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Network neighborhood for query Sequence : EGFL8_HUMAN

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EGFL8_HUMAN
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EGFL8_HUMAN
θ value	9.49765e-159 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	270	Target Neighborhood Hits	270	Shared Neighborhood Hits	270
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL8_MOUSE
θ value	1.2462e-142 (rank : 2)	NC score	0.985413 (rank : 2)
Query Neighborhood Hits	270	Target Neighborhood Hits	266	Shared Neighborhood Hits	240
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EGFL7_HUMAN
θ value	2.05049e-36 (rank : 3)	NC score	0.909491 (rank : 3)
Query Neighborhood Hits	270	Target Neighborhood Hits	325	Shared Neighborhood Hits	228
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL7_MOUSE
θ value	6.59618e-35 (rank : 4)	NC score	0.905990 (rank : 4)
Query Neighborhood Hits	270	Target Neighborhood Hits	287	Shared Neighborhood Hits	223
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

FBN2_MOUSE
θ value	7.84624e-12 (rank : 5)	NC score	0.746715 (rank : 16)
Query Neighborhood Hits	270	Target Neighborhood Hits	549	Shared Neighborhood Hits	249
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_HUMAN
θ value	1.74796e-11 (rank : 6)	NC score	0.744034 (rank : 17)
Query Neighborhood Hits	270	Target Neighborhood Hits	560	Shared Neighborhood Hits	249
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

NELL1_HUMAN
θ value	2.98157e-11 (rank : 7)	NC score	0.734095 (rank : 36)
Query Neighborhood Hits	270	Target Neighborhood Hits	451	Shared Neighborhood Hits	232
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NOTC3_MOUSE
θ value	6.64225e-11 (rank : 8)	NC score	0.671310 (rank : 66)
Query Neighborhood Hits	270	Target Neighborhood Hits	975	Shared Neighborhood Hits	255
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

FBN3_HUMAN
θ value	2.52405e-10 (rank : 9)	NC score	0.748281 (rank : 14)
Query Neighborhood Hits	270	Target Neighborhood Hits	543	Shared Neighborhood Hits	248
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

NOTC2_MOUSE
θ value	4.30538e-10 (rank : 10)	NC score	0.671879 (rank : 64)
Query Neighborhood Hits	270	Target Neighborhood Hits	1069	Shared Neighborhood Hits	254
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC4_HUMAN
θ value	5.62301e-10 (rank : 11)	NC score	0.656051 (rank : 75)
Query Neighborhood Hits	270	Target Neighborhood Hits	905	Shared Neighborhood Hits	252
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

JAG2_MOUSE
θ value	9.59137e-10 (rank : 12)	NC score	0.742597 (rank : 22)
Query Neighborhood Hits	270	Target Neighborhood Hits	504	Shared Neighborhood Hits	242
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

PROZ_MOUSE
θ value	1.63604e-09 (rank : 13)	NC score	0.635025 (rank : 83)
Query Neighborhood Hits	270	Target Neighborhood Hits	410	Shared Neighborhood Hits	218
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

JAG2_HUMAN
θ value	2.13673e-09 (rank : 14)	NC score	0.742334 (rank : 24)
Query Neighborhood Hits	270	Target Neighborhood Hits	491	Shared Neighborhood Hits	244
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG1_HUMAN
θ value	2.79066e-09 (rank : 15)	NC score	0.736568 (rank : 33)
Query Neighborhood Hits	270	Target Neighborhood Hits	514	Shared Neighborhood Hits	244
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

NOTC1_MOUSE
θ value	2.79066e-09 (rank : 16)	NC score	0.688288 (rank : 62)
Query Neighborhood Hits	270	Target Neighborhood Hits	916	Shared Neighborhood Hits	253
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC3_HUMAN
θ value	3.64472e-09 (rank : 17)	NC score	0.669831 (rank : 67)
Query Neighborhood Hits	270	Target Neighborhood Hits	1062	Shared Neighborhood Hits	252
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

MEGF6_HUMAN
θ value	4.76016e-09 (rank : 18)	NC score	0.710658 (rank : 59)
Query Neighborhood Hits	270	Target Neighborhood Hits	671	Shared Neighborhood Hits	256
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

NELL2_HUMAN
θ value	4.76016e-09 (rank : 19)	NC score	0.742249 (rank : 25)
Query Neighborhood Hits	270	Target Neighborhood Hits	449	Shared Neighborhood Hits	239
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
θ value	4.76016e-09 (rank : 20)	NC score	0.742802 (rank : 21)
Query Neighborhood Hits	270	Target Neighborhood Hits	436	Shared Neighborhood Hits	240
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NOTC2_HUMAN
θ value	4.76016e-09 (rank : 21)	NC score	0.668473 (rank : 68)
Query Neighborhood Hits	270	Target Neighborhood Hits	1113	Shared Neighborhood Hits	254
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

CRUM1_HUMAN
θ value	6.21693e-09 (rank : 22)	NC score	0.736655 (rank : 31)
Query Neighborhood Hits	270	Target Neighborhood Hits	457	Shared Neighborhood Hits	239
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

DLL1_MOUSE
θ value	8.11959e-09 (rank : 23)	NC score	0.738480 (rank : 29)
Query Neighborhood Hits	270	Target Neighborhood Hits	456	Shared Neighborhood Hits	243
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

PROZ_HUMAN
θ value	8.11959e-09 (rank : 24)	NC score	0.625810 (rank : 85)
Query Neighborhood Hits	270	Target Neighborhood Hits	422	Shared Neighborhood Hits	224
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

FBN1_HUMAN
θ value	1.06045e-08 (rank : 25)	NC score	0.742386 (rank : 23)
Query Neighborhood Hits	270	Target Neighborhood Hits	557	Shared Neighborhood Hits	250
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

GAS6_MOUSE
θ value	1.38499e-08 (rank : 26)	NC score	0.761455 (rank : 6)
Query Neighborhood Hits	270	Target Neighborhood Hits	343	Shared Neighborhood Hits	230
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

FBN1_MOUSE
θ value	3.08544e-08 (rank : 27)	NC score	0.741690 (rank : 26)
Query Neighborhood Hits	270	Target Neighborhood Hits	563	Shared Neighborhood Hits	254
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

GAS6_HUMAN
θ value	3.08544e-08 (rank : 28)	NC score	0.763043 (rank : 5)
Query Neighborhood Hits	270	Target Neighborhood Hits	348	Shared Neighborhood Hits	227
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

CRUM1_MOUSE
θ value	4.0297e-08 (rank : 29)	NC score	0.737550 (rank : 30)
Query Neighborhood Hits	270	Target Neighborhood Hits	444	Shared Neighborhood Hits	240
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

FATH_HUMAN
θ value	4.0297e-08 (rank : 30)	NC score	0.394860 (rank : 153)
Query Neighborhood Hits	270	Target Neighborhood Hits	570	Shared Neighborhood Hits	222
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

JAG1_MOUSE
θ value	4.0297e-08 (rank : 31)	NC score	0.735496 (rank : 34)
Query Neighborhood Hits	270	Target Neighborhood Hits	518	Shared Neighborhood Hits	243
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

LTB1L_MOUSE
θ value	4.0297e-08 (rank : 32)	NC score	0.729639 (rank : 43)
Query Neighborhood Hits	270	Target Neighborhood Hits	514	Shared Neighborhood Hits	249
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

FBLN1_HUMAN
θ value	5.26297e-08 (rank : 33)	NC score	0.747899 (rank : 15)
Query Neighborhood Hits	270	Target Neighborhood Hits	324	Shared Neighborhood Hits	209
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

LTB1L_HUMAN
θ value	5.26297e-08 (rank : 34)	NC score	0.725144 (rank : 47)
Query Neighborhood Hits	270	Target Neighborhood Hits	553	Shared Neighborhood Hits	245
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

NOTC4_MOUSE
θ value	5.26297e-08 (rank : 35)	NC score	0.654741 (rank : 76)
Query Neighborhood Hits	270	Target Neighborhood Hits	872	Shared Neighborhood Hits	252
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

FBLN5_MOUSE
θ value	6.87365e-08 (rank : 36)	NC score	0.751073 (rank : 11)
Query Neighborhood Hits	270	Target Neighborhood Hits	317	Shared Neighborhood Hits	209
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBLN1_MOUSE
θ value	8.97725e-08 (rank : 37)	NC score	0.743403 (rank : 18)
Query Neighborhood Hits	270	Target Neighborhood Hits	329	Shared Neighborhood Hits	209
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

CRUM2_HUMAN
θ value	1.17247e-07 (rank : 38)	NC score	0.748691 (rank : 13)
Query Neighborhood Hits	270	Target Neighborhood Hits	453	Shared Neighborhood Hits	243
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

DLL1_HUMAN
θ value	1.53129e-07 (rank : 39)	NC score	0.734832 (rank : 35)
Query Neighborhood Hits	270	Target Neighborhood Hits	455	Shared Neighborhood Hits	240
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

FBLN5_HUMAN
θ value	1.53129e-07 (rank : 40)	NC score	0.751655 (rank : 10)
Query Neighborhood Hits	270	Target Neighborhood Hits	329	Shared Neighborhood Hits	211
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

NOTC1_HUMAN
θ value	1.53129e-07 (rank : 41)	NC score	0.666952 (rank : 69)
Query Neighborhood Hits	270	Target Neighborhood Hits	906	Shared Neighborhood Hits	249
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

C1QR1_HUMAN
θ value	1.99992e-07 (rank : 42)	NC score	0.758061 (rank : 8)
Query Neighborhood Hits	270	Target Neighborhood Hits	493	Shared Neighborhood Hits	227
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

DNER_MOUSE
θ value	2.61198e-07 (rank : 43)	NC score	0.732369 (rank : 40)
Query Neighborhood Hits	270	Target Neighborhood Hits	413	Shared Neighborhood Hits	226
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

C1QR1_MOUSE
θ value	4.45536e-07 (rank : 44)	NC score	0.761334 (rank : 7)
Query Neighborhood Hits	270	Target Neighborhood Hits	342	Shared Neighborhood Hits	217
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

SLIT1_MOUSE
θ value	4.45536e-07 (rank : 45)	NC score	0.536897 (rank : 116)
Query Neighborhood Hits	270	Target Neighborhood Hits	715	Shared Neighborhood Hits	229
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

DLK_MOUSE
θ value	7.59969e-07 (rank : 46)	NC score	0.726314 (rank : 46)
Query Neighborhood Hits	270	Target Neighborhood Hits	374	Shared Neighborhood Hits	222
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

PROS_HUMAN
θ value	7.59969e-07 (rank : 47)	NC score	0.754674 (rank : 9)
Query Neighborhood Hits	270	Target Neighborhood Hits	340	Shared Neighborhood Hits	226
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

DLL4_MOUSE
θ value	9.92553e-07 (rank : 48)	NC score	0.719508 (rank : 51)
Query Neighborhood Hits	270	Target Neighborhood Hits	440	Shared Neighborhood Hits	226
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

FA10_MOUSE
θ value	9.92553e-07 (rank : 49)	NC score	0.374410 (rank : 161)
Query Neighborhood Hits	270	Target Neighborhood Hits	435	Shared Neighborhood Hits	221
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

SLIT2_HUMAN
θ value	9.92553e-07 (rank : 50)	NC score	0.523237 (rank : 119)
Query Neighborhood Hits	270	Target Neighborhood Hits	708	Shared Neighborhood Hits	228
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT2_MOUSE
θ value	9.92553e-07 (rank : 51)	NC score	0.521080 (rank : 120)
Query Neighborhood Hits	270	Target Neighborhood Hits	684	Shared Neighborhood Hits	223
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

CSPG2_MOUSE
θ value	1.69304e-06 (rank : 52)	NC score	0.501919 (rank : 130)
Query Neighborhood Hits	270	Target Neighborhood Hits	711	Shared Neighborhood Hits	198
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

FBLN2_MOUSE
θ value	1.69304e-06 (rank : 53)	NC score	0.736601 (rank : 32)
Query Neighborhood Hits	270	Target Neighborhood Hits	505	Shared Neighborhood Hits	220
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_HUMAN
θ value	2.21117e-06 (rank : 54)	NC score	0.742857 (rank : 20)
Query Neighborhood Hits	270	Target Neighborhood Hits	392	Shared Neighborhood Hits	208
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

MATN2_HUMAN
θ value	2.88788e-06 (rank : 55)	NC score	0.671831 (rank : 65)
Query Neighborhood Hits	270	Target Neighborhood Hits	365	Shared Neighborhood Hits	200
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

FA9_HUMAN
θ value	3.77169e-06 (rank : 56)	NC score	0.353551 (rank : 172)
Query Neighborhood Hits	270	Target Neighborhood Hits	421	Shared Neighborhood Hits	206
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

DNER_HUMAN
θ value	4.92598e-06 (rank : 57)	NC score	0.729410 (rank : 44)
Query Neighborhood Hits	270	Target Neighborhood Hits	460	Shared Neighborhood Hits	228
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

LRP2_HUMAN
θ value	4.92598e-06 (rank : 58)	NC score	0.546631 (rank : 113)
Query Neighborhood Hits	270	Target Neighborhood Hits	573	Shared Neighborhood Hits	245
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

PROS_MOUSE
θ value	4.92598e-06 (rank : 59)	NC score	0.750407 (rank : 12)
Query Neighborhood Hits	270	Target Neighborhood Hits	330	Shared Neighborhood Hits	223
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

WIF1_HUMAN
θ value	4.92598e-06 (rank : 60)	NC score	0.658261 (rank : 73)
Query Neighborhood Hits	270	Target Neighborhood Hits	392	Shared Neighborhood Hits	213
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_MOUSE
θ value	4.92598e-06 (rank : 61)	NC score	0.650435 (rank : 82)
Query Neighborhood Hits	270	Target Neighborhood Hits	393	Shared Neighborhood Hits	207
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

CSPG2_HUMAN
θ value	6.43352e-06 (rank : 62)	NC score	0.495846 (rank : 136)
Query Neighborhood Hits	270	Target Neighborhood Hits	681	Shared Neighborhood Hits	196
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CUBN_HUMAN
θ value	6.43352e-06 (rank : 63)	NC score	0.652842 (rank : 79)
Query Neighborhood Hits	270	Target Neighborhood Hits	482	Shared Neighborhood Hits	240
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

EGFL9_MOUSE
θ value	6.43352e-06 (rank : 64)	NC score	0.733643 (rank : 37)
Query Neighborhood Hits	270	Target Neighborhood Hits	379	Shared Neighborhood Hits	226
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

FBLN4_HUMAN
θ value	6.43352e-06 (rank : 65)	NC score	0.743177 (rank : 19)
Query Neighborhood Hits	270	Target Neighborhood Hits	278	Shared Neighborhood Hits	204
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	6.43352e-06 (rank : 66)	NC score	0.738716 (rank : 28)
Query Neighborhood Hits	270	Target Neighborhood Hits	270	Shared Neighborhood Hits	202
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

DLL3_MOUSE
θ value	1.09739e-05 (rank : 67)	NC score	0.723453 (rank : 48)
Query Neighborhood Hits	270	Target Neighborhood Hits	399	Shared Neighborhood Hits	223
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

EGFL9_HUMAN
θ value	1.09739e-05 (rank : 68)	NC score	0.729153 (rank : 45)
Query Neighborhood Hits	270	Target Neighborhood Hits	365	Shared Neighborhood Hits	225
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

FBLN3_HUMAN
θ value	1.09739e-05 (rank : 69)	NC score	0.732986 (rank : 39)
Query Neighborhood Hits	270	Target Neighborhood Hits	293	Shared Neighborhood Hits	205
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN3_MOUSE
θ value	1.09739e-05 (rank : 70)	NC score	0.730280 (rank : 42)
Query Neighborhood Hits	270	Target Neighborhood Hits	279	Shared Neighborhood Hits	200
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

DLL3_HUMAN
θ value	1.43324e-05 (rank : 71)	NC score	0.717749 (rank : 56)
Query Neighborhood Hits	270	Target Neighborhood Hits	419	Shared Neighborhood Hits	221
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

LTBP4_MOUSE
θ value	1.87187e-05 (rank : 72)	NC score	0.741079 (rank : 27)
Query Neighborhood Hits	270	Target Neighborhood Hits	607	Shared Neighborhood Hits	243
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

LTBP2_HUMAN
θ value	2.44474e-05 (rank : 73)	NC score	0.718301 (rank : 53)
Query Neighborhood Hits	270	Target Neighborhood Hits	552	Shared Neighborhood Hits	246
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

SCUB3_MOUSE
θ value	2.44474e-05 (rank : 74)	NC score	0.717684 (rank : 57)
Query Neighborhood Hits	270	Target Neighborhood Hits	442	Shared Neighborhood Hits	217
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SLIT1_HUMAN
θ value	2.44474e-05 (rank : 75)	NC score	0.532228 (rank : 117)
Query Neighborhood Hits	270	Target Neighborhood Hits	700	Shared Neighborhood Hits	230
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

DLL4_HUMAN
θ value	3.19293e-05 (rank : 76)	NC score	0.719524 (rank : 50)
Query Neighborhood Hits	270	Target Neighborhood Hits	435	Shared Neighborhood Hits	227
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

HMCN1_HUMAN
θ value	3.19293e-05 (rank : 77)	NC score	0.433620 (rank : 146)
Query Neighborhood Hits	270	Target Neighborhood Hits	983	Shared Neighborhood Hits	216
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

LTBP3_MOUSE
θ value	3.19293e-05 (rank : 78)	NC score	0.733537 (rank : 38)
Query Neighborhood Hits	270	Target Neighborhood Hits	475	Shared Neighborhood Hits	242
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

NID1_HUMAN
θ value	3.19293e-05 (rank : 79)	NC score	0.653997 (rank : 78)
Query Neighborhood Hits	270	Target Neighborhood Hits	329	Shared Neighborhood Hits	205
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

EGF_MOUSE
θ value	4.1701e-05 (rank : 80)	NC score	0.680367 (rank : 63)
Query Neighborhood Hits	270	Target Neighborhood Hits	358	Shared Neighborhood Hits	233
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

LTBP3_HUMAN
θ value	4.1701e-05 (rank : 81)	NC score	0.730947 (rank : 41)
Query Neighborhood Hits	270	Target Neighborhood Hits	502	Shared Neighborhood Hits	240
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

PROC_HUMAN
θ value	4.1701e-05 (rank : 82)	NC score	0.326302 (rank : 196)
Query Neighborhood Hits	270	Target Neighborhood Hits	406	Shared Neighborhood Hits	210
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

SCUB3_HUMAN
θ value	4.1701e-05 (rank : 83)	NC score	0.717482 (rank : 58)
Query Neighborhood Hits	270	Target Neighborhood Hits	428	Shared Neighborhood Hits	212
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SLIT3_HUMAN
θ value	4.1701e-05 (rank : 84)	NC score	0.507973 (rank : 124)
Query Neighborhood Hits	270	Target Neighborhood Hits	682	Shared Neighborhood Hits	226
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

DLK_HUMAN
θ value	5.44631e-05 (rank : 85)	NC score	0.717904 (rank : 55)
Query Neighborhood Hits	270	Target Neighborhood Hits	401	Shared Neighborhood Hits	223
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

LRP1_HUMAN
θ value	5.44631e-05 (rank : 86)	NC score	0.583691 (rank : 101)
Query Neighborhood Hits	270	Target Neighborhood Hits	617	Shared Neighborhood Hits	255
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

PROC_MOUSE
θ value	5.44631e-05 (rank : 87)	NC score	0.348577 (rank : 177)
Query Neighborhood Hits	270	Target Neighborhood Hits	426	Shared Neighborhood Hits	213
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

MATN4_HUMAN
θ value	9.29e-05 (rank : 88)	NC score	0.603380 (rank : 90)
Query Neighborhood Hits	270	Target Neighborhood Hits	287	Shared Neighborhood Hits	190
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MEGF8_MOUSE
θ value	9.29e-05 (rank : 89)	NC score	0.557146 (rank : 110)
Query Neighborhood Hits	270	Target Neighborhood Hits	520	Shared Neighborhood Hits	228
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

NID2_MOUSE
θ value	9.29e-05 (rank : 90)	NC score	0.664973 (rank : 70)
Query Neighborhood Hits	270	Target Neighborhood Hits	338	Shared Neighborhood Hits	211
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

LRP4_MOUSE
θ value	0.000121331 (rank : 91)	NC score	0.506277 (rank : 126)
Query Neighborhood Hits	270	Target Neighborhood Hits	351	Shared Neighborhood Hits	202
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LTB1S_MOUSE
θ value	0.000121331 (rank : 92)	NC score	0.721995 (rank : 49)
Query Neighborhood Hits	270	Target Neighborhood Hits	479	Shared Neighborhood Hits	245
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP2_MOUSE
θ value	0.000121331 (rank : 93)	NC score	0.719233 (rank : 52)
Query Neighborhood Hits	270	Target Neighborhood Hits	617	Shared Neighborhood Hits	243
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTB1S_HUMAN
θ value	0.000158464 (rank : 94)	NC score	0.718260 (rank : 54)
Query Neighborhood Hits	270	Target Neighborhood Hits	502	Shared Neighborhood Hits	244
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

EGF_HUMAN
θ value	0.00020696 (rank : 95)	NC score	0.656661 (rank : 74)
Query Neighborhood Hits	270	Target Neighborhood Hits	343	Shared Neighborhood Hits	221
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

CSPG3_HUMAN
θ value	0.000270298 (rank : 96)	NC score	0.470346 (rank : 141)
Query Neighborhood Hits	270	Target Neighborhood Hits	676	Shared Neighborhood Hits	187
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CSPG3_MOUSE
θ value	0.000270298 (rank : 97)	NC score	0.476574 (rank : 138)
Query Neighborhood Hits	270	Target Neighborhood Hits	657	Shared Neighborhood Hits	193
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CUBN_MOUSE
θ value	0.000270298 (rank : 98)	NC score	0.652820 (rank : 80)
Query Neighborhood Hits	270	Target Neighborhood Hits	477	Shared Neighborhood Hits	247
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

MEGF8_HUMAN
θ value	0.000270298 (rank : 99)	NC score	0.554390 (rank : 111)
Query Neighborhood Hits	270	Target Neighborhood Hits	528	Shared Neighborhood Hits	224
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

NID1_MOUSE
θ value	0.000270298 (rank : 100)	NC score	0.652163 (rank : 81)
Query Neighborhood Hits	270	Target Neighborhood Hits	335	Shared Neighborhood Hits	202
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

SREC2_HUMAN
θ value	0.000270298 (rank : 101)	NC score	0.547435 (rank : 112)
Query Neighborhood Hits	270	Target Neighborhood Hits	645	Shared Neighborhood Hits	208
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

EDIL3_HUMAN
θ value	0.00035302 (rank : 102)	NC score	0.567021 (rank : 105)
Query Neighborhood Hits	270	Target Neighborhood Hits	292	Shared Neighborhood Hits	196
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

FA10_HUMAN
θ value	0.00035302 (rank : 103)	NC score	0.362974 (rank : 167)
Query Neighborhood Hits	270	Target Neighborhood Hits	431	Shared Neighborhood Hits	210
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FAT2_HUMAN
θ value	0.00035302 (rank : 104)	NC score	0.254583 (rank : 275)
Query Neighborhood Hits	270	Target Neighborhood Hits	507	Shared Neighborhood Hits	165
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

LRP1B_HUMAN
θ value	0.00035302 (rank : 105)	NC score	0.586528 (rank : 100)
Query Neighborhood Hits	270	Target Neighborhood Hits	602	Shared Neighborhood Hits	255
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

MATN2_MOUSE
θ value	0.00035302 (rank : 106)	NC score	0.663267 (rank : 71)
Query Neighborhood Hits	270	Target Neighborhood Hits	356	Shared Neighborhood Hits	200
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

LRP1B_MOUSE
θ value	0.000461057 (rank : 107)	NC score	0.586686 (rank : 99)
Query Neighborhood Hits	270	Target Neighborhood Hits	606	Shared Neighborhood Hits	254
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

EDIL3_MOUSE
θ value	0.000602161 (rank : 108)	NC score	0.564915 (rank : 106)
Query Neighborhood Hits	270	Target Neighborhood Hits	317	Shared Neighborhood Hits	201
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

SLIT3_MOUSE
θ value	0.000602161 (rank : 109)	NC score	0.505674 (rank : 128)
Query Neighborhood Hits	270	Target Neighborhood Hits	700	Shared Neighborhood Hits	225
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

SREC_HUMAN
θ value	0.000602161 (rank : 110)	NC score	0.563028 (rank : 108)
Query Neighborhood Hits	270	Target Neighborhood Hits	645	Shared Neighborhood Hits	213
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

LRP4_HUMAN
θ value	0.000786445 (rank : 111)	NC score	0.500708 (rank : 132)
Query Neighborhood Hits	270	Target Neighborhood Hits	355	Shared Neighborhood Hits	206
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

NID2_HUMAN
θ value	0.000786445 (rank : 112)	NC score	0.659651 (rank : 72)
Query Neighborhood Hits	270	Target Neighborhood Hits	456	Shared Neighborhood Hits	215
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

STAB1_HUMAN
θ value	0.000786445 (rank : 113)	NC score	0.595348 (rank : 94)
Query Neighborhood Hits	270	Target Neighborhood Hits	546	Shared Neighborhood Hits	228
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

TLL1_MOUSE
θ value	0.000786445 (rank : 114)	NC score	0.346228 (rank : 180)
Query Neighborhood Hits	270	Target Neighborhood Hits	237	Shared Neighborhood Hits	157
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

CREL1_MOUSE
θ value	0.00102713 (rank : 115)	NC score	0.606221 (rank : 89)
Query Neighborhood Hits	270	Target Neighborhood Hits	524	Shared Neighborhood Hits	200
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

EMR2_HUMAN
θ value	0.00102713 (rank : 116)	NC score	0.592338 (rank : 96)
Query Neighborhood Hits	270	Target Neighborhood Hits	345	Shared Neighborhood Hits	202
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

MASP1_HUMAN
θ value	0.00102713 (rank : 117)	NC score	0.209852 (rank : 315)
Query Neighborhood Hits	270	Target Neighborhood Hits	369	Shared Neighborhood Hits	138
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

MASP1_MOUSE
θ value	0.00102713 (rank : 118)	NC score	0.206413 (rank : 318)
Query Neighborhood Hits	270	Target Neighborhood Hits	364	Shared Neighborhood Hits	139
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

HHIP_HUMAN
θ value	0.00134147 (rank : 119)	NC score	0.500343 (rank : 133)
Query Neighborhood Hits	270	Target Neighborhood Hits	249	Shared Neighborhood Hits	142
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

LAMC1_MOUSE
θ value	0.00134147 (rank : 120)	NC score	0.318471 (rank : 209)
Query Neighborhood Hits	270	Target Neighborhood Hits	856	Shared Neighborhood Hits	181
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

SREC2_MOUSE
θ value	0.00134147 (rank : 121)	NC score	0.559909 (rank : 109)
Query Neighborhood Hits	270	Target Neighborhood Hits	605	Shared Neighborhood Hits	211
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

TRBM_MOUSE
θ value	0.00134147 (rank : 122)	NC score	0.706625 (rank : 61)
Query Neighborhood Hits	270	Target Neighborhood Hits	361	Shared Neighborhood Hits	213
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

CD97_HUMAN
θ value	0.00175202 (rank : 123)	NC score	0.581568 (rank : 103)
Query Neighborhood Hits	270	Target Neighborhood Hits	353	Shared Neighborhood Hits	201
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

HHIP_MOUSE
θ value	0.00228821 (rank : 124)	NC score	0.498803 (rank : 134)
Query Neighborhood Hits	270	Target Neighborhood Hits	219	Shared Neighborhood Hits	138
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

STAB1_MOUSE
θ value	0.00228821 (rank : 125)	NC score	0.591279 (rank : 97)
Query Neighborhood Hits	270	Target Neighborhood Hits	566	Shared Neighborhood Hits	233
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

CELR3_HUMAN
θ value	0.00390308 (rank : 126)	NC score	0.318757 (rank : 208)
Query Neighborhood Hits	270	Target Neighborhood Hits	680	Shared Neighborhood Hits	215
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CD248_HUMAN
θ value	0.00509761 (rank : 127)	NC score	0.606582 (rank : 88)
Query Neighborhood Hits	270	Target Neighborhood Hits	679	Shared Neighborhood Hits	197
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

MASP2_HUMAN
θ value	0.00509761 (rank : 128)	NC score	0.214495 (rank : 310)
Query Neighborhood Hits	270	Target Neighborhood Hits	364	Shared Neighborhood Hits	138
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

TLL1_HUMAN
θ value	0.00509761 (rank : 129)	NC score	0.341127 (rank : 183)
Query Neighborhood Hits	270	Target Neighborhood Hits	236	Shared Neighborhood Hits	156
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

CD248_MOUSE
θ value	0.00665767 (rank : 130)	NC score	0.620763 (rank : 87)
Query Neighborhood Hits	270	Target Neighborhood Hits	578	Shared Neighborhood Hits	194
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

MATN3_MOUSE
θ value	0.00665767 (rank : 131)	NC score	0.596653 (rank : 92)
Query Neighborhood Hits	270	Target Neighborhood Hits	261	Shared Neighborhood Hits	181
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

PERT_MOUSE
θ value	0.00665767 (rank : 132)	NC score	0.327133 (rank : 194)
Query Neighborhood Hits	270	Target Neighborhood Hits	221	Shared Neighborhood Hits	145
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

CELR1_MOUSE
θ value	0.00869519 (rank : 133)	NC score	0.313625 (rank : 215)
Query Neighborhood Hits	270	Target Neighborhood Hits	617	Shared Neighborhood Hits	218
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

TLL2_HUMAN
θ value	0.00869519 (rank : 134)	NC score	0.337324 (rank : 188)
Query Neighborhood Hits	270	Target Neighborhood Hits	241	Shared Neighborhood Hits	156
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

CELR1_HUMAN
θ value	0.0113563 (rank : 135)	NC score	0.308463 (rank : 222)
Query Neighborhood Hits	270	Target Neighborhood Hits	613	Shared Neighborhood Hits	218
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CS1B_MOUSE
θ value	0.0113563 (rank : 136)	NC score	0.215013 (rank : 308)
Query Neighborhood Hits	270	Target Neighborhood Hits	361	Shared Neighborhood Hits	135
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

HGFA_HUMAN
θ value	0.0113563 (rank : 137)	NC score	0.275921 (rank : 265)
Query Neighborhood Hits	270	Target Neighborhood Hits	436	Shared Neighborhood Hits	179
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

LRP6_HUMAN
θ value	0.0113563 (rank : 138)	NC score	0.309820 (rank : 219)
Query Neighborhood Hits	270	Target Neighborhood Hits	235	Shared Neighborhood Hits	130
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
θ value	0.0113563 (rank : 139)	NC score	0.306559 (rank : 224)
Query Neighborhood Hits	270	Target Neighborhood Hits	232	Shared Neighborhood Hits	129
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

MASP2_MOUSE
θ value	0.0113563 (rank : 140)	NC score	0.210063 (rank : 314)
Query Neighborhood Hits	270	Target Neighborhood Hits	382	Shared Neighborhood Hits	142
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

CS1A_MOUSE
θ value	0.0148317 (rank : 141)	NC score	0.215919 (rank : 307)
Query Neighborhood Hits	270	Target Neighborhood Hits	360	Shared Neighborhood Hits	135
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

EMR1_HUMAN
θ value	0.0148317 (rank : 142)	NC score	0.593697 (rank : 95)
Query Neighborhood Hits	270	Target Neighborhood Hits	382	Shared Neighborhood Hits	198
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

PGCA_HUMAN
θ value	0.0148317 (rank : 143)	NC score	0.221568 (rank : 299)
Query Neighborhood Hits	270	Target Neighborhood Hits	821	Shared Neighborhood Hits	144
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

TDGF2_HUMAN
θ value	0.0148317 (rank : 144)	NC score	0.389420 (rank : 156)
Query Neighborhood Hits	270	Target Neighborhood Hits	131	Shared Neighborhood Hits	105
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

TIE2_HUMAN
θ value	0.0148317 (rank : 145)	NC score	0.147782 (rank : 379)
Query Neighborhood Hits	270	Target Neighborhood Hits	1192	Shared Neighborhood Hits	187
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TRBM_HUMAN
θ value	0.0148317 (rank : 146)	NC score	0.707882 (rank : 60)
Query Neighborhood Hits	270	Target Neighborhood Hits	339	Shared Neighborhood Hits	213
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

PERT_HUMAN
θ value	0.0193708 (rank : 147)	NC score	0.349852 (rank : 174)
Query Neighborhood Hits	270	Target Neighborhood Hits	221	Shared Neighborhood Hits	159
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

TDGF1_HUMAN
θ value	0.0193708 (rank : 148)	NC score	0.392627 (rank : 154)
Query Neighborhood Hits	270	Target Neighborhood Hits	132	Shared Neighborhood Hits	112
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

C1S_HUMAN
θ value	0.0252991 (rank : 149)	NC score	0.207461 (rank : 316)
Query Neighborhood Hits	270	Target Neighborhood Hits	359	Shared Neighborhood Hits	140
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

EMR1_MOUSE
θ value	0.0252991 (rank : 150)	NC score	0.573883 (rank : 104)
Query Neighborhood Hits	270	Target Neighborhood Hits	349	Shared Neighborhood Hits	199
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

FA7_HUMAN
θ value	0.0252991 (rank : 151)	NC score	0.331608 (rank : 190)
Query Neighborhood Hits	270	Target Neighborhood Hits	404	Shared Neighborhood Hits	204
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

MATN3_HUMAN
θ value	0.0252991 (rank : 152)	NC score	0.588496 (rank : 98)
Query Neighborhood Hits	270	Target Neighborhood Hits	268	Shared Neighborhood Hits	181
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

TIE1_HUMAN
θ value	0.0252991 (rank : 153)	NC score	0.173241 (rank : 356)
Query Neighborhood Hits	270	Target Neighborhood Hits	1241	Shared Neighborhood Hits	194
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

MATN1_HUMAN
θ value	0.0330416 (rank : 154)	NC score	0.292960 (rank : 237)
Query Neighborhood Hits	270	Target Neighborhood Hits	191	Shared Neighborhood Hits	136
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

UROM_HUMAN
θ value	0.0330416 (rank : 155)	NC score	0.632290 (rank : 84)
Query Neighborhood Hits	270	Target Neighborhood Hits	284	Shared Neighborhood Hits	201
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

KRA58_HUMAN
θ value	0.0431538 (rank : 156)	NC score	0.413923 (rank : 150)
Query Neighborhood Hits	270	Target Neighborhood Hits	324	Shared Neighborhood Hits	128
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

MATN1_MOUSE
θ value	0.0431538 (rank : 157)	NC score	0.290556 (rank : 242)
Query Neighborhood Hits	270	Target Neighborhood Hits	186	Shared Neighborhood Hits	130
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

FA7_MOUSE
θ value	0.0563607 (rank : 158)	NC score	0.290545 (rank : 243)
Query Neighborhood Hits	270	Target Neighborhood Hits	374	Shared Neighborhood Hits	186
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

TIE1_MOUSE
θ value	0.0563607 (rank : 159)	NC score	0.168394 (rank : 360)
Query Neighborhood Hits	270	Target Neighborhood Hits	1266	Shared Neighborhood Hits	188
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

LAMC1_HUMAN
θ value	0.0736092 (rank : 160)	NC score	0.308535 (rank : 221)
Query Neighborhood Hits	270	Target Neighborhood Hits	922	Shared Neighborhood Hits	182
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

PGCB_HUMAN
θ value	0.0736092 (rank : 161)	NC score	0.269899 (rank : 268)
Query Neighborhood Hits	270	Target Neighborhood Hits	478	Shared Neighborhood Hits	140
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

TLL2_MOUSE
θ value	0.0736092 (rank : 162)	NC score	0.330563 (rank : 192)
Query Neighborhood Hits	270	Target Neighborhood Hits	240	Shared Neighborhood Hits	153
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

VLDLR_HUMAN
θ value	0.0736092 (rank : 163)	NC score	0.515891 (rank : 123)
Query Neighborhood Hits	270	Target Neighborhood Hits	383	Shared Neighborhood Hits	209
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
θ value	0.0736092 (rank : 164)	NC score	0.518167 (rank : 121)
Query Neighborhood Hits	270	Target Neighborhood Hits	360	Shared Neighborhood Hits	210
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

BMP1_MOUSE
θ value	0.0961366 (rank : 165)	NC score	0.342171 (rank : 181)
Query Neighborhood Hits	270	Target Neighborhood Hits	236	Shared Neighborhood Hits	157
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

COMP_HUMAN
θ value	0.0961366 (rank : 166)	NC score	0.501159 (rank : 131)
Query Neighborhood Hits	270	Target Neighborhood Hits	258	Shared Neighborhood Hits	179
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

STAB2_HUMAN
θ value	0.0961366 (rank : 167)	NC score	0.596301 (rank : 93)
Query Neighborhood Hits	270	Target Neighborhood Hits	534	Shared Neighborhood Hits	226
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

TDGF1_MOUSE
θ value	0.0961366 (rank : 168)	NC score	0.424902 (rank : 148)
Query Neighborhood Hits	270	Target Neighborhood Hits	146	Shared Neighborhood Hits	116
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

ADAM8_HUMAN
θ value	0.125558 (rank : 169)	NC score	0.134117 (rank : 400)
Query Neighborhood Hits	270	Target Neighborhood Hits	327	Shared Neighborhood Hits	119
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ATRN_HUMAN
θ value	0.125558 (rank : 170)	NC score	0.321218 (rank : 202)
Query Neighborhood Hits	270	Target Neighborhood Hits	525	Shared Neighborhood Hits	179
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATRN_MOUSE
θ value	0.125558 (rank : 171)	NC score	0.325318 (rank : 199)
Query Neighborhood Hits	270	Target Neighborhood Hits	519	Shared Neighborhood Hits	177
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

BMP1_HUMAN
θ value	0.125558 (rank : 172)	NC score	0.340248 (rank : 186)
Query Neighborhood Hits	270	Target Neighborhood Hits	233	Shared Neighborhood Hits	156
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

CELR2_HUMAN
θ value	0.125558 (rank : 173)	NC score	0.319994 (rank : 203)
Query Neighborhood Hits	270	Target Neighborhood Hits	657	Shared Neighborhood Hits	230
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CELR3_MOUSE
θ value	0.125558 (rank : 174)	NC score	0.310399 (rank : 218)
Query Neighborhood Hits	270	Target Neighborhood Hits	687	Shared Neighborhood Hits	213
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

PGCB_MOUSE
θ value	0.125558 (rank : 175)	NC score	0.289244 (rank : 247)
Query Neighborhood Hits	270	Target Neighborhood Hits	459	Shared Neighborhood Hits	149
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

CD97_MOUSE
θ value	0.163984 (rank : 176)	NC score	0.506153 (rank : 127)
Query Neighborhood Hits	270	Target Neighborhood Hits	295	Shared Neighborhood Hits	187
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CELR2_MOUSE
θ value	0.163984 (rank : 177)	NC score	0.286793 (rank : 252)
Query Neighborhood Hits	270	Target Neighborhood Hits	584	Shared Neighborhood Hits	204
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

COMP_MOUSE
θ value	0.163984 (rank : 178)	NC score	0.517753 (rank : 122)
Query Neighborhood Hits	270	Target Neighborhood Hits	290	Shared Neighborhood Hits	188
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

PGBM_MOUSE
θ value	0.163984 (rank : 179)	NC score	0.319949 (rank : 204)
Query Neighborhood Hits	270	Target Neighborhood Hits	1073	Shared Neighborhood Hits	216
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

UROM_MOUSE
θ value	0.163984 (rank : 180)	NC score	0.621117 (rank : 86)
Query Neighborhood Hits	270	Target Neighborhood Hits	276	Shared Neighborhood Hits	194
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

ITB3_HUMAN
θ value	0.21417 (rank : 181)	NC score	0.316454 (rank : 212)
Query Neighborhood Hits	270	Target Neighborhood Hits	325	Shared Neighborhood Hits	184
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

UROK_HUMAN
θ value	0.21417 (rank : 182)	NC score	0.121932 (rank : 417)
Query Neighborhood Hits	270	Target Neighborhood Hits	272	Shared Neighborhood Hits	106
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

ADA19_HUMAN
θ value	0.279714 (rank : 183)	NC score	0.125528 (rank : 413)
Query Neighborhood Hits	270	Target Neighborhood Hits	381	Shared Neighborhood Hits	119
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ADA19_MOUSE
θ value	0.279714 (rank : 184)	NC score	0.128243 (rank : 409)
Query Neighborhood Hits	270	Target Neighborhood Hits	315	Shared Neighborhood Hits	127
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ADA33_MOUSE
θ value	0.279714 (rank : 185)	NC score	0.113333 (rank : 429)
Query Neighborhood Hits	270	Target Neighborhood Hits	231	Shared Neighborhood Hits	101
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

HABP2_MOUSE
θ value	0.279714 (rank : 186)	NC score	0.328386 (rank : 193)
Query Neighborhood Hits	270	Target Neighborhood Hits	445	Shared Neighborhood Hits	189
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

LRP5_MOUSE
θ value	0.279714 (rank : 187)	NC score	0.282414 (rank : 259)
Query Neighborhood Hits	270	Target Neighborhood Hits	236	Shared Neighborhood Hits	128
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

MFGM_HUMAN
θ value	0.279714 (rank : 188)	NC score	0.220834 (rank : 302)
Query Neighborhood Hits	270	Target Neighborhood Hits	150	Shared Neighborhood Hits	107
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

NRX3A_HUMAN
θ value	0.279714 (rank : 189)	NC score	0.203316 (rank : 325)
Query Neighborhood Hits	270	Target Neighborhood Hits	164	Shared Neighborhood Hits	105
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

PGBM_HUMAN
θ value	0.279714 (rank : 190)	NC score	0.316485 (rank : 211)
Query Neighborhood Hits	270	Target Neighborhood Hits	1113	Shared Neighborhood Hits	219
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

TSP4_HUMAN
θ value	0.279714 (rank : 191)	NC score	0.544555 (rank : 114)
Query Neighborhood Hits	270	Target Neighborhood Hits	277	Shared Neighborhood Hits	195
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

LRP5_HUMAN
θ value	0.365318 (rank : 192)	NC score	0.280157 (rank : 263)
Query Neighborhood Hits	270	Target Neighborhood Hits	224	Shared Neighborhood Hits	127
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

CFC1_HUMAN
θ value	0.47712 (rank : 193)	NC score	0.417700 (rank : 149)
Query Neighborhood Hits	270	Target Neighborhood Hits	148	Shared Neighborhood Hits	123
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

FA12_HUMAN
θ value	0.47712 (rank : 194)	NC score	0.247780 (rank : 281)
Query Neighborhood Hits	270	Target Neighborhood Hits	425	Shared Neighborhood Hits	170
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

LAMA1_MOUSE
θ value	0.47712 (rank : 195)	NC score	0.354187 (rank : 171)
Query Neighborhood Hits	270	Target Neighborhood Hits	838	Shared Neighborhood Hits	203
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LDLR_MOUSE
θ value	0.47712 (rank : 196)	NC score	0.497160 (rank : 135)
Query Neighborhood Hits	270	Target Neighborhood Hits	382	Shared Neighborhood Hits	208
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

MATN4_MOUSE
θ value	0.47712 (rank : 197)	NC score	0.564456 (rank : 107)
Query Neighborhood Hits	270	Target Neighborhood Hits	277	Shared Neighborhood Hits	180
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

ADA32_HUMAN
θ value	0.62314 (rank : 198)	NC score	0.094684 (rank : 464)
Query Neighborhood Hits	270	Target Neighborhood Hits	216	Shared Neighborhood Hits	106
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

KRA53_HUMAN
θ value	0.62314 (rank : 199)	NC score	0.411613 (rank : 151)
Query Neighborhood Hits	270	Target Neighborhood Hits	331	Shared Neighborhood Hits	140
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

SUSD1_HUMAN
θ value	0.62314 (rank : 200)	NC score	0.654407 (rank : 77)
Query Neighborhood Hits	270	Target Neighborhood Hits	285	Shared Neighborhood Hits	190
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TSP3_MOUSE
θ value	0.62314 (rank : 201)	NC score	0.485778 (rank : 137)
Query Neighborhood Hits	270	Target Neighborhood Hits	247	Shared Neighborhood Hits	175
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

ADA33_HUMAN
θ value	0.813845 (rank : 202)	NC score	0.116624 (rank : 427)
Query Neighborhood Hits	270	Target Neighborhood Hits	264	Shared Neighborhood Hits	111
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

AGRIN_HUMAN
θ value	0.813845 (rank : 203)	NC score	0.470208 (rank : 142)
Query Neighborhood Hits	270	Target Neighborhood Hits	582	Shared Neighborhood Hits	214
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

CLC14_HUMAN
θ value	0.813845 (rank : 204)	NC score	0.322574 (rank : 201)
Query Neighborhood Hits	270	Target Neighborhood Hits	143	Shared Neighborhood Hits	113
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

ELTD1_HUMAN
θ value	0.813845 (rank : 205)	NC score	0.363344 (rank : 166)
Query Neighborhood Hits	270	Target Neighborhood Hits	269	Shared Neighborhood Hits	167
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

ITB3_MOUSE
θ value	0.813845 (rank : 206)	NC score	0.299082 (rank : 231)
Query Neighborhood Hits	270	Target Neighborhood Hits	319	Shared Neighborhood Hits	175
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

LDLR_HUMAN
θ value	0.813845 (rank : 207)	NC score	0.525887 (rank : 118)
Query Neighborhood Hits	270	Target Neighborhood Hits	375	Shared Neighborhood Hits	214
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

MT4_MOUSE
θ value	0.813845 (rank : 208)	NC score	0.159809 (rank : 370)
Query Neighborhood Hits	270	Target Neighborhood Hits	102	Shared Neighborhood Hits	44
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

TPA_HUMAN
θ value	0.813845 (rank : 209)	NC score	0.178781 (rank : 348)
Query Neighborhood Hits	270	Target Neighborhood Hits	324	Shared Neighborhood Hits	137
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

C1RA_MOUSE
θ value	1.06291 (rank : 210)	NC score	0.236884 (rank : 287)
Query Neighborhood Hits	270	Target Neighborhood Hits	379	Shared Neighborhood Hits	149
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1RB_MOUSE
θ value	1.06291 (rank : 211)	NC score	0.233095 (rank : 292)
Query Neighborhood Hits	270	Target Neighborhood Hits	380	Shared Neighborhood Hits	149
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

NTNG2_MOUSE
θ value	1.06291 (rank : 212)	NC score	0.346412 (rank : 179)
Query Neighborhood Hits	270	Target Neighborhood Hits	276	Shared Neighborhood Hits	173
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

TSP4_MOUSE
θ value	1.06291 (rank : 213)	NC score	0.544415 (rank : 115)
Query Neighborhood Hits	270	Target Neighborhood Hits	276	Shared Neighborhood Hits	195
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

5HT3R_MOUSE
θ value	1.38821 (rank : 214)	NC score	0.004553 (rank : 740)
Query Neighborhood Hits	270	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	P23979, Q61225, Q61226	Gene names	Htr3a, 5ht3, Htr3
Domain Architecture
Description	5-hydroxytryptamine 3 receptor precursor (5-HT-3) (Serotonin-gated ion channel receptor) (5-HT3R).

ADA11_HUMAN
θ value	1.38821 (rank : 215)	NC score	0.138361 (rank : 390)
Query Neighborhood Hits	270	Target Neighborhood Hits	259	Shared Neighborhood Hits	127
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA11_MOUSE
θ value	1.38821 (rank : 216)	NC score	0.137559 (rank : 392)
Query Neighborhood Hits	270	Target Neighborhood Hits	263	Shared Neighborhood Hits	128
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADAM8_MOUSE
θ value	1.38821 (rank : 217)	NC score	0.142614 (rank : 383)
Query Neighborhood Hits	270	Target Neighborhood Hits	326	Shared Neighborhood Hits	117
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

HGFA_MOUSE
θ value	1.38821 (rank : 218)	NC score	0.267940 (rank : 269)
Query Neighborhood Hits	270	Target Neighborhood Hits	419	Shared Neighborhood Hits	180
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

LAMA1_HUMAN
θ value	1.38821 (rank : 219)	NC score	0.349713 (rank : 175)
Query Neighborhood Hits	270	Target Neighborhood Hits	804	Shared Neighborhood Hits	197
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LRP8_MOUSE
θ value	1.38821 (rank : 220)	NC score	0.506802 (rank : 125)
Query Neighborhood Hits	270	Target Neighborhood Hits	385	Shared Neighborhood Hits	200
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

MT4_HUMAN
θ value	1.38821 (rank : 221)	NC score	0.132338 (rank : 403)
Query Neighborhood Hits	270	Target Neighborhood Hits	83	Shared Neighborhood Hits	32
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MYH10_HUMAN
θ value	1.38821 (rank : 222)	NC score	-0.001861 (rank : 742)
Query Neighborhood Hits	270	Target Neighborhood Hits	1620	Shared Neighborhood Hits	13
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
θ value	1.38821 (rank : 223)	NC score	-0.001856 (rank : 741)
Query Neighborhood Hits	270	Target Neighborhood Hits	1612	Shared Neighborhood Hits	13
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

NRX2A_HUMAN
θ value	1.38821 (rank : 224)	NC score	0.195521 (rank : 330)
Query Neighborhood Hits	270	Target Neighborhood Hits	614	Shared Neighborhood Hits	111
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

RELN_MOUSE
θ value	1.38821 (rank : 225)	NC score	0.204429 (rank : 319)
Query Neighborhood Hits	270	Target Neighborhood Hits	235	Shared Neighborhood Hits	132
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

TPA_MOUSE
θ value	1.38821 (rank : 226)	NC score	0.179762 (rank : 345)
Query Neighborhood Hits	270	Target Neighborhood Hits	335	Shared Neighborhood Hits	135
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

UROK_MOUSE
θ value	1.38821 (rank : 227)	NC score	0.119240 (rank : 422)
Query Neighborhood Hits	270	Target Neighborhood Hits	273	Shared Neighborhood Hits	107
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

KRA57_HUMAN
θ value	1.81305 (rank : 228)	NC score	0.339213 (rank : 187)
Query Neighborhood Hits	270	Target Neighborhood Hits	269	Shared Neighborhood Hits	113
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

LAMA3_MOUSE
θ value	1.81305 (rank : 229)	NC score	0.289565 (rank : 246)
Query Neighborhood Hits	270	Target Neighborhood Hits	859	Shared Neighborhood Hits	200
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LRP8_HUMAN
θ value	1.81305 (rank : 230)	NC score	0.504075 (rank : 129)
Query Neighborhood Hits	270	Target Neighborhood Hits	346	Shared Neighborhood Hits	200
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

TENX_HUMAN
θ value	2.36792 (rank : 231)	NC score	0.443677 (rank : 145)
Query Neighborhood Hits	270	Target Neighborhood Hits	789	Shared Neighborhood Hits	208
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

ALK_HUMAN
θ value	3.0926 (rank : 232)	NC score	0.006083 (rank : 738)
Query Neighborhood Hits	270	Target Neighborhood Hits	795	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

NAGPA_HUMAN
θ value	3.0926 (rank : 233)	NC score	0.404014 (rank : 152)
Query Neighborhood Hits	270	Target Neighborhood Hits	282	Shared Neighborhood Hits	150
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

RELN_HUMAN
θ value	3.0926 (rank : 234)	NC score	0.194375 (rank : 331)
Query Neighborhood Hits	270	Target Neighborhood Hits	233	Shared Neighborhood Hits	130
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

TIE2_MOUSE
θ value	3.0926 (rank : 235)	NC score	0.141046 (rank : 385)
Query Neighborhood Hits	270	Target Neighborhood Hits	1204	Shared Neighborhood Hits	188
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

UROL1_MOUSE
θ value	3.0926 (rank : 236)	NC score	0.303490 (rank : 227)
Query Neighborhood Hits	270	Target Neighborhood Hits	235	Shared Neighborhood Hits	132
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

5HT4R_HUMAN
θ value	4.03905 (rank : 237)	NC score	-0.008620 (rank : 746)
Query Neighborhood Hits	270	Target Neighborhood Hits	854	Shared Neighborhood Hits	3
SwissProt Accessions	Q13639, Q96KH9, Q96KI0, Q9H199, Q9NY73, Q9UBM6, Q9UBT4, Q9UE22, Q9UE23, Q9UQR6	Gene names	HTR4
Domain Architecture
Description	5-hydroxytryptamine 4 receptor (5-HT-4) (Serotonin receptor 4) (5- HT4).

ALK_MOUSE
θ value	4.03905 (rank : 238)	NC score	0.005716 (rank : 739)
Query Neighborhood Hits	270	Target Neighborhood Hits	811	Shared Neighborhood Hits	26
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

C1R_HUMAN
θ value	4.03905 (rank : 239)	NC score	0.214635 (rank : 309)
Query Neighborhood Hits	270	Target Neighborhood Hits	364	Shared Neighborhood Hits	138
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

CLC14_MOUSE
θ value	4.03905 (rank : 240)	NC score	0.319639 (rank : 205)
Query Neighborhood Hits	270	Target Neighborhood Hits	120	Shared Neighborhood Hits	110
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

CU005_HUMAN
θ value	4.03905 (rank : 241)	NC score	0.016849 (rank : 735)
Query Neighborhood Hits	270	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y3R5, Q9UEZ3	Gene names	C21orf5, KIAA0933
Domain Architecture
Description	Protein C21orf5.

HABP2_HUMAN
θ value	4.03905 (rank : 242)	NC score	0.326530 (rank : 195)
Query Neighborhood Hits	270	Target Neighborhood Hits	431	Shared Neighborhood Hits	181
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

LAMA2_MOUSE
θ value	4.03905 (rank : 243)	NC score	0.296425 (rank : 234)
Query Neighborhood Hits	270	Target Neighborhood Hits	1198	Shared Neighborhood Hits	195
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

NTNG2_HUMAN
θ value	4.03905 (rank : 244)	NC score	0.325253 (rank : 200)
Query Neighborhood Hits	270	Target Neighborhood Hits	276	Shared Neighborhood Hits	165
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

TENA_MOUSE
θ value	4.03905 (rank : 245)	NC score	0.443925 (rank : 144)
Query Neighborhood Hits	270	Target Neighborhood Hits	596	Shared Neighborhood Hits	202
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

UROL1_HUMAN
θ value	4.03905 (rank : 246)	NC score	0.278084 (rank : 264)
Query Neighborhood Hits	270	Target Neighborhood Hits	213	Shared Neighborhood Hits	126
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

GRN_MOUSE
θ value	5.27518 (rank : 247)	NC score	0.389828 (rank : 155)
Query Neighborhood Hits	270	Target Neighborhood Hits	248	Shared Neighborhood Hits	128
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

ITB4_HUMAN
θ value	5.27518 (rank : 248)	NC score	0.283100 (rank : 258)
Query Neighborhood Hits	270	Target Neighborhood Hits	458	Shared Neighborhood Hits	170
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

PGH1_MOUSE
θ value	5.27518 (rank : 249)	NC score	0.159378 (rank : 371)
Query Neighborhood Hits	270	Target Neighborhood Hits	100	Shared Neighborhood Hits	69
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

STAB2_MOUSE
θ value	5.27518 (rank : 250)	NC score	0.581961 (rank : 102)
Query Neighborhood Hits	270	Target Neighborhood Hits	528	Shared Neighborhood Hits	225
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

TSP3_HUMAN
θ value	5.27518 (rank : 251)	NC score	0.473760 (rank : 139)
Query Neighborhood Hits	270	Target Neighborhood Hits	250	Shared Neighborhood Hits	175
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

EMR3_HUMAN
θ value	6.88961 (rank : 252)	NC score	0.291042 (rank : 241)
Query Neighborhood Hits	270	Target Neighborhood Hits	245	Shared Neighborhood Hits	152
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

KRA51_HUMAN
θ value	6.88961 (rank : 253)	NC score	0.386193 (rank : 158)
Query Neighborhood Hits	270	Target Neighborhood Hits	288	Shared Neighborhood Hits	125
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA56_HUMAN
θ value	6.88961 (rank : 254)	NC score	0.259901 (rank : 272)
Query Neighborhood Hits	270	Target Neighborhood Hits	207	Shared Neighborhood Hits	93
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

LMNA_HUMAN
θ value	6.88961 (rank : 255)	NC score	-0.002263 (rank : 743)
Query Neighborhood Hits	270	Target Neighborhood Hits	653	Shared Neighborhood Hits	10
SwissProt Accessions	P02545, P02546, Q969I8, Q96JA2	Gene names	LMNA, LMN1
Domain Architecture
Description	Lamin-A/C (70 kDa lamin) (NY-REN-32 antigen).

LMNA_MOUSE
θ value	6.88961 (rank : 256)	NC score	-0.002463 (rank : 744)
Query Neighborhood Hits	270	Target Neighborhood Hits	661	Shared Neighborhood Hits	9
SwissProt Accessions	P48678, P11516, P97859, Q3TIH0, Q3TTS8, Q3UCA0, Q3UCJ8, Q91WF2, Q9DC21	Gene names	Lmna, Lmn1
Domain Architecture
Description	Lamin-A/C.

RRBP1_HUMAN
θ value	6.88961 (rank : 257)	NC score	-0.003694 (rank : 745)
Query Neighborhood Hits	270	Target Neighborhood Hits	1306	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

ZFY27_MOUSE
θ value	6.88961 (rank : 258)	NC score	0.007646 (rank : 737)
Query Neighborhood Hits	270	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q3TXX3, Q8CFP8	Gene names	Zfyve27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

5HT4R_MOUSE
θ value	8.99809 (rank : 259)	NC score	-0.009315 (rank : 747)
Query Neighborhood Hits	270	Target Neighborhood Hits	856	Shared Neighborhood Hits	3
SwissProt Accessions	P97288, O89003, O89004, Q9R2A4	Gene names	Htr4
Domain Architecture
Description	5-hydroxytryptamine 4 receptor (5-HT-4) (Serotonin receptor 4) (5- HT4).

ADA28_MOUSE
θ value	8.99809 (rank : 260)	NC score	0.084531 (rank : 509)
Query Neighborhood Hits	270	Target Neighborhood Hits	241	Shared Neighborhood Hits	98
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ADAM9_MOUSE
θ value	8.99809 (rank : 261)	NC score	0.111937 (rank : 430)
Query Neighborhood Hits	270	Target Neighborhood Hits	325	Shared Neighborhood Hits	123
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ASTN_HUMAN
θ value	8.99809 (rank : 262)	NC score	0.183450 (rank : 340)
Query Neighborhood Hits	270	Target Neighborhood Hits	105	Shared Neighborhood Hits	80
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

ASTN_MOUSE
θ value	8.99809 (rank : 263)	NC score	0.179374 (rank : 346)
Query Neighborhood Hits	270	Target Neighborhood Hits	98	Shared Neighborhood Hits	78
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

ITB6_MOUSE
θ value	8.99809 (rank : 264)	NC score	0.330621 (rank : 191)
Query Neighborhood Hits	270	Target Neighborhood Hits	341	Shared Neighborhood Hits	181
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB8_HUMAN
θ value	8.99809 (rank : 265)	NC score	0.239651 (rank : 284)
Query Neighborhood Hits	270	Target Neighborhood Hits	280	Shared Neighborhood Hits	148
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

LAMB2_MOUSE
θ value	8.99809 (rank : 266)	NC score	0.340992 (rank : 184)
Query Neighborhood Hits	270	Target Neighborhood Hits	722	Shared Neighborhood Hits	186
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

PGH1_HUMAN
θ value	8.99809 (rank : 267)	NC score	0.134820 (rank : 399)
Query Neighborhood Hits	270	Target Neighborhood Hits	91	Shared Neighborhood Hits	64
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

SEPP1_HUMAN
θ value	8.99809 (rank : 268)	NC score	0.019995 (rank : 734)
Query Neighborhood Hits	270	Target Neighborhood Hits	28	Shared Neighborhood Hits	7
SwissProt Accessions	P49908, Q6PD59, Q6PI43, Q6PI87, Q6PJF9	Gene names	SEPP1, SELP
Domain Architecture
Description	Selenoprotein P precursor (SeP).

SSPO_MOUSE
θ value	8.99809 (rank : 269)	NC score	0.287121 (rank : 251)
Query Neighborhood Hits	270	Target Neighborhood Hits	800	Shared Neighborhood Hits	196
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

VEGFD_HUMAN
θ value	8.99809 (rank : 270)	NC score	0.011980 (rank : 736)
Query Neighborhood Hits	270	Target Neighborhood Hits	48	Shared Neighborhood Hits	12
SwissProt Accessions	O43915	Gene names	FIGF, VEGFD
Domain Architecture
Description	Vascular endothelial growth factor D precursor (VEGF-D) (c-fos-induced growth factor) (FIGF).

ACRO_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.064911 (rank : 596)
Query Neighborhood Hits	270	Target Neighborhood Hits	291	Shared Neighborhood Hits	30
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

ACRO_MOUSE
θ value	θ > 10 (rank : 272)	NC score	0.064546 (rank : 598)
Query Neighborhood Hits	270	Target Neighborhood Hits	185	Shared Neighborhood Hits	28
SwissProt Accessions	P23578	Gene names	Acr
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

AD26A_MOUSE
θ value	θ > 10 (rank : 273)	NC score	0.054323 (rank : 687)
Query Neighborhood Hits	270	Target Neighborhood Hits	165	Shared Neighborhood Hits	61
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

ADA10_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.099406 (rank : 454)
Query Neighborhood Hits	270	Target Neighborhood Hits	189	Shared Neighborhood Hits	76
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ADA10_MOUSE
θ value	θ > 10 (rank : 275)	NC score	0.090918 (rank : 481)
Query Neighborhood Hits	270	Target Neighborhood Hits	194	Shared Neighborhood Hits	68
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA12_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.090384 (rank : 485)
Query Neighborhood Hits	270	Target Neighborhood Hits	224	Shared Neighborhood Hits	99
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA12_MOUSE
θ value	θ > 10 (rank : 277)	NC score	0.073457 (rank : 549)
Query Neighborhood Hits	270	Target Neighborhood Hits	474	Shared Neighborhood Hits	82
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA15_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.102845 (rank : 446)
Query Neighborhood Hits	270	Target Neighborhood Hits	288	Shared Neighborhood Hits	117
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

ADA15_MOUSE
θ value	θ > 10 (rank : 279)	NC score	0.126903 (rank : 411)
Query Neighborhood Hits	270	Target Neighborhood Hits	324	Shared Neighborhood Hits	130
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADA17_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.098442 (rank : 457)
Query Neighborhood Hits	270	Target Neighborhood Hits	223	Shared Neighborhood Hits	82
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ADA17_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.076077 (rank : 541)
Query Neighborhood Hits	270	Target Neighborhood Hits	201	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

ADA18_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.084901 (rank : 507)
Query Neighborhood Hits	270	Target Neighborhood Hits	184	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

ADA18_MOUSE
θ value	θ > 10 (rank : 283)	NC score	0.099627 (rank : 453)
Query Neighborhood Hits	270	Target Neighborhood Hits	227	Shared Neighborhood Hits	94
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ADA20_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.050452 (rank : 730)
Query Neighborhood Hits	270	Target Neighborhood Hits	143	Shared Neighborhood Hits	49
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

ADA21_HUMAN
θ value	θ > 10 (rank : 285)	NC score	0.084388 (rank : 510)
Query Neighborhood Hits	270	Target Neighborhood Hits	181	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

ADA21_MOUSE
θ value	θ > 10 (rank : 286)	NC score	0.093294 (rank : 471)
Query Neighborhood Hits	270	Target Neighborhood Hits	172	Shared Neighborhood Hits	90
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

ADA22_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.084640 (rank : 508)
Query Neighborhood Hits	270	Target Neighborhood Hits	211	Shared Neighborhood Hits	87
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ADA22_MOUSE
θ value	θ > 10 (rank : 288)	NC score	0.089627 (rank : 486)
Query Neighborhood Hits	270	Target Neighborhood Hits	225	Shared Neighborhood Hits	94
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ADA23_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.128092 (rank : 410)
Query Neighborhood Hits	270	Target Neighborhood Hits	235	Shared Neighborhood Hits	120
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA23_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.123320 (rank : 415)
Query Neighborhood Hits	270	Target Neighborhood Hits	245	Shared Neighborhood Hits	130
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA24_MOUSE
θ value	θ > 10 (rank : 291)	NC score	0.075492 (rank : 542)
Query Neighborhood Hits	270	Target Neighborhood Hits	230	Shared Neighborhood Hits	88
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ADA25_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.080978 (rank : 525)
Query Neighborhood Hits	270	Target Neighborhood Hits	213	Shared Neighborhood Hits	85
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

ADA28_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.085882 (rank : 503)
Query Neighborhood Hits	270	Target Neighborhood Hits	244	Shared Neighborhood Hits	101
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ADA29_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.070370 (rank : 563)
Query Neighborhood Hits	270	Target Neighborhood Hits	247	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

ADA30_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.096542 (rank : 461)
Query Neighborhood Hits	270	Target Neighborhood Hits	391	Shared Neighborhood Hits	92
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ADA32_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.077459 (rank : 536)
Query Neighborhood Hits	270	Target Neighborhood Hits	219	Shared Neighborhood Hits	90
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADAM2_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.088808 (rank : 490)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	82
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

ADAM2_MOUSE
θ value	θ > 10 (rank : 298)	NC score	0.092851 (rank : 474)
Query Neighborhood Hits	270	Target Neighborhood Hits	209	Shared Neighborhood Hits	96
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

ADAM7_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.098269 (rank : 458)
Query Neighborhood Hits	270	Target Neighborhood Hits	221	Shared Neighborhood Hits	100
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ADAM7_MOUSE
θ value	θ > 10 (rank : 300)	NC score	0.074771 (rank : 546)
Query Neighborhood Hits	270	Target Neighborhood Hits	200	Shared Neighborhood Hits	87
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADAM9_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.103267 (rank : 445)
Query Neighborhood Hits	270	Target Neighborhood Hits	243	Shared Neighborhood Hits	110
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

ADM1A_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.087885 (rank : 493)
Query Neighborhood Hits	270	Target Neighborhood Hits	230	Shared Neighborhood Hits	104
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ADM1B_MOUSE
θ value	θ > 10 (rank : 303)	NC score	0.078649 (rank : 533)
Query Neighborhood Hits	270	Target Neighborhood Hits	236	Shared Neighborhood Hits	90
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

APOA_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.062901 (rank : 610)
Query Neighborhood Hits	270	Target Neighborhood Hits	221	Shared Neighborhood Hits	31
SwissProt Accessions	P08519	Gene names	LPA
Domain Architecture
Description	Apolipoprotein(a) precursor (EC 3.4.21.-) (Apo(a)) (Lp(a)).

APR3_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.129740 (rank : 406)
Query Neighborhood Hits	270	Target Neighborhood Hits	50	Shared Neighborhood Hits	45
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

APR3_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.140293 (rank : 387)
Query Neighborhood Hits	270	Target Neighborhood Hits	61	Shared Neighborhood Hits	47
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

ASTL_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.052416 (rank : 707)
Query Neighborhood Hits	270	Target Neighborhood Hits	252	Shared Neighborhood Hits	12
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

BAI1_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.051494 (rank : 720)
Query Neighborhood Hits	270	Target Neighborhood Hits	375	Shared Neighborhood Hits	30
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BMPER_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.102323 (rank : 449)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

BMPER_MOUSE
θ value	θ > 10 (rank : 310)	NC score	0.107088 (rank : 438)
Query Neighborhood Hits	270	Target Neighborhood Hits	194	Shared Neighborhood Hits	68
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

BSSP4_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.063175 (rank : 609)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	28
SwissProt Accessions	Q9GZN4, O43342, Q6UXE0	Gene names	PRSS22, BSSP4, PRSS26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

BSSP4_MOUSE
θ value	θ > 10 (rank : 312)	NC score	0.063587 (rank : 606)
Query Neighborhood Hits	270	Target Neighborhood Hits	179	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ER10	Gene names	Prss22, Bssp4, Prss26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

BTC_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.071470 (rank : 557)
Query Neighborhood Hits	270	Target Neighborhood Hits	70	Shared Neighborhood Hits	34
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

BTC_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.086611 (rank : 497)
Query Neighborhood Hits	270	Target Neighborhood Hits	67	Shared Neighborhood Hits	41
SwissProt Accessions	Q05928	Gene names	Btc, Bcn
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

CATG_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.058716 (rank : 653)
Query Neighborhood Hits	270	Target Neighborhood Hits	174	Shared Neighborhood Hits	28
SwissProt Accessions	P08311	Gene names	CTSG
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (CG).

CATG_MOUSE
θ value	θ > 10 (rank : 316)	NC score	0.059322 (rank : 649)
Query Neighborhood Hits	270	Target Neighborhood Hits	174	Shared Neighborhood Hits	28
SwissProt Accessions	P28293	Gene names	Ctsg
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (Vimentin-specific protease) (VSP).

CD2A1_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.053636 (rank : 695)
Query Neighborhood Hits	270	Target Neighborhood Hits	206	Shared Neighborhood Hits	8
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

CD320_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.129258 (rank : 408)
Query Neighborhood Hits	270	Target Neighborhood Hits	103	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

CDN2B_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.053740 (rank : 694)
Query Neighborhood Hits	270	Target Neighborhood Hits	196	Shared Neighborhood Hits	8
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

CFAB_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.072694 (rank : 551)
Query Neighborhood Hits	270	Target Neighborhood Hits	251	Shared Neighborhood Hits	40
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAB_MOUSE
θ value	θ > 10 (rank : 321)	NC score	0.083332 (rank : 513)
Query Neighborhood Hits	270	Target Neighborhood Hits	262	Shared Neighborhood Hits	46
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAD_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.055771 (rank : 673)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	27
SwissProt Accessions	P00746	Gene names	CFD, DF
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin).

CFAD_MOUSE
θ value	θ > 10 (rank : 323)	NC score	0.055585 (rank : 678)
Query Neighborhood Hits	270	Target Neighborhood Hits	177	Shared Neighborhood Hits	27
SwissProt Accessions	P03953, Q61280	Gene names	Cfd, Adn, Df
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin) (28 kDa adipocyte protein).

CFAI_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.101836 (rank : 450)
Query Neighborhood Hits	270	Target Neighborhood Hits	289	Shared Neighborhood Hits	60
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CFAI_MOUSE
θ value	θ > 10 (rank : 325)	NC score	0.102704 (rank : 447)
Query Neighborhood Hits	270	Target Neighborhood Hits	290	Shared Neighborhood Hits	66
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CFC1_MOUSE
θ value	θ > 10 (rank : 326)	NC score	0.365470 (rank : 165)
Query Neighborhood Hits	270	Target Neighborhood Hits	125	Shared Neighborhood Hits	109
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CLCR_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.066076 (rank : 583)
Query Neighborhood Hits	270	Target Neighborhood Hits	177	Shared Neighborhood Hits	28
SwissProt Accessions	Q99895, O00765, Q9NUH5	Gene names	CTRC, CLCR
Domain Architecture
Description	Caldecrin precursor (EC 3.4.21.2) (Chymotrypsin C).

CNTP1_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.148495 (rank : 378)
Query Neighborhood Hits	270	Target Neighborhood Hits	196	Shared Neighborhood Hits	94
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

CNTP1_MOUSE
θ value	θ > 10 (rank : 329)	NC score	0.140716 (rank : 386)
Query Neighborhood Hits	270	Target Neighborhood Hits	183	Shared Neighborhood Hits	90
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

CNTP2_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.181870 (rank : 342)
Query Neighborhood Hits	270	Target Neighborhood Hits	199	Shared Neighborhood Hits	115
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP2_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.184810 (rank : 339)
Query Neighborhood Hits	270	Target Neighborhood Hits	194	Shared Neighborhood Hits	112
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP3_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.161128 (rank : 369)
Query Neighborhood Hits	270	Target Neighborhood Hits	195	Shared Neighborhood Hits	102
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

CNTP4_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.165227 (rank : 365)
Query Neighborhood Hits	270	Target Neighborhood Hits	187	Shared Neighborhood Hits	101
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CNTP4_MOUSE
θ value	θ > 10 (rank : 334)	NC score	0.171437 (rank : 357)
Query Neighborhood Hits	270	Target Neighborhood Hits	193	Shared Neighborhood Hits	113
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CO2_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.067763 (rank : 570)
Query Neighborhood Hits	270	Target Neighborhood Hits	258	Shared Neighborhood Hits	42
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO2_MOUSE
θ value	θ > 10 (rank : 336)	NC score	0.068883 (rank : 566)
Query Neighborhood Hits	270	Target Neighborhood Hits	250	Shared Neighborhood Hits	43
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO6_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.137336 (rank : 393)
Query Neighborhood Hits	270	Target Neighborhood Hits	331	Shared Neighborhood Hits	106
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CO7_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.138489 (rank : 389)
Query Neighborhood Hits	270	Target Neighborhood Hits	278	Shared Neighborhood Hits	96
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO8A_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.086315 (rank : 499)
Query Neighborhood Hits	270	Target Neighborhood Hits	200	Shared Neighborhood Hits	71
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8A_MOUSE
θ value	θ > 10 (rank : 340)	NC score	0.082224 (rank : 517)
Query Neighborhood Hits	270	Target Neighborhood Hits	182	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8B_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.094482 (rank : 466)
Query Neighborhood Hits	270	Target Neighborhood Hits	199	Shared Neighborhood Hits	66
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO8B_MOUSE
θ value	θ > 10 (rank : 342)	NC score	0.122128 (rank : 416)
Query Neighborhood Hits	270	Target Neighborhood Hits	224	Shared Neighborhood Hits	86
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO9_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.105788 (rank : 442)
Query Neighborhood Hits	270	Target Neighborhood Hits	147	Shared Neighborhood Hits	69
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

CO9_MOUSE
θ value	θ > 10 (rank : 344)	NC score	0.110643 (rank : 433)
Query Neighborhood Hits	270	Target Neighborhood Hits	153	Shared Neighborhood Hits	71
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

CORIN_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.190129 (rank : 335)
Query Neighborhood Hits	270	Target Neighborhood Hits	453	Shared Neighborhood Hits	148
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

CORIN_MOUSE
θ value	θ > 10 (rank : 346)	NC score	0.175165 (rank : 351)
Query Neighborhood Hits	270	Target Neighborhood Hits	451	Shared Neighborhood Hits	146
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

CRAC1_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.318329 (rank : 210)
Query Neighborhood Hits	270	Target Neighborhood Hits	111	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRAC1_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.312701 (rank : 216)
Query Neighborhood Hits	270	Target Neighborhood Hits	112	Shared Neighborhood Hits	93
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CREL1_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.599767 (rank : 91)
Query Neighborhood Hits	270	Target Neighborhood Hits	441	Shared Neighborhood Hits	198
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CRIM1_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.284923 (rank : 255)
Query Neighborhood Hits	270	Target Neighborhood Hits	362	Shared Neighborhood Hits	120
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

CSMD1_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.086177 (rank : 500)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	48
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD1_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.086991 (rank : 495)
Query Neighborhood Hits	270	Target Neighborhood Hits	193	Shared Neighborhood Hits	55
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD2_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.081190 (rank : 524)
Query Neighborhood Hits	270	Target Neighborhood Hits	188	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CSMD3_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.086799 (rank : 496)
Query Neighborhood Hits	270	Target Neighborhood Hits	199	Shared Neighborhood Hits	51
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CTGF_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.057709 (rank : 661)
Query Neighborhood Hits	270	Target Neighborhood Hits	128	Shared Neighborhood Hits	33
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

CTGF_MOUSE
θ value	θ > 10 (rank : 356)	NC score	0.053174 (rank : 701)
Query Neighborhood Hits	270	Target Neighborhood Hits	124	Shared Neighborhood Hits	29
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

CTRB1_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.066671 (rank : 580)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	28
SwissProt Accessions	P17538	Gene names	CTRB1, CTRB
Domain Architecture
Description	Chymotrypsinogen B precursor (EC 3.4.21.1) [Contains: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C].

CTRL_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.067913 (rank : 569)
Query Neighborhood Hits	270	Target Neighborhood Hits	179	Shared Neighborhood Hits	28
SwissProt Accessions	P40313	Gene names	CTRL, CTRL1
Domain Architecture
Description	Chymotrypsin-like protease CTRL-1 precursor (EC 3.4.21.-).

CUZD1_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.086101 (rank : 502)
Query Neighborhood Hits	270	Target Neighborhood Hits	89	Shared Neighborhood Hits	26
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

CUZD1_MOUSE
θ value	θ > 10 (rank : 360)	NC score	0.081877 (rank : 520)
Query Neighborhood Hits	270	Target Neighborhood Hits	91	Shared Neighborhood Hits	25
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

CYR61_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.058210 (rank : 657)
Query Neighborhood Hits	270	Target Neighborhood Hits	159	Shared Neighborhood Hits	41
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

CYR61_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.061175 (rank : 623)
Query Neighborhood Hits	270	Target Neighborhood Hits	156	Shared Neighborhood Hits	39
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

DCBD1_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.073649 (rank : 548)
Query Neighborhood Hits	270	Target Neighborhood Hits	110	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD1_MOUSE
θ value	θ > 10 (rank : 364)	NC score	0.075196 (rank : 545)
Query Neighborhood Hits	270	Target Neighborhood Hits	89	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD2_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.071773 (rank : 555)
Query Neighborhood Hits	270	Target Neighborhood Hits	118	Shared Neighborhood Hits	26
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

DCBD2_MOUSE
θ value	θ > 10 (rank : 366)	NC score	0.068380 (rank : 567)
Query Neighborhood Hits	270	Target Neighborhood Hits	113	Shared Neighborhood Hits	26
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

DESC4_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.065242 (rank : 592)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BZ10, Q8BZ04	Gene names	Desc4
Domain Architecture	No domain graphic available
Description	Serine protease DESC4 precursor (EC 3.4.21.-) [Contains: Serine protease DESC4 non-catalytic chain; Serine protease DESC4 catalytic chain].

DKK3_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.053435 (rank : 697)
Query Neighborhood Hits	270	Target Neighborhood Hits	74	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UBP4, Q9ULB7	Gene names	DKK3, REIC
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3).

DKK3_MOUSE
θ value	θ > 10 (rank : 369)	NC score	0.064948 (rank : 595)
Query Neighborhood Hits	270	Target Neighborhood Hits	83	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

DMBT1_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.061977 (rank : 617)
Query Neighborhood Hits	270	Target Neighborhood Hits	152	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

DMBT1_MOUSE
θ value	θ > 10 (rank : 371)	NC score	0.075297 (rank : 543)
Query Neighborhood Hits	270	Target Neighborhood Hits	134	Shared Neighborhood Hits	27
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

EGFB2_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.051659 (rank : 718)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	28
SwissProt Accessions	P36368, P00754	Gene names	Egfbp2, Egfbp-2, Klk-13, Klk13
Domain Architecture
Description	Epidermal growth factor-binding protein type B precursor (EC 3.4.21.35) (EGF-BP B) (Glandular kallikrein K13) (Tissue kallikrein 13) (mGK-13) (Prorenin-converting enzyme) (PRECE).

ELA1_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.057017 (rank : 665)
Query Neighborhood Hits	270	Target Neighborhood Hits	178	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UNI1, Q5MLF0, Q6DJT0, Q6ISM6	Gene names	ELA1
Domain Architecture
Description	Elastase-1 precursor (EC 3.4.21.36).

ELA2A_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.059976 (rank : 642)
Query Neighborhood Hits	270	Target Neighborhood Hits	180	Shared Neighborhood Hits	29
SwissProt Accessions	P08217, Q14243	Gene names	ELA2A
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71).

ELA2A_MOUSE
θ value	θ > 10 (rank : 375)	NC score	0.059936 (rank : 643)
Query Neighborhood Hits	270	Target Neighborhood Hits	178	Shared Neighborhood Hits	28
SwissProt Accessions	P05208	Gene names	Ela2a, Ela-2, Ela2
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71) (Elastase-2).

ELA2B_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.059640 (rank : 645)
Query Neighborhood Hits	270	Target Neighborhood Hits	178	Shared Neighborhood Hits	28
SwissProt Accessions	P08218	Gene names	ELA2B
Domain Architecture
Description	Elastase-2B precursor (EC 3.4.21.71).

ELA3A_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.053569 (rank : 696)
Query Neighborhood Hits	270	Target Neighborhood Hits	173	Shared Neighborhood Hits	27
SwissProt Accessions	P09093, Q9BRW4	Gene names	ELA3A, ELA3
Domain Architecture
Description	Elastase-3A precursor (EC 3.4.21.70) (Elastase IIIA) (Protease E).

ELA3B_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.052414 (rank : 708)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	27
SwissProt Accessions	P08861, P11423, Q5VU28, Q5VU29, Q5VU30	Gene names	ELA3B
Domain Architecture
Description	Elastase-3B precursor (EC 3.4.21.70) (Elastase IIIB) (Protease E).

ELTD1_MOUSE
θ value	θ > 10 (rank : 379)	NC score	0.471084 (rank : 140)
Query Neighborhood Hits	270	Target Neighborhood Hits	288	Shared Neighborhood Hits	181
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

EMR4_MOUSE
θ value	θ > 10 (rank : 380)	NC score	0.211564 (rank : 313)
Query Neighborhood Hits	270	Target Neighborhood Hits	191	Shared Neighborhood Hits	111
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

ENTK_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.089036 (rank : 487)
Query Neighborhood Hits	270	Target Neighborhood Hits	310	Shared Neighborhood Hits	61
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

ENTK_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.094503 (rank : 465)
Query Neighborhood Hits	270	Target Neighborhood Hits	338	Shared Neighborhood Hits	65
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

EPGN_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.081435 (rank : 522)
Query Neighborhood Hits	270	Target Neighborhood Hits	59	Shared Neighborhood Hits	33
SwissProt Accessions	Q6UW88	Gene names	EPGN
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

EPGN_MOUSE
θ value	θ > 10 (rank : 384)	NC score	0.091982 (rank : 475)
Query Neighborhood Hits	270	Target Neighborhood Hits	63	Shared Neighborhood Hits	37
SwissProt Accessions	Q924X1, Q8CEX5	Gene names	Epgn
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

EREG_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.121212 (rank : 420)
Query Neighborhood Hits	270	Target Neighborhood Hits	73	Shared Neighborhood Hits	44
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

EREG_MOUSE
θ value	θ > 10 (rank : 386)	NC score	0.072675 (rank : 552)
Query Neighborhood Hits	270	Target Neighborhood Hits	65	Shared Neighborhood Hits	33
SwissProt Accessions	Q61521, Q7M0A8	Gene names	Ereg
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

ESM1_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.116639 (rank : 426)
Query Neighborhood Hits	270	Target Neighborhood Hits	110	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

ESM1_MOUSE
θ value	θ > 10 (rank : 388)	NC score	0.085809 (rank : 504)
Query Neighborhood Hits	270	Target Neighborhood Hits	107	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

FA11_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.065789 (rank : 587)
Query Neighborhood Hits	270	Target Neighborhood Hits	178	Shared Neighborhood Hits	28
SwissProt Accessions	P03951, Q9Y495	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

FA11_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.064303 (rank : 601)
Query Neighborhood Hits	270	Target Neighborhood Hits	180	Shared Neighborhood Hits	27
SwissProt Accessions	Q91Y47	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

FRAS1_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.251731 (rank : 276)
Query Neighborhood Hits	270	Target Neighborhood Hits	759	Shared Neighborhood Hits	158
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FRAS1_MOUSE
θ value	θ > 10 (rank : 392)	NC score	0.238336 (rank : 286)
Query Neighborhood Hits	270	Target Neighborhood Hits	747	Shared Neighborhood Hits	155
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FSTL3_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.111800 (rank : 431)
Query Neighborhood Hits	270	Target Neighborhood Hits	162	Shared Neighborhood Hits	63
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL3_MOUSE
θ value	θ > 10 (rank : 394)	NC score	0.106749 (rank : 439)
Query Neighborhood Hits	270	Target Neighborhood Hits	152	Shared Neighborhood Hits	60
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FST_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.081992 (rank : 519)
Query Neighborhood Hits	270	Target Neighborhood Hits	129	Shared Neighborhood Hits	36
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FST_MOUSE
θ value	θ > 10 (rank : 396)	NC score	0.090473 (rank : 484)
Query Neighborhood Hits	270	Target Neighborhood Hits	146	Shared Neighborhood Hits	46
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

GNPTA_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.066935 (rank : 577)
Query Neighborhood Hits	270	Target Neighborhood Hits	43	Shared Neighborhood Hits	10
SwissProt Accessions	Q3T906, Q3ZQK2, Q6IPW5, Q86TQ2, Q96N13, Q9ULL2	Gene names	GNPTAB, GNPTA, KIAA1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

GNPTA_MOUSE
θ value	θ > 10 (rank : 398)	NC score	0.064762 (rank : 597)
Query Neighborhood Hits	270	Target Neighborhood Hits	47	Shared Neighborhood Hits	9
SwissProt Accessions	Q69ZN6, Q3U3K6, Q3US34	Gene names	Gnptab, Gnpta, Kiaa1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

GP113_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.060942 (rank : 625)
Query Neighborhood Hits	270	Target Neighborhood Hits	102	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IZF5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3	Gene names	GPR113, PGR23
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 113 precursor (G-protein coupled receptor PGR23).

GP114_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.050217 (rank : 732)
Query Neighborhood Hits	270	Target Neighborhood Hits	75	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IZF4, Q6ZMH7, Q6ZML4, Q86SL8, Q8IZ14	Gene names	GPR114, PGR27
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 114 precursor (G-protein coupled receptor PGR27).

GP116_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.050580 (rank : 728)
Query Neighborhood Hits	270	Target Neighborhood Hits	167	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

GP124_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.054139 (rank : 689)
Query Neighborhood Hits	270	Target Neighborhood Hits	304	Shared Neighborhood Hits	20
SwissProt Accessions	Q96PE1, Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4	Gene names	GPR124, KIAA1531, TEM5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GP124_MOUSE
θ value	θ > 10 (rank : 403)	NC score	0.055992 (rank : 671)
Query Neighborhood Hits	270	Target Neighborhood Hits	423	Shared Neighborhood Hits	25
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GP125_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.057572 (rank : 662)
Query Neighborhood Hits	270	Target Neighborhood Hits	327	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

GP125_MOUSE
θ value	θ > 10 (rank : 405)	NC score	0.054249 (rank : 688)
Query Neighborhood Hits	270	Target Neighborhood Hits	329	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

GP126_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.091127 (rank : 480)
Query Neighborhood Hits	270	Target Neighborhood Hits	187	Shared Neighborhood Hits	35
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

GP128_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.070722 (rank : 561)
Query Neighborhood Hits	270	Target Neighborhood Hits	135	Shared Neighborhood Hits	43
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

GP128_MOUSE
θ value	θ > 10 (rank : 408)	NC score	0.071864 (rank : 554)
Query Neighborhood Hits	270	Target Neighborhood Hits	141	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BM96, Q80T42	Gene names	Gpr128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

GP133_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.054791 (rank : 682)
Query Neighborhood Hits	270	Target Neighborhood Hits	115	Shared Neighborhood Hits	13
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

GP144_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.055680 (rank : 675)
Query Neighborhood Hits	270	Target Neighborhood Hits	108	Shared Neighborhood Hits	15
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

GPR64_MOUSE
θ value	θ > 10 (rank : 411)	NC score	0.051173 (rank : 725)
Query Neighborhood Hits	270	Target Neighborhood Hits	156	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

GRAC_MOUSE
θ value	θ > 10 (rank : 412)	NC score	0.053347 (rank : 698)
Query Neighborhood Hits	270	Target Neighborhood Hits	177	Shared Neighborhood Hits	28
SwissProt Accessions	P08882, Q61389	Gene names	Gzmc, Ctla-5, Ctla5
Domain Architecture
Description	Granzyme C precursor (EC 3.4.21.-) (Cytotoxic cell protease 2) (CCP2) (B10).

GRAD_MOUSE
θ value	θ > 10 (rank : 413)	NC score	0.054703 (rank : 683)
Query Neighborhood Hits	270	Target Neighborhood Hits	173	Shared Neighborhood Hits	28
SwissProt Accessions	P11033, P97387	Gene names	Gzmd
Domain Architecture
Description	Granzyme D precursor (EC 3.4.21.-).

GRAE_MOUSE
θ value	θ > 10 (rank : 414)	NC score	0.054074 (rank : 690)
Query Neighborhood Hits	270	Target Neighborhood Hits	172	Shared Neighborhood Hits	28
SwissProt Accessions	P08884, P97389	Gene names	Gzme, Ccp3, Ctla-6, Ctla6
Domain Architecture
Description	Granzyme E precursor (EC 3.4.21.-) (Cytotoxic cell protease 3) (CCP3) (CTL serine protease 2) (D12) (Cytotoxic serine protease 2) (MCSP2).

GRAF_MOUSE
θ value	θ > 10 (rank : 415)	NC score	0.052174 (rank : 713)
Query Neighborhood Hits	270	Target Neighborhood Hits	172	Shared Neighborhood Hits	28
SwissProt Accessions	P08883	Gene names	Gzmf, Ccp4, Ctla-7, Ctla7
Domain Architecture
Description	Granzyme F precursor (EC 3.4.21.-) (Cytotoxic cell protease 4) (CCP4) (CTL serine protease 3) (C134) (Cytotoxic serine protease 3) (MCSP3).

GRAG_MOUSE
θ value	θ > 10 (rank : 416)	NC score	0.054018 (rank : 691)
Query Neighborhood Hits	270	Target Neighborhood Hits	173	Shared Neighborhood Hits	28
SwissProt Accessions	P13366, P97388	Gene names	Gzmg
Domain Architecture
Description	Granzyme G precursor (EC 3.4.21.-) (CTL serine protease 1) (MCSP-1).

GRAH_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.056459 (rank : 667)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	P20718	Gene names	GZMH, CGL2, CTSGL2
Domain Architecture
Description	Granzyme H precursor (EC 3.4.21.-) (Cytotoxic T-lymphocyte proteinase) (Cathepsin G-like 2) (CTSGL2) (CCP-X) (Cytotoxic serine protease C) (CSP-C).

GRAK_MOUSE
θ value	θ > 10 (rank : 418)	NC score	0.053743 (rank : 693)
Query Neighborhood Hits	270	Target Neighborhood Hits	174	Shared Neighborhood Hits	27
SwissProt Accessions	O35205	Gene names	Gzmk
Domain Architecture
Description	Granzyme K precursor (EC 3.4.21.-).

GRAM_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.055825 (rank : 672)
Query Neighborhood Hits	270	Target Neighborhood Hits	174	Shared Neighborhood Hits	28
SwissProt Accessions	P51124	Gene names	GZMM, MET1
Domain Architecture
Description	Granzyme M precursor (EC 3.4.21.-) (Met-ase) (Natural killer cell granular protease) (HU-Met-1) (Met-1 serine protease).

GRN_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.387131 (rank : 157)
Query Neighborhood Hits	270	Target Neighborhood Hits	268	Shared Neighborhood Hits	130
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

HBEGF_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.065852 (rank : 586)
Query Neighborhood Hits	270	Target Neighborhood Hits	61	Shared Neighborhood Hits	35
SwissProt Accessions	Q99075	Gene names	HBEGF, DTR, HEGFL
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF) (Diphtheria toxin receptor) (DT-R).

HEPS_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.065902 (rank : 584)
Query Neighborhood Hits	270	Target Neighborhood Hits	178	Shared Neighborhood Hits	29
SwissProt Accessions	P05981	Gene names	HPN, TMPRSS1
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) (Transmembrane protease, serine 1) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

HEPS_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.065359 (rank : 589)
Query Neighborhood Hits	270	Target Neighborhood Hits	178	Shared Neighborhood Hits	29
SwissProt Accessions	O35453, Q9CW97	Gene names	Hpn
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

HGFL_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.058401 (rank : 656)
Query Neighborhood Hits	270	Target Neighborhood Hits	190	Shared Neighborhood Hits	32
SwissProt Accessions	P26927, Q13350, Q14870	Gene names	MST1, HGFL
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) (Macrophage-stimulating protein) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

HGFL_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.057879 (rank : 660)
Query Neighborhood Hits	270	Target Neighborhood Hits	188	Shared Neighborhood Hits	30
SwissProt Accessions	P26928	Gene names	Mst1, Hgfl
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

HPLN1_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.079824 (rank : 527)
Query Neighborhood Hits	270	Target Neighborhood Hits	67	Shared Neighborhood Hits	11
SwissProt Accessions	P10915	Gene names	HAPLN1, CRTL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

HPLN1_MOUSE
θ value	θ > 10 (rank : 427)	NC score	0.079697 (rank : 529)
Query Neighborhood Hits	270	Target Neighborhood Hits	64	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QUP5, Q9D1G9, Q9Z1X7	Gene names	Hapln1, Crtl1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

HPLN2_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.082033 (rank : 518)
Query Neighborhood Hits	270	Target Neighborhood Hits	80	Shared Neighborhood Hits	13
SwissProt Accessions	Q9GZV7	Gene names	HAPLN2, BRAL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

HPLN2_MOUSE
θ value	θ > 10 (rank : 429)	NC score	0.082508 (rank : 516)
Query Neighborhood Hits	270	Target Neighborhood Hits	102	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ESM3	Gene names	Hapln2, Bral1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

HPLN3_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.081423 (rank : 523)
Query Neighborhood Hits	270	Target Neighborhood Hits	70	Shared Neighborhood Hits	11
SwissProt Accessions	Q96S86	Gene names	HAPLN3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor.

HPLN3_MOUSE
θ value	θ > 10 (rank : 431)	NC score	0.082520 (rank : 515)
Query Neighborhood Hits	270	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	Q80WM5, Q80XX3	Gene names	Hapln3, Lpr3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor (Link protein 3).

HPLN4_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.079808 (rank : 528)
Query Neighborhood Hits	270	Target Neighborhood Hits	100	Shared Neighborhood Hits	12
SwissProt Accessions	Q86UW8, Q96PW2	Gene names	HAPLN4, BRAL2, KIAA1926
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2).

HPLN4_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.079141 (rank : 530)
Query Neighborhood Hits	270	Target Neighborhood Hits	98	Shared Neighborhood Hits	13
SwissProt Accessions	Q80WM4, Q80XX2	Gene names	Hapln4, Bral2, Lpr4
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2) (Link protein 4).

HPTR_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.086496 (rank : 498)
Query Neighborhood Hits	270	Target Neighborhood Hits	166	Shared Neighborhood Hits	28
SwissProt Accessions	P00739, Q7LE20, Q92658, Q92659, Q9ULB0	Gene names	HPR
Domain Architecture
Description	Haptoglobin-related protein precursor.

HPT_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.088136 (rank : 492)
Query Neighborhood Hits	270	Target Neighborhood Hits	184	Shared Neighborhood Hits	29
SwissProt Accessions	P00738, P00737, Q2PP15, Q3B7J0, Q6LBY9	Gene names	HP
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

HPT_MOUSE
θ value	θ > 10 (rank : 436)	NC score	0.085340 (rank : 505)
Query Neighborhood Hits	270	Target Neighborhood Hits	178	Shared Neighborhood Hits	28
SwissProt Accessions	Q61646	Gene names	Hp
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

IDD_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.078702 (rank : 532)
Query Neighborhood Hits	270	Target Neighborhood Hits	127	Shared Neighborhood Hits	32
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

IDD_MOUSE
θ value	θ > 10 (rank : 438)	NC score	0.077458 (rank : 537)
Query Neighborhood Hits	270	Target Neighborhood Hits	151	Shared Neighborhood Hits	31
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

ITB1_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.262726 (rank : 271)
Query Neighborhood Hits	270	Target Neighborhood Hits	298	Shared Neighborhood Hits	148
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB1_MOUSE
θ value	θ > 10 (rank : 440)	NC score	0.270614 (rank : 267)
Query Neighborhood Hits	270	Target Neighborhood Hits	283	Shared Neighborhood Hits	149
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB2_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.281624 (rank : 261)
Query Neighborhood Hits	270	Target Neighborhood Hits	282	Shared Neighborhood Hits	161
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB2_MOUSE
θ value	θ > 10 (rank : 442)	NC score	0.284902 (rank : 256)
Query Neighborhood Hits	270	Target Neighborhood Hits	326	Shared Neighborhood Hits	172
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB5_HUMAN
θ value	θ > 10 (rank : 443)	NC score	0.296597 (rank : 233)
Query Neighborhood Hits	270	Target Neighborhood Hits	310	Shared Neighborhood Hits	174
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB5_MOUSE
θ value	θ > 10 (rank : 444)	NC score	0.312138 (rank : 217)
Query Neighborhood Hits	270	Target Neighborhood Hits	329	Shared Neighborhood Hits	182
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB6_HUMAN
θ value	θ > 10 (rank : 445)	NC score	0.304857 (rank : 226)
Query Neighborhood Hits	270	Target Neighborhood Hits	318	Shared Neighborhood Hits	164
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB7_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.288603 (rank : 249)
Query Neighborhood Hits	270	Target Neighborhood Hits	290	Shared Neighborhood Hits	169
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

ITB7_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.285483 (rank : 254)
Query Neighborhood Hits	270	Target Neighborhood Hits	277	Shared Neighborhood Hits	168
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

K1B11_MOUSE
θ value	θ > 10 (rank : 448)	NC score	0.054935 (rank : 681)
Query Neighborhood Hits	270	Target Neighborhood Hits	180	Shared Neighborhood Hits	28
SwissProt Accessions	P15946	Gene names	Klk1b11, Klk-11, Klk11
Domain Architecture
Description	Kallikrein 1-related peptidase b11 precursor (EC 3.4.21.35) (Tissue kallikrein-11) (Glandular kallikrein K11) (mGK-11).

K1B21_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.052844 (rank : 706)
Query Neighborhood Hits	270	Target Neighborhood Hits	179	Shared Neighborhood Hits	28
SwissProt Accessions	Q61759, Q61760, Q9JM70	Gene names	Klk1b21, Klk-21, Klk21
Domain Architecture
Description	Kallikrein 1-related peptidase b21 precursor (EC 3.4.21.35) (Tissue kallikrein 21) (Glandular kallikrein K21) (mGK-21).

K1B22_MOUSE
θ value	θ > 10 (rank : 450)	NC score	0.052942 (rank : 705)
Query Neighborhood Hits	270	Target Neighborhood Hits	174	Shared Neighborhood Hits	28
SwissProt Accessions	P15948	Gene names	Klk1b22, Klk-22, Klk22
Domain Architecture
Description	Kallikrein 1-related peptidase b22 precursor (EC 3.4.21.35) (Glandular kallikrein K22) (Tissue kallikrein 22) (mGK-22) (Epidermal growth factor-binding protein type A) (EGF-BP A) (Nerve growth factor beta chain endopeptidase) (Beta-NGF-endopeptidase).

K1B24_MOUSE
θ value	θ > 10 (rank : 451)	NC score	0.052273 (rank : 712)
Query Neighborhood Hits	270	Target Neighborhood Hits	180	Shared Neighborhood Hits	28
SwissProt Accessions	Q61754, Q61755, Q9JM69	Gene names	Klk1b24, Klk-24, Klk24
Domain Architecture
Description	Kallikrein 1-related peptidase b24 precursor (EC 3.4.21.35) (Glandular kallikrein K24) (Tissue kallikrein 24) (mGK-24).

K1B26_MOUSE
θ value	θ > 10 (rank : 452)	NC score	0.052065 (rank : 715)
Query Neighborhood Hits	270	Target Neighborhood Hits	177	Shared Neighborhood Hits	28
SwissProt Accessions	P36369, P00753, P00754	Gene names	Klk1b26, Klk-26, Klk26
Domain Architecture
Description	Kallikrein 1-related peptidase b26 precursor (EC 3.4.21.35) (Glandular kallikrein K26) (Tissue kallikrein 26) (mGK-26) (Prorenin-converting enzyme 2) (PRECE-2).

K1B27_MOUSE
θ value	θ > 10 (rank : 453)	NC score	0.052026 (rank : 716)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JM71	Gene names	Klk1b27, Klk-27, Klk27
Domain Architecture
Description	Kallikrein 1-related peptidase b27 precursor (EC 3.4.21.-) (Tissue kallikrein 27) (Glandular kallikrein K27) (mGK-27) (mKlk27).

K1KB1_MOUSE
θ value	θ > 10 (rank : 454)	NC score	0.053882 (rank : 692)
Query Neighborhood Hits	270	Target Neighborhood Hits	180	Shared Neighborhood Hits	28
SwissProt Accessions	P00755	Gene names	Klk1b1, Klk-1, Klk1
Domain Architecture
Description	Kallikrein 1-related peptidase b1 precursor (EC 3.4.21.35) (Glandular kallikrein K1) (Tissue kallikrein-1) (mGK-1).

K1KB3_MOUSE
θ value	θ > 10 (rank : 455)	NC score	0.054380 (rank : 686)
Query Neighborhood Hits	270	Target Neighborhood Hits	179	Shared Neighborhood Hits	28
SwissProt Accessions	P00756	Gene names	Klk1b3, Klk-3, Klk3, Ngfg
Domain Architecture
Description	Kallikrein 1-related peptidase b3 precursor (EC 3.4.21.35) (Glandular kallikrein K3) (Tissue kallikrein-3) (mGK-3) (7S nerve growth factor gamma chain) (Gamma-NGF) [Contains: Nerve growth factor gamma chain 1; Nerve growth factor gamma chain 2].

K1KB4_MOUSE
θ value	θ > 10 (rank : 456)	NC score	0.053146 (rank : 702)
Query Neighborhood Hits	270	Target Neighborhood Hits	177	Shared Neighborhood Hits	28
SwissProt Accessions	P00757	Gene names	Klk1b4, Klk-4, Klk4, Ngfa
Domain Architecture
Description	Kallikrein 1-related peptidase-like b4 precursor (7S nerve growth factor alpha chain) (Alpha-NGF).

K1KB5_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.053247 (rank : 700)
Query Neighborhood Hits	270	Target Neighborhood Hits	177	Shared Neighborhood Hits	28
SwissProt Accessions	P15945, Q52KM1, Q565D7	Gene names	Klk1b5, Klk-5, Klk5
Domain Architecture
Description	Kallikrein 1-related peptidase b5 precursor (EC 3.4.21.35) (Glandular kallikrein K5) (Tissue kallikrein-5) (mGK-5).

K1KB8_MOUSE
θ value	θ > 10 (rank : 458)	NC score	0.051456 (rank : 721)
Query Neighborhood Hits	270	Target Neighborhood Hits	177	Shared Neighborhood Hits	28
SwissProt Accessions	P07628	Gene names	Klk1b8, Klk-8, Klk8
Domain Architecture
Description	Kallikrein 1-related peptidase b8 precursor (EC 3.4.21.35) (Tissue kallikrein-8) (Glandular kallikrein K8) (mGK-8).

K1KB9_MOUSE
θ value	θ > 10 (rank : 459)	NC score	0.056663 (rank : 666)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	28
SwissProt Accessions	P15949	Gene names	Klk1b9, Egfbp3, Klk-9, Klk9
Domain Architecture
Description	Kallikrein 1-related peptidase b9 precursor (EC 3.4.21.35) (Tissue kallikrein-9) (Glandular kallikrein K9) (mGK-9) (Epidermal growth factor-binding protein type C) (EGF-BP C).

KLK10_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.060592 (rank : 631)
Query Neighborhood Hits	270	Target Neighborhood Hits	178	Shared Neighborhood Hits	28
SwissProt Accessions	O43240, Q99920, Q9GZW9	Gene names	KLK10, NES1, PRRSL1
Domain Architecture
Description	Kallikrein-10 precursor (EC 3.4.21.-) (Protease serine-like 1) (Normal epithelial cell-specific 1).

KLK11_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.057373 (rank : 664)
Query Neighborhood Hits	270	Target Neighborhood Hits	174	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UBX7, O75837, Q9NS65	Gene names	KLK11, PRSS20, TLSP
Domain Architecture
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin) (Trypsin-like protease).

KLK11_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.058710 (rank : 654)
Query Neighborhood Hits	270	Target Neighborhood Hits	174	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QYN3, Q9QYN4	Gene names	Klk11, Prss20
Domain Architecture	No domain graphic available
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin).

KLK12_HUMAN
θ value	θ > 10 (rank : 463)	NC score	0.060418 (rank : 634)
Query Neighborhood Hits	270	Target Neighborhood Hits	197	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UKR0, Q9UKR1	Gene names	KLK12, KLKL5
Domain Architecture
Description	Kallikrein-12 precursor (EC 3.4.21.-) (Kallikrein-like protein 5) (KLK-L5).

KLK13_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.062246 (rank : 614)
Query Neighborhood Hits	270	Target Neighborhood Hits	179	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UKR3, Q9Y433	Gene names	KLK13, KLKL4
Domain Architecture
Description	Kallikrein-13 precursor (EC 3.4.21.-) (Kallikrein-like protein 4) (KLK-L4).

KLK14_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.062842 (rank : 611)
Query Neighborhood Hits	270	Target Neighborhood Hits	179	Shared Neighborhood Hits	28
SwissProt Accessions	Q9P0G3	Gene names	KLK14, KLKL6
Domain Architecture
Description	Kallikrein-14 precursor (EC 3.4.21.-) (Kallikrein-like protein 6) (KLK-L6).

KLK15_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.060520 (rank : 632)
Query Neighborhood Hits	270	Target Neighborhood Hits	180	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H2R5, Q15358, Q9H2R3, Q9H2R4, Q9H2R6, Q9HBG9	Gene names	KLK15
Domain Architecture
Description	Kallikrein-15 precursor (EC 3.4.21.-) (ACO protease).

KLK1_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.050275 (rank : 731)
Query Neighborhood Hits	270	Target Neighborhood Hits	183	Shared Neighborhood Hits	27
SwissProt Accessions	P06870, Q8TCV8, Q9BS53, Q9NQU4, Q9UMJ1	Gene names	KLK1
Domain Architecture
Description	Kallikrein-1 precursor (EC 3.4.21.35) (Tissue kallikrein) (Kidney/pancreas/salivary gland kallikrein).

KLK1_MOUSE
θ value	θ > 10 (rank : 468)	NC score	0.054641 (rank : 684)
Query Neighborhood Hits	270	Target Neighborhood Hits	179	Shared Neighborhood Hits	28
SwissProt Accessions	P15947, Q61855	Gene names	Klk1, Klk-6, Klk6
Domain Architecture
Description	Glandular kallikrein K1 precursor (EC 3.4.21.35) (Tissue kallikrein-6) (mGK-6) (Renal kallikrein) (KAL-B).

KLK2_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.054454 (rank : 685)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	28
SwissProt Accessions	P20151, Q15946, Q9UJZ9	Gene names	KLK2
Domain Architecture
Description	Kallikrein-2 precursor (EC 3.4.21.35) (Tissue kallikrein-2) (Glandular kallikrein-1) (hGK-1).

KLK3_HUMAN
θ value	θ > 10 (rank : 470)	NC score	0.055763 (rank : 674)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	28
SwissProt Accessions	P07288, Q16272, Q86TG8	Gene names	KLK3, APS
Domain Architecture
Description	Prostate-specific antigen precursor (EC 3.4.21.77) (PSA) (Kallikrein- 3) (Semenogelase) (Gamma-seminoprotein) (Seminin) (P-30 antigen).

KLK4_HUMAN
θ value	θ > 10 (rank : 471)	NC score	0.058421 (rank : 655)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y5K2, Q4VB16, Q9GZL6, Q9UBJ6	Gene names	KLK4, EMSP1, PRSS17, PSTS
Domain Architecture
Description	Kallikrein-4 precursor (EC 3.4.21.-) (Prostase) (Kallikrein-like protein 1) (KLK-L1) (Enamel matrix serine proteinase 1).

KLK5_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.058125 (rank : 658)
Query Neighborhood Hits	270	Target Neighborhood Hits	182	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y337, Q9HBG8	Gene names	KLK5, SCTE
Domain Architecture
Description	Kallikrein-5 precursor (EC 3.4.21.-) (Stratum corneum tryptic enzyme) (Kallikrein-like protein 2) (KLK-L2).

KLK6_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.062842 (rank : 612)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	Q92876	Gene names	KLK6, PRSS18, PRSS9
Domain Architecture
Description	Kallikrein-6 precursor (EC 3.4.21.-) (Protease M) (Neurosin) (Zyme) (SP59).

KLK7_HUMAN
θ value	θ > 10 (rank : 474)	NC score	0.060000 (rank : 640)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	P49862, Q8N5N9, Q8NFV7	Gene names	KLK7, PRSS6, SCCE
Domain Architecture
Description	Kallikrein-7 precursor (EC 3.4.21.-) (hK7) (Stratum corneum chymotryptic enzyme) (hSCCE).

KLK7_MOUSE
θ value	θ > 10 (rank : 475)	NC score	0.061617 (rank : 620)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	Q91VE3, Q9R048	Gene names	Klk7, Prss6, Scce
Domain Architecture	No domain graphic available
Description	Kallikrein-7 precursor (EC 3.4.21.-) (Stratum corneum chymotryptic enzyme) (Thymopsin).

KLK9_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.056415 (rank : 668)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UKQ9	Gene names	KLK9
Domain Architecture
Description	Kallikrein-9 precursor (EC 3.4.21.-) (Kallikrein-like protein 3) (KLK- L3).

KLKB1_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.067480 (rank : 574)
Query Neighborhood Hits	270	Target Neighborhood Hits	183	Shared Neighborhood Hits	29
SwissProt Accessions	P03952	Gene names	KLKB1, KLK3
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

KLKB1_MOUSE
θ value	θ > 10 (rank : 478)	NC score	0.066957 (rank : 576)
Query Neighborhood Hits	270	Target Neighborhood Hits	177	Shared Neighborhood Hits	28
SwissProt Accessions	P26262	Gene names	Klkb1, Klk3, Pk
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

KR101_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.301234 (rank : 230)
Query Neighborhood Hits	270	Target Neighborhood Hits	261	Shared Neighborhood Hits	103
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR102_HUMAN
θ value	θ > 10 (rank : 480)	NC score	0.284427 (rank : 257)
Query Neighborhood Hits	270	Target Neighborhood Hits	264	Shared Neighborhood Hits	103
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR103_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.173989 (rank : 354)
Query Neighborhood Hits	270	Target Neighborhood Hits	212	Shared Neighborhood Hits	76
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

KR104_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.355914 (rank : 170)
Query Neighborhood Hits	270	Target Neighborhood Hits	313	Shared Neighborhood Hits	126
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR105_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.275173 (rank : 266)
Query Neighborhood Hits	270	Target Neighborhood Hits	271	Shared Neighborhood Hits	107
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR106_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.360017 (rank : 169)
Query Neighborhood Hits	270	Target Neighborhood Hits	347	Shared Neighborhood Hits	138
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR107_HUMAN
θ value	θ > 10 (rank : 485)	NC score	0.368320 (rank : 164)
Query Neighborhood Hits	270	Target Neighborhood Hits	330	Shared Neighborhood Hits	136
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR108_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.239180 (rank : 285)
Query Neighborhood Hits	270	Target Neighborhood Hits	226	Shared Neighborhood Hits	86
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR109_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.243600 (rank : 283)
Query Neighborhood Hits	270	Target Neighborhood Hits	226	Shared Neighborhood Hits	92
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR10A_HUMAN
θ value	θ > 10 (rank : 488)	NC score	0.183375 (rank : 341)
Query Neighborhood Hits	270	Target Neighborhood Hits	232	Shared Neighborhood Hits	87
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

KR10B_HUMAN
θ value	θ > 10 (rank : 489)	NC score	0.222992 (rank : 298)
Query Neighborhood Hits	270	Target Neighborhood Hits	269	Shared Neighborhood Hits	97
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KR10C_HUMAN
θ value	θ > 10 (rank : 490)	NC score	0.230986 (rank : 294)
Query Neighborhood Hits	270	Target Neighborhood Hits	219	Shared Neighborhood Hits	88
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KR171_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.291185 (rank : 240)
Query Neighborhood Hits	270	Target Neighborhood Hits	144	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KR221_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.051577 (rank : 719)
Query Neighborhood Hits	270	Target Neighborhood Hits	6	Shared Neighborhood Hits	5
SwissProt Accessions	Q3MIV0	Gene names	KRTAP22-1, KAP22.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 22-1.

KR410_HUMAN
θ value	θ > 10 (rank : 493)	NC score	0.125752 (rank : 412)
Query Neighborhood Hits	270	Target Neighborhood Hits	156	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

KR412_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.175158 (rank : 352)
Query Neighborhood Hits	270	Target Neighborhood Hits	178	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR413_HUMAN
θ value	θ > 10 (rank : 495)	NC score	0.111490 (rank : 432)
Query Neighborhood Hits	270	Target Neighborhood Hits	112	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

KR414_HUMAN
θ value	θ > 10 (rank : 496)	NC score	0.189863 (rank : 336)
Query Neighborhood Hits	270	Target Neighborhood Hits	199	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KR510_HUMAN
θ value	θ > 10 (rank : 497)	NC score	0.212848 (rank : 311)
Query Neighborhood Hits	270	Target Neighborhood Hits	217	Shared Neighborhood Hits	80
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KR511_HUMAN
θ value	θ > 10 (rank : 498)	NC score	0.286627 (rank : 253)
Query Neighborhood Hits	270	Target Neighborhood Hits	231	Shared Neighborhood Hits	91
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA11_HUMAN
θ value	θ > 10 (rank : 499)	NC score	0.194064 (rank : 332)
Query Neighborhood Hits	270	Target Neighborhood Hits	155	Shared Neighborhood Hits	64
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

KRA13_HUMAN
θ value	θ > 10 (rank : 500)	NC score	0.217128 (rank : 305)
Query Neighborhood Hits	270	Target Neighborhood Hits	144	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

KRA15_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.188282 (rank : 337)
Query Neighborhood Hits	270	Target Neighborhood Hits	126	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KRA24_HUMAN
θ value	θ > 10 (rank : 502)	NC score	0.068248 (rank : 568)
Query Neighborhood Hits	270	Target Neighborhood Hits	192	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

KRA42_HUMAN
θ value	θ > 10 (rank : 503)	NC score	0.117812 (rank : 425)
Query Neighborhood Hits	270	Target Neighborhood Hits	149	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

KRA44_HUMAN
θ value	θ > 10 (rank : 504)	NC score	0.206864 (rank : 317)
Query Neighborhood Hits	270	Target Neighborhood Hits	162	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KRA45_HUMAN
θ value	θ > 10 (rank : 505)	NC score	0.203669 (rank : 322)
Query Neighborhood Hits	270	Target Neighborhood Hits	194	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

KRA47_HUMAN
θ value	θ > 10 (rank : 506)	NC score	0.190494 (rank : 334)
Query Neighborhood Hits	270	Target Neighborhood Hits	204	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KRA52_HUMAN
θ value	θ > 10 (rank : 507)	NC score	0.246096 (rank : 282)
Query Neighborhood Hits	270	Target Neighborhood Hits	236	Shared Neighborhood Hits	94
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KRA54_HUMAN
θ value	θ > 10 (rank : 508)	NC score	0.302764 (rank : 228)
Query Neighborhood Hits	270	Target Neighborhood Hits	270	Shared Neighborhood Hits	106
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA55_HUMAN
θ value	θ > 10 (rank : 509)	NC score	0.302004 (rank : 229)
Query Neighborhood Hits	270	Target Neighborhood Hits	257	Shared Neighborhood Hits	104
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA59_HUMAN
θ value	θ > 10 (rank : 510)	NC score	0.316351 (rank : 214)
Query Neighborhood Hits	270	Target Neighborhood Hits	310	Shared Neighborhood Hits	115
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KRA92_HUMAN
θ value	θ > 10 (rank : 511)	NC score	0.200968 (rank : 327)
Query Neighborhood Hits	270	Target Neighborhood Hits	198	Shared Neighborhood Hits	74
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA93_HUMAN
θ value	θ > 10 (rank : 512)	NC score	0.225878 (rank : 296)
Query Neighborhood Hits	270	Target Neighborhood Hits	203	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA94_HUMAN
θ value	θ > 10 (rank : 513)	NC score	0.231175 (rank : 293)
Query Neighborhood Hits	270	Target Neighborhood Hits	204	Shared Neighborhood Hits	82
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KRA98_HUMAN
θ value	θ > 10 (rank : 514)	NC score	0.226032 (rank : 295)
Query Neighborhood Hits	270	Target Neighborhood Hits	185	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA99_HUMAN
θ value	θ > 10 (rank : 515)	NC score	0.212362 (rank : 312)
Query Neighborhood Hits	270	Target Neighborhood Hits	173	Shared Neighborhood Hits	73
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

KREM1_HUMAN
θ value	θ > 10 (rank : 516)	NC score	0.064035 (rank : 604)
Query Neighborhood Hits	270	Target Neighborhood Hits	90	Shared Neighborhood Hits	31
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM1_MOUSE
θ value	θ > 10 (rank : 517)	NC score	0.066414 (rank : 582)
Query Neighborhood Hits	270	Target Neighborhood Hits	92	Shared Neighborhood Hits	33
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM2_HUMAN
θ value	θ > 10 (rank : 518)	NC score	0.065073 (rank : 594)
Query Neighborhood Hits	270	Target Neighborhood Hits	93	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

KREM2_MOUSE
θ value	θ > 10 (rank : 519)	NC score	0.060428 (rank : 633)
Query Neighborhood Hits	270	Target Neighborhood Hits	90	Shared Neighborhood Hits	29
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

LAMA2_HUMAN
θ value	θ > 10 (rank : 520)	NC score	0.316408 (rank : 213)
Query Neighborhood Hits	270	Target Neighborhood Hits	1092	Shared Neighborhood Hits	191
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA3_HUMAN
θ value	θ > 10 (rank : 521)	NC score	0.256484 (rank : 274)
Query Neighborhood Hits	270	Target Neighborhood Hits	760	Shared Neighborhood Hits	174
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

LAMA4_HUMAN
θ value	θ > 10 (rank : 522)	NC score	0.236790 (rank : 288)
Query Neighborhood Hits	270	Target Neighborhood Hits	708	Shared Neighborhood Hits	157
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA4_MOUSE
θ value	θ > 10 (rank : 523)	NC score	0.250658 (rank : 277)
Query Neighborhood Hits	270	Target Neighborhood Hits	584	Shared Neighborhood Hits	155
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA5_HUMAN
θ value	θ > 10 (rank : 524)	NC score	0.360845 (rank : 168)
Query Neighborhood Hits	270	Target Neighborhood Hits	976	Shared Neighborhood Hits	206
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMA5_MOUSE
θ value	θ > 10 (rank : 525)	NC score	0.373058 (rank : 162)
Query Neighborhood Hits	270	Target Neighborhood Hits	828	Shared Neighborhood Hits	209
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB1_HUMAN
θ value	θ > 10 (rank : 526)	NC score	0.294875 (rank : 236)
Query Neighborhood Hits	270	Target Neighborhood Hits	1018	Shared Neighborhood Hits	187
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB1_MOUSE
θ value	θ > 10 (rank : 527)	NC score	0.308882 (rank : 220)
Query Neighborhood Hits	270	Target Neighborhood Hits	919	Shared Neighborhood Hits	189
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB2_HUMAN
θ value	θ > 10 (rank : 528)	NC score	0.352813 (rank : 173)
Query Neighborhood Hits	270	Target Neighborhood Hits	692	Shared Neighborhood Hits	191
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB3_HUMAN
θ value	θ > 10 (rank : 529)	NC score	0.256758 (rank : 273)
Query Neighborhood Hits	270	Target Neighborhood Hits	461	Shared Neighborhood Hits	136
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMB3_MOUSE
θ value	θ > 10 (rank : 530)	NC score	0.288666 (rank : 248)
Query Neighborhood Hits	270	Target Neighborhood Hits	444	Shared Neighborhood Hits	154
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LAMC2_HUMAN
θ value	θ > 10 (rank : 531)	NC score	0.319514 (rank : 206)
Query Neighborhood Hits	270	Target Neighborhood Hits	715	Shared Neighborhood Hits	176
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LAMC2_MOUSE
θ value	θ > 10 (rank : 532)	NC score	0.341971 (rank : 182)
Query Neighborhood Hits	270	Target Neighborhood Hits	614	Shared Neighborhood Hits	193
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LAMC3_HUMAN
θ value	θ > 10 (rank : 533)	NC score	0.325473 (rank : 198)
Query Neighborhood Hits	270	Target Neighborhood Hits	588	Shared Neighborhood Hits	183
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC3_MOUSE
θ value	θ > 10 (rank : 534)	NC score	0.335798 (rank : 189)
Query Neighborhood Hits	270	Target Neighborhood Hits	624	Shared Neighborhood Hits	189
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LCE1A_HUMAN
θ value	θ > 10 (rank : 535)	NC score	0.165346 (rank : 364)
Query Neighborhood Hits	270	Target Neighborhood Hits	47	Shared Neighborhood Hits	21
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LCE1B_HUMAN
θ value	θ > 10 (rank : 536)	NC score	0.234014 (rank : 291)
Query Neighborhood Hits	270	Target Neighborhood Hits	58	Shared Neighborhood Hits	30
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
θ value	θ > 10 (rank : 537)	NC score	0.218304 (rank : 303)
Query Neighborhood Hits	270	Target Neighborhood Hits	65	Shared Neighborhood Hits	30
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1D_HUMAN
θ value	θ > 10 (rank : 538)	NC score	0.204063 (rank : 320)
Query Neighborhood Hits	270	Target Neighborhood Hits	44	Shared Neighborhood Hits	21
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE1E_HUMAN
θ value	θ > 10 (rank : 539)	NC score	0.176795 (rank : 349)
Query Neighborhood Hits	270	Target Neighborhood Hits	53	Shared Neighborhood Hits	21
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LCE1F_HUMAN
θ value	θ > 10 (rank : 540)	NC score	0.158812 (rank : 373)
Query Neighborhood Hits	270	Target Neighborhood Hits	48	Shared Neighborhood Hits	20
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LCE2A_HUMAN
θ value	θ > 10 (rank : 541)	NC score	0.081602 (rank : 521)
Query Neighborhood Hits	270	Target Neighborhood Hits	50	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

LCE2B_HUMAN
θ value	θ > 10 (rank : 542)	NC score	0.083236 (rank : 514)
Query Neighborhood Hits	270	Target Neighborhood Hits	50	Shared Neighborhood Hits	13
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

LCE2C_HUMAN
θ value	θ > 10 (rank : 543)	NC score	0.108569 (rank : 437)
Query Neighborhood Hits	270	Target Neighborhood Hits	53	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LCE2D_HUMAN
θ value	θ > 10 (rank : 544)	NC score	0.091439 (rank : 477)
Query Neighborhood Hits	270	Target Neighborhood Hits	50	Shared Neighborhood Hits	11
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

LCE3A_HUMAN
θ value	θ > 10 (rank : 545)	NC score	0.134878 (rank : 398)
Query Neighborhood Hits	270	Target Neighborhood Hits	29	Shared Neighborhood Hits	17
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

LCE3B_HUMAN
θ value	θ > 10 (rank : 546)	NC score	0.070867 (rank : 560)
Query Neighborhood Hits	270	Target Neighborhood Hits	47	Shared Neighborhood Hits	20
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

LCE4A_HUMAN
θ value	θ > 10 (rank : 547)	NC score	0.101004 (rank : 452)
Query Neighborhood Hits	270	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

LCE5A_HUMAN
θ value	θ > 10 (rank : 548)	NC score	0.054995 (rank : 680)
Query Neighborhood Hits	270	Target Neighborhood Hits	43	Shared Neighborhood Hits	9
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

LORI_MOUSE
θ value	θ > 10 (rank : 549)	NC score	0.095745 (rank : 462)
Query Neighborhood Hits	270	Target Neighborhood Hits	47	Shared Neighborhood Hits	16
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

LPHN1_HUMAN
θ value	θ > 10 (rank : 550)	NC score	0.052373 (rank : 710)
Query Neighborhood Hits	270	Target Neighborhood Hits	155	Shared Neighborhood Hits	13
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

LPHN2_HUMAN
θ value	θ > 10 (rank : 551)	NC score	0.052966 (rank : 704)
Query Neighborhood Hits	270	Target Neighborhood Hits	136	Shared Neighborhood Hits	13
SwissProt Accessions	O95490, O94882, Q5VX76, Q9UKY5, Q9UKY6	Gene names	LPHN2, KIAA0786, LEC1, LPHH1
Domain Architecture
Description	Latrophilin-2 precursor (Calcium-independent alpha-latrotoxin receptor 2) (Latrophilin homolog 1) (Lectomedin-1).

LPHN3_HUMAN
θ value	θ > 10 (rank : 552)	NC score	0.052099 (rank : 714)
Query Neighborhood Hits	270	Target Neighborhood Hits	139	Shared Neighborhood Hits	14
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

LRP10_HUMAN
θ value	θ > 10 (rank : 553)	NC score	0.106049 (rank : 441)
Query Neighborhood Hits	270	Target Neighborhood Hits	197	Shared Neighborhood Hits	56
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP10_MOUSE
θ value	θ > 10 (rank : 554)	NC score	0.108954 (rank : 436)
Query Neighborhood Hits	270	Target Neighborhood Hits	169	Shared Neighborhood Hits	57
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP12_HUMAN
θ value	θ > 10 (rank : 555)	NC score	0.144235 (rank : 381)
Query Neighborhood Hits	270	Target Neighborhood Hits	205	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
θ value	θ > 10 (rank : 556)	NC score	0.144958 (rank : 380)
Query Neighborhood Hits	270	Target Neighborhood Hits	180	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP3_HUMAN
θ value	θ > 10 (rank : 557)	NC score	0.162781 (rank : 367)
Query Neighborhood Hits	270	Target Neighborhood Hits	280	Shared Neighborhood Hits	94
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

LYAM1_HUMAN
θ value	θ > 10 (rank : 558)	NC score	0.221228 (rank : 300)
Query Neighborhood Hits	270	Target Neighborhood Hits	315	Shared Neighborhood Hits	144
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM1_MOUSE
θ value	θ > 10 (rank : 559)	NC score	0.225845 (rank : 297)
Query Neighborhood Hits	270	Target Neighborhood Hits	332	Shared Neighborhood Hits	149
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM2_HUMAN
θ value	θ > 10 (rank : 560)	NC score	0.294978 (rank : 235)
Query Neighborhood Hits	270	Target Neighborhood Hits	394	Shared Neighborhood Hits	181
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM2_MOUSE
θ value	θ > 10 (rank : 561)	NC score	0.290378 (rank : 244)
Query Neighborhood Hits	270	Target Neighborhood Hits	420	Shared Neighborhood Hits	193
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM3_HUMAN
θ value	θ > 10 (rank : 562)	NC score	0.281136 (rank : 262)
Query Neighborhood Hits	270	Target Neighborhood Hits	378	Shared Neighborhood Hits	188
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LYAM3_MOUSE
θ value	θ > 10 (rank : 563)	NC score	0.325758 (rank : 197)
Query Neighborhood Hits	270	Target Neighborhood Hits	390	Shared Neighborhood Hits	193
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MCPT1_HUMAN
θ value	θ > 10 (rank : 564)	NC score	0.052369 (rank : 711)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	28
SwissProt Accessions	P23946, Q16018	Gene names	CMA1, CYH, CYM
Domain Architecture
Description	Chymase precursor (EC 3.4.21.39) (Mast cell protease I).

MCPT1_MOUSE
θ value	θ > 10 (rank : 565)	NC score	0.053279 (rank : 699)
Query Neighborhood Hits	270	Target Neighborhood Hits	177	Shared Neighborhood Hits	28
SwissProt Accessions	P11034	Gene names	Mcpt1
Domain Architecture
Description	Mast cell protease 1 precursor (EC 3.4.21.-) (MMCP-1).

MCPT2_MOUSE
θ value	θ > 10 (rank : 566)	NC score	0.051258 (rank : 723)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	P15119	Gene names	Mcpt2
Domain Architecture
Description	Mast cell protease 2 precursor (EC 3.4.21.-) (MMCP-2).

MCPT4_MOUSE
θ value	θ > 10 (rank : 567)	NC score	0.050652 (rank : 727)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	P21812, Q9EPQ9, Q9EQT2	Gene names	Mcpt4
Domain Architecture
Description	Mast cell protease 4 precursor (EC 3.4.21.-) (MMCP-4) (Serosal mast cell protease) (MSMCP) (Myonase).

MCPT6_MOUSE
θ value	θ > 10 (rank : 568)	NC score	0.062004 (rank : 616)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	P21845, Q61962	Gene names	Mcpt6
Domain Architecture
Description	Mast cell protease 6 precursor (EC 3.4.21.59) (MMCP-6) (Tryptase).

MCPT8_MOUSE
θ value	θ > 10 (rank : 569)	NC score	0.051275 (rank : 722)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	P43430, Q9R1F1	Gene names	Mcpt8
Domain Architecture
Description	Mast cell protease 8 precursor (EC 3.4.21.-) (MMCP-8).

MCPT9_MOUSE
θ value	θ > 10 (rank : 570)	NC score	0.050455 (rank : 729)
Query Neighborhood Hits	270	Target Neighborhood Hits	174	Shared Neighborhood Hits	28
SwissProt Accessions	O35164	Gene names	Mcpt9
Domain Architecture
Description	Mast cell protease 9 precursor (EC 3.4.21.-) (MMCP-9).

MCSP_MOUSE
θ value	θ > 10 (rank : 571)	NC score	0.095295 (rank : 463)
Query Neighborhood Hits	270	Target Neighborhood Hits	108	Shared Neighborhood Hits	30
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MEGF9_HUMAN
θ value	θ > 10 (rank : 572)	NC score	0.371795 (rank : 163)
Query Neighborhood Hits	270	Target Neighborhood Hits	557	Shared Neighborhood Hits	173
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEGF9_MOUSE
θ value	θ > 10 (rank : 573)	NC score	0.340249 (rank : 185)
Query Neighborhood Hits	270	Target Neighborhood Hits	896	Shared Neighborhood Hits	164
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEP1A_HUMAN
θ value	θ > 10 (rank : 574)	NC score	0.196745 (rank : 329)
Query Neighborhood Hits	270	Target Neighborhood Hits	162	Shared Neighborhood Hits	116
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

MEP1A_MOUSE
θ value	θ > 10 (rank : 575)	NC score	0.203760 (rank : 321)
Query Neighborhood Hits	270	Target Neighborhood Hits	166	Shared Neighborhood Hits	116
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

MEP1B_HUMAN
θ value	θ > 10 (rank : 576)	NC score	0.087852 (rank : 494)
Query Neighborhood Hits	270	Target Neighborhood Hits	98	Shared Neighborhood Hits	51
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

MEP1B_MOUSE
θ value	θ > 10 (rank : 577)	NC score	0.130361 (rank : 405)
Query Neighborhood Hits	270	Target Neighborhood Hits	127	Shared Neighborhood Hits	76
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

MFGM_MOUSE
θ value	θ > 10 (rank : 578)	NC score	0.376731 (rank : 160)
Query Neighborhood Hits	270	Target Neighborhood Hits	233	Shared Neighborhood Hits	154
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

MFRP_HUMAN
θ value	θ > 10 (rank : 579)	NC score	0.106582 (rank : 440)
Query Neighborhood Hits	270	Target Neighborhood Hits	165	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_MOUSE
θ value	θ > 10 (rank : 580)	NC score	0.099248 (rank : 455)
Query Neighborhood Hits	270	Target Neighborhood Hits	166	Shared Neighborhood Hits	42
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MKS3_HUMAN
θ value	θ > 10 (rank : 581)	NC score	0.088872 (rank : 489)
Query Neighborhood Hits	270	Target Neighborhood Hits	79	Shared Neighborhood Hits	40
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

MKS3_MOUSE
θ value	θ > 10 (rank : 582)	NC score	0.078167 (rank : 534)
Query Neighborhood Hits	270	Target Neighborhood Hits	89	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

MMRN1_HUMAN
θ value	θ > 10 (rank : 583)	NC score	0.202105 (rank : 326)
Query Neighborhood Hits	270	Target Neighborhood Hits	636	Shared Neighborhood Hits	125
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

MT1A_HUMAN
θ value	θ > 10 (rank : 584)	NC score	0.060352 (rank : 638)
Query Neighborhood Hits	270	Target Neighborhood Hits	74	Shared Neighborhood Hits	25
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

MT1B_HUMAN
θ value	θ > 10 (rank : 585)	NC score	0.056266 (rank : 670)
Query Neighborhood Hits	270	Target Neighborhood Hits	87	Shared Neighborhood Hits	34
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

MT3_HUMAN
θ value	θ > 10 (rank : 586)	NC score	0.135202 (rank : 396)
Query Neighborhood Hits	270	Target Neighborhood Hits	82	Shared Neighborhood Hits	34
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

MT3_MOUSE
θ value	θ > 10 (rank : 587)	NC score	0.134960 (rank : 397)
Query Neighborhood Hits	270	Target Neighborhood Hits	68	Shared Neighborhood Hits	26
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

MUC13_HUMAN
θ value	θ > 10 (rank : 588)	NC score	0.138741 (rank : 388)
Query Neighborhood Hits	270	Target Neighborhood Hits	164	Shared Neighborhood Hits	80
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

MUC13_MOUSE
θ value	θ > 10 (rank : 589)	NC score	0.236071 (rank : 289)
Query Neighborhood Hits	270	Target Neighborhood Hits	447	Shared Neighborhood Hits	130
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

MUC2_HUMAN
θ value	θ > 10 (rank : 590)	NC score	0.110630 (rank : 434)
Query Neighborhood Hits	270	Target Neighborhood Hits	906	Shared Neighborhood Hits	111
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MUC5B_HUMAN
θ value	θ > 10 (rank : 591)	NC score	0.187184 (rank : 338)
Query Neighborhood Hits	270	Target Neighborhood Hits	1020	Shared Neighborhood Hits	158
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NAGPA_MOUSE
θ value	θ > 10 (rank : 592)	NC score	0.380851 (rank : 159)
Query Neighborhood Hits	270	Target Neighborhood Hits	308	Shared Neighborhood Hits	162
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NET1_HUMAN
θ value	θ > 10 (rank : 593)	NC score	0.131198 (rank : 404)
Query Neighborhood Hits	270	Target Neighborhood Hits	149	Shared Neighborhood Hits	78
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

NET1_MOUSE
θ value	θ > 10 (rank : 594)	NC score	0.124953 (rank : 414)
Query Neighborhood Hits	270	Target Neighborhood Hits	151	Shared Neighborhood Hits	78
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

NET2_HUMAN
θ value	θ > 10 (rank : 595)	NC score	0.167401 (rank : 361)
Query Neighborhood Hits	270	Target Neighborhood Hits	194	Shared Neighborhood Hits	105
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

NET2_MOUSE
θ value	θ > 10 (rank : 596)	NC score	0.166592 (rank : 362)
Query Neighborhood Hits	270	Target Neighborhood Hits	193	Shared Neighborhood Hits	105
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

NET4_HUMAN
θ value	θ > 10 (rank : 597)	NC score	0.163879 (rank : 366)
Query Neighborhood Hits	270	Target Neighborhood Hits	191	Shared Neighborhood Hits	104
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

NET4_MOUSE
θ value	θ > 10 (rank : 598)	NC score	0.158986 (rank : 372)
Query Neighborhood Hits	270	Target Neighborhood Hits	180	Shared Neighborhood Hits	105
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

NETO1_HUMAN
θ value	θ > 10 (rank : 599)	NC score	0.097050 (rank : 459)
Query Neighborhood Hits	270	Target Neighborhood Hits	110	Shared Neighborhood Hits	41
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
θ value	θ > 10 (rank : 600)	NC score	0.096917 (rank : 460)
Query Neighborhood Hits	270	Target Neighborhood Hits	109	Shared Neighborhood Hits	41
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO2_HUMAN
θ value	θ > 10 (rank : 601)	NC score	0.093541 (rank : 469)
Query Neighborhood Hits	270	Target Neighborhood Hits	109	Shared Neighborhood Hits	38
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
θ value	θ > 10 (rank : 602)	NC score	0.093910 (rank : 468)
Query Neighborhood Hits	270	Target Neighborhood Hits	113	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETR_HUMAN
θ value	θ > 10 (rank : 603)	NC score	0.061500 (rank : 621)
Query Neighborhood Hits	270	Target Neighborhood Hits	218	Shared Neighborhood Hits	28
SwissProt Accessions	P56730, Q9UP16	Gene names	PRSS12
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Leydin).

NETR_MOUSE
θ value	θ > 10 (rank : 604)	NC score	0.060848 (rank : 626)
Query Neighborhood Hits	270	Target Neighborhood Hits	216	Shared Neighborhood Hits	29
SwissProt Accessions	O08762	Gene names	Prss12, Bssp3
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Brain-specific serine protease 3) (BSSP-3).

NEU1_MOUSE
θ value	θ > 10 (rank : 605)	NC score	0.058100 (rank : 659)
Query Neighborhood Hits	270	Target Neighborhood Hits	64	Shared Neighborhood Hits	31
SwissProt Accessions	P35454	Gene names	Oxt
Domain Architecture
Description	Oxytocin-neurophysin 1 precursor (OT-NPI) [Contains: Oxytocin (Ocytocin); Neurophysin 1].

NFX1_HUMAN
θ value	θ > 10 (rank : 606)	NC score	0.200138 (rank : 328)
Query Neighborhood Hits	270	Target Neighborhood Hits	405	Shared Neighborhood Hits	93
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

NRG1_HUMAN
θ value	θ > 10 (rank : 607)	NC score	0.155710 (rank : 375)
Query Neighborhood Hits	270	Target Neighborhood Hits	285	Shared Neighborhood Hits	76
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

NRG2_HUMAN
θ value	θ > 10 (rank : 608)	NC score	0.137067 (rank : 394)
Query Neighborhood Hits	270	Target Neighborhood Hits	419	Shared Neighborhood Hits	86
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

NRG2_MOUSE
θ value	θ > 10 (rank : 609)	NC score	0.174186 (rank : 353)
Query Neighborhood Hits	270	Target Neighborhood Hits	392	Shared Neighborhood Hits	97
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

NRG3_HUMAN
θ value	θ > 10 (rank : 610)	NC score	0.057454 (rank : 663)
Query Neighborhood Hits	270	Target Neighborhood Hits	119	Shared Neighborhood Hits	46
SwissProt Accessions	P56975	Gene names	NRG3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

NRG3_MOUSE
θ value	θ > 10 (rank : 611)	NC score	0.059451 (rank : 648)
Query Neighborhood Hits	270	Target Neighborhood Hits	132	Shared Neighborhood Hits	49
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

NRG4_HUMAN
θ value	θ > 10 (rank : 612)	NC score	0.176463 (rank : 350)
Query Neighborhood Hits	270	Target Neighborhood Hits	85	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRG4_MOUSE
θ value	θ > 10 (rank : 613)	NC score	0.161928 (rank : 368)
Query Neighborhood Hits	270	Target Neighborhood Hits	79	Shared Neighborhood Hits	51
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRP1_HUMAN
θ value	θ > 10 (rank : 614)	NC score	0.085167 (rank : 506)
Query Neighborhood Hits	270	Target Neighborhood Hits	119	Shared Neighborhood Hits	26
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

NRP1_MOUSE
θ value	θ > 10 (rank : 615)	NC score	0.086164 (rank : 501)
Query Neighborhood Hits	270	Target Neighborhood Hits	120	Shared Neighborhood Hits	25
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NRP2_HUMAN
θ value	θ > 10 (rank : 616)	NC score	0.091385 (rank : 478)
Query Neighborhood Hits	270	Target Neighborhood Hits	120	Shared Neighborhood Hits	29
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_MOUSE
θ value	θ > 10 (rank : 617)	NC score	0.090573 (rank : 483)
Query Neighborhood Hits	270	Target Neighborhood Hits	113	Shared Neighborhood Hits	28
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRPN_HUMAN
θ value	θ > 10 (rank : 618)	NC score	0.060976 (rank : 624)
Query Neighborhood Hits	270	Target Neighborhood Hits	182	Shared Neighborhood Hits	30
SwissProt Accessions	O60259, Q9HCB3, Q9UIL9, Q9UQ47	Gene names	KLK8, NRPN, PRSS19, TADG14
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8) (Ovasin) (Serine protease TADG-14) (Tumor-associated differentially expressed gene 14 protein).

NRPN_MOUSE
θ value	θ > 10 (rank : 619)	NC score	0.059872 (rank : 644)
Query Neighborhood Hits	270	Target Neighborhood Hits	186	Shared Neighborhood Hits	30
SwissProt Accessions	Q61955	Gene names	Klk8, Nrpn, Prss19
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8).

NRX1A_HUMAN
θ value	θ > 10 (rank : 620)	NC score	0.203519 (rank : 324)
Query Neighborhood Hits	270	Target Neighborhood Hits	170	Shared Neighborhood Hits	102
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
θ value	θ > 10 (rank : 621)	NC score	0.203630 (rank : 323)
Query Neighborhood Hits	270	Target Neighborhood Hits	164	Shared Neighborhood Hits	101
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NTNG1_HUMAN
θ value	θ > 10 (rank : 622)	NC score	0.289881 (rank : 245)
Query Neighborhood Hits	270	Target Neighborhood Hits	247	Shared Neighborhood Hits	152
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG1_MOUSE
θ value	θ > 10 (rank : 623)	NC score	0.292098 (rank : 238)
Query Neighborhood Hits	270	Target Neighborhood Hits	246	Shared Neighborhood Hits	151
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

PAPPA_HUMAN
θ value	θ > 10 (rank : 624)	NC score	0.058999 (rank : 651)
Query Neighborhood Hits	270	Target Neighborhood Hits	161	Shared Neighborhood Hits	44
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PAPPA_MOUSE
θ value	θ > 10 (rank : 625)	NC score	0.065862 (rank : 585)
Query Neighborhood Hits	270	Target Neighborhood Hits	153	Shared Neighborhood Hits	47
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PCOC1_HUMAN
θ value	θ > 10 (rank : 626)	NC score	0.088900 (rank : 488)
Query Neighborhood Hits	270	Target Neighborhood Hits	146	Shared Neighborhood Hits	21
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC1_MOUSE
θ value	θ > 10 (rank : 627)	NC score	0.091535 (rank : 476)
Query Neighborhood Hits	270	Target Neighborhood Hits	100	Shared Neighborhood Hits	23
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC2_HUMAN
θ value	θ > 10 (rank : 628)	NC score	0.090599 (rank : 482)
Query Neighborhood Hits	270	Target Neighborhood Hits	73	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC2_MOUSE
θ value	θ > 10 (rank : 629)	NC score	0.088631 (rank : 491)
Query Neighborhood Hits	270	Target Neighborhood Hits	73	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCSK5_HUMAN
θ value	θ > 10 (rank : 630)	NC score	0.151108 (rank : 376)
Query Neighborhood Hits	270	Target Neighborhood Hits	291	Shared Neighborhood Hits	116
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

PCSK5_MOUSE
θ value	θ > 10 (rank : 631)	NC score	0.304980 (rank : 225)
Query Neighborhood Hits	270	Target Neighborhood Hits	613	Shared Neighborhood Hits	186
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

PCSK6_HUMAN
θ value	θ > 10 (rank : 632)	NC score	0.116542 (rank : 428)
Query Neighborhood Hits	270	Target Neighborhood Hits	298	Shared Neighborhood Hits	92
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

PDGFD_HUMAN
θ value	θ > 10 (rank : 633)	NC score	0.080705 (rank : 526)
Query Neighborhood Hits	270	Target Neighborhood Hits	74	Shared Neighborhood Hits	21
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

PDGFD_MOUSE
θ value	θ > 10 (rank : 634)	NC score	0.083533 (rank : 512)
Query Neighborhood Hits	270	Target Neighborhood Hits	72	Shared Neighborhood Hits	21
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

PGCA_MOUSE
θ value	θ > 10 (rank : 635)	NC score	0.071671 (rank : 556)
Query Neighborhood Hits	270	Target Neighborhood Hits	643	Shared Neighborhood Hits	23
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

PGH2_HUMAN
θ value	θ > 10 (rank : 636)	NC score	0.166019 (rank : 363)
Query Neighborhood Hits	270	Target Neighborhood Hits	103	Shared Neighborhood Hits	75
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

PGH2_MOUSE
θ value	θ > 10 (rank : 637)	NC score	0.173347 (rank : 355)
Query Neighborhood Hits	270	Target Neighborhood Hits	113	Shared Neighborhood Hits	83
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

PHXR5_MOUSE
θ value	θ > 10 (rank : 638)	NC score	0.250446 (rank : 278)
Query Neighborhood Hits	270	Target Neighborhood Hits	102	Shared Neighborhood Hits	76
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

PLMN_HUMAN
θ value	θ > 10 (rank : 639)	NC score	0.063488 (rank : 607)
Query Neighborhood Hits	270	Target Neighborhood Hits	204	Shared Neighborhood Hits	29
SwissProt Accessions	P00747, Q15146, Q6PA00	Gene names	PLG
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

PLMN_MOUSE
θ value	θ > 10 (rank : 640)	NC score	0.065187 (rank : 593)
Query Neighborhood Hits	270	Target Neighborhood Hits	208	Shared Neighborhood Hits	33
SwissProt Accessions	P20918, Q8CIS2, Q91WJ5	Gene names	Plg
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

POLS2_HUMAN
θ value	θ > 10 (rank : 641)	NC score	0.060672 (rank : 629)
Query Neighborhood Hits	270	Target Neighborhood Hits	192	Shared Neighborhood Hits	30
SwissProt Accessions	Q5K4E3, Q8NBY4	Gene names	PRSS36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

POLS2_MOUSE
θ value	θ > 10 (rank : 642)	NC score	0.060762 (rank : 627)
Query Neighborhood Hits	270	Target Neighborhood Hits	188	Shared Neighborhood Hits	28
SwissProt Accessions	Q5K2P8	Gene names	Prss36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

PRS27_HUMAN
θ value	θ > 10 (rank : 643)	NC score	0.065266 (rank : 591)
Query Neighborhood Hits	270	Target Neighborhood Hits	177	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BQR3	Gene names	PRSS27, MPN
Domain Architecture
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin) (Channel-activating protease 2) (CAPH2).

PRS27_MOUSE
θ value	θ > 10 (rank : 644)	NC score	0.064472 (rank : 599)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BJR6	Gene names	Prss27, Mpn
Domain Architecture	No domain graphic available
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin).

PRSS8_HUMAN
θ value	θ > 10 (rank : 645)	NC score	0.066859 (rank : 579)
Query Neighborhood Hits	270	Target Neighborhood Hits	177	Shared Neighborhood Hits	29
SwissProt Accessions	Q16651, Q9UCA3	Gene names	PRSS8
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) [Contains: Prostasin light chain; Prostasin heavy chain].

PRSS8_MOUSE
θ value	θ > 10 (rank : 646)	NC score	0.066881 (rank : 578)
Query Neighborhood Hits	270	Target Neighborhood Hits	177	Shared Neighborhood Hits	29
SwissProt Accessions	Q9ESD1	Gene names	Prss8, Cap1
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) (Channel-activating protease 1) [Contains: Prostasin light chain; Prostasin heavy chain].

PRTN3_HUMAN
θ value	θ > 10 (rank : 647)	NC score	0.051708 (rank : 717)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	P24158, P15637, P18078, Q6LBM7, Q9UQD8	Gene names	PRTN3, MBN
Domain Architecture
Description	Myeloblastin precursor (EC 3.4.21.76) (Leukocyte proteinase 3) (PR-3) (PR3) (AGP7) (Wegener autoantigen) (P29) (C-ANCA antigen) (Neutrophil proteinase 4) (NP-4).

PRTN3_MOUSE
θ value	θ > 10 (rank : 648)	NC score	0.050704 (rank : 726)
Query Neighborhood Hits	270	Target Neighborhood Hits	177	Shared Neighborhood Hits	28
SwissProt Accessions	Q61096, O08809	Gene names	Prtn3
Domain Architecture
Description	Myeloblastin precursor (EC 3.4.21.76) (Proteinase 3) (PR-3).

RECK_HUMAN
θ value	θ > 10 (rank : 649)	NC score	0.133017 (rank : 402)
Query Neighborhood Hits	270	Target Neighborhood Hits	189	Shared Neighborhood Hits	68
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

RECK_MOUSE
θ value	θ > 10 (rank : 650)	NC score	0.103586 (rank : 444)
Query Neighborhood Hits	270	Target Neighborhood Hits	158	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

RSPO3_HUMAN
θ value	θ > 10 (rank : 651)	NC score	0.075246 (rank : 544)
Query Neighborhood Hits	270	Target Neighborhood Hits	128	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

RSPO3_MOUSE
θ value	θ > 10 (rank : 652)	NC score	0.061403 (rank : 622)
Query Neighborhood Hits	270	Target Neighborhood Hits	120	Shared Neighborhood Hits	39
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

RSPO4_HUMAN
θ value	θ > 10 (rank : 653)	NC score	0.055411 (rank : 679)
Query Neighborhood Hits	270	Target Neighborhood Hits	110	Shared Neighborhood Hits	39
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

SEZ6L_HUMAN
θ value	θ > 10 (rank : 654)	NC score	0.077782 (rank : 535)
Query Neighborhood Hits	270	Target Neighborhood Hits	289	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

SHBG_HUMAN
θ value	θ > 10 (rank : 655)	NC score	0.093113 (rank : 472)
Query Neighborhood Hits	270	Target Neighborhood Hits	45	Shared Neighborhood Hits	19
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

SHBG_MOUSE
θ value	θ > 10 (rank : 656)	NC score	0.093537 (rank : 470)
Query Neighborhood Hits	270	Target Neighborhood Hits	50	Shared Neighborhood Hits	23
SwissProt Accessions	P97497	Gene names	Shbg
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP).

SMDF_HUMAN
θ value	θ > 10 (rank : 657)	NC score	0.168741 (rank : 359)
Query Neighborhood Hits	270	Target Neighborhood Hits	117	Shared Neighborhood Hits	65
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

SORL_HUMAN
θ value	θ > 10 (rank : 658)	NC score	0.291621 (rank : 239)
Query Neighborhood Hits	270	Target Neighborhood Hits	440	Shared Neighborhood Hits	147
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SORL_MOUSE
θ value	θ > 10 (rank : 659)	NC score	0.298708 (rank : 232)
Query Neighborhood Hits	270	Target Neighborhood Hits	439	Shared Neighborhood Hits	149
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

SPIT1_HUMAN
θ value	θ > 10 (rank : 660)	NC score	0.052387 (rank : 709)
Query Neighborhood Hits	270	Target Neighborhood Hits	100	Shared Neighborhood Hits	28
SwissProt Accessions	O43278, Q7Z7D2	Gene names	SPINT1, HAI1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

SPR2D_MOUSE
θ value	θ > 10 (rank : 661)	NC score	0.066639 (rank : 581)
Query Neighborhood Hits	270	Target Neighborhood Hits	61	Shared Neighborhood Hits	14
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

SPR2F_HUMAN
θ value	θ > 10 (rank : 662)	NC score	0.060391 (rank : 635)
Query Neighborhood Hits	270	Target Neighborhood Hits	33	Shared Neighborhood Hits	12
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

SPR2G_MOUSE
θ value	θ > 10 (rank : 663)	NC score	0.061729 (rank : 619)
Query Neighborhood Hits	270	Target Neighborhood Hits	53	Shared Neighborhood Hits	15
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

SPR2H_MOUSE
θ value	θ > 10 (rank : 664)	NC score	0.062203 (rank : 615)
Query Neighborhood Hits	270	Target Neighborhood Hits	82	Shared Neighborhood Hits	15
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

ST14_HUMAN
θ value	θ > 10 (rank : 665)	NC score	0.178820 (rank : 347)
Query Neighborhood Hits	270	Target Neighborhood Hits	409	Shared Neighborhood Hits	141
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

ST14_MOUSE
θ value	θ > 10 (rank : 666)	NC score	0.180310 (rank : 344)
Query Neighborhood Hits	270	Target Neighborhood Hits	419	Shared Neighborhood Hits	146
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

TECTA_HUMAN
θ value	θ > 10 (rank : 667)	NC score	0.150573 (rank : 377)
Query Neighborhood Hits	270	Target Neighborhood Hits	239	Shared Neighborhood Hits	129
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

TECTA_MOUSE
θ value	θ > 10 (rank : 668)	NC score	0.169032 (rank : 358)
Query Neighborhood Hits	270	Target Neighborhood Hits	244	Shared Neighborhood Hits	137
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TEFF2_HUMAN
θ value	θ > 10 (rank : 669)	NC score	0.216054 (rank : 306)
Query Neighborhood Hits	270	Target Neighborhood Hits	211	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
θ value	θ > 10 (rank : 670)	NC score	0.217810 (rank : 304)
Query Neighborhood Hits	270	Target Neighborhood Hits	214	Shared Neighborhood Hits	98
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TENA_HUMAN
θ value	θ > 10 (rank : 671)	NC score	0.444058 (rank : 143)
Query Neighborhood Hits	270	Target Neighborhood Hits	631	Shared Neighborhood Hits	206
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENN_HUMAN
θ value	θ > 10 (rank : 672)	NC score	0.221025 (rank : 301)
Query Neighborhood Hits	270	Target Neighborhood Hits	453	Shared Neighborhood Hits	160
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENN_MOUSE
θ value	θ > 10 (rank : 673)	NC score	0.235529 (rank : 290)
Query Neighborhood Hits	270	Target Neighborhood Hits	484	Shared Neighborhood Hits	163
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENR_HUMAN
θ value	θ > 10 (rank : 674)	NC score	0.282107 (rank : 260)
Query Neighborhood Hits	270	Target Neighborhood Hits	526	Shared Neighborhood Hits	174
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TENR_MOUSE
θ value	θ > 10 (rank : 675)	NC score	0.288287 (rank : 250)
Query Neighborhood Hits	270	Target Neighborhood Hits	531	Shared Neighborhood Hits	181
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

TEST_HUMAN
θ value	θ > 10 (rank : 676)	NC score	0.058727 (rank : 652)
Query Neighborhood Hits	270	Target Neighborhood Hits	172	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y6M0, Q9NS34, Q9P2V6	Gene names	PRSS21, ESP1, TEST1
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Eosinophil serine protease 1) (ESP- 1).

TEST_MOUSE
θ value	θ > 10 (rank : 677)	NC score	0.060608 (rank : 630)
Query Neighborhood Hits	270	Target Neighborhood Hits	174	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JHJ7, Q9DA14	Gene names	Prss21
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Tryptase 4).

TGFA_HUMAN
θ value	θ > 10 (rank : 678)	NC score	0.071310 (rank : 558)
Query Neighborhood Hits	270	Target Neighborhood Hits	61	Shared Neighborhood Hits	37
SwissProt Accessions	P01135, Q15577	Gene names	TGFA
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

TGFA_MOUSE
θ value	θ > 10 (rank : 679)	NC score	0.055676 (rank : 676)
Query Neighborhood Hits	270	Target Neighborhood Hits	62	Shared Neighborhood Hits	33
SwissProt Accessions	P48030	Gene names	Tgfa
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

THRB_HUMAN
θ value	θ > 10 (rank : 680)	NC score	0.093050 (rank : 473)
Query Neighborhood Hits	270	Target Neighborhood Hits	196	Shared Neighborhood Hits	32
SwissProt Accessions	P00734	Gene names	F2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

THRB_MOUSE
θ value	θ > 10 (rank : 681)	NC score	0.091188 (rank : 479)
Query Neighborhood Hits	270	Target Neighborhood Hits	195	Shared Neighborhood Hits	32
SwissProt Accessions	P19221	Gene names	F2, Cf2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

TM11D_HUMAN
θ value	θ > 10 (rank : 682)	NC score	0.067561 (rank : 572)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	28
SwissProt Accessions	O60235	Gene names	TMPRSS11D, HAT
Domain Architecture
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

TM11D_MOUSE
θ value	θ > 10 (rank : 683)	NC score	0.067335 (rank : 575)
Query Neighborhood Hits	270	Target Neighborhood Hits	179	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VHK8, Q7TNX3, Q8VDV1	Gene names	Tmprss11d, Mat
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) (AT) (Adrenal secretory serine protease) (AsP) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

TM11E_HUMAN
θ value	θ > 10 (rank : 684)	NC score	0.067547 (rank : 573)
Query Neighborhood Hits	270	Target Neighborhood Hits	181	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UL52, Q6UW31	Gene names	TMPRSS11E, DESC1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

TM11E_MOUSE
θ value	θ > 10 (rank : 685)	NC score	0.065719 (rank : 588)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	27
SwissProt Accessions	Q5S248, Q8BM10	Gene names	Tmprss11e, Desc1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

TMG1_HUMAN
θ value	θ > 10 (rank : 686)	NC score	0.157741 (rank : 374)
Query Neighborhood Hits	270	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	O14668	Gene names	PRRG1, PRGP1, TMG1
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 1 precursor (Proline- rich Gla protein 1) (Proline-rich gamma-carboxyglutamic acid protein 1).

TMG2_HUMAN
θ value	θ > 10 (rank : 687)	NC score	0.121189 (rank : 421)
Query Neighborhood Hits	270	Target Neighborhood Hits	25	Shared Neighborhood Hits	14
SwissProt Accessions	O14669	Gene names	PRRG2, PRGP2, TMG2
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 2 precursor (Proline- rich Gla protein 2) (Proline-rich gamma-carboxyglutamic acid protein 2).

TMG2_MOUSE
θ value	θ > 10 (rank : 688)	NC score	0.121285 (rank : 419)
Query Neighborhood Hits	270	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R182, Q9EQI2	Gene names	Prrg2, N4wbp1
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 2 precursor (Proline- rich Gla protein 2) (Proline-rich gamma-carboxyglutamic acid protein 2) (NEDD4 WW domain-binding protein 1).

TMG3_HUMAN
θ value	θ > 10 (rank : 689)	NC score	0.143788 (rank : 382)
Query Neighborhood Hits	270	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BZD7, Q8N2N6	Gene names	PRRG3, TMG3
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 3 precursor (Proline- rich Gla protein 3) (Proline-rich gamma-carboxyglutamic acid protein 3).

TMG3_MOUSE
θ value	θ > 10 (rank : 690)	NC score	0.141517 (rank : 384)
Query Neighborhood Hits	270	Target Neighborhood Hits	30	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PAQ9	Gene names	Prrg3, Gm368, Tmg3
Domain Architecture	No domain graphic available
Description	Transmembrane gamma-carboxyglutamic acid protein 3 precursor (Proline- rich Gla protein 3) (Proline-rich gamma-carboxyglutamic acid protein 3).

TMG4_HUMAN
θ value	θ > 10 (rank : 691)	NC score	0.121716 (rank : 418)
Query Neighborhood Hits	270	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BZD6	Gene names	PRRG4, TMG4
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline- rich Gla protein 4) (Proline-rich gamma-carboxyglutamic acid protein 4).

TMG4_MOUSE
θ value	θ > 10 (rank : 692)	NC score	0.109758 (rank : 435)
Query Neighborhood Hits	270	Target Neighborhood Hits	24	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BGN6, Q8BM25	Gene names	Prrg4, Tmg4
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline- rich Gla protein 4) (Proline-rich gamma-carboxyglutamic acid protein 4).

TMPS2_HUMAN
θ value	θ > 10 (rank : 693)	NC score	0.071149 (rank : 559)
Query Neighborhood Hits	270	Target Neighborhood Hits	252	Shared Neighborhood Hits	48
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS2_MOUSE
θ value	θ > 10 (rank : 694)	NC score	0.074723 (rank : 547)
Query Neighborhood Hits	270	Target Neighborhood Hits	243	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JIQ8, Q9JKC4, Q9QY82	Gene names	Tmprss2
Domain Architecture
Description	Transmembrane protease, serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS3_HUMAN
θ value	θ > 10 (rank : 695)	NC score	0.070401 (rank : 562)
Query Neighborhood Hits	270	Target Neighborhood Hits	245	Shared Neighborhood Hits	47
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

TMPS3_MOUSE
θ value	θ > 10 (rank : 696)	NC score	0.072406 (rank : 553)
Query Neighborhood Hits	270	Target Neighborhood Hits	239	Shared Neighborhood Hits	51
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

TMPS4_HUMAN
θ value	θ > 10 (rank : 697)	NC score	0.069763 (rank : 564)
Query Neighborhood Hits	270	Target Neighborhood Hits	203	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NRS4, Q5XKQ6, Q6UX37, Q9NZA5	Gene names	TMPRSS4, TMPRSS3
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Membrane-type serine protease 2) (MT-SP2).

TMPS4_MOUSE
θ value	θ > 10 (rank : 698)	NC score	0.067616 (rank : 571)
Query Neighborhood Hits	270	Target Neighborhood Hits	210	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VCA5	Gene names	Tmprss4, Cap2
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (mCAP2).

TMPS5_HUMAN
θ value	θ > 10 (rank : 699)	NC score	0.059116 (rank : 650)
Query Neighborhood Hits	270	Target Neighborhood Hits	181	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H3S3	Gene names	TMPRSS5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

TMPS5_MOUSE
θ value	θ > 10 (rank : 700)	NC score	0.060131 (rank : 639)
Query Neighborhood Hits	270	Target Neighborhood Hits	185	Shared Neighborhood Hits	29
SwissProt Accessions	Q9ER04, Q9ER02, Q9ER03	Gene names	Tmprss5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

TMPS6_HUMAN
θ value	θ > 10 (rank : 701)	NC score	0.138046 (rank : 391)
Query Neighborhood Hits	270	Target Neighborhood Hits	338	Shared Neighborhood Hits	112
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS6_MOUSE
θ value	θ > 10 (rank : 702)	NC score	0.135646 (rank : 395)
Query Neighborhood Hits	270	Target Neighborhood Hits	341	Shared Neighborhood Hits	115
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS7_HUMAN
θ value	θ > 10 (rank : 703)	NC score	0.102583 (rank : 448)
Query Neighborhood Hits	270	Target Neighborhood Hits	275	Shared Neighborhood Hits	71
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS7_MOUSE
θ value	θ > 10 (rank : 704)	NC score	0.101043 (rank : 451)
Query Neighborhood Hits	270	Target Neighborhood Hits	275	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS9_HUMAN
θ value	θ > 10 (rank : 705)	NC score	0.077015 (rank : 538)
Query Neighborhood Hits	270	Target Neighborhood Hits	276	Shared Neighborhood Hits	51
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

TMPS9_MOUSE
θ value	θ > 10 (rank : 706)	NC score	0.076617 (rank : 540)
Query Neighborhood Hits	270	Target Neighborhood Hits	296	Shared Neighborhood Hits	48
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

TMPSD_HUMAN
θ value	θ > 10 (rank : 707)	NC score	0.064289 (rank : 603)
Query Neighborhood Hits	270	Target Neighborhood Hits	333	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TMPSD_MOUSE
θ value	θ > 10 (rank : 708)	NC score	0.064433 (rank : 600)
Query Neighborhood Hits	270	Target Neighborhood Hits	334	Shared Neighborhood Hits	33
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TMSP8_MOUSE
θ value	θ > 10 (rank : 709)	NC score	0.069248 (rank : 565)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QYZ9, Q91XC4	Gene names	Tmprss8, Disp
Domain Architecture
Description	Transmembrane serine protease 8 precursor (EC 3.4.21.-) (Distal intestinal serine protease).

TNR11_HUMAN
θ value	θ > 10 (rank : 710)	NC score	0.059993 (rank : 641)
Query Neighborhood Hits	270	Target Neighborhood Hits	135	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR16_HUMAN
θ value	θ > 10 (rank : 711)	NC score	0.078897 (rank : 531)
Query Neighborhood Hits	270	Target Neighborhood Hits	183	Shared Neighborhood Hits	55
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR16_MOUSE
θ value	θ > 10 (rank : 712)	NC score	0.076681 (rank : 539)
Query Neighborhood Hits	270	Target Neighborhood Hits	178	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR25_HUMAN
θ value	θ > 10 (rank : 713)	NC score	0.098446 (rank : 456)
Query Neighborhood Hits	270	Target Neighborhood Hits	172	Shared Neighborhood Hits	50
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TNR7_HUMAN
θ value	θ > 10 (rank : 714)	NC score	0.053137 (rank : 703)
Query Neighborhood Hits	270	Target Neighborhood Hits	120	Shared Neighborhood Hits	40
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TNR8_MOUSE
θ value	θ > 10 (rank : 715)	NC score	0.056353 (rank : 669)
Query Neighborhood Hits	270	Target Neighborhood Hits	208	Shared Neighborhood Hits	41
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TNR9_HUMAN
θ value	θ > 10 (rank : 716)	NC score	0.073318 (rank : 550)
Query Neighborhood Hits	270	Target Neighborhood Hits	166	Shared Neighborhood Hits	46
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TRY1_HUMAN
θ value	θ > 10 (rank : 717)	NC score	0.061865 (rank : 618)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	28
SwissProt Accessions	P07477, Q92955, Q9HAN4, Q9HAN5, Q9HAN6, Q9HAN7	Gene names	PRSS1, TRP1, TRY1, TRYP1
Domain Architecture
Description	Trypsin-1 precursor (EC 3.4.21.4) (Trypsin I) (Cationic trypsinogen).

TRY2_HUMAN
θ value	θ > 10 (rank : 718)	NC score	0.063449 (rank : 608)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	27
SwissProt Accessions	P07478	Gene names	PRSS2, TRY2, TRYP2
Domain Architecture
Description	Trypsin-2 precursor (EC 3.4.21.4) (Trypsin II) (Anionic trypsinogen).

TRY2_MOUSE
θ value	θ > 10 (rank : 719)	NC score	0.062304 (rank : 613)
Query Neighborhood Hits	270	Target Neighborhood Hits	174	Shared Neighborhood Hits	28
SwissProt Accessions	P07146	Gene names	Prss2, Try2
Domain Architecture
Description	Anionic trypsin-2 precursor (EC 3.4.21.4) (Anionic trypsin II) (Pretrypsinogen II).

TRY3_HUMAN
θ value	θ > 10 (rank : 720)	NC score	0.064296 (rank : 602)
Query Neighborhood Hits	270	Target Neighborhood Hits	178	Shared Neighborhood Hits	29
SwissProt Accessions	P35030, P15951, Q15665, Q9UQV3	Gene names	PRSS3, PRSS4, TRY3, TRY4
Domain Architecture
Description	Trypsin-3 precursor (EC 3.4.21.4) (Trypsin III) (Brain trypsinogen) (Mesotrypsinogen) (Trypsin IV).

TRYA1_HUMAN
θ value	θ > 10 (rank : 721)	NC score	0.059456 (rank : 647)
Query Neighborhood Hits	270	Target Neighborhood Hits	177	Shared Neighborhood Hits	28
SwissProt Accessions	P15157, Q9H2Y5, Q9UQI1	Gene names	TPSAB1, TPS1
Domain Architecture
Description	Tryptase alpha-1 precursor (EC 3.4.21.59) (Tryptase-1).

TRYB1_HUMAN
θ value	θ > 10 (rank : 722)	NC score	0.060364 (rank : 636)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	Q15661, Q15663, Q9H2Y4	Gene names	TPSAB1, TPSB1
Domain Architecture
Description	Tryptase beta-1 precursor (EC 3.4.21.59) (Tryptase-1) (Tryptase I).

TRYB1_MOUSE
θ value	θ > 10 (rank : 723)	NC score	0.059460 (rank : 646)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	Q02844	Gene names	Tpsab1, Mcpt7
Domain Architecture
Description	Tryptase precursor (EC 3.4.21.59) (Mast cell protease 7) (MMCP-7) (Tryptase alpha/beta-1).

TRYB2_HUMAN
θ value	θ > 10 (rank : 724)	NC score	0.060364 (rank : 637)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	P20231, O95827, Q15664, Q9UQI6, Q9UQI7	Gene names	TPSB2, TPS2
Domain Architecture
Description	Tryptase beta-2 precursor (EC 3.4.21.59) (Tryptase-2) (Tryptase II).

TRYD_HUMAN
θ value	θ > 10 (rank : 725)	NC score	0.055610 (rank : 677)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BZJ3, O95824, Q8TDI6, Q96L36, Q96RZ5, Q9H2Y6, Q9UQI8	Gene names	TPSD1
Domain Architecture
Description	Tryptase delta precursor (EC 3.4.21.59) (Delta tryptase) (Mast cell mMCP-7-like) (Tryptase-3) (HmMCP-3-like tryptase III).

TRYG1_HUMAN
θ value	θ > 10 (rank : 726)	NC score	0.065309 (rank : 590)
Query Neighborhood Hits	270	Target Neighborhood Hits	179	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NRR2, Q96RZ8, Q9C015, Q9NRQ8, Q9UBB2	Gene names	TPSG1, TMT
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

TRYG1_MOUSE
θ value	θ > 10 (rank : 727)	NC score	0.063791 (rank : 605)
Query Neighborhood Hits	270	Target Neighborhood Hits	181	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QUL7	Gene names	Tpsg1, Tmt
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

TSG6_HUMAN
θ value	θ > 10 (rank : 728)	NC score	0.118765 (rank : 423)
Query Neighborhood Hits	270	Target Neighborhood Hits	91	Shared Neighborhood Hits	34
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
θ value	θ > 10 (rank : 729)	NC score	0.117841 (rank : 424)
Query Neighborhood Hits	270	Target Neighborhood Hits	91	Shared Neighborhood Hits	33
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

TSP1_HUMAN
θ value	θ > 10 (rank : 730)	NC score	0.347150 (rank : 178)
Query Neighborhood Hits	270	Target Neighborhood Hits	389	Shared Neighborhood Hits	162
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_MOUSE
θ value	θ > 10 (rank : 731)	NC score	0.348631 (rank : 176)
Query Neighborhood Hits	270	Target Neighborhood Hits	396	Shared Neighborhood Hits	168
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP2_HUMAN
θ value	θ > 10 (rank : 732)	NC score	0.319381 (rank : 207)
Query Neighborhood Hits	270	Target Neighborhood Hits	359	Shared Neighborhood Hits	156
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP2_MOUSE
θ value	θ > 10 (rank : 733)	NC score	0.306899 (rank : 223)
Query Neighborhood Hits	270	Target Neighborhood Hits	352	Shared Neighborhood Hits	156
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP50_HUMAN
θ value	θ > 10 (rank : 734)	NC score	0.060708 (rank : 628)
Query Neighborhood Hits	270	Target Neighborhood Hits	178	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UI38	Gene names	TSP50
Domain Architecture
Description	Testis-specific protease-like protein 50 precursor.

USH2A_HUMAN
θ value	θ > 10 (rank : 735)	NC score	0.249373 (rank : 280)
Query Neighborhood Hits	270	Target Neighborhood Hits	600	Shared Neighborhood Hits	150
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

USH2A_MOUSE
θ value	θ > 10 (rank : 736)	NC score	0.263745 (rank : 270)
Query Neighborhood Hits	270	Target Neighborhood Hits	626	Shared Neighborhood Hits	157
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

VASN_HUMAN
θ value	θ > 10 (rank : 737)	NC score	0.133887 (rank : 401)
Query Neighborhood Hits	270	Target Neighborhood Hits	449	Shared Neighborhood Hits	114
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

VASN_MOUSE
θ value	θ > 10 (rank : 738)	NC score	0.129516 (rank : 407)
Query Neighborhood Hits	270	Target Neighborhood Hits	426	Shared Neighborhood Hits	111
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

VEGFC_HUMAN
θ value	θ > 10 (rank : 739)	NC score	0.094027 (rank : 467)
Query Neighborhood Hits	270	Target Neighborhood Hits	128	Shared Neighborhood Hits	60
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

VEGFC_MOUSE
θ value	θ > 10 (rank : 740)	NC score	0.084278 (rank : 511)
Query Neighborhood Hits	270	Target Neighborhood Hits	119	Shared Neighborhood Hits	59
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

VWF_HUMAN
θ value	θ > 10 (rank : 741)	NC score	0.192971 (rank : 333)
Query Neighborhood Hits	270	Target Neighborhood Hits	396	Shared Neighborhood Hits	123
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

VWF_MOUSE
θ value	θ > 10 (rank : 742)	NC score	0.181066 (rank : 343)
Query Neighborhood Hits	270	Target Neighborhood Hits	381	Shared Neighborhood Hits	114
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

WFDC3_HUMAN
θ value	θ > 10 (rank : 743)	NC score	0.105497 (rank : 443)
Query Neighborhood Hits	270	Target Neighborhood Hits	138	Shared Neighborhood Hits	47
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

WISP2_HUMAN
θ value	θ > 10 (rank : 744)	NC score	0.051238 (rank : 724)
Query Neighborhood Hits	270	Target Neighborhood Hits	126	Shared Neighborhood Hits	25
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

XLKD1_MOUSE
θ value	θ > 10 (rank : 745)	NC score	0.050201 (rank : 733)
Query Neighborhood Hits	270	Target Neighborhood Hits	31	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BHC0, Q3TUC1, Q99NE4	Gene names	Xlkd1, Crsbp1
Domain Architecture	No domain graphic available
Description	Lymphatic vessel endothelial hyaluronic acid receptor 1 precursor (LYVE-1) (Cell surface retention sequence-binding protein 1) (CRSBP-1) (Extracellular link domain-containing protein 1).

ZAN_HUMAN
θ value	θ > 10 (rank : 746)	NC score	0.249422 (rank : 279)
Query Neighborhood Hits	270	Target Neighborhood Hits	679	Shared Neighborhood Hits	180
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ZAN_MOUSE
θ value	θ > 10 (rank : 747)	NC score	0.426501 (rank : 147)
Query Neighborhood Hits	270	Target Neighborhood Hits	808	Shared Neighborhood Hits	219
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

Hits sorted by NC score

EGFL8_HUMAN
NC score	0.999962 (rank : 1)	θ value	9.49765e-159 (rank : 1)
Query Neighborhood Hits	270	Target Neighborhood Hits	270	Shared Neighborhood Hits	270
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL8_MOUSE
NC score	0.985413 (rank : 2)	θ value	1.2462e-142 (rank : 2)
Query Neighborhood Hits	270	Target Neighborhood Hits	266	Shared Neighborhood Hits	240
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EGFL7_HUMAN
NC score	0.909491 (rank : 3)	θ value	2.05049e-36 (rank : 3)
Query Neighborhood Hits	270	Target Neighborhood Hits	325	Shared Neighborhood Hits	228
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL7_MOUSE
NC score	0.905990 (rank : 4)	θ value	6.59618e-35 (rank : 4)
Query Neighborhood Hits	270	Target Neighborhood Hits	287	Shared Neighborhood Hits	223
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

GAS6_HUMAN
NC score	0.763043 (rank : 5)	θ value	3.08544e-08 (rank : 28)
Query Neighborhood Hits	270	Target Neighborhood Hits	348	Shared Neighborhood Hits	227
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GAS6_MOUSE
NC score	0.761455 (rank : 6)	θ value	1.38499e-08 (rank : 26)
Query Neighborhood Hits	270	Target Neighborhood Hits	343	Shared Neighborhood Hits	230
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

C1QR1_MOUSE
NC score	0.761334 (rank : 7)	θ value	4.45536e-07 (rank : 44)
Query Neighborhood Hits	270	Target Neighborhood Hits	342	Shared Neighborhood Hits	217
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

C1QR1_HUMAN
NC score	0.758061 (rank : 8)	θ value	1.99992e-07 (rank : 42)
Query Neighborhood Hits	270	Target Neighborhood Hits	493	Shared Neighborhood Hits	227
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

PROS_HUMAN
NC score	0.754674 (rank : 9)	θ value	7.59969e-07 (rank : 47)
Query Neighborhood Hits	270	Target Neighborhood Hits	340	Shared Neighborhood Hits	226
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

FBLN5_HUMAN
NC score	0.751655 (rank : 10)	θ value	1.53129e-07 (rank : 40)
Query Neighborhood Hits	270	Target Neighborhood Hits	329	Shared Neighborhood Hits	211
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
NC score	0.751073 (rank : 11)	θ value	6.87365e-08 (rank : 36)
Query Neighborhood Hits	270	Target Neighborhood Hits	317	Shared Neighborhood Hits	209
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

PROS_MOUSE
NC score	0.750407 (rank : 12)	θ value	4.92598e-06 (rank : 59)
Query Neighborhood Hits	270	Target Neighborhood Hits	330	Shared Neighborhood Hits	223
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

CRUM2_HUMAN
NC score	0.748691 (rank : 13)	θ value	1.17247e-07 (rank : 38)
Query Neighborhood Hits	270	Target Neighborhood Hits	453	Shared Neighborhood Hits	243
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

FBN3_HUMAN
NC score	0.748281 (rank : 14)	θ value	2.52405e-10 (rank : 9)
Query Neighborhood Hits	270	Target Neighborhood Hits	543	Shared Neighborhood Hits	248
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FBLN1_HUMAN
NC score	0.747899 (rank : 15)	θ value	5.26297e-08 (rank : 33)
Query Neighborhood Hits	270	Target Neighborhood Hits	324	Shared Neighborhood Hits	209
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBN2_MOUSE
NC score	0.746715 (rank : 16)	θ value	7.84624e-12 (rank : 5)
Query Neighborhood Hits	270	Target Neighborhood Hits	549	Shared Neighborhood Hits	249
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_HUMAN
NC score	0.744034 (rank : 17)	θ value	1.74796e-11 (rank : 6)
Query Neighborhood Hits	270	Target Neighborhood Hits	560	Shared Neighborhood Hits	249
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBLN1_MOUSE
NC score	0.743403 (rank : 18)	θ value	8.97725e-08 (rank : 37)
Query Neighborhood Hits	270	Target Neighborhood Hits	329	Shared Neighborhood Hits	209
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN4_HUMAN
NC score	0.743177 (rank : 19)	θ value	6.43352e-06 (rank : 65)
Query Neighborhood Hits	270	Target Neighborhood Hits	278	Shared Neighborhood Hits	204
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN2_HUMAN
NC score	0.742857 (rank : 20)	θ value	2.21117e-06 (rank : 54)
Query Neighborhood Hits	270	Target Neighborhood Hits	392	Shared Neighborhood Hits	208
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

NELL2_MOUSE
NC score	0.742802 (rank : 21)	θ value	4.76016e-09 (rank : 20)
Query Neighborhood Hits	270	Target Neighborhood Hits	436	Shared Neighborhood Hits	240
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

JAG2_MOUSE
NC score	0.742597 (rank : 22)	θ value	9.59137e-10 (rank : 12)
Query Neighborhood Hits	270	Target Neighborhood Hits	504	Shared Neighborhood Hits	242
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

FBN1_HUMAN
NC score	0.742386 (rank : 23)	θ value	1.06045e-08 (rank : 25)
Query Neighborhood Hits	270	Target Neighborhood Hits	557	Shared Neighborhood Hits	250
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

JAG2_HUMAN
NC score	0.742334 (rank : 24)	θ value	2.13673e-09 (rank : 14)
Query Neighborhood Hits	270	Target Neighborhood Hits	491	Shared Neighborhood Hits	244
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

NELL2_HUMAN
NC score	0.742249 (rank : 25)	θ value	4.76016e-09 (rank : 19)
Query Neighborhood Hits	270	Target Neighborhood Hits	449	Shared Neighborhood Hits	239
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

FBN1_MOUSE
NC score	0.741690 (rank : 26)	θ value	3.08544e-08 (rank : 27)
Query Neighborhood Hits	270	Target Neighborhood Hits	563	Shared Neighborhood Hits	254
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

LTBP4_MOUSE
NC score	0.741079 (rank : 27)	θ value	1.87187e-05 (rank : 72)
Query Neighborhood Hits	270	Target Neighborhood Hits	607	Shared Neighborhood Hits	243
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

FBLN4_MOUSE
NC score	0.738716 (rank : 28)	θ value	6.43352e-06 (rank : 66)
Query Neighborhood Hits	270	Target Neighborhood Hits	270	Shared Neighborhood Hits	202
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

DLL1_MOUSE
NC score	0.738480 (rank : 29)	θ value	8.11959e-09 (rank : 23)
Query Neighborhood Hits	270	Target Neighborhood Hits	456	Shared Neighborhood Hits	243
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

CRUM1_MOUSE
NC score	0.737550 (rank : 30)	θ value	4.0297e-08 (rank : 29)
Query Neighborhood Hits	270	Target Neighborhood Hits	444	Shared Neighborhood Hits	240
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CRUM1_HUMAN
NC score	0.736655 (rank : 31)	θ value	6.21693e-09 (rank : 22)
Query Neighborhood Hits	270	Target Neighborhood Hits	457	Shared Neighborhood Hits	239
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

FBLN2_MOUSE
NC score	0.736601 (rank : 32)	θ value	1.69304e-06 (rank : 53)
Query Neighborhood Hits	270	Target Neighborhood Hits	505	Shared Neighborhood Hits	220
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

JAG1_HUMAN
NC score	0.736568 (rank : 33)	θ value	2.79066e-09 (rank : 15)
Query Neighborhood Hits	270	Target Neighborhood Hits	514	Shared Neighborhood Hits	244
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
NC score	0.735496 (rank : 34)	θ value	4.0297e-08 (rank : 31)
Query Neighborhood Hits	270	Target Neighborhood Hits	518	Shared Neighborhood Hits	243
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

DLL1_HUMAN
NC score	0.734832 (rank : 35)	θ value	1.53129e-07 (rank : 39)
Query Neighborhood Hits	270	Target Neighborhood Hits	455	Shared Neighborhood Hits	240
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

NELL1_HUMAN
NC score	0.734095 (rank : 36)	θ value	2.98157e-11 (rank : 7)
Query Neighborhood Hits	270	Target Neighborhood Hits	451	Shared Neighborhood Hits	232
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

EGFL9_MOUSE
NC score	0.733643 (rank : 37)	θ value	6.43352e-06 (rank : 64)
Query Neighborhood Hits	270	Target Neighborhood Hits	379	Shared Neighborhood Hits	226
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

LTBP3_MOUSE
NC score	0.733537 (rank : 38)	θ value	3.19293e-05 (rank : 78)
Query Neighborhood Hits	270	Target Neighborhood Hits	475	Shared Neighborhood Hits	242
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

FBLN3_HUMAN
NC score	0.732986 (rank : 39)	θ value	1.09739e-05 (rank : 69)
Query Neighborhood Hits	270	Target Neighborhood Hits	293	Shared Neighborhood Hits	205
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

DNER_MOUSE
NC score	0.732369 (rank : 40)	θ value	2.61198e-07 (rank : 43)
Query Neighborhood Hits	270	Target Neighborhood Hits	413	Shared Neighborhood Hits	226
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

LTBP3_HUMAN
NC score	0.730947 (rank : 41)	θ value	4.1701e-05 (rank : 81)
Query Neighborhood Hits	270	Target Neighborhood Hits	502	Shared Neighborhood Hits	240
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

FBLN3_MOUSE
NC score	0.730280 (rank : 42)	θ value	1.09739e-05 (rank : 70)
Query Neighborhood Hits	270	Target Neighborhood Hits	279	Shared Neighborhood Hits	200
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

LTB1L_MOUSE
NC score	0.729639 (rank : 43)	θ value	4.0297e-08 (rank : 32)
Query Neighborhood Hits	270	Target Neighborhood Hits	514	Shared Neighborhood Hits	249
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

DNER_HUMAN
NC score	0.729410 (rank : 44)	θ value	4.92598e-06 (rank : 57)
Query Neighborhood Hits	270	Target Neighborhood Hits	460	Shared Neighborhood Hits	228
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

EGFL9_HUMAN
NC score	0.729153 (rank : 45)	θ value	1.09739e-05 (rank : 68)
Query Neighborhood Hits	270	Target Neighborhood Hits	365	Shared Neighborhood Hits	225
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

DLK_MOUSE
NC score	0.726314 (rank : 46)	θ value	7.59969e-07 (rank : 46)
Query Neighborhood Hits	270	Target Neighborhood Hits	374	Shared Neighborhood Hits	222
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

LTB1L_HUMAN
NC score	0.725144 (rank : 47)	θ value	5.26297e-08 (rank : 34)
Query Neighborhood Hits	270	Target Neighborhood Hits	553	Shared Neighborhood Hits	245
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

DLL3_MOUSE
NC score	0.723453 (rank : 48)	θ value	1.09739e-05 (rank : 67)
Query Neighborhood Hits	270	Target Neighborhood Hits	399	Shared Neighborhood Hits	223
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

LTB1S_MOUSE
NC score	0.721995 (rank : 49)	θ value	0.000121331 (rank : 92)
Query Neighborhood Hits	270	Target Neighborhood Hits	479	Shared Neighborhood Hits	245
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

DLL4_HUMAN
NC score	0.719524 (rank : 50)	θ value	3.19293e-05 (rank : 76)
Query Neighborhood Hits	270	Target Neighborhood Hits	435	Shared Neighborhood Hits	227
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL4_MOUSE
NC score	0.719508 (rank : 51)	θ value	9.92553e-07 (rank : 48)
Query Neighborhood Hits	270	Target Neighborhood Hits	440	Shared Neighborhood Hits	226
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

LTBP2_MOUSE
NC score	0.719233 (rank : 52)	θ value	0.000121331 (rank : 93)
Query Neighborhood Hits	270	Target Neighborhood Hits	617	Shared Neighborhood Hits	243
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP2_HUMAN
NC score	0.718301 (rank : 53)	θ value	2.44474e-05 (rank : 73)
Query Neighborhood Hits	270	Target Neighborhood Hits	552	Shared Neighborhood Hits	246
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTB1S_HUMAN
NC score	0.718260 (rank : 54)	θ value	0.000158464 (rank : 94)
Query Neighborhood Hits	270	Target Neighborhood Hits	502	Shared Neighborhood Hits	244
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

DLK_HUMAN
NC score	0.717904 (rank : 55)	θ value	5.44631e-05 (rank : 85)
Query Neighborhood Hits	270	Target Neighborhood Hits	401	Shared Neighborhood Hits	223
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLL3_HUMAN
NC score	0.717749 (rank : 56)	θ value	1.43324e-05 (rank : 71)
Query Neighborhood Hits	270	Target Neighborhood Hits	419	Shared Neighborhood Hits	221
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

SCUB3_MOUSE
NC score	0.717684 (rank : 57)	θ value	2.44474e-05 (rank : 74)
Query Neighborhood Hits	270	Target Neighborhood Hits	442	Shared Neighborhood Hits	217
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_HUMAN
NC score	0.717482 (rank : 58)	θ value	4.1701e-05 (rank : 83)
Query Neighborhood Hits	270	Target Neighborhood Hits	428	Shared Neighborhood Hits	212
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

MEGF6_HUMAN
NC score	0.710658 (rank : 59)	θ value	4.76016e-09 (rank : 18)
Query Neighborhood Hits	270	Target Neighborhood Hits	671	Shared Neighborhood Hits	256
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

TRBM_HUMAN
NC score	0.707882 (rank : 60)	θ value	0.0148317 (rank : 146)
Query Neighborhood Hits	270	Target Neighborhood Hits	339	Shared Neighborhood Hits	213
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRBM_MOUSE
NC score	0.706625 (rank : 61)	θ value	0.00134147 (rank : 122)
Query Neighborhood Hits	270	Target Neighborhood Hits	361	Shared Neighborhood Hits	213
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

NOTC1_MOUSE
NC score	0.688288 (rank : 62)	θ value	2.79066e-09 (rank : 16)
Query Neighborhood Hits	270	Target Neighborhood Hits	916	Shared Neighborhood Hits	253
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

EGF_MOUSE
NC score	0.680367 (rank : 63)	θ value	4.1701e-05 (rank : 80)
Query Neighborhood Hits	270	Target Neighborhood Hits	358	Shared Neighborhood Hits	233
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

NOTC2_MOUSE
NC score	0.671879 (rank : 64)	θ value	4.30538e-10 (rank : 10)
Query Neighborhood Hits	270	Target Neighborhood Hits	1069	Shared Neighborhood Hits	254
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

MATN2_HUMAN
NC score	0.671831 (rank : 65)	θ value	2.88788e-06 (rank : 55)
Query Neighborhood Hits	270	Target Neighborhood Hits	365	Shared Neighborhood Hits	200
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

NOTC3_MOUSE
NC score	0.671310 (rank : 66)	θ value	6.64225e-11 (rank : 8)
Query Neighborhood Hits	270	Target Neighborhood Hits	975	Shared Neighborhood Hits	255
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_HUMAN
NC score	0.669831 (rank : 67)	θ value	3.64472e-09 (rank : 17)
Query Neighborhood Hits	270	Target Neighborhood Hits	1062	Shared Neighborhood Hits	252
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC2_HUMAN
NC score	0.668473 (rank : 68)	θ value	4.76016e-09 (rank : 21)
Query Neighborhood Hits	270	Target Neighborhood Hits	1113	Shared Neighborhood Hits	254
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC1_HUMAN
NC score	0.666952 (rank : 69)	θ value	1.53129e-07 (rank : 41)
Query Neighborhood Hits	270	Target Neighborhood Hits	906	Shared Neighborhood Hits	249
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NID2_MOUSE
NC score	0.664973 (rank : 70)	θ value	9.29e-05 (rank : 90)
Query Neighborhood Hits	270	Target Neighborhood Hits	338	Shared Neighborhood Hits	211
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

MATN2_MOUSE
NC score	0.663267 (rank : 71)	θ value	0.00035302 (rank : 106)
Query Neighborhood Hits	270	Target Neighborhood Hits	356	Shared Neighborhood Hits	200
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

NID2_HUMAN
NC score	0.659651 (rank : 72)	θ value	0.000786445 (rank : 112)
Query Neighborhood Hits	270	Target Neighborhood Hits	456	Shared Neighborhood Hits	215
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

WIF1_HUMAN
NC score	0.658261 (rank : 73)	θ value	4.92598e-06 (rank : 60)
Query Neighborhood Hits	270	Target Neighborhood Hits	392	Shared Neighborhood Hits	213
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

EGF_HUMAN
NC score	0.656661 (rank : 74)	θ value	0.00020696 (rank : 95)
Query Neighborhood Hits	270	Target Neighborhood Hits	343	Shared Neighborhood Hits	221
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

NOTC4_HUMAN
NC score	0.656051 (rank : 75)	θ value	5.62301e-10 (rank : 11)
Query Neighborhood Hits	270	Target Neighborhood Hits	905	Shared Neighborhood Hits	252
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC4_MOUSE
NC score	0.654741 (rank : 76)	θ value	5.26297e-08 (rank : 35)
Query Neighborhood Hits	270	Target Neighborhood Hits	872	Shared Neighborhood Hits	252
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

SUSD1_HUMAN
NC score	0.654407 (rank : 77)	θ value	0.62314 (rank : 200)
Query Neighborhood Hits	270	Target Neighborhood Hits	285	Shared Neighborhood Hits	190
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

NID1_HUMAN
NC score	0.653997 (rank : 78)	θ value	3.19293e-05 (rank : 79)
Query Neighborhood Hits	270	Target Neighborhood Hits	329	Shared Neighborhood Hits	205
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

CUBN_HUMAN
NC score	0.652842 (rank : 79)	θ value	6.43352e-06 (rank : 63)
Query Neighborhood Hits	270	Target Neighborhood Hits	482	Shared Neighborhood Hits	240
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CUBN_MOUSE
NC score	0.652820 (rank : 80)	θ value	0.000270298 (rank : 98)
Query Neighborhood Hits	270	Target Neighborhood Hits	477	Shared Neighborhood Hits	247
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

NID1_MOUSE
NC score	0.652163 (rank : 81)	θ value	0.000270298 (rank : 100)
Query Neighborhood Hits	270	Target Neighborhood Hits	335	Shared Neighborhood Hits	202
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

WIF1_MOUSE
NC score	0.650435 (rank : 82)	θ value	4.92598e-06 (rank : 61)
Query Neighborhood Hits	270	Target Neighborhood Hits	393	Shared Neighborhood Hits	207
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

PROZ_MOUSE
NC score	0.635025 (rank : 83)	θ value	1.63604e-09 (rank : 13)
Query Neighborhood Hits	270	Target Neighborhood Hits	410	Shared Neighborhood Hits	218
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

UROM_HUMAN
NC score	0.632290 (rank : 84)	θ value	0.0330416 (rank : 155)
Query Neighborhood Hits	270	Target Neighborhood Hits	284	Shared Neighborhood Hits	201
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

PROZ_HUMAN
NC score	0.625810 (rank : 85)	θ value	8.11959e-09 (rank : 24)
Query Neighborhood Hits	270	Target Neighborhood Hits	422	Shared Neighborhood Hits	224
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

UROM_MOUSE
NC score	0.621117 (rank : 86)	θ value	0.163984 (rank : 180)
Query Neighborhood Hits	270	Target Neighborhood Hits	276	Shared Neighborhood Hits	194
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

CD248_MOUSE
NC score	0.620763 (rank : 87)	θ value	0.00665767 (rank : 130)
Query Neighborhood Hits	270	Target Neighborhood Hits	578	Shared Neighborhood Hits	194
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD248_HUMAN
NC score	0.606582 (rank : 88)	θ value	0.00509761 (rank : 127)
Query Neighborhood Hits	270	Target Neighborhood Hits	679	Shared Neighborhood Hits	197
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CREL1_MOUSE
NC score	0.606221 (rank : 89)	θ value	0.00102713 (rank : 115)
Query Neighborhood Hits	270	Target Neighborhood Hits	524	Shared Neighborhood Hits	200
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

MATN4_HUMAN
NC score	0.603380 (rank : 90)	θ value	9.29e-05 (rank : 88)
Query Neighborhood Hits	270	Target Neighborhood Hits	287	Shared Neighborhood Hits	190
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

CREL1_HUMAN
NC score	0.599767 (rank : 91)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	270	Target Neighborhood Hits	441	Shared Neighborhood Hits	198
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

MATN3_MOUSE
NC score	0.596653 (rank : 92)	θ value	0.00665767 (rank : 131)
Query Neighborhood Hits	270	Target Neighborhood Hits	261	Shared Neighborhood Hits	181
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

STAB2_HUMAN
NC score	0.596301 (rank : 93)	θ value	0.0961366 (rank : 167)
Query Neighborhood Hits	270	Target Neighborhood Hits	534	Shared Neighborhood Hits	226
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

STAB1_HUMAN
NC score	0.595348 (rank : 94)	θ value	0.000786445 (rank : 113)
Query Neighborhood Hits	270	Target Neighborhood Hits	546	Shared Neighborhood Hits	228
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

EMR1_HUMAN
NC score	0.593697 (rank : 95)	θ value	0.0148317 (rank : 142)
Query Neighborhood Hits	270	Target Neighborhood Hits	382	Shared Neighborhood Hits	198
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EMR2_HUMAN
NC score	0.592338 (rank : 96)	θ value	0.00102713 (rank : 116)
Query Neighborhood Hits	270	Target Neighborhood Hits	345	Shared Neighborhood Hits	202
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

STAB1_MOUSE
NC score	0.591279 (rank : 97)	θ value	0.00228821 (rank : 125)
Query Neighborhood Hits	270	Target Neighborhood Hits	566	Shared Neighborhood Hits	233
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

MATN3_HUMAN
NC score	0.588496 (rank : 98)	θ value	0.0252991 (rank : 152)
Query Neighborhood Hits	270	Target Neighborhood Hits	268	Shared Neighborhood Hits	181
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

LRP1B_MOUSE
NC score	0.586686 (rank : 99)	θ value	0.000461057 (rank : 107)
Query Neighborhood Hits	270	Target Neighborhood Hits	606	Shared Neighborhood Hits	254
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1B_HUMAN
NC score	0.586528 (rank : 100)	θ value	0.00035302 (rank : 105)
Query Neighborhood Hits	270	Target Neighborhood Hits	602	Shared Neighborhood Hits	255
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1_HUMAN
NC score	0.583691 (rank : 101)	θ value	5.44631e-05 (rank : 86)
Query Neighborhood Hits	270	Target Neighborhood Hits	617	Shared Neighborhood Hits	255
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

STAB2_MOUSE
NC score	0.581961 (rank : 102)	θ value	5.27518 (rank : 250)
Query Neighborhood Hits	270	Target Neighborhood Hits	528	Shared Neighborhood Hits	225
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

CD97_HUMAN
NC score	0.581568 (rank : 103)	θ value	0.00175202 (rank : 123)
Query Neighborhood Hits	270	Target Neighborhood Hits	353	Shared Neighborhood Hits	201
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

EMR1_MOUSE
NC score	0.573883 (rank : 104)	θ value	0.0252991 (rank : 150)
Query Neighborhood Hits	270	Target Neighborhood Hits	349	Shared Neighborhood Hits	199
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EDIL3_HUMAN
NC score	0.567021 (rank : 105)	θ value	0.00035302 (rank : 102)
Query Neighborhood Hits	270	Target Neighborhood Hits	292	Shared Neighborhood Hits	196
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
NC score	0.564915 (rank : 106)	θ value	0.000602161 (rank : 108)
Query Neighborhood Hits	270	Target Neighborhood Hits	317	Shared Neighborhood Hits	201
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

MATN4_MOUSE
NC score	0.564456 (rank : 107)	θ value	0.47712 (rank : 197)
Query Neighborhood Hits	270	Target Neighborhood Hits	277	Shared Neighborhood Hits	180
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

SREC_HUMAN
NC score	0.563028 (rank : 108)	θ value	0.000602161 (rank : 110)
Query Neighborhood Hits	270	Target Neighborhood Hits	645	Shared Neighborhood Hits	213
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

SREC2_MOUSE
NC score	0.559909 (rank : 109)	θ value	0.00134147 (rank : 121)
Query Neighborhood Hits	270	Target Neighborhood Hits	605	Shared Neighborhood Hits	211
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

MEGF8_MOUSE
NC score	0.557146 (rank : 110)	θ value	9.29e-05 (rank : 89)
Query Neighborhood Hits	270	Target Neighborhood Hits	520	Shared Neighborhood Hits	228
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_HUMAN
NC score	0.554390 (rank : 111)	θ value	0.000270298 (rank : 99)
Query Neighborhood Hits	270	Target Neighborhood Hits	528	Shared Neighborhood Hits	224
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

SREC2_HUMAN
NC score	0.547435 (rank : 112)	θ value	0.000270298 (rank : 101)
Query Neighborhood Hits	270	Target Neighborhood Hits	645	Shared Neighborhood Hits	208
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

LRP2_HUMAN
NC score	0.546631 (rank : 113)	θ value	4.92598e-06 (rank : 58)
Query Neighborhood Hits	270	Target Neighborhood Hits	573	Shared Neighborhood Hits	245
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

TSP4_HUMAN
NC score	0.544555 (rank : 114)	θ value	0.279714 (rank : 191)
Query Neighborhood Hits	270	Target Neighborhood Hits	277	Shared Neighborhood Hits	195
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_MOUSE
NC score	0.544415 (rank : 115)	θ value	1.06291 (rank : 213)
Query Neighborhood Hits	270	Target Neighborhood Hits	276	Shared Neighborhood Hits	195
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

SLIT1_MOUSE
NC score	0.536897 (rank : 116)	θ value	4.45536e-07 (rank : 45)
Query Neighborhood Hits	270	Target Neighborhood Hits	715	Shared Neighborhood Hits	229
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

SLIT1_HUMAN
NC score	0.532228 (rank : 117)	θ value	2.44474e-05 (rank : 75)
Query Neighborhood Hits	270	Target Neighborhood Hits	700	Shared Neighborhood Hits	230
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

LDLR_HUMAN
NC score	0.525887 (rank : 118)	θ value	0.813845 (rank : 207)
Query Neighborhood Hits	270	Target Neighborhood Hits	375	Shared Neighborhood Hits	214
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

SLIT2_HUMAN
NC score	0.523237 (rank : 119)	θ value	9.92553e-07 (rank : 50)
Query Neighborhood Hits	270	Target Neighborhood Hits	708	Shared Neighborhood Hits	228
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT2_MOUSE
NC score	0.521080 (rank : 120)	θ value	9.92553e-07 (rank : 51)
Query Neighborhood Hits	270	Target Neighborhood Hits	684	Shared Neighborhood Hits	223
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

VLDLR_MOUSE
NC score	0.518167 (rank : 121)	θ value	0.0736092 (rank : 164)
Query Neighborhood Hits	270	Target Neighborhood Hits	360	Shared Neighborhood Hits	210
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

COMP_MOUSE
NC score	0.517753 (rank : 122)	θ value	0.163984 (rank : 178)
Query Neighborhood Hits	270	Target Neighborhood Hits	290	Shared Neighborhood Hits	188
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

VLDLR_HUMAN
NC score	0.515891 (rank : 123)	θ value	0.0736092 (rank : 163)
Query Neighborhood Hits	270	Target Neighborhood Hits	383	Shared Neighborhood Hits	209
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

SLIT3_HUMAN
NC score	0.507973 (rank : 124)	θ value	4.1701e-05 (rank : 84)
Query Neighborhood Hits	270	Target Neighborhood Hits	682	Shared Neighborhood Hits	226
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

LRP8_MOUSE
NC score	0.506802 (rank : 125)	θ value	1.38821 (rank : 220)
Query Neighborhood Hits	270	Target Neighborhood Hits	385	Shared Neighborhood Hits	200
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP4_MOUSE
NC score	0.506277 (rank : 126)	θ value	0.000121331 (rank : 91)
Query Neighborhood Hits	270	Target Neighborhood Hits	351	Shared Neighborhood Hits	202
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

CD97_MOUSE
NC score	0.506153 (rank : 127)	θ value	0.163984 (rank : 176)
Query Neighborhood Hits	270	Target Neighborhood Hits	295	Shared Neighborhood Hits	187
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

SLIT3_MOUSE
NC score	0.505674 (rank : 128)	θ value	0.000602161 (rank : 109)
Query Neighborhood Hits	270	Target Neighborhood Hits	700	Shared Neighborhood Hits	225
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

LRP8_HUMAN
NC score	0.504075 (rank : 129)	θ value	1.81305 (rank : 230)
Query Neighborhood Hits	270	Target Neighborhood Hits	346	Shared Neighborhood Hits	200
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

CSPG2_MOUSE
NC score	0.501919 (rank : 130)	θ value	1.69304e-06 (rank : 52)
Query Neighborhood Hits	270	Target Neighborhood Hits	711	Shared Neighborhood Hits	198
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

COMP_HUMAN
NC score	0.501159 (rank : 131)	θ value	0.0961366 (rank : 166)
Query Neighborhood Hits	270	Target Neighborhood Hits	258	Shared Neighborhood Hits	179
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

LRP4_HUMAN
NC score	0.500708 (rank : 132)	θ value	0.000786445 (rank : 111)
Query Neighborhood Hits	270	Target Neighborhood Hits	355	Shared Neighborhood Hits	206
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

HHIP_HUMAN
NC score	0.500343 (rank : 133)	θ value	0.00134147 (rank : 119)
Query Neighborhood Hits	270	Target Neighborhood Hits	249	Shared Neighborhood Hits	142
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HHIP_MOUSE
NC score	0.498803 (rank : 134)	θ value	0.00228821 (rank : 124)
Query Neighborhood Hits	270	Target Neighborhood Hits	219	Shared Neighborhood Hits	138
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

LDLR_MOUSE
NC score	0.497160 (rank : 135)	θ value	0.47712 (rank : 196)
Query Neighborhood Hits	270	Target Neighborhood Hits	382	Shared Neighborhood Hits	208
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

CSPG2_HUMAN
NC score	0.495846 (rank : 136)	θ value	6.43352e-06 (rank : 62)
Query Neighborhood Hits	270	Target Neighborhood Hits	681	Shared Neighborhood Hits	196
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

TSP3_MOUSE
NC score	0.485778 (rank : 137)	θ value	0.62314 (rank : 201)
Query Neighborhood Hits	270	Target Neighborhood Hits	247	Shared Neighborhood Hits	175
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

CSPG3_MOUSE
NC score	0.476574 (rank : 138)	θ value	0.000270298 (rank : 97)
Query Neighborhood Hits	270	Target Neighborhood Hits	657	Shared Neighborhood Hits	193
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

TSP3_HUMAN
NC score	0.473760 (rank : 139)	θ value	5.27518 (rank : 251)
Query Neighborhood Hits	270	Target Neighborhood Hits	250	Shared Neighborhood Hits	175
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

ELTD1_MOUSE
NC score	0.471084 (rank : 140)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	270	Target Neighborhood Hits	288	Shared Neighborhood Hits	181
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

CSPG3_HUMAN
NC score	0.470346 (rank : 141)	θ value	0.000270298 (rank : 96)
Query Neighborhood Hits	270	Target Neighborhood Hits	676	Shared Neighborhood Hits	187
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

AGRIN_HUMAN
NC score	0.470208 (rank : 142)	θ value	0.813845 (rank : 203)
Query Neighborhood Hits	270	Target Neighborhood Hits	582	Shared Neighborhood Hits	214
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

TENA_HUMAN
NC score	0.444058 (rank : 143)	θ value	θ > 10 (rank : 671)
Query Neighborhood Hits	270	Target Neighborhood Hits	631	Shared Neighborhood Hits	206
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENA_MOUSE
NC score	0.443925 (rank : 144)	θ value	4.03905 (rank : 245)
Query Neighborhood Hits	270	Target Neighborhood Hits	596	Shared Neighborhood Hits	202
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TENX_HUMAN
NC score	0.443677 (rank : 145)	θ value	2.36792 (rank : 231)
Query Neighborhood Hits	270	Target Neighborhood Hits	789	Shared Neighborhood Hits	208
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

HMCN1_HUMAN
NC score	0.433620 (rank : 146)	θ value	3.19293e-05 (rank : 77)
Query Neighborhood Hits	270	Target Neighborhood Hits	983	Shared Neighborhood Hits	216
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

ZAN_MOUSE
NC score	0.426501 (rank : 147)	θ value	θ > 10 (rank : 747)
Query Neighborhood Hits	270	Target Neighborhood Hits	808	Shared Neighborhood Hits	219
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

TDGF1_MOUSE
NC score	0.424902 (rank : 148)	θ value	0.0961366 (rank : 168)
Query Neighborhood Hits	270	Target Neighborhood Hits	146	Shared Neighborhood Hits	116
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

CFC1_HUMAN
NC score	0.417700 (rank : 149)	θ value	0.47712 (rank : 193)
Query Neighborhood Hits	270	Target Neighborhood Hits	148	Shared Neighborhood Hits	123
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

KRA58_HUMAN
NC score	0.413923 (rank : 150)	θ value	0.0431538 (rank : 156)
Query Neighborhood Hits	270	Target Neighborhood Hits	324	Shared Neighborhood Hits	128
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA53_HUMAN
NC score	0.411613 (rank : 151)	θ value	0.62314 (rank : 199)
Query Neighborhood Hits	270	Target Neighborhood Hits	331	Shared Neighborhood Hits	140
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

NAGPA_HUMAN
NC score	0.404014 (rank : 152)	θ value	3.0926 (rank : 233)
Query Neighborhood Hits	270	Target Neighborhood Hits	282	Shared Neighborhood Hits	150
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

FATH_HUMAN
NC score	0.394860 (rank : 153)	θ value	4.0297e-08 (rank : 30)
Query Neighborhood Hits	270	Target Neighborhood Hits	570	Shared Neighborhood Hits	222
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

TDGF1_HUMAN
NC score	0.392627 (rank : 154)	θ value	0.0193708 (rank : 148)
Query Neighborhood Hits	270	Target Neighborhood Hits	132	Shared Neighborhood Hits	112
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

GRN_MOUSE
NC score	0.389828 (rank : 155)	θ value	5.27518 (rank : 247)
Query Neighborhood Hits	270	Target Neighborhood Hits	248	Shared Neighborhood Hits	128
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

TDGF2_HUMAN
NC score	0.389420 (rank : 156)	θ value	0.0148317 (rank : 144)
Query Neighborhood Hits	270	Target Neighborhood Hits	131	Shared Neighborhood Hits	105
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

GRN_HUMAN
NC score	0.387131 (rank : 157)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	270	Target Neighborhood Hits	268	Shared Neighborhood Hits	130
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

KRA51_HUMAN
NC score	0.386193 (rank : 158)	θ value	6.88961 (rank : 253)
Query Neighborhood Hits	270	Target Neighborhood Hits	288	Shared Neighborhood Hits	125
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

NAGPA_MOUSE
NC score	0.380851 (rank : 159)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	270	Target Neighborhood Hits	308	Shared Neighborhood Hits	162
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

MFGM_MOUSE
NC score	0.376731 (rank : 160)	θ value	θ > 10 (rank : 578)
Query Neighborhood Hits	270	Target Neighborhood Hits	233	Shared Neighborhood Hits	154
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

FA10_MOUSE
NC score	0.374410 (rank : 161)	θ value	9.92553e-07 (rank : 49)
Query Neighborhood Hits	270	Target Neighborhood Hits	435	Shared Neighborhood Hits	221
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

LAMA5_MOUSE
NC score	0.373058 (rank : 162)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	270	Target Neighborhood Hits	828	Shared Neighborhood Hits	209
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

MEGF9_HUMAN
NC score	0.371795 (rank : 163)	θ value	θ > 10 (rank : 572)
Query Neighborhood Hits	270	Target Neighborhood Hits	557	Shared Neighborhood Hits	173
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

KR107_HUMAN
NC score	0.368320 (rank : 164)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	270	Target Neighborhood Hits	330	Shared Neighborhood Hits	136
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

CFC1_MOUSE
NC score	0.365470 (rank : 165)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	270	Target Neighborhood Hits	125	Shared Neighborhood Hits	109
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

ELTD1_HUMAN
NC score	0.363344 (rank : 166)	θ value	0.813845 (rank : 205)
Query Neighborhood Hits	270	Target Neighborhood Hits	269	Shared Neighborhood Hits	167
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

FA10_HUMAN
NC score	0.362974 (rank : 167)	θ value	0.00035302 (rank : 103)
Query Neighborhood Hits	270	Target Neighborhood Hits	431	Shared Neighborhood Hits	210
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

LAMA5_HUMAN
NC score	0.360845 (rank : 168)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	270	Target Neighborhood Hits	976	Shared Neighborhood Hits	206
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

KR106_HUMAN
NC score	0.360017 (rank : 169)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	270	Target Neighborhood Hits	347	Shared Neighborhood Hits	138
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR104_HUMAN
NC score	0.355914 (rank : 170)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	270	Target Neighborhood Hits	313	Shared Neighborhood Hits	126
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

LAMA1_MOUSE
NC score	0.354187 (rank : 171)	θ value	0.47712 (rank : 195)
Query Neighborhood Hits	270	Target Neighborhood Hits	838	Shared Neighborhood Hits	203
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

FA9_HUMAN
NC score	0.353551 (rank : 172)	θ value	3.77169e-06 (rank : 56)
Query Neighborhood Hits	270	Target Neighborhood Hits	421	Shared Neighborhood Hits	206
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

LAMB2_HUMAN
NC score	0.352813 (rank : 173)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	270	Target Neighborhood Hits	692	Shared Neighborhood Hits	191
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

PERT_HUMAN
NC score	0.349852 (rank : 174)	θ value	0.0193708 (rank : 147)
Query Neighborhood Hits	270	Target Neighborhood Hits	221	Shared Neighborhood Hits	159
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

LAMA1_HUMAN
NC score	0.349713 (rank : 175)	θ value	1.38821 (rank : 219)
Query Neighborhood Hits	270	Target Neighborhood Hits	804	Shared Neighborhood Hits	197
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

TSP1_MOUSE
NC score	0.348631 (rank : 176)	θ value	θ > 10 (rank : 731)
Query Neighborhood Hits	270	Target Neighborhood Hits	396	Shared Neighborhood Hits	168
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

PROC_MOUSE
NC score	0.348577 (rank : 177)	θ value	5.44631e-05 (rank : 87)
Query Neighborhood Hits	270	Target Neighborhood Hits	426	Shared Neighborhood Hits	213
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

TSP1_HUMAN
NC score	0.347150 (rank : 178)	θ value	θ > 10 (rank : 730)
Query Neighborhood Hits	270	Target Neighborhood Hits	389	Shared Neighborhood Hits	162
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

NTNG2_MOUSE
NC score	0.346412 (rank : 179)	θ value	1.06291 (rank : 212)
Query Neighborhood Hits	270	Target Neighborhood Hits	276	Shared Neighborhood Hits	173
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

TLL1_MOUSE
NC score	0.346228 (rank : 180)	θ value	0.000786445 (rank : 114)
Query Neighborhood Hits	270	Target Neighborhood Hits	237	Shared Neighborhood Hits	157
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

BMP1_MOUSE
NC score	0.342171 (rank : 181)	θ value	0.0961366 (rank : 165)
Query Neighborhood Hits	270	Target Neighborhood Hits	236	Shared Neighborhood Hits	157
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

LAMC2_MOUSE
NC score	0.341971 (rank : 182)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	270	Target Neighborhood Hits	614	Shared Neighborhood Hits	193
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

TLL1_HUMAN
NC score	0.341127 (rank : 183)	θ value	0.00509761 (rank : 129)
Query Neighborhood Hits	270	Target Neighborhood Hits	236	Shared Neighborhood Hits	156
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

LAMB2_MOUSE
NC score	0.340992 (rank : 184)	θ value	8.99809 (rank : 266)
Query Neighborhood Hits	270	Target Neighborhood Hits	722	Shared Neighborhood Hits	186
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

MEGF9_MOUSE
NC score	0.340249 (rank : 185)	θ value	θ > 10 (rank : 573)
Query Neighborhood Hits	270	Target Neighborhood Hits	896	Shared Neighborhood Hits	164
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

BMP1_HUMAN
NC score	0.340248 (rank : 186)	θ value	0.125558 (rank : 172)
Query Neighborhood Hits	270	Target Neighborhood Hits	233	Shared Neighborhood Hits	156
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

KRA57_HUMAN
NC score	0.339213 (rank : 187)	θ value	1.81305 (rank : 228)
Query Neighborhood Hits	270	Target Neighborhood Hits	269	Shared Neighborhood Hits	113
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

TLL2_HUMAN
NC score	0.337324 (rank : 188)	θ value	0.00869519 (rank : 134)
Query Neighborhood Hits	270	Target Neighborhood Hits	241	Shared Neighborhood Hits	156
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

LAMC3_MOUSE
NC score	0.335798 (rank : 189)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	270	Target Neighborhood Hits	624	Shared Neighborhood Hits	189
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

FA7_HUMAN
NC score	0.331608 (rank : 190)	θ value	0.0252991 (rank : 151)
Query Neighborhood Hits	270	Target Neighborhood Hits	404	Shared Neighborhood Hits	204
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

ITB6_MOUSE
NC score	0.330621 (rank : 191)	θ value	8.99809 (rank : 264)
Query Neighborhood Hits	270	Target Neighborhood Hits	341	Shared Neighborhood Hits	181
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

TLL2_MOUSE
NC score	0.330563 (rank : 192)	θ value	0.0736092 (rank : 162)
Query Neighborhood Hits	270	Target Neighborhood Hits	240	Shared Neighborhood Hits	153
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

HABP2_MOUSE
NC score	0.328386 (rank : 193)	θ value	0.279714 (rank : 186)
Query Neighborhood Hits	270	Target Neighborhood Hits	445	Shared Neighborhood Hits	189
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

PERT_MOUSE
NC score	0.327133 (rank : 194)	θ value	0.00665767 (rank : 132)
Query Neighborhood Hits	270	Target Neighborhood Hits	221	Shared Neighborhood Hits	145
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

HABP2_HUMAN
NC score	0.326530 (rank : 195)	θ value	4.03905 (rank : 242)
Query Neighborhood Hits	270	Target Neighborhood Hits	431	Shared Neighborhood Hits	181
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

PROC_HUMAN
NC score	0.326302 (rank : 196)	θ value	4.1701e-05 (rank : 82)
Query Neighborhood Hits	270	Target Neighborhood Hits	406	Shared Neighborhood Hits	210
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

LYAM3_MOUSE
NC score	0.325758 (rank : 197)	θ value	θ > 10 (rank : 563)
Query Neighborhood Hits	270	Target Neighborhood Hits	390	Shared Neighborhood Hits	193
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LAMC3_HUMAN
NC score	0.325473 (rank : 198)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	270	Target Neighborhood Hits	588	Shared Neighborhood Hits	183
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

ATRN_MOUSE
NC score	0.325318 (rank : 199)	θ value	0.125558 (rank : 171)
Query Neighborhood Hits	270	Target Neighborhood Hits	519	Shared Neighborhood Hits	177
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

NTNG2_HUMAN
NC score	0.325253 (rank : 200)	θ value	4.03905 (rank : 244)
Query Neighborhood Hits	270	Target Neighborhood Hits	276	Shared Neighborhood Hits	165
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

CLC14_HUMAN
NC score	0.322574 (rank : 201)	θ value	0.813845 (rank : 204)
Query Neighborhood Hits	270	Target Neighborhood Hits	143	Shared Neighborhood Hits	113
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

ATRN_HUMAN
NC score	0.321218 (rank : 202)	θ value	0.125558 (rank : 170)
Query Neighborhood Hits	270	Target Neighborhood Hits	525	Shared Neighborhood Hits	179
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

CELR2_HUMAN
NC score	0.319994 (rank : 203)	θ value	0.125558 (rank : 173)
Query Neighborhood Hits	270	Target Neighborhood Hits	657	Shared Neighborhood Hits	230
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

PGBM_MOUSE
NC score	0.319949 (rank : 204)	θ value	0.163984 (rank : 179)
Query Neighborhood Hits	270	Target Neighborhood Hits	1073	Shared Neighborhood Hits	216
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

CLC14_MOUSE
NC score	0.319639 (rank : 205)	θ value	4.03905 (rank : 240)
Query Neighborhood Hits	270	Target Neighborhood Hits	120	Shared Neighborhood Hits	110
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

LAMC2_HUMAN
NC score	0.319514 (rank : 206)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	270	Target Neighborhood Hits	715	Shared Neighborhood Hits	176
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

TSP2_HUMAN
NC score	0.319381 (rank : 207)	θ value	θ > 10 (rank : 732)
Query Neighborhood Hits	270	Target Neighborhood Hits	359	Shared Neighborhood Hits	156
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

CELR3_HUMAN
NC score	0.318757 (rank : 208)	θ value	0.00390308 (rank : 126)
Query Neighborhood Hits	270	Target Neighborhood Hits	680	Shared Neighborhood Hits	215
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

LAMC1_MOUSE
NC score	0.318471 (rank : 209)	θ value	0.00134147 (rank : 120)
Query Neighborhood Hits	270	Target Neighborhood Hits	856	Shared Neighborhood Hits	181
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

CRAC1_HUMAN
NC score	0.318329 (rank : 210)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	270	Target Neighborhood Hits	111	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

PGBM_HUMAN
NC score	0.316485 (rank : 211)	θ value	0.279714 (rank : 190)
Query Neighborhood Hits	270	Target Neighborhood Hits	1113	Shared Neighborhood Hits	219
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

ITB3_HUMAN
NC score	0.316454 (rank : 212)	θ value	0.21417 (rank : 181)
Query Neighborhood Hits	270	Target Neighborhood Hits	325	Shared Neighborhood Hits	184
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

LAMA2_HUMAN
NC score	0.316408 (rank : 213)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	270	Target Neighborhood Hits	1092	Shared Neighborhood Hits	191
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

KRA59_HUMAN
NC score	0.316351 (rank : 214)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	270	Target Neighborhood Hits	310	Shared Neighborhood Hits	115
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

CELR1_MOUSE
NC score	0.313625 (rank : 215)	θ value	0.00869519 (rank : 133)
Query Neighborhood Hits	270	Target Neighborhood Hits	617	Shared Neighborhood Hits	218
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

CRAC1_MOUSE
NC score	0.312701 (rank : 216)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	270	Target Neighborhood Hits	112	Shared Neighborhood Hits	93
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

ITB5_MOUSE
NC score	0.312138 (rank : 217)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	270	Target Neighborhood Hits	329	Shared Neighborhood Hits	182
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

CELR3_MOUSE
NC score	0.310399 (rank : 218)	θ value	0.125558 (rank : 174)
Query Neighborhood Hits	270	Target Neighborhood Hits	687	Shared Neighborhood Hits	213
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

LRP6_HUMAN
NC score	0.309820 (rank : 219)	θ value	0.0113563 (rank : 138)
Query Neighborhood Hits	270	Target Neighborhood Hits	235	Shared Neighborhood Hits	130
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LAMB1_MOUSE
NC score	0.308882 (rank : 220)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	270	Target Neighborhood Hits	919	Shared Neighborhood Hits	189
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMC1_HUMAN
NC score	0.308535 (rank : 221)	θ value	0.0736092 (rank : 160)
Query Neighborhood Hits	270	Target Neighborhood Hits	922	Shared Neighborhood Hits	182
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

CELR1_HUMAN
NC score	0.308463 (rank : 222)	θ value	0.0113563 (rank : 135)
Query Neighborhood Hits	270	Target Neighborhood Hits	613	Shared Neighborhood Hits	218
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

TSP2_MOUSE
NC score	0.306899 (rank : 223)	θ value	θ > 10 (rank : 733)
Query Neighborhood Hits	270	Target Neighborhood Hits	352	Shared Neighborhood Hits	156
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

LRP6_MOUSE
NC score	0.306559 (rank : 224)	θ value	0.0113563 (rank : 139)
Query Neighborhood Hits	270	Target Neighborhood Hits	232	Shared Neighborhood Hits	129
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

PCSK5_MOUSE
NC score	0.304980 (rank : 225)	θ value	θ > 10 (rank : 631)
Query Neighborhood Hits	270	Target Neighborhood Hits	613	Shared Neighborhood Hits	186
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

ITB6_HUMAN
NC score	0.304857 (rank : 226)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	270	Target Neighborhood Hits	318	Shared Neighborhood Hits	164
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

UROL1_MOUSE
NC score	0.303490 (rank : 227)	θ value	3.0926 (rank : 236)
Query Neighborhood Hits	270	Target Neighborhood Hits	235	Shared Neighborhood Hits	132
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

KRA54_HUMAN
NC score	0.302764 (rank : 228)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	270	Target Neighborhood Hits	270	Shared Neighborhood Hits	106
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA55_HUMAN
NC score	0.302004 (rank : 229)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	270	Target Neighborhood Hits	257	Shared Neighborhood Hits	104
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KR101_HUMAN
NC score	0.301234 (rank : 230)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	270	Target Neighborhood Hits	261	Shared Neighborhood Hits	103
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

ITB3_MOUSE
NC score	0.299082 (rank : 231)	θ value	0.813845 (rank : 206)
Query Neighborhood Hits	270	Target Neighborhood Hits	319	Shared Neighborhood Hits	175
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

SORL_MOUSE
NC score	0.298708 (rank : 232)	θ value	θ > 10 (rank : 659)
Query Neighborhood Hits	270	Target Neighborhood Hits	439	Shared Neighborhood Hits	149
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

ITB5_HUMAN
NC score	0.296597 (rank : 233)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	270	Target Neighborhood Hits	310	Shared Neighborhood Hits	174
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

LAMA2_MOUSE
NC score	0.296425 (rank : 234)	θ value	4.03905 (rank : 243)
Query Neighborhood Hits	270	Target Neighborhood Hits	1198	Shared Neighborhood Hits	195
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LYAM2_HUMAN
NC score	0.294978 (rank : 235)	θ value	θ > 10 (rank : 560)
Query Neighborhood Hits	270	Target Neighborhood Hits	394	Shared Neighborhood Hits	181
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LAMB1_HUMAN
NC score	0.294875 (rank : 236)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	270	Target Neighborhood Hits	1018	Shared Neighborhood Hits	187
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

MATN1_HUMAN
NC score	0.292960 (rank : 237)	θ value	0.0330416 (rank : 154)
Query Neighborhood Hits	270	Target Neighborhood Hits	191	Shared Neighborhood Hits	136
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

NTNG1_MOUSE
NC score	0.292098 (rank : 238)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	270	Target Neighborhood Hits	246	Shared Neighborhood Hits	151
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

SORL_HUMAN
NC score	0.291621 (rank : 239)	θ value	θ > 10 (rank : 658)
Query Neighborhood Hits	270	Target Neighborhood Hits	440	Shared Neighborhood Hits	147
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

KR171_HUMAN
NC score	0.291185 (rank : 240)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	270	Target Neighborhood Hits	144	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

EMR3_HUMAN
NC score	0.291042 (rank : 241)	θ value	6.88961 (rank : 252)
Query Neighborhood Hits	270	Target Neighborhood Hits	245	Shared Neighborhood Hits	152
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

MATN1_MOUSE
NC score	0.290556 (rank : 242)	θ value	0.0431538 (rank : 157)
Query Neighborhood Hits	270	Target Neighborhood Hits	186	Shared Neighborhood Hits	130
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

FA7_MOUSE
NC score	0.290545 (rank : 243)	θ value	0.0563607 (rank : 158)
Query Neighborhood Hits	270	Target Neighborhood Hits	374	Shared Neighborhood Hits	186
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

LYAM2_MOUSE
NC score	0.290378 (rank : 244)	θ value	θ > 10 (rank : 561)
Query Neighborhood Hits	270	Target Neighborhood Hits	420	Shared Neighborhood Hits	193
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

NTNG1_HUMAN
NC score	0.289881 (rank : 245)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	270	Target Neighborhood Hits	247	Shared Neighborhood Hits	152
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

LAMA3_MOUSE
NC score	0.289565 (rank : 246)	θ value	1.81305 (rank : 229)
Query Neighborhood Hits	270	Target Neighborhood Hits	859	Shared Neighborhood Hits	200
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

PGCB_MOUSE
NC score	0.289244 (rank : 247)	θ value	0.125558 (rank : 175)
Query Neighborhood Hits	270	Target Neighborhood Hits	459	Shared Neighborhood Hits	149
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

LAMB3_MOUSE
NC score	0.288666 (rank : 248)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	270	Target Neighborhood Hits	444	Shared Neighborhood Hits	154
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

ITB7_HUMAN
NC score	0.288603 (rank : 249)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	270	Target Neighborhood Hits	290	Shared Neighborhood Hits	169
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

TENR_MOUSE
NC score	0.288287 (rank : 250)	θ value	θ > 10 (rank : 675)
Query Neighborhood Hits	270	Target Neighborhood Hits	531	Shared Neighborhood Hits	181
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

SSPO_MOUSE
NC score	0.287121 (rank : 251)	θ value	8.99809 (rank : 269)
Query Neighborhood Hits	270	Target Neighborhood Hits	800	Shared Neighborhood Hits	196
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

CELR2_MOUSE
NC score	0.286793 (rank : 252)	θ value	0.163984 (rank : 177)
Query Neighborhood Hits	270	Target Neighborhood Hits	584	Shared Neighborhood Hits	204
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

KR511_HUMAN
NC score	0.286627 (rank : 253)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	270	Target Neighborhood Hits	231	Shared Neighborhood Hits	91
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

ITB7_MOUSE
NC score	0.285483 (rank : 254)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	270	Target Neighborhood Hits	277	Shared Neighborhood Hits	168
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

CRIM1_HUMAN
NC score	0.284923 (rank : 255)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	270	Target Neighborhood Hits	362	Shared Neighborhood Hits	120
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

ITB2_MOUSE
NC score	0.284902 (rank : 256)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	270	Target Neighborhood Hits	326	Shared Neighborhood Hits	172
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

KR102_HUMAN
NC score	0.284427 (rank : 257)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	270	Target Neighborhood Hits	264	Shared Neighborhood Hits	103
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

ITB4_HUMAN
NC score	0.283100 (rank : 258)	θ value	5.27518 (rank : 248)
Query Neighborhood Hits	270	Target Neighborhood Hits	458	Shared Neighborhood Hits	170
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

LRP5_MOUSE
NC score	0.282414 (rank : 259)	θ value	0.279714 (rank : 187)
Query Neighborhood Hits	270	Target Neighborhood Hits	236	Shared Neighborhood Hits	128
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

TENR_HUMAN
NC score	0.282107 (rank : 260)	θ value	θ > 10 (rank : 674)
Query Neighborhood Hits	270	Target Neighborhood Hits	526	Shared Neighborhood Hits	174
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

ITB2_HUMAN
NC score	0.281624 (rank : 261)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	270	Target Neighborhood Hits	282	Shared Neighborhood Hits	161
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

LYAM3_HUMAN
NC score	0.281136 (rank : 262)	θ value	θ > 10 (rank : 562)
Query Neighborhood Hits	270	Target Neighborhood Hits	378	Shared Neighborhood Hits	188
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LRP5_HUMAN
NC score	0.280157 (rank : 263)	θ value	0.365318 (rank : 192)
Query Neighborhood Hits	270	Target Neighborhood Hits	224	Shared Neighborhood Hits	127
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

UROL1_HUMAN
NC score	0.278084 (rank : 264)	θ value	4.03905 (rank : 246)
Query Neighborhood Hits	270	Target Neighborhood Hits	213	Shared Neighborhood Hits	126
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

HGFA_HUMAN
NC score	0.275921 (rank : 265)	θ value	0.0113563 (rank : 137)
Query Neighborhood Hits	270	Target Neighborhood Hits	436	Shared Neighborhood Hits	179
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

KR105_HUMAN
NC score	0.275173 (rank : 266)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	270	Target Neighborhood Hits	271	Shared Neighborhood Hits	107
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

ITB1_MOUSE
NC score	0.270614 (rank : 267)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	270	Target Neighborhood Hits	283	Shared Neighborhood Hits	149
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

PGCB_HUMAN
NC score	0.269899 (rank : 268)	θ value	0.0736092 (rank : 161)
Query Neighborhood Hits	270	Target Neighborhood Hits	478	Shared Neighborhood Hits	140
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

HGFA_MOUSE
NC score	0.267940 (rank : 269)	θ value	1.38821 (rank : 218)
Query Neighborhood Hits	270	Target Neighborhood Hits	419	Shared Neighborhood Hits	180
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

USH2A_MOUSE
NC score	0.263745 (rank : 270)	θ value	θ > 10 (rank : 736)
Query Neighborhood Hits	270	Target Neighborhood Hits	626	Shared Neighborhood Hits	157
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

ITB1_HUMAN
NC score	0.262726 (rank : 271)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	270	Target Neighborhood Hits	298	Shared Neighborhood Hits	148
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

KRA56_HUMAN
NC score	0.259901 (rank : 272)	θ value	6.88961 (rank : 254)
Query Neighborhood Hits	270	Target Neighborhood Hits	207	Shared Neighborhood Hits	93
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

LAMB3_HUMAN
NC score	0.256758 (rank : 273)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	270	Target Neighborhood Hits	461	Shared Neighborhood Hits	136
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMA3_HUMAN
NC score	0.256484 (rank : 274)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	270	Target Neighborhood Hits	760	Shared Neighborhood Hits	174
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

FAT2_HUMAN
NC score	0.254583 (rank : 275)	θ value	0.00035302 (rank : 104)
Query Neighborhood Hits	270	Target Neighborhood Hits	507	Shared Neighborhood Hits	165
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

FRAS1_HUMAN
NC score	0.251731 (rank : 276)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	270	Target Neighborhood Hits	759	Shared Neighborhood Hits	158
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

LAMA4_MOUSE
NC score	0.250658 (rank : 277)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	270	Target Neighborhood Hits	584	Shared Neighborhood Hits	155
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

PHXR5_MOUSE
NC score	0.250446 (rank : 278)	θ value	θ > 10 (rank : 638)
Query Neighborhood Hits	270	Target Neighborhood Hits	102	Shared Neighborhood Hits	76
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

ZAN_HUMAN
NC score	0.249422 (rank : 279)	θ value	θ > 10 (rank : 746)
Query Neighborhood Hits	270	Target Neighborhood Hits	679	Shared Neighborhood Hits	180
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

USH2A_HUMAN
NC score	0.249373 (rank : 280)	θ value	θ > 10 (rank : 735)
Query Neighborhood Hits	270	Target Neighborhood Hits	600	Shared Neighborhood Hits	150
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

FA12_HUMAN
NC score	0.247780 (rank : 281)	θ value	0.47712 (rank : 194)
Query Neighborhood Hits	270	Target Neighborhood Hits	425	Shared Neighborhood Hits	170
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

KRA52_HUMAN
NC score	0.246096 (rank : 282)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	270	Target Neighborhood Hits	236	Shared Neighborhood Hits	94
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KR109_HUMAN
NC score	0.243600 (rank : 283)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	270	Target Neighborhood Hits	226	Shared Neighborhood Hits	92
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

ITB8_HUMAN
NC score	0.239651 (rank : 284)	θ value	8.99809 (rank : 265)
Query Neighborhood Hits	270	Target Neighborhood Hits	280	Shared Neighborhood Hits	148
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

KR108_HUMAN
NC score	0.239180 (rank : 285)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	270	Target Neighborhood Hits	226	Shared Neighborhood Hits	86
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

FRAS1_MOUSE
NC score	0.238336 (rank : 286)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	270	Target Neighborhood Hits	747	Shared Neighborhood Hits	155
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

C1RA_MOUSE
NC score	0.236884 (rank : 287)	θ value	1.06291 (rank : 210)
Query Neighborhood Hits	270	Target Neighborhood Hits	379	Shared Neighborhood Hits	149
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

LAMA4_HUMAN
NC score	0.236790 (rank : 288)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	270	Target Neighborhood Hits	708	Shared Neighborhood Hits	157
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

MUC13_MOUSE
NC score	0.236071 (rank : 289)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	270	Target Neighborhood Hits	447	Shared Neighborhood Hits	130
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

TENN_MOUSE
NC score	0.235529 (rank : 290)	θ value	θ > 10 (rank : 673)
Query Neighborhood Hits	270	Target Neighborhood Hits	484	Shared Neighborhood Hits	163
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

LCE1B_HUMAN
NC score	0.234014 (rank : 291)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	270	Target Neighborhood Hits	58	Shared Neighborhood Hits	30
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

C1RB_MOUSE
NC score	0.233095 (rank : 292)	θ value	1.06291 (rank : 211)
Query Neighborhood Hits	270	Target Neighborhood Hits	380	Shared Neighborhood Hits	149
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

KRA94_HUMAN
NC score	0.231175 (rank : 293)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	270	Target Neighborhood Hits	204	Shared Neighborhood Hits	82
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KR10C_HUMAN
NC score	0.230986 (rank : 294)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	270	Target Neighborhood Hits	219	Shared Neighborhood Hits	88
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KRA98_HUMAN
NC score	0.226032 (rank : 295)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	270	Target Neighborhood Hits	185	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA93_HUMAN
NC score	0.225878 (rank : 296)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	270	Target Neighborhood Hits	203	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

LYAM1_MOUSE
NC score	0.225845 (rank : 297)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	270	Target Neighborhood Hits	332	Shared Neighborhood Hits	149
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

KR10B_HUMAN
NC score	0.222992 (rank : 298)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	270	Target Neighborhood Hits	269	Shared Neighborhood Hits	97
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

PGCA_HUMAN
NC score	0.221568 (rank : 299)	θ value	0.0148317 (rank : 143)
Query Neighborhood Hits	270	Target Neighborhood Hits	821	Shared Neighborhood Hits	144
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

LYAM1_HUMAN
NC score	0.221228 (rank : 300)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	270	Target Neighborhood Hits	315	Shared Neighborhood Hits	144
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

TENN_HUMAN
NC score	0.221025 (rank : 301)	θ value	θ > 10 (rank : 672)
Query Neighborhood Hits	270	Target Neighborhood Hits	453	Shared Neighborhood Hits	160
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

MFGM_HUMAN
NC score	0.220834 (rank : 302)	θ value	0.279714 (rank : 188)
Query Neighborhood Hits	270	Target Neighborhood Hits	150	Shared Neighborhood Hits	107
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

LCE1C_HUMAN
NC score	0.218304 (rank : 303)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	270	Target Neighborhood Hits	65	Shared Neighborhood Hits	30
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

TEFF2_MOUSE
NC score	0.217810 (rank : 304)	θ value	θ > 10 (rank : 670)
Query Neighborhood Hits	270	Target Neighborhood Hits	214	Shared Neighborhood Hits	98
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

KRA13_HUMAN
NC score	0.217128 (rank : 305)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	270	Target Neighborhood Hits	144	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

TEFF2_HUMAN
NC score	0.216054 (rank : 306)	θ value	θ > 10 (rank : 669)
Query Neighborhood Hits	270	Target Neighborhood Hits	211	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

CS1A_MOUSE
NC score	0.215919 (rank : 307)	θ value	0.0148317 (rank : 141)
Query Neighborhood Hits	270	Target Neighborhood Hits	360	Shared Neighborhood Hits	135
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CS1B_MOUSE
NC score	0.215013 (rank : 308)	θ value	0.0113563 (rank : 136)
Query Neighborhood Hits	270	Target Neighborhood Hits	361	Shared Neighborhood Hits	135
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

C1R_HUMAN
NC score	0.214635 (rank : 309)	θ value	4.03905 (rank : 239)
Query Neighborhood Hits	270	Target Neighborhood Hits	364	Shared Neighborhood Hits	138
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

MASP2_HUMAN
NC score	0.214495 (rank : 310)	θ value	0.00509761 (rank : 128)
Query Neighborhood Hits	270	Target Neighborhood Hits	364	Shared Neighborhood Hits	138
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

KR510_HUMAN
NC score	0.212848 (rank : 311)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	270	Target Neighborhood Hits	217	Shared Neighborhood Hits	80
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KRA99_HUMAN
NC score	0.212362 (rank : 312)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	270	Target Neighborhood Hits	173	Shared Neighborhood Hits	73
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

EMR4_MOUSE
NC score	0.211564 (rank : 313)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	270	Target Neighborhood Hits	191	Shared Neighborhood Hits	111
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

MASP2_MOUSE
NC score	0.210063 (rank : 314)	θ value	0.0113563 (rank : 140)
Query Neighborhood Hits	270	Target Neighborhood Hits	382	Shared Neighborhood Hits	142
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MASP1_HUMAN
NC score	0.209852 (rank : 315)	θ value	0.00102713 (rank : 117)
Query Neighborhood Hits	270	Target Neighborhood Hits	369	Shared Neighborhood Hits	138
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

C1S_HUMAN
NC score	0.207461 (rank : 316)	θ value	0.0252991 (rank : 149)
Query Neighborhood Hits	270	Target Neighborhood Hits	359	Shared Neighborhood Hits	140
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

KRA44_HUMAN
NC score	0.206864 (rank : 317)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	270	Target Neighborhood Hits	162	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

MASP1_MOUSE
NC score	0.206413 (rank : 318)	θ value	0.00102713 (rank : 118)
Query Neighborhood Hits	270	Target Neighborhood Hits	364	Shared Neighborhood Hits	139
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

RELN_MOUSE
NC score	0.204429 (rank : 319)	θ value	1.38821 (rank : 225)
Query Neighborhood Hits	270	Target Neighborhood Hits	235	Shared Neighborhood Hits	132
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

LCE1D_HUMAN
NC score	0.204063 (rank : 320)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	270	Target Neighborhood Hits	44	Shared Neighborhood Hits	21
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

MEP1A_MOUSE
NC score	0.203760 (rank : 321)	θ value	θ > 10 (rank : 575)
Query Neighborhood Hits	270	Target Neighborhood Hits	166	Shared Neighborhood Hits	116
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

KRA45_HUMAN
NC score	0.203669 (rank : 322)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	270	Target Neighborhood Hits	194	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

NRX1A_MOUSE
NC score	0.203630 (rank : 323)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	270	Target Neighborhood Hits	164	Shared Neighborhood Hits	101
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_HUMAN
NC score	0.203519 (rank : 324)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	270	Target Neighborhood Hits	170	Shared Neighborhood Hits	102
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX3A_HUMAN
NC score	0.203316 (rank : 325)	θ value	0.279714 (rank : 189)
Query Neighborhood Hits	270	Target Neighborhood Hits	164	Shared Neighborhood Hits	105
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

MMRN1_HUMAN
NC score	0.202105 (rank : 326)	θ value	θ > 10 (rank : 583)
Query Neighborhood Hits	270	Target Neighborhood Hits	636	Shared Neighborhood Hits	125
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

KRA92_HUMAN
NC score	0.200968 (rank : 327)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	270	Target Neighborhood Hits	198	Shared Neighborhood Hits	74
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

NFX1_HUMAN
NC score	0.200138 (rank : 328)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	270	Target Neighborhood Hits	405	Shared Neighborhood Hits	93
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

MEP1A_HUMAN
NC score	0.196745 (rank : 329)	θ value	θ > 10 (rank : 574)
Query Neighborhood Hits	270	Target Neighborhood Hits	162	Shared Neighborhood Hits	116
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

NRX2A_HUMAN
NC score	0.195521 (rank : 330)	θ value	1.38821 (rank : 224)
Query Neighborhood Hits	270	Target Neighborhood Hits	614	Shared Neighborhood Hits	111
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

RELN_HUMAN
NC score	0.194375 (rank : 331)	θ value	3.0926 (rank : 234)
Query Neighborhood Hits	270	Target Neighborhood Hits	233	Shared Neighborhood Hits	130
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

KRA11_HUMAN
NC score	0.194064 (rank : 332)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	270	Target Neighborhood Hits	155	Shared Neighborhood Hits	64
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

VWF_HUMAN
NC score	0.192971 (rank : 333)	θ value	θ > 10 (rank : 741)
Query Neighborhood Hits	270	Target Neighborhood Hits	396	Shared Neighborhood Hits	123
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

KRA47_HUMAN
NC score	0.190494 (rank : 334)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	270	Target Neighborhood Hits	204	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

CORIN_HUMAN
NC score	0.190129 (rank : 335)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	270	Target Neighborhood Hits	453	Shared Neighborhood Hits	148
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

KR414_HUMAN
NC score	0.189863 (rank : 336)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	270	Target Neighborhood Hits	199	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KRA15_HUMAN
NC score	0.188282 (rank : 337)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	270	Target Neighborhood Hits	126	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

MUC5B_HUMAN
NC score	0.187184 (rank : 338)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	270	Target Neighborhood Hits	1020	Shared Neighborhood Hits	158
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

CNTP2_MOUSE
NC score	0.184810 (rank : 339)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	270	Target Neighborhood Hits	194	Shared Neighborhood Hits	112
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

ASTN_HUMAN
NC score	0.183450 (rank : 340)	θ value	8.99809 (rank : 262)
Query Neighborhood Hits	270	Target Neighborhood Hits	105	Shared Neighborhood Hits	80
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

KR10A_HUMAN
NC score	0.183375 (rank : 341)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	270	Target Neighborhood Hits	232	Shared Neighborhood Hits	87
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

CNTP2_HUMAN
NC score	0.181870 (rank : 342)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	270	Target Neighborhood Hits	199	Shared Neighborhood Hits	115
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

VWF_MOUSE
NC score	0.181066 (rank : 343)	θ value	θ > 10 (rank : 742)
Query Neighborhood Hits	270	Target Neighborhood Hits	381	Shared Neighborhood Hits	114
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ST14_MOUSE
NC score	0.180310 (rank : 344)	θ value	θ > 10 (rank : 666)
Query Neighborhood Hits	270	Target Neighborhood Hits	419	Shared Neighborhood Hits	146
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

TPA_MOUSE
NC score	0.179762 (rank : 345)	θ value	1.38821 (rank : 226)
Query Neighborhood Hits	270	Target Neighborhood Hits	335	Shared Neighborhood Hits	135
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

ASTN_MOUSE
NC score	0.179374 (rank : 346)	θ value	8.99809 (rank : 263)
Query Neighborhood Hits	270	Target Neighborhood Hits	98	Shared Neighborhood Hits	78
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

ST14_HUMAN
NC score	0.178820 (rank : 347)	θ value	θ > 10 (rank : 665)
Query Neighborhood Hits	270	Target Neighborhood Hits	409	Shared Neighborhood Hits	141
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

TPA_HUMAN
NC score	0.178781 (rank : 348)	θ value	0.813845 (rank : 209)
Query Neighborhood Hits	270	Target Neighborhood Hits	324	Shared Neighborhood Hits	137
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

LCE1E_HUMAN
NC score	0.176795 (rank : 349)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	270	Target Neighborhood Hits	53	Shared Neighborhood Hits	21
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

NRG4_HUMAN
NC score	0.176463 (rank : 350)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	270	Target Neighborhood Hits	85	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

CORIN_MOUSE
NC score	0.175165 (rank : 351)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	270	Target Neighborhood Hits	451	Shared Neighborhood Hits	146
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

KR412_HUMAN
NC score	0.175158 (rank : 352)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	270	Target Neighborhood Hits	178	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

NRG2_MOUSE
NC score	0.174186 (rank : 353)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	270	Target Neighborhood Hits	392	Shared Neighborhood Hits	97
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

KR103_HUMAN
NC score	0.173989 (rank : 354)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	270	Target Neighborhood Hits	212	Shared Neighborhood Hits	76
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

PGH2_MOUSE
NC score	0.173347 (rank : 355)	θ value	θ > 10 (rank : 637)
Query Neighborhood Hits	270	Target Neighborhood Hits	113	Shared Neighborhood Hits	83
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

TIE1_HUMAN
NC score	0.173241 (rank : 356)	θ value	0.0252991 (rank : 153)
Query Neighborhood Hits	270	Target Neighborhood Hits	1241	Shared Neighborhood Hits	194
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

CNTP4_MOUSE
NC score	0.171437 (rank : 357)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	270	Target Neighborhood Hits	193	Shared Neighborhood Hits	113
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

TECTA_MOUSE
NC score	0.169032 (rank : 358)	θ value	θ > 10 (rank : 668)
Query Neighborhood Hits	270	Target Neighborhood Hits	244	Shared Neighborhood Hits	137
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

SMDF_HUMAN
NC score	0.168741 (rank : 359)	θ value	θ > 10 (rank : 657)
Query Neighborhood Hits	270	Target Neighborhood Hits	117	Shared Neighborhood Hits	65
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

TIE1_MOUSE
NC score	0.168394 (rank : 360)	θ value	0.0563607 (rank : 159)
Query Neighborhood Hits	270	Target Neighborhood Hits	1266	Shared Neighborhood Hits	188
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

NET2_HUMAN
NC score	0.167401 (rank : 361)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	270	Target Neighborhood Hits	194	Shared Neighborhood Hits	105
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

NET2_MOUSE
NC score	0.166592 (rank : 362)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	270	Target Neighborhood Hits	193	Shared Neighborhood Hits	105
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

PGH2_HUMAN
NC score	0.166019 (rank : 363)	θ value	θ > 10 (rank : 636)
Query Neighborhood Hits	270	Target Neighborhood Hits	103	Shared Neighborhood Hits	75
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

LCE1A_HUMAN
NC score	0.165346 (rank : 364)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	270	Target Neighborhood Hits	47	Shared Neighborhood Hits	21
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

CNTP4_HUMAN
NC score	0.165227 (rank : 365)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	270	Target Neighborhood Hits	187	Shared Neighborhood Hits	101
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

NET4_HUMAN
NC score	0.163879 (rank : 366)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	270	Target Neighborhood Hits	191	Shared Neighborhood Hits	104
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

LRP3_HUMAN
NC score	0.162781 (rank : 367)	θ value	θ > 10 (rank : 557)
Query Neighborhood Hits	270	Target Neighborhood Hits	280	Shared Neighborhood Hits	94
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

NRG4_MOUSE
NC score	0.161928 (rank : 368)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	270	Target Neighborhood Hits	79	Shared Neighborhood Hits	51
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

CNTP3_HUMAN
NC score	0.161128 (rank : 369)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	270	Target Neighborhood Hits	195	Shared Neighborhood Hits	102
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

MT4_MOUSE
NC score	0.159809 (rank : 370)	θ value	0.813845 (rank : 208)
Query Neighborhood Hits	270	Target Neighborhood Hits	102	Shared Neighborhood Hits	44
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

PGH1_MOUSE
NC score	0.159378 (rank : 371)	θ value	5.27518 (rank : 249)
Query Neighborhood Hits	270	Target Neighborhood Hits	100	Shared Neighborhood Hits	69
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

NET4_MOUSE
NC score	0.158986 (rank : 372)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	270	Target Neighborhood Hits	180	Shared Neighborhood Hits	105
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

LCE1F_HUMAN
NC score	0.158812 (rank : 373)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	270	Target Neighborhood Hits	48	Shared Neighborhood Hits	20
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

TMG1_HUMAN
NC score	0.157741 (rank : 374)	θ value	θ > 10 (rank : 686)
Query Neighborhood Hits	270	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	O14668	Gene names	PRRG1, PRGP1, TMG1
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 1 precursor (Proline- rich Gla protein 1) (Proline-rich gamma-carboxyglutamic acid protein 1).

NRG1_HUMAN
NC score	0.155710 (rank : 375)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	270	Target Neighborhood Hits	285	Shared Neighborhood Hits	76
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

PCSK5_HUMAN
NC score	0.151108 (rank : 376)	θ value	θ > 10 (rank : 630)
Query Neighborhood Hits	270	Target Neighborhood Hits	291	Shared Neighborhood Hits	116
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

TECTA_HUMAN
NC score	0.150573 (rank : 377)	θ value	θ > 10 (rank : 667)
Query Neighborhood Hits	270	Target Neighborhood Hits	239	Shared Neighborhood Hits	129
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

CNTP1_HUMAN
NC score	0.148495 (rank : 378)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	270	Target Neighborhood Hits	196	Shared Neighborhood Hits	94
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

TIE2_HUMAN
NC score	0.147782 (rank : 379)	θ value	0.0148317 (rank : 145)
Query Neighborhood Hits	270	Target Neighborhood Hits	1192	Shared Neighborhood Hits	187
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

LRP12_MOUSE
NC score	0.144958 (rank : 380)	θ value	θ > 10 (rank : 556)
Query Neighborhood Hits	270	Target Neighborhood Hits	180	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP12_HUMAN
NC score	0.144235 (rank : 381)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	270	Target Neighborhood Hits	205	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

TMG3_HUMAN
NC score	0.143788 (rank : 382)	θ value	θ > 10 (rank : 689)
Query Neighborhood Hits	270	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BZD7, Q8N2N6	Gene names	PRRG3, TMG3
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 3 precursor (Proline- rich Gla protein 3) (Proline-rich gamma-carboxyglutamic acid protein 3).

ADAM8_MOUSE
NC score	0.142614 (rank : 383)	θ value	1.38821 (rank : 217)
Query Neighborhood Hits	270	Target Neighborhood Hits	326	Shared Neighborhood Hits	117
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

TMG3_MOUSE
NC score	0.141517 (rank : 384)	θ value	θ > 10 (rank : 690)
Query Neighborhood Hits	270	Target Neighborhood Hits	30	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PAQ9	Gene names	Prrg3, Gm368, Tmg3
Domain Architecture	No domain graphic available
Description	Transmembrane gamma-carboxyglutamic acid protein 3 precursor (Proline- rich Gla protein 3) (Proline-rich gamma-carboxyglutamic acid protein 3).

TIE2_MOUSE
NC score	0.141046 (rank : 385)	θ value	3.0926 (rank : 235)
Query Neighborhood Hits	270	Target Neighborhood Hits	1204	Shared Neighborhood Hits	188
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

CNTP1_MOUSE
NC score	0.140716 (rank : 386)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	270	Target Neighborhood Hits	183	Shared Neighborhood Hits	90
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

APR3_MOUSE
NC score	0.140293 (rank : 387)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	270	Target Neighborhood Hits	61	Shared Neighborhood Hits	47
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

MUC13_HUMAN
NC score	0.138741 (rank : 388)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	270	Target Neighborhood Hits	164	Shared Neighborhood Hits	80
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

CO7_HUMAN
NC score	0.138489 (rank : 389)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	270	Target Neighborhood Hits	278	Shared Neighborhood Hits	96
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

ADA11_HUMAN
NC score	0.138361 (rank : 390)	θ value	1.38821 (rank : 215)
Query Neighborhood Hits	270	Target Neighborhood Hits	259	Shared Neighborhood Hits	127
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

TMPS6_HUMAN
NC score	0.138046 (rank : 391)	θ value	θ > 10 (rank : 701)
Query Neighborhood Hits	270	Target Neighborhood Hits	338	Shared Neighborhood Hits	112
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

ADA11_MOUSE
NC score	0.137559 (rank : 392)	θ value	1.38821 (rank : 216)
Query Neighborhood Hits	270	Target Neighborhood Hits	263	Shared Neighborhood Hits	128
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

CO6_HUMAN
NC score	0.137336 (rank : 393)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	270	Target Neighborhood Hits	331	Shared Neighborhood Hits	106
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

NRG2_HUMAN
NC score	0.137067 (rank : 394)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	270	Target Neighborhood Hits	419	Shared Neighborhood Hits	86
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

TMPS6_MOUSE
NC score	0.135646 (rank : 395)	θ value	θ > 10 (rank : 702)
Query Neighborhood Hits	270	Target Neighborhood Hits	341	Shared Neighborhood Hits	115
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

MT3_HUMAN
NC score	0.135202 (rank : 396)	θ value	θ > 10 (rank : 586)
Query Neighborhood Hits	270	Target Neighborhood Hits	82	Shared Neighborhood Hits	34
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

MT3_MOUSE
NC score	0.134960 (rank : 397)	θ value	θ > 10 (rank : 587)
Query Neighborhood Hits	270	Target Neighborhood Hits	68	Shared Neighborhood Hits	26
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

LCE3A_HUMAN
NC score	0.134878 (rank : 398)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	270	Target Neighborhood Hits	29	Shared Neighborhood Hits	17
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

PGH1_HUMAN
NC score	0.134820 (rank : 399)	θ value	8.99809 (rank : 267)
Query Neighborhood Hits	270	Target Neighborhood Hits	91	Shared Neighborhood Hits	64
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

ADAM8_HUMAN
NC score	0.134117 (rank : 400)	θ value	0.125558 (rank : 169)
Query Neighborhood Hits	270	Target Neighborhood Hits	327	Shared Neighborhood Hits	119
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

VASN_HUMAN
NC score	0.133887 (rank : 401)	θ value	θ > 10 (rank : 737)
Query Neighborhood Hits	270	Target Neighborhood Hits	449	Shared Neighborhood Hits	114
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

RECK_HUMAN
NC score	0.133017 (rank : 402)	θ value	θ > 10 (rank : 649)
Query Neighborhood Hits	270	Target Neighborhood Hits	189	Shared Neighborhood Hits	68
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

MT4_HUMAN
NC score	0.132338 (rank : 403)	θ value	1.38821 (rank : 221)
Query Neighborhood Hits	270	Target Neighborhood Hits	83	Shared Neighborhood Hits	32
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

NET1_HUMAN
NC score	0.131198 (rank : 404)	θ value	θ > 10 (rank : 593)
Query Neighborhood Hits	270	Target Neighborhood Hits	149	Shared Neighborhood Hits	78
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

MEP1B_MOUSE
NC score	0.130361 (rank : 405)	θ value	θ > 10 (rank : 577)
Query Neighborhood Hits	270	Target Neighborhood Hits	127	Shared Neighborhood Hits	76
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

APR3_HUMAN
NC score	0.129740 (rank : 406)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	270	Target Neighborhood Hits	50	Shared Neighborhood Hits	45
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

VASN_MOUSE
NC score	0.129516 (rank : 407)	θ value	θ > 10 (rank : 738)
Query Neighborhood Hits	270	Target Neighborhood Hits	426	Shared Neighborhood Hits	111
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

CD320_HUMAN
NC score	0.129258 (rank : 408)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	270	Target Neighborhood Hits	103	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

ADA19_MOUSE
NC score	0.128243 (rank : 409)	θ value	0.279714 (rank : 184)
Query Neighborhood Hits	270	Target Neighborhood Hits	315	Shared Neighborhood Hits	127
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ADA23_HUMAN
NC score	0.128092 (rank : 410)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	270	Target Neighborhood Hits	235	Shared Neighborhood Hits	120
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA15_MOUSE
NC score	0.126903 (rank : 411)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	270	Target Neighborhood Hits	324	Shared Neighborhood Hits	130
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

KR410_HUMAN
NC score	0.125752 (rank : 412)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	270	Target Neighborhood Hits	156	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

ADA19_HUMAN
NC score	0.125528 (rank : 413)	θ value	0.279714 (rank : 183)
Query Neighborhood Hits	270	Target Neighborhood Hits	381	Shared Neighborhood Hits	119
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

NET1_MOUSE
NC score	0.124953 (rank : 414)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	270	Target Neighborhood Hits	151	Shared Neighborhood Hits	78
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

ADA23_MOUSE
NC score	0.123320 (rank : 415)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	270	Target Neighborhood Hits	245	Shared Neighborhood Hits	130
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

CO8B_MOUSE
NC score	0.122128 (rank : 416)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	270	Target Neighborhood Hits	224	Shared Neighborhood Hits	86
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

UROK_HUMAN
NC score	0.121932 (rank : 417)	θ value	0.21417 (rank : 182)
Query Neighborhood Hits	270	Target Neighborhood Hits	272	Shared Neighborhood Hits	106
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

TMG4_HUMAN
NC score	0.121716 (rank : 418)	θ value	θ > 10 (rank : 691)
Query Neighborhood Hits	270	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BZD6	Gene names	PRRG4, TMG4
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline- rich Gla protein 4) (Proline-rich gamma-carboxyglutamic acid protein 4).

TMG2_MOUSE
NC score	0.121285 (rank : 419)	θ value	θ > 10 (rank : 688)
Query Neighborhood Hits	270	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R182, Q9EQI2	Gene names	Prrg2, N4wbp1
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 2 precursor (Proline- rich Gla protein 2) (Proline-rich gamma-carboxyglutamic acid protein 2) (NEDD4 WW domain-binding protein 1).

EREG_HUMAN
NC score	0.121212 (rank : 420)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	270	Target Neighborhood Hits	73	Shared Neighborhood Hits	44
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

TMG2_HUMAN
NC score	0.121189 (rank : 421)	θ value	θ > 10 (rank : 687)
Query Neighborhood Hits	270	Target Neighborhood Hits	25	Shared Neighborhood Hits	14
SwissProt Accessions	O14669	Gene names	PRRG2, PRGP2, TMG2
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 2 precursor (Proline- rich Gla protein 2) (Proline-rich gamma-carboxyglutamic acid protein 2).

UROK_MOUSE
NC score	0.119240 (rank : 422)	θ value	1.38821 (rank : 227)
Query Neighborhood Hits	270	Target Neighborhood Hits	273	Shared Neighborhood Hits	107
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

TSG6_HUMAN
NC score	0.118765 (rank : 423)	θ value	θ > 10 (rank : 728)
Query Neighborhood Hits	270	Target Neighborhood Hits	91	Shared Neighborhood Hits	34
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
NC score	0.117841 (rank : 424)	θ value	θ > 10 (rank : 729)
Query Neighborhood Hits	270	Target Neighborhood Hits	91	Shared Neighborhood Hits	33
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

KRA42_HUMAN
NC score	0.117812 (rank : 425)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	270	Target Neighborhood Hits	149	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

ESM1_HUMAN
NC score	0.116639 (rank : 426)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	270	Target Neighborhood Hits	110	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

ADA33_HUMAN
NC score	0.116624 (rank : 427)	θ value	0.813845 (rank : 202)
Query Neighborhood Hits	270	Target Neighborhood Hits	264	Shared Neighborhood Hits	111
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

PCSK6_HUMAN
NC score	0.116542 (rank : 428)	θ value	θ > 10 (rank : 632)
Query Neighborhood Hits	270	Target Neighborhood Hits	298	Shared Neighborhood Hits	92
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

ADA33_MOUSE
NC score	0.113333 (rank : 429)	θ value	0.279714 (rank : 185)
Query Neighborhood Hits	270	Target Neighborhood Hits	231	Shared Neighborhood Hits	101
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADAM9_MOUSE
NC score	0.111937 (rank : 430)	θ value	8.99809 (rank : 261)
Query Neighborhood Hits	270	Target Neighborhood Hits	325	Shared Neighborhood Hits	123
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

FSTL3_HUMAN
NC score	0.111800 (rank : 431)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	270	Target Neighborhood Hits	162	Shared Neighborhood Hits	63
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

KR413_HUMAN
NC score	0.111490 (rank : 432)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	270	Target Neighborhood Hits	112	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

CO9_MOUSE
NC score	0.110643 (rank : 433)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	270	Target Neighborhood Hits	153	Shared Neighborhood Hits	71
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

MUC2_HUMAN
NC score	0.110630 (rank : 434)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	270	Target Neighborhood Hits	906	Shared Neighborhood Hits	111
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

TMG4_MOUSE
NC score	0.109758 (rank : 435)	θ value	θ > 10 (rank : 692)
Query Neighborhood Hits	270	Target Neighborhood Hits	24	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BGN6, Q8BM25	Gene names	Prrg4, Tmg4
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline- rich Gla protein 4) (Proline-rich gamma-carboxyglutamic acid protein 4).

LRP10_MOUSE
NC score	0.108954 (rank : 436)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	270	Target Neighborhood Hits	169	Shared Neighborhood Hits	57
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LCE2C_HUMAN
NC score	0.108569 (rank : 437)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	270	Target Neighborhood Hits	53	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

BMPER_MOUSE
NC score	0.107088 (rank : 438)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	270	Target Neighborhood Hits	194	Shared Neighborhood Hits	68
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

FSTL3_MOUSE
NC score	0.106749 (rank : 439)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	270	Target Neighborhood Hits	152	Shared Neighborhood Hits	60
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

MFRP_HUMAN
NC score	0.106582 (rank : 440)	θ value	θ > 10 (rank : 579)
Query Neighborhood Hits	270	Target Neighborhood Hits	165	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

LRP10_HUMAN
NC score	0.106049 (rank : 441)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	270	Target Neighborhood Hits	197	Shared Neighborhood Hits	56
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

CO9_HUMAN
NC score	0.105788 (rank : 442)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	270	Target Neighborhood Hits	147	Shared Neighborhood Hits	69
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

WFDC3_HUMAN
NC score	0.105497 (rank : 443)	θ value	θ > 10 (rank : 743)
Query Neighborhood Hits	270	Target Neighborhood Hits	138	Shared Neighborhood Hits	47
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

RECK_MOUSE
NC score	0.103586 (rank : 444)	θ value	θ > 10 (rank : 650)
Query Neighborhood Hits	270	Target Neighborhood Hits	158	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

ADAM9_HUMAN
NC score	0.103267 (rank : 445)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	270	Target Neighborhood Hits	243	Shared Neighborhood Hits	110
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

ADA15_HUMAN
NC score	0.102845 (rank : 446)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	270	Target Neighborhood Hits	288	Shared Neighborhood Hits	117
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

CFAI_MOUSE
NC score	0.102704 (rank : 447)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	270	Target Neighborhood Hits	290	Shared Neighborhood Hits	66
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

TMPS7_HUMAN
NC score	0.102583 (rank : 448)	θ value	θ > 10 (rank : 703)
Query Neighborhood Hits	270	Target Neighborhood Hits	275	Shared Neighborhood Hits	71
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

BMPER_HUMAN
NC score	0.102323 (rank : 449)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

CFAI_HUMAN
NC score	0.101836 (rank : 450)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	270	Target Neighborhood Hits	289	Shared Neighborhood Hits	60
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

TMPS7_MOUSE
NC score	0.101043 (rank : 451)	θ value	θ > 10 (rank : 704)
Query Neighborhood Hits	270	Target Neighborhood Hits	275	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

LCE4A_HUMAN
NC score	0.101004 (rank : 452)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	270	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

ADA18_MOUSE
NC score	0.099627 (rank : 453)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	270	Target Neighborhood Hits	227	Shared Neighborhood Hits	94
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ADA10_HUMAN
NC score	0.099406 (rank : 454)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	270	Target Neighborhood Hits	189	Shared Neighborhood Hits	76
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

MFRP_MOUSE
NC score	0.099248 (rank : 455)	θ value	θ > 10 (rank : 580)
Query Neighborhood Hits	270	Target Neighborhood Hits	166	Shared Neighborhood Hits	42
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

TNR25_HUMAN
NC score	0.098446 (rank : 456)	θ value	θ > 10 (rank : 713)
Query Neighborhood Hits	270	Target Neighborhood Hits	172	Shared Neighborhood Hits	50
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

ADA17_HUMAN
NC score	0.098442 (rank : 457)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	270	Target Neighborhood Hits	223	Shared Neighborhood Hits	82
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ADAM7_HUMAN
NC score	0.098269 (rank : 458)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	270	Target Neighborhood Hits	221	Shared Neighborhood Hits	100
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

NETO1_HUMAN
NC score	0.097050 (rank : 459)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	270	Target Neighborhood Hits	110	Shared Neighborhood Hits	41
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
NC score	0.096917 (rank : 460)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	270	Target Neighborhood Hits	109	Shared Neighborhood Hits	41
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

ADA30_HUMAN
NC score	0.096542 (rank : 461)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	270	Target Neighborhood Hits	391	Shared Neighborhood Hits	92
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

LORI_MOUSE
NC score	0.095745 (rank : 462)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	270	Target Neighborhood Hits	47	Shared Neighborhood Hits	16
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

MCSP_MOUSE
NC score	0.095295 (rank : 463)	θ value	θ > 10 (rank : 571)
Query Neighborhood Hits	270	Target Neighborhood Hits	108	Shared Neighborhood Hits	30
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

ADA32_HUMAN
NC score	0.094684 (rank : 464)	θ value	0.62314 (rank : 198)
Query Neighborhood Hits	270	Target Neighborhood Hits	216	Shared Neighborhood Hits	106
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ENTK_MOUSE
NC score	0.094503 (rank : 465)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	270	Target Neighborhood Hits	338	Shared Neighborhood Hits	65
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

CO8B_HUMAN
NC score	0.094482 (rank : 466)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	270	Target Neighborhood Hits	199	Shared Neighborhood Hits	66
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

VEGFC_HUMAN
NC score	0.094027 (rank : 467)	θ value	θ > 10 (rank : 739)
Query Neighborhood Hits	270	Target Neighborhood Hits	128	Shared Neighborhood Hits	60
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

NETO2_MOUSE
NC score	0.093910 (rank : 468)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	270	Target Neighborhood Hits	113	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_HUMAN
NC score	0.093541 (rank : 469)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	270	Target Neighborhood Hits	109	Shared Neighborhood Hits	38
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

SHBG_MOUSE
NC score	0.093537 (rank : 470)	θ value	θ > 10 (rank : 656)
Query Neighborhood Hits	270	Target Neighborhood Hits	50	Shared Neighborhood Hits	23
SwissProt Accessions	P97497	Gene names	Shbg
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP).

ADA21_MOUSE
NC score	0.093294 (rank : 471)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	270	Target Neighborhood Hits	172	Shared Neighborhood Hits	90
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

SHBG_HUMAN
NC score	0.093113 (rank : 472)	θ value	θ > 10 (rank : 655)
Query Neighborhood Hits	270	Target Neighborhood Hits	45	Shared Neighborhood Hits	19
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

THRB_HUMAN
NC score	0.093050 (rank : 473)	θ value	θ > 10 (rank : 680)
Query Neighborhood Hits	270	Target Neighborhood Hits	196	Shared Neighborhood Hits	32
SwissProt Accessions	P00734	Gene names	F2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

ADAM2_MOUSE
NC score	0.092851 (rank : 474)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	270	Target Neighborhood Hits	209	Shared Neighborhood Hits	96
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

EPGN_MOUSE
NC score	0.091982 (rank : 475)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	270	Target Neighborhood Hits	63	Shared Neighborhood Hits	37
SwissProt Accessions	Q924X1, Q8CEX5	Gene names	Epgn
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

PCOC1_MOUSE
NC score	0.091535 (rank : 476)	θ value	θ > 10 (rank : 627)
Query Neighborhood Hits	270	Target Neighborhood Hits	100	Shared Neighborhood Hits	23
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

LCE2D_HUMAN
NC score	0.091439 (rank : 477)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	270	Target Neighborhood Hits	50	Shared Neighborhood Hits	11
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

NRP2_HUMAN
NC score	0.091385 (rank : 478)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	270	Target Neighborhood Hits	120	Shared Neighborhood Hits	29
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

THRB_MOUSE
NC score	0.091188 (rank : 479)	θ value	θ > 10 (rank : 681)
Query Neighborhood Hits	270	Target Neighborhood Hits	195	Shared Neighborhood Hits	32
SwissProt Accessions	P19221	Gene names	F2, Cf2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

GP126_HUMAN
NC score	0.091127 (rank : 480)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	270	Target Neighborhood Hits	187	Shared Neighborhood Hits	35
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

ADA10_MOUSE
NC score	0.090918 (rank : 481)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	270	Target Neighborhood Hits	194	Shared Neighborhood Hits	68
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

PCOC2_HUMAN
NC score	0.090599 (rank : 482)	θ value	θ > 10 (rank : 628)
Query Neighborhood Hits	270	Target Neighborhood Hits	73	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

NRP2_MOUSE
NC score	0.090573 (rank : 483)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	270	Target Neighborhood Hits	113	Shared Neighborhood Hits	28
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

FST_MOUSE
NC score	0.090473 (rank : 484)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	270	Target Neighborhood Hits	146	Shared Neighborhood Hits	46
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

ADA12_HUMAN
NC score	0.090384 (rank : 485)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	270	Target Neighborhood Hits	224	Shared Neighborhood Hits	99
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA22_MOUSE
NC score	0.089627 (rank : 486)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	270	Target Neighborhood Hits	225	Shared Neighborhood Hits	94
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ENTK_HUMAN
NC score	0.089036 (rank : 487)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	270	Target Neighborhood Hits	310	Shared Neighborhood Hits	61
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

PCOC1_HUMAN
NC score	0.088900 (rank : 488)	θ value	θ > 10 (rank : 626)
Query Neighborhood Hits	270	Target Neighborhood Hits	146	Shared Neighborhood Hits	21
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

MKS3_HUMAN
NC score	0.088872 (rank : 489)	θ value	θ > 10 (rank : 581)
Query Neighborhood Hits	270	Target Neighborhood Hits	79	Shared Neighborhood Hits	40
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

ADAM2_HUMAN
NC score	0.088808 (rank : 490)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	82
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

PCOC2_MOUSE
NC score	0.088631 (rank : 491)	θ value	θ > 10 (rank : 629)
Query Neighborhood Hits	270	Target Neighborhood Hits	73	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

HPT_HUMAN
NC score	0.088136 (rank : 492)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	270	Target Neighborhood Hits	184	Shared Neighborhood Hits	29
SwissProt Accessions	P00738, P00737, Q2PP15, Q3B7J0, Q6LBY9	Gene names	HP
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

ADM1A_MOUSE
NC score	0.087885 (rank : 493)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	270	Target Neighborhood Hits	230	Shared Neighborhood Hits	104
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

MEP1B_HUMAN
NC score	0.087852 (rank : 494)	θ value	θ > 10 (rank : 576)
Query Neighborhood Hits	270	Target Neighborhood Hits	98	Shared Neighborhood Hits	51
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

CSMD1_MOUSE
NC score	0.086991 (rank : 495)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	270	Target Neighborhood Hits	193	Shared Neighborhood Hits	55
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD3_HUMAN
NC score	0.086799 (rank : 496)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	270	Target Neighborhood Hits	199	Shared Neighborhood Hits	51
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

BTC_MOUSE
NC score	0.086611 (rank : 497)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	270	Target Neighborhood Hits	67	Shared Neighborhood Hits	41
SwissProt Accessions	Q05928	Gene names	Btc, Bcn
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

HPTR_HUMAN
NC score	0.086496 (rank : 498)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	270	Target Neighborhood Hits	166	Shared Neighborhood Hits	28
SwissProt Accessions	P00739, Q7LE20, Q92658, Q92659, Q9ULB0	Gene names	HPR
Domain Architecture
Description	Haptoglobin-related protein precursor.

CO8A_HUMAN
NC score	0.086315 (rank : 499)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	270	Target Neighborhood Hits	200	Shared Neighborhood Hits	71
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CSMD1_HUMAN
NC score	0.086177 (rank : 500)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	48
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

NRP1_MOUSE
NC score	0.086164 (rank : 501)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	270	Target Neighborhood Hits	120	Shared Neighborhood Hits	25
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

CUZD1_HUMAN
NC score	0.086101 (rank : 502)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	270	Target Neighborhood Hits	89	Shared Neighborhood Hits	26
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

ADA28_HUMAN
NC score	0.085882 (rank : 503)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	270	Target Neighborhood Hits	244	Shared Neighborhood Hits	101
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ESM1_MOUSE
NC score	0.085809 (rank : 504)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	270	Target Neighborhood Hits	107	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

HPT_MOUSE
NC score	0.085340 (rank : 505)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	270	Target Neighborhood Hits	178	Shared Neighborhood Hits	28
SwissProt Accessions	Q61646	Gene names	Hp
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

NRP1_HUMAN
NC score	0.085167 (rank : 506)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	270	Target Neighborhood Hits	119	Shared Neighborhood Hits	26
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

ADA18_HUMAN
NC score	0.084901 (rank : 507)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	270	Target Neighborhood Hits	184	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

ADA22_HUMAN
NC score	0.084640 (rank : 508)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	270	Target Neighborhood Hits	211	Shared Neighborhood Hits	87
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ADA28_MOUSE
NC score	0.084531 (rank : 509)	θ value	8.99809 (rank : 260)
Query Neighborhood Hits	270	Target Neighborhood Hits	241	Shared Neighborhood Hits	98
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ADA21_HUMAN
NC score	0.084388 (rank : 510)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	270	Target Neighborhood Hits	181	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

VEGFC_MOUSE
NC score	0.084278 (rank : 511)	θ value	θ > 10 (rank : 740)
Query Neighborhood Hits	270	Target Neighborhood Hits	119	Shared Neighborhood Hits	59
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

PDGFD_MOUSE
NC score	0.083533 (rank : 512)	θ value	θ > 10 (rank : 634)
Query Neighborhood Hits	270	Target Neighborhood Hits	72	Shared Neighborhood Hits	21
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

CFAB_MOUSE
NC score	0.083332 (rank : 513)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	270	Target Neighborhood Hits	262	Shared Neighborhood Hits	46
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

LCE2B_HUMAN
NC score	0.083236 (rank : 514)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	270	Target Neighborhood Hits	50	Shared Neighborhood Hits	13
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

HPLN3_MOUSE
NC score	0.082520 (rank : 515)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	270	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	Q80WM5, Q80XX3	Gene names	Hapln3, Lpr3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor (Link protein 3).

HPLN2_MOUSE
NC score	0.082508 (rank : 516)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	270	Target Neighborhood Hits	102	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ESM3	Gene names	Hapln2, Bral1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

CO8A_MOUSE
NC score	0.082224 (rank : 517)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	270	Target Neighborhood Hits	182	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

HPLN2_HUMAN
NC score	0.082033 (rank : 518)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	270	Target Neighborhood Hits	80	Shared Neighborhood Hits	13
SwissProt Accessions	Q9GZV7	Gene names	HAPLN2, BRAL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

FST_HUMAN
NC score	0.081992 (rank : 519)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	270	Target Neighborhood Hits	129	Shared Neighborhood Hits	36
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

CUZD1_MOUSE
NC score	0.081877 (rank : 520)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	270	Target Neighborhood Hits	91	Shared Neighborhood Hits	25
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

LCE2A_HUMAN
NC score	0.081602 (rank : 521)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	270	Target Neighborhood Hits	50	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

EPGN_HUMAN
NC score	0.081435 (rank : 522)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	270	Target Neighborhood Hits	59	Shared Neighborhood Hits	33
SwissProt Accessions	Q6UW88	Gene names	EPGN
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

HPLN3_HUMAN
NC score	0.081423 (rank : 523)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	270	Target Neighborhood Hits	70	Shared Neighborhood Hits	11
SwissProt Accessions	Q96S86	Gene names	HAPLN3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor.

CSMD2_HUMAN
NC score	0.081190 (rank : 524)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	270	Target Neighborhood Hits	188	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

ADA25_MOUSE
NC score	0.080978 (rank : 525)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	270	Target Neighborhood Hits	213	Shared Neighborhood Hits	85
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

PDGFD_HUMAN
NC score	0.080705 (rank : 526)	θ value	θ > 10 (rank : 633)
Query Neighborhood Hits	270	Target Neighborhood Hits	74	Shared Neighborhood Hits	21
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

HPLN1_HUMAN
NC score	0.079824 (rank : 527)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	270	Target Neighborhood Hits	67	Shared Neighborhood Hits	11
SwissProt Accessions	P10915	Gene names	HAPLN1, CRTL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

HPLN4_HUMAN
NC score	0.079808 (rank : 528)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	270	Target Neighborhood Hits	100	Shared Neighborhood Hits	12
SwissProt Accessions	Q86UW8, Q96PW2	Gene names	HAPLN4, BRAL2, KIAA1926
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2).

HPLN1_MOUSE
NC score	0.079697 (rank : 529)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	270	Target Neighborhood Hits	64	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QUP5, Q9D1G9, Q9Z1X7	Gene names	Hapln1, Crtl1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

HPLN4_MOUSE
NC score	0.079141 (rank : 530)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	270	Target Neighborhood Hits	98	Shared Neighborhood Hits	13
SwissProt Accessions	Q80WM4, Q80XX2	Gene names	Hapln4, Bral2, Lpr4
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2) (Link protein 4).

TNR16_HUMAN
NC score	0.078897 (rank : 531)	θ value	θ > 10 (rank : 711)
Query Neighborhood Hits	270	Target Neighborhood Hits	183	Shared Neighborhood Hits	55
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

IDD_HUMAN
NC score	0.078702 (rank : 532)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	270	Target Neighborhood Hits	127	Shared Neighborhood Hits	32
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

ADM1B_MOUSE
NC score	0.078649 (rank : 533)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	270	Target Neighborhood Hits	236	Shared Neighborhood Hits	90
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

MKS3_MOUSE
NC score	0.078167 (rank : 534)	θ value	θ > 10 (rank : 582)
Query Neighborhood Hits	270	Target Neighborhood Hits	89	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

SEZ6L_HUMAN
NC score	0.077782 (rank : 535)	θ value	θ > 10 (rank : 654)
Query Neighborhood Hits	270	Target Neighborhood Hits	289	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

ADA32_MOUSE
NC score	0.077459 (rank : 536)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	270	Target Neighborhood Hits	219	Shared Neighborhood Hits	90
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

IDD_MOUSE
NC score	0.077458 (rank : 537)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	270	Target Neighborhood Hits	151	Shared Neighborhood Hits	31
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

TMPS9_HUMAN
NC score	0.077015 (rank : 538)	θ value	θ > 10 (rank : 705)
Query Neighborhood Hits	270	Target Neighborhood Hits	276	Shared Neighborhood Hits	51
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

TNR16_MOUSE
NC score	0.076681 (rank : 539)	θ value	θ > 10 (rank : 712)
Query Neighborhood Hits	270	Target Neighborhood Hits	178	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TMPS9_MOUSE
NC score	0.076617 (rank : 540)	θ value	θ > 10 (rank : 706)
Query Neighborhood Hits	270	Target Neighborhood Hits	296	Shared Neighborhood Hits	48
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

ADA17_MOUSE
NC score	0.076077 (rank : 541)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	270	Target Neighborhood Hits	201	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

ADA24_MOUSE
NC score	0.075492 (rank : 542)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	270	Target Neighborhood Hits	230	Shared Neighborhood Hits	88
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

DMBT1_MOUSE
NC score	0.075297 (rank : 543)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	270	Target Neighborhood Hits	134	Shared Neighborhood Hits	27
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

RSPO3_HUMAN
NC score	0.075246 (rank : 544)	θ value	θ > 10 (rank : 651)
Query Neighborhood Hits	270	Target Neighborhood Hits	128	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

DCBD1_MOUSE
NC score	0.075196 (rank : 545)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	270	Target Neighborhood Hits	89	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

ADAM7_MOUSE
NC score	0.074771 (rank : 546)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	270	Target Neighborhood Hits	200	Shared Neighborhood Hits	87
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

TMPS2_MOUSE
NC score	0.074723 (rank : 547)	θ value	θ > 10 (rank : 694)
Query Neighborhood Hits	270	Target Neighborhood Hits	243	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JIQ8, Q9JKC4, Q9QY82	Gene names	Tmprss2
Domain Architecture
Description	Transmembrane protease, serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

DCBD1_HUMAN
NC score	0.073649 (rank : 548)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	270	Target Neighborhood Hits	110	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

ADA12_MOUSE
NC score	0.073457 (rank : 549)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	270	Target Neighborhood Hits	474	Shared Neighborhood Hits	82
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

TNR9_HUMAN
NC score	0.073318 (rank : 550)	θ value	θ > 10 (rank : 716)
Query Neighborhood Hits	270	Target Neighborhood Hits	166	Shared Neighborhood Hits	46
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

CFAB_HUMAN
NC score	0.072694 (rank : 551)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	270	Target Neighborhood Hits	251	Shared Neighborhood Hits	40
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

EREG_MOUSE
NC score	0.072675 (rank : 552)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	270	Target Neighborhood Hits	65	Shared Neighborhood Hits	33
SwissProt Accessions	Q61521, Q7M0A8	Gene names	Ereg
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

TMPS3_MOUSE
NC score	0.072406 (rank : 553)	θ value	θ > 10 (rank : 696)
Query Neighborhood Hits	270	Target Neighborhood Hits	239	Shared Neighborhood Hits	51
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

GP128_MOUSE
NC score	0.071864 (rank : 554)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	270	Target Neighborhood Hits	141	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BM96, Q80T42	Gene names	Gpr128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

DCBD2_HUMAN
NC score	0.071773 (rank : 555)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	270	Target Neighborhood Hits	118	Shared Neighborhood Hits	26
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

PGCA_MOUSE
NC score	0.071671 (rank : 556)	θ value	θ > 10 (rank : 635)
Query Neighborhood Hits	270	Target Neighborhood Hits	643	Shared Neighborhood Hits	23
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

BTC_HUMAN
NC score	0.071470 (rank : 557)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	270	Target Neighborhood Hits	70	Shared Neighborhood Hits	34
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

TGFA_HUMAN
NC score	0.071310 (rank : 558)	θ value	θ > 10 (rank : 678)
Query Neighborhood Hits	270	Target Neighborhood Hits	61	Shared Neighborhood Hits	37
SwissProt Accessions	P01135, Q15577	Gene names	TGFA
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

TMPS2_HUMAN
NC score	0.071149 (rank : 559)	θ value	θ > 10 (rank : 693)
Query Neighborhood Hits	270	Target Neighborhood Hits	252	Shared Neighborhood Hits	48
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

LCE3B_HUMAN
NC score	0.070867 (rank : 560)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	270	Target Neighborhood Hits	47	Shared Neighborhood Hits	20
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

GP128_HUMAN
NC score	0.070722 (rank : 561)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	270	Target Neighborhood Hits	135	Shared Neighborhood Hits	43
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

TMPS3_HUMAN
NC score	0.070401 (rank : 562)	θ value	θ > 10 (rank : 695)
Query Neighborhood Hits	270	Target Neighborhood Hits	245	Shared Neighborhood Hits	47
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

ADA29_HUMAN
NC score	0.070370 (rank : 563)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	270	Target Neighborhood Hits	247	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

TMPS4_HUMAN
NC score	0.069763 (rank : 564)	θ value	θ > 10 (rank : 697)
Query Neighborhood Hits	270	Target Neighborhood Hits	203	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NRS4, Q5XKQ6, Q6UX37, Q9NZA5	Gene names	TMPRSS4, TMPRSS3
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Membrane-type serine protease 2) (MT-SP2).

TMSP8_MOUSE
NC score	0.069248 (rank : 565)	θ value	θ > 10 (rank : 709)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QYZ9, Q91XC4	Gene names	Tmprss8, Disp
Domain Architecture
Description	Transmembrane serine protease 8 precursor (EC 3.4.21.-) (Distal intestinal serine protease).

CO2_MOUSE
NC score	0.068883 (rank : 566)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	270	Target Neighborhood Hits	250	Shared Neighborhood Hits	43
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

DCBD2_MOUSE
NC score	0.068380 (rank : 567)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	270	Target Neighborhood Hits	113	Shared Neighborhood Hits	26
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

KRA24_HUMAN
NC score	0.068248 (rank : 568)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	270	Target Neighborhood Hits	192	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

CTRL_HUMAN
NC score	0.067913 (rank : 569)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	270	Target Neighborhood Hits	179	Shared Neighborhood Hits	28
SwissProt Accessions	P40313	Gene names	CTRL, CTRL1
Domain Architecture
Description	Chymotrypsin-like protease CTRL-1 precursor (EC 3.4.21.-).

CO2_HUMAN
NC score	0.067763 (rank : 570)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	270	Target Neighborhood Hits	258	Shared Neighborhood Hits	42
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

TMPS4_MOUSE
NC score	0.067616 (rank : 571)	θ value	θ > 10 (rank : 698)
Query Neighborhood Hits	270	Target Neighborhood Hits	210	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VCA5	Gene names	Tmprss4, Cap2
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (mCAP2).

TM11D_HUMAN
NC score	0.067561 (rank : 572)	θ value	θ > 10 (rank : 682)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	28
SwissProt Accessions	O60235	Gene names	TMPRSS11D, HAT
Domain Architecture
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

TM11E_HUMAN
NC score	0.067547 (rank : 573)	θ value	θ > 10 (rank : 684)
Query Neighborhood Hits	270	Target Neighborhood Hits	181	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UL52, Q6UW31	Gene names	TMPRSS11E, DESC1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

KLKB1_HUMAN
NC score	0.067480 (rank : 574)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	270	Target Neighborhood Hits	183	Shared Neighborhood Hits	29
SwissProt Accessions	P03952	Gene names	KLKB1, KLK3
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

TM11D_MOUSE
NC score	0.067335 (rank : 575)	θ value	θ > 10 (rank : 683)
Query Neighborhood Hits	270	Target Neighborhood Hits	179	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VHK8, Q7TNX3, Q8VDV1	Gene names	Tmprss11d, Mat
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) (AT) (Adrenal secretory serine protease) (AsP) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

KLKB1_MOUSE
NC score	0.066957 (rank : 576)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	270	Target Neighborhood Hits	177	Shared Neighborhood Hits	28
SwissProt Accessions	P26262	Gene names	Klkb1, Klk3, Pk
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

GNPTA_HUMAN
NC score	0.066935 (rank : 577)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	270	Target Neighborhood Hits	43	Shared Neighborhood Hits	10
SwissProt Accessions	Q3T906, Q3ZQK2, Q6IPW5, Q86TQ2, Q96N13, Q9ULL2	Gene names	GNPTAB, GNPTA, KIAA1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

PRSS8_MOUSE
NC score	0.066881 (rank : 578)	θ value	θ > 10 (rank : 646)
Query Neighborhood Hits	270	Target Neighborhood Hits	177	Shared Neighborhood Hits	29
SwissProt Accessions	Q9ESD1	Gene names	Prss8, Cap1
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) (Channel-activating protease 1) [Contains: Prostasin light chain; Prostasin heavy chain].

PRSS8_HUMAN
NC score	0.066859 (rank : 579)	θ value	θ > 10 (rank : 645)
Query Neighborhood Hits	270	Target Neighborhood Hits	177	Shared Neighborhood Hits	29
SwissProt Accessions	Q16651, Q9UCA3	Gene names	PRSS8
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) [Contains: Prostasin light chain; Prostasin heavy chain].

CTRB1_HUMAN
NC score	0.066671 (rank : 580)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	28
SwissProt Accessions	P17538	Gene names	CTRB1, CTRB
Domain Architecture
Description	Chymotrypsinogen B precursor (EC 3.4.21.1) [Contains: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C].

SPR2D_MOUSE
NC score	0.066639 (rank : 581)	θ value	θ > 10 (rank : 661)
Query Neighborhood Hits	270	Target Neighborhood Hits	61	Shared Neighborhood Hits	14
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

KREM1_MOUSE
NC score	0.066414 (rank : 582)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	270	Target Neighborhood Hits	92	Shared Neighborhood Hits	33
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

CLCR_HUMAN
NC score	0.066076 (rank : 583)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	270	Target Neighborhood Hits	177	Shared Neighborhood Hits	28
SwissProt Accessions	Q99895, O00765, Q9NUH5	Gene names	CTRC, CLCR
Domain Architecture
Description	Caldecrin precursor (EC 3.4.21.2) (Chymotrypsin C).

HEPS_HUMAN
NC score	0.065902 (rank : 584)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	270	Target Neighborhood Hits	178	Shared Neighborhood Hits	29
SwissProt Accessions	P05981	Gene names	HPN, TMPRSS1
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) (Transmembrane protease, serine 1) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

PAPPA_MOUSE
NC score	0.065862 (rank : 585)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	270	Target Neighborhood Hits	153	Shared Neighborhood Hits	47
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

HBEGF_HUMAN
NC score	0.065852 (rank : 586)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	270	Target Neighborhood Hits	61	Shared Neighborhood Hits	35
SwissProt Accessions	Q99075	Gene names	HBEGF, DTR, HEGFL
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF) (Diphtheria toxin receptor) (DT-R).

FA11_HUMAN
NC score	0.065789 (rank : 587)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	270	Target Neighborhood Hits	178	Shared Neighborhood Hits	28
SwissProt Accessions	P03951, Q9Y495	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

TM11E_MOUSE
NC score	0.065719 (rank : 588)	θ value	θ > 10 (rank : 685)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	27
SwissProt Accessions	Q5S248, Q8BM10	Gene names	Tmprss11e, Desc1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

HEPS_MOUSE
NC score	0.065359 (rank : 589)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	270	Target Neighborhood Hits	178	Shared Neighborhood Hits	29
SwissProt Accessions	O35453, Q9CW97	Gene names	Hpn
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

TRYG1_HUMAN
NC score	0.065309 (rank : 590)	θ value	θ > 10 (rank : 726)
Query Neighborhood Hits	270	Target Neighborhood Hits	179	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NRR2, Q96RZ8, Q9C015, Q9NRQ8, Q9UBB2	Gene names	TPSG1, TMT
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

PRS27_HUMAN
NC score	0.065266 (rank : 591)	θ value	θ > 10 (rank : 643)
Query Neighborhood Hits	270	Target Neighborhood Hits	177	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BQR3	Gene names	PRSS27, MPN
Domain Architecture
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin) (Channel-activating protease 2) (CAPH2).

DESC4_MOUSE
NC score	0.065242 (rank : 592)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BZ10, Q8BZ04	Gene names	Desc4
Domain Architecture	No domain graphic available
Description	Serine protease DESC4 precursor (EC 3.4.21.-) [Contains: Serine protease DESC4 non-catalytic chain; Serine protease DESC4 catalytic chain].

PLMN_MOUSE
NC score	0.065187 (rank : 593)	θ value	θ > 10 (rank : 640)
Query Neighborhood Hits	270	Target Neighborhood Hits	208	Shared Neighborhood Hits	33
SwissProt Accessions	P20918, Q8CIS2, Q91WJ5	Gene names	Plg
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

KREM2_HUMAN
NC score	0.065073 (rank : 594)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	270	Target Neighborhood Hits	93	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

DKK3_MOUSE
NC score	0.064948 (rank : 595)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	270	Target Neighborhood Hits	83	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

ACRO_HUMAN
NC score	0.064911 (rank : 596)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	270	Target Neighborhood Hits	291	Shared Neighborhood Hits	30
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

GNPTA_MOUSE
NC score	0.064762 (rank : 597)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	270	Target Neighborhood Hits	47	Shared Neighborhood Hits	9
SwissProt Accessions	Q69ZN6, Q3U3K6, Q3US34	Gene names	Gnptab, Gnpta, Kiaa1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

ACRO_MOUSE
NC score	0.064546 (rank : 598)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	270	Target Neighborhood Hits	185	Shared Neighborhood Hits	28
SwissProt Accessions	P23578	Gene names	Acr
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

PRS27_MOUSE
NC score	0.064472 (rank : 599)	θ value	θ > 10 (rank : 644)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BJR6	Gene names	Prss27, Mpn
Domain Architecture	No domain graphic available
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin).

TMPSD_MOUSE
NC score	0.064433 (rank : 600)	θ value	θ > 10 (rank : 708)
Query Neighborhood Hits	270	Target Neighborhood Hits	334	Shared Neighborhood Hits	33
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

FA11_MOUSE
NC score	0.064303 (rank : 601)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	270	Target Neighborhood Hits	180	Shared Neighborhood Hits	27
SwissProt Accessions	Q91Y47	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

TRY3_HUMAN
NC score	0.064296 (rank : 602)	θ value	θ > 10 (rank : 720)
Query Neighborhood Hits	270	Target Neighborhood Hits	178	Shared Neighborhood Hits	29
SwissProt Accessions	P35030, P15951, Q15665, Q9UQV3	Gene names	PRSS3, PRSS4, TRY3, TRY4
Domain Architecture
Description	Trypsin-3 precursor (EC 3.4.21.4) (Trypsin III) (Brain trypsinogen) (Mesotrypsinogen) (Trypsin IV).

TMPSD_HUMAN
NC score	0.064289 (rank : 603)	θ value	θ > 10 (rank : 707)
Query Neighborhood Hits	270	Target Neighborhood Hits	333	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

KREM1_HUMAN
NC score	0.064035 (rank : 604)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	270	Target Neighborhood Hits	90	Shared Neighborhood Hits	31
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

TRYG1_MOUSE
NC score	0.063791 (rank : 605)	θ value	θ > 10 (rank : 727)
Query Neighborhood Hits	270	Target Neighborhood Hits	181	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QUL7	Gene names	Tpsg1, Tmt
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

BSSP4_MOUSE
NC score	0.063587 (rank : 606)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	270	Target Neighborhood Hits	179	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ER10	Gene names	Prss22, Bssp4, Prss26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

PLMN_HUMAN
NC score	0.063488 (rank : 607)	θ value	θ > 10 (rank : 639)
Query Neighborhood Hits	270	Target Neighborhood Hits	204	Shared Neighborhood Hits	29
SwissProt Accessions	P00747, Q15146, Q6PA00	Gene names	PLG
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

TRY2_HUMAN
NC score	0.063449 (rank : 608)	θ value	θ > 10 (rank : 718)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	27
SwissProt Accessions	P07478	Gene names	PRSS2, TRY2, TRYP2
Domain Architecture
Description	Trypsin-2 precursor (EC 3.4.21.4) (Trypsin II) (Anionic trypsinogen).

BSSP4_HUMAN
NC score	0.063175 (rank : 609)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	28
SwissProt Accessions	Q9GZN4, O43342, Q6UXE0	Gene names	PRSS22, BSSP4, PRSS26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

APOA_HUMAN
NC score	0.062901 (rank : 610)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	270	Target Neighborhood Hits	221	Shared Neighborhood Hits	31
SwissProt Accessions	P08519	Gene names	LPA
Domain Architecture
Description	Apolipoprotein(a) precursor (EC 3.4.21.-) (Apo(a)) (Lp(a)).

KLK14_HUMAN
NC score	0.062842 (rank : 611)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	270	Target Neighborhood Hits	179	Shared Neighborhood Hits	28
SwissProt Accessions	Q9P0G3	Gene names	KLK14, KLKL6
Domain Architecture
Description	Kallikrein-14 precursor (EC 3.4.21.-) (Kallikrein-like protein 6) (KLK-L6).

KLK6_HUMAN
NC score	0.062842 (rank : 612)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	Q92876	Gene names	KLK6, PRSS18, PRSS9
Domain Architecture
Description	Kallikrein-6 precursor (EC 3.4.21.-) (Protease M) (Neurosin) (Zyme) (SP59).

TRY2_MOUSE
NC score	0.062304 (rank : 613)	θ value	θ > 10 (rank : 719)
Query Neighborhood Hits	270	Target Neighborhood Hits	174	Shared Neighborhood Hits	28
SwissProt Accessions	P07146	Gene names	Prss2, Try2
Domain Architecture
Description	Anionic trypsin-2 precursor (EC 3.4.21.4) (Anionic trypsin II) (Pretrypsinogen II).

KLK13_HUMAN
NC score	0.062246 (rank : 614)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	270	Target Neighborhood Hits	179	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UKR3, Q9Y433	Gene names	KLK13, KLKL4
Domain Architecture
Description	Kallikrein-13 precursor (EC 3.4.21.-) (Kallikrein-like protein 4) (KLK-L4).

SPR2H_MOUSE
NC score	0.062203 (rank : 615)	θ value	θ > 10 (rank : 664)
Query Neighborhood Hits	270	Target Neighborhood Hits	82	Shared Neighborhood Hits	15
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

MCPT6_MOUSE
NC score	0.062004 (rank : 616)	θ value	θ > 10 (rank : 568)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	P21845, Q61962	Gene names	Mcpt6
Domain Architecture
Description	Mast cell protease 6 precursor (EC 3.4.21.59) (MMCP-6) (Tryptase).

DMBT1_HUMAN
NC score	0.061977 (rank : 617)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	270	Target Neighborhood Hits	152	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

TRY1_HUMAN
NC score	0.061865 (rank : 618)	θ value	θ > 10 (rank : 717)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	28
SwissProt Accessions	P07477, Q92955, Q9HAN4, Q9HAN5, Q9HAN6, Q9HAN7	Gene names	PRSS1, TRP1, TRY1, TRYP1
Domain Architecture
Description	Trypsin-1 precursor (EC 3.4.21.4) (Trypsin I) (Cationic trypsinogen).

SPR2G_MOUSE
NC score	0.061729 (rank : 619)	θ value	θ > 10 (rank : 663)
Query Neighborhood Hits	270	Target Neighborhood Hits	53	Shared Neighborhood Hits	15
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

KLK7_MOUSE
NC score	0.061617 (rank : 620)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	Q91VE3, Q9R048	Gene names	Klk7, Prss6, Scce
Domain Architecture	No domain graphic available
Description	Kallikrein-7 precursor (EC 3.4.21.-) (Stratum corneum chymotryptic enzyme) (Thymopsin).

NETR_HUMAN
NC score	0.061500 (rank : 621)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	270	Target Neighborhood Hits	218	Shared Neighborhood Hits	28
SwissProt Accessions	P56730, Q9UP16	Gene names	PRSS12
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Leydin).

RSPO3_MOUSE
NC score	0.061403 (rank : 622)	θ value	θ > 10 (rank : 652)
Query Neighborhood Hits	270	Target Neighborhood Hits	120	Shared Neighborhood Hits	39
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

CYR61_MOUSE
NC score	0.061175 (rank : 623)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	270	Target Neighborhood Hits	156	Shared Neighborhood Hits	39
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

NRPN_HUMAN
NC score	0.060976 (rank : 624)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	270	Target Neighborhood Hits	182	Shared Neighborhood Hits	30
SwissProt Accessions	O60259, Q9HCB3, Q9UIL9, Q9UQ47	Gene names	KLK8, NRPN, PRSS19, TADG14
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8) (Ovasin) (Serine protease TADG-14) (Tumor-associated differentially expressed gene 14 protein).

GP113_HUMAN
NC score	0.060942 (rank : 625)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	270	Target Neighborhood Hits	102	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IZF5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3	Gene names	GPR113, PGR23
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 113 precursor (G-protein coupled receptor PGR23).

NETR_MOUSE
NC score	0.060848 (rank : 626)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	270	Target Neighborhood Hits	216	Shared Neighborhood Hits	29
SwissProt Accessions	O08762	Gene names	Prss12, Bssp3
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Brain-specific serine protease 3) (BSSP-3).

POLS2_MOUSE
NC score	0.060762 (rank : 627)	θ value	θ > 10 (rank : 642)
Query Neighborhood Hits	270	Target Neighborhood Hits	188	Shared Neighborhood Hits	28
SwissProt Accessions	Q5K2P8	Gene names	Prss36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

TSP50_HUMAN
NC score	0.060708 (rank : 628)	θ value	θ > 10 (rank : 734)
Query Neighborhood Hits	270	Target Neighborhood Hits	178	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UI38	Gene names	TSP50
Domain Architecture
Description	Testis-specific protease-like protein 50 precursor.

POLS2_HUMAN
NC score	0.060672 (rank : 629)	θ value	θ > 10 (rank : 641)
Query Neighborhood Hits	270	Target Neighborhood Hits	192	Shared Neighborhood Hits	30
SwissProt Accessions	Q5K4E3, Q8NBY4	Gene names	PRSS36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

TEST_MOUSE
NC score	0.060608 (rank : 630)	θ value	θ > 10 (rank : 677)
Query Neighborhood Hits	270	Target Neighborhood Hits	174	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JHJ7, Q9DA14	Gene names	Prss21
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Tryptase 4).

KLK10_HUMAN
NC score	0.060592 (rank : 631)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	270	Target Neighborhood Hits	178	Shared Neighborhood Hits	28
SwissProt Accessions	O43240, Q99920, Q9GZW9	Gene names	KLK10, NES1, PRRSL1
Domain Architecture
Description	Kallikrein-10 precursor (EC 3.4.21.-) (Protease serine-like 1) (Normal epithelial cell-specific 1).

KLK15_HUMAN
NC score	0.060520 (rank : 632)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	270	Target Neighborhood Hits	180	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H2R5, Q15358, Q9H2R3, Q9H2R4, Q9H2R6, Q9HBG9	Gene names	KLK15
Domain Architecture
Description	Kallikrein-15 precursor (EC 3.4.21.-) (ACO protease).

KREM2_MOUSE
NC score	0.060428 (rank : 633)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	270	Target Neighborhood Hits	90	Shared Neighborhood Hits	29
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

KLK12_HUMAN
NC score	0.060418 (rank : 634)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	270	Target Neighborhood Hits	197	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UKR0, Q9UKR1	Gene names	KLK12, KLKL5
Domain Architecture
Description	Kallikrein-12 precursor (EC 3.4.21.-) (Kallikrein-like protein 5) (KLK-L5).

SPR2F_HUMAN
NC score	0.060391 (rank : 635)	θ value	θ > 10 (rank : 662)
Query Neighborhood Hits	270	Target Neighborhood Hits	33	Shared Neighborhood Hits	12
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

TRYB1_HUMAN
NC score	0.060364 (rank : 636)	θ value	θ > 10 (rank : 722)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	Q15661, Q15663, Q9H2Y4	Gene names	TPSAB1, TPSB1
Domain Architecture
Description	Tryptase beta-1 precursor (EC 3.4.21.59) (Tryptase-1) (Tryptase I).

TRYB2_HUMAN
NC score	0.060364 (rank : 637)	θ value	θ > 10 (rank : 724)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	P20231, O95827, Q15664, Q9UQI6, Q9UQI7	Gene names	TPSB2, TPS2
Domain Architecture
Description	Tryptase beta-2 precursor (EC 3.4.21.59) (Tryptase-2) (Tryptase II).

MT1A_HUMAN
NC score	0.060352 (rank : 638)	θ value	θ > 10 (rank : 584)
Query Neighborhood Hits	270	Target Neighborhood Hits	74	Shared Neighborhood Hits	25
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

TMPS5_MOUSE
NC score	0.060131 (rank : 639)	θ value	θ > 10 (rank : 700)
Query Neighborhood Hits	270	Target Neighborhood Hits	185	Shared Neighborhood Hits	29
SwissProt Accessions	Q9ER04, Q9ER02, Q9ER03	Gene names	Tmprss5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

KLK7_HUMAN
NC score	0.060000 (rank : 640)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	P49862, Q8N5N9, Q8NFV7	Gene names	KLK7, PRSS6, SCCE
Domain Architecture
Description	Kallikrein-7 precursor (EC 3.4.21.-) (hK7) (Stratum corneum chymotryptic enzyme) (hSCCE).

TNR11_HUMAN
NC score	0.059993 (rank : 641)	θ value	θ > 10 (rank : 710)
Query Neighborhood Hits	270	Target Neighborhood Hits	135	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

ELA2A_HUMAN
NC score	0.059976 (rank : 642)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	270	Target Neighborhood Hits	180	Shared Neighborhood Hits	29
SwissProt Accessions	P08217, Q14243	Gene names	ELA2A
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71).

ELA2A_MOUSE
NC score	0.059936 (rank : 643)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	270	Target Neighborhood Hits	178	Shared Neighborhood Hits	28
SwissProt Accessions	P05208	Gene names	Ela2a, Ela-2, Ela2
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71) (Elastase-2).

NRPN_MOUSE
NC score	0.059872 (rank : 644)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	270	Target Neighborhood Hits	186	Shared Neighborhood Hits	30
SwissProt Accessions	Q61955	Gene names	Klk8, Nrpn, Prss19
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8).

ELA2B_HUMAN
NC score	0.059640 (rank : 645)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	270	Target Neighborhood Hits	178	Shared Neighborhood Hits	28
SwissProt Accessions	P08218	Gene names	ELA2B
Domain Architecture
Description	Elastase-2B precursor (EC 3.4.21.71).

TRYB1_MOUSE
NC score	0.059460 (rank : 646)	θ value	θ > 10 (rank : 723)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	Q02844	Gene names	Tpsab1, Mcpt7
Domain Architecture
Description	Tryptase precursor (EC 3.4.21.59) (Mast cell protease 7) (MMCP-7) (Tryptase alpha/beta-1).

TRYA1_HUMAN
NC score	0.059456 (rank : 647)	θ value	θ > 10 (rank : 721)
Query Neighborhood Hits	270	Target Neighborhood Hits	177	Shared Neighborhood Hits	28
SwissProt Accessions	P15157, Q9H2Y5, Q9UQI1	Gene names	TPSAB1, TPS1
Domain Architecture
Description	Tryptase alpha-1 precursor (EC 3.4.21.59) (Tryptase-1).

NRG3_MOUSE
NC score	0.059451 (rank : 648)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	270	Target Neighborhood Hits	132	Shared Neighborhood Hits	49
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

CATG_MOUSE
NC score	0.059322 (rank : 649)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	270	Target Neighborhood Hits	174	Shared Neighborhood Hits	28
SwissProt Accessions	P28293	Gene names	Ctsg
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (Vimentin-specific protease) (VSP).

TMPS5_HUMAN
NC score	0.059116 (rank : 650)	θ value	θ > 10 (rank : 699)
Query Neighborhood Hits	270	Target Neighborhood Hits	181	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H3S3	Gene names	TMPRSS5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

PAPPA_HUMAN
NC score	0.058999 (rank : 651)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	270	Target Neighborhood Hits	161	Shared Neighborhood Hits	44
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

TEST_HUMAN
NC score	0.058727 (rank : 652)	θ value	θ > 10 (rank : 676)
Query Neighborhood Hits	270	Target Neighborhood Hits	172	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y6M0, Q9NS34, Q9P2V6	Gene names	PRSS21, ESP1, TEST1
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Eosinophil serine protease 1) (ESP- 1).

CATG_HUMAN
NC score	0.058716 (rank : 653)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	270	Target Neighborhood Hits	174	Shared Neighborhood Hits	28
SwissProt Accessions	P08311	Gene names	CTSG
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (CG).

KLK11_MOUSE
NC score	0.058710 (rank : 654)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	270	Target Neighborhood Hits	174	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QYN3, Q9QYN4	Gene names	Klk11, Prss20
Domain Architecture	No domain graphic available
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin).

KLK4_HUMAN
NC score	0.058421 (rank : 655)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y5K2, Q4VB16, Q9GZL6, Q9UBJ6	Gene names	KLK4, EMSP1, PRSS17, PSTS
Domain Architecture
Description	Kallikrein-4 precursor (EC 3.4.21.-) (Prostase) (Kallikrein-like protein 1) (KLK-L1) (Enamel matrix serine proteinase 1).

HGFL_HUMAN
NC score	0.058401 (rank : 656)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	270	Target Neighborhood Hits	190	Shared Neighborhood Hits	32
SwissProt Accessions	P26927, Q13350, Q14870	Gene names	MST1, HGFL
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) (Macrophage-stimulating protein) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

CYR61_HUMAN
NC score	0.058210 (rank : 657)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	270	Target Neighborhood Hits	159	Shared Neighborhood Hits	41
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

KLK5_HUMAN
NC score	0.058125 (rank : 658)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	270	Target Neighborhood Hits	182	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y337, Q9HBG8	Gene names	KLK5, SCTE
Domain Architecture
Description	Kallikrein-5 precursor (EC 3.4.21.-) (Stratum corneum tryptic enzyme) (Kallikrein-like protein 2) (KLK-L2).

NEU1_MOUSE
NC score	0.058100 (rank : 659)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	270	Target Neighborhood Hits	64	Shared Neighborhood Hits	31
SwissProt Accessions	P35454	Gene names	Oxt
Domain Architecture
Description	Oxytocin-neurophysin 1 precursor (OT-NPI) [Contains: Oxytocin (Ocytocin); Neurophysin 1].

HGFL_MOUSE
NC score	0.057879 (rank : 660)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	270	Target Neighborhood Hits	188	Shared Neighborhood Hits	30
SwissProt Accessions	P26928	Gene names	Mst1, Hgfl
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

CTGF_HUMAN
NC score	0.057709 (rank : 661)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	270	Target Neighborhood Hits	128	Shared Neighborhood Hits	33
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

GP125_HUMAN
NC score	0.057572 (rank : 662)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	270	Target Neighborhood Hits	327	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

NRG3_HUMAN
NC score	0.057454 (rank : 663)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	270	Target Neighborhood Hits	119	Shared Neighborhood Hits	46
SwissProt Accessions	P56975	Gene names	NRG3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

KLK11_HUMAN
NC score	0.057373 (rank : 664)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	270	Target Neighborhood Hits	174	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UBX7, O75837, Q9NS65	Gene names	KLK11, PRSS20, TLSP
Domain Architecture
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin) (Trypsin-like protease).

ELA1_HUMAN
NC score	0.057017 (rank : 665)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	270	Target Neighborhood Hits	178	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UNI1, Q5MLF0, Q6DJT0, Q6ISM6	Gene names	ELA1
Domain Architecture
Description	Elastase-1 precursor (EC 3.4.21.36).

K1KB9_MOUSE
NC score	0.056663 (rank : 666)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	28
SwissProt Accessions	P15949	Gene names	Klk1b9, Egfbp3, Klk-9, Klk9
Domain Architecture
Description	Kallikrein 1-related peptidase b9 precursor (EC 3.4.21.35) (Tissue kallikrein-9) (Glandular kallikrein K9) (mGK-9) (Epidermal growth factor-binding protein type C) (EGF-BP C).

GRAH_HUMAN
NC score	0.056459 (rank : 667)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	P20718	Gene names	GZMH, CGL2, CTSGL2
Domain Architecture
Description	Granzyme H precursor (EC 3.4.21.-) (Cytotoxic T-lymphocyte proteinase) (Cathepsin G-like 2) (CTSGL2) (CCP-X) (Cytotoxic serine protease C) (CSP-C).

KLK9_HUMAN
NC score	0.056415 (rank : 668)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UKQ9	Gene names	KLK9
Domain Architecture
Description	Kallikrein-9 precursor (EC 3.4.21.-) (Kallikrein-like protein 3) (KLK- L3).

TNR8_MOUSE
NC score	0.056353 (rank : 669)	θ value	θ > 10 (rank : 715)
Query Neighborhood Hits	270	Target Neighborhood Hits	208	Shared Neighborhood Hits	41
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

MT1B_HUMAN
NC score	0.056266 (rank : 670)	θ value	θ > 10 (rank : 585)
Query Neighborhood Hits	270	Target Neighborhood Hits	87	Shared Neighborhood Hits	34
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

GP124_MOUSE
NC score	0.055992 (rank : 671)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	270	Target Neighborhood Hits	423	Shared Neighborhood Hits	25
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GRAM_HUMAN
NC score	0.055825 (rank : 672)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	270	Target Neighborhood Hits	174	Shared Neighborhood Hits	28
SwissProt Accessions	P51124	Gene names	GZMM, MET1
Domain Architecture
Description	Granzyme M precursor (EC 3.4.21.-) (Met-ase) (Natural killer cell granular protease) (HU-Met-1) (Met-1 serine protease).

CFAD_HUMAN
NC score	0.055771 (rank : 673)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	27
SwissProt Accessions	P00746	Gene names	CFD, DF
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin).

KLK3_HUMAN
NC score	0.055763 (rank : 674)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	28
SwissProt Accessions	P07288, Q16272, Q86TG8	Gene names	KLK3, APS
Domain Architecture
Description	Prostate-specific antigen precursor (EC 3.4.21.77) (PSA) (Kallikrein- 3) (Semenogelase) (Gamma-seminoprotein) (Seminin) (P-30 antigen).

GP144_HUMAN
NC score	0.055680 (rank : 675)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	270	Target Neighborhood Hits	108	Shared Neighborhood Hits	15
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

TGFA_MOUSE
NC score	0.055676 (rank : 676)	θ value	θ > 10 (rank : 679)
Query Neighborhood Hits	270	Target Neighborhood Hits	62	Shared Neighborhood Hits	33
SwissProt Accessions	P48030	Gene names	Tgfa
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

TRYD_HUMAN
NC score	0.055610 (rank : 677)	θ value	θ > 10 (rank : 725)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BZJ3, O95824, Q8TDI6, Q96L36, Q96RZ5, Q9H2Y6, Q9UQI8	Gene names	TPSD1
Domain Architecture
Description	Tryptase delta precursor (EC 3.4.21.59) (Delta tryptase) (Mast cell mMCP-7-like) (Tryptase-3) (HmMCP-3-like tryptase III).

CFAD_MOUSE
NC score	0.055585 (rank : 678)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	270	Target Neighborhood Hits	177	Shared Neighborhood Hits	27
SwissProt Accessions	P03953, Q61280	Gene names	Cfd, Adn, Df
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin) (28 kDa adipocyte protein).

RSPO4_HUMAN
NC score	0.055411 (rank : 679)	θ value	θ > 10 (rank : 653)
Query Neighborhood Hits	270	Target Neighborhood Hits	110	Shared Neighborhood Hits	39
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

LCE5A_HUMAN
NC score	0.054995 (rank : 680)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	270	Target Neighborhood Hits	43	Shared Neighborhood Hits	9
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

K1B11_MOUSE
NC score	0.054935 (rank : 681)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	270	Target Neighborhood Hits	180	Shared Neighborhood Hits	28
SwissProt Accessions	P15946	Gene names	Klk1b11, Klk-11, Klk11
Domain Architecture
Description	Kallikrein 1-related peptidase b11 precursor (EC 3.4.21.35) (Tissue kallikrein-11) (Glandular kallikrein K11) (mGK-11).

GP133_HUMAN
NC score	0.054791 (rank : 682)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	270	Target Neighborhood Hits	115	Shared Neighborhood Hits	13
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

GRAD_MOUSE
NC score	0.054703 (rank : 683)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	270	Target Neighborhood Hits	173	Shared Neighborhood Hits	28
SwissProt Accessions	P11033, P97387	Gene names	Gzmd
Domain Architecture
Description	Granzyme D precursor (EC 3.4.21.-).

KLK1_MOUSE
NC score	0.054641 (rank : 684)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	270	Target Neighborhood Hits	179	Shared Neighborhood Hits	28
SwissProt Accessions	P15947, Q61855	Gene names	Klk1, Klk-6, Klk6
Domain Architecture
Description	Glandular kallikrein K1 precursor (EC 3.4.21.35) (Tissue kallikrein-6) (mGK-6) (Renal kallikrein) (KAL-B).

KLK2_HUMAN
NC score	0.054454 (rank : 685)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	28
SwissProt Accessions	P20151, Q15946, Q9UJZ9	Gene names	KLK2
Domain Architecture
Description	Kallikrein-2 precursor (EC 3.4.21.35) (Tissue kallikrein-2) (Glandular kallikrein-1) (hGK-1).

K1KB3_MOUSE
NC score	0.054380 (rank : 686)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	270	Target Neighborhood Hits	179	Shared Neighborhood Hits	28
SwissProt Accessions	P00756	Gene names	Klk1b3, Klk-3, Klk3, Ngfg
Domain Architecture
Description	Kallikrein 1-related peptidase b3 precursor (EC 3.4.21.35) (Glandular kallikrein K3) (Tissue kallikrein-3) (mGK-3) (7S nerve growth factor gamma chain) (Gamma-NGF) [Contains: Nerve growth factor gamma chain 1; Nerve growth factor gamma chain 2].

AD26A_MOUSE
NC score	0.054323 (rank : 687)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	270	Target Neighborhood Hits	165	Shared Neighborhood Hits	61
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

GP125_MOUSE
NC score	0.054249 (rank : 688)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	270	Target Neighborhood Hits	329	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

GP124_HUMAN
NC score	0.054139 (rank : 689)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	270	Target Neighborhood Hits	304	Shared Neighborhood Hits	20
SwissProt Accessions	Q96PE1, Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4	Gene names	GPR124, KIAA1531, TEM5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GRAE_MOUSE
NC score	0.054074 (rank : 690)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	270	Target Neighborhood Hits	172	Shared Neighborhood Hits	28
SwissProt Accessions	P08884, P97389	Gene names	Gzme, Ccp3, Ctla-6, Ctla6
Domain Architecture
Description	Granzyme E precursor (EC 3.4.21.-) (Cytotoxic cell protease 3) (CCP3) (CTL serine protease 2) (D12) (Cytotoxic serine protease 2) (MCSP2).

GRAG_MOUSE
NC score	0.054018 (rank : 691)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	270	Target Neighborhood Hits	173	Shared Neighborhood Hits	28
SwissProt Accessions	P13366, P97388	Gene names	Gzmg
Domain Architecture
Description	Granzyme G precursor (EC 3.4.21.-) (CTL serine protease 1) (MCSP-1).

K1KB1_MOUSE
NC score	0.053882 (rank : 692)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	270	Target Neighborhood Hits	180	Shared Neighborhood Hits	28
SwissProt Accessions	P00755	Gene names	Klk1b1, Klk-1, Klk1
Domain Architecture
Description	Kallikrein 1-related peptidase b1 precursor (EC 3.4.21.35) (Glandular kallikrein K1) (Tissue kallikrein-1) (mGK-1).

GRAK_MOUSE
NC score	0.053743 (rank : 693)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	270	Target Neighborhood Hits	174	Shared Neighborhood Hits	27
SwissProt Accessions	O35205	Gene names	Gzmk
Domain Architecture
Description	Granzyme K precursor (EC 3.4.21.-).

CDN2B_HUMAN
NC score	0.053740 (rank : 694)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	270	Target Neighborhood Hits	196	Shared Neighborhood Hits	8
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

CD2A1_MOUSE
NC score	0.053636 (rank : 695)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	270	Target Neighborhood Hits	206	Shared Neighborhood Hits	8
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

ELA3A_HUMAN
NC score	0.053569 (rank : 696)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	270	Target Neighborhood Hits	173	Shared Neighborhood Hits	27
SwissProt Accessions	P09093, Q9BRW4	Gene names	ELA3A, ELA3
Domain Architecture
Description	Elastase-3A precursor (EC 3.4.21.70) (Elastase IIIA) (Protease E).

DKK3_HUMAN
NC score	0.053435 (rank : 697)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	270	Target Neighborhood Hits	74	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UBP4, Q9ULB7	Gene names	DKK3, REIC
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3).

GRAC_MOUSE
NC score	0.053347 (rank : 698)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	270	Target Neighborhood Hits	177	Shared Neighborhood Hits	28
SwissProt Accessions	P08882, Q61389	Gene names	Gzmc, Ctla-5, Ctla5
Domain Architecture
Description	Granzyme C precursor (EC 3.4.21.-) (Cytotoxic cell protease 2) (CCP2) (B10).

MCPT1_MOUSE
NC score	0.053279 (rank : 699)	θ value	θ > 10 (rank : 565)
Query Neighborhood Hits	270	Target Neighborhood Hits	177	Shared Neighborhood Hits	28
SwissProt Accessions	P11034	Gene names	Mcpt1
Domain Architecture
Description	Mast cell protease 1 precursor (EC 3.4.21.-) (MMCP-1).

K1KB5_MOUSE
NC score	0.053247 (rank : 700)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	270	Target Neighborhood Hits	177	Shared Neighborhood Hits	28
SwissProt Accessions	P15945, Q52KM1, Q565D7	Gene names	Klk1b5, Klk-5, Klk5
Domain Architecture
Description	Kallikrein 1-related peptidase b5 precursor (EC 3.4.21.35) (Glandular kallikrein K5) (Tissue kallikrein-5) (mGK-5).

CTGF_MOUSE
NC score	0.053174 (rank : 701)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	270	Target Neighborhood Hits	124	Shared Neighborhood Hits	29
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

K1KB4_MOUSE
NC score	0.053146 (rank : 702)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	270	Target Neighborhood Hits	177	Shared Neighborhood Hits	28
SwissProt Accessions	P00757	Gene names	Klk1b4, Klk-4, Klk4, Ngfa
Domain Architecture
Description	Kallikrein 1-related peptidase-like b4 precursor (7S nerve growth factor alpha chain) (Alpha-NGF).

TNR7_HUMAN
NC score	0.053137 (rank : 703)	θ value	θ > 10 (rank : 714)
Query Neighborhood Hits	270	Target Neighborhood Hits	120	Shared Neighborhood Hits	40
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

LPHN2_HUMAN
NC score	0.052966 (rank : 704)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	270	Target Neighborhood Hits	136	Shared Neighborhood Hits	13
SwissProt Accessions	O95490, O94882, Q5VX76, Q9UKY5, Q9UKY6	Gene names	LPHN2, KIAA0786, LEC1, LPHH1
Domain Architecture
Description	Latrophilin-2 precursor (Calcium-independent alpha-latrotoxin receptor 2) (Latrophilin homolog 1) (Lectomedin-1).

K1B22_MOUSE
NC score	0.052942 (rank : 705)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	270	Target Neighborhood Hits	174	Shared Neighborhood Hits	28
SwissProt Accessions	P15948	Gene names	Klk1b22, Klk-22, Klk22
Domain Architecture
Description	Kallikrein 1-related peptidase b22 precursor (EC 3.4.21.35) (Glandular kallikrein K22) (Tissue kallikrein 22) (mGK-22) (Epidermal growth factor-binding protein type A) (EGF-BP A) (Nerve growth factor beta chain endopeptidase) (Beta-NGF-endopeptidase).

K1B21_MOUSE
NC score	0.052844 (rank : 706)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	270	Target Neighborhood Hits	179	Shared Neighborhood Hits	28
SwissProt Accessions	Q61759, Q61760, Q9JM70	Gene names	Klk1b21, Klk-21, Klk21
Domain Architecture
Description	Kallikrein 1-related peptidase b21 precursor (EC 3.4.21.35) (Tissue kallikrein 21) (Glandular kallikrein K21) (mGK-21).

ASTL_HUMAN
NC score	0.052416 (rank : 707)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	270	Target Neighborhood Hits	252	Shared Neighborhood Hits	12
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

ELA3B_HUMAN
NC score	0.052414 (rank : 708)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	27
SwissProt Accessions	P08861, P11423, Q5VU28, Q5VU29, Q5VU30	Gene names	ELA3B
Domain Architecture
Description	Elastase-3B precursor (EC 3.4.21.70) (Elastase IIIB) (Protease E).

SPIT1_HUMAN
NC score	0.052387 (rank : 709)	θ value	θ > 10 (rank : 660)
Query Neighborhood Hits	270	Target Neighborhood Hits	100	Shared Neighborhood Hits	28
SwissProt Accessions	O43278, Q7Z7D2	Gene names	SPINT1, HAI1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

LPHN1_HUMAN
NC score	0.052373 (rank : 710)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	270	Target Neighborhood Hits	155	Shared Neighborhood Hits	13
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

MCPT1_HUMAN
NC score	0.052369 (rank : 711)	θ value	θ > 10 (rank : 564)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	28
SwissProt Accessions	P23946, Q16018	Gene names	CMA1, CYH, CYM
Domain Architecture
Description	Chymase precursor (EC 3.4.21.39) (Mast cell protease I).

K1B24_MOUSE
NC score	0.052273 (rank : 712)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	270	Target Neighborhood Hits	180	Shared Neighborhood Hits	28
SwissProt Accessions	Q61754, Q61755, Q9JM69	Gene names	Klk1b24, Klk-24, Klk24
Domain Architecture
Description	Kallikrein 1-related peptidase b24 precursor (EC 3.4.21.35) (Glandular kallikrein K24) (Tissue kallikrein 24) (mGK-24).

GRAF_MOUSE
NC score	0.052174 (rank : 713)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	270	Target Neighborhood Hits	172	Shared Neighborhood Hits	28
SwissProt Accessions	P08883	Gene names	Gzmf, Ccp4, Ctla-7, Ctla7
Domain Architecture
Description	Granzyme F precursor (EC 3.4.21.-) (Cytotoxic cell protease 4) (CCP4) (CTL serine protease 3) (C134) (Cytotoxic serine protease 3) (MCSP3).

LPHN3_HUMAN
NC score	0.052099 (rank : 714)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	270	Target Neighborhood Hits	139	Shared Neighborhood Hits	14
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

K1B26_MOUSE
NC score	0.052065 (rank : 715)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	270	Target Neighborhood Hits	177	Shared Neighborhood Hits	28
SwissProt Accessions	P36369, P00753, P00754	Gene names	Klk1b26, Klk-26, Klk26
Domain Architecture
Description	Kallikrein 1-related peptidase b26 precursor (EC 3.4.21.35) (Glandular kallikrein K26) (Tissue kallikrein 26) (mGK-26) (Prorenin-converting enzyme 2) (PRECE-2).

K1B27_MOUSE
NC score	0.052026 (rank : 716)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JM71	Gene names	Klk1b27, Klk-27, Klk27
Domain Architecture
Description	Kallikrein 1-related peptidase b27 precursor (EC 3.4.21.-) (Tissue kallikrein 27) (Glandular kallikrein K27) (mGK-27) (mKlk27).

PRTN3_HUMAN
NC score	0.051708 (rank : 717)	θ value	θ > 10 (rank : 647)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	P24158, P15637, P18078, Q6LBM7, Q9UQD8	Gene names	PRTN3, MBN
Domain Architecture
Description	Myeloblastin precursor (EC 3.4.21.76) (Leukocyte proteinase 3) (PR-3) (PR3) (AGP7) (Wegener autoantigen) (P29) (C-ANCA antigen) (Neutrophil proteinase 4) (NP-4).

EGFB2_MOUSE
NC score	0.051659 (rank : 718)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	270	Target Neighborhood Hits	176	Shared Neighborhood Hits	28
SwissProt Accessions	P36368, P00754	Gene names	Egfbp2, Egfbp-2, Klk-13, Klk13
Domain Architecture
Description	Epidermal growth factor-binding protein type B precursor (EC 3.4.21.35) (EGF-BP B) (Glandular kallikrein K13) (Tissue kallikrein 13) (mGK-13) (Prorenin-converting enzyme) (PRECE).

KR221_HUMAN
NC score	0.051577 (rank : 719)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	270	Target Neighborhood Hits	6	Shared Neighborhood Hits	5
SwissProt Accessions	Q3MIV0	Gene names	KRTAP22-1, KAP22.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 22-1.

BAI1_HUMAN
NC score	0.051494 (rank : 720)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	270	Target Neighborhood Hits	375	Shared Neighborhood Hits	30
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

K1KB8_MOUSE
NC score	0.051456 (rank : 721)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	270	Target Neighborhood Hits	177	Shared Neighborhood Hits	28
SwissProt Accessions	P07628	Gene names	Klk1b8, Klk-8, Klk8
Domain Architecture
Description	Kallikrein 1-related peptidase b8 precursor (EC 3.4.21.35) (Tissue kallikrein-8) (Glandular kallikrein K8) (mGK-8).

MCPT8_MOUSE
NC score	0.051275 (rank : 722)	θ value	θ > 10 (rank : 569)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	P43430, Q9R1F1	Gene names	Mcpt8
Domain Architecture
Description	Mast cell protease 8 precursor (EC 3.4.21.-) (MMCP-8).

MCPT2_MOUSE
NC score	0.051258 (rank : 723)	θ value	θ > 10 (rank : 566)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	P15119	Gene names	Mcpt2
Domain Architecture
Description	Mast cell protease 2 precursor (EC 3.4.21.-) (MMCP-2).

WISP2_HUMAN
NC score	0.051238 (rank : 724)	θ value	θ > 10 (rank : 744)
Query Neighborhood Hits	270	Target Neighborhood Hits	126	Shared Neighborhood Hits	25
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

GPR64_MOUSE
NC score	0.051173 (rank : 725)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	270	Target Neighborhood Hits	156	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

PRTN3_MOUSE
NC score	0.050704 (rank : 726)	θ value	θ > 10 (rank : 648)
Query Neighborhood Hits	270	Target Neighborhood Hits	177	Shared Neighborhood Hits	28
SwissProt Accessions	Q61096, O08809	Gene names	Prtn3
Domain Architecture
Description	Myeloblastin precursor (EC 3.4.21.76) (Proteinase 3) (PR-3).

MCPT4_MOUSE
NC score	0.050652 (rank : 727)	θ value	θ > 10 (rank : 567)
Query Neighborhood Hits	270	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	P21812, Q9EPQ9, Q9EQT2	Gene names	Mcpt4
Domain Architecture
Description	Mast cell protease 4 precursor (EC 3.4.21.-) (MMCP-4) (Serosal mast cell protease) (MSMCP) (Myonase).

GP116_HUMAN
NC score	0.050580 (rank : 728)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	270	Target Neighborhood Hits	167	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

MCPT9_MOUSE
NC score	0.050455 (rank : 729)	θ value	θ > 10 (rank : 570)
Query Neighborhood Hits	270	Target Neighborhood Hits	174	Shared Neighborhood Hits	28
SwissProt Accessions	O35164	Gene names	Mcpt9
Domain Architecture
Description	Mast cell protease 9 precursor (EC 3.4.21.-) (MMCP-9).

ADA20_HUMAN
NC score	0.050452 (rank : 730)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	270	Target Neighborhood Hits	143	Shared Neighborhood Hits	49
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

KLK1_HUMAN
NC score	0.050275 (rank : 731)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	270	Target Neighborhood Hits	183	Shared Neighborhood Hits	27
SwissProt Accessions	P06870, Q8TCV8, Q9BS53, Q9NQU4, Q9UMJ1	Gene names	KLK1
Domain Architecture
Description	Kallikrein-1 precursor (EC 3.4.21.35) (Tissue kallikrein) (Kidney/pancreas/salivary gland kallikrein).

GP114_HUMAN
NC score	0.050217 (rank : 732)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	270	Target Neighborhood Hits	75	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IZF4, Q6ZMH7, Q6ZML4, Q86SL8, Q8IZ14	Gene names	GPR114, PGR27
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 114 precursor (G-protein coupled receptor PGR27).

XLKD1_MOUSE
NC score	0.050201 (rank : 733)	θ value	θ > 10 (rank : 745)
Query Neighborhood Hits	270	Target Neighborhood Hits	31	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BHC0, Q3TUC1, Q99NE4	Gene names	Xlkd1, Crsbp1
Domain Architecture	No domain graphic available
Description	Lymphatic vessel endothelial hyaluronic acid receptor 1 precursor (LYVE-1) (Cell surface retention sequence-binding protein 1) (CRSBP-1) (Extracellular link domain-containing protein 1).

SEPP1_HUMAN
NC score	0.019995 (rank : 734)	θ value	8.99809 (rank : 268)
Query Neighborhood Hits	270	Target Neighborhood Hits	28	Shared Neighborhood Hits	7
SwissProt Accessions	P49908, Q6PD59, Q6PI43, Q6PI87, Q6PJF9	Gene names	SEPP1, SELP
Domain Architecture
Description	Selenoprotein P precursor (SeP).

CU005_HUMAN
NC score	0.016849 (rank : 735)	θ value	4.03905 (rank : 241)
Query Neighborhood Hits	270	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y3R5, Q9UEZ3	Gene names	C21orf5, KIAA0933
Domain Architecture
Description	Protein C21orf5.

VEGFD_HUMAN
NC score	0.011980 (rank : 736)	θ value	8.99809 (rank : 270)
Query Neighborhood Hits	270	Target Neighborhood Hits	48	Shared Neighborhood Hits	12
SwissProt Accessions	O43915	Gene names	FIGF, VEGFD
Domain Architecture
Description	Vascular endothelial growth factor D precursor (VEGF-D) (c-fos-induced growth factor) (FIGF).

ZFY27_MOUSE
NC score	0.007646 (rank : 737)	θ value	6.88961 (rank : 258)
Query Neighborhood Hits	270	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q3TXX3, Q8CFP8	Gene names	Zfyve27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

ALK_HUMAN
NC score	0.006083 (rank : 738)	θ value	3.0926 (rank : 232)
Query Neighborhood Hits	270	Target Neighborhood Hits	795	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

ALK_MOUSE
NC score	0.005716 (rank : 739)	θ value	4.03905 (rank : 238)
Query Neighborhood Hits	270	Target Neighborhood Hits	811	Shared Neighborhood Hits	26
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

5HT3R_MOUSE
NC score	0.004553 (rank : 740)	θ value	1.38821 (rank : 214)
Query Neighborhood Hits	270	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	P23979, Q61225, Q61226	Gene names	Htr3a, 5ht3, Htr3
Domain Architecture
Description	5-hydroxytryptamine 3 receptor precursor (5-HT-3) (Serotonin-gated ion channel receptor) (5-HT3R).

MYH10_MOUSE
NC score	-0.001856 (rank : 741)	θ value	1.38821 (rank : 223)
Query Neighborhood Hits	270	Target Neighborhood Hits	1612	Shared Neighborhood Hits	13
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_HUMAN
NC score	-0.001861 (rank : 742)	θ value	1.38821 (rank : 222)
Query Neighborhood Hits	270	Target Neighborhood Hits	1620	Shared Neighborhood Hits	13
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

LMNA_HUMAN
NC score	-0.002263 (rank : 743)	θ value	6.88961 (rank : 255)
Query Neighborhood Hits	270	Target Neighborhood Hits	653	Shared Neighborhood Hits	10
SwissProt Accessions	P02545, P02546, Q969I8, Q96JA2	Gene names	LMNA, LMN1
Domain Architecture
Description	Lamin-A/C (70 kDa lamin) (NY-REN-32 antigen).

LMNA_MOUSE
NC score	-0.002463 (rank : 744)	θ value	6.88961 (rank : 256)
Query Neighborhood Hits	270	Target Neighborhood Hits	661	Shared Neighborhood Hits	9
SwissProt Accessions	P48678, P11516, P97859, Q3TIH0, Q3TTS8, Q3UCA0, Q3UCJ8, Q91WF2, Q9DC21	Gene names	Lmna, Lmn1
Domain Architecture
Description	Lamin-A/C.

RRBP1_HUMAN
NC score	-0.003694 (rank : 745)	θ value	6.88961 (rank : 257)
Query Neighborhood Hits	270	Target Neighborhood Hits	1306	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

5HT4R_HUMAN
NC score	-0.008620 (rank : 746)	θ value	4.03905 (rank : 237)
Query Neighborhood Hits	270	Target Neighborhood Hits	854	Shared Neighborhood Hits	3
SwissProt Accessions	Q13639, Q96KH9, Q96KI0, Q9H199, Q9NY73, Q9UBM6, Q9UBT4, Q9UE22, Q9UE23, Q9UQR6	Gene names	HTR4
Domain Architecture
Description	5-hydroxytryptamine 4 receptor (5-HT-4) (Serotonin receptor 4) (5- HT4).

5HT4R_MOUSE
NC score	-0.009315 (rank : 747)	θ value	8.99809 (rank : 259)
Query Neighborhood Hits	270	Target Neighborhood Hits	856	Shared Neighborhood Hits	3
SwissProt Accessions	P97288, O89003, O89004, Q9R2A4	Gene names	Htr4
Domain Architecture
Description	5-hydroxytryptamine 4 receptor (5-HT-4) (Serotonin receptor 4) (5- HT4).