : 126)
Query Neighborhood Hits	244	Target Neighborhood Hits	1069	Shared Neighborhood Hits	201
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

DLL1_MOUSE
NC score	0.216420 (rank : 130)	θ value	0.279714 (rank : 121)
Query Neighborhood Hits	244	Target Neighborhood Hits	456	Shared Neighborhood Hits	185
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

NOTC3_MOUSE
NC score	0.215052 (rank : 131)	θ value	4.03905 (rank : 205)
Query Neighborhood Hits	244	Target Neighborhood Hits	975	Shared Neighborhood Hits	197
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC2_HUMAN
NC score	0.215035 (rank : 132)	θ value	0.21417 (rank : 116)
Query Neighborhood Hits	244	Target Neighborhood Hits	1113	Shared Neighborhood Hits	201
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC4_MOUSE
NC score	0.214891 (rank : 133)	θ value	1.38821 (rank : 167)
Query Neighborhood Hits	244	Target Neighborhood Hits	872	Shared Neighborhood Hits	196
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

KR10B_HUMAN
NC score	0.214763 (rank : 134)	θ value	1.06291 (rank : 156)
Query Neighborhood Hits	244	Target Neighborhood Hits	269	Shared Neighborhood Hits	121
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

SUSD1_HUMAN
NC score	0.214723 (rank : 135)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	244	Target Neighborhood Hits	285	Shared Neighborhood Hits	128
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

KRA59_HUMAN
NC score	0.213880 (rank : 136)	θ value	0.279714 (rank : 125)
Query Neighborhood Hits	244	Target Neighborhood Hits	310	Shared Neighborhood Hits	117
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KR105_HUMAN
NC score	0.209708 (rank : 137)	θ value	6.88961 (rank : 224)
Query Neighborhood Hits	244	Target Neighborhood Hits	271	Shared Neighborhood Hits	117
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

CRUM1_HUMAN
NC score	0.208970 (rank : 138)	θ value	0.163984 (rank : 104)
Query Neighborhood Hits	244	Target Neighborhood Hits	457	Shared Neighborhood Hits	176
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM2_HUMAN
NC score	0.207036 (rank : 139)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	244	Target Neighborhood Hits	453	Shared Neighborhood Hits	175
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

DMBT1_HUMAN
NC score	0.206890 (rank : 140)	θ value	9.90251e-15 (rank : 24)
Query Neighborhood Hits	244	Target Neighborhood Hits	152	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

DMBT1_MOUSE
NC score	0.206558 (rank : 141)	θ value	3.18553e-13 (rank : 27)
Query Neighborhood Hits	244	Target Neighborhood Hits	134	Shared Neighborhood Hits	35
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

DNER_HUMAN
NC score	0.205377 (rank : 142)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	244	Target Neighborhood Hits	460	Shared Neighborhood Hits	167
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DLL1_HUMAN
NC score	0.205162 (rank : 143)	θ value	0.813845 (rank : 149)
Query Neighborhood Hits	244	Target Neighborhood Hits	455	Shared Neighborhood Hits	180
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

CRUM1_MOUSE
NC score	0.203268 (rank : 144)	θ value	1.81305 (rank : 170)
Query Neighborhood Hits	244	Target Neighborhood Hits	444	Shared Neighborhood Hits	174
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

EGFL7_HUMAN
NC score	0.202952 (rank : 145)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	244	Target Neighborhood Hits	325	Shared Neighborhood Hits	151
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

DLL4_HUMAN
NC score	0.202635 (rank : 146)	θ value	1.38821 (rank : 163)
Query Neighborhood Hits	244	Target Neighborhood Hits	435	Shared Neighborhood Hits	172
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DNER_MOUSE
NC score	0.200792 (rank : 147)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	244	Target Neighborhood Hits	413	Shared Neighborhood Hits	160
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

DLL4_MOUSE
NC score	0.200430 (rank : 148)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	244	Target Neighborhood Hits	440	Shared Neighborhood Hits	172
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

KR10C_HUMAN
NC score	0.199803 (rank : 149)	θ value	0.813845 (rank : 152)
Query Neighborhood Hits	244	Target Neighborhood Hits	219	Shared Neighborhood Hits	100
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KR108_HUMAN
NC score	0.198949 (rank : 150)	θ value	8.99809 (rank : 238)
Query Neighborhood Hits	244	Target Neighborhood Hits	226	Shared Neighborhood Hits	104
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

EMR1_HUMAN
NC score	0.195942 (rank : 151)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	244	Target Neighborhood Hits	382	Shared Neighborhood Hits	151
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

DLK_HUMAN
NC score	0.195091 (rank : 152)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	244	Target Neighborhood Hits	401	Shared Neighborhood Hits	162
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLK_MOUSE
NC score	0.193334 (rank : 153)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	244	Target Neighborhood Hits	374	Shared Neighborhood Hits	158
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

KRA94_HUMAN
NC score	0.191473 (rank : 154)	θ value	0.813845 (rank : 153)
Query Neighborhood Hits	244	Target Neighborhood Hits	204	Shared Neighborhood Hits	105
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

LRP5_HUMAN
NC score	0.191242 (rank : 155)	θ value	0.00509761 (rank : 54)
Query Neighborhood Hits	244	Target Neighborhood Hits	224	Shared Neighborhood Hits	109
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

EGFL9_MOUSE
NC score	0.189751 (rank : 156)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	244	Target Neighborhood Hits	379	Shared Neighborhood Hits	156
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

MEGF8_MOUSE
NC score	0.189144 (rank : 157)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	244	Target Neighborhood Hits	520	Shared Neighborhood Hits	174
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

KRA13_HUMAN
NC score	0.189134 (rank : 158)	θ value	1.38821 (rank : 166)
Query Neighborhood Hits	244	Target Neighborhood Hits	144	Shared Neighborhood Hits	80
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

AGRIN_HUMAN
NC score	0.188944 (rank : 159)	θ value	0.00869519 (rank : 58)
Query Neighborhood Hits	244	Target Neighborhood Hits	582	Shared Neighborhood Hits	174
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

LRP5_MOUSE
NC score	0.188614 (rank : 160)	θ value	0.0563607 (rank : 86)
Query Neighborhood Hits	244	Target Neighborhood Hits	236	Shared Neighborhood Hits	113
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

DLL3_HUMAN
NC score	0.188395 (rank : 161)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	244	Target Neighborhood Hits	419	Shared Neighborhood Hits	157
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DLL3_MOUSE
NC score	0.188279 (rank : 162)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	244	Target Neighborhood Hits	399	Shared Neighborhood Hits	149
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

LCE3A_HUMAN
NC score	0.187338 (rank : 163)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	244	Target Neighborhood Hits	29	Shared Neighborhood Hits	19
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

MEGF8_HUMAN
NC score	0.187267 (rank : 164)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	244	Target Neighborhood Hits	528	Shared Neighborhood Hits	177
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

EGFL9_HUMAN
NC score	0.187168 (rank : 165)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	244	Target Neighborhood Hits	365	Shared Neighborhood Hits	155
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

SORL_MOUSE
NC score	0.187068 (rank : 166)	θ value	5.27518 (rank : 217)
Query Neighborhood Hits	244	Target Neighborhood Hits	439	Shared Neighborhood Hits	142
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

KR511_HUMAN
NC score	0.186671 (rank : 167)	θ value	1.81305 (rank : 172)
Query Neighborhood Hits	244	Target Neighborhood Hits	231	Shared Neighborhood Hits	90
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

LRP6_MOUSE
NC score	0.185008 (rank : 168)	θ value	0.62314 (rank : 144)
Query Neighborhood Hits	244	Target Neighborhood Hits	232	Shared Neighborhood Hits	114
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_HUMAN
NC score	0.184562 (rank : 169)	θ value	1.06291 (rank : 158)
Query Neighborhood Hits	244	Target Neighborhood Hits	235	Shared Neighborhood Hits	116
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

KRA57_HUMAN
NC score	0.184063 (rank : 170)	θ value	6.88961 (rank : 225)
Query Neighborhood Hits	244	Target Neighborhood Hits	269	Shared Neighborhood Hits	104
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

EMR1_MOUSE
NC score	0.182969 (rank : 171)	θ value	8.99809 (rank : 235)
Query Neighborhood Hits	244	Target Neighborhood Hits	349	Shared Neighborhood Hits	141
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

CD97_HUMAN
NC score	0.182893 (rank : 172)	θ value	6.88961 (rank : 221)
Query Neighborhood Hits	244	Target Neighborhood Hits	353	Shared Neighborhood Hits	144
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

KRA47_HUMAN
NC score	0.182820 (rank : 173)	θ value	0.47712 (rank : 138)
Query Neighborhood Hits	244	Target Neighborhood Hits	204	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

SORL_HUMAN
NC score	0.181894 (rank : 174)	θ value	1.38821 (rank : 168)
Query Neighborhood Hits	244	Target Neighborhood Hits	440	Shared Neighborhood Hits	138
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

EMR2_HUMAN
NC score	0.181405 (rank : 175)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	244	Target Neighborhood Hits	345	Shared Neighborhood Hits	140
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

LCE1C_HUMAN
NC score	0.179510 (rank : 176)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	244	Target Neighborhood Hits	65	Shared Neighborhood Hits	33
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

ZP3_HUMAN
NC score	0.179437 (rank : 177)	θ value	0.00175202 (rank : 46)
Query Neighborhood Hits	244	Target Neighborhood Hits	22	Shared Neighborhood Hits	17
SwissProt Accessions	P21754, Q06633	Gene names	ZP3, ZP3A, ZPC
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 precursor (Zona pellucida glycoprotein ZP3) (Zona pellucida protein C) (Sperm receptor) (ZP3A/ZP3B).

WIF1_HUMAN
NC score	0.179114 (rank : 178)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	244	Target Neighborhood Hits	392	Shared Neighborhood Hits	159
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

TSP1_HUMAN
NC score	0.176823 (rank : 179)	θ value	4.03905 (rank : 207)
Query Neighborhood Hits	244	Target Neighborhood Hits	389	Shared Neighborhood Hits	147
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

COMP_MOUSE
NC score	0.174333 (rank : 180)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	244	Target Neighborhood Hits	290	Shared Neighborhood Hits	132
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

KRA92_HUMAN
NC score	0.174072 (rank : 181)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	244	Target Neighborhood Hits	198	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

TSP1_MOUSE
NC score	0.173708 (rank : 182)	θ value	4.03905 (rank : 208)
Query Neighborhood Hits	244	Target Neighborhood Hits	396	Shared Neighborhood Hits	149
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

NAGPA_HUMAN
NC score	0.172837 (rank : 183)	θ value	0.0252991 (rank : 73)
Query Neighborhood Hits	244	Target Neighborhood Hits	282	Shared Neighborhood Hits	120
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

WIF1_MOUSE
NC score	0.172764 (rank : 184)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	244	Target Neighborhood Hits	393	Shared Neighborhood Hits	151
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

NAGPA_MOUSE
NC score	0.172437 (rank : 185)	θ value	0.0563607 (rank : 87)
Query Neighborhood Hits	244	Target Neighborhood Hits	308	Shared Neighborhood Hits	137
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

TENA_HUMAN
NC score	0.172226 (rank : 186)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	244	Target Neighborhood Hits	631	Shared Neighborhood Hits	180
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

EGFL7_MOUSE
NC score	0.171091 (rank : 187)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	244	Target Neighborhood Hits	287	Shared Neighborhood Hits	142
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

KRA93_HUMAN
NC score	0.170445 (rank : 188)	θ value	3.0926 (rank : 191)
Query Neighborhood Hits	244	Target Neighborhood Hits	203	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

HMCN1_HUMAN
NC score	0.170077 (rank : 189)	θ value	0.0736092 (rank : 94)
Query Neighborhood Hits	244	Target Neighborhood Hits	983	Shared Neighborhood Hits	183
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

EGFL8_HUMAN
NC score	0.169032 (rank : 190)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	244	Target Neighborhood Hits	270	Shared Neighborhood Hits	137
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

KRA98_HUMAN
NC score	0.167852 (rank : 191)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	244	Target Neighborhood Hits	185	Shared Neighborhood Hits	89
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

EGFL8_MOUSE
NC score	0.166451 (rank : 192)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	244	Target Neighborhood Hits	266	Shared Neighborhood Hits	135
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

COMP_HUMAN
NC score	0.165286 (rank : 193)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	244	Target Neighborhood Hits	258	Shared Neighborhood Hits	126
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

KR414_HUMAN
NC score	0.165021 (rank : 194)	θ value	1.38821 (rank : 165)
Query Neighborhood Hits	244	Target Neighborhood Hits	199	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KRA56_HUMAN
NC score	0.164356 (rank : 195)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	244	Target Neighborhood Hits	207	Shared Neighborhood Hits	80
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KR10A_HUMAN
NC score	0.163326 (rank : 196)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	244	Target Neighborhood Hits	232	Shared Neighborhood Hits	109
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

KRA54_HUMAN
NC score	0.162921 (rank : 197)	θ value	8.99809 (rank : 240)
Query Neighborhood Hits	244	Target Neighborhood Hits	270	Shared Neighborhood Hits	98
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

TENX_HUMAN
NC score	0.162604 (rank : 198)	θ value	0.125558 (rank : 103)
Query Neighborhood Hits	244	Target Neighborhood Hits	789	Shared Neighborhood Hits	175
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TSP4_MOUSE
NC score	0.162404 (rank : 199)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	244	Target Neighborhood Hits	276	Shared Neighborhood Hits	136
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

TENA_MOUSE
NC score	0.161887 (rank : 200)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	244	Target Neighborhood Hits	596	Shared Neighborhood Hits	174
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

MATN1_HUMAN
NC score	0.161777 (rank : 201)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	244	Target Neighborhood Hits	191	Shared Neighborhood Hits	107
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

KR412_HUMAN
NC score	0.161729 (rank : 202)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	244	Target Neighborhood Hits	178	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

SLIT1_HUMAN
NC score	0.161453 (rank : 203)	θ value	0.0431538 (rank : 83)
Query Neighborhood Hits	244	Target Neighborhood Hits	700	Shared Neighborhood Hits	175
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

KRA45_HUMAN
NC score	0.161241 (rank : 204)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	244	Target Neighborhood Hits	194	Shared Neighborhood Hits	95
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

CD97_MOUSE
NC score	0.161208 (rank : 205)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	244	Target Neighborhood Hits	295	Shared Neighborhood Hits	125
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

MATN1_MOUSE
NC score	0.160887 (rank : 206)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	244	Target Neighborhood Hits	186	Shared Neighborhood Hits	103
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

TGBR3_MOUSE
NC score	0.160119 (rank : 207)	θ value	0.21417 (rank : 118)
Query Neighborhood Hits	244	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	O88393, Q6NS72	Gene names	Tgfbr3
Domain Architecture	No domain graphic available
Description	TGF-beta receptor type III precursor (TGFR-3) (Transforming growth factor beta receptor III) (Betaglycan).

CRDL1_MOUSE
NC score	0.159740 (rank : 208)	θ value	0.0252991 (rank : 72)
Query Neighborhood Hits	244	Target Neighborhood Hits	81	Shared Neighborhood Hits	40
SwissProt Accessions	Q920C1, Q924K0, Q9EPZ9	Gene names	Chrdl1, Ng1, Nrln1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

KRA55_HUMAN
NC score	0.159608 (rank : 209)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	244	Target Neighborhood Hits	257	Shared Neighborhood Hits	97
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

ELTD1_MOUSE
NC score	0.158878 (rank : 210)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	244	Target Neighborhood Hits	288	Shared Neighborhood Hits	122
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

TSP4_HUMAN
NC score	0.158121 (rank : 211)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	244	Target Neighborhood Hits	277	Shared Neighborhood Hits	130
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

KRA52_HUMAN
NC score	0.157433 (rank : 212)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	244	Target Neighborhood Hits	236	Shared Neighborhood Hits	86
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KR103_HUMAN
NC score	0.155768 (rank : 213)	θ value	6.88961 (rank : 223)
Query Neighborhood Hits	244	Target Neighborhood Hits	212	Shared Neighborhood Hits	100
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

TSP2_MOUSE
NC score	0.155135 (rank : 214)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	244	Target Neighborhood Hits	352	Shared Neighborhood Hits	137
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP2_HUMAN
NC score	0.154802 (rank : 215)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	244	Target Neighborhood Hits	359	Shared Neighborhood Hits	143
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

KRA51_HUMAN
NC score	0.153911 (rank : 216)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	244	Target Neighborhood Hits	288	Shared Neighborhood Hits	105
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

LCE3B_HUMAN
NC score	0.152531 (rank : 217)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	244	Target Neighborhood Hits	47	Shared Neighborhood Hits	27
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

PROZ_HUMAN
NC score	0.151758 (rank : 218)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	244	Target Neighborhood Hits	422	Shared Neighborhood Hits	142
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

TLL2_MOUSE
NC score	0.151280 (rank : 219)	θ value	0.0961366 (rank : 99)
Query Neighborhood Hits	244	Target Neighborhood Hits	240	Shared Neighborhood Hits	122
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

PROZ_MOUSE
NC score	0.151234 (rank : 220)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	244	Target Neighborhood Hits	410	Shared Neighborhood Hits	138
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

RECK_HUMAN
NC score	0.150994 (rank : 221)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	244	Target Neighborhood Hits	189	Shared Neighborhood Hits	90
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

TSP3_MOUSE
NC score	0.150885 (rank : 222)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	244	Target Neighborhood Hits	247	Shared Neighborhood Hits	126
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_HUMAN
NC score	0.150832 (rank : 223)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	244	Target Neighborhood Hits	250	Shared Neighborhood Hits	120
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

BMP1_MOUSE
NC score	0.147563 (rank : 224)	θ value	0.365318 (rank : 131)
Query Neighborhood Hits	244	Target Neighborhood Hits	236	Shared Neighborhood Hits	121
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

TLL2_HUMAN
NC score	0.147400 (rank : 225)	θ value	0.62314 (rank : 147)
Query Neighborhood Hits	244	Target Neighborhood Hits	241	Shared Neighborhood Hits	122
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

BMP1_HUMAN
NC score	0.147075 (rank : 226)	θ value	0.365318 (rank : 130)
Query Neighborhood Hits	244	Target Neighborhood Hits	233	Shared Neighborhood Hits	120
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

TLL1_MOUSE
NC score	0.146605 (rank : 227)	θ value	0.62314 (rank : 146)
Query Neighborhood Hits	244	Target Neighborhood Hits	237	Shared Neighborhood Hits	121
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

SLIT1_MOUSE
NC score	0.145881 (rank : 228)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	244	Target Neighborhood Hits	715	Shared Neighborhood Hits	178
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

TLL1_HUMAN
NC score	0.145222 (rank : 229)	θ value	0.62314 (rank : 145)
Query Neighborhood Hits	244	Target Neighborhood Hits	236	Shared Neighborhood Hits	119
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

LAMA1_MOUSE
NC score	0.145204 (rank : 230)	θ value	0.0193708 (rank : 68)
Query Neighborhood Hits	244	Target Neighborhood Hits	838	Shared Neighborhood Hits	166
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

KR171_HUMAN
NC score	0.145097 (rank : 231)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	244	Target Neighborhood Hits	144	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KRA15_HUMAN
NC score	0.145062 (rank : 232)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	244	Target Neighborhood Hits	126	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KRA11_HUMAN
NC score	0.143796 (rank : 233)	θ value	8.99809 (rank : 239)
Query Neighborhood Hits	244	Target Neighborhood Hits	155	Shared Neighborhood Hits	80
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

SLIT3_MOUSE
NC score	0.143594 (rank : 234)	θ value	0.0431538 (rank : 84)
Query Neighborhood Hits	244	Target Neighborhood Hits	700	Shared Neighborhood Hits	170
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

CRDL2_MOUSE
NC score	0.143036 (rank : 235)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	244	Target Neighborhood Hits	81	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

KRA44_HUMAN
NC score	0.142998 (rank : 236)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	244	Target Neighborhood Hits	162	Shared Neighborhood Hits	80
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

SLIT2_HUMAN
NC score	0.142670 (rank : 237)	θ value	8.99809 (rank : 243)
Query Neighborhood Hits	244	Target Neighborhood Hits	708	Shared Neighborhood Hits	179
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

KRA99_HUMAN
NC score	0.142467 (rank : 238)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	244	Target Neighborhood Hits	173	Shared Neighborhood Hits	89
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

MCSP_MOUSE
NC score	0.141885 (rank : 239)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	244	Target Neighborhood Hits	108	Shared Neighborhood Hits	34
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

RECK_MOUSE
NC score	0.141860 (rank : 240)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	244	Target Neighborhood Hits	158	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

PCSK5_HUMAN
NC score	0.141445 (rank : 241)	θ value	0.00665767 (rank : 57)
Query Neighborhood Hits	244	Target Neighborhood Hits	291	Shared Neighborhood Hits	121
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

LCE1B_HUMAN
NC score	0.140436 (rank : 242)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	244	Target Neighborhood Hits	58	Shared Neighborhood Hits	32
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

KR410_HUMAN
NC score	0.139670 (rank : 243)	θ value	2.36792 (rank : 179)
Query Neighborhood Hits	244	Target Neighborhood Hits	156	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

CRDL2_HUMAN
NC score	0.139597 (rank : 244)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	244	Target Neighborhood Hits	99	Shared Neighborhood Hits	38
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

LAMA5_HUMAN
NC score	0.139377 (rank : 245)	θ value	5.27518 (rank : 214)
Query Neighborhood Hits	244	Target Neighborhood Hits	976	Shared Neighborhood Hits	176
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

SLIT2_MOUSE
NC score	0.138759 (rank : 246)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	244	Target Neighborhood Hits	684	Shared Neighborhood Hits	167
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

PCSK6_HUMAN
NC score	0.137668 (rank : 247)	θ value	0.000602161 (rank : 39)
Query Neighborhood Hits	244	Target Neighborhood Hits	298	Shared Neighborhood Hits	106
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

LAMA5_MOUSE
NC score	0.137564 (rank : 248)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	244	Target Neighborhood Hits	828	Shared Neighborhood Hits	174
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

SLIT3_HUMAN
NC score	0.136482 (rank : 249)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	244	Target Neighborhood Hits	682	Shared Neighborhood Hits	163
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

LCE5A_HUMAN
NC score	0.135560 (rank : 250)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	244	Target Neighborhood Hits	43	Shared Neighborhood Hits	15
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

MEGF9_MOUSE
NC score	0.134426 (rank : 251)	θ value	3.0926 (rank : 192)
Query Neighborhood Hits	244	Target Neighborhood Hits	896	Shared Neighborhood Hits	135
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MT4_MOUSE
NC score	0.133853 (rank : 252)	θ value	2.36792 (rank : 183)
Query Neighborhood Hits	244	Target Neighborhood Hits	102	Shared Neighborhood Hits	38
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

KR510_HUMAN
NC score	0.131824 (rank : 253)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	244	Target Neighborhood Hits	217	Shared Neighborhood Hits	76
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

EDIL3_MOUSE
NC score	0.131509 (rank : 254)	θ value	4.03905 (rank : 199)
Query Neighborhood Hits	244	Target Neighborhood Hits	317	Shared Neighborhood Hits	124
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

LCE2A_HUMAN
NC score	0.130407 (rank : 255)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	244	Target Neighborhood Hits	50	Shared Neighborhood Hits	21
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

NFX1_HUMAN
NC score	0.129621 (rank : 256)	θ value	6.88961 (rank : 229)
Query Neighborhood Hits	244	Target Neighborhood Hits	405	Shared Neighborhood Hits	116
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

LAMA1_HUMAN
NC score	0.128013 (rank : 257)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	244	Target Neighborhood Hits	804	Shared Neighborhood Hits	159
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

EDIL3_HUMAN
NC score	0.126991 (rank : 258)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	244	Target Neighborhood Hits	292	Shared Neighborhood Hits	124
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

CHRD_HUMAN
NC score	0.125433 (rank : 259)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	244	Target Neighborhood Hits	102	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

MEGF9_HUMAN
NC score	0.125393 (rank : 260)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	244	Target Neighborhood Hits	557	Shared Neighborhood Hits	142
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

CSPG2_MOUSE
NC score	0.123648 (rank : 261)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	244	Target Neighborhood Hits	711	Shared Neighborhood Hits	126
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

NOV_HUMAN
NC score	0.123323 (rank : 262)	θ value	0.21417 (rank : 117)
Query Neighborhood Hits	244	Target Neighborhood Hits	128	Shared Neighborhood Hits	51
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

LAMC3_HUMAN
NC score	0.122099 (rank : 263)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	244	Target Neighborhood Hits	588	Shared Neighborhood Hits	158
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LYAM3_MOUSE
NC score	0.122074 (rank : 264)	θ value	6.88961 (rank : 228)
Query Neighborhood Hits	244	Target Neighborhood Hits	390	Shared Neighborhood Hits	136
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

CSPG2_HUMAN
NC score	0.120336 (rank : 265)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	244	Target Neighborhood Hits	681	Shared Neighborhood Hits	122
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

LCE2C_HUMAN
NC score	0.119304 (rank : 266)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	244	Target Neighborhood Hits	53	Shared Neighborhood Hits	22
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LAMB2_HUMAN
NC score	0.117660 (rank : 267)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	244	Target Neighborhood Hits	692	Shared Neighborhood Hits	149
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

CHRD_MOUSE
NC score	0.117058 (rank : 268)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	244	Target Neighborhood Hits	102	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

LAMB2_MOUSE
NC score	0.115718 (rank : 269)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	244	Target Neighborhood Hits	722	Shared Neighborhood Hits	152
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMC3_MOUSE
NC score	0.115654 (rank : 270)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	244	Target Neighborhood Hits	624	Shared Neighborhood Hits	151
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

CRDL1_HUMAN
NC score	0.115278 (rank : 271)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	244	Target Neighborhood Hits	75	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BU40, Q9Y3H7	Gene names	CHRDL1, NRLN1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

WISP2_MOUSE
NC score	0.115066 (rank : 272)	θ value	5.27518 (rank : 219)
Query Neighborhood Hits	244	Target Neighborhood Hits	129	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

WISP1_MOUSE
NC score	0.114377 (rank : 273)	θ value	0.62314 (rank : 148)
Query Neighborhood Hits	244	Target Neighborhood Hits	123	Shared Neighborhood Hits	42
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

LAMA2_HUMAN
NC score	0.113398 (rank : 274)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	244	Target Neighborhood Hits	1092	Shared Neighborhood Hits	159
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

CRAC1_MOUSE
NC score	0.111155 (rank : 275)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	244	Target Neighborhood Hits	112	Shared Neighborhood Hits	77
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

PERT_HUMAN
NC score	0.111084 (rank : 276)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	244	Target Neighborhood Hits	221	Shared Neighborhood Hits	116
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

LAMA2_MOUSE
NC score	0.110412 (rank : 277)	θ value	1.06291 (rank : 157)
Query Neighborhood Hits	244	Target Neighborhood Hits	1198	Shared Neighborhood Hits	158
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

TGBR3_HUMAN
NC score	0.109369 (rank : 278)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	244	Target Neighborhood Hits	44	Shared Neighborhood Hits	13
SwissProt Accessions	Q03167, Q5T2T4, Q5U731, Q9UGI2	Gene names	TGFBR3
Domain Architecture
Description	TGF-beta receptor type III precursor (TGFR-3) (Transforming growth factor beta receptor III) (Betaglycan).

CRAC1_HUMAN
NC score	0.109346 (rank : 279)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	244	Target Neighborhood Hits	111	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

LAMC1_MOUSE
NC score	0.108733 (rank : 280)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	244	Target Neighborhood Hits	856	Shared Neighborhood Hits	146
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

KRA42_HUMAN
NC score	0.107484 (rank : 281)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	244	Target Neighborhood Hits	149	Shared Neighborhood Hits	74
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

LAMB1_MOUSE
NC score	0.106863 (rank : 282)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	244	Target Neighborhood Hits	919	Shared Neighborhood Hits	148
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LRP3_HUMAN
NC score	0.106626 (rank : 283)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	244	Target Neighborhood Hits	280	Shared Neighborhood Hits	82
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

ELTD1_HUMAN
NC score	0.106447 (rank : 284)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	244	Target Neighborhood Hits	269	Shared Neighborhood Hits	115
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

LAMC1_HUMAN
NC score	0.106205 (rank : 285)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	244	Target Neighborhood Hits	922	Shared Neighborhood Hits	148
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LCE2D_HUMAN
NC score	0.105710 (rank : 286)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	244	Target Neighborhood Hits	50	Shared Neighborhood Hits	19
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

CSPG3_HUMAN
NC score	0.105642 (rank : 287)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	244	Target Neighborhood Hits	676	Shared Neighborhood Hits	118
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

PGBM_MOUSE
NC score	0.105386 (rank : 288)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	244	Target Neighborhood Hits	1073	Shared Neighborhood Hits	168
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

LAMC2_MOUSE
NC score	0.105184 (rank : 289)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	244	Target Neighborhood Hits	614	Shared Neighborhood Hits	145
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

ITB6_MOUSE
NC score	0.104727 (rank : 290)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	244	Target Neighborhood Hits	341	Shared Neighborhood Hits	135
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB5_MOUSE
NC score	0.104260 (rank : 291)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	244	Target Neighborhood Hits	329	Shared Neighborhood Hits	138
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

PERT_MOUSE
NC score	0.104038 (rank : 292)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	244	Target Neighborhood Hits	221	Shared Neighborhood Hits	111
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

WISP2_HUMAN
NC score	0.103724 (rank : 293)	θ value	2.36792 (rank : 184)
Query Neighborhood Hits	244	Target Neighborhood Hits	126	Shared Neighborhood Hits	45
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

TENR_MOUSE
NC score	0.103518 (rank : 294)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	244	Target Neighborhood Hits	531	Shared Neighborhood Hits	153
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

LRP12_HUMAN
NC score	0.102995 (rank : 295)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	244	Target Neighborhood Hits	205	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

USH2A_MOUSE
NC score	0.102307 (rank : 296)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	244	Target Neighborhood Hits	626	Shared Neighborhood Hits	150
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

CSPG3_MOUSE
NC score	0.102293 (rank : 297)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	244	Target Neighborhood Hits	657	Shared Neighborhood Hits	120
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

LYAM3_HUMAN
NC score	0.102060 (rank : 298)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	244	Target Neighborhood Hits	378	Shared Neighborhood Hits	134
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LCE2B_HUMAN
NC score	0.102056 (rank : 299)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	244	Target Neighborhood Hits	50	Shared Neighborhood Hits	16
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

LAMA3_MOUSE
NC score	0.101648 (rank : 300)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	244	Target Neighborhood Hits	859	Shared Neighborhood Hits	154
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

KR413_HUMAN
NC score	0.101616 (rank : 301)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	244	Target Neighborhood Hits	112	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

PGBM_HUMAN
NC score	0.101222 (rank : 302)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	244	Target Neighborhood Hits	1113	Shared Neighborhood Hits	156
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

LRP12_MOUSE
NC score	0.100702 (rank : 303)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	244	Target Neighborhood Hits	180	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

ZNFX1_HUMAN
NC score	0.100473 (rank : 304)	θ value	6.88961 (rank : 232)
Query Neighborhood Hits	244	Target Neighborhood Hits	308	Shared Neighborhood Hits	82
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

LAMB1_HUMAN
NC score	0.100292 (rank : 305)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	244	Target Neighborhood Hits	1018	Shared Neighborhood Hits	156
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

TENR_HUMAN
NC score	0.100260 (rank : 306)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	244	Target Neighborhood Hits	526	Shared Neighborhood Hits	152
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

WISP1_HUMAN
NC score	0.099972 (rank : 307)	θ value	5.27518 (rank : 218)
Query Neighborhood Hits	244	Target Neighborhood Hits	121	Shared Neighborhood Hits	42
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

ATRN_MOUSE
NC score	0.099831 (rank : 308)	θ value	3.0926 (rank : 187)
Query Neighborhood Hits	244	Target Neighborhood Hits	519	Shared Neighborhood Hits	134
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

ITB3_HUMAN
NC score	0.097476 (rank : 309)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	244	Target Neighborhood Hits	325	Shared Neighborhood Hits	141
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ZNFX1_MOUSE
NC score	0.096813 (rank : 310)	θ value	6.88961 (rank : 233)
Query Neighborhood Hits	244	Target Neighborhood Hits	407	Shared Neighborhood Hits	80
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

CD320_HUMAN
NC score	0.096760 (rank : 311)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	244	Target Neighborhood Hits	103	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

ITB2_MOUSE
NC score	0.096533 (rank : 312)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	244	Target Neighborhood Hits	326	Shared Neighborhood Hits	138
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB3_MOUSE
NC score	0.096263 (rank : 313)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	244	Target Neighborhood Hits	319	Shared Neighborhood Hits	133
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

NOV_MOUSE
NC score	0.095997 (rank : 314)	θ value	5.27518 (rank : 216)
Query Neighborhood Hits	244	Target Neighborhood Hits	130	Shared Neighborhood Hits	50
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

LAMC2_HUMAN
NC score	0.095740 (rank : 315)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	244	Target Neighborhood Hits	715	Shared Neighborhood Hits	135
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

MT4_HUMAN
NC score	0.095484 (rank : 316)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	244	Target Neighborhood Hits	83	Shared Neighborhood Hits	27
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

LCE1D_HUMAN
NC score	0.095319 (rank : 317)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	244	Target Neighborhood Hits	44	Shared Neighborhood Hits	24
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

ITB5_HUMAN
NC score	0.094624 (rank : 318)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	244	Target Neighborhood Hits	310	Shared Neighborhood Hits	135
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ATRN_HUMAN
NC score	0.094615 (rank : 319)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	244	Target Neighborhood Hits	525	Shared Neighborhood Hits	134
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

MFGM_MOUSE
NC score	0.094556 (rank : 320)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	244	Target Neighborhood Hits	233	Shared Neighborhood Hits	89
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

PHXR5_MOUSE
NC score	0.094049 (rank : 321)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	244	Target Neighborhood Hits	102	Shared Neighborhood Hits	66
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

SPR2I_MOUSE
NC score	0.093985 (rank : 322)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	244	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

ITB6_HUMAN
NC score	0.093717 (rank : 323)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	244	Target Neighborhood Hits	318	Shared Neighborhood Hits	126
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

SPR2E_MOUSE
NC score	0.093708 (rank : 324)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	244	Target Neighborhood Hits	45	Shared Neighborhood Hits	16
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

FATH_HUMAN
NC score	0.093171 (rank : 325)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	244	Target Neighborhood Hits	570	Shared Neighborhood Hits	150
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

FA10_MOUSE
NC score	0.093101 (rank : 326)	θ value	0.0736092 (rank : 92)
Query Neighborhood Hits	244	Target Neighborhood Hits	435	Shared Neighborhood Hits	143
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

USH2A_HUMAN
NC score	0.092772 (rank : 327)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	244	Target Neighborhood Hits	600	Shared Neighborhood Hits	133
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

LCE4A_HUMAN
NC score	0.092531 (rank : 328)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	244	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

FA10_HUMAN
NC score	0.091999 (rank : 329)	θ value	0.279714 (rank : 122)
Query Neighborhood Hits	244	Target Neighborhood Hits	431	Shared Neighborhood Hits	139
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

LAMB3_MOUSE
NC score	0.091536 (rank : 330)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	244	Target Neighborhood Hits	444	Shared Neighborhood Hits	125
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

SPR2D_MOUSE
NC score	0.091532 (rank : 331)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	244	Target Neighborhood Hits	61	Shared Neighborhood Hits	19
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

TNR25_HUMAN
NC score	0.091400 (rank : 332)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	244	Target Neighborhood Hits	172	Shared Neighborhood Hits	54
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

WFDC3_HUMAN
NC score	0.091284 (rank : 333)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	244	Target Neighborhood Hits	138	Shared Neighborhood Hits	70
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

LYAM2_HUMAN
NC score	0.091083 (rank : 334)	θ value	1.81305 (rank : 174)
Query Neighborhood Hits	244	Target Neighborhood Hits	394	Shared Neighborhood Hits	130
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

EMR3_HUMAN
NC score	0.090574 (rank : 335)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	244	Target Neighborhood Hits	245	Shared Neighborhood Hits	104
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

CYR61_MOUSE
NC score	0.089784 (rank : 336)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	244	Target Neighborhood Hits	156	Shared Neighborhood Hits	52
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

CK024_MOUSE
NC score	0.089459 (rank : 337)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	244	Target Neighborhood Hits	307	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

CTGF_HUMAN
NC score	0.089171 (rank : 338)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	244	Target Neighborhood Hits	128	Shared Neighborhood Hits	49
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

ITB7_HUMAN
NC score	0.088860 (rank : 339)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	244	Target Neighborhood Hits	290	Shared Neighborhood Hits	125
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

CLC14_MOUSE
NC score	0.088670 (rank : 340)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	244	Target Neighborhood Hits	120	Shared Neighborhood Hits	85
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

NTNG2_MOUSE
NC score	0.088592 (rank : 341)	θ value	3.0926 (rank : 193)
Query Neighborhood Hits	244	Target Neighborhood Hits	276	Shared Neighborhood Hits	106
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

LYAM2_MOUSE
NC score	0.088561 (rank : 342)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	244	Target Neighborhood Hits	420	Shared Neighborhood Hits	137
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

VEGFC_HUMAN
NC score	0.088542 (rank : 343)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	244	Target Neighborhood Hits	128	Shared Neighborhood Hits	59
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

HHIP_HUMAN
NC score	0.088516 (rank : 344)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	244	Target Neighborhood Hits	249	Shared Neighborhood Hits	103
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

ITB1_HUMAN
NC score	0.088153 (rank : 345)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	244	Target Neighborhood Hits	298	Shared Neighborhood Hits	118
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

TNR9_HUMAN
NC score	0.088151 (rank : 346)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	244	Target Neighborhood Hits	166	Shared Neighborhood Hits	52
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

CTGF_MOUSE
NC score	0.087908 (rank : 347)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	244	Target Neighborhood Hits	124	Shared Neighborhood Hits	47
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

NTNG2_HUMAN
NC score	0.087633 (rank : 348)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	244	Target Neighborhood Hits	276	Shared Neighborhood Hits	103
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

TNR8_HUMAN
NC score	0.087201 (rank : 349)	θ value	3.0926 (rank : 196)
Query Neighborhood Hits	244	Target Neighborhood Hits	198	Shared Neighborhood Hits	55
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

CYR61_HUMAN
NC score	0.086880 (rank : 350)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	244	Target Neighborhood Hits	159	Shared Neighborhood Hits	53
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

CLC14_HUMAN
NC score	0.086092 (rank : 351)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	244	Target Neighborhood Hits	143	Shared Neighborhood Hits	89
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

FST_HUMAN
NC score	0.085190 (rank : 352)	θ value	1.06291 (rank : 155)
Query Neighborhood Hits	244	Target Neighborhood Hits	129	Shared Neighborhood Hits	48
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

TNR16_MOUSE
NC score	0.085080 (rank : 353)	θ value	0.0961366 (rank : 100)
Query Neighborhood Hits	244	Target Neighborhood Hits	178	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

ST14_MOUSE
NC score	0.084991 (rank : 354)	θ value	8.99809 (rank : 244)
Query Neighborhood Hits	244	Target Neighborhood Hits	419	Shared Neighborhood Hits	125
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

ITB7_MOUSE
NC score	0.084583 (rank : 355)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	244	Target Neighborhood Hits	277	Shared Neighborhood Hits	115
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

C1RA_MOUSE
NC score	0.083534 (rank : 356)	θ value	0.0736092 (rank : 90)
Query Neighborhood Hits	244	Target Neighborhood Hits	379	Shared Neighborhood Hits	115
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

ITB2_HUMAN
NC score	0.083373 (rank : 357)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	244	Target Neighborhood Hits	282	Shared Neighborhood Hits	123
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

FST_MOUSE
NC score	0.083021 (rank : 358)	θ value	4.03905 (rank : 200)
Query Neighborhood Hits	244	Target Neighborhood Hits	146	Shared Neighborhood Hits	64
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

LAMA3_HUMAN
NC score	0.082629 (rank : 359)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	244	Target Neighborhood Hits	760	Shared Neighborhood Hits	122
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

MFRP_HUMAN
NC score	0.082606 (rank : 360)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	244	Target Neighborhood Hits	165	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

C1RB_MOUSE
NC score	0.082503 (rank : 361)	θ value	0.0736092 (rank : 91)
Query Neighborhood Hits	244	Target Neighborhood Hits	380	Shared Neighborhood Hits	115
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

MAMC2_MOUSE
NC score	0.082389 (rank : 362)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	244	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

ITB1_MOUSE
NC score	0.081971 (rank : 363)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	244	Target Neighborhood Hits	283	Shared Neighborhood Hits	114
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

SPR2F_MOUSE
NC score	0.081516 (rank : 364)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	244	Target Neighborhood Hits	43	Shared Neighborhood Hits	12
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

CELR2_HUMAN
NC score	0.081081 (rank : 365)	θ value	5.27518 (rank : 209)
Query Neighborhood Hits	244	Target Neighborhood Hits	657	Shared Neighborhood Hits	163
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

KRA24_HUMAN
NC score	0.080454 (rank : 366)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	244	Target Neighborhood Hits	192	Shared Neighborhood Hits	73
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

MAMC2_HUMAN
NC score	0.080272 (rank : 367)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	244	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

ST14_HUMAN
NC score	0.080092 (rank : 368)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	244	Target Neighborhood Hits	409	Shared Neighborhood Hits	118
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

HHIP_MOUSE
NC score	0.079745 (rank : 369)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	244	Target Neighborhood Hits	219	Shared Neighborhood Hits	84
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

ITB4_HUMAN
NC score	0.079605 (rank : 370)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	244	Target Neighborhood Hits	458	Shared Neighborhood Hits	116
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

PROC_MOUSE
NC score	0.078487 (rank : 371)	θ value	8.99809 (rank : 242)
Query Neighborhood Hits	244	Target Neighborhood Hits	426	Shared Neighborhood Hits	142
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

CELR3_MOUSE
NC score	0.078121 (rank : 372)	θ value	3.0926 (rank : 188)
Query Neighborhood Hits	244	Target Neighborhood Hits	687	Shared Neighborhood Hits	154
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

CELR3_HUMAN
NC score	0.077570 (rank : 373)	θ value	5.27518 (rank : 210)
Query Neighborhood Hits	244	Target Neighborhood Hits	680	Shared Neighborhood Hits	150
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

MDC1_HUMAN
NC score	0.077233 (rank : 374)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	244	Target Neighborhood Hits	1446	Shared Neighborhood Hits	13
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

C1R_HUMAN
NC score	0.077108 (rank : 375)	θ value	0.279714 (rank : 120)
Query Neighborhood Hits	244	Target Neighborhood Hits	364	Shared Neighborhood Hits	112
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

ASTN_HUMAN
NC score	0.076708 (rank : 376)	θ value	4.03905 (rank : 198)
Query Neighborhood Hits	244	Target Neighborhood Hits	105	Shared Neighborhood Hits	76
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

LAMB3_HUMAN
NC score	0.076164 (rank : 377)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	244	Target Neighborhood Hits	461	Shared Neighborhood Hits	103
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

CORIN_MOUSE
NC score	0.075824 (rank : 378)	θ value	0.47712 (rank : 137)
Query Neighborhood Hits	244	Target Neighborhood Hits	451	Shared Neighborhood Hits	119
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

CORIN_HUMAN
NC score	0.075760 (rank : 379)	θ value	6.88961 (rank : 222)
Query Neighborhood Hits	244	Target Neighborhood Hits	453	Shared Neighborhood Hits	125
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

GP112_HUMAN
NC score	0.075619 (rank : 380)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	244	Target Neighborhood Hits	441	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

TENN_MOUSE
NC score	0.075554 (rank : 381)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	244	Target Neighborhood Hits	484	Shared Neighborhood Hits	136
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

LRP10_MOUSE
NC score	0.074532 (rank : 382)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	244	Target Neighborhood Hits	169	Shared Neighborhood Hits	50
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

TNR8_MOUSE
NC score	0.073750 (rank : 383)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	244	Target Neighborhood Hits	208	Shared Neighborhood Hits	55
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

FA9_HUMAN
NC score	0.073716 (rank : 384)	θ value	5.27518 (rank : 211)
Query Neighborhood Hits	244	Target Neighborhood Hits	421	Shared Neighborhood Hits	138
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

LAMA4_MOUSE
NC score	0.073495 (rank : 385)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	244	Target Neighborhood Hits	584	Shared Neighborhood Hits	106
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

TINAG_HUMAN
NC score	0.073256 (rank : 386)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	244	Target Neighborhood Hits	63	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UJW2, Q9UJW1, Q9ULZ4	Gene names	TINAG
Domain Architecture
Description	Tubulointerstitial nephritis antigen (TIN-Ag).

ITB8_HUMAN
NC score	0.072990 (rank : 387)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	244	Target Neighborhood Hits	280	Shared Neighborhood Hits	116
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

COCH_HUMAN
NC score	0.072729 (rank : 388)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	244	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	O43405	Gene names	COCH, COCH5B2
Domain Architecture
Description	Cochlin precursor (COCH-5B2).

NRP2_HUMAN
NC score	0.072577 (rank : 389)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	244	Target Neighborhood Hits	120	Shared Neighborhood Hits	22
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

MFRP_MOUSE
NC score	0.072539 (rank : 390)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	244	Target Neighborhood Hits	166	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

COCH_MOUSE
NC score	0.072534 (rank : 391)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	244	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	Q62507, Q3TAF5, Q9QWK6	Gene names	Coch
Domain Architecture
Description	Cochlin precursor (COCH-5B2).

TNR1A_MOUSE
NC score	0.072346 (rank : 392)	θ value	0.47712 (rank : 141)
Query Neighborhood Hits	244	Target Neighborhood Hits	131	Shared Neighborhood Hits	31
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

CFC1_HUMAN
NC score	0.072159 (rank : 393)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	244	Target Neighborhood Hits	148	Shared Neighborhood Hits	66
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

VITRN_MOUSE
NC score	0.072021 (rank : 394)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	244	Target Neighborhood Hits	68	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VHI5, Q3TZ47, Q8BQ41, Q8K047, Q9CYZ1	Gene names	Vit
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

RSPO4_HUMAN
NC score	0.071099 (rank : 395)	θ value	3.0926 (rank : 194)
Query Neighborhood Hits	244	Target Neighborhood Hits	110	Shared Neighborhood Hits	47
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

ZP3_MOUSE
NC score	0.070969 (rank : 396)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	244	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	P10761	Gene names	Zp3, Zp-3, Zpc
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 precursor (Zona pellucida glycoprotein ZP3) (Sperm receptor) (Zona pellucida protein C).

TNR9_MOUSE
NC score	0.070896 (rank : 397)	θ value	3.0926 (rank : 197)
Query Neighborhood Hits	244	Target Neighborhood Hits	137	Shared Neighborhood Hits	40
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

CELR1_MOUSE
NC score	0.070562 (rank : 398)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	244	Target Neighborhood Hits	617	Shared Neighborhood Hits	145
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

TSG6_MOUSE
NC score	0.070463 (rank : 399)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	244	Target Neighborhood Hits	91	Shared Neighborhood Hits	21
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

TSG6_HUMAN
NC score	0.070371 (rank : 400)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	244	Target Neighborhood Hits	91	Shared Neighborhood Hits	22
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

NRP1_HUMAN
NC score	0.070283 (rank : 401)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	244	Target Neighborhood Hits	119	Shared Neighborhood Hits	22
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

WISP3_HUMAN
NC score	0.070078 (rank : 402)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	244	Target Neighborhood Hits	87	Shared Neighborhood Hits	23
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

CELR1_HUMAN
NC score	0.069851 (rank : 403)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	244	Target Neighborhood Hits	613	Shared Neighborhood Hits	144
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

NACAM_MOUSE
NC score	0.069741 (rank : 404)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	244	Target Neighborhood Hits	1866	Shared Neighborhood Hits	22
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

HABP2_HUMAN
NC score	0.069207 (rank : 405)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	244	Target Neighborhood Hits	431	Shared Neighborhood Hits	116
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

LCE3C_HUMAN
NC score	0.069151 (rank : 406)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	244	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T5A8	Gene names	LCE3C, LEP15, SPRL3A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A).

MT3_HUMAN
NC score	0.069080 (rank : 407)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	244	Target Neighborhood Hits	82	Shared Neighborhood Hits	21
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

PROC_HUMAN
NC score	0.069045 (rank : 408)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	244	Target Neighborhood Hits	406	Shared Neighborhood Hits	134
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

MDC1_MOUSE
NC score	0.068833 (rank : 409)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	244	Target Neighborhood Hits	998	Shared Neighborhood Hits	17
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

CELR2_MOUSE
NC score	0.068382 (rank : 410)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	244	Target Neighborhood Hits	584	Shared Neighborhood Hits	141
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

HG2A_MOUSE
NC score	0.068044 (rank : 411)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	244	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	P04441, O19452	Gene names	Cd74, Ii
Domain Architecture
Description	H-2 class II histocompatibility antigen gamma chain (MHC class II- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD74 antigen).

NTNG1_HUMAN
NC score	0.067800 (rank : 412)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	244	Target Neighborhood Hits	247	Shared Neighborhood Hits	90
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

TEFF2_MOUSE
NC score	0.067784 (rank : 413)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	244	Target Neighborhood Hits	214	Shared Neighborhood Hits	76
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

LAMA4_HUMAN
NC score	0.067559 (rank : 414)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	244	Target Neighborhood Hits	708	Shared Neighborhood Hits	103
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

HABP2_MOUSE
NC score	0.067474 (rank : 415)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	244	Target Neighborhood Hits	445	Shared Neighborhood Hits	121
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

LEUK_HUMAN
NC score	0.067242 (rank : 416)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	244	Target Neighborhood Hits	213	Shared Neighborhood Hits	7
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

LRP10_HUMAN
NC score	0.067096 (rank : 417)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	244	Target Neighborhood Hits	197	Shared Neighborhood Hits	46
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

FSTL1_HUMAN
NC score	0.066879 (rank : 418)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	244	Target Neighborhood Hits	68	Shared Neighborhood Hits	14
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

TEFF2_HUMAN
NC score	0.066378 (rank : 419)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	244	Target Neighborhood Hits	211	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

NTNG1_MOUSE
NC score	0.066357 (rank : 420)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	244	Target Neighborhood Hits	246	Shared Neighborhood Hits	86
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

VITRN_HUMAN
NC score	0.066263 (rank : 421)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	244	Target Neighborhood Hits	63	Shared Neighborhood Hits	9
SwissProt Accessions	Q6UXI7, Q6P7T3, Q96DT1	Gene names	VIT
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

MAP4_HUMAN
NC score	0.066083 (rank : 422)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	244	Target Neighborhood Hits	428	Shared Neighborhood Hits	7
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

NRP1_MOUSE
NC score	0.065918 (rank : 423)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	244	Target Neighborhood Hits	120	Shared Neighborhood Hits	21
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

FSTL3_MOUSE
NC score	0.065552 (rank : 424)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	244	Target Neighborhood Hits	152	Shared Neighborhood Hits	70
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

ASTN_MOUSE
NC score	0.065251 (rank : 425)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	244	Target Neighborhood Hits	98	Shared Neighborhood Hits	72
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

PCOC2_HUMAN
NC score	0.064699 (rank : 426)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	244	Target Neighborhood Hits	73	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

WFDC2_HUMAN
NC score	0.064485 (rank : 427)	θ value	1.81305 (rank : 177)
Query Neighborhood Hits	244	Target Neighborhood Hits	73	Shared Neighborhood Hits	33
SwissProt Accessions	Q14508, Q8WXV9, Q8WXW0, Q8WXW1, Q8WXW2, Q96KJ1	Gene names	WFDC2, HE4, WAP5
Domain Architecture
Description	WAP four-disulfide core domain protein 2 precursor (Major epididymis- specific protein E4) (Epididymal secretory protein E4) (Putative protease inhibitor WAP5).

FA7_HUMAN
NC score	0.064480 (rank : 428)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	244	Target Neighborhood Hits	404	Shared Neighborhood Hits	132
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

FSTL1_MOUSE
NC score	0.064357 (rank : 429)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	244	Target Neighborhood Hits	74	Shared Neighborhood Hits	13
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

TENN_HUMAN
NC score	0.064308 (rank : 430)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	244	Target Neighborhood Hits	453	Shared Neighborhood Hits	134
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

FSTL3_HUMAN
NC score	0.064306 (rank : 431)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	244	Target Neighborhood Hits	162	Shared Neighborhood Hits	66
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

HG2A_HUMAN
NC score	0.063880 (rank : 432)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	244	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	P04233, Q14597, Q29832, Q5U0J8, Q8WLP6	Gene names	CD74, DHLAG
Domain Architecture	No domain graphic available
Description	HLA class II histocompatibility antigen gamma chain (HLA-DR antigens- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (p33) (CD74 antigen).

CO6A3_HUMAN
NC score	0.063653 (rank : 433)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	244	Target Neighborhood Hits	317	Shared Neighborhood Hits	12
SwissProt Accessions	P12111, Q16501	Gene names	COL6A3
Domain Architecture
Description	Collagen alpha-3(VI) chain precursor.

PCOC2_MOUSE
NC score	0.063570 (rank : 434)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	244	Target Neighborhood Hits	73	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

LYAM1_MOUSE
NC score	0.063419 (rank : 435)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	244	Target Neighborhood Hits	332	Shared Neighborhood Hits	101
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

SPR2G_MOUSE
NC score	0.063262 (rank : 436)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	244	Target Neighborhood Hits	53	Shared Neighborhood Hits	18
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

NETO1_HUMAN
NC score	0.063154 (rank : 437)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	244	Target Neighborhood Hits	110	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

MASP2_HUMAN
NC score	0.063078 (rank : 438)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	244	Target Neighborhood Hits	364	Shared Neighborhood Hits	108
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

NETO2_HUMAN
NC score	0.063010 (rank : 439)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	244	Target Neighborhood Hits	109	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

TDGF1_MOUSE
NC score	0.062926 (rank : 440)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	244	Target Neighborhood Hits	146	Shared Neighborhood Hits	65
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

PCOC1_MOUSE
NC score	0.062612 (rank : 441)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	244	Target Neighborhood Hits	100	Shared Neighborhood Hits	18
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC1_HUMAN
NC score	0.062431 (rank : 442)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	244	Target Neighborhood Hits	146	Shared Neighborhood Hits	17
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

NETO2_MOUSE
NC score	0.062419 (rank : 443)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	244	Target Neighborhood Hits	113	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO1_MOUSE
NC score	0.062186 (rank : 444)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	244	Target Neighborhood Hits	109	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

MAP4_MOUSE
NC score	0.062068 (rank : 445)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	244	Target Neighborhood Hits	409	Shared Neighborhood Hits	7
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

LYAM1_HUMAN
NC score	0.062003 (rank : 446)	θ value	6.88961 (rank : 227)
Query Neighborhood Hits	244	Target Neighborhood Hits	315	Shared Neighborhood Hits	100
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

MASP2_MOUSE
NC score	0.061899 (rank : 447)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	244	Target Neighborhood Hits	382	Shared Neighborhood Hits	110
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

NRP2_MOUSE
NC score	0.061808 (rank : 448)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	244	Target Neighborhood Hits	113	Shared Neighborhood Hits	22
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

RSPO3_HUMAN
NC score	0.061688 (rank : 449)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	244	Target Neighborhood Hits	128	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

CS1A_MOUSE
NC score	0.061440 (rank : 450)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	244	Target Neighborhood Hits	360	Shared Neighborhood Hits	109
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

SPR2H_MOUSE
NC score	0.061432 (rank : 451)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	244	Target Neighborhood Hits	82	Shared Neighborhood Hits	18
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

CS1B_MOUSE
NC score	0.061261 (rank : 452)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	244	Target Neighborhood Hits	361	Shared Neighborhood Hits	109
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

PGCB_MOUSE
NC score	0.061173 (rank : 453)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	244	Target Neighborhood Hits	459	Shared Neighborhood Hits	89
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

CER1_HUMAN
NC score	0.060809 (rank : 454)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	244	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	O95813, Q6ISJ1, Q6ISJ6, Q6ISQ2, Q6ISS1	Gene names	CER1
Domain Architecture	No domain graphic available
Description	Cerberus precursor (Cerberus-related protein).

SELPL_MOUSE
NC score	0.060618 (rank : 455)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	244	Target Neighborhood Hits	588	Shared Neighborhood Hits	10
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

PODXL_HUMAN
NC score	0.060410 (rank : 456)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	244	Target Neighborhood Hits	191	Shared Neighborhood Hits	7
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

VEGFC_MOUSE
NC score	0.060296 (rank : 457)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	244	Target Neighborhood Hits	119	Shared Neighborhood Hits	54
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

ADA17_HUMAN
NC score	0.060256 (rank : 458)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	244	Target Neighborhood Hits	223	Shared Neighborhood Hits	95
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

MASP1_HUMAN
NC score	0.059869 (rank : 459)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	244	Target Neighborhood Hits	369	Shared Neighborhood Hits	109
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

C1S_HUMAN
NC score	0.059618 (rank : 460)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	244	Target Neighborhood Hits	359	Shared Neighborhood Hits	109
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

MT1_MOUSE
NC score	0.059194 (rank : 461)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	244	Target Neighborhood Hits	72	Shared Neighborhood Hits	17
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

MASP1_MOUSE
NC score	0.058848 (rank : 462)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	244	Target Neighborhood Hits	364	Shared Neighborhood Hits	108
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

KR111_HUMAN
NC score	0.058552 (rank : 463)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	244	Target Neighborhood Hits	90	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IUC1	Gene names	KRTAP11-1, KAP11.1, KRTAP11.1
Domain Architecture
Description	Keratin-associated protein 11-1 (High sulfur keratin-associated protein 11.1).

MEP1A_HUMAN
NC score	0.058381 (rank : 464)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	244	Target Neighborhood Hits	162	Shared Neighborhood Hits	76
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

TNR16_HUMAN
NC score	0.058161 (rank : 465)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	244	Target Neighborhood Hits	183	Shared Neighborhood Hits	56
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

MEP1A_MOUSE
NC score	0.057863 (rank : 466)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	244	Target Neighborhood Hits	166	Shared Neighborhood Hits	77
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

ESM1_HUMAN
NC score	0.057672 (rank : 467)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	244	Target Neighborhood Hits	110	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

CSMD1_MOUSE
NC score	0.057609 (rank : 468)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	244	Target Neighborhood Hits	193	Shared Neighborhood Hits	47
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

TNR21_MOUSE
NC score	0.057144 (rank : 469)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	244	Target Neighborhood Hits	108	Shared Neighborhood Hits	29
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

CSMD1_HUMAN
NC score	0.057000 (rank : 470)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	244	Target Neighborhood Hits	176	Shared Neighborhood Hits	39
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

SON_MOUSE
NC score	0.056801 (rank : 471)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	244	Target Neighborhood Hits	957	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SPR2B_MOUSE
NC score	0.056659 (rank : 472)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	244	Target Neighborhood Hits	51	Shared Neighborhood Hits	16
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

CO6_HUMAN
NC score	0.056603 (rank : 473)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	244	Target Neighborhood Hits	331	Shared Neighborhood Hits	77
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

TINAL_HUMAN
NC score	0.056506 (rank : 474)	θ value	6.88961 (rank : 231)
Query Neighborhood Hits	244	Target Neighborhood Hits	50	Shared Neighborhood Hits	19
SwissProt Accessions	Q9GZM7, Q8TEJ9, Q8WZ23, Q96GZ4, Q96JW3	Gene names	TINAGL1, GIS5, LCN7, OLRG2, TINAGL
Domain Architecture	No domain graphic available
Description	Tubulointerstitial nephritis antigen-like precursor (Tubulointerstitial nephritis antigen-related protein) (TIN Ag-related protein) (TIN-Ag-RP) (Glucocorticoid-inducible protein 5) (Oxidized LDL-responsive gene 2 protein) (OLRG-2).

MUCEN_MOUSE
NC score	0.056458 (rank : 475)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	244	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R0H2, Q78KL2, Q9DCN9, Q9ULC1, Q9Z2I1	Gene names	Emcn, Muc14
Domain Architecture	No domain graphic available
Description	Endomucin precursor (Endomucin-1/2).

KR122_HUMAN
NC score	0.055823 (rank : 476)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	244	Target Neighborhood Hits	97	Shared Neighborhood Hits	43
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

MUC13_MOUSE
NC score	0.055735 (rank : 477)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	244	Target Neighborhood Hits	447	Shared Neighborhood Hits	97
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

SMOC1_HUMAN
NC score	0.055622 (rank : 478)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	244	Target Neighborhood Hits	81	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

HGFA_MOUSE
NC score	0.054216 (rank : 479)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	244	Target Neighborhood Hits	419	Shared Neighborhood Hits	112
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

CSMD3_HUMAN
NC score	0.054157 (rank : 480)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	244	Target Neighborhood Hits	199	Shared Neighborhood Hits	42
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

PGCB_HUMAN
NC score	0.054145 (rank : 481)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	244	Target Neighborhood Hits	478	Shared Neighborhood Hits	81
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

CSMD2_HUMAN
NC score	0.054042 (rank : 482)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	244	Target Neighborhood Hits	188	Shared Neighborhood Hits	40
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

EMR4_MOUSE
NC score	0.053928 (rank : 483)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	244	Target Neighborhood Hits	191	Shared Neighborhood Hits	79
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

KR124_HUMAN
NC score	0.053876 (rank : 484)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	244	Target Neighborhood Hits	124	Shared Neighborhood Hits	51
SwissProt Accessions	P60329	Gene names	KRTAP12-4, KAP12.4, KRTAP12.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-4 (Keratin-associated protein 12.4) (High sulfur keratin-associated protein 12.4).

IDD_HUMAN
NC score	0.053768 (rank : 485)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	244	Target Neighborhood Hits	127	Shared Neighborhood Hits	33
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

CFC1_MOUSE
NC score	0.052729 (rank : 486)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	244	Target Neighborhood Hits	125	Shared Neighborhood Hits	57
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

TIE1_HUMAN
NC score	0.052694 (rank : 487)	θ value	0.279714 (rank : 127)
Query Neighborhood Hits	244	Target Neighborhood Hits	1241	Shared Neighborhood Hits	136
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

RSPO3_MOUSE
NC score	0.052596 (rank : 488)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	244	Target Neighborhood Hits	120	Shared Neighborhood Hits	46
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

TDGF1_HUMAN
NC score	0.052201 (rank : 489)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	244	Target Neighborhood Hits	132	Shared Neighborhood Hits	60
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

TR11B_MOUSE
NC score	0.052107 (rank : 490)	θ value	0.279714 (rank : 129)
Query Neighborhood Hits	244	Target Neighborhood Hits	95	Shared Neighborhood Hits	23
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

LR37A_HUMAN
NC score	0.052096 (rank : 491)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	244	Target Neighborhood Hits	720	Shared Neighborhood Hits	12
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

ESM1_MOUSE
NC score	0.052009 (rank : 492)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	244	Target Neighborhood Hits	107	Shared Neighborhood Hits	44
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

CT127_HUMAN
NC score	0.052007 (rank : 493)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	244	Target Neighborhood Hits	67	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

CO8B_MOUSE
NC score	0.051940 (rank : 494)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	244	Target Neighborhood Hits	224	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

FA7_MOUSE
NC score	0.051850 (rank : 495)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	244	Target Neighborhood Hits	374	Shared Neighborhood Hits	119
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

TIE1_MOUSE
NC score	0.051477 (rank : 496)	θ value	0.21417 (rank : 119)
Query Neighborhood Hits	244	Target Neighborhood Hits	1266	Shared Neighborhood Hits	137
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

SMOC2_MOUSE
NC score	0.051438 (rank : 497)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	244	Target Neighborhood Hits	81	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).

CO7_HUMAN
NC score	0.051311 (rank : 498)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	244	Target Neighborhood Hits	278	Shared Neighborhood Hits	78
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO9_HUMAN
NC score	0.051268 (rank : 499)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	244	Target Neighborhood Hits	147	Shared Neighborhood Hits	52
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

SMOC2_HUMAN
NC score	0.051103 (rank : 500)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	244	Target Neighborhood Hits	88	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

MAVS_HUMAN
NC score	0.050814 (rank : 501)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	244	Target Neighborhood Hits	271	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

ENTK_MOUSE
NC score	0.050749 (rank : 502)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	244	Target Neighborhood Hits	338	Shared Neighborhood Hits	53
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

C163A_HUMAN
NC score	0.050673 (rank : 503)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	244	Target Neighborhood Hits	54	Shared Neighborhood Hits	11
SwissProt Accessions	Q86VB7, Q07898, Q07899, Q07900, Q07901, Q2VLH7	Gene names	CD163, M130
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M130 precursor (CD163 antigen) (Hemoglobin scavenger receptor) [Contains: Soluble CD163 (sCD163)].

RSPO4_MOUSE
NC score	0.050650 (rank : 504)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	244	Target Neighborhood Hits	110	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

TDGF2_HUMAN
NC score	0.050500 (rank : 505)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	244	Target Neighborhood Hits	131	Shared Neighborhood Hits	60
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

C163B_HUMAN
NC score	0.050289 (rank : 506)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	244	Target Neighborhood Hits	64	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NR16, Q6UWC2	Gene names	CD163L1, CD163B, M160
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M160 precursor (CD163 antigen-like 1) (CD163b antigen).

NDP_MOUSE
NC score	0.050282 (rank : 507)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	244	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	P48744	Gene names	Ndp, Ndph
Domain Architecture
Description	Norrin precursor (Norrie disease protein homolog).

RSPO1_HUMAN
NC score	0.050193 (rank : 508)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	244	Target Neighborhood Hits	101	Shared Neighborhood Hits	37
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

NET2_HUMAN
NC score	0.050147 (rank : 509)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	244	Target Neighborhood Hits	194	Shared Neighborhood Hits	76
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

COKA1_HUMAN
NC score	0.050073 (rank : 510)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	244	Target Neighborhood Hits	403	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

NET2_MOUSE
NC score	0.050016 (rank : 511)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	244	Target Neighborhood Hits	193	Shared Neighborhood Hits	78
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

TIE2_MOUSE
NC score	0.049384 (rank : 512)	θ value	0.279714 (rank : 128)
Query Neighborhood Hits	244	Target Neighborhood Hits	1204	Shared Neighborhood Hits	129
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

TIE2_HUMAN
NC score	0.044511 (rank : 513)	θ value	3.0926 (rank : 195)
Query Neighborhood Hits	244	Target Neighborhood Hits	1192	Shared Neighborhood Hits	129
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

ADAM8_HUMAN
NC score	0.041629 (rank : 514)	θ value	8.99809 (rank : 234)
Query Neighborhood Hits	244	Target Neighborhood Hits	327	Shared Neighborhood Hits	110
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

CNTP4_HUMAN
NC score	0.040845 (rank : 515)	θ value	3.0926 (rank : 189)
Query Neighborhood Hits	244	Target Neighborhood Hits	187	Shared Neighborhood Hits	59
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

ADA23_MOUSE
NC score	0.038891 (rank : 516)	θ value	1.38821 (rank : 162)
Query Neighborhood Hits	244	Target Neighborhood Hits	245	Shared Neighborhood Hits	102
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA23_HUMAN
NC score	0.037538 (rank : 517)	θ value	6.88961 (rank : 220)
Query Neighborhood Hits	244	Target Neighborhood Hits	235	Shared Neighborhood Hits	93
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ENPP2_MOUSE
NC score	0.033545 (rank : 518)	θ value	0.21417 (rank : 113)
Query Neighborhood Hits	244	Target Neighborhood Hits	66	Shared Neighborhood Hits	27
SwissProt Accessions	Q9R1E6, Q99LG9	Gene names	Enpp2, Npps2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENPP2_HUMAN
NC score	0.032264 (rank : 519)	θ value	0.365318 (rank : 132)
Query Neighborhood Hits	244	Target Neighborhood Hits	61	Shared Neighborhood Hits	27
SwissProt Accessions	Q13822, Q13827, Q15117	Gene names	ENPP2, ATX, PDNP2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) (Autotaxin) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ADM1B_MOUSE
NC score	0.031553 (rank : 520)	θ value	1.81305 (rank : 169)
Query Neighborhood Hits	244	Target Neighborhood Hits	236	Shared Neighborhood Hits	81
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

SRPX_MOUSE
NC score	0.031416 (rank : 521)	θ value	4.03905 (rank : 206)
Query Neighborhood Hits	244	Target Neighborhood Hits	75	Shared Neighborhood Hits	21
SwissProt Accessions	Q9R0M3, Q9R0M2	Gene names	Srpx
Domain Architecture	No domain graphic available
Description	Sushi-repeat-containing protein SRPX precursor (DRS protein).

FAM5C_MOUSE
NC score	0.031277 (rank : 522)	θ value	0.62314 (rank : 143)
Query Neighborhood Hits	244	Target Neighborhood Hits	22	Shared Neighborhood Hits	10
SwissProt Accessions	Q499E0, Q8K0R9	Gene names	Fam5c
Domain Architecture	No domain graphic available
Description	Protein FAM5C precursor.

FAM5C_HUMAN
NC score	0.031177 (rank : 523)	θ value	0.62314 (rank : 142)
Query Neighborhood Hits	244	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	Q76B58, O95726	Gene names	FAM5C, DBCCR1L, DBCCR1L1
Domain Architecture	No domain graphic available
Description	Protein FAM5C precursor (DBCCR1-like protein 1).

SRPX_HUMAN
NC score	0.030096 (rank : 524)	θ value	6.88961 (rank : 230)
Query Neighborhood Hits	244	Target Neighborhood Hits	69	Shared Neighborhood Hits	18
SwissProt Accessions	P78539, Q99652, Q99913	Gene names	SRPX, ETX1
Domain Architecture
Description	Sushi repeat-containing protein SRPX precursor.

TPA_MOUSE
NC score	0.028325 (rank : 525)	θ value	1.81305 (rank : 176)
Query Neighborhood Hits	244	Target Neighborhood Hits	335	Shared Neighborhood Hits	76
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

IGF1R_MOUSE
NC score	0.023178 (rank : 526)	θ value	0.0330416 (rank : 78)
Query Neighborhood Hits	244	Target Neighborhood Hits	973	Shared Neighborhood Hits	84
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IGF1R_HUMAN
NC score	0.021457 (rank : 527)	θ value	1.81305 (rank : 171)
Query Neighborhood Hits	244	Target Neighborhood Hits	977	Shared Neighborhood Hits	81
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

INSR_HUMAN
NC score	0.017208 (rank : 528)	θ value	5.27518 (rank : 212)
Query Neighborhood Hits	244	Target Neighborhood Hits	963	Shared Neighborhood Hits	76
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

INSR_MOUSE
NC score	0.017123 (rank : 529)	θ value	4.03905 (rank : 201)
Query Neighborhood Hits	244	Target Neighborhood Hits	968	Shared Neighborhood Hits	68
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

ALDOB_HUMAN
NC score	0.013056 (rank : 530)	θ value	3.0926 (rank : 185)
Query Neighborhood Hits	244	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	P05062, Q13741, Q13742	Gene names	ALDOB, ALDB
Domain Architecture
Description	Fructose-bisphosphate aldolase B (EC 4.1.2.13) (Liver-type aldolase).

ALDOB_MOUSE
NC score	0.013022 (rank : 531)	θ value	3.0926 (rank : 186)
Query Neighborhood Hits	244	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q91Y97, Q8K034, Q91W73	Gene names	Aldob, Aldo2
Domain Architecture
Description	Fructose-bisphosphate aldolase B (EC 4.1.2.13) (Liver-type aldolase) (Aldolase 2).

MTP18_HUMAN
NC score	0.009867 (rank : 532)	θ value	8.99809 (rank : 241)
Query Neighborhood Hits	244	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UDX5, Q9H3K1, Q9P0N6	Gene names	MTP18
Domain Architecture	No domain graphic available
Description	Mitochondrial 18 kDa protein (MTP18).

ERR3_HUMAN
NC score	0.001879 (rank : 533)	θ value	8.99809 (rank : 236)
Query Neighborhood Hits	244	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	P62508, O75454, O96021, Q68DA0, Q6P274, Q6PK28, Q6TS38, Q9R1F3, Q9UNJ4	Gene names	ESRRG, ERR3, ERRG2, KIAA0832, NR3B3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (ERR gamma-2).

ERR3_MOUSE
NC score	0.001879 (rank : 534)	θ value	8.99809 (rank : 237)
Query Neighborhood Hits	244	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	P62509, O75454, O96021, Q8CHC9, Q9R1F3	Gene names	Esrrg, Err3, Kiaa0832, Nr3b3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3).