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Network neighborhood for query Sequence : IDD_HUMAN

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IDD_HUMAN
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IDD_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	127	Target Neighborhood Hits	127	Shared Neighborhood Hits	127
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

IDD_MOUSE
θ value	0 (rank : 2)	NC score	0.983115 (rank : 2)
Query Neighborhood Hits	127	Target Neighborhood Hits	151	Shared Neighborhood Hits	106
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

LRP5_HUMAN
θ value	1.47974e-10 (rank : 3)	NC score	0.505857 (rank : 4)
Query Neighborhood Hits	127	Target Neighborhood Hits	224	Shared Neighborhood Hits	63
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LRP5_MOUSE
θ value	1.47974e-10 (rank : 4)	NC score	0.505701 (rank : 5)
Query Neighborhood Hits	127	Target Neighborhood Hits	236	Shared Neighborhood Hits	64
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

LRP6_HUMAN
θ value	9.59137e-10 (rank : 5)	NC score	0.495637 (rank : 7)
Query Neighborhood Hits	127	Target Neighborhood Hits	235	Shared Neighborhood Hits	65
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
θ value	9.59137e-10 (rank : 6)	NC score	0.496435 (rank : 6)
Query Neighborhood Hits	127	Target Neighborhood Hits	232	Shared Neighborhood Hits	65
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LDLR_MOUSE
θ value	8.11959e-09 (rank : 7)	NC score	0.429681 (rank : 10)
Query Neighborhood Hits	127	Target Neighborhood Hits	382	Shared Neighborhood Hits	71
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LY75_HUMAN
θ value	1.17247e-07 (rank : 8)	NC score	0.263995 (rank : 30)
Query Neighborhood Hits	127	Target Neighborhood Hits	169	Shared Neighborhood Hits	41
SwissProt Accessions	O60449, O75913, Q7Z575, Q7Z577	Gene names	LY75, CD205
Domain Architecture
Description	Lymphocyte antigen 75 precursor (DEC-205) (gp200-MR6) (CD205 antigen).

LY75_MOUSE
θ value	1.99992e-07 (rank : 9)	NC score	0.270031 (rank : 29)
Query Neighborhood Hits	127	Target Neighborhood Hits	155	Shared Neighborhood Hits	43
SwissProt Accessions	Q60767, Q8C7T3, Q91XL8, Q9QUZ6	Gene names	Ly75, Cd205
Domain Architecture
Description	Lymphocyte antigen 75 precursor (DEC-205) (CD205 antigen).

LRP8_HUMAN
θ value	2.88788e-06 (rank : 10)	NC score	0.427626 (rank : 12)
Query Neighborhood Hits	127	Target Neighborhood Hits	346	Shared Neighborhood Hits	69
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LDLR_HUMAN
θ value	4.92598e-06 (rank : 11)	NC score	0.414737 (rank : 17)
Query Neighborhood Hits	127	Target Neighborhood Hits	375	Shared Neighborhood Hits	69
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

ST14_HUMAN
θ value	6.43352e-06 (rank : 12)	NC score	0.247152 (rank : 32)
Query Neighborhood Hits	127	Target Neighborhood Hits	409	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

CORIN_HUMAN
θ value	2.44474e-05 (rank : 13)	NC score	0.245415 (rank : 34)
Query Neighborhood Hits	127	Target Neighborhood Hits	453	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

VLDLR_HUMAN
θ value	2.44474e-05 (rank : 14)	NC score	0.415233 (rank : 16)
Query Neighborhood Hits	127	Target Neighborhood Hits	383	Shared Neighborhood Hits	70
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

LRP1_HUMAN
θ value	3.19293e-05 (rank : 15)	NC score	0.384636 (rank : 23)
Query Neighborhood Hits	127	Target Neighborhood Hits	617	Shared Neighborhood Hits	77
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP4_HUMAN
θ value	3.19293e-05 (rank : 16)	NC score	0.428356 (rank : 11)
Query Neighborhood Hits	127	Target Neighborhood Hits	355	Shared Neighborhood Hits	70
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP4_MOUSE
θ value	3.19293e-05 (rank : 17)	NC score	0.424691 (rank : 13)
Query Neighborhood Hits	127	Target Neighborhood Hits	351	Shared Neighborhood Hits	69
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LRP8_MOUSE
θ value	3.19293e-05 (rank : 18)	NC score	0.416932 (rank : 15)
Query Neighborhood Hits	127	Target Neighborhood Hits	385	Shared Neighborhood Hits	69
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP2_HUMAN
θ value	4.1701e-05 (rank : 19)	NC score	0.409468 (rank : 19)
Query Neighborhood Hits	127	Target Neighborhood Hits	573	Shared Neighborhood Hits	78
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

PGBM_HUMAN
θ value	7.1131e-05 (rank : 20)	NC score	0.204066 (rank : 49)
Query Neighborhood Hits	127	Target Neighborhood Hits	1113	Shared Neighborhood Hits	75
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGBM_MOUSE
θ value	9.29e-05 (rank : 21)	NC score	0.213499 (rank : 44)
Query Neighborhood Hits	127	Target Neighborhood Hits	1073	Shared Neighborhood Hits	77
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

VLDLR_MOUSE
θ value	9.29e-05 (rank : 22)	NC score	0.414022 (rank : 18)
Query Neighborhood Hits	127	Target Neighborhood Hits	360	Shared Neighborhood Hits	70
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

CORIN_MOUSE
θ value	0.000158464 (rank : 23)	NC score	0.244198 (rank : 35)
Query Neighborhood Hits	127	Target Neighborhood Hits	451	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

LRP1B_HUMAN
θ value	0.00035302 (rank : 24)	NC score	0.384227 (rank : 24)
Query Neighborhood Hits	127	Target Neighborhood Hits	602	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1B_MOUSE
θ value	0.00035302 (rank : 25)	NC score	0.384734 (rank : 22)
Query Neighborhood Hits	127	Target Neighborhood Hits	606	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

CD320_HUMAN
θ value	0.000461057 (rank : 26)	NC score	0.544291 (rank : 3)
Query Neighborhood Hits	127	Target Neighborhood Hits	103	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

LRP3_HUMAN
θ value	0.000461057 (rank : 27)	NC score	0.421983 (rank : 14)
Query Neighborhood Hits	127	Target Neighborhood Hits	280	Shared Neighborhood Hits	64
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

SORL_HUMAN
θ value	0.000461057 (rank : 28)	NC score	0.384754 (rank : 20)
Query Neighborhood Hits	127	Target Neighborhood Hits	440	Shared Neighborhood Hits	69
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SORL_MOUSE
θ value	0.000461057 (rank : 29)	NC score	0.384749 (rank : 21)
Query Neighborhood Hits	127	Target Neighborhood Hits	439	Shared Neighborhood Hits	69
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

CSPG3_HUMAN
θ value	0.000786445 (rank : 30)	NC score	0.160337 (rank : 69)
Query Neighborhood Hits	127	Target Neighborhood Hits	676	Shared Neighborhood Hits	57
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

ST14_MOUSE
θ value	0.00102713 (rank : 31)	NC score	0.239623 (rank : 37)
Query Neighborhood Hits	127	Target Neighborhood Hits	419	Shared Neighborhood Hits	66
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

ENTK_HUMAN
θ value	0.00175202 (rank : 32)	NC score	0.157867 (rank : 71)
Query Neighborhood Hits	127	Target Neighborhood Hits	310	Shared Neighborhood Hits	60
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

LRP12_HUMAN
θ value	0.00175202 (rank : 33)	NC score	0.380416 (rank : 25)
Query Neighborhood Hits	127	Target Neighborhood Hits	205	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
θ value	0.00175202 (rank : 34)	NC score	0.380296 (rank : 26)
Query Neighborhood Hits	127	Target Neighborhood Hits	180	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

MRC1_HUMAN
θ value	0.00175202 (rank : 35)	NC score	0.218999 (rank : 43)
Query Neighborhood Hits	127	Target Neighborhood Hits	157	Shared Neighborhood Hits	44
SwissProt Accessions	P22897	Gene names	MRC1
Domain Architecture
Description	Macrophage mannose receptor 1 precursor (MMR) (CD206 antigen).

ENTK_MOUSE
θ value	0.00228821 (rank : 36)	NC score	0.160462 (rank : 68)
Query Neighborhood Hits	127	Target Neighborhood Hits	338	Shared Neighborhood Hits	62
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

SSPO_MOUSE
θ value	0.00298849 (rank : 37)	NC score	0.284937 (rank : 27)
Query Neighborhood Hits	127	Target Neighborhood Hits	800	Shared Neighborhood Hits	81
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

CSPG3_MOUSE
θ value	0.00509761 (rank : 38)	NC score	0.152737 (rank : 81)
Query Neighborhood Hits	127	Target Neighborhood Hits	657	Shared Neighborhood Hits	56
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

LRP10_HUMAN
θ value	0.00509761 (rank : 39)	NC score	0.443328 (rank : 8)
Query Neighborhood Hits	127	Target Neighborhood Hits	197	Shared Neighborhood Hits	63
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP10_MOUSE
θ value	0.00665767 (rank : 40)	NC score	0.440315 (rank : 9)
Query Neighborhood Hits	127	Target Neighborhood Hits	169	Shared Neighborhood Hits	60
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

RXFP2_HUMAN
θ value	0.00869519 (rank : 41)	NC score	0.122524 (rank : 120)
Query Neighborhood Hits	127	Target Neighborhood Hits	736	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WXD0	Gene names	RXFP2, GPR106, GREAT, LGR8
Domain Architecture
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-rich repeat-containing G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106).

TMPS7_MOUSE
θ value	0.0113563 (rank : 42)	NC score	0.205404 (rank : 48)
Query Neighborhood Hits	127	Target Neighborhood Hits	275	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

CLC4M_HUMAN
θ value	0.0193708 (rank : 43)	NC score	0.157340 (rank : 72)
Query Neighborhood Hits	127	Target Neighborhood Hits	291	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H2X3, Q69F40, Q969M4, Q96QP3, Q96QP4, Q96QP5, Q96QP6, Q9BXS3, Q9H2Q9, Q9H8F0, Q9Y2A8	Gene names	CLEC4M, CD209L, CD209L1
Domain Architecture
Description	C-type lectin domain family 4 member M (CD209 antigen-like protein 1) (Dendritic cell-specific ICAM-3-grabbing nonintegrin 2) (DC-SIGN2) (DC-SIGN-related protein) (DC-SIGNR) (Liver/lymph node-specific ICAM- 3-grabbing nonintegrin) (L-SIGN) (CD299 antigen).

MFRP_HUMAN
θ value	0.0252991 (rank : 44)	NC score	0.220249 (rank : 40)
Query Neighborhood Hits	127	Target Neighborhood Hits	165	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MRC1_MOUSE
θ value	0.0252991 (rank : 45)	NC score	0.207987 (rank : 46)
Query Neighborhood Hits	127	Target Neighborhood Hits	156	Shared Neighborhood Hits	43
SwissProt Accessions	Q61830, Q8C502	Gene names	Mrc1
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 1 precursor (MMR) (CD206 antigen).

MRC2_MOUSE
θ value	0.0252991 (rank : 46)	NC score	0.211827 (rank : 45)
Query Neighborhood Hits	127	Target Neighborhood Hits	159	Shared Neighborhood Hits	43
SwissProt Accessions	Q64449, Q6ZQ64, Q8C6P0	Gene names	Mrc2, Kiaa0709
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 2 precursor (Lectin lambda) (CD280 antigen).

TMPS7_HUMAN
θ value	0.0252991 (rank : 47)	NC score	0.203666 (rank : 50)
Query Neighborhood Hits	127	Target Neighborhood Hits	275	Shared Neighborhood Hits	58
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

ATRN_HUMAN
θ value	0.0330416 (rank : 48)	NC score	0.145953 (rank : 90)
Query Neighborhood Hits	127	Target Neighborhood Hits	525	Shared Neighborhood Hits	62
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATRN_MOUSE
θ value	0.0330416 (rank : 49)	NC score	0.143623 (rank : 94)
Query Neighborhood Hits	127	Target Neighborhood Hits	519	Shared Neighborhood Hits	57
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

CD72_HUMAN
θ value	0.0330416 (rank : 50)	NC score	0.151020 (rank : 82)
Query Neighborhood Hits	127	Target Neighborhood Hits	345	Shared Neighborhood Hits	35
SwissProt Accessions	P21854	Gene names	CD72
Domain Architecture
Description	B-cell differentiation antigen CD72 (Lyb-2).

TMPS3_HUMAN
θ value	0.0330416 (rank : 51)	NC score	0.107813 (rank : 147)
Query Neighborhood Hits	127	Target Neighborhood Hits	245	Shared Neighborhood Hits	58
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

CRDL2_HUMAN
θ value	0.0431538 (rank : 52)	NC score	0.114219 (rank : 134)
Query Neighborhood Hits	127	Target Neighborhood Hits	99	Shared Neighborhood Hits	14
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

SPIT1_HUMAN
θ value	0.0431538 (rank : 53)	NC score	0.279287 (rank : 28)
Query Neighborhood Hits	127	Target Neighborhood Hits	100	Shared Neighborhood Hits	54
SwissProt Accessions	O43278, Q7Z7D2	Gene names	SPINT1, HAI1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

CLC10_HUMAN
θ value	0.0736092 (rank : 54)	NC score	0.164002 (rank : 64)
Query Neighborhood Hits	127	Target Neighborhood Hits	134	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IUN9, Q14538, Q6PIW3	Gene names	CLEC10A, CLECSF14, HML
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 10 member A (C-type lectin superfamily member 14) (Macrophage lectin 2) (CD301 antigen).

CRDL2_MOUSE
θ value	0.0736092 (rank : 55)	NC score	0.111820 (rank : 139)
Query Neighborhood Hits	127	Target Neighborhood Hits	81	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

RXFP2_MOUSE
θ value	0.0736092 (rank : 56)	NC score	0.105453 (rank : 153)
Query Neighborhood Hits	127	Target Neighborhood Hits	760	Shared Neighborhood Hits	57
SwissProt Accessions	Q91ZZ5	Gene names	Rxfp2, Gpr106, Great, Lgr8
Domain Architecture
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-rich repeat-containing G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106).

CSPG2_HUMAN
θ value	0.0961366 (rank : 57)	NC score	0.141687 (rank : 96)
Query Neighborhood Hits	127	Target Neighborhood Hits	681	Shared Neighborhood Hits	60
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CSPG2_MOUSE
θ value	0.0961366 (rank : 58)	NC score	0.141958 (rank : 95)
Query Neighborhood Hits	127	Target Neighborhood Hits	711	Shared Neighborhood Hits	60
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

MRC2_HUMAN
θ value	0.0961366 (rank : 59)	NC score	0.205459 (rank : 47)
Query Neighborhood Hits	127	Target Neighborhood Hits	162	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UBG0, Q7LGE7, Q9Y5P9	Gene names	MRC2, ENDO180, KIAA0709, UPARAP
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 2 precursor (Urokinase receptor-associated protein) (Endocytic receptor 180) (CD280 antigen).

TMPS3_MOUSE
θ value	0.0961366 (rank : 60)	NC score	0.102256 (rank : 165)
Query Neighborhood Hits	127	Target Neighborhood Hits	239	Shared Neighborhood Hits	52
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

CHRD_HUMAN
θ value	0.125558 (rank : 61)	NC score	0.104575 (rank : 158)
Query Neighborhood Hits	127	Target Neighborhood Hits	102	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

REG1B_HUMAN
θ value	0.125558 (rank : 62)	NC score	0.155234 (rank : 77)
Query Neighborhood Hits	127	Target Neighborhood Hits	120	Shared Neighborhood Hits	39
SwissProt Accessions	P48304	Gene names	REG1B, REGL
Domain Architecture
Description	Lithostathine 1 beta precursor (Regenerating protein I beta).

CLC1A_MOUSE
θ value	0.21417 (rank : 63)	NC score	0.148041 (rank : 85)
Query Neighborhood Hits	127	Target Neighborhood Hits	100	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BWY2, Q7TPX7, Q8BMH5	Gene names	Clec1a
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 1 member A.

CO8B_MOUSE
θ value	0.21417 (rank : 64)	NC score	0.186580 (rank : 55)
Query Neighborhood Hits	127	Target Neighborhood Hits	224	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

FREM1_HUMAN
θ value	0.21417 (rank : 65)	NC score	0.099564 (rank : 172)
Query Neighborhood Hits	127	Target Neighborhood Hits	170	Shared Neighborhood Hits	41
SwissProt Accessions	Q5H8C1, Q5VV00, Q5VV01, Q6MZI4, Q8NEG9, Q96LI3	Gene names	FREM1, C9orf154
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

IRX4_MOUSE
θ value	0.21417 (rank : 66)	NC score	0.026448 (rank : 473)
Query Neighborhood Hits	127	Target Neighborhood Hits	286	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QY61	Gene names	Irx4, Irxa3
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-4 (Iroquois homeobox protein 4) (Homeodomain protein IRXA3).

RXFP1_HUMAN
θ value	0.21417 (rank : 67)	NC score	0.082811 (rank : 235)
Query Neighborhood Hits	127	Target Neighborhood Hits	816	Shared Neighborhood Hits	53
SwissProt Accessions	Q9HBX9	Gene names	RXFP1, LGR7
Domain Architecture
Description	Relaxin receptor 1 (Relaxin family peptide receptor 1) (Leucine-rich repeat-containing G-protein coupled receptor 7).

C209A_MOUSE
θ value	0.279714 (rank : 68)	NC score	0.161389 (rank : 67)
Query Neighborhood Hits	127	Target Neighborhood Hits	117	Shared Neighborhood Hits	39
SwissProt Accessions	Q91ZX1, Q3TAT9, Q91ZW5	Gene names	Cd209a, Cire
Domain Architecture
Description	CD209 antigen-like protein A (Dendritic cell-specific ICAM-3-grabbing nonintegrin) (DC-SIGN).

ASGR2_HUMAN
θ value	0.365318 (rank : 69)	NC score	0.153108 (rank : 80)
Query Neighborhood Hits	127	Target Neighborhood Hits	121	Shared Neighborhood Hits	38
SwissProt Accessions	P07307, O00448, Q03969	Gene names	ASGR2
Domain Architecture
Description	Asialoglycoprotein receptor 2 (ASGP-R 2) (ASGPR 2) (Hepatic lectin H2).

C209C_MOUSE
θ value	0.365318 (rank : 70)	NC score	0.149451 (rank : 84)
Query Neighborhood Hits	127	Target Neighborhood Hits	114	Shared Neighborhood Hits	37
SwissProt Accessions	Q91ZW9	Gene names	Cd209c
Domain Architecture
Description	CD209 antigen-like protein C (DC-SIGN-related protein 2) (DC-SIGNR2).

CD248_HUMAN
θ value	0.365318 (rank : 71)	NC score	0.155837 (rank : 74)
Query Neighborhood Hits	127	Target Neighborhood Hits	679	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CO8B_HUMAN
θ value	0.365318 (rank : 72)	NC score	0.185776 (rank : 56)
Query Neighborhood Hits	127	Target Neighborhood Hits	199	Shared Neighborhood Hits	57
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CHRD_MOUSE
θ value	0.47712 (rank : 73)	NC score	0.089127 (rank : 208)
Query Neighborhood Hits	127	Target Neighborhood Hits	102	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

CLC4E_MOUSE
θ value	0.47712 (rank : 74)	NC score	0.155398 (rank : 76)
Query Neighborhood Hits	127	Target Neighborhood Hits	113	Shared Neighborhood Hits	39
SwissProt Accessions	Q9R0Q8	Gene names	Clec4e, Clecsf9, Mincle
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member E (C-type lectin superfamily member 9) (Macrophage-inducible C-type lectin).

CRIM1_HUMAN
θ value	0.47712 (rank : 75)	NC score	0.092359 (rank : 196)
Query Neighborhood Hits	127	Target Neighborhood Hits	362	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

CLC6A_HUMAN
θ value	0.62314 (rank : 76)	NC score	0.157266 (rank : 73)
Query Neighborhood Hits	127	Target Neighborhood Hits	119	Shared Neighborhood Hits	41
SwissProt Accessions	Q6EIG7	Gene names	CLEC6A, CLECSF10, DECTIN2
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 6 member A (C-type lectin superfamily member 10) (Dendritic cell-associated lectin 2) (DC-associated C-type lectin-2) (DECTIN-2).

CLC6A_MOUSE
θ value	0.62314 (rank : 77)	NC score	0.155063 (rank : 78)
Query Neighborhood Hits	127	Target Neighborhood Hits	111	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JKF4, Q9JKF2, Q9JKF3	Gene names	Clec6a, Clecsf10, Dectin2
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 6 member A (C-type lectin superfamily member 10) (Dendritic cell-associated lectin 2) (DC-associated C-type lectin-2) (DECTIN-2).

OLR1_MOUSE
θ value	0.62314 (rank : 78)	NC score	0.101320 (rank : 167)
Query Neighborhood Hits	127	Target Neighborhood Hits	596	Shared Neighborhood Hits	38
SwissProt Accessions	Q9EQ09	Gene names	Olr1, Lox1
Domain Architecture	No domain graphic available
Description	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, soluble form].

C209D_MOUSE
θ value	0.813845 (rank : 79)	NC score	0.150769 (rank : 83)
Query Neighborhood Hits	127	Target Neighborhood Hits	120	Shared Neighborhood Hits	40
SwissProt Accessions	Q91ZW8, Q8VIK4	Gene names	Cd209d
Domain Architecture
Description	CD209 antigen-like protein D (DC-SIGN-related protein 3) (DC-SIGNR3).

CFAI_HUMAN
θ value	0.813845 (rank : 80)	NC score	0.174363 (rank : 61)
Query Neighborhood Hits	127	Target Neighborhood Hits	289	Shared Neighborhood Hits	57
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

VTDB_MOUSE
θ value	0.813845 (rank : 81)	NC score	0.052587 (rank : 443)
Query Neighborhood Hits	127	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	P21614, Q7TS97, Q91XG1, Q9CY31	Gene names	Gc
Domain Architecture
Description	Vitamin D-binding protein precursor (DBP) (Group-specific component) (Gc-globulin) (VDB).

ASGR2_MOUSE
θ value	1.38821 (rank : 82)	NC score	0.147357 (rank : 87)
Query Neighborhood Hits	127	Target Neighborhood Hits	123	Shared Neighborhood Hits	40
SwissProt Accessions	P24721	Gene names	Asgr2, Asgr-2
Domain Architecture
Description	Asialoglycoprotein receptor 2 (ASGP-R 2) (ASGPR 2) (Hepatic lectin 2) (MHL-2).

BMPER_MOUSE
θ value	1.38821 (rank : 83)	NC score	0.070962 (rank : 297)
Query Neighborhood Hits	127	Target Neighborhood Hits	194	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

CLC4A_HUMAN
θ value	1.38821 (rank : 84)	NC score	0.154672 (rank : 79)
Query Neighborhood Hits	127	Target Neighborhood Hits	114	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UMR7, Q8WXW9, Q9H2Z9, Q9NS33, Q9UI34	Gene names	CLEC4A, CLECSF6, DCIR, LLIR
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member A (C-type lectin superfamily member 6) (Dendritic cell immunoreceptor) (Lectin-like immunoreceptor) (C-type lectin DDB27).

RUNX3_MOUSE
θ value	1.38821 (rank : 85)	NC score	0.024462 (rank : 474)
Query Neighborhood Hits	127	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	Q64131, Q99P92, Q9R199	Gene names	Runx3, Aml2, Cbfa3, Pebp2a3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

TMPS9_MOUSE
θ value	1.38821 (rank : 86)	NC score	0.112995 (rank : 137)
Query Neighborhood Hits	127	Target Neighborhood Hits	296	Shared Neighborhood Hits	52
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

VTDB_HUMAN
θ value	1.38821 (rank : 87)	NC score	0.040346 (rank : 472)
Query Neighborhood Hits	127	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P02774, Q16309, Q16310	Gene names	GC
Domain Architecture
Description	Vitamin D-binding protein precursor (DBP) (Group-specific component) (Gc-globulin) (VDB).

C209B_MOUSE
θ value	1.81305 (rank : 88)	NC score	0.146935 (rank : 88)
Query Neighborhood Hits	127	Target Neighborhood Hits	140	Shared Neighborhood Hits	39
SwissProt Accessions	Q8CJ91, Q8BGZ0, Q8BHK7, Q8CJ86, Q8CJ87, Q8CJ88, Q8CJ89, Q8CJ90, Q8CJ92, Q8CJ93, Q8CJ94, Q91ZW4, Q91ZX0, Q9D8V4	Gene names	Cd209b
Domain Architecture
Description	CD209 antigen-like protein B (DC-SIGN-related protein 1) (DC-SIGNR1) (OtB7).

CD248_MOUSE
θ value	1.81305 (rank : 89)	NC score	0.147470 (rank : 86)
Query Neighborhood Hits	127	Target Neighborhood Hits	578	Shared Neighborhood Hits	42
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

EGR4_HUMAN
θ value	1.81305 (rank : 90)	NC score	-0.001193 (rank : 485)
Query Neighborhood Hits	127	Target Neighborhood Hits	939	Shared Neighborhood Hits	4
SwissProt Accessions	Q05215	Gene names	EGR4
Domain Architecture
Description	Early growth response protein 4 (EGR-4) (AT133).

KLRBB_MOUSE
θ value	1.81305 (rank : 91)	NC score	0.133084 (rank : 102)
Query Neighborhood Hits	127	Target Neighborhood Hits	105	Shared Neighborhood Hits	39
SwissProt Accessions	P27812	Gene names	Klrb1b, Ly55-b, Ly55b
Domain Architecture
Description	Natural killer cell surface protein P1-34 (NKR-P1 34).

MFRP_MOUSE
θ value	1.81305 (rank : 92)	NC score	0.186784 (rank : 54)
Query Neighborhood Hits	127	Target Neighborhood Hits	166	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

REG4_HUMAN
θ value	1.81305 (rank : 93)	NC score	0.146405 (rank : 89)
Query Neighborhood Hits	127	Target Neighborhood Hits	105	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BYZ8, Q8NER6, Q8NER7	Gene names	REG4, GISP, RELP
Domain Architecture	No domain graphic available
Description	Regenerating islet-derived protein 4 precursor (Reg IV) (REG-like protein) (Gastrointestinal secretory protein).

ASGR1_MOUSE
θ value	2.36792 (rank : 94)	NC score	0.144185 (rank : 93)
Query Neighborhood Hits	127	Target Neighborhood Hits	135	Shared Neighborhood Hits	39
SwissProt Accessions	P34927, Q64363	Gene names	Asgr1, Asgr-1
Domain Architecture
Description	Asialoglycoprotein receptor 1 (ASGPR 1) (ASGP-R 1) (Hepatic lectin 1) (MHL-1).

CO6_HUMAN
θ value	2.36792 (rank : 95)	NC score	0.187980 (rank : 53)
Query Neighborhood Hits	127	Target Neighborhood Hits	331	Shared Neighborhood Hits	66
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

MAGE1_HUMAN
θ value	2.36792 (rank : 96)	NC score	0.007963 (rank : 481)
Query Neighborhood Hits	127	Target Neighborhood Hits	1389	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

TMPS6_HUMAN
θ value	2.36792 (rank : 97)	NC score	0.178853 (rank : 60)
Query Neighborhood Hits	127	Target Neighborhood Hits	338	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS9_HUMAN
θ value	2.36792 (rank : 98)	NC score	0.118996 (rank : 125)
Query Neighborhood Hits	127	Target Neighborhood Hits	276	Shared Neighborhood Hits	57
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

CFAI_MOUSE
θ value	3.0926 (rank : 99)	NC score	0.162253 (rank : 66)
Query Neighborhood Hits	127	Target Neighborhood Hits	290	Shared Neighborhood Hits	57
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CLC4D_HUMAN
θ value	3.0926 (rank : 100)	NC score	0.145393 (rank : 91)
Query Neighborhood Hits	127	Target Neighborhood Hits	111	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WXI8, Q8N5J5	Gene names	CLEC4D, CLECSF8, MCL
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member D (C-type lectin superfamily member 8) (C-type lectin-like receptor 6) (CLEC-6).

LRP11_MOUSE
θ value	3.0926 (rank : 101)	NC score	0.249929 (rank : 31)
Query Neighborhood Hits	127	Target Neighborhood Hits	81	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CB67, Q8C7Y7	Gene names	Lrp11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

MUC5B_HUMAN
θ value	3.0926 (rank : 102)	NC score	0.067960 (rank : 316)
Query Neighborhood Hits	127	Target Neighborhood Hits	1020	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

OSBL3_HUMAN
θ value	3.0926 (rank : 103)	NC score	0.010940 (rank : 477)
Query Neighborhood Hits	127	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

CO8A_MOUSE
θ value	4.03905 (rank : 104)	NC score	0.183188 (rank : 59)
Query Neighborhood Hits	127	Target Neighborhood Hits	182	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

KRA47_HUMAN
θ value	4.03905 (rank : 105)	NC score	0.061662 (rank : 358)
Query Neighborhood Hits	127	Target Neighborhood Hits	204	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

MGR6_MOUSE
θ value	4.03905 (rank : 106)	NC score	0.010038 (rank : 479)
Query Neighborhood Hits	127	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	Q5NCH9	Gene names	Grm6, Gprc1f, Mglur6
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

REG3A_HUMAN
θ value	4.03905 (rank : 107)	NC score	0.128100 (rank : 111)
Query Neighborhood Hits	127	Target Neighborhood Hits	87	Shared Neighborhood Hits	40
SwissProt Accessions	Q06141	Gene names	REG3A, HIP, PAP, PAP1
Domain Architecture
Description	Regenerating islet-derived protein 3 alpha precursor (Reg III-alpha) (Pancreatitis-associated protein 1).

TRBM_MOUSE
θ value	4.03905 (rank : 108)	NC score	0.133054 (rank : 103)
Query Neighborhood Hits	127	Target Neighborhood Hits	361	Shared Neighborhood Hits	51
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

CLC4C_HUMAN
θ value	5.27518 (rank : 109)	NC score	0.138259 (rank : 98)
Query Neighborhood Hits	127	Target Neighborhood Hits	111	Shared Neighborhood Hits	38
SwissProt Accessions	Q8WTT0, Q3T1C3, Q6UXS8, Q8WXX8	Gene names	CLEC4C, BDCA2, CLECSF11, CLECSF7, DLEC, HECL
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member C (C-type lectin superfamily member 7) (Blood dendritic cell antigen 2 protein) (BDCA-2) (Dendritic lectin) (CD303 antigen).

CO1A1_MOUSE
θ value	5.27518 (rank : 110)	NC score	0.019243 (rank : 475)
Query Neighborhood Hits	127	Target Neighborhood Hits	457	Shared Neighborhood Hits	16
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

FBN1_MOUSE
θ value	5.27518 (rank : 111)	NC score	0.102347 (rank : 164)
Query Neighborhood Hits	127	Target Neighborhood Hits	563	Shared Neighborhood Hits	55
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

MGR6_HUMAN
θ value	5.27518 (rank : 112)	NC score	0.009454 (rank : 480)
Query Neighborhood Hits	127	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	O15303	Gene names	GRM6, GPRC1F, MGLUR6
Domain Architecture
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

TRBM_HUMAN
θ value	5.27518 (rank : 113)	NC score	0.123441 (rank : 116)
Query Neighborhood Hits	127	Target Neighborhood Hits	339	Shared Neighborhood Hits	45
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRI34_MOUSE
θ value	5.27518 (rank : 114)	NC score	0.006336 (rank : 483)
Query Neighborhood Hits	127	Target Neighborhood Hits	332	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

ASGR1_HUMAN
θ value	6.88961 (rank : 115)	NC score	0.136951 (rank : 99)
Query Neighborhood Hits	127	Target Neighborhood Hits	137	Shared Neighborhood Hits	39
SwissProt Accessions	P07306	Gene names	ASGR1
Domain Architecture
Description	Asialoglycoprotein receptor 1 (ASGPR 1) (ASGP-R 1) (Hepatic lectin H1).

KRA44_HUMAN
θ value	6.88961 (rank : 116)	NC score	0.055795 (rank : 414)
Query Neighborhood Hits	127	Target Neighborhood Hits	162	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

MAP4_MOUSE
θ value	6.88961 (rank : 117)	NC score	0.010739 (rank : 478)
Query Neighborhood Hits	127	Target Neighborhood Hits	409	Shared Neighborhood Hits	7
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

SPIT1_MOUSE
θ value	6.88961 (rank : 118)	NC score	0.219776 (rank : 41)
Query Neighborhood Hits	127	Target Neighborhood Hits	96	Shared Neighborhood Hits	57
SwissProt Accessions	Q9R097	Gene names	Spint1, Hai1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

BIN1_MOUSE
θ value	8.99809 (rank : 119)	NC score	0.007408 (rank : 482)
Query Neighborhood Hits	127	Target Neighborhood Hits	283	Shared Neighborhood Hits	4
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

CAC1F_HUMAN
θ value	8.99809 (rank : 120)	NC score	0.002934 (rank : 484)
Query Neighborhood Hits	127	Target Neighborhood Hits	141	Shared Neighborhood Hits	3
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CLC5A_HUMAN
θ value	8.99809 (rank : 121)	NC score	0.107339 (rank : 148)
Query Neighborhood Hits	127	Target Neighborhood Hits	89	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NY25, Q9UKQ0	Gene names	CLEC5A, CLECSF5, MDL1
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 5 member A (C-type lectin superfamily member 5) (Myeloid DAP12-associating lectin) (MDL-1).

FRAS1_HUMAN
θ value	8.99809 (rank : 122)	NC score	0.076133 (rank : 267)
Query Neighborhood Hits	127	Target Neighborhood Hits	759	Shared Neighborhood Hits	41
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

JAG2_MOUSE
θ value	8.99809 (rank : 123)	NC score	0.090290 (rank : 205)
Query Neighborhood Hits	127	Target Neighborhood Hits	504	Shared Neighborhood Hits	51
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

LRP11_HUMAN
θ value	8.99809 (rank : 124)	NC score	0.240256 (rank : 36)
Query Neighborhood Hits	127	Target Neighborhood Hits	82	Shared Neighborhood Hits	53
SwissProt Accessions	Q86VZ4, Q5VYC0, Q96SN6	Gene names	LRP11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

RUNX3_HUMAN
θ value	8.99809 (rank : 125)	NC score	0.017903 (rank : 476)
Query Neighborhood Hits	127	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	Q13761, Q12969, Q13760	Gene names	RUNX3, AML2, CBFA3, PEBP2A3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

SLIT3_HUMAN
θ value	8.99809 (rank : 126)	NC score	0.060691 (rank : 365)
Query Neighborhood Hits	127	Target Neighborhood Hits	682	Shared Neighborhood Hits	45
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

TMPS6_MOUSE
θ value	8.99809 (rank : 127)	NC score	0.167643 (rank : 63)
Query Neighborhood Hits	127	Target Neighborhood Hits	341	Shared Neighborhood Hits	58
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

ACRO_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.062368 (rank : 354)
Query Neighborhood Hits	127	Target Neighborhood Hits	291	Shared Neighborhood Hits	19
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

ACRO_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.060277 (rank : 372)
Query Neighborhood Hits	127	Target Neighborhood Hits	185	Shared Neighborhood Hits	16
SwissProt Accessions	P23578	Gene names	Acr
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

AGRIN_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.069225 (rank : 311)
Query Neighborhood Hits	127	Target Neighborhood Hits	582	Shared Neighborhood Hits	45
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

APOA_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.053697 (rank : 435)
Query Neighborhood Hits	127	Target Neighborhood Hits	221	Shared Neighborhood Hits	17
SwissProt Accessions	P08519	Gene names	LPA
Domain Architecture
Description	Apolipoprotein(a) precursor (EC 3.4.21.-) (Apo(a)) (Lp(a)).

ASTN_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.052786 (rank : 441)
Query Neighborhood Hits	127	Target Neighborhood Hits	105	Shared Neighborhood Hits	20
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

ASTN_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.055000 (rank : 423)
Query Neighborhood Hits	127	Target Neighborhood Hits	98	Shared Neighborhood Hits	20
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

BMP1_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.091094 (rank : 203)
Query Neighborhood Hits	127	Target Neighborhood Hits	233	Shared Neighborhood Hits	38
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.092160 (rank : 198)
Query Neighborhood Hits	127	Target Neighborhood Hits	236	Shared Neighborhood Hits	38
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMPER_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.056323 (rank : 406)
Query Neighborhood Hits	127	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

BSSP4_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.059281 (rank : 385)
Query Neighborhood Hits	127	Target Neighborhood Hits	176	Shared Neighborhood Hits	16
SwissProt Accessions	Q9GZN4, O43342, Q6UXE0	Gene names	PRSS22, BSSP4, PRSS26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

BSSP4_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.058301 (rank : 392)
Query Neighborhood Hits	127	Target Neighborhood Hits	179	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ER10	Gene names	Prss22, Bssp4, Prss26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

C1QR1_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.114341 (rank : 133)
Query Neighborhood Hits	127	Target Neighborhood Hits	493	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.108514 (rank : 144)
Query Neighborhood Hits	127	Target Neighborhood Hits	342	Shared Neighborhood Hits	41
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

C1RA_MOUSE
θ value	θ > 10 (rank : 141)	NC score	0.082160 (rank : 241)
Query Neighborhood Hits	127	Target Neighborhood Hits	379	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1RB_MOUSE
θ value	θ > 10 (rank : 142)	NC score	0.081960 (rank : 244)
Query Neighborhood Hits	127	Target Neighborhood Hits	380	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

C1R_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.081311 (rank : 247)
Query Neighborhood Hits	127	Target Neighborhood Hits	364	Shared Neighborhood Hits	43
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

C1S_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.072363 (rank : 289)
Query Neighborhood Hits	127	Target Neighborhood Hits	359	Shared Neighborhood Hits	43
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

C209E_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.132402 (rank : 105)
Query Neighborhood Hits	127	Target Neighborhood Hits	117	Shared Neighborhood Hits	38
SwissProt Accessions	Q91ZW7	Gene names	Cd209e
Domain Architecture
Description	CD209 antigen-like protein E (DC-SIGN-related protein 4) (DC-SIGNR4).

CD209_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.125821 (rank : 113)
Query Neighborhood Hits	127	Target Neighborhood Hits	244	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NNX6, Q96QP7, Q96QP8, Q96QP9, Q96QQ0, Q96QQ1, Q96QQ2, Q96QQ3, Q96QQ4, Q96QQ5, Q96QQ6, Q96QQ7, Q96QQ8	Gene names	CD209, CLEC4L
Domain Architecture
Description	CD209 antigen (Dendritic cell-specific ICAM-3-grabbing nonintegrin 1) (DC-SIGN1) (DC-SIGN) (C-type lectin domain family 4 member L).

CD302_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.113858 (rank : 136)
Query Neighborhood Hits	127	Target Neighborhood Hits	58	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IX05, Q15009	Gene names	CD302, CLEC13A, DCL1, KIAA0022
Domain Architecture	No domain graphic available
Description	CD302 antigen precursor (C-type lectin domain family 13 member A) (C- type lectin BIMLEC) (Type I transmembrane C-type lectin receptor DCL- 1).

CD302_MOUSE
θ value	θ > 10 (rank : 148)	NC score	0.119442 (rank : 124)
Query Neighborhood Hits	127	Target Neighborhood Hits	59	Shared Neighborhood Hits	26
SwissProt Accessions	Q9DCG2, Q78KD8, Q9D0X7	Gene names	Cd302, Clec13a
Domain Architecture	No domain graphic available
Description	CD302 antigen precursor (C-type lectin domain family 13 member A) (Type I transmembrane C-type lectin receptor DCL-1).

CD69_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.117261 (rank : 128)
Query Neighborhood Hits	127	Target Neighborhood Hits	99	Shared Neighborhood Hits	38
SwissProt Accessions	Q07108	Gene names	CD69
Domain Architecture
Description	Early activation antigen CD69 (Early T-cell activation antigen p60) (GP32/28) (Leu-23) (MLR-3) (EA1) (BL-AC/P26) (Activation inducer molecule) (AIM).

CD69_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.112905 (rank : 138)
Query Neighborhood Hits	127	Target Neighborhood Hits	92	Shared Neighborhood Hits	35
SwissProt Accessions	P37217	Gene names	Cd69
Domain Architecture	No domain graphic available
Description	Early activation antigen CD69.

CD72_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.065214 (rank : 330)
Query Neighborhood Hits	127	Target Neighborhood Hits	262	Shared Neighborhood Hits	27
SwissProt Accessions	P21855, Q64225	Gene names	Cd72, Ly-32, Lyb-2
Domain Architecture
Description	B-cell differentiation antigen CD72 (Lyb-2) (Antigen Ly-32).

CD97_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.055499 (rank : 417)
Query Neighborhood Hits	127	Target Neighborhood Hits	353	Shared Neighborhood Hits	33
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CFAD_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.052336 (rank : 446)
Query Neighborhood Hits	127	Target Neighborhood Hits	176	Shared Neighborhood Hits	16
SwissProt Accessions	P00746	Gene names	CFD, DF
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin).

CFAD_MOUSE
θ value	θ > 10 (rank : 154)	NC score	0.051674 (rank : 452)
Query Neighborhood Hits	127	Target Neighborhood Hits	177	Shared Neighborhood Hits	16
SwissProt Accessions	P03953, Q61280	Gene names	Cfd, Adn, Df
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin) (28 kDa adipocyte protein).

CHODL_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.103161 (rank : 163)
Query Neighborhood Hits	127	Target Neighborhood Hits	81	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H9P2, Q7Z798, Q7Z799, Q7Z7A0, Q9HCY3	Gene names	CHODL, C21orf68
Domain Architecture
Description	Chondrolectin precursor (Transmembrane protein MT75).

CHODL_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.097717 (rank : 180)
Query Neighborhood Hits	127	Target Neighborhood Hits	80	Shared Neighborhood Hits	29
SwissProt Accessions	Q9CXM0, Q8VI31	Gene names	Chodl
Domain Architecture
Description	Chondrolectin precursor (Transmembrane protein MT75).

CLC11_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.050386 (rank : 467)
Query Neighborhood Hits	127	Target Neighborhood Hits	57	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y240	Gene names	CLEC11A, CLECSF3, LSLCL, SCGF
Domain Architecture
Description	C-type lectin domain family 11 member A precursor (Stem cell growth factor) (Lymphocyte secreted C-type lectin) (p47) (C-type lectin superfamily member 3).

CLC14_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.050219 (rank : 470)
Query Neighborhood Hits	127	Target Neighborhood Hits	143	Shared Neighborhood Hits	22
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

CLC14_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.065318 (rank : 329)
Query Neighborhood Hits	127	Target Neighborhood Hits	120	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

CLC1A_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.103317 (rank : 162)
Query Neighborhood Hits	127	Target Neighborhood Hits	91	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NC01, Q8IUW7, Q9NZH3	Gene names	CLEC1A, CLEC1
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 1 member A (C-type lectin-like receptor 1) (CLEC-1).

CLC2B_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.104432 (rank : 159)
Query Neighborhood Hits	127	Target Neighborhood Hits	90	Shared Neighborhood Hits	34
SwissProt Accessions	Q92478, Q8IZE9, Q9BS74, Q9UQB4	Gene names	CLEC2B, AICL, CLECSF2, IFNRG1
Domain Architecture
Description	C-type lectin domain family 2 member B (C-type lectin superfamily member 2) (Activation-induced C-type lectin) (IFN-alpha2b-inducing- related protein 1) (C-type lectin domain family 2 member B).

CLC3A_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.091692 (rank : 201)
Query Neighborhood Hits	127	Target Neighborhood Hits	89	Shared Neighborhood Hits	33
SwissProt Accessions	O75596, Q6UXF5	Gene names	CLEC3A, CLECSF1
Domain Architecture
Description	C-type lectin domain family 3 member A precursor (C-type lectin superfamily member 1) (Cartilage-derived C-type lectin).

CLC3A_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.093220 (rank : 192)
Query Neighborhood Hits	127	Target Neighborhood Hits	95	Shared Neighborhood Hits	34
SwissProt Accessions	Q9EPW4	Gene names	Clec3a, Clecsf1
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 3 member A precursor (C-type lectin superfamily member 1) (Cartilage-derived C-type lectin).

CLC4A_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.131202 (rank : 106)
Query Neighborhood Hits	127	Target Neighborhood Hits	103	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QZ15, Q4VA33	Gene names	Clec4a, Clec4a2, Clecsf6, Dcir
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member A (C-type lectin superfamily member 6) (Dendritic cell immunoreceptor).

CLC4D_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.134936 (rank : 101)
Query Neighborhood Hits	127	Target Neighborhood Hits	104	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z2H6, Q8C212	Gene names	Clec4d, Clecsf8, Mcl
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member D (C-type lectin superfamily member 8) (Macrophage-restricted C-type lectin).

CLC4E_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.132901 (rank : 104)
Query Neighborhood Hits	127	Target Neighborhood Hits	104	Shared Neighborhood Hits	36
SwissProt Accessions	Q9ULY5	Gene names	CLEC4E, CLECSF9, MINCLE
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member E (C-type lectin superfamily member 9) (Macrophage-inducible C-type lectin).

CLC4F_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.064177 (rank : 338)
Query Neighborhood Hits	127	Target Neighborhood Hits	513	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N1N0	Gene names	CLEC4F, CLECSF13
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13).

CLC4F_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.093115 (rank : 193)
Query Neighborhood Hits	127	Target Neighborhood Hits	572	Shared Neighborhood Hits	37
SwissProt Accessions	P70194, Q8BLZ8	Gene names	Clec4f, Clecsf13, Kclr
Domain Architecture
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13) (Kupffer cell receptor).

CLC4G_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.128212 (rank : 110)
Query Neighborhood Hits	127	Target Neighborhood Hits	141	Shared Neighborhood Hits	36
SwissProt Accessions	Q6UXB4	Gene names	CLEC4G
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member G.

CLC4G_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.129570 (rank : 108)
Query Neighborhood Hits	127	Target Neighborhood Hits	155	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BNX1, Q5I0T7, Q8R188	Gene names	Clec4g
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member G.

CLC4K_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.120621 (rank : 122)
Query Neighborhood Hits	127	Target Neighborhood Hits	172	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UJ71	Gene names	CD207, CLEC4K
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member K (Langerin) (CD207 antigen).

CLC4K_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.115627 (rank : 130)
Query Neighborhood Hits	127	Target Neighborhood Hits	165	Shared Neighborhood Hits	36
SwissProt Accessions	Q8VBX4, Q8R442	Gene names	Cd207, Clec4k
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member K (Langerin) (CD207 antigen).

CLC5A_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.105437 (rank : 154)
Query Neighborhood Hits	127	Target Neighborhood Hits	90	Shared Neighborhood Hits	34
SwissProt Accessions	Q9R007, Q3UV97, Q8BL24	Gene names	Clec5a, Clecsf5, Mdl1
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 5 member A (C-type lectin superfamily member 5) (Myeloid DAP12-associating lectin protein) (MDL-1).

CLC9A_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.108015 (rank : 146)
Query Neighborhood Hits	127	Target Neighborhood Hits	95	Shared Neighborhood Hits	36
SwissProt Accessions	Q6UXN8	Gene names	CLEC9A
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 9 member A.

CLC9A_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.105399 (rank : 155)
Query Neighborhood Hits	127	Target Neighborhood Hits	97	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BRU4	Gene names	Clec9a
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 9 member A.

CLCR_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.058522 (rank : 390)
Query Neighborhood Hits	127	Target Neighborhood Hits	177	Shared Neighborhood Hits	16
SwissProt Accessions	Q99895, O00765, Q9NUH5	Gene names	CTRC, CLCR
Domain Architecture
Description	Caldecrin precursor (EC 3.4.21.2) (Chymotrypsin C).

CO2_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.050371 (rank : 468)
Query Neighborhood Hits	127	Target Neighborhood Hits	258	Shared Neighborhood Hits	21
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO2_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.053267 (rank : 438)
Query Neighborhood Hits	127	Target Neighborhood Hits	250	Shared Neighborhood Hits	21
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO7_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.135457 (rank : 100)
Query Neighborhood Hits	127	Target Neighborhood Hits	278	Shared Neighborhood Hits	59
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO8A_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.168508 (rank : 62)
Query Neighborhood Hits	127	Target Neighborhood Hits	200	Shared Neighborhood Hits	58
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO9_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.247139 (rank : 33)
Query Neighborhood Hits	127	Target Neighborhood Hits	147	Shared Neighborhood Hits	59
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

CO9_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.219311 (rank : 42)
Query Neighborhood Hits	127	Target Neighborhood Hits	153	Shared Neighborhood Hits	59
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

CR001_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.162637 (rank : 65)
Query Neighborhood Hits	127	Target Neighborhood Hits	68	Shared Neighborhood Hits	45
SwissProt Accessions	O15165, O15166, O15167, O15168, Q6NXP3	Gene names	C18orf1
Domain Architecture
Description	Protein C18orf1.

CR001_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.160027 (rank : 70)
Query Neighborhood Hits	127	Target Neighborhood Hits	67	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BWJ4	Gene names	D18Ertd653e
Domain Architecture	No domain graphic available
Description	Protein C18orf1 homolog.

CRDL1_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.054403 (rank : 427)
Query Neighborhood Hits	127	Target Neighborhood Hits	75	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BU40, Q9Y3H7	Gene names	CHRDL1, NRLN1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CRDL1_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.054341 (rank : 428)
Query Neighborhood Hits	127	Target Neighborhood Hits	81	Shared Neighborhood Hits	12
SwissProt Accessions	Q920C1, Q924K0, Q9EPZ9	Gene names	Chrdl1, Ng1, Nrln1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CREL1_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.080236 (rank : 253)
Query Neighborhood Hits	127	Target Neighborhood Hits	441	Shared Neighborhood Hits	33
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.079620 (rank : 254)
Query Neighborhood Hits	127	Target Neighborhood Hits	524	Shared Neighborhood Hits	35
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CRUM1_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.080365 (rank : 252)
Query Neighborhood Hits	127	Target Neighborhood Hits	457	Shared Neighborhood Hits	45
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM1_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.077329 (rank : 262)
Query Neighborhood Hits	127	Target Neighborhood Hits	444	Shared Neighborhood Hits	48
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CRUM2_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.072293 (rank : 291)
Query Neighborhood Hits	127	Target Neighborhood Hits	453	Shared Neighborhood Hits	40
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

CS1A_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.073339 (rank : 286)
Query Neighborhood Hits	127	Target Neighborhood Hits	360	Shared Neighborhood Hits	44
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CS1B_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.075268 (rank : 274)
Query Neighborhood Hits	127	Target Neighborhood Hits	361	Shared Neighborhood Hits	44
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

CTRB1_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.058487 (rank : 391)
Query Neighborhood Hits	127	Target Neighborhood Hits	176	Shared Neighborhood Hits	16
SwissProt Accessions	P17538	Gene names	CTRB1, CTRB
Domain Architecture
Description	Chymotrypsinogen B precursor (EC 3.4.21.1) [Contains: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C].

CTRL_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.058558 (rank : 389)
Query Neighborhood Hits	127	Target Neighborhood Hits	179	Shared Neighborhood Hits	16
SwissProt Accessions	P40313	Gene names	CTRL, CTRL1
Domain Architecture
Description	Chymotrypsin-like protease CTRL-1 precursor (EC 3.4.21.-).

CUBN_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.086532 (rank : 219)
Query Neighborhood Hits	127	Target Neighborhood Hits	482	Shared Neighborhood Hits	51
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CUBN_MOUSE
θ value	θ > 10 (rank : 197)	NC score	0.094649 (rank : 188)
Query Neighborhood Hits	127	Target Neighborhood Hits	477	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

DESC4_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.063169 (rank : 348)
Query Neighborhood Hits	127	Target Neighborhood Hits	176	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BZ10, Q8BZ04	Gene names	Desc4
Domain Architecture	No domain graphic available
Description	Serine protease DESC4 precursor (EC 3.4.21.-) [Contains: Serine protease DESC4 non-catalytic chain; Serine protease DESC4 catalytic chain].

DLK_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.070787 (rank : 299)
Query Neighborhood Hits	127	Target Neighborhood Hits	401	Shared Neighborhood Hits	41
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLK_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.068082 (rank : 315)
Query Neighborhood Hits	127	Target Neighborhood Hits	374	Shared Neighborhood Hits	37
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

DLL1_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.083194 (rank : 232)
Query Neighborhood Hits	127	Target Neighborhood Hits	455	Shared Neighborhood Hits	52
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DLL1_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.084326 (rank : 228)
Query Neighborhood Hits	127	Target Neighborhood Hits	456	Shared Neighborhood Hits	48
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

DLL3_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.068808 (rank : 312)
Query Neighborhood Hits	127	Target Neighborhood Hits	419	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DLL3_MOUSE
θ value	θ > 10 (rank : 204)	NC score	0.064461 (rank : 335)
Query Neighborhood Hits	127	Target Neighborhood Hits	399	Shared Neighborhood Hits	38
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

DLL4_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.076315 (rank : 265)
Query Neighborhood Hits	127	Target Neighborhood Hits	435	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL4_MOUSE
θ value	θ > 10 (rank : 206)	NC score	0.074404 (rank : 280)
Query Neighborhood Hits	127	Target Neighborhood Hits	440	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DNER_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.065473 (rank : 328)
Query Neighborhood Hits	127	Target Neighborhood Hits	460	Shared Neighborhood Hits	40
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DNER_MOUSE
θ value	θ > 10 (rank : 208)	NC score	0.059671 (rank : 377)
Query Neighborhood Hits	127	Target Neighborhood Hits	413	Shared Neighborhood Hits	38
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

EDIL3_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.061734 (rank : 357)
Query Neighborhood Hits	127	Target Neighborhood Hits	292	Shared Neighborhood Hits	32
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
θ value	θ > 10 (rank : 210)	NC score	0.054216 (rank : 432)
Query Neighborhood Hits	127	Target Neighborhood Hits	317	Shared Neighborhood Hits	28
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EGFL7_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.086236 (rank : 221)
Query Neighborhood Hits	127	Target Neighborhood Hits	325	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL7_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.066427 (rank : 324)
Query Neighborhood Hits	127	Target Neighborhood Hits	287	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EGFL8_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.078702 (rank : 257)
Query Neighborhood Hits	127	Target Neighborhood Hits	270	Shared Neighborhood Hits	32
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL8_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.073857 (rank : 283)
Query Neighborhood Hits	127	Target Neighborhood Hits	266	Shared Neighborhood Hits	31
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EGFL9_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.059230 (rank : 386)
Query Neighborhood Hits	127	Target Neighborhood Hits	365	Shared Neighborhood Hits	36
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
θ value	θ > 10 (rank : 216)	NC score	0.060221 (rank : 373)
Query Neighborhood Hits	127	Target Neighborhood Hits	379	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

EGF_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.232775 (rank : 38)
Query Neighborhood Hits	127	Target Neighborhood Hits	343	Shared Neighborhood Hits	40
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EGF_MOUSE
θ value	θ > 10 (rank : 218)	NC score	0.225850 (rank : 39)
Query Neighborhood Hits	127	Target Neighborhood Hits	358	Shared Neighborhood Hits	40
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

ELA1_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.054470 (rank : 426)
Query Neighborhood Hits	127	Target Neighborhood Hits	178	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UNI1, Q5MLF0, Q6DJT0, Q6ISM6	Gene names	ELA1
Domain Architecture
Description	Elastase-1 precursor (EC 3.4.21.36).

ELA2A_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.056508 (rank : 403)
Query Neighborhood Hits	127	Target Neighborhood Hits	180	Shared Neighborhood Hits	16
SwissProt Accessions	P08217, Q14243	Gene names	ELA2A
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71).

ELA2A_MOUSE
θ value	θ > 10 (rank : 221)	NC score	0.057105 (rank : 396)
Query Neighborhood Hits	127	Target Neighborhood Hits	178	Shared Neighborhood Hits	16
SwissProt Accessions	P05208	Gene names	Ela2a, Ela-2, Ela2
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71) (Elastase-2).

ELA2B_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.056172 (rank : 409)
Query Neighborhood Hits	127	Target Neighborhood Hits	178	Shared Neighborhood Hits	16
SwissProt Accessions	P08218	Gene names	ELA2B
Domain Architecture
Description	Elastase-2B precursor (EC 3.4.21.71).

ELA3A_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.055975 (rank : 413)
Query Neighborhood Hits	127	Target Neighborhood Hits	173	Shared Neighborhood Hits	16
SwissProt Accessions	P09093, Q9BRW4	Gene names	ELA3A, ELA3
Domain Architecture
Description	Elastase-3A precursor (EC 3.4.21.70) (Elastase IIIA) (Protease E).

ELA3B_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.056219 (rank : 408)
Query Neighborhood Hits	127	Target Neighborhood Hits	175	Shared Neighborhood Hits	16
SwissProt Accessions	P08861, P11423, Q5VU28, Q5VU29, Q5VU30	Gene names	ELA3B
Domain Architecture
Description	Elastase-3B precursor (EC 3.4.21.70) (Elastase IIIB) (Protease E).

ELTD1_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.050438 (rank : 466)
Query Neighborhood Hits	127	Target Neighborhood Hits	288	Shared Neighborhood Hits	25
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

EMBP_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.067728 (rank : 317)
Query Neighborhood Hits	127	Target Neighborhood Hits	42	Shared Neighborhood Hits	15
SwissProt Accessions	P13727, Q14227	Gene names	PRG2, MBP
Domain Architecture
Description	Eosinophil granule major basic protein precursor (MBP) (EMBP) (Pregnancy-associated major basic protein) (Proteoglycan 2, bone marrow) (BMPG).

EMBP_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.064156 (rank : 339)
Query Neighborhood Hits	127	Target Neighborhood Hits	45	Shared Neighborhood Hits	14
SwissProt Accessions	Q61878	Gene names	Prg2, Mbp-1
Domain Architecture
Description	Eosinophil granule major basic protein precursor (MBP) (Proteoglycan 2, bone marrow).

EMR1_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.061395 (rank : 360)
Query Neighborhood Hits	127	Target Neighborhood Hits	382	Shared Neighborhood Hits	44
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EMR1_MOUSE
θ value	θ > 10 (rank : 229)	NC score	0.052218 (rank : 447)
Query Neighborhood Hits	127	Target Neighborhood Hits	349	Shared Neighborhood Hits	36
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EMR2_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.056106 (rank : 411)
Query Neighborhood Hits	127	Target Neighborhood Hits	345	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

FA10_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.085915 (rank : 222)
Query Neighborhood Hits	127	Target Neighborhood Hits	431	Shared Neighborhood Hits	49
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA10_MOUSE
θ value	θ > 10 (rank : 232)	NC score	0.086531 (rank : 220)
Query Neighborhood Hits	127	Target Neighborhood Hits	435	Shared Neighborhood Hits	51
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA11_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.060719 (rank : 364)
Query Neighborhood Hits	127	Target Neighborhood Hits	178	Shared Neighborhood Hits	16
SwissProt Accessions	P03951, Q9Y495	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

FA11_MOUSE
θ value	θ > 10 (rank : 234)	NC score	0.061017 (rank : 361)
Query Neighborhood Hits	127	Target Neighborhood Hits	180	Shared Neighborhood Hits	16
SwissProt Accessions	Q91Y47	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

FA12_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.082892 (rank : 234)
Query Neighborhood Hits	127	Target Neighborhood Hits	425	Shared Neighborhood Hits	37
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

FA7_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.081101 (rank : 249)
Query Neighborhood Hits	127	Target Neighborhood Hits	404	Shared Neighborhood Hits	45
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

FA7_MOUSE
θ value	θ > 10 (rank : 237)	NC score	0.080744 (rank : 250)
Query Neighborhood Hits	127	Target Neighborhood Hits	374	Shared Neighborhood Hits	42
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

FA9_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.088538 (rank : 213)
Query Neighborhood Hits	127	Target Neighborhood Hits	421	Shared Neighborhood Hits	51
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

FBLN1_HUMAN
θ value	θ > 10 (rank : 239)	NC score	0.095098 (rank : 186)
Query Neighborhood Hits	127	Target Neighborhood Hits	324	Shared Neighborhood Hits	41
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN1_MOUSE
θ value	θ > 10 (rank : 240)	NC score	0.098678 (rank : 174)
Query Neighborhood Hits	127	Target Neighborhood Hits	329	Shared Neighborhood Hits	41
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN2_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.099345 (rank : 173)
Query Neighborhood Hits	127	Target Neighborhood Hits	392	Shared Neighborhood Hits	49
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_MOUSE
θ value	θ > 10 (rank : 242)	NC score	0.098243 (rank : 178)
Query Neighborhood Hits	127	Target Neighborhood Hits	505	Shared Neighborhood Hits	51
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN3_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.080442 (rank : 251)
Query Neighborhood Hits	127	Target Neighborhood Hits	293	Shared Neighborhood Hits	37
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN3_MOUSE
θ value	θ > 10 (rank : 244)	NC score	0.076042 (rank : 269)
Query Neighborhood Hits	127	Target Neighborhood Hits	279	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN4_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.083106 (rank : 233)
Query Neighborhood Hits	127	Target Neighborhood Hits	278	Shared Neighborhood Hits	36
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	θ > 10 (rank : 246)	NC score	0.081869 (rank : 246)
Query Neighborhood Hits	127	Target Neighborhood Hits	270	Shared Neighborhood Hits	34
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.090647 (rank : 204)
Query Neighborhood Hits	127	Target Neighborhood Hits	329	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
θ value	θ > 10 (rank : 248)	NC score	0.089059 (rank : 210)
Query Neighborhood Hits	127	Target Neighborhood Hits	317	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBN1_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.098150 (rank : 179)
Query Neighborhood Hits	127	Target Neighborhood Hits	557	Shared Neighborhood Hits	50
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.096717 (rank : 181)
Query Neighborhood Hits	127	Target Neighborhood Hits	560	Shared Neighborhood Hits	50
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
θ value	θ > 10 (rank : 251)	NC score	0.096037 (rank : 182)
Query Neighborhood Hits	127	Target Neighborhood Hits	549	Shared Neighborhood Hits	50
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.098453 (rank : 176)
Query Neighborhood Hits	127	Target Neighborhood Hits	543	Shared Neighborhood Hits	48
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FCER2_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.129678 (rank : 107)
Query Neighborhood Hits	127	Target Neighborhood Hits	213	Shared Neighborhood Hits	39
SwissProt Accessions	P06734	Gene names	FCER2, IGEBF
Domain Architecture
Description	Low affinity immunoglobulin epsilon Fc receptor (Lymphocyte IgE receptor) (Fc-epsilon-RII) (BLAST-2) (Immunoglobulin E-binding factor) (CD23 antigen) [Contains: Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form].

FCER2_MOUSE
θ value	θ > 10 (rank : 254)	NC score	0.124191 (rank : 114)
Query Neighborhood Hits	127	Target Neighborhood Hits	392	Shared Neighborhood Hits	39
SwissProt Accessions	P20693, Q61556, Q61557	Gene names	Fcer2, Fcer2a
Domain Architecture
Description	Low affinity immunoglobulin epsilon Fc receptor (Lymphocyte IGE receptor) (Fc-epsilon-RII) (CD23 antigen).

FRAS1_MOUSE
θ value	θ > 10 (rank : 255)	NC score	0.071793 (rank : 293)
Query Neighborhood Hits	127	Target Neighborhood Hits	747	Shared Neighborhood Hits	37
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FREM1_MOUSE
θ value	θ > 10 (rank : 256)	NC score	0.075259 (rank : 275)
Query Neighborhood Hits	127	Target Neighborhood Hits	163	Shared Neighborhood Hits	36
SwissProt Accessions	Q684R7, Q5H8C2, Q5M7B3, Q8C732	Gene names	Frem1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

GAS6_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.105217 (rank : 156)
Query Neighborhood Hits	127	Target Neighborhood Hits	348	Shared Neighborhood Hits	40
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GAS6_MOUSE
θ value	θ > 10 (rank : 258)	NC score	0.108890 (rank : 142)
Query Neighborhood Hits	127	Target Neighborhood Hits	343	Shared Neighborhood Hits	35
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GLU2B_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.155801 (rank : 75)
Query Neighborhood Hits	127	Target Neighborhood Hits	377	Shared Neighborhood Hits	43
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

GLU2B_MOUSE
θ value	θ > 10 (rank : 260)	NC score	0.145290 (rank : 92)
Query Neighborhood Hits	127	Target Neighborhood Hits	357	Shared Neighborhood Hits	40
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

GRAM_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.055691 (rank : 416)
Query Neighborhood Hits	127	Target Neighborhood Hits	174	Shared Neighborhood Hits	16
SwissProt Accessions	P51124	Gene names	GZMM, MET1
Domain Architecture
Description	Granzyme M precursor (EC 3.4.21.-) (Met-ase) (Natural killer cell granular protease) (HU-Met-1) (Met-1 serine protease).

GRN_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.118982 (rank : 126)
Query Neighborhood Hits	127	Target Neighborhood Hits	268	Shared Neighborhood Hits	38
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

GRN_MOUSE
θ value	θ > 10 (rank : 263)	NC score	0.085288 (rank : 224)
Query Neighborhood Hits	127	Target Neighborhood Hits	248	Shared Neighborhood Hits	34
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

HABP2_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.070145 (rank : 305)
Query Neighborhood Hits	127	Target Neighborhood Hits	431	Shared Neighborhood Hits	33
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HABP2_MOUSE
θ value	θ > 10 (rank : 265)	NC score	0.074961 (rank : 277)
Query Neighborhood Hits	127	Target Neighborhood Hits	445	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HEPS_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.062466 (rank : 353)
Query Neighborhood Hits	127	Target Neighborhood Hits	178	Shared Neighborhood Hits	16
SwissProt Accessions	P05981	Gene names	HPN, TMPRSS1
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) (Transmembrane protease, serine 1) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

HEPS_MOUSE
θ value	θ > 10 (rank : 267)	NC score	0.062813 (rank : 351)
Query Neighborhood Hits	127	Target Neighborhood Hits	178	Shared Neighborhood Hits	16
SwissProt Accessions	O35453, Q9CW97	Gene names	Hpn
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

HGFA_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.083460 (rank : 230)
Query Neighborhood Hits	127	Target Neighborhood Hits	436	Shared Neighborhood Hits	43
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HGFA_MOUSE
θ value	θ > 10 (rank : 269)	NC score	0.082688 (rank : 236)
Query Neighborhood Hits	127	Target Neighborhood Hits	419	Shared Neighborhood Hits	44
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HGFL_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.051278 (rank : 456)
Query Neighborhood Hits	127	Target Neighborhood Hits	190	Shared Neighborhood Hits	16
SwissProt Accessions	P26927, Q13350, Q14870	Gene names	MST1, HGFL
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) (Macrophage-stimulating protein) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

HGFL_MOUSE
θ value	θ > 10 (rank : 271)	NC score	0.051248 (rank : 457)
Query Neighborhood Hits	127	Target Neighborhood Hits	188	Shared Neighborhood Hits	16
SwissProt Accessions	P26928	Gene names	Mst1, Hgfl
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

HMCN1_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.068393 (rank : 313)
Query Neighborhood Hits	127	Target Neighborhood Hits	983	Shared Neighborhood Hits	49
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

HPTR_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.052133 (rank : 449)
Query Neighborhood Hits	127	Target Neighborhood Hits	166	Shared Neighborhood Hits	16
SwissProt Accessions	P00739, Q7LE20, Q92658, Q92659, Q9ULB0	Gene names	HPR
Domain Architecture
Description	Haptoglobin-related protein precursor.

HPT_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.052869 (rank : 440)
Query Neighborhood Hits	127	Target Neighborhood Hits	184	Shared Neighborhood Hits	17
SwissProt Accessions	P00738, P00737, Q2PP15, Q3B7J0, Q6LBY9	Gene names	HP
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

HPT_MOUSE
θ value	θ > 10 (rank : 275)	NC score	0.054551 (rank : 424)
Query Neighborhood Hits	127	Target Neighborhood Hits	178	Shared Neighborhood Hits	16
SwissProt Accessions	Q61646	Gene names	Hp
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

JAG1_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.082323 (rank : 238)
Query Neighborhood Hits	127	Target Neighborhood Hits	514	Shared Neighborhood Hits	50
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
θ value	θ > 10 (rank : 277)	NC score	0.083748 (rank : 229)
Query Neighborhood Hits	127	Target Neighborhood Hits	518	Shared Neighborhood Hits	51
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG2_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.088185 (rank : 215)
Query Neighborhood Hits	127	Target Neighborhood Hits	491	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

KLK13_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.051498 (rank : 454)
Query Neighborhood Hits	127	Target Neighborhood Hits	179	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UKR3, Q9Y433	Gene names	KLK13, KLKL4
Domain Architecture
Description	Kallikrein-13 precursor (EC 3.4.21.-) (Kallikrein-like protein 4) (KLK-L4).

KLK14_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.051201 (rank : 459)
Query Neighborhood Hits	127	Target Neighborhood Hits	179	Shared Neighborhood Hits	16
SwissProt Accessions	Q9P0G3	Gene names	KLK14, KLKL6
Domain Architecture
Description	Kallikrein-14 precursor (EC 3.4.21.-) (Kallikrein-like protein 6) (KLK-L6).

KLK15_HUMAN
θ value	θ > 10 (rank : 281)	NC score	0.051181 (rank : 460)
Query Neighborhood Hits	127	Target Neighborhood Hits	180	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H2R5, Q15358, Q9H2R3, Q9H2R4, Q9H2R6, Q9HBG9	Gene names	KLK15
Domain Architecture
Description	Kallikrein-15 precursor (EC 3.4.21.-) (ACO protease).

KLK4_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.051369 (rank : 455)
Query Neighborhood Hits	127	Target Neighborhood Hits	175	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y5K2, Q4VB16, Q9GZL6, Q9UBJ6	Gene names	KLK4, EMSP1, PRSS17, PSTS
Domain Architecture
Description	Kallikrein-4 precursor (EC 3.4.21.-) (Prostase) (Kallikrein-like protein 1) (KLK-L1) (Enamel matrix serine proteinase 1).

KLK5_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.051744 (rank : 451)
Query Neighborhood Hits	127	Target Neighborhood Hits	182	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y337, Q9HBG8	Gene names	KLK5, SCTE
Domain Architecture
Description	Kallikrein-5 precursor (EC 3.4.21.-) (Stratum corneum tryptic enzyme) (Kallikrein-like protein 2) (KLK-L2).

KLK6_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.051203 (rank : 458)
Query Neighborhood Hits	127	Target Neighborhood Hits	175	Shared Neighborhood Hits	16
SwissProt Accessions	Q92876	Gene names	KLK6, PRSS18, PRSS9
Domain Architecture
Description	Kallikrein-6 precursor (EC 3.4.21.-) (Protease M) (Neurosin) (Zyme) (SP59).

KLK7_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.050646 (rank : 464)
Query Neighborhood Hits	127	Target Neighborhood Hits	175	Shared Neighborhood Hits	16
SwissProt Accessions	Q91VE3, Q9R048	Gene names	Klk7, Prss6, Scce
Domain Architecture	No domain graphic available
Description	Kallikrein-7 precursor (EC 3.4.21.-) (Stratum corneum chymotryptic enzyme) (Thymopsin).

KLKB1_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.060571 (rank : 366)
Query Neighborhood Hits	127	Target Neighborhood Hits	183	Shared Neighborhood Hits	16
SwissProt Accessions	P03952	Gene names	KLKB1, KLK3
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

KLKB1_MOUSE
θ value	θ > 10 (rank : 287)	NC score	0.061649 (rank : 359)
Query Neighborhood Hits	127	Target Neighborhood Hits	177	Shared Neighborhood Hits	16
SwissProt Accessions	P26262	Gene names	Klkb1, Klk3, Pk
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

KLRA3_MOUSE
θ value	θ > 10 (rank : 288)	NC score	0.070337 (rank : 302)
Query Neighborhood Hits	127	Target Neighborhood Hits	90	Shared Neighborhood Hits	34
SwissProt Accessions	Q64329, Q61154, Q64257	Gene names	Klra3, Ly-49c, Ly49C
Domain Architecture
Description	Killer cell lectin-like receptor 3 (T-cell surface glycoprotein Ly- 49C) (Ly49-C antigen) (Lymphocyte antigen 49C) (5E6).

KLRA4_MOUSE
θ value	θ > 10 (rank : 289)	NC score	0.067022 (rank : 320)
Query Neighborhood Hits	127	Target Neighborhood Hits	91	Shared Neighborhood Hits	34
SwissProt Accessions	Q60651, O78026, Q9EPA5	Gene names	Klra4, Ly-49d, Ly49-d, Ly49d
Domain Architecture
Description	Killer cell lectin-like receptor 4 (T-cell surface glycoprotein Ly- 49D) (Ly49-D antigen) (Lymphocyte antigen 49D).

KLRA5_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.068166 (rank : 314)
Query Neighborhood Hits	127	Target Neighborhood Hits	88	Shared Neighborhood Hits	35
SwissProt Accessions	Q60652	Gene names	Klra5, Ly-49e, Ly49-e, Ly49e
Domain Architecture
Description	Killer cell lectin-like receptor 5 (T-cell surface glycoprotein Ly- 49E) (Ly49-E antigen) (Lymphocyte antigen 49E).

KLRA6_MOUSE
θ value	θ > 10 (rank : 291)	NC score	0.064447 (rank : 336)
Query Neighborhood Hits	127	Target Neighborhood Hits	91	Shared Neighborhood Hits	34
SwissProt Accessions	Q60653	Gene names	Klra6, Ly-49f, Ly49-f, Ly49F
Domain Architecture
Description	Killer cell lectin-like receptor 6 (T-cell surface glycoprotein Ly- 49F) (Ly49-F antigen) (Lymphocyte antigen 49F).

KLRA7_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.067005 (rank : 321)
Query Neighborhood Hits	127	Target Neighborhood Hits	89	Shared Neighborhood Hits	34
SwissProt Accessions	Q60654, Q60655, Q60656, Q60683	Gene names	Klra7, Ly-49g, Ly49-g, Ly49g, Ly49g4
Domain Architecture
Description	Killer cell lectin-like receptor 7 (T-cell surface glycoprotein Ly- 49G) (Ly49-G antigen) (Lymphocyte antigen 49G).

KLRA8_MOUSE
θ value	θ > 10 (rank : 293)	NC score	0.060410 (rank : 370)
Query Neighborhood Hits	127	Target Neighborhood Hits	90	Shared Neighborhood Hits	33
SwissProt Accessions	Q60682, O78027	Gene names	Klra8, Ly-49h, Ly49-h, Ly49H
Domain Architecture
Description	Killer cell lectin-like receptor 8 (T-cell surface glycoprotein Ly- 49H) (Ly49-H antigen) (Lymphocyte antigen 49H).

KLRBA_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.104843 (rank : 157)
Query Neighborhood Hits	127	Target Neighborhood Hits	104	Shared Neighborhood Hits	35
SwissProt Accessions	P27811	Gene names	Klrb1a, Ly55, Ly55a
Domain Architecture
Description	Natural killer cell surface protein P1-2 (NKR-P1 2) (NKR-P1.7).

KLRBC_MOUSE
θ value	θ > 10 (rank : 295)	NC score	0.106467 (rank : 151)
Query Neighborhood Hits	127	Target Neighborhood Hits	101	Shared Neighborhood Hits	34
SwissProt Accessions	P27814	Gene names	Klrb1c, Ly55-c, Ly55c
Domain Architecture
Description	Natural killer cell surface protein P1-40 (NKR-P1 40) (NKR-P1.9).

KLRD1_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.108825 (rank : 143)
Query Neighborhood Hits	127	Target Neighborhood Hits	101	Shared Neighborhood Hits	35
SwissProt Accessions	Q13241, O43321, O43773, Q9UBE3, Q9UEQ0	Gene names	KLRD1, CD94
Domain Architecture
Description	Natural killer cells antigen CD94 (NK cell receptor) (Killer cell lectin-like receptor subfamily D member 1) (KP43).

KLRF1_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.122536 (rank : 119)
Query Neighborhood Hits	127	Target Neighborhood Hits	100	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NZS2, Q96PR2, Q96PR3, Q9NZS1	Gene names	KLRF1, ML
Domain Architecture
Description	Killer cell lectin-like receptor subfamily F member 1 (Lectin-like receptor F1) (Activating coreceptor NKp80).

KR104_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.069281 (rank : 310)
Query Neighborhood Hits	127	Target Neighborhood Hits	313	Shared Neighborhood Hits	33
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR106_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.074544 (rank : 279)
Query Neighborhood Hits	127	Target Neighborhood Hits	347	Shared Neighborhood Hits	39
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR107_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.078243 (rank : 259)
Query Neighborhood Hits	127	Target Neighborhood Hits	330	Shared Neighborhood Hits	37
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR109_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.051168 (rank : 461)
Query Neighborhood Hits	127	Target Neighborhood Hits	226	Shared Neighborhood Hits	25
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR10B_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.054254 (rank : 429)
Query Neighborhood Hits	127	Target Neighborhood Hits	269	Shared Neighborhood Hits	28
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KR412_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.054226 (rank : 431)
Query Neighborhood Hits	127	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR511_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.053491 (rank : 437)
Query Neighborhood Hits	127	Target Neighborhood Hits	231	Shared Neighborhood Hits	19
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA53_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.064131 (rank : 340)
Query Neighborhood Hits	127	Target Neighborhood Hits	331	Shared Neighborhood Hits	30
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA58_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.054490 (rank : 425)
Query Neighborhood Hits	127	Target Neighborhood Hits	324	Shared Neighborhood Hits	28
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA59_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.062693 (rank : 352)
Query Neighborhood Hits	127	Target Neighborhood Hits	310	Shared Neighborhood Hits	27
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

LAMA1_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.055323 (rank : 419)
Query Neighborhood Hits	127	Target Neighborhood Hits	804	Shared Neighborhood Hits	44
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA1_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.063941 (rank : 342)
Query Neighborhood Hits	127	Target Neighborhood Hits	838	Shared Neighborhood Hits	44
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA3_MOUSE
θ value	θ > 10 (rank : 310)	NC score	0.050161 (rank : 471)
Query Neighborhood Hits	127	Target Neighborhood Hits	859	Shared Neighborhood Hits	39
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LAMA5_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.052662 (rank : 442)
Query Neighborhood Hits	127	Target Neighborhood Hits	976	Shared Neighborhood Hits	50
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMA5_MOUSE
θ value	θ > 10 (rank : 312)	NC score	0.056382 (rank : 405)
Query Neighborhood Hits	127	Target Neighborhood Hits	828	Shared Neighborhood Hits	49
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LCE3B_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.065178 (rank : 331)
Query Neighborhood Hits	127	Target Neighborhood Hits	47	Shared Neighborhood Hits	10
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

LIT1_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.117599 (rank : 127)
Query Neighborhood Hits	127	Target Neighborhood Hits	114	Shared Neighborhood Hits	36
SwissProt Accessions	P43137	Gene names	Reg1
Domain Architecture
Description	Lithostathine 1 precursor (Pancreatic stone protein 1) (PSP) (Pancreatic thread protein 1) (PTP) (Islet of Langerhans regenerating protein 1) (REG 1).

LIT2_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.122906 (rank : 118)
Query Neighborhood Hits	127	Target Neighborhood Hits	111	Shared Neighborhood Hits	35
SwissProt Accessions	Q08731	Gene names	Reg2
Domain Architecture
Description	Lithostathine 2 precursor (Pancreatic stone protein 2) (PSP) (Pancreatic thread protein 2) (PTP) (Islet of Langerhans regenerating protein 2) (REG 2).

LTB1L_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.094983 (rank : 187)
Query Neighborhood Hits	127	Target Neighborhood Hits	553	Shared Neighborhood Hits	52
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.089257 (rank : 207)
Query Neighborhood Hits	127	Target Neighborhood Hits	514	Shared Neighborhood Hits	49
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.095112 (rank : 185)
Query Neighborhood Hits	127	Target Neighborhood Hits	502	Shared Neighborhood Hits	49
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	θ > 10 (rank : 319)	NC score	0.089283 (rank : 206)
Query Neighborhood Hits	127	Target Neighborhood Hits	479	Shared Neighborhood Hits	46
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP2_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.091420 (rank : 202)
Query Neighborhood Hits	127	Target Neighborhood Hits	552	Shared Neighborhood Hits	47
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP2_MOUSE
θ value	θ > 10 (rank : 321)	NC score	0.083380 (rank : 231)
Query Neighborhood Hits	127	Target Neighborhood Hits	617	Shared Neighborhood Hits	46
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP3_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.082053 (rank : 242)
Query Neighborhood Hits	127	Target Neighborhood Hits	502	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP3_MOUSE
θ value	θ > 10 (rank : 323)	NC score	0.082541 (rank : 237)
Query Neighborhood Hits	127	Target Neighborhood Hits	475	Shared Neighborhood Hits	48
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP4_MOUSE
θ value	θ > 10 (rank : 324)	NC score	0.088842 (rank : 212)
Query Neighborhood Hits	127	Target Neighborhood Hits	607	Shared Neighborhood Hits	47
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

LY49A_MOUSE
θ value	θ > 10 (rank : 325)	NC score	0.066746 (rank : 323)
Query Neighborhood Hits	127	Target Neighborhood Hits	91	Shared Neighborhood Hits	34
SwissProt Accessions	P20937	Gene names	Klra1, Ly-49, Ly-49a, Ly49, Ly49A
Domain Architecture
Description	T-cell surface glycoprotein YE1/48 (T lymphocyte antigen A1) (Ly49-A antigen) (Lymphocyte antigen 49A).

LYAM1_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.075321 (rank : 272)
Query Neighborhood Hits	127	Target Neighborhood Hits	315	Shared Neighborhood Hits	42
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM1_MOUSE
θ value	θ > 10 (rank : 327)	NC score	0.076877 (rank : 263)
Query Neighborhood Hits	127	Target Neighborhood Hits	332	Shared Neighborhood Hits	46
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM2_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.060925 (rank : 362)
Query Neighborhood Hits	127	Target Neighborhood Hits	394	Shared Neighborhood Hits	48
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM2_MOUSE
θ value	θ > 10 (rank : 329)	NC score	0.064644 (rank : 334)
Query Neighborhood Hits	127	Target Neighborhood Hits	420	Shared Neighborhood Hits	51
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM3_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.059664 (rank : 378)
Query Neighborhood Hits	127	Target Neighborhood Hits	378	Shared Neighborhood Hits	52
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LYAM3_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.054238 (rank : 430)
Query Neighborhood Hits	127	Target Neighborhood Hits	390	Shared Neighborhood Hits	50
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MASP1_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.081884 (rank : 245)
Query Neighborhood Hits	127	Target Neighborhood Hits	369	Shared Neighborhood Hits	44
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

MASP1_MOUSE
θ value	θ > 10 (rank : 333)	NC score	0.079102 (rank : 256)
Query Neighborhood Hits	127	Target Neighborhood Hits	364	Shared Neighborhood Hits	42
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

MASP2_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.082322 (rank : 239)
Query Neighborhood Hits	127	Target Neighborhood Hits	364	Shared Neighborhood Hits	44
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MASP2_MOUSE
θ value	θ > 10 (rank : 335)	NC score	0.078299 (rank : 258)
Query Neighborhood Hits	127	Target Neighborhood Hits	382	Shared Neighborhood Hits	44
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MATN2_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.085738 (rank : 223)
Query Neighborhood Hits	127	Target Neighborhood Hits	365	Shared Neighborhood Hits	39
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

MATN2_MOUSE
θ value	θ > 10 (rank : 337)	NC score	0.077630 (rank : 261)
Query Neighborhood Hits	127	Target Neighborhood Hits	356	Shared Neighborhood Hits	38
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MATN3_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.082245 (rank : 240)
Query Neighborhood Hits	127	Target Neighborhood Hits	268	Shared Neighborhood Hits	27
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_MOUSE
θ value	θ > 10 (rank : 339)	NC score	0.079565 (rank : 255)
Query Neighborhood Hits	127	Target Neighborhood Hits	261	Shared Neighborhood Hits	28
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.084884 (rank : 225)
Query Neighborhood Hits	127	Target Neighborhood Hits	287	Shared Neighborhood Hits	33
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MATN4_MOUSE
θ value	θ > 10 (rank : 341)	NC score	0.081181 (rank : 248)
Query Neighborhood Hits	127	Target Neighborhood Hits	277	Shared Neighborhood Hits	31
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

MBL1_MOUSE
θ value	θ > 10 (rank : 342)	NC score	0.075277 (rank : 273)
Query Neighborhood Hits	127	Target Neighborhood Hits	147	Shared Neighborhood Hits	28
SwissProt Accessions	P39039	Gene names	Mbl1
Domain Architecture
Description	Mannose-binding protein A precursor (MBP-A) (Mannan-binding protein) (Ra-reactive factor polysaccharide-binding component p28B polypeptide) (RaRF p28B).

MBL2_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.069812 (rank : 306)
Query Neighborhood Hits	127	Target Neighborhood Hits	161	Shared Neighborhood Hits	29
SwissProt Accessions	P11226, Q86SI4, Q96KE4, Q96TF7, Q96TF8, Q96TF9	Gene names	MBL2, MBL
Domain Architecture
Description	Mannose-binding protein C precursor (MBP-C) (MBP1) (Mannan-binding protein) (Mannose-binding lectin).

MBL2_MOUSE
θ value	θ > 10 (rank : 344)	NC score	0.075600 (rank : 271)
Query Neighborhood Hits	127	Target Neighborhood Hits	148	Shared Neighborhood Hits	29
SwissProt Accessions	P41317	Gene names	Mbl2
Domain Architecture
Description	Mannose-binding protein C precursor (MBP-C) (Mannan-binding protein) (RA-reactive factor P28A subunit) (RARF/P28A).

MCPT6_MOUSE
θ value	θ > 10 (rank : 345)	NC score	0.057864 (rank : 393)
Query Neighborhood Hits	127	Target Neighborhood Hits	175	Shared Neighborhood Hits	16
SwissProt Accessions	P21845, Q61962	Gene names	Mcpt6
Domain Architecture
Description	Mast cell protease 6 precursor (EC 3.4.21.59) (MMCP-6) (Tryptase).

MEGF6_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.093657 (rank : 191)
Query Neighborhood Hits	127	Target Neighborhood Hits	671	Shared Neighborhood Hits	50
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

MEGF8_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.071480 (rank : 294)
Query Neighborhood Hits	127	Target Neighborhood Hits	528	Shared Neighborhood Hits	49
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.072910 (rank : 287)
Query Neighborhood Hits	127	Target Neighborhood Hits	520	Shared Neighborhood Hits	49
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF9_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.050362 (rank : 469)
Query Neighborhood Hits	127	Target Neighborhood Hits	557	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MMGL_MOUSE
θ value	θ > 10 (rank : 350)	NC score	0.126329 (rank : 112)
Query Neighborhood Hits	127	Target Neighborhood Hits	270	Shared Neighborhood Hits	37
SwissProt Accessions	P49300	Gene names	Mgl1, Mgl
Domain Architecture
Description	Macrophage asialoglycoprotein-binding protein 1 (M-ASGP-BP) (Macrophage galactose/N-acetylgalactosamine-specific lectin) (MMGL).

NELL1_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.084780 (rank : 226)
Query Neighborhood Hits	127	Target Neighborhood Hits	451	Shared Neighborhood Hits	48
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NELL2_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.088893 (rank : 211)
Query Neighborhood Hits	127	Target Neighborhood Hits	449	Shared Neighborhood Hits	49
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
θ value	θ > 10 (rank : 353)	NC score	0.087302 (rank : 217)
Query Neighborhood Hits	127	Target Neighborhood Hits	436	Shared Neighborhood Hits	46
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NETO1_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.098287 (rank : 177)
Query Neighborhood Hits	127	Target Neighborhood Hits	110	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
θ value	θ > 10 (rank : 355)	NC score	0.098585 (rank : 175)
Query Neighborhood Hits	127	Target Neighborhood Hits	109	Shared Neighborhood Hits	47
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO2_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.100121 (rank : 170)
Query Neighborhood Hits	127	Target Neighborhood Hits	109	Shared Neighborhood Hits	45
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
θ value	θ > 10 (rank : 357)	NC score	0.099567 (rank : 171)
Query Neighborhood Hits	127	Target Neighborhood Hits	113	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETR_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.055488 (rank : 418)
Query Neighborhood Hits	127	Target Neighborhood Hits	218	Shared Neighborhood Hits	16
SwissProt Accessions	P56730, Q9UP16	Gene names	PRSS12
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Leydin).

NETR_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.056476 (rank : 404)
Query Neighborhood Hits	127	Target Neighborhood Hits	216	Shared Neighborhood Hits	17
SwissProt Accessions	O08762	Gene names	Prss12, Bssp3
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Brain-specific serine protease 3) (BSSP-3).

NID1_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.192315 (rank : 52)
Query Neighborhood Hits	127	Target Neighborhood Hits	329	Shared Neighborhood Hits	33
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_MOUSE
θ value	θ > 10 (rank : 361)	NC score	0.193671 (rank : 51)
Query Neighborhood Hits	127	Target Neighborhood Hits	335	Shared Neighborhood Hits	35
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.183327 (rank : 57)
Query Neighborhood Hits	127	Target Neighborhood Hits	456	Shared Neighborhood Hits	37
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID2_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.183322 (rank : 58)
Query Neighborhood Hits	127	Target Neighborhood Hits	338	Shared Neighborhood Hits	37
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NKG2A_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.088464 (rank : 214)
Query Neighborhood Hits	127	Target Neighborhood Hits	94	Shared Neighborhood Hits	36
SwissProt Accessions	P26715	Gene names	KLRC1, NKG2A
Domain Architecture
Description	NKG2-A/NKG2-B type II integral membrane protein (NKG2-A/B-activating NK receptor) (NK cell receptor A) (CD159a antigen).

NKG2C_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.087631 (rank : 216)
Query Neighborhood Hits	127	Target Neighborhood Hits	100	Shared Neighborhood Hits	37
SwissProt Accessions	P26717, O43802, Q9NR42	Gene names	KLRC2, NKG2C
Domain Architecture
Description	NKG2-C type II integral membrane protein (NKG2-C-activating NK receptor) (NK cell receptor C) (CD159c antigen).

NKG2D_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.129438 (rank : 109)
Query Neighborhood Hits	127	Target Neighborhood Hits	98	Shared Neighborhood Hits	37
SwissProt Accessions	P26718, Q9NR41	Gene names	KLRK1, NKG2D
Domain Architecture
Description	NKG2-D type II integral membrane protein (NKG2-D-activating NK receptor) (NK cell receptor D) (Killer cell lectin-like receptor subfamily K member 1) (CD314 antigen).

NKG2D_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.114860 (rank : 131)
Query Neighborhood Hits	127	Target Neighborhood Hits	102	Shared Neighborhood Hits	36
SwissProt Accessions	O54709	Gene names	Klrk1, Nkg2d
Domain Architecture
Description	NKG2-D type II integral membrane protein (NKG2-D-activating NK receptor) (NK cell receptor D) (Killer cell lectin-like receptor subfamily K member 1) (CD314 antigen).

NKG2E_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.084613 (rank : 227)
Query Neighborhood Hits	127	Target Neighborhood Hits	96	Shared Neighborhood Hits	35
SwissProt Accessions	Q07444, Q96RL0, Q9UP04	Gene names	KLRC3, NKG2E
Domain Architecture
Description	NKG2-E type II integral membrane protein (NKG2-E-activating NK receptor) (NK cell receptor E).

NOTC1_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.076044 (rank : 268)
Query Neighborhood Hits	127	Target Neighborhood Hits	906	Shared Neighborhood Hits	49
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC1_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.081999 (rank : 243)
Query Neighborhood Hits	127	Target Neighborhood Hits	916	Shared Neighborhood Hits	53
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.076252 (rank : 266)
Query Neighborhood Hits	127	Target Neighborhood Hits	1113	Shared Neighborhood Hits	55
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.075955 (rank : 270)
Query Neighborhood Hits	127	Target Neighborhood Hits	1069	Shared Neighborhood Hits	57
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC3_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.070623 (rank : 301)
Query Neighborhood Hits	127	Target Neighborhood Hits	1062	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
θ value	θ > 10 (rank : 374)	NC score	0.069695 (rank : 307)
Query Neighborhood Hits	127	Target Neighborhood Hits	975	Shared Neighborhood Hits	58
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC4_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.073999 (rank : 282)
Query Neighborhood Hits	127	Target Neighborhood Hits	905	Shared Neighborhood Hits	53
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC4_MOUSE
θ value	θ > 10 (rank : 376)	NC score	0.069558 (rank : 308)
Query Neighborhood Hits	127	Target Neighborhood Hits	872	Shared Neighborhood Hits	53
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

NRPN_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.050660 (rank : 463)
Query Neighborhood Hits	127	Target Neighborhood Hits	182	Shared Neighborhood Hits	16
SwissProt Accessions	O60259, Q9HCB3, Q9UIL9, Q9UQ47	Gene names	KLK8, NRPN, PRSS19, TADG14
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8) (Ovasin) (Serine protease TADG-14) (Tumor-associated differentially expressed gene 14 protein).

NTNG2_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.050442 (rank : 465)
Query Neighborhood Hits	127	Target Neighborhood Hits	276	Shared Neighborhood Hits	27
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

OLR1_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.107096 (rank : 149)
Query Neighborhood Hits	127	Target Neighborhood Hits	152	Shared Neighborhood Hits	36
SwissProt Accessions	P78380, Q2PP00, Q7Z484	Gene names	OLR1, LOX1
Domain Architecture	No domain graphic available
Description	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) (hLOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, soluble form].

PCOC1_MOUSE
θ value	θ > 10 (rank : 380)	NC score	0.051834 (rank : 450)
Query Neighborhood Hits	127	Target Neighborhood Hits	100	Shared Neighborhood Hits	16
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC2_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.057433 (rank : 394)
Query Neighborhood Hits	127	Target Neighborhood Hits	73	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC2_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.059318 (rank : 383)
Query Neighborhood Hits	127	Target Neighborhood Hits	73	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCSK5_MOUSE
θ value	θ > 10 (rank : 383)	NC score	0.060047 (rank : 374)
Query Neighborhood Hits	127	Target Neighborhood Hits	613	Shared Neighborhood Hits	45
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

PGCA_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.100605 (rank : 168)
Query Neighborhood Hits	127	Target Neighborhood Hits	821	Shared Neighborhood Hits	54
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PGCA_MOUSE
θ value	θ > 10 (rank : 385)	NC score	0.106261 (rank : 152)
Query Neighborhood Hits	127	Target Neighborhood Hits	643	Shared Neighborhood Hits	45
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

PGCB_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.123714 (rank : 115)
Query Neighborhood Hits	127	Target Neighborhood Hits	478	Shared Neighborhood Hits	49
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

PGCB_MOUSE
θ value	θ > 10 (rank : 387)	NC score	0.123129 (rank : 117)
Query Neighborhood Hits	127	Target Neighborhood Hits	459	Shared Neighborhood Hits	50
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

PHXR5_MOUSE
θ value	θ > 10 (rank : 388)	NC score	0.077652 (rank : 260)
Query Neighborhood Hits	127	Target Neighborhood Hits	102	Shared Neighborhood Hits	21
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

PLMN_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.054092 (rank : 433)
Query Neighborhood Hits	127	Target Neighborhood Hits	204	Shared Neighborhood Hits	16
SwissProt Accessions	P00747, Q15146, Q6PA00	Gene names	PLG
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

PLMN_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.055703 (rank : 415)
Query Neighborhood Hits	127	Target Neighborhood Hits	208	Shared Neighborhood Hits	20
SwissProt Accessions	P20918, Q8CIS2, Q91WJ5	Gene names	Plg
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

POLS2_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.063511 (rank : 344)
Query Neighborhood Hits	127	Target Neighborhood Hits	192	Shared Neighborhood Hits	17
SwissProt Accessions	Q5K4E3, Q8NBY4	Gene names	PRSS36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

POLS2_MOUSE
θ value	θ > 10 (rank : 392)	NC score	0.062159 (rank : 355)
Query Neighborhood Hits	127	Target Neighborhood Hits	188	Shared Neighborhood Hits	16
SwissProt Accessions	Q5K2P8	Gene names	Prss36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

PRG3_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.074026 (rank : 281)
Query Neighborhood Hits	127	Target Neighborhood Hits	74	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2Y8	Gene names	PRG3, MBPH
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein homolog) (Prepro-major basic protein homolog) (Prepro-MBPH).

PRG3_MOUSE
θ value	θ > 10 (rank : 394)	NC score	0.073765 (rank : 284)
Query Neighborhood Hits	127	Target Neighborhood Hits	103	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JL95, Q3SXA9	Gene names	Prg3, Mbp2
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein 2).

PROC_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.086617 (rank : 218)
Query Neighborhood Hits	127	Target Neighborhood Hits	406	Shared Neighborhood Hits	47
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROC_MOUSE
θ value	θ > 10 (rank : 396)	NC score	0.094582 (rank : 189)
Query Neighborhood Hits	127	Target Neighborhood Hits	426	Shared Neighborhood Hits	48
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROS_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.106699 (rank : 150)
Query Neighborhood Hits	127	Target Neighborhood Hits	340	Shared Neighborhood Hits	41
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
θ value	θ > 10 (rank : 398)	NC score	0.101354 (rank : 166)
Query Neighborhood Hits	127	Target Neighborhood Hits	330	Shared Neighborhood Hits	37
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROZ_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.104382 (rank : 160)
Query Neighborhood Hits	127	Target Neighborhood Hits	422	Shared Neighborhood Hits	48
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_MOUSE
θ value	θ > 10 (rank : 400)	NC score	0.093740 (rank : 190)
Query Neighborhood Hits	127	Target Neighborhood Hits	410	Shared Neighborhood Hits	44
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PRS27_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.060556 (rank : 367)
Query Neighborhood Hits	127	Target Neighborhood Hits	177	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BQR3	Gene names	PRSS27, MPN
Domain Architecture
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin) (Channel-activating protease 2) (CAPH2).

PRS27_MOUSE
θ value	θ > 10 (rank : 402)	NC score	0.060554 (rank : 368)
Query Neighborhood Hits	127	Target Neighborhood Hits	175	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BJR6	Gene names	Prss27, Mpn
Domain Architecture	No domain graphic available
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin).

PRSS8_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.059916 (rank : 376)
Query Neighborhood Hits	127	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	Q16651, Q9UCA3	Gene names	PRSS8
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) [Contains: Prostasin light chain; Prostasin heavy chain].

PRSS8_MOUSE
θ value	θ > 10 (rank : 404)	NC score	0.060786 (rank : 363)
Query Neighborhood Hits	127	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ESD1	Gene names	Prss8, Cap1
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) (Channel-activating protease 1) [Contains: Prostasin light chain; Prostasin heavy chain].

RECK_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.055235 (rank : 421)
Query Neighborhood Hits	127	Target Neighborhood Hits	189	Shared Neighborhood Hits	29
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

REG1A_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.122188 (rank : 121)
Query Neighborhood Hits	127	Target Neighborhood Hits	112	Shared Neighborhood Hits	37
SwissProt Accessions	P05451, P11379	Gene names	REG1A, PSPS, REG
Domain Architecture
Description	Lithostathine 1 alpha precursor (Pancreatic stone protein) (PSP) (Pancreatic thread protein) (PTP) (Islet of Langerhans regenerating protein) (REG) (Regenerating protein I alpha) (Islet cells regeneration factor) (ICRF).

REG3A_MOUSE
θ value	θ > 10 (rank : 407)	NC score	0.110653 (rank : 141)
Query Neighborhood Hits	127	Target Neighborhood Hits	80	Shared Neighborhood Hits	34
SwissProt Accessions	O09037	Gene names	Reg3a, Pap2
Domain Architecture
Description	Regenerating islet-derived protein 3 alpha precursor (Reg III-alpha) (Pancreatitis-associated protein 2) (Lithostathine 3) (Islet of Langerhans regenerating protein 3).

REG3B_MOUSE
θ value	θ > 10 (rank : 408)	NC score	0.115851 (rank : 129)
Query Neighborhood Hits	127	Target Neighborhood Hits	87	Shared Neighborhood Hits	36
SwissProt Accessions	P35230	Gene names	Reg3b, Pap, Pap1
Domain Architecture
Description	Regenerating islet-derived protein 3 beta precursor (Reg III-beta) (Pancreatitis-associated protein 1).

REG3G_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.110987 (rank : 140)
Query Neighborhood Hits	127	Target Neighborhood Hits	86	Shared Neighborhood Hits	39
SwissProt Accessions	Q6UW15, Q6FH18	Gene names	REG3G, PAP1B
Domain Architecture	No domain graphic available
Description	Regenerating islet-derived protein 3 gamma precursor (Reg III-gamma) (Pancreatitis-associated protein 1B) (PAP IB).

REG3G_MOUSE
θ value	θ > 10 (rank : 410)	NC score	0.120089 (rank : 123)
Query Neighborhood Hits	127	Target Neighborhood Hits	91	Shared Neighborhood Hits	37
SwissProt Accessions	O09049	Gene names	Reg3g, Pap3
Domain Architecture
Description	Regenerating islet-derived protein 3 gamma precursor (Reg III-gamma) (Pancreatitis-associated protein 3).

REG4_MOUSE
θ value	θ > 10 (rank : 411)	NC score	0.138965 (rank : 97)
Query Neighborhood Hits	127	Target Neighborhood Hits	101	Shared Neighborhood Hits	38
SwissProt Accessions	Q9D8G5, Q3TS25, Q9D858	Gene names	Reg4
Domain Architecture	No domain graphic available
Description	Regenerating islet-derived protein 4 precursor.

SCUB3_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.114447 (rank : 132)
Query Neighborhood Hits	127	Target Neighborhood Hits	428	Shared Neighborhood Hits	52
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
θ value	θ > 10 (rank : 413)	NC score	0.113986 (rank : 135)
Query Neighborhood Hits	127	Target Neighborhood Hits	442	Shared Neighborhood Hits	52
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SFTA1_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.070288 (rank : 303)
Query Neighborhood Hits	127	Target Neighborhood Hits	169	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IWL2, P07714, Q5RIR5, Q5RIR7, Q6PIT0, Q8TC19	Gene names	SFTPA1, PSAP, SFTP1, SFTPA
Domain Architecture	No domain graphic available
Description	Pulmonary surfactant-associated protein A1 precursor (SP-A1) (SP-A) (PSP-A) (PSPA) (Alveolar proteinosis protein) (35 kDa pulmonary surfactant-associated protein).

SFTA2_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.069510 (rank : 309)
Query Neighborhood Hits	127	Target Neighborhood Hits	169	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IWL1, P07714, Q5RIR8, Q5RIR9	Gene names	SFTPA2, PSAP, SFTP1, SFTPA
Domain Architecture	No domain graphic available
Description	Pulmonary surfactant-associated protein A2 precursor (SP-A2) (SP-A) (PSP-A) (PSPA) (Alveolar proteinosis protein) (35 kDa pulmonary surfactant-associated protein).

SFTPA_MOUSE
θ value	θ > 10 (rank : 416)	NC score	0.056225 (rank : 407)
Query Neighborhood Hits	127	Target Neighborhood Hits	169	Shared Neighborhood Hits	26
SwissProt Accessions	P35242	Gene names	Sftpa1, Sftp-1, Sftp1, Sftpa
Domain Architecture
Description	Pulmonary surfactant-associated protein A precursor (SP-A) (PSP-A) (PSAP).

SFTPD_MOUSE
θ value	θ > 10 (rank : 417)	NC score	0.051624 (rank : 453)
Query Neighborhood Hits	127	Target Neighborhood Hits	217	Shared Neighborhood Hits	28
SwissProt Accessions	P50404	Gene names	Sftpd, Sftp4
Domain Architecture
Description	Pulmonary surfactant-associated protein D precursor (SP-D) (PSP-D).

SLIT1_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.059559 (rank : 380)
Query Neighborhood Hits	127	Target Neighborhood Hits	700	Shared Neighborhood Hits	48
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

SLIT1_MOUSE
θ value	θ > 10 (rank : 419)	NC score	0.064383 (rank : 337)
Query Neighborhood Hits	127	Target Neighborhood Hits	715	Shared Neighborhood Hits	53
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

SLIT2_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.058704 (rank : 388)
Query Neighborhood Hits	127	Target Neighborhood Hits	708	Shared Neighborhood Hits	47
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT2_MOUSE
θ value	θ > 10 (rank : 421)	NC score	0.056792 (rank : 400)
Query Neighborhood Hits	127	Target Neighborhood Hits	684	Shared Neighborhood Hits	42
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT3_MOUSE
θ value	θ > 10 (rank : 422)	NC score	0.056012 (rank : 412)
Query Neighborhood Hits	127	Target Neighborhood Hits	700	Shared Neighborhood Hits	40
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

SREC2_HUMAN
θ value	θ > 10 (rank : 423)	NC score	0.072346 (rank : 290)
Query Neighborhood Hits	127	Target Neighborhood Hits	645	Shared Neighborhood Hits	45
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SREC2_MOUSE
θ value	θ > 10 (rank : 424)	NC score	0.067280 (rank : 319)
Query Neighborhood Hits	127	Target Neighborhood Hits	605	Shared Neighborhood Hits	43
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SREC_HUMAN
θ value	θ > 10 (rank : 425)	NC score	0.067000 (rank : 322)
Query Neighborhood Hits	127	Target Neighborhood Hits	645	Shared Neighborhood Hits	52
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

STAB1_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.070206 (rank : 304)
Query Neighborhood Hits	127	Target Neighborhood Hits	546	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB1_MOUSE
θ value	θ > 10 (rank : 427)	NC score	0.070998 (rank : 296)
Query Neighborhood Hits	127	Target Neighborhood Hits	566	Shared Neighborhood Hits	49
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

STAB2_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.075025 (rank : 276)
Query Neighborhood Hits	127	Target Neighborhood Hits	534	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

STAB2_MOUSE
θ value	θ > 10 (rank : 429)	NC score	0.074577 (rank : 278)
Query Neighborhood Hits	127	Target Neighborhood Hits	528	Shared Neighborhood Hits	50
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

SUSD1_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.070735 (rank : 300)
Query Neighborhood Hits	127	Target Neighborhood Hits	285	Shared Neighborhood Hits	29
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TECTA_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.051000 (rank : 462)
Query Neighborhood Hits	127	Target Neighborhood Hits	239	Shared Neighborhood Hits	29
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

TECTA_MOUSE
θ value	θ > 10 (rank : 432)	NC score	0.053768 (rank : 434)
Query Neighborhood Hits	127	Target Neighborhood Hits	244	Shared Neighborhood Hits	33
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TENA_HUMAN
θ value	θ > 10 (rank : 433)	NC score	0.093019 (rank : 194)
Query Neighborhood Hits	127	Target Neighborhood Hits	631	Shared Neighborhood Hits	49
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENA_MOUSE
θ value	θ > 10 (rank : 434)	NC score	0.091819 (rank : 200)
Query Neighborhood Hits	127	Target Neighborhood Hits	596	Shared Neighborhood Hits	54
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TENR_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.055287 (rank : 420)
Query Neighborhood Hits	127	Target Neighborhood Hits	526	Shared Neighborhood Hits	48
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TENR_MOUSE
θ value	θ > 10 (rank : 436)	NC score	0.057185 (rank : 395)
Query Neighborhood Hits	127	Target Neighborhood Hits	531	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

TENX_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.071392 (rank : 295)
Query Neighborhood Hits	127	Target Neighborhood Hits	789	Shared Neighborhood Hits	50
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TEST_HUMAN
θ value	θ > 10 (rank : 438)	NC score	0.062956 (rank : 350)
Query Neighborhood Hits	127	Target Neighborhood Hits	172	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y6M0, Q9NS34, Q9P2V6	Gene names	PRSS21, ESP1, TEST1
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Eosinophil serine protease 1) (ESP- 1).

TEST_MOUSE
θ value	θ > 10 (rank : 439)	NC score	0.060494 (rank : 369)
Query Neighborhood Hits	127	Target Neighborhood Hits	174	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JHJ7, Q9DA14	Gene names	Prss21
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Tryptase 4).

TETN_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.103538 (rank : 161)
Query Neighborhood Hits	127	Target Neighborhood Hits	90	Shared Neighborhood Hits	35
SwissProt Accessions	P05452	Gene names	CLEC3B, TNA
Domain Architecture
Description	Tetranectin precursor (TN) (C-type lectin domain family 3 member B) (Plasminogen kringle 4-binding protein).

TETN_MOUSE
θ value	θ > 10 (rank : 441)	NC score	0.092949 (rank : 195)
Query Neighborhood Hits	127	Target Neighborhood Hits	77	Shared Neighborhood Hits	29
SwissProt Accessions	P43025	Gene names	Clec3b, Tna
Domain Architecture
Description	Tetranectin precursor (TN) (C-type lectin domain family 3 member B) (Plasminogen kringle 4-binding protein).

THRB_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.055096 (rank : 422)
Query Neighborhood Hits	127	Target Neighborhood Hits	196	Shared Neighborhood Hits	16
SwissProt Accessions	P00734	Gene names	F2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

THRB_MOUSE
θ value	θ > 10 (rank : 443)	NC score	0.053641 (rank : 436)
Query Neighborhood Hits	127	Target Neighborhood Hits	195	Shared Neighborhood Hits	16
SwissProt Accessions	P19221	Gene names	F2, Cf2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

TLL1_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.095434 (rank : 184)
Query Neighborhood Hits	127	Target Neighborhood Hits	236	Shared Neighborhood Hits	39
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL1_MOUSE
θ value	θ > 10 (rank : 445)	NC score	0.095684 (rank : 183)
Query Neighborhood Hits	127	Target Neighborhood Hits	237	Shared Neighborhood Hits	39
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL2_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.092277 (rank : 197)
Query Neighborhood Hits	127	Target Neighborhood Hits	241	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL2_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.091990 (rank : 199)
Query Neighborhood Hits	127	Target Neighborhood Hits	240	Shared Neighborhood Hits	40
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TM11D_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.062025 (rank : 356)
Query Neighborhood Hits	127	Target Neighborhood Hits	176	Shared Neighborhood Hits	16
SwissProt Accessions	O60235	Gene names	TMPRSS11D, HAT
Domain Architecture
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

TM11D_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.063364 (rank : 346)
Query Neighborhood Hits	127	Target Neighborhood Hits	179	Shared Neighborhood Hits	16
SwissProt Accessions	Q8VHK8, Q7TNX3, Q8VDV1	Gene names	Tmprss11d, Mat
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) (AT) (Adrenal secretory serine protease) (AsP) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

TM11E_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.065560 (rank : 327)
Query Neighborhood Hits	127	Target Neighborhood Hits	181	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UL52, Q6UW31	Gene names	TMPRSS11E, DESC1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

TM11E_MOUSE
θ value	θ > 10 (rank : 451)	NC score	0.063975 (rank : 341)
Query Neighborhood Hits	127	Target Neighborhood Hits	176	Shared Neighborhood Hits	16
SwissProt Accessions	Q5S248, Q8BM10	Gene names	Tmprss11e, Desc1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

TMPS2_HUMAN
θ value	θ > 10 (rank : 452)	NC score	0.089071 (rank : 209)
Query Neighborhood Hits	127	Target Neighborhood Hits	252	Shared Neighborhood Hits	48
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS2_MOUSE
θ value	θ > 10 (rank : 453)	NC score	0.100358 (rank : 169)
Query Neighborhood Hits	127	Target Neighborhood Hits	243	Shared Neighborhood Hits	56
SwissProt Accessions	Q9JIQ8, Q9JKC4, Q9QY82	Gene names	Tmprss2
Domain Architecture
Description	Transmembrane protease, serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS4_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.076849 (rank : 264)
Query Neighborhood Hits	127	Target Neighborhood Hits	203	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NRS4, Q5XKQ6, Q6UX37, Q9NZA5	Gene names	TMPRSS4, TMPRSS3
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Membrane-type serine protease 2) (MT-SP2).

TMPS4_MOUSE
θ value	θ > 10 (rank : 455)	NC score	0.073720 (rank : 285)
Query Neighborhood Hits	127	Target Neighborhood Hits	210	Shared Neighborhood Hits	35
SwissProt Accessions	Q8VCA5	Gene names	Tmprss4, Cap2
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (mCAP2).

TMPS5_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.063310 (rank : 347)
Query Neighborhood Hits	127	Target Neighborhood Hits	181	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H3S3	Gene names	TMPRSS5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

TMPS5_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.063052 (rank : 349)
Query Neighborhood Hits	127	Target Neighborhood Hits	185	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ER04, Q9ER02, Q9ER03	Gene names	Tmprss5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

TMPSD_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.070933 (rank : 298)
Query Neighborhood Hits	127	Target Neighborhood Hits	333	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TMPSD_MOUSE
θ value	θ > 10 (rank : 459)	NC score	0.067426 (rank : 318)
Query Neighborhood Hits	127	Target Neighborhood Hits	334	Shared Neighborhood Hits	25
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TMSP8_MOUSE
θ value	θ > 10 (rank : 460)	NC score	0.059633 (rank : 379)
Query Neighborhood Hits	127	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QYZ9, Q91XC4	Gene names	Tmprss8, Disp
Domain Architecture
Description	Transmembrane serine protease 8 precursor (EC 3.4.21.-) (Distal intestinal serine protease).

TPA_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.065766 (rank : 326)
Query Neighborhood Hits	127	Target Neighborhood Hits	324	Shared Neighborhood Hits	34
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TPA_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.064832 (rank : 333)
Query Neighborhood Hits	127	Target Neighborhood Hits	335	Shared Neighborhood Hits	35
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TRY1_HUMAN
θ value	θ > 10 (rank : 463)	NC score	0.052494 (rank : 444)
Query Neighborhood Hits	127	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P07477, Q92955, Q9HAN4, Q9HAN5, Q9HAN6, Q9HAN7	Gene names	PRSS1, TRP1, TRY1, TRYP1
Domain Architecture
Description	Trypsin-1 precursor (EC 3.4.21.4) (Trypsin I) (Cationic trypsinogen).

TRY2_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.052435 (rank : 445)
Query Neighborhood Hits	127	Target Neighborhood Hits	175	Shared Neighborhood Hits	16
SwissProt Accessions	P07478	Gene names	PRSS2, TRY2, TRYP2
Domain Architecture
Description	Trypsin-2 precursor (EC 3.4.21.4) (Trypsin II) (Anionic trypsinogen).

TRY2_MOUSE
θ value	θ > 10 (rank : 465)	NC score	0.052874 (rank : 439)
Query Neighborhood Hits	127	Target Neighborhood Hits	174	Shared Neighborhood Hits	16
SwissProt Accessions	P07146	Gene names	Prss2, Try2
Domain Architecture
Description	Anionic trypsin-2 precursor (EC 3.4.21.4) (Anionic trypsin II) (Pretrypsinogen II).

TRY3_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.052181 (rank : 448)
Query Neighborhood Hits	127	Target Neighborhood Hits	178	Shared Neighborhood Hits	16
SwissProt Accessions	P35030, P15951, Q15665, Q9UQV3	Gene names	PRSS3, PRSS4, TRY3, TRY4
Domain Architecture
Description	Trypsin-3 precursor (EC 3.4.21.4) (Trypsin III) (Brain trypsinogen) (Mesotrypsinogen) (Trypsin IV).

TRYA1_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.056723 (rank : 402)
Query Neighborhood Hits	127	Target Neighborhood Hits	177	Shared Neighborhood Hits	16
SwissProt Accessions	P15157, Q9H2Y5, Q9UQI1	Gene names	TPSAB1, TPS1
Domain Architecture
Description	Tryptase alpha-1 precursor (EC 3.4.21.59) (Tryptase-1).

TRYB1_HUMAN
θ value	θ > 10 (rank : 468)	NC score	0.056973 (rank : 398)
Query Neighborhood Hits	127	Target Neighborhood Hits	175	Shared Neighborhood Hits	16
SwissProt Accessions	Q15661, Q15663, Q9H2Y4	Gene names	TPSAB1, TPSB1
Domain Architecture
Description	Tryptase beta-1 precursor (EC 3.4.21.59) (Tryptase-1) (Tryptase I).

TRYB1_MOUSE
θ value	θ > 10 (rank : 469)	NC score	0.057095 (rank : 397)
Query Neighborhood Hits	127	Target Neighborhood Hits	175	Shared Neighborhood Hits	16
SwissProt Accessions	Q02844	Gene names	Tpsab1, Mcpt7
Domain Architecture
Description	Tryptase precursor (EC 3.4.21.59) (Mast cell protease 7) (MMCP-7) (Tryptase alpha/beta-1).

TRYB2_HUMAN
θ value	θ > 10 (rank : 470)	NC score	0.056973 (rank : 399)
Query Neighborhood Hits	127	Target Neighborhood Hits	175	Shared Neighborhood Hits	16
SwissProt Accessions	P20231, O95827, Q15664, Q9UQI6, Q9UQI7	Gene names	TPSB2, TPS2
Domain Architecture
Description	Tryptase beta-2 precursor (EC 3.4.21.59) (Tryptase-2) (Tryptase II).

TRYD_HUMAN
θ value	θ > 10 (rank : 471)	NC score	0.056129 (rank : 410)
Query Neighborhood Hits	127	Target Neighborhood Hits	175	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BZJ3, O95824, Q8TDI6, Q96L36, Q96RZ5, Q9H2Y6, Q9UQI8	Gene names	TPSD1
Domain Architecture
Description	Tryptase delta precursor (EC 3.4.21.59) (Delta tryptase) (Mast cell mMCP-7-like) (Tryptase-3) (HmMCP-3-like tryptase III).

TRYG1_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.059379 (rank : 382)
Query Neighborhood Hits	127	Target Neighborhood Hits	179	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NRR2, Q96RZ8, Q9C015, Q9NRQ8, Q9UBB2	Gene names	TPSG1, TMT
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

TRYG1_MOUSE
θ value	θ > 10 (rank : 473)	NC score	0.059556 (rank : 381)
Query Neighborhood Hits	127	Target Neighborhood Hits	181	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QUL7	Gene names	Tpsg1, Tmt
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

TSG6_HUMAN
θ value	θ > 10 (rank : 474)	NC score	0.071801 (rank : 292)
Query Neighborhood Hits	127	Target Neighborhood Hits	91	Shared Neighborhood Hits	15
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
θ value	θ > 10 (rank : 475)	NC score	0.072760 (rank : 288)
Query Neighborhood Hits	127	Target Neighborhood Hits	91	Shared Neighborhood Hits	15
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

TSP1_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.059186 (rank : 387)
Query Neighborhood Hits	127	Target Neighborhood Hits	389	Shared Neighborhood Hits	47
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_MOUSE
θ value	θ > 10 (rank : 477)	NC score	0.056775 (rank : 401)
Query Neighborhood Hits	127	Target Neighborhood Hits	396	Shared Neighborhood Hits	47
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP50_HUMAN
θ value	θ > 10 (rank : 478)	NC score	0.059972 (rank : 375)
Query Neighborhood Hits	127	Target Neighborhood Hits	178	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UI38	Gene names	TSP50
Domain Architecture
Description	Testis-specific protease-like protein 50 precursor.

UROK_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.060357 (rank : 371)
Query Neighborhood Hits	127	Target Neighborhood Hits	272	Shared Neighborhood Hits	28
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

UROK_MOUSE
θ value	θ > 10 (rank : 480)	NC score	0.059304 (rank : 384)
Query Neighborhood Hits	127	Target Neighborhood Hits	273	Shared Neighborhood Hits	28
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

UROM_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.064988 (rank : 332)
Query Neighborhood Hits	127	Target Neighborhood Hits	284	Shared Neighborhood Hits	32
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_MOUSE
θ value	θ > 10 (rank : 482)	NC score	0.063826 (rank : 343)
Query Neighborhood Hits	127	Target Neighborhood Hits	276	Shared Neighborhood Hits	32
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

WIF1_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.066400 (rank : 325)
Query Neighborhood Hits	127	Target Neighborhood Hits	392	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_MOUSE
θ value	θ > 10 (rank : 484)	NC score	0.063424 (rank : 345)
Query Neighborhood Hits	127	Target Neighborhood Hits	393	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

ZAN_MOUSE
θ value	θ > 10 (rank : 485)	NC score	0.108322 (rank : 145)
Query Neighborhood Hits	127	Target Neighborhood Hits	808	Shared Neighborhood Hits	57
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

Hits sorted by NC score

IDD_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	127	Target Neighborhood Hits	127	Shared Neighborhood Hits	127
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

IDD_MOUSE
NC score	0.983115 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	127	Target Neighborhood Hits	151	Shared Neighborhood Hits	106
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

CD320_HUMAN
NC score	0.544291 (rank : 3)	θ value	0.000461057 (rank : 26)
Query Neighborhood Hits	127	Target Neighborhood Hits	103	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

LRP5_HUMAN
NC score	0.505857 (rank : 4)	θ value	1.47974e-10 (rank : 3)
Query Neighborhood Hits	127	Target Neighborhood Hits	224	Shared Neighborhood Hits	63
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LRP5_MOUSE
NC score	0.505701 (rank : 5)	θ value	1.47974e-10 (rank : 4)
Query Neighborhood Hits	127	Target Neighborhood Hits	236	Shared Neighborhood Hits	64
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

LRP6_MOUSE
NC score	0.496435 (rank : 6)	θ value	9.59137e-10 (rank : 6)
Query Neighborhood Hits	127	Target Neighborhood Hits	232	Shared Neighborhood Hits	65
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_HUMAN
NC score	0.495637 (rank : 7)	θ value	9.59137e-10 (rank : 5)
Query Neighborhood Hits	127	Target Neighborhood Hits	235	Shared Neighborhood Hits	65
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP10_HUMAN
NC score	0.443328 (rank : 8)	θ value	0.00509761 (rank : 39)
Query Neighborhood Hits	127	Target Neighborhood Hits	197	Shared Neighborhood Hits	63
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP10_MOUSE
NC score	0.440315 (rank : 9)	θ value	0.00665767 (rank : 40)
Query Neighborhood Hits	127	Target Neighborhood Hits	169	Shared Neighborhood Hits	60
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LDLR_MOUSE
NC score	0.429681 (rank : 10)	θ value	8.11959e-09 (rank : 7)
Query Neighborhood Hits	127	Target Neighborhood Hits	382	Shared Neighborhood Hits	71
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP4_HUMAN
NC score	0.428356 (rank : 11)	θ value	3.19293e-05 (rank : 16)
Query Neighborhood Hits	127	Target Neighborhood Hits	355	Shared Neighborhood Hits	70
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP8_HUMAN
NC score	0.427626 (rank : 12)	θ value	2.88788e-06 (rank : 10)
Query Neighborhood Hits	127	Target Neighborhood Hits	346	Shared Neighborhood Hits	69
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP4_MOUSE
NC score	0.424691 (rank : 13)	θ value	3.19293e-05 (rank : 17)
Query Neighborhood Hits	127	Target Neighborhood Hits	351	Shared Neighborhood Hits	69
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LRP3_HUMAN
NC score	0.421983 (rank : 14)	θ value	0.000461057 (rank : 27)
Query Neighborhood Hits	127	Target Neighborhood Hits	280	Shared Neighborhood Hits	64
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

LRP8_MOUSE
NC score	0.416932 (rank : 15)	θ value	3.19293e-05 (rank : 18)
Query Neighborhood Hits	127	Target Neighborhood Hits	385	Shared Neighborhood Hits	69
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

VLDLR_HUMAN
NC score	0.415233 (rank : 16)	θ value	2.44474e-05 (rank : 14)
Query Neighborhood Hits	127	Target Neighborhood Hits	383	Shared Neighborhood Hits	70
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

LDLR_HUMAN
NC score	0.414737 (rank : 17)	θ value	4.92598e-06 (rank : 11)
Query Neighborhood Hits	127	Target Neighborhood Hits	375	Shared Neighborhood Hits	69
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

VLDLR_MOUSE
NC score	0.414022 (rank : 18)	θ value	9.29e-05 (rank : 22)
Query Neighborhood Hits	127	Target Neighborhood Hits	360	Shared Neighborhood Hits	70
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

LRP2_HUMAN
NC score	0.409468 (rank : 19)	θ value	4.1701e-05 (rank : 19)
Query Neighborhood Hits	127	Target Neighborhood Hits	573	Shared Neighborhood Hits	78
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

SORL_HUMAN
NC score	0.384754 (rank : 20)	θ value	0.000461057 (rank : 28)
Query Neighborhood Hits	127	Target Neighborhood Hits	440	Shared Neighborhood Hits	69
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SORL_MOUSE
NC score	0.384749 (rank : 21)	θ value	0.000461057 (rank : 29)
Query Neighborhood Hits	127	Target Neighborhood Hits	439	Shared Neighborhood Hits	69
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

LRP1B_MOUSE
NC score	0.384734 (rank : 22)	θ value	0.00035302 (rank : 25)
Query Neighborhood Hits	127	Target Neighborhood Hits	606	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1_HUMAN
NC score	0.384636 (rank : 23)	θ value	3.19293e-05 (rank : 15)
Query Neighborhood Hits	127	Target Neighborhood Hits	617	Shared Neighborhood Hits	77
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP1B_HUMAN
NC score	0.384227 (rank : 24)	θ value	0.00035302 (rank : 24)
Query Neighborhood Hits	127	Target Neighborhood Hits	602	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP12_HUMAN
NC score	0.380416 (rank : 25)	θ value	0.00175202 (rank : 33)
Query Neighborhood Hits	127	Target Neighborhood Hits	205	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
NC score	0.380296 (rank : 26)	θ value	0.00175202 (rank : 34)
Query Neighborhood Hits	127	Target Neighborhood Hits	180	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

SSPO_MOUSE
NC score	0.284937 (rank : 27)	θ value	0.00298849 (rank : 37)
Query Neighborhood Hits	127	Target Neighborhood Hits	800	Shared Neighborhood Hits	81
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

SPIT1_HUMAN
NC score	0.279287 (rank : 28)	θ value	0.0431538 (rank : 53)
Query Neighborhood Hits	127	Target Neighborhood Hits	100	Shared Neighborhood Hits	54
SwissProt Accessions	O43278, Q7Z7D2	Gene names	SPINT1, HAI1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

LY75_MOUSE
NC score	0.270031 (rank : 29)	θ value	1.99992e-07 (rank : 9)
Query Neighborhood Hits	127	Target Neighborhood Hits	155	Shared Neighborhood Hits	43
SwissProt Accessions	Q60767, Q8C7T3, Q91XL8, Q9QUZ6	Gene names	Ly75, Cd205
Domain Architecture
Description	Lymphocyte antigen 75 precursor (DEC-205) (CD205 antigen).

LY75_HUMAN
NC score	0.263995 (rank : 30)	θ value	1.17247e-07 (rank : 8)
Query Neighborhood Hits	127	Target Neighborhood Hits	169	Shared Neighborhood Hits	41
SwissProt Accessions	O60449, O75913, Q7Z575, Q7Z577	Gene names	LY75, CD205
Domain Architecture
Description	Lymphocyte antigen 75 precursor (DEC-205) (gp200-MR6) (CD205 antigen).

LRP11_MOUSE
NC score	0.249929 (rank : 31)	θ value	3.0926 (rank : 101)
Query Neighborhood Hits	127	Target Neighborhood Hits	81	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CB67, Q8C7Y7	Gene names	Lrp11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

ST14_HUMAN
NC score	0.247152 (rank : 32)	θ value	6.43352e-06 (rank : 12)
Query Neighborhood Hits	127	Target Neighborhood Hits	409	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

CO9_HUMAN
NC score	0.247139 (rank : 33)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	127	Target Neighborhood Hits	147	Shared Neighborhood Hits	59
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

CORIN_HUMAN
NC score	0.245415 (rank : 34)	θ value	2.44474e-05 (rank : 13)
Query Neighborhood Hits	127	Target Neighborhood Hits	453	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

CORIN_MOUSE
NC score	0.244198 (rank : 35)	θ value	0.000158464 (rank : 23)
Query Neighborhood Hits	127	Target Neighborhood Hits	451	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

LRP11_HUMAN
NC score	0.240256 (rank : 36)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	127	Target Neighborhood Hits	82	Shared Neighborhood Hits	53
SwissProt Accessions	Q86VZ4, Q5VYC0, Q96SN6	Gene names	LRP11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

ST14_MOUSE
NC score	0.239623 (rank : 37)	θ value	0.00102713 (rank : 31)
Query Neighborhood Hits	127	Target Neighborhood Hits	419	Shared Neighborhood Hits	66
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

EGF_HUMAN
NC score	0.232775 (rank : 38)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	127	Target Neighborhood Hits	343	Shared Neighborhood Hits	40
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EGF_MOUSE
NC score	0.225850 (rank : 39)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	127	Target Neighborhood Hits	358	Shared Neighborhood Hits	40
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

MFRP_HUMAN
NC score	0.220249 (rank : 40)	θ value	0.0252991 (rank : 44)
Query Neighborhood Hits	127	Target Neighborhood Hits	165	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

SPIT1_MOUSE
NC score	0.219776 (rank : 41)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	127	Target Neighborhood Hits	96	Shared Neighborhood Hits	57
SwissProt Accessions	Q9R097	Gene names	Spint1, Hai1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

CO9_MOUSE
NC score	0.219311 (rank : 42)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	127	Target Neighborhood Hits	153	Shared Neighborhood Hits	59
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

MRC1_HUMAN
NC score	0.218999 (rank : 43)	θ value	0.00175202 (rank : 35)
Query Neighborhood Hits	127	Target Neighborhood Hits	157	Shared Neighborhood Hits	44
SwissProt Accessions	P22897	Gene names	MRC1
Domain Architecture
Description	Macrophage mannose receptor 1 precursor (MMR) (CD206 antigen).

PGBM_MOUSE
NC score	0.213499 (rank : 44)	θ value	9.29e-05 (rank : 21)
Query Neighborhood Hits	127	Target Neighborhood Hits	1073	Shared Neighborhood Hits	77
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

MRC2_MOUSE
NC score	0.211827 (rank : 45)	θ value	0.0252991 (rank : 46)
Query Neighborhood Hits	127	Target Neighborhood Hits	159	Shared Neighborhood Hits	43
SwissProt Accessions	Q64449, Q6ZQ64, Q8C6P0	Gene names	Mrc2, Kiaa0709
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 2 precursor (Lectin lambda) (CD280 antigen).

MRC1_MOUSE
NC score	0.207987 (rank : 46)	θ value	0.0252991 (rank : 45)
Query Neighborhood Hits	127	Target Neighborhood Hits	156	Shared Neighborhood Hits	43
SwissProt Accessions	Q61830, Q8C502	Gene names	Mrc1
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 1 precursor (MMR) (CD206 antigen).

MRC2_HUMAN
NC score	0.205459 (rank : 47)	θ value	0.0961366 (rank : 59)
Query Neighborhood Hits	127	Target Neighborhood Hits	162	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UBG0, Q7LGE7, Q9Y5P9	Gene names	MRC2, ENDO180, KIAA0709, UPARAP
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 2 precursor (Urokinase receptor-associated protein) (Endocytic receptor 180) (CD280 antigen).

TMPS7_MOUSE
NC score	0.205404 (rank : 48)	θ value	0.0113563 (rank : 42)
Query Neighborhood Hits	127	Target Neighborhood Hits	275	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

PGBM_HUMAN
NC score	0.204066 (rank : 49)	θ value	7.1131e-05 (rank : 20)
Query Neighborhood Hits	127	Target Neighborhood Hits	1113	Shared Neighborhood Hits	75
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

TMPS7_HUMAN
NC score	0.203666 (rank : 50)	θ value	0.0252991 (rank : 47)
Query Neighborhood Hits	127	Target Neighborhood Hits	275	Shared Neighborhood Hits	58
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

NID1_MOUSE
NC score	0.193671 (rank : 51)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	127	Target Neighborhood Hits	335	Shared Neighborhood Hits	35
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_HUMAN
NC score	0.192315 (rank : 52)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	127	Target Neighborhood Hits	329	Shared Neighborhood Hits	33
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

CO6_HUMAN
NC score	0.187980 (rank : 53)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	127	Target Neighborhood Hits	331	Shared Neighborhood Hits	66
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

MFRP_MOUSE
NC score	0.186784 (rank : 54)	θ value	1.81305 (rank : 92)
Query Neighborhood Hits	127	Target Neighborhood Hits	166	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

CO8B_MOUSE
NC score	0.186580 (rank : 55)	θ value	0.21417 (rank : 64)
Query Neighborhood Hits	127	Target Neighborhood Hits	224	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO8B_HUMAN
NC score	0.185776 (rank : 56)	θ value	0.365318 (rank : 72)
Query Neighborhood Hits	127	Target Neighborhood Hits	199	Shared Neighborhood Hits	57
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

NID2_HUMAN
NC score	0.183327 (rank : 57)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	127	Target Neighborhood Hits	456	Shared Neighborhood Hits	37
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID2_MOUSE
NC score	0.183322 (rank : 58)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	127	Target Neighborhood Hits	338	Shared Neighborhood Hits	37
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

CO8A_MOUSE
NC score	0.183188 (rank : 59)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	127	Target Neighborhood Hits	182	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

TMPS6_HUMAN
NC score	0.178853 (rank : 60)	θ value	2.36792 (rank : 97)
Query Neighborhood Hits	127	Target Neighborhood Hits	338	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

CFAI_HUMAN
NC score	0.174363 (rank : 61)	θ value	0.813845 (rank : 80)
Query Neighborhood Hits	127	Target Neighborhood Hits	289	Shared Neighborhood Hits	57
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CO8A_HUMAN
NC score	0.168508 (rank : 62)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	127	Target Neighborhood Hits	200	Shared Neighborhood Hits	58
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

TMPS6_MOUSE
NC score	0.167643 (rank : 63)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	127	Target Neighborhood Hits	341	Shared Neighborhood Hits	58
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

CLC10_HUMAN
NC score	0.164002 (rank : 64)	θ value	0.0736092 (rank : 54)
Query Neighborhood Hits	127	Target Neighborhood Hits	134	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IUN9, Q14538, Q6PIW3	Gene names	CLEC10A, CLECSF14, HML
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 10 member A (C-type lectin superfamily member 14) (Macrophage lectin 2) (CD301 antigen).

CR001_HUMAN
NC score	0.162637 (rank : 65)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	127	Target Neighborhood Hits	68	Shared Neighborhood Hits	45
SwissProt Accessions	O15165, O15166, O15167, O15168, Q6NXP3	Gene names	C18orf1
Domain Architecture
Description	Protein C18orf1.

CFAI_MOUSE
NC score	0.162253 (rank : 66)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	127	Target Neighborhood Hits	290	Shared Neighborhood Hits	57
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

C209A_MOUSE
NC score	0.161389 (rank : 67)	θ value	0.279714 (rank : 68)
Query Neighborhood Hits	127	Target Neighborhood Hits	117	Shared Neighborhood Hits	39
SwissProt Accessions	Q91ZX1, Q3TAT9, Q91ZW5	Gene names	Cd209a, Cire
Domain Architecture
Description	CD209 antigen-like protein A (Dendritic cell-specific ICAM-3-grabbing nonintegrin) (DC-SIGN).

ENTK_MOUSE
NC score	0.160462 (rank : 68)	θ value	0.00228821 (rank : 36)
Query Neighborhood Hits	127	Target Neighborhood Hits	338	Shared Neighborhood Hits	62
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

CSPG3_HUMAN
NC score	0.160337 (rank : 69)	θ value	0.000786445 (rank : 30)
Query Neighborhood Hits	127	Target Neighborhood Hits	676	Shared Neighborhood Hits	57
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CR001_MOUSE
NC score	0.160027 (rank : 70)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	127	Target Neighborhood Hits	67	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BWJ4	Gene names	D18Ertd653e
Domain Architecture	No domain graphic available
Description	Protein C18orf1 homolog.

ENTK_HUMAN
NC score	0.157867 (rank : 71)	θ value	0.00175202 (rank : 32)
Query Neighborhood Hits	127	Target Neighborhood Hits	310	Shared Neighborhood Hits	60
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

CLC4M_HUMAN
NC score	0.157340 (rank : 72)	θ value	0.0193708 (rank : 43)
Query Neighborhood Hits	127	Target Neighborhood Hits	291	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H2X3, Q69F40, Q969M4, Q96QP3, Q96QP4, Q96QP5, Q96QP6, Q9BXS3, Q9H2Q9, Q9H8F0, Q9Y2A8	Gene names	CLEC4M, CD209L, CD209L1
Domain Architecture
Description	C-type lectin domain family 4 member M (CD209 antigen-like protein 1) (Dendritic cell-specific ICAM-3-grabbing nonintegrin 2) (DC-SIGN2) (DC-SIGN-related protein) (DC-SIGNR) (Liver/lymph node-specific ICAM- 3-grabbing nonintegrin) (L-SIGN) (CD299 antigen).

CLC6A_HUMAN
NC score	0.157266 (rank : 73)	θ value	0.62314 (rank : 76)
Query Neighborhood Hits	127	Target Neighborhood Hits	119	Shared Neighborhood Hits	41
SwissProt Accessions	Q6EIG7	Gene names	CLEC6A, CLECSF10, DECTIN2
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 6 member A (C-type lectin superfamily member 10) (Dendritic cell-associated lectin 2) (DC-associated C-type lectin-2) (DECTIN-2).

CD248_HUMAN
NC score	0.155837 (rank : 74)	θ value	0.365318 (rank : 71)
Query Neighborhood Hits	127	Target Neighborhood Hits	679	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

GLU2B_HUMAN
NC score	0.155801 (rank : 75)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	127	Target Neighborhood Hits	377	Shared Neighborhood Hits	43
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

CLC4E_MOUSE
NC score	0.155398 (rank : 76)	θ value	0.47712 (rank : 74)
Query Neighborhood Hits	127	Target Neighborhood Hits	113	Shared Neighborhood Hits	39
SwissProt Accessions	Q9R0Q8	Gene names	Clec4e, Clecsf9, Mincle
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member E (C-type lectin superfamily member 9) (Macrophage-inducible C-type lectin).

REG1B_HUMAN
NC score	0.155234 (rank : 77)	θ value	0.125558 (rank : 62)
Query Neighborhood Hits	127	Target Neighborhood Hits	120	Shared Neighborhood Hits	39
SwissProt Accessions	P48304	Gene names	REG1B, REGL
Domain Architecture
Description	Lithostathine 1 beta precursor (Regenerating protein I beta).

CLC6A_MOUSE
NC score	0.155063 (rank : 78)	θ value	0.62314 (rank : 77)
Query Neighborhood Hits	127	Target Neighborhood Hits	111	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JKF4, Q9JKF2, Q9JKF3	Gene names	Clec6a, Clecsf10, Dectin2
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 6 member A (C-type lectin superfamily member 10) (Dendritic cell-associated lectin 2) (DC-associated C-type lectin-2) (DECTIN-2).

CLC4A_HUMAN
NC score	0.154672 (rank : 79)	θ value	1.38821 (rank : 84)
Query Neighborhood Hits	127	Target Neighborhood Hits	114	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UMR7, Q8WXW9, Q9H2Z9, Q9NS33, Q9UI34	Gene names	CLEC4A, CLECSF6, DCIR, LLIR
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member A (C-type lectin superfamily member 6) (Dendritic cell immunoreceptor) (Lectin-like immunoreceptor) (C-type lectin DDB27).

ASGR2_HUMAN
NC score	0.153108 (rank : 80)	θ value	0.365318 (rank : 69)
Query Neighborhood Hits	127	Target Neighborhood Hits	121	Shared Neighborhood Hits	38
SwissProt Accessions	P07307, O00448, Q03969	Gene names	ASGR2
Domain Architecture
Description	Asialoglycoprotein receptor 2 (ASGP-R 2) (ASGPR 2) (Hepatic lectin H2).

CSPG3_MOUSE
NC score	0.152737 (rank : 81)	θ value	0.00509761 (rank : 38)
Query Neighborhood Hits	127	Target Neighborhood Hits	657	Shared Neighborhood Hits	56
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CD72_HUMAN
NC score	0.151020 (rank : 82)	θ value	0.0330416 (rank : 50)
Query Neighborhood Hits	127	Target Neighborhood Hits	345	Shared Neighborhood Hits	35
SwissProt Accessions	P21854	Gene names	CD72
Domain Architecture
Description	B-cell differentiation antigen CD72 (Lyb-2).

C209D_MOUSE
NC score	0.150769 (rank : 83)	θ value	0.813845 (rank : 79)
Query Neighborhood Hits	127	Target Neighborhood Hits	120	Shared Neighborhood Hits	40
SwissProt Accessions	Q91ZW8, Q8VIK4	Gene names	Cd209d
Domain Architecture
Description	CD209 antigen-like protein D (DC-SIGN-related protein 3) (DC-SIGNR3).

C209C_MOUSE
NC score	0.149451 (rank : 84)	θ value	0.365318 (rank : 70)
Query Neighborhood Hits	127	Target Neighborhood Hits	114	Shared Neighborhood Hits	37
SwissProt Accessions	Q91ZW9	Gene names	Cd209c
Domain Architecture
Description	CD209 antigen-like protein C (DC-SIGN-related protein 2) (DC-SIGNR2).

CLC1A_MOUSE
NC score	0.148041 (rank : 85)	θ value	0.21417 (rank : 63)
Query Neighborhood Hits	127	Target Neighborhood Hits	100	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BWY2, Q7TPX7, Q8BMH5	Gene names	Clec1a
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 1 member A.

CD248_MOUSE
NC score	0.147470 (rank : 86)	θ value	1.81305 (rank : 89)
Query Neighborhood Hits	127	Target Neighborhood Hits	578	Shared Neighborhood Hits	42
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

ASGR2_MOUSE
NC score	0.147357 (rank : 87)	θ value	1.38821 (rank : 82)
Query Neighborhood Hits	127	Target Neighborhood Hits	123	Shared Neighborhood Hits	40
SwissProt Accessions	P24721	Gene names	Asgr2, Asgr-2
Domain Architecture
Description	Asialoglycoprotein receptor 2 (ASGP-R 2) (ASGPR 2) (Hepatic lectin 2) (MHL-2).

C209B_MOUSE
NC score	0.146935 (rank : 88)	θ value	1.81305 (rank : 88)
Query Neighborhood Hits	127	Target Neighborhood Hits	140	Shared Neighborhood Hits	39
SwissProt Accessions	Q8CJ91, Q8BGZ0, Q8BHK7, Q8CJ86, Q8CJ87, Q8CJ88, Q8CJ89, Q8CJ90, Q8CJ92, Q8CJ93, Q8CJ94, Q91ZW4, Q91ZX0, Q9D8V4	Gene names	Cd209b
Domain Architecture
Description	CD209 antigen-like protein B (DC-SIGN-related protein 1) (DC-SIGNR1) (OtB7).

REG4_HUMAN
NC score	0.146405 (rank : 89)	θ value	1.81305 (rank : 93)
Query Neighborhood Hits	127	Target Neighborhood Hits	105	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BYZ8, Q8NER6, Q8NER7	Gene names	REG4, GISP, RELP
Domain Architecture	No domain graphic available
Description	Regenerating islet-derived protein 4 precursor (Reg IV) (REG-like protein) (Gastrointestinal secretory protein).

ATRN_HUMAN
NC score	0.145953 (rank : 90)	θ value	0.0330416 (rank : 48)
Query Neighborhood Hits	127	Target Neighborhood Hits	525	Shared Neighborhood Hits	62
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

CLC4D_HUMAN
NC score	0.145393 (rank : 91)	θ value	3.0926 (rank : 100)
Query Neighborhood Hits	127	Target Neighborhood Hits	111	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WXI8, Q8N5J5	Gene names	CLEC4D, CLECSF8, MCL
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member D (C-type lectin superfamily member 8) (C-type lectin-like receptor 6) (CLEC-6).

GLU2B_MOUSE
NC score	0.145290 (rank : 92)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	127	Target Neighborhood Hits	357	Shared Neighborhood Hits	40
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

ASGR1_MOUSE
NC score	0.144185 (rank : 93)	θ value	2.36792 (rank : 94)
Query Neighborhood Hits	127	Target Neighborhood Hits	135	Shared Neighborhood Hits	39
SwissProt Accessions	P34927, Q64363	Gene names	Asgr1, Asgr-1
Domain Architecture
Description	Asialoglycoprotein receptor 1 (ASGPR 1) (ASGP-R 1) (Hepatic lectin 1) (MHL-1).

ATRN_MOUSE
NC score	0.143623 (rank : 94)	θ value	0.0330416 (rank : 49)
Query Neighborhood Hits	127	Target Neighborhood Hits	519	Shared Neighborhood Hits	57
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

CSPG2_MOUSE
NC score	0.141958 (rank : 95)	θ value	0.0961366 (rank : 58)
Query Neighborhood Hits	127	Target Neighborhood Hits	711	Shared Neighborhood Hits	60
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CSPG2_HUMAN
NC score	0.141687 (rank : 96)	θ value	0.0961366 (rank : 57)
Query Neighborhood Hits	127	Target Neighborhood Hits	681	Shared Neighborhood Hits	60
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

REG4_MOUSE
NC score	0.138965 (rank : 97)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	127	Target Neighborhood Hits	101	Shared Neighborhood Hits	38
SwissProt Accessions	Q9D8G5, Q3TS25, Q9D858	Gene names	Reg4
Domain Architecture	No domain graphic available
Description	Regenerating islet-derived protein 4 precursor.

CLC4C_HUMAN
NC score	0.138259 (rank : 98)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	127	Target Neighborhood Hits	111	Shared Neighborhood Hits	38
SwissProt Accessions	Q8WTT0, Q3T1C3, Q6UXS8, Q8WXX8	Gene names	CLEC4C, BDCA2, CLECSF11, CLECSF7, DLEC, HECL
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member C (C-type lectin superfamily member 7) (Blood dendritic cell antigen 2 protein) (BDCA-2) (Dendritic lectin) (CD303 antigen).

ASGR1_HUMAN
NC score	0.136951 (rank : 99)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	127	Target Neighborhood Hits	137	Shared Neighborhood Hits	39
SwissProt Accessions	P07306	Gene names	ASGR1
Domain Architecture
Description	Asialoglycoprotein receptor 1 (ASGPR 1) (ASGP-R 1) (Hepatic lectin H1).

CO7_HUMAN
NC score	0.135457 (rank : 100)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	127	Target Neighborhood Hits	278	Shared Neighborhood Hits	59
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CLC4D_MOUSE
NC score	0.134936 (rank : 101)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	127	Target Neighborhood Hits	104	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z2H6, Q8C212	Gene names	Clec4d, Clecsf8, Mcl
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member D (C-type lectin superfamily member 8) (Macrophage-restricted C-type lectin).

KLRBB_MOUSE
NC score	0.133084 (rank : 102)	θ value	1.81305 (rank : 91)
Query Neighborhood Hits	127	Target Neighborhood Hits	105	Shared Neighborhood Hits	39
SwissProt Accessions	P27812	Gene names	Klrb1b, Ly55-b, Ly55b
Domain Architecture
Description	Natural killer cell surface protein P1-34 (NKR-P1 34).

TRBM_MOUSE
NC score	0.133054 (rank : 103)	θ value	4.03905 (rank : 108)
Query Neighborhood Hits	127	Target Neighborhood Hits	361	Shared Neighborhood Hits	51
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

CLC4E_HUMAN
NC score	0.132901 (rank : 104)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	127	Target Neighborhood Hits	104	Shared Neighborhood Hits	36
SwissProt Accessions	Q9ULY5	Gene names	CLEC4E, CLECSF9, MINCLE
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member E (C-type lectin superfamily member 9) (Macrophage-inducible C-type lectin).

C209E_MOUSE
NC score	0.132402 (rank : 105)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	127	Target Neighborhood Hits	117	Shared Neighborhood Hits	38
SwissProt Accessions	Q91ZW7	Gene names	Cd209e
Domain Architecture
Description	CD209 antigen-like protein E (DC-SIGN-related protein 4) (DC-SIGNR4).

CLC4A_MOUSE
NC score	0.131202 (rank : 106)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	127	Target Neighborhood Hits	103	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QZ15, Q4VA33	Gene names	Clec4a, Clec4a2, Clecsf6, Dcir
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member A (C-type lectin superfamily member 6) (Dendritic cell immunoreceptor).

FCER2_HUMAN
NC score	0.129678 (rank : 107)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	127	Target Neighborhood Hits	213	Shared Neighborhood Hits	39
SwissProt Accessions	P06734	Gene names	FCER2, IGEBF
Domain Architecture
Description	Low affinity immunoglobulin epsilon Fc receptor (Lymphocyte IgE receptor) (Fc-epsilon-RII) (BLAST-2) (Immunoglobulin E-binding factor) (CD23 antigen) [Contains: Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form].

CLC4G_MOUSE
NC score	0.129570 (rank : 108)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	127	Target Neighborhood Hits	155	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BNX1, Q5I0T7, Q8R188	Gene names	Clec4g
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member G.

NKG2D_HUMAN
NC score	0.129438 (rank : 109)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	127	Target Neighborhood Hits	98	Shared Neighborhood Hits	37
SwissProt Accessions	P26718, Q9NR41	Gene names	KLRK1, NKG2D
Domain Architecture
Description	NKG2-D type II integral membrane protein (NKG2-D-activating NK receptor) (NK cell receptor D) (Killer cell lectin-like receptor subfamily K member 1) (CD314 antigen).

CLC4G_HUMAN
NC score	0.128212 (rank : 110)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	127	Target Neighborhood Hits	141	Shared Neighborhood Hits	36
SwissProt Accessions	Q6UXB4	Gene names	CLEC4G
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member G.

REG3A_HUMAN
NC score	0.128100 (rank : 111)	θ value	4.03905 (rank : 107)
Query Neighborhood Hits	127	Target Neighborhood Hits	87	Shared Neighborhood Hits	40
SwissProt Accessions	Q06141	Gene names	REG3A, HIP, PAP, PAP1
Domain Architecture
Description	Regenerating islet-derived protein 3 alpha precursor (Reg III-alpha) (Pancreatitis-associated protein 1).

MMGL_MOUSE
NC score	0.126329 (rank : 112)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	127	Target Neighborhood Hits	270	Shared Neighborhood Hits	37
SwissProt Accessions	P49300	Gene names	Mgl1, Mgl
Domain Architecture
Description	Macrophage asialoglycoprotein-binding protein 1 (M-ASGP-BP) (Macrophage galactose/N-acetylgalactosamine-specific lectin) (MMGL).

CD209_HUMAN
NC score	0.125821 (rank : 113)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	127	Target Neighborhood Hits	244	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NNX6, Q96QP7, Q96QP8, Q96QP9, Q96QQ0, Q96QQ1, Q96QQ2, Q96QQ3, Q96QQ4, Q96QQ5, Q96QQ6, Q96QQ7, Q96QQ8	Gene names	CD209, CLEC4L
Domain Architecture
Description	CD209 antigen (Dendritic cell-specific ICAM-3-grabbing nonintegrin 1) (DC-SIGN1) (DC-SIGN) (C-type lectin domain family 4 member L).

FCER2_MOUSE
NC score	0.124191 (rank : 114)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	127	Target Neighborhood Hits	392	Shared Neighborhood Hits	39
SwissProt Accessions	P20693, Q61556, Q61557	Gene names	Fcer2, Fcer2a
Domain Architecture
Description	Low affinity immunoglobulin epsilon Fc receptor (Lymphocyte IGE receptor) (Fc-epsilon-RII) (CD23 antigen).

PGCB_HUMAN
NC score	0.123714 (rank : 115)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	127	Target Neighborhood Hits	478	Shared Neighborhood Hits	49
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

TRBM_HUMAN
NC score	0.123441 (rank : 116)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	127	Target Neighborhood Hits	339	Shared Neighborhood Hits	45
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

PGCB_MOUSE
NC score	0.123129 (rank : 117)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	127	Target Neighborhood Hits	459	Shared Neighborhood Hits	50
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

LIT2_MOUSE
NC score	0.122906 (rank : 118)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	127	Target Neighborhood Hits	111	Shared Neighborhood Hits	35
SwissProt Accessions	Q08731	Gene names	Reg2
Domain Architecture
Description	Lithostathine 2 precursor (Pancreatic stone protein 2) (PSP) (Pancreatic thread protein 2) (PTP) (Islet of Langerhans regenerating protein 2) (REG 2).

KLRF1_HUMAN
NC score	0.122536 (rank : 119)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	127	Target Neighborhood Hits	100	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NZS2, Q96PR2, Q96PR3, Q9NZS1	Gene names	KLRF1, ML
Domain Architecture
Description	Killer cell lectin-like receptor subfamily F member 1 (Lectin-like receptor F1) (Activating coreceptor NKp80).

RXFP2_HUMAN
NC score	0.122524 (rank : 120)	θ value	0.00869519 (rank : 41)
Query Neighborhood Hits	127	Target Neighborhood Hits	736	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WXD0	Gene names	RXFP2, GPR106, GREAT, LGR8
Domain Architecture
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-rich repeat-containing G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106).

REG1A_HUMAN
NC score	0.122188 (rank : 121)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	127	Target Neighborhood Hits	112	Shared Neighborhood Hits	37
SwissProt Accessions	P05451, P11379	Gene names	REG1A, PSPS, REG
Domain Architecture
Description	Lithostathine 1 alpha precursor (Pancreatic stone protein) (PSP) (Pancreatic thread protein) (PTP) (Islet of Langerhans regenerating protein) (REG) (Regenerating protein I alpha) (Islet cells regeneration factor) (ICRF).

CLC4K_HUMAN
NC score	0.120621 (rank : 122)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	127	Target Neighborhood Hits	172	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UJ71	Gene names	CD207, CLEC4K
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member K (Langerin) (CD207 antigen).

REG3G_MOUSE
NC score	0.120089 (rank : 123)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	127	Target Neighborhood Hits	91	Shared Neighborhood Hits	37
SwissProt Accessions	O09049	Gene names	Reg3g, Pap3
Domain Architecture
Description	Regenerating islet-derived protein 3 gamma precursor (Reg III-gamma) (Pancreatitis-associated protein 3).

CD302_MOUSE
NC score	0.119442 (rank : 124)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	127	Target Neighborhood Hits	59	Shared Neighborhood Hits	26
SwissProt Accessions	Q9DCG2, Q78KD8, Q9D0X7	Gene names	Cd302, Clec13a
Domain Architecture	No domain graphic available
Description	CD302 antigen precursor (C-type lectin domain family 13 member A) (Type I transmembrane C-type lectin receptor DCL-1).

TMPS9_HUMAN
NC score	0.118996 (rank : 125)	θ value	2.36792 (rank : 98)
Query Neighborhood Hits	127	Target Neighborhood Hits	276	Shared Neighborhood Hits	57
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

GRN_HUMAN
NC score	0.118982 (rank : 126)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	127	Target Neighborhood Hits	268	Shared Neighborhood Hits	38
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

LIT1_MOUSE
NC score	0.117599 (rank : 127)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	127	Target Neighborhood Hits	114	Shared Neighborhood Hits	36
SwissProt Accessions	P43137	Gene names	Reg1
Domain Architecture
Description	Lithostathine 1 precursor (Pancreatic stone protein 1) (PSP) (Pancreatic thread protein 1) (PTP) (Islet of Langerhans regenerating protein 1) (REG 1).

CD69_HUMAN
NC score	0.117261 (rank : 128)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	127	Target Neighborhood Hits	99	Shared Neighborhood Hits	38
SwissProt Accessions	Q07108	Gene names	CD69
Domain Architecture
Description	Early activation antigen CD69 (Early T-cell activation antigen p60) (GP32/28) (Leu-23) (MLR-3) (EA1) (BL-AC/P26) (Activation inducer molecule) (AIM).

REG3B_MOUSE
NC score	0.115851 (rank : 129)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	127	Target Neighborhood Hits	87	Shared Neighborhood Hits	36
SwissProt Accessions	P35230	Gene names	Reg3b, Pap, Pap1
Domain Architecture
Description	Regenerating islet-derived protein 3 beta precursor (Reg III-beta) (Pancreatitis-associated protein 1).

CLC4K_MOUSE
NC score	0.115627 (rank : 130)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	127	Target Neighborhood Hits	165	Shared Neighborhood Hits	36
SwissProt Accessions	Q8VBX4, Q8R442	Gene names	Cd207, Clec4k
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member K (Langerin) (CD207 antigen).

NKG2D_MOUSE
NC score	0.114860 (rank : 131)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	127	Target Neighborhood Hits	102	Shared Neighborhood Hits	36
SwissProt Accessions	O54709	Gene names	Klrk1, Nkg2d
Domain Architecture
Description	NKG2-D type II integral membrane protein (NKG2-D-activating NK receptor) (NK cell receptor D) (Killer cell lectin-like receptor subfamily K member 1) (CD314 antigen).

SCUB3_HUMAN
NC score	0.114447 (rank : 132)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	127	Target Neighborhood Hits	428	Shared Neighborhood Hits	52
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

C1QR1_HUMAN
NC score	0.114341 (rank : 133)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	127	Target Neighborhood Hits	493	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

CRDL2_HUMAN
NC score	0.114219 (rank : 134)	θ value	0.0431538 (rank : 52)
Query Neighborhood Hits	127	Target Neighborhood Hits	99	Shared Neighborhood Hits	14
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

SCUB3_MOUSE
NC score	0.113986 (rank : 135)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	127	Target Neighborhood Hits	442	Shared Neighborhood Hits	52
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

CD302_HUMAN
NC score	0.113858 (rank : 136)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	127	Target Neighborhood Hits	58	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IX05, Q15009	Gene names	CD302, CLEC13A, DCL1, KIAA0022
Domain Architecture	No domain graphic available
Description	CD302 antigen precursor (C-type lectin domain family 13 member A) (C- type lectin BIMLEC) (Type I transmembrane C-type lectin receptor DCL- 1).

TMPS9_MOUSE
NC score	0.112995 (rank : 137)	θ value	1.38821 (rank : 86)
Query Neighborhood Hits	127	Target Neighborhood Hits	296	Shared Neighborhood Hits	52
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

CD69_MOUSE
NC score	0.112905 (rank : 138)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	127	Target Neighborhood Hits	92	Shared Neighborhood Hits	35
SwissProt Accessions	P37217	Gene names	Cd69
Domain Architecture	No domain graphic available
Description	Early activation antigen CD69.

CRDL2_MOUSE
NC score	0.111820 (rank : 139)	θ value	0.0736092 (rank : 55)
Query Neighborhood Hits	127	Target Neighborhood Hits	81	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

REG3G_HUMAN
NC score	0.110987 (rank : 140)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	127	Target Neighborhood Hits	86	Shared Neighborhood Hits	39
SwissProt Accessions	Q6UW15, Q6FH18	Gene names	REG3G, PAP1B
Domain Architecture	No domain graphic available
Description	Regenerating islet-derived protein 3 gamma precursor (Reg III-gamma) (Pancreatitis-associated protein 1B) (PAP IB).

REG3A_MOUSE
NC score	0.110653 (rank : 141)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	127	Target Neighborhood Hits	80	Shared Neighborhood Hits	34
SwissProt Accessions	O09037	Gene names	Reg3a, Pap2
Domain Architecture
Description	Regenerating islet-derived protein 3 alpha precursor (Reg III-alpha) (Pancreatitis-associated protein 2) (Lithostathine 3) (Islet of Langerhans regenerating protein 3).

GAS6_MOUSE
NC score	0.108890 (rank : 142)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	127	Target Neighborhood Hits	343	Shared Neighborhood Hits	35
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

KLRD1_HUMAN
NC score	0.108825 (rank : 143)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	127	Target Neighborhood Hits	101	Shared Neighborhood Hits	35
SwissProt Accessions	Q13241, O43321, O43773, Q9UBE3, Q9UEQ0	Gene names	KLRD1, CD94
Domain Architecture
Description	Natural killer cells antigen CD94 (NK cell receptor) (Killer cell lectin-like receptor subfamily D member 1) (KP43).

C1QR1_MOUSE
NC score	0.108514 (rank : 144)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	127	Target Neighborhood Hits	342	Shared Neighborhood Hits	41
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

ZAN_MOUSE
NC score	0.108322 (rank : 145)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	127	Target Neighborhood Hits	808	Shared Neighborhood Hits	57
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

CLC9A_HUMAN
NC score	0.108015 (rank : 146)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	127	Target Neighborhood Hits	95	Shared Neighborhood Hits	36
SwissProt Accessions	Q6UXN8	Gene names	CLEC9A
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 9 member A.

TMPS3_HUMAN
NC score	0.107813 (rank : 147)	θ value	0.0330416 (rank : 51)
Query Neighborhood Hits	127	Target Neighborhood Hits	245	Shared Neighborhood Hits	58
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

CLC5A_HUMAN
NC score	0.107339 (rank : 148)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	127	Target Neighborhood Hits	89	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NY25, Q9UKQ0	Gene names	CLEC5A, CLECSF5, MDL1
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 5 member A (C-type lectin superfamily member 5) (Myeloid DAP12-associating lectin) (MDL-1).

OLR1_HUMAN
NC score	0.107096 (rank : 149)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	127	Target Neighborhood Hits	152	Shared Neighborhood Hits	36
SwissProt Accessions	P78380, Q2PP00, Q7Z484	Gene names	OLR1, LOX1
Domain Architecture	No domain graphic available
Description	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) (hLOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, soluble form].

PROS_HUMAN
NC score	0.106699 (rank : 150)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	127	Target Neighborhood Hits	340	Shared Neighborhood Hits	41
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

KLRBC_MOUSE
NC score	0.106467 (rank : 151)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	127	Target Neighborhood Hits	101	Shared Neighborhood Hits	34
SwissProt Accessions	P27814	Gene names	Klrb1c, Ly55-c, Ly55c
Domain Architecture
Description	Natural killer cell surface protein P1-40 (NKR-P1 40) (NKR-P1.9).

PGCA_MOUSE
NC score	0.106261 (rank : 152)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	127	Target Neighborhood Hits	643	Shared Neighborhood Hits	45
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

RXFP2_MOUSE
NC score	0.105453 (rank : 153)	θ value	0.0736092 (rank : 56)
Query Neighborhood Hits	127	Target Neighborhood Hits	760	Shared Neighborhood Hits	57
SwissProt Accessions	Q91ZZ5	Gene names	Rxfp2, Gpr106, Great, Lgr8
Domain Architecture
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-rich repeat-containing G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106).

CLC5A_MOUSE
NC score	0.105437 (rank : 154)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	127	Target Neighborhood Hits	90	Shared Neighborhood Hits	34
SwissProt Accessions	Q9R007, Q3UV97, Q8BL24	Gene names	Clec5a, Clecsf5, Mdl1
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 5 member A (C-type lectin superfamily member 5) (Myeloid DAP12-associating lectin protein) (MDL-1).

CLC9A_MOUSE
NC score	0.105399 (rank : 155)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	127	Target Neighborhood Hits	97	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BRU4	Gene names	Clec9a
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 9 member A.

GAS6_HUMAN
NC score	0.105217 (rank : 156)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	127	Target Neighborhood Hits	348	Shared Neighborhood Hits	40
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

KLRBA_MOUSE
NC score	0.104843 (rank : 157)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	127	Target Neighborhood Hits	104	Shared Neighborhood Hits	35
SwissProt Accessions	P27811	Gene names	Klrb1a, Ly55, Ly55a
Domain Architecture
Description	Natural killer cell surface protein P1-2 (NKR-P1 2) (NKR-P1.7).

CHRD_HUMAN
NC score	0.104575 (rank : 158)	θ value	0.125558 (rank : 61)
Query Neighborhood Hits	127	Target Neighborhood Hits	102	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

CLC2B_HUMAN
NC score	0.104432 (rank : 159)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	127	Target Neighborhood Hits	90	Shared Neighborhood Hits	34
SwissProt Accessions	Q92478, Q8IZE9, Q9BS74, Q9UQB4	Gene names	CLEC2B, AICL, CLECSF2, IFNRG1
Domain Architecture
Description	C-type lectin domain family 2 member B (C-type lectin superfamily member 2) (Activation-induced C-type lectin) (IFN-alpha2b-inducing- related protein 1) (C-type lectin domain family 2 member B).

PROZ_HUMAN
NC score	0.104382 (rank : 160)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	127	Target Neighborhood Hits	422	Shared Neighborhood Hits	48
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

TETN_HUMAN
NC score	0.103538 (rank : 161)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	127	Target Neighborhood Hits	90	Shared Neighborhood Hits	35
SwissProt Accessions	P05452	Gene names	CLEC3B, TNA
Domain Architecture
Description	Tetranectin precursor (TN) (C-type lectin domain family 3 member B) (Plasminogen kringle 4-binding protein).

CLC1A_HUMAN
NC score	0.103317 (rank : 162)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	127	Target Neighborhood Hits	91	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NC01, Q8IUW7, Q9NZH3	Gene names	CLEC1A, CLEC1
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 1 member A (C-type lectin-like receptor 1) (CLEC-1).

CHODL_HUMAN
NC score	0.103161 (rank : 163)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	127	Target Neighborhood Hits	81	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H9P2, Q7Z798, Q7Z799, Q7Z7A0, Q9HCY3	Gene names	CHODL, C21orf68
Domain Architecture
Description	Chondrolectin precursor (Transmembrane protein MT75).

FBN1_MOUSE
NC score	0.102347 (rank : 164)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	127	Target Neighborhood Hits	563	Shared Neighborhood Hits	55
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

TMPS3_MOUSE
NC score	0.102256 (rank : 165)	θ value	0.0961366 (rank : 60)
Query Neighborhood Hits	127	Target Neighborhood Hits	239	Shared Neighborhood Hits	52
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

PROS_MOUSE
NC score	0.101354 (rank : 166)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	127	Target Neighborhood Hits	330	Shared Neighborhood Hits	37
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

OLR1_MOUSE
NC score	0.101320 (rank : 167)	θ value	0.62314 (rank : 78)
Query Neighborhood Hits	127	Target Neighborhood Hits	596	Shared Neighborhood Hits	38
SwissProt Accessions	Q9EQ09	Gene names	Olr1, Lox1
Domain Architecture	No domain graphic available
Description	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, soluble form].

PGCA_HUMAN
NC score	0.100605 (rank : 168)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	127	Target Neighborhood Hits	821	Shared Neighborhood Hits	54
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

TMPS2_MOUSE
NC score	0.100358 (rank : 169)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	127	Target Neighborhood Hits	243	Shared Neighborhood Hits	56
SwissProt Accessions	Q9JIQ8, Q9JKC4, Q9QY82	Gene names	Tmprss2
Domain Architecture
Description	Transmembrane protease, serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

NETO2_HUMAN
NC score	0.100121 (rank : 170)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	127	Target Neighborhood Hits	109	Shared Neighborhood Hits	45
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
NC score	0.099567 (rank : 171)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	127	Target Neighborhood Hits	113	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

FREM1_HUMAN
NC score	0.099564 (rank : 172)	θ value	0.21417 (rank : 65)
Query Neighborhood Hits	127	Target Neighborhood Hits	170	Shared Neighborhood Hits	41
SwissProt Accessions	Q5H8C1, Q5VV00, Q5VV01, Q6MZI4, Q8NEG9, Q96LI3	Gene names	FREM1, C9orf154
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

FBLN2_HUMAN
NC score	0.099345 (rank : 173)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	127	Target Neighborhood Hits	392	Shared Neighborhood Hits	49
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN1_MOUSE
NC score	0.098678 (rank : 174)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	127	Target Neighborhood Hits	329	Shared Neighborhood Hits	41
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

NETO1_MOUSE
NC score	0.098585 (rank : 175)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	127	Target Neighborhood Hits	109	Shared Neighborhood Hits	47
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

FBN3_HUMAN
NC score	0.098453 (rank : 176)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	127	Target Neighborhood Hits	543	Shared Neighborhood Hits	48
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

NETO1_HUMAN
NC score	0.098287 (rank : 177)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	127	Target Neighborhood Hits	110	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

FBLN2_MOUSE
NC score	0.098243 (rank : 178)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	127	Target Neighborhood Hits	505	Shared Neighborhood Hits	51
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBN1_HUMAN
NC score	0.098150 (rank : 179)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	127	Target Neighborhood Hits	557	Shared Neighborhood Hits	50
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

CHODL_MOUSE
NC score	0.097717 (rank : 180)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	127	Target Neighborhood Hits	80	Shared Neighborhood Hits	29
SwissProt Accessions	Q9CXM0, Q8VI31	Gene names	Chodl
Domain Architecture
Description	Chondrolectin precursor (Transmembrane protein MT75).

FBN2_HUMAN
NC score	0.096717 (rank : 181)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	127	Target Neighborhood Hits	560	Shared Neighborhood Hits	50
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
NC score	0.096037 (rank : 182)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	127	Target Neighborhood Hits	549	Shared Neighborhood Hits	50
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

TLL1_MOUSE
NC score	0.095684 (rank : 183)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	127	Target Neighborhood Hits	237	Shared Neighborhood Hits	39
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL1_HUMAN
NC score	0.095434 (rank : 184)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	127	Target Neighborhood Hits	236	Shared Neighborhood Hits	39
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

LTB1S_HUMAN
NC score	0.095112 (rank : 185)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	127	Target Neighborhood Hits	502	Shared Neighborhood Hits	49
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

FBLN1_HUMAN
NC score	0.095098 (rank : 186)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	127	Target Neighborhood Hits	324	Shared Neighborhood Hits	41
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

LTB1L_HUMAN
NC score	0.094983 (rank : 187)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	127	Target Neighborhood Hits	553	Shared Neighborhood Hits	52
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

CUBN_MOUSE
NC score	0.094649 (rank : 188)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	127	Target Neighborhood Hits	477	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

PROC_MOUSE
NC score	0.094582 (rank : 189)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	127	Target Neighborhood Hits	426	Shared Neighborhood Hits	48
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROZ_MOUSE
NC score	0.093740 (rank : 190)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	127	Target Neighborhood Hits	410	Shared Neighborhood Hits	44
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

MEGF6_HUMAN
NC score	0.093657 (rank : 191)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	127	Target Neighborhood Hits	671	Shared Neighborhood Hits	50
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

CLC3A_MOUSE
NC score	0.093220 (rank : 192)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	127	Target Neighborhood Hits	95	Shared Neighborhood Hits	34
SwissProt Accessions	Q9EPW4	Gene names	Clec3a, Clecsf1
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 3 member A precursor (C-type lectin superfamily member 1) (Cartilage-derived C-type lectin).

CLC4F_MOUSE
NC score	0.093115 (rank : 193)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	127	Target Neighborhood Hits	572	Shared Neighborhood Hits	37
SwissProt Accessions	P70194, Q8BLZ8	Gene names	Clec4f, Clecsf13, Kclr
Domain Architecture
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13) (Kupffer cell receptor).

TENA_HUMAN
NC score	0.093019 (rank : 194)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	127	Target Neighborhood Hits	631	Shared Neighborhood Hits	49
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TETN_MOUSE
NC score	0.092949 (rank : 195)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	127	Target Neighborhood Hits	77	Shared Neighborhood Hits	29
SwissProt Accessions	P43025	Gene names	Clec3b, Tna
Domain Architecture
Description	Tetranectin precursor (TN) (C-type lectin domain family 3 member B) (Plasminogen kringle 4-binding protein).

CRIM1_HUMAN
NC score	0.092359 (rank : 196)	θ value	0.47712 (rank : 75)
Query Neighborhood Hits	127	Target Neighborhood Hits	362	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

TLL2_HUMAN
NC score	0.092277 (rank : 197)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	127	Target Neighborhood Hits	241	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

BMP1_MOUSE
NC score	0.092160 (rank : 198)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	127	Target Neighborhood Hits	236	Shared Neighborhood Hits	38
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

TLL2_MOUSE
NC score	0.091990 (rank : 199)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	127	Target Neighborhood Hits	240	Shared Neighborhood Hits	40
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TENA_MOUSE
NC score	0.091819 (rank : 200)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	127	Target Neighborhood Hits	596	Shared Neighborhood Hits	54
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

CLC3A_HUMAN
NC score	0.091692 (rank : 201)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	127	Target Neighborhood Hits	89	Shared Neighborhood Hits	33
SwissProt Accessions	O75596, Q6UXF5	Gene names	CLEC3A, CLECSF1
Domain Architecture
Description	C-type lectin domain family 3 member A precursor (C-type lectin superfamily member 1) (Cartilage-derived C-type lectin).

LTBP2_HUMAN
NC score	0.091420 (rank : 202)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	127	Target Neighborhood Hits	552	Shared Neighborhood Hits	47
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

BMP1_HUMAN
NC score	0.091094 (rank : 203)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	127	Target Neighborhood Hits	233	Shared Neighborhood Hits	38
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

FBLN5_HUMAN
NC score	0.090647 (rank : 204)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	127	Target Neighborhood Hits	329	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

JAG2_MOUSE
NC score	0.090290 (rank : 205)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	127	Target Neighborhood Hits	504	Shared Neighborhood Hits	51
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

LTB1S_MOUSE
NC score	0.089283 (rank : 206)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	127	Target Neighborhood Hits	479	Shared Neighborhood Hits	46
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_MOUSE
NC score	0.089257 (rank : 207)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	127	Target Neighborhood Hits	514	Shared Neighborhood Hits	49
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

CHRD_MOUSE
NC score	0.089127 (rank : 208)	θ value	0.47712 (rank : 73)
Query Neighborhood Hits	127	Target Neighborhood Hits	102	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

TMPS2_HUMAN
NC score	0.089071 (rank : 209)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	127	Target Neighborhood Hits	252	Shared Neighborhood Hits	48
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

FBLN5_MOUSE
NC score	0.089059 (rank : 210)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	127	Target Neighborhood Hits	317	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

NELL2_HUMAN
NC score	0.088893 (rank : 211)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	127	Target Neighborhood Hits	449	Shared Neighborhood Hits	49
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

LTBP4_MOUSE
NC score	0.088842 (rank : 212)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	127	Target Neighborhood Hits	607	Shared Neighborhood Hits	47
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

FA9_HUMAN
NC score	0.088538 (rank : 213)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	127	Target Neighborhood Hits	421	Shared Neighborhood Hits	51
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

NKG2A_HUMAN
NC score	0.088464 (rank : 214)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	127	Target Neighborhood Hits	94	Shared Neighborhood Hits	36
SwissProt Accessions	P26715	Gene names	KLRC1, NKG2A
Domain Architecture
Description	NKG2-A/NKG2-B type II integral membrane protein (NKG2-A/B-activating NK receptor) (NK cell receptor A) (CD159a antigen).

JAG2_HUMAN
NC score	0.088185 (rank : 215)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	127	Target Neighborhood Hits	491	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

NKG2C_HUMAN
NC score	0.087631 (rank : 216)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	127	Target Neighborhood Hits	100	Shared Neighborhood Hits	37
SwissProt Accessions	P26717, O43802, Q9NR42	Gene names	KLRC2, NKG2C
Domain Architecture
Description	NKG2-C type II integral membrane protein (NKG2-C-activating NK receptor) (NK cell receptor C) (CD159c antigen).

NELL2_MOUSE
NC score	0.087302 (rank : 217)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	127	Target Neighborhood Hits	436	Shared Neighborhood Hits	46
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

PROC_HUMAN
NC score	0.086617 (rank : 218)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	127	Target Neighborhood Hits	406	Shared Neighborhood Hits	47
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

CUBN_HUMAN
NC score	0.086532 (rank : 219)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	127	Target Neighborhood Hits	482	Shared Neighborhood Hits	51
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

FA10_MOUSE
NC score	0.086531 (rank : 220)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	127	Target Neighborhood Hits	435	Shared Neighborhood Hits	51
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

EGFL7_HUMAN
NC score	0.086236 (rank : 221)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	127	Target Neighborhood Hits	325	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

FA10_HUMAN
NC score	0.085915 (rank : 222)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	127	Target Neighborhood Hits	431	Shared Neighborhood Hits	49
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

MATN2_HUMAN
NC score	0.085738 (rank : 223)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	127	Target Neighborhood Hits	365	Shared Neighborhood Hits	39
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

GRN_MOUSE
NC score	0.085288 (rank : 224)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	127	Target Neighborhood Hits	248	Shared Neighborhood Hits	34
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

MATN4_HUMAN
NC score	0.084884 (rank : 225)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	127	Target Neighborhood Hits	287	Shared Neighborhood Hits	33
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

NELL1_HUMAN
NC score	0.084780 (rank : 226)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	127	Target Neighborhood Hits	451	Shared Neighborhood Hits	48
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NKG2E_HUMAN
NC score	0.084613 (rank : 227)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	127	Target Neighborhood Hits	96	Shared Neighborhood Hits	35
SwissProt Accessions	Q07444, Q96RL0, Q9UP04	Gene names	KLRC3, NKG2E
Domain Architecture
Description	NKG2-E type II integral membrane protein (NKG2-E-activating NK receptor) (NK cell receptor E).

DLL1_MOUSE
NC score	0.084326 (rank : 228)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	127	Target Neighborhood Hits	456	Shared Neighborhood Hits	48
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

JAG1_MOUSE
NC score	0.083748 (rank : 229)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	127	Target Neighborhood Hits	518	Shared Neighborhood Hits	51
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

HGFA_HUMAN
NC score	0.083460 (rank : 230)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	127	Target Neighborhood Hits	436	Shared Neighborhood Hits	43
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

LTBP2_MOUSE
NC score	0.083380 (rank : 231)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	127	Target Neighborhood Hits	617	Shared Neighborhood Hits	46
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

DLL1_HUMAN
NC score	0.083194 (rank : 232)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	127	Target Neighborhood Hits	455	Shared Neighborhood Hits	52
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

FBLN4_HUMAN
NC score	0.083106 (rank : 233)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	127	Target Neighborhood Hits	278	Shared Neighborhood Hits	36
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FA12_HUMAN
NC score	0.082892 (rank : 234)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	127	Target Neighborhood Hits	425	Shared Neighborhood Hits	37
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

RXFP1_HUMAN
NC score	0.082811 (rank : 235)	θ value	0.21417 (rank : 67)
Query Neighborhood Hits	127	Target Neighborhood Hits	816	Shared Neighborhood Hits	53
SwissProt Accessions	Q9HBX9	Gene names	RXFP1, LGR7
Domain Architecture
Description	Relaxin receptor 1 (Relaxin family peptide receptor 1) (Leucine-rich repeat-containing G-protein coupled receptor 7).

HGFA_MOUSE
NC score	0.082688 (rank : 236)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	127	Target Neighborhood Hits	419	Shared Neighborhood Hits	44
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

LTBP3_MOUSE
NC score	0.082541 (rank : 237)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	127	Target Neighborhood Hits	475	Shared Neighborhood Hits	48
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

JAG1_HUMAN
NC score	0.082323 (rank : 238)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	127	Target Neighborhood Hits	514	Shared Neighborhood Hits	50
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

MASP2_HUMAN
NC score	0.082322 (rank : 239)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	127	Target Neighborhood Hits	364	Shared Neighborhood Hits	44
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MATN3_HUMAN
NC score	0.082245 (rank : 240)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	127	Target Neighborhood Hits	268	Shared Neighborhood Hits	27
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

C1RA_MOUSE
NC score	0.082160 (rank : 241)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	127	Target Neighborhood Hits	379	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

LTBP3_HUMAN
NC score	0.082053 (rank : 242)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	127	Target Neighborhood Hits	502	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

NOTC1_MOUSE
NC score	0.081999 (rank : 243)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	127	Target Neighborhood Hits	916	Shared Neighborhood Hits	53
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

C1RB_MOUSE
NC score	0.081960 (rank : 244)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	127	Target Neighborhood Hits	380	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

MASP1_HUMAN
NC score	0.081884 (rank : 245)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	127	Target Neighborhood Hits	369	Shared Neighborhood Hits	44
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

FBLN4_MOUSE
NC score	0.081869 (rank : 246)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	127	Target Neighborhood Hits	270	Shared Neighborhood Hits	34
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

C1R_HUMAN
NC score	0.081311 (rank : 247)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	127	Target Neighborhood Hits	364	Shared Neighborhood Hits	43
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

MATN4_MOUSE
NC score	0.081181 (rank : 248)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	127	Target Neighborhood Hits	277	Shared Neighborhood Hits	31
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

FA7_HUMAN
NC score	0.081101 (rank : 249)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	127	Target Neighborhood Hits	404	Shared Neighborhood Hits	45
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

FA7_MOUSE
NC score	0.080744 (rank : 250)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	127	Target Neighborhood Hits	374	Shared Neighborhood Hits	42
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

FBLN3_HUMAN
NC score	0.080442 (rank : 251)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	127	Target Neighborhood Hits	293	Shared Neighborhood Hits	37
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

CRUM1_HUMAN
NC score	0.080365 (rank : 252)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	127	Target Neighborhood Hits	457	Shared Neighborhood Hits	45
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CREL1_HUMAN
NC score	0.080236 (rank : 253)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	127	Target Neighborhood Hits	441	Shared Neighborhood Hits	33
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
NC score	0.079620 (rank : 254)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	127	Target Neighborhood Hits	524	Shared Neighborhood Hits	35
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

MATN3_MOUSE
NC score	0.079565 (rank : 255)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	127	Target Neighborhood Hits	261	Shared Neighborhood Hits	28
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MASP1_MOUSE
NC score	0.079102 (rank : 256)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	127	Target Neighborhood Hits	364	Shared Neighborhood Hits	42
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

EGFL8_HUMAN
NC score	0.078702 (rank : 257)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	127	Target Neighborhood Hits	270	Shared Neighborhood Hits	32
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

MASP2_MOUSE
NC score	0.078299 (rank : 258)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	127	Target Neighborhood Hits	382	Shared Neighborhood Hits	44
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

KR107_HUMAN
NC score	0.078243 (rank : 259)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	127	Target Neighborhood Hits	330	Shared Neighborhood Hits	37
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

PHXR5_MOUSE
NC score	0.077652 (rank : 260)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	127	Target Neighborhood Hits	102	Shared Neighborhood Hits	21
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

MATN2_MOUSE
NC score	0.077630 (rank : 261)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	127	Target Neighborhood Hits	356	Shared Neighborhood Hits	38
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

CRUM1_MOUSE
NC score	0.077329 (rank : 262)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	127	Target Neighborhood Hits	444	Shared Neighborhood Hits	48
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

LYAM1_MOUSE
NC score	0.076877 (rank : 263)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	127	Target Neighborhood Hits	332	Shared Neighborhood Hits	46
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

TMPS4_HUMAN
NC score	0.076849 (rank : 264)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	127	Target Neighborhood Hits	203	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NRS4, Q5XKQ6, Q6UX37, Q9NZA5	Gene names	TMPRSS4, TMPRSS3
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Membrane-type serine protease 2) (MT-SP2).

DLL4_HUMAN
NC score	0.076315 (rank : 265)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	127	Target Neighborhood Hits	435	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

NOTC2_HUMAN
NC score	0.076252 (rank : 266)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	127	Target Neighborhood Hits	1113	Shared Neighborhood Hits	55
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

FRAS1_HUMAN
NC score	0.076133 (rank : 267)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	127	Target Neighborhood Hits	759	Shared Neighborhood Hits	41
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

NOTC1_HUMAN
NC score	0.076044 (rank : 268)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	127	Target Neighborhood Hits	906	Shared Neighborhood Hits	49
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

FBLN3_MOUSE
NC score	0.076042 (rank : 269)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	127	Target Neighborhood Hits	279	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

NOTC2_MOUSE
NC score	0.075955 (rank : 270)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	127	Target Neighborhood Hits	1069	Shared Neighborhood Hits	57
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

MBL2_MOUSE
NC score	0.075600 (rank : 271)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	127	Target Neighborhood Hits	148	Shared Neighborhood Hits	29
SwissProt Accessions	P41317	Gene names	Mbl2
Domain Architecture
Description	Mannose-binding protein C precursor (MBP-C) (Mannan-binding protein) (RA-reactive factor P28A subunit) (RARF/P28A).

LYAM1_HUMAN
NC score	0.075321 (rank : 272)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	127	Target Neighborhood Hits	315	Shared Neighborhood Hits	42
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

MBL1_MOUSE
NC score	0.075277 (rank : 273)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	127	Target Neighborhood Hits	147	Shared Neighborhood Hits	28
SwissProt Accessions	P39039	Gene names	Mbl1
Domain Architecture
Description	Mannose-binding protein A precursor (MBP-A) (Mannan-binding protein) (Ra-reactive factor polysaccharide-binding component p28B polypeptide) (RaRF p28B).

CS1B_MOUSE
NC score	0.075268 (rank : 274)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	127	Target Neighborhood Hits	361	Shared Neighborhood Hits	44
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

FREM1_MOUSE
NC score	0.075259 (rank : 275)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	127	Target Neighborhood Hits	163	Shared Neighborhood Hits	36
SwissProt Accessions	Q684R7, Q5H8C2, Q5M7B3, Q8C732	Gene names	Frem1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

STAB2_HUMAN
NC score	0.075025 (rank : 276)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	127	Target Neighborhood Hits	534	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

HABP2_MOUSE
NC score	0.074961 (rank : 277)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	127	Target Neighborhood Hits	445	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

STAB2_MOUSE
NC score	0.074577 (rank : 278)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	127	Target Neighborhood Hits	528	Shared Neighborhood Hits	50
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

KR106_HUMAN
NC score	0.074544 (rank : 279)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	127	Target Neighborhood Hits	347	Shared Neighborhood Hits	39
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

DLL4_MOUSE
NC score	0.074404 (rank : 280)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	127	Target Neighborhood Hits	440	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

PRG3_HUMAN
NC score	0.074026 (rank : 281)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	127	Target Neighborhood Hits	74	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2Y8	Gene names	PRG3, MBPH
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein homolog) (Prepro-major basic protein homolog) (Prepro-MBPH).

NOTC4_HUMAN
NC score	0.073999 (rank : 282)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	127	Target Neighborhood Hits	905	Shared Neighborhood Hits	53
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

EGFL8_MOUSE
NC score	0.073857 (rank : 283)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	127	Target Neighborhood Hits	266	Shared Neighborhood Hits	31
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

PRG3_MOUSE
NC score	0.073765 (rank : 284)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	127	Target Neighborhood Hits	103	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JL95, Q3SXA9	Gene names	Prg3, Mbp2
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein 2).

TMPS4_MOUSE
NC score	0.073720 (rank : 285)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	127	Target Neighborhood Hits	210	Shared Neighborhood Hits	35
SwissProt Accessions	Q8VCA5	Gene names	Tmprss4, Cap2
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (mCAP2).

CS1A_MOUSE
NC score	0.073339 (rank : 286)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	127	Target Neighborhood Hits	360	Shared Neighborhood Hits	44
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

MEGF8_MOUSE
NC score	0.072910 (rank : 287)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	127	Target Neighborhood Hits	520	Shared Neighborhood Hits	49
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

TSG6_MOUSE
NC score	0.072760 (rank : 288)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	127	Target Neighborhood Hits	91	Shared Neighborhood Hits	15
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

C1S_HUMAN
NC score	0.072363 (rank : 289)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	127	Target Neighborhood Hits	359	Shared Neighborhood Hits	43
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

SREC2_HUMAN
NC score	0.072346 (rank : 290)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	127	Target Neighborhood Hits	645	Shared Neighborhood Hits	45
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

CRUM2_HUMAN
NC score	0.072293 (rank : 291)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	127	Target Neighborhood Hits	453	Shared Neighborhood Hits	40
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

TSG6_HUMAN
NC score	0.071801 (rank : 292)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	127	Target Neighborhood Hits	91	Shared Neighborhood Hits	15
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

FRAS1_MOUSE
NC score	0.071793 (rank : 293)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	127	Target Neighborhood Hits	747	Shared Neighborhood Hits	37
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

MEGF8_HUMAN
NC score	0.071480 (rank : 294)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	127	Target Neighborhood Hits	528	Shared Neighborhood Hits	49
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

TENX_HUMAN
NC score	0.071392 (rank : 295)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	127	Target Neighborhood Hits	789	Shared Neighborhood Hits	50
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

STAB1_MOUSE
NC score	0.070998 (rank : 296)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	127	Target Neighborhood Hits	566	Shared Neighborhood Hits	49
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

BMPER_MOUSE
NC score	0.070962 (rank : 297)	θ value	1.38821 (rank : 83)
Query Neighborhood Hits	127	Target Neighborhood Hits	194	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

TMPSD_HUMAN
NC score	0.070933 (rank : 298)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	127	Target Neighborhood Hits	333	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

DLK_HUMAN
NC score	0.070787 (rank : 299)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	127	Target Neighborhood Hits	401	Shared Neighborhood Hits	41
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

SUSD1_HUMAN
NC score	0.070735 (rank : 300)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	127	Target Neighborhood Hits	285	Shared Neighborhood Hits	29
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

NOTC3_HUMAN
NC score	0.070623 (rank : 301)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	127	Target Neighborhood Hits	1062	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

KLRA3_MOUSE
NC score	0.070337 (rank : 302)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	127	Target Neighborhood Hits	90	Shared Neighborhood Hits	34
SwissProt Accessions	Q64329, Q61154, Q64257	Gene names	Klra3, Ly-49c, Ly49C
Domain Architecture
Description	Killer cell lectin-like receptor 3 (T-cell surface glycoprotein Ly- 49C) (Ly49-C antigen) (Lymphocyte antigen 49C) (5E6).

SFTA1_HUMAN
NC score	0.070288 (rank : 303)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	127	Target Neighborhood Hits	169	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IWL2, P07714, Q5RIR5, Q5RIR7, Q6PIT0, Q8TC19	Gene names	SFTPA1, PSAP, SFTP1, SFTPA
Domain Architecture	No domain graphic available
Description	Pulmonary surfactant-associated protein A1 precursor (SP-A1) (SP-A) (PSP-A) (PSPA) (Alveolar proteinosis protein) (35 kDa pulmonary surfactant-associated protein).

STAB1_HUMAN
NC score	0.070206 (rank : 304)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	127	Target Neighborhood Hits	546	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

HABP2_HUMAN
NC score	0.070145 (rank : 305)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	127	Target Neighborhood Hits	431	Shared Neighborhood Hits	33
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

MBL2_HUMAN
NC score	0.069812 (rank : 306)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	127	Target Neighborhood Hits	161	Shared Neighborhood Hits	29
SwissProt Accessions	P11226, Q86SI4, Q96KE4, Q96TF7, Q96TF8, Q96TF9	Gene names	MBL2, MBL
Domain Architecture
Description	Mannose-binding protein C precursor (MBP-C) (MBP1) (Mannan-binding protein) (Mannose-binding lectin).

NOTC3_MOUSE
NC score	0.069695 (rank : 307)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	127	Target Neighborhood Hits	975	Shared Neighborhood Hits	58
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC4_MOUSE
NC score	0.069558 (rank : 308)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	127	Target Neighborhood Hits	872	Shared Neighborhood Hits	53
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

SFTA2_HUMAN
NC score	0.069510 (rank : 309)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	127	Target Neighborhood Hits	169	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IWL1, P07714, Q5RIR8, Q5RIR9	Gene names	SFTPA2, PSAP, SFTP1, SFTPA
Domain Architecture	No domain graphic available
Description	Pulmonary surfactant-associated protein A2 precursor (SP-A2) (SP-A) (PSP-A) (PSPA) (Alveolar proteinosis protein) (35 kDa pulmonary surfactant-associated protein).

KR104_HUMAN
NC score	0.069281 (rank : 310)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	127	Target Neighborhood Hits	313	Shared Neighborhood Hits	33
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

AGRIN_HUMAN
NC score	0.069225 (rank : 311)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	127	Target Neighborhood Hits	582	Shared Neighborhood Hits	45
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

DLL3_HUMAN
NC score	0.068808 (rank : 312)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	127	Target Neighborhood Hits	419	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

HMCN1_HUMAN
NC score	0.068393 (rank : 313)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	127	Target Neighborhood Hits	983	Shared Neighborhood Hits	49
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

KLRA5_MOUSE
NC score	0.068166 (rank : 314)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	127	Target Neighborhood Hits	88	Shared Neighborhood Hits	35
SwissProt Accessions	Q60652	Gene names	Klra5, Ly-49e, Ly49-e, Ly49e
Domain Architecture
Description	Killer cell lectin-like receptor 5 (T-cell surface glycoprotein Ly- 49E) (Ly49-E antigen) (Lymphocyte antigen 49E).

DLK_MOUSE
NC score	0.068082 (rank : 315)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	127	Target Neighborhood Hits	374	Shared Neighborhood Hits	37
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

MUC5B_HUMAN
NC score	0.067960 (rank : 316)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	127	Target Neighborhood Hits	1020	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

EMBP_HUMAN
NC score	0.067728 (rank : 317)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	127	Target Neighborhood Hits	42	Shared Neighborhood Hits	15
SwissProt Accessions	P13727, Q14227	Gene names	PRG2, MBP
Domain Architecture
Description	Eosinophil granule major basic protein precursor (MBP) (EMBP) (Pregnancy-associated major basic protein) (Proteoglycan 2, bone marrow) (BMPG).

TMPSD_MOUSE
NC score	0.067426 (rank : 318)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	127	Target Neighborhood Hits	334	Shared Neighborhood Hits	25
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

SREC2_MOUSE
NC score	0.067280 (rank : 319)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	127	Target Neighborhood Hits	605	Shared Neighborhood Hits	43
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

KLRA4_MOUSE
NC score	0.067022 (rank : 320)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	127	Target Neighborhood Hits	91	Shared Neighborhood Hits	34
SwissProt Accessions	Q60651, O78026, Q9EPA5	Gene names	Klra4, Ly-49d, Ly49-d, Ly49d
Domain Architecture
Description	Killer cell lectin-like receptor 4 (T-cell surface glycoprotein Ly- 49D) (Ly49-D antigen) (Lymphocyte antigen 49D).

KLRA7_MOUSE
NC score	0.067005 (rank : 321)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	127	Target Neighborhood Hits	89	Shared Neighborhood Hits	34
SwissProt Accessions	Q60654, Q60655, Q60656, Q60683	Gene names	Klra7, Ly-49g, Ly49-g, Ly49g, Ly49g4
Domain Architecture
Description	Killer cell lectin-like receptor 7 (T-cell surface glycoprotein Ly- 49G) (Ly49-G antigen) (Lymphocyte antigen 49G).

SREC_HUMAN
NC score	0.067000 (rank : 322)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	127	Target Neighborhood Hits	645	Shared Neighborhood Hits	52
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

LY49A_MOUSE
NC score	0.066746 (rank : 323)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	127	Target Neighborhood Hits	91	Shared Neighborhood Hits	34
SwissProt Accessions	P20937	Gene names	Klra1, Ly-49, Ly-49a, Ly49, Ly49A
Domain Architecture
Description	T-cell surface glycoprotein YE1/48 (T lymphocyte antigen A1) (Ly49-A antigen) (Lymphocyte antigen 49A).

EGFL7_MOUSE
NC score	0.066427 (rank : 324)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	127	Target Neighborhood Hits	287	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

WIF1_HUMAN
NC score	0.066400 (rank : 325)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	127	Target Neighborhood Hits	392	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

TPA_HUMAN
NC score	0.065766 (rank : 326)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	127	Target Neighborhood Hits	324	Shared Neighborhood Hits	34
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TM11E_HUMAN
NC score	0.065560 (rank : 327)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	127	Target Neighborhood Hits	181	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UL52, Q6UW31	Gene names	TMPRSS11E, DESC1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

DNER_HUMAN
NC score	0.065473 (rank : 328)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	127	Target Neighborhood Hits	460	Shared Neighborhood Hits	40
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

CLC14_MOUSE
NC score	0.065318 (rank : 329)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	127	Target Neighborhood Hits	120	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

CD72_MOUSE
NC score	0.065214 (rank : 330)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	127	Target Neighborhood Hits	262	Shared Neighborhood Hits	27
SwissProt Accessions	P21855, Q64225	Gene names	Cd72, Ly-32, Lyb-2
Domain Architecture
Description	B-cell differentiation antigen CD72 (Lyb-2) (Antigen Ly-32).

LCE3B_HUMAN
NC score	0.065178 (rank : 331)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	127	Target Neighborhood Hits	47	Shared Neighborhood Hits	10
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

UROM_HUMAN
NC score	0.064988 (rank : 332)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	127	Target Neighborhood Hits	284	Shared Neighborhood Hits	32
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

TPA_MOUSE
NC score	0.064832 (rank : 333)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	127	Target Neighborhood Hits	335	Shared Neighborhood Hits	35
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

LYAM2_MOUSE
NC score	0.064644 (rank : 334)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	127	Target Neighborhood Hits	420	Shared Neighborhood Hits	51
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

DLL3_MOUSE
NC score	0.064461 (rank : 335)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	127	Target Neighborhood Hits	399	Shared Neighborhood Hits	38
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

KLRA6_MOUSE
NC score	0.064447 (rank : 336)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	127	Target Neighborhood Hits	91	Shared Neighborhood Hits	34
SwissProt Accessions	Q60653	Gene names	Klra6, Ly-49f, Ly49-f, Ly49F
Domain Architecture
Description	Killer cell lectin-like receptor 6 (T-cell surface glycoprotein Ly- 49F) (Ly49-F antigen) (Lymphocyte antigen 49F).

SLIT1_MOUSE
NC score	0.064383 (rank : 337)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	127	Target Neighborhood Hits	715	Shared Neighborhood Hits	53
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

CLC4F_HUMAN
NC score	0.064177 (rank : 338)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	127	Target Neighborhood Hits	513	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N1N0	Gene names	CLEC4F, CLECSF13
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13).

EMBP_MOUSE
NC score	0.064156 (rank : 339)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	127	Target Neighborhood Hits	45	Shared Neighborhood Hits	14
SwissProt Accessions	Q61878	Gene names	Prg2, Mbp-1
Domain Architecture
Description	Eosinophil granule major basic protein precursor (MBP) (Proteoglycan 2, bone marrow).

KRA53_HUMAN
NC score	0.064131 (rank : 340)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	127	Target Neighborhood Hits	331	Shared Neighborhood Hits	30
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

TM11E_MOUSE
NC score	0.063975 (rank : 341)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	127	Target Neighborhood Hits	176	Shared Neighborhood Hits	16
SwissProt Accessions	Q5S248, Q8BM10	Gene names	Tmprss11e, Desc1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

LAMA1_MOUSE
NC score	0.063941 (rank : 342)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	127	Target Neighborhood Hits	838	Shared Neighborhood Hits	44
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

UROM_MOUSE
NC score	0.063826 (rank : 343)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	127	Target Neighborhood Hits	276	Shared Neighborhood Hits	32
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

POLS2_HUMAN
NC score	0.063511 (rank : 344)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	127	Target Neighborhood Hits	192	Shared Neighborhood Hits	17
SwissProt Accessions	Q5K4E3, Q8NBY4	Gene names	PRSS36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

WIF1_MOUSE
NC score	0.063424 (rank : 345)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	127	Target Neighborhood Hits	393	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

TM11D_MOUSE
NC score	0.063364 (rank : 346)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	127	Target Neighborhood Hits	179	Shared Neighborhood Hits	16
SwissProt Accessions	Q8VHK8, Q7TNX3, Q8VDV1	Gene names	Tmprss11d, Mat
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) (AT) (Adrenal secretory serine protease) (AsP) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

TMPS5_HUMAN
NC score	0.063310 (rank : 347)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	127	Target Neighborhood Hits	181	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H3S3	Gene names	TMPRSS5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

DESC4_MOUSE
NC score	0.063169 (rank : 348)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	127	Target Neighborhood Hits	176	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BZ10, Q8BZ04	Gene names	Desc4
Domain Architecture	No domain graphic available
Description	Serine protease DESC4 precursor (EC 3.4.21.-) [Contains: Serine protease DESC4 non-catalytic chain; Serine protease DESC4 catalytic chain].

TMPS5_MOUSE
NC score	0.063052 (rank : 349)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	127	Target Neighborhood Hits	185	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ER04, Q9ER02, Q9ER03	Gene names	Tmprss5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

TEST_HUMAN
NC score	0.062956 (rank : 350)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	127	Target Neighborhood Hits	172	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y6M0, Q9NS34, Q9P2V6	Gene names	PRSS21, ESP1, TEST1
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Eosinophil serine protease 1) (ESP- 1).

HEPS_MOUSE
NC score	0.062813 (rank : 351)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	127	Target Neighborhood Hits	178	Shared Neighborhood Hits	16
SwissProt Accessions	O35453, Q9CW97	Gene names	Hpn
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

KRA59_HUMAN
NC score	0.062693 (rank : 352)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	127	Target Neighborhood Hits	310	Shared Neighborhood Hits	27
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

HEPS_HUMAN
NC score	0.062466 (rank : 353)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	127	Target Neighborhood Hits	178	Shared Neighborhood Hits	16
SwissProt Accessions	P05981	Gene names	HPN, TMPRSS1
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) (Transmembrane protease, serine 1) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

ACRO_HUMAN
NC score	0.062368 (rank : 354)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	127	Target Neighborhood Hits	291	Shared Neighborhood Hits	19
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

POLS2_MOUSE
NC score	0.062159 (rank : 355)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	127	Target Neighborhood Hits	188	Shared Neighborhood Hits	16
SwissProt Accessions	Q5K2P8	Gene names	Prss36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

TM11D_HUMAN
NC score	0.062025 (rank : 356)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	127	Target Neighborhood Hits	176	Shared Neighborhood Hits	16
SwissProt Accessions	O60235	Gene names	TMPRSS11D, HAT
Domain Architecture
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

EDIL3_HUMAN
NC score	0.061734 (rank : 357)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	127	Target Neighborhood Hits	292	Shared Neighborhood Hits	32
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

KRA47_HUMAN
NC score	0.061662 (rank : 358)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	127	Target Neighborhood Hits	204	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KLKB1_MOUSE
NC score	0.061649 (rank : 359)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	127	Target Neighborhood Hits	177	Shared Neighborhood Hits	16
SwissProt Accessions	P26262	Gene names	Klkb1, Klk3, Pk
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

EMR1_HUMAN
NC score	0.061395 (rank : 360)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	127	Target Neighborhood Hits	382	Shared Neighborhood Hits	44
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

FA11_MOUSE
NC score	0.061017 (rank : 361)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	127	Target Neighborhood Hits	180	Shared Neighborhood Hits	16
SwissProt Accessions	Q91Y47	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

LYAM2_HUMAN
NC score	0.060925 (rank : 362)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	127	Target Neighborhood Hits	394	Shared Neighborhood Hits	48
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

PRSS8_MOUSE
NC score	0.060786 (rank : 363)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	127	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ESD1	Gene names	Prss8, Cap1
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) (Channel-activating protease 1) [Contains: Prostasin light chain; Prostasin heavy chain].

FA11_HUMAN
NC score	0.060719 (rank : 364)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	127	Target Neighborhood Hits	178	Shared Neighborhood Hits	16
SwissProt Accessions	P03951, Q9Y495	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

SLIT3_HUMAN
NC score	0.060691 (rank : 365)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	127	Target Neighborhood Hits	682	Shared Neighborhood Hits	45
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

KLKB1_HUMAN
NC score	0.060571 (rank : 366)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	127	Target Neighborhood Hits	183	Shared Neighborhood Hits	16
SwissProt Accessions	P03952	Gene names	KLKB1, KLK3
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

PRS27_HUMAN
NC score	0.060556 (rank : 367)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	127	Target Neighborhood Hits	177	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BQR3	Gene names	PRSS27, MPN
Domain Architecture
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin) (Channel-activating protease 2) (CAPH2).

PRS27_MOUSE
NC score	0.060554 (rank : 368)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	127	Target Neighborhood Hits	175	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BJR6	Gene names	Prss27, Mpn
Domain Architecture	No domain graphic available
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin).

TEST_MOUSE
NC score	0.060494 (rank : 369)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	127	Target Neighborhood Hits	174	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JHJ7, Q9DA14	Gene names	Prss21
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Tryptase 4).

KLRA8_MOUSE
NC score	0.060410 (rank : 370)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	127	Target Neighborhood Hits	90	Shared Neighborhood Hits	33
SwissProt Accessions	Q60682, O78027	Gene names	Klra8, Ly-49h, Ly49-h, Ly49H
Domain Architecture
Description	Killer cell lectin-like receptor 8 (T-cell surface glycoprotein Ly- 49H) (Ly49-H antigen) (Lymphocyte antigen 49H).

UROK_HUMAN
NC score	0.060357 (rank : 371)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	127	Target Neighborhood Hits	272	Shared Neighborhood Hits	28
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

ACRO_MOUSE
NC score	0.060277 (rank : 372)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	127	Target Neighborhood Hits	185	Shared Neighborhood Hits	16
SwissProt Accessions	P23578	Gene names	Acr
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

EGFL9_MOUSE
NC score	0.060221 (rank : 373)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	127	Target Neighborhood Hits	379	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

PCSK5_MOUSE
NC score	0.060047 (rank : 374)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	127	Target Neighborhood Hits	613	Shared Neighborhood Hits	45
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

TSP50_HUMAN
NC score	0.059972 (rank : 375)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	127	Target Neighborhood Hits	178	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UI38	Gene names	TSP50
Domain Architecture
Description	Testis-specific protease-like protein 50 precursor.

PRSS8_HUMAN
NC score	0.059916 (rank : 376)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	127	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	Q16651, Q9UCA3	Gene names	PRSS8
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) [Contains: Prostasin light chain; Prostasin heavy chain].

DNER_MOUSE
NC score	0.059671 (rank : 377)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	127	Target Neighborhood Hits	413	Shared Neighborhood Hits	38
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

LYAM3_HUMAN
NC score	0.059664 (rank : 378)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	127	Target Neighborhood Hits	378	Shared Neighborhood Hits	52
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

TMSP8_MOUSE
NC score	0.059633 (rank : 379)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	127	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QYZ9, Q91XC4	Gene names	Tmprss8, Disp
Domain Architecture
Description	Transmembrane serine protease 8 precursor (EC 3.4.21.-) (Distal intestinal serine protease).

SLIT1_HUMAN
NC score	0.059559 (rank : 380)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	127	Target Neighborhood Hits	700	Shared Neighborhood Hits	48
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

TRYG1_MOUSE
NC score	0.059556 (rank : 381)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	127	Target Neighborhood Hits	181	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QUL7	Gene names	Tpsg1, Tmt
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

TRYG1_HUMAN
NC score	0.059379 (rank : 382)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	127	Target Neighborhood Hits	179	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NRR2, Q96RZ8, Q9C015, Q9NRQ8, Q9UBB2	Gene names	TPSG1, TMT
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

PCOC2_MOUSE
NC score	0.059318 (rank : 383)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	127	Target Neighborhood Hits	73	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

UROK_MOUSE
NC score	0.059304 (rank : 384)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	127	Target Neighborhood Hits	273	Shared Neighborhood Hits	28
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

BSSP4_HUMAN
NC score	0.059281 (rank : 385)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	127	Target Neighborhood Hits	176	Shared Neighborhood Hits	16
SwissProt Accessions	Q9GZN4, O43342, Q6UXE0	Gene names	PRSS22, BSSP4, PRSS26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

EGFL9_HUMAN
NC score	0.059230 (rank : 386)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	127	Target Neighborhood Hits	365	Shared Neighborhood Hits	36
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

TSP1_HUMAN
NC score	0.059186 (rank : 387)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	127	Target Neighborhood Hits	389	Shared Neighborhood Hits	47
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

SLIT2_HUMAN
NC score	0.058704 (rank : 388)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	127	Target Neighborhood Hits	708	Shared Neighborhood Hits	47
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

CTRL_HUMAN
NC score	0.058558 (rank : 389)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	127	Target Neighborhood Hits	179	Shared Neighborhood Hits	16
SwissProt Accessions	P40313	Gene names	CTRL, CTRL1
Domain Architecture
Description	Chymotrypsin-like protease CTRL-1 precursor (EC 3.4.21.-).

CLCR_HUMAN
NC score	0.058522 (rank : 390)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	127	Target Neighborhood Hits	177	Shared Neighborhood Hits	16
SwissProt Accessions	Q99895, O00765, Q9NUH5	Gene names	CTRC, CLCR
Domain Architecture
Description	Caldecrin precursor (EC 3.4.21.2) (Chymotrypsin C).

CTRB1_HUMAN
NC score	0.058487 (rank : 391)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	127	Target Neighborhood Hits	176	Shared Neighborhood Hits	16
SwissProt Accessions	P17538	Gene names	CTRB1, CTRB
Domain Architecture
Description	Chymotrypsinogen B precursor (EC 3.4.21.1) [Contains: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C].

BSSP4_MOUSE
NC score	0.058301 (rank : 392)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	127	Target Neighborhood Hits	179	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ER10	Gene names	Prss22, Bssp4, Prss26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

MCPT6_MOUSE
NC score	0.057864 (rank : 393)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	127	Target Neighborhood Hits	175	Shared Neighborhood Hits	16
SwissProt Accessions	P21845, Q61962	Gene names	Mcpt6
Domain Architecture
Description	Mast cell protease 6 precursor (EC 3.4.21.59) (MMCP-6) (Tryptase).

PCOC2_HUMAN
NC score	0.057433 (rank : 394)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	127	Target Neighborhood Hits	73	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

TENR_MOUSE
NC score	0.057185 (rank : 395)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	127	Target Neighborhood Hits	531	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

ELA2A_MOUSE
NC score	0.057105 (rank : 396)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	127	Target Neighborhood Hits	178	Shared Neighborhood Hits	16
SwissProt Accessions	P05208	Gene names	Ela2a, Ela-2, Ela2
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71) (Elastase-2).

TRYB1_MOUSE
NC score	0.057095 (rank : 397)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	127	Target Neighborhood Hits	175	Shared Neighborhood Hits	16
SwissProt Accessions	Q02844	Gene names	Tpsab1, Mcpt7
Domain Architecture
Description	Tryptase precursor (EC 3.4.21.59) (Mast cell protease 7) (MMCP-7) (Tryptase alpha/beta-1).

TRYB1_HUMAN
NC score	0.056973 (rank : 398)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	127	Target Neighborhood Hits	175	Shared Neighborhood Hits	16
SwissProt Accessions	Q15661, Q15663, Q9H2Y4	Gene names	TPSAB1, TPSB1
Domain Architecture
Description	Tryptase beta-1 precursor (EC 3.4.21.59) (Tryptase-1) (Tryptase I).

TRYB2_HUMAN
NC score	0.056973 (rank : 399)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	127	Target Neighborhood Hits	175	Shared Neighborhood Hits	16
SwissProt Accessions	P20231, O95827, Q15664, Q9UQI6, Q9UQI7	Gene names	TPSB2, TPS2
Domain Architecture
Description	Tryptase beta-2 precursor (EC 3.4.21.59) (Tryptase-2) (Tryptase II).

SLIT2_MOUSE
NC score	0.056792 (rank : 400)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	127	Target Neighborhood Hits	684	Shared Neighborhood Hits	42
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

TSP1_MOUSE
NC score	0.056775 (rank : 401)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	127	Target Neighborhood Hits	396	Shared Neighborhood Hits	47
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

TRYA1_HUMAN
NC score	0.056723 (rank : 402)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	127	Target Neighborhood Hits	177	Shared Neighborhood Hits	16
SwissProt Accessions	P15157, Q9H2Y5, Q9UQI1	Gene names	TPSAB1, TPS1
Domain Architecture
Description	Tryptase alpha-1 precursor (EC 3.4.21.59) (Tryptase-1).

ELA2A_HUMAN
NC score	0.056508 (rank : 403)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	127	Target Neighborhood Hits	180	Shared Neighborhood Hits	16
SwissProt Accessions	P08217, Q14243	Gene names	ELA2A
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71).

NETR_MOUSE
NC score	0.056476 (rank : 404)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	127	Target Neighborhood Hits	216	Shared Neighborhood Hits	17
SwissProt Accessions	O08762	Gene names	Prss12, Bssp3
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Brain-specific serine protease 3) (BSSP-3).

LAMA5_MOUSE
NC score	0.056382 (rank : 405)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	127	Target Neighborhood Hits	828	Shared Neighborhood Hits	49
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

BMPER_HUMAN
NC score	0.056323 (rank : 406)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	127	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

SFTPA_MOUSE
NC score	0.056225 (rank : 407)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	127	Target Neighborhood Hits	169	Shared Neighborhood Hits	26
SwissProt Accessions	P35242	Gene names	Sftpa1, Sftp-1, Sftp1, Sftpa
Domain Architecture
Description	Pulmonary surfactant-associated protein A precursor (SP-A) (PSP-A) (PSAP).

ELA3B_HUMAN
NC score	0.056219 (rank : 408)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	127	Target Neighborhood Hits	175	Shared Neighborhood Hits	16
SwissProt Accessions	P08861, P11423, Q5VU28, Q5VU29, Q5VU30	Gene names	ELA3B
Domain Architecture
Description	Elastase-3B precursor (EC 3.4.21.70) (Elastase IIIB) (Protease E).

ELA2B_HUMAN
NC score	0.056172 (rank : 409)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	127	Target Neighborhood Hits	178	Shared Neighborhood Hits	16
SwissProt Accessions	P08218	Gene names	ELA2B
Domain Architecture
Description	Elastase-2B precursor (EC 3.4.21.71).

TRYD_HUMAN
NC score	0.056129 (rank : 410)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	127	Target Neighborhood Hits	175	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BZJ3, O95824, Q8TDI6, Q96L36, Q96RZ5, Q9H2Y6, Q9UQI8	Gene names	TPSD1
Domain Architecture
Description	Tryptase delta precursor (EC 3.4.21.59) (Delta tryptase) (Mast cell mMCP-7-like) (Tryptase-3) (HmMCP-3-like tryptase III).

EMR2_HUMAN
NC score	0.056106 (rank : 411)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	127	Target Neighborhood Hits	345	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

SLIT3_MOUSE
NC score	0.056012 (rank : 412)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	127	Target Neighborhood Hits	700	Shared Neighborhood Hits	40
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

ELA3A_HUMAN
NC score	0.055975 (rank : 413)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	127	Target Neighborhood Hits	173	Shared Neighborhood Hits	16
SwissProt Accessions	P09093, Q9BRW4	Gene names	ELA3A, ELA3
Domain Architecture
Description	Elastase-3A precursor (EC 3.4.21.70) (Elastase IIIA) (Protease E).

KRA44_HUMAN
NC score	0.055795 (rank : 414)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	127	Target Neighborhood Hits	162	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

PLMN_MOUSE
NC score	0.055703 (rank : 415)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	127	Target Neighborhood Hits	208	Shared Neighborhood Hits	20
SwissProt Accessions	P20918, Q8CIS2, Q91WJ5	Gene names	Plg
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

GRAM_HUMAN
NC score	0.055691 (rank : 416)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	127	Target Neighborhood Hits	174	Shared Neighborhood Hits	16
SwissProt Accessions	P51124	Gene names	GZMM, MET1
Domain Architecture
Description	Granzyme M precursor (EC 3.4.21.-) (Met-ase) (Natural killer cell granular protease) (HU-Met-1) (Met-1 serine protease).

CD97_HUMAN
NC score	0.055499 (rank : 417)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	127	Target Neighborhood Hits	353	Shared Neighborhood Hits	33
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

NETR_HUMAN
NC score	0.055488 (rank : 418)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	127	Target Neighborhood Hits	218	Shared Neighborhood Hits	16
SwissProt Accessions	P56730, Q9UP16	Gene names	PRSS12
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Leydin).

LAMA1_HUMAN
NC score	0.055323 (rank : 419)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	127	Target Neighborhood Hits	804	Shared Neighborhood Hits	44
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

TENR_HUMAN
NC score	0.055287 (rank : 420)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	127	Target Neighborhood Hits	526	Shared Neighborhood Hits	48
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

RECK_HUMAN
NC score	0.055235 (rank : 421)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	127	Target Neighborhood Hits	189	Shared Neighborhood Hits	29
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

THRB_HUMAN
NC score	0.055096 (rank : 422)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	127	Target Neighborhood Hits	196	Shared Neighborhood Hits	16
SwissProt Accessions	P00734	Gene names	F2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

ASTN_MOUSE
NC score	0.055000 (rank : 423)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	127	Target Neighborhood Hits	98	Shared Neighborhood Hits	20
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

HPT_MOUSE
NC score	0.054551 (rank : 424)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	127	Target Neighborhood Hits	178	Shared Neighborhood Hits	16
SwissProt Accessions	Q61646	Gene names	Hp
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

KRA58_HUMAN
NC score	0.054490 (rank : 425)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	127	Target Neighborhood Hits	324	Shared Neighborhood Hits	28
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

ELA1_HUMAN
NC score	0.054470 (rank : 426)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	127	Target Neighborhood Hits	178	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UNI1, Q5MLF0, Q6DJT0, Q6ISM6	Gene names	ELA1
Domain Architecture
Description	Elastase-1 precursor (EC 3.4.21.36).

CRDL1_HUMAN
NC score	0.054403 (rank : 427)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	127	Target Neighborhood Hits	75	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BU40, Q9Y3H7	Gene names	CHRDL1, NRLN1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CRDL1_MOUSE
NC score	0.054341 (rank : 428)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	127	Target Neighborhood Hits	81	Shared Neighborhood Hits	12
SwissProt Accessions	Q920C1, Q924K0, Q9EPZ9	Gene names	Chrdl1, Ng1, Nrln1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

KR10B_HUMAN
NC score	0.054254 (rank : 429)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	127	Target Neighborhood Hits	269	Shared Neighborhood Hits	28
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

LYAM3_MOUSE
NC score	0.054238 (rank : 430)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	127	Target Neighborhood Hits	390	Shared Neighborhood Hits	50
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

KR412_HUMAN
NC score	0.054226 (rank : 431)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	127	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

EDIL3_MOUSE
NC score	0.054216 (rank : 432)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	127	Target Neighborhood Hits	317	Shared Neighborhood Hits	28
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

PLMN_HUMAN
NC score	0.054092 (rank : 433)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	127	Target Neighborhood Hits	204	Shared Neighborhood Hits	16
SwissProt Accessions	P00747, Q15146, Q6PA00	Gene names	PLG
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

TECTA_MOUSE
NC score	0.053768 (rank : 434)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	127	Target Neighborhood Hits	244	Shared Neighborhood Hits	33
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

APOA_HUMAN
NC score	0.053697 (rank : 435)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	127	Target Neighborhood Hits	221	Shared Neighborhood Hits	17
SwissProt Accessions	P08519	Gene names	LPA
Domain Architecture
Description	Apolipoprotein(a) precursor (EC 3.4.21.-) (Apo(a)) (Lp(a)).

THRB_MOUSE
NC score	0.053641 (rank : 436)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	127	Target Neighborhood Hits	195	Shared Neighborhood Hits	16
SwissProt Accessions	P19221	Gene names	F2, Cf2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

KR511_HUMAN
NC score	0.053491 (rank : 437)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	127	Target Neighborhood Hits	231	Shared Neighborhood Hits	19
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

CO2_MOUSE
NC score	0.053267 (rank : 438)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	127	Target Neighborhood Hits	250	Shared Neighborhood Hits	21
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

TRY2_MOUSE
NC score	0.052874 (rank : 439)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	127	Target Neighborhood Hits	174	Shared Neighborhood Hits	16
SwissProt Accessions	P07146	Gene names	Prss2, Try2
Domain Architecture
Description	Anionic trypsin-2 precursor (EC 3.4.21.4) (Anionic trypsin II) (Pretrypsinogen II).

HPT_HUMAN
NC score	0.052869 (rank : 440)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	127	Target Neighborhood Hits	184	Shared Neighborhood Hits	17
SwissProt Accessions	P00738, P00737, Q2PP15, Q3B7J0, Q6LBY9	Gene names	HP
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

ASTN_HUMAN
NC score	0.052786 (rank : 441)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	127	Target Neighborhood Hits	105	Shared Neighborhood Hits	20
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

LAMA5_HUMAN
NC score	0.052662 (rank : 442)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	127	Target Neighborhood Hits	976	Shared Neighborhood Hits	50
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

VTDB_MOUSE
NC score	0.052587 (rank : 443)	θ value	0.813845 (rank : 81)
Query Neighborhood Hits	127	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	P21614, Q7TS97, Q91XG1, Q9CY31	Gene names	Gc
Domain Architecture
Description	Vitamin D-binding protein precursor (DBP) (Group-specific component) (Gc-globulin) (VDB).

TRY1_HUMAN
NC score	0.052494 (rank : 444)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	127	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P07477, Q92955, Q9HAN4, Q9HAN5, Q9HAN6, Q9HAN7	Gene names	PRSS1, TRP1, TRY1, TRYP1
Domain Architecture
Description	Trypsin-1 precursor (EC 3.4.21.4) (Trypsin I) (Cationic trypsinogen).

TRY2_HUMAN
NC score	0.052435 (rank : 445)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	127	Target Neighborhood Hits	175	Shared Neighborhood Hits	16
SwissProt Accessions	P07478	Gene names	PRSS2, TRY2, TRYP2
Domain Architecture
Description	Trypsin-2 precursor (EC 3.4.21.4) (Trypsin II) (Anionic trypsinogen).

CFAD_HUMAN
NC score	0.052336 (rank : 446)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	127	Target Neighborhood Hits	176	Shared Neighborhood Hits	16
SwissProt Accessions	P00746	Gene names	CFD, DF
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin).

EMR1_MOUSE
NC score	0.052218 (rank : 447)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	127	Target Neighborhood Hits	349	Shared Neighborhood Hits	36
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

TRY3_HUMAN
NC score	0.052181 (rank : 448)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	127	Target Neighborhood Hits	178	Shared Neighborhood Hits	16
SwissProt Accessions	P35030, P15951, Q15665, Q9UQV3	Gene names	PRSS3, PRSS4, TRY3, TRY4
Domain Architecture
Description	Trypsin-3 precursor (EC 3.4.21.4) (Trypsin III) (Brain trypsinogen) (Mesotrypsinogen) (Trypsin IV).

HPTR_HUMAN
NC score	0.052133 (rank : 449)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	127	Target Neighborhood Hits	166	Shared Neighborhood Hits	16
SwissProt Accessions	P00739, Q7LE20, Q92658, Q92659, Q9ULB0	Gene names	HPR
Domain Architecture
Description	Haptoglobin-related protein precursor.

PCOC1_MOUSE
NC score	0.051834 (rank : 450)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	127	Target Neighborhood Hits	100	Shared Neighborhood Hits	16
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

KLK5_HUMAN
NC score	0.051744 (rank : 451)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	127	Target Neighborhood Hits	182	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y337, Q9HBG8	Gene names	KLK5, SCTE
Domain Architecture
Description	Kallikrein-5 precursor (EC 3.4.21.-) (Stratum corneum tryptic enzyme) (Kallikrein-like protein 2) (KLK-L2).

CFAD_MOUSE
NC score	0.051674 (rank : 452)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	127	Target Neighborhood Hits	177	Shared Neighborhood Hits	16
SwissProt Accessions	P03953, Q61280	Gene names	Cfd, Adn, Df
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin) (28 kDa adipocyte protein).

SFTPD_MOUSE
NC score	0.051624 (rank : 453)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	127	Target Neighborhood Hits	217	Shared Neighborhood Hits	28
SwissProt Accessions	P50404	Gene names	Sftpd, Sftp4
Domain Architecture
Description	Pulmonary surfactant-associated protein D precursor (SP-D) (PSP-D).

KLK13_HUMAN
NC score	0.051498 (rank : 454)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	127	Target Neighborhood Hits	179	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UKR3, Q9Y433	Gene names	KLK13, KLKL4
Domain Architecture
Description	Kallikrein-13 precursor (EC 3.4.21.-) (Kallikrein-like protein 4) (KLK-L4).

KLK4_HUMAN
NC score	0.051369 (rank : 455)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	127	Target Neighborhood Hits	175	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y5K2, Q4VB16, Q9GZL6, Q9UBJ6	Gene names	KLK4, EMSP1, PRSS17, PSTS
Domain Architecture
Description	Kallikrein-4 precursor (EC 3.4.21.-) (Prostase) (Kallikrein-like protein 1) (KLK-L1) (Enamel matrix serine proteinase 1).

HGFL_HUMAN
NC score	0.051278 (rank : 456)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	127	Target Neighborhood Hits	190	Shared Neighborhood Hits	16
SwissProt Accessions	P26927, Q13350, Q14870	Gene names	MST1, HGFL
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) (Macrophage-stimulating protein) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

HGFL_MOUSE
NC score	0.051248 (rank : 457)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	127	Target Neighborhood Hits	188	Shared Neighborhood Hits	16
SwissProt Accessions	P26928	Gene names	Mst1, Hgfl
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

KLK6_HUMAN
NC score	0.051203 (rank : 458)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	127	Target Neighborhood Hits	175	Shared Neighborhood Hits	16
SwissProt Accessions	Q92876	Gene names	KLK6, PRSS18, PRSS9
Domain Architecture
Description	Kallikrein-6 precursor (EC 3.4.21.-) (Protease M) (Neurosin) (Zyme) (SP59).

KLK14_HUMAN
NC score	0.051201 (rank : 459)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	127	Target Neighborhood Hits	179	Shared Neighborhood Hits	16
SwissProt Accessions	Q9P0G3	Gene names	KLK14, KLKL6
Domain Architecture
Description	Kallikrein-14 precursor (EC 3.4.21.-) (Kallikrein-like protein 6) (KLK-L6).

KLK15_HUMAN
NC score	0.051181 (rank : 460)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	127	Target Neighborhood Hits	180	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H2R5, Q15358, Q9H2R3, Q9H2R4, Q9H2R6, Q9HBG9	Gene names	KLK15
Domain Architecture
Description	Kallikrein-15 precursor (EC 3.4.21.-) (ACO protease).

KR109_HUMAN
NC score	0.051168 (rank : 461)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	127	Target Neighborhood Hits	226	Shared Neighborhood Hits	25
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

TECTA_HUMAN
NC score	0.051000 (rank : 462)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	127	Target Neighborhood Hits	239	Shared Neighborhood Hits	29
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

NRPN_HUMAN
NC score	0.050660 (rank : 463)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	127	Target Neighborhood Hits	182	Shared Neighborhood Hits	16
SwissProt Accessions	O60259, Q9HCB3, Q9UIL9, Q9UQ47	Gene names	KLK8, NRPN, PRSS19, TADG14
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8) (Ovasin) (Serine protease TADG-14) (Tumor-associated differentially expressed gene 14 protein).

KLK7_MOUSE
NC score	0.050646 (rank : 464)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	127	Target Neighborhood Hits	175	Shared Neighborhood Hits	16
SwissProt Accessions	Q91VE3, Q9R048	Gene names	Klk7, Prss6, Scce
Domain Architecture	No domain graphic available
Description	Kallikrein-7 precursor (EC 3.4.21.-) (Stratum corneum chymotryptic enzyme) (Thymopsin).

NTNG2_HUMAN
NC score	0.050442 (rank : 465)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	127	Target Neighborhood Hits	276	Shared Neighborhood Hits	27
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

ELTD1_MOUSE
NC score	0.050438 (rank : 466)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	127	Target Neighborhood Hits	288	Shared Neighborhood Hits	25
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

CLC11_HUMAN
NC score	0.050386 (rank : 467)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	127	Target Neighborhood Hits	57	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y240	Gene names	CLEC11A, CLECSF3, LSLCL, SCGF
Domain Architecture
Description	C-type lectin domain family 11 member A precursor (Stem cell growth factor) (Lymphocyte secreted C-type lectin) (p47) (C-type lectin superfamily member 3).

CO2_HUMAN
NC score	0.050371 (rank : 468)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	127	Target Neighborhood Hits	258	Shared Neighborhood Hits	21
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

MEGF9_HUMAN
NC score	0.050362 (rank : 469)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	127	Target Neighborhood Hits	557	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

CLC14_HUMAN
NC score	0.050219 (rank : 470)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	127	Target Neighborhood Hits	143	Shared Neighborhood Hits	22
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

LAMA3_MOUSE
NC score	0.050161 (rank : 471)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	127	Target Neighborhood Hits	859	Shared Neighborhood Hits	39
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

VTDB_HUMAN
NC score	0.040346 (rank : 472)	θ value	1.38821 (rank : 87)
Query Neighborhood Hits	127	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P02774, Q16309, Q16310	Gene names	GC
Domain Architecture
Description	Vitamin D-binding protein precursor (DBP) (Group-specific component) (Gc-globulin) (VDB).

IRX4_MOUSE
NC score	0.026448 (rank : 473)	θ value	0.21417 (rank : 66)
Query Neighborhood Hits	127	Target Neighborhood Hits	286	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QY61	Gene names	Irx4, Irxa3
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-4 (Iroquois homeobox protein 4) (Homeodomain protein IRXA3).

RUNX3_MOUSE
NC score	0.024462 (rank : 474)	θ value	1.38821 (rank : 85)
Query Neighborhood Hits	127	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	Q64131, Q99P92, Q9R199	Gene names	Runx3, Aml2, Cbfa3, Pebp2a3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

CO1A1_MOUSE
NC score	0.019243 (rank : 475)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	127	Target Neighborhood Hits	457	Shared Neighborhood Hits	16
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

RUNX3_HUMAN
NC score	0.017903 (rank : 476)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	127	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	Q13761, Q12969, Q13760	Gene names	RUNX3, AML2, CBFA3, PEBP2A3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

OSBL3_HUMAN
NC score	0.010940 (rank : 477)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	127	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

MAP4_MOUSE
NC score	0.010739 (rank : 478)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	127	Target Neighborhood Hits	409	Shared Neighborhood Hits	7
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MGR6_MOUSE
NC score	0.010038 (rank : 479)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	127	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	Q5NCH9	Gene names	Grm6, Gprc1f, Mglur6
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

MGR6_HUMAN
NC score	0.009454 (rank : 480)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	127	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	O15303	Gene names	GRM6, GPRC1F, MGLUR6
Domain Architecture
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

MAGE1_HUMAN
NC score	0.007963 (rank : 481)	θ value	2.36792 (rank : 96)
Query Neighborhood Hits	127	Target Neighborhood Hits	1389	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

BIN1_MOUSE
NC score	0.007408 (rank : 482)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	127	Target Neighborhood Hits	283	Shared Neighborhood Hits	4
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

TRI34_MOUSE
NC score	0.006336 (rank : 483)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	127	Target Neighborhood Hits	332	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

CAC1F_HUMAN
NC score	0.002934 (rank : 484)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	127	Target Neighborhood Hits	141	Shared Neighborhood Hits	3
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

EGR4_HUMAN
NC score	-0.001193 (rank : 485)	θ value	1.81305 (rank : 90)
Query Neighborhood Hits	127	Target Neighborhood Hits	939	Shared Neighborhood Hits	4
SwissProt Accessions	Q05215	Gene names	EGR4
Domain Architecture
Description	Early growth response protein 4 (EGR-4) (AT133).